Sample records for shift mapping experiments

  1. Motion-induced error reduction by combining Fourier transform profilometry with phase-shifting profilometry.

    PubMed

    Li, Beiwen; Liu, Ziping; Zhang, Song

    2016-10-03

    We propose a hybrid computational framework to reduce motion-induced measurement error by combining the Fourier transform profilometry (FTP) and phase-shifting profilometry (PSP). The proposed method is composed of three major steps: Step 1 is to extract continuous relative phase maps for each isolated object with single-shot FTP method and spatial phase unwrapping; Step 2 is to obtain an absolute phase map of the entire scene using PSP method, albeit motion-induced errors exist on the extracted absolute phase map; and Step 3 is to shift the continuous relative phase maps from Step 1 to generate final absolute phase maps for each isolated object by referring to the absolute phase map with error from Step 2. Experiments demonstrate the success of the proposed computational framework for measuring multiple isolated rapidly moving objects.

  2. The VLAB OER Experience: Modeling Potential-Adopter Student Acceptance

    ERIC Educational Resources Information Center

    Raman, Raghu; Achuthan, Krishnashree; Nedungadi, Prema; Diwakar, Shyam; Bose, Ranjan

    2014-01-01

    Virtual Labs (VLAB) is a multi-institutional Open Educational Resources (OER) initiative, exclusively focused on lab experiments for engineering education. This project envisages building a large OER repository, containing over 1650 virtual experiments mapped to the engineering curriculum. The introduction of VLAB is a paradigm shift in an…

  3. Shifting from Fear to Self-Confidence: Body Mapping as a Transformative Tool in Music Teacher Education

    ERIC Educational Resources Information Center

    Griffin, Shelley M.

    2015-01-01

    Fear and lack of self-confidence toward music teaching are frequently experienced by many Bachelor of Education teacher candidates when they imagine themselves as future elementary general music teachers. Integrating visual art body mapping in elementary music methods fosters a unique opportunity to identify and interrogate musical experience.…

  4. Correction of Proton Resonance Frequency Shift Temperature Maps for Magnetic Field Disturbances Caused by Breathing

    NASA Astrophysics Data System (ADS)

    Shmatukha, Andriy V.; Bakker, Chris J. G.

    2006-05-01

    Respiratory Induced Resonance Offset (RIRO) is a periodic disturbance of the magnetic field due to breathing. Such disturbances handicap the accuracy of the Proton Resonance Frequency Shift (PRFS) method of MRI temperature mapping in anatomies situated nearby the lungs and chest wall. In this work, we propose a method capable of minimizing errors caused by RIRO in PRFS temperature maps. In this method, a set of baseline images characterizing RIRO at a variety of respiratory cycle instants is acquired before the thermal treatment starts. During the treatment, the temperature evolution is found from two successive images. Then, the calculated temperature changes are corrected for the additional contribution caused by RIRO using the pre-treatment baseline images acquired at the identical instances of the respiratory cycle. Our method is shown to improve the accuracy and stability of PRFS temperature maps in the presence of RIRO and motion in phantom and volunteer experiments.

  5. Mapping Physiological Suitability Limits for Malaria in Africa Under Climate Change.

    PubMed

    Ryan, Sadie J; McNally, Amy; Johnson, Leah R; Mordecai, Erin A; Ben-Horin, Tal; Paaijmans, Krijn; Lafferty, Kevin D

    2015-12-01

    We mapped current and future temperature suitability for malaria transmission in Africa using a published model that incorporates nonlinear physiological responses to temperature of the mosquito vector Anopheles gambiae and the malaria parasite Plasmodium falciparum. We found that a larger area of Africa currently experiences the ideal temperature for transmission than previously supposed. Under future climate projections, we predicted a modest increase in the overall area suitable for malaria transmission, but a net decrease in the most suitable area. Combined with human population density projections, our maps suggest that areas with temperatures suitable for year-round, highest-risk transmission will shift from coastal West Africa to the Albertine Rift between the Democratic Republic of Congo and Uganda, whereas areas with seasonal transmission suitability will shift toward sub-Saharan coastal areas. Mapping temperature suitability places important bounds on malaria transmissibility and, along with local level demographic, socioeconomic, and ecological factors, can indicate where resources may be best spent on malaria control.

  6. Mapping physiological suitability limits for malaria in Africa under climate change

    USGS Publications Warehouse

    Ryan, Sadie J.; McNally, Amy; Johnson, Leah R.; Mordecai, Erin A.; Ben-Horin, Tal; Paaijmans, Krijn P.; Lafferty, Kevin D.

    2015-01-01

    We mapped current and future temperature suitability for malaria transmission in Africa using a published model that incorporates nonlinear physiological responses to temperature of the mosquito vector Anopheles gambiae and the malaria parasite Plasmodium falciparum. We found that a larger area of Africa currently experiences the ideal temperature for transmission than previously supposed. Under future climate projections, we predicted a modest increase in the overall area suitable for malaria transmission, but a net decrease in the most suitable area. Combined with human population density projections, our maps suggest that areas with temperatures suitable for year-round, highest-risk transmission will shift from coastal West Africa to the Albertine Rift between the Democratic Republic of Congo and Uganda, whereas areas with seasonal transmission suitability will shift toward sub-Saharan coastal areas. Mapping temperature suitability places important bounds on malaria transmissibility and, along with local level demographic, socioeconomic, and ecological factors, can indicate where resources may be best spent on malaria control.

  7. Varieties of quantity estimation in children.

    PubMed

    Sella, Francesco; Berteletti, Ilaria; Lucangeli, Daniela; Zorzi, Marco

    2015-06-01

    In the number-to-position task, with increasing age and numerical expertise, children's pattern of estimates shifts from a biased (nonlinear) to a formal (linear) mapping. This widely replicated finding concerns symbolic numbers, whereas less is known about other types of quantity estimation. In Experiment 1, Preschool, Grade 1, and Grade 3 children were asked to map continuous quantities, discrete nonsymbolic quantities (numerosities), and symbolic (Arabic) numbers onto a visual line. Numerical quantity was matched for the symbolic and discrete nonsymbolic conditions, whereas cumulative surface area was matched for the continuous and discrete quantity conditions. Crucially, in the discrete condition children's estimation could rely either on the cumulative area or numerosity. All children showed a linear mapping for continuous quantities, whereas a developmental shift from a logarithmic to a linear mapping was observed for both nonsymbolic and symbolic numerical quantities. Analyses on individual estimates suggested the presence of two distinct strategies in estimating discrete nonsymbolic quantities: one based on numerosity and the other based on spatial extent. In Experiment 2, a non-spatial continuous quantity (shades of gray) and new discrete nonsymbolic conditions were added to the set used in Experiment 1. Results confirmed the linear patterns for the continuous tasks, as well as the presence of a subset of children relying on numerosity for the discrete nonsymbolic numerosity conditions despite the availability of continuous visual cues. Overall, our findings demonstrate that estimation of numerical and non-numerical quantities is based on different processing strategies and follow different developmental trajectories. (c) 2015 APA, all rights reserved).

  8. Sensory experience modifies feature map relationships in visual cortex

    PubMed Central

    Cloherty, Shaun L; Hughes, Nicholas J; Hietanen, Markus A; Bhagavatula, Partha S

    2016-01-01

    The extent to which brain structure is influenced by sensory input during development is a critical but controversial question. A paradigmatic system for studying this is the mammalian visual cortex. Maps of orientation preference (OP) and ocular dominance (OD) in the primary visual cortex of ferrets, cats and monkeys can be individually changed by altered visual input. However, the spatial relationship between OP and OD maps has appeared immutable. Using a computational model we predicted that biasing the visual input to orthogonal orientation in the two eyes should cause a shift of OP pinwheels towards the border of OD columns. We then confirmed this prediction by rearing cats wearing orthogonally oriented cylindrical lenses over each eye. Thus, the spatial relationship between OP and OD maps can be modified by visual experience, revealing a previously unknown degree of brain plasticity in response to sensory input. DOI: http://dx.doi.org/10.7554/eLife.13911.001 PMID:27310531

  9. Are numbers, size and brightness equally efficient in orienting visual attention? Evidence from an eye-tracking study.

    PubMed

    Bulf, Hermann; Macchi Cassia, Viola; de Hevia, Maria Dolores

    2014-01-01

    A number of studies have shown strong relations between numbers and oriented spatial codes. For example, perceiving numbers causes spatial shifts of attention depending upon numbers' magnitude, in a way suggestive of a spatially oriented, mental representation of numbers. Here, we investigated whether this phenomenon extends to non-symbolic numbers, as well as to the processing of the continuous dimensions of size and brightness, exploring whether different quantitative dimensions are equally mapped onto space. After a numerical (symbolic Arabic digits or non-symbolic arrays of dots; Experiment 1) or a non-numerical cue (shapes of different size or brightness level; Experiment 2) was presented, participants' saccadic response to a target that could appear either on the left or the right side of the screen was registered using an automated eye-tracker system. Experiment 1 showed that, both in the case of Arabic digits and dot arrays, right targets were detected faster when preceded by large numbers, and left targets were detected faster when preceded by small numbers. Participants in Experiment 2 were faster at detecting right targets when cued by large-sized shapes and left targets when cued by small-sized shapes, whereas brightness cues did not modulate the detection of peripheral targets. These findings indicate that looking at a symbolic or a non-symbolic number induces attentional shifts to a peripheral region of space that is congruent with the numbers' relative position on a mental number line, and that a similar shift in visual attention is induced by looking at shapes of different size. More specifically, results suggest that, while the dimensions of number and size spontaneously map onto an oriented space, the dimension of brightness seems to be independent at a certain level of magnitude elaboration from the dimensions of spatial extent and number, indicating that not all continuous dimensions are equally mapped onto space.

  10. Phosphorus Imaging as a Tool for Studying the pH Metabolism in Living Insects

    NASA Astrophysics Data System (ADS)

    Skibbe, U.; Christeller, J. T.; Eccles, C. D.; Laing, W. A.; Callaghan, P. T.

    1995-09-01

    Comparative 31P NMR and 1H NMR imaging experiments at submillimeter pixel resolution were carried out, using a specially constructed solenoidal RF coil. Chemical-shift imaging is used to provide pH maps from the midgut of a Lepidopteran larvae and to demonstrate physiological dependence in the resulting images, The titration curve of pH versus chemical shift for inorganic phosphate is extended beyond the "normal" biological range to the strong alkaline limit.

  11. High capacity reversible watermarking for audio by histogram shifting and predicted error expansion.

    PubMed

    Wang, Fei; Xie, Zhaoxin; Chen, Zuo

    2014-01-01

    Being reversible, the watermarking information embedded in audio signals can be extracted while the original audio data can achieve lossless recovery. Currently, the few reversible audio watermarking algorithms are confronted with following problems: relatively low SNR (signal-to-noise) of embedded audio; a large amount of auxiliary embedded location information; and the absence of accurate capacity control capability. In this paper, we present a novel reversible audio watermarking scheme based on improved prediction error expansion and histogram shifting. First, we use differential evolution algorithm to optimize prediction coefficients and then apply prediction error expansion to output stego data. Second, in order to reduce location map bits length, we introduced histogram shifting scheme. Meanwhile, the prediction error modification threshold according to a given embedding capacity can be computed by our proposed scheme. Experiments show that this algorithm improves the SNR of embedded audio signals and embedding capacity, drastically reduces location map bits length, and enhances capacity control capability.

  12. Varieties of Quantity Estimation in Children

    ERIC Educational Resources Information Center

    Sella, Francesco; Berteletti, Ilaria; Lucangeli, Daniela; Zorzi, Marco

    2015-01-01

    In the number-to-position task, with increasing age and numerical expertise, children's pattern of estimates shifts from a biased (nonlinear) to a formal (linear) mapping. This widely replicated finding concerns symbolic numbers, whereas less is known about other types of quantity estimation. In Experiment 1, Preschool, Grade 1, and Grade 3…

  13. Selection in spatial working memory is independent of perceptual selective attention, but they interact in a shared spatial priority map.

    PubMed

    Hedge, Craig; Oberauer, Klaus; Leonards, Ute

    2015-11-01

    We examined the relationship between the attentional selection of perceptual information and of information in working memory (WM) through four experiments, using a spatial WM-updating task. Participants remembered the locations of two objects in a matrix and worked through a sequence of updating operations, each mentally shifting one dot to a new location according to an arrow cue. Repeatedly updating the same object in two successive steps is typically faster than switching to the other object; this object switch cost reflects the shifting of attention in WM. In Experiment 1, the arrows were presented in random peripheral locations, drawing perceptual attention away from the selected object in WM. This manipulation did not eliminate the object switch cost, indicating that the mechanisms of perceptual selection do not underlie selection in WM. Experiments 2a and 2b corroborated the independence of selection observed in Experiment 1, but showed a benefit to reaction times when the placement of the arrow cue was aligned with the locations of relevant objects in WM. Experiment 2c showed that the same benefit also occurs when participants are not able to mark an updating location through eye fixations. Together, these data can be accounted for by a framework in which perceptual selection and selection in WM are separate mechanisms that interact through a shared spatial priority map.

  14. Evolution of probability densities in stochastic coupled map lattices

    NASA Astrophysics Data System (ADS)

    Losson, Jérôme; Mackey, Michael C.

    1995-08-01

    This paper describes the statistical properties of coupled map lattices subjected to the influence of stochastic perturbations. The stochastic analog of the Perron-Frobenius operator is derived for various types of noise. When the local dynamics satisfy rather mild conditions, this equation is shown to possess either stable, steady state solutions (i.e., a stable invariant density) or density limit cycles. Convergence of the phase space densities to these limit cycle solutions explains the nonstationary behavior of statistical quantifiers at equilibrium. Numerical experiments performed on various lattices of tent, logistic, and shift maps with diffusivelike interelement couplings are examined in light of these theoretical results.

  15. Remote sensing image segmentation based on Hadoop cloud platform

    NASA Astrophysics Data System (ADS)

    Li, Jie; Zhu, Lingling; Cao, Fubin

    2018-01-01

    To solve the problem that the remote sensing image segmentation speed is slow and the real-time performance is poor, this paper studies the method of remote sensing image segmentation based on Hadoop platform. On the basis of analyzing the structural characteristics of Hadoop cloud platform and its component MapReduce programming, this paper proposes a method of image segmentation based on the combination of OpenCV and Hadoop cloud platform. Firstly, the MapReduce image processing model of Hadoop cloud platform is designed, the input and output of image are customized and the segmentation method of the data file is rewritten. Then the Mean Shift image segmentation algorithm is implemented. Finally, this paper makes a segmentation experiment on remote sensing image, and uses MATLAB to realize the Mean Shift image segmentation algorithm to compare the same image segmentation experiment. The experimental results show that under the premise of ensuring good effect, the segmentation rate of remote sensing image segmentation based on Hadoop cloud Platform has been greatly improved compared with the single MATLAB image segmentation, and there is a great improvement in the effectiveness of image segmentation.

  16. Semisupervised GDTW kernel-based fuzzy c-means algorithm for mapping vegetation dynamics in mining region using normalized difference vegetation index time series

    NASA Astrophysics Data System (ADS)

    Jia, Duo; Wang, Cangjiao; Lei, Shaogang

    2018-01-01

    Mapping vegetation dynamic types in mining areas is significant for revealing the mechanisms of environmental damage and for guiding ecological construction. Dynamic types of vegetation can be identified by applying interannual normalized difference vegetation index (NDVI) time series. However, phase differences and time shifts in interannual time series decrease mapping accuracy in mining regions. To overcome these problems and to increase the accuracy of mapping vegetation dynamics, an interannual Landsat time series for optimum vegetation growing status was constructed first by using the enhanced spatial and temporal adaptive reflectance fusion model algorithm. We then proposed a Markov random field optimized semisupervised Gaussian dynamic time warping kernel-based fuzzy c-means (FCM) cluster algorithm for interannual NDVI time series to map dynamic vegetation types in mining regions. The proposed algorithm has been tested in the Shengli mining region and Shendong mining region, which are typical representatives of China's open-pit and underground mining regions, respectively. Experiments show that the proposed algorithm can solve the problems of phase differences and time shifts to achieve better performance when mapping vegetation dynamic types. The overall accuracies for the Shengli and Shendong mining regions were 93.32% and 89.60%, respectively, with improvements of 7.32% and 25.84% when compared with the original semisupervised FCM algorithm.

  17. Fragment-based 13C nuclear magnetic resonance chemical shift predictions in molecular crystals: An alternative to planewave methods

    NASA Astrophysics Data System (ADS)

    Hartman, Joshua D.; Monaco, Stephen; Schatschneider, Bohdan; Beran, Gregory J. O.

    2015-09-01

    We assess the quality of fragment-based ab initio isotropic 13C chemical shift predictions for a collection of 25 molecular crystals with eight different density functionals. We explore the relative performance of cluster, two-body fragment, combined cluster/fragment, and the planewave gauge-including projector augmented wave (GIPAW) models relative to experiment. When electrostatic embedding is employed to capture many-body polarization effects, the simple and computationally inexpensive two-body fragment model predicts both isotropic 13C chemical shifts and the chemical shielding tensors as well as both cluster models and the GIPAW approach. Unlike the GIPAW approach, hybrid density functionals can be used readily in a fragment model, and all four hybrid functionals tested here (PBE0, B3LYP, B3PW91, and B97-2) predict chemical shifts in noticeably better agreement with experiment than the four generalized gradient approximation (GGA) functionals considered (PBE, OPBE, BLYP, and BP86). A set of recommended linear regression parameters for mapping between calculated chemical shieldings and observed chemical shifts are provided based on these benchmark calculations. Statistical cross-validation procedures are used to demonstrate the robustness of these fits.

  18. Fragment-based (13)C nuclear magnetic resonance chemical shift predictions in molecular crystals: An alternative to planewave methods.

    PubMed

    Hartman, Joshua D; Monaco, Stephen; Schatschneider, Bohdan; Beran, Gregory J O

    2015-09-14

    We assess the quality of fragment-based ab initio isotropic (13)C chemical shift predictions for a collection of 25 molecular crystals with eight different density functionals. We explore the relative performance of cluster, two-body fragment, combined cluster/fragment, and the planewave gauge-including projector augmented wave (GIPAW) models relative to experiment. When electrostatic embedding is employed to capture many-body polarization effects, the simple and computationally inexpensive two-body fragment model predicts both isotropic (13)C chemical shifts and the chemical shielding tensors as well as both cluster models and the GIPAW approach. Unlike the GIPAW approach, hybrid density functionals can be used readily in a fragment model, and all four hybrid functionals tested here (PBE0, B3LYP, B3PW91, and B97-2) predict chemical shifts in noticeably better agreement with experiment than the four generalized gradient approximation (GGA) functionals considered (PBE, OPBE, BLYP, and BP86). A set of recommended linear regression parameters for mapping between calculated chemical shieldings and observed chemical shifts are provided based on these benchmark calculations. Statistical cross-validation procedures are used to demonstrate the robustness of these fits.

  19. Aerial images visual localization on a vector map using color-texture segmentation

    NASA Astrophysics Data System (ADS)

    Kunina, I. A.; Teplyakov, L. M.; Gladkov, A. P.; Khanipov, T. M.; Nikolaev, D. P.

    2018-04-01

    In this paper we study the problem of combining UAV obtained optical data and a coastal vector map in absence of satellite navigation data. The method is based on presenting the territory as a set of segments produced by color-texture image segmentation. We then find such geometric transform which gives the best match between these segments and land and water areas of the georeferenced vector map. We calculate transform consisting of an arbitrary shift relatively to the vector map and bound rotation and scaling. These parameters are estimated using the RANSAC algorithm which matches the segments contours and the contours of land and water areas of the vector map. To implement this matching we suggest computing shape descriptors robust to rotation and scaling. We performed numerical experiments demonstrating the practical applicability of the proposed method.

  20. A physiological frequency-position map of the chinchilla cochlea.

    PubMed

    Müller, Marcus; Hoidis, Silvi; Smolders, Jean W T

    2010-09-01

    Accumulating evidence indicates that mammalian cochlear frequency-position maps (location of maximum vibration of the basilar membrane as a function of frequency) depend on the physiological condition of the inner ear. Cochlear damage desensitizes the ear, after the damage the original location of maximum vibration is tuned to a lower sound frequency. This suggests that frequency-position maps, derived from such desensitized ears, are shifted to lower frequencies, corresponding to a shift of the basilar membrane vibration pattern towards the base for a given stimulus frequency. To test this hypothesis, we re-mapped the cochlear frequency-position map in the chinchilla. We collected frequency-position data from chinchillas in normal physiological condition ("physiological map") and compared these to data previously established from sound overexposed ears ("anatomical map"). The characteristic frequency (CF) of neurons in the cochlear nucleus was determined. Horse-radish peroxidase (HRP) or biocytin (BCT) were injected iontophoretically to trace auditory nerve fibers towards their innervation site in the organ of Corti. The relationship between distance from the base (d, percent) and frequency (f, kHz) was described best by a simple exponential function: d = 61.2 - 42.2 x log(f). The slope of the function was 2.55 mm/octave. Compared to the "anatomical map", the "physiological map" was shifted by about 0.3 octaves to higher frequencies corresponding to a shift of the basilar membrane vibration pattern of 0.8 mm towards the apex for a given stimulus frequency. Our findings affirm that frequency-position maps in the mammalian cochlea depend on the condition of the inner ear. Damage-induced desensitization in mammalian inner ears results in similar shifts of CF (about 0.5 octaves) but different shifts of the maximum of the vibration pattern towards the base at given frequencies, dependent on the mapping constant of the species, longer basilar membranes showing a larger basal shift. Furthermore, the results substantiate the notion that "crowding" at lower frequencies appears to be a specialization rather than a general feature. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  1. Nonlinearity response correction in phase-shifting deflectometry

    NASA Astrophysics Data System (ADS)

    Nguyen, Manh The; Kang, Pilseong; Ghim, Young-Sik; Rhee, Hyug-Gyo

    2018-04-01

    Owing to the nonlinearity response of digital devices such as screens and cameras in phase-shifting deflectometry, non-sinusoidal phase-shifted fringe patterns are generated and additional measurement errors are introduced. In this paper, a new deflectometry technique is described for overcoming these problems using a pre-distorted pattern combined with an advanced iterative algorithm. The experiment results show that this method can reconstruct the 3D surface map of a sample without fringe print-through caused by the nonlinearity response of digital devices. The proposed technique is verified by measuring the surface height variations in a deformable mirror and comparing them with the measurement result obtained using a coordinate measuring machine. The difference between the two measurement results is estimated to be less than 13 µm.

  2. Rapid resetting of rabbit aortic baroreceptors and reflex heart rate responses by directional changes in blood pressure.

    PubMed

    Burke, S L; Dorward, P K; Korner, P I

    1986-09-01

    In both anaesthetized and conscious rabbits, perivascular balloon inflations slowly raised or lowered mean arterial pressure (M.A.P.), at 1-2 mmHg/s, from resting to various plateau pressures. Deflations then returned the M.A.P. to resting. 'Steady-state' curves relating M.A.P. to unitary aortic baroreceptor firing, integrated aortic nerve activity and heart rate were derived during the primary and return pressure changes and they formed typical hysteresis loops. In single units, return M.A.P.-frequency curves were shifted in the same direction as the primary pressure changes by an average 0.37 mmHg per mmHg change in M.A.P. Shifts were linearly related to the changes in M.A.P. between resting and plateau levels for all pressure rises and for falls less than 30 mmHg. They were established within 30 s and were quantitatively similar to the rapid resetting of baroreceptor function curves found 15 min-2 h after a change in resting M.A.P. (Dorward, Andresen, Burke, Oliver & Korner, 1982). Unit threshold pressures were shifted within 20 s to the same extent as the over-all curve shift to which they contributed. In the whole aortic nerve, return M.A.P.-integrated activity curves were shifted to same degree as unit function curves in both anaesthetized and conscious rabbits. Simultaneous shifts of return reflex M.A.P.-heart rate curves were also seen in conscious rabbits within 30 s. During M.A.P. falls, receptor and reflex hysteresis was similar, but during M.A.P. rises, reflex shifts were double baroreceptor shifts, suggesting the involvement of other pressure-sensitive receptors. We conclude that hysteresis shifts in baroreceptor function curves, which follow the reversal of slow ramp changes in blood pressure are a form of rapid resetting. They are accompanied by rapid resetting of reflex heart rate responses. We regard this as an important mechanism in blood pressure control which produces relatively high-gain reflex responses, during slow directional pressure changes, over a wider range of absolute pressure levels than would otherwise be possible.

  3. A High Resolution Phase Shifting Interferometer.

    NASA Astrophysics Data System (ADS)

    Bayda, Michael; Bartscher, Christoph; Wilkinson, Allen

    1997-03-01

    Configuration, operation, and performance details of a high resolution phase shifting Twyman-Green interferometer are presented. The instrument was used for density relaxation experiments of very compressible liquid-vapor critical fluids.(A companion talk in the Nonequilibrium Phenomena session under Complex Fluids presents density equilibration work.) A sample assembly contained the cell, beam splitter, phase shifter, and mirrors inside a 6 cm diameter by 6 cm long aluminum cylinder. This sample assembly was contained inside a thermostat stable to 50 μK RMS deviation. A thin phase retarding Liquid Crystal Cell (LCC) was placed in the reference arm of the interferometer. The LCC provided four cumulative 90 degree phase shifts to produce four images used in computing each phase map. The Carré technique was used to calculate a phase value for each pixel from the four intensities of each pixel. Four images for one phase map could be acquired in less than two seconds. The spatial resolution was 25 μm. The phase resolution of the interferometer in a six second period was better than λ/400. The phase stability of the interferometer during 25 hours was better than λ/70. Factors affecting timing, resolution, and other phase shifting devices will be discussed. WWW Presentation

  4. A visual salience map in the primate frontal eye field.

    PubMed

    Thompson, Kirk G; Bichot, Narcisse P

    2005-01-01

    Models of attention and saccade target selection propose that within the brain there is a topographic map of visual salience that combines bottom-up and top-down influences to identify locations for further processing. The results of a series of experiments with monkeys performing visual search tasks have identified a population of frontal eye field (FEF) visually responsive neurons that exhibit all of the characteristics of a visual salience map. The activity of these FEF neurons is not sensitive to specific features of visual stimuli; but instead, their activity evolves over time to select the target of the search array. This selective activation reflects both the bottom-up intrinsic conspicuousness of the stimuli and the top-down knowledge and goals of the viewer. The peak response within FEF specifies the target for the overt gaze shift. However, the selective activity in FEF is not in itself a motor command because the magnitude of activation reflects the relative behavioral significance of the different stimuli in the visual scene and occurs even when no saccade is made. Identifying a visual salience map in FEF validates the theoretical concept of a salience map in many models of attention. In addition, it strengthens the emerging view that FEF is not only involved in producing overt gaze shifts, but is also important for directing covert spatial attention.

  5. Log-polar mapping-based scale space tracking with adaptive target response

    NASA Astrophysics Data System (ADS)

    Li, Dongdong; Wen, Gongjian; Kuai, Yangliu; Zhang, Ximing

    2017-05-01

    Correlation filter-based tracking has exhibited impressive robustness and accuracy in recent years. Standard correlation filter-based trackers are restricted to translation estimation and equipped with fixed target response. These trackers produce an inferior performance when encountered with a significant scale variation or appearance change. We propose a log-polar mapping-based scale space tracker with an adaptive target response. This tracker transforms the scale variation of the target in the Cartesian space into a shift along the logarithmic axis in the log-polar space. A one-dimensional scale correlation filter is learned online to estimate the shift along the logarithmic axis. With the log-polar representation, scale estimation is achieved accurately without a multiresolution pyramid. To achieve an adaptive target response, a variance of the Gaussian function is computed from the response map and updated online with a learning rate parameter. Our log-polar mapping-based scale correlation filter and adaptive target response can be combined with any correlation filter-based trackers. In addition, the scale correlation filter can be extended to a two-dimensional correlation filter to achieve joint estimation of the scale variation and in-plane rotation. Experiments performed on an OTB50 benchmark demonstrate that our tracker achieves superior performance against state-of-the-art trackers.

  6. Dynamics of Stability of Orientation Maps Recorded with Optical Imaging.

    PubMed

    Shumikhina, S I; Bondar, I V; Svinov, M M

    2018-03-15

    Orientation selectivity is an important feature of visual cortical neurons. Optical imaging of the visual cortex allows for the generation of maps of orientation selectivity that reflect the activity of large populations of neurons. To estimate the statistical significance of effects of experimental manipulations, evaluation of the stability of cortical maps over time is required. Here, we performed optical imaging recordings of the visual cortex of anesthetized adult cats. Monocular stimulation with moving clockwise square-wave gratings that continuously changed orientation and direction was used as the mapping stimulus. Recordings were repeated at various time intervals, from 15 min to 16 h. Quantification of map stability was performed on a pixel-by-pixel basis using several techniques. Map reproducibility showed clear dynamics over time. The highest degree of stability was seen in maps recorded 15-45 min apart. Averaging across all time intervals and all stimulus orientations revealed a mean shift of 2.2 ± 0.1°. There was a significant tendency for larger shifts to occur at longer time intervals. Shifts between 2.8° (mean ± 2SD) and 5° were observed more frequently at oblique orientations, while shifts greater than 5° appeared more frequently at cardinal orientations. Shifts greater than 5° occurred rarely overall (5.4% of cases) and never exceeded 11°. Shifts of 10-10.6° (0.7%) were seen occasionally at time intervals of more than 4 h. Our findings should be considered when evaluating the potential effect of experimental manipulations on orientation selectivity mapping studies. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.

  7. Three-step interferometric method with blind phase shifts by use of interframe correlation between interferograms

    NASA Astrophysics Data System (ADS)

    Muravsky, Leonid I.; Kmet', Arkady B.; Stasyshyn, Ihor V.; Voronyak, Taras I.; Bobitski, Yaroslav V.

    2018-06-01

    A new three-step interferometric method with blind phase shifts to retrieve phase maps (PMs) of smooth and low-roughness engineering surfaces is proposed. Evaluating of two unknown phase shifts is fulfilled by using the interframe correlation between interferograms. The method consists of two stages. The first stage provides recording of three interferograms of a test object and their processing including calculation of unknown phase shifts, and retrieval of a coarse PM. The second stage implements firstly separation of high-frequency and low-frequency PMs and secondly producing of a fine PM consisting of areal surface roughness and waviness PMs. Extraction of the areal surface roughness and waviness PMs is fulfilled by using a linear low-pass filter. The computer simulation and experiments fulfilled to retrieve a gauge block surface area and its areal surface roughness and waviness have confirmed the reliability of the proposed three-step method.

  8. Fragment-based {sup 13}C nuclear magnetic resonance chemical shift predictions in molecular crystals: An alternative to planewave methods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hartman, Joshua D.; Beran, Gregory J. O., E-mail: gregory.beran@ucr.edu; Monaco, Stephen

    2015-09-14

    We assess the quality of fragment-based ab initio isotropic {sup 13}C chemical shift predictions for a collection of 25 molecular crystals with eight different density functionals. We explore the relative performance of cluster, two-body fragment, combined cluster/fragment, and the planewave gauge-including projector augmented wave (GIPAW) models relative to experiment. When electrostatic embedding is employed to capture many-body polarization effects, the simple and computationally inexpensive two-body fragment model predicts both isotropic {sup 13}C chemical shifts and the chemical shielding tensors as well as both cluster models and the GIPAW approach. Unlike the GIPAW approach, hybrid density functionals can be used readilymore » in a fragment model, and all four hybrid functionals tested here (PBE0, B3LYP, B3PW91, and B97-2) predict chemical shifts in noticeably better agreement with experiment than the four generalized gradient approximation (GGA) functionals considered (PBE, OPBE, BLYP, and BP86). A set of recommended linear regression parameters for mapping between calculated chemical shieldings and observed chemical shifts are provided based on these benchmark calculations. Statistical cross-validation procedures are used to demonstrate the robustness of these fits.« less

  9. Distortion correction in EPI at ultra-high-field MRI using PSF mapping with optimal combination of shift detection dimension.

    PubMed

    Oh, Se-Hong; Chung, Jun-Young; In, Myung-Ho; Zaitsev, Maxim; Kim, Young-Bo; Speck, Oliver; Cho, Zang-Hee

    2012-10-01

    Despite its wide use, echo-planar imaging (EPI) suffers from geometric distortions due to off-resonance effects, i.e., strong magnetic field inhomogeneity and susceptibility. This article reports a novel method for correcting the distortions observed in EPI acquired at ultra-high-field such as 7 T. Point spread function (PSF) mapping methods have been proposed for correcting the distortions in EPI. The PSF shift map can be derived either along the nondistorted or the distorted coordinates. Along the nondistorted coordinates more information about compressed areas is present but it is prone to PSF-ghosting artifacts induced by large k-space shift in PSF encoding direction. In contrast, shift maps along the distorted coordinates contain more information in stretched areas and are more robust against PSF-ghosting. In ultra-high-field MRI, an EPI contains both compressed and stretched regions depending on the B0 field inhomogeneity and local susceptibility. In this study, we present a new geometric distortion correction scheme, which selectively applies the shift map with more information content. We propose a PSF-ghost elimination method to generate an artifact-free pixel shift map along nondistorted coordinates. The proposed method can correct the effects of the local magnetic field inhomogeneity induced by the susceptibility effects along with the PSF-ghost artifact cancellation. We have experimentally demonstrated the advantages of the proposed method in EPI data acquisitions in phantom and human brain using 7-T MRI. Copyright © 2011 Wiley Periodicals, Inc.

  10. Response Selection Difficulty and Asymmetrical Costs of Switching Between Tasks and Stimuli: No Evidence for an Exogenous Component of Task-Set Reconfiguration

    ERIC Educational Resources Information Center

    Hubner, Mike; Kluwe, Rainer H.; Luna-Rodriguez, Aquiles; Peters, Alexandra

    2004-01-01

    Four task-switching experiments examined the notion of an exogenous component of task-set reconfiguration (i.e., a process needed to shift task set that is not initiated in the absence of a task-associated figuration stimulus). The authors varied the complexity and familiarity of stimulus-response (SR) mapping rules to produce differentially…

  11. Combined passive acoustic mapping and magnetic resonance thermometry for monitoring phase-shift nanoemulsion enhanced focused ultrasound therapy

    NASA Astrophysics Data System (ADS)

    Crake, Calum; Meral, F. Can; Burgess, Mark T.; Papademetriou, Iason T.; McDannold, Nathan J.; Porter, Tyrone M.

    2017-08-01

    Focused ultrasound (FUS) has the potential to enable precise, image-guided noninvasive surgery for the treatment of cancer in which tumors are identified and destroyed in a single integrated procedure. However, success of the method in highly vascular organs has been limited due to heat losses to perfusion, requiring development of techniques to locally enhance energy absorption and heating. In addition, FUS procedures are conventionally monitored using MRI, which provides excellent anatomical images and can map temperature, but is not capable of capturing the full gamut of available data such as the acoustic emissions generated during this inherently acoustically-driven procedure. Here, we employed phase-shift nanoemulsions (PSNE) embedded in tissue phantoms to promote cavitation and hence temperature rise induced by FUS. In addition, we incorporated passive acoustic mapping (PAM) alongside simultaneous MR thermometry in order to visualize both acoustic emissions and temperature rise, within the bore of a full scale clinical MRI scanner. Focal cavitation of PSNE could be resolved using PAM and resulted in accelerated heating and increased the maximum elevated temperature measured via MR thermometry compared to experiments without nanoemulsions. Over time, the simultaneously acquired acoustic and temperature maps show translation of the focus of activity towards the FUS transducer, and the magnitude of the increase in cavitation and focal shift both increased with nanoemulsion concentration. PAM results were well correlated with MRI thermometry and demonstrated greater sensitivity, with the ability to detect cavitation before enhanced heating was observed. The results suggest that PSNE could be beneficial for enhancement of thermal focused ultrasound therapies and that PAM could be a critical tool for monitoring this process.

  12. Orientation in birds. The sun compass.

    PubMed

    Schmidt-Koenig, K; Ganzhorn, J U; Ranvaud, R

    1991-01-01

    The sun compass was discovered by G. Kramer in caged birds showing migratory restlessness. Subsequent experiments with caged birds employing directional training and clock shifts, carried out by Hoffman and Schmidt-Koenig, showed that the sun azimuth is used, and the sun altitude ignored. In the laboratory, McDonald found the accuracy to be +/- 3 degrees(-)+/- 5 degrees. According to Hoffmann and Schmidt-Koenig, caged birds trained at medium northern latitudes were able to allow for the sun's apparent movement north of the arctic circle, but not in equatorial and trans-equatorial latitudes. In homing experiments, and employing clock shifts, Schmidt-Koenig demonstrated that the sun compass is used by homing pigeons during initial orientation. This finding is the principal evidence for the existence of a map-and-compass navigational system. Pigeons living in equatorial latitudes utilize the sun compass even under the extreme solar conditions of equinox, achieving angular resolution of about 3 degrees in homing experiments. According to preliminary analyses, the homing pigeons' ephemerides are retarded by several weeks (Ranvaud, Schmidt-Koenig, Ganzhorn et al.).

  13. Plasticity of orientation preference maps in the visual cortex of adult cats.

    PubMed

    Godde, Ben; Leonhardt, Ralph; Cords, Sven M; Dinse, Hubert R

    2002-04-30

    In contrast to the high degree of experience-dependent plasticity usually exhibited by cortical representational maps, a number of experiments performed in visual cortex suggest that the basic layout of orientation preference maps is only barely susceptible to activity-dependent modifications. In fact, most of what we know about activity-dependent plasticity in adults comes from experiments in somatosensory, auditory, or motor cortex. Applying a stimulation protocol that has been proven highly effective in other cortical areas, we demonstrate here that enforced synchronous cortical activity induces major changes of orientation preference maps (OPMs) in adult cats. Combining optical imaging of intrinsic signals and electrophysiological single-cell recordings, we show that a few hours of intracortical microstimulation (ICMS) lead to an enlargement of the cortical representational zone at the ICMS site and an extensive restructuring of the entire OPM layout up to several millimeters away, paralleled by dramatic changes of pinwheel numbers and locations. At the single-cell level, we found that the preferred orientation was shifted toward the orientation of the ICMS site over a region of up to 4 mm. Our results show that manipulating the synchronicity of cortical activity locally without invoking training, attention, or reinforcement, OPMs undergo large-scale reorganization reminiscent of plastic changes observed for nonvisual cortical maps. However, changes were much more widespread and enduring. Such large-scale restructuring of the visual cortical networks indicates a substantial capability for activity-dependent plasticity of adult visual cortex and may provide the basis for cognitive learning processes.

  14. Problem of intraoperative anatomical shift in image-guided surgery

    NASA Astrophysics Data System (ADS)

    Nauta, Haring J.; Bonnen, J. G.

    1998-06-01

    Experience with image guided, frameless stereotactic neurosurgery shows that intraoperative brain position shifts can be large enough to be problematic, and can occur in different directions at different directions at different stages of an operation. An understanding of the behavior of shifts will allow the surgeon to make the most appropriate use of the image guidance by first minimizing the shift itself, and then anticipating and compensating for any influence the remaining shift will have on the accuracy of the guidance. Three types of shift are described. Type I shift is a local outward bulging that occurs after the skull and dura are opened but before a mass lesion is resected. Type II shift is a local collapse of the brain tissue into the space previously occupied by the tumor. Type III shift is related to loss of cerebrospinal fluid or brain dehydration and is a generalized, more symmetric loss of brain volume. Strategies to minimize these types of shift include appropriate use of medical measures to reduce brain swelling early in the procedure without producing so much brain dehydration that Type II shift is accentuated later in the procedure. Other strategies include mechanical stabilization of brain position with retractors. Anticipating shift, the neurosurgeon should use the guidance as far as possible to map key boundaries early in the procedure before shift becomes more pronounced. Ultimately, however, the correction for the problem of intraoperative brain shift will require the ability to update the imaging data during the surgery.

  15. Taking Place and Mapping Space: How Pre-Service Art Education Students' Visual Narratives of Field Experiences in Urban/Inner-City Schools Reveal a Spatial Knowing of Place

    ERIC Educational Resources Information Center

    Sutters, Justin Peter

    2012-01-01

    This doctoral study concerns itself with how primarily White, suburban, middle-class Art Education pre-service students are prepared in academia to teach in urban/inner-city schools. As a researcher, student-teaching supervisor, Cooperating teacher, and public school Art Educator, the author examines the shifting demographics of public education…

  16. Electrophysiological correlates of preparation and implementation for different types of task shifts.

    PubMed

    Hsieh, Shulan; Wu, Mengyao

    2011-11-14

    The ability to flexibly shift between tasks is central to cognitive control, but whether the same brain mechanisms mediate shifting across different tasks is unknown. In this study, we investigated whether variations in stimulus-dimensions or response-mapping might influence task switching in terms of its preparatory processes, as reflected in cue-locked event-related potentials (ERPs), and its implementation processes, as reflected in stimulus-locked ERPs. Participants judged pairs of digits as same or different in one of two conditions. In one condition, the task-relevant stimulus-dimension was either repeated or switched across trials while the response-mapping rule was kept constant. In the other condition, the task-relevant stimulus-dimension was kept constant while the response-mapping rule was repeated or switched across trials. The length of the preparatory interval was manipulated. Data revealed switch-related preparatory ERP components (including N2 and a late slow positivity) that were associated with both types of task shifting and an N400-like negativity that distinguished between the two types. Several switch-related implementation ERP components associated with both types of task shifting were found at posterior sites. Distinct frontal modulations of the N1, P2, and N2 were found to associate with the implementation of the response-mapping shift, whereas a slow positivity was associated with the implementation of the stimulus-dimension shift. Therefore, this study demonstrates that there are shared and distinct processes across different types of task shifting. Finally, because the same transition-cue was used for different task shifts, the distinct processes cannot be explained simply by differences in cue processing. Copyright © 2011 Elsevier B.V. All rights reserved.

  17. Combining automated peak tracking in SAR by NMR with structure-based backbone assignment from 15N-NOESY

    PubMed Central

    2012-01-01

    Background Chemical shift mapping is an important technique in NMR-based drug screening for identifying the atoms of a target protein that potentially bind to a drug molecule upon the molecule's introduction in increasing concentrations. The goal is to obtain a mapping of peaks with known residue assignment from the reference spectrum of the unbound protein to peaks with unknown assignment in the target spectrum of the bound protein. Although a series of perturbed spectra help to trace a path from reference peaks to target peaks, a one-to-one mapping generally is not possible, especially for large proteins, due to errors, such as noise peaks, missing peaks, missing but then reappearing, overlapped, and new peaks not associated with any peaks in the reference. Due to these difficulties, the mapping is typically done manually or semi-automatically, which is not efficient for high-throughput drug screening. Results We present PeakWalker, a novel peak walking algorithm for fast-exchange systems that models the errors explicitly and performs many-to-one mapping. On the proteins: hBclXL, UbcH5B, and histone H1, it achieves an average accuracy of over 95% with less than 1.5 residues predicted per target peak. Given these mappings as input, we present PeakAssigner, a novel combined structure-based backbone resonance and NOE assignment algorithm that uses just 15N-NOESY, while avoiding TOCSY experiments and 13C-labeling, to resolve the ambiguities for a one-to-one mapping. On the three proteins, it achieves an average accuracy of 94% or better. Conclusions Our mathematical programming approach for modeling chemical shift mapping as a graph problem, while modeling the errors directly, is potentially a time- and cost-effective first step for high-throughput drug screening based on limited NMR data and homologous 3D structures. PMID:22536902

  18. Two-dimensional strain-mapping by electron backscatter diffraction and confocal Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Gayle, Andrew J.; Friedman, Lawrence H.; Beams, Ryan; Bush, Brian G.; Gerbig, Yvonne B.; Michaels, Chris A.; Vaudin, Mark D.; Cook, Robert F.

    2017-11-01

    The strain field surrounding a spherical indentation in silicon is mapped in two dimensions (2-D) using electron backscatter diffraction (EBSD) cross-correlation and confocal Raman spectroscopy techniques. The 200 mN indentation created a 4 μm diameter residual contact impression in the silicon (001) surface. Maps about 50 μm × 50 μm area with 128 pixels × 128 pixels were generated in several hours, extending, by comparison, assessment of the accuracy of both techniques to mapping multiaxial strain states in 2-D. EBSD measurements showed a residual strain field dominated by in-surface normal and shear strains, with alternating tensile and compressive lobes extending about three to four indentation diameters from the contact and exhibiting two-fold symmetry. Raman measurements showed a residual Raman shift field, dominated by positive shifts, also extending about three to four indentation diameters from the contact but exhibiting four-fold symmetry. The 2-D EBSD results, in combination with a mechanical-spectroscopic analysis, were used to successfully predict the 2-D Raman shift map in scale, symmetry, and shift magnitude. Both techniques should be useful in enhancing the reliability of microelectromechanical systems (MEMS) through identification of the 2-D strain fields in MEMS devices.

  19. Spatially varying density dependence drives a shifting mosaic of survival in a recovering apex predator (Canis lupus).

    PubMed

    O'Neil, Shawn T; Bump, Joseph K; Beyer, Dean E

    2017-11-01

    Understanding landscape patterns in mortality risk is crucial for promoting recovery of threatened and endangered species. Humans affect mortality risk in large carnivores such as wolves ( Canis lupus ), but spatiotemporally varying density dependence can significantly influence the landscape of survival. This potentially occurs when density varies spatially and risk is unevenly distributed. We quantified spatiotemporal sources of variation in survival rates of gray wolves ( C. lupus ) during a 21-year period of population recovery in the Upper Peninsula of Michigan, USA. We focused on mapping risk across time using Cox Proportional Hazards (CPH) models with time-dependent covariates, thus exploring a shifting mosaic of survival. Extended CPH models and time-dependent covariates revealed influences of seasonality, density dependence and experience, as well as individual-level factors and landscape predictors of risk. We used results to predict the shifting landscape of risk at the beginning, middle, and end of the wolf recovery time series. Survival rates varied spatially and declined over time. Long-term change was density-dependent, with landscape predictors such as agricultural land cover and edge densities contributing negatively to survival. Survival also varied seasonally and depended on individual experience, sex, and resident versus transient status. The shifting landscape of survival suggested that increasing density contributed to greater potential for human conflict and wolf mortality risk. Long-term spatial variation in key population vital rates is largely unquantified in many threatened, endangered, and recovering species. Variation in risk may indicate potential for source-sink population dynamics, especially where individuals preemptively occupy suitable territories, which forces new individuals into riskier habitat types as density increases. We encourage managers to explore relationships between adult survival and localized changes in population density. Density-dependent risk maps can identify increasing conflict areas or potential habitat sinks which may persist due to high recruitment in adjacent habitats.

  20. Factors reducing the expected deflection in initial orientation in clock-shifted homing pigeons.

    PubMed

    Gagliardo, Anna; Odetti, Francesca; Ioalè, Paolo

    2005-02-01

    To orient from familiar sites, homing pigeons can rely on both an olfactory map and visual familiar landmarks. The latter can in principle be used in two different ways: either within a topographical map exploited for piloting or in a so-called mosaic map associated with a compass bearing. One way to investigate the matter is to put the compass and the topographical information in conflict by releasing clock-shifted pigeons from familiar locations. Although the compass orientation is in general dominant over a piloting strategy, a stronger or weaker tendency to correct towards the home direction by clock-shifted pigeons released from very familiar sites has often been observed. To investigate which factors are involved in the reduction of the deviation due to clock-shift, we performed a series of releases with intact and anosmic pigeons from familiar sites in unshifted and clock-shifted conditions and a series of releases from the same sites with naive clock-shifted birds. Our data suggest that the following factors have a role in reducing deviation due to the clock-shift: familiarity with the release site, the lack of olfactory information and some unknown site-dependent features.

  1. Language-Mediated Visual Orienting Behavior in Low and High Literates

    PubMed Central

    Huettig, Falk; Singh, Niharika; Mishra, Ramesh Kumar

    2011-01-01

    The influence of formal literacy on spoken language-mediated visual orienting was investigated by using a simple look and listen task which resembles every day behavior. In Experiment 1, high and low literates listened to spoken sentences containing a target word (e.g., “magar,” crocodile) while at the same time looking at a visual display of four objects (a phonological competitor of the target word, e.g., “matar,” peas; a semantic competitor, e.g., “kachuwa,” turtle, and two unrelated distractors). In Experiment 2 the semantic competitor was replaced with another unrelated distractor. Both groups of participants shifted their eye gaze to the semantic competitors (Experiment 1). In both experiments high literates shifted their eye gaze toward phonological competitors as soon as phonological information became available and moved their eyes away as soon as the acoustic information mismatched. Low literates in contrast only used phonological information when semantic matches between spoken word and visual referent were not present (Experiment 2) but in contrast to high literates these phonologically mediated shifts in eye gaze were not closely time-locked to the speech input. These data provide further evidence that in high literates language-mediated shifts in overt attention are co-determined by the type of information in the visual environment, the timing of cascaded processing in the word- and object-recognition systems, and the temporal unfolding of the spoken language. Our findings indicate that low literates exhibit a similar cognitive behavior but instead of participating in a tug-of-war among multiple types of cognitive representations, word–object mapping is achieved primarily at the semantic level. If forced, for instance by a situation in which semantic matches are not present (Experiment 2), low literates may on occasion have to rely on phonological information but do so in a much less proficient manner than their highly literate counterparts. PMID:22059083

  2. Observation of FeGe skyrmions by electron phase microscopy with hole-free phase plate

    NASA Astrophysics Data System (ADS)

    Kotani, Atsuhiro; Harada, Ken; Malac, Marek; Salomons, Mark; Hayashida, Misa; Mori, Shigeo

    2018-05-01

    We report application of hole-free phase plate (HFPP) to imaging of magnetic skyrmion lattices. Using HFPP imaging, we observed skyrmions in FeGe, and succeeded in obtaining phase contrast images that reflect the sample magnetization distribution. According to the Aharonov-Bohm effect, the electron phase is shifted by the magnetic flux due to sample magnetization. The differential processing of the intensity in a HFPP image allows us to successfully reconstruct the magnetization map of the skyrmion lattice. Furthermore, the calculated phase shift due to the magnetization of the thin film was consistent with that measured by electron holography experiment, which demonstrates that HFPP imaging can be utilized for analysis of magnetic fields and electrostatic potential distribution at the nanoscale.

  3. Projected climate impacts for the amphibians of the western hemisphere

    USGS Publications Warehouse

    Lawler, Joshua J.; Shafer, Sarah L.; Bancroft, Betsy A.; Blaustein, Andrew R.

    2010-01-01

    Given their physiological requirements, limited dispersal abilities, and hydrologically sensitive habitats, amphibians are likely to be highly sensitive to future climatic changes. We used three approaches to map areas in the western hemisphere where amphibians are particularly likely to be affected by climate change. First, we used bioclimatic models to project potential climate-driven shifts in the distribution of 413 amphibian species based on 20 climate simulations for 2071–2100. We summarized these projections to produce estimates of species turnover. Second, we mapped the distribution of 1099 species with restricted geographic ranges. Finally, using the 20 future climate-change simulations, we mapped areas that were consistently projected to receive less seasonal precipitation in the coming century and thus were likely to have altered microclimates and local hydrologies. Species turnover was projected to be highest in the Andes Mountains and parts of Central America and Mexico, where, on average, turnover rates exceeded 60% under the lower of two emissions scenarios. Many of the restricted-range species not included in our range-shift analyses were concentrated in parts of the Andes and Central America and in Brazil's Atlantic Forest. Much of Central America, southwestern North America, and parts of South America were consistently projected to experience decreased precipitation by the end of the century. Combining the results of the three analyses highlighted several areas in which amphibians are likely to be significantly affected by climate change for multiple reasons. Portions of southern Central America were simultaneously projected to experience high species turnover, have many additional restricted-range species, and were consistently projected to receive less precipitation. Together, our three analyses form one potential assessment of the geographic vulnerability of amphibians to climate change and as such provide broad-scale guidance for directing conservation efforts.

  4. Projected climate impacts for the amphibians of the Western hemisphere.

    PubMed

    Lawler, Joshua J; Shafer, Sarah L; Bancroft, Betsy A; Blaustein, Andrew R

    2010-02-01

    Given their physiological requirements, limited dispersal abilities, and hydrologically sensitive habitats, amphibians are likely to be highly sensitive to future climatic changes. We used three approaches to map areas in the western hemisphere where amphibians are particularly likely to be affected by climate change. First, we used bioclimatic models to project potential climate-driven shifts in the distribution of 413 amphibian species based on 20 climate simulations for 2071-2100. We summarized these projections to produce estimates of species turnover. Second, we mapped the distribution of 1099 species with restricted geographic ranges. Finally, using the 20 future climate-change simulations, we mapped areas that were consistently projected to receive less seasonal precipitation in the coming century and thus were likely to have altered microclimates and local hydrologies. Species turnover was projected to be highest in the Andes Mountains and parts of Central America and Mexico, where, on average, turnover rates exceeded 60% under the lower of two emissions scenarios. Many of the restricted-range species not included in our range-shift analyses were concentrated in parts of the Andes and Central America and in Brazil's Atlantic Forest. Much of Central America, southwestern North America, and parts of South America were consistently projected to experience decreased precipitation by the end of the century. Combining the results of the three analyses highlighted several areas in which amphibians are likely to be significantly affected by climate change for multiple reasons. Portions of southern Central America were simultaneously projected to experience high species turnover, have many additional restricted-range species, and were consistently projected to receive less precipitation. Together, our three analyses form one potential assessment of the geographic vulnerability of amphibians to climate change and as such provide broad-scale guidance for directing conservation efforts.

  5. A note on chaotic unimodal maps and applications.

    PubMed

    Zhou, C T; He, X T; Yu, M Y; Chew, L Y; Wang, X G

    2006-09-01

    Based on the word-lift technique of symbolic dynamics of one-dimensional unimodal maps, we investigate the relation between chaotic kneading sequences and linear maximum-length shift-register sequences. Theoretical and numerical evidence that the set of the maximum-length shift-register sequences is a subset of the set of the universal sequence of one-dimensional chaotic unimodal maps is given. By stabilizing unstable periodic orbits on superstable periodic orbits, we also develop techniques to control the generation of long binary sequences.

  6. Spatial phase-shift dual-beam speckle interferometry.

    PubMed

    Gao, Xinya; Yang, Lianxiang; Wang, Yonghong; Zhang, Boyang; Dan, Xizuo; Li, Junrui; Wu, Sijin

    2018-01-20

    The spatial phase-shift technique has been successfully applied to an out-of-plane speckle interferometry system. Its application to a pure in-plane sensitive system has not been reported yet. This paper presents a novel optical configuration that enables the application of the spatial phase-shift technique to pure in-plane sensitive dual-beam speckle interferometry. The new spatial phase-shift dual-beam speckle interferometry (SPS-DBSP) uses a dual-beam in-plane electronic speckle pattern interferometry configuration with individual aperture shears, avoiding the interference in the object plane by the use of a low-coherence source, and different optical paths. The measured object is illuminated by two incoherent beams that are generated by a delay line, which is larger than the coherence length of the laser. The two beams reflected from the object surface interfere with each other at the CCD plane because of different optical paths. A spatial phase shift is introduced by the angle between the two apertures when they are mapped to the same optical axis. The phase of the in-plane deformation can directly be extracted from the speckle patterns by the Fourier transform method. The capability of SPS-DBSI is demonstrated by theoretical discussion as well as experiments.

  7. Averaged kick maps: less noise, more signal…and probably less bias

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pražnikar, Jure; Afonine, Pavel V.; Gunčar, Gregor

    2009-09-01

    Averaged kick maps are the sum of a series of individual kick maps, where each map is calculated from atomic coordinates modified by random shifts. These maps offer the possibility of an improved and less model-biased map interpretation. Use of reliable density maps is crucial for rapid and successful crystal structure determination. Here, the averaged kick (AK) map approach is investigated, its application is generalized and it is compared with other map-calculation methods. AK maps are the sum of a series of kick maps, where each kick map is calculated from atomic coordinates modified by random shifts. As such, theymore » are a numerical analogue of maximum-likelihood maps. AK maps can be unweighted or maximum-likelihood (σ{sub A}) weighted. Analysis shows that they are comparable and correspond better to the final model than σ{sub A} and simulated-annealing maps. The AK maps were challenged by a difficult structure-validation case, in which they were able to clarify the problematic region in the density without the need for model rebuilding. The conclusion is that AK maps can be useful throughout the entire progress of crystal structure determination, offering the possibility of improved map interpretation.« less

  8. Video attention deviation estimation using inter-frame visual saliency map analysis

    NASA Astrophysics Data System (ADS)

    Feng, Yunlong; Cheung, Gene; Le Callet, Patrick; Ji, Yusheng

    2012-01-01

    A viewer's visual attention during video playback is the matching of his eye gaze movement to the changing video content over time. If the gaze movement matches the video content (e.g., follow a rolling soccer ball), then the viewer keeps his visual attention. If the gaze location moves from one video object to another, then the viewer shifts his visual attention. A video that causes a viewer to shift his attention often is a "busy" video. Determination of which video content is busy is an important practical problem; a busy video is difficult for encoder to deploy region of interest (ROI)-based bit allocation, and hard for content provider to insert additional overlays like advertisements, making the video even busier. One way to determine the busyness of video content is to conduct eye gaze experiments with a sizable group of test subjects, but this is time-consuming and costineffective. In this paper, we propose an alternative method to determine the busyness of video-formally called video attention deviation (VAD): analyze the spatial visual saliency maps of the video frames across time. We first derive transition probabilities of a Markov model for eye gaze using saliency maps of a number of consecutive frames. We then compute steady state probability of the saccade state in the model-our estimate of VAD. We demonstrate that the computed steady state probability for saccade using saliency map analysis matches that computed using actual gaze traces for a range of videos with different degrees of busyness. Further, our analysis can also be used to segment video into shorter clips of different degrees of busyness by computing the Kullback-Leibler divergence using consecutive motion compensated saliency maps.

  9. English, Literacy and Neoliberal Policies: Mapping a Contested Moment in the United States

    ERIC Educational Resources Information Center

    Brass, Jory

    2014-01-01

    This essay maps some of the ways in which the professional knowledge of English teaching has been defined and positioned in the present moment in the United States. The first part of the essay traces multidisciplinary shifts in English education/literacy research that have expanded and shifted the discursive boundaries of teacher education and…

  10. The remote sensing image segmentation mean shift algorithm parallel processing based on MapReduce

    NASA Astrophysics Data System (ADS)

    Chen, Xi; Zhou, Liqing

    2015-12-01

    With the development of satellite remote sensing technology and the remote sensing image data, traditional remote sensing image segmentation technology cannot meet the massive remote sensing image processing and storage requirements. This article put cloud computing and parallel computing technology in remote sensing image segmentation process, and build a cheap and efficient computer cluster system that uses parallel processing to achieve MeanShift algorithm of remote sensing image segmentation based on the MapReduce model, not only to ensure the quality of remote sensing image segmentation, improved split speed, and better meet the real-time requirements. The remote sensing image segmentation MeanShift algorithm parallel processing algorithm based on MapReduce shows certain significance and a realization of value.

  11. Transfer Orbit Plasma Interaction Experiment (TROPIX)

    NASA Astrophysics Data System (ADS)

    Hickman, Mark

    Viewgraphs on the Transfer Orbit Plasma Interaction Experiment (TROPIX) are presented. Objectives of this research are (1) to map the charged particles in Earth's magnetosphere from LEO to GEO at high inclinations; (2) to measure plasma current collection and resulting shifts in vehicle electrical potential from LEO to GEO across range of orbital inclinations; (3) to study spacecraft interaction with plasma environment using solar electric propulsion (SEP) thrusters as plasma contactors; (4) to measure array degradation over mission duration; (5) to evaluate the potential of various microelectronics, spacecraft components, and instruments for future space missions; and (6) to demonstrate SEP technology applied to a flight vehicle. An overview of TROPIX is presented.

  12. Maps of interaural delay in the owl's nucleus laminaris

    PubMed Central

    Shah, Sahil; McColgan, Thomas; Ashida, Go; Kuokkanen, Paula T.; Brill, Sandra; Kempter, Richard; Wagner, Hermann

    2015-01-01

    Axons from the nucleus magnocellularis form a presynaptic map of interaural time differences (ITDs) in the nucleus laminaris (NL). These inputs generate a field potential that varies systematically with recording position and can be used to measure the map of ITDs. In the barn owl, the representation of best ITD shifts with mediolateral position in NL, so as to form continuous, smoothly overlapping maps of ITD with iso-ITD contours that are not parallel to the NL border. Frontal space (0°) is, however, represented throughout and thus overrepresented with respect to the periphery. Measurements of presynaptic conduction delay, combined with a model of delay line conduction velocity, reveal that conduction delays can account for the mediolateral shifts in the map of ITD. PMID:26224776

  13. A method to improve the B0 homogeneity of the heart in vivo.

    PubMed

    Jaffer, F A; Wen, H; Balaban, R S; Wolff, S D

    1996-09-01

    A homogeneous static (B0) magnetic field is required for many NMR experiments such as echo planar imaging, localized spectroscopy, and spiral scan imaging. Although semi-automated techniques have been described to improve the B0 field homogeneity, none has been applied to the in vivo heart. The acquisition of cardiac field maps is complicated by motion, blood flow, and chemical shift artifact from epicardial fat. To overcome these problems, an ungated three-dimensional (3D) chemical shift image (CSI) was collected to generate a time and motion-averaged B0 field map. B0 heterogeneity in the heart was minimized by using a previous algorithm that solves for the optimal shim coil currents for an input field map, using up to third-order current-bounded shims (1). The method improved the B0 homogenelty of the heart in all 11 normal volunteers studied. After application of the algorithm to the unshimmed cardiac field maps, the standard deviation of proton frequency decreased by 43%, the magnitude 1H spectral linewidth decreased by 24%, and the peak-peak gradient decreased by 35%. Simulations of the high-order (second- and third-order) shims in B0 field correction of the heart show that high order shims are important, resulting for nearly half of the improvement in homogeneity for several subjects. The T2* of the left ventricular anterior wall before and after field correction was determined at 4.0 Tesis. Finally, results show that cardiac shimming is of benefit in cardiac 31P NMR spectroscopy and cardiac echo planar imaging.

  14. Fast and slow transitions in frontal ensemble activity during flexible sensorimotor behavior.

    PubMed

    Siniscalchi, Michael J; Phoumthipphavong, Victoria; Ali, Farhan; Lozano, Marc; Kwan, Alex C

    2016-09-01

    The ability to shift between repetitive and goal-directed actions is a hallmark of cognitive control. Previous studies have reported that adaptive shifts in behavior are accompanied by changes of neural activity in frontal cortex. However, neural and behavioral adaptations can occur at multiple time scales, and their relationship remains poorly defined. Here we developed an adaptive sensorimotor decision-making task for head-fixed mice, requiring them to shift flexibly between multiple auditory-motor mappings. Two-photon calcium imaging of secondary motor cortex (M2) revealed different ensemble activity states for each mapping. When adapting to a conditional mapping, transitions in ensemble activity were abrupt and occurred before the recovery of behavioral performance. By contrast, gradual and delayed transitions accompanied shifts toward repetitive responding. These results demonstrate distinct ensemble signatures associated with the start versus end of sensory-guided behavior and suggest that M2 leads in engaging goal-directed response strategies that require sensorimotor associations.

  15. Optical image encryption using chaos-based compressed sensing and phase-shifting interference in fractional wavelet domain

    NASA Astrophysics Data System (ADS)

    Liu, Qi; Wang, Ying; Wang, Jun; Wang, Qiong-Hua

    2018-02-01

    In this paper, a novel optical image encryption system combining compressed sensing with phase-shifting interference in fractional wavelet domain is proposed. To improve the encryption efficiency, the volume data of original image are decreased by compressed sensing. Then the compacted image is encoded through double random phase encoding in asymmetric fractional wavelet domain. In the encryption system, three pseudo-random sequences, generated by three-dimensional chaos map, are used as the measurement matrix of compressed sensing and two random-phase masks in the asymmetric fractional wavelet transform. It not only simplifies the keys to storage and transmission, but also enhances our cryptosystem nonlinearity to resist some common attacks. Further, holograms make our cryptosystem be immune to noises and occlusion attacks, which are obtained by two-step-only quadrature phase-shifting interference. And the compression and encryption can be achieved in the final result simultaneously. Numerical experiments have verified the security and validity of the proposed algorithm.

  16. Pixel-by-pixel absolute phase retrieval using three phase-shifted fringe patterns without markers

    NASA Astrophysics Data System (ADS)

    Jiang, Chufan; Li, Beiwen; Zhang, Song

    2017-04-01

    This paper presents a method that can recover absolute phase pixel by pixel without embedding markers on three phase-shifted fringe patterns, acquiring additional images, or introducing additional hardware component(s). The proposed three-dimensional (3D) absolute shape measurement technique includes the following major steps: (1) segment the measured object into different regions using rough priori knowledge of surface geometry; (2) artificially create phase maps at different z planes using geometric constraints of structured light system; (3) unwrap the phase pixel by pixel for each region by properly referring to the artificially created phase map; and (4) merge unwrapped phases from all regions into a complete absolute phase map for 3D reconstruction. We demonstrate that conventional three-step phase-shifted fringe patterns can be used to create absolute phase map pixel by pixel even for large depth range objects. We have successfully implemented our proposed computational framework to achieve absolute 3D shape measurement at 40 Hz.

  17. Frequency Mapping of Rat Spinal Cord at 7T

    NASA Astrophysics Data System (ADS)

    Chen, Evan; Rauscher, Alexander; Kozlowski, Piotr; Yung, Andrew

    2012-10-01

    The spinal cord is an integral part of the nervous system responsible for sensory, motor, and reflex control crucial to all bodily function. Due to its non-invasive nature, MRI is well matched for characterizing and imaging of spinal cord, and is used extensively for clinical applications. Recent developments in magnetic resonance imaging (MRI) at high field (7T) using phase represents a new approach of characterizing spinal cord myelin. Theory suggests that microstructure differences in myelinated white matter (WM) and non-myelinated gray matter (GM) affect MR phase, measurable frequency shifts. Data from pilot experiments using a multi-gradient echo (MGE) sequence to image rat spinal cords placed parallel to main magnetic field B0 has shown frequency shifts between not only between WM and GM, but also between specific WM tracts of the dorsal column, including the fasciculus gracilis, fasciculus cuneatus, and corticospinal tract. Using MGE, frequency maps at multiple echo times (TE) between 4ms and 22ms show a non-linear relationship between WM frequency, contrary to what was previously expected. These results demonstrate the effectiveness of MGE in revealing new information about spinal cord tissue microstructure, and lays important groundwork for in-vivo and human studies.

  18. Multidimensional, mapping-based complex wavelet transforms.

    PubMed

    Fernandes, Felix C A; van Spaendonck, Rutger L C; Burrus, C Sidney

    2005-01-01

    Although the discrete wavelet transform (DWT) is a powerful tool for signal and image processing, it has three serious disadvantages: shift sensitivity, poor directionality, and lack of phase information. To overcome these disadvantages, we introduce multidimensional, mapping-based, complex wavelet transforms that consist of a mapping onto a complex function space followed by a DWT of the complex mapping. Unlike other popular transforms that also mitigate DWT shortcomings, the decoupled implementation of our transforms has two important advantages. First, the controllable redundancy of the mapping stage offers a balance between degree of shift sensitivity and transform redundancy. This allows us to create a directional, nonredundant, complex wavelet transform with potential benefits for image coding systems. To the best of our knowledge, no other complex wavelet transform is simultaneously directional and nonredundant. The second advantage of our approach is the flexibility to use any DWT in the transform implementation. As an example, we exploit this flexibility to create the complex double-density DWT: a shift-insensitive, directional, complex wavelet transform with a low redundancy of (3M - 1)/(2M - 1) in M dimensions. No other transform achieves all these properties at a lower redundancy, to the best of our knowledge. By exploiting the advantages of our multidimensional, mapping-based complex wavelet transforms in seismic signal-processing applications, we have demonstrated state-of-the-art results.

  19. High Resolution Image Reconstruction from Projection of Low Resolution Images DIffering in Subpixel Shifts

    NASA Technical Reports Server (NTRS)

    Mareboyana, Manohar; Le Moigne-Stewart, Jacqueline; Bennett, Jerome

    2016-01-01

    In this paper, we demonstrate a simple algorithm that projects low resolution (LR) images differing in subpixel shifts on a high resolution (HR) also called super resolution (SR) grid. The algorithm is very effective in accuracy as well as time efficiency. A number of spatial interpolation techniques using nearest neighbor, inverse-distance weighted averages, Radial Basis Functions (RBF) etc. used in projection yield comparable results. For best accuracy of reconstructing SR image by a factor of two requires four LR images differing in four independent subpixel shifts. The algorithm has two steps: i) registration of low resolution images and (ii) shifting the low resolution images to align with reference image and projecting them on high resolution grid based on the shifts of each low resolution image using different interpolation techniques. Experiments are conducted by simulating low resolution images by subpixel shifts and subsampling of original high resolution image and the reconstructing the high resolution images from the simulated low resolution images. The results of accuracy of reconstruction are compared by using mean squared error measure between original high resolution image and reconstructed image. The algorithm was tested on remote sensing images and found to outperform previously proposed techniques such as Iterative Back Projection algorithm (IBP), Maximum Likelihood (ML), and Maximum a posterior (MAP) algorithms. The algorithm is robust and is not overly sensitive to the registration inaccuracies.

  20. High Pressure Sensing and Dynamics Using High Speed Fiber Bragg Grating Interrogation Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rodriguez, G.; Sandberg, R. L.; Lalone, B. M.

    2014-06-01

    Fiber Bragg gratings (FBGs) are developing into useful sensing tools for measuring high pressure dynamics in extreme environments under shock loading conditions. Approaches using traditional diode array coupled FBG interrogation systems are often limited to readout speeds in the sub-MHz range. For shock wave physics, required detection speeds approaching 100 MHz are desired. We explore the use of two types of FBG sensing systems that are aimed at applying this technology as embedded high pressure probes for transient shock events. Both approaches measure time resolved spectral shifts in the return light from short (few mm long) uniform FBGs at 1550more » nm. In the first approach, we use a fiber coupled spectrometer to demultiplex spectral channels into an array (up to 12) of single element InGaAs photoreceivers. By monitoring the detectors during a shock impact event with high speed recording, we are able to track the pressure induced spectral shifting in FBG down to a time resolution of 20 ns. In the second approach, developed at the Special Technologies Lab, a coherent mode-locked fiber laser is used to illuminate the FBG sensor. After the sensor, wavelength-to-time mapping is accomplished with a chromatic dispersive element, and entire spectra are sampled using a single detector at the modelocked laser repetition rate of 50 MHz. By sampling with a 12 GHz InGaAs detector, direct wavelength mapping in time is recorded, and the pressure induced FBG spectral shift is sampled at 50 MHz. Here, the sensing systems are used to monitor the spectral shifts of FBGs that are immersed into liquid water and shock compressed using explosives. In this configuration, the gratings survive to pressures approaching 50 kbar. We describe both approaches and present the measured spectral shifts from the shock experiments.« less

  1. Highly noise-tolerant hybrid algorithm for phase retrieval from a single-shot spatial carrier fringe pattern

    NASA Astrophysics Data System (ADS)

    Dong, Zhichao; Cheng, Haobo

    2018-01-01

    A highly noise-tolerant hybrid algorithm (NTHA) is proposed in this study for phase retrieval from a single-shot spatial carrier fringe pattern (SCFP), which effectively combines the merits of spatial carrier phase shift method and two dimensional continuous wavelet transform (2D-CWT). NTHA firstly extracts three phase-shifted fringe patterns from the SCFP with one pixel malposition; then calculates phase gradients by subtracting the reference phase from the other two target phases, which are retrieved respectively from three phase-shifted fringe patterns by 2D-CWT; finally, reconstructs the phase map by a least square gradient integration method. Its typical characters include but not limited to: (1) doesn't require the spatial carrier to be constant; (2) the subtraction mitigates edge errors of 2D-CWT; (3) highly noise-tolerant, because not only 2D-CWT is noise-insensitive, but also the noise in the fringe pattern doesn't directly take part in the phase reconstruction as in previous hybrid algorithm. Its feasibility and performances are validated extensively by simulations and contrastive experiments to temporal phase shift method, Fourier transform and 2D-CWT methods.

  2. Off-axis electron holography of bacterial cells and magnetic nanoparticles in liquid

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prozorov, Tanya; Almeida, Trevor P.; Kovacs, Andras

    Here, the mapping of electrostatic potentials and magnetic fields in liquids using electron holography has been considered to be unrealistic. Here, we show that hydrated cells of Magnetospirillum magneticum strain AMB-1 and assemblies of magnetic nanoparticles can be studied using off-axis electron holography in a fluid cell specimen holder within the transmission electron microscope. Considering that the holographic object and reference wave both pass through liquid, the recorded electron holograms show sufficient interference fringe contrast to permit reconstruction of the phase shift of the electron wave and mapping of the magnetic induction from bacterial magnetite nanocrystals. We assess the challengesmore » of performing in situ magnetization reversal experiments using a fluid cell specimen holder, discuss approaches for improving spatial resolution and specimen stability, and outline future perspectives for studying scientific phenomena, ranging from interparticle interactions in liquids and electrical double layers at solid–liquid interfaces to biomineralization and the mapping of electrostatic potentials associated with protein aggregation and folding.« less

  3. Off-axis electron holography of bacterial cells and magnetic nanoparticles in liquid

    DOE PAGES

    Prozorov, Tanya; Almeida, Trevor P.; Kovacs, Andras; ...

    2017-10-02

    Here, the mapping of electrostatic potentials and magnetic fields in liquids using electron holography has been considered to be unrealistic. Here, we show that hydrated cells of Magnetospirillum magneticum strain AMB-1 and assemblies of magnetic nanoparticles can be studied using off-axis electron holography in a fluid cell specimen holder within the transmission electron microscope. Considering that the holographic object and reference wave both pass through liquid, the recorded electron holograms show sufficient interference fringe contrast to permit reconstruction of the phase shift of the electron wave and mapping of the magnetic induction from bacterial magnetite nanocrystals. We assess the challengesmore » of performing in situ magnetization reversal experiments using a fluid cell specimen holder, discuss approaches for improving spatial resolution and specimen stability, and outline future perspectives for studying scientific phenomena, ranging from interparticle interactions in liquids and electrical double layers at solid–liquid interfaces to biomineralization and the mapping of electrostatic potentials associated with protein aggregation and folding.« less

  4. Effects of shipping on marine acoustic habitats in Canadian Arctic estimated via probabilistic modeling and mapping.

    PubMed

    Aulanier, Florian; Simard, Yvan; Roy, Nathalie; Gervaise, Cédric; Bandet, Marion

    2017-12-15

    Canadian Arctic and Subarctic regions experience a rapid decrease of sea ice accompanied with increasing shipping traffic. The resulting time-space changes in shipping noise are studied for four key regions of this pristine environment, for 2013 traffic conditions and a hypothetical tenfold traffic increase. A probabilistic modeling and mapping framework, called Ramdam, which integrates the intrinsic variability and uncertainties of shipping noise and its effects on marine habitats, is developed and applied. A substantial transformation of soundscapes is observed in areas where shipping noise changes from present occasional-transient contributor to a dominant noise source. Examination of impacts on low-frequency mammals within ecologically and biologically significant areas reveals that shipping noise has the potential to trigger behavioral responses and masking in the future, although no risk of temporary or permanent hearing threshold shifts is noted. Such probabilistic modeling and mapping is strategic in marine spatial planning of this emerging noise issues. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  5. Cosmology with CLASS

    NASA Astrophysics Data System (ADS)

    Watts, Duncan; CLASS Collaboration

    2018-01-01

    The Cosmology Large Angular Scale Surveyor (CLASS) will use large-scale measurements of the polarized cosmic microwave background (CMB) to constrain the physics of inflation, reionization, and massive neutrinos. The experiment is designed to characterize the largest scales, which are inaccessible to most ground-based experiments, and remove Galactic foregrounds from the CMB maps. In this dissertation talk, I present simulations of CLASS data and demonstrate their ability to constrain the simplest single-field models of inflation and to reduce the uncertainty of the optical depth to reionization, τ, to near the cosmic variance limit, significantly improving on current constraints. These constraints will bring a qualitative shift in our understanding of standard ΛCDM cosmology. In particular, CLASS's measurement of τ breaks cosmological parameter degeneracies. Probes of large scale structure (LSS) test the effect of neutrino free-streaming at small scales, which depends on the mass of the neutrinos. CLASS's τ measurement, when combined with next-generation LSS and BAO measurements, will enable a 4σ detection of neutrino mass, compared with 2σ without CLASS data.. I will also briefly discuss the CLASS experiment's measurements of circular polarization of the CMB and the implications of the first-such near-all-sky map.

  6. Toward real-time temperature monitoring in fat and aqueous tissue during magnetic resonance-guided high-intensity focused ultrasound using a three-dimensional proton resonance frequency T1 method.

    PubMed

    Diakite, Mahamadou; Odéen, Henrik; Todd, Nick; Payne, Allison; Parker, Dennis L

    2014-07-01

    To present a three-dimensional (3D) segmented echoplanar imaging (EPI) pulse sequence implementation that provides simultaneously the proton resonance frequency shift temperature of aqueous tissue and the longitudinal relaxation time (T1 ) of fat during thermal ablation. The hybrid sequence was implemented by combining a 3D segmented flyback EPI sequence, the extended two-point Dixon fat and water separation, and the double flip angle T1 mapping techniques. High-intensity focused ultrasound (HIFU) heating experiments were performed at three different acoustic powers on excised human breast fat embedded in ex vivo porcine muscle. Furthermore, T1 calibrations with temperature in four different excised breast fat samples were performed, yielding an estimate of the average and variation of dT1 /dT across subjects. The water only images were used to mask the complex original data before computing the proton resonance frequency shift. T1 values were calculated from the fat-only images. The relative temperature coefficients were found in five fat tissue samples from different patients and ranged from 1.2% to 2.6%/°C. The results demonstrate the capability of real-time simultaneous temperature mapping in aqueous tissue and T1 mapping in fat during HIFU ablation, providing a potential tool for treatment monitoring in organs with large fat content, such as the breast. Copyright © 2013 Wiley Periodicals, Inc.

  7. A self-reference PRF-shift MR thermometry method utilizing the phase gradient

    NASA Astrophysics Data System (ADS)

    Langley, Jason; Potter, William; Phipps, Corey; Huang, Feng; Zhao, Qun

    2011-12-01

    In magnetic resonance (MR) imaging, the most widely used and accurate method for measuring temperature is based on the shift in proton resonance frequency (PRF). However, inter-scan motion and bulk magnetic field shifts can lead to inaccurate temperature measurements in the PRF-shift MR thermometry method. The self-reference PRF-shift MR thermometry method was introduced to overcome such problems by deriving a reference image from the heated or treated image, and approximates the reference phase map with low-order polynomial functions. In this note, a new approach is presented to calculate the baseline phase map in self-reference PRF-shift MR thermometry. The proposed method utilizes the phase gradient to remove the phase unwrapping step inherent to other self-reference PRF-shift MR thermometry methods. The performance of the proposed method was evaluated using numerical simulations with temperature distributions following a two-dimensional Gaussian function as well as phantom and in vivo experimental data sets. The results from both the numerical simulations and experimental data show that the proposed method is a promising technique for measuring temperature.

  8. Mapping the universe in three dimensions

    PubMed Central

    Haynes, Martha P.

    1996-01-01

    The determination of the three-dimensional layout of galaxies is critical to our understanding of the evolution of galaxies and the structures in which they lie, to our determination of the fundamental parameters of cosmology, and to our understanding of both the past and future histories of the universe at large. The mapping of the large scale structure in the universe via the determination of galaxy red shifts (Doppler shifts) is a rapidly growing industry thanks to technological developments in detectors and spectrometers at radio and optical wavelengths. First-order application of the red shift-distance relation (Hubble’s law) allows the analysis of the large-scale distribution of galaxies on scales of hundreds of megaparsecs. Locally, the large-scale structure is very complex but the overall topology is not yet clear. Comparison of the observed red shifts with ones expected on the basis of other distance estimates allows mapping of the gravitational field and the underlying total density distribution. The next decade holds great promise for our understanding of the character of large-scale structure and its origin. PMID:11607714

  9. Mapping the universe in three dimensions.

    PubMed

    Haynes, M P

    1996-12-10

    The determination of the three-dimensional layout of galaxies is critical to our understanding of the evolution of galaxies and the structures in which they lie, to our determination of the fundamental parameters of cosmology, and to our understanding of both the past and future histories of the universe at large. The mapping of the large scale structure in the universe via the determination of galaxy red shifts (Doppler shifts) is a rapidly growing industry thanks to technological developments in detectors and spectrometers at radio and optical wavelengths. First-order application of the red shift-distance relation (Hubble's law) allows the analysis of the large-scale distribution of galaxies on scales of hundreds of megaparsecs. Locally, the large-scale structure is very complex but the overall topology is not yet clear. Comparison of the observed red shifts with ones expected on the basis of other distance estimates allows mapping of the gravitational field and the underlying total density distribution. The next decade holds great promise for our understanding of the character of large-scale structure and its origin.

  10. Automation of peak-tracking analysis of stepwise perturbed NMR spectra.

    PubMed

    Banelli, Tommaso; Vuano, Marco; Fogolari, Federico; Fusiello, Andrea; Esposito, Gennaro; Corazza, Alessandra

    2017-02-01

    We describe a new algorithmic approach able to automatically pick and track the NMR resonances of a large number of 2D NMR spectra acquired during a stepwise variation of a physical parameter. The method has been named Trace in Track (TINT), referring to the idea that a gaussian decomposition traces peaks within the tracks recognised through 3D mathematical morphology. It is capable of determining the evolution of the chemical shifts, intensity and linewidths of each tracked peak.The performances obtained in term of track reconstruction and correct assignment on realistic synthetic spectra were high above 90% when a noise level similar to that of experimental data were considered. TINT was applied successfully to several protein systems during a temperature ramp in isotope exchange experiments. A comparison with a state-of-the-art algorithm showed promising results for great numbers of spectra and low signal to noise ratios, when the graduality of the perturbation is appropriate. TINT can be applied to different kinds of high throughput chemical shift mapping experiments, with quasi-continuous variations, in which a quantitative automated recognition is crucial.

  11. Image encryption algorithm based on multiple mixed hash functions and cyclic shift

    NASA Astrophysics Data System (ADS)

    Wang, Xingyuan; Zhu, Xiaoqiang; Wu, Xiangjun; Zhang, Yingqian

    2018-08-01

    This paper proposes a new one-time pad scheme for chaotic image encryption that is based on the multiple mixed hash functions and the cyclic-shift function. The initial value is generated using both information of the plaintext image and the chaotic sequences, which are calculated from the SHA1 and MD5 hash algorithms. The scrambling sequences are generated by the nonlinear equations and logistic map. This paper aims to improve the deficiencies of traditional Baptista algorithms and its improved algorithms. We employ the cyclic-shift function and piece-wise linear chaotic maps (PWLCM), which give each shift number the characteristics of chaos, to diffuse the image. Experimental results and security analysis show that the new scheme has better security and can resist common attacks.

  12. Mapping multisensory parietal face and body areas in humans.

    PubMed

    Huang, Ruey-Song; Chen, Ching-fu; Tran, Alyssa T; Holstein, Katie L; Sereno, Martin I

    2012-10-30

    Detection and avoidance of impending obstacles is crucial to preventing head and body injuries in daily life. To safely avoid obstacles, locations of objects approaching the body surface are usually detected via the visual system and then used by the motor system to guide defensive movements. Mediating between visual input and motor output, the posterior parietal cortex plays an important role in integrating multisensory information in peripersonal space. We used functional MRI to map parietal areas that see and feel multisensory stimuli near or on the face and body. Tactile experiments using full-body air-puff stimulation suits revealed somatotopic areas of the face and multiple body parts forming a higher-level homunculus in the superior posterior parietal cortex. Visual experiments using wide-field looming stimuli revealed retinotopic maps that overlap with the parietal face and body areas in the postcentral sulcus at the most anterior border of the dorsal visual pathway. Starting at the parietal face area and moving medially and posteriorly into the lower-body areas, the median of visual polar-angle representations in these somatotopic areas gradually shifts from near the horizontal meridian into the lower visual field. These results suggest the parietal face and body areas fuse multisensory information in peripersonal space to guard an individual from head to toe.

  13. Glue-Free Stacked Luminescent Nanosheets Enable High-Resolution Ratiometric Temperature Mapping in Living Small Animals.

    PubMed

    Miyagawa, Takuya; Fujie, Toshinori; Ferdinandus; Vo Doan, Tat Thang; Sato, Hirotaka; Takeoka, Shinji

    2016-12-14

    In this paper, a microthermograph, temperature mapping with high spatial resolution, was established using luminescent molecules embedded ultrathin polymeric films (nanosheets), and demonstrated in a living small animal to map out and visualize temperature shift due to animal's muscular activity. Herein, we report super flexible and self-adhesive (no need of glue) nanothermosensor consisting of stacked two different polymeric nanosheets with thermosensitive (Eu-tris (dinaphthoylmethane)-bis-trioctylphosphine oxide: EuDT) and insensitive (Rhodamine 800) dyes being embedded. Such stacked nanosheets allow for the ratiometric thermometry, with which the undesired luminescence intensity shift due to focal drift or animal's z-axis displacement is eliminated and the desired intensity shift solely due to the temperature shift of the sample (living muscle) can be acquired. With the stacked luminescent nanosheets, we achieved the first-ever demonstration of video filming of chronologically changing temperature-shift distribution from the rest state to the active state of the muscles in the living animal. The polymer nanosheet engineering and in vivo microthermography presented in the paper are promising technologies to microscopically explore the heat production and heat transfer in living cells, tissues, and organisms with high spatial resolution beyond what existing thermometric technologies such as infrared thermography have ever achieved.

  14. Typicality Shift in Semantic Categories as a Result of Cultural Transition: Evidence from Jewish Argentine Immigrants in Israel.

    ERIC Educational Resources Information Center

    Shimron, Joseph; Chernitsky, Roberto

    1995-01-01

    Investigates changes in the internal structure of semantic categories as a result of cultural transition. Examines typicality shifts in semantic categories of Jewish Argentine immigrants in Israel. Presents a model mapping typicality shift patterns onto acculturation patterns. (HB)

  15. Geologic Map of the Snegurochka Planitia Quadrangle (V-1): Implications for Tectonic and Volcanic History of the North Polar Region of Venus

    NASA Technical Reports Server (NTRS)

    Hurwitz, D. M.; Head, J. W.

    2009-01-01

    Geologic mapping of Snegurochka Planitia (V-1) reveals a complex stratigraphy of tectonic and volcanic features that can provide insight into the geologic history of Venus and Archean Earth [1,2], including 1) episodes of both localized crustal uplift and mantle downwelling, 2) shifts from local to regional volcanic activity, and 3) a shift back to local volcanic activity. We present our progress in mapping the spatial and stratigraphic relationships of material units and our initial interpretations of the tectonic and volcanic history of the region surrounding the north pole of Venus

  16. High-speed three-dimensional shape measurement for dynamic scenes using bi-frequency tripolar pulse-width-modulation fringe projection

    NASA Astrophysics Data System (ADS)

    Zuo, Chao; Chen, Qian; Gu, Guohua; Feng, Shijie; Feng, Fangxiaoyu; Li, Rubin; Shen, Guochen

    2013-08-01

    This paper introduces a high-speed three-dimensional (3-D) shape measurement technique for dynamic scenes by using bi-frequency tripolar pulse-width-modulation (TPWM) fringe projection. Two wrapped phase maps with different wavelengths can be obtained simultaneously by our bi-frequency phase-shifting algorithm. Then the two phase maps are unwrapped using a simple look-up-table based number-theoretical approach. To guarantee the robustness of phase unwrapping as well as the high sinusoidality of projected patterns, TPWM technique is employed to generate ideal fringe patterns with slight defocus. We detailed our technique, including its principle, pattern design, and system setup. Several experiments on dynamic scenes were performed, verifying that our method can achieve a speed of 1250 frames per second for fast, dense, and accurate 3-D measurements.

  17. Multisensor monitoring of deforestation in the Guinea Highlands of West Africa

    NASA Technical Reports Server (NTRS)

    Gilruth, Peter T.; Hutchinson, Charles F.

    1990-01-01

    Multiple remote sensing systems were used to assess deforestation in the Guinea Highlands (Fouta Djallon) of West Africa. Sensor systems included: (1) historical (1953) and current (1989) aerial mapping photography; (2) current large-scale, small format (35mm) aerial photography; (3) current aerial video imagery; and (4) historical (1973) and recent (1985) LANDSAT MSS. Photographic and video data were manually interpreted and incorporated in a vector-based geographic information system (GIS). LANDSAT data were digitally classified. General results showed an increase in permanent and shifting agriculture over the past 35 years. This finding is consistent with hypothesized strategies to increase agricultural production through a shortening of the fallow period in areas of shifting cultivation. However, results also show that the total area of both permanent and shifting agriculture had expanded at the expense of natural vegetation and an increase in erosion. Although sequential LANDSAT MSS cannot be used in this region to accurately map land over, the location, direction and magnitude of changes can be detected in relative terms. Historical and current aerial photography can be used to map agricultural land use changes with some accuracy. Video imagery is useful as ancillary data for mapping vegetation. The most prudent approach to mapping deforestation would incorporate a multistage approach based on these sensors.

  18. Secure communication based on spatiotemporal chaos

    NASA Astrophysics Data System (ADS)

    Ren, Hai-Peng; Bai, Chao

    2015-08-01

    In this paper, we propose a novel approach to secure communication based on spatiotemporal chaos. At the transmitter end, the state variables of the coupled map lattice system are divided into two groups: one is used as the key to encrypt the plaintext in the N-shift encryption function, and the other is used to mix with the output of the N-shift function to further confuse the information to transmit. At the receiver end, the receiver lattices are driven by the received signal to synchronize with the transmitter lattices and an inverse procedure of the encoding is conducted to decode the information. Numerical simulation and experiment based on the TI TMS320C6713 Digital Signal Processor (DSP) show the feasibility and the validity of the proposed scheme. Project supported by the National Natural Science Foundation of China (Grant No. 61172070) and the Funds from the Science and Technology Innovation Team of Shaanxi Province, China (Grant No. 2013CKT-04).

  19. Random waves in the brain: Symmetries and defect generation in the visual cortex

    NASA Astrophysics Data System (ADS)

    Schnabel, M.; Kaschube, M.; Löwel, S.; Wolf, F.

    2007-06-01

    How orientation maps in the visual cortex of the brain develop is a matter of long standing debate. Experimental and theoretical evidence suggests that their development represents an activity-dependent self-organization process. Theoretical analysis [1] exploring this hypothesis predicted that maps at an early developmental stage are realizations of Gaussian random fields exhibiting a rigorous lower bound for their densities of topological defects, called pinwheels. As a consequence, lower pinwheel densities, if observed in adult animals, are predicted to develop through the motion and annihilation of pinwheel pairs. Despite of being valid for a large class of developmental models this result depends on the symmetries of the models and thus of the predicted random field ensembles. In [1] invariance of the orientation map's statistical properties under independent space rotations and orientation shifts was assumed. However, full rotation symmetry appears to be broken by interactions of cortical neurons, e.g. selective couplings between groups of neurons with collinear orientation preferences [2]. A recently proposed new symmetry, called shift-twist symmetry [3], stating that spatial rotations have to occur together with orientation shifts in order to be an appropriate symmetry transformation, is more consistent with this organization. Here we generalize our random field approach to this important symmetry class. We propose a new class of shift-twist symmetric Gaussian random fields and derive the general correlation functions of this ensemble. It turns out that despite strong effects of the shift-twist symmetry on the structure of the correlation functions and on the map layout the lower bound on the pinwheel densities remains unaffected, predicting pinwheel annihilation in systems with low pinwheel densities.

  20. Near-infrared voltage-sensitive fluorescent dyes optimized for optical mapping in blood-perfused myocardium.

    PubMed

    Matiukas, Arvydas; Mitrea, Bogdan G; Qin, Maochun; Pertsov, Arkady M; Shvedko, Alexander G; Warren, Mark D; Zaitsev, Alexey V; Wuskell, Joseph P; Wei, Mei-de; Watras, James; Loew, Leslie M

    2007-11-01

    Styryl voltage-sensitive dyes (e.g., di-4-ANEPPS) have been used successfully for optical mapping in cardiac cells and tissues. However, their utility for probing electrical activity deep inside the myocardial wall and in blood-perfused myocardium has been limited because of light scattering and high absorption by endogenous chromophores and hemoglobin at blue-green excitation wavelengths. The purpose of this study was to characterize two new styryl dyes--di-4-ANBDQPQ (JPW-6003) and di-4-ANBDQBS (JPW-6033)--optimized for blood-perfused tissue and intramural optical mapping. Voltage-dependent spectra were recorded in a model lipid bilayer. Optical mapping experiments were conducted in four species (mouse, rat, guinea pig, and pig). Hearts were Langendorff perfused using Tyrode's solution and blood (pig). Dyes were loaded via bolus injection into perfusate. Transillumination experiments were conducted in isolated coronary-perfused pig right ventricular wall preparations. The optimal excitation wavelength in cardiac tissues (650 nm) was >70 nm beyond the absorption maximum of hemoglobin. Voltage sensitivity of both dyes was approximately 10% to 20%. Signal decay half-life due to dye internalization was 80 to 210 minutes, which is 5 to 7 times slower than for di-4-ANEPPS. In transillumination mode, DeltaF/F was as high as 20%. In blood-perfused tissues, DeltaF/F reached 5.5% (1.8 times higher than for di-4-ANEPPS). We have synthesized and characterized two new near-infrared dyes with excitation/emission wavelengths shifted >100 nm to the red. They provide both high voltage sensitivity and 5 to 7 times slower internalization rate compared to conventional dyes. The dyes are optimized for deeper tissue probing and optical mapping of blood-perfused tissue, but they also can be used for conventional applications.

  1. Shifts in climate suitability for wine production as a result of climate change in a temperate climate wine region of Romania

    NASA Astrophysics Data System (ADS)

    Irimia, Liviu Mihai; Patriche, Cristian Valeriu; Quenol, Hervé; Sfîcă, Lucian; Foss, Chris

    2018-02-01

    Climate change is causing important shifts in the suitability of regions for wine production. Fine scale mapping of these shifts helps us to understand the evolution of vineyard climates, and to find solutions through viticultural adaptation. The aim of this study is to identify and map the structural and spatial shifts that occurred in the climatic suitability for wine production of the Cotnari wine growing region (Romania) between 1961 and 2013. Discontinuities in trends of temperature were identified, and the averages and trends of 13 climatic parameters for the 1961 to 1980 and 1981 to 2013 time periods were analysed. Using the averages of these climatic parameters, climate suitability for wine production was calculated at a resolution of 30 m and mapped for each time period, and the changes analysed. The results indicate shifts in the area's historic climatic profile, due to an increase of heliothermal resources and precipitation constancy. The area's climate suitability for wine production was modified by the loss of climate suitability for white table wines, sparkling wines and wine for distillates; shifts in suitability to higher altitudes by about 67 m, and a 48.6% decrease in the area suitable for quality white wines; and the occurrence of suitable climates for red wines at lower altitudes. The study showed that climate suitability for wine production has a multi-level spatial structure, with classes requiring a cooler climate being located at a higher altitude than those requiring a warmer climate. Climate change has therefore resulted in the shift of climate suitability classes for wine production to higher altitudes.

  2. Between Clinic and Experiment: Wilder Penfield's Stimulation Reports and the Search for Mind, 1929-55.

    PubMed

    Guenther, Katja

    In medicine, the realm of the clinic and the realm of experimentation often overlap and conflict, and physicians have to develop practices to negotiate their differences. The work of Canadian neurosurgeon Wilder Penfield (1891-1976) is a case in point. Engaging closely with the nearly 5,000 pages of unpublished and hitherto unconsidered reports of electrical cortical stimulation that Penfield compiled between 1929 and 1955, I trace how Penfield's interest shifted from the production of hospital-based records designed to help him navigate the brains of individual patients to the construction of universal brain maps to aid his search for an ever-elusive "mind." Reading the developments of Penfield's operation records over time, I examine the particular ways in which Penfield straddled the individual and the universal while attempting to align his clinical and scientific interests, thereby exposing his techniques to standardize and normalize his brain maps.

  3. Changing Predictors of Map Use in Wayfinding.

    ERIC Educational Resources Information Center

    Scholnick, Ellin Kofsky; And Others

    Using a map for guiding travel requires: (1) skills in encoding information from a terrain and a map; (2) finding a match between the two; and (3) maintaining the match despite directional shifts from turns on a route. In order to test this analysis, 94 children between the ages of 4 and 6 used maps to locate the route to a goal through a network…

  4. Evolution of Muscle Activity Patterns Driving Motions of the Jaw and Hyoid during Chewing in Gnathostomes

    PubMed Central

    Konow, Nicolai; Herrel, Anthony; Ross, Callum F.; Williams, Susan H.; German, Rebecca Z.; Sanford, Christopher P. J.; Gintof, Chris

    2011-01-01

    Although chewing has been suggested to be a basal gnathostome trait retained in most major vertebrate lineages, it has not been studied broadly and comparatively across vertebrates. To redress this imbalance, we recorded EMG from muscles powering anteroposterior movement of the hyoid, and dorsoventral movement of the mandibular jaw during chewing. We compared muscle activity patterns (MAP) during chewing in jawed vertebrate taxa belonging to unrelated groups of basal bony fishes and artiodactyl mammals. Our aim was to outline the evolution of coordination in MAP. Comparisons of activity in muscles of the jaw and hyoid that power chewing in closely related artiodactyls using cross-correlation analyses identified reorganizations of jaw and hyoid MAP between herbivores and omnivores. EMG data from basal bony fishes revealed a tighter coordination of jaw and hyoid MAP during chewing than seen in artiodactyls. Across this broad phylogenetic range, there have been major structural reorganizations, including a reduction of the bony hyoid suspension, which is robust in fishes, to the acquisition in a mammalian ancestor of a muscle sling suspending the hyoid. These changes appear to be reflected in a shift in chewing MAP that occurred in an unidentified anamniote stem-lineage. This shift matches observations that, when compared with fishes, the pattern of hyoid motion in tetrapods is reversed and also time-shifted relative to the pattern of jaw movement. PMID:21705368

  5. Leading to a New Paradigm: The Example of Bioregional Mapping.

    ERIC Educational Resources Information Center

    Shapiro, David W.

    1996-01-01

    Examines bioregional mapping as an example of how a different system (educational or otherwise) could be designed through shifting the focus of figure-ground gestalts and revisioning core metaphors. Discusses the notions of community and place, the potential for cognitive restructuring, literal and conceptual maps, and the potential of solving…

  6. Baryon Acoustic Oscillations reconstruction with pixels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Obuljen, Andrej; Villaescusa-Navarro, Francisco; Castorina, Emanuele

    2017-09-01

    Gravitational non-linear evolution induces a shift in the position of the baryon acoustic oscillations (BAO) peak together with a damping and broadening of its shape that bias and degrades the accuracy with which the position of the peak can be determined. BAO reconstruction is a technique developed to undo part of the effect of non-linearities. We present and analyse a reconstruction method that consists of displacing pixels instead of galaxies and whose implementation is easier than the standard reconstruction method. We show that this method is equivalent to the standard reconstruction technique in the limit where the number of pixelsmore » becomes very large. This method is particularly useful in surveys where individual galaxies are not resolved, as in 21cm intensity mapping observations. We validate this method by reconstructing mock pixelated maps, that we build from the distribution of matter and halos in real- and redshift-space, from a large set of numerical simulations. We find that this method is able to decrease the uncertainty in the BAO peak position by 30-50% over the typical angular resolution scales of 21 cm intensity mapping experiments.« less

  7. Rapid tuning shifts in human auditory cortex enhance speech intelligibility

    PubMed Central

    Holdgraf, Christopher R.; de Heer, Wendy; Pasley, Brian; Rieger, Jochem; Crone, Nathan; Lin, Jack J.; Knight, Robert T.; Theunissen, Frédéric E.

    2016-01-01

    Experience shapes our perception of the world on a moment-to-moment basis. This robust perceptual effect of experience parallels a change in the neural representation of stimulus features, though the nature of this representation and its plasticity are not well-understood. Spectrotemporal receptive field (STRF) mapping describes the neural response to acoustic features, and has been used to study contextual effects on auditory receptive fields in animal models. We performed a STRF plasticity analysis on electrophysiological data from recordings obtained directly from the human auditory cortex. Here, we report rapid, automatic plasticity of the spectrotemporal response of recorded neural ensembles, driven by previous experience with acoustic and linguistic information, and with a neurophysiological effect in the sub-second range. This plasticity reflects increased sensitivity to spectrotemporal features, enhancing the extraction of more speech-like features from a degraded stimulus and providing the physiological basis for the observed ‘perceptual enhancement' in understanding speech. PMID:27996965

  8. Positive Contrast Visualization of Nitinol Devices using Susceptibility Gradient Mapping

    PubMed Central

    Vonken, Evert-jan P.A.; Schär, Michael; Stuber, Matthias

    2008-01-01

    MRI visualization of devices is traditionally based on the signal loss due to T2* effects originating from the local susceptibility differences. To visualize nitinol devices with positive contrast a recently introduced post processing method is adapted to map the induced susceptibility gradients. This method operates on regular gradient echo MR images and maps the shift in k-space in a (small) neighborhood of every voxel by Fourier analysis followed by a center of mass calculation. The quantitative map of the local shifts generates the positive contrast image of the devices, while areas without susceptibility gradients render a background with noise only. The positive signal response of this method depends only on the choice of the voxel neighborhood size. The properties of the method are explained and the visualization of a nitinol wire and two stents are shown for illustration. PMID:18727096

  9. STS-99 Flight Day Highlights and Crew Activities Report

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Live footage shows the Blue Team (second of the dual shift crew), Dominic L. Pudwill Gorie, Janice E. Voss and Mamoru Mohri, beginning the first mapping swath covering a 140-mile-wide path. While Mohri conducts mapping operations, Voss and Gorie are seen participating in a news conference with correspondents from NBC and CNN. The Red Team (first of the dual shift crew), Kevin R. Kregel, Janet L. Kavandi and Gerhard P.J. Thiele, relieves the Blue Team and are seen continuing the mapping operations for this around the clock Shuttle Radar Topography Mission (SRTM). Commander Kregel is shown performing boom (mass) durability tests, calibrating the EarthCam Payload, and speaking with the Launch Control Center (LCC) about trouble shooting a bracket for better camera angle.

  10. Sustaining Nurse-Led Task-Shifting Strategies for Hypertension Control: A Concept Mapping Study to Inform Evidence-Based Practice.

    PubMed

    Blackstone, Sarah; Iwelunmor, Juliet; Plange-Rhule, Jacob; Gyamfi, Joyce; Quakyi, Nana Kofi; Ntim, Micheal; Ogedegbe, Gbenga

    2017-10-01

    The use of task-shifting is an increasingly widespread delivery approach for health interventions targeting prevention, treatment, and control of hypertension in adults living in sub-Saharan Africa (SSA). Addressing a gap in the literature, this research examined the sustainability of an ongoing task-shifting strategy for hypertension (TASSH) from the perspectives of community health nurses (CHNs) implementing the program. We used concept-mapping, a mixed-methods participatory approach to understand CHNs' perceptions of barriers and enablers to sustaining a task-shifting program. Participants responded to focal prompts, eliciting statements regarding perceived barriers and enablers to sustaining TASSH, and then rated these ideas based on importance to the research questions and feasibility to address. Twenty-eight community health nurses (21 women, 7 men) from the Ashanti region of Ghana completed the concept-mapping process. Factors influencing sustainability were grouped into five categories: Limited Drug Supply, Financial Support, Provision of Primary Health Care, Personnel Training, and Patient-Provider Communication. The limited supply of antihypertensive medication was considered by CHNs as the most important item to address, while providing training for intervention personnel was considered most feasible to address. This study's findings highlight the importance of examining nurses' perceptions of factors likely to influence the sustainability of evidence-based, task-shifting interventions. Nurses' perceptions can guide the widespread uptake and dissemination of these interventions in resource-limited settings. © 2017 Sigma Theta Tau International.

  11. Quantitation Error in 1H MRS Caused by B1 Inhomogeneity and Chemical Shift Displacement.

    PubMed

    Watanabe, Hidehiro; Takaya, Nobuhiro

    2017-11-08

    The quantitation accuracy in proton magnetic resonance spectroscopy ( 1 H MRS) improves at higher B 0 field. However, a larger chemical shift displacement (CSD) and stronger B 1 inhomogeneity exist. In this work, we evaluate the quantitation accuracy for the spectra of metabolite mixtures in phantom experiments at 4.7T. We demonstrate a position-dependent error in quantitation and propose a correction method by measuring water signals. All experiments were conducted on a whole-body 4.7T magnetic resonance (MR) system with a quadrature volume coil for transmission and reception. We arranged three bottles filled with metabolite solutions of N-acetyl aspartate (NAA) and creatine (Cr) in a vertical row inside a cylindrical phantom filled with water. Peak areas of three singlets of NAA and Cr were measured on three 1 H spectra at three volume of interests (VOIs) inside three bottles. We also measured a series of water spectra with a shifted carrier frequency and measured a reception sensitivity map. The ratios of NAA and Cr at 3.92 ppm to Cr at 3.01 ppm differed amongst the three VOIs in peak area, which leads to a position-dependent error. The nature of slope depicting the relationship between peak areas and the shifted values of frequency was like that between the reception sensitivities and displacement at every VOI. CSD and inhomogeneity of reception sensitivity cause amplitude modulation along the direction of chemical shift on the spectra, resulting in a quantitation error. This error may be more significant at higher B 0 field where CSD and B 1 inhomogeneity are more severe. This error may also occur in reception using a surface coil having inhomogeneous B 1 . Since this type of error is around a few percent, the data should be analyzed with greater attention while discussing small differences in the studies of 1 H MRS.

  12. In vivo three-dimensional molecular imaging with Biosensor Imaging of Redundant Deviation in Shifts (BIRDS) at high spatiotemporal resolution.

    PubMed

    Coman, Daniel; de Graaf, Robin A; Rothman, Douglas L; Hyder, Fahmeed

    2013-11-01

    Spectroscopic signals which emanate from complexes between paramagnetic lanthanide (III) ions (e.g. Tm(3+)) and macrocyclic chelates (e.g. 1,4,7,10-tetramethyl-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate, or DOTMA(4-)) are sensitive to physiology (e.g. temperature). Because nonexchanging protons from these lanthanide-based macrocyclic agents have relaxation times on the order of a few milliseconds, rapid data acquisition is possible with chemical shift imaging (CSI). Thus, Biosensor Imaging of Redundant Deviation in Shifts (BIRDS) which originate from nonexchanging protons of these paramagnetic agents, but exclude water proton detection, can allow molecular imaging. Previous two-dimensional CSI experiments with such lanthanide-based macrocyclics allowed acquisition from ~12-μL voxels in rat brain within 5 min using rectangular encoding of k space. Because cubical encoding of k space in three dimensions for whole-brain coverage increases the CSI acquisition time to several tens of minutes or more, a faster CSI technique is required for BIRDS to be of practical use. Here, we demonstrate a CSI acquisition method to improve three-dimensional molecular imaging capabilities with lanthanide-based macrocyclics. Using TmDOTMA(-), we show datasets from a 20 × 20 × 20-mm(3) field of view with voxels of ~1 μL effective volume acquired within 5 min (at 11.7 T) for temperature mapping. By employing reduced spherical encoding with Gaussian weighting (RESEGAW) instead of cubical encoding of k space, a significant increase in CSI signal is obtained. In vitro and in vivo three-dimensional CSI data with TmDOTMA(-), and presumably similar lanthanide-based macrocyclics, suggest that acquisition using RESEGAW can be used for high spatiotemporal resolution molecular mapping with BIRDS. Copyright © 2013 John Wiley & Sons, Ltd.

  13. 3D mapping of breast surface using digital fringe projection

    NASA Astrophysics Data System (ADS)

    Vairavan, Rajendaran; Retnasamy, Vithyacharan; Mohamad Shahimin, Mukhzeer; Sauli, Zaliman; Leng, Lai Siang; Wan Norhaimi, Wan Mokhzani; Marimuthu, Rajeswaran; Abdullah, Othman; Kirtsaeng, Supap

    2017-02-01

    Optical sensing technique has inherited non-contact nature for generating 3D surface mapping where its application ranges from MEMS component characterization, corrosion analysis, and vibration analysis. In particular, the digital fringe projection is utilized for 3D mapping of objects through the illumination of structured light for medical application extending from oral dental measurements, lower back deformation analysis, monitoring of scoliosis and 3D face reconstruction for biometric identification. However, the usage of digital fringe projection for 3D mapping of human breast is very minimal. Thus, this paper addresses the application of digital fringe projection for 3D mapping of breast surface based on total non-contact nature. In this work, phase shift method is utilized to perform the 3D mapping. The phase shifted fringe pattern are displayed through a digital projector onto the breast surface, and the distorted fringe patterns are captured by a CCD camera. A phase map is produced, and phase unwrapping was executed to obtain the 3D surface mapping of the breast. The surface height profile from 3D fringe projection was compared with the surface height measured by a direct method using electronic digital vernier caliper. Preliminary results showed the feasibility of digital fringe projection in providing a 3D mapping of breast and its application could be further extended for breast carcinoma detection.

  14. Determination of Shift/Bias in Digital Aerial Triangulation of UAV Imagery Sequences

    NASA Astrophysics Data System (ADS)

    Wierzbicki, Damian

    2017-12-01

    Currently UAV Photogrammetry is characterized a largely automated and efficient data processing. Depicting from the low altitude more often gains on the meaning in the uses of applications as: cities mapping, corridor mapping, road and pipeline inspections or mapping of large areas e.g. forests. Additionally, high-resolution video image (HD and bigger) is more often use for depicting from the low altitude from one side it lets deliver a lot of details and characteristics of ground surfaces features, and from the other side is presenting new challenges in the data processing. Therefore, determination of elements of external orientation plays a substantial role the detail of Digital Terrain Models and artefact-free ortophoto generation. Parallel a research on the quality of acquired images from UAV and above the quality of products e.g. orthophotos are conducted. Despite so fast development UAV photogrammetry still exists the necessity of accomplishment Automatic Aerial Triangulation (AAT) on the basis of the observations GPS/INS and via ground control points. During low altitude photogrammetric flight, the approximate elements of external orientation registered by UAV are burdened with the influence of some shift/bias errors. In this article, methods of determination shift/bias error are presented. In the process of the digital aerial triangulation two solutions are applied. In the first method shift/bias error was determined together with the drift/bias error, elements of external orientation and coordinates of ground control points. In the second method shift/bias error was determined together with the elements of external orientation, coordinates of ground control points and drift/bias error equals 0. When two methods were compared the difference for shift/bias error is more than ±0.01 m for all terrain coordinates XYZ.

  15. SWOT analysis on National Common Geospatial Information Service Platform of China

    NASA Astrophysics Data System (ADS)

    Zheng, Xinyan; He, Biao

    2010-11-01

    Currently, the trend of International Surveying and Mapping is shifting from map production to integrated service of geospatial information, such as GOS of U.S. etc. Under this circumstance, the Surveying and Mapping of China is inevitably shifting from 4D product service to NCGISPC (National Common Geospatial Information Service Platform of China)-centered service. Although State Bureau of Surveying and Mapping of China has already provided a great quantity of geospatial information service to various lines of business, such as emergency and disaster management, transportation, water resource, agriculture etc. The shortcomings of the traditional service mode are more and more obvious, due to the highly emerging requirement of e-government construction, the remarkable development of IT technology and emerging online geospatial service demands of various lines of business. NCGISPC, which aimed to provide multiple authoritative online one-stop geospatial information service and API for further development to government, business and public, is now the strategic core of SBSM (State Bureau of Surveying and Mapping of China). This paper focuses on the paradigm shift that NCGISPC brings up by using SWOT (Strength, Weakness, Opportunity and Threat) analysis, compared to the service mode that based on 4D product. Though NCGISPC is still at its early stage, it represents the future service mode of geospatial information of China, and surely will have great impact not only on the construction of digital China, but also on the way that everyone uses geospatial information service.

  16. Single-shot real-time three dimensional measurement based on hue-height mapping

    NASA Astrophysics Data System (ADS)

    Wan, Yingying; Cao, Yiping; Chen, Cheng; Fu, Guangkai; Wang, Yapin; Li, Chengmeng

    2018-06-01

    A single-shot three-dimensional (3D) measurement based on hue-height mapping is proposed. The color fringe pattern is encoded by three sinusoidal fringes with the same frequency but different shifting phase into red (R), green (G) and blue (B) color channels, respectively. It is found that the hue of the captured color fringe pattern on the reference plane maintains monotonic in one period even it has the color crosstalk. Thus, unlike the traditional color phase shifting technique, the hue information is utilized to decode the color fringe pattern and map to the pixels of the fringe displacement in the proposed method. Because the monotonicity of the hue is limited within one period, displacement unwrapping is proposed to obtain the continuous displacement that is finally used to map to the height distribution. This method directly utilizes the hue under the effect of color crosstalk for mapping the height so that no color calibration is involved. Also, as it requires only single shot deformed color fringe pattern, this method can be applied into the real-time or dynamic 3D measurements.

  17. Geologic Map of the Snegurochka Planitia Quadrangle (V-1): Implications for the Volcanic History of the North Polar Region of Venus

    NASA Technical Reports Server (NTRS)

    Hurwitz, D. M.; Head, J. W.

    2010-01-01

    Geologic mapping of Snegurochka Planitia (V-1) reveals a complex stratigraphy of tectonic and volcanic features that can provide insight into the geologic history of Venus and Archean Earth [1,2], including 1) episodes of both localized crustal uplift and mantle downwelling, 2) shifts from local to regional volcanic activity, and 3) a shift back to local volcanic activity. We present our interpretations of the volcanic history of the region surrounding the north pole of Venus and explore how analysis of new data support our interpretations

  18. Scaling Relations for Adsorption Energies on Doped Molybdenum Phosphide Surfaces

    DOE PAGES

    Fields, Meredith; Tsai, Charlie; Chen, Leanne D.; ...

    2017-03-10

    Molybdenum phosphide (MoP), a well-documented catalyst for applications ranging from hydrotreating reactions to electrochemical hydrogen evolution, has yet to be mapped from a more fundamental perspective, particularly in the context of transition-metal scaling relations. In this work, we use periodic density functional theory to extend linear scaling arguments to doped MoP surfaces and understand the behavior of the phosphorus active site. The derived linear relationships for hydrogenated C, N, and O species on a variety of doped surfaces suggest that phosphorus experiences a shift in preferred bond order depending on the degree of hydrogen substitution on the adsorbate molecule. Thismore » shift in phosphorus hybridization, dependent on the bond order of the adsorbate to the surface, can result in selective bond weakening or strengthening of chemically similar species. As a result, we discuss how this behavior deviates from transition-metal, sulfide, carbide, and nitride scaling relations, and we discuss potential applications in the context of electrochemical reduction reactions.« less

  19. Krylov Subspace Methods for Complex Non-Hermitian Linear Systems. Thesis

    NASA Technical Reports Server (NTRS)

    Freund, Roland W.

    1991-01-01

    We consider Krylov subspace methods for the solution of large sparse linear systems Ax = b with complex non-Hermitian coefficient matrices. Such linear systems arise in important applications, such as inverse scattering, numerical solution of time-dependent Schrodinger equations, underwater acoustics, eddy current computations, numerical computations in quantum chromodynamics, and numerical conformal mapping. Typically, the resulting coefficient matrices A exhibit special structures, such as complex symmetry, or they are shifted Hermitian matrices. In this paper, we first describe a Krylov subspace approach with iterates defined by a quasi-minimal residual property, the QMR method, for solving general complex non-Hermitian linear systems. Then, we study special Krylov subspace methods designed for the two families of complex symmetric respectively shifted Hermitian linear systems. We also include some results concerning the obvious approach to general complex linear systems by solving equivalent real linear systems for the real and imaginary parts of x. Finally, numerical experiments for linear systems arising from the complex Helmholtz equation are reported.

  20. Effect of brain shift on the creation of functional atlases for deep brain stimulation surgery

    PubMed Central

    Pallavaram, Srivatsan; Remple, Michael S.; Neimat, Joseph S.; Kao, Chris; Konrad, Peter E.; D’Haese, Pierre-François

    2011-01-01

    Purpose In the recent past many groups have tried to build functional atlases of the deep brain using intra-operatively acquired information such as stimulation responses or micro-electrode recordings. An underlying assumption in building such atlases is that anatomical structures do not move between pre-operative imaging and intra-operative recording. In this study, we present evidences that this assumption is not valid. We quantify the effect of brain shift between pre-operative imaging and intra-operative recording on the creation of functional atlases using intra-operative somatotopy recordings and stimulation response data. Methods A total of 73 somatotopy points from 24 bilateral subthalamic nucleus (STN) implantations and 52 eye deviation stimulation response points from 17 bilateral STN implantations were used. These points were spatially normalized on a magnetic resonance imaging (MRI) atlas using a fully automatic non-rigid registration algorithm. Each implantation was categorized as having low, medium or large brain shift based on the amount of pneumocephalus visible on post-operative CT. The locations of somatotopy clusters and stimulation maps were analyzed for each category. Results The centroid of the large brain shift cluster of the somatotopy data (posterior, lateral, inferior: 3.06, 11.27, 5.36 mm) was found posterior, medial and inferior to that of the medium cluster (2.90, 13.57, 4.53 mm) which was posterior, medial and inferior to that of the low shift cluster (1.94, 13.92, 3.20 mm). The coordinates are referenced with respect to the mid-commissural point. Euclidean distances between the centroids were 1.68, 2.44 and 3.59 mm, respectively for low-medium, medium-large and low-large shift clusters. We found similar trends for the positions of the stimulation maps. The Euclidian distance between the highest probability locations on the low and medium-large shift maps was 4.06 mm. Conclusion The effect of brain shift in deep brain stimulation (DBS) surgery has been demonstrated using intra-operative somatotopy recordings as well as stimulation response data. The results not only indicate that considerable brain shift happens before micro-electrode recordings in DBS but also that brain shift affects the creation of accurate functional atlases. Therefore, care must be taken when building and using such atlases of intra-operative data and also when using intra-operative data to validate anatomical atlases. PMID:20033503

  1. Shift and rotation invariant photorefractive crystal-based associative memory

    NASA Astrophysics Data System (ADS)

    Uang, Chii-Maw; Lin, Wei-Feng; Lu, Ming-Huei; Lu, Guowen; Lu, Mingzhe

    1995-08-01

    A shift and rotation invariant photorefractive (PR) crystal based associative memory is addressed. The proposed associative memory has three layers: the feature extraction, inner- product, and output mapping layers. The feature extraction is performed by expanding an input object into a set of circular harmonic expansions (CHE) in the Fourier domain to acquire both the shift and rotation invariant properties. The inner product operation is performed by taking the advantage of Bragg diffraction of the bulky PR-crystal. The output mapping is achieved by using the massive storage capacity of the PR-crystal. In the training process, memories are stored in another PR-crystal by using the wavelength multiplexing technique. During the recall process, the output from the winner-take-all processor decides which wavelength should be used to read out the memory from the PR-crystal.

  2. Topology of Neutral Hydrogen within the Small Magellanic Cloud

    NASA Astrophysics Data System (ADS)

    Chepurnov, A.; Gordon, J.; Lazarian, A.; Stanimirovic, S.

    2008-12-01

    In this paper, genus statistics have been applied to an H I column density map of the Small Magellanic Cloud in order to study its topology. To learn how topology changes with the scale of the system, we provide topology studies for column density maps at varying resolutions. To evaluate the statistical error of the genus, we randomly reassign the phases of the Fourier modes while keeping the amplitudes. We find that at the smallest scales studied (40 pc <= λ <= 80 pc), the genus shift is negative in all regions, implying a clump topology. At the larger scales (110 pc <= λ <= 250 pc), the topology shift is detected to be negative (a "meatball" topology) in four cases and positive (a "swiss cheese" topology) in two cases. In four regions, there is no statistically significant topology shift at large scales.

  3. Kinematics and eye-head coordination of gaze shifts evoked from different sites in the superior colliculus of the cat.

    PubMed

    Guillaume, Alain; Pélisson, Denis

    2006-12-15

    Shifting gaze requires precise coordination of eye and head movements. It is clear that the superior colliculus (SC) is involved with saccadic gaze shifts. Here we investigate its role in controlling both eye and head movements during gaze shifts. Gaze shifts of the same amplitude can be evoked from different SC sites by controlled electrical microstimulation. To describe how the SC coordinates the eye and the head, we compare the characteristics of these amplitude-matched gaze shifts evoked from different SC sites. We show that matched amplitude gaze shifts elicited from progressively more caudal sites are progressively slower and associated with a greater head contribution. Stimulation at more caudal SC sites decreased the peak velocity of the eye but not of the head, suggesting that the lower peak gaze velocity for the caudal sites is due to the increased contribution of the slower-moving head. Eye-head coordination across the SC motor map is also indicated by the relative latencies of the eye and head movements. For some amplitudes of gaze shift, rostral stimulation evoked eye movement before head movement, whereas this reversed with caudal stimulation, which caused the head to move before the eyes. These results show that gaze shifts of similar amplitude evoked from different SC sites are produced with different kinematics and coordination of eye and head movements. In other words, gaze shifts evoked from different SC sites follow different amplitude-velocity curves, with different eye-head contributions. These findings shed light on mechanisms used by the central nervous system to translate a high-level motor representation (a desired gaze displacement on the SC map) into motor commands appropriate for the involved body segments (the eye and the head).

  4. A Tectonic Shift in Global Higher Education

    ERIC Educational Resources Information Center

    Daniel, John; Kanwar, Asha; Uvalic-Trumbic, Stamenka

    2006-01-01

    Europeans lament that their universities are lagging behind those in the United States, while Americans worry that their academic leadership is threatened by complacency. Both groups, however, are missing the tectonic shift that will transform the map of higher education worldwide--the growth of universities in the developing world. Spreading…

  5. Evidence of niche shift and global invasion potential of the tawny crazy ant, Nylanderia fulva

    USDA-ARS?s Scientific Manuscript database

    Analysis of an invasive species’ niche shift between native and introduced ranges, along with potential distribution maps, can provide valuable information about its invasive potential. The tawny crazy ant, Nylanderia fulva, is a rapidly emerging and economically important invasive species in the so...

  6. Crystal identification for a dual-layer-offset LYSO based PET system via Lu-176 background radiation and mean shift algorithm

    NASA Astrophysics Data System (ADS)

    Wei, Qingyang; Ma, Tianyu; Xu, Tianpeng; Zeng, Ming; Gu, Yu; Dai, Tiantian; Liu, Yaqiang

    2018-01-01

    Modern positron emission tomography (PET) detectors are made from pixelated scintillation crystal arrays and readout by Anger logic. The interaction position of the gamma-ray should be assigned to a crystal using a crystal position map or look-up table. Crystal identification is a critical procedure for pixelated PET systems. In this paper, we propose a novel crystal identification method for a dual-layer-offset LYSO based animal PET system via Lu-176 background radiation and mean shift algorithm. Single photon event data of the Lu-176 background radiation are acquired in list-mode for 3 h to generate a single photon flood map (SPFM). Coincidence events are obtained from the same data using time information to generate a coincidence flood map (CFM). The CFM is used to identify the peaks of the inner layer using the mean shift algorithm. The response of the inner layer is deducted from the SPFM by subtracting CFM. Then, the peaks of the outer layer are also identified using the mean shift algorithm. The automatically identified peaks are manually inspected by a graphical user interface program. Finally, a crystal position map is generated using a distance criterion based on these peaks. The proposed method is verified on the animal PET system with 48 detector blocks on a laptop with an Intel i7-5500U processor. The total runtime for whole system peak identification is 67.9 s. Results show that the automatic crystal identification has 99.98% and 99.09% accuracy for the peaks of the inner and outer layers of the whole system respectively. In conclusion, the proposed method is suitable for the dual-layer-offset lutetium based PET system to perform crystal identification instead of external radiation sources.

  7. Sensitivity in error detection of patient specific QA tools for IMRT plans

    NASA Astrophysics Data System (ADS)

    Lat, S. Z.; Suriyapee, S.; Sanghangthum, T.

    2016-03-01

    The high complexity of dose calculation in treatment planning and accurate delivery of IMRT plan need high precision of verification method. The purpose of this study is to investigate error detection capability of patient specific QA tools for IMRT plans. The two H&N and two prostate IMRT plans with MapCHECK2 and portal dosimetry QA tools were studied. Measurements were undertaken for original and modified plans with errors introduced. The intentional errors composed of prescribed dose (±2 to ±6%) and position shifting in X-axis and Y-axis (±1 to ±5mm). After measurement, gamma pass between original and modified plans were compared. The average gamma pass for original H&N and prostate plans were 98.3% and 100% for MapCHECK2 and 95.9% and 99.8% for portal dosimetry, respectively. In H&N plan, MapCHECK2 can detect position shift errors starting from 3mm while portal dosimetry can detect errors started from 2mm. Both devices showed similar sensitivity in detection of position shift error in prostate plan. For H&N plan, MapCHECK2 can detect dose errors starting at ±4%, whereas portal dosimetry can detect from ±2%. For prostate plan, both devices can identify dose errors starting from ±4%. Sensitivity of error detection depends on type of errors and plan complexity.

  8. Using 15N-Ammonium to Characterise and Map Potassium Binding Sites in Proteins by NMR Spectroscopy

    PubMed Central

    Werbeck, Nicolas D; Kirkpatrick, John; Reinstein, Jochen; Hansen, D Flemming

    2014-01-01

    A variety of enzymes are activated by the binding of potassium ions. The potassium binding sites of these enzymes are very specific, but ammonium ions can often replace potassium ions in vitro because of their similar ionic radii. In these cases, ammonium can be used as a proxy for potassium to characterise potassium binding sites in enzymes: the 1H,15N spin-pair of enzyme-bound 15NH4+ can be probed by 15N-edited heteronuclear NMR experiments. Here, we demonstrate the use of NMR spectroscopy to characterise binding of ammonium ions to two different enzymes: human histone deacetylase 8 (HDAC8), which is activated allosterically by potassium, and the bacterial Hsp70 homologue DnaK, for which potassium is an integral part of the active site. Ammonium activates both enzymes in a similar way to potassium, thus supporting this non-invasive approach. Furthermore, we present an approach to map the observed binding site onto the structure of HDAC8. Our method for mapping the binding site is general and does not require chemical shift assignment of the enzyme resonances. PMID:24520048

  9. Preliminary results from the COBE differential microwave radiometers - Large angular scale isotropy of the cosmic microwave background

    NASA Technical Reports Server (NTRS)

    Smoot, G. F.; Aymon, J.; Bennett, C. L.; Kogut, A.; Backus, C.

    1991-01-01

    Preliminary but precise micowave maps are presented of the sky, and thus of the early universe, derived as the first results from the Differential Microwave Radiometers experiment aboard COBE. The dipole anisotropy attributed to the motion of the solar system with respect to the CMB reference frame shows strongly in all six sky maps and is consistent with a Doppler-shifted thermal spectrum. The best-fitted dipole has amplitude 3.3 + or - 0.2 mK in the direction (alpha, delta) = 11.2 h + or - 0.2 h, -7 deg + or - 2 deg (J2000) or (l,b) = 265 deg + or - 2 deg, 48 deg + or - 2 deg. There is no clear evidence in the maps for any other large angular-scale feature. Limits on Delta T/T0 of 3 x 10 to the -5th (T0 = 2.735 K), 4 x 10 to the -5th, and 4 x 10 to the -5th are found for the rms quadrupole amplitude, monochromatic fluctuations, and Gaussian fluctuations, respectively. These measurements place the most severe constraints to date on many potential physical processes in the early universe.

  10. Using ultrasound CBE imaging without echo shift compensation for temperature estimation.

    PubMed

    Tsui, Po-Hsiang; Chien, Yu-Ting; Liu, Hao-Li; Shu, Yu-Chen; Chen, Wen-Shiang

    2012-09-01

    Clinical trials have demonstrated that hyperthermia improves cancer treatments. Previous studies developed ultrasound temperature imaging methods, based on the changes in backscattered energy (CBE), to monitor temperature variations during hyperthermia. Echo shift, induced by increasing temperature, contaminates the CBE image, and its tracking and compensation should normally ensure that estimations of CBE at each pixel are correct. To obtain a simplified algorithm that would allow real-time computation of CBE images, this study evaluated the usefulness of CBE imaging without echo shift compensation in detecting distributions in temperature. Experiments on phantoms, using different scatterer concentrations, and porcine livers were conducted to acquire raw backscattered data at temperatures ranging from 37°C to 45°C. Tissue samples of pork tenderloin were ablated in vitro by microwave irradiation to evaluate the feasibility of using the CBE image without compensation to monitor tissue ablation. CBE image construction was based on a ratio map obtained from the envelope image divided by the reference envelope image at 37°C. The experimental results demonstrated that the CBE image obtained without echo shift compensation has the ability to estimate temperature variations induced during uniform heating or tissue ablation. The magnitude of the CBE as a function of temperature obtained without compensation is stronger than that with compensation, implying that the CBE image without compensation has a better sensitivity to detect temperature. These findings suggest that echo shift tracking and compensation may be unnecessary in practice, thus simplifying the algorithm required to implement real-time CBE imaging. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. Molecular mapping of chromosomes 17 and X. Progress report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barker, D.F.

    1989-12-31

    The basic aims of this project are the construction of high density genetic maps of chromosomes 17 and X and the utilization of these maps for the subsequent isolation of a set of physically overlapping DNA segment clones. The strategy depends on the utilization of chromosome specific libraries of small (1--15 kb) segments from each of the two chromosomes. Since the time of submission of our previous progress report, we have refined the genetic map of markers which we had previously isolated for chromosome 17. We have completed our genetic mapping in CEPH reference and NF1 families of 15 markersmore » in the pericentric region of chromosome 17. Physical mapping results with three probes, were shown be in very close genetic proximity to the NF1 gene, with respect to two translocation breakpoints which disrupt the activity of the gene. All three of the probes were found to lie between the centromere and the most proximal translocation breakpoint, providing important genetic markers proximal to the NF1 gene. Our primary focus has shifted to the X chromosome. We have isolated an additional 30 polymorphic markers, bringing the total number we have isolated to over 80. We have invested substantial effort in characterizing the polymorphisms at each of these loci and constructed plasmid subclones which reveal the polymorphisms for nearly all of the loci. These subclones are of practical value in that they produce simpler and stronger patterns on human genomic Southern blots, thus improving the efficiency of the genetic mapping experiments. These subclones may also be of value for deriving DNA sequence information at each locus, necessary for establishing polymerase chain reaction primers specific for each locus. Such information would allow the use of each locus as a sequence tagged site.« less

  12. Molecular mapping of chromosomes 17 and X

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barker, D.F.

    1989-01-01

    The basic aims of this project are the construction of high density genetic maps of chromosomes 17 and X and the utilization of these maps for the subsequent isolation of a set of physically overlapping DNA segment clones. The strategy depends on the utilization of chromosome specific libraries of small (1--15 kb) segments from each of the two chromosomes. Since the time of submission of our previous progress report, we have refined the genetic map of markers which we had previously isolated for chromosome 17. We have completed our genetic mapping in CEPH reference and NF1 families of 15 markersmore » in the pericentric region of chromosome 17. Physical mapping results with three probes, were shown be in very close genetic proximity to the NF1 gene, with respect to two translocation breakpoints which disrupt the activity of the gene. All three of the probes were found to lie between the centromere and the most proximal translocation breakpoint, providing important genetic markers proximal to the NF1 gene. Our primary focus has shifted to the X chromosome. We have isolated an additional 30 polymorphic markers, bringing the total number we have isolated to over 80. We have invested substantial effort in characterizing the polymorphisms at each of these loci and constructed plasmid subclones which reveal the polymorphisms for nearly all of the loci. These subclones are of practical value in that they produce simpler and stronger patterns on human genomic Southern blots, thus improving the efficiency of the genetic mapping experiments. These subclones may also be of value for deriving DNA sequence information at each locus, necessary for establishing polymerase chain reaction primers specific for each locus. Such information would allow the use of each locus as a sequence tagged site.« less

  13. Detection of edge component of threading dislocations in GaN by Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Kokubo, Nobuhiko; Tsunooka, Yosuke; Fujie, Fumihiro; Ohara, Junji; Hara, Kazukuni; Onda, Shoichi; Yamada, Hisashi; Shimizu, Mitsuaki; Harada, Shunta; Tagawa, Miho; Ujihara, Toru

    2018-06-01

    We succeeded in measuring the density and direction of the edge component of threading dislocations (TDs) in c-plane (0001) GaN by micro-Raman spectroscopy mapping. In the micro-Raman spectroscopy mapping of the E2 H peak shift between 567.85 and 567.75 cm‑1, six different contrast images are observed toward directions of < 1\\bar{1}00> . By comparing X-ray topography and etch pit images, the E2 H peak shift is observed where the edge component of TDs exists. In contrast, the E2 H peak is not observed where the screw component of TDs exists.

  14. Pattern recognition neural-net by spatial mapping of biology visual field

    NASA Astrophysics Data System (ADS)

    Lin, Xin; Mori, Masahiko

    2000-05-01

    The method of spatial mapping in biology vision field is applied to artificial neural networks for pattern recognition. By the coordinate transform that is called the complex-logarithm mapping and Fourier transform, the input images are transformed into scale- rotation- and shift- invariant patterns, and then fed into a multilayer neural network for learning and recognition. The results of computer simulation and an optical experimental system are described.

  15. Evidence against integration of spatial maps in humans.

    PubMed

    Sturz, Bradley R; Bodily, Kent D; Katz, Jeffrey S

    2006-07-01

    A dynamic 3-D virtual environment was constructed for humans as an open-field analogue of Blaisdell and Cook's (2005) pigeon foraging task to determine if humans, like pigeons, were capable of integrating separate spatial maps. Participants used keyboard keys and a mouse to search for a hidden goal in a 4x4 grid of raised cups. During Phase 1 training, a goal was consistently located between two landmarks (Map 1: blue T and red L). During Phase 2 training, a goal was consistently located down and left of a single landmark (Map 2: blue T). Transfer trials were then conducted in which participants were required to make choices in the presence of the red L alone. Cup choices during transfer assessed participants' strategies: association (from Map 1), generalization (from Map 2), or integration (combining Map 1 and 2). During transfer, cup choices increased to a location which suggested an integration strategy and was consistent with results obtained with pigeons. However, additional analyses of the human data suggested participants initially used a generalization strategy followed by a progressive shift in search behavior away from the red L. This shift in search behavior during transfer was responsible for the changes in cup choices across transfer trials and was confirmed by a control condition. These new analyses offer an alternative explanation to the spatial integration account proposed for pigeons.

  16. Implementation of the NMR CHEmical Shift Covariance Analysis (CHESCA): A Chemical Biologist's Approach to Allostery.

    PubMed

    Boulton, Stephen; Selvaratnam, Rajeevan; Ahmed, Rashik; Melacini, Giuseppe

    2018-01-01

    Mapping allosteric sites is emerging as one of the central challenges in physiology, pathology, and pharmacology. Nuclear Magnetic Resonance (NMR) spectroscopy is ideally suited to map allosteric sites, given its ability to sense at atomic resolution the dynamics underlying allostery. Here, we focus specifically on the NMR CHEmical Shift Covariance Analysis (CHESCA), in which allosteric systems are interrogated through a targeted library of perturbations (e.g., mutations and/or analogs of the allosteric effector ligand). The atomic resolution readout for the response to such perturbation library is provided by NMR chemical shifts. These are then subject to statistical correlation and covariance analyses resulting in clusters of allosterically coupled residues that exhibit concerted responses to the common set of perturbations. This chapter provides a description of how each step in the CHESCA is implemented, starting from the selection of the perturbation library and ending with an overview of different clustering options.

  17. Robust dynamic 3-D measurements with motion-compensated phase-shifting profilometry

    NASA Astrophysics Data System (ADS)

    Feng, Shijie; Zuo, Chao; Tao, Tianyang; Hu, Yan; Zhang, Minliang; Chen, Qian; Gu, Guohua

    2018-04-01

    Phase-shifting profilometry (PSP) is a widely used approach to high-accuracy three-dimensional shape measurements. However, when it comes to moving objects, phase errors induced by the movement often result in severe artifacts even though a high-speed camera is in use. From our observations, there are three kinds of motion artifacts: motion ripples, motion-induced phase unwrapping errors, and motion outliers. We present a novel motion-compensated PSP to remove the artifacts for dynamic measurements of rigid objects. The phase error of motion ripples is analyzed for the N-step phase-shifting algorithm and is compensated using the statistical nature of the fringes. The phase unwrapping errors are corrected exploiting adjacent reliable pixels, and the outliers are removed by comparing the original phase map with a smoothed phase map. Compared with the three-step PSP, our method can improve the accuracy by more than 95% for objects in motion.

  18. Spatial problem-solving strategies of middle school students: Wayfinding with geographic information systems

    NASA Astrophysics Data System (ADS)

    Wigglesworth, John C.

    2000-06-01

    Geographic Information Systems (GIS) is a powerful computer software package that emphasizes the use of maps and the management of spatially referenced environmental data archived in a systems data base. Professional applications of GIS have been in place since the 1980's, but only recently has GIS gained significant attention in the K--12 classroom. Students using GIS are able to manipulate and query data in order to solve all manners of spatial problems. Very few studies have examined how this technological innovation can support classroom learning. In particular, there has been little research on how experience in using the software correlates with a child's spatial cognition and his/her ability to understand spatial relationships. This study investigates the strategies used by middle school students to solve a wayfinding (route-finding) problem using the ArcView GIS software. The research design combined an individual background questionnaire, results from the Group Assessment of Logical Thinking (GALT) test, and analysis of reflective think-aloud sessions to define the characteristics of the strategies students' used to solve this particular class of spatial problem. Three uniquely different spatial problem solving strategies were identified. Visual/Concrete Wayfinders used a highly visual strategy; Logical/Abstract Wayfinders used GIS software tools to apply a more analytical and systematic approach; Transitional Wayfinders used an approach that showed evidence of one that was shifting from a visual strategy to one that was more analytical. The triangulation of data sources indicates that this progression of wayfinding strategy can be correlated both to Piagetian stages of logical thought and to experience with the use of maps. These findings suggest that GIS teachers must be aware that their students' performance will lie on a continuum that is based on cognitive development, spatial ability, and prior experience with maps. To be most effective, GIS teaching strategies and curriculum development should also represent a progression that correlates to the learners' current skills and experience.

  19. Redshift Measurement and Spectral Classification for eBoss Galaxies with the Redmonster Software

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hutchinson, Timothy A.; Bolton, Adam S.; Dawson, Kyle S.

    “Cosmological redshift surveys” are experiments conducted with astronomical telescopes, imagers, and spectrographs, which map the three-dimensional structure of the universe on the largest scales. These maps are delineated by the positions of galaxies, quasars, and intergalactic hydrogen clouds. When interpreted in the context of Einstein’s theory of gravity, these maps can be used to infer the nature of the contents of the universe, including the mysterious “dark energy” that is driving the expansion of the universe to accelerate. While the directional positions of galaxies and other objects can be measured directly in images of the sky, the third dimension ofmore » their position (i.e., their distance from the Earth and the Milky Way Galaxy) must be measured by spectrographs that distribute their light as a function of frequency, enabling a measurement of their cosmological Doppler shift (or “redshift”), which serves as an observable proxy for distance. The largest cosmological redshift surveys, such as the “eBOSS” experiment of the fourth Sloan Digital Sky Survey, collect spectroscopic data for hundreds of thousands to millions of galaxies. Future experiments such as the Dark Energy Spectroscopic Instrument will in turn collect tens of millions of spectra. To be feasible, redshift measurement methods in datasets of this scale must be made with automated software. This paper describes the algorithms, astrophysical templates, and implementation of a new redshift measurement software package that is optimized to run on large numbers of spectra with relatively low signal-to-noise ratio, typical of the most ambitious current and future cosmological redshift surveys. The software is demonstrated on spectroscopic data from the eBOSS survey, with performance that meets the scientific requirements of that experiment. The software is implemented in a general framework that will allow application to spectra from the DESI project in the future.« less

  20. Redshift Measurement and Spectral Classification for eBoss Galaxies with the Redmonster Software

    DOE PAGES

    Hutchinson, Timothy A.; Bolton, Adam S.; Dawson, Kyle S.; ...

    2016-12-02

    “Cosmological redshift surveys” are experiments conducted with astronomical telescopes, imagers, and spectrographs, which map the three-dimensional structure of the universe on the largest scales. These maps are delineated by the positions of galaxies, quasars, and intergalactic hydrogen clouds. When interpreted in the context of Einstein’s theory of gravity, these maps can be used to infer the nature of the contents of the universe, including the mysterious “dark energy” that is driving the expansion of the universe to accelerate. While the directional positions of galaxies and other objects can be measured directly in images of the sky, the third dimension ofmore » their position (i.e., their distance from the Earth and the Milky Way Galaxy) must be measured by spectrographs that distribute their light as a function of frequency, enabling a measurement of their cosmological Doppler shift (or “redshift”), which serves as an observable proxy for distance. The largest cosmological redshift surveys, such as the “eBOSS” experiment of the fourth Sloan Digital Sky Survey, collect spectroscopic data for hundreds of thousands to millions of galaxies. Future experiments such as the Dark Energy Spectroscopic Instrument will in turn collect tens of millions of spectra. To be feasible, redshift measurement methods in datasets of this scale must be made with automated software. This paper describes the algorithms, astrophysical templates, and implementation of a new redshift measurement software package that is optimized to run on large numbers of spectra with relatively low signal-to-noise ratio, typical of the most ambitious current and future cosmological redshift surveys. The software is demonstrated on spectroscopic data from the eBOSS survey, with performance that meets the scientific requirements of that experiment. The software is implemented in a general framework that will allow application to spectra from the DESI project in the future.« less

  1. On the instability and constraints of the interaction between number representation and spatial attention in healthy humans: A concise review of the literature and new experimental evidence.

    PubMed

    Fattorini, E; Pinto, M; Merola, S; D'Onofrio, M; Doricchi, F

    2016-01-01

    The relationship between number and space representation is still one of the most debated topics in studies of mathematical cognition. Here we offer a concise review of two important behavioral effects that have pointed out the use of a spatially left-to-right oriented mental number line (MNL) in healthy participants: the SNARC effect and the attentional SNARC effect (Att-SNARC). Following a brief summary of seminal investigations on the introspective properties of the MNL, we review recent empirical evidence and theories on the functional origin of the SNARC effect, where upon left/right response choices faster reaction times are found for small numbers with left-side responses and for large numbers with right-side responses. Then we offer a summary of the studies that have investigated whether the mere perception of visual Arabic numbers presented at central fixation can engender spatially congruent lateral shifts of attention, ie, leftward for small numbers and rightward for large ones, ie, the Att-SNARC effect. Finally, we summarize four experiments that tested whether the Att-SNARC depends on an active rather than passive processing of centrally presented digit cues. In line with other recent studies, these experiment do not replicate the original Att-SNARC and show that the mere perception of Arabic numerals does not trigger automatic shifts of attention. These shifts are instead found when the task requires the explicit left/right spatial coding of digit cues, ie, Spatial Att-SNARC (Fattorini et al., 2015b). Nonetheless, the reliability of the Spatial Att-SNARC effect seems not as strong as that of conventional SNARC effects where left/right codes are mapped onto responses rather than directly mapped on digit cues. Comparing the magnitude of digits to a numerical reference, ie, "5," also produced a Magnitude Comparison Att-SNARC that was weaker than the spatial one. However, the reliability of this Magnitude Comparison Att-SNARC should be considered with caution because, like in a study by Zanolie and Pecher (2014), we recently failed to replicate this effect in a separate behavioral-event-related potentials study in preparation (Fattorini et al., 2015a). All together the results from the present series of experiments support the hypothesis that spatial coding is not an intrinsic part of number representation and that number-space interaction is determined by the use of stimulus- or response-related spatial codes in the task at hand. © 2016 Elsevier B.V. All rights reserved.

  2. Analysis of large-scale gene expression data.

    PubMed

    Sherlock, G

    2000-04-01

    The advent of cDNA and oligonucleotide microarray technologies has led to a paradigm shift in biological investigation, such that the bottleneck in research is shifting from data generation to data analysis. Hierarchical clustering, divisive clustering, self-organizing maps and k-means clustering have all been recently used to make sense of this mass of data.

  3. Suitability of the echo-time-shift method as laboratory standard for thermal ultrasound dosimetry

    NASA Astrophysics Data System (ADS)

    Fuhrmann, Tina; Georg, Olga; Haller, Julian; Jenderka, Klaus-Vitold

    2017-03-01

    Ultrasound therapy is a promising, non-invasive application with potential to significantly improve cancer therapies like surgery, viro- or immunotherapy. This therapy needs faster, cheaper and more easy-to-handle quality assurance tools for therapy devices as well as possibilities to verify treatment plans and for dosimetry. This limits comparability and safety of treatments. Accurate spatial and temporal temperature maps could be used to overcome these shortcomings. In this contribution first results of suitability and accuracy investigations of the echo-time-shift method for two-dimensional temperature mapping during and after sonication are presented. The analysis methods used to calculate time-shifts were a discrete frame-to-frame and a discrete frame-to-base-frame algorithm as well as a sigmoid fit for temperature calculation. In the future accuracy could be significantly enhanced by using continuous methods for time-shift calculation. Further improvements can be achieved by improving filtering algorithms and interpolation of sampled diagnostic ultrasound data. It might be a comparatively accurate, fast and affordable method for laboratory and clinical quality control.

  4. Win-stay and win-shift lever-press strategies in an appetitively reinforced task for rats.

    PubMed

    Reed, Phil

    2016-12-01

    Two experiments examined acquisition of win-stay, win-shift, lose-stay, and lose-shift rules by which hungry rats could earn food reinforcement. In Experiment 1, two groups of rats were trained in a two-lever operant task that required them to follow either a win-stay/lose-shift or a win-shift/lose-stay contingency. The rates of acquisition of the individual rules within each contingency differed: lose-shift and lose-stay rules were acquired faster than win-stay and win-shift rules. Contrary to a number of previous reports, the win-shift rule was acquired less rapidly than any of the other rules. In Experiment 2, the four rules were taught separately, but subjects still acquired the win-shift rule more slowly than any of the other rules.

  5. Revealing Nanostructures through Plasmon Polarimetry.

    PubMed

    Kleemann, Marie-Elena; Mertens, Jan; Zheng, Xuezhi; Cormier, Sean; Turek, Vladimir; Benz, Felix; Chikkaraddy, Rohit; Deacon, William; Lombardi, Anna; Moshchalkov, Victor V; Vandenbosch, Guy A E; Baumberg, Jeremy J

    2017-01-24

    Polarized optical dark-field spectroscopy is shown to be a versatile noninvasive probe of plasmonic structures that trap light to the nanoscale. Clear spectral polarization splittings are found to be directly related to the asymmetric morphology of nanocavities formed between faceted gold nanoparticles and an underlying gold substrate. Both experiment and simulation show the influence of geometry on the coupled system, with spectral shifts Δλ = 3 nm from single atoms. Analytical models allow us to identify the split resonances as transverse cavity modes, tightly confined to the nanogap. The direct correlation of resonance splitting with atomistic morphology allows mapping of subnanometre structures, which is crucial for progress in extreme nano-optics involving chemistry, nanophotonics, and quantum devices.

  6. Students' educational experiences and interaction with residents on night shifts.

    PubMed

    Schiller, Jocelyn; Sokoloff, Max; Tendhar, Chosang; Schmidt, John; Christner, Jennifer

    2017-08-01

    The purpose of this mixed-methods study was to investigate whether increased night shifts for students on paediatric rotations had any negative impact on their overall quality of educational experiences in light of the implementation of duty-hour restrictions. Both quantitative and qualitative data were collected from 30 students on paediatric rotations during the academic year 2011/12. Students completed two questionnaires, one in response to their experiences during the day shifts and another in response to their experiences during the night shifts. Only 25 cases were retained for the final analyses. The non-parametric Wilcoxon signed-rank test was used to analyse the quantitative data, and constant comparative thematic analyses, as described by Creswell, were used to analyse the qualitative data. [Do] increased nights shifts for students … [have] any negative impact on their overall quality of educational experiences[?] RESULTS: The results indicated that students' perceived quality of experiences during the night shifts was greater, compared with their day shifts. Students reported having more time to socialise during the night shifts. They further reported that informal ways of learning, such as impromptu teaching and spontaneous discussions on clinical problems, were more beneficial, and these often occurred in abundance during the night shifts as opposed to the scheduled didactic teaching sessions that occur during the day shifts. This study documented many unanticipated benefits of night shifts. The feeling of cohesiveness of the night team deserves further exploration, as this can be linked to better performance outcomes. More consideration should be given to implementing night shifts as a regular feature of clerkships. © 2016 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

  7. A modular architecture for transparent computation in recurrent neural networks.

    PubMed

    Carmantini, Giovanni S; Beim Graben, Peter; Desroches, Mathieu; Rodrigues, Serafim

    2017-01-01

    Computation is classically studied in terms of automata, formal languages and algorithms; yet, the relation between neural dynamics and symbolic representations and operations is still unclear in traditional eliminative connectionism. Therefore, we suggest a unique perspective on this central issue, to which we would like to refer as transparent connectionism, by proposing accounts of how symbolic computation can be implemented in neural substrates. In this study we first introduce a new model of dynamics on a symbolic space, the versatile shift, showing that it supports the real-time simulation of a range of automata. We then show that the Gödelization of versatile shifts defines nonlinear dynamical automata, dynamical systems evolving on a vectorial space. Finally, we present a mapping between nonlinear dynamical automata and recurrent artificial neural networks. The mapping defines an architecture characterized by its granular modularity, where data, symbolic operations and their control are not only distinguishable in activation space, but also spatially localizable in the network itself, while maintaining a distributed encoding of symbolic representations. The resulting networks simulate automata in real-time and are programmed directly, in the absence of network training. To discuss the unique characteristics of the architecture and their consequences, we present two examples: (i) the design of a Central Pattern Generator from a finite-state locomotive controller, and (ii) the creation of a network simulating a system of interactive automata that supports the parsing of garden-path sentences as investigated in psycholinguistics experiments. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. The change in spatial distribution of upper trapezius muscle activity is correlated to contraction duration.

    PubMed

    Farina, Dario; Leclerc, Frédéric; Arendt-Nielsen, Lars; Buttelli, Olivier; Madeleine, Pascal

    2008-02-01

    The aim of the study was to confirm the hypothesis that the longer a contraction is sustained, the larger are the changes in the spatial distribution of muscle activity. For this purpose, surface electromyographic (EMG) signals were recorded with a 13 x 5 grid of electrodes from the upper trapezius muscle of 11 healthy male subjects during static contractions with shoulders 90 degrees abducted until endurance. The entropy (degree of uniformity) and center of gravity of the EMG root mean square map were computed to assess spatial inhomogeneity in muscle activation and changes over time in EMG amplitude spatial distribution. At the endurance time, entropy decreased (mean+/-SD, percent change 2.0+/-1.6%; P<0.0001) and the center of gravity moved in the cranial direction (shift 11.2+/-6.1mm; P<0.0001) with respect to the beginning of the contraction. The shift in the center of gravity was positively correlated with endurance time (R(2)=0.46, P<0.05), thus subjects with larger shift in the activity map showed longer endurance time. The percent variation in average (over the grid) root mean square was positively correlated with the shift in the center of gravity (R(2)=0.51, P<0.05). Moreover, the shift in the center of gravity was negatively correlated to both initial and final (at the endurance) entropy (R(2)=0.54 and R(2)=0.56, respectively; P<0.01 in both cases), indicating that subjects with less uniform root mean square maps had larger shift of the center of gravity over time. The spatial changes in root mean square EMG were likely due to spatially-dependent changes in motor unit activation during the sustained contraction. It was concluded that the changes in spatial muscle activity distribution play a role in the ability to maintain a static contraction.

  9. Looking at Op Art from a computational viewpoint.

    PubMed

    Zanker, Johannes M

    2004-01-01

    Arts history tells an exciting story about repeated attempts to represent features that are crucial for the understanding of our environment and which, at the same time, go beyond the inherently two-dimensional nature of a flat painting surface: depth and motion. In the twentieth century, Op artists such as Bridget Riley began to experiment with simple black and white patterns that do not represent motion in an artistic way but actually create vivid dynamic illusions in static pictures. The cause of motion illusions in such paintings is still a matter of debate. The role of involuntary eye movements in this phenomenon is studied here with a computational approach. The possible consequences of shifting the retinal image of synthetic wave gratings, dubbed as 'riloids', were analysed by a two-dimensional array of motion detectors (2DMD model), which generates response maps representing the spatial distribution of motion signals generated by such a stimulus. For a two-frame sequence reflecting a saccadic displacement, these motion signal maps contain extended patches in which local directions change only little. These directions, however, do not usually precisely correspond to the direction of pattern displacement that can be expected from the geometry of the curved gratings as an instance of the so-called 'aperture problem'. The patchy structure of the simulated motion detector response to the displacement of riloids resembles the motion illusion, which is not perceived as a coherent shift of the whole pattern but as a wobbling and jazzing of ill-defined regions. Although other explanations are not excluded, this might support the view that the puzzle of Op Art motion illusions could potentially have an almost trivial solution in terms of small involuntary eye movement leading to image shifts that are picked up by well-known motion detectors in the early visual system. This view can have further consequences for our understanding of how the human visual system usually compensates for eye movements, in order to let us perceive a stable world despite continuous image shifts generated by gaze instability.

  10. Neutrally buoyant tracers in hydrogeophysics: Field demonstration in fractured rock

    NASA Astrophysics Data System (ADS)

    Shakas, Alexis; Linde, Niklas; Baron, Ludovic; Selker, John; Gerard, Marie-Françoise; Lavenant, Nicolas; Bour, Olivier; Le Borgne, Tanguy

    2017-04-01

    Electrical and electromagnetic methods are extensively used to map electrically conductive tracers within hydrogeologic systems. Often, the tracers used consist of dissolved salt in water, leading to a denser mixture than the ambient formation water. Density effects are often ignored and rarely modeled but can dramatically affect transport behavior and introduce dynamics that are unrepresentative of the response obtained with classical tracers (e.g., uranine). We introduce a neutrally buoyant tracer consisting of a mixture of salt, water, and ethanol and monitor its movement during push-pull experiments in a fractured rock aquifer using ground-penetrating radar. Our results indicate a largely reversible transport process and agree with uranine-based push-pull experiments at the site, which is in contrast to results obtained using dense saline tracers. We argue that a shift toward neutrally buoyant tracers in both porous and fractured media would advance hydrogeophysical research and enhance its utility in hydrogeology.

  11. Alleviating artifacts in 1H MRI thermometry by single scan spatiotemporal encoding.

    PubMed

    Schmidt, Rita; Frydman, Lucio

    2013-10-01

    Recent years have seen an increased interest in combining MRI thermometry with devices capable of destroying malignancies by heat ablation. Expected from the MR protocols are accurate and fast thermal characterizations, providing real time feedback on restricted tissue volumes and/or rapidly moving organs like liver. This article explores the potential advantages of relying on spatiotemporally encoded (SPEN) sequences for retrieving real-time thermometric images based on the water's proton resonance frequency (PRF) shifts. Hybrid spatiotemporal/k-space encoding single-scan MRI experiments were implemented on animal and human scanners, and their abilities to deliver single- and multi-slice real-time thermometric measurements based on PRF-derived phase maps in phantoms and in vivo, were compared against echo planar imaging (EPI) and gradient-echo counterparts. Under comparable acquisition conditions, SPEN exhibited advantages vis-à-vis EPI in terms of dealing with inhomogeneous magnetic field distortions, with shifts arising due to changes in the central frequency offsets, with PRF distributions, and for zooming into restricted fields-of-view without special pulse sequence provisions. This work confirms the ability of SPEN sequences, particularly when implemented under fully-refocused conditions, to exploit their built-in robustness to shift- and field-derived inhomogeneities for monitoring thermal changes in real-time under in vitro and in vivo conditions.

  12. Rate of novel host invasion affects adaptability of evolving RNA virus lineages.

    PubMed

    Morley, Valerie J; Mendiola, Sandra Y; Turner, Paul E

    2015-08-22

    Although differing rates of environmental turnover should be consequential for the dynamics of adaptive change, this idea has been rarely examined outside of theory. In particular, the importance of RNA viruses in disease emergence warrants experiments testing how differing rates of novel host invasion may impact the ability of viruses to adaptively shift onto a novel host. To test whether the rate of environmental turnover influences adaptation, we experimentally evolved 144 Sindbis virus lineages in replicated tissue-culture environments, which transitioned from being dominated by a permissive host cell type to a novel host cell type. The rate at which the novel host 'invaded' the environment varied by treatment. The fitness (growth rate) of evolved virus populations was measured on each host type, and molecular substitutions were mapped via whole genome consensus sequencing. Results showed that virus populations more consistently reached high fitness levels on the novel host when the novel host 'invaded' the environment more gradually, and gradual invasion resulted in less variable genomic outcomes. Moreover, virus populations that experienced a rapid shift onto the novel host converged upon different genotypes than populations that experienced a gradual shift onto the novel host, suggesting a strong effect of historical contingency. © 2015 The Author(s).

  13. Noncommutative mapping from the symplectic formalism

    NASA Astrophysics Data System (ADS)

    De Andrade, M. A.; Neves, C.

    2018-01-01

    Bopp's shifts will be generalized through a symplectic formalism. A special procedure, like "diagonalization," which drives the completely deformed symplectic matrix to the standard symplectic form was found as suggested by Faddeev-Jackiw. Consequently, the correspondent transformation matrix guides the mapping from commutative to noncommutative (NC) phase-space coordinates. Bopp's shifts may be directly generalized from this mapping. In this context, all the NC and scale parameters, introduced into the brackets, will be lifted to the Hamiltonian. Well-known results, obtained using ⋆-product, will be reproduced without considering that the NC parameters are small (≪1). Besides, it will be shown that different choices for NC algebra among the symplectic variables generate distinct dynamical systems, in which they may not even connect with each other, and that some of them can preserve, break, or restore the symmetry of the system. Further, we will also discuss the charge and mass rescaling in a simple model.

  14. Do we face a fourth paradigm shift in medicine--algorithms in education?

    PubMed

    Eitel, F; Kanz, K G; Hortig, E; Tesche, A

    2000-08-01

    Medicine has evolved toward rationalization since the Enlightenment, favouring quantitative measures. Now, a paradigm shift toward control through formalization can be observed in health care whose structures and processes are subjected to increasing standardization. However, educational reforms and curricula do not yet adequately respond to this shift. The aim of this article is to describe innovative approaches in medical education for adapting to these changes. The study design is a descriptive case report relying on a literature review and on a reform project's evaluation. Concept mapping is used to graphically represent relationships among concepts, i.e. defined terms from educational literature. Definitions of 'concept map', 'guideline' and 'algorithm' are presented. A prototypical algorithm for organizational decision making in the project's instructional design is shown. Evaluation results of intrinsic learning motivation are demonstrated: intrinsic learning motivation depends upon students' perception of their competence exhibiting path coefficients varying from 0.42 to 0.51. Perception of competence varies with the type of learning environment. An innovative educational format, called 'evidence-based learning (EBL)' is deduced from these findings and described here. Effects of formalization consist of structuring decision making about implementation of different learning environments or about minimizing variance in teaching or learning. Unintended effects of formalization such as implementation problems and bureaucracy are discussed. Formalized tools for designing medical education are available. Specific instructional designs influence students' learning motivation. Concept maps are suitable for controlling educational quality, thus enabling the paradigm shift in medical education.

  15. Toward best practices for developing regional connectivity maps.

    PubMed

    Beier, Paul; Spencer, Wayne; Baldwin, Robert F; McRae, Brad H

    2011-10-01

    To conserve ecological connectivity (the ability to support animal movement, gene flow, range shifts, and other ecological and evolutionary processes that require large areas), conservation professionals need coarse-grained maps to serve as decision-support tools or vision statements and fine-grained maps to prescribe site-specific interventions. To date, research has focused primarily on fine-grained maps (linkage designs) covering small areas. In contrast, we devised 7 steps to coarsely map dozens to hundreds of linkages over a large area, such as a nation, province, or ecoregion. We provide recommendations on how to perform each step on the basis of our experiences with 6 projects: California Missing Linkages (2001), Arizona Wildlife Linkage Assessment (2006), California Essential Habitat Connectivity (2010), Two Countries, One Forest (northeastern United States and southeastern Canada) (2010), Washington State Connected Landscapes (2010), and the Bhutan Biological Corridor Complex (2010). The 2 most difficult steps are mapping natural landscape blocks (areas whose conservation value derives from the species and ecological processes within them) and determining which pairs of blocks can feasibly be connected in a way that promotes conservation. Decision rules for mapping natural landscape blocks and determining which pairs of blocks to connect must reflect not only technical criteria, but also the values and priorities of stakeholders. We recommend blocks be mapped on the basis of a combination of naturalness, protection status, linear barriers, and habitat quality for selected species. We describe manual and automated procedures to identify currently functioning or restorable linkages. Once pairs of blocks have been identified, linkage polygons can be mapped by least-cost modeling, other approaches from graph theory, or individual-based movement models. The approaches we outline make assumptions explicit, have outputs that can be improved as underlying data are improved, and help implementers focus strictly on ecological connectivity. ©2011 Society for Conservation Biology.

  16. Bibliometric mapping: eight decades of analytical chemistry, with special focus on the use of mass spectrometry.

    PubMed

    Waaijer, Cathelijn J F; Palmblad, Magnus

    2015-01-01

    In this Feature we use automatic bibliometric mapping tools to visualize the history of analytical chemistry from the 1920s until the present. In particular, we have focused on the application of mass spectrometry in different fields. The analysis shows major shifts in research focus and use of mass spectrometry. We conclude by discussing the application of bibliometric mapping and visualization tools in analytical chemists' research.

  17. Investigation of BOLD fMRI Resonance Frequency Shifts and Quantitative Susceptibility Changes at 7 T

    PubMed Central

    Bianciardi, Marta; van Gelderen, Peter; Duyn, Jeff H.

    2013-01-01

    Although blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) experiments of brain activity generally rely on the magnitude of the signal, they also provide frequency information that can be derived from the phase of the signal. However, because of confounding effects of instrumental and physiological origin, BOLD related frequency information is difficult to extract and therefore rarely used. Here, we explored the use of high field (7 T) and dedicated signal processing methods to extract frequency information and use it to quantify and interpret blood oxygenation and blood volume changes. We found that optimized preprocessing improves detection of task-evoked and spontaneous changes in phase signals and resonance frequency shifts over large areas of the cortex with sensitivity comparable to that of magnitude signals. Moreover, our results suggest the feasibility of mapping BOLD quantitative susceptibility changes in at least part of the activated area and its largest draining veins. Comparison with magnitude data suggests that the observed susceptibility changes originate from neuronal activity through induced blood volume and oxygenation changes in pial and intracortical veins. Further, from frequency shifts and susceptibility values, we estimated that, relative to baseline, the fractional oxygen saturation in large vessels increased by 0.02–0.05 during stimulation, which is consistent to previously published estimates. Together, these findings demonstrate that valuable information can be derived from fMRI imaging of BOLD frequency shifts and quantitative susceptibility changes. PMID:23897623

  18. New experiments on the effect of clock shifts on homing in pigeons

    NASA Technical Reports Server (NTRS)

    Schmidt-Koenig, K.

    1972-01-01

    The effect of clock shifts as an experimental tool for predictably interfering with the homing ability of birds is discussed. Clock shifts introduce specific errors in the birds' sun azimuth compass, resulting in corresponding errors during initial orientation and possibly during orientation enroute. The effects of 6 hour and 12 hour clock shifts resulted in a 90 degree deviation and a 180 degree deviation from the initial orientation, respectively. The method for conducting the clock shift experiments and results obtained from previous experiments are described.

  19. Estimation of elasticity map of soft biological tissue mimicking phantom using laser speckle contrast analysis

    NASA Astrophysics Data System (ADS)

    Suheshkumar Singh, M.; Rajan, K.; Vasu, R. M.

    2011-05-01

    Scattering of coherent light from scattering particles causes phase shift to the scattered light. The interference of unscattered and scattered light causes the formation of speckles. When the scattering particles, under the influence of an ultrasound (US) pressure wave, vibrate, the phase shift fluctuates, thereby causing fluctuation in speckle intensity. We use the laser speckle contrast analysis (LSCA) to reconstruct a map of the elastic property (Young's modulus) of soft tissue-mimicking phantom. The displacement of the scatters is inversely related to the Young's modulus of the medium. The elastic properties of soft biological tissues vary, many fold with malignancy. The experimental results show that laser speckle contrast (LSC) is very sensitive to the pathological changes in a soft tissue medium. The experiments are carried out on a phantom with two cylindrical inclusions of sizes 6mm in diameter, separated by 8mm between them. Three samples are made. One inclusion has Young's modulus E of 40kPa. The second inclusion has either a Young's modulus E of 20kPa, or scattering coefficient of μs'=3.00mm-1 or absorption coefficient of μa=0.03mm-1. The optical absorption (μa), reduced scattering (μs') coefficient, and the Young's modulus of the background are μa=0.01mm-1, μs'=1.00mm-1 and 12kPa, respectively. The experiments are carried out on all three phantoms. On a phantom with two inclusions of Young's modulus of 20 and 40kPa, the measured relative speckle image contrasts are 36.55% and 63.72%, respectively. Experiments are repeated on phantoms with inclusions of μa=0.03mm-1, E =40kPa and μs'=3.00mm-1. The results show that it is possible to detect inclusions with contrasts in optical absorption, optical scattering, and Young's modulus. Studies of the variation of laser speckle contrast with ultrasound driving force for various values of μa, μs', and Young's modulus of the tissue mimicking medium are also carried out.

  20. Video game players show higher performance but no difference in speed of attention shifts.

    PubMed

    Mack, David J; Wiesmann, Helene; Ilg, Uwe J

    2016-09-01

    Video games have become both a widespread leisure activity and a substantial field of research. In a variety of tasks, video game players (VGPs) perform better than non-video game players (NVGPs). This difference is most likely explained by an alteration of the basic mechanisms underlying visuospatial attention. More specifically, the present study hypothesizes that VGPs are able to shift attention faster than NVGPs. Such alterations in attention cannot be disentangled from changes in stimulus-response mappings in reaction time based measurements. Therefore, we used a spatial cueing task with varying cue lead times (CLTs) to investigate the speed of covert attention shifts of 98 male participants divided into 36 NVGPs and 62 VGPs based on their weekly gaming time. VGPs exhibited higher peak and mean performance than NVGPs. However, we did not find any differences in the speed of covert attention shifts as measured by the CLT needed to achieve peak performance. Thus, our results clearly rule out faster stimulus-response mappings as an explanation for the higher performance of VGPs in line with previous studies. More importantly, our data do not support the notion of faster attention shifts in VGPs as another possible explanation. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Quantitative phase imaging of human red blood cells using phase-shifting white light interference microscopy with colour fringe analysis

    NASA Astrophysics Data System (ADS)

    Singh Mehta, Dalip; Srivastava, Vishal

    2012-11-01

    We report quantitative phase imaging of human red blood cells (RBCs) using phase-shifting interference microscopy. Five phase-shifted white light interferograms are recorded using colour charge coupled device camera. White light interferograms were decomposed into red, green, and blue colour components. The phase-shifted interferograms of each colour were then processed by phase-shifting analysis and phase maps for red, green, and blue colours were reconstructed. Wavelength dependent refractive index profiles of RBCs were computed from the single set of white light interferogram. The present technique has great potential for non-invasive determination of refractive index variation and morphological features of cells and tissues.

  2. The Use of Outcome Mapping in the Educational Context

    ERIC Educational Resources Information Center

    Lewis, Anna

    2014-01-01

    Outcome Mapping is intended to measure the process by which change occurs, it shifts away from the products of the program to focus on changes in behaviors, relationships, actions, and/or activities of the people involved in the treatment program. This process-oriented methodology, most often used in designing and evaluating community development…

  3. Day Service Provision for People with Intellectual Disabilities: A Case Study Mapping 15-Year Trends in Ireland

    ERIC Educational Resources Information Center

    Fleming, Padraic; McGilloway, Sinead; Barry, Sarah

    2017-01-01

    Background: Day services for people with intellectual disabilities are experiencing a global paradigm shift towards innovative person-centred models of care. This study maps changing trends in day service utilization to highlight how policy, emergent patterns and demographic trends influence service delivery. Methods: National intellectual…

  4. Agent-Based Mapping of Credit Risk for Sustainable Microfinance

    PubMed Central

    Lee, Joung-Hun; Jusup, Marko; Podobnik, Boris; Iwasa, Yoh

    2015-01-01

    By drawing analogies with independent research areas, we propose an unorthodox framework for mapping microfinance credit risk---a major obstacle to the sustainability of lenders outreaching to the poor. Specifically, using the elements of network theory, we constructed an agent-based model that obeys the stylized rules of microfinance industry. We found that in a deteriorating economic environment confounded with adverse selection, a form of latent moral hazard may cause a regime shift from a high to a low loan payment probability. An after-the-fact recovery, when possible, required the economic environment to improve beyond that which led to the shift in the first place. These findings suggest a small set of measurable quantities for mapping microfinance credit risk and, consequently, for balancing the requirements to reasonably price loans and to operate on a fully self-financed basis. We illustrate how the proposed mapping works using a 10-year monthly data set from one of the best-known microfinance representatives, Grameen Bank in Bangladesh. Finally, we discuss an entirely new perspective for managing microfinance credit risk based on enticing spontaneous cooperation by building social capital. PMID:25945790

  5. Agent-based mapping of credit risk for sustainable microfinance.

    PubMed

    Lee, Joung-Hun; Jusup, Marko; Podobnik, Boris; Iwasa, Yoh

    2015-01-01

    By drawing analogies with independent research areas, we propose an unorthodox framework for mapping microfinance credit risk--a major obstacle to the sustainability of lenders outreaching to the poor. Specifically, using the elements of network theory, we constructed an agent-based model that obeys the stylized rules of microfinance industry. We found that in a deteriorating economic environment confounded with adverse selection, a form of latent moral hazard may cause a regime shift from a high to a low loan payment probability. An after-the-fact recovery, when possible, required the economic environment to improve beyond that which led to the shift in the first place. These findings suggest a small set of measurable quantities for mapping microfinance credit risk and, consequently, for balancing the requirements to reasonably price loans and to operate on a fully self-financed basis. We illustrate how the proposed mapping works using a 10-year monthly data set from one of the best-known microfinance representatives, Grameen Bank in Bangladesh. Finally, we discuss an entirely new perspective for managing microfinance credit risk based on enticing spontaneous cooperation by building social capital.

  6. Telling the story of tree species’ range shifts in a complex landscape

    Treesearch

    Sharon M. Stanton; Vicente J. Monleon; Heather E. Lintz; Joel Thompson

    2015-01-01

    The Forest Inventory and Analysis Program is the unrivaled source for long-term, spatially balanced, publicly available data. FIA will continue to be providers of data, but the program is growing and adapting, including a shift in how we communicate information and knowledge derived from those data. Online applications, interactive mapping, and infographics provide...

  7. Determining the Extent and Characterizing Coral Reef Habitats of the Northern Latitudes of the Florida Reef Tract (Martin County)

    PubMed Central

    Walker, Brian K.; Gilliam, David S.

    2013-01-01

    Climate change has recently been implicated in poleward shifts of many tropical species including corals; thus attention focused on higher-latitude coral communities is warranted to investigate possible range expansions and ecosystem shifts due to global warming. As the northern extension of the Florida Reef Tract (FRT), the third-largest barrier reef ecosystem in the world, southeast Florida (25–27° N latitude) is a prime region to study such effects. Most of the shallow-water FRT benthic habitats have been mapped, however minimal data and limited knowledge exist about the coral reef communities of its northernmost reaches off Martin County. First benthic habitat mapping was conducted using newly acquired high resolution LIDAR bathymetry and aerial photography where possible to map the spatial extent of coral reef habitats. Quantitative data were collected to characterize benthic cover and stony coral demographics and a comprehensive accuracy assessment was performed. The data were then analyzed in a habitat biogeography context to determine if a new coral reef ecosystem region designation was warranted. Of the 374 km2 seafloor mapped, 95.2% was Sand, 4.1% was Coral Reef and Colonized Pavement, and 0.7% was Other Delineations. Map accuracy assessment yielded an overall accuracy of 94.9% once adjusted for known map marginal proportions. Cluster analysis of cross-shelf habitat type and widths indicated that the benthic habitats were different than those further south and warranted designation of a new coral reef ecosystem region. Unlike the FRT further south, coral communities were dominated by cold-water tolerant species and LIDAR morphology indicated no evidence of historic reef growth during warmer climates. Present-day hydrographic conditions may be inhibiting poleward expansion of coral communities along Florida. This study provides new information on the benthic community composition of the northern FRT, serving as a baseline for future community shift and range expansion investigations. PMID:24282542

  8. Determining the extent and characterizing coral reef habitats of the northern latitudes of the Florida Reef Tract (Martin County).

    PubMed

    Walker, Brian K; Gilliam, David S

    2013-01-01

    Climate change has recently been implicated in poleward shifts of many tropical species including corals; thus attention focused on higher-latitude coral communities is warranted to investigate possible range expansions and ecosystem shifts due to global warming. As the northern extension of the Florida Reef Tract (FRT), the third-largest barrier reef ecosystem in the world, southeast Florida (25-27° N latitude) is a prime region to study such effects. Most of the shallow-water FRT benthic habitats have been mapped, however minimal data and limited knowledge exist about the coral reef communities of its northernmost reaches off Martin County. First benthic habitat mapping was conducted using newly acquired high resolution LIDAR bathymetry and aerial photography where possible to map the spatial extent of coral reef habitats. Quantitative data were collected to characterize benthic cover and stony coral demographics and a comprehensive accuracy assessment was performed. The data were then analyzed in a habitat biogeography context to determine if a new coral reef ecosystem region designation was warranted. Of the 374 km(2) seafloor mapped, 95.2% was Sand, 4.1% was Coral Reef and Colonized Pavement, and 0.7% was Other Delineations. Map accuracy assessment yielded an overall accuracy of 94.9% once adjusted for known map marginal proportions. Cluster analysis of cross-shelf habitat type and widths indicated that the benthic habitats were different than those further south and warranted designation of a new coral reef ecosystem region. Unlike the FRT further south, coral communities were dominated by cold-water tolerant species and LIDAR morphology indicated no evidence of historic reef growth during warmer climates. Present-day hydrographic conditions may be inhibiting poleward expansion of coral communities along Florida. This study provides new information on the benthic community composition of the northern FRT, serving as a baseline for future community shift and range expansion investigations.

  9. Dissociable meta-analytic brain networks contribute to coordinated emotional processing.

    PubMed

    Riedel, Michael C; Yanes, Julio A; Ray, Kimberly L; Eickhoff, Simon B; Fox, Peter T; Sutherland, Matthew T; Laird, Angela R

    2018-06-01

    Meta-analytic techniques for mining the neuroimaging literature continue to exert an impact on our conceptualization of functional brain networks contributing to human emotion and cognition. Traditional theories regarding the neurobiological substrates contributing to affective processing are shifting from regional- towards more network-based heuristic frameworks. To elucidate differential brain network involvement linked to distinct aspects of emotion processing, we applied an emergent meta-analytic clustering approach to the extensive body of affective neuroimaging results archived in the BrainMap database. Specifically, we performed hierarchical clustering on the modeled activation maps from 1,747 experiments in the affective processing domain, resulting in five meta-analytic groupings of experiments demonstrating whole-brain recruitment. Behavioral inference analyses conducted for each of these groupings suggested dissociable networks supporting: (1) visual perception within primary and associative visual cortices, (2) auditory perception within primary auditory cortices, (3) attention to emotionally salient information within insular, anterior cingulate, and subcortical regions, (4) appraisal and prediction of emotional events within medial prefrontal and posterior cingulate cortices, and (5) induction of emotional responses within amygdala and fusiform gyri. These meta-analytic outcomes are consistent with a contemporary psychological model of affective processing in which emotionally salient information from perceived stimuli are integrated with previous experiences to engender a subjective affective response. This study highlights the utility of using emergent meta-analytic methods to inform and extend psychological theories and suggests that emotions are manifest as the eventual consequence of interactions between large-scale brain networks. © 2018 Wiley Periodicals, Inc.

  10. Putting Climate Change on the Map: A Translation from Time to Space

    NASA Astrophysics Data System (ADS)

    Marzeion, B.; Bethke, I.; Drange, H.

    2009-04-01

    By increasing the concentrations of atmospheric greenhouses gases, man is changing the physical geography of planet Earth. This message is often given to the public in form of rather abstract numbers, such as changes in the annual mean surface temperature. Therefore, one of the difficulties to overcome when educating the public about climate change is to translate these abstract numbers into everyday experiences - a task that is not easy given the statistical and thereby abstract definition of the term 'climate' itself. However, climate does not only vary with time, but also with space, and people generally have a better idea of what it would be like to live in another place, than to experience an annual mean temperature rise of e.g. 3 K. We used the model calculations from the fourth assessment report of the Intergovernmental Panel on Climate Change to translate the projected temperature change into a change of location: Each point on a geographical map is shifted to the closest location that in the year 2000 has the annual mean temperature that the point is projected to have at some time in the future. With this method, it is possible to create a new kind of accessible and visually appealing illustration of climate change, answering the question: Where do I have to go today to experience tomorrow's climate? Similarly, it is possible to answer a related question: Where would I have to move if I want to continue living in today's climate?

  11. Brain electric microstates and momentary conscious mind states as building blocks of spontaneous thinking: I. Visual imagery and abstract thoughts.

    PubMed

    Lehmann, D; Strik, W K; Henggeler, B; Koenig, T; Koukkou, M

    1998-06-01

    Prompted reports of recall of spontaneous, conscious experiences were collected in a no-input, no-task, no-response paradigm (30 random prompts to each of 13 healthy volunteers). The mentation reports were classified into visual imagery and abstract thought. Spontaneous 19-channel brain electric activity (EEG) was continuously recorded, viewed as series of momentary spatial distributions (maps) of the brain electric field and segmented into microstates, i.e. into time segments characterized by quasi-stable landscapes of potential distribution maps which showed varying durations in the sub-second range. Microstate segmentation used a data-driven strategy. Different microstates, i.e. different brain electric landscapes must have been generated by activity of different neural assemblies and therefore are hypothesized to constitute different functions. The two types of reported experiences were associated with significantly different microstates (mean duration 121 ms) immediately preceding the prompts; these microstates showed, across subjects, for abstract thought (compared to visual imagery) a shift of the electric gravity center to the left and a clockwise rotation of the field axis. Contrariwise, the microstates 2 s before the prompt did not differ between the two types of experiences. The results support the hypothesis that different microstates of the brain as recognized in its electric field implement different conscious, reportable mind states, i.e. different classes (types) of thoughts (mentations); thus, the microstates might be candidates for the 'atoms of thought'.

  12. Grounded theory: a methodological spiral from positivism to postmodernism.

    PubMed

    Mills, Jane; Chapman, Ysanne; Bonner, Ann; Francis, Karen

    2007-04-01

    Our aim in this paper is to explain a methodological/methods package devised to incorporate situational and social world mapping with frame analysis, based on a grounded theory study of Australian rural nurses' experiences of mentoring. Situational analysis, as conceived by Adele Clarke, shifts the research methodology of grounded theory from being located within a postpositivist paradigm to a postmodern paradigm. Clarke uses three types of maps during this process: situational, social world and positional, in combination with discourse analysis. During our grounded theory study, the process of concurrent interview data generation and analysis incorporated situational and social world mapping techniques. An outcome of this was our increased awareness of how outside actors influenced participants in their constructions of mentoring. In our attempts to use Clarke's methodological package, however, it became apparent that our constructivist beliefs about human agency could not be reconciled with the postmodern project of discourse analysis. We then turned to the literature on symbolic interactionism and adopted frame analysis as a method to examine the literature on rural nursing and mentoring as secondary form of data. While we found situational and social world mapping very useful, we were less successful in using positional maps. In retrospect, we would argue that collective action framing provides an alternative to analysing such positions in the literature. This is particularly so for researchers who locate themselves within a constructivist paradigm, and who are therefore unwilling to reject the notion of human agency and the ability of individuals to shape their world in some way. Our example of using this package of situational and social worlds mapping with frame analysis is intended to assist other researchers to locate participants more transparently in the social worlds that they negotiate in their everyday practice.

  13. An analysis of clock-shift experiments: is scatter increased and deflection reduced in clock-shifted homing pigeons?

    PubMed

    Chappell

    1997-01-01

    Clock-shifting (altering the phase of the internal clock) in homing pigeons leads to a deflection in the vanishing bearing of the clock-shifted group relative to controls. However, two unexplained phenomena are common in clock-shift experiments: the vanishing bearings of the clock-shifted group are often more scattered (with a shorter vector length) than those of the control group, and the deflection of the mean bearing of the clock-shifted group from that of the controls is often smaller than expected theoretically. Here, an analysis of 55 clock-shift experiments performed in four countries over 21 years is reported. The bearings of the clock-shifted groups were significantly more scattered than those of controls and less deflected than expected, but these effects were not significantly different at familiar and unfamiliar sites. The possible causes of the effects are discussed and evaluated with reference to this analysis and other experiments. The most likely causes appear to be conflict between the directions indicated by the sun compass and either unshifted familiar visual landmarks (at familiar sites only) or the unshifted magnetic compass (possible at both familiar and unfamiliar sites).

  14. Changes in hydrogen isotope ratios in sequential plumage stages: an implication for the creation of isotope-base maps for tracking migratory birds.

    PubMed

    Duxbury, J M; Holroyd, G L; Muehlenbachs, K

    2003-09-01

    Accurate reference maps are important in the use of stable-isotopes to track the movements of migratory birds. Reference maps created by the analysis of samples collected from young at the nest site are more accurate than simply referring to naturally occurring patterns of hydrogen isotope ratios created by precipitation cycles. Ratios of hydrogen isotopes in the nutrients incorporated early in the development of young birds can be derived from endogenous, maternal sources. Base-maps should be created with the analysis of tissue samples from hatchlings after local the isotopic signature of exogenous nutrients is dominant. Migratory species such as Peregrine Falcons are known to use endogenous sources in the creation of their eggs, therefore knowledge of what plumage stage best represents the local hydrogen ratios would assist in the planning of nest visits. We conducted diet manipulation experiments involving Japanese Quail and Peregrine Falcons to determine the plumage stage when hydrogen isotope ratios were indicative of a switch in their food source. The natal down of both the quail and falcons reflected the diet of breeding adult females. The hydrogen isotope ratios of a new food source were dominant in the juvenile down of the young falcons, although a further shift was detected in the final juvenile plumage. The juvenile plumage is grown during weeks 3-4 after hatch on Peregrine Falcons. Nest visits for the purpose of collecting feathers for isotope-base-map creation should be made around 4 weeks after the presumed hatch of the young falcons.

  15. A new pooling strategy for high-throughput screening: the Shifted Transversal Design

    PubMed Central

    Thierry-Mieg, Nicolas

    2006-01-01

    Background In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and false negatives are a major concern. Pooling constitutes a natural solution: it reduces the number of tests, while providing critical duplication of the individual experiments, thereby correcting for experimental noise. The main difficulty consists in designing the pools in a manner that is both efficient and robust: few pools should be necessary to correct the errors and identify the positives, yet the experiment should not be too vulnerable to biological shakiness. For example, some information should still be obtained even if there are slightly more positives or errors than expected. This is known as the group testing problem, or pooling problem. Results In this paper, we present a new non-adaptive combinatorial pooling design: the "shifted transversal design" (STD). It relies on arithmetics, and rests on two intuitive ideas: minimizing the co-occurrence of objects, and constructing pools of constant-sized intersections. We prove that it allows unambiguous decoding of noisy experimental observations. This design is highly flexible, and can be tailored to function robustly in a wide range of experimental settings (i.e., numbers of objects, fractions of positives, and expected error-rates). Furthermore, we show that our design compares favorably, in terms of efficiency, to the previously described non-adaptive combinatorial pooling designs. Conclusion This method is currently being validated by field-testing in the context of yeast-two-hybrid interactome mapping, in collaboration with Marc Vidal's lab at the Dana Farber Cancer Institute. Many similar projects could benefit from using the Shifted Transversal Design. PMID:16423300

  16. Self-Organization of an Artificial Neural Network Subjected to Attention Shift Impairments and Familiarity Preference, Characteristics Studied in Autism

    ERIC Educational Resources Information Center

    Gustafsson, Lennart; Paplinski, Andrew

    2004-01-01

    Autism is a developmental disorder with possibly multiple pathophysiologies. It has been theorized that cortical feature maps in individuals with autism are inadequate for forming abstract codes and representations. Cortical feature maps make it possible to classify stimuli, such as phonemes of speech, disregarding incidental detail. Hierarchies…

  17. "Theory at the Crossroads": Mapping Moments of Mathematics Education Research onto Paradigms of Inquiry

    ERIC Educational Resources Information Center

    Stinson, David W.; Walshaw, Margaret

    2017-01-01

    In this essay, traveling through the past half-century, the authors illustrate how mathematics education research shifted, theoretical, beyond its psychological and mathematical roots. Mapping four historical moments of mathematics education research onto broader paradigms of inquiry, the authors make a case for the field to take up a theoretical…

  18. Shifting Environmental Ranges and Biome Potential According to the Whittaker Relationship

    NASA Astrophysics Data System (ADS)

    de Jong, R.; Garonna, I.; Schaepman, M. E.

    2015-12-01

    Robert H. Whittaker classified biome types mainly as a function of Mean Annual Temperature (MAT) and Mean Annual Precipitation (MAP), resulting in the well-known Whittaker plot1. This relationship is still being used to map biomes globally2. The same inputs (MAT and MAP), augmented with a radiation proxy, are used in the resource-balance perspective for modeling large-scale vegetation productivity as a function of abiotic factors3. These two approaches, used in a temporally dynamic manner, provided us indicators of shifts in growth-limiting factors4 and associated environmental ranges of vegetation, which, in turn, are key indicators for the study of global change and biodiversity5. We present a study in which we used the Whittaker relationship and CRU TS 3.22 climatic data to map regions that showed variable biome potential. These regions are likely to indicate ecotones - i.e. interactions zones between biomes - that have been subject to abiotic change and where a change in the vegetation system can be anticipated. At the same time, we used remotely sensed data (GIMMS v3g 1982-2012) to study gradients in vegetation dynamics in these zones. Preliminary results show strongest environmental shifts in northern ecotones, e.g. on the tundra - boreal boundary, and associated changes in climatic growth-limiting factors4. [1] Whittaker RH (1975) Communities and Ecosystems, Macmillan, 385p.[2] Ricklefs RE (2008) The Economy of Nature, W. H. Freeman, 620p.[3] Field CB, Randerson JT, Malmström CM (1995) Global net primary production: Combining ecology and remote sensing. Remote Sensing of Environment, 51, 74-88.[4] Schenkel D, Garonna I, De Jong R, Schaepman ME (this conference) Linking Land Surface Phenology and Growth Limiting Factor Shifts over the Past 30 Years.[5] University of Zurich Research Priority Program on Global Change and Biodiversity, http://www.gcb.uzh.ch

  19. Implementation of a Configurable Fault Tolerant Processor (CFTP)

    DTIC Science & Technology

    2003-03-01

    internal structure ARCHITECTURE rtl OF log_barrel IS signal sel1, sel2, sel3, sel4 : std_logic_vector ( 1 downto 0); signal buf0b, buf0c...sel3(1) <= l_or_r and shift(2); sel3(0) <= ar_or_log and shift(2); sel4 (1) <= l_or_r and shift(3); sel4 (0) <= ar_or_log and shift(3); buf0b...out_word => buf3a ); mux4: word_mux4 port map ( a => buf3a, b => buf3b, c => buf3c, d => buf3d, sel => sel4

  20. Triple Modular Redundancy (TMR) in a Configurable Fault-Tolerant Processor (CFTP) for Space Applications

    DTIC Science & Technology

    2003-12-01

    internal structure ARCHITECTURE rtl OF log_barrel IS signal sel1, sel2, sel3, sel4 : std_logic_vector ( 1 downto 0); signal buf0b, buf0c, buf0d...shift(2); sel3(0) <= ar_or_log and shift(2); sel4 (1) <= l_or_r and shift(3); sel4 (0) <= ar_or_log and shift(3); buf0b <= in_word(14 downto 0...mux4: word_mux4 port map ( a => buf3a, b => buf3b, c => buf3c, d => buf3d, sel => sel4 , out_word => out_word

  1. The thalamo-cortical auditory receptive fields: regulation by the states of vigilance, learning and the neuromodulatory systems.

    PubMed

    Edeline, Jean-Marc

    2003-12-01

    The goal of this review is twofold. First, it aims to describe the dynamic regulation that constantly shapes the receptive fields (RFs) and maps in the thalamo-cortical sensory systems of undrugged animals. Second, it aims to discuss several important issues that remain unresolved at the intersection between behavioral neurosciences and sensory physiology. A first section presents the RF modulations observed when an undrugged animal spontaneously shifts from waking to slow-wave sleep or to paradoxical sleep (also called REM sleep). A second section shows that, in contrast with the general changes described in the first section, behavioral training can induce selective effects which favor the stimulus that has acquired significance during learning. A third section reviews the effects triggered by two major neuromodulators of the thalamo-cortical system--acetylcholine and noradrenaline--which are traditionally involved both in the switch of vigilance states and in learning experiences. The conclusion argues that because the receptive fields and maps of an awake animal are continuously modulated from minute to minute, learning-induced sensory plasticity can be viewed as a "crystallization" of the receptive fields and maps in one of the multiple possible states. Studying the interplays between neuromodulators can help understanding the neurobiological foundations of this dynamic regulation.

  2. An internal reference model-based PRF temperature mapping method with Cramer-Rao lower bound noise performance analysis.

    PubMed

    Li, Cheng; Pan, Xinyi; Ying, Kui; Zhang, Qiang; An, Jing; Weng, Dehe; Qin, Wen; Li, Kuncheng

    2009-11-01

    The conventional phase difference method for MR thermometry suffers from disturbances caused by the presence of lipid protons, motion-induced error, and field drift. A signal model is presented with multi-echo gradient echo (GRE) sequence using a fat signal as an internal reference to overcome these problems. The internal reference signal model is fit to the water and fat signals by the extended Prony algorithm and the Levenberg-Marquardt algorithm to estimate the chemical shifts between water and fat which contain temperature information. A noise analysis of the signal model was conducted using the Cramer-Rao lower bound to evaluate the noise performance of various algorithms, the effects of imaging parameters, and the influence of the water:fat signal ratio in a sample on the temperature estimate. Comparison of the calculated temperature map and thermocouple temperature measurements shows that the maximum temperature estimation error is 0.614 degrees C, with a standard deviation of 0.06 degrees C, confirming the feasibility of this model-based temperature mapping method. The influence of sample water:fat signal ratio on the accuracy of the temperature estimate is evaluated in a water-fat mixed phantom experiment with an optimal ratio of approximately 0.66:1. (c) 2009 Wiley-Liss, Inc.

  3. Teachers' Cultural Maps: Asia as a "Tricky Sort of Subject Matter" in Curriculum Inquiry

    ERIC Educational Resources Information Center

    Salter, Peta

    2014-01-01

    The refocussing of Australia-Asia relations is manifest in a combination of national policy moves in Australia. Parallel shifts have been made in Europe, the United States, Canada and New Zealand. In Australia, the curricular response to this shift has become known as "Asia literacy." This study is drawn from a wider project that…

  4. Continuous blood densitometry - Fluid shifts after graded hemorrhage in animals

    NASA Technical Reports Server (NTRS)

    Hinghofer-Szalkay, H.

    1986-01-01

    Rapid fluid shifts in four pigs and two dogs subjected to graded hemorrhage are investigated. Arterial blood density (BD), mean arterial pressure (MAP), central venous pressure (CVP), arterial plasma density (PD), hematocrit (Hct) and erythrocyte density were measured. The apparatus and mechancial oscillator technique for measuring density are described. Fluid shifts between red blood cells and blood plasma and alterations in the whole-body-to-large vessel Hct, F(cell) are studied using two models. The bases of the model calculations are discussed. A decrease in MAP, CVP, and BP is detected at the beginning of hemorrhaging; continued bleeding results in further BD decrease correlating with volume displacement. The data reveal that at 15 ml/kg blood loss the mean PD and BD dropped by 0.99 + or - 0.15 and 2.42 + or 0.26 g/liter, respectively, and the Hct dropped by 2.40 + or 0.47 units. The data reveal that inward-shifted fluid has a higher density than normal ultrafiltrate and/or there is a rise in the F(cell) ratio. It is noted that rapid fluid replacement ranged from 5.8 + or - 0.8 to 10.6 + or - 2.0 percent of the initial plasma volume.

  5. Crystal and source characterization for the Crystal Backlighter Imager capability at the National Ignition Facility

    NASA Astrophysics Data System (ADS)

    Krauland, C. M.; Hall, G. N.; Buscho, J. G.; Hibbard, R.; McCarville, T. J.; Lowe-Webb, R.; Ayers, S. L.; Kalantar, D.; Kohut, T.; Kemp, G. E.; Bradley, D. K.; Bell, P.; Landen, O. L.; Brewster, T. N.; Piston, K.

    2017-10-01

    The Crystal Backlighter Imager (CBI) is a very narrow bandwidth ( 10 eV) x-ray radiography system that uses Bragg reflection from a spherically-curved crystal at near normal incidence. This diagnostic has the capability to image late in an ICF implosion because it only requires the brightness of the backlighter to be larger than the capsule self-emission in that narrow bandwidth. While the limited bandwidth is advantageous for this reason, it also requires that the effective energy of the backlighter atomic line is known to 1 eV accuracy for proper crystal alignment. Any Doppler shift in the line energy must be understood for the imaging system to work. The work presented details characterization experiments done at the Jupiter Laser Facility with a Si (8 6 2) crystal that will be used with a Selenium backlighter in the NIF CBI diagnostic. We used the spherically-bent crystals to image a small ( 200 µm) He α source generated by the Janus laser on a Se foil. Scanning Bragg angles over multiple shots allowed us to map out the spectral line intensity distribution for optimal alignment in NIF. A subsequent Doppler shift measurement using CBI on NIF will also be presented with complementary HYDRA modeling for both experiments. Prepared by LLNL under Contract DE-AC52-07NA27344 and by General Atomics under Contract DE-NA0001808.

  6. Using satellite data in map design and production

    USGS Publications Warehouse

    Hutchinson, John A.

    2002-01-01

    Satellite image maps have been produced by the U.S. Geological Survey (USGS) since shortly after the launch of the first Landsat satellite in 1972. Over the years, the use of image data to design and produce maps has developed from a manual and photographic process to one that incorporates geographic information systems, desktop publishing, and digital prepress techniques. At the same time, the content of most image-based maps produced by the USGS has shifted from raw image data to land cover or other information layers derived from satellite imagery, often portrayed in combination with shaded relief.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soerensen, M.P.; Davidson, A.; Pedersen, N.F.

    We use the method of cell-to-cell mapping to locate attractors, basins, and saddle nodes in the phase plane of a driven Josephson junction. The cell-mapping method is discussed in some detail, emphasizing its ability to provide a global view of the phase plane. Our computations confirm the existence of a previously reported interior crisis. In addition, we observe a boundary crisis for a small shift in one parameter. The cell-mapping method allows us to show both crises explicitly in the phase plane, at low computational cost.

  8. Simultaneous Luminescence Pressure and Temperature Mapping

    NASA Technical Reports Server (NTRS)

    Buck, Gregory M. (Inventor)

    1998-01-01

    A simultaneous luminescence pressure and temperature mapping system is developed including improved dye application techniques for surface temperature and pressure measurements from 5 torr to 1000 torr with possible upgrade to from 0.5 torr to several atmospheres with improved camera resolution. Adsorbed perylene dye on slip-cast silica is pressure (oxygen) sensitive and reusable to relatively high temperatures (-150 C). Adsorbed luminescence has an approximately linear color shift with temperature, which can be used for independent temperature mapping and brightness pressure calibration with temperature.

  9. Simultaneous Luminescence Pressure and Temperature Mapping System

    NASA Technical Reports Server (NTRS)

    Buck, Gregory M. (Inventor)

    1995-01-01

    A simultaneous luminescence pressure and temperature mapping system is developed including improved dye application techniques for surface temperature and pressure measurements from 5 torr to 1000 torr with possible upgrade to from 0.5 torr to several atmospheres with improved camera resolution. Adsorbed perylene dye on slip-cast silica is pressure (oxygen) sensitive and reusable to relatively high temperatures (approximately 150 C). Adsorbed luminescence has an approximately linear color shift with temperature, which can be used for independent temperature mapping and brightness pressure calibration with temperature.

  10. Hydropodelogy From the Pedon to the Landscape: Challenges and Accomplishments in the National Cooperative Soil Survey

    NASA Astrophysics Data System (ADS)

    Hammer, D.; Richardson, J.; Hempel, J.; Market, P.

    2005-12-01

    American pedology has focused on the National Cooperative Soil Survey. Primary responsibility rests with the U.S. Department of Agriculture. The primary goals, are legislatively mandated, are to map the country's soils, make interpretations, provide information to clients, maintain and market the soil survey. The first goal is near completion and focus is shifting to the other three. Concomitantly, American pedological science is being impacted by several conditions: technological advances; land use changes at unprecedented scales and magnitudes; a burgeoning population increasingly "separated" from the land; and a major emphasis in universities upon biological ("life") sciences at the DNA scale - as if soil, nutrients and water are not life essentials. Effects of the Flood of 1993 and Hurricane Katrina suggest that humans do not understand earth/climate interactions, particularly climatic extremes. Pedologists know the focus on soil classification and mapping was at the expense of understanding processes. Hydropedology is a holistic approach to understanding soil and geomorphic process in order to predict the impacts of perturbations. Water movement on and in the soil is the primary mechanism of distributing and altering sediments and chemicals (pedogenesis), and depends for its success upon understanding that the soil profile is the record of developmental history at that landscape site. Hydropedologists believe soil scientists can use pedons (point data) from appropriate locations from flownets in complex landscapes to extrapolate processes. This is the "pedotransfer function" concept. Technological advances are coupled with the existing soil survey information to create important soil-landscape interpretations at a variety of scales. Early results have been very successful. Quantification of soil systems can be classified broadly into three categories; hard data, soft data and tacit knowledge. "Hard data" are measured numbers, and include such attributes as pH, texture, cation exchange capacity and event-specific rainfall. "Soft data" include soil maps, SSURGO data and climate maps. Soft data are combinations of observations, measurements and inferences that produce maps and models at various scales. "Tacit knowledge" is human understanding that results from focused experience within a system. A skilled soil scientist with tacit knowledge specific to a particular region can combination hard and soft data to develop important and useful interpretations and predictions. Illustrations from natural and urban settings will be provided. Soils and climate are temporally and spatially variable at all scales. Soil systems respond differently to different climates and perturbations. For example, the recent pluvial period in the Prairie Pothole region is changing surface soil sodium concentrations and locations and sizes of discharge wetlands. This is a relatively short-term response to a regional climate shift. Climatic shift in Oxisol landscapes will have little effect on soil cations. To optimize soil interpretations, focus must be on quantifying region-specific "dynamic" soil, geomorphic and climatic attributes. Recognizing these needs, the National Cooperative Soil Survey will develop regional watershed projects that focus on quantifying soil-water relationships that can be used at a variety of scales.

  11. Coherent optical transients observed in rubidium atomic line filtered Doppler velocimetry experiments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fajardo, Mario E., E-mail: mario.fajardo@eglin.af.mil; Molek, Christopher D.; Vesely, Annamaria L.

    2015-10-14

    We report the first successful results from our novel Rubidium Atomic Line Filtered (RALF) Doppler velocimetry apparatus, along with unanticipated oscillatory signals due to coherent optical transients generated within pure Rb vapor cells. RALF is a high-velocity and high-acceleration extension of the well-known Doppler Global Velocimetry (DGV) technique for constructing multi-dimensional flow velocity vector maps in aerodynamics experiments [H. Komine, U.S. Patent No. 4,919,536 (24 April 1990)]. RALF exploits the frequency dependence of pressure-broadened Rb atom optical absorptions in a heated Rb/N{sub 2} gas cell to encode the Doppler shift of reflected near-resonant (λ{sub 0} ≈ 780.24 nm) laser light onto the intensitymore » transmitted by the cell. The present RALF apparatus combines fiber optic and free-space components and was built to determine suitable operating conditions and performance parameters for the Rb/N{sub 2} gas cells. It yields single-spot velocities of thin laser-driven-flyer test surfaces and incorporates a simultaneous Photonic Doppler Velocimetry (PDV) channel [Strand et al., Rev. Sci. Instrum. 77, 083108 (2006)] for validation of the RALF results, which we demonstrate here over the v = 0 to 1 km/s range. Both RALF and DGV presume the vapor cells to be simple Beer's Law optical absorbers, so we were quite surprised to observe oscillatory signals in experiments employing low pressure pure Rb vapor cells. We interpret these oscillations as interference between the Doppler shifted reflected light and the Free Induction Decay (FID) coherent optical transient produced within the pure Rb cells at the original laser frequency; this is confirmed by direct comparison of the PDV and FID signals. We attribute the different behaviors of the Rb/N{sub 2} vs. Rb gas cells to efficient dephasing of the atomic/optical coherences by Rb-N{sub 2} collisions. The minimum necessary N{sub 2} buffer gas density ≈0.3 amagat translates into a smallest useful velocity range of 0 to 2 km/s, which can readily be extended to cover the 0 to 10 km/s range, and beyond. The recognition that coherent optical transients can be produced within low pressure vapor cells during velocimetry experiments may offer new insights into some quantitative discrepancies reported in earlier DGV studies. Future plans include “line-RALF” experiments with streak camera detection, and two-dimensional surface velocity mapping using pulsed laser illumination and/or gated intensified CCD camera detection.« less

  12. Surface plasmon holographic microscopy for near-field refractive index detection and thin film mapping

    NASA Astrophysics Data System (ADS)

    Zhao, Jianlin; Zhang, Jiwei; Dai, Siqing; Di, Jianglei; Xi, Teli

    2018-02-01

    Surface plasmon microscopy (SPM) is widely applied for label-free detection of changes of refractive index and concentration, as well as mapping thin films in near field. Traditionally, the SPM systems are based on the detection of light intensity or phase changes. Here, we present two kinds of surface plasmon holographic microscopy (SPHM) systems for amplitude- and phase-contrast imaging simultaneously. Through recording off-axis holograms and numerical reconstruction, the complex amplitude distributions of surface plasmon resonance (SPR) images can be obtained. According to the Fresnel's formula, in a prism/ gold/ dielectric structure, the reflection phase shift is uniquely decided by refractive index of the dielectric. By measuring the phase shift difference of the reflected light exploiting prism-coupling SPHM system based on common-path interference configuration, monitoring tiny refractive index variation and imaging biological tissue are performed. Furthermore, to characterize the thin film thickness in near field, we employ a four-layer SPR model in which the third film layer is within the evanescent field. The complex reflection coefficient, including the reflectivity and reflection phase shift, is uniquely decided by the film thickness. By measuring the complex amplitude distributions of the SPR images exploiting objective-coupling SPHM system based on common-path interference configuration, the thickness distributions of thin films are mapped with sub-nanometer resolution theoretically. Owing to its high temporal stability, the recommended SPHMs show great potentials for monitoring tiny refractive index variations, imaging biological tissues and mapping thin films in near field with dynamic, nondestructive and full-field measurement capabilities in chemistry, biomedicine field, etc.

  13. Influence of levels of information as presented by different technologies on students' understanding of acid, base, and ph concepts

    NASA Astrophysics Data System (ADS)

    Nakhleh, Mary B.; Krajcik, Joseph S.

    We investigated how different levels of information presented by various technologies affected secondary students' understanding of acid, base, and pH concepts. Secondary students who were selected for the study had just completed their study of acid-base chemistry. No attempt was made to provide further instruction. We analyzed changes in the understanding of individual students by constructing concept maps from the propositions that the students used in interviews conducted before and after a series of acid-base titrations. After the initial interview, students were divided into three groups. Within each group, students individually performed the same set of titrations using different technologies: chemical indicators, pH meters, and microcomputer-based laboratories (MBL). After the titrations were completed, all students were interviewed again. We found that students using MBL exhibited a larger positive shift in their concept map scores, which indicates a greater differentiation and integration of their knowledge of acids and bases. The chemical indicator students exhibited a more moderate positive shift in their concept map scores, and the pH meter students exhibited a smaller positive shift. We also found that the MBL students constructed more inappropriate links in their concept maps than the chemical indicator or pH meter students. However, we speculate that this increased number of inappropriate links indicates a high level of involvement with the technology. We therefore argue that the level of information offered by the technology affected students' understanding of the chemical concepts.Received: 24 February 1993; Revised: 21 February 1994;

  14. Doppler color imaging. Principles and instrumentation.

    PubMed

    Kremkau, F W

    1992-01-01

    DCI acquires Doppler-shifted echoes from a cross-section of tissue scanned by an ultrasound beam. These echoes are then presented in color and superimposed on the gray-scale anatomic image of non-Doppler-shifted echoes received during the scan. The flow echoes are assigned colors according to the color map chosen. Usually red, yellow, or white indicates positive Doppler shifts (approaching flow) and blue, cyan, or white indicates negative shifts (receding flow). Green is added to indicate variance (disturbed or turbulent flow). Several pulses (the number is called the ensemble length) are needed to generate a color scan line. Linear, convex, phased, and annular arrays are used to acquire the gray-scale and color-flow information. Doppler color-flow instruments are pulsed-Doppler instruments and are subject to the same limitations, such as Doppler angle dependence and aliasing, as other Doppler instruments. Color controls include gain, TGC, map selection, variance on/off, persistence, ensemble length, color/gray priority. Nyquist limit (PRF), baseline shift, wall filter, and color window angle, location, and size. Doppler color-flow instruments generally have output intensities intermediate between those of gray-scale imaging and pulsed-Doppler duplex instruments. Although there is no known risk with the use of color-flow instruments, prudent practice dictates that they be used for medical indications and with the minimum exposure time and instrument output required to obtain the needed diagnostic information.

  15. Improved diagonal queue medical image steganography using Chaos theory, LFSR, and Rabin cryptosystem.

    PubMed

    Jain, Mamta; Kumar, Anil; Choudhary, Rishabh Charan

    2017-06-01

    In this article, we have proposed an improved diagonal queue medical image steganography for patient secret medical data transmission using chaotic standard map, linear feedback shift register, and Rabin cryptosystem, for improvement of previous technique (Jain and Lenka in Springer Brain Inform 3:39-51, 2016). The proposed algorithm comprises four stages, generation of pseudo-random sequences (pseudo-random sequences are generated by linear feedback shift register and standard chaotic map), permutation and XORing using pseudo-random sequences, encryption using Rabin cryptosystem, and steganography using the improved diagonal queues. Security analysis has been carried out. Performance analysis is observed using MSE, PSNR, maximum embedding capacity, as well as by histogram analysis between various Brain disease stego and cover images.

  16. Investigating the Impact of NGSS-Aligned Professional Development on PreK-3 Teachers' Science Content Knowledge and Pedagogy

    NASA Astrophysics Data System (ADS)

    Tuttle, Nicole; Kaderavek, Joan N.; Molitor, Scott; Czerniak, Charlene M.; Johnson-Whitt, Eugenia; Bloomquist, Debra; Namatovu, Winnifred; Wilson, Grant

    2016-11-01

    This pilot study investigates the impact of a 2-week professional development Summer Institute on PK-3 teachers' knowledge and practices. This Summer Institute is a component of [program], a large-scale early-childhood science project that aims to transform PK-3 science teaching. The mixed-methods study examined concept maps, lesson plans, and classroom observations to measure possible changes in PK-3 teachers' science content knowledge and classroom practice from 11 teachers who attended the 2014 Summer Institute. Analysis of the concept maps demonstrated statistically significant growth in teachers' science content knowledge. Analysis of teachers' lesson plans demonstrated that the teachers could design high quality science inquiry lessons aligned to the Next Generation Science Standards following the professional development. Finally, examination of teachers' pre- and post-Summer Institute videotaped inquiry lessons showed evidence that teachers were incorporating new inquiry practices into their teaching, especially regarding classroom discourse. Our results suggest that an immersive inquiry experience is effective at beginning a shift towards reform-aligned science and engineering instruction but that early elementary educators require additional support for full mastery.

  17. Auditory-motor Mapping for Pitch Control in Singers and Nonsingers

    PubMed Central

    Jones, Jeffery A.; Keough, Dwayne

    2009-01-01

    Little is known about the basic processes underlying the behavior of singing. This experiment was designed to examine differences in the representation of the mapping between fundamental frequency (F0) feedback and the vocal production system in singers and nonsingers. Auditory feedback regarding F0 was shifted down in frequency while participants sang the consonant-vowel /ta/. During the initial frequency-altered trials, singers compensated to a lesser degree than nonsingers, but this difference was reduced with continued exposure to frequency-altered feedback. After brief exposure to frequency altered auditory feedback, both singers and nonsingers suddenly heard their F0 unaltered. When participants received this unaltered feedback, only singers' F0 values were found to be significantly higher than their F0 values produced during baseline and control trials. These aftereffects in singers were replicated when participants sang a different note than the note they produced while hearing altered feedback. Together, these results suggest that singers rely more on internal models than nonsingers to regulate vocal productions rather than real time auditory feedback. PMID:18592224

  18. Neuronal Polarity: MAP2 Shifts Secretory Vesicles into High Gear for Long-Haul Transport down the Axon.

    PubMed

    Ribeiro, Luís F; de Wit, Joris

    2017-04-19

    Accurate control of polarized cargo trafficking is essential for neuronal function. In this issue of Neuron, Gumy et al. (2017) show that MAP2 defines a pre-axonal filtering zone and controls axonal cargo transport by influencing the activities of distinct kinesin motors. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Determination of Residual Stress Distributions in Polycrystalline Alumina using Fluorescence Microscopy

    PubMed Central

    Michaels, Chris A.; Cook, Robert F.

    2016-01-01

    Maps of residual stress distributions arising from anisotropic thermal expansion effects in a polycrystalline alumina are generated using fluorescence microscopy. The shifts of both the R1 and R2 ruby fluorescence lines of Cr in alumina are used to create maps with sub-µm resolution of either the local mean and shear stresses or local crystallographic a- and c-stresses in the material, with approximately ± 1 MPa stress resolution. The use of single crystal control materials and explicit correction for temperature and composition effects on line shifts enabled determination of the absolute values and distributions of values of stresses. Temperature correction is shown to be critical in absolute stress determination. Experimental determinations of average stress parameters in the mapped structure are consistent with assumed equilibrium conditions and with integrated large-area measurements. Average crystallographic stresses of order hundreds of MPa are determined with characteristic distribution widths of tens of MPa. The stress distributions reflect contributions from individual clusters of stress in the structure; the cluster size is somewhat larger than the grain size. An example application of the use of stress maps is shown in the calculation of stress-intensity factors for fracture in the residual stress field. PMID:27563163

  20. On the dualization of scalars into ( d - 2)-forms in supergravity. Momentum maps, R-symmetry and gauged supergravity

    NASA Astrophysics Data System (ADS)

    Bandos, Igor A.; Ortín, Tomás

    2016-08-01

    We review and investigate different aspects of scalar fields in supergravity theories both when they parametrize symmetric spaces and when they parametrize spaces of special holonomy which are not necessarily symmetric (Kähler and Quaternionic-Kähler spaces): their rôle in the definition of derivatives of the fermions covariant under the R-symmetry group and (in gauged supergravities) under some gauge group, their dualization into ( d - 2)-forms, their role in the supersymmetry transformation rules (via fermion shifts, for instance) etc. We find a general definition of momentum map that applies to any manifold admitting a Killing vector and coincides with those of the holomorphic and tri-holomorphic momentum maps in Kähler and quaternionic-Kähler spaces and with an independent definition that can be given in symmetric spaces. We show how the momen-tum map occurs ubiquitously: in gauge-covariant derivatives of fermions, in fermion shifts, in the supersymmetry transformation rules of ( d - 2)-forms etc. We also give the general structure of the Noether-Gaillard-Zumino conserved currents in theories with fields of different ranks in any dimension.

  1. Simultaneous mapping of water shift and B1 (WASABI)-Application to field-Inhomogeneity correction of CEST MRI data.

    PubMed

    Schuenke, Patrick; Windschuh, Johannes; Roeloffs, Volkert; Ladd, Mark E; Bachert, Peter; Zaiss, Moritz

    2017-02-01

    Together with the development of MRI contrasts that are inherently small in their magnitude, increased magnetic field accuracy is also required. Hence, mapping of the static magnetic field (B 0 ) and the excitation field (B 1 ) is not only important to feedback shim algorithms, but also for postprocess contrast-correction procedures. A novel field-inhomogeneity mapping method is presented that allows simultaneous mapping of the water shift and B 1 (WASABI) using an off-resonant rectangular preparation pulse. The induced Rabi oscillations lead to a sinc-like spectrum in the frequency-offset dimension and allow for determination of B 0 by its symmetry axis and of B 1 by its oscillation frequency. Stability of the WASABI method with regard to the influences of T 1 , T 2 , magnetization transfer, and repetition time was investigated and its convergence interval was verified. B 0 and B 1 maps obtained simultaneously by means of WASABI in the human brain at 3 T and 7 T can compete well with maps obtained by standard methods. Finally, the method was applied successfully for B 0 and B 1 correction of chemical exchange saturation transfer MRI (CEST-MRI) data of the human brain. The proposed WASABI method yields a novel simultaneous B 0 and B 1 mapping within 1 min that is robust and easy to implement. Magn Reson Med 77:571-580, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  2. Narrative event boundaries, reading times, and expectation.

    PubMed

    Pettijohn, Kyle A; Radvansky, Gabriel A

    2016-10-01

    During text comprehension, readers create mental representations of the described events, called situation models. When new information is encountered, these models must be updated or new ones created. Consistent with the event indexing model, previous studies have shown that when readers encounter an event shift, reading times often increase. However, such increases are not consistently observed. This paper addresses this inconsistency by examining the extent to which reading-time differences observed at event shifts reflect an unexpectedness in the narrative rather than processes involved in model updating. In two reassessments of prior work, event shifts known to increase reading time were rated as less expected, and expectedness ratings significantly predicted reading time. In three new experiments, participants read stories in which an event shift was or was not foreshadowed, thereby influencing expectedness of the shift. Experiment 1 revealed that readers do not expect event shifts, but foreshadowing eliminates this. Experiment 2 showed that foreshadowing does not affect identification of event shifts. Finally, Experiment 3 found that, although reading times increased when an event shift was not foreshadowed, they were not different from controls when it was. Moreover, responses to memory probes were slower following an event shift regardless of foreshadowing, suggesting that situation model updating had taken place. Overall, the results support the idea that previously observed reading time increases at event shifts reflect, at least in part, a reader's unexpected encounter with a shift rather than an increase in processing effort required to update a situation model.

  3. CRF-PEPICO: Double velocity map imaging photoelectron photoion coincidence spectroscopy for reaction kinetics studies

    NASA Astrophysics Data System (ADS)

    Sztáray, Bálint; Voronova, Krisztina; Torma, Krisztián G.; Covert, Kyle J.; Bodi, Andras; Hemberger, Patrick; Gerber, Thomas; Osborn, David L.

    2017-07-01

    Photoelectron photoion coincidence (PEPICO) spectroscopy could become a powerful tool for the time-resolved study of multi-channel gas phase chemical reactions. Toward this goal, we have designed and tested electron and ion optics that form the core of a new PEPICO spectrometer, utilizing simultaneous velocity map imaging for both cations and electrons, while also achieving good cation mass resolution through space focusing. These optics are combined with a side-sampled, slow-flow chemical reactor for photolytic initiation of gas-phase chemical reactions. Together with a recent advance that dramatically increases the dynamic range in PEPICO spectroscopy [D. L. Osborn et al., J. Chem. Phys. 145, 164202 (2016)], the design described here demonstrates a complete prototype spectrometer and reactor interface to carry out time-resolved experiments. Combining dual velocity map imaging with cation space focusing yields tightly focused photoion images for translationally cold neutrals, while offering good mass resolution for thermal samples as well. The flexible optics design incorporates linear electric fields in the ionization region, surrounded by dual curved electric fields for velocity map imaging of ions and electrons. Furthermore, the design allows for a long extraction stage, which makes this the first PEPICO experiment to combine ion imaging with the unimolecular dissociation rate constant measurements of cations to detect and account for kinetic shifts. Four examples are shown to illustrate some capabilities of this new design. We recorded the threshold photoelectron spectrum of the propargyl and the iodomethyl radicals. While the former agrees well with a literature threshold photoelectron spectrum, we have succeeded in resolving the previously unobserved vibrational structure in the latter. We have also measured the bimolecular rate constant of the CH2I + O2 reaction and observed its product, the smallest Criegee intermediate, CH2OO. Finally, the second dissociative photoionization step of iodocyclohexane ions, the loss of ethylene from the cyclohexyl cation, is slow at threshold, as illustrated by the asymmetric threshold photoionization time-of-flight distributions.

  4. Results from the Modern Eddington Experiment

    NASA Astrophysics Data System (ADS)

    Schaefer, Bradley E.; Hynes, Robert I.

    2018-01-01

    The original Eddington Eclipse Experiment (for the 29 May 1919 total solar eclipse) was a test of Einstein's General Relativity, which predicted that the apparent positions of stars near the eclipsed Sun would be shifted outward by up to 1.7". Their results were from 7 stars on 7 plates, with the measured shift at the solar limb of 1.98±0.12". On 6 November 1919, Eddington announced the triumph of Einstein, with many far-reaching effects. To further test General Relativity, the basic 'Eddington eclipse experiment' was run successfully at six later eclipses (the last in 1973), all with only ~10% accuracy.Over the last few years it has become possible to move past the old technology of photographic plates, due to the production of large-scale monochromatic CCD chips. A large number of pixels across is required so that a large field-of-view can go along with adequate resolution. These chips are now commercially available. The perfect opportunity arose with the 21 August 2017 total solar eclipse. Suddenly, it was possible for ordinary astronomers to test Einstein with simple off-the-shelf equipment.We ran a Modern Eddington Experiment from Casper Wyoming. We used the SBIG STX 16803 CCD camera (4096X4096, 9 micron pixels), along with a TeleVue NP101is APO refractor (4.0" aperture, F=540 mm). After experiments, it was decided to run without any filter. The plate scale was near 382 "/mm, the pixel size was 3.4", and the field-of-view was 3.9°X3.9°. We obtained 39 1-second images of star fields centered (with substantial shifts between images) in the dark sky 7 hours before the eclipse, for the purpose of mapping out optical distortions and CCD imperfections. The system was untouched even until the eclipse was over. During the 146-second totality, with slight cirrus clouds, we obtained 11 eclipse images, with 1.0 and 0.5 second exposures, showing over 60 stars (to SNR=10) from 53"-155" from the Sun-center.The analysis is currently underway. Effects to be corrected for include differential refraction, differential aberration, proper motion, parallax, optical distortions, and the tangent plane. Final results should be completed by the time of our AAS meeting.

  5. Sensory adaptation for timing perception.

    PubMed

    Roseboom, Warrick; Linares, Daniel; Nishida, Shin'ya

    2015-04-22

    Recent sensory experience modifies subjective timing perception. For example, when visual events repeatedly lead auditory events, such as when the sound and video tracks of a movie are out of sync, subsequent vision-leads-audio presentations are reported as more simultaneous. This phenomenon could provide insights into the fundamental problem of how timing is represented in the brain, but the underlying mechanisms are poorly understood. Here, we show that the effect of recent experience on timing perception is not just subjective; recent sensory experience also modifies relative timing discrimination. This result indicates that recent sensory history alters the encoding of relative timing in sensory areas, excluding explanations of the subjective phenomenon based only on decision-level changes. The pattern of changes in timing discrimination suggests the existence of two sensory components, similar to those previously reported for visual spatial attributes: a lateral shift in the nonlinear transducer that maps relative timing into perceptual relative timing and an increase in transducer slope around the exposed timing. The existence of these components would suggest that previous explanations of how recent experience may change the sensory encoding of timing, such as changes in sensory latencies or simple implementations of neural population codes, cannot account for the effect of sensory adaptation on timing perception.

  6. Analysis of change in marsh types of coastal Louisiana, 1978-2001

    USGS Publications Warehouse

    Linscombe, Robert G.; Hartley, Stephen B.

    2011-01-01

    Scientists and geographers have provided multiple datasets and maps to document temporal changes in vegetation types and land-water relationships in coastal Louisiana. Although these maps provide useful historical information, technological limitations prevented these and other mapping efforts from providing sufficiently detailed calculations of areal changes and shifts in habitat coverage. The current analysis of habitat change draws upon these past mapping efforts but is based on an advanced, geographic information system dataset that was created by using Landsat 5 Thematic Mapper imagery and digital orthophoto quarter quadrangles. The objective of building this dataset was to more specifically define land-water relationships over time in coastal Louisiana, and it provides the most detailed analysis of vegetation shifts to date. In the current study, we have attempted to explain these vegetation shifts by interpreting them in the context of rainfall records, data from the Palmer Drought Severity Index, and salinity data. During the 23 years we analyzed, total marsh acreage decreased, with conversion of marsh to open water. Furthermore, the general trend across coastal Louisiana was a shift to increasingly fresh marsh types. Although fresh marsh remained almost the same during the 1978-88 study period, there were greater increases during the 1988-2001 study periods. Intermediate marsh followed the same pattern, whereas brackish marsh showed a reverse (decreasing) pattern. Changes in saline (saltwater) marsh were minimal. Interpreting shifts in marsh vegetation types by using climate and salinity data provides better understanding of factors influencing these changes and, therefore, can improve our ability to make predictions about future marsh loss related to vegetation changes. Results of our study indicate that precipitation fluctuations prior to vegetation surveys impacted salinities differently across the coast. For example, a wet 6 months prior to the survey may or may not have made up for a dry period during the earlier 12 months. More research is needed to better understand rainfall periods and how they affect salinity changes. The ability to understand past dynamics and to anticipate future trends in vegetation change and related land loss in the coastal region of Louisiana is a vital part of ongoing and future efforts to conserve its critical wetland ecosystem. With the loss of marsh and resultant changes in hydrology, it is likely that changes in marsh type may show greater variation in the future, even if given only minor changes in precipitation levels.

  7. Macromolecule mapping of the brain using ultrashort-TE acquisition and reference-based metabolite removal.

    PubMed

    Lam, Fan; Li, Yudu; Clifford, Bryan; Liang, Zhi-Pei

    2018-05-01

    To develop a practical method for mapping macromolecule distribution in the brain using ultrashort-TE MRSI data. An FID-based chemical shift imaging acquisition without metabolite-nulling pulses was used to acquire ultrashort-TE MRSI data that capture the macromolecule signals with high signal-to-noise-ratio (SNR) efficiency. To remove the metabolite signals from the ultrashort-TE data, single voxel spectroscopy data were obtained to determine a set of high-quality metabolite reference spectra. These spectra were then incorporated into a generalized series (GS) model to represent general metabolite spatiospectral distributions. A time-segmented algorithm was developed to back-extrapolate the GS model-based metabolite distribution from truncated FIDs and remove it from the MRSI data. Numerical simulations and in vivo experiments have been performed to evaluate the proposed method. Simulation results demonstrate accurate metabolite signal extrapolation by the proposed method given a high-quality reference. For in vivo experiments, the proposed method is able to produce spatiospectral distributions of macromolecules in the brain with high SNR from data acquired in about 10 minutes. We further demonstrate that the high-dimensional macromolecule spatiospectral distribution resides in a low-dimensional subspace. This finding provides a new opportunity to use subspace models for quantification and accelerated macromolecule mapping. Robustness of the proposed method is also demonstrated using multiple data sets from the same and different subjects. The proposed method is able to obtain macromolecule distributions in the brain from ultrashort-TE acquisitions. It can also be used for acquiring training data to determine a low-dimensional subspace to represent the macromolecule signals for subspace-based MRSI. Magn Reson Med 79:2460-2469, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  8. Mapping mutational effects along the evolutionary landscape of HIV envelope

    PubMed Central

    Hilton, Sarah K; Overbaugh, Julie

    2018-01-01

    The immediate evolutionary space accessible to HIV is largely determined by how single amino acid mutations affect fitness. These mutational effects can shift as the virus evolves. However, the prevalence of such shifts in mutational effects remains unclear. Here, we quantify the effects on viral growth of all amino acid mutations to two HIV envelope (Env) proteins that differ at >100 residues. Most mutations similarly affect both Envs, but the amino acid preferences of a minority of sites have clearly shifted. These shifted sites usually prefer a specific amino acid in one Env, but tolerate many amino acids in the other. Surprisingly, shifts are only slightly enriched at sites that have substituted between the Envs—and many occur at residues that do not even contact substitutions. Therefore, long-range epistasis can unpredictably shift Env’s mutational tolerance during HIV evolution, although the amino acid preferences of most sites are conserved between moderately diverged viral strains. PMID:29590010

  9. Remote sensing as a mineral prospecting technique

    NASA Technical Reports Server (NTRS)

    Meneses, P. R. (Principal Investigator)

    1984-01-01

    Remote sensing and its application as an alternative technique to mineral resource exploration are reviewed. Emphasis is given here to the analysis of the three basic attributes of remote sensing, i.e., spatial attributes related to regional structural mapping, spectral attributes related to rock discrimination and seasonal attributes related to geobotanic anomalies mapping, all of which are employed in mineral exploration. Special emphasis is given to new developments of the Thematic Mapper of the LANDSAT-5, principally with reference to the application of the bands 1.6 and 2.2 microns to map hydrothermally altered rocks and the band of red and blue shift to geobotanical anomalies mapping.

  10. Application of CPL with Interference Mapping Lithography to generate random contact reticle designs for the 65-nm node

    NASA Astrophysics Data System (ADS)

    Van Den Broeke, Douglas J.; Laidig, Thomas L.; Chen, J. Fung; Wampler, Kurt E.; Hsu, Stephen D.; Shi, Xuelong; Socha, Robert J.; Dusa, Mircea V.; Corcoran, Noel P.

    2004-08-01

    Imaging contact and via layers continues to be one of the major challenges to be overcome for 65nm node lithography. Initial results of using ASML MaskTools' CPL Technology to print contact arrays through pitch have demonstrated the potential to further extend contact imaging to a k1 near 0.30. While there are advantages and disadvantages for any potential RET, the benefits of not having to solve the phase assignment problem (which can lead to unresolvable phase conflicts), of it being a single reticle - single exposure technique, and its application to multiple layers within a device (clear field and dark field) make CPL an attractive, cost effective solution to low k1 imaging. However, real semiconductor circuit designs consist of much more than regular arrays of contact holes and a method to define the CPL reticle design for a full chip circuit pattern is required in order for this technique to be feasible in volume manufacturing. Interference Mapping Lithography (IML) is a novel approach for defining optimum reticle patterns based on the imaging conditions that will be used when the wafer is exposed. Figure 1 shows an interference map for an isolated contact simulated using ASML /1150 settings of 0.75NA and 0.92/0.72/30deg Quasar illumination. This technique provides a model-based approach for placing all types features (scattering bars, anti-scattering bars, non-printing assist features, phase shifted and non-phase shifted) for the purpose of enhancing the resolution of the target pattern and it can be applied to any reticle type including binary (COG), attenuated phase shifting mask (attPSM), alternating aperture phase shifting mask (altPSM), and CPL. In this work, we investigate the application of IML to generate CPL reticle designs for random contact patterns that are typical for 65nm node logic devices. We examine the critical issues related to using CPL with Interference Mapping Lithography including controlling side lobe printing, contact patterns with odd symmetry, forbidden pitch regions, and reticle manufacturing constraints. Multiple methods for deriving the interference map used to define reticle patterns for various RET's will be discussed. CPL reticle designs that were created from implementing automated algorithms for contact pattern decomposition using MaskWeaver will also be presented.

  11. The Atlas of Vesta Spectral Parameters derived from Dawn/VIR data

    NASA Astrophysics Data System (ADS)

    Frigeri, A.; De Sanctis, M. C.; Ammannito, E.; Tosi, F.; Zambon, F.; Capaccioni, F.; Capria, M. T.; Palomba, E.; Longobardo, A.; Fonte, S.; Giardino, M.; Magni, G.; Jaumann, R.; Raymond, C. A.; Russell, C. T.

    2013-09-01

    The Dawn mission mapped Vesta from three different orbital heights during Survey orbit (2700 km altitude), HAMO (High Altitude Mapping Orbit, 700 km altitude), and LAMO (Low Altitude Mapping Orbit, 210 km altitude) [1]. From these orbits the Dawn's Visible and Infrared Mapping Spectrometer (VIR) acquired infrared and visible spectra from 0.2 to 5 microns, sampled in 864 channels with a spatial resolution reaching about 150 m/pixel. Studies of the comparison of spectra from remote sensed data and spectra from laboratory allows to synthesize spectral parameters, which can be combined to identify specific physical and compositional states. VIR spectra of Vesta, stored in about 4300 Planetary Data System (PDS) cubes, have been analyzed to derive spectral parameters, each of which is diagnostic of the associated mineralogy on the surface of the asteroid being observed [2]. Maps of spectral parameters show terrain units compositions in their stratigraphic context. Band centers and band depths are among the most important diagnostic parameters of the mineralogy in a spectrum. In most pyroxenes and in the basaltic achondrites there is a strong correlation between the position of BI center and BII center and the associated mineralogy. For example, orthopyroxene bands shift towards longer wavelengths with increasing amounts of iron, whereas clinopyroxene bands shift towards longer wavelengths with increasing calcium content. Band depth is related to scattering effects, thus can be related to the physical state of the material.

  12. Way-finding in displaced clock-shifted bees proves bees use a cognitive map.

    PubMed

    Cheeseman, James F; Millar, Craig D; Greggers, Uwe; Lehmann, Konstantin; Pawley, Matthew D M; Gallistel, Charles R; Warman, Guy R; Menzel, Randolf

    2014-06-17

    Mammals navigate by means of a metric cognitive map. Insects, most notably bees and ants, are also impressive navigators. The question whether they, too, have a metric cognitive map is important to cognitive science and neuroscience. Experimentally captured and displaced bees often depart from the release site in the compass direction they were bent on before their capture, even though this no longer heads them toward their goal. When they discover their error, however, the bees set off more or less directly toward their goal. This ability to orient toward a goal from an arbitrary point in the familiar environment is evidence that they have an integrated metric map of the experienced environment. We report a test of an alternative hypothesis, which is that all the bees have in memory is a collection of snapshots that enable them to recognize different landmarks and, associated with each such snapshot, a sun-compass-referenced home vector derived from dead reckoning done before and after previous visits to the landmark. We show that a large shift in the sun-compass rapidly induced by general anesthesia does not alter the accuracy or speed of the homeward-oriented flight made after the bees discover the error in their initial postrelease flight. This result rules out the sun-referenced home-vector hypothesis, further strengthening the now extensive evidence for a metric cognitive map in bees.

  13. Way-finding in displaced clock-shifted bees proves bees use a cognitive map

    PubMed Central

    Cheeseman, James F.; Millar, Craig D.; Greggers, Uwe; Lehmann, Konstantin; Pawley, Matthew D. M.; Gallistel, Charles R.; Warman, Guy R.; Menzel, Randolf

    2014-01-01

    Mammals navigate by means of a metric cognitive map. Insects, most notably bees and ants, are also impressive navigators. The question whether they, too, have a metric cognitive map is important to cognitive science and neuroscience. Experimentally captured and displaced bees often depart from the release site in the compass direction they were bent on before their capture, even though this no longer heads them toward their goal. When they discover their error, however, the bees set off more or less directly toward their goal. This ability to orient toward a goal from an arbitrary point in the familiar environment is evidence that they have an integrated metric map of the experienced environment. We report a test of an alternative hypothesis, which is that all the bees have in memory is a collection of snapshots that enable them to recognize different landmarks and, associated with each such snapshot, a sun-compass–referenced home vector derived from dead reckoning done before and after previous visits to the landmark. We show that a large shift in the sun-compass rapidly induced by general anesthesia does not alter the accuracy or speed of the homeward-oriented flight made after the bees discover the error in their initial postrelease flight. This result rules out the sun-referenced home-vector hypothesis, further strengthening the now extensive evidence for a metric cognitive map in bees. PMID:24889633

  14. An empirical approach to inversion of an unconventional helicopter electromagnetic dataset

    USGS Publications Warehouse

    Pellerin, L.; Labson, V.F.

    2003-01-01

    A helicopter electromagnetic (HEM) survey acquired at the U.S. Idaho National Engineering and Environmental Laboratory (INEEL) used a modification of a traditional mining airborne method flown at low levels for detailed characterization of shallow waste sites. The low sensor height, used to increase resolution, invalidates standard assumptions used in processing HEM data. Although the survey design strategy was sound, traditional interpretation techniques, routinely used in industry, proved ineffective. Processed data and apparent resistivity maps were severely distorted, and hence unusable, due to low flight height effects, high magnetic permeability of the basalt host, and the conductive, three-dimensional nature of the waste site targets.To accommodate these interpretation challenges, we modified a one-dimensional inversion routine to include a linear term in the objective function that allows for the magnetic and three-dimensional electromagnetic responses in the in-phase data. Although somewhat ad hoc, the use of this term in the inverse routine, referred to as the shift factor, was successful in defining the waste sites and reducing noise due to the low flight height and magnetic characteristics of the host rock. Many inversion scenarios were applied to the data and careful analysis was necessary to determine the parameters appropriate for interpretation, hence the approach was empirical. Data from three areas were processed with this scheme to highlight different interpretational aspects of the method. Wastes sites were delineated with the shift terms in two of the areas, allowing for separation of the anthropomorphic targets from the natural one-dimensional host. In the third area, the estimated resistivity and the shift factor were used for geological mapping. The high magnetic content of the native soil enabled the mapping of disturbed soil with the shift term. Published by Elsevier Science B.V.

  15. Selection and quality assessment of Landsat data for the North American forest dynamics forest history maps of the US

    Treesearch

    Karen Schleeweis; Samuel N. Goward; Chengquan Huang; John L. Dwyer; Jennifer L. Dungan; Mary A. Lindsey; Andrew Michaelis; Khaldoun Rishmawi; Jeffery G. Masek

    2016-01-01

    Using the NASA Earth Exchange platform, the North American Forest Dynamics (NAFD) project mapped forest history wall-to-wall, annually for the contiguous US (1986-2010) using the Vegetation Change Tracker algorithm. As with any effort to identify real changes in remotely sensed time-series, data gaps, shifts in seasonality, misregistration, inconsistent radiometry and...

  16. Effects of dorzolamide on choroidal blood flow, ciliary blood flow, and aqueous production in rabbits.

    PubMed

    Reitsamer, Herbert A; Bogner, Barbara; Tockner, Birgit; Kiel, Jeffrey W

    2009-05-01

    To determine the effects of topical dorzolamide (a carbonic anhydrase inhibitor) on choroidal and ciliary blood flow and the relationship between ciliary blood flow and aqueous flow. The experiments were performed in four groups of pentobarbital-anesthetized rabbits treated with topical dorzolamide (2%, 50 microL). In all groups, intraocular pressure (IOP) and mean arterial pressure (MAP) at the eye level were measured continuously by direct cannulation. In group 1, aqueous flow was measured by fluorophotometry before and after dorzolamide treatment. In group 2, aqueous flow was measured after dorzolamide at normal MAP and while MAP was held constant at 80, 55, or 40 mm Hg with occluders on the aorta and vena cava. In group 3, the same MAP levels were used, and ciliary blood flow was measured transsclerally by laser Doppler flowmetry (LDF). In group 4, choroidal blood flow was measured by LDF with the probe tip positioned in the vitreous over the posterior pole during ramp increases and decreases in MAP before and after dorzolamide. Dorzolamide lowered IOP by 19% (P < 0.01) and aqueous flow by 17% (P < 0.01), and increased ciliary blood flow by 18% (P < 0.01), which was associated with a significant reduction in ciliary vasculature resistance (-7%, P < 0.01). Dorzolamide shifted the relationship between ciliary blood flow and aqueous flow downward relative to the previously determined control relationship in the rabbit. Dorzolamide did not alter choroidal blood flow, choroidal vascular resistance, or the choroidal pressure flow relationship. Acute topical dorzolamide is a ciliary vasodilator and has a direct inhibitory effect on aqueous production, but it does not have a detectable effect on choroidal hemodynamics at the posterior pole in the rabbit.

  17. Chromatic Image Analysis For Quantitative Thermal Mapping

    NASA Technical Reports Server (NTRS)

    Buck, Gregory M.

    1995-01-01

    Chromatic image analysis system (CIAS) developed for use in noncontact measurements of temperatures on aerothermodynamic models in hypersonic wind tunnels. Based on concept of temperature coupled to shift in color spectrum for optical measurement. Video camera images fluorescence emitted by phosphor-coated model at two wavelengths. Temperature map of model then computed from relative brightnesses in video images of model at those wavelengths. Eliminates need for intrusive, time-consuming, contact temperature measurements by gauges, making it possible to map temperatures on complex surfaces in timely manner and at reduced cost.

  18. Pressure mapping at orthopaedic joint interfaces with fiber Bragg gratings

    NASA Astrophysics Data System (ADS)

    Mohanty, Lipi; Tjin, Swee Chuan

    2006-02-01

    We present the concept of a fiber-optic sensor that can be used for pressure mapping at the prosthetic knee joint, in vitro and in vivo. An embedded array of fiber Bragg gratings is used to measure the load on the tibial spacer. The sensor gives the magnitude and the location of the applied load. The effect of material properties on the sensitivity of each subgrating is presented. The wavelength-shift maps show the malalignment of implants and demonstrate the potential of this sensor for use during total knee arthroplasty.

  19. Observed and Projected Droughts Conditioned on Temperature Change

    NASA Astrophysics Data System (ADS)

    Chiang, F.; AghaKouchak, A.; Mazdiyasni, O.

    2016-12-01

    Droughts have had severe urban, agricultural and wildlife impacts in historical and recent years. In addition, during times of water scarcity, heat stress has been shown to produce compounding climatic and environmental effects. Understanding the overall conditions associated with drought intensities is important for mapping the anatomy of the climate in the changing world. For the study, we evaluated the relationship drought severity has exhibited with temperature shifts between observed periods and also between an ensemble of BCSD downscaled CMIP5 projected and historically modeled datasets. We compared temperatures during different categories of drought severity on a monthly scale, and mapped areas displaying an escalation of temperature with stricter definitions of drought. A historical shift of warmer temperatures in more severe droughts was observed most consistently in Southwestern and Eastern states between the later half of the 20th century and a reference period of the early half of the 20th century. Future projections from an ensemble of CMIP5 models also showed a shift to warmer temperatures during more intense drought events in similar states. Preliminary statistics show that in many areas future droughts will be warmer that the average projected climate. These observed and forecasted shifts in the heating intensity of severe drought events underscore the need to further research these patterns and relationships both spatially and temporally.

  20. Deforestation, floodplain dynamics, and carbon biogeochemistry in the Amazon Basin

    NASA Technical Reports Server (NTRS)

    Bryan, M. L.; Dunne, T.; Richey, J.; Melack, J.; Simonett, D. S.; Woodwell, G.

    1984-01-01

    Three aspects of the physical geographic environment of the Amazon Basin are considered: (1) deforestation and reforestation, (2) floodplain dynamics, and (3) fluvial geomorphology. Three independent projects are coupled in this experiment to improve the in-place research and to ensure that the Shuttle Imaging Radar-B (SIR-B) experiment stands on a secure base of ongoing work. Major benefits to be obtained center on: (1) areal and locational information, (2) data from various depression angles, and (3) digital radar signatures. Analysis will be conducted for selected sites to define how well SIR-B data can be used for: (1) definition of extent and location of deforestation in a tropical moist forest, (2) definition and quantification of the nature of the vegetation and edaphic conditions on the (floodplain) of the Amazon River, and (3) quantification of the accuracy with which the geometry and channel shifting of the Amazon River may be mapped using SIR-B imagery in conjunction with other remote sensing data.

  1. Real-Time Correction By Optical Tracking with Integrated Geometric Distortion Correction for Reducing Motion Artifacts in fMRI

    NASA Astrophysics Data System (ADS)

    Rotenberg, David J.

    Artifacts caused by head motion are a substantial source of error in fMRI that limits its use in neuroscience research and clinical settings. Real-time scan-plane correction by optical tracking has been shown to correct slice misalignment and non-linear spin-history artifacts, however residual artifacts due to dynamic magnetic field non-uniformity may remain in the data. A recently developed correction technique, PLACE, can correct for absolute geometric distortion using the complex image data from two EPI images, with slightly shifted k-space trajectories. We present a correction approach that integrates PLACE into a real-time scan-plane update system by optical tracking, applied to a tissue-equivalent phantom undergoing complex motion and an fMRI finger tapping experiment with overt head motion to induce dynamic field non-uniformity. Experiments suggest that including volume by volume geometric distortion correction by PLACE can suppress dynamic geometric distortion artifacts in a phantom and in vivo and provide more robust activation maps.

  2. Resilient patriarchy: public authority and women's (in)security in Karamoja, Uganda.

    PubMed

    Hopwood, Julian; Porter, Holly; Saum, Nangiro

    2018-01-01

    This paper draws on fieldwork conducted in 2011 and 2016 to explore the differing experiences of Karamojong women following the Government of Uganda's most recent disarmament programme. Besides being deprived of their guns, Karamojong communities have lost most of the cattle on which their livelihoods and way of life were centred. The study assesses whether or not women's experience of patriarchy has changed in these new circumstances, and, if so, how this impacts on their security and control of resources, or the absence of them. It maps, using information primarily supplied by women, public authorities from below, and evaluates if and how they respond to women's protection and survival needs, as well as if current development/humanitarian interventions are of sustainable benefit to Karamojong women. The paper concludes that apparent shifts in gender relations are probably superficial, contingent on continuing food aid, and that economic development and positive social change for women remain elusive. © 2018 The Author(s). Disasters © Overseas Development Institute, 2018.

  3. Posttraining intraamygdala infusions of oxotremorine and propranolol modulate storage of memory for reductions in reward magnitude.

    PubMed

    Salinas, J A; Introini-Collison, I B; Dalmaz, C; McGaugh, J L

    1997-07-01

    These experiments examined the effects of posttraining intraamygdala administration of the muscarinic agonist, oxotremorine, and the beta-noradrenergic antagonist, propranolol, on memory for reduction in reward magnitude. Male Sprague-Dawley rats (175-200 g) implanted with bilateral intraamygdala cannulae were food deprived (maintained at 80% of body weight) and trained to run a straight alley (six trials/day) for either ten 45-mg food pellets (high reward) or one 45-mg food pellet (low reward) for 10 days. In Experiment One, the animals in the high-reward group were than shifted to a one-pellet reward and immediately given intraamygdala infusions (0.5 microliter/side) of either oxotremorine (10 ng) or phosphate buffer. Shifted training continued for 4 more days and no further injections were given. Shifted animals given the buffer solution displayed an increase in runway latencies but returned to preshift latencies by the fifth day of shifted training. In contrast, animals given oxotremorine exhibited increased latencies through the fifth day. In Experiment Two, rats were trained as in Experiment. One but immediately following the shift received intraamygdala infusions of oxotremorine (10 ng), propranolol (0.3 microgram), both, or phosphate buffer. Shifted vehicle-injected rats returned to preshift performance by the fifth day of shifted training. Shifted propranolol rats returned to preshift latencies by the third day of shifted training. In contrast, the shifted oxotremorine and the shifted oxotremorine/propranolol rats displayed longer latencies than unshifted controls through 5 days of shifted training. The findings indicate that the muscarinic cholinergic and beta-noradrenergic systems within the amygdala interact in regulating memory and support the view that noradrenergic influences are mediated through cholinergic activation.

  4. Molecular jet of IRAS 04166+2706

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Liang-Yao; Shang, Hsien; Su, Yu-Nung

    2014-01-01

    The molecular outflow from IRAS 04166+2706 was mapped with the Submillimeter Array at a 350 GHz continuum and CO J = 3-2 at an angular resolution of ∼1''. The field of view covers the central arcminute, which contains the inner four pairs of knots of the molecular jet. On the channel map, conical structures are clearly present in the low-velocity range (|V – V {sub 0}| < 10 km s{sup –1}), and the highly collimated knots appear in the extremely high velocity range (50 >|V – V {sub 0}| > 30 km s{sup –1}). The higher angular resolution of ∼1''more » reveals the first blue-shifted knot (B1) that was missing in previous Plateau de Bure Interferometer observation of Santiago-García et al. at an offset of ∼6'' to the northeast of the central source. This identification completes the symmetric sequence of knots in both the blue- and red-shifted lobes of the outflow. The innermost knots R1 and B1 have the highest velocities within the sequence. Although the general features appear to be similar to previous CO J = 2-1 images in Santiago-García et al., the emission in CO J = 3-2 almost always peaks further away from the central source than that of CO J = 2-1 in the red-shifted lobe of the channel maps. This gives rise to a gradient in the line-ratio map of CO J = 3-2/J = 2-1 from head to tail within a knot. A large velocity gradient analysis suggests that the differences may reflect a higher gas kinetic temperature at the head. We also explore possible constraints imposed by the nondetection of SiO J = 8-7.« less

  5. Mapping variations in weight percent silica measured from multispectral thermal infrared imagery - Examples from the Hiller Mountains, Nevada, USA and Tres Virgenes-La Reforma, Baja California Sur, Mexico

    USGS Publications Warehouse

    Hook, S.J.; Dmochowski, J.E.; Howard, K.A.; Rowan, L.C.; Karlstrom, K.E.; Stock, J.M.

    2005-01-01

    Remotely sensed multispectral thermal infrared (8-13 ??m) images are increasingly being used to map variations in surface silicate mineralogy. These studies utilize the shift to longer wavelengths in the main spectral feature in minerals in this wavelength region (reststrahlen band) as the mineralogy changes from felsic to mafic. An approach is described for determining the amount of this shift and then using the shift with a reference curve, derived from laboratory data, to remotely determine the weight percent SiO2 of the surface. The approach has broad applicability to many study areas and can also be fine-tuned to give greater accuracy in a particular study area if field samples are available. The approach was assessed using airborne multispectral thermal infrared images from the Hiller Mountains, Nevada, USA and the Tres Virgenes-La Reforma, Baja California Sur, Mexico. Results indicate the general approach slightly overestimates the weight percent SiO2 of low silica rocks (e.g. basalt) and underestimates the weight percent SiO2 of high silica rocks (e.g. granite). Fine tuning the general approach with measurements from field samples provided good results for both areas with errors in the recovered weight percent SiO2 of a few percent. The map units identified by these techniques and traditional mapping at the Hiller Mountains demonstrate the continuity of the crystalline rocks from the Hiller Mountains southward to the White Hills supporting the idea that these ranges represent an essentially continuous footwall block below a regional detachment. Results from the Baja California data verify the most recent volcanism to be basaltic-andesite. ?? 2005 Elsevier Inc. All rights reserved.

  6. Path length dependent neutron diffraction peak shifts observed during residual strain measurements in U–8 wt% Mo castings

    DOE PAGES

    Steiner, M. A.; Bunn, J. R.; Einhorn, J. R.; ...

    2017-05-16

    This study reports an angular diffraction peak shift that scales linearly with the neutron beam path length traveled through a diffracting sample. This shift was observed in the context of mapping the residual stress state of a large U–8 wt% Mo casting, as well as during complementary measurements on a smaller casting of the same material. If uncorrected, this peak shift implies a non-physical level of residual stress. A hypothesis for the origin of this shift is presented, based upon non-ideal focusing of the neutron monochromator in combination with changes to the wavelength distribution reaching the detector due to factorsmore » such as attenuation. The magnitude of the shift is observed to vary linearly with the width of the diffraction peak reaching the detector. Consideration of this shift will be important for strain measurements requiring long path lengths through samples with significant attenuation. This effect can probably be reduced by selecting smaller voxel slit widths.« less

  7. White light phase shifting interferometry and color fringe analysis for the detection of contaminants in water

    NASA Astrophysics Data System (ADS)

    Dubey, Vishesh; Singh, Veena; Ahmad, Azeem; Singh, Gyanendra; Mehta, Dalip Singh

    2016-03-01

    We report white light phase shifting interferometry in conjunction with color fringe analysis for the detection of contaminants in water such as Escherichia coli (E.coli), Campylobacter coli and Bacillus cereus. The experimental setup is based on a common path interferometer using Mirau interferometric objective lens. White light interferograms are recorded using a 3-chip color CCD camera based on prism technology. The 3-chip color camera have lesser color cross talk and better spatial resolution in comparison to single chip CCD camera. A piezo-electric transducer (PZT) phase shifter is fixed with the Mirau objective and they are attached with a conventional microscope. Five phase shifted white light interferograms are recorded by the 3-chip color CCD camera and each phase shifted interferogram is decomposed into the red, green and blue constituent colors, thus making three sets of five phase shifted intererograms for three different colors from a single set of white light interferogram. This makes the system less time consuming and have lesser effect due to surrounding environment. Initially 3D phase maps of the bacteria are reconstructed for red, green and blue wavelengths from these interferograms using MATLAB, from these phase maps we determines the refractive index (RI) of the bacteria. Experimental results of 3D shape measurement and RI at multiple wavelengths will be presented. These results might find applications for detection of contaminants in water without using any chemical processing and fluorescent dyes.

  8. Development and evaluation of a specialized task taxonomy for spatial planning - A map literacy experiment with topographic maps

    NASA Astrophysics Data System (ADS)

    Rautenbach, Victoria; Coetzee, Serena; Çöltekin, Arzu

    2017-05-01

    Topographic maps are among the most commonly used map types, however, their complex and information-rich designs depicting natural, human-made and cultural features make them difficult to read. Regardless of their complexity, spatial planners make extensive use of topographic maps in their work. On the other hand, various studies suggest that map literacy among the development planning professionals in South Africa is not very high. The widespread use of topographic maps combined with the low levels of map literacy presents challenges for effective development planning. In this paper we address some of these challenges by developing a specialized task taxonomy based on systematically assessed map literacy levels; and conducting an empirical experiment with topographic maps to evaluate our task taxonomy. In such empirical studies if non-realistic tasks are used, the results of map literacy tests may be skewed. Furthermore, experience and familiarity with the studied map type play a role in map literacy. There is thus a need to develop map literacy tests aimed at planners specifically. We developed a taxonomy of realistic map reading tasks typically executed during the planning process. The taxonomy defines six levels tasks of increasing difficulty and complexity, ranging from recognising symbols to extracting knowledge. We hypothesized that competence in the first four levels indicates functional map literacy. In this paper, we present results from an empirical experiment with 49 map literate participants solving a subset of tasks from the first four levels of the taxonomy with a topographic map. Our findings suggest that the proposed taxonomy is a good reference for evaluating topographic map literacy. Participants solved the tasks on all four levels as expected and we therefore conclude that the experiment based on the first four levels of the taxonomy successfully determined the functional map literacy of the participants. We plan to continue the study for the remaining levels, repeat the experiments with a group of map illiterate participants to confirm that the taxonomy can also be used to determine map illiteracy.

  9. Phytoplankton Cell Size: Intra- and Interspecific Effects of Warming and Grazing

    PubMed Central

    Peter, Kalista Higini; Sommer, Ulrich

    2012-01-01

    Decreasing body size has been suggested as the third universal biological response to global warming after latitudinal/altitudinal range shifts and shifts in phenology. Size shifts in a community can be the composite result of intraspecific size shifts and of shifts between differently sized species. Metabolic explanations for the size shifts dominate in the literature but top down effects, i.e. intensified size-selective consumption at higher temperatures, have been proposed as alternative explanation. Therefore, we performed phytoplankton experiments with a factorial combination of warming and consumer type (protist feeding mainly on small algae vs. copepods mainly feeding on large algae). Natural phytoplankton was exposed to 3 (1st experiment) or 4 (2nd experiment) temperature levels and 3 (1st experiment: nano-, microzooplankton, copepods) or 2 (2nd experiment: microzooplankton, copepods) types of consumers. Size shifts of individual phytoplankton species and community mean size were analyzed. Both, mean cell size of most of the individual species and mean community cell size decreased with temperature under all grazing regimes. Grazing by copepods caused an additional reduction in cell size. Our results reject the hypothesis, that intensified size selective consumption at higher temperature would be the dominant explanation of decreasing body size. In this case, the size reduction would have taken place only in the copepod treatments but not in the treatments with protist grazing (nano- and microzooplankton). PMID:23226215

  10. Strength-based criterion shifts in recognition memory.

    PubMed

    Singer, Murray

    2009-10-01

    In manipulations of stimulus strength between lists, a more lenient signal detection criterion is more frequently applied to a weak than to a strong stimulus class. However, with randomly intermixed weak and strong test probes, such a criterion shift often does not result. A procedure that has yielded delay-based within-list criterion shifts was applied to strength manipulations in recognition memory for categorized word lists. When participants made semantic ratings about each stimulus word, strength-based criterion shifts emerged regardless of whether words from pairs of categories were studied in separate blocks (Experiment 1) or in intermixed blocks (Experiment 2). In Experiment 3, the criterion shift persisted under the semantic-rating study task, but not under rote memorization. These findings suggest that continually adjusting the recognition decision criterion is cognitively feasible. They provide a technique for manipulating the criterion shift, and they identify competing theoretical accounts of these effects.

  11. Using parallel banded linear system solvers in generalized eigenvalue problems

    NASA Technical Reports Server (NTRS)

    Zhang, Hong; Moss, William F.

    1993-01-01

    Subspace iteration is a reliable and cost effective method for solving positive definite banded symmetric generalized eigenproblems, especially in the case of large scale problems. This paper discusses an algorithm that makes use of two parallel banded solvers in subspace iteration. A shift is introduced to decompose the banded linear systems into relatively independent subsystems and to accelerate the iterations. With this shift, an eigenproblem is mapped efficiently into the memories of a multiprocessor and a high speed-up is obtained for parallel implementations. An optimal shift is a shift that balances total computation and communication costs. Under certain conditions, we show how to estimate an optimal shift analytically using the decay rate for the inverse of a banded matrix, and how to improve this estimate. Computational results on iPSC/2 and iPSC/860 multiprocessors are presented.

  12. Stability and instability for low refractive-index-contrast particle trapping in a dual-beam optical trap.

    PubMed

    Huff, Alison; Melton, Charles N; Hirst, Linda S; Sharping, Jay E

    2015-10-01

    A dual-beam optical trap is used to trap and manipulate dielectric particles. When the refractive index of these particles is comparable to that of the surrounding medium, equilibrium trapping locations within the system shift from stable to unstable depending on fiber separation and particle size. This is due to to the relationship between gradient and scattering forces. We experimentally and computationally study the transitions between stable and unstable trapping of poly(methyl methacrylate) beads for a range of parameters relevant to experimental setups involving giant unilamellar vesicles. We present stability maps for various fiber separations and particle sizes, and find that careful attention to particle size and configuration is necessary to obtain reproducible quantitative results for soft matter stretching experiments.

  13. Stability and instability for low refractive-index-contrast particle trapping in a dual-beam optical trap

    PubMed Central

    Huff, Alison; Melton, Charles N.; Hirst, Linda S.; Sharping, Jay E.

    2015-01-01

    A dual-beam optical trap is used to trap and manipulate dielectric particles. When the refractive index of these particles is comparable to that of the surrounding medium, equilibrium trapping locations within the system shift from stable to unstable depending on fiber separation and particle size. This is due to to the relationship between gradient and scattering forces. We experimentally and computationally study the transitions between stable and unstable trapping of poly(methyl methacrylate) beads for a range of parameters relevant to experimental setups involving giant unilamellar vesicles. We present stability maps for various fiber separations and particle sizes, and find that careful attention to particle size and configuration is necessary to obtain reproducible quantitative results for soft matter stretching experiments. PMID:26504632

  14. Pixel-based absolute surface metrology by three flat test with shifted and rotated maps

    NASA Astrophysics Data System (ADS)

    Zhai, Dede; Chen, Shanyong; Xue, Shuai; Yin, Ziqiang

    2018-03-01

    In traditional three flat test, it only provides the absolute profile along one surface diameter. In this paper, an absolute testing algorithm based on shift-rotation with three flat test has been proposed to reconstruct two-dimensional surface exactly. Pitch and yaw error during shift procedure is analyzed and compensated in our method. Compared with multi-rotation method proposed before, it only needs a 90° rotation and a shift, which is easy to carry out especially in condition of large size surface. It allows pixel level spatial resolution to be achieved without interpolation or assumption to the test surface. In addition, numerical simulations and optical tests are implemented and show the high accuracy recovery capability of the proposed method.

  15. Fat water decomposition using globally optimal surface estimation (GOOSE) algorithm.

    PubMed

    Cui, Chen; Wu, Xiaodong; Newell, John D; Jacob, Mathews

    2015-03-01

    This article focuses on developing a novel noniterative fat water decomposition algorithm more robust to fat water swaps and related ambiguities. Field map estimation is reformulated as a constrained surface estimation problem to exploit the spatial smoothness of the field, thus minimizing the ambiguities in the recovery. Specifically, the differences in the field map-induced frequency shift between adjacent voxels are constrained to be in a finite range. The discretization of the above problem yields a graph optimization scheme, where each node of the graph is only connected with few other nodes. Thanks to the low graph connectivity, the problem is solved efficiently using a noniterative graph cut algorithm. The global minimum of the constrained optimization problem is guaranteed. The performance of the algorithm is compared with that of state-of-the-art schemes. Quantitative comparisons are also made against reference data. The proposed algorithm is observed to yield more robust fat water estimates with fewer fat water swaps and better quantitative results than other state-of-the-art algorithms in a range of challenging applications. The proposed algorithm is capable of considerably reducing the swaps in challenging fat water decomposition problems. The experiments demonstrate the benefit of using explicit smoothness constraints in field map estimation and solving the problem using a globally convergent graph-cut optimization algorithm. © 2014 Wiley Periodicals, Inc.

  16. All-optical mapping of barrel cortex circuits based on simultaneous voltage-sensitive dye imaging and channelrhodopsin-mediated photostimulation

    PubMed Central

    Lo, Shun Qiang; Koh, Dawn X. P.; Sng, Judy C. G.; Augustine, George J.

    2015-01-01

    Abstract. We describe an experimental approach that uses light to both control and detect neuronal activity in mouse barrel cortex slices: blue light patterned by a digital micromirror array system allowed us to photostimulate specific layers and columns, while a red-shifted voltage-sensitive dye was used to map out large-scale circuit activity. We demonstrate that such all-optical mapping can interrogate various circuits in somatosensory cortex by sequentially activating different layers and columns. Further, mapping in slices from whisker-deprived mice demonstrated that chronic sensory deprivation did not significantly alter feedforward inhibition driven by layer 5 pyramidal neurons. Further development of voltage-sensitive optical probes should allow this all-optical mapping approach to become an important and high-throughput tool for mapping circuit interactions in the brain. PMID:26158003

  17. Mapping cerebrovascular reactivity using concurrent fMRI and near infrared spectroscopy

    NASA Astrophysics Data System (ADS)

    Tong, Yunjie; Bergethon, Peter R.; Frederick, Blaise d.

    2011-02-01

    Cerebrovascular reactivity (CVR) reflects the compensatory dilatory capacity of cerebral vasculature to a dilatory stimulus and is an important indicator of brain vascular reserve. fMRI has been proven to be an effective imaging technique to obtain the CVR map when the subjects perform CO2 inhalation or the breath holding task (BH). However, the traditional data analysis inaccurately models the BOLD using a boxcar function with fixed time delay. We propose a novel way to process the fMRI data obtained during a blocked BH by using the simultaneously collected near infrared spectroscopy (NIRS) data as regressor1. In this concurrent NIRS and fMRI study, 6 healthy subjects performed a blocked BH (5 breath holds with 20s durations intermitted by 40s of regular breathing). A NIRS probe of two sources and two detectors separated by 3 cm was placed on the right side of prefrontal area of the subjects. The time course of changes in oxy-hemoglobin (Δ[HbO]) was calculated from NIRS data and shifted in time by various amounts, and resampled to the fMRI acquisition rate. Each shifted time course was used as regressor in FEAT (the analysis tool in FSL). The resulting z-statistic maps were concatenated in time and the maximal value was taken along the time for all the voxels to generate a 3-D CVR map. The new method produces more accurate and thorough CVR maps; moreover, it enables us to produce a comparable baseline cerebral vascular map if applied to resting state (RS) data.

  18. Self-assessed quality of sleep, occupational health, working environment, illness experience and job satisfaction of female nurses working different combination of shifts.

    PubMed

    Sveinsdóttir, Herdis

    2006-06-01

    The aim of this study was to describe and compare the self-assessed quality of sleep, occupational health, working environment, illness experience and job satisfaction among female nurses working different combinations of shifts. Evidence from several studies indicates that there is an association between the disruption of the circadian cycle caused by shift work and adverse health effects. A cross-sectional design was used with a sample of 348 nurses drawn from the registry of the Icelandic Nurses' Association, representing 17% of the workforce of Icelandic nurses. A self-administered questionnaire, measuring occupational health, quality of sleep, the illness experience, job satisfaction and working environment was used. Data were analysed according to type of shift (days only, rotating days/evenings, rotating days/evenings/nights) by use of analysis of variance and chi-square. No difference was found between participants based on type of shift with regard to the illness experience, job satisfaction and quality of sleep. Nurses working rotating day/evening/night shifts reported a longer working day, more stressful environmental risk factors, more strenuous work and that they were less able to control their work-pace. In general, the nurses reported low severity of symptoms; however, nurses working rotating days/evenings shifts experienced more severe gastrointestinal and musculoskeletal symptoms when compared with others. This was explained by the short rest period provided for between evening and morning shifts. In general Icelandic nurses are satisfied with their work and their shift assignment does not seem to pathologically disrupt their circadian cycle. Nevertheless, nursing directors are advised to look more closely at the organization of nurses' work during night shifts, as well as the rest period for nurses changing from evening to day shifts.

  19. Effect of angular velocity on sensors based on morphology dependent resonances.

    PubMed

    Ali, Amir R; Ioppolo, Tindaro

    2014-04-22

    We carried out an analysis to investigate the morphology dependent optical resonances shift (MDR) of a rotating spherical resonator. The spinning resonator experiences an elastic deformation due to the centrifugal force acting on it, leading to a shift in its MDR. Experiments are also carried out to demonstrate the MDR shifts of a spinning polydimethylsiloxane (PDMS) microsphere. The experimental results agree well with the analytical prediction. These studies demonstrated that spinning sensor based on MDR may experience sufficient shift in the optical resonances, therefore interfering with its desirable operational sensor design. Also the results show that angular velocity sensors could be designed using this principle.

  20. A synopsis of X-band radar-derived results from New River Inlet, NC (May 2012): Wave transformation, bathymetry, and tidal currents

    NASA Astrophysics Data System (ADS)

    Honegger, D. A.; Haller, M. C.; Diaz Mendez, G. M.; Pittman, R.; Catalan, P. A.

    2012-12-01

    Land-based X-band marine radar observations were collected as part of the month-long DARLA-MURI / RIVET-DRI field experiment at New River Inlet, NC in May 2012. Here we present a synopsis of preliminary results utilizing microwave radar backscatter time series collected from an antenna located 400 m inside the inlet mouth and with a footprint spanning 1000 m beyond the ebb shoals. Two crucial factors in the forcing and constraining of nearshore numerical models are accurate bathymetry and offshore variability in the wave field. Image time series of radar backscatter from surface gravity waves can be utilized to infer these parameters over a large swath and during times of poor optical visibility. Presented are radar-derived wavenumber vector maps obtained from the Plant et al. (2008) algorithm and bathymetric estimates as calculated using Holman et al. (JGR, in review). We also evaluate the effects of tidal currents on the wave directions and depth inversion accuracy. In addition, shifts in the average wave breaking patterns at tidal frequencies shed light on depth- (and possibly current-) induced breaking as a function of tide level and tidal current velocity, while shifts over longer timescales imply bedform movement during the course of the experiment. Lastly, lowpass filtered radar image time series of backscatter intensity are shown to identify the structure and propagation of tidal plume fronts and multiscale ebb jets at the offshore shoal boundary.

  1. Hippocampal participation in navigational map learning in young homing pigeons is dependent on training experience.

    PubMed

    Ioalè, P; Gagliardo, A; Bingman, V P

    2000-02-01

    The homing pigeon navigational map is perhaps one of the most striking examples of a naturally occurring spatial representation of the environment used to guide navigation. In a previous study, it was found that hippocampal lesions thoroughly disrupt the ability of young homing pigeons held in an outdoor aviary to learn a navigational map. However, since that study an accumulation of anecdotal data has hinted that hippocampal-lesioned young pigeons allowed to fly during their first summer could learn a navigational map. In the present study, young control and hippocampal-lesioned homing pigeons were either held in an outdoor aviary or allowed to fly during the time of navigational map learning. At the end of their first summer, the birds were experimentally released to test for navigational map learning. Independent of training experience, control pigeons oriented homeward during the experimental releases demonstrating that they learned a navigational map. Surprisingly, while the aviary-held hippocampal-lesioned pigeons failed to learn a navigational map as reported previously, hippocampal-lesioned birds allowed flight experience learned a navigational map indistinguishable from the two control groups. A subsequent experiment revealed that the navigational map learned by the three groups was based on atmospheric odours. The results demonstrate that hippocampal participation in navigational map learning depends on the type of experience a young bird pigeon has, and presumably, the type of navigational map learned.

  2. A Fast Variant of 1H Spectroscopic U-FLARE Imaging Using Adjusted Chemical Shift Phase Encoding

    NASA Astrophysics Data System (ADS)

    Ebel, Andreas; Dreher, Wolfgang; Leibfritz, Dieter

    2000-02-01

    So far, fast spectroscopic imaging (SI) using the U-FLARE sequence has provided metabolic maps indirectly via Fourier transformation (FT) along the chemical shift (CS) dimension and subsequent peak integration. However, a large number of CS encoding steps Nω is needed to cover the spectral bandwidth and to achieve sufficient spectral resolution for peak integration even if the number of resonance lines is small compared to Nω and even if only metabolic images are of interest and not the spectra in each voxel. Other reconstruction algorithms require extensive prior knowledge, starting values, and/or model functions. An adjusted CS phase encoding scheme (APE) can be used to overcome these drawbacks. It incorporates prior knowledge only about the resonance frequencies present in the sample. Thus, Nω can be reduced by a factor of 4 for many 1H in vivo studies while no spectra have to be reconstructed, and no additional user interaction, prior knowledge, starting values, or model function are required. Phantom measurements and in vivo experiments on rat brain have been performed at 4.7 T to test the feasibility of the method for proton SI.

  3. Telecentric 3D profilometry based on phase-shifting fringe projection.

    PubMed

    Li, Dong; Liu, Chunyang; Tian, Jindong

    2014-12-29

    Three dimensional shape measurement in the microscopic range becomes increasingly important with the development of micro manufacturing technology. Microscopic fringe projection techniques offer a fast, robust, and full-field measurement for field sizes from approximately 1 mm2 to several cm2. However, the depth of field is very small due to the imaging of non-telecentric microscope, which is often not sufficient to measure the complete depth of a 3D-object. And the calibration of phase-to-depth conversion is complicated which need a precision translation stage and a reference plane. In this paper, we propose a novel telecentric phase-shifting projected fringe profilometry for small and thick objects. Telecentric imaging extends the depth of field approximately to millimeter order, which is much larger than that of microscopy. To avoid the complicated phase-to-depth conversion in microscopic fringe projection, we develop a new system calibration method of camera and projector based on telecentric imaging model. Based on these, a 3D reconstruction of telecentric imaging is presented with stereovision aided by fringe phase maps. Experiments demonstrated the feasibility and high measurement accuracy of the proposed system for thick object.

  4. Shifted Transversal Design smart-pooling for high coverage interactome mapping

    PubMed Central

    Xin, Xiaofeng; Rual, Jean-François; Hirozane-Kishikawa, Tomoko; Hill, David E.; Vidal, Marc; Boone, Charles; Thierry-Mieg, Nicolas

    2009-01-01

    “Smart-pooling,” in which test reagents are multiplexed in a highly redundant manner, is a promising strategy for achieving high efficiency, sensitivity, and specificity in systems-level projects. However, previous applications relied on low redundancy designs that do not leverage the full potential of smart-pooling, and more powerful theoretical constructions, such as the Shifted Transversal Design (STD), lack experimental validation. Here we evaluate STD smart-pooling in yeast two-hybrid (Y2H) interactome mapping. We employed two STD designs and two established methods to perform ORFeome-wide Y2H screens with 12 baits. We found that STD pooling achieves similar levels of sensitivity and specificity as one-on-one array-based Y2H, while the costs and workloads are divided by three. The screening-sequencing approach is the most cost- and labor-efficient, yet STD identifies about twofold more interactions. Screening-sequencing remains an appropriate method for quickly producing low-coverage interactomes, while STD pooling appears as the method of choice for obtaining maps with higher coverage. PMID:19447967

  5. Mapping the absolute magnetic field and evaluating the quadratic Zeeman-effect-induced systematic error in an atom interferometer gravimeter

    NASA Astrophysics Data System (ADS)

    Hu, Qing-Qing; Freier, Christian; Leykauf, Bastian; Schkolnik, Vladimir; Yang, Jun; Krutzik, Markus; Peters, Achim

    2017-09-01

    Precisely evaluating the systematic error induced by the quadratic Zeeman effect is important for developing atom interferometer gravimeters aiming at an accuracy in the μ Gal regime (1 μ Gal =10-8m /s2 ≈10-9g ). This paper reports on the experimental investigation of Raman spectroscopy-based magnetic field measurements and the evaluation of the systematic error in the gravimetric atom interferometer (GAIN) due to quadratic Zeeman effect. We discuss Raman duration and frequency step-size-dependent magnetic field measurement uncertainty, present vector light shift and tensor light shift induced magnetic field measurement offset, and map the absolute magnetic field inside the interferometer chamber of GAIN with an uncertainty of 0.72 nT and a spatial resolution of 12.8 mm. We evaluate the quadratic Zeeman-effect-induced gravity measurement error in GAIN as 2.04 μ Gal . The methods shown in this paper are important for precisely mapping the absolute magnetic field in vacuum and reducing the quadratic Zeeman-effect-induced systematic error in Raman transition-based precision measurements, such as atomic interferometer gravimeters.

  6. Surface Information Loss in Comprehension

    PubMed Central

    Gernsbacher, Morton Ann

    2014-01-01

    Shortly after a sentence has been comprehended, information about its exact surface form (e.g., its word order) becomes less available. The present research demonstrated this phenomenon during the comprehension of nonverbal stimuli (picture stories). In Experiment 1, significantly more surface (left/right orientation) information was lost after comprehending several picture stories than just one; in Experiment 2, more was lost after comprehending an entire picture story than half of one. In Experiment 3, subjects segmented the picture stories into their constituents; in Experiment 4, significantly more surface information was lost after crossing these constituents’ boundaries than before. The present research also investigated why surface information is lost. Four explanations were considered: Surface information loss is the result of performing grammatical transformations (the linguistic hypothesis), exceeding short-term memory limitations (the memory limitations hypothesis), integrating information into gist (the integration hypothesis), shifting from building one substructure to initiating another (the processing shift hypothesis). The linguistic and memory limitations hypotheses were considered inadequate; the integration and the processing shift hypotheses were tested in the last set of experiments. In Experiment 5 (using nonverbal stimuli), the predictions made by the processing shift hypothesis were confirmed; in Experiment 6 (using verbal stimuli), these results were replicated. Other implications of the processing shift hypothesis concerning surface information loss are discussed. PMID:25308975

  7. Ecosystem service provision in a changing Europe: adapting to the impacts of combined climate and socio-economic change.

    PubMed

    Dunford, Robert W; Smith, Alison C; Harrison, Paula A; Hanganu, Diana

    Future patterns of European ecosystem services provision are likely to vary significantly as a result of climatic and socio-economic change and the implementation of adaptation strategies. However, there is little research in mapping future ecosystem services and no integrated assessment approach to map the combined impacts of these drivers. Map changing patterns in ecosystem services for different European futures and (a) identify the role of driving forces; (b) explore the potential influence of different adaptation options. The CLIMSAVE integrated assessment platform is used to map spatial patterns in services (food, water and timber provision, atmospheric regulation, biodiversity existence/bequest, landscape experience and land use diversity) for a number of combined climatic and socio-economic scenarios. Eight adaptation strategies are explored within each scenario. Future service provision (particularly water provision) will be significantly impacted by climate change. Socio-economic changes shift patterns of service provision: more dystopian societies focus on food provision at the expense of other services. Adaptation options offer significant opportunities, but may necessitate trade-offs between services, particularly between agriculture- and forestry-related services. Unavoidable trade-offs between regions (particularly South-North) are also identified in some scenarios. Coordinating adaptation across regions and sectors will be essential to ensure that all needs are met: a factor that will become increasingly pressing under dystopian futures where inter-regional cooperation breaks down. Integrated assessment enables exploration of interactions and trade-offs between ecosystem services, highlighting the importance of taking account of complex cross-sectoral interactions under different future scenarios of planning adaptation responses.

  8. AGN Space Telescope and Optical Reverberation Mapping Project. IV. Velocity-Delay Mapping of Broad Emission Lines in NGC 5548

    NASA Astrophysics Data System (ADS)

    Horne, Keith D.; Agn Storm Team

    2015-01-01

    Two-dimensional velocity-delay maps of AGN broad emission line regions can be recovered by modelling observations of reverberating emission-line profiles on the assumption that the line profile variations are driven by changes in ionising radiation from a compact source near the black hole. The observable light travel time delay resolves spatial structure on iso-delay paraboloids, while the doppler shift resolves kinematic structure along the observer's line-of-sight. Velocity-delay maps will be presented and briefly discussed for the Lyman alpha, CIV and Hbeta line profiles based on the HST and ground-based spectrophotometric monitoring of NGC 5548 during the 2014 AGN STORM campaign.

  9. The Modality Shift Experiment in Adults and Children with High Functioning Autism

    ERIC Educational Resources Information Center

    Williams, Diane L.; Goldstein, Gerald; Minshew, Nancy J.

    2013-01-01

    This study used the modality shift experiment, a relatively simple reaction time measure to visual and auditory stimuli, to examine attentional shifting within and across modalities in 33 children and 42 adults with high-functioning autism as compared to matched numbers of age- and ability-matched typical controls. An exaggerated "modality shift…

  10. The Effect of Modality Shifts on Practive Interference in Long-Term Memory.

    ERIC Educational Resources Information Center

    Dean, Raymond S.; And Others

    1983-01-01

    In experiment one, subjects learned a word list in blocked or random forms of auditory/visual change. In experiment two, high- and low-conceptual rigid subjects read passages in shift conditions or nonshift, exclusively in auditory or visual modes. A shift in modality provided a powerful release from proactive interference. (Author/CM)

  11. Conceptual change in pre-service science teachers' views on nature of science when learning a unit on the physics of waves

    NASA Astrophysics Data System (ADS)

    Kattoula, Ehsan Habib

    Recent reform efforts in science education have culminated in National Science Education Standards (NSES), which include the nature of science and science inquiry themes across all grade levels. Consideration must be given to pre-service science teachers' nature of science conceptions and their perceived roles in implementing the nature of science in the science classroom. This qualitative study investigates how pre-service science teachers' views about the nature of science develop and change when learning a college physics unit on waves in an urban university. The study uses case study methodology with four pre-service science teachers as individual units of analysis. Data regarding the participants' views about the nature of science were collected before and after the instruction on the physics of waves unit. The research design used 'The Views of Nature of Science/Views of Scientific Inquiry-Physics Questionnaire' followed by structured interviews throughout the wave unit. In addition, the participants responded to daily questions that incorporated nature of science themes and constructed concept maps regarding the physics content and their nature of science understanding. After completing the VNOS/VOSI-PHYS questionnaire the pre-service science teachers' views of the nature of science were found to be mainly naive and transitional before the instruction. At the end of the wave unit instruction, the data indicated that conceptual change occurred in participants' nature of science views, shifting toward informed views. The findings of this study provide evidence that using explicit instruction with specific activities, such as experiments and concept mapping, shifted the pre-service science teachers' views away from naive and toward informed.

  12. The target-to-foils shift in simultaneous and sequential lineups.

    PubMed

    Clark, Steven E; Davey, Sherrie L

    2005-04-01

    A theoretical cornerstone in eyewitness identification research is the proposition that witnesses, in making decisions from standard simultaneous lineups, make relative judgments. The present research considers two sources of support for this proposal. An experiment by G. L. Wells (1993) showed that if the target is removed from a lineup, witnesses shift their responses to pick foils, rather than rejecting the lineups, a result we will term a target-to-foils shift. Additional empirical support is provided by results from sequential lineups which typically show higher accuracy than simultaneous lineups, presumably because of a decrease in the use of relative judgments in making identification decisions. The combination of these two lines of research suggests that the target-to-foils shift should be reduced in sequential lineups relative to simultaneous lineups. Results of two experiments showed an overall advantage for sequential lineups, but also showed a target-to-foils shift equal in size for simultaneous and sequential lineups. Additional analyses indicated that the target-to-foils shift in sequential lineups was moderated in part by an order effect and was produced with (Experiment 2) or without (Experiment 1) a shift in decision criterion. This complex pattern of results suggests that more work is needed to understand the processes which underlie decisions in simultaneous and sequential lineups.

  13. The ALICE Glance Shift Accounting Management System (SAMS)

    NASA Astrophysics Data System (ADS)

    Martins Silva, H.; Abreu Da Silva, I.; Ronchetti, F.; Telesca, A.; Maidantchik, C.

    2015-12-01

    ALICE (A Large Ion Collider Experiment) is an experiment at the CERN LHC (Large Hadron Collider) studying the physics of strongly interacting matter and the quark-gluon plasma. The experiment operation requires a 24 hours a day and 7 days a week shift crew at the experimental site, composed by the ALICE collaboration members. Shift duties are calculated for each institute according to their correlated members. In order to ensure the full coverage of the experiment operation as well as its good quality, the ALICE Shift Accounting Management System (SAMS) is used to manage the shift bookings as well as the needed training. ALICE SAMS is the result of a joint effort between the Federal University of Rio de Janeiro (UFRJ) and the ALICE Collaboration. The Glance technology, developed by the UFRJ and the ATLAS experiment, sits at the basis of the system as an intermediate layer isolating the particularities of the databases. In this paper, we describe the ALICE SAMS development process and functionalities. The database has been modelled according to the collaboration needs and is fully integrated with the ALICE Collaboration repository to access members information and respectively roles and activities. Run, period and training coordinators can manage their subsystem operation and ensure an efficient personnel management. Members of the ALICE collaboration can book shifts and on-call according to pre-defined rights. ALICE SAMS features a user profile containing all the statistics and user contact information as well as the Institutes profile. Both the user and institute profiles are public (within the scope of the collaboration) and show the credit balance in real time. A shift calendar allows the Run Coordinator to plan data taking periods in terms of which subsystems shifts are enabled or disabled and on-call responsible people and slots. An overview display presents the shift crew present in the control room and allows the Run Coordination team to confirm the presence of both regular and trainees shift personnel, necessary for credit accounting.

  14. Present and Future of Dengue Fever in Nepal: Mapping Climatic Suitability by Ecological Niche Model

    PubMed Central

    Cao, Chunxiang; Xu, Min; Pandit, Shreejana

    2018-01-01

    Both the number of cases of dengue fever and the areas of outbreaks within Nepal have increased significantly in recent years. Further expansion and range shift is expected in the future due to global climate change and other associated factors. However, due to limited spatially-explicit research in Nepal, there is poor understanding about the present spatial distribution patterns of dengue risk areas and the potential range shift due to future climate change. In this context, it is crucial to assess and map dengue fever risk areas in Nepal. Here, we used reported dengue cases and a set of bioclimatic variables on the MaxEnt ecological niche modeling approach to model the climatic niche and map present and future (2050s and 2070s) climatically suitable areas under different representative concentration pathways (RCP2.6, RCP6.0 and RCP8.5). Simulation-based estimates suggest that climatically suitable areas for dengue fever are presently distributed throughout the lowland Tarai from east to west and in river valleys at lower elevations. Under the different climate change scenarios, these areas will be slightly shifted towards higher elevation with varied magnitude and spatial patterns. Population exposed to climatically suitable areas of dengue fever in Nepal is anticipated to further increase in both 2050s and 2070s on all the assumed emission scenarios. These findings could be instrumental to plan and execute the strategic interventions for controlling dengue fever in Nepal. PMID:29360797

  15. Sodium Velocity Maps on Mercury

    NASA Technical Reports Server (NTRS)

    Potter, A. E.; Killen, R. M.

    2011-01-01

    The objective of the current work was to measure two-dimensional maps of sodium velocities on the Mercury surface and examine the maps for evidence of sources or sinks of sodium on the surface. The McMath-Pierce Solar Telescope and the Stellar Spectrograph were used to measure Mercury spectra that were sampled at 7 milliAngstrom intervals. Observations were made each day during the period October 5-9, 2010. The dawn terminator was in view during that time. The velocity shift of the centroid of the Mercury emission line was measured relative to the solar sodium Fraunhofer line corrected for radial velocity of the Earth. The difference between the observed and calculated velocity shift was taken to be the velocity vector of the sodium relative to Earth. For each position of the spectrograph slit, a line of velocities across the planet was measured. Then, the spectrograph slit was stepped over the surface of Mercury at 1 arc second intervals. The position of Mercury was stabilized by an adaptive optics system. The collection of lines were assembled into an images of surface reflection, sodium emission intensities, and Earthward velocities over the surface of Mercury. The velocity map shows patches of higher velocity in the southern hemisphere, suggesting the existence of sodium sources there. The peak earthward velocity occurs in the equatorial region, and extends to the terminator. Since this was a dawn terminator, this might be an indication of dawn evaporation of sodium. Leblanc et al. (2008) have published a velocity map that is similar.

  16. Visualising crystal packing interactions in solid-state NMR: Concepts and applications

    NASA Astrophysics Data System (ADS)

    Zilka, Miri; Sturniolo, Simone; Brown, Steven P.; Yates, Jonathan R.

    2017-10-01

    In this article, we introduce and apply a methodology, based on density functional theory and the gauge-including projector augmented wave approach, to explore the effects of packing interactions on solid-state nuclear magnetic resonance (NMR) parameters. A visual map derived from a so-termed "magnetic shielding contribution field" can be made of the contributions to the magnetic shielding of a specific site—partitioning the chemical shift to specific interactions. The relation to the established approaches of examining the molecule to crystal change in the chemical shift and the nuclear independent chemical shift is established. The results are applied to a large sample of 71 molecular crystals and three further specific examples from supermolecular chemistry and pharmaceuticals. This approach extends the NMR crystallography toolkit and provides insight into the development of both cluster based approaches to the predictions of chemical shifts and for empirical predictions of chemical shifts in solids.

  17. Measuring (19)F shift anisotropies and (1)H-(19)F dipolar interactions with ultrafast MAS NMR.

    PubMed

    Martini, Francesca; Miah, Habeeba K; Iuga, Dinu; Geppi, Marco; Titman, Jeremy J

    2015-10-01

    A new (19)F anisotropic-isotropic shift correlation experiment is described that operates with ultrafast MAS, resulting in good resolution of isotropic (19)F shifts in the detection dimension. The new experiment makes use of a recoupling sequence designed using symmetry principles that reintroduces the (19)F chemical shift anisotropy in the indirect dimension. The situations in which the new experiment is appropriate are discussed, and the (19)F shift anisotropy parameters in poly(difluoroethylene) (PVDF) are measured. In addition, similar recoupling sequences are shown to be effective for measuring (1)H-(19)F distances via the heteronuclear dipolar interaction. This is demonstrated by application to a recently synthesized zirconium phosphonate material that contains one-dimensional chains linked by H-F hydrogen bonds. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Mapping mutational effects along the evolutionary landscape of HIV envelope.

    PubMed

    Haddox, Hugh K; Dingens, Adam S; Hilton, Sarah K; Overbaugh, Julie; Bloom, Jesse D

    2018-03-28

    The immediate evolutionary space accessible to HIV is largely determined by how single amino acid mutations affect fitness. These mutational effects can shift as the virus evolves. However, the prevalence of such shifts in mutational effects remains unclear. Here, we quantify the effects on viral growth of all amino acid mutations to two HIV envelope (Env) proteins that differ at [Formula: see text]100 residues. Most mutations similarly affect both Envs, but the amino acid preferences of a minority of sites have clearly shifted. These shifted sites usually prefer a specific amino acid in one Env, but tolerate many amino acids in the other. Surprisingly, shifts are only slightly enriched at sites that have substituted between the Envs-and many occur at residues that do not even contact substitutions. Therefore, long-range epistasis can unpredictably shift Env's mutational tolerance during HIV evolution, although the amino acid preferences of most sites are conserved between moderately diverged viral strains. © 2018, Haddox et al.

  19. Evaluating the traditional day and night shift in an acute care surgery fellowship: Is the swing shift a better choice?

    PubMed

    Chestovich, Paul J; McNicoll, Christopher F; Ingalls, Nichole K; Kuhls, Deborah A; Fraser, Douglas R; Morrissey, Shawna L; Fildes, John J

    2018-01-01

    Fellowship trainees in acute care surgery require experience in the management of complex and operative trauma cases. Trauma center staffing usually follows standard 12-hour or 24-hour shifts, with resident and fellow trainees following a similar schedule. Although trauma admissions can be generally unpredictable, we analyzed temporal trends of trauma patient arrival times to determine the best time frame to maximize trainee experience during each day. We reviewed 10 years (2007-2016) of trauma registry data for blunt and penetrating trauma activations. Hourly volumetric trends were observed, and three specific events were chosen for detailed analysis: (1) trauma activation with Injury Severity Score (ISS) greater than 15, (2) laparotomy for trauma, and (3) thoracotomy for trauma. A retrospective shift log was created, which included day (7:00 AM to 7:00 PM), night (7:00 PM to 7:00 AM), and swing (noon to midnight) shifts. A swing shift was chosen because it captures the peak volume for all three events. Means and 95% confidence intervals were calculated, and comparisons were made between shifts using the Wilcoxon matched-pairs signed rank test with Bonferroni correction, and p less than 0.05 considered significant. During the 10-year study period, 28,287 patients were treated at our trauma center. This included the evaluation and management of 7,874 patients with ISS greater than 15, performance of 1,766 laparotomies, and 392 thoracotomies for trauma. Swing shift was superior to both day and night shifts for ISS greater than 15 (p < 0.001). Both swing and night shifts were superior to day shift for laparotomies (p < 0.001). Swing shift was superior to both day shift (p < 0.001) and night shift (p = 0.031). Shifts with the highest yield of ISS greater than 15, laparotomies, and thoracotomies include night and swing shifts on Fridays and Saturdays. Projected experience of acute care surgery fellows in managing complex trauma patients increases with the integration of swing shifts into the schedule. Daily trauma volume follows a temporal pattern which, when used correctly, can increase trainee exposure to complex and operative trauma cases. We encourage other centers to analyze their volume and adjust trainee schedules accordingly to maximize their educational experience. Therapeutic study, level IV.

  20. Mapping the transcription start points of the Staphylococcus aureus eap, emp, and vwb promoters reveals a conserved octanucleotide sequence that is essential for expression of these genes.

    PubMed

    Harraghy, Niamh; Homerova, Dagmar; Herrmann, Mathias; Kormanec, Jan

    2008-01-01

    Mapping the transcription start points of the eap, emp, and vwb promoters revealed a conserved octanucleotide sequence (COS). Deleting this sequence abolished the expression of eap, emp, and vwb. However, electrophoretic mobility shift assays gave no evidence that this sequence was a binding site for SarA or SaeR, known regulators of eap and emp.

  1. Young Children's Spontaneous Use of Geometry in Maps

    ERIC Educational Resources Information Center

    Shusterman, Anna; Lee, Sang Ah; Spelke, Elizabeth S.

    2008-01-01

    Two experiments tested whether 4-year-old children extract and use geometric information in simple maps without task instruction or feedback. Children saw maps depicting an arrangement of three containers and were asked to place an object into a container designated on the map. In Experiment 1, one of the three locations on the map and the array…

  2. Crosstalk Cancellation for a Simultaneous Phase Shifting Interferometer

    NASA Technical Reports Server (NTRS)

    Olczak, Eugene (Inventor)

    2014-01-01

    A method of minimizing fringe print-through in a phase-shifting interferometer, includes the steps of: (a) determining multiple transfer functions of pixels in the phase-shifting interferometer; (b) computing a crosstalk term for each transfer function; and (c) displaying, to a user, a phase-difference map using the crosstalk terms computed in step (b). Determining a transfer function in step (a) includes measuring intensities of a reference beam and a test beam at the pixels, and measuring an optical path difference between the reference beam and the test beam at the pixels. Computing crosstalk terms in step (b) includes computing an N-dimensional vector, where N corresponds to the number of transfer functions, and the N-dimensional vector is obtained by minimizing a variance of a modulation function in phase shifted images.

  3. Reliable Radiation Hybrid Maps: An Efficient Scalable Clustering-based Approach

    USDA-ARS?s Scientific Manuscript database

    The process of mapping markers from radiation hybrid mapping (RHM) experiments is equivalent to the traveling salesman problem and, thereby, has combinatorial complexity. As an additional problem, experiments typically result in some unreliable markers that reduce the overall quality of the map. We ...

  4. Characterization of local motions in proteins detected by nuclear magnetic resonance relaxation studies

    NASA Astrophysics Data System (ADS)

    Fischer, Mark William Frederick

    1998-08-01

    The study of protein structure and function is incomplete without an understanding of protein dynamics. We use nuclear magnetic resonance (NMR) relaxation studies to probe pico and nano second dynamics in E. coli flavodoxin, measuring both 15N and 13C/sp/prime relaxation. Observing poor correlation between the generalized order parameters, S2, for the N-NH and C'-Cα vectors in this nearly spherical molecule, we conclude that local or semi-local anisotropic motions are present. A new experiment is introduced from which the cross correlation, Rcc, between the carbonyl chemical shift anisotropy relaxation and the C'- Cα dipole-dipole relaxation is obtained. Theoretical modeling of the behavior of S2 N- NH,/ S2C/sp/prime-C/sb[α], and Rcc under specific anisotropic motions allows the construction of motional restriction maps. Analyzing our experimental data in terms of these motional maps allows for the identification of local motions which might otherwise have gone undetected and, more importantly, allows for the nature of the motions to be characterized. This is demonstrated for several helices of flavodoxin which appear to be executing concerted limited rotations about their helical axes.

  5. Adaptive Neuromorphic Circuit for Stereoscopic Disparity Using Ocular Dominance Map

    PubMed Central

    Sharma, Sheena; Gupta, Priti; Markan, C. M.

    2016-01-01

    Stereopsis or depth perception is a critical aspect of information processing in the brain and is computed from the positional shift or disparity between the images seen by the two eyes. Various algorithms and their hardware implementation that compute disparity in real time have been proposed; however, most of them compute disparity through complex mathematical calculations that are difficult to realize in hardware and are biologically unrealistic. The brain presumably uses simpler methods to extract depth information from the environment and hence newer methodologies that could perform stereopsis with brain like elegance need to be explored. This paper proposes an innovative aVLSI design that leverages the columnar organization of ocular dominance in the brain and uses time-staggered Winner Take All (ts-WTA) to adaptively create disparity tuned cells. Physiological findings support the presence of disparity cells in the visual cortex and show that these cells surface as a result of binocular stimulation received after birth. Therefore, creating in hardware cells that can learn different disparities with experience not only is novel but also is biologically more realistic. These disparity cells, when allowed to interact diffusively on a larger scale, can be used to adaptively create stable topological disparity maps in silicon. PMID:27243029

  6. Evaluation of protein adsorption and preferred binding regions in multimodal chromatography using NMR

    PubMed Central

    Chung, Wai Keen; Freed, Alexander S.; Holstein, Melissa A.; McCallum, Scott A.; Cramer, Steven M.

    2010-01-01

    NMR titration experiments with labeled human ubiquitin were employed in concert with chromatographic data obtained with a library of ubiquitin mutants to study the nature of protein adsorption in multimodal (MM) chromatography. The elution order of the mutants on the MM resin was significantly different from that obtained by ion-exchange chromatography. Further, the chromatographic results with the protein library indicated that mutations in a defined region induced greater changes in protein affinity to the solid support. Chemical shift mapping and determination of dissociation constants from NMR titration experiments with the MM ligand and isotopically enriched ubiquitin were used to determine and rank the relative binding affinities of interaction sites on the protein surface. The results with NMR confirmed that the protein possessed a distinct preferred binding region for the MM ligand in agreement with the chromatographic results. Finally, coarse-grained ligand docking simulations were employed to study the modes of interaction between the MM ligand and ubiquitin. The use of NMR titration experiments in concert with chromatographic data obtained with protein libraries represents a previously undescribed approach for elucidating the structural basis of protein binding affinity in MM chromatographic systems. PMID:20837551

  7. Concept Mapping Improves Metacomprehension Accuracy among 7th Graders

    ERIC Educational Resources Information Center

    Redford, Joshua S.; Thiede, Keith W.; Wiley, Jennifer; Griffin, Thomas D.

    2012-01-01

    Two experiments explored concept map construction as a useful intervention to improve metacomprehension accuracy among 7th grade students. In the first experiment, metacomprehension was marginally better for a concept mapping group than for a rereading group. In the second experiment, metacomprehension accuracy was significantly greater for a…

  8. The temporal advantage for individuating objects of expertise: perceptual expertise is an early riser.

    PubMed

    Curby, Kim M; Gauthier, Isabel

    2009-06-10

    The identification of faces has a temporal advantage over that of other object categories. The orientation-specific nature of this advantage suggests that it stems from our extensive experience and resulting expertise with upright faces. While experts can identify objects faster than novices, it is unclear exactly how the temporal dynamics of identification are changed by expertise and whether the nature of this temporal advantage is similar for face and non-face objects of expertise. Here, we titrated encoding time using a backward-masking paradigm with variable stimulus-mask onset-asynchronies and mapped the resulting effect on recognition for upright and inverted faces (Experiment 1) and for cars among car experts and car novices (Experiment 2). Performance for upright faces and cars among car experts rose above chance between 33 and 70 ms before that for inverted faces or cars among car novices. A shifted exponential function fitted to these data suggested that performance started to rise earlier for experts than for novices, but that additional encoding time increased performance at a similar rate. Experience influences the availability of information early in processing, possibly through the recruitment of more category-selective neurons, while the rate of perceptual processing may be less flexible and limited by inherent physiological constraints.

  9. The QMAP and MAT/TOCO Experiments for Measuring Anisotropy in the Cosmic Microwave Background

    NASA Astrophysics Data System (ADS)

    Miller, A.; Beach, J.; Bradley, S.; Caldwell, R.; Chapman, H.; Devlin, M. J.; Dorwart, W. B.; Herbig, T.; Jones, D.; Monnelly, G.; Netterfield, C. B.; Nolta, M.; Page, L. A.; Puchalla, J.; Robertson, T.; Torbet, E.; Tran, H. T.; Vinje, W. E.

    2002-06-01

    We describe two related experiments that measured the anisotropy in the cosmic microwave background (CMB). QMAP was a balloon-borne telescope that flew twice in 1996, collecting data on degree angular scales with an array of six high electron mobility transistor-based amplifiers (HEMTs). QMAP used an interlocking scan strategy to directly produce high signal-to-noise ratio CMB maps over a limited region of sky. The QMAP gondola was then refitted for ground-based work as the MAT/TOCO experiment. Observations were made from 5200 m on Cerro Toco in Northern Chile in 1997 and 1998 using time domain beam synthesis. MAT/TOCO measured the rise and fall of the CMB angular spectrum, thereby localizing the position of the first peak to lpeak=216+/-14. In addition to describing the instruments, we discuss the data selection methods, check for systematic errors, and compare the MAT/TOCO results to those from recent experiments. The previously reported data are updated to account for a small calibration shift and corrected to account for a small contribution from known sources of foreground emission. The resulting amplitude of the first peak for 160

  10. The Girls on Ice program: Improving perceptions of climate change and environmental stewardship by exploring a glacier landscape

    NASA Astrophysics Data System (ADS)

    Young, J. C.; Conner, L.; Pettit, E. C.

    2017-12-01

    Girls on Ice is a unique, free, science and mountaineering experience for underserved girls aged 16 to 18. Each year, two teams of nine girls spend eight days on a remote Alaska or Washington glacier to learn about glaciology, climate change, and alpine ecology (as well as mountaineering, art and leadership). During the program, the girls live on, explore and study a glacier and the visibly climate change-altered landscape that surrounds it, through both instructor-led modules and scientific field studies the girls design themselves. Time spent on the glacier means witnessing rivers of meltwater running off the surface, climbing 300 m uphill to where the glacier last sat 150 years ago, and learning how scientists monitor the glacier's retreat. Previous studies have shown that pro-environmental behavior in youth is strongly influenced by having significant life experiences outdoors, and that engagement of citizens in a climate change-impacted landscape is emerging as a powerful way to connect people to environment and to motivate environmental action. Given the significant life experience provided by our unique wilderness format, and the interactions with a rapidly changing glacier landscape, this study examines how participation in Girls on Ice impacts the 16 to 18 year-old participants' perceptions of climate change, as well as their sense of environmental identity. We use mixed qualitative and quantitative methods, including pre- and post-program questionnaires, an in-program focus group discussion, end-of-program interviews, and early and late in-program concept (node-link) mapping exercises. Preliminary results from qualitative data show a shift in many girls' perceptions of climate change towards being motivated to act to combat it, with particular reference to glaciers as a key component prompting that shift. Ultimately, this study aims to demonstrate the value of tenets of environmental and outdoor education theory, namely significant life experiences and interactions with climate change-impacted landscapes, for motivating greater climate change awareness and mitigation behavior in youth.

  11. 20th century Betula pubescens subsp. czerepanovii tree- and forest lines in Norway.

    PubMed

    Bryn, Anders; Potthoff, Kerstin

    2017-01-01

    Georeferenced tree- and forest line data has a wide range of applications and are increasingly used for e.g. monitoring of climate change impacts and range shift modelling. As part of a research project, registrations of previously re-mapped tree- and forest lines have been georeferenced. The data described in this paper contains 100 re-mapped registrations of Betula pubescens subsp. czerepanovii throughout Norway. All of the re-mapped tree- and forest line localities are georeferenced, elevation and aspect are given, elevational and spatial uncertainty are provided, and the re-mapping methods are explained. The published data weremapped for the first time between 1819 and 1963. The same sites were re-mapped between 1928 and 1996, but have until now been missing spatial coordinates. The entries contain 40 x 2 tree lines and 60 x 2 forest lines, most likely presenting the regionally highest registered tree- and forest lines at the given time. The entire material is stored and available for download through the GBIF server. Previously, the entries have been published in journals or reports, partly in Norwegian or German only. Without the provision of the spatial coordinates, the specific locations have been unknown. The material is now available for modelling and monitoring of tree- and forest line range shifts: The recordings are useful for interpretation of climate change impacts on tree- and forest lines, and the locations of re-mapped tree- and forest lines can be implemented in future monitoring projects. Since the recordings most likely provide the highest registered Betula pubescens subsp. czerepanovii locations within their specific regions, they are probably representing the contemporary physiognomic range limits.

  12. Analogical processes in children's understanding of spatial representations.

    PubMed

    Yuan, Lei; Uttal, David; Gentner, Dedre

    2017-06-01

    We propose that map reading can be construed as a form of analogical mapping. We tested 2 predictions that follow from this claim: First, young children's patterns of performance in map reading tasks should parallel those found in analogical mapping tasks; and, second, children will benefit from guided alignment instructions that help them see the relational correspondences between the map and the space. In 4 experiments, 3-year-olds completed a map reading task in which they were asked to find hidden objects in a miniature room, using a corresponding map. We manipulated the availability of guided alignment (showing children the analogical mapping between maps and spaces; Experiments 1, 2, and 3a), the format of guided alignment (gesture or relational language; Experiment 2), and the iconicity of maps (Experiments 3a and 3b). We found that (a) young children's difficulties in map reading follow from known patterns of analogical development-for example, focusing on object similarity over relational similarity; and (b) guided alignment based on analogical reasoning led to substantially better performance. Results also indicated that children's map reading performance was affected by the format of guided alignment, the iconicity of the maps, and the order of tasks. The results bear on the developmental mechanisms underlying young children's learning of spatial representations and also suggest ways to support this learning. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Arctic Sea Ice Classification and Mapping for Surface Albedo Parameterization in Sea Ice Modeling

    NASA Astrophysics Data System (ADS)

    Nghiem, S. V.; Clemente-Colón, P.; Perovich, D. K.; Polashenski, C.; Simpson, W. R.; Rigor, I. G.; Woods, J. E.; Nguyen, D. T.; Neumann, G.

    2016-12-01

    A regime shift of Arctic sea ice from predominantly perennial sea ice (multi-year ice or MYI) to seasonal sea ice (first-year ice or FYI) has occurred in recent decades. This shift has profoundly altered the proportional composition of different sea ice classes and the surface albedo distribution pertaining to each sea ice class. Such changes impacts physical, chemical, and biological processes in the Arctic atmosphere-ice-ocean system. The drastic changes upset the traditional geophysical representation of surface albedo of the Arctic sea ice cover in current models. A critical science issue is that these profound changes must be rigorously and systematically observed and characterized to enable a transformative re-parameterization of key model inputs, such as ice surface albedo, to ice-ocean-atmosphere climate modeling in order to obtain re-analyses that accurately reproduce Arctic changes and also to improve sea ice and weather forecast models. Addressing this challenge is a strategy identified by the National Research Council study on "Seasonal to Decadal Predictions of Arctic Sea Ice - Challenges and Strategies" to replicate the new Arctic reality. We review results of albedo characteristics associated with different sea ice classes such as FYI and MYI. Then we demonstrate the capability for sea ice classification and mapping using algorithms developed by the Jet Propulsion Laboratory and by the U.S. National Ice Center for use with multi-sourced satellite radar data at L, C, and Ku bands. Results obtained with independent algorithms for different radar frequencies consistently identify sea ice classes and thereby cross-verify the sea ice classification methods. Moreover, field observations obtained from buoy webcams and along an extensive trek across Elson Lagoon and a sector of the Beaufort Sea during the BRomine, Ozone, and Mercury EXperiment (BROMEX) in March 2012 are used to validate satellite products of sea ice classes. This research enables the mapping of Arctic sea ice classes over multiple decades using multiple satellite radar datasets with both coarse resolution for synoptic scales and high resolution for local and regional scales, which are crucial for realistic surface albedo parameterization to significantly advance sea ice forecast and projection models.

  14. Triple Resonance Solid State NMR Experiments with Reduced Dimensionality Evolution Periods

    NASA Astrophysics Data System (ADS)

    Astrof, Nathan S.; Lyon, Charles E.; Griffin, Robert G.

    2001-10-01

    Two solid state NMR triple resonance experiments which utilize the simultaneous incrementation of two chemical shift evolution periods to obtain a spectrum with reduced dimensionality are described. The CON CA experiment establishes the correlation of 13Ci-1 to 13Cαi and 15Ni by simultaneously encoding the 13COi-1 and 15Ni chemical shifts. The CAN COCA experiment establishes the correlation 13Cai and 15COi to 13Cαi-1 and 15Ni-1 within a single experiment by simultaneous encoding of the 13Cαi and 15Ni chemical shifts. This experiment establishes sequential amino acid correlations in close analogy to the solution state HNCA experiment. Reduced dimensionality 2D experiments are a practical alternative to recording multiple 3D data sets for the purpose of obtaining sequence-specific resonance assignments of peptides and proteins in the solid state.

  15. Linguistic attention control: attention shifting governed by grammaticized elements of language.

    PubMed

    Taube-Schiff, Marlene; Segalowitz, Norman

    2005-05-01

    In 2 experiments, the authors investigated attention control for tasks involving the processing of grammaticized linguistic stimuli (function words) contextualized in sentence fragments. Attention control was operationalized as shift costs obtained with adult speakers of English in an alternating-runs experimental design (R. D. Rogers & S. Monsell, 1995). Experiment 1 yielded significant attention shift costs between tasks involving judgments about the meanings of grammatical function words. The authors used a 3-stage experimental design (G. Wylie & A. Allport, 2000), and the emerging pattern of results implicated task set reconfiguration and not task set inertia in these shift costs. Experiment 2 further demonstrated that shift costs were lower when the tasks involved shared attentional resources (processing the same grammatical dimension) versus unshared resources (different grammatical dimensions). The authors discuss the results from a cognitive linguistic perspective and for their implications for the view that language itself can serve a special attention-directing function.

  16. Shifting from Production to Service to Experience-Based Operations

    NASA Astrophysics Data System (ADS)

    Angelis, Jannis; de Lima, Edson Pinheiro

    This chapter covers the shift in focus of value added business operations from ­production to services, and in turn, to experience-based operations where customer involvement itself becomes part of the offering. The shift has significant implications for how businesses are managed. The greater service focus affects the firm's unique value proposition, which necessitates considerations on strategy, supplier relations, post-sale offerings and so on. Meanwhile, the inclusion of customer ­experiences affect the way operations are designed and employed so that these are structurally systematically captured and capitalised.

  17. Enhanced NMR Discrimination of Pharmaceutically Relevant Molecular Crystal Forms through Fragment-Based Ab Initio Chemical Shift Predictions.

    PubMed

    Hartman, Joshua D; Day, Graeme M; Beran, Gregory J O

    2016-11-02

    Chemical shift prediction plays an important role in the determination or validation of crystal structures with solid-state nuclear magnetic resonance (NMR) spectroscopy. One of the fundamental theoretical challenges lies in discriminating variations in chemical shifts resulting from different crystallographic environments. Fragment-based electronic structure methods provide an alternative to the widely used plane wave gauge-including projector augmented wave (GIPAW) density functional technique for chemical shift prediction. Fragment methods allow hybrid density functionals to be employed routinely in chemical shift prediction, and we have recently demonstrated appreciable improvements in the accuracy of the predicted shifts when using the hybrid PBE0 functional instead of generalized gradient approximation (GGA) functionals like PBE. Here, we investigate the solid-state 13 C and 15 N NMR spectra for multiple crystal forms of acetaminophen, phenobarbital, and testosterone. We demonstrate that the use of the hybrid density functional instead of a GGA provides both higher accuracy in the chemical shifts and increased discrimination among the different crystallographic environments. Finally, these results also provide compelling evidence for the transferability of the linear regression parameters mapping predicted chemical shieldings to chemical shifts that were derived in an earlier study.

  18. Enhanced NMR Discrimination of Pharmaceutically Relevant Molecular Crystal Forms through Fragment-Based Ab Initio Chemical Shift Predictions

    PubMed Central

    2016-01-01

    Chemical shift prediction plays an important role in the determination or validation of crystal structures with solid-state nuclear magnetic resonance (NMR) spectroscopy. One of the fundamental theoretical challenges lies in discriminating variations in chemical shifts resulting from different crystallographic environments. Fragment-based electronic structure methods provide an alternative to the widely used plane wave gauge-including projector augmented wave (GIPAW) density functional technique for chemical shift prediction. Fragment methods allow hybrid density functionals to be employed routinely in chemical shift prediction, and we have recently demonstrated appreciable improvements in the accuracy of the predicted shifts when using the hybrid PBE0 functional instead of generalized gradient approximation (GGA) functionals like PBE. Here, we investigate the solid-state 13C and 15N NMR spectra for multiple crystal forms of acetaminophen, phenobarbital, and testosterone. We demonstrate that the use of the hybrid density functional instead of a GGA provides both higher accuracy in the chemical shifts and increased discrimination among the different crystallographic environments. Finally, these results also provide compelling evidence for the transferability of the linear regression parameters mapping predicted chemical shieldings to chemical shifts that were derived in an earlier study. PMID:27829821

  19. High resolution satellite remote sensing used in a stratified random sampling scheme to quantify the constituent land cover components of the shifting cultivation mosaic of the Democratic Republic of Congo

    NASA Astrophysics Data System (ADS)

    Molinario, G.; Hansen, M.; Potapov, P.

    2016-12-01

    High resolution satellite imagery obtained from the National Geospatial Intelligence Agency through NASA was used to photo-interpret sample areas within the DRC. The area sampled is a stratifcation of the forest cover loss from circa 2014 that either occurred completely within the previosly mapped homogenous area of the Rural Complex, at it's interface with primary forest, or in isolated forest perforations. Previous research resulted in a map of these areas that contextualizes forest loss depending on where it occurs and with what spatial density, leading to a better understading of the real impacts on forest degradation of livelihood shifting cultivation. The stratified random sampling approach of these areas allows the characterization of the constituent land cover types within these areas, and their variability throughout the DRC. Shifting cultivation has a variable forest degradation footprint in the DRC depending on many factors that drive it, but it's role in forest degradation and deforestation had been disputed, leading us to investigate and quantify the clearing and reuse rates within the strata throughout the country.

  20. Computation of Chemical Shifts for Paramagnetic Molecules: A Laboratory Experiment for the Undergraduate Curriculum

    ERIC Educational Resources Information Center

    Pritchard, Benjamin P.; Simpson, Scott; Zurek, Eva; Autschbach, Jochen

    2014-01-01

    A computational experiment investigating the [superscript 1]H and [superscript 13]C nuclear magnetic resonance (NMR) chemical shifts of molecules with unpaired electrons has been developed and implemented. This experiment is appropriate for an upper-level undergraduate laboratory course in computational, physical, or inorganic chemistry. The…

  1. Permanent magnet assembly producing a strong tilted homogeneous magnetic field: towards magic angle field spinning NMR and MRI.

    PubMed

    Sakellariou, Dimitris; Hugon, Cédric; Guiga, Angelo; Aubert, Guy; Cazaux, Sandrine; Hardy, Philippe

    2010-12-01

    We introduce a cylindrical permanent magnet design that generates a homogeneous and strong magnetic field having an arbitrary inclination with respect to the axis of the cylinder. The analytical theory of 3 D magnetostatics has been applied to this problem, and a hybrid magnet structure has been designed. This structure contains two magnets producing a longitudinal and transverse component for the magnetic field, whose amplitudes and homogeneities can be fully controlled by design. A simple prototype has been constructed using inexpensive small cube magnets, and its magnetic field has been mapped using Hall and NMR probe sensors. This magnet can, in principle, be used for magic angle field spinning NMR and MRI experiments allowing for metabolic chemical shift profiling in small living animals. Copyright © 2010 John Wiley & Sons, Ltd.

  2. Frequency shifts in gravitational resonance spectroscopy

    DOE PAGES

    Baeßler, S.; Nesvizhevsky, V. V.; Pignol, G.; ...

    2015-02-25

    Quantum states of ultracold neutrons in a gravitational field are characterized through gravitational resonance spectroscopy. This paper discusses systematic effects that appear in the spectroscopic measurements. The discussed frequency shifts-which we call the Stern-Gerlach shift, interference shift, and spectator-state shift-appear in conceivable measurement schemes and have general importance. Lastly, these shifts have to be taken into account in precision experiments.

  3. Implementing a night-shift clinical nurse specialist.

    PubMed

    Becker, Dawn Marie

    2013-01-01

    Night-shift nurses receive fewer educational opportunities and less administrative support than do day-shift staff, tend to be newer, with less experience and fewer resources, and experience greater turnover rates, stress, and procedural errors. In an attempt to bridge the gap between day- and night-shift nursing, a night-shift clinical nurse specialist (CNS) position was created in a midsized, community teaching hospital. The goal was to provide an advanced practice presence to improve patient outcomes, communication, education, and cost-effectiveness. The night-shift CNS participated in nursing education and skill certifications, communicated new procedures and information, and created a communication committee specifically for night-shift nurses. Through regular rounding and on-call notification, the CNS was available to every area of the hospital for consultation and clinical assistance and assisted with rapid responses, codes, and traumas. Providing education during night shift reduced overtime costs and increased morale, positively affecting turnover rates. The night-shift CNS position has improved morale and equalized support for night-shift nurses. More research, most notably in specific night-shift metrics, is necessary, and with the implementation of the role in additional facilities, more can be understood about improving patient care and nursing staff satisfaction during night shift.

  4. Phase correction, phase resetting, and phase shifts after subliminal timing perturbations in sensorimotor synchronization.

    PubMed

    Repp, B H

    2001-06-01

    Recent studies of synchronized finger tapping have shown that perceptually subliminal phase shifts in an auditory sequence are rapidly compensated for in the motor activity (B. H. Repp, 2000a). Experiment 1 used a continuation-tapping task to confirm that this compensation is indeed a phase correction, not an adjustment of the central timekeeper period. Experiments 2-5 revealed that this phase correction occurs even when there is no ordinary sensorimotor asynchrony--when the finger taps are in antiphase or arbitrary phase relative to the auditory sequence (Experiments 2 and 3) or when the tap coinciding with the sequence phase shift is withheld (Experiments 4 and 5). The phase correction observed in the latter conditions was instantaneous, which suggests that phase resetting occurs when the motor activity is discontinuous. A prolonged phase shift suggestive of overcompensation was observed in some conditions, which poses a challenge to pure phase correction models.

  5. Random sequences generation through optical measurements by phase-shifting interferometry

    NASA Astrophysics Data System (ADS)

    François, M.; Grosges, T.; Barchiesi, D.; Erra, R.; Cornet, A.

    2012-04-01

    The development of new techniques for producing random sequences with a high level of security is a challenging topic of research in modern cryptographics. The proposed method is based on the measurement by phase-shifting interferometry of the speckle signals of the interaction between light and structures. We show how the combination of amplitude and phase distributions (maps) under a numerical process can produce random sequences. The produced sequences satisfy all the statistical requirements of randomness and can be used in cryptographic schemes.

  6. Confocal shift interferometry of coherent emission from trapped dipolar excitons

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Repp, J.; Nanosystems Initiative Munich; Center for NanoScience and Fakultät für Physik, Ludwig-Maximilians-Universität, Geschwister-Scholl-Platz 1, 80539 München

    2014-12-15

    We introduce a confocal shift-interferometer based on optical fibers. The presented spectroscopy allows measuring coherence maps of luminescent samples with a high spatial resolution even at cryogenic temperatures. We apply the spectroscopy onto electrostatically trapped, dipolar excitons in a semiconductor double quantum well. We find that the measured spatial coherence length of the excitonic emission coincides with the point spread function of the confocal setup. The results are consistent with a temporal coherence of the excitonic emission down to temperatures of 250 mK.

  7. Observation and correction of transient cavitation-induced PRFS thermometry artifacts during radiofrequency ablation, using simultaneous ultrasound/MR imaging.

    PubMed

    Viallon, Magalie; Terraz, Sylvain; Roland, Joerg; Dumont, Erik; Becker, Christoph D; Salomir, Rares

    2010-04-01

    MR thermometry based on the proton resonance frequency shift (PRFS) is the most commonly used method for the monitoring of thermal therapies. As the chemical shift of water protons is temperature dependent, the local temperature variation (relative to an initial baseline) may be calculated from time-dependent phase changes in gradient-echo (GRE) MR images. Dynamic phase shift in GRE images is also produced by time-dependent changes in the magnetic bulk susceptibility of tissue. Gas bubbles (known as "white cavitation") are frequently visualized near the RF electrode in ultrasonography-guided radio frequency ablation (RFA). This study aimed to investigate RFA-induced cavitation's effects by using simultaneous ultrasonography and MRI, to both visualize the cavitation and quantify the subsequent magnetic susceptibility-mediated errors in concurrent PRFS MR-thermometry (MRT) as well as to propose a first-order correction for the latter errors. RF heating in saline gels and in ex vivo tissues was performed with MR-compatible bipolar and monopolar electrodes inside a 1.5 T MR clinical scanner. Ultrasonography simultaneous to PRFS MRT was achieved using a MR-compatible phased-array ultrasonic transducer. PRFS MRT was performed interleaved in three orthogonal planes and compared to measurements from fluoroptic sensors, under low and, respectively, high RFA power levels. Control experiments were performed to isolate the main source of errors in standard PRFS thermometry. Ultrasonography, MRI and digital camera pictures clearly demonstrated generation of bubbles every time when operating the radio frequency equipment at therapeutic powers (> or = 30 W). Simultaneous bimodal (ultrasonography and MRI) monitoring of high power RF heating demonstrated a correlation between the onset of the PRFS-thermometry errors and the appearance of bubbles around the applicator. In an ex vivo study using a bipolar RF electrode under low power level (5 W), the MR measured temperature curves accurately matched the reference fluoroptic data. In similar ex vivo studies when applying higher RFA power levels (30 W), the correlation plots of MR thermometry versus fluoroptic data showed large errors in PRFS-derived temperature (up to 45 degrees C absolute deviation, positive or negative) depending not only on fluoroptic tip position but also on the RF electrode orientation relative to the B0 axis. Regions with apparent decrease in the PRFS-derived temperature maps as much as 30 degrees C below the initial baseline were visualized during RFA high power application. Ex vivo data were corrected assuming a Gaussian dynamic source of susceptibility, centered in the anode/cathode gap of the RF bipolar electrode. After correction, the temperature maps recovered the revolution symmetry pattern predicted by theory and matched the fluoroptic data within 4.5 degrees C mean offset. RFA induces dynamic changes in magnetic bulk susceptibility in biological tissue, resulting in large and spatially dependent errors of phase-subtraction-only PRFS MRT and unexploitable thermal dose maps. These thermometry artifacts were strongly correlated with the appearance of transient cavitation. A first-order dynamic model of susceptibility provided a useful method for minimizing these artifacts in phantom and ex vivo experiments.

  8. An Innovative Method of Teaching-Learning Strategy to Enhance the Learner's Educational Process: Paradigm Shift from Conventional Approach to Modern Approach by Neurocognitive Based Concept Mapping

    ERIC Educational Resources Information Center

    Ramachandran, Sridhar; Pandia Vadivu, P.

    2014-01-01

    This study examines the effectiveness of Neurocognitive Based Concept Mapping (NBCM) on students' learning in a science course. A total of 32 grade IX of high school Central Board of Secondary Education (CBSE) students were involved in this study by pre-test and post-test measurements. They were divided into two groups: NBCM group as an…

  9. Image Mining in Remote Sensing for Coastal Wetlands Mapping: from Pixel Based to Object Based Approach

    NASA Astrophysics Data System (ADS)

    Farda, N. M.; Danoedoro, P.; Hartono; Harjoko, A.

    2016-11-01

    The availably of remote sensing image data is numerous now, and with a large amount of data it makes “knowledge gap” in extraction of selected information, especially coastal wetlands. Coastal wetlands provide ecosystem services essential to people and the environment. The aim of this research is to extract coastal wetlands information from satellite data using pixel based and object based image mining approach. Landsat MSS, Landsat 5 TM, Landsat 7 ETM+, and Landsat 8 OLI images located in Segara Anakan lagoon are selected to represent data at various multi temporal images. The input for image mining are visible and near infrared bands, PCA band, invers PCA bands, mean shift segmentation bands, bare soil index, vegetation index, wetness index, elevation from SRTM and ASTER GDEM, and GLCM (Harralick) or variability texture. There is three methods were applied to extract coastal wetlands using image mining: pixel based - Decision Tree C4.5, pixel based - Back Propagation Neural Network, and object based - Mean Shift segmentation and Decision Tree C4.5. The results show that remote sensing image mining can be used to map coastal wetlands ecosystem. Decision Tree C4.5 can be mapped with highest accuracy (0.75 overall kappa). The availability of remote sensing image mining for mapping coastal wetlands is very important to provide better understanding about their spatiotemporal coastal wetlands dynamics distribution.

  10. Velocity navigator for motion compensated thermometry.

    PubMed

    Maier, Florian; Krafft, Axel J; Yung, Joshua P; Stafford, R Jason; Elliott, Andrew; Dillmann, Rüdiger; Semmler, Wolfhard; Bock, Michael

    2012-02-01

    Proton resonance frequency shift thermometry is sensitive to breathing motion that leads to incorrect phase differences. In this work, a novel velocity-sensitive navigator technique for triggering MR thermometry image acquisition is presented. A segmented echo planar imaging pulse sequence was modified for velocity-triggered temperature mapping. Trigger events were generated when the estimated velocity value was less than 0.2 cm/s during the slowdown phase in parallel to the velocity-encoding direction. To remove remaining high-frequency spikes from pulsation in real time, a Kalman filter was applied to the velocity navigator data. A phantom experiment with heating and an initial volunteer experiment without heating were performed to show the applicability of this technique. Additionally, a breath-hold experiment was conducted for comparison. A temperature rise of ΔT = +37.3°C was seen in the phantom experiment, and a root mean square error (RMSE) outside the heated region of 2.3°C could be obtained for periodic motion. In the volunteer experiment, a RMSE of 2.7°C/2.9°C (triggered vs. breath hold) was measured. A novel velocity navigator with Kalman filter postprocessing in real time significantly improves the temperature accuracy over non-triggered acquisitions and suggests being comparable to a breath-held acquisition. The proposed technique might be clinically applied for monitoring of thermal ablations in abdominal organs.

  11. Ultrafast modulation of the plasma frequency of vertically aligned indium tin oxide rods.

    PubMed

    Tice, Daniel B; Li, Shi-Qiang; Tagliazucchi, Mario; Buchholz, D Bruce; Weiss, Emily A; Chang, Robert P H

    2014-03-12

    Light-matter interaction at the nanoscale is of particular interest for future photonic integrated circuits and devices with applications ranging from communication to sensing and imaging. In this Letter a combination of transient absorption (TA) and the use of third harmonic generation as a probe (THG-probe) has been adopted to investigate the response of the localized surface plasmon resonances (LSPRs) of vertically aligned indium tin oxide rods (ITORs) upon ultraviolet light (UV) excitation. TA experiments, which are sensitive to the extinction of the LSPR, show a fluence-dependent increase in the frequency and intensity of the LSPR. The THG-probe experiments show a fluence-dependent decrease of the LSPR-enhanced local electric field intensity within the rod, consistent with a shift of the LSPR to higher frequency. The kinetics from both TA and THG-probe experiments are found to be independent of the fluence of the pump. These results indicate that UV excitation modulates the plasma frequency of ITO on the ultrafast time scale by the injection of electrons into, and their subsequent decay from, the conduction band of the rods. Increases to the electron concentration in the conduction band of ∼13% were achieved in these experiments. Computer simulation and modeling have been used throughout the investigation to guide the design of the experiments and to map the electric field distribution around the rods for interpreting far-field measurement results.

  12. Journey Mapping the User Experience

    ERIC Educational Resources Information Center

    Samson, Sue; Granath, Kim; Alger, Adrienne

    2017-01-01

    This journey-mapping pilot study was designed to determine whether journey mapping is an effective method to enhance the student experience of using the library by assessing our services from their point of view. Journey mapping plots a process or service to produce a visual representation of a library transaction--from the point at which the…

  13. First experimental demonstration of an isotropic electromagnetic cloak with strict conformal mapping

    PubMed Central

    Ma, Yungui; Liu, Yichao; Lan, Lu; Wu, Tiantian; Jiang, Wei; Ong, C. K.; He, Sailing

    2013-01-01

    In the past years quasi-conformal mapping has been generally used to design broadband electromagnetic cloaks. However, this technique has some inherit practical limitations such as the lateral beam shift, rendering the device visible or difficult to hide a large object. In this work we circumvent these issues by using strict conformal mapping to build the first isotropic cloak. Microwave near-field measurement shows that our device (with dielectric constant larger than unity everywhere) has a very good cloaking performance and a broad frequency response. The present dielectric approach could be technically extended to the fabrication of other conformal devices at higher frequencies. PMID:23851589

  14. Construction and control of a physiological articulatory model

    NASA Astrophysics Data System (ADS)

    Dang, Jianwu; Honda, Kiyoshi

    2004-02-01

    A physiological articulatory model has been constructed using a fast computation method, which replicates midsagittal regions of the speech organs to simulate articulatory movements during speech. This study aims to improve the accuracy of modeling by using the displacement-based finite-element method and to develop a new approach for controlling the model. A ``semicontinuum'' tongue tissue model was realized by a discrete truss structure with continuum viscoelastic cylinders. Contractile effects of the muscles were systemically examined based on model simulations. The results indicated that each muscle drives the tongue toward an equilibrium position (EP) corresponding to the magnitude of the activation forces. The EPs shifted monotonically as the activation force increased. The monotonic shift revealed a unique and invariant mapping, referred to as an EP map, between a spatial position of the articulators and the muscle forces. This study proposes a control method for the articulatory model based on the EP maps, in which co-contractions of agonist and antagonist muscles are taken into account. By utilizing the co-contraction, the tongue tip and tongue dorsum can be controlled to reach their targets independently. Model simulation showed that the co-contraction of agonist and antagonist muscles could increase the stability of a system in dynamic control.

  15. Evolutionary context for the association of γ-globin, serum uric acid, and hypertension in African Americans.

    PubMed

    Shriner, Daniel; Kumkhaek, Chutima; Doumatey, Ayo P; Chen, Guanjie; Bentley, Amy R; Charles, Bashira A; Zhou, Jie; Adeyemo, Adebowale; Rodgers, Griffin P; Rotimi, Charles N

    2015-11-05

    Hyperuricemia and associated cardio-metabolic disorders are more prevalent in African Americans than in European Americans. We used genome-wide admixture mapping and association testing to identify loci with ancestry effects on serum uric acid levels. We analyzed 1,976 African Americans from Washington, D.C, including 1,322 individuals from 328 pedigrees and 654 unrelated individuals, enrolled in the Howard University Family Study. We performed admixture mapping and genome-wide association testing using ~800 k autosomal single-nucleotide polymorphisms (SNPs). We performed fine mapping by dense genotyping. We assessed functionality by a combination of bioinformatic annotation, reporter gene assays, and gel shift experiments. We also analyzed 12,641 individuals enrolled in the National Health and Nutrition Examination Survey. We detected a genome-wide significant locus on chromosome 11p15.4 at which serum uric acid levels increased with increasing African ancestry, independent of kidney function. Fine-mapping identified two independent signals in the β-globin locus. The ancestral allele at SNP rs2855126, located upstream of the hemoglobin, gamma A gene HBG1, was associated with increased serum uric acid levels and higher expression of a reporter gene relative to the derived allele. Hyperuricemia was associated with increased risk of hypertension in 3,767 African Americans (Odds Ratio = 2.48, p = 2.71 × 10(-19)). Given that increased expression of γ-globin leads to increased levels of fetal hemoglobin which confers protection against malaria, we hypothesize that evolution in Africa of protection against malaria may have occurred at the cost of increased serum uric acid levels, contributing to the high rates of hyperuricemia and associated cardio-metabolic disorders observed in African Americans.

  16. Napping during night shift: practices, preferences, and perceptions of critical care and emergency department nurses.

    PubMed

    Fallis, Wendy M; McMillan, Diana E; Edwards, Marie P

    2011-04-01

    Nurses working night shifts are at risk for sleep deprivation, which threatens patient and nurse safety. Little nursing research has addressed napping, an effective strategy to improve performance, reduce fatigue, and increase vigilance. To explore nurses' perceptions, experiences, barriers, and safety issues related to napping/not napping during night shift. A convenience sample of critical care nurses working night shift were interviewed to explore demographics, work schedule and environment, and napping/ not napping experiences, perceptions, and barriers. Transcripts were constantly compared, and categories and themes were identified. Participants were 13 critical care nurses with an average of 17 years' experience. Ten nurses napped regularly; 2 avoided napping because of sleep inertia. The need for and benefits of napping or not during night shift break were linked to patient and nurse safety. Ability to nap was affected by the demands of patient care and safety, staffing needs, and organizational and environmental factors. Nurses identified personal health, safety, and patient care issues supporting the need for a restorative nap during night shift. Barriers to napping exist within the organization/work environment.

  17. Experiments to Distribute Map Generalization Processes

    NASA Astrophysics Data System (ADS)

    Berli, Justin; Touya, Guillaume; Lokhat, Imran; Regnauld, Nicolas

    2018-05-01

    Automatic map generalization requires the use of computationally intensive processes often unable to deal with large datasets. Distributing the generalization process is the only way to make them scalable and usable in practice. But map generalization is a highly contextual process, and the surroundings of a generalized map feature needs to be known to generalize the feature, which is a problem as distribution might partition the dataset and parallelize the processing of each part. This paper proposes experiments to evaluate the past propositions to distribute map generalization, and to identify the main remaining issues. The past propositions to distribute map generalization are first discussed, and then the experiment hypotheses and apparatus are described. The experiments confirmed that regular partitioning was the quickest strategy, but also the less effective in taking context into account. The geographical partitioning, though less effective for now, is quite promising regarding the quality of the results as it better integrates the geographical context.

  18. Attention and Gaze Control in Picture Naming, Word Reading, and Word Categorizing

    ERIC Educational Resources Information Center

    Roelofs, Ardi

    2007-01-01

    The trigger for shifting gaze between stimuli requiring vocal and manual responses was examined. Participants were presented with picture-word stimuli and left- or right-pointing arrows. They vocally named the picture (Experiment 1), read the word (Experiment 2), or categorized the word (Experiment 3) and shifted their gaze to the arrow to…

  19. Shifting Patterns of Agricultural Diversity

    USDA-ARS?s Scientific Manuscript database

    Although monocultural cropping systems can provide the greatest yield efficiency in the short term, more diverse agricultural landscapes may contribute multiple ecosystem benefits. The USDA's Cropland Data Layer provides a yearly map of the agricultural lands of the continental United States broken ...

  20. DISCO: Distance and Spectrum Correlation Optimization Alignment for Two Dimensional Gas Chromatography Time-of-Flight Mass Spectrometry-based Metabolomics

    PubMed Central

    Wang, Bing; Fang, Aiqin; Heim, John; Bogdanov, Bogdan; Pugh, Scott; Libardoni, Mark; Zhang, Xiang

    2010-01-01

    A novel peak alignment algorithm using a distance and spectrum correlation optimization (DISCO) method has been developed for two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC/TOF-MS) based metabolomics. This algorithm uses the output of the instrument control software, ChromaTOF, as its input data. It detects and merges multiple peak entries of the same metabolite into one peak entry in each input peak list. After a z-score transformation of metabolite retention times, DISCO selects landmark peaks from all samples based on both two-dimensional retention times and mass spectrum similarity of fragment ions measured by Pearson’s correlation coefficient. A local linear fitting method is employed in the original two-dimensional retention time space to correct retention time shifts. A progressive retention time map searching method is used to align metabolite peaks in all samples together based on optimization of the Euclidean distance and mass spectrum similarity. The effectiveness of the DISCO algorithm is demonstrated using data sets acquired under different experiment conditions and a spiked-in experiment. PMID:20476746

  1. Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast.

    PubMed

    Chan, C S; Botstein, D

    1993-11-01

    We have developed a colony papillation assay for monitoring the copy number of genetically marked chromosomes II and III in Saccharomyces cerevisiae. The unique feature of this assay is that it allows detection of a gain of the marked chromosomes even if there is a gain of the entire set of chromosomes (increase-in-ploidy). This assay was used to screen for chromosome-gain or increase-in-ploidy mutants. Five complementation groups have been defined for recessive mutations that confer an increase-in-ploidy (ipl) phenotype, which, in each case, cosegregates with a temperature-sensitive growth phenotype. Four new alleles of CDC31, which is required for spindle pole body duplication, were also recovered from this screen. Temperature-shift experiments with ipl1 cells show that they suffer severe nondisjunction at 37 degrees. Similar experiments with ipl2 cells show that they gain entire sets of chromosomes and become arrested as unbudded cells at 37 degrees. Molecular cloning and genetic mapping show that IPL1 is a newly identified gene, whereas IPL2 is allelic to BEM2, which is required for normal bud growth.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baeßler, S.; Nesvizhevsky, V. V.; Pignol, G.

    Quantum states of ultracold neutrons in a gravitational field are characterized through gravitational resonance spectroscopy. This paper discusses systematic effects that appear in the spectroscopic measurements. The discussed frequency shifts-which we call the Stern-Gerlach shift, interference shift, and spectator-state shift-appear in conceivable measurement schemes and have general importance. Lastly, these shifts have to be taken into account in precision experiments.

  3. Identification of atmospheric structure by coherent microwave sounding

    NASA Technical Reports Server (NTRS)

    Birkemeier, W. P.

    1969-01-01

    Two atmospheric probing experiments involving beyond-the-horizon propagation of microwave signals are reported. In the first experiment, Doppler-shift caused by the cross path wind is measured by a phase lock receiver with the common volume displaced in azimuth from the great circle. Variations in the measured Doppler shift values are explained in terms of variations in atmospheric structure. The second experiment makes use of the pseudorandom sounding signal used in a RAKE communication system. Both multipath delay and Doppler shift are provided by the receiver, permitting the cross section of the atmospheric layer structure to be deduced.

  4. Measurement of Critical Contact Angle in a Microgravity Space Experiment

    NASA Technical Reports Server (NTRS)

    Concus, P.; Finn, R.; Weislogel, M.

    1998-01-01

    Mathematical theory predicts that small changes in container shape or in contact angle can give rise to large shifts of liquid in a microgravity environment. This phenomenon was investigated in the Interface Configuration Experiment on board the USML-2 Space Shuttle flight. The experiment's "double proboscis" containers were designed to strike a balance between conflicting requirements of sizable volume of liquid shift (for ease of observation) and abruptness of the shift (for accurate determination of critical contact angle). The experimental results support the classical concept of macroscopic contact angle and demonstrate the role of hysteresis in impeding orientation toward equilibrium.

  5. Measurement of Critical Contact Angle in a Microgravity Space Experiment

    NASA Technical Reports Server (NTRS)

    Concus, P.; Finn, R.; Weislogel, M.

    1998-01-01

    Mathematical theory predicts that small changes in container shape or in contact angle can give rise to large shifts of liquid in a microgravity environment. This phenomenon was investigated in the Interface Configuration Experiment on board the USMT,2 Space Shuttle flight. The experiment's "double proboscis" containers were designed to strike a balance between conflicting requirements of sizable volume of liquid shift (for ease of observation) and abruptness of the shift (for accurate determination of critical contact angle). The experimental results support the classical concept of macroscopic contact angle and demonstrate the role of hysteresis in impeding orientation toward equilibrium.

  6. Concept Maps: A Tool to Prepare for High Fidelity Simulation in Nursing

    ERIC Educational Resources Information Center

    Daley, Barbara J.; Beman, Sarah Black; Morgan, Sarah; Kennedy, Linda; Sheriff, Mandy

    2017-01-01

    In this study, the use of concept mapping as a method to prepare for high fidelity simulated learning experiences was investigated. Fourth year baccalaureate nursing students were taught how to use concept maps as a way to prepare for high fidelity simulated nursing experiences. Students prepared concept maps for two simulated experiences…

  7. Suppression of contrast-related artefacts in phase-measuring structured light techniques

    NASA Astrophysics Data System (ADS)

    Burke, Jan; Zhong, Liang

    2017-06-01

    Optical metrology using phase measurements has benefited significantly from the introduction of phase-shifting methods, first in interferometry, then also in fringe projection and fringe reflection. As opposed to interferometry, the latter two techniques generally use a spatiotemporal phase-shifting approach: A sequence of fringe patterns with varying spacing is used, and a phase map of each is generated by temporal phase shifting, to allow unique assignments of projector or screen pixels to camera pixels. One ubiquitous problem with phase-shifting structured-light techniques is that phase artefacts appear near regions of the image where the modulation amplitude of the projected or reflected fringes changes abruptly, e.g. near dirt/dust particles on the surface in deflectometry or bright-dark object colour transitions in fringe projection. Near the bright-dark boundaries, responses in the phase maps appear that are not plausible as actual surface features. The phenomenon has been known for a long time but is usually ignored because it does not compromise the overall reliability of results. In deflectometry, however, often the objective is to find and classify small defects, and of course it is then important to distinguish between bogus phase responses caused by fringe modulation changes, and actual surface defects. We present, for what we believe is the first time, an analytical derivation of the error terms, study the parameters influencing the phase artefacts (in particular the fringe period), and suggest some simple algorithms to minimise them.

  8. 3D silicon breast surface mapping via structured light profilometry

    NASA Astrophysics Data System (ADS)

    Vairavan, R.; Ong, N. R.; Sauli, Z.; Kirtsaeng, S.; Sakuntasathien, S.; Shahimin, M. M.; Alcain, J. B.; Lai, S. L.; Paitong, P.; Retnasamy, V.

    2017-09-01

    Digital fringe projection technique is one of the promising optical methods for 3D surface imaging as it demonstrates non contact and non invasive characteristics. The potential of this technique matches the requirement for human body evaluation, as it is vital for disease diagnosis and for treatment option selection. Thus, the digital fringe projection has addressed this requirement with its wide clinical related application and studies. However, the application of this technique for 3D surface mapping of the breast is very minimal. Hence, in this work, the application of digital fringe projection for 3D breast surface mapping is reported. Phase shift fringe projection technique was utilized to perform the 3D breast surface mapping. Maiden results have confirmed the feasibility of using the digital fringe projection method for 3D surface mapping of the breast and it can be extended for breast cancer detection.

  9. Infrasound and the avian navigational map

    USGS Publications Warehouse

    Hagstrum, J.T.

    2001-01-01

    Birds can accurately navigate over hundreds to thousands of kilometres, and use celestial and magnetic compass senses to orient their flight. How birds determine their location in order to select the correct homeward bearing (map sense) remains controversial, and has been attributed to their olfactory or magnetic senses. Pigeons can hear infrasound down to 0??05 Hz, and an acoustic avian map is proposed consisting of infrasonic cues radiated from steep-sided topographic features. The source of these infrasonic signals is microseisms continuously generated by interfering oceanic waves. Atmospheric processes affecting the infrasonic map cues can explain perplexing experimental results from pigeon releases. Moreover, four recent disrupted pigeon races in Europe and the north-eastern USA intersected infrasonic shock waves from the Concorde supersonic transport. Having an acoustic map might also allow clock-shifted birds to test their homeward progress and select between their magnetic and solar compasses.

  10. Mapping atomic contact between pentacene and a Au surface using scanning tunneling spectroscopy.

    PubMed

    Song, Young Jae; Lee, Kyuho; Kim, Seong Heon; Choi, Byoung-Young; Yu, Jaejun; Kuk, Young

    2010-03-10

    We mapped spatially varying intramolecular electronic structures on a pentacene-gold interface using scanning tunneling spectroscopy. Along with ab initio calculations based on density functional theory, we found that the directional nature of the d orbitals of Au atoms plays an important role in the interaction at the pentacene-gold contact. The gold-induced interface states are broadened and shifted by various pentacene-gold distances determined by the various registries of a pentacene molecule on a gold substrate.

  11. Analyzing the Signatures of High Red-shift Hydrogen: The Lyman Alpha and 21cm Emission Lines

    NASA Astrophysics Data System (ADS)

    Hansen, Matthew

    Hydrogen line emission is an important window on galaxy formation due to the large abundance of neutral hydrogen in the early Universe. This dissertation comprises two theoretical/computational studies of two types of hydrogen line emission: Lyman alpha emission and escape from young stellar populations, and 21cm radiation from neutral hydrogen clouds at the time of the first luminous objects. The Lyman alpha research concerns the radiative transfer of resonant line radiation from a central source escaping from a multi-phase medium appropriate to young star forming regions. To analyze the properties of this novel radiative transfer problem I develop new theoretical formulations of the problem, substantiated by physically accurate monte carlo simulations of photon scattering and absorption through multi-phase gas geometries. I find that the escape fraction of resonant line photons from young star forming regions--ionized gas filled with neutral hydrogen clouds with low dust content--can exceed the continuum photon escape fraction by up to an order of magnitude. Additionally, I study the effect of gas outflow on the line profile of escaping resonant photons. In light of these results, I discuss why a young normal stellar populations surrounded by a clumpy multi-phase gas outflow can explain the Lyman alpha spectra seen from high red-shift Lyman Alpha Emitters (LAEs). The 21cm research concerns the ionization evolution of the Intergalactic Medium (IGM) during the era of the first luminous objects in the Universe. Large radio-array observatories are currently being built to specifically detect the red-shifted 21cm radiation from neutral hydrogen at red-shifts z ˜ 12 - - 6; the output will be three dimensional maps of ionized regions across the plane of the sky at various red-shift depths. The signal in the resulting ionization maps will be limited by observational noise, mainly from foreground galactic emission in radio frequencies. The research presented here is a unique approach to data mining the planned observational ionization map data. I develop the one-point statistics of the observed 21cm intensity appropriate for the IGM at high red-shifts using a mixture model technique. I show that physically interesting parameters of such mixture models, such as the total ionized gas fraction at a given red-shift slice, can be estimated by applying Maximum Likelihood Expectation to the mixture model of the observed 21cm intensity distribution. The confidence intervals on the expected model parameters are rigorously calculated, and applied to expected detection capabilities of the planned radio-array observatories. I find that at least one of the observatories, the Low Frequency Array (LOFAR), will be able to statistically detect the evolution of the total ionized gas fraction with good precision.

  12. Can you see me? Experiences of nurses working night shift in Australian regional hospitals: a qualitative case study.

    PubMed

    Powell, Idona

    2013-10-01

    To report a study that explored the experiences of night-shift nurses, focusing on employee interrelationships and work satisfaction. Night-shift nurses are a critical component in hospital care making it essential to understand the experiences that give meaning to their work and understand how these nurses and the organization can benefit from their contribution to hospital care. A literature review revealed minimal research in this area. Qualitative case study. A qualitative case study using semi-structured interviews and self-completed diaries was conducted in 2010 in regional public hospitals in Australia. Participants were 14 nurses working nights half or more of their shifts in medical or surgical wards. Thematic analysis identified four major areas of concern: work relationships, work environment, work practices and lifestyle impact. Notably, work relationships were most meaningful for nurses on the same shift; night-shift nurses experienced working conditions inferior to their daytime counterparts including a perception of minimal leadership. Despite limited education opportunities, night shift provided opportunity for professional growth for some nurses with a slippage in skills for others; night shift provided flexibility for family and social activities, yet impeded these same activities, primarily due to pervasive fatigue. Night-shift nurses considered their role critical, yet believed that they were poorly regarded. The strong interpersonal relationships developed between night-shift workers need to be capitalized on whilst developing a more effective leadership model, improved work environment, more equitable professional development, and genuine recognition of the critical role of night nurses. © 2013 Blackwell Publishing Ltd.

  13. Interactions between Human Liver Fatty Acid Binding Protein and Peroxisome Proliferator Activated Receptor Selective Drugs

    PubMed Central

    Velkov, Tony

    2013-01-01

    Fatty acid binding proteins (FABPs) act as intracellular shuttles for fatty acids as well as lipophilic xenobiotics to the nucleus, where these ligands are released to a group of nuclear receptors called the peroxisome proliferator activated receptors (PPARs). PPAR mediated gene activation is ultimately involved in maintenance of cellular homeostasis through the transcriptional regulation of metabolic enzymes and transporters that target the activating ligand. Here we show that liver- (L-) FABP displays a high binding affinity for PPAR subtype selective drugs. NMR chemical shift perturbation mapping and proteolytic protection experiments show that the binding of the PPAR subtype selective drugs produces conformational changes that stabilize the portal region of L-FABP. NMR chemical shift perturbation studies also revealed that L-FABP can form a complex with the PPAR ligand binding domain (LBD) of PPARα. This protein-protein interaction may represent a mechanism for facilitating the activation of PPAR transcriptional activity via the direct channeling of ligands between the binding pocket of L-FABP and the PPARαLBD. The role of L-FABP in the delivery of ligands directly to PPARα via this channeling mechanism has important implications for regulatory pathways that mediate xenobiotic responses and host protection in tissues such as the small intestine and the liver where L-FABP is highly expressed. PMID:23476633

  14. Preparation of a Cobalt(II) Cage: An Undergraduate Laboratory Experiment That Produces a ParaSHIFT Agent for Magnetic Resonance Spectroscopy

    ERIC Educational Resources Information Center

    Burns, Patrick J.; Tsitovich, Pavel B.; Morrow, Janet R.

    2016-01-01

    Laboratory experiments that demonstrate the effect of paramagnetic complexes on chemical shifts and relaxation times of protons are a useful way to introduce magnetic resonance spectroscopy (MRS) probes or magnetic resonance imaging (MRI) contrast agents. In this undergraduate inorganic chemistry experiment, a paramagnetic Co(II) cage complex is…

  15. On the dynamic nature of response criterion in recognition memory: effects of base rate, awareness, and feedback.

    PubMed

    Rhodes, Matthew G; Jacoby, Larry L

    2007-03-01

    The authors examined whether participants can shift their criterion for recognition decisions in response to the probability that an item was previously studied. Participants in 3 experiments were given recognition tests in which the probability that an item was studied was correlated with its location during the test. Results from all 3 experiments indicated that participants' response criteria were sensitive to the probability that an item was previously studied and that shifts in criterion were robust. In addition, awareness of the bases for criterion shifts and feedback on performance were key factors contributing to the observed shifts in decision criteria. These data suggest that decision processes can operate in a dynamic fashion, shifting from item to item.

  16. SeaQuest/E906 Shift Alarm System

    NASA Astrophysics Data System (ADS)

    Kitts, Noah

    2014-09-01

    SeaQuest, Fermilab E906, is a fixed target experiment that measures the Drell-Yan cross-section ratio of proton-proton to proton-deuterium collisions in order to extract the sea anti-quark structure of the proton. SeaQuest will extend the measurements made by E866/NuSea with greater precision at higher Bjorken-x. The continuously running experiment is always being monitored. Those on shift must keep track of all of the detector readouts in order to make sure the experiment is running correctly. As an experiment that is still in its early stages of running, an alarm system for people on shift is being created to provide warnings, such as a plot showing a detector's performance is sufficiently different to need attention. This plan involves python scripts that track live data. When the data shows a problem within the experiment, a corresponding alarm ID is sent to the MySQL database which then sets off an alarm. These alarms, which will alert the person on shift through both an audible and visual response, are important for ensuring that issues do not go unnoticed, and to help make sure the experiment is recording good data.

  17. 3D mouse shape reconstruction based on phase-shifting algorithm for fluorescence molecular tomography imaging system.

    PubMed

    Zhao, Yue; Zhu, Dianwen; Baikejiang, Reheman; Li, Changqing

    2015-11-10

    This work introduces a fast, low-cost, robust method based on fringe pattern and phase shifting to obtain three-dimensional (3D) mouse surface geometry for fluorescence molecular tomography (FMT) imaging. We used two pico projector/webcam pairs to project and capture fringe patterns from different views. We first calibrated the pico projectors and the webcams to obtain their system parameters. Each pico projector/webcam pair had its own coordinate system. We used a cylindrical calibration bar to calculate the transformation matrix between these two coordinate systems. After that, the pico projectors projected nine fringe patterns with a phase-shifting step of 2π/9 onto the surface of a mouse-shaped phantom. The deformed fringe patterns were captured by the corresponding webcam respectively, and then were used to construct two phase maps, which were further converted to two 3D surfaces composed of scattered points. The two 3D point clouds were further merged into one with the transformation matrix. The surface extraction process took less than 30 seconds. Finally, we applied the Digiwarp method to warp a standard Digimouse into the measured surface. The proposed method can reconstruct the surface of a mouse-sized object with an accuracy of 0.5 mm, which we believe is sufficient to obtain a finite element mesh for FMT imaging. We performed an FMT experiment using a mouse-shaped phantom with one embedded fluorescence capillary target. With the warped finite element mesh, we successfully reconstructed the target, which validated our surface extraction approach.

  18. Body position-dependent shift in odor percept present only for perithreshold odors.

    PubMed

    Lundström, Johan N; Boyle, Julie A; Jones-Gotman, Marilyn

    2008-01-01

    We recently demonstrated that a supine position causes a decrease in olfactory sensitivity compared with an upright position. We pursued that initial finding in 3 separate experiments in which we explored the extent of, and mechanism underlying, this phenomenon. In Experiment 1, we replicated the decrease in olfactory sensitivity when in a supine compared with an upright position. In Experiment 2, we measured body position-dependent shifts in physiological variables and sniff measures while smelling suprathreshold odorants and performing a perithreshold odor intensity discrimination task. Olfactory performances were reduced while supine. However, no relationships between the shift in olfactory performances and either the physiological variables or sniff measures were found. In Experiment 3, we determined that there were no position-dependent shifts in ability to discriminate or identify suprathreshold odors or rate them for pleasantness, intensity, or familiarity. However, a drop in scores was observed, and performance was slowed, on a cognitive skill while supine. These results demonstrate a body position-dependent shift in olfactory sensitivity only for perithreshold odors that appears to be mediated by cognitive rather than physiological factors. Implications for olfactory imaging studies are discussed.

  19. Nurses aged over 50 years and their experiences of shift work.

    PubMed

    Clendon, Jill; Walker, Leonie

    2013-10-01

    The Late Career Nurse project examined views and characteristics of nurses working in New Zealand who were born before 1960. This paper focuses on the experiences of such nurses who undertake shift work. The mean age of registered nurses in New Zealand has been rising steadily, and 40% are now aged 50 years or over. While there is substantial literature on the phenomenon and consequences of the ageing nursing workforce, little is known of the particular experiences of nurses aged over 50 years who work shifts. An anonymous online survey was emailed to eligible nurse New Zealand Nurses Organisation members aged over 50 years in February 2012. Quantitative and qualitative analyses of the 3273 responses received were undertaken. Over 45% of respondents worked shifts or flexible hours. While shift work suited many, others noted deleterious effects on family and social relationships, physical and mental health (notably sleep patterns and fatigue), and decreasing tolerance for shift work as they age. Poor scheduling practices were particularly detrimental. Worldwide, workforce ageing means strategies are required to retain older nurses in the workforce. Improved scheduling practices including increasing access to flexible and part time work hours, and development of resources on coping with shift work are recommended. © 2013 John Wiley & Sons Ltd.

  20. A Simple Ultrasonic Experiment Using a Phase Shift Detection Technique.

    ERIC Educational Resources Information Center

    Yunus, W. Mahmood Mat; Ahmad, Maulana

    1996-01-01

    Describes a simple ultrasonic experiment that can be used to measure the purity of liquid samples by detecting variations in the velocity of sound. Uses a phase shift detection technique that incorporates the use of logic gates and a piezoelectric transducer. (JRH)

  1. A study of the utilization of ERTS-1 data from the Wabash River Basin

    NASA Technical Reports Server (NTRS)

    Landgrebe, D. A. (Principal Investigator)

    1974-01-01

    The author has identified the following significant results. The identification and area estimation of crops experiment tested the usefulness of ERTS data for crop survey and produced results indicating that crop statistics could be obtained from ERTS imagery. Soil association mapping results showed that strong relationships exist between ERTS data derived maps and conventional soil maps. Urban land use analysis experiment results indicate potential for accurate gross land use mapping. Water resources mapping demonstrated the feasibility of mapping water bodies using ERTS imagery.

  2. Proton chemical shift tensors determined by 3D ultrafast MAS double-quantum NMR spectroscopy

    NASA Astrophysics Data System (ADS)

    Zhang, Rongchun; Mroue, Kamal H.; Ramamoorthy, Ayyalusamy

    2015-10-01

    Proton NMR spectroscopy in the solid state has recently attracted much attention owing to the significant enhancement in spectral resolution afforded by the remarkable advances in ultrafast magic angle spinning (MAS) capabilities. In particular, proton chemical shift anisotropy (CSA) has become an important tool for obtaining specific insights into inter/intra-molecular hydrogen bonding. However, even at the highest currently feasible spinning frequencies (110-120 kHz), 1H MAS NMR spectra of rigid solids still suffer from poor resolution and severe peak overlap caused by the strong 1H-1H homonuclear dipolar couplings and narrow 1H chemical shift (CS) ranges, which render it difficult to determine the CSA of specific proton sites in the standard CSA/single-quantum (SQ) chemical shift correlation experiment. Herein, we propose a three-dimensional (3D) 1H double-quantum (DQ) chemical shift/CSA/SQ chemical shift correlation experiment to extract the CS tensors of proton sites whose signals are not well resolved along the single-quantum chemical shift dimension. As extracted from the 3D spectrum, the F1/F3 (DQ/SQ) projection provides valuable information about 1H-1H proximities, which might also reveal the hydrogen-bonding connectivities. In addition, the F2/F3 (CSA/SQ) correlation spectrum, which is similar to the regular 2D CSA/SQ correlation experiment, yields chemical shift anisotropic line shapes at different isotropic chemical shifts. More importantly, since the F2/F1 (CSA/DQ) spectrum correlates the CSA with the DQ signal induced by two neighboring proton sites, the CSA spectrum sliced at a specific DQ chemical shift position contains the CSA information of two neighboring spins indicated by the DQ chemical shift. If these two spins have different CS tensors, both tensors can be extracted by numerical fitting. We believe that this robust and elegant single-channel proton-based 3D experiment provides useful atomistic-level structural and dynamical information for a variety of solid systems that possess high proton density.

  3. Proton chemical shift tensors determined by 3D ultrafast MAS double-quantum NMR spectroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Rongchun; Mroue, Kamal H.; Ramamoorthy, Ayyalusamy, E-mail: ramamoor@umich.edu

    2015-10-14

    Proton NMR spectroscopy in the solid state has recently attracted much attention owing to the significant enhancement in spectral resolution afforded by the remarkable advances in ultrafast magic angle spinning (MAS) capabilities. In particular, proton chemical shift anisotropy (CSA) has become an important tool for obtaining specific insights into inter/intra-molecular hydrogen bonding. However, even at the highest currently feasible spinning frequencies (110–120 kHz), {sup 1}H MAS NMR spectra of rigid solids still suffer from poor resolution and severe peak overlap caused by the strong {sup 1}H–{sup 1}H homonuclear dipolar couplings and narrow {sup 1}H chemical shift (CS) ranges, which rendermore » it difficult to determine the CSA of specific proton sites in the standard CSA/single-quantum (SQ) chemical shift correlation experiment. Herein, we propose a three-dimensional (3D) {sup 1}H double-quantum (DQ) chemical shift/CSA/SQ chemical shift correlation experiment to extract the CS tensors of proton sites whose signals are not well resolved along the single-quantum chemical shift dimension. As extracted from the 3D spectrum, the F1/F3 (DQ/SQ) projection provides valuable information about {sup 1}H–{sup 1}H proximities, which might also reveal the hydrogen-bonding connectivities. In addition, the F2/F3 (CSA/SQ) correlation spectrum, which is similar to the regular 2D CSA/SQ correlation experiment, yields chemical shift anisotropic line shapes at different isotropic chemical shifts. More importantly, since the F2/F1 (CSA/DQ) spectrum correlates the CSA with the DQ signal induced by two neighboring proton sites, the CSA spectrum sliced at a specific DQ chemical shift position contains the CSA information of two neighboring spins indicated by the DQ chemical shift. If these two spins have different CS tensors, both tensors can be extracted by numerical fitting. We believe that this robust and elegant single-channel proton-based 3D experiment provides useful atomistic-level structural and dynamical information for a variety of solid systems that possess high proton density.« less

  4. Handling the influence of chemical shift in amplitude-modulated heteronuclear dipolar recoupling solid-state NMR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Basse, Kristoffer; Shankar, Ravi; Bjerring, Morten

    We present a theoretical analysis of the influence of chemical shifts on amplitude-modulated heteronuclear dipolar recoupling experiments in solid-state NMR spectroscopy. The method is demonstrated using the Rotor Echo Short Pulse IRrAdiaTION mediated Cross-Polarization ({sup RESPIRATION}CP) experiment as an example. By going into the pulse sequence rf interaction frame and employing a quintuple-mode operator-based Floquet approach, we describe how chemical shift offset and anisotropic chemical shift affect the efficiency of heteronuclear polarization transfer. In this description, it becomes transparent that the main attribute leading to non-ideal performance is a fictitious field along the rf field axis, which is generated frommore » second-order cross terms arising mainly between chemical shift tensors and themselves. This insight is useful for the development of improved recoupling experiments. We discuss the validity of this approach and present quaternion calculations to determine the effective resonance conditions in a combined rf field and chemical shift offset interaction frame transformation. Based on this, we derive a broad-banded version of the {sup RESPIRATION}CP experiment. The new sequence is experimentally verified using SNNFGAILSS amyloid fibrils where simultaneous {sup 15}N → {sup 13}CO and {sup 15}N → {sup 13}C{sub α} coherence transfer is demonstrated on high-field NMR instrumentation, requiring great offset stability.« less

  5. Simultaneous epicardial and noncontact endocardial mapping of the canine right atrium: simulation and experiment.

    PubMed

    Sabouri, Sepideh; Matene, Elhacene; Vinet, Alain; Richer, Louis-Philippe; Cardinal, René; Armour, J Andrew; Pagé, Pierre; Kus, Teresa; Jacquemet, Vincent

    2014-01-01

    Epicardial high-density electrical mapping is a well-established experimental instrument to monitor in vivo the activity of the atria in response to modulations of the autonomic nervous system in sinus rhythm. In regions that are not accessible by epicardial mapping, noncontact endocardial mapping performed through a balloon catheter may provide a more comprehensive description of atrial activity. We developed a computer model of the canine right atrium to compare epicardial and noncontact endocardial mapping. The model was derived from an experiment in which electroanatomical reconstruction, epicardial mapping (103 electrodes), noncontact endocardial mapping (2048 virtual electrodes computed from a 64-channel balloon catheter), and direct-contact endocardial catheter recordings were simultaneously performed in a dog. The recording system was simulated in the computer model. For simulations and experiments (after atrio-ventricular node suppression), activation maps were computed during sinus rhythm. Repolarization was assessed by measuring the area under the atrial T wave (ATa), a marker of repolarization gradients. Results showed an epicardial-endocardial correlation coefficients of 0.80 and 0.63 (two dog experiments) and 0.96 (simulation) between activation times, and a correlation coefficients of 0.57 and 0.46 (two dog experiments) and 0.92 (simulation) between ATa values. Despite distance (balloon-atrial wall) and dimension reduction (64 electrodes), some information about atrial repolarization remained present in noncontact signals.

  6. Simultaneous Epicardial and Noncontact Endocardial Mapping of the Canine Right Atrium: Simulation and Experiment

    PubMed Central

    Sabouri, Sepideh; Matene, Elhacene; Vinet, Alain; Richer, Louis-Philippe; Cardinal, René; Armour, J. Andrew; Pagé, Pierre; Kus, Teresa; Jacquemet, Vincent

    2014-01-01

    Epicardial high-density electrical mapping is a well-established experimental instrument to monitor in vivo the activity of the atria in response to modulations of the autonomic nervous system in sinus rhythm. In regions that are not accessible by epicardial mapping, noncontact endocardial mapping performed through a balloon catheter may provide a more comprehensive description of atrial activity. We developed a computer model of the canine right atrium to compare epicardial and noncontact endocardial mapping. The model was derived from an experiment in which electroanatomical reconstruction, epicardial mapping (103 electrodes), noncontact endocardial mapping (2048 virtual electrodes computed from a 64-channel balloon catheter), and direct-contact endocardial catheter recordings were simultaneously performed in a dog. The recording system was simulated in the computer model. For simulations and experiments (after atrio-ventricular node suppression), activation maps were computed during sinus rhythm. Repolarization was assessed by measuring the area under the atrial T wave (ATa), a marker of repolarization gradients. Results showed an epicardial-endocardial correlation coefficients of 0.80 and 0.63 (two dog experiments) and 0.96 (simulation) between activation times, and a correlation coefficients of 0.57 and 0.46 (two dog experiments) and 0.92 (simulation) between ATa values. Despite distance (balloon-atrial wall) and dimension reduction (64 electrodes), some information about atrial repolarization remained present in noncontact signals. PMID:24598778

  7. Parallels between Action-Object Mapping and Word-Object Mapping in Young Children

    ERIC Educational Resources Information Center

    Riggs, Kevin J.; Mather, Emily; Hyde, Grace; Simpson, Andrew

    2016-01-01

    Across a series of four experiments with 3- to 4-year-olds we demonstrate how cognitive mechanisms supporting noun learning extend to the mapping of actions to objects. In Experiment 1 (n = 61) the demonstration of a novel action led children to select a novel, rather than a familiar object. In Experiment 2 (n = 78) children exhibited long-term…

  8. Electrostatic frequency maps for amide-I mode of β-peptide: Comparison of molecular mechanics force field and DFT calculations

    NASA Astrophysics Data System (ADS)

    Cai, Kaicong; Zheng, Xuan; Du, Fenfen

    2017-08-01

    The spectroscopy of amide-I vibrations has been widely utilized for the understanding of dynamical structure of polypeptides. For the modeling of amide-I spectra, two frequency maps were built for β-peptide analogue (N-ethylpropionamide, NEPA) in a number of solvents within different schemes (molecular mechanics force field based, GM map; DFT calculation based, GD map), respectively. The electrostatic potentials on the amide unit that originated from solvents and peptide backbone were correlated to the amide-I frequency shift from gas phase to solution phase during map parameterization. GM map is easier to construct with negligible computational cost since the frequency calculations for the samples are purely based on force field, while GD map utilizes sophisticated DFT calculations on the representative solute-solvent clusters and brings insight into the electronic structures of solvated NEPA and its chemical environments. The results show that the maps' predicted amide-I frequencies present solvation environmental sensitivities and exhibit their specific characters with respect to the map protocols, and the obtained vibrational parameters are in satisfactory agreement with experimental amide-I spectra of NEPA in solution phase. Although different theoretical schemes based maps have their advantages and disadvantages, the present maps show their potentials in interpreting the amide-I spectra for β-peptides, respectively.

  9. Using digital inline holographic microscopy and quantitative phase contrast imaging to assess viability of cultured mammalian cells

    NASA Astrophysics Data System (ADS)

    Missan, Sergey; Hrytsenko, Olga

    2015-03-01

    Digital inline holographic microscopy was used to record holograms of mammalian cells (HEK293, B16, and E0771) in culture. The holograms have been reconstructed using Octopus software (4Deep inwater imaging) and phase shift maps were unwrapped using the FFT-based phase unwrapping algorithm. The unwrapped phase shifts were used to determine the maximum phase shifts in individual cells. Addition of 0.5 mM H2O2 to cell media produced rapid rounding of cultured cells, followed by cell membrane rupture. The cell morphology changes and cell membrane ruptures were detected in real time and were apparent in the unwrapped phase shift images. The results indicate that quantitative phase contrast imaging produced by the digital inline holographic microscope can be used for the label-free real time automated determination of cell viability and confluence in mammalian cell cultures.

  10. Real-Time and High-Resolution 3D Face Measurement via a Smart Active Optical Sensor.

    PubMed

    You, Yong; Shen, Yang; Zhang, Guocai; Xing, Xiuwen

    2017-03-31

    The 3D measuring range and accuracy in traditional active optical sensing, such as Fourier transform profilometry, are influenced by the zero frequency of the captured patterns. The phase-shifting technique is commonly applied to remove the zero component. However, this phase-shifting method must capture several fringe patterns with phase difference, thereby influencing the real-time performance. This study introduces a smart active optical sensor, in which a composite pattern is utilized. The composite pattern efficiently combines several phase-shifting fringes and carrier frequencies. The method can remove zero frequency by using only one pattern. Model face reconstruction and human face measurement were employed to study the validity and feasibility of this method. Results show no distinct decrease in the precision of the novel method unlike the traditional phase-shifting method. The texture mapping technique was utilized to reconstruct a nature-appearance 3D digital face.

  11. Real-Time and High-Resolution 3D Face Measurement via a Smart Active Optical Sensor

    PubMed Central

    You, Yong; Shen, Yang; Zhang, Guocai; Xing, Xiuwen

    2017-01-01

    The 3D measuring range and accuracy in traditional active optical sensing, such as Fourier transform profilometry, are influenced by the zero frequency of the captured patterns. The phase-shifting technique is commonly applied to remove the zero component. However, this phase-shifting method must capture several fringe patterns with phase difference, thereby influencing the real-time performance. This study introduces a smart active optical sensor, in which a composite pattern is utilized. The composite pattern efficiently combines several phase-shifting fringes and carrier frequencies. The method can remove zero frequency by using only one pattern. Model face reconstruction and human face measurement were employed to study the validity and feasibility of this method. Results show no distinct decrease in the precision of the novel method unlike the traditional phase-shifting method. The texture mapping technique was utilized to reconstruct a nature-appearance 3D digital face. PMID:28362349

  12. Effects of CO2 injection and Kerogen Maturation on Low-Field Nuclear Magnetic Resonance Response

    NASA Astrophysics Data System (ADS)

    Prasad, M.; Livo, K.

    2017-12-01

    Low-field Nuclear Magnetic Resonance (NMR) is commonly used in petrophysical analysis of petroleum reservoir rocks. NMR experiments record the relaxation and polarization of in-situ hydrogen protons present in gaseous phases such as free-gas intervals and solution gas fluids, bulk fluid phases such as oil and aquifer intervals, and immovable fractions of kerogen and bitumen. Analysis of NMR relaxation spectra is performed to record how fluid composition, maturity, and viscosity change NMR experimental results. We present T1-T2 maps as thermal maturity of a water-saturated, sub-mature Woodford shale is increased at temperatures from 125 to 400 degrees Celsius. Experiments with applied fluid pressure in paraffinic mineral oil and DI water with varying fluid pH have been performed to mimic reservoir conditions in analysis of the relaxation of bulk fluid phases. We have recorded NMR spectra, T1-T2 maps, and fluid diffusion coefficients using a low-field (2 MHz) MagritekTM NMR. CO2 was injected at a pressure of 900 psi in an in house developed NMR pressure vessel made of torlon plastic. Observable 2D NMR shifts in immature kerogen formations as thermal maturity is increased show generation of lighter oils with increased maturity. CO2 injection leads to a decrease in bulk fluid relaxation time that is attributed to viscosity modification with gas presence. pH variation with increased CO2 presence were shown to not effect NMR spectra. From this, fluid properties have been shown to greatly affect NMR readings and must be taken into account for more accurate NMR reservoir characterization.

  13. ON AN ALLEGED TRUTH/FALSITY ASYMMETRY IN CONTEXT SHIFTING EXPERIMENTS

    PubMed Central

    Hansen, Nat

    2012-01-01

    Keith DeRose has argued that context shifting experiments should be designed in a specific way in order to accommodate what he calls a ‘truth/falsity asymmetry’. I explain and critique DeRose's reasons for proposing this modification to contextualist methodology, drawing on recent experimental studies of DeRose's bank cases as well as experimental findings about the verification of affirmative and negative statements. While DeRose's arguments for his particular modification to contextualist methodology fail, the lesson of his proposal is that there is good reason to pay close attention to several subtle aspects of the design of context shifting experiments. PMID:25821248

  14. Cortical Reorganisation during a 30-Week Tinnitus Treatment Program

    PubMed Central

    McMahon, Catherine M.; Ibrahim, Ronny K.; Mathur, Ankit

    2016-01-01

    Subjective tinnitus is characterised by the conscious perception of a phantom sound. Previous studies have shown that individuals with chronic tinnitus have disrupted sound-evoked cortical tonotopic maps, time-shifted evoked auditory responses, and altered oscillatory cortical activity. The main objectives of this study were to: (i) compare sound-evoked brain responses and cortical tonotopic maps in individuals with bilateral tinnitus and those without tinnitus; and (ii) investigate whether changes in these sound-evoked responses occur with amelioration of the tinnitus percept during a 30-week tinnitus treatment program. Magnetoencephalography (MEG) recordings of 12 bilateral tinnitus participants and 10 control normal-hearing subjects reporting no tinnitus were recorded at baseline, using 500 Hz, 1000 Hz, 2000 Hz, and 4000 Hz tones presented monaurally at 70 dBSPL through insert tube phones. For the tinnitus participants, MEG recordings were obtained at 5-, 10-, 20- and 30- week time points during tinnitus treatment. Results for the 500 Hz and 1000 Hz sources (where hearing thresholds were within normal limits for all participants) showed that the tinnitus participants had a significantly larger and more anteriorly located source strengths when compared to the non-tinnitus participants. During the 30-week tinnitus treatment, the participants’ 500 Hz and 1000 Hz source strengths remained higher than the non-tinnitus participants; however, the source locations shifted towards the direction recorded from the non-tinnitus control group. Further, in the left hemisphere, there was a time-shifted association between the trajectory of change of the individual’s objective (source strength and anterior-posterior source location) and subjective measures (using tinnitus reaction questionnaire, TRQ). The differences in source strength between the two groups suggest that individuals with tinnitus have enhanced central gain which is not significantly influenced by the tinnitus treatment, and may result from the hearing loss per se. On the other hand, the shifts in the tonotopic map towards the non-tinnitus participants’ source location suggests that the tinnitus treatment might reduce the disruptions in the map, presumably produced by the tinnitus percept directly or indirectly. Further, the similarity in the trajectory of change across the objective and subjective parameters after time-shifting the perceptual changes by 5 weeks suggests that during or following treatment, perceptual changes in the tinnitus percept may precede neurophysiological changes. Subgroup analyses conducted by magnitude of hearing loss suggest that there were no differences in the 500 Hz and 1000 Hz source strength amplitudes for the mild-moderate compared with the mild-severe hearing loss subgroup, although the mean source strength was consistently higher for the mild-severe subgroup. Further, the mild-severe subgroup had 500 Hz and 1000 Hz source locations located more anteriorly (i.e., more disrupted compared to the control group) compared to the mild-moderate group, although this was trending towards significance only for the 500Hz left hemisphere source. While the small numbers of participants within the subgroup analyses reduce the statistical power, this study suggests that those with greater magnitudes of hearing loss show greater cortical disruptions with tinnitus and that tinnitus treatment appears to reduce the tonotopic map disruptions but not the source strength (or central gain). PMID:26901425

  15. Investigation of the Frequency Shift of a SAD Circuit Loop and the Internal Micro-Cantilever in a Gas Sensor

    PubMed Central

    Guan, Liu; Zhao, Jiahao; Yu, Shijie; Li, Peng; You, Zheng

    2010-01-01

    Micro-cantilever sensors for mass detection using resonance frequency have attracted considerable attention over the last decade in the field of gas sensing. For such a sensing system, an oscillator circuit loop is conventionally used to actuate the micro-cantilever, and trace the frequency shifts. In this paper, gas experiments are introduced to investigate the mechanical resonance frequency shifts of the micro-cantilever within the circuit loop(mechanical resonance frequency, MRF) and resonating frequency shifts of the electric signal in the oscillator circuit (system working frequency, SWF). A silicon beam with a piezoelectric zinc oxide layer is employed in the experiment, and a Self-Actuating-Detecting (SAD) circuit loop is built to drive the micro-cantilever and to follow the frequency shifts. The differences between the two resonating frequencies and their shifts are discussed and analyzed, and a coefficient α related to the two frequency shifts is confirmed. PMID:22163588

  16. Venus mapping

    NASA Technical Reports Server (NTRS)

    Batson, R. M.; Morgan, H. F.; Sucharski, Robert

    1991-01-01

    Semicontrolled image mosaics of Venus, based on Magellan data, are being compiled at 1:50,000,000, 1:10,000,000, 1:5,000,000, and 1:1,000,000 scales to support the Magellan Radar Investigator (RADIG) team. The mosaics are semicontrolled in the sense that data gaps were not filled and significant cosmetic inconsistencies exist. Contours are based on preliminary radar altimetry data that is subjected to revision and improvement. Final maps to support geologic mapping and other scientific investigations, to be compiled as the dataset becomes complete, will be sponsored by the Planetary Geology and Geophysics Program and/or the Venus Data Analysis Program. All maps, both semicontrolled and final, will be published as I-maps by the United States Geological Survey. All of the mapping is based on existing knowledge of the spacecraft orbit; photogrammetric triangulation, a traditional basis for geodetic control on planets where framing cameras were used, is not feasible with the radar images of Venus, although an eventual shift of coordinate system to a revised spin-axis location is anticipated. This is expected to be small enough that it will affect only large-scale maps.

  17. The influence of context boundaries on memory for the sequential order of events.

    PubMed

    DuBrow, Sarah; Davachi, Lila

    2013-11-01

    Episodic memory allows people to reexperience the past by recovering the sequences of events that characterize those prior experiences. Although experience is continuous, people are able to selectively retrieve and reexperience more discrete episodes from their past, raising the possibility that some elements become tightly related to each other in memory, whereas others do not. The current series of experiments was designed to ask how shifts in context during an experience influence how people remember the past. Specifically, we asked how context shifts influence the ability to remember the relative order of past events, a hallmark of episodic memory. We found that memory for the order of events was enhanced within, rather than across, context shifts, or boundaries (Experiment 1). Next, we showed that this relative enhancement in order memory was eliminated when across-item associative processing was disrupted (Experiment 2), suggesting that context shifts have a selective effect on sequential binding. Finally, we provide evidence that the act of making order memory judgments involves the reactivation of representations that bridged the tested items (Experiment 3). Together, these data suggest that boundaries may serve to parse continuous experience into sequences of contextually related events and that this organization facilitates remembering the temporal order of events that share the same context. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  18. USGS advances in integrated, high-resolution sea-floor mapping: inner continental shelf to estuaries

    USGS Publications Warehouse

    Denny, J.F.; Schwab, W.C.; Twichell, D.C.; O'Brien, T.F.; Danforth, W.W.; Foster, D.S.; Bergeron, E.; Worley, C.W.; Irwin, B.J.; Butman, B.; Valentine, P.C.; Baldwin, W.E.; Morton, R.A.; Thieler, E.R.; Nichols, D.R.; Andrews, B.D.

    2007-01-01

    The U.S. Geological Survey (USGS) has been involved in geological mapping of the sea floor for the past thirty years. Early geophysical and acoustic mapping efforts using GLORIA (Geologic LOng Range Inclined ASDIC) a long-range sidescan-sonar system, provided broad-scale imagery of deep waters within the U.S. Exclusive Economic Zone (EEZ). In the early 1990's, research emphasis shifted from deep- to shallow-water environments to address pertinent coastal research and resource management issues. Use of shallow-water, high-resolution geophysical systems has enhanced our understanding of the processes shaping shallow marine environments. However, research within these shallow-water environments continues to present technological challenges.

  19. Retrieval-Induced vs. Context-Induced Forgetting: Does Retrieval-Induced Forgetting Depend on Context Shifts?

    PubMed Central

    Soares, Julia S.; Polack, Cody W.; Miller, Ralph R.

    2015-01-01

    Retrieval-induced forgetting (RIF) is the observation that retrieval of target information causes forgetting of related non-target information. A number of accounts of this phenomenon have been proposed, including a context-shift based account (Jonker, Seli, & Macleod, 2013). This account proposes that RIF occurs due to the context shift from study to retrieval practice, provided there is little context shift between retrieval practice and test phases. We tested both claims put forth by this context account. In Experiment 1, we degraded the context shift between study and retrieval practice by implementing a generative study condition that was highly similar to retrieval practice. We observed no degradation of RIF for these generated exemplars relative to a conventional study control. In Experiment 2, we conceptually replicated the finding of RIF following generative study, and tested whether context differences between each of the three phases affected the size of RIF. Our findings were again contrary to the predictions of the context account. Conjointly, the two experiments refute arguments about the potential inadequacy of our context shifts that could be used to explain either result alone. Overall, our results are most consistent with an inhibitory account of RIF (e.g., Anderson, 2003). PMID:26389628

  20. Shifting Attention Between Visual Dimensions as a Source of Switch Costs.

    PubMed

    Elchlepp, Heike; Best, Maisy; Lavric, Aureliu; Monsell, Stephen

    2017-04-01

    Task-switching experiments have documented a puzzling phenomenon: Advance warning of the switch reduces but does not eliminate the switch cost. Theoretical accounts have posited that the residual switch cost arises when one selects the relevant stimulus-response mapping, leaving earlier perceptual processes unaffected. We put this assumption to the test by seeking electrophysiological markers of encoding a perceptual dimension. Participants categorized a colored letter as a vowel or consonant or its color as "warm" or "cold." Orthogonally to the color manipulation, some colors were eight times more frequent than others, and the letters were in upper- or lowercase. Color frequency modulated the electroencephalogram amplitude at around 150 ms when participants repeated the color-classification task. When participants switched from the letter task to the color task, this effect was significantly delayed. Thus, even when prepared for, a task switch delays or prolongs encoding of the relevant perceptual dimension.

  1. Ultrafast fingerprint indexing for embedded systems

    NASA Astrophysics Data System (ADS)

    Zhou, Ru; Sin, Sang Woo; Li, Dongju; Isshiki, Tsuyoshi; Kunieda, Hiroaki

    2011-10-01

    A novel core-based fingerprint indexing scheme for embedded systems is presented in this paper. Our approach is enabled by our new precise and fast core-detection algorithm with the direction map. It introduces the feature of CMP (core minutiae pair), which describes the coordinates of minutiae and the direction of ridges associated with the minutiae based on the uniquely defined core coordinates. Since each CMP is identical against the shift and rotation of the fingerprint image, the CMP comparison between a template and an input image can be performed without any alignment. The proposed indexing algorithm based on CMP is suitable for embedded systems because the tremendous speed up and the memory reduction are achieved. In fact, the experiments with the fingerprint database FVC2002 show that its speed for the identifications becomes about 40 times faster than conventional approaches, even though the database includes fingerprints with no core.

  2. Slow potentials in a melody recognition task.

    PubMed

    Verleger, R; Schellberg, D

    1990-01-01

    In a previous study, slow negative shifts were found in the EEG of subjects listening to well-known melodies. The two experiments reported here were designed to investigate the variables to which these slow potentials are related. In the first experiment, two opposite hypotheses were tested: The slow shifts might express subjects' acquaintance with the melodies or, on the contrary, the effort invested to identify them. To this end, some of the melodies were presented in the rhythms of other melodies to make recognition more difficult. Further, melodies rated as very well-known and as very unknown were analysed separately. However, the slow shifts were not affected by these experimental variations. Therefore in the second experiment, on the one hand the purely physical parameters intensity and duration were varied, but this variation had no impact on the slow shifts either. On the other hand, recognition was made more difficult by monotonously repeating the pitch of the 4th tone for the rest of some melodies. The slow negative shifts were enhanced with these monotonous melodies. This enhancement supports the "effort" hypothesis. Accordingly, the ofter shifts obtained in both experiments might likewise reflect effort. But since the task was not demanding, it is suggested that these constant shifts reflect the effort invested for coping with the entire underarousing situation rather than with the task. Frequently, slow eye movements occurred in the same time range as the slow potentials, resulting in EOG potentials spreading to the EEG recording sites. Yet results did not change substantially when the EEG recordings were corrected for the influence of EOG potentials.

  3. Experience and limited lighting may affect sleepiness of tunnel workers

    PubMed Central

    2014-01-01

    Background Working on shifts, especially on a night shift, influences the endogenous sleep regulation system leading to diminished sleep time and increased somnolence. We attempted to evaluate the impact of shifts on sleepiness and correlate the sleepiness score to the experience in a shift schedule. Materials and methods This cross-sectional study consists of 42 male and 2 female workers involved in a tunnel construction. They underwent spirometry, pulse oximetry and were asked to complete the Epworth Sleepiness Scale questionnaire. Results Statistical analysis revealed that workers of lower Epworth had a mean age of 43.6 years, compared to the mean age of 36.4 years of workers with higher Epworth. Furthermore, workers of lower Epworth were characterized by a mean number of shift years equal to 14.8, while those of higher Epworth possessed a mean number of shift years equal to 8. The shift schedule did not reveal any statistically significant correlation. Conclusions Workers employed for a longer time had diminished sleepiness. However, there is no relationship between night shifts and sleepiness, possibly because of exposure to artificial lighting in the construction site. PMID:24993796

  4. Experience and limited lighting may affect sleepiness of tunnel workers.

    PubMed

    Lykouras, Dimosthenis; Karkoulias, Kiriakos; Patouchas, Dimitrios; Lakoumentas, John; Sampsonas, Fotis; Tranou, Magdalini-Konstantina; Faliagka, Evanthia; Tsakalidis, Athanasios; Spiropoulos, Kostas

    2014-07-03

    Working on shifts, especially on a night shift, influences the endogenous sleep regulation system leading to diminished sleep time and increased somnolence. We attempted to evaluate the impact of shifts on sleepiness and correlate the sleepiness score to the experience in a shift schedule. This cross-sectional study consists of 42 male and 2 female workers involved in a tunnel construction. They underwent spirometry, pulse oximetry and were asked to complete the Epworth Sleepiness Scale questionnaire. Statistical analysis revealed that workers of lower Epworth had a mean age of 43.6 years, compared to the mean age of 36.4 years of workers with higher Epworth. Furthermore, workers of lower Epworth were characterized by a mean number of shift years equal to 14.8, while those of higher Epworth possessed a mean number of shift years equal to 8. The shift schedule did not reveal any statistically significant correlation. Workers employed for a longer time had diminished sleepiness. However, there is no relationship between night shifts and sleepiness, possibly because of exposure to artificial lighting in the construction site.

  5. Bacterial Community and Spoilage Profiles Shift in Response to Packaging in Yellow-Feather Broiler, a Highly Popular Meat in Asia

    PubMed Central

    Wang, Huhu; Zhang, Xinxiao; Wang, Guangyu; Jia, Kun; Xu, Xinglian; Zhou, Guanghong

    2017-01-01

    The consumption of yellow-feathered broiler has been advocated for purchasing with chilled meat rather than live broilers in Asia due to the outbreaks of animal influenza. Here, the microbial community of chilled yellow-feathered broiler response to modified-air packaging (MAP, 80% CO2/20% N2) and penetrated-air packaging (PAP, air-filling) during storage was revealed by a combination of whole-metagenome shotgun sequencing and traditional isolation methods, and the volatile organic compounds and proteolytic activity of representative dominant isolates were also accessed. The results revealed that MAP prolonged shelf life from 4 to 8 days compared to PAP, when the numbers of total viable counts and lactic acid bacteria reached more than 7 log CFU/g. Aeromonas, Acinetobacter, Escherichia, and Streptococcus occupied the bacteria communities in initial broiler carcasses. MAP dramatically increased the bacteria diversity during storage compared to PAP. Clear shifts of the dominant bacteria species were obviously observed, with the top genera of Aeromonas, Lactococcus, Serratia, and Shewanella in MAP, whereas the microbial communities in PAP were largely dominated by Pseudomonas. The isolates of Pseudomonas from PAP carcasses and Aeromonas from MAP carcasses displayed strong proteolytic activities. Meanwhile, the principal component analysis based on the volatile organic compounds indicated that the metabolic profiles greatly varied between each treatment, and no link between the natural odor of spoilage meat in situ and the volatile odor of the dominant isolates incubated in standard culture was found. These data could lead to new insights into the bacteria communities of yellow-feathered broiler meat during storage and would benefit the development of novel preservative approaches. PMID:29312261

  6. Individual vulnerability to insomnia, excessive sleepiness and shift work disorder amongst healthcare shift workers. A systematic review.

    PubMed

    Booker, Lauren A; Magee, Michelle; Rajaratnam, Shantha M W; Sletten, Tracey L; Howard, Mark E

    2018-03-27

    Shift workers often experience reduced sleep quality, duration and/or excessive sleepiness due to the imposed conflict between work and their circadian system. About 20-30% of shift workers experience prominent insomnia symptoms and excessive daytime sleepiness consistent with the circadian rhythm sleep disorder known as shift work disorder. Individual factors may influence this vulnerability to shift work disorder or sleep-related impairment associated with shift work. This paper was registered with Prospero and was conducted using recommended standards for systematic reviews and meta-analyses. Published literature that measured sleep-related impairment associated with shift work including reduced sleep quality and duration and increased daytime sleepiness amongst healthcare shift workers and explored characteristics associated with individual variability were reviewed. Fifty-eight studies were included. Older age, morning-type, circadian flexibility, being married or having children, increased caffeine intake, higher scores on neuroticism and lower on hardiness were related to a higher risk of sleep-related impairment in response to shift work, whereas physical activity was a protective factor. The review highlights the diverse range of measurement tools used to evaluate the impact of shift work on sleep. Use of standardised and validated tools would enable cross-study comparisons. Longitudinal studies are required to establish causal relationships between individual factors and the development of shift work disorder. Copyright © 2018 Elsevier Ltd. All rights reserved.

  7. Connecting today's climates to future climate analogs to facilitate movement of species under climate change.

    PubMed

    Littlefield, Caitlin E; McRae, Brad H; Michalak, Julia L; Lawler, Joshua J; Carroll, Carlos

    2017-12-01

    Increasing connectivity is an important strategy for facilitating species range shifts and maintaining biodiversity in the face of climate change. To date, however, few researchers have included future climate projections in efforts to prioritize areas for increasing connectivity. We identified key areas likely to facilitate climate-induced species' movement across western North America. Using historical climate data sets and future climate projections, we mapped potential species' movement routes that link current climate conditions to analogous climate conditions in the future (i.e., future climate analogs) with a novel moving-window analysis based on electrical circuit theory. In addition to tracing shifting climates, the approach accounted for landscape permeability and empirically derived species' dispersal capabilities. We compared connectivity maps generated with our climate-change-informed approach with maps of connectivity based solely on the degree of human modification of the landscape. Including future climate projections in connectivity models substantially shifted and constrained priority areas for movement to a smaller proportion of the landscape than when climate projections were not considered. Potential movement, measured as current flow, decreased in all ecoregions when climate projections were included, particularly when dispersal was limited, which made climate analogs inaccessible. Many areas emerged as important for connectivity only when climate change was modeled in 2 time steps rather than in a single time step. Our results illustrate that movement routes needed to track changing climatic conditions may differ from those that connect present-day landscapes. Incorporating future climate projections into connectivity modeling is an important step toward facilitating successful species movement and population persistence in a changing climate. © 2017 Society for Conservation Biology.

  8. Magnetic susceptibility induced echo time shifts: Is there a bias in age-related fMRI studies?

    PubMed Central

    Ngo, Giang-Chau; Wong, Chelsea N.; Guo, Steve; Paine, Thomas; Kramer, Arthur F.; Sutton, Bradley P.

    2016-01-01

    Purpose To evaluate the potential for bias in functional MRI (fMRI) aging studies resulting from age-related differences in magnetic field distributions which can impact echo time and functional contrast. Materials and Methods Magnetic field maps were taken on 31 younger adults (age: 22 ± 2.9 years) and 46 older adults (age: 66 ± 4.5 years) on a 3 T scanner. Using the spatial gradients of the magnetic field map for each participant, an echo planar imaging (EPI) trajectory was simulated. The effective echo time, time at which the k-space trajectory is the closest to the center of k-space, was calculated. This was used to examine both within-subject and across-age-group differences in the effective echo time maps. The Blood Oxygenation Level Dependent (BOLD) percent signal change resulting from those echo time shifts was also calculated to determine their impact on fMRI aging studies. Result For a single subject, the effective echo time varied as much as ± 5 ms across the brain. An unpaired t-test between the effective echo time across age group resulted in significant differences in several regions of the brain (p<0.01). The difference in echo time was only approximately 1 ms, however which is not expected to have an important impact on BOLD fMRI percent signal change (< 4%). Conclusion Susceptibility-induced magnetic field gradients induce local echo time shifts in gradient echo fMRI images, which can cause variable BOLD sensitivity across the brain. However, the age-related differences in BOLD signal are expected to be small for an fMRI study at 3 T. PMID:27299727

  9. Towards Longitudinal Mapping of Extracellular pH in Gliomas

    PubMed Central

    Huang, Yuegao; Coman, Daniel; Herman, Peter; Rao, Jyotsna U.; Maritim, Samuel; Hyder, Fahmeed

    2016-01-01

    Biosensor Imaging of Redundant Deviation in Shifts (BIRDS), an ultrafast chemical shift imaging technique, requires infusion of paramagnetic probes like 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate (DOTP8−) complexed with thulium (Tm3+) ion (i.e., TmDOTP5−), where the pH-sensitive resonances of hyperfine-shifted nonexchangeable protons contained within the paramagnetic magnetic resonance probe are detected. While imaging extracellular pH (pHe) with BIRDS meets an important cancer research need by mapping the intratumoral-peritumoral pHe gradient, the surgical intervention used to raise the probe’s plasma concentration limits longitudinal scans on the same subject. Here we describe using probenecid (i.e., an organic anion transporter inhibitor) to temporarily restrict renal clearance of TmDOTP5−, thereby facilitating molecular imaging by BIRDS without surgical intervention. Co-infusion of probenecid with TmDOTP5− increased the probe’s distribution into various organs, including the brain, compared with when infusing TmDOTP5− alone. In vivo BIRDS data using probenecid/TmDOTP5− co-infusion method in rats bearing RG2, 9L, and U87 brain tumors showed intratumoral-peritumoral pHe gradients that were unaffected by the probe dose. This co-infusion method can be used for pHe mapping with BIRDS in preclinical models for tumor characterization and therapeutic monitoring given the possibility of repeated scans with BIRDS (e.g., over days and even weeks) in the same subject. The longitudinal pHe readout by probenecid/TmDOTP5− co-infusion method for BIRDS adds translational value in tumor assessment and treatment. PMID:27472471

  10. Offline multiple adaptive planning strategy for concurrent irradiation of the prostate and pelvic lymph nodes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Qi, Peng; Xia, Ping, E-mail: xiap@ccf.org; Pouliot, Jean

    2014-02-15

    Purpose: Concurrent irradiation of the prostate and pelvic lymph nodes (PLNs) can be challenging due to the independent motion of the two target volumes. To address this challenge, the authors have proposed a strategy referred to as Multiple Adaptive Planning (MAP). To minimize the number of MAP plans, the authors’ previous work only considered the prostate motion in one major direction. After analyzing the pattern of the prostate motion, the authors investigated a practical number of intensity-modulated radiotherapy (IMRT) plans needed to accommodate the prostate motion in two major directions simultaneously. Methods: Six patients, who received concurrent irradiation of themore » prostate and PLNs, were selected for this study. Nine MAP-IMRT plans were created for each patient with nine prostate contours that represented the prostate at nine locations with respect to the PLNs, including the original prostate contour and eight contours shifted either 5 mm in a single anterior-posterior (A-P), or superior-inferior (S-I) direction, or 5 mm in both A-P and S-I directions simultaneously. From archived megavoltage cone beam CT (MV-CBCT) and a dual imaging registration, 17 MV-CBCTs from 33 available MV-CBCT from these patients showed large prostate displacements (>3 mm in any direction) with respect to the pelvic bones. For each of these 17 fractions, one of nine MAP-IMRT plans was retrospectively selected and applied to the MV-CBCT for dose calculation. For comparison, a simulated isocenter-shifting plan and a reoptimized plan were also created for each of these 17 fractions. The doses to 95% (D95) of the prostate and PLNs, and the doses to 5% (D5) of the rectum and bladder were calculated and analyzed. Results: For the prostate, D95 > 97% of the prescription dose was observed in 16, 16, and 17 of 17 fractions for the MAP, isocenter-shifted, and reoptimized plans, respectively. For PLNs, D95 > 97% of the prescription doses was observed in 10, 3, and 17 of 17 fractions for the three types of verification plans, respectively. The D5 (mean ± SD) of the rectum was 45.78 ± 5.75, 45.44 ± 4.64, and 44.64 ± 2.71 Gy, and the D5 (mean ± SD) of the bladder was 45.18 ± 2.70, 46.91 ± 3.04, and 45.67 ± 3.61 Gy for three types of verification plans, respectively. Conclusions: The MAP strategy with nine IMRT plans to accommodate the prostate motions in two major directions achieved good dose coverage to the prostate and PLNs. The MAP approach can be immediately used in clinical practice without requiring extra hardware and software.« less

  11. Impressionist Landscape Cartography

    NASA Astrophysics Data System (ADS)

    Todd, Stella W.

    2018-05-01

    Cartography helps to show us the world in which we reside by providing us a framework to explore space. We can select myriad themes to represent what is relevant to our lives: physical characteristics, human behaviors, hazards, opportunities. Themes are represented on a continuum between real-world images and pure abstractions. How we define cartography and what we expect from it changes with society and technology. We are now inundated with data but we still struggle with expressing our personal geographic experiences through cartography. In this age of information we have become more cognizant of our individual experience of place and our need to determine our own paths and therefore create our own maps. In order to reflect our journey we can add individual details to cartographic products or generalize information to concentrate on what is meaningful to us. Since time and space are interrelated we experience geography by viewing the landscape as changing scenes over time. This experience is both spatial and temporal since we experience geography by moving through space. Experiencing each scene is a separate event. This paper expands the personalization of maps to include our impressions of the travel experience. Rather than add art to cartography it provides geographic reference to art. It explores the use of a series of quick sketches drawn while traveling along roads using a single drawing pad to produce a time series of interpreted landscapes. With the use of geographic time stamps from global positioning systems these sketches are converted from a drawing to a map documenting the path of movement. Although the map scale varies between sketch entries each scene impression can be linked to one or more maps of consistent scale. The result is an artistic piece that expresses a dynamic geographic experience that can be viewed in conjunction with more traditional maps. Unlike mental maps which are constructed from memory, these maps reflect our direct impressions of the landscape. The use of art can help us convey our experience.

  12. Mapping the Speech Code: Cortical Responses Linking the Perception and Production of Vowels

    PubMed Central

    Schuerman, William L.; Meyer, Antje S.; McQueen, James M.

    2017-01-01

    The acoustic realization of speech is constrained by the physical mechanisms by which it is produced. Yet for speech perception, the degree to which listeners utilize experience derived from speech production has long been debated. In the present study, we examined how sensorimotor adaptation during production may affect perception, and how this relationship may be reflected in early vs. late electrophysiological responses. Participants first performed a baseline speech production task, followed by a vowel categorization task during which EEG responses were recorded. In a subsequent speech production task, half the participants received shifted auditory feedback, leading most to alter their articulations. This was followed by a second, post-training vowel categorization task. We compared changes in vowel production to both behavioral and electrophysiological changes in vowel perception. No differences in phonetic categorization were observed between groups receiving altered or unaltered feedback. However, exploratory analyses revealed correlations between vocal motor behavior and phonetic categorization. EEG analyses revealed correlations between vocal motor behavior and cortical responses in both early and late time windows. These results suggest that participants' recent production behavior influenced subsequent vowel perception. We suggest that the change in perception can be best characterized as a mapping of acoustics onto articulation. PMID:28439232

  13. Tip-Enhanced Raman Nanographs: Mapping Topography and Local Electric Fields

    DOE PAGES

    El-Khoury, Patrick Z.; Gong, Yu; Abellan, Patricia; ...

    2015-03-05

    We report tip-enhanced Raman scattering experiments in which topographic and local electric field images are recorded simultaneously. We employ a Raman-active 4,4’-dimercaptostilbene (DMS)-coated gold tip of an atomic force microscope to map the topography and image electric fields localized at nanometric (20 and 5 nm-wide) slits lithographically etched in silver. Bi-modal imaging is feasible by virtue of the recorded scanning probe position-dependent frequency-resolved optical response, which can be sub-divided into two components. The first is a 500-2250 cm-1 Raman-shifted signal, characteristic of DMS. The molecular response reports on topography through intensity contrast in the absence/presence of a plasmonic junction formedmore » between the scanning probe and patterned silver surface. Here, we demonstrate that sub-15 nm spatial resolution is attainable using a 30 nm DMS-coated gold tip. The second response consists of two correlated sub-500 cm-1 signals arising from mirror-like reflections of (i) the incident laser, and (ii) the Raman scattered response of an underlying glass support (at 100-500 cm-1) off the gold tip. We show that both the low-wavenumber signals trace the local electric fields in the vicinity of the nanometric slits.« less

  14. Decoding the cortical transformations for visually guided reaching in 3D space.

    PubMed

    Blohm, Gunnar; Keith, Gerald P; Crawford, J Douglas

    2009-06-01

    To explore the possible cortical mechanisms underlying the 3-dimensional (3D) visuomotor transformation for reaching, we trained a 4-layer feed-forward artificial neural network to compute a reach vector (output) from the visual positions of both the hand and target viewed from different eye and head orientations (inputs). The emergent properties of the intermediate layers reflected several known neurophysiological findings, for example, gain field-like modulations and position-dependent shifting of receptive fields (RFs). We performed a reference frame analysis for each individual network unit, simulating standard electrophysiological experiments, that is, RF mapping (unit input), motor field mapping, and microstimulation effects (unit outputs). At the level of individual units (in both intermediate layers), the 3 different electrophysiological approaches identified different reference frames, demonstrating that these techniques reveal different neuronal properties and suggesting that a comparison across these techniques is required to understand the neural code of physiological networks. This analysis showed fixed input-output relationships within each layer and, more importantly, within each unit. These local reference frame transformation modules provide the basic elements for the global transformation; their parallel contributions are combined in a gain field-like fashion at the population level to implement both the linear and nonlinear elements of the 3D visuomotor transformation.

  15. Conflict escalation in paediatric services: findings from a qualitative study

    PubMed Central

    Forbat, Liz; Teuten, Bea; Barclay, Sarah

    2015-01-01

    Objective To explore clinician and family experiences of conflict in paediatric services, in order to map the trajectory of conflict escalation. Design Qualitative interview study, employing extreme-case sampling. Interviews were analysed using an iterative thematic approach to identify common themes regarding the experience and escalation of conflict. Participants Thirty-eight health professionals and eight parents. All participants had direct experience of conflict, including physical assault and court proceedings, at the interface of acute and palliative care. Setting Two teaching hospitals, one district general hospital and two paediatric hospices in England, in 2011. Results Conflicts escalate in a predictable manner. Clearly identifiable behaviours by both clinicians and parents are defined as mild, moderate and severe. Mild describes features like the insensitive use of language and a history of unresolved conflict. Moderate involves a deterioration of trust, and a breakdown of communication and relationships. Severe marks disintegration of working relationships, characterised by behavioural changes including aggression, and a shift in focus from the child's best interests to the conflict itself. Though conflicts may remain at one level, those which escalated tended to move sequentially from one level to the next. Conclusions Understanding how conflicts escalate provides clinicians with a practical, evidence-based framework to identify the warning signs of conflict in paediatrics. PMID:25940425

  16. Survival of the Partial Reinforcement Extinction Effect after Contextual Shifts

    ERIC Educational Resources Information Center

    Boughner, Robert L.; Papini, Mauricio R.

    2006-01-01

    The effects of contextual shifts on the partial reinforcement extinction effect (PREE) were studied in autoshaping with rats. Experiment 1 established that the two contexts used subsequently were easily discriminable and equally salient. In Experiment 2, independent groups of rats received acquisition training under partial reinforcement (PRF) or…

  17. Shape shifting: Local landmarks interfere with navigation by, and recognition of, global shape.

    PubMed

    Buckley, Matthew G; Smith, Alastair D; Haselgrove, Mark

    2014-03-01

    An influential theory of spatial navigation states that the boundary shape of an environment is preferentially encoded over and above other spatial cues, such that it is impervious to interference from alternative sources of information. We explored this claim with 3 intradimensional-extradimensional shift experiments, designed to examine the interaction of landmark and geometric features of the environment in a virtual navigation task. In Experiments 1 and 2, participants were first required to find a hidden goal using information provided by the shape of the arena or landmarks integrated into the arena boundary (Experiment 1) or within the arena itself (Experiment 2). Participants were then transferred to a different-shaped arena that contained novel landmarks and were again required to find a hidden goal. In both experiments, participants who were navigating on the basis of cues that were from the same dimension that was previously relevant (intradimensional shift) learned to find the goal significantly faster than participants who were navigating on the basis of cues that were from a dimension that was previously irrelevant (extradimensional shift). This suggests that shape information does not hold special status when learning about an environment. Experiment 3 replicated Experiment 2 and also assessed participants' recognition of the global shape of the navigated arenas. Recognition was attenuated when landmarks were relevant to navigation throughout the experiment. The results of these experiments are discussed in terms of associative and non-associative theories of spatial learning.

  18. Frame of reference for electronic maps - The relevance of spatial cognition, mental rotation, and componential task analysis

    NASA Technical Reports Server (NTRS)

    Wickens, Christopher D.; Aretz, Anthony; Harwood, Kelly

    1989-01-01

    Three experiments are reported that examine the difference between north-up and track-up maps for airborne navigation. The results of the first two experiments, conducted in a basic laboratory setting, identified the cost associated with mental rotation, when a north-up map is used. However, the data suggest that these costs are neither large nor consistent. The third experiment examined a range of tasks in a higher fidelity helicopter flight simulation, and associated the costs of north-up maps with a cognitive component related to orientation, and the costs of track-up maps with a cognitive component related to inconsistent landmark location. Different tasks are associated with different dependence on these components. The results are discussed in terms of their implications for map design, and for cognitive models of navigational processes.

  19. Bodily maps of emotions.

    PubMed

    Nummenmaa, Lauri; Glerean, Enrico; Hari, Riitta; Hietanen, Jari K

    2014-01-14

    Emotions are often felt in the body, and somatosensory feedback has been proposed to trigger conscious emotional experiences. Here we reveal maps of bodily sensations associated with different emotions using a unique topographical self-report method. In five experiments, participants (n = 701) were shown two silhouettes of bodies alongside emotional words, stories, movies, or facial expressions. They were asked to color the bodily regions whose activity they felt increasing or decreasing while viewing each stimulus. Different emotions were consistently associated with statistically separable bodily sensation maps across experiments. These maps were concordant across West European and East Asian samples. Statistical classifiers distinguished emotion-specific activation maps accurately, confirming independence of topographies across emotions. We propose that emotions are represented in the somatosensory system as culturally universal categorical somatotopic maps. Perception of these emotion-triggered bodily changes may play a key role in generating consciously felt emotions.

  20. Qualitative analysis and conceptual mapping of patient experiences in home health care.

    PubMed

    Lines, Lisa M; Anderson, Wayne L; Blackmon, Brian D; Pronier, Cristalle R; Allen, Rachael W; Kenyon, Anne E

    2018-01-01

    This study explored patient experiences in home health care through a literature review, focus groups, and interviews. Our goal was to develop a conceptual map of home health care patient experience domains. The conceptual map identifies technical and personal spheres of care, relating prior studies to new focus group and interview findings and identifying the most important domains of care. Study participants (n = 35) most frequently reported the most important domain as staff who are caring, supportive, patient, empathetic, respectful, and considerate (endorsed by 29% of participants). The conceptual map includes 114 discrete domains.

  1. The Mental Manipulation of Cognitive Maps in Children and Adults.

    ERIC Educational Resources Information Center

    Hardwick, Douglas A.; McIntyre, Curtis W.

    Two experiments compared the cognitive maps (mental representations of the spatial environment) of first graders, fifth graders and college students, and investigated developmental changes in the ability to manipulate cognitive maps mentally. In the first experiment, subjects were asked to move from stationpoint to stationpoint and at each, to…

  2. High-resolution maps of real and illusory tactile activation in primary somatosensory cortex in individual monkeys with functional magnetic resonance imaging and optical imaging.

    PubMed

    Chen, Li M; Turner, Gregory H; Friedman, Robert M; Zhang, Na; Gore, John C; Roe, Anna W; Avison, Malcolm J

    2007-08-22

    Although blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) has been widely used to explore human brain function, questions remain regarding the ultimate spatial resolution of positive BOLD fMRI, and indeed the extent to which functional maps revealed by positive BOLD correlate spatially with maps obtained with other high-spatial-resolution mapping techniques commonly used in animals, such as optical imaging of intrinsic signal (OIS) and single-unit electrophysiology. Here, we demonstrate that the positive BOLD signal at 9.4T can reveal the fine topography of individual fingerpads in single-condition activation maps in nonhuman primates. These digit maps are similar to maps obtained from the same animal using intrinsic optical imaging. Furthermore, BOLD fMRI reliably resolved submillimeter spatial shifts in activation in area 3b previously identified with OIS (Chen et al., 2003) as neural correlates of the "funneling illusion." These data demonstrate that at high field, high-spatial-resolution topographic maps can be achieved using the positive BOLD signal, weakening previous notions regarding the spatial specificity of the positive BOLD signal.

  3. Activation of the Basolateral Amygdala Induces Long-Term Enhancement of Specific Memory Representations in the Cerebral Cortex

    PubMed Central

    Chavez, Candice M.; McGaugh, James L.; Weinberger, Norman M.

    2013-01-01

    The basolateral amygdala (BLA) modulates memory, particularly for arousing or emotional events, during post-training periods of consolidation. It strengthens memories whose substrates in part or whole are stored remotely, in structures such as the hippocampus, striatum and cerebral cortex. However, the mechanisms by which the BLA influences distant memory traces are unknown, largely because of the need for identifiable target mnemonic representations. Associative tuning plasticity in the primary auditory cortex (A1) constitutes a well-characterized candidate specific memory substrate that is ubiquitous across species, tasks and motivational states. When tone predicts reinforcement, the tuning of cells in A1 shifts toward or to the signal frequency within its tonotopic map, producing an over-representation of behaviorally important sounds. Tuning shifts have the cardinal attributes of forms of memory, including associativity, specificity, rapid induction, consolidation and long-term retention and are therefore likely memory representations. We hypothesized that the BLA strengthens memories by increasing their cortical representations. We recorded multiple unit activity from A1 of rats that received a single discrimination training session in which two tones (2.0 s) separated by 1.25 octaves were either paired with brief electrical stimulation (400 ms) of the BLA (CS+) or not (CS−). Frequency response areas generated by presenting a matrix of test tones (0.5–53.82 kHz, 0–70 dB) were obtained before training and daily for three weeks post-training. Tuning both at threshold and above threshold shifted predominantly toward the CS+ beginning on Day 1. Tuning shifts were maintained for the entire three weeks. Absolute threshold and bandwidth decreased, producing less enduring increases in sensitivity and selectivity. BLA-induced tuning shifts were associative, highly specific and long-lasting. We propose that the BLA strengthens memory for important experiences by increasing the number of neurons that come to best represent that event. Traumatic, intrusive memories might reflect abnormally extensive representational networks due to hyper-activity of the BLA consequent to the release of excessive amounts of stress hormones. PMID:23266792

  4. Triage level assignment and nurse characteristics and experience.

    PubMed

    Gómez-Angelats, Elisenda; Miró, Òscar; Bragulat Baur, Ernesto; Antolín Santaliestra, Alberto; Sánchez Sánchez, Miquel

    2018-06-01

    To study the relation between nursing staff demographics and experience and their assignment of triage level in the emergency department. One-year retrospective observational study in the triage area of a tertiary care urban university hospital that applies the Andorran-Spanish triage model. Variables studied were age, gender, nursing experience, triage experience, shift, usual level of emergency work the nurse undertakes, number of triage decisions made, and percentage of patients assigned to each level. Fifty nurses (5 men, 45 women) with a mean (SD) age of 45 (9) years triaged 67 803 patients during the year. Nurses classified more patients in level 5 on the morning shift (7.9%) than on the afternoon shift (5.5%) (P=.003). The difference in the rate of level-5 triage classification became significant when nurses were older (β = 0.092, P=.037) and experience was greater (β = 0.103, P=.017). The number of triages recorded by a nurse was significantly and directly related to the percentage of patients assigned to level 3 (β = 0.003, P=.006) and inversely related to the percentages assigned to level 4 (β = -0.002, P=.008) and level 5 (β = -0.001, P=.017). We found that triage level assignments were related to age, experience, shift, and total number of patients triaged by a nurse.

  5. Context effects on tempo and pleasantness judgments for Beatles songs.

    PubMed

    Rashotte, Matthew A; Wedell, Douglas H

    2012-04-01

    Context effects on tempo and pleasantness judgments of different tempos were demonstrated in three experiments using Beatles songs. In Experiments 1 and 2, we explored how listening to versions of the same song that were played at different tempos affected tempo and pleasantness ratings. In both experiments, contrast effects were found on judgments of tempo, with target tempos rated faster when context tempos were slow than when they were fast. In both experiments, we also showed that the peak of the pleasantness rating function shifted toward the values of the context tempos, reflecting disordinal context effects on pleasantness relationships. Familiarity with the songs did not moderate these effects, and shifts in tempo ratings did not correlate with shifts in most pleasant target tempos when context was manipulated within subjects. In Experiment 3, we examined how manipulations of context tempos for one song affected judgments of the same song as compared with judgments of other more or less similar songs. For tempo ratings, contrast effects transferred to ratings of a similar song, but for pleasantness ratings, assimilative shifts of ideals were found only for the same song and not for similar songs. This pattern of results was supportive of independent bases for the two context effects.

  6. Object-based attention in chimpanzees (Pan troglodytes).

    PubMed

    Ushitani, Tomokazu; Imura, Tomoko; Tomonaga, Masaki

    2010-03-17

    We conducted three experiments to investigate how object-based components contribute to the attentional processes of chimpanzees and to examine how such processes operate with regard to perceptually structured objects. In Experiment 1, chimpanzees responded to a spatial cueing task that required them to touch a target appearing at either end of two parallel rectangles. We compared the time involved in shifting attention (cost of attentional shift) when the locations of targets were cued and non cued. Results showed that the cost of the attentional shift within one rectangle was smaller than that beyond the object's boundary, demonstrating object-based attention in chimpanzees. The results of Experiment 2, conducted with different stimulus configurations, replicated the results of Experiment 1, supporting that object-based attention operates in chimpanzees. In Experiment 3, the cost of attentional shift within a cued but partly occluded rectangle was shorter than that within a rectangle that was cued but divided in the middle. The results suggest that the attention of chimpanzees is activated not only by an explicit object but also by fragmented patches represented as an object at a higher-order perceptual level. Chimpanzees' object-based attention may be similar to that of humans. Copyright 2010 Elsevier Ltd. All rights reserved.

  7. Phase-Shift Interferometry with a Digital Photocamera

    ERIC Educational Resources Information Center

    Vannoni, Maurizio; Trivi, Marcelo; Molesini, Giuseppe

    2007-01-01

    A phase-shift interferometry experiment is proposed, working on a Twyman-Green optical configuration with additional polarization components. A guideline is provided to modern phase-shift interferometry, using concepts and laboratory equipment at the level of undergraduate optics courses. (Contains 5 figures.)

  8. The interprofessional learning experience: Findings from a qualitative study based in an outpatient setting.

    PubMed

    Jakobsen, Flemming; Mørcke, Anne Mette; Hansen, Torben Bæk

    2017-09-01

    Clinical interprofessional education has traditionally taken place in hospital wards, but much diagnosis and treatment have shifted to the outpatient setting. The logical consequence is to shift more students' clinical placements from the "bedside" to outpatient settings. However, it is unclear how we ensure that this shift maximises learning. The purpose of this article is to understand the authentic learning experience in an interprofessional outpatient clinic setting. We performed an exploratory case study with interviews of four nursing students, 13 medical students, and six staff members who worked in an interprofessional outpatient orthopaedic clinic from March 2015 to January 2016. The interviews were transcribed and analysed using systematic text condensation. The students' self-reported learning experience in this outpatient clinic was characterised by direct patient contact and by authentic, interprofessional, task-based learning, and a preference for indirect supervision when conducting uncomplicated patient consultations. The supervisors intended to create this interprofessional outpatient clinic experience by having a clear teaching approach based on adult learning principles in a safe and challenging learning environment. The shift to the outpatient setting was strongly and practically supported by the management. This study indicates that student learning can be shifted to the outpatient clinic setting if there is supportive management and dedicated supervisors who establish a challenging yet safe interprofessional learning environment.

  9. Comparison of dissimilarity measures for cluster analysis of X-ray diffraction data from combinatorial libraries

    NASA Astrophysics Data System (ADS)

    Iwasaki, Yuma; Kusne, A. Gilad; Takeuchi, Ichiro

    2017-12-01

    Machine learning techniques have proven invaluable to manage the ever growing volume of materials research data produced as developments continue in high-throughput materials simulation, fabrication, and characterization. In particular, machine learning techniques have been demonstrated for their utility in rapidly and automatically identifying potential composition-phase maps from structural data characterization of composition spread libraries, enabling rapid materials fabrication-structure-property analysis and functional materials discovery. A key issue in development of an automated phase-diagram determination method is the choice of dissimilarity measure, or kernel function. The desired measure reduces the impact of confounding structural data issues on analysis performance. The issues include peak height changes and peak shifting due to lattice constant change as a function of composition. In this work, we investigate the choice of dissimilarity measure in X-ray diffraction-based structure analysis and the choice of measure's performance impact on automatic composition-phase map determination. Nine dissimilarity measures are investigated for their impact in analyzing X-ray diffraction patterns for a Fe-Co-Ni ternary alloy composition spread. The cosine, Pearson correlation coefficient, and Jensen-Shannon divergence measures are shown to provide the best performance in the presence of peak height change and peak shifting (due to lattice constant change) when the magnitude of peak shifting is unknown. With prior knowledge of the maximum peak shifting, dynamic time warping in a normalized constrained mode provides the best performance. This work also serves to demonstrate a strategy for rapid analysis of a large number of X-ray diffraction patterns in general beyond data from combinatorial libraries.

  10. Components of executive functioning in metamemory.

    PubMed

    Mäntylä, Timo; Rönnlund, Michael; Kliegel, Matthias

    2010-10-01

    This study examined metamemory in relation to three basic executive functions (set shifting, working memory updating, and response inhibition) measured as latent variables. Young adults (Experiment 1) and middle-aged adults (Experiment 2) completed a set of executive functioning tasks and the Prospective and Retrospective Memory Questionnaire (PRMQ). In Experiment 1, source recall and face recognition tasks were included as indicators of objective memory performance. In both experiments, analyses of the executive functioning data yielded a two-factor solution, with the updating and inhibition tasks constituting a common factor and the shifting tasks a separate factor. Self-reported memory problems showed low predictive validity, but subjective and objective memory performance were related to different components of executive functioning. In both experiments, set shifting, but not updating and inhibition, was related to PRMQ, whereas source recall showed the opposite pattern of correlations in Experiment 1. These findings suggest that metamemorial judgments reflect selective effects of executive functioning and that individual differences in mental flexibility contribute to self-beliefs of efficacy.

  11. An automated method for mapping human tissue permittivities by MRI in hyperthermia treatment planning.

    PubMed

    Farace, P; Pontalti, R; Cristoforetti, L; Antolini, R; Scarpa, M

    1997-11-01

    This paper presents an automatic method to obtain tissue complex permittivity values to be used as input data in the computer modelling for hyperthermia treatment planning. Magnetic resonance (MR) images were acquired and the tissue water content was calculated from the signal intensity of the image pixels. The tissue water content was converted into complex permittivity values by monotonic functions based on mixture theory. To obtain a water content map by MR imaging a gradient-echo pulse sequence was used and an experimental procedure was set up to correct for relaxation and radiofrequency field inhomogeneity effects on signal intensity. Two approaches were followed to assign the permittivity values to fat-rich tissues: (i) fat-rich tissue localization by a segmentation procedure followed by assignment of tabulated permittivity values; (ii) water content evaluation by chemical shift imaging followed by permittivity calculation. Tests were performed on phantoms of known water content to establish the reliability of the proposed method. MRI data were acquired and processed pixel-by-pixel according to the outlined procedure. The signal intensity in the phantom images correlated well with water content. Experiments were performed on volunteers' healthy tissue. In particular two anatomical structures were chosen to calculate permittivity maps: the head and the thigh. The water content and electric permittivity values were obtained from the MRI data and compared to others in the literature. A good agreement was found for muscle, cerebrospinal fluid (CSF) and white and grey matter. The advantages of the reported method are discussed in the light of possible application in hyperthermia treatment planning.

  12. The integration of nonsimultaneous frequency components into a single virtual pitch.

    PubMed

    Ciocca, V; Darwin, C J

    1999-04-01

    The integration of nonsimultaneous frequency components into a single virtual pitch was investigated by using a pitch matching task in which a mistuned 4th harmonic (mistuned component) produced pitch shifts in a harmonic series (12 equal-amplitude harmonics of a 155-Hz F0). In experiment 1, the mistuned component could either be simultaneous, stop as the target started (pre-target component), or start as the target stopped (post-target component). Pitch shifts produced by the pre-target components were significantly smaller than those obtained with simultaneous components; in the post-target condition, the size of pitch shifts did not decrease relative to the simultaneous condition. In experiment 2, a silent gap of 20, 40, 80, or 160 ms was introduced between the nonsimultaneous components and the target sound. In the pre-target condition, pitch shifts were reduced to zero for silent gaps of 80 ms or longer; by contrast, a gap of 160 ms was required to eliminate pitch shifts in the post-target condition. The third experiment tested the hypothesis that, when post-target components were presented, the processing of the pitch of the target tone started at the onset of the target, and ended at the gap duration at which pitch shifts decreased to zero. This hypothesis was confirmed by the finding that pitch shifts could not be observed when the target tone had a duration of 410 ms. Taken together, the results of these experiments show that nonsimultaneous components that occur after the onset of the target sound make a larger contribution to the virtual pitch of the target, and over a longer period, than components that precede the onset of the target sound.

  13. A source mechanism producing HF-induced plasma lines (HFPLS) with up-shifted frequencies

    NASA Technical Reports Server (NTRS)

    Kuo, S. P.; Lee, M. C.

    1992-01-01

    Attention is given to a nonlinear scattering process analyzed as a source mechanism producing the frequency up-shifted HFPLs observed in the Arecibo ionospheric heating experiments. A physical picture is offered to explain how Langmuir waves with frequencies greater than the HF heater wave frequency can be produced in the heating experiments and be detected by incoherent radars as frequency up-shifted HFPLs. Since the considered scattering process occurs in a region near the reflection height, it explains why the frequency up-shifted HFPLs should originate from the altitude near the reflection height as observed. The theory also shows that the amount of frequency up-shift is inversely proportional to the frequency of the HF heater and increases linearly with the electron temperature. The quantitative analysis of the theory shows a good agreement with the experimental results.

  14. Developing Competency-Based Advising Practices in Response to Paradigm Shifts in Higher Education

    ERIC Educational Resources Information Center

    Walters, Giovanna

    2016-01-01

    Competency-based programs have gained prominence in recent years for two primary reasons. First, more students are seeking ways to apply nonclassroom learning experiences toward a degree. Second, a paradigm shift in higher education encourages postsecondary curriculum developers to accept nonclassroom experiences as demonstrations of skills and…

  15. New Teachers' Identity Shifts at the Boundary of Teacher Education and Initial Practice

    ERIC Educational Resources Information Center

    Beauchamp, Catherine; Thomas, Lynn

    2011-01-01

    As teachers enter the school communities of their initial practice, they experience identity shifts that reflect their learning. Throughout teacher education they have constructed an identity informed by their previous school experiences, the ideas and approaches promoted by their teacher education programs, and an ideal of the teachers they hope…

  16. The Instructor Experience of Fully Online Tertiary Mathematics: A Challenge and an Opportunity

    ERIC Educational Resources Information Center

    Trenholm, Sven; Alcock, Lara; Robinson, Carol

    2016-01-01

    As part of a dramatic recent shift in tertiary education, many undergraduate students now learn mathematics via fully online courses. At present, the mathematics education research community knows very little about this shift. The authors consider implications of an investigation into the instructor experience of fully online undergraduate…

  17. Bodily maps of emotions

    PubMed Central

    Nummenmaa, Lauri; Glerean, Enrico; Hari, Riitta; Hietanen, Jari K.

    2014-01-01

    Emotions are often felt in the body, and somatosensory feedback has been proposed to trigger conscious emotional experiences. Here we reveal maps of bodily sensations associated with different emotions using a unique topographical self-report method. In five experiments, participants (n = 701) were shown two silhouettes of bodies alongside emotional words, stories, movies, or facial expressions. They were asked to color the bodily regions whose activity they felt increasing or decreasing while viewing each stimulus. Different emotions were consistently associated with statistically separable bodily sensation maps across experiments. These maps were concordant across West European and East Asian samples. Statistical classifiers distinguished emotion-specific activation maps accurately, confirming independence of topographies across emotions. We propose that emotions are represented in the somatosensory system as culturally universal categorical somatotopic maps. Perception of these emotion-triggered bodily changes may play a key role in generating consciously felt emotions. PMID:24379370

  18. Targeting accuracy of single-isocenter intensity-modulated radiosurgery for multiple lesions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Calvo-Ortega, J.F., E-mail: jfcdrr@yahoo.es; Pozo, M.; Moragues, S.

    To investigate the targeting accuracy of intensity-modulated SRS (IMRS) plans designed to simultaneously treat multiple brain metastases with a single isocenter. A home-made acrylic phantom able to support a film (EBT3) in its coronal plane was used. The phantom was CT scanned and three coplanar small targets (a central and two peripheral) were outlined in the Eclipse system. Peripheral targets were 6 cm apart from the central one. A reference IMRS plan was designed to simultaneously treat the three targets, but only a single isocenter located at the center of the central target was used. After positioning the phantom onmore » the linac using the room lasers, a CBCT scan was acquired and the reference plan were mapped on it, by placing the planned isocenter at the intersection of the landmarks used in the film showing the linac isocenter. The mapped plan was then recalculated and delivered. The film dose distribution was derived using a cloud computing application ( (www.radiochromic.com)) that uses a triple-channel dosimetry algorithm. Comparison of dose distributions using the gamma index (5%/1 mm) were performed over a 5 × 5 cm{sup 2} region centered over each target. 2D shifts required to get the best gamma passing rates on the peripheral target regions were compared with the reported ones for the central target. The experiment was repeated ten times in different sessions. Average 2D shifts required to achieve optimal gamma passing rates (99%, 97%, 99%) were 0.7 mm (SD: 0.3 mm), 0.8 mm (SD: 0.4 mm) and 0.8 mm (SD: 0.3 mm), for the central and the two peripheral targets, respectively. No statistical differences (p > 0.05) were found for targeting accuracy between the central and the two peripheral targets. The study revealed a targeting accuracy within 1 mm for off-isocenter targets within 6 cm of the linac isocenter, when a single-isocenter IMRS plan is designed.« less

  19. Effectiveness of "shifting boundaries" teen dating violence prevention program for subgroups of middle school students.

    PubMed

    Taylor, Bruce G; Mumford, Elizabeth A; Stein, Nan D

    2015-02-01

    We examine whether the Shifting Boundaries (SB) intervention, a primary intervention to prevent youth dating violence and sexual harassment (DV/H), is differentially effective for girls compared with boys or for youth with a history of DV/H experiences. We randomly assigned SB to 30 public middle schools in New York City, enrolling 117 sixth and seventh grade classes to receive a classroom, building, combined, or neither intervention. The SB classroom intervention included six sessions emphasizing the laws/consequences of DV/H, establishing boundaries and safe relationships. The SB schoolwide/building intervention included the use of school-based restraining orders, greater faculty/security presence in unsafe "hot spots" mapped by students, and posters to increase DV/H awareness and reporting. Student surveys were implemented at baseline, immediately after intervention, and 6 months after intervention. At 6 months after intervention, the SB building-level intervention was associated with significant reductions in the frequency of sexual harassment (SH) perpetration and victimization; the prevalence and frequency of sexual dating violence victimization; and the frequency of total dating violence victimization and perpetration. We also had one anomalous finding that the interventions were associated with an increase in the prevalence of SH victimization. These results were consistent for girls and boys, and those with or without a history of DV/H, with the one exception for those exposed to the SB building condition who had earlier reported perpetrating SH had a significantly lower frequency of perpetrating SH at the follow-up than those without such a history. SB can provide effective universal prevention of middle school DV/H experiences, regardless of students' prior exposure histories, and for boys and girls. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  20. Electrostatic frequency maps for amide-I mode of β-peptide: Comparison of molecular mechanics force field and DFT calculations.

    PubMed

    Cai, Kaicong; Zheng, Xuan; Du, Fenfen

    2017-08-05

    The spectroscopy of amide-I vibrations has been widely utilized for the understanding of dynamical structure of polypeptides. For the modeling of amide-I spectra, two frequency maps were built for β-peptide analogue (N-ethylpropionamide, NEPA) in a number of solvents within different schemes (molecular mechanics force field based, GM map; DFT calculation based, GD map), respectively. The electrostatic potentials on the amide unit that originated from solvents and peptide backbone were correlated to the amide-I frequency shift from gas phase to solution phase during map parameterization. GM map is easier to construct with negligible computational cost since the frequency calculations for the samples are purely based on force field, while GD map utilizes sophisticated DFT calculations on the representative solute-solvent clusters and brings insight into the electronic structures of solvated NEPA and its chemical environments. The results show that the maps' predicted amide-I frequencies present solvation environmental sensitivities and exhibit their specific characters with respect to the map protocols, and the obtained vibrational parameters are in satisfactory agreement with experimental amide-I spectra of NEPA in solution phase. Although different theoretical schemes based maps have their advantages and disadvantages, the present maps show their potentials in interpreting the amide-I spectra for β-peptides, respectively. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Directional climate change and potential reversal of desertification in arid and semiarid ecosystems

    USDA-ARS?s Scientific Manuscript database

    Our objective was to determine if long-term increases in precipitation can maintain grasslands susceptible to desertification, and initiate a reversal of historic regime shifts on desertified shrublands. Long-term trends in desertification were documented using vegetation maps beginning in 1858. The...

  2. Effects of asynchrony and ear of presentation on the pitch of mistuned partials in harmonic and frequency-shifted complex tones.

    PubMed

    Brunstrom, J M; Roberts, B

    2001-07-01

    When a partial of a periodic complex is mistuned, its change in pitch is greater than expected. Two experiments examined whether these partial-pitch shifts are related to the computation of global pitch. In experiment 1, stimuli were either harmonic or frequency-shifted (25% of F0) complexes. One partial was mistuned by +/- 4% and played with leading and lagging portions of 500 ms each, relative to the other components (1 s), in both monaural and dichotic contexts. Subjects indicated whether the mistuned partial was higher or lower in pitch when concurrent with the other components. Responses were positively correlated with the direction of mistuning in all conditions. In experiment 2, stimuli from each condition were compared with synchronous equivalents. Subjects matched a pure tone to the pitch of the mistuned partial (component 4). The results showed that partial-pitch shifts are not reduced in size by asynchrony. Similar asynchronies are known to produce a near-exclusion of a mistuned partial from the global-pitch computation. This mismatch indicates that global and partial pitch are derived from different processes. The similarity of the partial-pitch shifts observed for harmonic and frequency-shifted stimuli suggests that they arise from a grouping mechanism that is sensitive to spectral regularity.

  3. Echo Mapping of Active Galactic Nuclei

    NASA Technical Reports Server (NTRS)

    Peterson, B. M.; Horne, K.

    2004-01-01

    Echo mapping makes use of the intrinsic variability of the continuum source in active galactic nuclei to map out the distribution and kinematics of line-emitting gas from its light travel time-delayed response to continuum changes. Echo mapping experiments have yielded sizes for the broad line-emitting region in about three dozen AGNs. The dynamics of the line-emitting gas seem to be dominated by the gravity of the central black hole, enabling measurement of the black-hole masses in AGNs. We discuss requirements for future echo-mapping experiments that will yield the high quality velocity-delay maps of the broad-line region that are needed to determine its physical nature.

  4. Quantitative Susceptibility Mapping: Contrast Mechanisms and Clinical Applications

    PubMed Central

    Liu, Chunlei; Wei, Hongjiang; Gong, Nan-Jie; Cronin, Matthew; Dibb, Russel; Decker, Kyle

    2016-01-01

    Quantitative susceptibility mapping (QSM) is a recently developed MRI technique for quantifying the spatial distribution of magnetic susceptibility within biological tissues. It first uses the frequency shift in the MRI signal to map the magnetic field profile within the tissue. The resulting field map is then used to determine the spatial distribution of the underlying magnetic susceptibility by solving an inverse problem. The solution is achieved by deconvolving the field map with a dipole field, under the assumption that the magnetic field is a result of the superposition of the dipole fields generated by all voxels and that each voxel has its unique magnetic susceptibility. QSM provides improved contrast to noise ratio for certain tissues and structures compared to its magnitude counterpart. More importantly, magnetic susceptibility is a direct reflection of the molecular composition and cellular architecture of the tissue. Consequently, by quantifying magnetic susceptibility, QSM is becoming a quantitative imaging approach for characterizing normal and pathological tissue properties. This article reviews the mechanism generating susceptibility contrast within tissues and some associated applications. PMID:26844301

  5. Particle visualization in high-power impulse magnetron sputtering. I. 2D density mapping

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Britun, Nikolay, E-mail: nikolay.britun@umons.ac.be; Palmucci, Maria; Konstantinidis, Stephanos

    2015-04-28

    Time-resolved characterization of an Ar-Ti high-power impulse magnetron sputtering discharge has been performed. This paper deals with two-dimensional density mapping in the discharge volume obtained by laser-induced fluorescence imaging. The time-resolved density evolution of Ti neutrals, singly ionized Ti atoms (Ti{sup +}), and Ar metastable atoms (Ar{sup met}) in the area above the sputtered cathode is mapped for the first time in this type of discharges. The energetic characteristics of the discharge species are additionally studied by Doppler-shift laser-induced fluorescence imaging. The questions related to the propagation of both the neutral and ionized discharge particles, as well as to theirmore » spatial density distributions, are discussed.« less

  6. The MAP Autonomous Mission Control System

    NASA Technical Reports Server (NTRS)

    Breed, Juile; Coyle, Steven; Blahut, Kevin; Dent, Carolyn; Shendock, Robert; Rowe, Roger

    2000-01-01

    The Microwave Anisotropy Probe (MAP) mission is the second mission in NASA's Office of Space Science low-cost, Medium-class Explorers (MIDEX) program. The Explorers Program is designed to accomplish frequent, low cost, high quality space science investigations utilizing innovative, streamlined, efficient management, design and operations approaches. The MAP spacecraft will produce an accurate full-sky map of the cosmic microwave background temperature fluctuations with high sensitivity and angular resolution. The MAP spacecraft is planned for launch in early 2001, and will be staffed by only single-shift operations. During the rest of the time the spacecraft must be operated autonomously, with personnel available only on an on-call basis. Four (4) innovations will work cooperatively to enable a significant reduction in operations costs for the MAP spacecraft. First, the use of a common ground system for Spacecraft Integration and Test (I&T) as well as Operations. Second, the use of Finite State Modeling for intelligent autonomy. Third, the integration of a graphical planning engine to drive the autonomous systems without an intermediate manual step. And fourth, the ability for distributed operations via Web and pager access.

  7. Psychosocial experiences associated with confirmed and self-identified dyslexia: a participant-driven concept map of adult perspectives.

    PubMed

    Nalavany, Blace Arthur; Carawan, Lena Williams; Rennick, Robyn A

    2011-01-01

    Concept mapping (a mixed qualitative-quantitative methodology) was used to describe and understand the psychosocial experiences of adults with confirmed and self-identified dyslexia. Using innovative processes of art and photography, Phase 1 of the study included 15 adults who participated in focus groups and in-depth interviews and were asked to elucidate their experiences with dyslexia. On index cards, 75 statements and experiences with dyslexia were recorded. The second phase of the study included 39 participants who sorted these statements into self-defined categories and rated each statement to reflect their personal experiences to produce a visual representation, or concept map, of their experience. The final concept map generated nine distinct cluster themes: Organization Skills for Success; Finding Success; A Good Support System Makes the Difference; On Being Overwhelmed; Emotional Downside; Why Can't They See It?; Pain, Hurt, and Embarrassment From Past to Present; Fear of Disclosure; and Moving Forward. Implications of these findings are discussed.

  8. Electric-acoustic pitch comparisons in single-sided-deaf cochlear implant users: frequency-place functions and rate pitch.

    PubMed

    Schatzer, Reinhold; Vermeire, Katrien; Visser, Daniel; Krenmayr, Andreas; Kals, Mathias; Voormolen, Maurits; Van de Heyning, Paul; Zierhofer, Clemens

    2014-03-01

    Eight cochlear implant users with near-normal hearing in their non-implanted ear compared pitch percepts for pulsatile electric and acoustic pure-tone stimuli presented to the two ears. Six subjects were implanted with a 31-mm MED-EL FLEX(SOFT) electrode, and two with a 24-mm medium (M) electrode, with insertion angles of the most apical contacts ranging from 565° to 758°. In the first experiment, frequency-place functions were derived from pure-tone matches to 1500-pps unmodulated pulse trains presented to individual electrodes and compared to Greenwood's frequency position map along the organ of Corti. While the overall median downward shift of the obtained frequency-place functions (-0.16 octaves re. Greenwood) and the mean shifts in the basal (<240°; -0.33 octaves) and middle (-0.35 octaves) regions were statistically significant, the shift in the apical region (>480°; 0.26 octaves) was not. Standard deviations of frequency-place functions were approximately half an octave at electrode insertion angles below 480°, increasing to an octave at higher angular locations while individual functions were gradually leveling off. In a second experiment, subjects matched the rates of unmodulated pulse trains presented to individual electrodes in the apical half of the array to low-frequency pure tones between 100 Hz and 450 Hz. The aim was to investigate the influence of electrode place on the salience of temporal pitch cues, for coding strategies that present temporal fine structure information via rate modulations on select apical channels. Most subjects achieved reliable matches to tone frequencies from 100 Hz to 300 Hz only on electrodes at angular insertion depths beyond 360°, while rate-matches to 450-Hz tones were primarily achieved on electrodes at shallower insertion angles. Only for electrodes in the second turn the average slopes of rate-pitch functions did not differ significantly from the pure-tone references, suggesting their use for the encoding of within-channel fine frequency information via rate modulations in temporal fine structure stimulation strategies. Copyright © 2013 Elsevier B.V. All rights reserved.

  9. Vibrational spectroscopy of water in hydrated lipid multi-bilayers. I. Infrared spectra and ultrafast pump-probe observables.

    PubMed

    Gruenbaum, S M; Skinner, J L

    2011-08-21

    The vibrational spectroscopy of hydration water in dilauroylphosphatidylcholine lipid multi-bilayers is investigated using molecular dynamics simulations and a mixed quantum/classical model for the OD stretch spectroscopy of dilute HDO in H(2)O. FTIR absorption spectra, and isotropic and anisotropic pump-probe decay curves have been measured experimentally as a function of the hydration level of the lipid multi-bilayer, and our goal is to make connection with these experiments. To this end, we use third-order response functions, which allow us to include non-Gaussian frequency fluctuations, non-Condon effects, molecular rotations, and a fluctuating vibrational lifetime, all of which we believe are important for this system. We calculate the response functions using existing transition frequency and dipole maps. From the experiments it appears that there are two distinct vibrational lifetimes corresponding to HDO molecules in different molecular environments. In order to obtain these lifetimes, we consider a simple two-population model for hydration water hydrogen bonds. Assuming a different lifetime for each population, we then calculate the isotropic pump-probe decay, fitting to experiment to obtain the two lifetimes for each hydration level. With these lifetimes in hand, we then calculate FTIR spectra and pump-probe anisotropy decay as a function of hydration. This approach, therefore, permits a consistent calculation of all observables within a unified computational scheme. Our theoretical results are all in qualitative agreement with experiment. The vibrational lifetime of lipid-associated OD groups is found to be systematically shorter than that of the water-associated population, and the lifetimes of each population increase with decreasing hydration, in agreement with previous analysis. Our theoretical FTIR absorption spectra successfully reproduce the experimentally observed red-shift with decreasing lipid hydration, and we confirm a previous interpretation that this shift results from the hydrogen bonding of water to the lipid phosphate group. From the pump-probe anisotropy decay, we confirm that the reorientational motions of water molecules slow significantly as hydration decreases, with water bound in the lipid carbonyl region undergoing the slowest rotations. © 2011 American Institute of Physics

  10. Vibrational spectroscopy of water in hydrated lipid multi-bilayers. I. Infrared spectra and ultrafast pump-probe observables

    PubMed Central

    Gruenbaum, S. M.; Skinner, J. L.

    2011-01-01

    The vibrational spectroscopy of hydration water in dilauroylphosphatidylcholine lipid multi-bilayers is investigated using molecular dynamics simulations and a mixed quantum∕classical model for the OD stretch spectroscopy of dilute HDO in H2O. FTIR absorption spectra, and isotropic and anisotropic pump-probe decay curves have been measured experimentally as a function of the hydration level of the lipid multi-bilayer, and our goal is to make connection with these experiments. To this end, we use third-order response functions, which allow us to include non-Gaussian frequency fluctuations, non-Condon effects, molecular rotations, and a fluctuating vibrational lifetime, all of which we believe are important for this system. We calculate the response functions using existing transition frequency and dipole maps. From the experiments it appears that there are two distinct vibrational lifetimes corresponding to HDO molecules in different molecular environments. In order to obtain these lifetimes, we consider a simple two-population model for hydration water hydrogen bonds. Assuming a different lifetime for each population, we then calculate the isotropic pump-probe decay, fitting to experiment to obtain the two lifetimes for each hydration level. With these lifetimes in hand, we then calculate FTIR spectra and pump-probe anisotropy decay as a function of hydration. This approach, therefore, permits a consistent calculation of all observables within a unified computational scheme. Our theoretical results are all in qualitative agreement with experiment. The vibrational lifetime of lipid-associated OD groups is found to be systematically shorter than that of the water-associated population, and the lifetimes of each population increase with decreasing hydration, in agreement with previous analysis. Our theoretical FTIR absorption spectra successfully reproduce the experimentally observed red-shift with decreasing lipid hydration, and we confirm a previous interpretation that this shift results from the hydrogen bonding of water to the lipid phosphate group. From the pump-probe anisotropy decay, we confirm that the reorientational motions of water molecules slow significantly as hydration decreases, with water bound in the lipid carbonyl region undergoing the slowest rotations. PMID:21861584

  11. MAPPING INDUCED POLARIZATION WITH NATURAL ELECTROMAGNETIC FIELDS FOR EXPLORATION AND RESOURCES CHARACTERIZATION BY THE MINING INDUSTRY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Edward Nichols

    2002-05-03

    In this quarter we continued the processing of the Safford IP survey data. The processing identified a time shift problem between the sites that was caused by a GPS firmware error. A software procedure was developed to identify and correct the shift, and this was applied to the data. Preliminary estimates were made of the remote referenced MT parameters, and initial data quality assessment showed the data quality was good for most of the line. The multi-site robust processing code of Egbert was linked to the new data and processing initiated.

  12. Backbone chemical shift assignments for the sensor domain of the Burkholderia pseudomallei histidine kinase RisS: "missing" resonances at the dimer interface.

    PubMed

    Buchko, Garry W; Edwards, Thomas E; Hewitt, Stephen N; Phan, Isabelle Q H; Van Voorhis, Wesley C; Miller, Samuel I; Myler, Peter J

    2015-10-01

    Using a deuterated sample, all the observable backbone (1)H(N), (15)N, (13)C(a), and (13)C' chemical shifts for the dimeric, periplasmic sensor domain of the Burkholderia pseudomallei histidine kinase RisS were assigned. Approximately one-fifth of the amide resonances are "missing" in the (1)H-(15)N HSQC spectrum and map primarily onto α-helices at the dimer interface observed in a crystal structure suggesting this region either undergoes intermediate timescale motion (μs-ms) and/or is heterogeneous.

  13. Three model space experiments on chemical reactions. [Gibbs adsorption, equilibrium shift and electrodeposition

    NASA Technical Reports Server (NTRS)

    Grodzka, P.; Facemire, B.

    1977-01-01

    Three investigations conducted aboard Skylab IV and Apollo-Soyuz involved phenomena that are of interest to the biochemistry community. The formaldehyde clock reaction and the equilibrium shift reaction experiments conducted aboard Apollo Soyuz demonstrate the effect of low-g foams or air/liquid dispersions on reaction rate and chemical equilibrium. The electrodeposition reaction experiment conducted aboard Skylab IV demonstrate the effect of a low-g environment on an electrochemical displacement reaction. The implications of the three space experiments for various applications are considered.

  14. Prior Knowledge Activation: How Different Concept Mapping Tasks Lead to Substantial Differences in Cognitive Processes, Learning Outcomes, and Perceived Self-Efficacy

    ERIC Educational Resources Information Center

    Gurlitt, Johannes; Renkl, Alexander

    2010-01-01

    Two experiments investigated the effects of characteristic features of concept mapping used for prior knowledge activation. Characteristic demands of concept mapping include connecting lines representing the relationships between concepts and labeling these lines, specifying the type of the semantic relationships. In the first experiment,…

  15. STS-59 MAPS experiment view

    NASA Technical Reports Server (NTRS)

    1994-01-01

    STS-59's MAPS (Measurement of Air Pollution from Satellites) experiment is sending real-time data that provides the most comprehensive view of carbon monoxide concentrations on Earth ever recorded. This computer image shows a summary of 'quick look' data obtained by the MAPS instrument during its first days of operations as part of the Space Shuttle Endeavour's SRL-1 payload.

  16. Experiential and Outdoor Education: The Participant Experience Shared through Mind Maps

    ERIC Educational Resources Information Center

    Jirásek, Ivo; Plevová, Irena; Jirásková, Miroslava; Dvorácková, Adéla

    2016-01-01

    This paper describes an analysis of mind maps capturing the experiences of the participants in an experiential and outdoor education course. The method of mind mapping is usually limited to a quantitative scoring analysis and comparative content analysis of concepts. As a consequence, the visual elements of the information are usually ignored, but…

  17. Retinal nerve fiber layer thickness map and blood flow pulsation measured with SDOCT

    NASA Astrophysics Data System (ADS)

    Mujat, Mircea; Chan, Raymond C.; Cense, Barry; Pierce, Mark; Park, Hyle; Joo, Chulmin; Chen, Teresa C.; de Boer, Johannes F.

    2006-02-01

    Spectral-Domain Optical Coherence Tomography (SDOCT) allows for in-vivo video-rate investigation of biomedical tissue depth structure intended for non-invasive optical diagnostics. It has been suggested that OCT can be used for di-agnosis of glaucoma by measuring the thickness of the Retinal Nerve Fiber Layer (RNLF). We present an automated method for determining the RNFL thickness from a 3-D dataset based on edge detection using a deformable spline algo-rithm. The RNFL thickness map is combined with an integrated reflectance map and retinal cross-sectional images to provide the ophthalmologist with a familiar image for interpreting the OCT data. The video-rate capabilities of our SDOCT system allow for mapping the true retinal topography since motion artifacts are significantly reduced as com-pared to slower time-domain systems. Combined with Doppler Velocimetry, SDOCT also provides information on retinal blood flow dynamics. We analyzed the pulsatile nature of the bidirectional flow dynamics in an artery-vein pair for a healthy volunteer at different locations and for different blood vessel diameters. The Doppler phase shift is determined as the phase difference at the same point of adjacent depth profiles, and is integrated over the area delimited by two circles corresponding to the blood vessels location. Its temporal evolution clearly shows the blood flow pulsatile nature, the cardiac cycle, in both artery and vein. The artery is identified as having a stronger variation of the integrated phase shift. We observe that artery pulsation is always easily detectable, while vein pulsation seems to depend on the veins diameter.

  18. Entry-Level Technical Skills that Agricultural Industry Experts Expected Students to Learn through Their Supervised Agricultural Experiences: A Modified Delphi Study

    ERIC Educational Resources Information Center

    Ramsey, Jon W.; Edwards, M. Craig

    2011-01-01

    The National Research Council's (NRC) Report (1988), Understanding Agriculture: New Directions for Education, called on secondary agricultural education to shift its scope and purpose, including students' supervised agricultural experiences (SAEs). The NRC asserted that this shift should create opportunities for students to acquire supervised…

  19. The Geospatial Web and Local Geographical Education

    ERIC Educational Resources Information Center

    Harris, Trevor M.; Rouse, L. Jesse; Bergeron, Susan J.

    2010-01-01

    Recent innovations in the Geospatial Web represent a paradigm shift in Web mapping by enabling educators to explore geography in the classroom by dynamically using a rapidly growing suite of impressive online geospatial tools. Coupled with access to spatial data repositories and User-Generated Content, the Geospatial Web provides a powerful…

  20. Fluctuations in Value: The Shifting Worth of Journal Articles in Educational Administration

    ERIC Educational Resources Information Center

    Eacott, Scott

    2018-01-01

    Journal rankings are increasingly being used as proxies for assessing the quality and worth of individual faculty and their contribution to institutional performance. Problematic within this agenda is the historical mapping and projection of current journal rankings. Individual papers are being assessed against criteria far…

  1. Old Lamps for New: Mnemonic Techniques and the Thesis

    ERIC Educational Resources Information Center

    Carter, Susan

    2009-01-01

    The mnemonic techniques of the past, like mind maps, metaphors, and narrative theory, offer research students, especially doctoral candidates, another cognitive support. These techniques pre-date computers (and possibly literacy), so shift cognitive organization from the page or the computer screen to the mind. This article compares early memory…

  2. Putting Growth and Value-Added Models on the Map: A National Overview

    ERIC Educational Resources Information Center

    Collins, Clarin; Amrein-Beardsley, Audrey

    2014-01-01

    Background: Within the last few years, the focus on educational accountability has shifted from holding students responsible for their own performance to holding those shown to impact student performance responsible--students' teachers. Encouraged and financially incentivized by federal programs, states are becoming ever more reliant on…

  3. 30 CFR 75.1505 - Escapeway maps.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY... or the miners' work stations to the surface or the exits at the bottom of the shaft or slope, refuge... made. (c) Informing affected miners. Miners underground on a shift when any such change is made shall...

  4. The Political Geography of Europe: 1900-2000 A.D.

    ERIC Educational Resources Information Center

    Blouet, Brian W.

    1996-01-01

    Traces the often chaotic restructuring of European national boundaries from before World War I to after the collapse of the Soviet Union. Offers a concise and interesting overview of the political, economic, and military events that shaped modern Europe. Includes seven detailed maps showing shifting boundaries and alliances. (MJP)

  5. Mapping Literacy-Rich Environments: Geospatial Perspectives on Literacy and Education

    ERIC Educational Resources Information Center

    Jocson, Korina M.; Thorne-Wallington, Elizabeth

    2013-01-01

    Background: Literacy-rich environments (LREs) reflect characteristics such as abundance of materials, daily literacy routine, and layout conducive for reading and writing. Shifting from previous conceptualizations, LREs are not confined to schools but are ubiquitous in formal and informal educational settings; they include libraries, museums,…

  6. Navigating the Digital Shift: Mapping the Acquisition of Digital Instructional Materials

    ERIC Educational Resources Information Center

    Fox, Christine; Jones, Rachel; Neugent, Lan

    2015-01-01

    In 2015, the State Educational Technology Directors Association (SETDA) administered the Digital Instructional Materials Survey regarding state policies and guidelines for the acquisition, vetting, and funding of instructional resources for all 50 states, Guam, and the Commonwealth of Northern Mariana Islands (CNMI). Based upon this survey,…

  7. Shifting Interests: Changes in the Lexical Semantics of ED-MEDIA

    ERIC Educational Resources Information Center

    Wild, Fridolin; Valentine, Chris; Scott, Peter

    2010-01-01

    Large research networks naturally form complex communities with overlapping but not identical expertise. To map the distribution of professional competence in field of "technology-enhanced learning", the lexical semantics expressed in research articles published in a representative, large-scale conference (ED-MEDIA) can be investigated and changes…

  8. Short-term Memory as a Processing Shift

    ERIC Educational Resources Information Center

    Lewis-Smith, Marion Quinn

    1975-01-01

    The series of experiments described here examined the predictions for free recall from sequential models and the shift formulation, focusing on the roles of short- and long-term memory in the primacy/recency shift and on the effects of expectancies on short- and long-term memory. (Author/RK)

  9. Direct magnetic field estimation based on echo planar raw data.

    PubMed

    Testud, Frederik; Splitthoff, Daniel Nicolas; Speck, Oliver; Hennig, Jürgen; Zaitsev, Maxim

    2010-07-01

    Gradient recalled echo echo planar imaging is widely used in functional magnetic resonance imaging. The fast data acquisition is, however, very sensitive to field inhomogeneities which manifest themselves as artifacts in the images. Typically used correction methods have the common deficit that the data for the correction are acquired only once at the beginning of the experiment, assuming the field inhomogeneity distribution B(0) does not change over the course of the experiment. In this paper, methods to extract the magnetic field distribution from the acquired k-space data or from the reconstructed phase image of a gradient echo planar sequence are compared and extended. A common derivation for the presented approaches provides a solid theoretical basis, enables a fair comparison and demonstrates the equivalence of the k-space and the image phase based approaches. The image phase analysis is extended here to calculate the local gradient in the readout direction and improvements are introduced to the echo shift analysis, referred to here as "k-space filtering analysis." The described methods are compared to experimentally acquired B(0) maps in phantoms and in vivo. The k-space filtering analysis presented in this work demonstrated to be the most sensitive method to detect field inhomogeneities.

  10. Isolation and Characterization of Chromosome-Gain and Increase-in-Ploidy Mutants in Yeast

    PubMed Central

    Chan, CSM.; Botstein, D.

    1993-01-01

    We have developed a colony papillation assay for monitoring the copy number of genetically marked chromosomes II and III in Saccharomyces cerevisiae. The unique feature of this assay is that it allows detection of a gain of the marked chromosomes even if there is a gain of the entire set of chromosomes (increase-in-ploidy). This assay was used to screen for chromosome-gain or increase-in-ploidy mutants. Five complementation groups have been defined for recessive mutations that confer an increase-in-ploidy (ipl) phenotype, which, in each case, cosegregates with a temperature-sensitive growth phenotype. Four new alleles of CDC31, which is required for spindle pole body duplication, were also recovered from this screen. Temperature-shift experiments with ipl1 cells show that they suffer severe nondisjunction at 37°. Similar experiments with ipl2 cells show that they gain entire sets of chromosomes and become arrested as unbudded cells at 37°. Molecular cloning and genetic mapping show that IPL1 is a newly identified gene, whereas IPL2 is allelic to BEM2, which is required for normal bud growth. PMID:8293973

  11. GPs' experiences with out-of-hours GP cooperatives: a survey study from the Netherlands.

    PubMed

    Smits, Marleen; Keizer, Ellen; Huibers, Linda; Giesen, Paul

    2014-09-01

    Out-of-hours primary care has been provided by general practitioner (GP) cooperatives since the year 2000 in the Netherlands. Early studies in countries with similar organizational structures showed positive GP experiences. However, nowadays it is said that GPs experience a high workload at the cooperative and that they outsource a considerable part of their shifts. To examine positive and negative experiences of GPs providing out-of-hours primary care, and the frequency and reasons for outsourcing shifts. A cross-sectional observational survey among 688 GPs connected to six GP cooperatives in the Netherlands, using a web-based questionnaire. The response was 55% (n = 378). The main reasons for working in GP cooperatives were to retain registration as GP (79%) and remain experienced in acute care (74%). GPs considered the peak hours (81%) and the high number of patients (73%) as the most negative aspects. Most GPs chose to provide the out-of-hours shifts themselves: 85% outsourced maximally 25% of their shifts. The percentage of outsourced shifts increased with age. Main reasons for outsourcing were the desire to have more private time (76%); the high workload in daytime practice (71%); and less the workload during out-of-hours (46%). GPs are motivated to work in out-of-hours GP cooperatives, and they outsource few shifts. GPs consider the peak load and the large number of (non-urgent) help requests as the most negative aspects. To motivate and involve GPs for 7 × 24-h primary care, it is important to set limits on their workload.

  12. Defining functional biomes and monitoring their change globally.

    PubMed

    Higgins, Steven I; Buitenwerf, Robert; Moncrieff, Glenn R

    2016-11-01

    Biomes are important constructs for organizing understanding of how the worlds' major terrestrial ecosystems differ from one another and for monitoring change in these ecosystems. Yet existing biome classification schemes have been criticized for being overly subjective and for explicitly or implicitly invoking climate. We propose a new biome map and classification scheme that uses information on (i) an index of vegetation productivity, (ii) whether the minimum of vegetation activity is in the driest or coldest part of the year, and (iii) vegetation height. Although biomes produced on the basis of this classification show a strong spatial coherence, they show little congruence with existing biome classification schemes. Our biome map provides an alternative classification scheme for comparing the biogeochemical rates of terrestrial ecosystems. We use this new biome classification scheme to analyse the patterns of biome change observed over recent decades. Overall, 13% to 14% of analysed pixels shifted in biome state over the 30-year study period. A wide range of biome transitions were observed. For example, biomes with tall vegetation and minimum vegetation activity in the cold season shifted to higher productivity biome states. Biomes with short vegetation and low seasonality shifted to seasonally moisture-limited biome states. Our findings and method provide a new source of data for rigorously monitoring global vegetation change, analysing drivers of vegetation change and for benchmarking models of terrestrial ecosystem function. © 2016 John Wiley & Sons Ltd.

  13. A pronounced evolutionary shift of the pseudoautosomal region boundary in house mice

    PubMed Central

    White, Michael A.; Ikeda, Akihiro; Payseur, Bret A.

    2012-01-01

    The pseudoautosomal region (PAR) is essential for the accurate pairing and segregation of the X and Y chromosomes during meiosis. Despite its functional significance, the PAR shows substantial evolutionary divergence in structure and sequence between mammalian species. An instructive example of PAR evolution is the house mouse Mus musculus domesticus (represented by the C57BL/6J strain), which has the smallest PAR among those that have been mapped. In C57BL/6J, the PAR boundary is located just ~700 kb from the distal end of the X chromosome, whereas the boundary is found at a more proximal position in Mus spretus, a species that diverged from house mice 2–4 million years ago. Here, we use a combination of genetic and physical mapping to document a pronounced shift in the PAR boundary in a second house mouse subspecies, Mus musculus castaneus (represented by the CAST/EiJ strain), ~430 kb proximal of the M. m. domesticus boundary. We demonstrate molecular evolutionary consequences of this shift, including a marked lineage-specific increase in sequence divergence within Mid1, a gene that resides entirely within the M. m. castaneus PAR but straddles the boundary in other subspecies. Our results extend observations of structural divergence in the PAR to closely related subspecies, pointing to major evolutionary changes in this functionally important genomic region over a short time period. PMID:22763584

  14. A pronounced evolutionary shift of the pseudoautosomal region boundary in house mice.

    PubMed

    White, Michael A; Ikeda, Akihiro; Payseur, Bret A

    2012-08-01

    The pseudoautosomal region (PAR) is essential for the accurate pairing and segregation of the X and Y chromosomes during meiosis. Despite its functional significance, the PAR shows substantial evolutionary divergence in structure and sequence between mammalian species. An instructive example of PAR evolution is the house mouse Mus musculus domesticus (represented by the C57BL/6J strain), which has the smallest PAR among those that have been mapped. In C57BL/6J, the PAR boundary is located just ~700 kb from the distal end of the X chromosome, whereas the boundary is found at a more proximal position in Mus spretus, a species that diverged from house mice 2-4 million years ago. In this study we used a combination of genetic and physical mapping to document a pronounced shift in the PAR boundary in a second house mouse subspecies, Mus musculus castaneus (represented by the CAST/EiJ strain), ~430 kb proximal of the M. m. domesticus boundary. We demonstrate molecular evolutionary consequences of this shift, including a marked lineage-specific increase in sequence divergence within Mid1, a gene that resides entirely within the M. m. castaneus PAR but straddles the boundary in other subspecies. Our results extend observations of structural divergence in the PAR to closely related subspecies, pointing to major evolutionary changes in this functionally important genomic region over a short time period.

  15. Discomfort analysis in computerized numeric control machine operations.

    PubMed

    Muthukumar, Krishnamoorthy; Sankaranarayanasamy, Krishnasamy; Ganguli, Anindya Kumar

    2012-06-01

    The introduction of computerized numeric control (CNC) technology in manufacturing industries has revolutionized the production process, but there are some health and safety problems associated with these machines. The present study aimed to investigate the extent of postural discomfort in CNC machine operators, and the relationship of this discomfort to the display and control panel height, with a view to validate the anthropometric recommendation for the location of the display and control panel in CNC machines. The postural discomforts associated with CNC machines were studied in 122 male operators using Corlett and Bishop's body part discomfort mapping, subject information, and discomfort level at various time intervals from starting to end of a shift. This information was collected using a questionnaire. Statistical analysis was carried out using ANOVA. Neck discomfort due to the positioning of the machine displays, and shoulder and arm discomfort due to the positioning of controls were identified as common health issues in the operators of these machines. The study revealed that 45.9% of machine operators reported discomfort in the lower back, 41.8% in the neck, 22.1% in the upper-back, 53.3% in the shoulder and arm, and 21.3% of the operators reported discomfort in the leg. Discomfort increased with the progress of the day and was highest at the end of a shift; subject age had no effect on patient tendency to experience discomfort levels.

  16. Promoter mapping of the mouse Tcp-10bt gene in transgenic mice identifies essential male germ cell regulatory sequences.

    PubMed

    Ewulonu, U K; Snyder, L; Silver, L M; Schimenti, J C

    1996-03-01

    Transgenic mice were generated to localize essential promoter elements in the mouse testis-expressed Tcp-10 genes. These genes are expressed exclusively in male germ cells, and exhibit a diffuse range of transcriptional start sites, possibly due to the absence of a TATA box. A series of transgene constructs containing different amounts of 5' flanking DNA revealed that all sequences necessary for appropriate temporal and tissue-specific transcription of Tcp-10 reside between positions -1 to -973. All transgenic animals containing these sequences expressed a chimeric transgene at high levels, in a pattern that paralleled the endogenous genes. These experiments further defined a 227 bp fragment from -746 to -973 that was absolutely essential for expression. In a gel-shift assay, this 227-bp fragment bound nuclear protein from testis, but not other tissues, to yield two retarded bands. Sequence analysis of this fragment revealed a half-site for the AP-2 transcription factor recognition sequence. Gel shift assays using native or mutant oligonucleotides demonstrated that the putative AP-2 recognition sequence was essential for generating the retarded bands. Since the binding activity is testis-specific, but AP-2 expression is not exclusive to male germ cells, it is possible that transcription of Tcp-10 requires interaction between AP-2 and a germ cell-specific transcription factor.

  17. Discomfort Analysis in Computerized Numeric Control Machine Operations

    PubMed Central

    Sankaranarayanasamy, Krishnasamy; Ganguli, Anindya Kumar

    2012-01-01

    Objectives The introduction of computerized numeric control (CNC) technology in manufacturing industries has revolutionized the production process, but there are some health and safety problems associated with these machines. The present study aimed to investigate the extent of postural discomfort in CNC machine operators, and the relationship of this discomfort to the display and control panel height, with a view to validate the anthropometric recommendation for the location of the display and control panel in CNC machines. Methods The postural discomforts associated with CNC machines were studied in 122 male operators using Corlett and Bishop's body part discomfort mapping, subject information, and discomfort level at various time intervals from starting to end of a shift. This information was collected using a questionnaire. Statistical analysis was carried out using ANOVA. Results Neck discomfort due to the positioning of the machine displays, and shoulder and arm discomfort due to the positioning of controls were identified as common health issues in the operators of these machines. The study revealed that 45.9% of machine operators reported discomfort in the lower back, 41.8% in the neck, 22.1% in the upper-back, 53.3% in the shoulder and arm, and 21.3% of the operators reported discomfort in the leg. Conclusion Discomfort increased with the progress of the day and was highest at the end of a shift; subject age had no effect on patient tendency to experience discomfort levels. PMID:22993720

  18. The NMR contribution to protein-protein networking in Fe-S protein maturation.

    PubMed

    Banci, Lucia; Camponeschi, Francesca; Ciofi-Baffoni, Simone; Piccioli, Mario

    2018-03-22

    Iron-sulfur proteins were among the first class of metalloproteins that were actively studied using NMR spectroscopy tailored to paramagnetic systems. The hyperfine shifts, their temperature dependencies and the relaxation rates of nuclei of cluster-bound residues are an efficient fingerprint of the nature and the oxidation state of the Fe-S cluster. NMR significantly contributed to the analysis of the magnetic coupling patterns and to the understanding of the electronic structure occurring in [2Fe-2S], [3Fe-4S] and [4Fe-4S] clusters bound to proteins. After the first NMR structure of a paramagnetic protein was obtained for the reduced E. halophila HiPIP I, many NMR structures were determined for several Fe-S proteins in different oxidation states. It was found that differences in chemical shifts, in patterns of unobserved residues, in internal mobility and in thermodynamic stability are suitable data to map subtle changes between the two different oxidation states of the protein. Recently, the interaction networks responsible for maturing human mitochondrial and cytosolic Fe-S proteins have been largely characterized by combining solution NMR standard experiments with those tailored to paramagnetic systems. We show here the contribution of solution NMR in providing a detailed molecular view of "Fe-S interactomics". This contribution was particularly effective when protein-protein interactions are weak and transient, and thus difficult to be characterized at high resolution with other methodologies.

  19. Transfer of an implied incompatible spatial mapping to a Simon task.

    PubMed

    Luo, Chunming; Proctor, Robert W

    2016-02-01

    When location words left and right are presented in left and right locations and mapped to left and right keypress responses in the Hedge and Marsh (1975) task (Arend & Wandmacher, 1987), a compatible mapping of words to responses yields a benefit for stimulus-response location correspondence (sometimes called the Simon effect), whereas an incompatible mapping yields a benefit for noncorrespondence (called the Hedge and Marsh reversal). Experiment 1 replicated the correspondence benefit and its reversal by using Chinese location words [symbol: see text] (left) and [symbol: see text] (right) in the Hedge and Marsh task. Experiments 2 and 3 examined whether the tendency to respond with the noncorresponding response when the mapping is incompatible transfers to the task version in which the mapping is compatible, and Experiment 4 examined whether transfer similarly occurs from the compatible mapping to the task version with incompatible mapping. Transfer of the incompatible relation was apparent in a lack of correspondence benefit when the mapping was changed to compatible, but transfer of the compatible relation to the incompatible mapping did not occur. The results suggest that an association between noncorresponding stimulus-response locations is acquired when the word-response mapping is incompatible, even though this relation is only implicit, regardless of whether through misapplication of a logical recoding rule or spatial representations shared by the locations and words. These associations then continue to affect processing of location when the mapping is compatible. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. 3D mapping of turbulence: a laboratory experiment

    NASA Astrophysics Data System (ADS)

    Le Louarn, Miska; Dainty, Christopher; Paterson, Carl; Tallon, Michel

    2000-07-01

    In this paper, we present the first experimental results of the 3D mapping method. 3D mapping of turbulence is a method to remove the cone effect with multiple laser guide stars and multiple deformable mirrors. A laboratory experiment was realized to verify the theoretical predictions. The setup consisted of two turbulent phase screens (made with liquid crystal devices) and a Shack-Hartmann wavefront sensor. We describe the interaction matrix involved in reconstructing Zernike commands for multiple deformable mirror from the slope measurements made from laser guide stars. It is shown that mirror commands can indeed be reconstructed with the 3D mapping method. Limiting factors of the method, brought to light by this experiment are discussed.

  1. Mapping experiment with space station

    NASA Technical Reports Server (NTRS)

    Wu, S. S. C.

    1986-01-01

    Mapping of the Earth from space stations can be approached in two areas. One is to collect gravity data for defining topographic datum using Earth's gravity field in terms of spherical harmonics. The other is to search and explore techniques of mapping topography using either optical or radar images with or without reference to ground central points. Without ground control points, an integrated camera system can be designed. With ground control points, the position of the space station (camera station) can be precisely determined at any instant. Therefore, terrestrial topography can be precisely mapped either by conventional photogrammetric methods or by current digital technology of image correlation. For the mapping experiment, it is proposed to establish four ground points either in North America or Africa (including the Sahara desert). If this experiment should be successfully accomplished, it may also be applied to the defense charting systems.

  2. (3, 2)D 1H, 13C BIRDr,X-HSQC-TOCSY for NMR structure elucidation of mixtures: application to complex carbohydrates.

    PubMed

    Brodaczewska, Natalia; Košťálová, Zuzana; Uhrín, Dušan

    2018-02-01

    Overlap of NMR signals is the major cause of difficulties associated with NMR structure elucidation of molecules contained in complex mixtures. A 2D homonuclear correlation spectroscopy in particular suffers from low dispersion of 1 H chemical shifts; larger dispersion of 13 C chemical shifts is often used to reduce this overlap, while still providing the proton-proton correlation information e.g. in the form of a 2D 1 H, 13 C HSQC-TOCSY experiment. For this methodology to work, 13 C chemical shift must be resolved. In case of 13 C chemical shifts overlap, 1 H chemical shifts can be used to achieve the desired resolution. The proposed (3, 2)D 1 H, 13 C BIRD r,X -HSQC-TOCSY experiment achieves this while preserving singlet character of cross peaks in the F 1 dimension. The required high-resolution in the 13 C dimension is thus retained, while the cross peak overlap occurring in a regular HSQC-TOCSY experiment is eliminated. The method is illustrated on the analysis of a complex carbohydrate mixture obtained by depolymerisation of a fucosylated chondroitin sulfate isolated from the body wall of the sea cucumber Holothuria forskali.

  3. Systematic Review and Meta-analysis of the Effects of Caffeine in Fatigued Shift Workers: Implications for Emergency Medical Services Personnel

    DOT National Transportation Integrated Search

    2018-01-11

    Background: Emergency Medical Services (EMS) workers may experience fatigue as a consequence of shift work. We reviewed the literature to determine the impact of caffeine as a countermeasure to fatigue in EMS personnel and related shift workers. Meth...

  4. Investigation of high power impulse magnetron sputtering (HIPIMS) discharge using fast ICCD camera

    NASA Astrophysics Data System (ADS)

    Hecimovic, Ante

    2012-10-01

    High power impulse magnetron sputtering (HIPIMS) combines impulse glow discharges at power levels up to the MW range with conventional magnetron cathodes to achieve a highly ionised sputtered flux. The dynamics of the HIPIMS discharge was investigated using fast Intensified Charge Coupled Device (ICCD) camera. In the first experiment the HIPIMS plasma was recorded from the side with goal to analyse the plasma intensity using Abel inversion to obtain the emissivity maps of the plasma species. Resulting emissivity maps provide the information on the spatial distribution of Ar and sputtered material and evolution of the plasma chemistry above the cathode. In the second experiment the plasma emission was recorded with camera facing the target. The images show that the HIPIMS plasma develops drift wave type instabilities characterized by well defined regions of high and low plasma emissivity along the racetrack of the magnetron. The instabilities cause periodic shifts in the floating potential. The structures rotate in ExB direction at velocities of 10 kms-1 and frequencies up to 200 kHz. The high emissivity regions comprise Ar and metal ion emission with strong Ar and metal neutral emission depletion. A detailed analysis of the temporal evolution of the saturated instabilities using four consequently triggered fast ICCD cameras is presented. Furthermore working gas pressure and discharge current variation showed that the shape and the speed of the instability strongly depend on the working gas and target material combination. In order to better understand the mechanism of the instability, different optical interference band pass filters (of metal and gas atom, and ion lines) were used to observe the spatial distribution of each species within the instability.

  5. The experience of being a shift-leader in a hospital ward.

    PubMed

    Goldblatt, Hadass; Granot, Michal; Admi, Hanna; Drach-Zahavy, Anat

    2008-07-01

    This paper is a report of a study to explore the experience of being a shift-leader, and how these nurses view the management of their shift. Professional demands on skilled and capable shift-leaders, who competently handle multi-disciplinary staff and patients, as well as operations and information, call for the development of efficient nursing leadership roles. Nevertheless, knowledge of shift-leaders' perspectives concerning their task management and leadership styles is relatively limited. Twenty-eight Registered Nurses working in an Israeli medical centre participated in this qualitative study. Data were gathered through in-depth interviews conducted in two phases between February and October 2005: three focus group interviews (phase 1) followed by seven individual interviews (phase 2). Content analysis revealed two major themes which constitute the essence of being a shift-leader: (1) a burden of responsibility, where the shift-leader moves between positions of maximum control and delegating some responsibility to other nurses; (2) the role's temporal dimension, expressed as a strong desire to reach the end of the shift safely, and taking managerial perspectives beyond the boundaries of the specific shift. The core of the shift-leader's position is an immense sense of responsibility. However, this managerial role is transient and therefore lacks an established authority. A two-dimensional taxonomy of these themes reveals four types of potential and actual coping among shift-leaders, indicating the need to train them in leadership skills and systemic thinking. Interventions to limit the potential stress hazards should be focused simultaneously on shift-leaders themselves and on job restructuring.

  6. Searching for cosmic strings in CMB anisotropy maps using wavelets and curvelets

    NASA Astrophysics Data System (ADS)

    Hergt, Lukas; Amara, Adam; Brandenberger, Robert; Kacprzak, Tomasz; Réfrégier, Alexandre

    2017-06-01

    We use wavelet and curvelet transforms to extract signals of cosmic strings from simulated cosmic microwave background (CMB) temperature anisotropy maps, and to study the limits on the cosmic string tension which various ongoing CMB temperature anisotropy experiments will be able to achieve. We construct sky maps with size and angular resolution corresponding to various experiments. These maps contain the signals of a scaling solution of long string segments with a given string tension G μ, the contribution of the dominant Gaussian primordial cosmological fluctuations, and pixel by pixel white noise with an amplitude corresponding to the instrumental noise of the various experiments. In the case that we include white noise, we find that using curvelets we obtain lower bounds on the string tension than with wavelets. For maps with Planck specification, we obtain bounds comparable to what was obtained by the Planck collaboration [1]. Experiments with better angular resolution such as the South Pole Telescope third generation (SPT-3G) survey will be able to yield stronger limits. For maps with a specification of SPT-3G we find that string signals will be visible down to a string tension of G μ = 1.4 × 10-7.

  7. Posture Affects How Robots and Infants Map Words to Objects

    PubMed Central

    Morse, Anthony F.; Benitez, Viridian L.; Belpaeme, Tony; Cangelosi, Angelo; Smith, Linda B.

    2015-01-01

    For infants, the first problem in learning a word is to map the word to its referent; a second problem is to remember that mapping when the word and/or referent are again encountered. Recent infant studies suggest that spatial location plays a key role in how infants solve both problems. Here we provide a new theoretical model and new empirical evidence on how the body – and its momentary posture – may be central to these processes. The present study uses a name-object mapping task in which names are either encountered in the absence of their target (experiments 1–3, 6 & 7), or when their target is present but in a location previously associated with a foil (experiments 4, 5, 8 & 9). A humanoid robot model (experiments 1–5) is used to instantiate and test the hypothesis that body-centric spatial location, and thus the bodies’ momentary posture, is used to centrally bind the multimodal features of heard names and visual objects. The robot model is shown to replicate existing infant data and then to generate novel predictions, which are tested in new infant studies (experiments 6–9). Despite spatial location being task-irrelevant in this second set of experiments, infants use body-centric spatial contingency over temporal contingency to map the name to object. Both infants and the robot remember the name-object mapping even in new spatial locations. However, the robot model shows how this memory can emerge –not from separating bodily information from the word-object mapping as proposed in previous models of the role of space in word-object mapping – but through the body’s momentary disposition in space. PMID:25785834

  8. Functional Equivalence of Spatial Images from Touch and Vision: Evidence from Spatial Updating in Blind and Sighted Individuals

    PubMed Central

    Giudice, Nicholas A.; Betty, Maryann R.; Loomis, Jack M.

    2012-01-01

    This research examines whether visual and haptic map learning yield functionally equivalent spatial images in working memory, as evidenced by similar encoding bias and updating performance. In three experiments, participants learned four-point routes either by seeing or feeling the maps. At test, blindfolded participants made spatial judgments about the maps from imagined perspectives that were either aligned or misaligned with the maps as represented in working memory. Results from Experiments 1 and 2 revealed a highly similar pattern of latencies and errors between visual and haptic conditions. These findings extend the well known alignment biases for visual map learning to haptic map learning, provide further evidence of haptic updating, and most importantly, show that learning from the two modalities yields very similar performance across all conditions. Experiment 3 found the same encoding biases and updating performance with blind individuals, demonstrating that functional equivalence cannot be due to visual recoding and is consistent with an amodal hypothesis of spatial images. PMID:21299331

  9. On the Mechanism for a Gravity Effect Using Type 2 Superconductors

    NASA Technical Reports Server (NTRS)

    Robertson, Glen A.

    1999-01-01

    In this paper, we formulate a percent mass change equation based on Woodward's transient mass shift and the Cavendish balance equations applied to superconductor Josephson junctions, A correction to the transient mass shift equation is presented due to the emission of the mass energy from the superconductor. The percentage of mass change predicted by the equation was estimated against the maximum percent mass change reported by Podkletnov in his gravity shielding experiments. An experiment is then discussed, which could shed light on the transient mass shift near superconductor and verify the corrected gravitational potential.

  10. Effects of Phonological and Orthographic Shifts on Children's Processing of Written Morphology: A Time-Course Study

    ERIC Educational Resources Information Center

    Quémart, Pauline; Casalis, Séverine

    2014-01-01

    We report two experiments that investigated whether phonological and/or orthographic shifts in a base word interfere with morphological processing by French 3rd, 4th, and 5th graders and adults (as a control group) along the time course of visual word recognition. In both experiments, prime-target pairs shared four possible relationships:…

  11. Effect of a Surprising Downward Shift in Reinforcer Value on Stimulus Over-Selectivity in a Simultaneous Discrimination Procedure

    ERIC Educational Resources Information Center

    Reynolds, Gemma; Reed, Phil

    2013-01-01

    Stimulus over-selectivity refers to the phenomenon whereby behavior is controlled by a subset of elements in the environment at the expense of other equally salient aspects of the environment. The experiments explored whether this cue interference effect was reduced following a surprising downward shift in reinforcer value. Experiment 1 revealed…

  12. Heavy NP shift is the parser’s last resort: Evidence from eye movements ⋆

    PubMed Central

    Staub, Adrian; Clifton, Charles; Frazier, Lyn

    2006-01-01

    Two eye movement experiments explored the roles of verbal subcategorization possibilities and transitivity biases in the processing of heavy NP shift sentences in which the verb’s direct object appears to the right of a post-verbal phrase. In Experiment 1, participants read sentences in which a prepositional phrase immediately followed the verb, which was either obligatorily transitive or had a high transitivity bias (e.g., Jack praised/watched from the stands his daughter’s attempt to shoot a basket). Experiment 2 compared unshifted sentences to sentences in which an adverb intervened between the verb and its object, and obligatorily transitive verbs to optionally transitive verbs with widely varying transitivity biases. In both experiments, evidence of processing difficulty appeared on the material that intervened between the verb and its object when the verb was obligatorily transitive, and on the shifted direct object when the verb was optionally transitive, regardless of transitivity bias. We conclude that the parser adopts the heavy NP shift analysis only when it is forced to by the grammar, which we interpret in terms of a preference for immediate incremental interpretation. PMID:17047731

  13. Detection of metal stress in boreal forest species using the 0.67-micron chlorophyll absorption band

    NASA Technical Reports Server (NTRS)

    Singhroy, Vernon H.; Kruse, Fred A.

    1991-01-01

    Several recent studies have shown that a shift of the red-edge inflection near 0.70 micron in vegetation reflectance spectra is an indicator of metal stress, partially attributable to changes in chlorophyll concentration. This 'red-edge shift', however, is difficult to detect and has been reported both toward longer (red) and shorter (blue) wavelengths. Our work demonstrates that direct measurement of the depth and width of the chlorophyll absorption band at 0.67 micron using digital feature extraction and absorption band characterization procedures developed for the analysis of mineral spectra is a more consistent indicator of metal stress. Additionally, the magnitude of these parameters is generally greater than that of the red edge shift and thus should be more amenable to detection and mapping using field and aircraft spectrometers.

  14. California State Waters Map Series: offshore of San Francisco, California

    USGS Publications Warehouse

    Cochrane, Guy R.; Johnson, Samuel Y.; Dartnell, Peter; Greene, H. Gary; Erdey, Mercedes D.; Golden, Nadine E.; Hartwell, Stephen R.; Endris, Charles A.; Manson, Michael W.; Sliter, Ray W.; Kvitek, Rikk G.; Watt, Janet Tilden; Ross, Stephanie L.; Bruns, Terry R.; Cochrane, Guy R.; Cochran, Susan A.

    2015-01-01

    Circulation over the continental shelf in the Offshore of San Francisco map area is dominated by the southward-flowing California Current, an eastern limb of the North Pacific Gyre that flows from Oregon to Baja California. At its midpoint offshore of central California, the California Current transports subarctic surface waters southeastward, about 150 to 1,300 km from shore. Seasonal northwesterly winds that are, in part, responsible for the California Current, generate coastal upwelling. Ocean temperatures offshore of central California have increased over the past 50 years, driving an ecosystem shift from the productive subarctic regime towards a depopulated subtropical environment.

  15. Damage mapping in structural health monitoring using a multi-grid architecture

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mathews, V. John

    2015-03-31

    This paper presents a multi-grid architecture for tomography-based damage mapping of composite aerospace structures. The system employs an array of piezo-electric transducers bonded on the structure. Each transducer may be used as an actuator as well as a sensor. The structure is excited sequentially using the actuators and the guided waves arriving at the sensors in response to the excitations are recorded for further analysis. The sensor signals are compared to their baseline counterparts and a damage index is computed for each actuator-sensor pair. These damage indices are then used as inputs to the tomographic reconstruction system. Preliminary damage mapsmore » are reconstructed on multiple coordinate grids defined on the structure. These grids are shifted versions of each other where the shift is a fraction of the spatial sampling interval associated with each grid. These preliminary damage maps are then combined to provide a reconstruction that is more robust to measurement noise in the sensor signals and the ill-conditioned problem formulation for single-grid algorithms. Experimental results on a composite structure with complexity that is representative of aerospace structures included in the paper demonstrate that for sufficiently high sensor densities, the algorithm of this paper is capable of providing damage detection and characterization with accuracy comparable to traditional C-scan and A-scan-based ultrasound non-destructive inspection systems quickly and without human supervision.« less

  16. NMR Mapping of Protein Conformational Landscapes using Coordinated Behavior of Chemical Shifts upon Ligand Binding

    PubMed Central

    Cembran, Alessandro; Kim, Jonggul; Gao, Jiali; Veglia, Gianluigi

    2014-01-01

    Proteins exist as an ensemble of conformers that are distributed on free energy landscapes resembling folding funnels. While the most stable conformers populate low energy basins, protein function is often carried out through low-populated conformational states that occupy high energy basins. Ligand binding shifts the populations of these states, changing the distribution of these conformers. Understanding how the equilibrium among the states is altered upon ligand binding, interaction with other binding partners, and/or mutations and post-translational modifications is of critical importance for explaining allosteric signaling in proteins. Here, we propose a statistical analysis of the chemical shifts (CONCISE, COordiNated ChemIcal Shifts bEhavior) for the interpretation of protein conformational equilibria following linear trajectories of NMR chemical shifts. CONCISE enables one to quantitatively measure the population shifts associated with ligand titrations and estimate the degree of collectiveness of the protein residues’ response to ligand binding, giving a concise view of the structural transitions. The combination of CONCISE with thermocalorimetric and kinetic data allows one to depict a protein’s approximate conformational energy landscape. We tested this method with the catalytic subunit of cAMP-dependent protein kinase A, a ubiquitous enzyme that undergoes conformational transitions upon both nucleotide and pseudo-substrate binding. When complemented with chemical shift covariance analysis (CHESCA), this new method offers both collective response and residue-specific correlations for ligand binding to proteins. PMID:24604024

  17. Adaptation to shift work: physiologically based modeling of the effects of lighting and shifts' start time.

    PubMed

    Postnova, Svetlana; Robinson, Peter A; Postnov, Dmitry D

    2013-01-01

    Shift work has become an integral part of our life with almost 20% of the population being involved in different shift schedules in developed countries. However, the atypical work times, especially the night shifts, are associated with reduced quality and quantity of sleep that leads to increase of sleepiness often culminating in accidents. It has been demonstrated that shift workers' sleepiness can be improved by a proper scheduling of light exposure and optimizing shifts timing. Here, an integrated physiologically-based model of sleep-wake cycles is used to predict adaptation to shift work in different light conditions and for different shift start times for a schedule of four consecutive days of work. The integrated model combines a model of the ascending arousal system in the brain that controls the sleep-wake switch and a human circadian pacemaker model. To validate the application of the integrated model and demonstrate its utility, its dynamics are adjusted to achieve a fit to published experimental results showing adaptation of night shift workers (n = 8) in conditions of either bright or regular lighting. Further, the model is used to predict the shift workers' adaptation to the same shift schedule, but for conditions not considered in the experiment. The model demonstrates that the intensity of shift light can be reduced fourfold from that used in the experiment and still produce good adaptation to night work. The model predicts that sleepiness of the workers during night shifts on a protocol with either bright or regular lighting can be significantly improved by starting the shift earlier in the night, e.g.; at 21:00 instead of 00:00. Finally, the study predicts that people of the same chronotype, i.e. with identical sleep times in normal conditions, can have drastically different responses to shift work depending on their intrinsic circadian and homeostatic parameters.

  18. The relationship between quality of sleep and night shift rotation interval.

    PubMed

    Kim, Jae Youn; Chae, Chang Ho; Kim, Young Ouk; Son, Jun Seok; Kim, Ja Hyun; Kim, Chan Woo; Park, Hyoung Ouk; Lee, Jun Ho; Kwon, Soon Il; Kwon, Sun Il

    2015-01-01

    Shift work is closely related with workers' health. In particular, sleep is thought to be affected by shift work. In addition, shift work has been reported to be associated with the type or direction of shift rotation, number of consecutive night shifts, and number of off-duty days. We aimed to analyze the association between the night shift rotation interval and the quality of sleep reported by Korean female shift workers. In total, 2,818 female shift workers from the manufacturing industry who received an employee physical examination at a single university hospital from January to August in 2014 were included. Subjects were classified into three groups (A, B, and C) by their night shift rotation interval. The quality of sleep was measured using the Korean version of the Pittsburgh Sleep Quality Index (PSQI). Descriptive analysis, univariate logistic regression, and multivariate logistic regression were performed. With group A as the reference, the odds ratio (OR) for having a seriously low quality of sleep was 1.456 (95% CI 1.171-1.811) and 2.348 (95% CI 1.852-2.977) for groups B and C, respectively. Thus, group C with the shortest night shift rotation interval was most likely to have a low quality of sleep. After adjustment for age, obesity, smoking status, alcohol consumption, exercise, being allowed to sleep during night shifts, work experience, and shift work experience, groups B and C had ORs of 1.419 (95% CI 1.134-1.777) and 2.238 (95% CI 1.737-2.882), respectively, compared to group A. Our data suggest that a shorter night shift rotation interval does not provide enough recovery time to adjust the circadian rhythm, resulting in a low quality of sleep. Because shift work is influenced by many different factors, future studies should aim to determine the most optimal shift work model and collect accurate, prospective data.

  19. Genetic characterization of frameshift suppressors with new decoding properties.

    PubMed Central

    Hughes, D; Thompson, S; O'Connor, M; Tuohy, T; Nichols, B P; Atkins, J F

    1989-01-01

    Suppressor mutants that cause ribosomes to shift reading frame at specific and new sequences are described. Suppressors for trpE91, the only known suppressible -1 frameshift mutant, have been isolated in Escherichia coli and in Salmonella typhimurium. E. coli hopR acts on trpE91 within the 9-base-pair sequence GGA GUG UGA, is dominant, and is located at min 52 on the chromosome. Its Salmonella homolog maps at an equivalent position and arises as a rarer class in that organism as compared with E. coli. The Salmonella suppressor, hopE, believed to be in a duplicate copy of the same gene, maps at min 17. The +1 suppressor, sufT, acts at the nonmonotonous sequence CCGU, is dominant, and maps at min 59 on the Salmonella chromosome. PMID:2644219

  20. Constant-time 2D and 3D through-bond correlation NMR spectroscopy of solids under 60 kHz MAS

    PubMed Central

    Zhang, Rongchun; Ramamoorthy, Ayyalusamy

    2016-01-01

    Establishing connectivity and proximity of nuclei is an important step in elucidating the structure and dynamics of molecules in solids using magic angle spinning (MAS) NMR spectroscopy. Although recent studies have successfully demonstrated the feasibility of proton-detected multidimensional solid-state NMR experiments under ultrafast-MAS frequencies and obtaining high-resolution spectral lines of protons, assignment of proton resonances is a major challenge. In this study, we first re-visit and demonstrate the feasibility of 2D constant-time uniform-sign cross-peak correlation (CTUC-COSY) NMR experiment on rigid solids under ultrafast-MAS conditions, where the sensitivity of the experiment is enhanced by the reduced spin-spin relaxation rate and the use of low radio-frequency power for heteronuclear decoupling during the evolution intervals of the pulse sequence. In addition, we experimentally demonstrate the performance of a proton-detected pulse sequence to obtain a 3D 1H/13C/1H chemical shift correlation spectrum by incorporating an additional cross-polarization period in the CTUC-COSY pulse sequence to enable proton chemical shift evolution and proton detection in the incrementable t1 and t3 periods, respectively. In addition to through-space and through-bond 13C/1H and 13C/13C chemical shift correlations, the 3D 1H/13C/1H experiment also provides a COSY-type 1H/1H chemical shift correlation spectrum, where only the chemical shifts of those protons, which are bonded to two neighboring carbons, are correlated. By extracting 2D F1/F3 slices (1H/1H chemical shift correlation spectrum) at different 13C chemical shift frequencies from the 3D 1H/13C/1H spectrum, resonances of proton atoms located close to a specific carbon atom can be identified. Overall, the through-bond and through-space homonuclear/heteronuclear proximities determined from the 3D 1H/13C/1H experiment would be useful to study the structure and dynamics of a variety of chemical and biological solids. PMID:26801026

  1. Map Sensitivity vs. Map Dependency: A Case Study of Subway Maps’ Impact on Passenger Route Choices in Washington DC

    PubMed Central

    Xu, John

    2017-01-01

    This paper addresses the key assumption in behavioral and transportation planning literature that, when people use a transit system more frequently, they become less dependent on and less sensitive to transit maps in their decision-making. Therefore, according to this assumption, map changes are much less impactful to travel decisions of frequent riders than to that of first-time or new passengers. This assumption—though never empirically validated—has been the major hurdle for transit maps to becoming a planning tool to change passengers’ behavior. This paper examines this assumption using the Washington DC metro map as a case study by conducting a route choice experiment between 30 Origin-Destination (O-D) pairs on seven metro map designs. The experiment targets two types of passengers: frequent metro riders through advertisements on a free daily newspaper available at DC metro stations, and general residents in the Washington metropolitan area through Amazon Mechanical Turk, an online crowdsourcing platform. A total of 255 and 371 participants made 2024 and 2960 route choices in the respective experiments. The results show that frequent passengers are in fact more sensitive to subtle changes in map design than general residents who are less likely to be familiar with the metro map and therefore unaffected by map changes presented in the alternative designs. The work disproves the aforementioned assumption and further validates metro maps as an effective planning tool in transit systems. PMID:29068371

  2. 2J, 3J-HMBC: A New Long-Range Heteronuclear Shift Correlation Technique Capable of Differentiating 2JCH from 3JCH Correlations to Protonated Carbons

    NASA Astrophysics Data System (ADS)

    Krishnamurthy, V. V.; Russell, David J.; Hadden, Chad E.; Martin, Gary E.

    2000-09-01

    The development of a series of new, accordion-optimized long-range heteronuclear shift correlation techniques has been reported. A further derivative of the constant time variable delay introduced in the IMPEACH-MBC experiment, a STAR (Selectively Tailored Accordion F1 Refocusing) operator is described in the present report. Incorporation of the STAR operator with the capability of user-selected homonuclear modulation scaling as in the CIGAR-HMBC experiment, into a long-range heteronuclear shift correlation pulse sequence, 2J,3J-HMBC, affords for the first time in a proton-detected experiment the means of unequivocally differentiating two-bond (2JCH) from three-bond (3JCH) long-range correlations to protonated carbons.

  3. Restructuring Student Experiences Using Tech Prep Mapping To Integrate Vocational and Academic Curriculum.

    ERIC Educational Resources Information Center

    Pirozzoli, Don

    The growing emphasis on accountability and the demand for better prepared students is pressing institutions of higher education to examine restructuring. Student experiences represent an important arena for school restructuring, and a useful approach to changing student experiences is the Tech Prep Mapping (TPM) process. The TPM process requires…

  4. Application of Ifsar Technology in Topographic Mapping: JUPEM's Experience

    NASA Astrophysics Data System (ADS)

    Zakaria, Ahamad

    2018-05-01

    The application of Interferometric Synthetic Aperture Radar (IFSAR) in topographic mapping has increased during the past decades. This is due to the advantages that IFSAR technology offers in solving data acquisition problems in tropical regions. Unlike aerial photography, radar technology offers wave penetration through cloud cover, fog and haze. As a consequence, images can be made free of any natural phenomenon defects. In Malaysia, Department of Survey and Mapping Malaysia (JUPEM) has been utilizing the IFSAR products since 2009 to update topographic maps at 1 : 50,000 map scales. Orthorectified radar imagery (ORI), Digital Surface Models (DSM) and Digital Terrain Models (DTM) procured under the project have been further processed before the products are ingested into a revamped mapping workflow consisting of stereo and mono digitizing processes. The paper will highlight the experience of Department of Survey and Mapping Malaysia (DSMM)/ JUPEM in using such technology in order to speed up mapping production.

  5. In search of the motor engram: motor map plasticity as a mechanism for encoding motor experience.

    PubMed

    Monfils, Marie-H; Plautz, Erik J; Kleim, Jeffrey A

    2005-10-01

    Motor skill acquisition occurs through modification and organization of muscle synergies into effective movement sequences. The learning process is reflected neurophysiologically as a reorganization of movement representations within the primary motor cortex, suggesting that the motor map is a motor engram. However, the specific neural mechanisms underlying map plasticity are unknown. Here the authors review evidence that 1) motor map topography reflects the capacity for skilled movement, 2) motor skill learning induces reorganization of motor maps in a manner that reflects the kinematics of acquired skilled movement, 3) map plasticity is supported by a reorganization of cortical microcircuitry involving changes in synaptic efficacy, and 4) motor map integrity and topography are influenced by various neurochemical signals that coordinate changes in cortical circuitry to encode motor experience. Finally, the role of motor map plasticity in recovery of motor function after brain damage is discussed.

  6. Coping strategies and social support needs of experienced and inexperienced nurses performing shiftwork.

    PubMed

    Gifkins, Jane; Loudoun, Rebecca; Johnston, Amy

    2017-12-01

    The aim of this investigation was to compare perceptions of nurses exposed to short or longer term shift work and their experiences working under this type of scheduling. Shift work is a crucial component of nurses' working lives, ensuring continuous care for patients. This study fills a research gap around the personal experiences of shift working nurses and the strategies used to manage the impacts of shift work. Qualitative case study design. Constructivist methodology, including in-depth semi-structured interviews conducted in 2015, was used for the study. Iterative review and inductive analysis of transcripts from nine recently graduated nurses and twelve experienced nurses enabled identification and verification of key themes. Three main areas of difference between new and experienced nurses relating to shift work challenges in a nursing environment emerged: perceptions about the utility of working in shifts, coping strategies and social support at home and work. Most experienced nurses found shift work advantageous, especially those with dependents. Coping strategies included flexible shift arrangements in both groups. Experienced nurses detailed the importance of support from family and friends while inexperienced nurses described feeling disconnected from social supports. Experienced nurses cited a lack of support from nursing managers as problematic. Findings suggest shift selection mitigated challenges of shift work for both inexperienced and experienced nurses, indicating autonomous roster selection is critical. Similarly, social support at work from senior nurses and management and at home played an important role in nurses' coping. © 2017 John Wiley & Sons Ltd.

  7. JIGSAW: Joint Inhomogeneity estimation via Global Segment Assembly for Water-fat separation.

    PubMed

    Lu, Wenmiao; Lu, Yi

    2011-07-01

    Water-fat separation in magnetic resonance imaging (MRI) is of great clinical importance, and the key to uniform water-fat separation lies in field map estimation. This work deals with three-point field map estimation, in which water and fat are modelled as two single-peak spectral lines, and field inhomogeneities shift the spectrum by an unknown amount. Due to the simplified spectrum modelling, there exists inherent ambiguity in forming field maps from multiple locally feasible field map values at each pixel. To resolve such ambiguity, spatial smoothness of field maps has been incorporated as a constraint of an optimization problem. However, there are two issues: the optimization problem is computationally intractable and even when it is solved exactly, it does not always separate water and fat images. Hence, robust field map estimation remains challenging in many clinically important imaging scenarios. This paper proposes a novel field map estimation technique called JIGSAW. It extends a loopy belief propagation (BP) algorithm to obtain an approximate solution to the optimization problem. The solution produces locally smooth segments and avoids error propagation associated with greedy methods. The locally smooth segments are then assembled into a globally consistent field map by exploiting the periodicity of the feasible field map values. In vivo results demonstrate that JIGSAW outperforms existing techniques and produces correct water-fat separation in challenging imaging scenarios.

  8. Experiments Using Cell Phones in Physics Classroom Education: The Computer-Aided g Determination

    NASA Astrophysics Data System (ADS)

    Vogt, Patrik; Kuhn, Jochen; Müller, Sebastian

    2011-09-01

    This paper continues the collection of experiments that describe the use of cell phones as experimental tools in physics classroom education.1-4 We describe a computer-aided determination of the free-fall acceleration g using the acoustical Doppler effect. The Doppler shift is a function of the speed of the source. Since a free-falling objects speed is changing linearly with time, the Doppler shift is also changing with time. It is possible to measure this shift using software that is both easy to use and readily available. Students will use the time-dependency of the Doppler shift to experimentally determine the acceleration due to gravity by using a cell phone as a freely falling object emitting a sound with constant frequency.

  9. Influence of rate of change of frequency on the overall pitch of frequency-modulated tones.

    PubMed

    Gockel, H; Moore, B C; Carlyon, R P

    2001-02-01

    The mechanism(s) determining pitch may assign less weight to portions of a sound where the frequency is changing rapidly. The present experiments explored the possible effect of this on the overall pitch of frequency-modulated sounds. Pitch matches were obtained between an adjustable unmodulated sinusoid and a sinusoidal carrier that was frequency modulated using a highly asymmetric function with the form of a repeating U or inverted U shaped function. The amplitude was constant during the 400-ms presentation time of each stimulus, except for 10-ms raised-cosine onset and offset ramps. In experiment 1, the carrier level was 50 dB SPL and the geometric mean of the instantaneous frequency of the modulated carrier, fc, was either 0.5, 1, 2, or 8 kHz. The modulation rate (fm) was 5, 10, or 20 Hz. The overall depth (maximum to minimum) of the FM was 8% of fc. For all carrier frequencies, the matched frequency was shifted away from the mean carrier frequency, downwards for the U shaped function stimuli and upwards for the repeated inverted U shaped function stimuli. The shift was typically slightly greater than 1% of fc, and did not vary markedly with fc. The effect of fm was small, but there was a trend for the shifts to decrease with increasing fm for fc = 0.5 kHz and to increase with increasing fm for fc = 2 kHz. In experiment 2, the carrier level was reduced to 20 dB SL and matches were obtained only for fc = 2 kHz. Shifts in matched frequency of about 1% were still observed, but the trend for the shifts to increase with increasing fm no longer occurred. In experiment 3, matches were obtained for a 4-kHz carrier at 50 dB SPL. Shifts of about 1% again occurred, which did not vary markedly with fm. The shifts in matched frequency observed in all three experiments are not predicted by models based on the amplitude- or intensity-weighted average of instantaneous frequency (EWAIF or IWAIF). The shifts (and the pitch shifts observed earlier for two-tone complexes and for stimuli with simultaneous AM and FM) are consistent with a model based on the assumption that the overall pitch of a frequency-modulated sound is determined from a weighted average of period estimates, with the weight attached to a given estimate being inversely related to the short-term rate of change of period and directly related to a compressive function of the amplitude.

  10. Neural correlates of set-shifting in children with autism

    PubMed Central

    Yerys, Benjamin E.; Antezana, Ligia; Weinblatt, Rachel; Jankowski, Kathryn F.; Strang, John; Vaidya, Chandan J.; Schultz, Robert T.; Gaillard, William D.; Kenworthy, Lauren

    2015-01-01

    Autism spectrum disorder (ASD) is often associated with high levels of inflexible thinking and rigid behavior. The neural correlates of these behaviors have been investigated in adults and older adolescents, but not children. Prior studies utilized set-shifting tasks that engaged multiple levels of shifting, and depended on learning abstract rules and establishing a strong prepotent bias. These additional demands complicate simple interpretations of the results. We used functional magnetic resonance imaging (fMRI) to investigate the neural correlates of set-shifting in 20 children (ages 7-14) with ASD and 19 typically developing, matched, control children. Participants completed a set-shifting task that minimized non-shifting task demands through the use of concrete instructions that provide spatial mapping of stimuli-responses. The shift/stay sets were given an equal number of trials to limit the prepotent bias. Both groups showed an equivalent ‘switch cost’, responding less accurately and slower to Switch stimuli than Stay stimuli, although the ASD group was less accurate overall. Both groups showed activation in prefrontal, striatal, parietal, and cerebellum regions known to govern effective set-shifts. Compared to controls, children with ASD demonstrated decreased activation of the right middle temporal gyrus across all trials, but increased activation in the mid-dorsal cingulate cortex/superior frontal gyrus, left middle frontal and right inferior frontal gyri during the Switch vs. Stay contrast. The successful behavioral switching performance of children with ASD comes at the cost of requiring greater engagement of frontal regions, suggesting less efficiency at this lowest level of shifting. PMID:25599972

  11. Sources of Cognitive Inflexibility in Set-Shifting Tasks: Insights into Developmental Theories from Adult Data

    ERIC Educational Resources Information Center

    Dick, Anthony Steven

    2012-01-01

    Two experiments examined processes underlying cognitive inflexibility in set-shifting tasks typically used to assess the development of executive function in children. Adult participants performed a Flexible Item Selection Task (FIST) that requires shifting from categorizing by one dimension (e.g., color) to categorizing by a second orthogonal…

  12. Physiological and behavioral effects of tilt-induced body fluid shifts

    NASA Technical Reports Server (NTRS)

    Parker, D. E.; Tjernstrom, O.; Ivarsson, A.; Gulledge, W. L.; Poston, R. L.

    1983-01-01

    This paper addresses the 'fluid shift theory' of space motion sickness. The primary purpose of the research was the development of procedures to assess individual differences in response to rostral body fluid shifts on earth. Experiment I examined inner ear fluid pressure changes during head-down tilt in intact human beings. Tilt produced reliable changes. Differences among subjects and between ears within the same subject were observed. Experiment II examined auditory threshold changes during tilt. Tilt elicited increased auditory thresholds, suggesting that sensory depression may result from increased inner ear fluid pressure. Additional observations on rotation magnitude estimation during head-down tilt, which indicate that rostral fluid shifts may depress semicircular canal activity, are briefly described. The results of this research suggest that the inner ear pressure and auditory threshold shift procedures could be used to assess individual differences among astronauts prior to space flight. Results from the terrestrial observations could be related to reported incidence/severity of motion sickness in space and used to evaluate the fluid shift theory of space motion sickness.

  13. Impact of 12h shift patterns in nursing: a scoping review.

    PubMed

    Harris, Ruth; Sims, Sarah; Parr, Jenny; Davies, Nigel

    2015-02-01

    To provide a comprehensive scoping review of evidence of the impact and effectiveness of 12h shifts in the international nursing literature, supplemented by a review of evidence in other, non-nursing related industries. A search of the academic literature was undertaken in electronic databases (AMED, MEDLINE, CINAHL, PsychInfo, Scopus, HMIC, the Cochrane Library, Business Source Premier, Econ Lit, ASSIA and Social Policy and Practice). A total of 158 potentially relevant nursing research papers and reviews were published between 1973 and 2014. Two reviewers independently reviewed the articles, leaving 85 primary research studies and 10 review papers in the nursing field to be included in the scoping review. Thirty-one relevant primary research papers and reviews were also identified in the non-nursing related industries literature. Research into 12h nursing shifts fell within five broad themes: 'risks to patients', 'patient experience', 'risks to staff', 'staff experience' and 'impact on the organisation of work'. There was inconclusive evidence of the effects of 12h shift patterns in all five themes, with some studies demonstrating positive impacts and others negative or no impacts. This also mirrors the evidence in other, non-nursing related industries. The quality of research reviewed is generally weak and most studies focus on the risks, experience and work/life balance for staff, with few addressing the impact on patient outcomes and experience of care or work productivity. There is insufficient evidence to justify the widespread implementation or withdrawal of 12h shifts in nursing. It is not clearly understood where there are real benefits and where there are real and unacceptable risks to patients and staff. More research focusing on the impact of 12h nursing shifts on patient safety and experience of care and on the long term impact on staff and work organisation is required. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. USGS standard quadrangle maps for emergency response

    USGS Publications Warehouse

    Moore, Laurence R.

    2009-01-01

    The 1:24,000-scale topographic quadrangle was the primary product of the U.S. Geological Survey's (USGS) National Mapping Program from 1947-1992. This map series includes about 54,000 map sheets for the conterminous United States, and is the only uniform map series ever produced that covers this area at such a large scale. This map series partially was revised under several programs, starting as early as 1968, but these programs were not adequate to keep the series current. Through the 1990s the emphasis of the USGS mapping program shifted away from topographic maps and toward more specialized digital data products. Topographic map revision dropped off rapidly after 1999, and stopped completely by 2004. Since 2001, emergency-response and homeland security requirement have revived the question of whether a standard national topographic series is needed. Emergencies such as Hurricane Katrina in 2005 and California wildfires in 2007-08 demonstrated that familiar maps are important to first responders. Maps that have a standard scale, extent, and grids help reduce confusion and save time in emergencies. Traditional maps are designed to allow the human brain to quickly process large amounts of information, and depend on artistic layout and design that cannot be fully automated. In spite of technical advances, creating a traditional, general-purpose topographic map is still expensive. Although the content and layout of traditional topographic maps probably is still desirable, the preferred packaging and delivery of maps has changed. Digital image files are now desired by most users, but to be useful to the emergency-response community, these files must be easy to view and easy to print without specialized geographic information system expertise or software.

  15. Influence of night-shift and napping at work on urinary melatonin, 17-β-estradiol and clock gene expression in pre-menopausal nurses.

    PubMed

    Bracci, M; Copertaro, A; Manzella, N; Staffolani, S; Strafella, E; Nocchi, L; Barbaresi, M; Copertaro, B; Rapisarda, V; Valentino, M; Santarelli, L

    2013-01-01

    Night-workers experience disruption of the sleep-wake cycle and light at night which may increase breast cancer risk by suppressing the nocturnal melatonin surge, resulting in higher levels of circulating estrogens. Night-work may also deregulate peripheral clock genes which have been found to be altered in breast cancer. This study investigated urinary 6-sulfatoxymelatonin (aMT6s), serum 17-beta-estradiol levels in premenopausal shift nurses at the end of the night-shift compared to a control group of daytime nurses. Peripheral clock gene expression in lymphocytes were also investigated. All participants were sampled in the follicular phase of the menstrual cycle. The effect of nurses’ ability to take a short nap during the night-shift was also explored. The shift-work group had significantly lower aMT6s levels than daytime nurses independently of a nap. Night-shift napping significantly influences 17-beta-estradiol levels resulting in higher outcomes in nurses who do not take a nap compared to napping group and daytime workers. Peripheral clock genes expression investigated was not significantly different among the groups. Our findings suggest that shift nurses experience changes in aMT6s levels after a night-shift. Napping habits influence 17-beta-estradiol levels at the end of a night-shift. These findings might be related to the increased cancer risk reported in night-shift workers and suggest that a short nap during night-shifts may exert a positive effect.

  16. Designing a Futuristic Business Studies Curriculum

    ERIC Educational Resources Information Center

    Mei, Chiew Wye; Siraj, Saedah

    2013-01-01

    This paper is a discourse on the theoretical aspects underpinning the design of the Business Studies curriculum domain. It draws on recent shifts in the business and educational environment of Malaysia, and maps out the methodology and method for expanding and revamping the core ground of the discipline. Using the pragmatic worldview stance, this…

  17. Number Line Estimation in Children with Developmental Dyscalculia

    ERIC Educational Resources Information Center

    Sella, Francesco; Berteletti, Ilaria; Martina, Brazzolotto; Lucangeli, Daniela; Zorzi, Marco

    2013-01-01

    In the number to position task, several studies have shown that typically developing children shift from a biased (logarithmic) to an accurate (linear) mapping of symbolic digits onto a spatial position on a line. The initial pattern of overestimation of small numbers and the underestimation of larger numbers is compensated by means of age and…

  18. Mapping Language Ideologies in Multi-Ethnic Urban Europe: The Case of Parisian French

    ERIC Educational Resources Information Center

    Stewart, Christopher Michael

    2012-01-01

    Although the modern multicultural European metropolis has brought previously disparate groups into close contact, little research has focused on the effect of these shifting demographic patterns on language attitudes and ideologies. This is probably due to the sensitive nature of issues relating to immigration which may evoke contexts of…

  19. Divergent cellular responses during asymptomatic subclinical and clinical states of disease in cows naturally infected with Mycobacterium avium subsp. paratuberculosis

    USDA-ARS?s Scientific Manuscript database

    Infection of the host with Mycobacterium avium subsp. paratuberculosis (MAP) results in a chronic and progressive enteritis that traverses both subclinical and clinical stages. The mechanism(s) for the shift from asymptomatic subclinical disease state to advanced clinical disease are not fully under...

  20. Secure and Resilient Cloud Computing for the Department of Defense

    DTIC Science & Technology

    2015-11-16

    platform as a service (PaaS), and software as a service ( SaaS )—that target system administrators, developers, and end-users respectively (see Table 2...interfaces (API) and services Medium Amazon Elastic MapReduce, MathWorks Cloud, Red Hat OpenShift SaaS Full-fledged applications Low Google gMail

  1. Textural analysis of historical aerial photography to characterize woody plant encroachment in South African savanna

    Treesearch

    Andrew T. Hudak; Carol A. Wessman

    1998-01-01

    Transitions from grassland to shrubland through woody plant encroachment result in potentially significant shifts in savanna ecosystem function. Given high resolution imagery, a textural index could prove useful for mapping woody plant densities and monitoring woody plant encroachment across savanna landscapes. Spatial heterogeneity introduced through mixtures of...

  2. Research Methodologies Explored for a Paradigm Shift in University Teaching.

    ERIC Educational Resources Information Center

    Venter, I. M.; Blignaut, R. J.; Stoltz, D.

    2001-01-01

    Innovative teaching methods such as collaborative learning, teamwork, and mind maps were introduced to teach computer science and statistics courses at a South African university. Soft systems methodology was adapted and used to manage the research process of evaluating the effectiveness of the teaching methods. This research method provided proof…

  3. 75 FR 27992 - Solicitation of Applications for the Research and Evaluation Program: FY 2010 Mapping Regional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... goods, labor and knowledge. These transformations warrant dramatic shifts in the role of economic... development activities, or a consortium of political subdivisions; an institution of higher education or a consortium of institutions of higher education; and a public or private non-profit organization or...

  4. Glacier fluctuation using Satellite Data in Beas basin, 1972-2006, Himachal Pradesh, India

    NASA Astrophysics Data System (ADS)

    Dutta, Shruti; Ramanathan, A. L.; Linda, Anurag

    2012-10-01

    Glaciers are widely recognized as sensitive indicators for regional climate change. Very few studies have been conducted to investigate the long term deglaciation status in the Himalaya. In the present study, glaciers in the Beas basin, Himachal Pradesh, India were mapped by interpretation of various glacio-morphological features using the Landsat and IRS images. The mapping of 224 glaciers during the period 1972-2006 reveals that the glacier cover reduced from 419 to 371 km2, witnessing approximately 11.6% deglaciation in the Beas basin. A higher rate of retreat of the glaciers was observed during 1989-2006 as compared to the retreat during 1972-1989. Also, the loss has been more prominent in the glaciers with an areal extent of 2-5 km2. The number of glaciers increased from 224 to 236 due to fragmentation in this period. The average elevation of the ablation zone basin showed an upward shift from 3898 m (1972) to 4171 m (2006) which may be a consequence of a shift in Equilibrium Line Altitude (ELA) reflecting imbalance.

  5. Determination of the mean inner potential of cadmium telluride via electron holography

    NASA Astrophysics Data System (ADS)

    Cassidy, C.; Dhar, A.; Shintake, T.

    2017-04-01

    Mean inner potential is a fundamental material parameter in solid state physics and electron microscopy and has been experimentally measured in CdTe, a technologically important semiconductor. As a first step, the inelastic mean free path for electron scattering in CdTe was determined, using electron energy loss spectroscopy, to enable precise thickness mapping of thin CdTe lamellae. The obtained value was λi(CdTe, 300 kV) = 192 ± 10 nm. This value is relatively large, given the high density of the material, and is discussed in the text. Next, electron diffraction and specimen tilting were employed to identify weakly diffracting lattice orientations, to enable the straightforward measurement of the electron phase shift. Finally, electron holography was utilized to quantitatively map the phase shift experienced by electron waves passing through a CdTe crystal, with several different propagation vectors. Utilization of both thickness and phase data allowed computation of mean inner potential as V0 (CdTe) = 14.0 ± 0.9 V, within the range of previous theoretical estimates.

  6. Benzoate-mediated changes on expression profile of soluble proteins in Serratia sp. DS001.

    PubMed

    Pandeeti, E V P; Chinnaboina, M R; Siddavattam, D

    2009-05-01

    To assess differences in protein expression profile associated with shift in carbon source from succinate to benzoate in Serratia sp. DS001 using a proteomics approach. A basic proteome map was generated for the soluble proteins extracted from Serratia sp. DS001 grown in succinate and benzoate. The differently and differentially expressed proteins were identified using ImageMaster 2D Platinum software (GE Healthcare). The identity of the proteins was determined by employing MS or MS/MS. Important enzymes such as Catechol 1,2 dioxygenase and transcriptional regulators that belong to the LysR superfamily were identified. Nearly 70 proteins were found to be differentially expressed when benzoate was used as carbon source. Based on the protein identity and degradation products generated from benzoate it is found that ortho pathway is operational in Serratia sp. DS001. Expression profile of the soluble proteins associated with shift in carbon source was mapped. The study also elucidates degradation pathway of benzoate in Serratia sp. DS001 by correlating the proteomics data with the catabolites of benzoate.

  7. Conflict escalation in paediatric services: findings from a qualitative study.

    PubMed

    Forbat, Liz; Teuten, Bea; Barclay, Sarah

    2015-08-01

    To explore clinician and family experiences of conflict in paediatric services, in order to map the trajectory of conflict escalation. Qualitative interview study, employing extreme-case sampling. Interviews were analysed using an iterative thematic approach to identify common themes regarding the experience and escalation of conflict. Thirty-eight health professionals and eight parents. All participants had direct experience of conflict, including physical assault and court proceedings, at the interface of acute and palliative care. Two teaching hospitals, one district general hospital and two paediatric hospices in England, in 2011. Conflicts escalate in a predictable manner. Clearly identifiable behaviours by both clinicians and parents are defined as mild, moderate and severe. Mild describes features like the insensitive use of language and a history of unresolved conflict. Moderate involves a deterioration of trust, and a breakdown of communication and relationships. Severe marks disintegration of working relationships, characterised by behavioural changes including aggression, and a shift in focus from the child's best interests to the conflict itself. Though conflicts may remain at one level, those which escalated tended to move sequentially from one level to the next. Understanding how conflicts escalate provides clinicians with a practical, evidence-based framework to identify the warning signs of conflict in paediatrics. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  8. CE: Original Research: Napping on the Night Shift: A Two-Hospital Implementation Project.

    PubMed

    Geiger-Brown, Jeanne; Sagherian, Knar; Zhu, Shijun; Wieroniey, Margaret Ann; Blair, Lori; Warren, Joan; Hinds, Pamela S; Szeles, Rose

    2016-05-01

    : Nurses who work the night shift often experience high levels of sleepiness. Napping has been adopted as an effective countermeasure to sleepiness and fatigue in other safety-sensitive industries, but has not had widespread acceptance in nursing. To assess the barriers to successful implementation of night-shift naps and to describe the nap experiences of night-shift nurses who took naps. In this two-hospital pilot implementation project, napping on the night shift was offered to six nursing units for which the executive nursing leadership had given approval. Unit nurse managers' approval was sought, and where granted, further explanation was given to the unit's staff nurses. A nap experience form, which included the Karolinska Sleepiness Scale, was used to assess pre-nap sleepiness level, nap duration and perceived sleep experience, post-nap sleep inertia, and the perceived helpfulness of the nap. Nurse managers and staff nurses were also interviewed at the end of the three-month study period. Successful implementation occurred on only one of the six units, with partial success seen on a second unit. Barriers primarily occurred at the point of seeking the unit nurse managers' approval. On the successful unit, 153 30-minutes naps were taken during the study period. A high level of sleepiness was present at the beginning of 44% of the naps. For more than half the naps, nurses reported achieving either light (43%) or deep (14%) sleep. Sleep inertia was rare. The average score of helpfulness of napping was high (7.3 on a 1-to-10 scale). Nurses who napped reported being less drowsy while driving home after their shift. These data suggest that when barriers to napping are overcome, napping on the night shift is feasible and can reduce nurses' workplace sleepiness and drowsy driving on the way home. Addressing nurse managers' perceptions of and concerns about napping may be essential to successful implementation.

  9. Single-shot Z(eff) dense plasma diagnostic through simultaneous refraction and attenuation measurements with a Talbot-Lau x-ray moiré deflectometer.

    PubMed

    Valdivia, M P; Stutman, D; Finkenthal, M

    2015-04-01

    The Talbot-Lau x-ray moiré deflectometer is a powerful plasma diagnostic capable of delivering simultaneous refraction and attenuation information through the accurate detection of x-ray phase shift and intensity. The diagnostic can provide the index of refraction n=1-δ+iβ of an object (dense plasma, for example) placed in the x-ray beam by independently measuring both δ and β, which are directly related to the electron density n(e) and the attenuation coefficient μ, respectively. Since δ and β depend on the effective atomic number Z(eff), a map can be obtained from the ratio between phase and absorption images acquired in a single shot. The Talbot-Lau x-ray moiré deflectometer and its corresponding data acquisition and processing are briefly described to illustrate how the above is achieved; Z(eff) values of test objects within the 4-12 range were obtained experimentally through simultaneous refraction and attenuation measurements. We show that Z(eff) mapping of objects does not require previous knowledge of sample length or shape. The determination of Z(eff) from refraction and attenuation measurements with moiré deflectometry could be of high interest to various domains of high energy density research, such as shocked materials and inertial confinement fusion experiments, as well as material science and nondestructive testing.

  10. Retinotopic maps and foveal suppression in the visual cortex of amblyopic adults.

    PubMed

    Conner, Ian P; Odom, J Vernon; Schwartz, Terry L; Mendola, Janine D

    2007-08-15

    Amblyopia is a developmental visual disorder associated with loss of monocular acuity and sensitivity as well as profound alterations in binocular integration. Abnormal connections in visual cortex are known to underlie this loss, but the extent to which these abnormalities are regionally or retinotopically specific has not been fully determined. This functional magnetic resonance imaging (fMRI) study compared the retinotopic maps in visual cortex produced by each individual eye in 19 adults (7 esotropic strabismics, 6 anisometropes and 6 controls). In our standard viewing condition, the non-tested eye viewed a dichoptic homogeneous mid-level grey stimulus, thereby permitting some degree of binocular interaction. Regions-of-interest analysis was performed for extrafoveal V1, extrafoveal V2 and the foveal representation at the occipital pole. In general, the blood oxygenation level-dependent (BOLD) signal was reduced for the amblyopic eye. At the occipital pole, population receptive fields were shifted to represent more parafoveal locations for the amblyopic eye, compared with the fellow eye, in some subjects. Interestingly, occluding the fellow eye caused an expanded foveal representation for the amblyopic eye in one early-onset strabismic subject with binocular suppression, indicating real-time cortical remapping. In addition, a few subjects actually showed increased activity in parietal and temporal cortex when viewing with the amblyopic eye. We conclude that, even in a heterogeneous population, abnormal early visual experience commonly leads to regionally specific cortical adaptations.

  11. Remote sensing-based characterization, 2-m, Plant Functional Type Distributions, Barrow Environmental Observatory, 2010

    DOE Data Explorer

    Langford, Zachary; Kumar, Jitendra; Hoffman, Forrest

    2014-01-01

    Arctic ecosystems have been observed to be warming faster than the global average and are predicted to experience accelerated changes in climate due to global warming. Arctic vegetation is particularly sensitive to warming conditions and likely to exhibit shifts in species composition, phenology and productivity under changing climate. Mapping and monitoring of changes in vegetation is essential to understand the effect of climate change on the ecosystem functions. Vegetation exhibits unique spectral characteristics which can be harnessed to discriminate plant types and develop quantitative vegetation indices. We have combined high resolution multi-spectral remote sensing from the WorldView 2 satellite with LIDAR-derived digital elevation models to characterize the tundra landscape on the North Slope of Alaska. Classification of landscape using spectral and topographic characteristics yields spatial regions with expectedly similar vegetation characteristics. A field campaign was conducted during peak growing season to collect vegetation harvests from a number of 1m x 1m plots in the study region, which were then analyzed for distribution of vegetation types in the plots. Statistical relationships were developed between spectral and topographic characteristics and vegetation type distributions at the vegetation plots. These derived relationships were employed to statistically upscale the vegetation distributions for the landscape based on spectral characteristics. Vegetation distributions developed are being used to provide Plant Functional Type (PFT) maps for use in the Community Land Model (CLM).

  12. Differential effects of removing the glucose or saccharin components of a glucose-saccharin mixture in a successive negative contrast paradigm.

    PubMed

    Mitchell, Colin P; Flaherty, Charles F

    2005-03-31

    When rats experience an unexpected decrease in reward value, e.g., from 32% sucrose to 4% sucrose, consummatory behavior abruptly decreases to a level below control subjects that only experience the lesser reward, a phenomenon known as Successive Negative Contrast (SNC). In food deprived rats experiencing downshifts in sucrose concentration, SNC dissipates in 3-4 days, as consummatory behavior in shifted rats recovers to the level of unshifted controls. In Experiment 1 food deprived rats that were given 5 min daily access to a 2% glucose-0.15% saccharin mixture, and subsequently shifted to 2% glucose alone, displayed a dramatic SNC effect relative to rats that only received 2% glucose. This SNC effect was primarily manifested as a decrease in the number of consummatory bursts initiated. Interestingly, intake failed to recover to control levels during eight daily postshift sessions. However, in Experiment 2 subjects that were shifted from the same glucose-saccharin mixture to 0.15% saccharin alone failed to show SNC rather, intake fell to the level of control animals which only received 0.15% saccharin. The data from Experiment 1, in conjunction with previous studies utilizing non-deprived rats, quinine adulteration, or shifts from sucrose to saccharin, show that reductions in taste value can produce contrast effects, but suggest that a threshold caloric value is necessary for recovery. The data from Experiment 2 may suggest that saccharin and glucose do not contribute equally to the enhanced palatability of the mixture.

  13. Analysis of the contributions of ring current and electric field effects to the chemical shifts of RNA bases.

    PubMed

    Sahakyan, Aleksandr B; Vendruscolo, Michele

    2013-02-21

    Ring current and electric field effects can considerably influence NMR chemical shifts in biomolecules. Understanding such effects is particularly important for the development of accurate mappings between chemical shifts and the structures of nucleic acids. In this work, we first analyzed the Pople and the Haigh-Mallion models in terms of their ability to describe nitrogen base conjugated ring effects. We then created a database (DiBaseRNA) of three-dimensional arrangements of RNA base pairs from X-ray structures, calculated the corresponding chemical shifts via a hybrid density functional theory approach and used the results to parametrize the ring current and electric field effects in RNA bases. Next, we studied the coupling of the electric field and ring current effects for different inter-ring arrangements found in RNA bases using linear model fitting, with joint electric field and ring current, as well as only electric field and only ring current approximations. Taken together, our results provide a characterization of the interdependence of ring current and electric field geometric factors, which is shown to be especially important for the chemical shifts of non-hydrogen atoms in RNA bases.

  14. Adaptation to Shift Work: Physiologically Based Modeling of the Effects of Lighting and Shifts’ Start Time

    PubMed Central

    Postnova, Svetlana; Robinson, Peter A.; Postnov, Dmitry D.

    2013-01-01

    Shift work has become an integral part of our life with almost 20% of the population being involved in different shift schedules in developed countries. However, the atypical work times, especially the night shifts, are associated with reduced quality and quantity of sleep that leads to increase of sleepiness often culminating in accidents. It has been demonstrated that shift workers’ sleepiness can be improved by a proper scheduling of light exposure and optimizing shifts timing. Here, an integrated physiologically-based model of sleep-wake cycles is used to predict adaptation to shift work in different light conditions and for different shift start times for a schedule of four consecutive days of work. The integrated model combines a model of the ascending arousal system in the brain that controls the sleep-wake switch and a human circadian pacemaker model. To validate the application of the integrated model and demonstrate its utility, its dynamics are adjusted to achieve a fit to published experimental results showing adaptation of night shift workers (n = 8) in conditions of either bright or regular lighting. Further, the model is used to predict the shift workers’ adaptation to the same shift schedule, but for conditions not considered in the experiment. The model demonstrates that the intensity of shift light can be reduced fourfold from that used in the experiment and still produce good adaptation to night work. The model predicts that sleepiness of the workers during night shifts on a protocol with either bright or regular lighting can be significantly improved by starting the shift earlier in the night, e.g.; at 21∶00 instead of 00∶00. Finally, the study predicts that people of the same chronotype, i.e. with identical sleep times in normal conditions, can have drastically different responses to shift work depending on their intrinsic circadian and homeostatic parameters. PMID:23308206

  15. 6-Aminopenicillanic acid revisited: A combined solid state NMR and in silico refinement

    NASA Astrophysics Data System (ADS)

    Aguiar, Daniel Lima Marques de; San Gil, Rosane Aguiar da Silva; Alencastro, Ricardo Bicca de; Souza, Eugenio Furtado de; Borré, Leandro Bandeira; Vaiss, Viviane da Silva; Leitão, Alexandre Amaral

    2016-09-01

    13C/15N (experimental and ab initio) solid-state NMR was used to achieve an affordable way to improve hydrogen refinement of 6-aminopenicillanic acid (6-APA) structure. The lattice effect on the isotropic chemical shifts was probed by using two different magnetic shielding calculations: isolated molecules and periodic crystal structure. The electron density difference maps of optimized and non-optimized structures were calculated in order to investigate the interactions inside the 6-APA unit cell. The 13C and 15N chemical shifts assignments were unambiguously stablished. In addition, some of the literature 13C resonances ambiguities could be properly solved.

  16. A Three-Dimensional DOSY HMQC Experiment for the High-Resolution Analysis of Complex Mixtures

    NASA Astrophysics Data System (ADS)

    Barjat, Hervé; Morris, Gareth A.; Swanson, Alistair G.

    1998-03-01

    A three-dimensional experiment is described in which NMR signals are separated according to their proton chemical shift,13C chemical shift, and diffusion coefficient. The sequence is built up from a stimulated echo sequence with bipolar field gradient pulses and a conventional decoupled HMQC sequence. Results are presented for a model mixture of quinine, camphene, and geraniol in deuteriomethanol.

  17. Mechanical Stress in InP Structures Etched in an Inductively Coupled Plasma Reactor with Ar/Cl2/CH4 Plasma Chemistry

    NASA Astrophysics Data System (ADS)

    Landesman, Jean-Pierre; Cassidy, Daniel T.; Fouchier, Marc; Pargon, Erwine; Levallois, Christophe; Mokhtari, Merwan; Jimenez, Juan; Torres, Alfredo

    2018-02-01

    We investigated the crystal lattice deformation that can occur during the etching of structures in bulk InP using SiNx hard masks with Ar/Cl2/CH4 chemistries in an inductively coupled plasma reactor. Two techniques were used: degree of polarization (DOP) of the photo-luminescence, which gives information on the state of mechanical stress present in the structures, and spectrally resolved cathodo-luminescence (CL) mapping. This second technique also provides elements on the mechanical stress in the samples through analysis of the spectral shift of the CL intrinsic emission lines. Preliminary DOP mapping experiments have been conducted on the SiNx hard mask patterns without etching the underlying InP. This preliminary study demonstrated the potential of DOP to map mechanical stress quantitatively in the structures. In a second step, InP patterns with various widths between 1 μm and 20 μm, and various depths between 1 μm and 6 μm, were analyzed by the 2 techniques. DOP measurements were made both on the (100) top surface of the samples and on the (110) cleaved cross section. CL measurements were made only from the (100) surface. We observed that inside the etched features, close to the vertical etched walls, there is always some compressive deformation, while it is tensile just outside the etched features. The magnitude of these effects depends on the lateral and depth dimensions of the etched structures, and on the separation between them (the tensile deformation increases between them due to some kind of proximity effect when separation decreases).

  18. Classifying the Diversity of Bus Mapping Systems

    NASA Astrophysics Data System (ADS)

    Said, Mohd Shahmy Mohd; Forrest, David

    2018-05-01

    This study represents the first stage of an investigation into understanding the nature of different approaches to mapping bus routes and bus network, and how they may best be applied in different public transport situations. In many cities, bus services represent an important facet of easing traffic congestion and reducing pollution. However, with the entrenched car culture in many countries, persuading people to change their mode of transport is a major challenge. To promote this modal shift, people need to know what services are available and where (and when) they go. Bus service maps provide an invaluable element of providing suitable public transport information, but are often overlooked by transport planners, and are under-researched by cartographers. The method here consists of the creation of a map evaluation form and performing assessment of published bus networks maps. The analyses were completed by a combination of quantitative and qualitative data analysis of various aspects of cartographic design and classification. This paper focuses on the resulting classification, which is illustrated by a series of examples. This classification will facilitate more in depth investigations into the details of cartographic design for such maps and help direct areas for user evaluation.

  19. Atomic resolved phase map of monolayer MoS2 retrieved by spherical aberration-corrected transport of intensity equation.

    PubMed

    Zhang, Xiaobin; Oshima, Yoshifumi

    2016-10-01

    An atomic resolution phase map, which enables us to observe charge distribution or magnetic properties at an atomic scale, has been pointed out to be retrieved by transport of intensity equation (TIE) when taking two atomic-resolved transmission electron microscope (TEM) images of small defocus difference. In this work, we firstly obtained the atomic-resolved phase maps of an exfoliated molybdenum disulfide sheet using spherical aberration-corrected transmission electron microscope. We successfully observed 60° grain boundary of mechanically exfoliated monolayer molybdenum disulfide sheet. The relative phase shift of a single molybdenum atomic column to the column consisting of two sulfur atoms was obtained to be about 0.01 rad on average, which was about half lower than the simulated TIE phase map, indicating that the individual atomic sites can be distinguished qualitatively. The appropriate condition for retrieving atomic-resolved TIE phase maps was briefly discussed. © The Author 2016. Published by Oxford University Press on behalf of The Japanese Society of Microscopy. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. Comparison of simulation modeling and satellite techniques for monitoring ecological processes

    NASA Technical Reports Server (NTRS)

    Box, Elgene O.

    1988-01-01

    In 1985 improvements were made in the world climatic data base for modeling and predictive mapping; in individual process models and the overall carbon-balance models; and in the interface software for mapping the simulation results. Statistical analysis of the data base was begun. In 1986 mapping was shifted to NASA-Goddard. The initial approach involving pattern comparisons was modified to a more statistical approach. A major accomplishment was the expansion and improvement of a global data base of measurements of biomass and primary production, to complement the simulation data. The main accomplishments during 1987 included: production of a master tape with all environmental and satellite data and model results for the 1600 sites; development of a complete mapping system used for the initial color maps comparing annual and monthly patterns of Normalized Difference Vegetation Index (NDVI), actual evapotranspiration, net primary productivity, gross primary productivity, and net ecosystem production; collection of more biosphere measurements for eventual improvement of the biological models; and development of some initial monthly models for primary productivity, based on satellite data.

  1. Time-Distance Helioseismology Data-Analysis Pipeline for Helioseismic and Magnetic Imager Onboard Solar Dynamics Observatory (SDO-HMI) and Its Initial Results

    NASA Technical Reports Server (NTRS)

    Zhao, J.; Couvidat, S.; Bogart, R. S.; Parchevsky, K. V.; Birch, A. C.; Duvall, Thomas L., Jr.; Beck, J. G.; Kosovichev, A. G.; Scherrer, P. H.

    2011-01-01

    The Helioseismic and Magnetic Imager onboard the Solar Dynamics Observatory (SDO/HMI) provides continuous full-disk observations of solar oscillations. We develop a data-analysis pipeline based on the time-distance helioseismology method to measure acoustic travel times using HMI Doppler-shift observations, and infer solar interior properties by inverting these measurements. The pipeline is used for routine production of near-real-time full-disk maps of subsurface wave-speed perturbations and horizontal flow velocities for depths ranging from 0 to 20 Mm, every eight hours. In addition, Carrington synoptic maps for the subsurface properties are made from these full-disk maps. The pipeline can also be used for selected target areas and time periods. We explain details of the pipeline organization and procedures, including processing of the HMI Doppler observations, measurements of the travel times, inversions, and constructions of the full-disk and synoptic maps. Some initial results from the pipeline, including full-disk flow maps, sunspot subsurface flow fields, and the interior rotation and meridional flow speeds, are presented.

  2. Logarithmic r-θ mapping for hybrid optical neural network filter for multiple objects recognition within cluttered scenes

    NASA Astrophysics Data System (ADS)

    Kypraios, Ioannis; Young, Rupert C. D.; Chatwin, Chris R.; Birch, Phil M.

    2009-04-01

    θThe window unit in the design of the complex logarithmic r-θ mapping for hybrid optical neural network filter can allow multiple objects of the same class to be detected within the input image. Additionally, the architecture of the neural network unit of the complex logarithmic r-θ mapping for hybrid optical neural network filter becomes attractive for accommodating the recognition of multiple objects of different classes within the input image by modifying the output layer of the unit. We test the overall filter for multiple objects of the same and of different classes' recognition within cluttered input images and video sequences of cluttered scenes. Logarithmic r-θ mapping for hybrid optical neural network filter is shown to exhibit with a single pass over the input data simultaneously in-plane rotation, out-of-plane rotation, scale, log r-θ map translation and shift invariance, and good clutter tolerance by recognizing correctly the different objects within the cluttered scenes. We record in our results additional extracted information from the cluttered scenes about the objects' relative position, scale and in-plane rotation.

  3. The Apollo 15 X-ray fluorescence experiment

    NASA Technical Reports Server (NTRS)

    Adler, I.

    1972-01-01

    The objectives of Apollo 15 X-ray fluorescence experiment were to obtain a partial chemical map of a large portion of the moon. Gamma ray and alpha particle experiments were also performed. Mapping information from approximately 150 deg east on the moon to about 50 deg west was secured. Secondary X-rays characteristic of silicon, aluminum, and magnesium were measured.

  4. The 3D Elevation Program—Flood risk management

    USGS Publications Warehouse

    Carswell, William J.; Lukas, Vicki

    2018-01-25

    Flood-damage reduction in the United States has been a longstanding but elusive societal goal. The national strategy for reducing flood damage has shifted over recent decades from a focus on construction of flood-control dams and levee systems to a three-pronged strategy to (1) improve the design and operation of such structures, (2) provide more accurate and accessible flood forecasting, and (3) shift the Federal Emergency Management Agency (FEMA) National Flood Insurance Program to a more balanced, less costly flood-insurance paradigm. Expanding the availability and use of high-quality, three-dimensional (3D) elevation information derived from modern light detection and ranging (lidar) technologies to provide essential terrain data poses a singular opportunity to dramatically enhance the effectiveness of all three components of this strategy. Additionally, FEMA, the National Weather Service, and the U.S. Geological Survey (USGS) have developed tools and joint program activities to support the national strategy.The USGS 3D Elevation Program (3DEP) has the programmatic infrastructure to produce and provide essential terrain data. This infrastructure includes (1) data acquisition partnerships that leverage funding and reduce duplicative efforts, (2) contracts with experienced private mapping firms that ensure acquisition of consistent, low-cost 3D elevation data, and (3) the technical expertise, standards, and specifications required for consistent, edge-to-edge utility across multiple collection platforms and public access unfettered by individual database designs and limitations.High-quality elevation data, like that collected through 3DEP, are invaluable for assessing and documenting flood risk and communicating detailed information to both responders and planners alike. Multiple flood-mapping programs make use of USGS streamflow and 3DEP data. Flood insurance rate maps, flood documentation studies, and flood-inundation map libraries are products of these programs.

  5. THE FORMATION OF IRIS DIAGNOSTICS. VIII. IRIS OBSERVATIONS IN THE C ii 133.5 nm MULTIPLET

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rathore, Bhavna; Pereira, Tiago M. D.; Carlsson, Mats

    The C ii 133.5 nm multiplet has been observed by NASA’s Interface Region Imaging Spectrograph (IRIS) in unprecedented spatial resolution. The aims of this work are to characterize these new observations of the C ii lines, place them in context with previous work, and to identify any additional value the C ii lines bring when compared with other spectral lines. We make use of wide, long exposure IRIS rasters covering the quiet Sun and an active region. Line properties such as velocity shift and width are extracted from individual spectra and analyzed. The lines have a variety of shapes (mostlymore » single-peak or double-peak), are strongest in active regions and weaker in the quiet Sun. The ratio between the 133.4 and 133.5 nm components is always less than 1.8, indicating that their radiation is optically thick in all locations. Maps of the C ii line widths are a powerful new diagnostic of chromospheric structures, and their line shifts are a robust velocity diagnostic. Compared with earlier quiet Sun observations, we find similar absolute intensities and mean line widths, but smaller redshifts; this difference can perhaps be attributed to differences in spectral resolution and spatial coverage. The C ii intensity maps are somewhat similar to those of transition region lines, but also share some features with chromospheric maps such as those from the Mg ii k line, indicating that they are formed between the upper chromosphere and transition region. C ii intensity, width, and velocity maps can therefore be used to gather additional information about the upper chromosphere.« less

  6. A perceptual map for gait symmetry quantification and pathology detection.

    PubMed

    Moevus, Antoine; Mignotte, Max; de Guise, Jacques A; Meunier, Jean

    2015-10-29

    The gait movement is an essential process of the human activity and the result of collaborative interactions between the neurological, articular and musculoskeletal systems, working efficiently together. This explains why gait analysis is important and increasingly used nowadays for the diagnosis of many different types (neurological, muscular, orthopedic, etc.) of diseases. This paper introduces a novel method to quickly visualize the different parts of the body related to an asymmetric movement in the human gait of a patient for daily clinical usage. The proposed gait analysis algorithm relies on the fact that the healthy walk has (temporally shift-invariant) symmetry properties in the coronal plane. The goal is to provide an inexpensive and easy-to-use method, exploiting an affordable consumer depth sensor, the Kinect, to measure the gait asymmetry and display results in a perceptual way. We propose a multi-dimensional scaling mapping using a temporally shift invariant distance, allowing us to efficiently visualize (in terms of perceptual color difference) the asymmetric body parts of the gait cycle of a subject. We also propose an index computed from this map and which quantifies locally and globally the degree of asymmetry. The proposed index is proved to be statistically significant and this new, inexpensive, marker-less, non-invasive, easy to set up, gait analysis system offers a readable and flexible tool for clinicians to analyze gait characteristics and to provide a fast diagnostic. This system, which estimates a perceptual color map providing a quick overview of asymmetry existing in the gait cycle of a subject, can be easily exploited for disease progression, recovery cues from post-operative surgery (e.g., to check the healing process or the effect of a treatment or a prosthesis) or might be used for other pathologies where gait asymmetry might be a symptom.

  7. A new method to measure the virial factors in the reverberation mapping of active galactic nuclei

    NASA Astrophysics Data System (ADS)

    Liu, H. T.; Feng, H. C.; Bai, J. M.

    2017-04-01

    Based on the gravitational red shift, which is a prediction of Einstein's general relativity theory, of broad optical emission lines in active galactic nuclei (AGNs), a new method is proposed to estimate the virial factors f in measuring black hole masses MRM by the reverberation mapping of AGNs. The factors f can be measured based on two physical quantities, I.e. the gravitational red shifts zg and the full widths at half maxima vFWHM of broad lines. In the past, it has been difficult to determine the factors f for individual AGNs. We apply this new method to several reverberation-mapped type 1 Seyfert galaxies. There is a correlation between f and the radius of the broad-line region (BLR) rBLR, f=5.4 r_{BLR}^{0.3}, for the gravitationally red-shifted broad lines He II, He I, Hβ and Hα in the narrow-line type 1 Seyfert galaxy (NLS1) Mrk 110. This correlation results from the influence of the radiation pressure of the accretion disc on the BLR clouds. This influence seems to be more important than usually thought so in AGNs. Mrk 110 has f ≈ 8-16, distinctly larger than the mean ≈ 1 usually used to estimate MRM for vFWHM. NGC 4593 and NLS1 Mrk 486 have f ≈ 3 and f ≈ 9, respectively. Higher f values of several tens are derived for three other NLS1s. There is a correlation between f and accretion rate dot{M}_{f=1}, f=6.8dot{M}^{0.4}_{f=1} for five objects, where dot{M}_{f=1}=dot{M}_{bullet }/L_{Edd}c^{-2} as f = 1 is assumed when estimating MRM used in the Eddington luminosity LEdd, dot{M}_{bullet } is the mass accretion rate, and c is the speed of light. These larger f values will produce higher MRM values and lower Eddington ratios.

  8. An Artist's Journey Through Endangered Lands; conveying hydrological changes and land loss informed and inspired by Science

    NASA Astrophysics Data System (ADS)

    Varisco, M. M.

    2017-12-01

    How do we live with nature? This simple question began a 10 year art-science journey into the dynamic and endangered wetlands of southeast Louisiana and its accelerated coastal decline. Since the 1930s, nearly 1,900 square miles of Louisiana's coast have been lost. How might artworks, informed by science, convey the seriousness and urgency of this loss to a wider public? Artist Michel Varisco engaged in dialogue with environmental scientist Doug Meffert and Dan Etheridge (of Meffert + Etheridge and The Center for Bioenvironmental Research at Tulane and Xavier) about the hydrological changes which have accelerated or mitigated Louisiana's land losses. She was also inspired by the unique underwater studies of biologist Suzanne Fredericq on pollutants in the Gulf from the BP oil spill and of marine ecologist Nancy Rabalais who assesses hypoxia dynamics and their impact on "dead zones." The art work that emerged includes Shifting and Fluid States, as well as current projects Below Sea Level and Turning: prayer wheels for the Mississippi River, an art commission awarded by the City of New Orleans on view during Prospect.4 Art Biennial and AGU. Shifting is a series of large-scale photos shot from the air and water that observe the dynamic movement of the Louisiana coastline over the course of a short but powerful geologic timeline and explores the consequences of human altercations to those lands and waters via land loss and sea level rise. Turning is based on the work of Kate Orff's maps from Petrochemical America and the 1944 maps of Harold Fisk. Fisk pioneered an understanding of alluvial and sedimentological processes of the Mississippi Valley, while Orff's maps describe the Mississippi River from Baton Rouge to New Orleans during three different eras: the wild un-leveed land building era; the plantation, slavery era; and the petrochemical era of present day land loss. Shifting has been exhibited around the world and Turning has already been seen by 50,000 people.

  9. Robust visual object tracking with interleaved segmentation

    NASA Astrophysics Data System (ADS)

    Abel, Peter; Kieritz, Hilke; Becker, Stefan; Arens, Michael

    2017-10-01

    In this paper we present a new approach for tracking non-rigid, deformable objects by means of merging an on-line boosting-based tracker and a fast foreground background segmentation. We extend an on-line boosting- based tracker, which uses axes-aligned bounding boxes with fixed aspect-ratio as tracking states. By constructing a confidence map from the on-line boosting-based tracker and unifying this map with a confidence map, which is obtained from a foreground background segmentation algorithm, we build a superior confidence map. For constructing a rough confidence map of a new frame based on on-line boosting, we employ the responses of the strong classifier as well as the single weak classifier responses that were built before during the updating step. This confidence map provides a rough estimation of the object's position and dimension. In order to refine this confidence map, we build a fine, pixel-wisely segmented confidence map and merge both maps together. Our segmentation method is color-histogram-based and provides a fine and fast image segmentation. By means of back-projection and the Bayes' rule, we obtain a confidence value for every pixel. The rough and the fine confidence maps are merged together by building an adaptively weighted sum of both maps. The weights are obtained by utilizing the variances of both confidence maps. Further, we apply morphological operators in the merged confidence map in order to reduce the noise. In the resulting map we estimate the object localization and dimension via continuous adaptive mean shift. Our approach provides a rotated rectangle as tracking states, which enables a more precise description of non-rigid, deformable objects than axes-aligned bounding boxes. We evaluate our tracker on the visual object tracking (VOT) benchmark dataset 2016.

  10. A unified approach for debugging is-a structure and mappings in networked taxonomies

    PubMed Central

    2013-01-01

    Background With the increased use of ontologies and ontology mappings in semantically-enabled applications such as ontology-based search and data integration, the issue of detecting and repairing defects in ontologies and ontology mappings has become increasingly important. These defects can lead to wrong or incomplete results for the applications. Results We propose a unified framework for debugging the is-a structure of and mappings between taxonomies, the most used kind of ontologies. We present theory and algorithms as well as an implemented system RepOSE, that supports a domain expert in detecting and repairing missing and wrong is-a relations and mappings. We also discuss two experiments performed by domain experts: an experiment on the Anatomy ontologies from the Ontology Alignment Evaluation Initiative, and a debugging session for the Swedish National Food Agency. Conclusions Semantically-enabled applications need high quality ontologies and ontology mappings. One key aspect is the detection and removal of defects in the ontologies and ontology mappings. Our system RepOSE provides an environment that supports domain experts to deal with this issue. We have shown the usefulness of the approach in two experiments by detecting and repairing circa 200 and 30 defects, respectively. PMID:23548155

  11. Using perceptual rules in interactive visualization

    NASA Astrophysics Data System (ADS)

    Rogowitz, Bernice E.; Treinish, Lloyd A.

    1994-05-01

    In visualization, data are represented as variations in grayscale, hue, shape, and texture. They can be mapped to lines, surfaces, and glyphs, and can be represented statically or in animation. In modem visualization systems, the choices for representing data seem unlimited. This is both a blessing and a curse, however, since the visual impression created by the visualization depends critically on which dimensions are selected for representing the data (Bertin, 1967; Tufte, 1983; Cleveland, 1991). In modem visualization systems, the user can interactively select many different mapping and representation operations, and can interactively select processing operations (e.g., applying a color map), realization operations (e.g., generating geometric structures such as contours or streamlines), and rendering operations (e.g., shading or ray-tracing). The user can, for example, map data to a color map, then apply contour lines, then shift the viewing angle, then change the color map again, etc. In many systems, the user can vary the choices for each operation, selecting, for example, particular color maps, contour characteristics, and shading techniques. The hope is that this process will eventually converge on a visual representation which expresses the structure of the data and effectively communicates its message in a way that meets the user's goals. Sometimes, however, it results in visual representations which are confusing, misleading, and garish.

  12. Distortion correction of echo planar images applying the concept of finite rate of innovation to point spread function mapping (FRIP).

    PubMed

    Nunes, Rita G; Hajnal, Joseph V

    2018-06-01

    Point spread function (PSF) mapping enables estimating the displacement fields required for distortion correction of echo planar images. Recently, a highly accelerated approach was introduced for estimating displacements from the phase slope of under-sampled PSF mapping data. Sampling schemes with varying spacing were proposed requiring stepwise phase unwrapping. To avoid unwrapping errors, an alternative approach applying the concept of finite rate of innovation to PSF mapping (FRIP) is introduced, using a pattern search strategy to locate the PSF peak, and the two methods are compared. Fully sampled PSF data was acquired in six subjects at 3.0 T, and distortion maps were estimated after retrospective under-sampling. The two methods were compared for both previously published and newly optimized sampling patterns. Prospectively under-sampled data were also acquired. Shift maps were estimated and deviations relative to the fully sampled reference map were calculated. The best performance was achieved when using FRIP with a previously proposed sampling scheme. The two methods were comparable for the remaining schemes. The displacement field errors tended to be lower as the number of samples or their spacing increased. A robust method for estimating the position of the PSF peak has been introduced.

  13. A geometrical shift results in erroneous appearance of low frequency tissue eddy current induced phase maps.

    PubMed

    Mandija, Stefano; van Lier, Astrid L H M W; Katscher, Ulrich; Petrov, Petar I; Neggers, Sebastian F W; Luijten, Peter R; van den Berg, Cornelis A T

    2016-09-01

    Knowledge on low frequency (LF) tissue conductivity is relevant for various biomedical purposes. To obtain this information, LF phase maps arising from time-varying imaging gradients have been demonstrated to create a LF conductivity contrast. Essential in this methodology is the subtraction of phase images acquired with opposite gradient polarities to separate LF and RF phase effects. Here we demonstrate how sensitive these subtractions are with respect to geometrical distortions. The effect of geometrical distortions on LF phase maps is mathematically defined. After quantifying typical geometrical distortions, their effects on LF phase maps are evaluated using conductive phantoms. For validation, electromagnetic simulations of LF phase maps were performed. Even sub-voxel distortions of 10% of the voxel size, measured for a typical LF MR sequence, cause leakage of RF phase into LF phase of several milli-radians, leading to a misleading pattern of LF phase maps. This leakage is mathematically confirmed, while simulations indicate that the expected LF phase should be in order of micro-radians. The conductivity scaling of LF phase maps is attributable to the RF phase leakage, thus dependent on the RF conductivity. In fact, simulations show that the LF phase is not measurable. Magn Reson Med 76:905-912, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  14. Using task effort and pupil size to track covert shifts of visual attention independently of a pupillary light reflex.

    PubMed

    Brocher, Andreas; Harbecke, Raphael; Graf, Tim; Memmert, Daniel; Hüttermann, Stefanie

    2018-03-07

    We tested the link between pupil size and the task effort involved in covert shifts of visual attention. The goal of this study was to establish pupil size as a marker of attentional shifting in the absence of luminance manipulations. In three experiments, participants evaluated two stimuli that were presented peripherally, appearing equidistant from and on opposite sides of eye fixation. The angle between eye fixation and the peripherally presented target stimuli varied from 12.5° to 42.5°. The evaluation of more distant stimuli led to poorer performance than did the evaluation of more proximal stimuli throughout our study, confirming that the former required more effort than the latter. In addition, in Experiment 1 we found that pupil size increased with increasing angle and that this effect could not be reduced to the operation of low-level visual processes in the task. In Experiment 2 the pupil dilated more strongly overall when participants evaluated the target stimuli, which required shifts of attention, than when they merely reported on the target's presence versus absence. Both conditions yielded larger pupils for more distant than for more proximal stimuli, however. In Experiment 3, we manipulated task difficulty more directly, by changing the contrast at which the target stimuli were presented. We replicated the results from Experiment 1 only with the high-contrast stimuli. With stimuli of low contrast, ceiling effects in pupil size were observed. Our data show that the link between task effort and pupil size can be used to track the degree to which an observer covertly shifts attention to or detects stimuli in peripheral vision.

  15. Stable learning of functional maps in self-organizing spiking neural networks with continuous synaptic plasticity

    PubMed Central

    Srinivasa, Narayan; Jiang, Qin

    2013-01-01

    This study describes a spiking model that self-organizes for stable formation and maintenance of orientation and ocular dominance maps in the visual cortex (V1). This self-organization process simulates three development phases: an early experience-independent phase, a late experience-independent phase and a subsequent refinement phase during which experience acts to shape the map properties. The ocular dominance maps that emerge accommodate the two sets of monocular inputs that arise from the lateral geniculate nucleus (LGN) to layer 4 of V1. The orientation selectivity maps that emerge feature well-developed iso-orientation domains and fractures. During the last two phases of development the orientation preferences at some locations appear to rotate continuously through ±180° along circular paths and referred to as pinwheel-like patterns but without any corresponding point discontinuities in the orientation gradient maps. The formation of these functional maps is driven by balanced excitatory and inhibitory currents that are established via synaptic plasticity based on spike timing for both excitatory and inhibitory synapses. The stability and maintenance of the formed maps with continuous synaptic plasticity is enabled by homeostasis caused by inhibitory plasticity. However, a prolonged exposure to repeated stimuli does alter the formed maps over time due to plasticity. The results from this study suggest that continuous synaptic plasticity in both excitatory neurons and interneurons could play a critical role in the formation, stability, and maintenance of functional maps in the cortex. PMID:23450808

  16. Reconstruction method for fringe projection profilometry based on light beams.

    PubMed

    Li, Xuexing; Zhang, Zhijiang; Yang, Chen

    2016-12-01

    A novel reconstruction method for fringe projection profilometry, based on light beams, is proposed and verified by experiments. Commonly used calibration techniques require the parameters of projector calibration or the reference planes placed in many known positions. Obviously, introducing the projector calibration can reduce the accuracy of the reconstruction result, and setting the reference planes to many known positions is a time-consuming process. Therefore, in this paper, a reconstruction method without projector's parameters is proposed and only two reference planes are introduced. A series of light beams determined by the subpixel point-to-point map on the two reference planes combined with their reflected light beams determined by the camera model are used to calculate the 3D coordinates of reconstruction points. Furthermore, the bundle adjustment strategy and the complementary gray-code phase-shifting method are utilized to ensure the accuracy and stability. Qualitative and quantitative comparisons as well as experimental tests demonstrate the performance of our proposed approach, and the measurement accuracy can reach about 0.0454 mm.

  17. Solution structure and DNA-binding properties of the C-terminal domain of UvrC from E.coli

    PubMed Central

    Singh, S.; Folkers, G.E.; Bonvin, A.M.J.J.; Boelens, R.; Wechselberger, R.; Niztayev, A.; Kaptein, R.

    2002-01-01

    The C-terminal domain of the UvrC protein (UvrC CTD) is essential for 5′ incision in the prokaryotic nucleotide excision repair process. We have determined the three-dimensional structure of the UvrC CTD using heteronuclear NMR techniques. The structure shows two helix–hairpin–helix (HhH) motifs connected by a small connector helix. The UvrC CTD is shown to mediate structure-specific DNA binding. The domain binds to a single-stranded–double-stranded junction DNA, with a strong specificity towards looped duplex DNA that contains at least six unpaired bases per loop (‘bubble DNA’). Using chemical shift perturbation experiments, the DNA-binding surface is mapped to the first hairpin region encompassing the conserved glycine–valine–glycine residues followed by lysine–arginine–arginine, a positively charged surface patch and the second hairpin region consisting of glycine–isoleucine–serine. A model for the protein– DNA complex is proposed that accounts for this specificity. PMID:12426397

  18. On-the-fly machine-learning for high-throughput experiments: search for rare-earth-free permanent magnets

    PubMed Central

    Kusne, Aaron Gilad; Gao, Tieren; Mehta, Apurva; Ke, Liqin; Nguyen, Manh Cuong; Ho, Kai-Ming; Antropov, Vladimir; Wang, Cai-Zhuang; Kramer, Matthew J.; Long, Christian; Takeuchi, Ichiro

    2014-01-01

    Advanced materials characterization techniques with ever-growing data acquisition speed and storage capabilities represent a challenge in modern materials science, and new procedures to quickly assess and analyze the data are needed. Machine learning approaches are effective in reducing the complexity of data and rapidly homing in on the underlying trend in multi-dimensional data. Here, we show that by employing an algorithm called the mean shift theory to a large amount of diffraction data in high-throughput experimentation, one can streamline the process of delineating the structural evolution across compositional variations mapped on combinatorial libraries with minimal computational cost. Data collected at a synchrotron beamline are analyzed on the fly, and by integrating experimental data with the inorganic crystal structure database (ICSD), we can substantially enhance the accuracy in classifying the structural phases across ternary phase spaces. We have used this approach to identify a novel magnetic phase with enhanced magnetic anisotropy which is a candidate for rare-earth free permanent magnet. PMID:25220062

  19. Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool.

    PubMed

    Auerbach, Raymond K; Chen, Bin; Butte, Atul J

    2013-08-01

    Biological analysis has shifted from identifying genes and transcripts to mapping these genes and transcripts to biological functions. The ENCODE Project has generated hundreds of ChIP-Seq experiments spanning multiple transcription factors and cell lines for public use, but tools for a biomedical scientist to analyze these data are either non-existent or tailored to narrow biological questions. We present the ENCODE ChIP-Seq Significance Tool, a flexible web application leveraging public ENCODE data to identify enriched transcription factors in a gene or transcript list for comparative analyses. The ENCODE ChIP-Seq Significance Tool is written in JavaScript on the client side and has been tested on Google Chrome, Apple Safari and Mozilla Firefox browsers. Server-side scripts are written in PHP and leverage R and a MySQL database. The tool is available at http://encodeqt.stanford.edu. abutte@stanford.edu Supplementary material is available at Bioinformatics online.

  20. Application of wire beam electrode technique to investigate initiation and propagation of rebar corrosion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shi, Wei; Dong, Ze Hua, E-mail: zehua.dong@gmail.com; Kong, De Jie

    Multi-electrode technique named as wire beam electrode (WBE) was used to study pitting corrosion of rebar under concrete cover. When WBE embedded mortar sample was immersed in NaCl solution, uneven distributions of galvanic current and open circuit potential (OCP) on the WBE were observed due to the initiation of pitting corrosion. The following oxygen depletion in mortar facilitated the negative shift of the OCP and the smoothing of the current and potential distributions. Wetting–drying cycle experiments showed that corrosion products instead of oxygen in wet mortar specimen sustained the propagation of pitting corrosion due to Fe (III) taking part inmore » cathodic depolarization during oxygen-deficient wet period, which was confirmed by micro-Raman spectroscopy. In addition, new pitting corrosion occurred mainly near the corrosion products, leading to preferentially horizontal propagation of rust layer on the WBE. A localized corrosion factor was further presented to quantify the localised corrosion based on galvanic current maps.« less

  1. Electron density and effective atomic number (Zeff) determination through x-ray Moiré deflectometry

    NASA Astrophysics Data System (ADS)

    Valdivia Leiva, Maria Pia; Stutman, Dan; Finkenthal, Michael

    2014-10-01

    Talbot-Lau based Moiré deflectometry is a powerful density diagnostic capable of delivering refraction information and attenuation from a single image, through the accurate detection of X-ray phase-shift and intensity. The technique is able to accurately measure both the real part of the index of refraction δ (directly related to electron density) and the attenuation coefficient μ of an object placed in the x-ray beam. Since the atomic number Z (or Zeff for a composite sample) is proportional to these quantities, an elemental map of the effective atomic number can be obtained with the ratio of the phase and the absorption image. The determination of Zeff from refraction and attenuation measurements with Moiré deflectometry could be of high interest in various fields of HED research such as shocked materials and ICF experiments as Zeff is linked, by definition, to the x-ray absorption properties of a specific material. This work is supported by U.S. DoE/NNSA Grant No. 435 DENA0001835.

  2. Work and Nonwork Experiences of Employees on Fixed and Rotating Shifts: An Empirical Assessment.

    ERIC Educational Resources Information Center

    Jamal, Muhammad; Jamal, Saleha M.

    1982-01-01

    Investigated the relationship between shift time and use of leisure time, nonwork satisfaction, and mental and physical health among rank-and-file workers and nurses. Found employees working on fixed shift had higher job performance, motivation, and patients' care skill, and probably enjoyed better physical and emotional health. (Author/JAC)

  3. Research and development for a ground-based hydrogen-maser system

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The results of a joint experiment aimed primarily at the determination of the frequency of the H(1) hyperfine transition are reported. The transition frequency value for Cs-133 hyperfine transition is found. The result is the mean of two independent evaluations against the cesium reference, which differ by 0.002 Hz. The one-sigma uncertainty of the value nu sub H is also estimated to be 0.002 Hz. One evaluation is based on wall shift experiments at Harvard University; the other is a result of new wall shift measurement using many storage bulbs of different sizes at the National Bureau of Standards. The experimental procedures and the applied corrections are described. Results for the wall shift and for the frequency of hydrogen are compared with previously published values, and error limits of the experiments are discussed.

  4. Comparison of RAPD Linkage Maps Constructed For a Single Longleaf Pine From Both Haploid and Diploid Mapping Populations

    Treesearch

    Thomas L. Kubisiak; C.Dana Nelson; W.L. Name; M. Stine

    1996-01-01

    Considerable concern has been voiced regarding the reproducibility/transferability of RAPD markers across different genetic backgrounds in genetic mapping experiments. Therefore, separate gametic subsets (mapping populations) were used to construct individual random amplified polymorphic DNA (RAPD) linkage maps for a single longleaf pine (Pinus palustris...

  5. Cadastral Map Assembling Using Generalized Hough Transformation

    NASA Astrophysics Data System (ADS)

    Liu, Fei; Ohyama, Wataru; Wakabayashi, Tetsushi; Kimura, Fumitaka

    There are numerous cadastral maps generated by the past land surveying. The raster digitization of these paper maps is in progress. For effective and efficient use of these maps, we have to assemble the set of maps to make them superimposable on other geographic information in a GIS. The problem can be seen as a complex jigsaw puzzle where the pieces are the cadastral sections extracted from the map. We present an automatic solution to this geographic jigsaw puzzle, based on the generalized Hough transformation that detects the longest common boundary between every piece and its neighbors. The experiments have been conducted using the map of Mie Prefecture, Japan and the French cadastral map. The results of the experiments with the French cadastral maps showed that the proposed method, which consists of a flood filling procedure of internal area and detection and normalization of the north arrow direction, is suitable for assembling the cadastral map. The final goal of the process is to integrate every piece of the puzzle into a national geographic reference frame and database.

  6. Spin-echo based diagonal peak suppression in solid-state MAS NMR homonuclear chemical shift correlation spectra

    NASA Astrophysics Data System (ADS)

    Wang, Kaiyu; Zhang, Zhiyong; Ding, Xiaoyan; Tian, Fang; Huang, Yuqing; Chen, Zhong; Fu, Riqiang

    2018-02-01

    The feasibility of using the spin-echo based diagonal peak suppression method in solid-state MAS NMR homonuclear chemical shift correlation experiments is demonstrated. A complete phase cycling is designed in such a way that in the indirect dimension only the spin diffused signals are evolved, while all signals not involved in polarization transfer are refocused for cancellation. A data processing procedure is further introduced to reconstruct this acquired spectrum into a conventional two-dimensional homonuclear chemical shift correlation spectrum. A uniformly 13C, 15N labeled Fmoc-valine sample and the transmembrane domain of a human protein, LR11 (sorLA), in native Escherichia coli membranes have been used to illustrate the capability of the proposed method in comparison with standard 13C-13C chemical shift correlation experiments.

  7. The association of shift-level nurse staffing with adverse patient events.

    PubMed

    Patrician, Patricia A; Loan, Lori; McCarthy, Mary; Fridman, Moshe; Donaldson, Nancy; Bingham, Mona; Brosch, Laura R

    2011-02-01

    The objective of this study was to demonstrate the association between nurse staffing and adverse events at the shift level. Despite a growing body of research linking nurse staffing and patient outcomes, the relationship of staffing to patient falls and medication errors remains equivocal, possibly due to dependence on aggregated data. Thirteen military hospitals participated in creating a longitudinal nursing outcomes database to monitor nurse staffing, patient falls and medication errors, and other outcomes. Unit types were analyzed separately to stratify patient and nurse staffing characteristics. Bayesian hierarchical logistic regression modeling was used to examine associations between staffing and adverse events. RN skill mix, total nursing care hours, and experience, measured by a proxy variable, were associated with shift-level adverse events. Consideration must be given to nurse staffing and experience levels on every shift.

  8. Toddlers Default to Canonical Surface-to-Meaning Mapping When Learning Verbs

    PubMed Central

    Dautriche, Isabelle; Cristia, Alejandrina; Brusini, Perrine; Yuan, Sylvia; Fisher, Cynthia; Christophe, Anne

    2013-01-01

    Previous work has shown that toddlers readily encode each noun in the sentence as a distinct argument of the verb. However, languages allow multiple mappings between form and meaning which do not fit this canonical format. Two experiments examined French 28-month-olds’ interpretation of right-dislocated sentences (nouni-verb, nouni) where the presence of clear, language-specific cues should block such a canonical mapping. Toddlers (N = 96) interpreted novel verbs embedded in these sentences as transitive, disregarding prosodic cues to dislocation (Experiment 1) but correctly interpreted right-dislocated sentences containing well-known verbs (Experiment 2). These results suggest that toddlers can integrate multiple cues in ideal conditions, but default to canonical surface-to-meaning mapping when extracting structural information about novel verbs in semantically impoverished conditions. PMID:24117408

  9. Mapping experiment with space station

    NASA Technical Reports Server (NTRS)

    Wu, Sherman S. C.

    1987-01-01

    Mapping the earth from space stations can be approached in two areas. One is to collect gravity data for defining a new topographic datum using the earth's gravitational field in terms of spherical harmonics. The other, which should be considered as a very significant contribution of the Space Station, is to search and explore techniques of mapping the earth's topography using either optical or radar images with or without references to ground control points. Geodetic position of ground control points can be predetermined by the Global Positioning System (GPS) for the mapping experiment with the Space Station. It is proposed to establish four ground control points in North America or Africa (including the Sahara Desert). If this experiment should be successfully accomplished, it may also be applied to the defense charting service.

  10. Underground coal mining section data

    NASA Technical Reports Server (NTRS)

    Gabrill, C. P.; Urie, J. T.

    1981-01-01

    A set of tables which display the allocation of time for ten personnel and eight pieces of underground coal mining equipment to ten function categories is provided. Data from 125 full shift time studies contained in the KETRON database was utilized as the primary source data. The KETRON activity and delay codes were mapped onto JPL equipment, personnel and function categories. Computer processing was then performed to aggregate the shift level data and generate the matrices. Additional, documented time study data were analyzed and used to supplement the KETRON databased. The source data including the number of shifts are described. Specific parameters of the mines from which there data were extracted are presented. The result of the data processing including the required JPL matrices is presented. A brief comparison with a time study analysis of continuous mining systems is presented. The procedures used for processing the source data are described.

  11. On the recent destabilization of the Gulf Stream path downstream of Cape Hatteras

    NASA Astrophysics Data System (ADS)

    Andres, M.

    2016-09-01

    Mapped satellite altimetry reveals interannual variability in the position of initiation of Gulf Stream meanders downstream of Cape Hatteras. The longitude where the Gulf Stream begins meandering varies by 1500 km. There has been a general trend for the destabilization point to shift west, and 5 of the last 6 years had a Gulf Stream destabilization point upstream of the New England Seamounts. Independent in situ data suggest that this shift has increased both upper-ocean/deep-ocean interaction events at Line W and open-ocean/shelf interactions across the Middle Atlantic Bight (MAB) shelf break. Mooring data and along-track altimetry indicate a recent increase in the number of deep cyclones that stir Deep Western Boundary Current waters from the MAB slope into the deep interior. Temperature profiles from the Oleander Program suggest that recent enhanced warming of the MAB shelf may be related to shifts in the Gulf Stream's destabilization point.

  12. A Synaptic Basis for Memory Storage in the Cerebral Cortex

    NASA Astrophysics Data System (ADS)

    Bear, Mark F.

    1996-11-01

    A cardinal feature of neurons in the cerebral cortex is stimulus selectivity, and experience-dependent shifts in selectivity are a common correlate of memory formation. We have used a theoretical ``learning rule,'' devised to account for experience-dependent shifts in neuronal selectivity, to guide experiments on the elementary mechanisms of synaptic plasticity in hippocampus and neocortex. These experiments reveal that many synapses in hippocampus and neocortex are bidirectionally modifiable, that the modifications persist long enough to contribute to long-term memory storage, and that key variables governing the sign of synaptic plasticity are the amount of NMDA receptor activation and the recent history of cortical activity.

  13. The application of the piecewise linear approximation to the spectral neighborhood of soil line for the analysis of the quality of normalization of remote sensing materials

    NASA Astrophysics Data System (ADS)

    Kulyanitsa, A. L.; Rukhovich, A. D.; Rukhovich, D. D.; Koroleva, P. V.; Rukhovich, D. I.; Simakova, M. S.

    2017-04-01

    The concept of soil line can be to describe the temporal distribution of spectral characteristics of the bare soil surface. In this case, the soil line can be referred to as the multi-temporal soil line, or simply temporal soil line (TSL). In order to create TSL for 8000 regular lattice points for the territory of three regions of Tula oblast, we used 34 Landsat images obtained in the period from 1985 to 2014 after their certain transformation. As Landsat images are the matrices of the values of spectral brightness, this transformation is the normalization of matrices. There are several methods of normalization that move, rotate, and scale the spectral plane. In our study, we applied the method of piecewise linear approximation to the spectral neighborhood of soil line in order to assess the quality of normalization mathematically. This approach allowed us to range normalization methods according to their quality as follows: classic normalization > successive application of the turn and shift > successive application of the atmospheric correction and shift > atmospheric correction > shift > turn > raw data. The normalized data allowed us to create the maps of the distribution of a and b coefficients of the TSL. The map of b coefficient is characterized by the high correlation with the ground-truth data obtained from 1899 soil pits described during the soil surveys performed by the local institute for land management (GIPROZEM).

  14. Direct mapping between exchange potentials of Hartree-Fock and Kohn-Sham schemes as origin of orbital proximity

    NASA Astrophysics Data System (ADS)

    Cinal, M.

    2010-01-01

    It is found that for closed-l-shell atoms, the exact local exchange potential vx(r) calculated in the exchange-only Kohn-Sham (KS) scheme of the density functional theory (DFT) is very well represented within the region of every atomic shell by each of the suitably shifted potentials obtained with the nonlocal Fock exchange operator for the individual Hartree-Fock (HF) orbitals belonging to this shell. This newly revealed property is not related to the well-known steplike shell structure in the response part of vx(r), but it results from specific relations satisfied by the HF orbital exchange potentials. These relations explain the outstanding proximity of the occupied HF and exchange-only KS orbitals as well as the high quality of the Krieger-Li-Iafrate and localized HF (or, equivalently, common-energy-denominator) approximations to the DFT exchange potential vx(r). Another highly accurate representation of vx(r) is given by the continuous piecewise function built of shell-specific exchange potentials, each defined as the weighted average of the shifted orbital exchange potentials corresponding to a given shell. The constant shifts added to the HF orbital exchange potentials, to map them onto vx(r), are nearly equal to the differences between the energies of the corresponding KS and HF orbitals. It is discussed why these differences are positive and grow when the respective orbital energies become lower for inner orbitals.

  15. Large area robust identification of snow cover from multitemporal COSMO-SkyMed images

    NASA Astrophysics Data System (ADS)

    Pettinato, S.; Santi, E.; Paloscia, S.; Aiazzi, B.; Baronti, S.; Palchetti, E.; Garzelli, A.

    2015-10-01

    This paper investigates the ability of the Information Theoretic Snow Detection Algorithm (ITSDA) in detecting changes due to snow cover between summer and winter seasons on large area images acquired by COSMO-SkyMed constellation. ITSDA is a method for change detection in multitemporal SAR images, which has been recently applied by the authors to a subset of Cosmo-SkyMed data. The proposed technique is based on a nonparametric approach in the framework of Shannon's information theory, and in particular it features the conditional probability of the local means between the two images taken at different times. Such an unsupervised approach does not require any preliminary despeckling procedure to be performed before the calculation of the change map. In the case of a low quantity of anomalous changes in relatively small-size images, a mean shift procedure can be utilized for refining the map. However, in the present investigation, the changes to be identified are pervasive in large size images. Consequently, for computational issues, the mean shift refinement has been omitted in the present work. However, a simplified implementation of mean shift procedure to save time will be possibly considered in future submissions. In any case, the present version of ITSDA method preserve its characteristics of flexibility and sensibility to backscattering changes, thanks to the possibility of setting up the number of quantization levels in the estimation of the conditional probability between the amplitude values at the two acquisition dates.

  16. Mapping the droplet transfer modes for an ER100S-1 GMAW electrode

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Heald, P.R.; Madigan, R.B.; Siewert, T.A.

    1994-02-01

    Welds were made with a 1.2-mm-diameter AWS ER100S-1 electrode using Ar-2% O[sub 2] shielding gas to map the effects of contact-tube-to-work distance (13, 19 and 25 mm), current, voltage, and wire feed rate on metal transfer. The droplet transfer modes were identified for each map by both the sound of the arc and images from a laser back-lit high-speed video system. The modes were correlated to digital records of the voltage and current fluctuations. The maps contain detailed information on the spray transfer mode, including the boundaries of drop spray, streaming spray and rotating spray modes. The metal transfer modemore » boundaries shifted with an increase in contact-tube-to-work distance. Increasing the contact-tube-to-work distance from 13 to 19 mm resulted in a 15 mm/s increase in the wire feet rate for the globular-to-drop-spray transition.« less

  17. Doppler-Zeeman mapping of the magnetic CP star HD 215441

    NASA Astrophysics Data System (ADS)

    Khokhlova, V. L.; Vasilchenko, D. V.; Stepanov, V. V.; Tsymbal, V. V.

    1997-07-01

    The method of Vasilchenko et al. (1996) is used to obtain a Doppler-Zeeman map of the magnetic CP star HD 215441. The magnetic field is approximated by a magnetic dipole that is arbitrarily shifted from the star center. The solution of the inverse problem yields the dipole parameters and the maps of Si, Ti, Cr, and Fe abundance anomalies; the coordinates of local magnetic vectors on the star surface are computed. A comparison of the distribution of abundance anomalies and the magnetic-field configuration reveals that in the region where the magnetic-field lines are vertical (near the magnetic pole), Si, Ti and Cr are highly deficient, while the Fe enhancement is strongest. In the regions where the magnetic-field lines are horizontal (near the magnetic equator), Si, Ti and Cr show the greatest overabundance. In these regions, the Fe abundance is also slightly enhanced and exhibits, as it were, a secondary maximum. The factors that limit the accuracy of Doppler-Zeeman mapping are reviewed.

  18. In Situ Optical Mapping of Voltage and Calcium in the Heart

    PubMed Central

    Ewart, Paul; Ashley, Euan A.; Loew, Leslie M.; Kohl, Peter; Bollensdorff, Christian; Woods, Christopher E.

    2012-01-01

    Electroanatomic mapping the interrelation of intracardiac electrical activation with anatomic locations has become an important tool for clinical assessment of complex arrhythmias. Optical mapping of cardiac electrophysiology combines high spatiotemporal resolution of anatomy and physiological function with fast and simultaneous data acquisition. If applied to the clinical setting, this could improve both diagnostic potential and therapeutic efficacy of clinical arrhythmia interventions. The aim of this study was to explore this utility in vivo using a rat model. To this aim, we present a single-camera imaging and multiple light-emitting-diode illumination system that reduces economic and technical implementation hurdles to cardiac optical mapping. Combined with a red-shifted calcium dye and a new near-infrared voltage-sensitive dye, both suitable for use in blood-perfused tissue, we demonstrate the feasibility of in vivo multi-parametric imaging of the mammalian heart. Our approach combines recording of electrophysiologically-relevant parameters with observation of structural substrates and is adaptable, in principle, to trans-catheter percutaneous approaches. PMID:22876327

  19. A procedure used for a ground truth study of a land use map of North Alabama generated from LANDSAT data

    NASA Technical Reports Server (NTRS)

    Downs, S. W., Jr.; Sharma, G. C.; Bagwell, C.

    1977-01-01

    A land use map of a five county area in North Alabama was generated from LANDSAT data using a supervised classification algorithm. There was good overall agreement between the land use designated and known conditions, but there were also obvious discrepancies. In ground checking the map, two types of errors were encountered - shift and misclassification - and a method was developed to eliminate or greatly reduce the errors. Randomly selected study areas containing 2,525 pixels were analyzed. Overall, 76.3 percent of the pixels were correctly classified. A contingency coefficient of correlation was calculated to be 0.7 which is significant at the alpha = 0.01 level. The land use maps generated by computers from LANDSAT data are useful for overall land use by regional agencies. However, care must be used when making detailed analysis of small areas. The procedure used for conducting the ground truth study together with data from representative study areas is presented.

  20. Bodies as evidence: Mapping new terrain for teen pregnancy and parenting.

    PubMed

    Gubrium, Aline C; Fiddian-Green, Alice; Jernigan, Kasey; Krause, Elizabeth L

    2016-01-01

    Predominant approaches to teen pregnancy focus on decreasing numbers of teen mothers, babies born to them, and state dollars spent to support their families. This overshadows the structural violence interwoven into daily existence for these young parents. This paper argues for the increased use of participatory visual methods to compliment traditional research methods in shifting notions of what counts as evidence in response to teen pregnancy and parenting. We present the methods and results from a body mapping workshop as part of 'Hear Our Stories: Diasporic Youth for Sexual Rights and Justice', a project that examines structural barriers faced by young parenting Latinas and seeks to develop relevant messaging and programming to support and engage youth. Body mapping, as an engaging, innovative participatory visual methodology, involves young parenting women and other marginalised populations in drawing out a deeper understanding of sexual health inequities. Our findings highlight the ways body mapping elicits bodies as evidence to understand young motherhood and wellbeing.

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