XML-Based SHINE Knowledge Base Interchange Language
NASA Technical Reports Server (NTRS)
James, Mark; Mackey, Ryan; Tikidjian, Raffi
2008-01-01
The SHINE Knowledge Base Interchange Language software has been designed to more efficiently send new knowledge bases to spacecraft that have been embedded with the Spacecraft Health Inference Engine (SHINE) tool. The intention of the behavioral model is to capture most of the information generally associated with a spacecraft functional model, while specifically addressing the needs of execution within SHINE and Livingstone. As such, it has some constructs that are based on one or the other.
SHINE Virtual Machine Model for In-flight Updates of Critical Mission Software
NASA Technical Reports Server (NTRS)
Plesea, Lucian
2008-01-01
This software is a new target for the Spacecraft Health Inference Engine (SHINE) knowledge base that compiles a knowledge base to a language called Tiny C - an interpreted version of C that can be embedded on flight processors. This new target allows portions of a running SHINE knowledge base to be updated on a "live" system without needing to halt and restart the containing SHINE application. This enhancement will directly provide this capability without the risk of software validation problems and can also enable complete integration of BEAM and SHINE into a single application. This innovation enables SHINE deployment in domains where autonomy is used during flight-critical applications that require updates. This capability eliminates the need for halting the application and performing potentially serious total system uploads before resuming the application with the loss of system integrity. This software enables additional applications at JPL (microsensors, embedded mission hardware) and increases the marketability of these applications outside of JPL.
Desai, Amy; Smith, Laura E.; Mbuya, Mduduzi N. N.; Chigumira, Ancikaria; Fundira, Dadirai; Tavengwa, Naume V.; Malaba, Thokozile R.; Majo, Florence D.; Humphrey, Jean H.; Stoltzfus, Rebecca J.
2015-01-01
The Sanitation Hygiene Infant Nutrition Efficacy (SHINE) trial is designed to measure the independent and combined effects of improved water, sanitation, and hygiene and improved infant feeding on child stunting and anemia in Zimbabwe. We developed and pilot-tested the infant feeding intervention delivered by 9 village health workers to 19 mothers of infants aged 7–12 months. Between September 2010 and January 2011, maternal knowledge was assessed using mixed methods, and infant nutrient intakes were assessed by 24-hour recall. We observed positive shifts in mothers' knowledge. At baseline, 63% of infants met their energy requirement and most did not receive enough folate, zinc, or calcium; none met their iron requirement. Postintervention, all infants received sufficient fat and vitamin A, and most consumed enough daily energy (79%), protein (95%), calcium (89%), zinc (89%), folate (68%), and iron (68%). The SHINE trial infant feeding intervention led to significant short-term improvements in maternal learning and infant nutrient intakes. PMID:26602298
Knowledge and Racial Violence: The Shine and Shadow of 'Powerful Knowledge'
ERIC Educational Resources Information Center
Rudolph, Sophie; Sriprakash, Arathi; Gerrard, Jessica
2018-01-01
This paper offers a critique of 'powerful knowledge'--a concept in Education Studies that has been presented as a just basis for school curricula. Powerful knowledge is disciplinary knowledge produced and refined through a process of 'specialisation' that usually occurs in universities. Drawing on postcolonial, decolonial and Indigenous studies,…
FAIL-SAFE: Fault Aware IntelLigent Software for Exascale
2016-06-13
and that these programs can continue to correct solutions. To broaden the impact of this research, we also needed to be able to ameliorate errors...designing an interface between the application and an introspection framework for resilience ( IFR ) based on the inference engine SHINE; (4) using...the ROSE compiler to translate annotations into reasoning rules for the IFR ; and (5) designing a Knowledge/Experience Database, which will store
Test plan for formulation and evaluation of grouted waste forms with shine process wastes
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ebert, W. L.; Jerden, J. L.
2015-09-01
The objective of this experimental project is to demonstrate that waste streams generated during the production of Mo99 by the SHINE Medical Technologies (SHINE) process can be immobilized in cement-based grouted waste forms having physical, chemical, and radiological stabilities that meet regulatory requirements for handling, storage, transport, and disposal.
Automatic Testcase Generation for Flight Software
NASA Technical Reports Server (NTRS)
Bushnell, David Henry; Pasareanu, Corina; Mackey, Ryan M.
2008-01-01
The TacSat3 project is applying Integrated Systems Health Management (ISHM) technologies to an Air Force spacecraft for operational evaluation in space. The experiment will demonstrate the effectiveness and cost of ISHM and vehicle systems management (VSM) technologies through onboard operation for extended periods. We present two approaches to automatic testcase generation for ISHM: 1) A blackbox approach that views the system as a blackbox, and uses a grammar-based specification of the system's inputs to automatically generate *all* inputs that satisfy the specifications (up to prespecified limits); these inputs are then used to exercise the system. 2) A whitebox approach that performs analysis and testcase generation directly on a representation of the internal behaviour of the system under test. The enabling technologies for both these approaches are model checking and symbolic execution, as implemented in the Ames' Java PathFinder (JPF) tool suite. Model checking is an automated technique for software verification. Unlike simulation and testing which check only some of the system executions and therefore may miss errors, model checking exhaustively explores all possible executions. Symbolic execution evaluates programs with symbolic rather than concrete values and represents variable values as symbolic expressions. We are applying the blackbox approach to generating input scripts for the Spacecraft Command Language (SCL) from Interface and Control Systems. SCL is an embedded interpreter for controlling spacecraft systems. TacSat3 will be using SCL as the controller for its ISHM systems. We translated the SCL grammar into a program that outputs scripts conforming to the grammars. Running JPF on this program generates all legal input scripts up to a prespecified size. Script generation can also be targeted to specific parts of the grammar of interest to the developers. These scripts are then fed to the SCL Executive. ICS's in-house coverage tools will be run to measure code coverage. Because the scripts exercise all parts of the grammar, we expect them to provide high code coverage. This blackbox approach is suitable for systems for which we do not have access to the source code. We are applying whitebox test generation to the Spacecraft Health INference Engine (SHINE) that is part of the ISHM system. In TacSat3, SHINE will execute an on-board knowledge base for fault detection and diagnosis. SHINE converts its knowledge base into optimized C code which runs onboard TacSat3. SHINE can translate its rules into an intermediate representation (Java) suitable for analysis with JPF. JPF will analyze SHINE's Java output using symbolic execution, producing testcases that can provide either complete or directed coverage of the code. Automatically generated test suites can provide full code coverage and be quickly regenerated when code changes. Because our tools analyze executable code, they fully cover the delivered code, not just models of the code. This approach also provides a way to generate tests that exercise specific sections of code under specific preconditions. This capability gives us more focused testing of specific sections of code.
NASA Technical Reports Server (NTRS)
2001-01-01
Moen Incorporated identified a market need for more durable polished brass plumbing fixtures. NASA's Glenn Research Center is a leader in surface coating technology, which enhances the physical properties of a wide range of materials. The collaborative efforts of Glenn and Moen resulted in a new polished brass finish called LifeShine(R). Based on testing results generated at NASA Glenn, Moen was able to manufacture an affordable, polished brass finish that is as durable as chrome, and resists deterioration. LifeShine is guaranteed to resist normal wear and tear and is even scratch-resistant to cleaning products as abrasive as steel wool. Moen was able to incorporate other colors into the LifeShine finish technology including classic gold, nickel, Satine(TM), Black Opal(TM), stainless, and copper. The company added titanium to LifeShine, making the finish even stronger and increasing its already superior durability. Highly resistant to salt and humidity, the LifeShine finish will remain intact even when the fixture is dented.
Hetherington, Erin; Eggers, Matthijs; Wamoyi, Joyce; Hatfield, Jennifer; Manyama, Mange; Kutz, Susan; Bastien, Sheri
2017-02-07
Diarrheal disease is a major cause of mortality and morbidity in low and middle income countries with children being disproportionately affected. Project SHINE (Sanitation & Hygiene INnovation in Education) is a grassroots participatory science education and social entrepreneurship model to engage youth and the wider community in the development of sustainable strategies to improve sanitation and hygiene. Based in rural and remote Tanzania, this pilot study engaged pastoralist high-school students and communities in the development and evaluation of culturally and contextually relevant strategies to improve sanitation and hygiene. Using a train-the-trainer approach, key activities included teacher workshops, school-based lessons, extra-curricular activities, community events and a One Health sanitation science fair which showcased projects related to water, sanitation and hygiene in relation to human and animal health. The process and outcome of the study were evaluated through qualitative interviews and focus group discussions with diverse project participants, as well as pre- and post- questionnaires completed by students on knowledge, attitudes and practices concerning sanitation and hygiene. The questionnaire results at baseline and follow-up showed statistically significant improvements on key measures including a decrease in unhygienic behaviors, an increase in the perceived importance of handwashing and intention to use the toilet, and increased communication in the social network about the importance of clean water and improved sanitation and hygiene practices, however there were no significant changes in sanitation related knowledge. Qualitative data highlighted strong leadership emerging from youth and enthusiasm from teachers and students concerning the overall approach in the project, including the use of participatory methods. There was a high degree of community engagement with hundreds of community members participating in school-based events. Sanitation science fair projects addressed a range of pastoralist questions and concerns regarding the relationship between water, sanitation and hygiene. Several projects, such as making soap from local materials, demonstrate potential as a sustainable strategy to improve health and livelihoods in the long-term. The Project SHINE model shows promise as an innovative capacity building approach and as an engagement and empowerment strategy for youth and communities to develop locally sustainable strategies to improve sanitation and hygiene.
Algorithm Optimally Orders Forward-Chaining Inference Rules
NASA Technical Reports Server (NTRS)
James, Mark
2008-01-01
People typically develop knowledge bases in a somewhat ad hoc manner by incrementally adding rules with no specific organization. This often results in a very inefficient execution of those rules since they are so often order sensitive. This is relevant to tasks like Deep Space Network in that it allows the knowledge base to be incrementally developed and have it automatically ordered for efficiency. Although data flow analysis was first developed for use in compilers for producing optimal code sequences, its usefulness is now recognized in many software systems including knowledge-based systems. However, this approach for exhaustively computing data-flow information cannot directly be applied to inference systems because of the ubiquitous execution of the rules. An algorithm is presented that efficiently performs a complete producer/consumer analysis for each antecedent and consequence clause in a knowledge base to optimally order the rules to minimize inference cycles. An algorithm was developed that optimally orders a knowledge base composed of forwarding chaining inference rules such that independent inference cycle executions are minimized, thus, resulting in significantly faster execution. This algorithm was integrated into the JPL tool Spacecraft Health Inference Engine (SHINE) for verification and it resulted in a significant reduction in inference cycles for what was previously considered an ordered knowledge base. For a knowledge base that is completely unordered, then the improvement is much greater.
ERIC Educational Resources Information Center
Heilker, Paul; Yergeau, Melanie
2011-01-01
Autism is a profoundly rhetorical phenomenon. And all--parents, educators, caregivers, policymakers, the public, and autistic people themselves--would be significantly empowered to understand and respond to it as such. In the continuing absence of stable scientific or medical knowledge about autism, one needs to shine a bright and insistent light…
78 FR 73897 - SHINE Medical Technologies, Inc.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-09
... NUCLEAR REGULATORY COMMISSION [Docket No. 50-608; NRC-2013-0053] SHINE Medical Technologies, Inc. AGENCY: Nuclear Regulatory Commission. ACTION: License application; docketing. SUMMARY: The U.S. Nuclear... construction permit, submitted by SHINE Medical Technologies, Inc. (SHINE) is acceptable for docketing...
78 FR 39343 - SHINE Medical Technologies, Inc.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-01
... NUCLEAR REGULATORY COMMISSION [Docket No. 50-608; NRC-2013-0053] SHINE Medical Technologies, Inc... entering the comment submissions into ADAMS. II. Discussion SHINE Medical Technologies, Inc. (SHINE) has... sites, and alternative technologies to produce radioisotopes. This notice is being published in...
78 FR 29390 - Applications; SHINE Medical Technologies, Inc.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-20
... NUCLEAR REGULATORY COMMISSION [Proj-0792; NRC-2013-0053] Applications; SHINE Medical Technologies, Inc. AGENCY: Nuclear Regulatory Commission. ACTION: Notice; receipt and availability. FOR FURTHER... (ADAMS) Accession No. ML13088A192), SHINE Medical Technologies (SHINE) filed with the U.S. Nuclear...
78 FR 52579 - SHINE Medical Technologies, Inc.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-23
... NUCLEAR REGULATORY COMMISSION [Docket No. 50-608; NRC-2013-0053] SHINE Medical Technologies, Inc. AGENCY: Nuclear Regulatory Commission. ACTION: Notice of receipt and availability. SUMMARY: The U.S... application for a construction permit, submitted by SHINE Medical Technologies, Inc. (SHINE). ADDRESSES...
Karat, pulque, and gac: three shining stars in the traditional food galaxy.
Kuhnlein, Harriet V
2004-11-01
Karat banana, pulque prepared from Agave species, and gac fruit are three traditional local food items recently studied intensively for their nutrition potential among traditional and indigenous peoples, and are examples of how local food-based strategies can be used to ensure micronutrient nutrition. Successful health promotion and intervention programs emphasizing traditional food systems are few in the international literature, but offer promise in understanding the potential of food-based strategies. Traditional food strategies could be used not only for alleviating malnutrition, but also for developing locally relevant programs for stemming the nutrition transition and preventing chronic disease, particularly among indigenous and traditional peoples who retain knowledge of using food species in their local ecosystems.
78 FR 39342 - SHINE Medical Technologies, Inc.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-01
... NUCLEAR REGULATORY COMMISSION [Docket No. 50-608; NRC-2013-0053] SHINE Medical Technologies, Inc... Technologies, Inc., is acceptable for docketing. ADDRESSES: Please refer to Docket ID NRC-2013-0053 when...: [email protected] . SUPPLEMENTARY INFORMATION: On March 26, 2013, SHINE Medical Technologies (SHINE...
NASA Shines a Spotlight on a Webb Telescope Test
2013-12-11
Dressed in a clean room suit, NASA photographer Desiree Stover shines a light on the Space Environment Simulator's Integration Frame inside the thermal vacuum chamber at NASA's Goddard Space Flight Center in Greenbelt, Md. Shortly after, the chamber was closed up and engineers used this frame to enclose and help cryogenic (cold) test the heart of the James Webb Space Telescope, the Integrated Science Instrument Module. Credit: NASA/Goddard/Chris Gunn NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Katherine J. Elliott; James M. Vose; William A. Jackson
2013-01-01
We used the Nutrient Cycling Model (NuCM) to simulate the effects of various sulfur (S) and nitrogen (N) deposition scenarios on wilderness areas in Western North Carolina. Linville Gorge Wilderness (LGW) and Shining Rock Wilderness (SRW) were chosen because they are high elevation acidic cove forests and are located on geologic parent material known to be low in base...
Project SunSHINE: A Student Based Solar Research Program
NASA Astrophysics Data System (ADS)
Donahue, R.
2000-12-01
Eastchester Middle School (NY) is currently conducting an ongoing, interdisciplinary solar research program entitled Project SunSHINE, for Students Help Investigate Nature in Eastchester. Students are to determine how ultraviolet and visible light levels vary throughout the year at the school's geographic location, and to ascertain if any measured variations correlate to daily weather conditions or sunspot activity. The educational goal is to provide students the opportunity to conduct original and meaningful scientific research, while learning to work collaboratively with peers and teachers in accordance with national mathematics, science and technology standards. Project SunSHINE requires the student researchers to employ a number of technologies to collect and analyze data, including light sensors, astronomical imaging software, an onsite AirWatch Weather Station, Internet access to retrieve daily solar images from the National Solar Observatory's Kitt Peak Vacuum Telescope, and two wide field telescopes for live sunspot observations. The program has been integrated into the science, mathematics, health and computer technology classes. Solar and weather datasets are emailed weekly to physicist Dr. Gil Yanow of the Jet Propulsion Laboratory for inclusion in his global study of light levels. Dr. Yanow credited the Project SunSHINE student researchers last year for the discovery of an inverse relationship between relative humidity and ultraviolet light levels. The Journal News Golden Apple Awards named Project SunSHINE the 1999 New York Wired Applied Technology Award winner. This honor recognizes the year's outstanding educational technology program at both the elementary and secondary level, and included a grant of \\$20,000 to the research program. Teacher training and image processing software for Project SunSHINE has been supplied by The Use of Astronomy in Research Based Science Education (RBSE), a Teacher Enhancement Program funded by the National Science Foundation and conducted at the facilities of the National Optical Astronomy Observatory in Tucson, Arizona.
The Offline Software Framework of the NA61/SHINE Experiment
NASA Astrophysics Data System (ADS)
Sipos, Roland; Laszlo, Andras; Marcinek, Antoni; Paul, Tom; Szuba, Marek; Unger, Michael; Veberic, Darko; Wyszynski, Oskar
2012-12-01
NA61/SHINE (SHINE = SPS Heavy Ion and Neutrino Experiment) is an experiment at the CERN SPS using the upgraded NA49 hadron spectrometer. Among its physics goals are precise hadron production measurements for improving calculations of the neutrino beam flux in the T2K neutrino oscillation experiment as well as for more reliable simulations of cosmic-ray air showers. Moreover, p+p, p+Pb and nucleus+nucleus collisions will be studied extensively to allow for a study of properties of the onset of deconfinement and search for the critical point of strongly interacting matter. Currently NA61/SHINE uses the old NA49 software framework for reconstruction, simulation and data analysis. The core of this legacy framework was developed in the early 1990s. It is written in different programming and scripting languages (C, pgi-Fortran, shell) and provides several concurrent data formats for the event data model, which includes also obsolete parts. In this contribution we will introduce the new software framework, called Shine, that is written in C++ and designed to comprise three principal parts: a collection of processing modules which can be assembled and sequenced by the user via XML files, an event data model which contains all simulation and reconstruction information based on STL and ROOT streaming, and a detector description which provides data on the configuration and state of the experiment. To assure a quick migration to the Shine framework, wrappers were introduced that allow to run legacy code parts as modules in the new framework and we will present first results on the cross validation of the two frameworks.
Shine: still a glittering moment, or now a little bit tarnished?
Welch, Mark
2007-06-01
The representation of mental illness in the cinema has a long and varied history. Each film emerges from a cultural context and understanding of psychopathology and some landmark films have made a profound impact on the way in which psychiatric disorders are regarded by the general public. One prime example is Shine, produced in 1996 and based on the life of David Helfgott, a child musical prodigy who later developed a severe mental illness. However, although the film garnered numerous awards and public acclaim, its premises have been questioned and the explanatory model of mental illness that it promotes has been criticized. This paper examines the cultural forces that shape cinematic representations and the example of Shine in particular.
The Small Acceptance Vertex Detector of NA61/SHINE
NASA Astrophysics Data System (ADS)
Deveaux, M.; Aduszkiewicz, A.; Ali, Y.; Baszczyk, M.; Brylinski, W.; Dorosz, P.; Di Luise, S.; Feofilov, G.; Gazdzicki, M.; Igolkin, S.; Jablonski, M.; Kovalenko, V.; Koziel, M.; Kucewicz, W.; Larsen, D.; Lazareva, T.; Martinengo, P.; Merzlaya, A.; Mik, L.; Planeta, R.; Snoch, A.; Vechernin, V.; Tefelski, D.; Suljic, M.; Staszel, P.
2018-02-01
Charmonium production in heavy ion collisions is considered as an important diagnostic probe for studying the phase diagram of strongly interacting matter for potential phase transitions. The interpretation of existing data from the CERN SPS is hampered by a lack of knowledge on the properties of open charm particle production in the fireball. Moreover, open charm production in heavy ion collisions by itself is poorly understood. To overcome this obstacle, the NA61/SHINE was equipped with a Small Acceptance Vertex Detector (SAVD), which is predicted to make the experiment sensitive to open charm mesons produced in A-A collisions at the SPS top energy. This paper will introduce the concept and the hardware of the SAVD. Moreover, first running experience as obtained in a commissioning run with a 150 AGeV/c Pb+Pb collision system will be reported.
Concealing a shiny facial skin appearance by an Aerogel-based formula. In vitro and in vivo studies.
Cassin, G; Diridollou, S; Flament, F; Adam, A S; Pierre, P; Colomb, L; Morancais, J L; Qiu, H
2018-02-01
To explore, in vitro and in vivo, the potential interest of an Aerogel-based formula, in concealing a naturally shiny facial skin. In vitro, various formulae and ingredients were applied as a thin film onto contrast plates and studied through measuring the shine induced following pump spraying of a mixture of oleic acid and mineral water as a sebum/sweat mix model. In such a test, an Aerogel ingredient led to very positive results. In vivo, two different formulae with various concentrations of Aerogel were randomly tested on half side of the face vs. bare side of Chinese women, under some provocative environmental conditions, known to enhance facial shine. These conditions comprised a normal activity under a hot and highly humid summer time followed - or not - by a hamam session. Both studies included comparative evaluations using a half-face procedure (treated/untreated or vehicle). In the first case, evaluations were quantitatively carried out, whereas the second one was based on a quantitative self-evaluations from standardized full-face photographs RESULTS: In vitro, the tested Aerogel, incorporated at 1% or 2% concentration in a common O/W cosmetic emulsion, shows an immediate light scattering effect, thereby masking shine. Such effect appears of much higher amplitude than that of two other tested particulate ingredients (Talc and Perlite). A noticeable remanence of anti-shine effect was confirmed in vivo in extreme conditions. The latter was self-perceived by all participants in the second study. This result is likely related to the super hydrophobic behaviour of the Aerogel. As cosmetic ingredient, this new Aerogel appears as a highly promising ingredient for concealing the facial skin shine, a source of complaint from many consumers living in hot and humid regions. © 2017 Society of Cosmetic Scientists and the Société Française de Cosmétologie.
Beyond Guzman? The Future of the Shining Path in Peru.
1992-12-01
racism , sexism , poverty, and joblessness, because the Fourth Sword has given them the answers to their situation-- and promises to change that situation...on Mao’s three-phased theory of protracted revolutionary warfare.- The Shining Path’s revolutionary ideology, although based on Maoism, is in reality... theory , and is similar in approach to Parsons’ four types of social control. See Talcott Parsons, "Reflections on the Place of Force in Social Process
NA61/SHINE facility at the CERN SPS: beams and detector system
NASA Astrophysics Data System (ADS)
Abgrall, N.; Andreeva, O.; Aduszkiewicz, A.; Ali, Y.; Anticic, T.; Antoniou, N.; Baatar, B.; Bay, F.; Blondel, A.; Blumer, J.; Bogomilov, M.; Bogusz, M.; Bravar, A.; Brzychczyk, J.; Bunyatov, S. A.; Christakoglou, P.; Cirkovic, M.; Czopowicz, T.; Davis, N.; Debieux, S.; Dembinski, H.; Diakonos, F.; Di Luise, S.; Dominik, W.; Drozhzhova, T.; Dumarchez, J.; Dynowski, K.; Engel, R.; Efthymiopoulos, I.; Ereditato, A.; Fabich, A.; Feofilov, G. A.; Fodor, Z.; Fulop, A.; Gaździcki, M.; Golubeva, M.; Grebieszkow, K.; Grzeszczuk, A.; Guber, F.; Haesler, A.; Hasegawa, T.; Hierholzer, M.; Idczak, R.; Igolkin, S.; Ivashkin, A.; Jokovic, D.; Kadija, K.; Kapoyannis, A.; Kaptur, E.; Kielczewska, D.; Kirejczyk, M.; Kisiel, J.; Kiss, T.; Kleinfelder, S.; Kobayashi, T.; Kolesnikov, V. I.; Kolev, D.; Kondratiev, V. P.; Korzenev, A.; Koversarski, P.; Kowalski, S.; Krasnoperov, A.; Kurepin, A.; Larsen, D.; Laszlo, A.; Lyubushkin, V. V.; Maćkowiak-Pawłowska, M.; Majka, Z.; Maksiak, B.; Malakhov, A. I.; Maletic, D.; Manglunki, D.; Manic, D.; Marchionni, A.; Marcinek, A.; Marin, V.; Marton, K.; Mathes, H.-J.; Matulewicz, T.; Matveev, V.; Melkumov, G. L.; Messina, M.; Mrówczyński, St.; Murphy, S.; Nakadaira, T.; Nirkko, M.; Nishikawa, K.; Palczewski, T.; Palla, G.; Panagiotou, A. D.; Paul, T.; Peryt, W.; Petukhov, O.; Pistillo, C.; Płaneta, R.; Pluta, J.; Popov, B. A.; Posiadala, M.; Puławski, S.; Puzovic, J.; Rauch, W.; Ravonel, M.; Redij, A.; Renfordt, R.; Richter-Was, E.; Robert, A.; Röhrich, D.; Rondio, E.; Rossi, B.; Roth, M.; Rubbia, A.; Rustamov, A.; Rybczyński, M.; Sadovsky, A.; Sakashita, K.; Savic, M.; Schmidt, K.; Sekiguchi, T.; Seyboth, P.; Sgalaberna, D.; Shibata, M.; Sipos, R.; Skrzypczak, E.; Słodkowski, M.; Sosin, Z.; Staszel, P.; Stefanek, G.; Stepaniak, J.; Stroebele, H.; Susa, T.; Szuba, M.; Tada, M.; Tereshchenko, V.; Tolyhi, T.; Tsenov, R.; Turko, L.; Ulrich, R.; Unger, M.; Vassiliou, M.; Veberic, D.; Vechernin, V. V.; Vesztergombi, G.; Vinogradov, L.; Wilczek, A.; Włodarczyk, Z.; Wojtaszek-Szwarz, A.; Wyszyński, O.; Zambelli, L.; Zipper, W.
2014-06-01
NA61/SHINE (SPS Heavy Ion and Neutrino Experiment) is a multi-purpose experimental facility to study hadron production in hadron-proton, hadron-nucleus and nucleus-nucleus collisions at the CERN Super Proton Synchrotron. It recorded the first physics data with hadron beams in 2009 and with ion beams (secondary 7Be beams) in 2011. NA61/SHINE has greatly profited from the long development of the CERN proton and ion sources and the accelerator chain as well as the H2 beamline of the CERN North Area. The latter has recently been modified to also serve as a fragment separator as needed to produce the Be beams for NA61/SHINE. Numerous components of the NA61/SHINE set-up were inherited from its predecessors, in particular, the last one, the NA49 experiment. Important new detectors and upgrades of the legacy equipment were introduced by the NA61/SHINE Collaboration. This paper describes the state of the NA61/SHINE facility — the beams and the detector system — before the CERN Long Shutdown I, which started in March 2013.
Tycho's Star Shines in Gamma Rays
2017-12-08
NASA image relase December 13, 2011 Gamma-rays detected by Fermi's LAT show that the remnant of Tycho's supernova shines in the highest-energy form of light. This portrait of the shattered star includes gamma rays (magenta), X-rays (yellow, green, and blue), infrared (red) and optical data. Credit: Gamma ray, NASA/DOE/Fermi LAT Collaboration; X-ray, NASA/CXC/SAO; Infrared, NASA/JPL-Caltech; Optical, MPIA, Calar Alto, O. Krause et al. and DSS To read more go to: www.nasa.gov/mission_pages/GLAST/news/tycho-star.html NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
The Shining Path: The Successful Blending of Mao and Mariategui in Peru
1992-06-05
the textbook models such that those familiar with the situation are unsure as to the current balance of forces and how the Peruvian government... familiar with the power of the Shining Path. The growth of the Shining Path in Lima and in the Upper Huallaga Valley is connected. By 1987 the Shining...California Press, 1972. Rojas Samanez, Alvaro, and Ouillermo Blanco Woolcott, ed. Sendero de Violencia : Testimonios Periodisticos 1980- 1989
Cortical dynamics of figure-ground segmentation: shine-through.
Francis, Gregory
2009-01-01
The shine-through effect occurs when a brief offset vernier target is followed by a grating of non-offset vernier elements. Rather than mask the target, this stimulus sequence produces a percept of the target vernier occluding the mask elements. We analyzed the dynamics of the 3D LAMINART model of depth perception and found that it explains the appearance of shine-through for these stimuli. The model explanation proposes that shine-through is due to a combination of false binocular disparity matches between the target and the central element of the mask, and a weakening of between disparity competition due to spatial competition and boundary grouping. Simulations of the model demonstrate that its behavior closely matches empirical data on the properties of shine-through. The model is contrasted with an alternative explanation of shine-through, and novel mask conditions are studied that allow for empirical tests of the model hypotheses.
FY13 Progress Report on the Phase I Mini-SHINE Water Irradiations and Micro-SHINE Irradiations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Youker, Amanda J.; Krebs, John F.; Kalensky, Michael
2014-02-19
The original goal of the micro-SHINE experiments was to confirm that precipitation of uranyl peroxide can be prevented by adding a catalyst such as FeSO 4 to destroy peroxide. After successfully demonstrating that FeSO 4 is an effective catalyst for peroxide destruction, subsequent micro-SHINE solutions were used as tracers to perform a Mo-separation and recovery column experiment, a sulfate-to-nitrate conversion, and iodine speciation experiments.
The Fallacy of Leadership Removal Strategies in 21st Century Counterinsurgency
2011-06-18
Kathryn Gregory, "Shining Path, Tupac Amaru (Peru, leftists)," Council on Foreign Relations, August 27, 2009, http://www.cfr.org/terrorism/shining-path... tupac -amaru-peru-leftists/p9276 (accessed November 28, 2010) 51 are still present and in 2008 alone they executed 64 attacks, killing police...34Shining Path, Tupac Amaru (Peru, leftists)." Council of Foreign Relations. August 27, 2009. http://www.cfr.org/terrorism/shining-path- tupac - amaru-peru
Incorporating partial shining effects in proton pencil-beam dose calculation
NASA Astrophysics Data System (ADS)
Li, Yupeng; Zhang, Xiaodong; Fwu Lii, Ming; Sahoo, Narayan; Zhu, Ron X.; Gillin, Michael; Mohan, Radhe
2008-02-01
A range modulator wheel (RMW) is an essential component in passively scattered proton therapy. We have observed that a proton beam spot may shine on multiple steps of the RMW. Proton dose calculation algorithms normally do not consider the partial shining effect, and thus overestimate the dose at the proximal shoulder of spread-out Bragg peak (SOBP) compared with the measurement. If the SOBP is adjusted to better fit the plateau region, the entrance dose is likely to be underestimated. In this work, we developed an algorithm that can be used to model this effect and to allow for dose calculations that better fit the measured SOBP. First, a set of apparent modulator weights was calculated without considering partial shining. Next, protons spilled from the accelerator reaching the modulator wheel were simplified as a circular spot of uniform intensity. A weight-splitting process was then performed to generate a set of effective modulator weights with the partial shining effect incorporated. The SOBPs of eight options, which are used to label different combinations of proton-beam energy and scattering devices, were calculated with the generated effective weights. Our algorithm fitted the measured SOBP at the proximal and entrance regions much better than the ones without considering partial shining effect for all SOBPs of the eight options. In a prostate patient, we found that dose calculation without considering partial shining effect underestimated the femoral head and skin dose.
Colleges as Shining Cities on a Hill
ERIC Educational Resources Information Center
Townsend, Kathleen Kennedy
2012-01-01
In this article, the author proposes that the notion of America be reintroduced as the "shining city on a hill," that abiding image from American history. The image of the shining city on a hill captures the imagination because it reflects the abiding truth that people become fully human in society, not outside of it. People need one…
Looking for the Phase Transition—Recent NA61/SHINE Results
NASA Astrophysics Data System (ADS)
Turko, Ludwik
2018-03-01
The fixed-target NA61/SHINE experiment (SPS CERN) looks for the critical point of strongly interacting matter and the properties of the onset of deconfinement. It is a two dimensional scan of measurements of particle spectra and fluctuations in proton-proton, proton-nucleus and nucleus-nucleus interactions as a function of collision energy and system size, corresponding to a two dimensional phase diagram (temperature T - baryonic chemical potential $\\mu_B$). New NA61/SHINE results are presented here, such as transverse momentum and multiplicity fluctuations in Ar+Sc collisions compared to NA61/SHINE p+p and Be+Be data, as well as to earlier NA49 A+A results. Recently, a preliminary signature for the new size dependent effect - rapid changes in system size dependence was observed in NA61-SHINE data, labeled as percolation threshold or onset of fireball. This would be closely related to the vicinity of the hadronic phase transition region.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stepinski, Dominique C.; Vandegrift, G. F.
2015-09-30
Argonne is assisting SHINE Medical Technologies (SHINE) in their efforts to develop SHINE, an accelerator-driven process that will utilize a uranyl-sulfate solution for the production of fission product Mo-99. An integral part of the process is the development of a column for the separation and recovery of Mo-99, followed by a concentration column to reduce the product volume from 15-25 L to <1 L. Argonne has collected data from batch studies and breakthrough column experiments to utilize the VERSE (Versatile Reaction Separation) simulation program (Purdue University) to design plant-scale product recovery and concentration processes.
Chabala, Chishala; Turkova, Anna; Thomason, Margaret J; Wobudeya, Eric; Hissar, Syed; Mave, Vidya; van der Zalm, Marieke; Palmer, Megan; Kapasa, Monica; Bhavani, Perumal K; Balaji, Sarath; Raichur, Priyanka A; Demers, Anne-Marie; Hoddinott, Graeme; Owen-Powell, Ellen; Kinikar, Aarti; Musoke, Philippa; Mulenga, Veronica; Aarnoutse, Rob; McIlleron, Helen; Hesseling, Anneke; Crook, Angela M; Cotton, Mark; Gibb, Diana M
2018-04-19
Tuberculosis (TB) in children is frequently paucibacillary and non-severe forms of pulmonary TB are common. Evidence for tuberculosis treatment in children is largely extrapolated from adult studies. Trials in adults with smear-negative tuberculosis suggest that treatment can be effectively shortened from 6 to 4 months. New paediatric, fixed-dose combination anti-tuberculosis treatments have recently been introduced in many countries, making the implementation of World Health Organisation (WHO)-revised dosing recommendations feasible. The safety and efficacy of these higher drug doses has not been systematically assessed in large studies in children, and the pharmacokinetics across children representing the range of weights and ages should be confirmed. SHINE is a multicentre, open-label, parallel-group, non-inferiority, randomised controlled, two-arm trial comparing a 4-month vs the standard 6-month regimen using revised WHO paediatric anti-tuberculosis drug doses. We aim to recruit 1200 African and Indian children aged below 16 years with non-severe TB, with or without HIV infection. The primary efficacy and safety endpoints are TB disease-free survival 72 weeks post randomisation and grade 3 or 4 adverse events. Nested pharmacokinetic studies will evaluate anti-tuberculosis drug concentrations, providing model-based predictions for optimal dosing, and measure antiretroviral exposures in order to describe the drug-drug interactions in a subset of HIV-infected children. Socioeconomic analyses will evaluate the cost-effectiveness of the intervention and social science studies will further explore the acceptability and palatability of these new paediatric drug formulations. Although recent trials of TB treatment-shortening in adults with sputum-positivity have not been successful, the question has never been addressed in children, who have mainly paucibacillary, non-severe smear-negative disease. SHINE should inform whether treatment-shortening of drug-susceptible TB in children, regardless of HIV status, is efficacious and safe. The trial will also fill existing gaps in knowledge on dosing and acceptability of new anti-tuberculosis formulations and commonly used HIV drugs in settings with a high burden of TB. A positive result from this trial could simplify and shorten treatment, improve adherence and be cost-saving for many children with TB. Recruitment to the SHINE trial begun in July 2016; results are expected in 2020. International Standard Randomised Controlled Trials Number: ISRCTN63579542 , 14 October 2014. Pan African Clinical Trials Registry Number: PACTR201505001141379 , 14 May 2015. Clinical Trial Registry-India, registration number: CTRI/2017/07/009119, 27 July 2017.
SHINE: Strategic Health Informatics Networks for Europe.
Kruit, D; Cooper, P A
1994-10-01
The mission of SHINE is to construct an open systems framework for the development of regional community healthcare telematic services that support and add to the strategic business objectives of European healthcare providers and purchasers. This framework will contain a Methodology, that identifies healthcare business processes and develops a supporting IT strategy, and the Open Health Environment. This consists of an architecture and information standards that are 'open' and will be available to any organisation wishing to construct SHINE conform regional healthcare telematic services. Results are: generic models, e.g., regional healthcare business networks, IT strategies; demonstrable, e.g., pilot demonstrators, application and service prototypes; reports, e.g., SHINE Methodology, pilot specifications & evaluations; proposals, e.g., service/interface specifications, standards conformance.
Ares I-X Ground Diagnostic Prototype
NASA Technical Reports Server (NTRS)
Schwabacher, Mark A.; Martin, Rodney Alexander; Waterman, Robert D.; Oostdyk, Rebecca Lynn; Ossenfort, John P.; Matthews, Bryan
2010-01-01
The automation of pre-launch diagnostics for launch vehicles offers three potential benefits: improving safety, reducing cost, and reducing launch delays. The Ares I-X Ground Diagnostic Prototype demonstrated anomaly detection, fault detection, fault isolation, and diagnostics for the Ares I-X first-stage Thrust Vector Control and for the associated ground hydraulics while the vehicle was in the Vehicle Assembly Building at Kennedy Space Center (KSC) and while it was on the launch pad. The prototype combines three existing tools. The first tool, TEAMS (Testability Engineering and Maintenance System), is a model-based tool from Qualtech Systems Inc. for fault isolation and diagnostics. The second tool, SHINE (Spacecraft Health Inference Engine), is a rule-based expert system that was developed at the NASA Jet Propulsion Laboratory. We developed SHINE rules for fault detection and mode identification, and used the outputs of SHINE as inputs to TEAMS. The third tool, IMS (Inductive Monitoring System), is an anomaly detection tool that was developed at NASA Ames Research Center. The three tools were integrated and deployed to KSC, where they were interfaced with live data. This paper describes how the prototype performed during the period of time before the launch, including accuracy and computer resource usage. The paper concludes with some of the lessons that we learned from the experience of developing and deploying the prototype.
Dixon, Brian E; Kaneshiro, Kellie
2012-01-01
Human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) remains a significant international public health challenge. The Statewide HIV/AIDS Information Network (SHINE) Project was created to improve HIV/AIDS health information use and access for health care professionals, patients, and affected communities in Indiana. Our objective was to assess the information-seeking behaviors of health care professionals and consumers who seek information on the testing, treatment, and management of HIV/AIDS and the usability of the SHINE Project's resources in meeting end user needs. The feedback was designed to help SHINE Project members improve and expand the SHINE Project's online resources. A convenience sample of health care professionals and consumers participated in a usability study. Participants were asked to complete typical HIV/AIDS information-seeking tasks using the SHINE Project website. Feedback was provided in the form of standardized questionnaire and usability "think-aloud" responses. Thirteen participants took part in the usability study. Clinicians generally reported the site to be "very good," while consumers generally found it to be "good." Health care professionals commented that they lack access to comprehensive resources for treating patients with HIV/AIDS. They requested new electronic resources that could be integrated in clinical practice and existing information technology infrastructures. Consumers found the SHINE website and its collected information resources overwhelming and difficult to navigate. They requested simpler, multimedia-content rich resources to deliver information on HIV/AIDS testing, treatment, and disease management. Accessibility, usability, and user education remain important challenges that public health and information specialists must address when developing and deploying interventions intended to empower consumers and support coordinated, patient-centric care.
NASA Astrophysics Data System (ADS)
Pahud, D. M.; Niembro, T.
2014-12-01
The SHINE workshop is an annual meeting of solar and heliospheric scientists which, in addition to aiming to improve understanding of solar disturbances and their propagation to, and effect, on the Earth (shinecon.org), is dedicated to actively supporting students. This dedication is substantiated in part through the National Science Foundation (NSF) providing funding for student attendance to the workshop, which enables student participation. Another example of SHINE's commitment to its student members is the incorporation of a Student Day prior to the workshop since 2003, entirely organized and run by two student representatives. While there are variations in format from year to year, Student Day consists of tutorials and research talks exclusively by student volunteers to an audience of only students. The day is intended to provide a low-stress environment for students to learn about the various topics addressed during the workshop, to ask questions freely, and to engage in scientific discussion with other students which hopefully is a catalyst for collaboration. As a result of positive experiences, over the past decade student attendance and participation in the workshop have increased. At the SHINE 2014 workshop, nearly a third of attendees were students. SHINE student visibility has increased over the years, with student posters being advertised at breakfast, inclusion of a student day summary by the student representatives during a plenary session, and continued support from the steering committee. Students are also promoting a broader impact of SHINE sciences via increased social media presence. From a student representative's perspective, SHINE has built and fostered a healthy student community and encourages students to engage in shaping the future of the field.
The Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial: Rationale, Design, and Methods.
Humphrey, Jean H; Jones, Andrew D; Manges, Amee; Mangwadu, Goldberg; Maluccio, John A; Mbuya, Mduduzi N N; Moulton, Lawrence H; Ntozini, Robert; Prendergast, Andrew J; Stoltzfus, Rebecca J; Tielsch, James M
2015-12-15
Child stunting and anemia are intractable public health problems in developing countries and have profound short- and long-term consequences. The Sanitation Hygiene Infant Nutrition Efficacy (SHINE) trial is motivated by the premise that environmental enteric dysfunction (EED) is a major underlying cause of both stunting and anemia, that chronic inflammation is the central characteristic of EED mediating these adverse effects, and that EED is primarily caused by high fecal ingestion due to living in conditions of poor water, sanitation, and hygiene (WASH). SHINE is a proof-of-concept, 2 × 2 factorial, cluster-randomized, community-based trial in 2 rural districts of Zimbabwe that will test the independent and combined effects of protecting babies from fecal ingestion (factor 1, operationalized through a WASH intervention) and optimizing nutritional adequacy of infant diet (factor 2, operationalized through an infant and young child feeding [IYCF] intervention) on length and hemoglobin at 18 months of age. Within SHINE we will measure 2 causal pathways. The program impact pathway comprises the series of processes and behaviors linking implementation of the interventions with the 2 child health primary outcomes; it will be modeled using measures of fidelity of intervention delivery and household uptake of promoted behaviors and practices. We will also measure a range of household and individual characteristics, social interactions, and maternal capabilities for childcare, which we hypothesize will explain heterogeneity along these pathways. The biomedical pathway comprises the infant biologic responses to the WASH and IYCF interventions that ultimately result in attained stature and hemoglobin concentration at 18 months of age; it will be elucidated by measuring biomarkers of intestinal structure and function (inflammation, regeneration, absorption, and permeability); microbial translocation; systemic inflammation; and hormonal determinants of growth and anemia among a subgroup of infants enrolled in an EED substudy. This article describes the rationale, design, and methods underlying the SHINE trial. NCT01824940. © The Author 2015. Published by Oxford University Press for the Infectious Diseases Society of America.
Fusing Symbolic and Numerical Diagnostic Computations
NASA Technical Reports Server (NTRS)
James, Mark
2007-01-01
X-2000 Anomaly Detection Language denotes a developmental computing language, and the software that establishes and utilizes the language, for fusing two diagnostic computer programs, one implementing a numerical analysis method, the other implementing a symbolic analysis method into a unified event-based decision analysis software system for realtime detection of events (e.g., failures) in a spacecraft, aircraft, or other complex engineering system. The numerical analysis method is performed by beacon-based exception analysis for multi-missions (BEAMs), which has been discussed in several previous NASA Tech Briefs articles. The symbolic analysis method is, more specifically, an artificial-intelligence method of the knowledge-based, inference engine type, and its implementation is exemplified by the Spacecraft Health Inference Engine (SHINE) software. The goal in developing the capability to fuse numerical and symbolic diagnostic components is to increase the depth of analysis beyond that previously attainable, thereby increasing the degree of confidence in the computed results. In practical terms, the sought improvement is to enable detection of all or most events, with no or few false alarms.
NASA Tech Briefs, October 2008
NASA Technical Reports Server (NTRS)
2008-01-01
Topics covered include: Control Architecture for Robotic Agent Command and Sensing; Algorithm for Wavefront Sensing Using an Extended Scene; CO2 Sensors Based on Nanocrystalline SnO2 Doped with CuO; Improved Airborne System for Sensing Wildfires; VHF Wide-Band, Dual-Polarization Microstrip-Patch Antenna; Onboard Data Processor for Change-Detection Radar Imaging; Using LDPC Code Constraints to Aid Recovery of Symbol Timing; System for Measuring Flexing of a Large Spaceborne Structure; Integrated Formation Optical Communication and Estimation System; Making Superconducting Welds between Superconducting Wires; Method for Thermal Spraying of Coatings Using Resonant-Pulsed Combustion; Coating Reduces Ice Adhesion; Hybrid Multifoil Aerogel Thermal Insulation; SHINE Virtual Machine Model for In-flight Updates of Critical Mission Software; Mars Image Collection Mosaic Builder; Providing Internet Access to High-Resolution Mars Images; Providing Internet Access to High-Resolution Lunar Images; Expressions Module for the Satellite Orbit Analysis Program Virtual Satellite; Small-Body Extensions for the Satellite Orbit Analysis Program (SOAP); Scripting Module for the Satellite Orbit Analysis Program (SOAP); XML-Based SHINE Knowledge Base Interchange Language; Core Technical Capability Laboratory Management System; MRO SOW Daily Script; Tool for Inspecting Alignment of Twinaxial Connectors; An ATP System for Deep-Space Optical Communication; Polar Traverse Rover Instrument; Expert System Control of Plant Growth in an Enclosed Space; Detecting Phycocyanin-Pigmented Microbes in Reflected Light; DMAC and NMP as Electrolyte Additives for Li-Ion Cells; Mass Spectrometer Containing Multiple Fixed Collectors; Waveguide Harmonic Generator for the SIM; Whispering Gallery Mode Resonator with Orthogonally Reconfigurable Filter Function; Stable Calibration of Raman Lidar Water-Vapor Measurements; Bimaterial Thermal Compensators for WGM Resonators; Root Source Analysis/ValuStream[Trade Mark] - A Methodology for Identifying and Managing Risks; Ensemble: an Architecture for Mission-Operations Software; Object Recognition Using Feature-and Color-Based Methods; On-Orbit Multi-Field Wavefront Control with a Kalman Filter; and The Interplanetary Overlay Networking Protocol Accelerator.
Software Analyzes Complex Systems in Real Time
NASA Technical Reports Server (NTRS)
2008-01-01
Expert system software programs, also known as knowledge-based systems, are computer programs that emulate the knowledge and analytical skills of one or more human experts, related to a specific subject. SHINE (Spacecraft Health Inference Engine) is one such program, a software inference engine (expert system) designed by NASA for the purpose of monitoring, analyzing, and diagnosing both real-time and non-real-time systems. It was developed to meet many of the Agency s demanding and rigorous artificial intelligence goals for current and future needs. NASA developed the sophisticated and reusable software based on the experience and requirements of its Jet Propulsion Laboratory s (JPL) Artificial Intelligence Research Group in developing expert systems for space flight operations specifically, the diagnosis of spacecraft health. It was designed to be efficient enough to operate in demanding real time and in limited hardware environments, and to be utilized by non-expert systems applications written in conventional programming languages. The technology is currently used in several ongoing NASA applications, including the Mars Exploration Rovers and the Spacecraft Health Automatic Reasoning Pilot (SHARP) program for the diagnosis of telecommunication anomalies during the Neptune Voyager Encounter. It is also finding applications outside of the Space Agency.
Align-and-shine photolithography
NASA Astrophysics Data System (ADS)
Petrusis, Audrius; Rector, Jan H.; Smith, Kristen; de Man, Sven; Iannuzzi, Davide
2009-10-01
At the beginning of 2009, our group has introduced a new technique that allows fabrication of photolithographic patterns on the cleaved end of an optical fibre: the align-and-shine photolithography technique (see A. Petrušis et al., "The align-and-shine technique for series production of photolithography patterns on optical fibres", J. Micromech. Microeng. 19, 047001, 2009). Align-and-shine photolithography combines standard optical lithography with imagebased active fibre alignment processes. The technique adapts well to series production, opening the way to batch fabrication of fibre-top devices (D. Iannuzzi et al., "Monolithic fibre-top cantilever for critical environments and standard applications", Appl. Phys. Lett. 88, 053501, 2006) and all other devices that rely on suitable machining of engineered parts on the tip of a fibre. In this paper we review our results and briefly discuss its potential applications.
SHINE and Mini-SHINE Column Designs for Recovery of Mo from 140 g-U/L Uranyl Sulfate
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stepinski, Dominique C.; Vandegrift, George F.
Argonne is assisting SHINE Medical Technologies (SHINE) in their efforts to develop an accelerator-driven process that utilizes a uranyl-sulfate solution for the production of fission Mo-99. In an effort to design a Mo-recovery system for the SHINE project using low-enriched uranium (LEU), we conducted batch, breakthrough, and pulse tests to determine the Mo isotherm, mass-transfer zone (MTZ), and system parameters for a 130 g-U/L uranyl sulfate solution at pH 1 and 80°C, as described previously. The VERSE program was utilized to calculate the MTZ under various loading times and velocities. The results were then used to design Mo separation andmore » recovery columns employing a pure titania sorbent (110-μm particles, S110, and 60 Å pore size). The plant-scale column designs assume Mo will be separated from 271 L of a 141 g-U/L uranyl sulfate solution, pH 1, containing 0.0023 mM Mo. The VERSE-designed recovery systems have been tested and verified in laboratory-scale experiments, and this approach was found to be very successful.« less
Micro-SHINE Uranyl Sulfate Irradiations at the Linac
DOE Office of Scientific and Technical Information (OSTI.GOV)
Youker, Amanda J.; Kalensky, Michael; Chemerisov, Sergey
2016-08-01
Peroxide formation due to water radiolysis in a uranyl sulfate solution is a concern for the SHINE Medical Technologies process in which Mo-99 is generated from the fission of dissolved low enriched uranium. To investigate the effects of power density and fission on peroxide formation and uranyl-peroxide precipitation, uranyl sulfate solutions were irradiated using a 50-MeV electron linac as part of the micro-SHINE experimental setup. Results are given for uranyl sulfate solutions with both high and low enriched uranium irradiated at different linac powers.
Shining a New Light on Silicon PV Manufacturing - Continuum Magazine |
lines. Photo by Dennis Schroeder, NREL Shining a New Light on Silicon PV Manufacturing Groundbreaking system and can be automatically eliminated. Photo by Dennis Schroeder, NREL Tackling the Serious Issue of
Charged pion spectra in proton—carbon interactions at 31 GeV/c
NASA Astrophysics Data System (ADS)
Zofia Posiadała, Magdalena; NA61/SHINE Collaboration
2013-02-01
The NA61/SHINE experiment at CERN SPS measured charged pion spectra in p+C interactions at 31 GeV/c. These measurements are necessary to improve predictions of the neutrino flux for the T2K long baseline neutrino oscillation experiment in Japan. Presented analysis was based on the data collected during the first NA61/SHINE run in 2007 with an isotropic graphite target with a thickness of 4% of nuclear interaction length. Three different methods which were used in order to obtain π+ and π- spectra are introduced. Differential cross sections for negatively and positively charged pions are presented as a function of laboratory momentum in ten intervals of the laboratory polar angle up to 420 mrad.
TV Star Jim Parsons Shines Light on NIH Research | NIH MedlinePlus the Magazine
... TV Star Jim Parsons Shines Light on NIH Research Documentary highlights key sickle cell and cancer trials ... Americans about the investment we make in medical research through NIH? As taxpayers whose money helps fund ...
Violation of geometrical scaling in pp collisions at NA61/SHINE
NASA Astrophysics Data System (ADS)
Praszalowicz, Michal
2013-04-01
We analyze geometrical scaling (GS) of negative pion multiplicity pT distributions at NA61/SHINE energies. We show that even though NA61/SHINE energies are low, one may expect to find GS in the particle spectra. We argue that qualitative behavior of ratios of multiplicities at different energies is in agreement with a simple picture of GS which is violated for pT smaller than some nonperturbative scale Λ and when larger Bjorken x of one of the scattering patrons crosses xmax above which a gluonic cloud becomes dilute and quark degrees of freedom become important.
Cao, Wu-lin; Meng, Xiang-cai; Ma, Wei
2015-09-01
In order to search for a new pathway to improve the yield of ginseng through growing at the full sun shine accompanied by salicylic acid (SA), the net photosynthetic rate (P(n)), superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), malondialdehyde (MDA) in Panax ginseng leaves, and the content of ginsenosides in roots were compared under various concentrations of SA and full sun shine with the traditional shade shed. Under the full sun shine, 0.05, 0.2 mmol x L(-1) SA increased net photosynthetic rate to a great extent. Under the cloudy day, the average net photosynthetic rate increased by 127.8% and 155.0% over the traditional shade shed, 13.9% and 27.5% over the treatment without SA respectively; under the clear day, 23.5% and 30.4% over the traditional shade shed, 8.6% and 14.6% over the treatment without SA, particularly obvious in the morning and late afternoon. With such concentration, SA increased activities of SOD, CAT, POD, and decreased the contents of the MDA. This difference resulted from different light intensity, rise of light saturation point, and fall of compensation point. Full sun shine decreased ginsenosides contents, but with SA, the ginsenosides regained, the content of Rg1 and Re, Rb1, total six types of ginsenosides in SA 0.2 mmol x L(-1) group were higher than those in the control group (P < 0.05) and other groups. The application of 0.2 mmol x L(-1) SA under full sun shine during a short time has little threat to the P. ginseng in spring, and could enhance the resistance to the adversity, which would improve the yield of ginseng heavily.
Noteworthy Articles in 2015 for the Cardiothoracic Anesthesiologist.
Varelmann, Dirk J; Muehlschlegel, J Daniel
2016-03-01
Large multicenter, randomized controlled trials published in reputable journals had a large impact on the world of cardiothoracic anesthesia in 2015. We as cardiac anesthesiologists pride ourselves as being experts in applied physiology, physics, ultrasonography, and pharmacology/pharmacotherapy. The selected studies added to our knowledge in the fields of echocardiography, pharmacology, molecular biology, and genetics. Outcome studies shine a light on important topics that are relevant to all cardiac anesthesiologists: does surgical atrial fibrillation ablation during mitral valve surgery reduce the recurrence of atrial fibrillation at 1 year after surgery? Does remote ischemic preconditioning live up to its promise to reduce postoperative major cardiac and cerebral events? Although we still do not have the answer to all the questions, the year 2015 has been a great step toward the goal of understanding molecular mechanisms of ischemic myocardial injury and toward providing evidence-based medicine for improving patient outcome. © The Author(s) 2016.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aduszkiewicz, A.; Ali, Y.; Andronov, E.
Measurements of inclusive spectra and mean multiplicities ofmore » $$\\pi^\\pm$$, K$$^\\pm$$, p and $$\\bar{\\textrm{p}}$$ produced in inelastic p+p interactions at incident projectile momenta of 20, 31, 40, 80 and 158 GeV/c ($$\\sqrt{s} = $$ 6.3, 7.7, 8.8, 12.3 and 17.3 GeV, respectively) were performed at the CERN Super Proton Synchrotron using the large acceptance NA61/SHINE hadron spectrometer. Spectra are presented as function of rapidity and transverse momentum and are compared to predictions of current models. The measurements serve as the baseline in the NA61/SHINE study of the properties of the onset of deconfinement and search for the critical point of strongly interacting matter.« less
ERIC Educational Resources Information Center
Koubek, Edward
1985-01-01
Outlines a demonstration involving weak acids and bases in aqueous solutions. A standard conductivity demonstration with a solution of acetic acid yields a barely glowing light bulb; a similar result occurs with ammonia solution. However, the bulb glows brightly when the solutions are mixed. (DH)
Nguyen, Kieu T H; Adamkiewicz, Marta A; Hebert, Lauren E; Zygiel, Emily M; Boyle, Holly R; Martone, Christina M; Meléndez-Ríos, Carola B; Noren, Karen A; Noren, Christopher J; Hall, Marilena Fitzsimons
2014-10-01
A target-unrelated peptide (TUP) can arise in phage display selection experiments as a result of a propagation advantage exhibited by the phage clone displaying the peptide. We previously characterized HAIYPRH, from the M13-based Ph.D.-7 phage display library, as a propagation-related TUP resulting from a G→A mutation in the Shine-Dalgarno sequence of gene II. This mutant was shown to propagate in Escherichia coli at a dramatically faster rate than phage bearing the wild-type Shine-Dalgarno sequence. We now report 27 additional fast-propagating clones displaying 24 different peptides and carrying 14 unique mutations. Most of these mutations are found either in or upstream of the gene II Shine-Dalgarno sequence, but still within the mRNA transcript of gene II. All 27 clones propagate at significantly higher rates than normal library phage, most within experimental error of wild-type M13 propagation, suggesting that mutations arise to compensate for the reduced virulence caused by the insertion of a lacZα cassette proximal to the replication origin of the phage used to construct the library. We also describe an efficient and convenient assay to diagnose propagation-related TUPS among peptide sequences selected by phage display. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.
Direct Down-scale Experiments of Concentration Column Designs for SHINE Process
DOE Office of Scientific and Technical Information (OSTI.GOV)
Youker, Amanda J.; Stepinski, Dominique C.; Vandegrift, George F.
Argonne is assisting SHINE Medical Technologies in their efforts to become a domestic Mo-99 producer. The SHINE accelerator-driven process uses a uranyl-sulfate target solution for the production of fission-product Mo-99. Argonne has developed a molybdenum recovery and purification process for this target solution. The process includes an initial Mo recovery column followed by a concentration column to reduce the product volume from 15-25 L to < 1 L prior to entry into the LEU Modified Cintichem (LMC) process for purification.1 This report discusses direct down-scale experiments of the plant-scale concentration column design, where the effects of loading velocity and temperaturemore » were investigated.« less
SHINING ROCK WILDERNESS, NORTH CAROLINA.
Lesure, Frank G.; Dunn, Maynard L.
1984-01-01
The Shining Rock Wilderness, in the Blue Ridge Mountains of Haywood County, North Carolina, is underlain by complexly folded mica gneiss and schist of Precambrian age. A mineral-resource survey determined that two commodities, quartz as a source of silica (SiO//2) and gneiss and schist suitable for common building stone and crushed rock, are present in large quantities. Demonstrated resources of silica occur at Shining Rock Mountain and small amounts of sheet muscovite (mica) and scrap mica are present at about 10 localities. Until deep drilling is done to test the results of the seismic studies, no estimate of the potential for gas can be made, but the presence of gas cannot be totally discounted.
NASA Astrophysics Data System (ADS)
Popov, Boris A.
2013-02-01
The HARP and NA61/SHINE hadroproduction experiments as well as their implications for neutrino physics are discussed. HARP measurements have already been used for predictions of neutrino beams in K2K and MiniBooNE/SciBooNE experiments and are also being used to improve the atmospheric neutrino flux predictions and to help in the optimization of neutrino factory and super-beam designs. First measurements released recently by the NA61/SHINE experiment are of significant importance for a precise prediction of the J-PARC neutrino beam used for the T2K experiment. Both HARP and NA61/SHINE experiments provide also a large amount of input for validation and tuning of hadron production models in Monte-Carlo generators.
Recent Results and the Future of the NA61/SHINE Strong Interactions Program
NASA Astrophysics Data System (ADS)
Łysakowski, B.
NA61/SHINE is a fixed target experiment at the CERN Super-Proton- Synchrotron. The main goals of the experiment are to discover the critical point of strongly interacting matter and study the properties of the onset of deconfnement. In order to reach these goals the collaboration studies hadron production properties in nucleus-nucleus, proton-proton and proton-nucleus interactions. In this talk, recent results on particle production in p+p interactions, as well as Be+Be and Ar+Sc collisions in the SPS energy range are reviewed. The results are compared with available world data. The future of the NA61/SHINE scientifc program is also presented.
Helping Students Rise and Shine
ERIC Educational Resources Information Center
Ross, Flynn; Gendron, Marcia; Nogar, Dan; Queen, Marjorie
2018-01-01
A high-poverty, previously low-performing elementary school in Maine shifted its from looking mainly at achievement and test scores to focusing on ways to create motivated, confident, engaged students. They created Rise and Shine, through which all 3rd-5th graders start each day with a fun, challenging activity chosen from a big menu--from…
NASA Astrophysics Data System (ADS)
Yamaji, T.; Yamazaki, T.; Tamasaku, K.; Namba, T.
2017-12-01
Single crystals have high atomic electric fields as much as 1 011 V /m , which correspond to magnetic fields of ˜103 T . These fields can be utilized to convert x-rays into axionlike particles (ALPs) coherently similar to x-ray diffraction. In this paper, we perform the first theoretical calculation of the Laue-case conversion in crystals based on the Darwin dynamical theory of x-ray diffraction. The calculation shows that the Laue-case conversion has longer interaction length than the Bragg case, and that ALPs in the keV range can be resonantly converted by tuning an incident angle of x-rays. ALPs with mass up to O (10 keV ) can be searched by light-shining-through-a-wall (LSW) experiments at synchrotron x-ray facilities.
Problem-Solving Test: Conditional Gene Targeting Using the Cre/loxP Recombination System
ERIC Educational Resources Information Center
Szeberényi, József
2013-01-01
Terms to be familiar with before you start to solve the test: gene targeting, knock-out mutation, bacteriophage, complementary base-pairing, homologous recombination, deletion, transgenic organisms, promoter, polyadenylation element, transgene, DNA replication, RNA polymerase, Shine-Dalgarno sequence, restriction endonuclease, polymerase chain…
No Child Left behind and the Insomnia Plague
ERIC Educational Resources Information Center
Mathis, William J.
2004-01-01
In 1974, Ronald Reagan called the United States a "shining city on a hill." A decade later, Mario Cuomo responded by speaking to us about another city that was not on a shining hill. His "Tale of Two Cities" speech, delivered at the 1984 Democratic National Convention, was not only moving but also haunting. In this other city…
JPRS Report, Soviet Union, International Affairs
1988-01-07
clouds are covered by a hardly noticeable golden crust and the road which has not yet managed to dry shines just like a roll of foil which has been...nearby. Or the muffled bark of a dog. Or the wail and pair of shining eyes of a jackal rummaging in search of food close to some small hamlet
SHINE for Girls: Innovating STEM Curriculum with Dance
ERIC Educational Resources Information Center
Hally, Tara; Sinha, Kirin
2018-01-01
SHINE for Girls, a nonprofit with the mission of empowering young women to value their own potential and capabilities within STEM fields, employs a unique curriculum that blends math with dance. They were selected as part of HundreED's 100 Global Education Innovations for 2017. In this article, Tara Hally, Director of Programming, and Kirin Sinha,…
News from the NA61/SHINE experiment
NASA Astrophysics Data System (ADS)
Šuša, Tatjana
2018-02-01
The main goals of the NA61/SHINE experiment at the CERN SPS are the search for the critical point of strongly interacting matter and the study of the properties of the onset of deconfinement. These aims are pursued by performing a two-dimensional scan of the phase diagram of strongly interacting matter by varying the momentum and size of the colliding nuclei. This contribution summarises the latest results from the NA61/SHINE experiment, in particular, new results on spectra and yields of ϕ meson in p+p interactions at 40, 80 and 158 GeV/c and K+ and K- production in central Be+Be collisions at mid-rapidity. In addition, results on system size dependence of particle yield ratios and fluctuations are presented.
News on mean pion multiplicity from NA61/SHINE
NASA Astrophysics Data System (ADS)
Naskręt, Michał
2018-02-01
NA61/SHINE is a large acceptance fixed target experiment at the CERN SPS which studies final hadronic states in interactions between various particles and nuclei [1]. The main topic of this contribution are preliminary results for mean negatively charged pion multiplicities 〈π-〉 from central Ar+Sc and Be+Be collisions. The data were taken recently by the NA61/SHINE collaboration for a wide range of beam momenta. Measured rapidity distributions were extrapolated to unmeasured regions to obtain total multiplicities 〈π-〉 A new scheme to calculate the mean number of wounded nucleons 〈W〉 utilizing the EPOS MC model is described. Using data from other experiments, a comparison of for different collisions and beam momenta is discussed.
In Memory of Garth Boomer: "May He Not 'Rust Unburnished' but 'Shine in Use'"
ERIC Educational Resources Information Center
Brock, Paul
2013-01-01
This article is based on the authors' own experience of Garth Boomer as a splendid friend, a superb colleague, and an inspirational leader. In September 2005 the author was invited to deliver the Garth Boomer Memorial Lecture at the Biennial International Conference of the Australian Curriculum Studies Association (ACSA). This article is based on…
Strategy Of Attrition: Why General Westmoreland Failed In 1967
2016-05-26
393-408; Neil Sheehan, A Bright Shining Lie: John Paul Vann and America in Vietnam (New York: Random House, 1988), 6. 1...March, James G, and Chip Heath . A Primer on Decision Making: How...Washington, DC: Office of Air Force History, 1988. Sheehan, Neil . A Bright Shining Lie: John Paul Vann and America in Vietnam. New York: Random House
Efficacy of antioxidants in human hair.
Fernández, Estibalitz; Martínez-Teipel, Blanca; Armengol, Ricard; Barba, Clara; Coderch, Luisa
2012-12-05
Hair is exposed every day to a range of harmful effects such as sunlight, pollution, cosmetic treatments, grooming practices and cleansing. The UV components of sunlight damage human hair, causing fibre degradation. UV-B attacks the melanin pigments and the protein fractions (keratin) of hair and UV-A produces free radical/reactive oxygen species (ROS) through the interaction of endogenous photosensitizers. Hair was dyed and the efficacy of two antioxidant formulations was demonstrated after UV exposure by evaluating, surface morphology, protein and amino acid degradation, lipidic peroxidation, colour and shine changes and strength/relaxation properties. UV treatment resulted in an increase in protein and lipid degradation, changes in colour and shine and in adverse consequences for the mechanical properties. Natural antioxidants obtained from artichoke and rice applied to pretreated hair improved mechanical properties and preserved colour and shine of fibres, coating them and protecting them against UV. Furthermore, the lipidic peroxidation of the protein degradation caused by UV was reduced for some treated fibres, suggesting an improvement in fibre integrity. This was more marked in the case of the fibres treated using the artichoke extract, whereas the rice extract was better preserving shine and colour of hair fibres. Copyright © 2012 Elsevier B.V. All rights reserved.
Jin, Weiyue; Xu, Xian; Jiang, Ling; Zhang, Zhidong; Li, Shuang; Huang, He
2015-11-01
Putative genes crtE, crtB, and crtI from Deinococcus wulumiqiensis R12, a novel species, were identified by genome mining and were co-expressed using the optimized Shine-Dalgarno (SD) regions to improve lycopene yield. A lycopene biosynthesis pathway was constructed by co-expressing these three genes in Escherichia coli. After optimizing the upstream SD regions and the culture medium, the recombinant strain EDW11 produced 88 mg lycopene g(-1) dry cell wt (780 mg lycopene l(-1)) after 40 h fermentation without IPTG induction, while the strain EDW without optimized SD regions only produced 49 mg lycopene g(-1) dry cell wt (417 mg lycopene l(-1)). Based on the optimization of the upstream SD regions and culture medium, the yield of the strain EDW11 reached a high level during microbial lycopene production until now.
A Volumetric Flask as a Projector
ERIC Educational Resources Information Center
Limsuwan, P.; Asanithi, P.; Thongpool, V.; Piriyawong, V.; Limsuwan, S.
2012-01-01
A lens based on liquid in the confined volume of a volumetric flask was presented as a potential projector to observe microscopic floating organisms or materials. In this experiment, a mosquito larva from a natural pond was selected as a demonstration sample. By shining a light beam from a laser pointer of any visible wavelength through the…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chemerisov, Sergey; Gromov, Roman; Makarashvili, Vakho
Argonne is assisting SHINE Medical Technologies in developing SHINE, a system for producing fission-product 99Mo using a D/T-accelerator to produce fission in a non-critical target solution of aqueous uranyl sulfate. We have developed an experimental setup for studying thermal-hydraulics and bubble formation in the uranyl sulfate solution to simulate conditions expected in the SHINE target solution during irradiation. A direct electron beam from the linac accelerator will be used to irradiate a 20 L solution (sector of the solution vessel). Because the solution will undergo radiolytic decomposition, we will be able to study bubble formation and dynamics and effects ofmore » convection and temperature on bubble behavior. These experiments will serve as a verification/ validation tool for the thermal-hydraulic model. Utilization of the direct electron beam for irradiation allows homogeneous heating of a large solution volume and simplifies observation of the bubble dynamics simultaneously with thermal-hydraulic data collection, which will complement data collected during operation of the miniSHINE experiment. Irradiation will be conducted using a 30-40 MeV electron beam from the high-power linac accelerator. The total electron-beam power will be 20 kW, which will yield a power density on the order of 1 kW/L. The solution volume will be cooled on the front and back surfaces and central tube to mimic the geometry of the proposed SHINE solution vessel. Also, multiple thermocouples will be inserted into the solution vessel to map thermal profiles. The experimental design is now complete, and installation and testing are in progress.« less
Targeted Killing, An Option for the Operational Commander
2007-11-06
punishment. In Peru , authorities had significant success derailing the brutal Shining Path terrorist group with the capture and display of a...demoralized Abimael Guzman in 1992. The once feared terrorist was described as an overweight pensioner when publicly displayed in prison garb by Peruvian...authorities.64 The Shining Path still exists but it has not recaptured its place as a real threat to Peru .65 Similarly, Turkey’s capture of Kurdish
Problem-Based Test: Functional Analysis of Mutant 16S rRNAs
ERIC Educational Resources Information Center
Szeberenyi, Jozsef
2010-01-01
Terms to be familiar with before you start to solve the test: ribosome, ribosomal subunits, antibiotics, point mutation, 16S, 5S, and 23S rRNA, Shine-Dalgarno sequence, mRNA, tRNA, palindrome, hairpin, restriction endonuclease, fMet-tRNA, peptidyl transferase, initiation, elongation, termination of translation, expression plasmid, transformation,…
Analyses of frameshifting at UUU-pyrimidine sites.
Schwartz, R; Curran, J F
1997-05-15
Others have recently shown that the UUU phenylalanine codon is highly frameshift-prone in the 3'(rightward) direction at pyrimidine 3'contexts. Here, several approaches are used to analyze frameshifting at such sites. The four permutations of the UUU/C (phenylalanine) and CGG/U (arginine) codon pairs were examined because they vary greatly in their expected frameshifting tendencies. Furthermore, these synonymous sites allow direct tests of the idea that codon usage can control frameshifting. Frameshifting was measured for these dicodons embedded within each of two broader contexts: the Escherichia coli prfB (RF2 gene) programmed frameshift site and a 'normal' message site. The principal difference between these contexts is that the programmed frameshift contains a purine-rich sequence upstream of the slippery site that can base pair with the 3'end of 16 S rRNA (the anti-Shine-Dalgarno) to enhance frameshifting. In both contexts frameshift frequencies are highest if the slippery tRNAPhe is capable of stable base pairing in the shifted reading frame. This requirement is less stringent in the RF2 context, as if the Shine-Dalgarno interaction can help stabilize a quasi-stable rephased tRNA:message complex. It was previously shown that frameshifting in RF2 occurs more frequently if the codon 3'to the slippery site is read by a rare tRNA. Consistent with that earlier work, in the RF2 context frameshifting occurs substantially more frequently if the arginine codon is CGG, which is read by a rare tRNA. In contrast, in the 'normal' context frameshifting is only slightly greater at CGG than at CGU. It is suggested that the Shine-Dalgarno-like interaction elevates frameshifting specifically during the pause prior to translation of the second codon, which makes frameshifting exquisitely sensitive to the rate of translation of that codon. In both contexts frameshifting increases in a mutant strain that fails to modify tRNA base A37, which is 3'of the anticodon. Thus, those base modifications may limit frameshifting at UUU codons. Finally, statistical analyses show that UUU Ynn dicodons are extremely rare in E.coli genes that have highly biased codon usage.
Analyses of frameshifting at UUU-pyrimidine sites.
Schwartz, R; Curran, J F
1997-01-01
Others have recently shown that the UUU phenylalanine codon is highly frameshift-prone in the 3'(rightward) direction at pyrimidine 3'contexts. Here, several approaches are used to analyze frameshifting at such sites. The four permutations of the UUU/C (phenylalanine) and CGG/U (arginine) codon pairs were examined because they vary greatly in their expected frameshifting tendencies. Furthermore, these synonymous sites allow direct tests of the idea that codon usage can control frameshifting. Frameshifting was measured for these dicodons embedded within each of two broader contexts: the Escherichia coli prfB (RF2 gene) programmed frameshift site and a 'normal' message site. The principal difference between these contexts is that the programmed frameshift contains a purine-rich sequence upstream of the slippery site that can base pair with the 3'end of 16 S rRNA (the anti-Shine-Dalgarno) to enhance frameshifting. In both contexts frameshift frequencies are highest if the slippery tRNAPhe is capable of stable base pairing in the shifted reading frame. This requirement is less stringent in the RF2 context, as if the Shine-Dalgarno interaction can help stabilize a quasi-stable rephased tRNA:message complex. It was previously shown that frameshifting in RF2 occurs more frequently if the codon 3'to the slippery site is read by a rare tRNA. Consistent with that earlier work, in the RF2 context frameshifting occurs substantially more frequently if the arginine codon is CGG, which is read by a rare tRNA. In contrast, in the 'normal' context frameshifting is only slightly greater at CGG than at CGU. It is suggested that the Shine-Dalgarno-like interaction elevates frameshifting specifically during the pause prior to translation of the second codon, which makes frameshifting exquisitely sensitive to the rate of translation of that codon. In both contexts frameshifting increases in a mutant strain that fails to modify tRNA base A37, which is 3'of the anticodon. Thus, those base modifications may limit frameshifting at UUU codons. Finally, statistical analyses show that UUU Ynn dicodons are extremely rare in E.coli genes that have highly biased codon usage. PMID:9115369
Takagi, Daisuke; Kondo, Naoki; Takada, Misato; Hashimoto, Hideki
2016-03-01
Evidence consistently shows that low education is associated with unhealthy behaviors. A recent study in behavioral economics argued that high time preferences - the tendency to prefer immediate gain to later reward - explain the limited self-control of individuals in making preventive health-related choices. The aim of this study was to examine the mediating effect of time preference on the associations between education and smoking, binge drinking and overweight in young and middle-aged adults living in a Japanese metropolitan area, using a quantitatively measured time discount rate. A population-based probabilistic sample of residents of 25-50 years of age living in four municipalities within Japanese metropolitan areas where economic disparity is relatively large was obtained from the Japanese Study on Stratification, Health, Income, and Neighborhood (J-SHINE). Respondents answered the questionnaire items using a computer-aided personal instrument (CAPI). Data from 3457 respondents were used in this study. Time preferences measured as categorical responses were converted into a continuous number of time discount rates by using the maximum likelihood method. Smoking habit, binge drinking, and body mass index were regressed on educational attainment with demographics and other confounders. The mediating effects of the time discount rate were examined with the bootstrapping method. Results showed that the time discount rate did not mediate the association between education and binge drinking and BMI. Even for smoking, the mediating effect of time discount rate was quite limited, indicating that the proportion of total effect of education mediated was only 4.3% for men and 3.0% for women. The results suggest that modifying time preferences through educational intervention has only limited efficacy in closing disparities in health-related behaviors, and that other mediators fostered by schooling, such as knowledge/skills, group norms and supportive peers/networks, may be more important as modifiable mediators in the link between education and smoking. Copyright © 2016 Elsevier Ltd. All rights reserved.
Beyond Guzman? The Future of the Shining Path in Peru
1992-12-01
order with. 4’ This relieves the stresses of everyday life, such as racism , sexism , poverty, and joblessness, because the Fourth Sword has given them...revolutionary phases are modeled on Mao’s three-phased theory of protracted revolutionary warfare." The Shining Path’s revolutionary ideology...in part from the collective-goods theory , and is similar in approach to Parsons’ four types of social control. See Talcott Parsons, "Reflections on
Puccetti, G; Thompson, W
2017-04-01
Hair sprays apply fixative ingredients to provide hold to a hair style as well as weather resistance and optical properties such as shine. Generally, sprays distribute fine particles containing polymeric ingredients to form a thin film on the surface of hair. Different hair types require different strengths of the formed deposit on the hair surface. The present study shows how sprays also alter the visibility of the hair colour by altering the surface topology of the hair fibres. Hyperspectral imaging is used to map spectral characteristics of hair on mannequins and panelists over the curvature of heads. Spectral and spatial characteristics are measured before and after hair spray applications. The hair surface is imaged by SEM to visualize the degree of cuticle coverage. Finally, the perception of hair colour was evaluated on red-coloured mannequins by consumer questionnaire. Hair sprays deposit different degrees of fixatives, which lead to a progressive leveling of the cuticle natural tilt angle with respect to the fibre axis. As a result, shine is progressively shifting towards the region of hair colour visibility and decreases the perceived colour of hair seen by consumers. Lighter sprays show thinner film formation on the hair surface and less of a shine shift than strong hold hair sprays. Hair sprays are generally employed for hair style hold and weather resistance and considered without effect on hair colour. Our approach shows that spray-deposited films can affect colour perception by altering the microstructure of the hair surface. Thin films deposited on the hair fibre surface can partially fill gaps between cuticles, which reduces the cuticle natural angle. This partial erasure results in a angle shift of the shine regions towards the angle of internal reflection, thus decreasing the perceived hair colour regions as experienced by a group of consumers. © 2016 Society of Cosmetic Scientists and the Société Française de Cosmétologie.
[Fire worship on Soratte: form prehistory to present days].
Falchetti, Mario; Ottini, Laura
2013-01-01
Fire has always been involved in human thoughts, believes and actions. For many psychological reasons fire has been considered as living power: red as the human blood, warm as the human body, clearly shines in the night. Fire worship is very common, especially in regions where terrestrial fire is believed to be the image of the heavenly fire. Fire worship has represented the base for symbolic systems involved in the cultural-anthropological evolution of populations settled close to mount Soratte. Fire cults in this region have originated in independent and long-time separated contexts, according to available knowledge. Hirpi Sorani, ancient inhabitants of mount Soratte territory, celebrated Sorano Apollo by a famous fire walking ceremony, with a likely cathartic and apotropaic meaning, as reported by ancient Roman writers. The victory of Christianity over paganism caused the decline of these religious practices. The beginning of the XIX century witnessed the establishment ofa new kind of devotion to the Virgin Mary at the mount Soratte. Today, this religious piety-linked identity has weakened due to changes in lifestyles,from an agricultural to one based on outside home employment, and has been largely shifted on cultural and anthropological bases. In conclusion, fire worship at mount Soratte has evolved because of external influences and local inhabitants have reacted by asserting their own identity.
St George, Sara M; Wilson, Dawn K; McDaniel, Tyler; Alia, Kassandra A
2016-07-01
This study describes the process evaluation of Project SHINE, a randomized family-based health promotion intervention that integrated parenting and peer monitoring for improving sedentary behavior, physical activity, and diet in African American families. Adolescent-parent dyads (n = 89) were randomized to a 6-week behavioral, positive parenting, and peer monitoring skills intervention or a general health education comparison condition. Process evaluation included observational ratings of fidelity, attendance records, psychosocial measures, and qualitative interviews. Results indicated that the intervention was delivered with high fidelity based on facilitator adherence (>98% of content delivered) and competent use of theoretically based behavior change and positive parenting skills (100% of ratings >3 on a 1-4 scale). Although only 43% of peers attended the "bring a friend" session, overall attendance was high (4.39 ± 1.51 sessions) as was the retention rate (88%). Parents in the intervention condition reported significant improvements in communication related to adolescents' engagement in health behaviors both on their own and with peers. These findings were supported by qualitative themes related to improvements in family communication and connectedness. This study provides an innovative example of how future family-based health promotion trials can expand their process evaluation approaches by assessing theoretically relevant positive parenting variables as part of ongoing monitoring. © 2016 Society for Public Health Education.
NASA Astrophysics Data System (ADS)
Merzlaya, Anastasia;
2017-01-01
The heavy-ion programme of the NA61/SHINE experiment at CERN SPS is expanding to allow precise measurements of exotic particles with lifetime few hundred microns. A Vertex Detector for open charm measurements at the SPS is being constructed by the NA61/SHINE Collaboration to meet the challenges of high spatial resolution of secondary vertices and efficiency of track registration. This task is solved by the application of the coordinate sensitive CMOS Monolithic Active Pixel Sensors with extremely low material budget in the new Vertex Detector. A small-acceptance version of the Vertex Detector is being tested this year, later it will be expanded to a large-acceptance version. Simulation studies will be presented. A method of track reconstruction in the inhomogeneous magnetic field for the Vertex Detector was developed and implemented. Numerical calculations show the possibility of high precision measurements in heavy ion collisions of strange and multi strange particles, as well as heavy flavours, like charmed particles.
Recent NA61/SHINE measurements performed for the T2K experiment
NASA Astrophysics Data System (ADS)
2017-12-01
The neutrino programme of the NA61/ SHINE experiment at the CERN SPS is aiming to deliver precise hadron production measurements for improving calculations of the initial neutrino beam flux in the long-baseline neutrino oscillation experiments. The first receiver of such measurements is the T2K neutrino oscillation project in Japan. New results on π±, K±, p, K0S and Λ production from the NA61/SHINE 2009 thin target data analyses with smaller statistical and systematic errors are discussed. They enable us to reduce further the flux uncertainties in T2K for neutrino and antineutrino beam mode. We also report on the first corrected π± results obtained for T2K replica target (a 90 cm long cylinder of 2.6 cm diameter, about 1.9λI). Up to 90% of the neutrino flux can be constrained by such measurements as compared to 60% for the thin target measurements that are sensitive only to primary hadron interactions.
2017-05-01
supports a Europe that is “whole and free ,” and one that is based on Western institutions and democratic principles. 15. SUBJECT TERMS Serbia...a Europe that is “whole and free ,” and one that is based on Western institutions and democratic principles. ii This page...security. Strategic reengagement from the U.S. and its European partners will be critical in order to ensure that Europe remains “whole and free
2010-12-01
enjoying such success. The Shining Path of Peru started its armed struggle modeled along the Maoist doctrine in May 1980. The insurgency quickly...Maria Sison and based almost entirely on Mao’s doctrine of peasant-based mass revolution.4 The movement gathered strength with the election of...Conflicts (Philadelphia: University of Pennsylvania Press, 2007), 2. 6 classic Maoist “people’s war” doctrine , its leaders were ready to accept political
Takada, Misato; Kondo, Naoki; Hashimoto, Hideki
2014-01-01
Background The Japanese Study on Stratification, Health, Income, and Neighborhood (J-SHINE) aims to clarify the complex associations between social factors and health from an interdisciplinary perspective and to provide a database for use in various health policy evaluations. Methods J-SHINE is an ongoing longitudinal panel study of households of adults aged 25–50 years. The wave 1 survey was carried out in 2010 among adults randomly selected from the resident registry of four urban and suburban municipalities in the greater Tokyo metropolitan area, Japan. In 2011, surveys for the participants’ spouse/partner and child were additionally conducted. The wave 2 survey was conducted in 2012 for the wave 1 participants and will be followed by the wave 2 survey for spouse/partner and child in 2013. Results Wave 1 sample sizes were 4357 for wave 1 participants (valid response rate: 31.3%; cooperation rate: 51.8%), 1873 for spouse/partner (response rate: 61.9%), and 1520 for child (response rate: 67.7%). Wave 2 captured 69.0% of wave 1 participants. Information gathered covered socio-demographics, household economy, self-reported health conditions and healthcare utilization, stress and psychological values, and developmental history. A subpopulation underwent physiological (n = 2468) and biomarker (n = 1205) measurements. Conclusions Longitudinal survey data, including repeated measures of social factors evaluated based on theories and techniques of various disciplines, like J-SHINE, should contribute toward opening a web of causality for society and health, which may have important policy implications for recent global health promotion strategies such as the World Health Organization’s Social Determinants of Health approach and the second round of Japan’s Healthy Japan 21. PMID:24814507
Takada, Misato; Kondo, Naoki; Hashimoto, Hideki
2014-01-01
The Japanese Study on Stratification, Health, Income, and Neighborhood (J-SHINE) aims to clarify the complex associations between social factors and health from an interdisciplinary perspective and to provide a database for use in various health policy evaluations. J-SHINE is an ongoing longitudinal panel study of households of adults aged 25-50 years. The wave 1 survey was carried out in 2010 among adults randomly selected from the resident registry of four urban and suburban municipalities in the greater Tokyo metropolitan area, Japan. In 2011, surveys for the participants' spouse/partner and child were additionally conducted. The wave 2 survey was conducted in 2012 for the wave 1 participants and will be followed by the wave 2 survey for spouse/partner and child in 2013. Wave 1 sample sizes were 4357 for wave 1 participants (valid response rate: 31.3%; cooperation rate: 51.8%), 1873 for spouse/partner (response rate: 61.9%), and 1520 for child (response rate: 67.7%). Wave 2 captured 69.0% of wave 1 participants. Information gathered covered socio-demographics, household economy, self-reported health conditions and healthcare utilization, stress and psychological values, and developmental history. A subpopulation underwent physiological (n = 2468) and biomarker (n = 1205) measurements. Longitudinal survey data, including repeated measures of social factors evaluated based on theories and techniques of various disciplines, like J-SHINE, should contribute toward opening a web of causality for society and health, which may have important policy implications for recent global health promotion strategies such as the World Health Organization's Social Determinants of Health approach and the second round of Japan's Healthy Japan 21.
Lu, Changrui; Smith, Angela M; Fuchs, Ryan T; Ding, Fang; Rajashankar, Kanagalaghatta; Henkin, Tina M; Ke, Ailong
2011-01-01
Three distinct classes of S-adenosyl-l-methionine (SAM)-responsive riboswitches have been identified that regulate bacterial gene expression at the levels of transcription attenuation or translation inhibition. The SMK box (SAM-III) translational riboswitch has been identified in the SAM synthetase gene in members of the Lactobacillales. Here we report the 2.2-Å crystal structure of the Enterococcus faecalis SMK box riboswitch. The Y-shaped riboswitch organizes its conserved nucleotides around a three-way junction for SAM recognition. The Shine-Dalgarno sequence, which is sequestered by base-pairing with the anti–Shine-Dalgarno sequence in response to SAM binding, also directly participates in SAM recognition. The riboswitch makes extensive interactions with the adenosine and sulfonium moieties of SAM but does not appear to recognize the tail of the methionine moiety. We captured a structural snapshot of the SMK box riboswitch sampling the near-cognate ligand S-adenosyl-l-homocysteine (SAH) in which SAH was found to adopt an alternative conformation and fails to make several key interactions. PMID:18806797
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lu, C.; Smith, A.M.; Fuchs, R.T.
2010-01-07
Three distinct classes of S-adenosyl-L-methionine (SAM)-responsive riboswitches have been identified that regulate bacterial gene expression at the levels of transcription attenuation or translation inhibition. The SMK box (SAM-III) translational riboswitch has been identified in the SAM synthetase gene in members of the Lactobacillales. Here we report the 2.2-{angstrom} crystal structure of the Enterococcus faecalis SMK box riboswitch. The Y-shaped riboswitch organizes its conserved nucleotides around a three-way junction for SAM recognition. The Shine-Dalgarno sequence, which is sequestered by base-pairing with the anti-Shine-Dalgarno sequence in response to SAM binding, also directly participates in SAM recognition. The riboswitch makes extensive interactions withmore » the adenosine and sulfonium moieties of SAM but does not appear to recognize the tail of the methionine moiety. We captured a structural snapshot of the SMK box riboswitch sampling the near-cognate ligand S-adenosyl-L-homocysteine (SAH) in which SAH was found to adopt an alternative conformation and fails to make several key interactions.« less
Orbiting Carbon Observatory-2 (OCO-2) Launch
2014-07-02
Lights shine on the umbilical tower shortly after a United Launch Alliance Delta II rocket launched with the Orbiting Carbon Observatory-2 (OCO-2)satellite onboard from Space Launch Complex 2 at Vandenberg Air Force Base, Calif. on Wednesday, July 2, 2014. OCO-2 will measure the global distribution of carbon dioxide, the leading human-produced greenhouse gas driving changes in Earth’s climate. Photo Credit: (NASA/Bill Ingalls)
NASA Astrophysics Data System (ADS)
Venkatesan, R.; Mathiyarasu, R.; Somayaji, K. M.
Ground level concentration and sky-shine dose due to radioactive emissions from a nuclear power plant at a coastal site have been estimated using the standard Gaussian Plume Model (GPM) and the modified GPM suggested by Misra (Atmospheric Environment 14 (1980) 397), which incorporates fumigation effect under sea breeze condition. The difference in results between these two models is analysed in order to understand their significance and errors that would occur if proper choice were not made. Radioactive sky-shine dose from 41Ar, emitted from a 100 m stack of the nuclear plant is continuously recorded by environmental gamma dose monitors and the data is used to validate the modified GPM. It is observed that the dose values increase by a factor of about 2 times than those of the standard GPM estimates, up to a downwind distance of 6 km during sea breeze hours. In order to examine the dispersion of radioactive effluents in the mesoscale range, a sea breeze model coupled with a particle dispersion model is used. The deposited activity, thyroid dose and sky-shine radioactive dose are simulated for a range of 30 km. In this range, the plume is found to deviate from its straight-line trajectory, as otherwise assumed in GPM. A secondary maximum in the concentration and the sky-shine dose is also observed in the model results. These results are quite significant in realistically estimating the area affected under any unlikely event of an accidental release of radioactivity.
Cognitive disorganisation in schizotypy is associated with deterioration in visual backward masking.
Cappe, Céline; Herzog, Michael H; Herzig, Daniela A; Brand, Andreas; Mohr, Christine
2012-12-30
To understand the causes of schizophrenia, a search for stable markers (endophenotypes) is ongoing. In previous years, we have shown that the shine-through visual backward masking paradigm meets the most important characteristics of an endophenotype. Here, we tested masking performance differences between healthy students with low and high schizotypy scores as determined by the self-report O-Life questionnaire assessing schizotypy along three dimensions, i.e. positive schizotypy (unusual experiences), cognitive disorganisation, and negative schizotypy (introvertive anhedonia). Forty participants performed the shine-through backward masking task and a classical cognitive test, the Wisconsin Card Sorting Task (WCST). We found that visual backward masking was impaired for students scoring high as compared to low on the cognitive disorganisation dimension, whereas the positive and negative schizotypy dimensions showed no link to masking performance. We also found group differences for students scoring high and low on the cognitive disorganisation factor for the WCST. These findings indicate that the shine-through paradigm is sensitive to differences in schizotypy which are closely linked with the pathological expression in schizophrenia. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Compendium of Phase-I Mini-SHINE Experiments
DOE Office of Scientific and Technical Information (OSTI.GOV)
Youker, Amanda J.; Chemerisov, Sergey D.; Tkac, Peter
Argonne National Laboratory is assisting SHINE Medical Technologies in their efforts to develop the technology to become a domestic Mo-99 producer using low-enriched uranium (LEU). Mini-SHINE experiments are being performed with the high-current electron linear accelerator (linac) at Argonne. The target solution is a 90-150 g-U/L LEU uranyl sulfate at pH 1. In Phase 1, the convertor was tantalum with a maximum beam power on the convertor of 10 kW, and the target solution was limited to 5 L. This configuration generated a peak fission power density of 0.05 W/mL. Nine experiments were performed between February and October 2015. Resultsmore » are reported and discussed for each experiment regarding the off-gas analysis system, the sampling and Mo-recovery operation, and the Mo-product concentration and purification system. In Phase 2, the convertor will be depleted uranium; beam power will increase to 20 kW; and the solution volume will be 18 L. This configuration will generate a fission power density of up to 1 W/mL.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pawel, Steven J.
2014-10-01
Laboratory corrosion testing of candidate alloys—including Zr-4 and Zr-2.5Nb representing the target solution vessel, and 316L, 2304, 304L, and 17-4 PH stainless steels representing process piping and balance-of-plant components—was performed in support of the proposed SHINE process to produce 99Mo from low-enriched uranium. The test solutions used depleted uranyl sulfate in various concentrations and incorporated a range of temperatures, excess sulfuric acid concentrations, nitric acid additions (to simulate radiolysis product generation), and iodine additions. Testing involved static immersion of coupons in solution and in the vapor above the solution, and was extended to include planned-interval tests to examine details associatedmore » with stainless steel corrosion in environments containing iodine species. A large number of galvanic tests featuring couples between a stainless steel and a zirconium-based alloy were performed, and limited vibratory horn testing was incorporated to explore potential erosion/corrosion features of compatibility. In all cases, corrosion of the zirconium alloys was observed to be minimal, with corrosion rates based on weight loss calculated to be less than 0.1 mil/year with no change in surface roughness. The resulting passive film appeared to be ZrO2 with variations in thickness that influence apparent coloration (toward light brown for thicker films). Galvanic coupling with various stainless steels in selected exposures had no discernable effect on appearance, surface roughness, or corrosion rate. Erosion/corrosion behavior was the same for zirconium alloys in uranyl sulfate solutions and in sodium sulfate solutions adjusted to a similar pH, suggesting there was no negative effect of uranium resulting from fluid dynamic conditions aggressive to the passive film. Corrosion of the candidate stainless steels was similarly modest across the entire range of exposures. However, some sensitivity to corrosion of the stainless steels was observed in solutions with 50 wppm iodine (the actual SHINE process expects 0.1–1 wppm) with the highest corrosion rates (up to ~6 mil/year) observed on specimens exposed in the vapor phase. Lower concentrations of iodine species (5 or 28 wppm) proved much less corrosive, and the planned-interval data indicated that metal corrodibility decreased with time for all immersed exposures and, with one minor exception, all vapor exposures. Little change in susceptibility to corrosion was observed as a result of nitric acid additions to the test environment (simulating radiolysis products). The trend toward reduced corrosion (immersion and vapor phase) with decreasing iodine concentration suggests that, at the expected conditions in the SHINE process, it is unlikely that iodine species will generate a general corrosion concern for the candidate stainless steels.« less
The Allure of Quick Victory. Lessons from Peru’s Fight Against Sendero Luminoso
2010-10-01
example of successful government consolidation following an internal conflict. 1. “Si no hacemos algo tendremos unas FARC,” El Comercio (19 April 2009...and Shining Path in Peru,” Shining Path of Peru, 3-4. 18. “Suman 15 los Soldados Asesinados,” El Comercio , 22 April 2009. 19. “Por lo menos 50...terroristas atacaron sede policial del poblado de San Jose de Secce,” El Comercio , 2 August 2009. 20. “Helicóptero Caído Cumplía Misión de Rescate de Heridos
On psychoanalytic supervision as signature pedagogy.
Watkins, C Edward
2014-04-01
What is signature pedagogy in psychoanalytic education? This paper examines that question, considering why psychoanalytic supervision best deserves that designation. In focusing on supervision as signature pedagogy, I accentuate its role in building psychoanalytic habits of mind, habits of hand, and habits of heart, and transforming theory and self-knowledge into practical product. Other facets of supervision as signature pedagogy addressed in this paper include its features of engagement, uncertainty, formation, and pervasiveness, as well as levels of surface, deep, and implicit structure. Epistemological, ontological, and axiological in nature, psychoanalytic supervision engages trainees in learning to do, think, and value what psychoanalytic practitioners in the field do, think, and value: It is, most fundamentally, professional preparation for competent, "good work." In this paper, effort is made to shine a light on and celebrate the pivotal role of supervision in "making" or developing budding psychoanalysts and psychoanalytic psychotherapists. Now over a century old, psychoanalytic supervision remains unparalleled in (1) connecting and integrating conceptualization and practice, (2) transforming psychoanalytic theory and self-knowledge into an informed analyzing instrument, and (3) teaching, transmitting, and perpetuating the traditions, practice, and culture of psychoanalytic treatment.
Koizumi, Amane; Nagata, Osamu; Togawa, Morio; Sazi, Toshiyuki
2014-01-01
Neuroscience is an expanding field of science to investigate enigmas of brain and human body function. However, the majority of the public have never had the chance to learn the basics of neuroscience and new knowledge from advanced neuroscience research through hands-on experience. Here, we report that we produced the Muscle Sensor, a simplified electromyography, to promote educational understanding in neuroscience. The Muscle Sensor can detect myoelectric potentials which are filtered and processed as 3-V pulse signals to shine a light bulb and emit beep sounds. With this educational tool, we delivered "On-Site Neuroscience Lectures" in Japanese junior-high schools to facilitate hands-on experience of neuroscientific electrophysiology and to connect their text-book knowledge to advanced neuroscience researches. On-site neuroscience lectures with the Muscle Sensor pave the way for a better understanding of the basics of neuroscience and the latest topics such as how brain-machine-interface technology could help patients with disabilities such as spinal cord injuries. Copyright © 2013 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.
Discourse on pulse in medieval Persia--the Hidayat of Al-Akhawayni (?-983 A D.).
Khodadoust, Kazem; Ardalan, Mohammadreza; Ghabili, Kamyar; Golzari, Samad E J; Eknoyan, Garabed
2013-06-20
In a period of compilation, original observations and expansion (900-1100 A.D.), Persians described new clinical manifestations of the diseases and expanded the earlier knowledge of materia medica. In the epoch of the Arabic language domination in the scientific literature of this period, advent of medical authors to write in Farsi shined in the Persian principalities. Akhawayani Bokhari was by far the most outstanding scholar of the time who wrote one of the earliest pandects of medicine of the period, the Hidayat al-Mutallimin fi al-Tibb (Learner's Guide to Medicine) in new Persian. The Hidayat is a relatively short and simplified digest of medicine at the time providing a glimpse of high level of medical education at the Samanid period (819-999). The present article is a translation of the sections of the Hidayat related to the pulse and its characters and conditions affecting the pulse in an attempt to increase our knowledge of the medicine, and particularly the pulse examination throughout the medieval era. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Design of a detection system of highlight LED arrays' effect on the human organization
NASA Astrophysics Data System (ADS)
Chen, Shuwang; Shi, Guiju; Xue, Tongze; Liu, Yanming
2009-05-01
LED (Light Emitting Diode) has many advantages in the intensity, wavelength, practicality and price, so it is feasible to apply in biomedicine engineering. A system for the research on the effect of highlight LED arrays to human organization is designed. The temperature of skin surface can rise if skin and organization are in irradiation by highlight LED arrays. The metabolism and blood circulation of corresponding position will be quicker than those not in the shine, so the surface temperature will vary in different position of skin. The structure of LED source arrays system is presented and a measure system for studying LED's influence on human organization is designed. The temperature values of shining point are detected by infrared temperature detector. Temperature change is different according to LED parameters, such as the number, irradiation time and luminous intensity of LED. Experimental device is designed as an LED arrays pen. The LED arrays device is used to shine the points of human body, then it may effect on personal organization as well as the acupuncture. The system is applied in curing a certain skin disease, such as age pigment, skin cancer and fleck.
Luster measurements of lips treated with lipstick formulations.
Yadav, Santosh; Issa, Nevine; Streuli, David; McMullen, Roger; Fares, Hani
2011-01-01
In this study, digital photography in combination with image analysis was used to measure the luster of several lipstick formulations containing varying amounts and types of polymers. A weighed amount of lipstick was applied to a mannequin's lips and the mannequin was illuminated by a uniform beam of a white light source. Digital images of the mannequin were captured with a high-resolution camera and the images were analyzed using image analysis software. Luster analysis was performed using Stamm (L(Stamm)) and Reich-Robbins (L(R-R)) luster parameters. Statistical analysis was performed on each luster parameter (L(Stamm) and L(R-R)), peak height, and peak width. Peak heights for lipstick formulation containing 11% and 5% VP/eicosene copolymer were statistically different from those of the control. The L(Stamm) and L(R-R) parameters for the treatment containing 11% VP/eicosene copolymer were statistically different from these of the control. Based on the results obtained in this study, we are able to determine whether a polymer is a good pigment dispersant and contributes to visually detected shine of a lipstick upon application. The methodology presented in this paper could serve as a tool for investigators to screen their ingredients for shine in lipstick formulations.
What Hansel and Gretel’s Trail Teach Us about Knowledge Management
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wayne Simpson; Troy Hiltbrand
Background At Idaho National Laboratory (INL), we are on the cusp of a significant era of change. INL is the lead Department of Energy Nuclear Research and Development Laboratory, focused on finding innovative solutions to the nation’s energy challenges. Not only has the Laboratory grown at an unprecedented rate over the last five years, but also has a significant segment of its workforce that is ready for retirement. Over the next 10 years, it is anticipated that upwards of 60% of the current workforce at INL will be eligible for retirement. Since the Laboratory is highly dependent on the intellectualmore » capabilities of its scientists and engineers and their efforts to ensure the future of the nation’s energy portfolio, this attrition of resources has the potential of seriously impacting the ability of the Laboratory to sustain itself and the growth that it has achieved in the past years. Similar to Germany in the early nineteenth century, we face the challenge of our self-identity and must find a way to solidify our legacy to propel us into the future. Approach As the Brothers Grimm set out to collect their fairy tales, they focused on gathering information from the people that were most knowledgeable in the subject. For them, it was the peasants, with their rich knowledge of the region’s sub-culture of folk lore that was passed down from generation to generation around the evening fire. As we look to capture this tacit knowledge, it is requisite that we also seek this information from those individuals that are most versed in it. In our case, it is the scientists and researchers who have dedicated their lives to providing the nation with nuclear energy. This information comes in many forms, both digital and non-digital. Some of this information still resides in the minds of these scientists and researchers who are close to retirement, or who have already retired. Once the information has been collected, it has to be sorted through to identify where the “shining stones” can be found. The quantity of this information makes it improbable for an individual or set of individuals to sort through it and pick out those ideas which are most important. To accomplish both the step of information capture and classification, modern advancements in technology give us the tools that we need to successfully capture this tacit knowledge. To assist in this process, we have evaluated multiple tools and methods that will help us to unlock the power of tacit knowledge. Tools The first challenge that stands in the way of success is the capture of information. More than 50 years of nuclear research is captured in log books, microfiche, and other non-digital formats. To transform this information from its current form into a format that can “shine,” requires a number of different tools. These tools fall into three major categories: Information Capture, Content Retrieval, and Information Classification. Information Capture The first step is to capture the information from a myriad of sources. With knowledge existing in multiple formats, this step requires multiple approaches to be successful. Some of the sources that require consideration include handwritten documents, typed documents, microfiche, images, audio and video feeds, and electronic images. To make this step feasible for a large body of knowledge requires automation.« less
John Bahcall and the Solar Neutrino Problem
NASA Astrophysics Data System (ADS)
Bahcall, Neta
2016-03-01
``I feel like dancing'', cheered John Bahcall upon hearing the exciting news from the SNO experiment in 2001. The results confirmed, with remarkable accuracy, John's 40-year effort to predict the rate of neutrinos from the Sun based on sophisticated Solar models. What began in 1962 by John Bahcall and Ray Davis as a pioneering project to test and confirm how the Sun shines, quickly turned into a four-decade-long mystery of the `Solar Neutrino Problem': John's models predicted a higher rate of neutrinos than detected by Davis and follow-up experiments. Was the theory of the Sun wrong? Were John's calculations in error? Were the neutrino experiments wrong? John worked tirelessly to understand the physics behind the Solar Neutrino Problem; he led the efforts to greatly increase the accurately of the solar model, to understand its seismology and neutrino fluxes, to use the neutrino fluxes as a test for new physics, and to advocate for important new experiments. It slowly became clear that none of the then discussed possibilities --- error in the Solar model or neutrino experiments --- was the culprit. The SNO results revealed that John's calculations, and hence the theory of the Solar model, have been correct all along. Comparison of the data with John's theory demanded new physics --- neutrino oscillations. The Solar Neutrino saga is one of the most amazing scientific stories of the century: exploring a simple question of `How the Sun Shines?' led to the discovery of new physics. John's theoretical calculations are an integral part of this journey; they provide the foundation for the Solar Neutrino Problem, for confirming how the Sun shines, and for the need of neutrino oscillations. His tenacious persistence, dedication, enthusiasm and love for the project, and his leadership and advocacy of neutrino physics over many decades are a remarkable story of scientific triumph. I know John is smiling today.
Thin-film thickness measurement method based on the reflection interference spectrum
NASA Astrophysics Data System (ADS)
Jiang, Li Na; Feng, Gao; Shu, Zhang
2012-09-01
A method is introduced to measure the thin-film thickness, refractive index and other optical constants. When a beam of white light shines on the surface of the sample film, the reflected lights of the upper and the lower surface of the thin-film will interfere with each other and reflectivity of the film will fluctuate with light wavelength. The reflection interference spectrum is analyzed with software according to the database, while the thickness and refractive index of the thin-film is measured.
SHINE, The SpHere INfrared survey for Exoplanets
NASA Astrophysics Data System (ADS)
Chauvin, G.; Desidera, S.; Lagrange, A.-M.; Vigan, A.; Feldt, M.; Gratton, R.; Langlois, M.; Cheetham, A.; Bonnefoy, M.; Meyer, M.
2017-12-01
The SHINE survey for SPHERE High-contrast ImagiNg survey for Exoplanets, is a large near-infrared survey of 400-600 young, nearby stars and represents a significant component of the SPHERE consortium Guaranteed Time Observations consisting in 200 observing nights. The scientific goals are: i) to characterize known planetary systems (architecture, orbit, stability, luminosity, atmosphere); ii) to search for new planetary systems using SPHERE's unprecedented performance; and finally iii) to determine the occurrence and orbital and mass function properties of the wide-orbit, giant planet population as a function of the stellar host mass and age. Combined, the results will increase our understanding of planetary atmospheric physics and the processes of planetary formation and evolution.
SHINE Tritium Nozzle Design: Activity 6, Task 1 Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Okhuysen, Brett S.; Pulliam, Elias Noel
In FY14, we studied the qualitative and quantitative behavior of a SHINE/PNL tritium nozzle under varying operating conditions. The result is an understanding of the nozzle’s performance in terms of important flow features that manifest themselves under different parametric profiles. In FY15, we will consider nozzle design with a focus on nozzle geometry and integration. From FY14 work, we will understand how the SHINE/PNL nozzle behaves under different operating scenarios. The first task for FY15 is to evaluate the FY14 model as a predictor of the actual flow. Considering different geometries is more time-intensive than parameter studies, therefore we recommendmore » considering any relevant flow features that were not included in the FY14 model. In the absence of experimental data, it is particularly important to consider any sources of heat in the domain or boundary conditions that may affect the flow and incorporate these into the simulation if they are significant. Additionally, any geometric features of the beamline segment should be added to the model such as the orifice plate. The FY14 model works with hydrogen. An improvement that can be made for FY15 is to develop CFD properties for tritium and incorporate those properties into the new models.« less
2017-12-08
Twice a year, NASA’s Solar Dynamics Observatory, or SDO, has an eclipse season — a weeks-long period in which Earth blocks SDO’s view of the sun for part of each day. This footage captured by SDO on Feb. 15, 2017, shows one such eclipse. Earth’s edge appears fuzzy, rather than crisp, because the sun’s light is able to shine through Earth’s atmosphere in some places. These images were captured in wavelengths of extreme ultraviolet light, which is typically invisible to our eyes, but is colorized here in gold. Credit: NASA/Goddard/SDO NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bennett, Megan E.; Bowers, Delbert L.; Vandegrift, George F.
2015-09-01
During FY 2012 and 2013, a process was developed to convert the SHINE Target Solution (STS) of irradiated uranyl sulfate (140 g U/L) to uranyl nitrate. This process is necessary so that the uranium solution can be processed by the UREX (Uranium Extraction) separation process, which will remove impurities from the uranium so that it can be recycled. The uranyl sulfate solution must contain <0.02 M SO 4 2- so that the uranium will be extractable into the UREXsolvent. In addition, it is desired that the barium content be below 0.0007 M, as this is the limit in the Resourcemore » Conservation and Recovery Act (RCRA).« less
Whatever Shines Should be Observed
NASA Astrophysics Data System (ADS)
McKenna-Lawlor, S. M. P.
2003-08-01
It is good to mark the new Millennium by looking back as well as forward. Whatever Shines should be Observed looks to the nineteenth century to celebrate the achievements of five distinguished women, four of whom were born in Ireland while the fifth married into an Irish family, who made pioneering contributions to photography, microscopy, astronomy and astrophysics. The women featured came from either aristocratic or professional families. Thus, at first sight, they had many material advantages among their peers. In the ranks of the aristocracy there was often a great passion for learning, and the mansions in which these families lived contained libraries, technical equipment (microscopes and telescopes) and collections from the world of nature. More modest professional households of the time were rich in books, while activities such as observing the stars, collecting plants etc. typically formed an integral part of the children's education. To balance this it was the prevailing philosophy that boys could learn, in addition to basic subjects, mathematics, mechanics, physics, chemistry and classical languages, while girls were channelled into 'polite' subjects like music and needlework. This arrangement allowed boys to progress to University should they so wish, where a range of interesting career choices (including science and engineering) was open to them. Girls, on the other hand, usually received their education at home, often under the tutelage of a governess who would not herself had had any serious contact with scientific or technical subjects. In particular, progress to University was not during most of the nineteenth century an option for women, and access to scientific libraries and institutions was also prohibited. Although those women with aristocratic and professional backgrounds were in a materially privileged position and had an opportunity to 'see' through the activities of their male friends and relatives how professional scientific life was lived, to progress from their places in society to the professions required very special determination. Firstly, they had to individually acquire scientific and technical knowledge, as well as necessary laboratory methodology, without the advantage of formal training. Then, it was necessary to carve out a niche in a particular field, despite the special difficulties attending the publication of scientific books or articles by a woman. There was no easy road to science, or even any well worn track. To achieve recognition was a pioneering activity without discernible ground rules. With the hindsight of history, we recognise that the heroic efforts which the women featured in this volume made to overcome the social constraints that held them back from learning about, and participating in, scientific and technical subjects, had a consequence on a much broader canvas. In addition to what they each achieved professionally, they contributed within society to a gradual erosion of those barriers raised against the participation of women in academic life, thereby assisting in allowing University places and professional opportunities to gradually become generally available. It is a privilege to salute and thank the wonderful women of the nineteenth century herein described for what they have contributed to the women of today. William Herschel's famous motto quicquid nitet notandum (whatever shines should be observed) applies in a particular way to the luminous quality of their individual lives, and those of us who presently observe their shining, as well as those who now wait in the wings of the coming centuries to emerge upon the scene, may each see a little further by their light. Link: http://www.wkap.nl/prod/b/1-4020-1424-4
Uranium Detection - Technique Validation Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Colletti, Lisa Michelle; Garduno, Katherine; Lujan, Elmer J.
As a LANL activity for DOE/NNSA in support of SHINE Medical Technologies™ ‘Accelerator Technology’ we have been investigating the application of UV-vis spectroscopy for uranium analysis in solution. While the technique has been developed specifically for sulfate solutions, the proposed SHINE target solutions, it can be adapted to a range of different solution matrixes. The FY15 work scope incorporated technical development that would improve accuracy, specificity, linearity & range, precision & ruggedness, and comparative analysis. Significant progress was achieved throughout FY 15 addressing these technical challenges, as is summarized in this report. In addition, comparative analysis of unknown samples usingmore » the Davies-Gray titration technique highlighted the importance of controlling temperature during analysis (impacting both technique accuracy and linearity/range). To fully understand the impact of temperature, additional experimentation and data analyses were performed during FY16. The results from this FY15/FY16 work were presented in a detailed presentation, LA-UR-16-21310, and an update of this presentation is included with this short report summarizing the key findings. The technique is based on analysis of the most intense U(VI) absorbance band in the visible region of the uranium spectra in 1 M H 2SO 4, at λ max = 419.5 nm.« less
'She sort of shines': midwives' accounts of 'good' midwifery and 'good' leadership.
Byrom, Sheena; Downe, Soo
2010-02-01
to explore midwives' accounts of the characteristics of 'good' leadership and 'good' midwifery. a phenomenological interview survey. Participants were asked about what made both good and poor midwives and leaders. two maternity departments within National Health Service trusts in the North West of England. qualified midwives, selected by random sampling stratified to encompass senior and junior grades. thematic analysis, carried out manually. ten midwives were interviewed. Sixteen codes and six sub-themes were generated. Across the responses, two clear dimensions (themes) were identified, relating on the one hand to aspects of knowledge, skill and competence (termed 'skilled competence'), and on the other hand to specific personality characteristics (termed 'emotional intelligence'). This study suggests that the ability to act knowledgeably, safely and competently was seen as a basic requirement for both clinical midwives and midwife leaders. The added element which made both the midwife and the leader 'good' was the extent of their emotional capability. this small-scale in-depth study could form the basis for hypothesis generation for larger scale work in this area in future. The findings offer some reinforcement for the potential applicability of theories of transformational leadership to midwifery management and practice. Copyright 2008 Elsevier Ltd. All rights reserved.
Stefan, Alessandra; Schwarz, Flavio; Bressanin, Daniela; Hochkoeppler, Alejandro
2010-11-01
Silencing of the lacZ gene in Escherichia coli was attempted by means of the expression of antisense RNAs (asRNAs) in vivo. A short fragment of lacZ was cloned into the pBAD expression vector, in reverse orientation, using the EcoRI and PstI restriction sites. This construct (pBAD-Zcal1) was used to transform E. coli cells, and the antisense transcription was induced simply by adding arabinose to the culture medium. We demonstrated that the Zcal1 asRNA effectively silenced lacZ using β-galactosidase activity determinations, SDS-PAGE, and Western blotting. Because the concentration of the lac mRNA was always high in cells that expressed Zcal1, we hypothesize that this antisense acts by inhibiting messenger translation. Similar analyses, performed with a series of site-specific Zcal1 mutants, showed that the Shine-Dalgarno sequence, which is conferred by the pBAD vector, is an essential requisite for silencing competence. Indeed, the presence of the intact Shine-Dalgarno sequence positively affects asRNA stability and, hence, silencing effectiveness. Our observations will contribute to the understanding of the main determinants of silencing as exerted by asRNAs as well as provide useful support for the design of robust and efficient prokaryotic gene silencers. Copyright © 2010 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.
... may use a variety of instruments, shine bright lights directly at your eyes and request that you ... exam is complete, as daylight or other bright lights may be uncomfortable or cause blurred vision. Also, ...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stepinski, Dominique C.; Abdul, Momen; Youker, Amanda J.
2016-06-01
Argonne National Laboratory has developed a Mo-recovery and -purification system for the SHINE medical technologies process, which uses a uranyl sulfate solution for the accelerator-driven production of Mo-99. The objective of this effort is to reduce the processing time for the acidification of the Mo-99 product prior to loading onto a concentration column and concentration of the Mo-99 product solution. Two methods were investigated: (1) the replacement of the titania concentration column by an anion-exchange column to decrease processing time and increase the radioiodine-decontamination efficiency and (2) pretreatment of the titania sorbent to improve its effectiveness for the Mo-recovery andmore » -concentration columns. Promising results are reported for both methods.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aduszkiewicz, A.; Ali, Y.; Andronov, E. V.
Here, we present measurements ofmore » $$\\rho^0$$, $$\\omega$$ and K$$^{*0}$$ spectra in $$\\pi^{-} + $$C production interactions at 158 GeV/c and $$\\rho^0$$ spectra at 350 GeV/c using the NA61/SHINE spectrometer at the CERN SPS. Spectra are presented as a function of the Feynman's variable $$x_\\text{F}$$ in the range $$0 < x_\\text{F} < 1$$ and $$0 < x_\\text{F} < 0.5$$ for 158 GeV/c and 350 GeV/c respectively. Furthermore, we show comparisons with previous measurements and predictions of several hadronic interaction models. Our measurements are essential for a better understanding of hadronic shower development and for improving the modeling of cosmic ray air showers.« less
Aduszkiewicz, A.; Ali, Y.; Andronov, E. V.; ...
2017-09-20
Here, we present measurements ofmore » $$\\rho^0$$, $$\\omega$$ and K$$^{*0}$$ spectra in $$\\pi^{-} + $$C production interactions at 158 GeV/c and $$\\rho^0$$ spectra at 350 GeV/c using the NA61/SHINE spectrometer at the CERN SPS. Spectra are presented as a function of the Feynman's variable $$x_\\text{F}$$ in the range $$0 < x_\\text{F} < 1$$ and $$0 < x_\\text{F} < 0.5$$ for 158 GeV/c and 350 GeV/c respectively. Furthermore, we show comparisons with previous measurements and predictions of several hadronic interaction models. Our measurements are essential for a better understanding of hadronic shower development and for improving the modeling of cosmic ray air showers.« less
HARP and NA61 (SHINE) hadron production experiments
DOE Office of Scientific and Technical Information (OSTI.GOV)
Popov, Boris A.
2009-11-25
The hadroproduction experiments HARP and NA61 (SHINE) as well as their implications for neutrino physics are discussed. Recent HARP measurements have already been used for precise predictions of neutrino beams in K2K and MiniBooNE/SciBooNE experiments and are also being used to improve the atmospheric neutrino flux predictions and to help in the optimization of neutrino factory and super-beam designs. First preliminary data from NA61 are of significant importance for a precise prediction of a new neutrino beam at J-PARC to be used for the first stage of the T2K experiment. Both HARP and NA61 provide a large amount of inputmore » for validation and tuning of hadroproduction models in Monte-Carlo generators.« less
Recent results from the strong interactions program of NA61/SHINE
NASA Astrophysics Data System (ADS)
Pulawski, Szymon
2017-12-01
The NA61/SHINE experiment studies hadron production in hadron+hadron, hadron+nucleus and nucleus+nucleus collisions. The strong interactions program has two main purposes: study the properties of the onset of deconfinement and search for the signatures of the critical point of strongly interacting matter. This aim is pursued by performing a two-dimensional scan of the phase diagram by varying the energy/momentum (13A-158A GeV/c) and the system size (p+p, Be+Be, Ar+Sc, Xe+La) of the collisions. This publication reviews recent results from p+p, Be+Be and Ar+Sc interactions. Measured particle spectra are discussed and compared to NA49 results from Pb+Pb collisions. The results illustrate the progress towards scanning the phase diagram of strongly interacting matter.
Quality focus shining on corporate ethics.
2003-01-01
Compliance just scratches the surface of a comprehensive ethics policy. Being true to your mission is a critical component of governance responsibilities. Quality managers play an important role in feedback, implementation.
NASA Astrophysics Data System (ADS)
Fromm, Katharina M.
2011-02-01
Katharina M. Fromm explains how, as well as catalysis and jewellery, silver serves a myriad of medicinal applications - some of which are even behind poetic traditions such as throwing coins in wishing wells.
Sports Jobs Shine for Olympic Summer.
ERIC Educational Resources Information Center
Mariani, Matthew
1995-01-01
Gives information about opportunities, job tasks, and educational requirements of sports-related jobs in high school, college, and professional athletics: coaches, sports medicine specialists, managers, public relations specialists, and trainers. (SK)
An Interview with Stephen King.
ERIC Educational Resources Information Center
Janeczko, Paul
1980-01-01
The author of five best-selling novels, including "Carrie,""Salem's Lot,""The Shining,""The Stand," and "The Dead Zone," discusses the teaching of creative writing at high school and college levels. (DF)
A comparison of wearable fitness devices.
Kaewkannate, Kanitthika; Kim, Soochan
2016-05-24
Wearable trackers can help motivate you during workouts and provide information about your daily routine or fitness in combination with your smartphone without requiring potentially disruptive manual calculations or records. This paper summarizes and compares wearable fitness devices, also called "fitness trackers" or "activity trackers." These devices are becoming increasingly popular in personal healthcare, motivating people to exercise more throughout the day without the need for lifestyle changes. The various choices in the market for wearable devices are also increasing, with customers searching for products that best suit their personal needs. Further, using a wearable device or fitness tracker can help people reach a fitness goal or finish line. Generally, companies display advertising for these kinds of products and depict them as beneficial, user friendly, and accurate. However, there are no objective research results to prove the veracity of their words. This research features subjective and objective experimental results, which reveal that some devices perform better than others. The four most popular wristband style wearable devices currently on the market (Withings Pulse, Misfit Shine, Jawbone Up24, and Fitbit Flex) are selected and compared. The accuracy of fitness tracking is one of the key components for fitness tracking, and some devices perform better than others. This research shows subjective and objective experimental results that are used to compare the accuracy of four wearable devices in conjunction with user friendliness and satisfaction of 7 real users. In addition, this research matches the opinions between reviewers on an Internet site and those of subjects when using the device. Withings Pulse is the most friendly and satisfactory from the users' viewpoint. It is the most accurate and repeatable for step and distance tracking, which is the most important measurement of fitness tracking, followed by Fitbit Flex, Jawbone Up24, and Misfit Shine. In contrast, Misfit Shine has the highest score for design and hardware, which is also appreciated by users. From the results of experiments on four wearable devices, it is determined that the most acceptable in terms of price and satisfaction levels is the Withings Pulse, followed by the Fitbit Flex, Jawbone Up24, and Misfit Shine.
A Novel Method of Recording Motion
ERIC Educational Resources Information Center
Ben-Shalom, Amir; Gluck, Paul
2013-01-01
By attaching LEDs and lasers to moving objects, and shining their light on photochromic surfaces below them, we can display traces of many motions of interest in introductory physics courses and science museums.
A novel method of recording motion
NASA Astrophysics Data System (ADS)
Ben-Shalom, Amir; Gluck, Paul
2013-05-01
By attaching LEDs and lasers to moving objects, and shining their light on photochromic surfaces below them, we can display traces of many motions of interest in introductory physics courses and science museums.
Entrepreneurship Education: A Shining Opportunity for Collaboration.
ERIC Educational Resources Information Center
Ely, Vivien King
1984-01-01
Characteristics of successful entrepreneurs are technical competence, business management skills, self-confidence, and intellectual honesty. Entrepreneurship education can be planned to coincide with the individual's life stages and readiness for entrepreneurship. (SK)
None
2018-01-08
Solar photovoltaic (PV) systems can generate clean, cost-effective power anywhere the sun shines. This video shows how a PV panel converts the energy of the sun into renewable electricity to power homes and businesses.
Cicek, Mustafa; Mutlu, Ozal; Erdemir, Aysegul; Ozkan, Ebru; Saricay, Yunus; Turgut-Balik, Dilek
2013-06-01
One of the most important step in structure-based drug design studies is obtaining the protein in active form after cloning the target gene. In one of our previous study, it was determined that an internal Shine-Dalgarno-like sequence present just before the third methionine at N-terminus of wild type lactate dehydrogenase enzyme of Plasmodium falciparum prevent the translation of full length protein. Inspection of the same region in P. vivax LDH, which was overproduced as an active enzyme, indicated that the codon preference in the same region was slightly different than the codon preference of wild type PfLDH. In this study, 5'-GGAGGC-3' sequence of P. vivax that codes for two glycine residues just before the third methionine was exchanged to 5'-GGAGGA-3', by mimicking P. falciparum LDH, to prove the possible effects of having an internal SD-like sequence when expressing an eukaryotic protein in a prokaryotic system. Exchange was made by site-directed mutagenesis. Results indicated that having two glycine residues with an internal SD-like sequence (GGAGGA) just before the third methionine abolishes the enzyme activity due to the preference of the prokaryotic system used for the expression. This study emphasizes the awareness of use of a prokaryotic system to overproduce an eukaryotic protein.
Could GRB170817A be really correlated to an NS-NS merging?
NASA Astrophysics Data System (ADS)
Fargion, D.; Khlopov, M. Yu.; Oliva, P.
The exciting development of gravitational wave (GW) astronomy in the correlation of LIGO and VIRGO detection of GW signals makes possible to expect registration of effects of not only binary black hole (BH) coalescence but also binary neutron star (NS) merging accompanied by electromagnetic (gamma ray burst; GRB) signal. Here we consider the possibility that an NS, merging in an NS-NS or NS-BH system might be (soon) observed in correlation with any LIGO-VIRGO GWs detection. We analyze as an example the recent case of the short GRB170817A observed by Fermi and integral. The associated optical transient (OT) source in NGC4993 implies a rare near source, a consequent averaged large rate of such events (almost) compatible with expected NS-NS merging rate. However the expected beamed GRB (or short GRB) may be mostly aligned to a different direction than ours. Therefore, even soft GRB photons, spread more than hard ones, might be hardly able to shower to us. Nevertheless, a prompt spiraling electron turbine jet in largest magnetic fields, at the base of the NS-NS collapse, might shine by its tangential synchrotron radiation in spread way with its skimming photons shining in large open disk. The consequent solid angle for such soft disk gamma radiation may be large enough to be nevertheless often observed.
Phototherapy for jaundice; Bilirubin - bili lights; Neonatal care - bili lights; Newborn care - bili lights ... Phototherapy involves shining fluorescent light from the bili lights on bare skin. A specific wavelength of light can break down bilirubin into a form that ...
Watkins, Julie
2017-04-12
An interview's success depends on careful preparation and practice. A key aspect of this is researching your future employer and becoming familiar with the values of the trust or organisation where you want to work.
77 FR 39999 - Marine Mammals; File No. 17278
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-06
... James Shine, Ph.D., Harvard University School of Public Health, 401 Park Drive, 404H West, Boston... scientific research. DATES: Written, telefaxed, or email comments must be received on or before August 6...
Fixed-target hadron production experiments
NASA Astrophysics Data System (ADS)
Popov, Boris A.
2015-08-01
Results from fixed-target hadroproduction experiments (HARP, MIPP, NA49 and NA61/SHINE) as well as their implications for cosmic ray and neutrino physics are reviewed. HARP measurements have been used for predictions of neutrino beams in K2K and MiniBooNE/SciBooNE experiments and are also being used to improve predictions of the muon yields in EAS and of the atmospheric neutrino fluxes as well as to help in the optimization of neutrino factory and super-beam designs. Recent measurements released by the NA61/SHINE experiment are of significant importance for a precise prediction of the J-PARC neutrino beam used for the T2K experiment and for interpretation of EAS data. These hadroproduction experiments provide also a large amount of input for validation and tuning of hadron production models in Monte-Carlo generators.
2017-21 Miller's Son Shine Acres, Inc.
The EPA is providing notice of a proposed administrative penalty assessment for alleged violations of the Clean Water Act (Act). The EPA is also providing notice of the opportunity to comment on the proposed penalty assessment.
Hubble Finds a Lenticular Galaxy Standing Out in the Crowd
2017-12-08
A lone source shines out brightly from the dark expanse of deep space, glowing softly against a picturesque backdrop of distant stars and colorful galaxies. Captured by the NASA/ESA Hubble Space Telescope’s Advanced Camera for Surveys (ACS), this scene shows PGC 83677, a lenticular galaxy — a galaxy type that sits between the more familiar elliptical and spiral varieties. It reveals both the relatively calm outskirts and intriguing core of PGC 83677. Here, studies have uncovered signs of a monstrous black hole that is spewing out high-energy X-rays and ultraviolet light. Credit: NASA/ESA/Hubble; acknowledgements: Judy Schmidt (Geckzilla) NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Satellite Sees Holiday Lights Brighten Cities - Southern California and the Southwest
2017-12-08
City lights shine brighter during the holidays in the United States when compared with the rest of the year, as shown using a new analysis of daily data from the NASA-NOAA Suomi NPP satellite. Dark green pixels are areas where lights are 50 percent brighter, or more, during December. Because snow reflects so much light, the researchers could only analyze snow-free cities. They focused on the U.S. West Coast from San Francisco and Los Angeles, and cities south of a rough imaginary line from St. Louis to Washington, D.C. Credit: Jesse Allen, NASA’s Earth Observatory Read more: www.nasa.gov/content/goddard/satellite-sees-holiday-light....NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Satellite Sees Holiday Lights Brighten Cities - Washington, D.C., and Baltimore
2017-12-08
City lights shine brighter during the holidays in the United States when compared with the rest of the year, as shown using a new analysis of daily data from the NASA-NOAA Suomi NPP satellite. Dark green pixels are areas where lights are 50 percent brighter, or more, during December. Because snow reflects so much light, the researchers could only analyze snow-free cities. They focused on the U.S. West Coast from San Francisco and Los Angeles, and cities south of a rough imaginary line from St. Louis to Washington, D.C. Credit: Jesse Allen, NASA’s Earth Observatory Read more: www.nasa.gov/content/goddard/satellite-sees-holiday-light....NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Effectiveness of sheltering in buildings and vehicles for plutonium
DOE Office of Scientific and Technical Information (OSTI.GOV)
Engelmann, R.J.
1990-07-30
The purpose of this paper is to collect and present current knowledge relevant to the protection offered by sheltering against exposure to plutonium particles released to the atmosphere during accidents. For those many contaminants for which effects are linear with the airborne concentration, it is convenient to define a Dose Reduction Factor (DRF). In the past, the DRF has been defined as the ratio of the radiological dose that may be incurred within the shelter to that in the outdoors. As such, it includes the dose through shine from plumes aloft and from material deposited on the surface. For thismore » paper, which is concerned only with the inhalation pathway, the DRF is the ratio of the time-integrated concentration inside the shelter to that outdoors. It is important to note that the range over which effects are linear with concentration may be limited for many contaminants. Examples are when concentrations produce effects that are irreversible, or when concentrations are below effects threshold levels. 71 refs., 4 figs., 8 tabs.« less
Satellite Sees Holiday Lights Brighten Cities - United States
2017-12-08
City lights shine brighter during the holidays in the United States when compared with the rest of the year, as shown using a new analysis of daily data from the NASA-NOAA Suomi NPP satellite. Dark green pixels are areas where lights are 50 percent brighter, or more, during December. Because snow reflects so much light, the researchers could only analyze snow-free cities. They focused on the U.S. West Coast from San Francisco and Los Angeles, and cities south of a rough imaginary line from St. Louis to Washington, D.C. Credit: Jesse Allen, NASA’s Earth Observatory Read more: www.nasa.gov/content/goddard/satellite-sees-holiday-light... NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Satellite Sees Holiday Lights Brighten Cities - United States
2017-12-08
City lights shine brighter during the holidays in the United States when compared with the rest of the year, as shown using a new analysis of daily data from the NASA-NOAA Suomi NPP satellite. Dark green pixels are areas where lights are 50 percent brighter, or more, during December. Because snow reflects so much light, the researchers could only analyze snow-free cities. They focused on the U.S. West Coast from San Francisco and Los Angeles, and cities south of a rough imaginary line from St. Louis to Washington, D.C. Credit: Jesse Allen, NASA’s Earth Observatory Read more: www.nasa.gov/content/goddard/satellite-sees-holiday-light....NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Satellite Sees Holiday Lights Brighten Cities - Los Angeles
2017-12-08
City lights shine brighter during the holidays in the United States when compared with the rest of the year, as shown using a new analysis of daily data from the NASA-NOAA Suomi NPP satellite. Dark green pixels are areas where lights are 50 percent brighter, or more, during December. Because snow reflects so much light, the researchers could only analyze snow-free cities. They focused on the U.S. West Coast from San Francisco and Los Angeles, and cities south of a rough imaginary line from St. Louis to Washington, D.C. Credit: Jesse Allen, NASA’s Earth Observatory Read more: www.nasa.gov/content/goddard/satellite-sees-holiday-light....NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Satellite Sees Holiday Lights Brighten Cities - Atlanta
2017-12-08
City lights shine brighter during the holidays in the United States when compared with the rest of the year, as shown using a new analysis of daily data from the NASA-NOAA Suomi NPP satellite. Dark green pixels are areas where lights are 50 percent brighter, or more, during December. Because snow reflects so much light, the researchers could only analyze snow-free cities. They focused on the U.S. West Coast from San Francisco and Los Angeles, and cities south of a rough imaginary line from St. Louis to Washington, D.C. Credit: Jesse Allen, NASA’s Earth Observatory Read more: www.nasa.gov/content/goddard/satellite-sees-holiday-light....NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Satellite Sees Holiday Lights Brighten Cities - Florida
2017-12-08
City lights shine brighter during the holidays in the United States when compared with the rest of the year, as shown using a new analysis of daily data from the NASA-NOAA Suomi NPP satellite. Dark green pixels are areas where lights are 50 percent brighter, or more, during December. Because snow reflects so much light, the researchers could only analyze snow-free cities. They focused on the U.S. West Coast from San Francisco and Los Angeles, and cities south of a rough imaginary line from St. Louis to Washington, D.C. Credit: Jesse Allen, NASA’s Earth Observatory Read more: www.nasa.gov/content/goddard/satellite-sees-holiday-light....NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Satellite Sees Holiday Lights Brighten Cities - Texas and Louisiana
2017-12-08
City lights shine brighter during the holidays in the United States when compared with the rest of the year, as shown using a new analysis of daily data from the NASA-NOAA Suomi NPP satellite. Dark green pixels are areas where lights are 50 percent brighter, or more, during December. Because snow reflects so much light, the researchers could only analyze snow-free cities. They focused on the U.S. West Coast from San Francisco and Los Angeles, and cities south of a rough imaginary line from St. Louis to Washington, D.C. Credit: Jesse Allen, NASA’s Earth Observatory Read more: www.nasa.gov/content/goddard/satellite-sees-holiday-light....NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Dose estimation and dating of pottery from Turkey
NASA Astrophysics Data System (ADS)
Altay Atlıhan, M.; Şahiner, Eren; Soykal Alanyalı, Feriştah
2012-06-01
The luminescence method is a widely used technique for environmental dosimetry and dating archaeological, geological materials. In this study, equivalent dose (ED) and annual dose rate (AD) of an archaeological sample were measured. The age of the material was calculated by means of equivalent dose divided by the annual dose rate. The archaeological sample was taken from Antalya, Turkey. Samples were prepared by the fine grain technique and equivalent dose was found using multiple-aliquot-additive-dose (MAAD) and single aliquot regeneration (SAR) techniques. Also the short shine normalization-MAAD and long shine normalization-MAAD were applied and the results of the methods were compared with each other. The optimal preheat temperature was found to be 200 °C for 10 min. The annual doses of concentrations of the major radioactive isotopes were determined using a high-purity germanium detector and a low-level alpha counter. The age of the sample was found to be 510±40 years.
Remanent Activation in the Mini-SHINE Experiments
DOE Office of Scientific and Technical Information (OSTI.GOV)
Micklich, Bradley J.
2015-04-16
Argonne National Laboratory is assisting SHINE Medical Technologies in developing a domestic source of the medical isotope 99Mo through the fission of low-enrichment uranium in a uranyl sulfate solution. In Phase 2 of these experiments, electrons from a linear accelerator create neutrons by interacting in a depleted uranium target, and these neutrons are used to irradiate the solution. The resulting neutron and photon radiation activates the target, the solution vessels, and a shielded cell that surrounds the experimental apparatus. When the experimental campaign is complete, the target must be removed into a shielding cask, and the experimental components must bemore » disassembled. The radiation transport code MCNPX and the transmutation code CINDER were used to calculate the radionuclide inventories of the solution, the target assembly, and the shielded cell, and to determine the dose rates and shielding requirements for selected removal scenarios for the target assembly and the solution vessels.« less
NASA Astrophysics Data System (ADS)
Abgrall, N.; Aduszkiewicz, A.; Ajaz, M.; Ali, Y.; Andronov, E.; Antićić, T.; Antoniou, N.; Baatar, B.; Bay, F.; Blondel, A.; Blümer, J.; Bogomilov, M.; Brandin, A.; Bravar, A.; Brzychczyk, J.; Bunyatov, S. A.; Busygina, O.; Christakoglou, P.; Ćirković, M.; Czopowicz, T.; Davis, N.; Debieux, S.; Dembinski, H.; Deveaux, M.; Diakonos, F.; Di Luise, S.; Dominik, W.; Dumarchez, J.; Dynowski, K.; Engel, R.; Ereditato, A.; Feofilov, G. A.; Fodor, Z.; Garibov, A.; Gaździcki, M.; Golubeva, M.; Grebieszkow, K.; Grzeszczuk, A.; Guber, F.; Haesler, A.; Hasegawa, T.; Hervé, A. E.; Hierholzer, M.; Igolkin, S.; Ivashkin, A.; Johnson, S. R.; Kadija, K.; Kapoyannis, A.; Kaptur, E.; Kisiel, J.; Kobayashi, T.; Kolesnikov, V. I.; Kolev, D.; Kondratiev, V. P.; Korzenev, A.; Kowalik, K.; Kowalski, S.; Koziel, M.; Krasnoperov, A.; Kuich, M.; Kurepin, A.; Larsen, D.; László, A.; Lewicki, M.; Lyubushkin, V. V.; Maćkowiak-Pawłowska, M.; Maksiak, B.; Malakhov, A. I.; Manić, D.; Marcinek, A.; Marino, A. D.; Marton, K.; Mathes, H.-J.; Matulewicz, T.; Matveev, V.; Melkumov, G. L.; Messerly, B.; Mills, G. B.; Morozov, S.; Mrówczyński, S.; Nagai, Y.; Nakadaira, T.; Naskręt, M.; Nirkko, M.; Nishikawa, K.; Panagiotou, A. D.; Paolone, V.; Pavin, M.; Petukhov, O.; Pistillo, C.; Płaneta, R.; Popov, B. A.; Posiadała-Zezula, M.; Puławski, S.; Puzović, J.; Rauch, W.; Ravonel, M.; Redij, A.; Renfordt, R.; Richter-Wąs, E.; Robert, A.; Röhrich, D.; Rondio, E.; Roth, M.; Rubbia, A.; Rumberger, B. T.; Rustamov, A.; Rybczynski, M.; Sadovsky, A.; Sakashita, K.; Sarnecki, R.; Schmidt, K.; Sekiguchi, T.; Selyuzhenkov, I.; Seryakov, A.; Seyboth, P.; Sgalaberna, D.; Shibata, M.; Słodkowski, M.; Staszel, P.; Stefanek, G.; Stepaniak, J.; Ströbele, H.; Šuša, T.; Szuba, M.; Tada, M.; Taranenko, A.; Tefelska, A.; Tefelski, D.; Tereshchenko, V.; Tsenov, R.; Turko, L.; Ulrich, R.; Unger, M.; Vassiliou, M.; Veberič, D.; Vechernin, V. V.; Vesztergombi, G.; Vinogradov, L.; Wilczek, A.; Włodarczyk, Z.; Wojtaszek-Szwarc, A.; Wyszyński, O.; Yarritu, K.; Zambelli, L.; Zimmerman, E. D.; Friend, M.; Galymov, V.; Hartz, M.; Hiraki, T.; Ichikawa, A.; Kubo, H.; Matsuoka, K.; Murakami, A.; Nakaya, T.; Suzuki, K.; Tzanov, M.; Yu, M.
2016-11-01
Measurements of particle emission from a replica of the T2K 90 cm-long carbon target were performed in the NA61/SHINE experiment at CERN SPS, using data collected during a high-statistics run in 2009. An efficient use of the long-target measurements for neutrino flux predictions in T2K requires dedicated reconstruction and analysis techniques. Fully-corrected differential yields of π ^± -mesons from the surface of the T2K replica target for incoming 31 GeV/ c protons are presented. A possible strategy to implement these results into the T2K neutrino beam predictions is discussed and the propagation of the uncertainties of these results to the final neutrino flux is performed.
Patil, Harshal Ashok; Chitko, Shrikant Shrinivas; Kerudi, Veerendra Virupaxappa; Maheshwari, Amit Ratanlal; Patil, Neeraj Suresh; Tekale, Pawankumar Dnyandeo; Gore, Ketan Ashorao; Zope, Amit Ashok
2016-08-01
Reflectivity of an object is a good parameter for surface finish. As the patient evaluates finishing as a function of gloss/reflectivity/shine an attempt is made here to evaluate changes in surface finish with custom made reflectometer. The aim of the present study was to study the effect of various procedures during orthodontic treatment on the shine of enamel, using a custom made reflectometer. Sixty one extracted premolars were collected and each tooth was mounted on acrylic block. Reflectivity of the teeth was measured as compared to standard before any procedure. One tooth was kept as standard throughout the study. Sixty teeth were acid etched. Reflectivity was measured on custom made reflectometer and readings recorded. Same procedure was repeated after debonding. Then 60 samples were divided into three groups: Group 1 - Tungsten Carbide, Group 2 - Astropol, Group 3- Sof-Lex disc depending upon the finishing method after debonding and reflectivity was measured. The mean percentage of reflectivity after acid etching was 31.4%, debonding 45.5%, Tungsten carbide bur finishing (Group 1) was 58.3%, Astropol (Group 2) 72.8%, and Sof-Lex disc (Group 3) 84.4% as that to the standard. There was statistically very highly significant (p<0.001) difference in reflectivity restored by the three finishing materials in the study. Thus, the light reflection was better in Group 3> Group 2> Group 1. The primary goal was to restore the enamel to its original state after orthodontic treatment. The methods tested in this study could not restore the original enamel reflectivity.
78 FR 19537 - SHINE Medical Technologies, Inc.; Exemption
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-01
... under 10 CFR 2.101(a)(5), as proposed, an exemption to the regulations is required. Given the dependency... requested is not for an exemption to a 10 CFR part 50 regulation, given the dependency of docketing a...
Sun Shines in High-Energy X-rays
2014-12-22
X-rays stream off the sun in this first picture of the sun, overlaid on a picture taken by NASA Solar Dynamics Observatory SDO, taken by NASA NuSTAR. The field of view covers the west limb of the sun.
Barendt, Pamela A.; Shah, Najaf A.; Barendt, Gregory A.; Kothari, Parth A.; Sarkar, Casim A.
2013-01-01
While the ribosome has evolved to function in complex intracellular environments, these contexts do not easily allow for the study of its inherent capabilities. We have used a synthetic, well-defined, Escherichia coli (E. coli)-based translation system in conjunction with ribosome display, a powerful in vitro selection method, to identify ribosome binding sites (RBSs) that can promote the efficient translation of messenger RNAs (mRNAs) with a leader length representative of natural E. coli mRNAs. In previous work, we used a longer leader sequence and unexpectedly recovered highly efficient cytosine-rich sequences with complementarity to the 16S ribosomal RNA (rRNA) and similarity to eukaryotic RBSs. In the current study, Shine-Dalgarno (SD) sequences were prevalent but non-SD sequences were also heavily enriched and were dominated by novel guanine- and uracil-rich motifs which showed statistically significant complementarity to the 16S rRNA. Additionally, only SD motifs exhibited position-dependent decreases in sequence entropy, indicating that non-SD motifs likely operate by increasing the local concentration of ribosomes in the vicinity of the start codon, rather than by a position-dependent mechanism. These results further support the putative generality of mRNA-rRNA complementarity in facilitating mRNA translation, but also suggest that context (e.g., leader length and composition) dictates the specific subset of possible RBSs that are used for efficient translation of a given transcript. PMID:23427812
Changing the color of textiles with realistic visual rendering
NASA Astrophysics Data System (ADS)
Hébert, Mathieu; Henckens, Lambert; Barbier, Justine; Leboulleux, Lucie; Page, Marine; Roujas, Lucie; Cazier, Anthony
2015-03-01
Fast and easy preview of a fabric without having to produce samples would be very profitable for textile designers, but remains a technological challenge. As a first step towards this objective, we study the possibility of making images of a real sample, and changing virtually the colors of its yarns while preserving the shine and shadow texture. We consider two types of fabrics: Jacquard weave fabrics made of polyester warp and weft yarns of different colors, and satin ribbons made of polyester and metallic yarns. For the Jacquard fabric, we make a color picture with a scanner on a sample in which the yarns have contrasted colors, threshold this image in order to distinguish the pixels corresponding to each yarn, and accordingly modify their hue and chroma values. This method is simple to operate but do not enable to simulate the angle-dependent shine. A second method, tested on the satin ribbon made of black polyester and achromatic metallic yarns, is based on polarized imaging. We analyze the polarization state of the reflected light which is different for dielectric and metallic materials illuminated by polarized light. We then add a fixed color value to the pixels representing the polyester yarns and modify the hue and chroma of the pixels representing the metallic yarns. This was performed for many incident angles of light, in order to render the twinkling effect displayed by these ribbons. We could verify through a few samples that the simulated previews reproduce real pictures with visually acceptable accuracy.
ERIC Educational Resources Information Center
Bragg, Debra D.; Soler, Maria Claudia
2016-01-01
This chapter discusses methods and measures that are needed to conduct research on newly developing Applied Baccalaureate degrees that enable students to transfer applied college credits heretofore considered terminal to bachelor's degree programs.
ERIC Educational Resources Information Center
Butler, Judy; Grier, Terry B.
2000-01-01
A few years ago, the Williamson County (Tennessee) School District developed a strategic plan to encourage volunteers' participation. The plan includes a vision, goals, and objectives; strategies for increasing community involvement; recognition for all volunteers (via the Shining Apple Award); and program evaluation. (MLH)
2005-12-13
In visible light, the bulk of our Milky Way galaxy stars are eclipsed behind thick clouds of galactic dust and gas. But to the infrared eyes of NASA Spitzer Space Telescope, distant stars and dust clouds shine with unparalleled clarity and color.
The Chelyabinsk Meteorite Hits an Anomalous Zone in the Urals
NASA Astrophysics Data System (ADS)
Kochemasov, G. G.
2013-09-01
The Chelyabinsk meteorite is "strange" because it hits an area in the Urals where anomalous events are observed: shining skies, light balls, UFOs, electrphonic bolids. The area tectonically occurs at the intersection of two fold belts: Urals and Timan.
NASA Astrophysics Data System (ADS)
Bhuvaneswari, R.; Nagarajan, V.; Chandiramouli, R.
2018-01-01
The density functional theory (DFT) method with non-equilibrium Green's function (NEGF) method is used to study the electronic properties of the graphyne nanotube device. The graphyne nanotube is used as a base material to graft photochromic spiropyran and merocyanine molecules. The current voltage characteristics clearly give the insights on the switching properties of spiropyran and merocyanine grafted graphyne device. The findings show that spiropyran grafted graphyne device as ON state and merocyanine grafted graphyne device as an OFF state device. Moreover, upon shining light of proper wavelength, the spiropyran/merocyanine grafted graphyne nanotube device can be used as a switch.
ERIC Educational Resources Information Center
Kennedy, Mike
2000-01-01
Discusses how schools and universities can save energy and money by evaluating lighting systems and changing behaviors. Retrofitting older buildings with better lighting technology and use of natural light are examined. An example of an energy conservation education program to reduce energy waste is highlighted. (GR)
2010-07-28
A star-forming region shines from the considerable distance of more than 30,000 light-years away in the upper left of this image from NASA Spitzer Space Telescope. This image is a combination of data from Spitzer and the Two Micron All Sky Survey.
Razani, Nooshin; Kohn, Michael A; Wells, Nancy M; Thompson, Doug; Hamilton Flores, Hanna; Rutherford, George W
2016-11-01
Contact with nature improves human health; stress reduction is a mediating pathway. Stay Healthy in Nature Everyday (SHINE) is a stress reduction and health promotion intervention for low-income families at an urban Federally Qualified Health Center. We plan to evaluate two service-delivery models for SHINE and present here the intervention design and evaluation protocol. Behavioral change theory and environmental education literature informed the intervention. Outcomes were selected after review of the literature and field tested procedures to determine what was feasible and ethical in a busy clinic serving vulnerable populations. We designed a randomized controlled trial to examine two levels of intensity in behavioral counseling about the health benefits of nature. Dyads consisting of a caregiver and a child aged 4 to 18 who access our pediatric primary care center are eligible. All dyads receive a pediatrician's recommendation to visit parks to experience nature and written resources (a "park prescription"). The intervention group receives added case management and an invitation to three group outings into nature with transportation, meals and activities provided. Primary outcomes measured at baseline, one month and three months post-enrollment are caregiver stress measured by PSS-10 score and salivary α-amylase; secondary outcomes are park prescriptions adherence, physical activity recorded by pedometer and journaling, loneliness, family cohesion and affinity to nature as measured by a validated scales. Both groups receive incentives to participation. Our intervention represents a feasible integration of recent research findings on the health benefits of nature and primary care practice. Copyright © 2016 Elsevier Inc. All rights reserved.
Graphical introduction to chromospheric line formation
NASA Astrophysics Data System (ADS)
Rutten, Rob
2012-03-01
The basics of chromospheric line formation theory were laid out in the 1960s and 1970s by e.g., Thomas, Avrett, Hummer, Jefferies, Mihalas, Shine, Milkey. Since then there has been a long silence, without much progress in understanding the chromosphere or its diagnostics. At present, the situation changes thanks to better ground-based observing, space-based monitoring, and increasingly realistic numerical simulations. There is a now a strong need to revamp classical one-dimensional static modeling as basis for chromospheric line interpretation into 3D dynamic understanding of the major diagnostics, including IRIS's Mg II h&k. In this introduction I aim to explain the old wisdom in tutorial fashion, using cartoons and graphs as means towards an intuitive grasp of fads and fallacies of chromospheric line formation.
Design Through Integration of On-Board Calibration Device with Imaging Spectroscopy Instruments
NASA Technical Reports Server (NTRS)
Stange, Michael
2012-01-01
The main purpose of the Airborne Visible and Infrared Imaging Spectroscopy (AVIRIS) project is to "identify, measure, and monitor constituents of the Earth's surface and atmosphere based on molecular absorption and particle scattering signatures." The project designs, builds, and tests various imaging spectroscopy instruments that use On-Board Calibration devices (OBC) to check the accuracy of the data collected by the spectrometers. The imaging instrument records the spectral signatures of light collected during flight. To verify the data is correct, the OBC shines light which is collected by the imaging spectrometer and compared against previous calibration data to track spectral response changes in the instrument. The spectral data has the calibration applied to it based on the readings from the OBC data in order to ensure accuracy.
Coatings for fresh fruits and vegetables
USDA-ARS?s Scientific Manuscript database
Coatings (waxes) are applied to apples, citrus, stone fruits, avocados, tomatoes and cucumbers prior to marketing in order to reduce water loss and shrinkage, create a modified atmosphere inside the produce, slow down senescence and ageing, impart shine, and allow for better quality and marketing pr...
The Social Justice Perspective
ERIC Educational Resources Information Center
Loewen, Gladys; Pollard, William
2010-01-01
This article shines an important light on the continuing struggle of disabled people for dignity, citizenship rights, and access to the marketplace. Common threads bind the struggle for basic human rights among disenfranchised groups, offer experience and approaches to facilitate change, and move society towards social justice. The philosophy…
ERIC Educational Resources Information Center
Smith, Susan
2012-01-01
Today's chief diversity officer could be tomorrow's university president, says Dr. Damon Williams. The author profiles Damon Williams who shines as sought-after expert on issues surrounding higher education inclusion. As head of a diversity division with an eight-figure budget at Wisconsin's flagship state university, Williams oversees four…
Self-determination theory and weight loss in a Diabetes Prevention Program translation trial.
Trief, Paula M; Cibula, Donald; Delahanty, Linda M; Weinstock, Ruth S
2017-06-01
We examined self-determination theory (SDT) and weight loss, and hypothesized that the Diabetes Prevention Program's (DPP) intervention would result in an increase in autonomous regulation of motivation (AR) in participants. Further, that those with higher AR, and those who perceived educators as supporting SDT-defined needs, would lose more weight. Support, Health Information, Nutrition and Exercise (SHINE) Study data (N = 257) were analyzed. SHINE was a randomized, controlled DPP translation trial (2-years, telephonic, primary care staff). Autonomous motivation in males increased significantly, while females showed no change. Males with high AR, but not females, lost more weight. However, the significance of these relationships varied over time. Participants who perceived educators as more supportive of psychological needs lost more weight (especially males). However, effect of support on weight loss was not mediated by AR change. Autonomous motivation and educator support are relevant to male weight loss. Future research might develop interventions to enhance autonomous motivation and educator support, and understand change pathways.
Katayama-Ikegami, Ayako; Suehiro, Yuka; Katayama, Takane; Jindo, Kazushi; Itamura, Hiroyuki; Esumi, Tomoya
2017-12-01
Polyphenol oxidases (PPOs) catalyze browning reactions in various plant organs, therefore controlling the reactions is important for the food industry. PPOs have been assumed to be involved in skin browning of white grape cultivars; however, the molecular mechanism underlying PPO-mediated browning process remains elusive. We have recently identified a new PPO gene named VvPPO2 from "Shine Muscat" (Vitis labruscana Bailey × V. vinifera L.), and have shown that the gene is transcribed at a higher level than the previously identified VvPPO1 in browning, physiologically disordered berry skins at the maturation stage. In this study, we expressed VvPPO2 in Escherichia coli and, using the purified preparation, revealed unique physicochemical characteristics of the enzyme. Our study opens up a way to not only understand the berry skin browning process but also to elucidate the enzymatic maturation process of grape PPOs.
Coppa, N.V.
1993-08-24
A method is described of producing superconducting microcircuits comprising the steps of: depositing a thin film of Ba[sub 2]Cu[sub 3]O[sub 5+x](O < x < 1) onto a substrate; depositing a thin film of a dopant onto said thin film of Ba[sub 2]Cu[sub 3]O[sub 5+x]; depositing a photoresist onto said thin film of a dopant; shining light through a mask containing a pattern for a desired circuit configuration and onto said photoresist; developing said photoresist to remove portions of said photoresist shined by the light and to selectively expose said dopant film; etching said selectively exposed dopant film from said thin film of Ba[sub 2]Cu[sub 3]O[sub 5+x] to form a pattern of dopant; and heating said substrate at a temperature and for a period of time sufficient to diffuse and react said pattern of dopant with said thin film of Ba[sub 2]Cu[sub 3]O[sub 5+x].
Muhammad, Education, and Finitude
ERIC Educational Resources Information Center
Ghiloni, Aaron J.
2016-01-01
Biographies of Prophet Muhammad extol his distinguished life, noting his achievements as a healer, diplomat, and general. Among these successes, it is especially as a teacher that Muhammad's exemplarity shines through. However, Muhammad's educational leadership arose not only out of his considerable capacities but also out of his limitations.…
Two Crowd Control Case Studies
2007-08-01
Soldiers shine powerful lights into the detox center from 110-foot towers. The army steadily pushes its side of the barriers forward, tightening their...for Mo- hawks. Water fight - not effective for either side. Army locks and loads - effective for Army 26 Sep 90 At the local detox center in
ERIC Educational Resources Information Center
Cannon, Michael, Ed.
2002-01-01
This document presents four issues of the Texas Association for the Gifted and Talented's quarterly publication, each of which focused on a particular theme: (1) instructional grouping options; (2) humanities and gifted students; (3) math and science; and (4) a 25th anniversary issue, "Silver Legacy: Shining on the Future for Gifted…
The Brightest in Solar Homes to Shine in Public Tour
open to the public Oct. 19 as part of the National Solar Home Tour sponsored by the American Solar are taking part in this year's national tour. Locally the homes will be open to the public from 10 a.m
Induced Currents in Multiple Resonant Scattering
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ruby, Stanley L
We will describe here some results from a MRS scattering model designed to be appropriate for slow resonant scattering. This temporal model is based squarely in induced currents in individual nuclei; a natural consequence is that reradiation into 4{pi} is natural, and does not involve special mechanisms like spin-flips or imperfections of the lattice. Driven by these ideas, we have been able to do experiments where the 4{pi}-shine decay rate around the scattering (FS) slabs is measured simultaneously with the FS rate. Our SS scattering slabs are simple as possible--no hyperfine fields, no crystal structure, and quite static in time.more » Get mainly the one important set of currents jp, an associated FS field Ep, and finally an associated beamlike intensity R{sub fs}(t). But in addition, each current, even jp, contributes to the 4{pi}-shine intensity. This gives quantitative agreement with R{sub 4{pi}}(t), which is rather more complicated than the simple e{sup {minus}t} one might first expect. MRS predicts another set of currents ju, with an associated 4{pi} intensity R{sub 4{pi}}(t). The modifiers refer to unphased and phased. With static SS slabs, this branch is weak, and can be neglected. Driven by these ideas, we have prepared scattering samples where the atoms holding the currents are being stirred about (by diffusion) rather rapidly. This provides a method for dephasing the jp, but also provides a generation rate for ju. The experimental data is not of great quality at this early stage. But the present rough MRS calculations fit easily.« less
World-wide amateur observations
NASA Astrophysics Data System (ADS)
Eversberg, T.; Aldoretta, E. J.; Knapen, J. H.; Moffat, A. F. J.; Morel, T.; Ramiaramanantsoa, T.; Rauw, G.; Richardson, N. D.; St-Louis, N.; Teodoro, M.
For some years now, spectroscopic measurements of massive stars in the amateur domain have been fulfilling professional requirements. Various groups in the northern and southern hemispheres have been established, running successful professional-amateur (ProAm) collaborative campaigns, e.g., on WR, O and B type stars. Today high quality data (echelle and long-slit) are regularly delivered and corresponding results published. Night-to-night long-term observations over months to years open a new opportunity for massive-star research. We introduce recent and ongoing sample campaigns (e.g. ɛ Aur, WR 134, ζ Pup), show respective results and highlight the vast amount of data collected in various data bases. Ultimately it is in the time-dependent domain where amateurs can shine most.
Pictogram Evaluation and Authoring Collaboration Environment
Kim, Hyeoneui; Tamayo, Dorothy; Muhkin, Michael; Kim, Jaemin; Lam, Julius; Ohno-Machado, Lucila; Aronoff-Spencer, Eliah
2012-01-01
Studies showed benefits of using pictograms in health communication such as improved recall and comprehension of health instructions. Pictograms are culturally sensitive thus need to be rigorously validated to ensure they convey the intended meaning correctly to the targeted population. The infeasibility of manually creating pictograms and the lack of robust means to store and validate pictograms are potential barriers to the wider adoption of pictograms in health communication. To address these challenges, we created an open access web-based tool, PEACE (Pictogram Evaluation and Authoring Collaboration Environment) as a part of SHINE (Sustainable Health Informatics and Networking Environment) initiatives. We report the development process and the preliminary evaluation results of PEACE in this paper. PMID:24199088
NASA Astrophysics Data System (ADS)
von Oertzen, Timo; Ghisletta, Paolo; Lindenberger, Ulman
Variability across and within individuals is a fundamental property of adult age changes in behavior [20, 21, 24]. Some people seem young for their age, others seem old; shining examples of older individuals who maintained high levels of intellectual functioning well into very old age, such as Johann Wolfgang von Goethe or Sophocles, stand in contrast to individuals whose cognitive resources are depleted by the time they reach later adulthood. A similar contrast exists between different intellectual abilities. For example, if one looks at the speed needed to identify and discriminate between different percepts, one is likely to find monotonic decline after late adolescence and early adulthood.
New intracellular activities of matrix metalloproteinases shine in the moonlight.
Jobin, Parker G; Butler, Georgina S; Overall, Christopher M
2017-11-01
Adaption of a single protein to perform multiple independent functions facilitates functional plasticity of the proteome allowing a limited number of protein-coding genes to perform a multitude of cellular processes. Multifunctionality is achievable by post-translational modifications and by modulating subcellular localization. Matrix metalloproteinases (MMPs), classically viewed as degraders of the extracellular matrix (ECM) responsible for matrix protein turnover, are more recently recognized as regulators of a range of extracellular bioactive molecules including chemokines, cytokines, and their binders. However, growing evidence has convincingly identified select MMPs in intracellular compartments with unexpected physiological and pathological roles. Intracellular MMPs have both proteolytic and non-proteolytic functions, including signal transduction and transcription factor activity thereby challenging their traditional designation as extracellular proteases. This review highlights current knowledge of subcellular location and activity of these "moonlighting" MMPs. Intracellular roles herald a new era of MMP research, rejuvenating interest in targeting these proteases in therapeutic strategies. This article is part of a Special Issue entitled: Matrix Metalloproteinases edited by Rafael Fridman. Copyright © 2017 Elsevier B.V. All rights reserved.
Patients' rights in decision making: the case for personalism versus paternalism in health care.
Schain, W S
1980-08-15
The purpose of this presentation is to shine a psychological spotlight on the role of the breast cancer patient in the process of her decision making about her medical care and the specific influence that the nature of the physician-patient interaction has on that behavior. The vision of the parental physician as unilateral authority in decisions about health care is dimming. The picture is being supplanted by a new image that promotes a view of personalism and a concept of "shared responsibility." The wave of consumerism is washing the shores of medical practice, and women are establishing their beachhead. Women are demonstrating their knowledge, their competence, and their responsibility in exercising decisions about their medical treatments and the quality of their survival. Therefore, it is essential to educate patients to exhibit informed consumer behavior and encourage physicians to recognize the value of a patient's participation. Such collaborative endeavors could result in increased patient satisfaction, reduced burdens for the physician, and preserved patients' feelings of individuality, autonomy, and sense of personal dignity.
Computational toxicology: Its essential role in reducing drug attrition.
Naven, R T; Louise-May, S
2015-12-01
Predictive toxicology plays a critical role in reducing the failure rate of new drugs in pharmaceutical research and development. Despite recent gains in our understanding of drug-induced toxicity, however, it is urgent that the utility and limitations of our current predictive tools be determined in order to identify gaps in our understanding of mechanistic and chemical toxicology. Using recently published computational regression analyses of in vitro and in vivo toxicology data, it will be demonstrated that significant gaps remain in early safety screening paradigms. More strategic analyses of these data sets will allow for a better understanding of their domain of applicability and help identify those compounds that cause significant in vivo toxicity but which are currently mis-predicted by in silico and in vitro models. These 'outliers' and falsely predicted compounds are metaphorical lighthouses that shine light on existing toxicological knowledge gaps, and it is essential that these compounds are investigated if attrition is to be reduced significantly in the future. As such, the modern computational toxicologist is more productively engaged in understanding these gaps and driving investigative toxicology towards addressing them. © The Author(s) 2015.
ERIC Educational Resources Information Center
Bondy, Elizabeth; Hambacher, Elyse
2016-01-01
Care is in the eyes of the receiver; it doesn't exist unless those being cared for experience it. The authors describe culturally relevant critical teacher care, an approach that considers the effects of students' cultural and socioeconomic conditions and that helps teachers find ways to show care to every learner--especially those from oppressed…
Problem-Solving Test: Expression Cloning of the Erythropoietin Receptor
ERIC Educational Resources Information Center
Szeberenyi, Jozsef
2008-01-01
Terms to be familiar with before you start to solve the test: cytokines, cytokine receptors, cDNA library, cDNA synthesis, poly(A)[superscript +] RNA, primer, template, reverse transcriptase, restriction endonucleases, cohesive ends, expression vector, promoter, Shine-Dalgarno sequence, poly(A) signal, DNA helicase, DNA ligase, topoisomerases,…
Playing for the Breaks: Insurgent Mistakes
2009-01-01
general, insurgencies that survive their “ birth ”—their appear- ance as an armed challenger—and possess a degree of competence often experience a...Bangkok: White Lotus Press, 2007), 291. 37. Gordon H. McCormick, From the Sierra to the Cities: The Urban Campaign of the Shining Path (San- ta
A Framework For Fault Tolerance In Virtualized Servers
2016-06-01
effects into the system. Decrease in performance, the expansion in the total system size and weight, and a hike in the system cost can be counted in... benefit also shines out in terms of reliability. 41 4. How Data Guard Synchronizes Standby Databases Primary and standby databases in Oracle Data
School Psychology Awareness: Helping Every Student Shine
ERIC Educational Resources Information Center
Cowan, Katherine C.; Cohn, Andrea
2010-01-01
The role of the school psychologist is strategically placed at the epicenter of a child's life. Not only do school psychologists provide direct services to the students at their schools, but they also work and collaborate with teachers, parents, peers, administrators, and community providers. Consequently, the potential impact that school…
Is the Shine off the A.P. Apple?
ERIC Educational Resources Information Center
Hurwitz, Nina; Hurwitz, Sol
2003-01-01
Describes challenges facing College Board's efforts to expand Advanced Placement (A.P.) courses to provide equal access to previously underserved low-performing urban and rural school students while maintaining the program's high academic standards. Includes list of strategies school boards can use to achieve greater access to A.P. courses while…
ERIC Educational Resources Information Center
Miller, Howard M.
1999-01-01
Argues that teachers must shine the brightest light they can onto ignorance. Discusses reasons why gay and lesbian issues need to be addressed in the curriculum. Describes helpful resources (including Web sites, a video, and nonfiction and fiction books) for raising teachers' own awareness, and for use in both preservice and regular classrooms.…
Early Childhood Workforce Index, 2016
ERIC Educational Resources Information Center
Whitebook, Marcy; McLean, Caitlin; Austin, Lea J. E.
2016-01-01
The State of the Early Childhood Workforce (SECW) Initiative is a groundbreaking multi-year project to shine a steady spotlight on the nation's early childhood workforce. The SECW Initiative is designed to challenge entrenched ideas and policies that maintain an inequitable and inadequate status quo for early educators and for the children and…
Languages of Domination and Rebellion in Highland Peru.
ERIC Educational Resources Information Center
Isbell, Billie Jean
1985-01-01
Andean society is polarized into two key segments: the national Spanish-speaking culture and the native Quechua-speaking culture. Each group ignores or reconstructs history in order to perpetuate its deep-seated prejudices. A group called "The Shining Path" is trying to transform both cultures through violent revolution. (RM)
The Shining Path and the Future of Peru
1990-03-01
prospect of a steady income. Most are Quechua speakers, often exclusively so, and have the same cultural and economic back- grounds as Sendero’s rural...speak Quechua . This gulf, which often makes even simple communication difficult, is not bridged by a profes- sional corps of noncommissioned officers
Trends in wilderness recreation use characteristics
Alan E. Watson; David N. Cole; Joseph W. Roggenbuck
1995-01-01
Recent studies at the Leopold Institute have included analysis of use and user trends at the Boundary Waters Canoe Area Wilderness, Desolation Wilderness, Shining Rock Wilderness, the Bob Marshall Wilderness Complex, Great Smoky Mountains National Park and Eagle Cap Wilderness. Some sociodemographics, like age, education, and the proportion of female visitors, have...
When Stars Align: Teachers & Students Shine Brighter
ERIC Educational Resources Information Center
Baker, Sheila F.; Willis, Jana
2016-01-01
A new teacher enters the classroom for the first time equipped with teaching strategies, technology-integration models, and classroom experiences acquired during his or her teacher preparation program. These new teachers are often unaware that down the hall exists their greatest resource for today's technologies and their strongest potential…
ERIC Educational Resources Information Center
Riddle, Bob
2004-01-01
This is another great month for evening observing as four planets continue to remain easily visible. Venus, Mars, and Saturn can be viewed over the western horizon, and Jupiter is shining high over the southeastern horizon. Opportunities will also exist for using binoculars or low-power telescopes to observe conjunctions between the planets, the…
HCA award winner's passion and enthusiasm shine through.
Cole, Elaine
2017-05-24
A healthcare assistant who significantly improved care for people with learning disabilities through an individualised, gentler approach to taking blood has been recognised with a prestigious RCNi Nurse Award. Cemlyn Roberts, who works for Betsi Cadwaladr University Health Board in Wales, won the RCN Healthcare Assistant award category.
SHINE Vacuum Pump Test Verification
DOE Office of Scientific and Technical Information (OSTI.GOV)
Morgan, Gregg A; Peters, Brent
2013-09-30
Normetex pumps used world-wide for tritium service are no longer available. DOE and other researchers worldwide have spent significant funds characterizing this pump. Identification of alternate pumps is required for performance and compatibility with tritium gas. Many of the pumps that could be used to meet the functional performance requirements (e.g. pressure and flow conditions) of the Normetex pump have features that include the use of polymers or oils and greases that are not directly compatible with tritium service. This study assembles a test system to determine the flow characteristics for candidate alternate pumps. These tests are critical to themore » movement of tritium through the SHINE Tritium Purification System (TPS). The purpose of the pump testing is two-fold: (1) obtain baseline vacuum pump characteristics for an alternate (i.e. ''Normetex replacement'') pump intended for use in tritium service; and (2) verify that low pressure hydrogen gas can be transported over distances up to 300 feet by the candidate pumps. Flow rates and nominal system pressures have been identified for the SHINE Mo-99 production process Tritium Purification System (TPS). To minimize the line sizes for the transfer of low pressure tritium from the Neutron Driver Accelerator System (NDAS) to the primary processing systems in the TPS, a ''booster'' pump has been located near the accelerator in the design. A series of pump tests were performed at various configurations using hydrogen gas (no tritium) to ensure that this concept is practical and maintains adequate flow rates and required pressures. This report summarizes the results of the tests that have been performed using various pump configurations. The current design of the Tritium Purification System requires the ''booster'' pump to discharge to or to be backed by another vacuum pump. Since Normetex pumps are no longer manufactured, a commercially available Edwards scroll pump will be used to back the booster pump. In this case the ''booster pump'' is an Adixen Molecular Drag Pump (MDP 5011) and the backing pump is an Edwards (nXDS15iC) scroll pump. Various configurations of the two pumps and associated lengths of 3/4 inch tubing (0 feet to 300 feet) were used in combination with hydrogen and nitrogen flow rates ranging from 25-400 standard cubic centimeters per minute (sccm) to determine whether the proposed pump configuration meets the design criteria for SHINE. The results of this study indicate that even under the most severe conditions (300 feet of tubing and 400 sccm flow rate) the Adixen 5011 MDP can serve as a booster pump to transport gases from the accelerator (NDAS) to the TPS. The Target Gas Receiving System pump (Edwards nXDS15iC) located approximately 300 feet from the accelerator can effectively back the Adixen MDP. The molecular drag pump was able to maintain its full rotational speed even when the flow rate was 400 sccm hydrogen or nitrogen and 300 feet of tubing was installed between the drag pump and the Edwards scroll pump. In addition to maintaining adequate rotation, the pressure in the system was maintained below the target pressure of 30 torr for all flow rates, lengths of tubing, and process gases. This configuration is therefore adequate to meet the SHINE design requirements in terms of flow and pressure.« less
Shining light on the antenna chromophore in lanthanide based dyes.
Junker, Anne Kathrine R; Hill, Leila R; Thompson, Amber L; Faulkner, Stephen; Sørensen, Thomas Just
2018-04-03
Lanthanide based dyes and assays exploit the antenna effect, where a sensitiser-chromophore is used as a light harvesting antenna and subsequent excited state energy transfer populates the emitting lanthanide centred excited state. A rudimentary understanding of the design criteria for designing efficient dyes and assays based on the antenna effect is in place. By preparing kinetically inert lanthanide complexes based on the DO3A scaffold, we are able to study the excited state energy transfer from a 7-methoxy-coumarin antenna chromophore to europium(iii) and terbium(iii) centred excited states. By contrasting the photophysical properties of complexes of metal centres with and without accessible excited states, we are able to separate the contributions from the heavy atom effect, photoinduced electron transfer quenching, excited state energy transfer and molecular conformations. Furthermore, by studying the photophysical properties of the antenna chromophore, we can directly monitor the solution structure and are able to conclude that excited state energy transfer from the chromophore singlet state to the lanthanide centre does occur.
ERIC Educational Resources Information Center
Steinkamp, Erin
2016-01-01
Valley Park Middle School (VPMS) in Valley Park, MO, has the unique designation of being a not-so-secret gem in St. Louis County. The middle school shares its campus with the elementary and high school, creating opportunities to collaborate and work together to build a school district that not only shines academically, but also focuses on…
Paraprofessional of the Year 2007: Jackie Cornette
ERIC Educational Resources Information Center
Berry, John N., III
2007-01-01
Jackie Cornette is manager of the Western Branch of the Watauga County Library (WCL) in North Carolina. WCL is one of three county library systems that comprise the Appalachian Regional Library (ARL), headquartered in North Wilkesboro, North Carolina. According to Louise Humphrey, ARL director, Cornette has been a shining star in ARL since 1988.…
Studies Spotlight Charter Schools Aimed at Diversity
ERIC Educational Resources Information Center
Zubrzycki, Jaclyn
2012-01-01
Nearly six decades after "Brown" v. "Board of Education," the landmark U.S. Supreme Court decision that ushered in an era of efforts to integrate public schools, charter school advocates and researchers are shining a light on a number of those independent public schools that are integrated by design. Two new reports--one from…
Integrating the Curriculum: Faux Fall Repousse
ERIC Educational Resources Information Center
Kernan, Christine
2012-01-01
When introducing a new unit, art teachers know that sometimes a little "bling" can really grab students' attention. The author received "ooohs" and "aaahs" from her fourth-graders when they learned they would be creating "Faux Fall Repousse." The dazzling shine of the aluminum foil and the beautiful array of autumnal colors were impossible for…
Latecomers: The Sources and Impacts of Late Arrival among Adolescent Immigrant Students
ERIC Educational Resources Information Center
Allard, Elaine C.
2016-01-01
In this ethnographic study, the author describes and analyzes the experiences of latecomers, adolescent immigrant students who arrive late in the school year. She shines a light on the multifaceted challenges posed by these students' transnationalism, undocumented status, and labor migration, which contribute to their late arrival and threaten…
ERIC Educational Resources Information Center
Miranda, Maria Eugenia
2011-01-01
As the daughter of an interracial couple growing up in a middle-class town on Long Island in the 1970s, Soledad O'Brien learned not to let inappropriate or racist comments throw her. Now as the anchorwoman of CNN's "In America" documentary unit, she says she asks those uncomfortable questions about race all the time. She shines spotlight…
ERIC Educational Resources Information Center
Benanzer, Elizabeth; And Others
1991-01-01
Describes how local vocational schools and community colleges can play a key role in building a strong partnership between Japanese manufacturers and their U.S. workers. Kellogg Community College's (Michigan) partnership with Nippondenso and the Ohio Industrial Training Program's work with Honda of America are profiled. (JOW)
ERIC Educational Resources Information Center
Bussey, Thomas J.; Orgill, MaryKay
2015-01-01
Biochemistry instructors often use external representations--ranging from static diagrams to dynamic animations and from simplistic, stylized illustrations to more complex, realistic presentations--to help their students visualize abstract cellular and molecular processes, mechanisms, and components. However, relatively little is known about how…
Tag Team Tech: What Makes Google Tick.
ERIC Educational Resources Information Center
Janes, Joseph
2002-01-01
The Google search engine is growing in popularity and usually shines in performance ratings. This article summarizes findings from a technical paper written by Google's developers in 1998 before anyone had seen Google. Suggests that a careful reader of the paper will be rewarded with a deeper appreciation of the designers' ideas and…
Shining a Light on Electronics
ERIC Educational Resources Information Center
Statler, James D.
2009-01-01
While they produced a limited amount of light when first introduced, light-emitting diode (LED) lights offered the benefit of rarely burning out. As a result, they were initially used primarily as indicator lights. Advances in the technology have made available LEDs that produce far brighter light, and one application that has come to market is…
ERIC Educational Resources Information Center
Ragsdale, Adrienne
2011-01-01
Bright, shining gold, so daring and intense. Patterns reflecting the spirit of the portrait's subject, wisps of a look that intrigue the viewer. Something sultry in the eye, something shimmering on the lip... these are the works of Gustav Klimt. Klimt was Vienna's golden boy of painting. Through his use of pattern and the mosaic qualities in his…
The Dream World of Film: A Jungian Perspective on Cinematic Communication.
ERIC Educational Resources Information Center
Davies, Robert A.; And Others
1982-01-01
Explains the relevance to film criticism of Jung's theory of the collective unconscious and its archetypal manifestations. Analyzes "The Shining," a film representative of the presently dominant occult-horror genre, in terms of the Jungian approach. Discusses the role of film in relation to the world's psychic balance. (PD)
Neurophysiological Basis of Self-Regulation in Children and Youth
ERIC Educational Resources Information Center
Conway, Anne
2009-01-01
Many children and youth have difficulty controlling emotions and impulsive behavior. Brain science is shining new light on the process by which children develop self-regulation and controls from within. This article expands upon Fritz Redl and David Wineman's pioneering work aiding children in the development of flexible and effective controls…
Freedom as Non-Domination, Standards and the Negotiated Curriculum
ERIC Educational Resources Information Center
Hopkins, Neil
2015-01-01
This article investigates the application of Philip Pettit's concept of freedom as non-domination to the issues of educational standards and the negotiated curriculum. The article will argue that freedom as non-domination (and the connected concept of debating contestations as part of a legitimate democratic state) shines a critical light on…
Day users in wilderness: How different are they?
David N. Cole
2001-01-01
This study describes the trip and visitor characteristics, evaluations, and preferences of day users in wilderness, by contrasting them with overnight users. Data from the Three Sisters (OR), Desolation (CA), Bob Marshall (MT), Charles Deam (IN), Caney Creek (AR), Shining Rock (NC), and Cohutta (GA) Wildernesses are presented. Primary conclusions were that: (1) day...
ERIC Educational Resources Information Center
Klier, Gerhard
2012-01-01
With its park-like campus location overlooking the Hudson River and Catskills Mountains in New York's Hudson Valley, it's no wonder that Bard College is committed to being green. At the liberal arts college in Annandale-on-Hudson, students learn and live in 25 geothermal buildings on campus that don't burn fossil fuels on site. Instead of driving…
"Unhelpfully Complex and Exceedingly Opaque": Australia's School Funding System
ERIC Educational Resources Information Center
Dowling, Andrew
2008-01-01
Australia's system of school funding is notoriously complex and difficult to understand. This article shines some light on this issue by describing clearly the processes of school funding that currently exist in Australia. It describes the steps taken by federal and state governments to provide over $30 billion each year to government and…
76 FR 49201 - Endangered and Threatened Wildlife and Plants; Four Foreign Parrot Species
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-09
...). Its most closely related species are P. personata (G. R. Gray, 1848), masked shining parrot, which...). At that time, almost all Psittaciformes species (i.e., parrots) were included in Appendix II. CITES... conservation of this species occurring. Because there is no evidence of poaching (i.e., hunting by people to...
Destructive Leadership: The Hatfield and McCoy Feud
ERIC Educational Resources Information Center
Sparks, George; Wolf, Patricia; Zurick, Andryce M.
2015-01-01
This paper explores the phenomenon of destructive leadership using the historical case study of the feud between the Hatfields and McCoys. The characteristics of destructive leadership as well as the consequences of this leadership style are reviewed, examined and analyzed. Utilizing a case from history to shine light on a contemporary problem,…
'Rise 'n' Shine: Catholic Education and the African-American Community.
ERIC Educational Resources Information Center
Chineworth, Mary Alice, Ed.
African-Americans have been present in Catholic schools since their beginnings in the United States. The six essays in this book examine Catholic education from the perspective of the African-American Catholic. The essays underscore the continued challenge for continuing Catholic schools in the African-American community. They include: (1) an…
Steroids: To Test or to Educate?
ERIC Educational Resources Information Center
LaFee, Scott
2006-01-01
In February 2005, The Dallas Morning News published a multipart series on steroid use among high school students in Texas. The paper's four-month investigation was wide-ranging, but shined a particular spotlight upon alleged abuses in the 13,700-student Grapevine-Colleyville Independent School District, north of Dallas. Use of steroids and other…
What Matters, What Works: Advancing Achievement after School
ERIC Educational Resources Information Center
Public/Private Ventures, 2008
2008-01-01
This brief provides highlights from "Advancing Achievement: Findings from an Independent Evaluation of a Major After-School Initiative." The brief underscores the potential of after-school programs in the ongoing drive to advance children's academic achievement. It shines a light on some of the issues that matter most for programs striving to…
Postscript: Through TCM, STM Shines Bright
ERIC Educational Resources Information Center
Davelaar, Eddy J.; Usher, Marius; Haarmann, Henk J.; Goshen-Gottstein, Yonatan
2008-01-01
We find the reply by Kahana, Sederberg, and Howard helpful in clarifying the temporal-context model (TCM) function, in particular with regard to the elimination of the recency effect by a difficult distractor under parameters that still enable long-term contiguity effects to emerge. We agree with Kahana et al. that what matters most to the…
The Nature of Science: Integrating Historical, Philosophical, and Sociological Perspectives
ERIC Educational Resources Information Center
Espinoza, Fernando
2011-01-01
The role of science in society, along with its nature and development, are commonly misunderstood by students in the social sciences and humanities, and even those studying in the field. Fernando Espinoza shines light on these misconceptions to give readers a deeper understanding of science and its effect and influence upon society, through…
From Comfort Zone to Contact Zone Lessons from a Belfast Writing Centre
ERIC Educational Resources Information Center
Cain, Kathleen Shine
2011-01-01
American writing center director Kathleen Shine Cain analyzes the transformative experience of spending a year in a Belfast writing centre, resulting in a renewed appreciation of cross-national and cross-cultural partnerships. Although American writing center theory and pedagogy have informed the development of centers in Europe, Asia, and Africa,…
Storing Renewable Energy in Chemical Bonds
Helm, Monte; Bullock, Morris
2018-01-16
With nearly 7 billion people, the world's population is demanding more electricity every year. Improved technologies are bringing wind and solar power to our electrical grid. However, wind turbines and solar panels only work when the wind blows or the sun shines. PNNL scientists discuss catalysis approaches for storing and releasing energy on demand.
A Child's Garden of Books: Children's Literature Featured in Library Exhibition.
ERIC Educational Resources Information Center
Lamolinara, Guy
1998-01-01
Describes an exhibition at the Library of Congress called "From Sea to Shining Sea: An American Sampler" that contains a sampling of children's books that are representative of American life and show how children's literature has evolved over the centuries. Illustrations from several of the books are included. (LRW)
Excellence Gaps in Education: Expanding Opportunities for Talented Students
ERIC Educational Resources Information Center
Plucker, Jonathan A.; Peters, Scott J.
2016-01-01
In "Excellence Gaps in Education," Jonathan A. Plucker and Scott J. Peters shine a spotlight on "excellence gaps"--the achievement gaps among subgroups of students performing at the highest levels of achievement. Much of the focus of recent education reform has been on closing gaps in achievement between students from different…
It's Not about Me: Janet Crowther--Williamsburg Regional Library, VA
ERIC Educational Resources Information Center
Library Journal, 2004
2004-01-01
Janet Crowther was surprised to be considered a Mover & Shaker. As community partnership director for Williamsburg Regional Library (WRL), she has made a point of staying in the background so that the other stars--the librarians, the library, the community partners--can shine. "It's not about me," she says; it's about embedding the…
Misery Is Fun: Using Langston Hughes's "Black Misery."
ERIC Educational Resources Information Center
Benun, Ilise
1998-01-01
Uses "Black Misery," a picture book that shines a spotlight on 27 humiliating moments of childhood. Begins by reading the text and discussing the pictures and captions; then asks students to write a minimum of five captions in a manageable amount of time. Concludes by having students read their captions aloud and engage in more…
NASA Astrophysics Data System (ADS)
Rinaldi, Arlie J.; Lund, Paul E.; Blanco, Mario R.; Walter, Nils G.
2016-01-01
In response to intracellular signals in Gram-negative bacteria, translational riboswitches--commonly embedded in messenger RNAs (mRNAs)--regulate gene expression through inhibition of translation initiation. It is generally thought that this regulation originates from occlusion of the Shine-Dalgarno (SD) sequence upon ligand binding; however, little direct evidence exists. Here we develop Single Molecule Kinetic Analysis of RNA Transient Structure (SiM-KARTS) to investigate the ligand-dependent accessibility of the SD sequence of an mRNA hosting the 7-aminomethyl-7-deazaguanine (preQ1)-sensing riboswitch. Spike train analysis reveals that individual mRNA molecules alternate between two conformational states, distinguished by `bursts' of probe binding associated with increased SD sequence accessibility. Addition of preQ1 decreases the lifetime of the SD's high-accessibility (bursting) state and prolongs the time between bursts. In addition, ligand-jump experiments reveal imperfect riboswitching of single mRNA molecules. Such complex ligand sensing by individual mRNA molecules rationalizes the nuanced ligand response observed during bulk mRNA translation.
Mbuya, Mduduzi N N; Tavengwa, Naume V; Stoltzfus, Rebecca J; Curtis, Valerie; Pelto, Gretel H; Ntozini, Robert; Kambarami, Rukundo A; Fundira, Dadirai; Malaba, Thokozile R; Maunze, Diana; Morgan, Peter; Mangwadu, Goldberg; Humphrey, Jean H
2015-12-15
We sought to develop a water, sanitation, and hygiene (WASH) intervention to minimize fecal-oral transmission among children aged 0-18 months in the Sanitation Hygiene Infant Nutrition Efficacy (SHINE) trial. We undertook 4 phases of formative research, comprising in-depth interviews, focus group discussions, behavior trials, and a combination of observations and microbiological sampling methods. The resulting WASH intervention comprises material inputs and behavior change communication to promote stool disposal, handwashing with soap, water treatment, protected exploratory play, and hygienic infant feeding. Nurture and disgust were found to be key motivators, and are used as emotional triggers. The concept of a safe play space for young children was particularly novel, and families were eager to implement this after learning about the risks of unprotected exploratory play. An iterative process of formative research was essential to create a sequenced and integrated longitudinal intervention for a SHINE household as it expects (during pregnancy) and then cares for a new child. © The Author 2015. Published by Oxford University Press for the Infectious Diseases Society of America.
NASA Astrophysics Data System (ADS)
Coppi, B.
2012-03-01
Field and plasma configurations that can be the distinguishing feature of and surround ``shining'' black holes have been identified. Considering the observation of the Quasi Periodic Oscillations that can be associated with inhomogeneous rotating plasmas, tri-dimensional rotating configurations have been looked for and found under special conditions. One is that these configurations are radially localized, such as narrow plasma ring pairs. Another is that the rotation frequency is nearly constant over the rings. Only axisymmetric local configurations consisting of solitary plasma rings or periodic sequences of rings are found when the gradient of the rotation frequency is (locally) significant. Assuming that the plasma pressure is scalar the problem is reduced to the solution of two coupled non-linear differential equations. One, the ``Master Equation'' [1], relates the magnetic surface function to the plasma rotation frequency that is connected to the gravity field. The other, the Vertical Equilibrium Equation, relates the plasma pressure gradient to both the Lorentz force and to the plasma density profile through the gravitational force.[4pt] [1] B. Coppi, Phys. Plasmas 18, 032901 (2011).
Ntozini, Robert; Marks, Sara J; Mangwadu, Goldberg; Mbuya, Mduduzi N N; Gerema, Grace; Mutasa, Batsirai; Julian, Timothy R; Schwab, Kellogg J; Humphrey, Jean H; Zungu, Lindiwe I
2015-12-15
Access to water and sanitation are important determinants of behavioral responses to hygiene and sanitation interventions. We estimated cluster-specific water access and sanitation coverage to inform a constrained randomization technique in the SHINE trial. Technicians and engineers inspected all public access water sources to ascertain seasonality, function, and geospatial coordinates. Households and water sources were mapped using open-source geospatial software. The distance from each household to the nearest perennial, functional, protected water source was calculated, and for each cluster, the median distance and the proportion of households within <500 m and >1500 m of such a water source. Cluster-specific sanitation coverage was ascertained using a random sample of 13 households per cluster. These parameters were included as covariates in randomization to optimize balance in water and sanitation access across treatment arms at the start of the trial. The observed high variability between clusters in both parameters suggests that constraining on these factors was needed to reduce risk of bias. © The Author 2015. Published by Oxford University Press for the Infectious Diseases Society of America.
Claes, Julien M.; Dean, Mason N.; Nilsson, Dan-Eric; Hart, Nathan S.; Mallefet, Jérôme
2013-01-01
We report the discovery of light organs (photophores) adjacent to the dorsal defensive spines of a small deep-sea lanternshark (Etmopterus spinax). Using a visual modeling based on in vivo luminescence recordings we show that this unusual light display would be detectable by the shark's potential predators from several meters away. We also demonstrate that the luminescence from the spine-associated photophores (SAPs) can be seen through the mineralized spines, which are partially translucent. These results suggest that the SAPs function, either by mimicking the spines' shape or by shining through them, as a unique visual deterrent for predators. This conspicuous dorsal warning display is a surprising complement to the ventral luminous camouflage (counterillumination) of the shark. PMID:23425862
NASA Technical Reports Server (NTRS)
Kelch, W. L.; Linsky, J. L.
1978-01-01
Solar plages are modeled using observations of both the Ca II K and the Mg II h and k lines. A partial-redistribution approach is employed for calculating the line profiles on the basis of a grid of five model chromospheres. The computed integrated emission intensities for the five atmospheric models are compared with observations of six regions on the sun as well as with models of active-chromosphere stars. It is concluded that the basic plage model grid proposed by Shine and Linsky (1974) is still valid when the Mg II lines are included in the analysis and the Ca II and Mg II lines are analyzed using partial-redistribution diagnostics.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aduszkiewicz, A.; et al.
This paper presents several measurements of total production cross sections and total inelastic cross sections for the following reactions:more » $$\\pi^{+}$$+C, $$\\pi^{+}$$+Al, $$K^{+}$$+C, $$K^{+}$$+Al at 60 GeV/c, $$\\pi^{+}$$+C and $$\\pi^{+}$$+Al at 31 GeV/c . The measurements were made using the NA61/SHINE spectrometer at the CERN SPS. Comparisons with previous measurements are given and good agreement is seen. These interaction cross sections measurements are a key ingredient for neutrino flux prediction from the reinteractions of secondary hadrons in current and future accelerator-based long-baseline neutrino experiments.« less
Information Conservation is Fundamental: Recovering the Lost Information in Hawking Radiation
NASA Astrophysics Data System (ADS)
Zhang, Baocheng; Cai, Qing-Yu; Zhan, Ming-Sheng; You, Li
2013-06-01
In both classical and quantum world, information cannot appear or disappear. This fundamental principle, however, is questioned for a black hole, by the acclaimed "information loss paradox." Based on the conservation laws of energy, charge, and angular momentum, we recently show the total information encoded in the correlations among Hawking radiations equals exactly to the same amount previously considered lost, assuming the nonthermal spectrum of Parikh and Wilczek. Thus the information loss paradox can be falsified through experiments by detecting correlations, for instance, through measuring the covariances of Hawking radiations from black holes, such as the manmade ones speculated to appear in LHC experiments. The affirmation of information conservation in Hawking radiation will shine new light on the unification of gravity with quantum mechanics.
Claes, Julien M; Dean, Mason N; Nilsson, Dan-Eric; Hart, Nathan S; Mallefet, Jérôme
2013-01-01
We report the discovery of light organs (photophores) adjacent to the dorsal defensive spines of a small deep-sea lanternshark (Etmopterus spinax). Using a visual modeling based on in vivo luminescence recordings we show that this unusual light display would be detectable by the shark's potential predators from several meters away. We also demonstrate that the luminescence from the spine-associated photophores (SAPs) can be seen through the mineralized spines, which are partially translucent. These results suggest that the SAPs function, either by mimicking the spines' shape or by shining through them, as a unique visual deterrent for predators. This conspicuous dorsal warning display is a surprising complement to the ventral luminous camouflage (counterillumination) of the shark.
Bartke, Rebecca M; Cameron, Elizabeth L; Cristie-David, Ajitha S; Custer, Thomas C; Denies, Maxwell S; Daher, May; Dhakal, Soma; Ghosh, Soumi; Heinicke, Laurie A; Hoff, J Damon; Hou, Qian; Kahlscheuer, Matthew L; Karslake, Joshua; Krieger, Adam G; Li, Jieming; Li, Xiang; Lund, Paul E; Vo, Nguyen N; Park, Jun; Pitchiaya, Sethuramasundaram; Rai, Victoria; Smith, David J; Suddala, Krishna C; Wang, Jiarui; Widom, Julia R; Walter, Nils G
2015-05-01
Four days after the announcement of the 2014 Nobel Prize in Chemistry for "the development of super-resolved fluorescence microscopy" based on single molecule detection, the Single Molecule Analysis in Real-Time (SMART) Center at the University of Michigan hosted a "Principles of Single Molecule Techniques 2014" course. Through a combination of plenary lectures and an Open House at the SMART Center, the course took a snapshot of a technology with an especially broad and rapidly expanding range of applications in the biomedical and materials sciences. Highlighting the continued rapid emergence of technical and scientific advances, the course underscored just how brightly the future of the single molecule field shines. © 2014 Wiley Periodicals, Inc.
2012-06-13
ISS031-E-116058 (13 June 2012) --- Polar mesospheric clouds in the Northern Hemisphere are featured in this image photographed by an Expedition 31 crew member on the International Space Station. In both the Northern and Southern Hemisphere, during their respective late spring and early summer seasons, polar mesospheric clouds are at the peak of their visibility. Visible from the ground during twilight, aircraft in flight, and the International Space Station, they typically appear as delicate shining threads against the darkness of space?hence their other name of noctilucent or ?night-shining? clouds. On the same day this image was taken from the space station while it was passing over the night-darkened Tibetan Plateau, polar mesospheric clouds were also visible to aircraft flying above Canada. In addition to this still image, the space station crew took a time-lapse image sequence of polar mesospheric clouds several days earlier (June 5, 2012) while passing over western Asia; this is first such sequence of images of the phenomena taken from orbit. Polar mesospheric clouds form between 76-85 kilometers above the Earth?s surface, when there is sufficient water vapor at these high altitudes to freeze into ice crystals. The clouds are illuminated by the setting sun while the ground surface below is in darkness, lending them their night-shining properties. In addition to the illuminated tracery of polar mesospheric clouds trending across the center of the image, lower layers of the atmosphere are also illuminated; the lowest layer of the atmosphere, the stratosphere, is indicated by dim orange and red tones. While the exact cause of formation of polar mesospheric clouds is still debated?dust from meteors, global warming, and rocket exhaust have all been suggested as contributing factors?recent research suggests that changes in atmospheric gas composition or temperature has caused the clouds to become brighter over time.
Opto-mechanical design of vacuum laser resonator for the OSQAR experiment
NASA Astrophysics Data System (ADS)
Hošek, Jan; Macúchová, Karolina; Nemcová, Šárka; Kunc, Štěpán.; Šulc, Miroslav
2015-01-01
This paper gives short overview of laser-based experiment OSQAR at CERN which is focused on search of axions and axion-like particles. The OSQAR experiment uses two experimental methods for axion search - measurement of the ultra-fine vacuum magnetic birefringence and a method based on the "Light shining through the wall" experiment. Because both experimental methods have reached its attainable limits of sensitivity we have focused on designing a vacuum laser resonator. The resonator will increase the number of convertible photons and their endurance time within the magnetic field. This paper presents an opto-mechanical design of a two component transportable vacuum laser resonator. Developed optical resonator mechanical design allows to be used as a 0.8 meter long prototype laser resonator for laboratory testing and after transportation and replacement of the mirrors it can be mounted on the LHC magnet in CERN to form a 20 meter long vacuum laser resonator.
Windass, J D; Newton, C R; De Maeyer-Guignard, J; Moore, V E; Markham, A F; Edge, M D
1982-01-01
An 82 base pair DNA fragment has been synthesised which contains the E. coli trp promoter and operator sequences and also encodes the first Shine Dalgarno sequence of the trp operon. This DNA fragment is flanked by EcoRI and ClaI/TaqI cohesive ends and is thus easy to clone, transfer between vector systems and couple to genes to drive their expression. It has been cloned into plasmid pAT153, producing a convenient trp promoter vector. We have also joined the fragment to a synthetic IFN-alpha 1 gene, using synthetic oligonucleotides to generate a completely natural, highly efficient bacterial translation initiation signal on the promoter proximal side of the IFN gene. Plasmids carrying this construction enable E. coli cells to express IFN-alpha 1 almost constitutively and with significantly higher efficiency than from a lacUV5 promoter based system. Images PMID:6184675
Migrating to the City: Negotiating Gender and Race in Marie Arana's "Lima Nights"
ERIC Educational Resources Information Center
Heredia, Juanita
2016-01-01
This article examines Peruvian-American Marie Arana's second novel "Lima Nights" (2008) in which she represents Amazonian indigenous migrations to Lima, Peru during and after the Shining Path civil war years (1986-2006). As part of a generation of transnational US Latina authors in the post-2000 period, Arana recovers the image of the…
Middle Level Leadership... and All That Jazz!
ERIC Educational Resources Information Center
Kinney, Patti; Tomlin, Dru
2013-01-01
Much like a Jazz group, successful middle level schools are also founded on elements of improvisation, collaboration, teamwork, and responsive communication. Just as the director of the jazz group must have a solid foundation of music theory, the skills to bring out the best in the players, and an attitude that allows others to shine, those who…
Objects Take Center Stage in History Books
ERIC Educational Resources Information Center
Zarnowski, Myra
2006-01-01
Most history books for children focus on people, places, and events. In a different approach, some authors focus on an object--an everyday item that might be ignored when it comes to writing history. They shine a spotlight on the item, and in the process, they add insight and interest to human history. This article looks at four outstanding books…
The Quiet Crisis: The Impact of the Economic Downturn on the Nonprofit Sector
ERIC Educational Resources Information Center
Bridgeland, John M.; McNaught, Mary; Reed, Bruce; Dunkelman, Marc
2009-01-01
This report was written to shine a spotlight on the under-reported plight of America's nonprofit organizations and to make recommendations for how the nation can respond. In the wake of the economic downturn, hospitals, nursing homes, nursery schools, senior centers, soup kitchens, and other nonprofit organizations have been hit by a triple…
ERIC Educational Resources Information Center
Guerrero, Lourdes R.
2009-01-01
This qualitative research study focused on the eight bilingual, content area high school teachers implementing Project SOL (Secondary Online Learning) in Southern California during the 2008-2009 school year. It documents their effort to integrate an online curriculum from the "Colegio de Bachilleres" in Mexico obtained through the UCLA…
10 Ways to...Decorate Your Classroom
ERIC Educational Resources Information Center
Prescott, Jennifer
2005-01-01
Recruit the best decorating corps you have for this year's classroom makeover--your students! Not only does involving kids save money and effort on your part, teachers agree that it increases kids' sense of involvement and respect. In this article, the author presents 10 teacher-tested ideas for a classroom that shines with color and learning: (1)…
New Report Shines Light on Installed Costs and Deployment Barriers for
Laboratory (NREL) are making available the most detailed component and system-level cost breakdowns to date previously unknown soft costs for the first time. The report, titled "Installed Cost Benchmarks and interest in pairing distributed PV with storage, but there's a lack of publicly available cost data and
Shining a Light on Alport Syndrome.
Hale, Lorna J; Little, Melissa H
2018-05-17
In this issue of Cell Chemical Biology, Omachi et al. (2018) present a split Nanoluciferase system to identify successful protein trimerization in Alport syndrome. This elegant proof of concept suggests opportunities for drug screening for Alport syndrome and may be transferable to the study of other diseases affecting protein-protein interactions. Copyright © 2018 Elsevier Ltd. All rights reserved.
Paddle Your Own Canoe: Metaphors for Teaching between the Tides
ERIC Educational Resources Information Center
Wright, W. Alan; Monette, Marie-Jeanne; Hamilton, Beverley
2010-01-01
Nearly twenty college and university voyageurs hailing from Atlantic Canada to the Pacific Coast and points in between, as well as intrepid pedagogues from institutions of higher education from Asia and Australia rendezvous at the Small Craft Aquatic Centre in Fredericton, New Brunswick, on the shores of the St. John River. The sun shines brightly…
ERIC Educational Resources Information Center
Scott, Beverly
2005-01-01
Deep down in the depths of the sea, beautiful fish, mysterious ocean life, and unusual plants glimmer and glow in the eerie atmosphere of an ever-changing ocean. This article describes how, with this vision and a purpose in mind, three teachers pulled open classroom walls and joined forces so their second graders could create a mammoth 30 x 75"…
A Practical Guide for Day Care Personnel: Let the Sun Shine In.
ERIC Educational Resources Information Center
DeLorey, John L., Jr.; Cahn, Marjorie E.
This handbook of practical guidelines for daily life in day care is addressed to caregivers, teachers, directors, and students who want to provide high quality care for children. Separate sections are devoted to (1) day care as a daily living experience; (2) the parent-caregiver relationship; (3) priorities for health and safety, staff…
Shining Light into Cosmic Dark Ages
NASA Astrophysics Data System (ADS)
Fialkov, Anastasia
2018-06-01
Exploration of the early Universe is ongoing. One of the most interesting probes of the epoch is the redshifted 21-cm line of neutral hydrogen. Modeling of this signal is difficult due to large uncertainties in both astrophysical and cosmological parameters that describe the high redshift Universe. In my talk I will discuss current theoretical understanding and the status of modeling.
ERIC Educational Resources Information Center
Leimbach, Michael P.
2005-01-01
Outsourcing in the training and development industry has been steadily increasing and shows no indication of slowing (Surgue & Kim, 2004). Gainey and Klaas's study shines light on the role of interfirm trust in effective outsourcing relationships. This reaction addresses a methodological question of the effect of the rating target on the results,…
From Sea to Shining Sea, A Report on the American Environment--Our Natural Heritage.
ERIC Educational Resources Information Center
President's Council on Recreation and Natural Beauty, Washington, DC.
This report presents a limited cross-section of environmental problems and of the actions beginning to be taken to cope with these problems. Its objectives are to: (1) outline progress in environmental improvement programs since the 1965 White House Conference on Natural Beauty, (2) present proposals and recommendations which will stimulate…
Plateaus, Dips, and Leaps: Where to Look for Inventions and Discoveries during Skilled Performance
ERIC Educational Resources Information Center
Gray, Wayne D.; Lindstedt, John K.
2017-01-01
The framework of "plateaus, dips, and leaps" shines light on periods when individuals may be inventing new methods of skilled performance. We begin with a review of the role "performance plateaus" have played in (a) experimental psychology, (b) human-computer interaction, and (c) cognitive science. We then reanalyze two classic…
ERIC Educational Resources Information Center
Hurowitz, Amanda
2010-01-01
Sometimes students come up with crazy ideas. When this author first started teaching at Thomas Jefferson High School for Science and Technology in Virginia five years ago, she had a sophomore share such an idea with her. He wanted to put solar panels on the school's roof as a way to reduce the school's carbon footprint and set a bright clean…
Using LAMP Applications to Make Our Library Shine
ERIC Educational Resources Information Center
White, Andrew; Balsamo, Joseph
2005-01-01
There has been a move afoot in libraries of all kinds to incorporate open source software and applications to better support their rapidly evolving information access and delivery services. There has been particular interest in a specific configuration of open source components?known by the acronym LAMP?that can be used to build fairly complex Web…
Flipping Out over Online Library Instruction: A Case Study in Faculty-Librarian Collaboration
ERIC Educational Resources Information Center
Hawes, Sandra Lee; Mason Adamson, Jane
2016-01-01
This case study both shines a light on the flipped classroom paradigm and exemplifies successful faculty-librarian collaboration. The co-authors leveraged an existing collegial relationship into a productive partnership to create a multi-faceted flipped classroom module. The module, developed over the course of three and a half years, was designed…
What Happens When a Teacher Uses Metalanguage to Teach Spelling?
ERIC Educational Resources Information Center
Daffern, Tessa
2017-01-01
While learning to spell in English is integral to becoming a literate writer, it is a complex and gradual skill to master. If English spelling is understood from a phonological, orthographic, and morphological perspective, its transparency becomes evident. The case study described in this article shines a light on an Australian Year 4 classroom…
K.F Connor
2004-01-01
Shining sumac is an upright, deciduous, clonal shrub or (rarely) small tree from 3 to 6 m tall. Bark ranges in color from light brown to gray to reddish-brown. Shoots and twigs are hairy and reddish in color. Twigs have conspicuous lenticels. The sparsely branched, flat crown is composed of alternate, pinnately compound leaves approximately 15 to 30 cm long, with wings...
Teachers Are the Center of Education: Writing, Learning and Leading in the Digital Age
ERIC Educational Resources Information Center
National Writing Project (NJ1), 2010
2010-01-01
This series of reports, "Teachers Are the Center of Education," was developed to highlight the importance of teachers and the quality of their work. This specific report, a partnership among the College Board, the National Writing Project and Phi Delta Kappa International, shines the spotlight on one aspect of teacher work: the…
Shining Lights or Lone Wolves? Creativity and Self Image in Primary School Children.
ERIC Educational Resources Information Center
Hoff, Eva V.; Carlsson, Ingegerd
2002-01-01
This study examined the relationship between self-image and creativity in 69 Swedish 4th graders using three measures of creativity. Results showed no self-image differences between children with high and low creativity. Different creativity measures were significantly related with the exception of one subtest of the Creative Functioning Test,…
The Complex Case of Fear and Safe Space
ERIC Educational Resources Information Center
Stengel, Barbara S.
2010-01-01
Here I shine light on the concept of and call for safe space and on the implicit argument that seems to undergird both the concept and the call, complicating and problematizing the taken for granted view of this issue with the goal of revealing a more complex dynamic worthy of interpretive attention when determining educational response. I…
ERIC Educational Resources Information Center
Demski, Jennifer
2011-01-01
American higher education is suffering from a dropout pandemic. About 30% of freshmen at four-year colleges don't return for their sophomore year, according to a 2010 report by the American Institutes for Research. Such a high failure rate threatens to make a mockery of President Obama's goal for the US to have the highest proportion of college…
Predators: Uncomfortable Truths about Campus Rapists
ERIC Educational Resources Information Center
Lisak, David
2004-01-01
In this article, the author cites a few studies which revealed startling statistics about sexual violence in colleges, particularly rape. He notes that sexual violence remains as much a dirty secret on the campuses as it is in the larger society. It flourishes because to confront it, an institution must be willing to shine a bright light on…
Code of Federal Regulations, 2010 CFR
2010-01-01
...: CERTIFICATION AND OPERATIONS CERTIFICATION AND OPERATIONS: AIRPLANES HAVING A SEATING CAPACITY OF 20 OR MORE... must be kept low and shielded against shining into the airplane's windows or doors. (2) The airplane... the ground to protect participants. No other equipment that is not part of the airplane's emergency...
Shining a Spotlight on the Defense Acquisition Workforce -- Again
2009-01-01
Defense AT&L, January–February, 2008. Rostker, Bernard , A Call to Revitalize the Engines of Government, Santa Mon- ica, CA: RAND Corporation, OP-240...there are a large number of individuals in the 1101 series who are part of the AW, (3,816 in FY 2007), but they 13 Note that some FAI analyses have
In the Red Shadow of the Earth
ERIC Educational Resources Information Center
Hughes, Stephen W.; Hosokawa, Kazuyuki; Carroll, Joshua; Sawell, David; Wilson, Colin
2015-01-01
A technique is described for calculating the brightness of the atmosphere of the Earth that shines into the Earth's umbra during a total lunar eclipse making the Moon red. This "Rim of Fire" is due to refracted unscattered light from all the sunrises and sunsets rimming the Earth. In this article, a photograph of the totally eclipsed…
The Neoliberal Food Regime: Neoregulation and the New Division of Labor in North America
ERIC Educational Resources Information Center
Pechlaner, Gabriela; Otero, Gerardo
2010-01-01
We undertake a comparative investigation of how neoliberal restructuring characterizes the third food regime in the three North American countries. By contrasting the experience of the two developed countries of the United States and Canada with that of the developing country of Mexico, we shine some empirical light on the differential impact of…
ERIC Educational Resources Information Center
Lyons, Sandra; Winje, Carolyn
2007-01-01
Collaboration and coordination among providers of social and health services have long been prescribed for remedying fragmented service systems and achieving integrated services. Yet ambitious efforts to achieve these goals have often been disappointing. This three-year study examined the Family and Community Partnership (FCP) in Palm Beach…
Shining Stars: Public Library Service to Children in Shelters.
ERIC Educational Resources Information Center
Carlson, Pam
1992-01-01
The Orange County Public Library (CA) sponsors programing at the Orangewood Children's Home, a shelter for abused and neglected children. Programs include giving each child a book to keep and a library card, story times, and special programing. The library system now operates a branch at the home, and the librarian's position is being continued.…
Automatic visual inspection system for microelectronics
NASA Technical Reports Server (NTRS)
Micka, E. Z. (Inventor)
1975-01-01
A system for automatically inspecting an integrated circuit was developed. A device for shining a scanning narrow light beam at an integrated circuit to be inspected and another light beam at an accepted integrated circuit was included. A pair of photodetectors that receive light reflected from these integrated circuits, and a comparing system compares the outputs of the photodetectors.
Am I Safe Here? LGBTQ Teens and Bullying in Schools
ERIC Educational Resources Information Center
Short, Donn
2017-01-01
"Am I safe here?" LGBTQ students ask this question every day within the school system. This book shines a light on the marginalization and bullying faced by LGBTQ youth, offering a new conceptualization of school safety. Donn Short treats students as the experts on what happens in their schools, giving them a chance to speak for…
Crisis Communication and Management: Surviving a Public Relations Crisis
ERIC Educational Resources Information Center
Eramo, Eric M.
2009-01-01
Crisis management, or crisis communication, is never a good thing for a business to experience. It is, however, a public relations' professional moment to shine and put their honed skills to good use. A good crisis management plan is not only action during the crisis but preparation and reflection. Hiring a PR firm that deals with crisis…
Impact of changing wax type during storage on mandarin flavor and quality attributes
USDA-ARS?s Scientific Manuscript database
Mandarin (Citrus reticulata Blanco) packers sometimes apply a storage wax (SW) designed to limit water loss during the initial part of storage and then replace it with a higher shine pack wax (PW) prior to shipment of the fruit. Mandarins are prone to the development of off-flavors as a result of lo...
The Gift of Writing: An Interview with Janet Allen
ERIC Educational Resources Information Center
Lesesne, Teri S.
2005-01-01
Janet Allen cares passionately about books and reading and that passion shines in her presentation. When she had her first foray into children's literature, it was expected that she would have a great deal to say to educators about writing and reading. In this article, an interview with the author is presented. Allen talks about how her experience…
Implications for Math and Science Instruction from the TIMSS 1999 Video Study
ERIC Educational Resources Information Center
Roth, Kathleen; Givvin, Karen B.
2008-01-01
Media headlines often announce that U.S. students do not shine in international comparisons in mathematics and science, but seldom does any one focus on the specifics of how instruction differs among countries and how U.S. educators can alter their practices to improve student achievement. Examining key findings from the Third International…
Crossing the Divide: Helen Keller and Yvonne Pitrois Dialogue on Diversity
ERIC Educational Resources Information Center
Hartig, Rachel
2007-01-01
How do those who are living with a difference most effectively cross the cultural divide and explain themselves to mainstream society? This is a central question raised by Yvonne Pitrois in her biography of Helen Keller, titled "Une nuit rayonnante: Helen Keller" [A Shining Night: Helen Keller]. Helen Keller responded to Pitrois' book in a…
Shining Light on Social Learning Circuits.
Chang, Steve W C; Dal Monte, Olga
2018-05-28
Learning from others powerfully shapes our lives, yet the circuit-specific mechanisms underlying social learning in the brain remain unclear. A recent study in mice provides evidence that direct neuronal projections from the anterior cingulate cortex (ACC) to the basolateral amygdala (BLA) play a critical role in observational fear learning. Copyright © 2018 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Bravar, Alessandro
2010-03-01
As the intensity of neutrino beams produced at accelerators increases, the systematic errors due to the poor characterization of the neutrino flux become a limiting factor for high precision neutrino oscillation experiments like T2K. This limitation comes mainly from the poor knowledge of production cross sections for pions and kaons at the same energy and over the same phase-space yielding these neutrino beams. Therefore new hadro-production measurements are mandatory. The NA61/SHINE is a large acceptance hadron spectrometer at the CERN-SPS designed for the study of the hadronic final states produced in interactions of various beam particles (protons, π's, and heavy ions) with a variety of fixed targets at the SPS energies. Ongoing measurements with the NA61 detector for characterizing the neutrino beam of the T2K experiment at J-PARC are introduced. These measurements are performed using a 30 GeV proton beam impinging on carbon targets of different lengths, including a replica of the T2K target. The performance of the NA61 detector and preliminary NA61 measurements from the 2007 run are presented.
2017-12-08
In this rare image taken on 19 July, the wide-angle camera on the international Cassini spacecraft has captured Saturn’s rings and our planet Earth and Moon in the same frame. The dark side of Saturn, its bright limb, the main rings, the F ring, and the G and E rings are clearly seen; the limb of Saturn and the F ring are overexposed. The ‘breaks’ in the brightness of Saturn’s limb are due to the shadows of the rings on the globe of Saturn, preventing sunlight from shining through the atmosphere in those regions. The E and G rings have been brightened for better visibility. Earth, 1.44 billion km away in this image, appears as a blue dot at centre right; the Moon can be seen as a fainter protrusion off its right side. The other bright dots nearby are stars. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Empowering aged care nurses to deliver person-centred care: Enabling nurses to shine.
Marriott-Statham, Kelly; Mackay, Maria; Brennan, Ngaire; Mackay, Jacinta
2018-05-23
In this paper, the authors will describe the journey of registered nurses across a series of workshops as part of a research project that was undertaken in a regional aged care service in New South Wales, Australia. The aim of the project was to empower the participant registered nurses to positively influence the health care workplace culture within the residential care home by raising consciousness about their own practice. Registered nurses were actively involved in this reconnaissance phase of a participatory action research project through practice development principles and methods. Registered nurses determined the content and the outcomes of the overall program. The researchers evaluated the impact of a series of workshops, designed to develop skills and knowledge using nominal group technique. Results revealed registered nurses perceived they were empowered to flourish, and developed an understanding of the uniqueness of their role. A shared understanding of the role of the registered nurse in the aged care setting was fundamental in enabling them to feel empowered to lead their team and contribute positively to the workplace culture. Overall, the outcomes of this project have positively impacted workplace culture. Copyright © 2018. Published by Elsevier Ltd.
Human Performance in Extreme Environments
NASA Technical Reports Server (NTRS)
Williams, Sunita; Fiedler, Edna R.; Harrison, Albert A.
2008-01-01
Even on a bad day, looking down from orbit is a powerful and enjoyable experience, enhanced by the knowledge that time in orbit represents only a tiny fraction of one's life. You look down at Earth and you feel a sense of peace and solidarity. You look at the stars, and because they are not obscured by atmosphere, they are far more abundant than you realized, and they shine very bright. Later on you will reflect on this as one of life's greatest moments. Today astronauts and a few wealthy space tourists have been able to experience staying on the International Space Station. As representatives of humankind in space, astronauts have to get out there and tell people what it's like, and to encourage successive generations of children to consider careers in space. Perhaps the more people who can experience this view, the nicer we will all be to one another. Astronauts must speak authoritatively, without arrogance or a lack of humility. Each astronaut is an emissary who can share his or her experiences and educate people who will not have the opportunity to fly in space. This chapter is a part of that communication process.
IR spectra of Saturn's ring spokes and multiple shines in the Saturn-rings system
NASA Astrophysics Data System (ADS)
D'Aversa, Emiliano; Bellucci, Giancarlo; Filacchione, Gianrico; Cerroni, Priscilla; Nicholson, Phil D.; Carrozzo, Filippo G.; Altieri, Francesca; Oliva, Fabrizio; Geminale, Anna; Sindoni, Giuseppe; Hedman, Matthew M.
2017-04-01
During the last Saturn equinox, in 2009 August, spokes on the Saturn's B ring have been observed for the first time spectroscopically, at visible and infrared wavelengths. Measurements were obtained by Cassini-VIMS (Visual and Infrared Mapping Spectrometer) instrument in the 0.35-5.1 micron range. Spokes are either dark or bright features appearing on the B ring straddling the equinoxes, round to elongated in shape, lasting for minutes to hours, and moving partially pushed by Saturn's magnetic field. Previous spokes observations date back to the Voyager (1980 equinox,[1]), followed by a HST campaign (1995 equinox,[2]), and more recently Cassini-ISS images (2009 equinox,[3]). Theoretical models of spoke formation and evolution have been developed based on those observations, but there is not unanimous consensus on them. The most spread model considers the spoke as a cloud of very fine particles electrostatically levitating from the regolith of ring's boulders, and hovering on the ring plane while interacting with the ambient plasma until complete charge neutralization. The process triggering the grain charging is not yet clear (meteoroid bombardment, impacts of Saturn's lightnings electrons, etc.) but in any case a very small grain mass (high charge-to-mass ratio) is needed to allow electrostatic repulsion. From the observational point of view, small grain sizes (0.3-0.5 micron) have been retrieved by modeling the spoke reflectance in the visible spectral range (both Voyager, HST, and Cassini were equipped with multispectral imaging cameras). However, a first VIMS spoke observation ([4]) inferred a more spread size distribution (0.3 to 2.5 microns) to explain the high spoke contrast measured in the infrared. Here we will report about an analysis of two selected sets of spokes observed by VIMS. This selection aimed to include both high and low phase angle observations, and to take advantage from the highest spatial resolution data achieved in the infrared. We will highlight the importance of including illumination sources other than the Sun in the radiative transfer analysis, namely the Saturn-shine and the ring-shine. Their effect, more evident in the infrared range thanks to the deep water ice and methane bands, may bias the retrieval of spoke's micro-physics depending on the overall geometry of the scene. Possible debiasing and evaluation of consequences for visible retrievals will be illustrated. Acknowledgments - This work has been supported by Italian Space Agency (ASI) through Cassini contract. References - [1] Smith et al.,1981,Science,212,163. [2] McGhee et al.,2005,Icarus,173,508. [3] Mitchell et al.,2013,Icarus,225,446. [4] D'Aversa et al.,2010,Geoph.Res.Lett.,37,GL041427.
Dusty Relic to Shining Treasure: Embedded in a Multicultural Environment
ERIC Educational Resources Information Center
Avery, Beth Fuseler; Batman, Cindy
2014-01-01
Far from being dusty old relics who are guardians of the book, embedded librarians need to be proactively leading students through the digital maze of the virtual library. Working with students more than 7,000 miles away changed perceptions of how to teach and learn, and how people interact online. We will share how as embedded librarians we…
Growing Pains: Scaling up the Nation's Best Charter Schools. Education Sector Reports
ERIC Educational Resources Information Center
Education Sector, 2009
2009-01-01
Amistad Academy is a bright shining star in public school reform. Founded in 1999 in a renovated warehouse in a blighted New Haven, Connecticut, neighborhood by a group of Yale law school students, the 289-student charter school has won the praise of the last two federal education secretaries. Educators throughout the country have traveled to the…
ERIC Educational Resources Information Center
Hall, McClellan
The National Indian Youth Leadership (NIYL) model was created to develop leadership skills for Indian youth to perform their future roles in the family, school, tribe, and nation. The model not only instills leadership skills and values through hands-on learning opportunities, but also challenges youth to apply those skills through projects they…
ShopGirls Shine in Eco-Marathon
ERIC Educational Resources Information Center
Stowell, Shante
2011-01-01
The ShopGirls of Granite Falls (WA) High School are the first-ever all-female team to successfully design, build, and race a prototype diesel car in the Shell Eco-marathon. The team took first place in the diesel fuel-efficiency category with a vehicle that achieved 470 miles per gallon! The idea for the ShopGirls came when Vervia Gabriel, career…
Rise and shine: How do northwest trees know when winter is over?
Andrea Watts; Connie Harrington; Peter Gould
2016-01-01
Trees bursting forth with new leaves signal the arrival of spring. Budburst for most temperate tree species occurs after a tree has been exposed to a sufficient number of chilling and forcing hours over the winter. Waiting until these chilling and forcing hours have accumulated is a survival mechanism. If a tree bursts bud prematurely, delicate tissue may...
New York City's Smaller Schools Movement: Bronx Lab School, New York City Public Schools
ERIC Educational Resources Information Center
Schachter, Ron
2009-01-01
This article profiles the 5-year-old Bronx Lab School, a shining achievement in Chancellor Joel Klein's aggressive program of creating new, small schools, almost 400 of which have opened over the past seven years. It's unprecedented anywhere in America. Bronx Lab--which shares the building with similarly sized schools focused on areas such as…
Shining the Light: A Report Card on Georgia's System of Public Higher Education
ERIC Educational Resources Information Center
Palmiero, Phyllis
2008-01-01
Parents and taxpayers are frustrated by reports of students who have failed to master the reading, writing, and thinking skills they expect of college graduates. They are searching for evidence of how much or how little students learn at competing institutions. And they are wondering why a third of full-time college graduates don't finish a…
"A Nation at Risk" and No Child Left Behind: Deja Vu for Administrators?
ERIC Educational Resources Information Center
Hunt, John W.
2008-01-01
When the National Commission on Excellence in Education submitted "A Nation at Risk" to Secretary of Education Terrel Bell on 26 April 1983, there was little to suggest that this report would shine a spotlight on education that would last a quarter of a century. Indeed, not long after the release of this document, critics were already…
NREL Develops Switchable Solar Window | News | NREL
electricity at a high efficiency have been developed by scientists at the U.S. Department of Energy's National reversibly absorbed into the device. When solar energy heats up the device, the molecules are driven out, and the device is darkened. When the sun is not shining, the device is cooled back down, and the molecules
"The Cracks Are Where the Light Shines in": Grief in the Classroom
ERIC Educational Resources Information Center
Granek, Leeat
2009-01-01
The death of the author's mother was not a surprise. Despite eighteen years of relative psychological and physical health while she lived with metastatic breast cancer, the last year of her life was a violent struggle against the disease that aggressively invaded her body. Her mother fought her death until the last moment. Within five days of…
Catching the Spark: Student Activism and Student Data as a Catalyst for Systemic Transformation
ERIC Educational Resources Information Center
Bragg, Debra; McCambly, Heather; Durham, Brian
2016-01-01
The newest student activist movement appears to be amplifying what some higher education practitioners have talked about for a long time: students of color have been granted access to an educational opportunity that was not as advertised, and the result is not good enough. Others are shining the spotlight on race, class, identity, and equity as…
Skill and Physical Activity: A Central Dogma for Kinesiology
ERIC Educational Resources Information Center
Zelaznik, Howard N.; Harper, William A.
2007-01-01
Kinesiology has a long and storied tradition and history. The growth of our discipline and what might be called our subdisciplines has been the shining achievement of the 1970-2006 era, spurred on by Henry's (1964) call for an academic discipline. In this short thought paper, we argue that we have lost sight of the discipline in a quest to become…
Diversity and Challenge in Teacher Education. Papers from the Illinois/Indiana ATE Mini-Clinic.
ERIC Educational Resources Information Center
Clay-Mendez, Luis Felipe, Ed.
The document presents the following papers: (1) "Eliot Wigginton: A "Shining Moment" of the Mini Clinic" (Luis Felipe Clay Mendez); (2) "Telling it Like it Is: Attitudes and Opinions of Beginning Teachers" (Erma Williams and others); (3) "Redesigning the Role of the Student Teacher Supervisor: Use of Reflective Techniques" (Barbara S. De Salvo);…
ERIC Educational Resources Information Center
Candal, Cara Stillings
2016-01-01
Recent studies continue to shine light on high-performing charter schools. While Boston-area charter schools--a concentrated group of high-performers--garner more attention than others, many excellent schools outside of Boston have been quietly chipping away at the achievement gap between advantaged and disadvantaged students. One of these schools…
Investigation of the effect of AtWIN1/SHN1 overexpression on poplar trees
Shaneka S. Lawson
2016-01-01
Background: Interactions between plants and the environment occur primarily at the leaf level. The plant cuticle consists of a menagerie of lipids, waxes and polymers merging to form an insoluble membrane to protect plant leaves from contamination. In Arabidopsis, wax Inducer1/shine1 (WIN1/SHN1) and its family members have demonstrated roles in wax...
Code of Federal Regulations, 2010 CFR
2010-01-01
... against shining into the airplane's windows or doors. (2) The airplane must be a normal ground attitude with landing gear extended. (3) Unless the airplane is equipped with an off-wing descent means, stands... is not part of the emergency evacuation equipment of the airplane may be used to aid the participants...
GEMMs shine a light on resistance to androgen deprivation therapy for prostate cancer
Karantanos, Theodoros; Thompson, Timothy C.
2013-01-01
Summary Androgen deprivation therapy (ADT) for advanced prostate cancer inexorably leads to resistance, and clinically useful biomarkers are lacking. The value of genetically engineered mice for co-clinical studies is clearly demonstrated in a recent publication that reveals XAF1, XIAP, and SRD5A1 as novel predictive biomarkers and therapeutic targets for ADT resistance. PMID:23845440
It Takes Two Shining Lights to Brighten the Room: Peer Effects with Random Roommate Assignments
ERIC Educational Resources Information Center
Zhang, Liang; Pu, Shi
2017-01-01
We used housing assignment data from a college in China to investigate peer effects on college grades. Study results provided some evidence for peer effects in college housing units. First, peer effects through means occurred during both fall and spring semester of the first year in college, with estimated effect much larger than that in previous…
The Essential Manual for Asperger Syndrome (ASD) in the Classroom: What Every Teacher Needs to Know
ERIC Educational Resources Information Center
Hoopmann, Kathy
2015-01-01
Perfect for time-poor teachers, Kathy Hoopmann's essential handbook is an easy-to-navigate resource that promotes a positive learning environment in which students with Asperger syndrome (ASD) can thrive. Kathy's unique ability to explain the ASD mind-set shines through as her concise descriptions reveal how to recognise and develop the child's…
Life of War, Death of the Rest: The Shining Path of Cormac McCarthy's Thermonuclear America
ERIC Educational Resources Information Center
Blackmore, Tim
2009-01-01
The Bush Administration's quiet resumption of, or initiation of new, nuclear weapons programs aimed militarizing space, and erecting a missile defense shield that would have the effect of rolling back 19 years of solid detente, has gone largely unnoticed over the last eight years. Weapons makers, government officials and politicians have expressed…
"Libel Tourism" Puts British and American Defamation Standards in the Spotlight
ERIC Educational Resources Information Center
Howard, Jennifer
2008-01-01
This article reports on the College Art Association's decision to settle with a scholar who felt defamed by an article in one of its scholarly journals which shines a spotlight on so-called "libel tourism." When the College Art Association decided recently to settle rather than fight a possible libel action in Britain over a book review…
ERIC Educational Resources Information Center
Cumberland, Denise M.
2013-01-01
A corporate executive provides an amusing and reflective account on her experience of being downsized. This "day in the life" perspective documents the feelings of an individual who found herself served with "divorce papers" from a job that had, in many ways, defined her identity. Her personal story shines the spotlight on…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pawel, Steven J.
2016-01-01
In the previous report of this series, a literature review was performed to assess the potential for substantial corrosion issues associated with the proposed SHINE process conditions to produce 99Mo. Following the initial review, substantial laboratory corrosion testing was performed emphasizing immersion and vapor-phase exposure of candidate alloys in a wide variety of solution chemistries and temperatures representative of potential exposure conditions. Stress corrosion cracking was not identified in any of the exposures up to 10 days at 80°C and 10 additional days at 93°C. Mechanical properties and specimen fracture face features resulting from slow-strain rate tests further supported amore » lack of sensitivity of these alloys to stress corrosion cracking. Fluid velocity was found not to be an important variable (0 to ~3 m/s) in the corrosion of candidate alloys at room temperature and 50°C. Uranium in solution was not found to adversely influence potential erosion-corrosion. Potentially intense radiolysis conditions slightly accelerated the general corrosion of candidate alloys, but no materials were observed to exhibit an annualized rate above 10 μm/y.« less
Wu, C J; Janssen, G R
1996-10-01
The Streptomyces vinaceus viomycin phosphotransferase (vph) mRNA contains an untranslated leader with a conventional Shine-Dalgarno homology. The vph leader was removed by ligation of the vph coding sequence to the transcriptional start site of a Streptomyces or an Escherichia coli promoter, such that transcription would initiate at the first position of the vph start codon. Analysis of mRNA demonstrated that transcription initiated primarily at the A of the vph AUG translational start codon in both Streptomyces lividans and E. coli; cells expressing the unleadered vph mRNA were resistant to viomycin indicating that the Shine-Dalgarno sequence, or other features contained within the leader, was not necessary for vph translation. Addition of four nucleotides (5'-AUGC-3') onto the 5' end of the unleadered vph mRNA resulted in translation initiation from the vph start codon and the AUG triplet contained within the added sequence. Translational fusions of vph sequence to a Tn5 neo reporter gene indicated that the first 16 codons of vph coding sequence were sufficient to specify the translational start site and reading frame for expression of neomycin resistance in both E. coli and S. lividans.
Naudinot, Nicolas; Bourdier, Camille; Laforge, Marine; Paris, Céline; Bellot-Gurlet, Ludovic; Beyries, Sylvie; Thery-Parisot, Isabelle; Le Goffic, Michel
2017-01-01
The development of the Azilian in Western Europe 14,000 years ago is considered a "revolution" in Upper Paleolithic Archaeology. One of the main elements of this rapid social restructuring is the abandonment of naturalistic figurative art on portable pieces or on cave walls in the Magdalenian in favor of abstract expression on small pebbles. Recent work shows that the transformation of human societies between the Magdalenian and the Azilian was more gradual. The discovery of a new Early Azilian site with decorated stones in France supports this hypothesis. While major changes in stone tool technology between the Magdalenian and Azilian clearly mark important adaptive changes, the discovery of 45 engraved schist tablets from archaeological layers at Le Rocher de l'Impératrice attests to iconographic continuity together with special valorization of aurochs as shown by a "shining" bull depiction. This evidence suggests that some cultural features such as iconography may lag far behind technological changes. We also argue that eventual change in symbolic expression, which includes the later disappearance of figurative art, provides new insight into the probable restructuring of the societies.
Hockenberry, Adam J; Pah, Adam R; Jewett, Michael C; Amaral, Luís A N
2017-01-01
Studies dating back to the 1970s established that sequence complementarity between the anti-Shine-Dalgarno (aSD) sequence on prokaryotic ribosomes and the 5' untranslated region of mRNAs helps to facilitate translation initiation. The optimal location of aSD sequence binding relative to the start codon, the full extents of the aSD sequence and the functional form of the relationship between aSD sequence complementarity and translation efficiency have not been fully resolved. Here, we investigate these relationships by leveraging the sequence diversity of endogenous genes and recently available genome-wide estimates of translation efficiency. We show that-after accounting for predicted mRNA structure-aSD sequence complementarity increases the translation of endogenous mRNAs by roughly 50%. Further, we observe that this relationship is nonlinear, with translation efficiency maximized for mRNAs with intermediate levels of aSD sequence complementarity. The mechanistic insights that we observe are highly robust: we find nearly identical results in multiple datasets spanning three distantly related bacteria. Further, we verify our main conclusions by re-analysing a controlled experimental dataset. © 2017 The Authors.
NASA Astrophysics Data System (ADS)
Ozvenchuk, V.; Rybicki, A.
2018-05-01
The UrQMD transport model, version 3.4, is used to study the new experimental data on transverse momentum spectra of π±, K±, p and p bar produced in inelastic p + p interactions at SPS energies, recently published by the NA61/SHINE Collaboration. The comparison of model predictions to these new measurements is presented as a function of collision energy for central and forward particle rapidity intervals. In addition, the inverse slope parameters characterizing the transverse momentum distributions are extracted from the predicted spectra and compared to the corresponding values obtained from NA61/SHINE distributions, as a function of particle rapidity and collision energy. A complex pattern of deviations between the experimental data and the UrQMD model emerges. For charged pions, the fair agreement visible at top SPS energies deteriorates with the decreasing energy. For charged K mesons, UrQMD significantly underpredicts positive kaon production at lower beam momenta. It also underpredicts the central rapidity proton yield at top collision energy and overpredicts antiproton production at all considered energies. We conclude that the new experimental data analyzed in this paper still constitute a challenge for the present version of the model.
Suresh, Gorle; Srinivasan, Harini; Nanda, Shivani; Priyakumar, U Deva
2016-06-21
Riboswitches are structured RNA motifs that control gene expression by sensing the concentrations of specific metabolites and make up a promising new class of antibiotic targets. S-Adenosylmethionine (SAM)-III riboswitch, mainly found in lactic acid bacteria, is involved in regulating methionine and SAM biosynthetic pathways. SAM-III riboswitch regulates the gene expression by switching the translation process on and off with respect to the absence and presence of the SAM ligand, respectively. In this study, an attempt is made to understand the key conformational transitions involved in ligand binding using atomistic molecular dynamics (MD) simulations performed in an explicit solvent environment. G26 is found to recognize the SAM ligand by forming hydrogen bonds, whereas the absence of the ligand leads to opening of the binding pocket. Consistent with experimental results, the absence of the SAM ligand weakens the base pairing interactions between the nucleobases that are part of the Shine-Dalgarno (SD) and anti-Shine-Dalgarno (aSD) sequences, which in turn facilitates recognition of the SD sequence by ribosomes. Detailed analysis reveals that a duplex-like structure formed by nucleotides from different parts of the RNA and the adenine base of the ligand is crucial for the stability of the completely folded state in the presence of the ligand. Previous experimental studies have shown that the SAM-III riboswitch exists in equilibrium between the unfolded and partially folded states in the absence of the ligand, which completely folds upon binding of the ligand. Comparison of the results presented here to the available experimental data indicates the structures obtained using the MD simulations resemble the partially folded state. Thus, this study provides a detailed understanding of the fully and partially folded structures of the SAM-III riboswitch in the presence and absence of the ligand, respectively. This study hypothesizes a dual role for the SAM ligand, which facilitates conformational switching between partially and fully folded states by forming a stable duplex-like structure and strengthening the interactions between SD and aSD nucleotides.
ERIC Educational Resources Information Center
Harnisch, Thomas; Nassirian, Barmak; Saddler, Amber; Coleman, Art
2016-01-01
This brief examines the "triad" of state governments, the federal government and accrediting agencies and, by shining light on the unique role that state governments play in this partnership, the authors propose reforms that will strengthen the role of state governments, without neglecting the two other legs of the higher education stool.
ERIC Educational Resources Information Center
Kwon, Soonjung; Walker, David Ian; Kristjánsson, Kristján
2018-01-01
The paper illustrates how a culture of violence is perpetuated and reproduced in South Korea through schooling and argues that peace education could help transform a culture of violence to a culture of peace. Critical ethnographic methods and a framework of peace education were applied to a sample of secondary schools in South Korea to argue that…
ERIC Educational Resources Information Center
Sherman, Lee; Lewis, Bryan; Ramsey, Betsy; Tibbetts, Daniel; Kaplan, Kay; Berninger, Virginia
2003-01-01
Interviews with a learning disabled student, parent activist, teacher, tutor, and researcher reveal that learning disabilities are neurologically caused, not the result of low motivation or dysfunctional families. A variety of educational practices are explained that accommodate different learning styles of children with learning disabilities. It…
Come Rain or Shine: A Whole School Approach to Forest School
ERIC Educational Resources Information Center
Vandewalle, Martyn
2010-01-01
This article begins by describing a typical Forest School session that takes place in every class every week at The Wroxham School in Potters Bar. It goes on to outline a brief history of Forest School from its inception, its aims and ethos, and how it has been adapted for the ethos and needs of the children at Wroxham. The article also looks at…
ERIC Educational Resources Information Center
Shemberger, Melony
2017-01-01
This case study focusing on journalism curriculum in Tennessee sheds light on the obstacles that journalism schools face in efforts to include more instruction of sunshine laws into courses. Journalists use these laws to gather information to write their stories, either by attending public meetings or by filing open records requests. This study…
ERIC Educational Resources Information Center
Gill, Jennifer
2012-01-01
Every district wants its schools to shine, and more are recognizing that, in order to raise performance, they need well-trained principals who can shake up the status quo and create an environment where all students flourish. Indeed, in a six-year study analyzing data from 180 schools in nine states, researchers from the Universities of Minnesota…
NCI Core Open House Shines Spotlight on Supportive Science and Basic Research | Poster
The lobby of Building 549 at NCI at Frederick bustled with activity for two hours on Tuesday, May 1, as several dozen scientists and staff gathered for the NCI Core Open House. The event aimed to encourage discussion and educate visitors about the capabilities of the cores, laboratories, and facilities that offer support to NCI’s Center for Cancer Research.
Shinkman, R
1998-08-03
As Allegheny Health, Education and Research Foundation muddles through its high-profile bankruptcy reorganization, the spotlight of public scrutiny is now shining brightly on the system's board members, who were supposed to act as guardians of the not-for-profit system. "When things fall apart, the board members usually take the heat," says one governance expert. "And they should take the heat, since they are the final buffer."
ERIC Educational Resources Information Center
Kittelson, Andrea
2016-01-01
The purpose of this instrumental case study was to understand the ways in which the leaders of one high-achieving, large, urban high school communicate with Latino families about math with the intent to shine a light on the issue of communication with families as it relates to student achievement and the persistent math achievement gap among…
Clinical audit: shining a light on good practice.
Grainger, Angela
2010-07-01
Healthcare organisations undertake quality assurance to produce safe and effective patient care systems. Statutory quality assurance requirements are met through external reviews, monitoring and inspection processes, and each NHS trust must produce a corporate annual quality account. However, this can result in approaching audits as if they are 'tick-box activities'. This article discusses how organisations can avoid this trap by applying audit results to practice.
ERIC Educational Resources Information Center
Wigginton, Eliot
In fall 1966, Eliot Wigginton took his first teaching job in Rabun Gap-Nacoochee School, a semiprivate rural Georgia high school with both local and boarding students. This book is his account of his early struggle to control and interest his students, the genesis and development of the student-produced Foxfire publications, and his views on the…
ERIC Educational Resources Information Center
Gordon, Nora
2017-01-01
The subgroup requirements for accountability in the No Child Left Behind Act (NCLB) were designed to reveal underperformance of disadvantaged groups that could otherwise be hidden in aggregate averages. Both NCLB and its successor, the Every Student Succeeds Act (ESSA), left the choice of minimum subgroup size at the school level (n-size) for…
Evaluation of Argonne 9-cm and 10-cm Annular Centrifugal Contactors for SHINE Solution Processing
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wardle, Kent E.; Pereira, Candido; Vandegrift, George
2015-02-01
Work is in progress to evaluate the SHINE Medical Technologies process for producing Mo-99 for medical use from the fission of dissolved low-enriched uranium (LEU). This report addresses the use of Argonne annular centrifugal contactors for periodic treatment of the process solution. In a letter report from FY 2013, Pereira and Vandegrift compared the throughput and physical footprint for the two contactor options available from CINC Industries: the V-02 and V-05, which have rotor diameters of 5 cm and 12.7 cm, respectively. They suggested that an intermediately sized “Goldilocks” contactor might provide a better balance between throughput and footprint tomore » meet the processing needs for the uranium extraction (UREX) processing of the SHINE solution to remove undesired fission products. Included with the submission of this letter report are the assembly drawings for two Argonne-design contactors that are in this intermediate range—9-cm and 10-cm rotors, respectively. The 9-cm contactor (drawing number CE-D6973A, stamped February 15, 1978) was designed as a single-stage unit and built and tested in the late 1970s along with other size units, both smaller and larger. In subsequent years, a significant effort to developed annular centrifugal contactors was undertaken to support work at Hanford implementing the transuranic extraction (TRUEX) process. These contactors had a 10-cm rotor diameter and were fully designed as multistage units with four stages per assembly (drawing number CMT-E1104, stamped March 14, 1990). From a technology readiness perspective, these 10-cm units are much farther ahead in the design progression and, therefore, would require significantly less re-working to make them ready for UREX deployment. Additionally, the overall maximum throughput of ~12 L/min is similar to that of the 9-cm unit (10 L/min), and the former could be efficiently operated over much of the same range of throughput. As a result, only the 10-cm units are considered here, though drawings are provided for the 9-cm unit for reference.« less
Wilson, Dawn K.; Schneider, Elizabeth M.; Alia, Kassandra A.
2013-01-01
Objective This study examined parenting variables (communication, monitoring) as moderators of a family-based intervention for reducing sedentary behavior (SB) in African American adolescents. As a secondary aim, a similar model was tested using adolescent weight status as the outcome. Methods African American adolescents (n = 73; 12.45 ± 1.45 years; 60% girls; 63% overweight/obese) and caregivers were randomized to a 6-week interactive, parent-based intervention or general health condition. Parent–adolescent communication and monitoring of health behaviors were self-reported by parents. Adolescent SB was self-reported by youth. Results There was a significant intervention by communication interaction, such that intervention families with more positive communication showed lower adolescent SB than those with less positive communication or those in the comparison condition. No effects were found for monitoring on SB or for the model with weight status as the outcome. Conclusions Parent–adolescent communication may be an effective component to integrate into health promotion programs for African American adolescents. PMID:23685450
Giant light-harvesting nanoantenna for single-molecule detection in ambient light
Trofymchuk, Kateryna; Reisch, Andreas; Didier, Pascal; Fras, François; Gilliot, Pierre; Mely, Yves; Klymchenko, Andrey S.
2017-01-01
Here, we explore the enhancement of single molecule emission by polymeric nano-antenna that can harvest energy from thousands of donor dyes to a single acceptor. In this nano-antenna, the cationic dyes are brought together in very close proximity using bulky counterions, thus enabling ultrafast diffusion of excitation energy (≤30 fs) with minimal losses. Our 60-nm nanoparticles containing >10,000 rhodamine-based donor dyes can efficiently transfer energy to 1-2 acceptors resulting in an antenna effect of ~1,000. Therefore, single Cy5-based acceptors become 25-fold brighter than quantum dots QD655. This unprecedented amplification of the acceptor dye emission enables observation of single molecules at illumination powers (1-10 mW cm-2) that are >10,000-fold lower than typically required in single-molecule measurements. Finally, using a basic setup, which includes a 20X air objective and a sCMOS camera, we could detect single Cy5 molecules by simply shining divergent light on the sample at powers equivalent to sunlight. PMID:28983324
Diffusion Behaviour in Superconducting Ti/Au bilayers for SAFARI TES Detectors
NASA Astrophysics Data System (ADS)
van der Heijden, N. J.; Khosropanah, P.; van der Kuur, J.; Ridder, M. L.
2014-08-01
Controlling the critical temperature () of Ti/Au bilayers is vital in the development of practical TES detectors. Previously empirical studies have been done on aging effects in Ti/Au and other superconducting bilayers but no link with theory has been made. Here we attempt to explain the change in with a diffusion mechanism. The change in has been measured for a set of Ti/Au bilayer samples that have been given a variety of bake-out treatments, where we found a trend that can be partly explained by an inter-diffusion mechanism. With an empirical model based on diffusion a safe zone can be defined as a region of bake-out treatments, where the is not affected beyond the requirements. This will shine light on the bake-out and the storage condition boundaries of these detectors.
Action recognition via cumulative histogram of multiple features
NASA Astrophysics Data System (ADS)
Yan, Xunshi; Luo, Yupin
2011-01-01
Spatial-temporal interest points (STIPs) are popular in human action recognition. However, they suffer from difficulties in determining size of codebook and losing much information during forming histograms. In this paper, spatial-temporal interest regions (STIRs) are proposed, which are based on STIPs and are capable of marking the locations of the most ``shining'' human body parts. In order to represent human actions, the proposed approach takes great advantages of multiple features, including STIRs, pyramid histogram of oriented gradients and pyramid histogram of oriented optical flows. To achieve this, cumulative histogram is used to integrate dynamic information in sequences and to form feature vectors. Furthermore, the widely used nearest neighbor and AdaBoost methods are employed as classification algorithms. Experiments on public datasets KTH, Weizmann and UCF sports show that the proposed approach achieves effective and robust results.
Nanoscale surface modification of glass using a 1064 nm pulsed laser
NASA Astrophysics Data System (ADS)
Theppakuttai, Senthil; Chen, Shaochen
2003-07-01
We report a method to produce nanopatterns on borosilicate glass by a Nd:yttrium-aluminum-garnet laser (10 ns, 1064 nm), using silica nanospheres. Nonlinear absorption of the enhanced optical field between the spheres and glass sample is believed to be the primary reason for the creation of nanofeatures on the glass substrate. By shining the laser beam from the backside of the glass sample, the scattering effects are minimized and only the direct field enhancement due to the spheres is utilized for surface patterning. To confirm this, calculations based on the Mie scattering theory were performed, and the resulting intensity as a function of scattering angles are presented. The nanofeatures thus obtained by this method are 350 nm in diameter and the distance between them is around 640 nm, which is same as the size of spheres used.
Wireless Passive Stimulation of Engineered Cardiac Tissues.
Liu, Shiyi; Navaei, Ali; Meng, Xueling; Nikkhah, Mehdi; Chae, Junseok
2017-07-28
We present a battery-free radio frequency (RF) microwave activated wireless stimulator, 25 × 42 × 1.6 mm 3 on a flexible substrate, featuring high current delivery, up to 60 mA, to stimulate engineered cardiac tissues. An external antenna shines 2.4 GHz microwave, which is modulated by an inverted pulse to directly control the stimulating waveform, to the wireless passive stimulator. The stimulator is equipped with an on-board antenna, multistage diode multipliers, and a control transistor. Rat cardiomyocytes, seeded on electrically conductive gelatin-based hydrogels, demonstrate synchronous contractions and Ca 2+ transients immediately upon stimulation. Notably, the stimulator output voltage and current profiles match the tissue contraction frequency within 0.5-2 Hz. Overall, our results indicate the promising potential of the proposed wireless passive stimulator for cardiac stimulation and therapy by induction of precisely controlled and synchronous contractions.
No Photon Left Behind: Advanced Optics at ARPA-E for Buildings and Solar Energy
NASA Astrophysics Data System (ADS)
Branz, Howard M.
2015-04-01
Key technology challenges in building efficiency and solar energy utilization require transformational optics, plasmonics and photonics technologies. We describe advanced optical technologies funded by the Advanced Research Projects Agency - Energy. Buildings technologies include a passive daytime photonic cooler, infra-red computer vision mapping for energy audit, and dual-band electrochromic windows based on plasmonic absorption. Solar technologies include novel hybrid energy converters that combine high-efficiency photovoltaics with concentrating solar thermal collection and storage. Because the marginal cost of thermal energy storage is low, these systems enable generation of inexpensive and dispatchable solar energy that can be deployed when the sun doesn't shine. The solar technologies under development include nanoparticle plasmonic spectrum splitting, Rugate filter interference structures and photovoltaic cells that can operate efficiently at over 400° C.
Epel, Elissa S.; Kristeller, Jean; Moran, Patricia J.; Dallman, Mary; Lustig, Robert H.; Acree, Michael; Bacchetti, Peter; Laraia, Barbara A.; Hecht, Frederick M.; Daubenmier, Jennifer
2016-01-01
We evaluated changes in mindful eating as a potential mechanism underlying the effects of a mindfulness-based intervention for weight loss on eating of sweet foods and fasting glucose levels. We randomized 194 obese individuals (M age = 47.0 ± 12.7 years; BMI = 35.5 ± 3.6; 78 % women) to a 5.5-month diet-exercise program with or without mindfulness training. The mindfulness group, relative to the active control group, evidenced increases in mindful eating and maintenance of fasting glucose from baseline to 12-month assessment. Increases in mindful eating were associated with decreased eating of sweets and fasting glucose levels among mindfulness group participants, but this association was not statistically significant among active control group participants. Twelve-month increases in mindful eating partially mediated the effect of intervention arm on changes in fasting glucose levels from baseline to 12-month assessment. Increases in mindful eating may contribute to the effects of mindfulness-based weight loss interventions on eating of sweets and fasting glucose levels. PMID:26563148
Mason, Ashley E; Epel, Elissa S; Kristeller, Jean; Moran, Patricia J; Dallman, Mary; Lustig, Robert H; Acree, Michael; Bacchetti, Peter; Laraia, Barbara A; Hecht, Frederick M; Daubenmier, Jennifer
2016-04-01
We evaluated changes in mindful eating as a potential mechanism underlying the effects of a mindfulness-based intervention for weight loss on eating of sweet foods and fasting glucose levels. We randomized 194 obese individuals (M age = 47.0 ± 12.7 years; BMI = 35.5 ± 3.6; 78% women) to a 5.5-month diet-exercise program with or without mindfulness training. The mindfulness group, relative to the active control group, evidenced increases in mindful eating and maintenance of fasting glucose from baseline to 12-month assessment. Increases in mindful eating were associated with decreased eating of sweets and fasting glucose levels among mindfulness group participants, but this association was not statistically significant among active control group participants. Twelve-month increases in mindful eating partially mediated the effect of intervention arm on changes in fasting glucose levels from baseline to 12-month assessment. Increases in mindful eating may contribute to the effects of mindfulness-based weight loss interventions on eating of sweets and fasting glucose levels.
ERIC Educational Resources Information Center
Anderson, Catherine, Ed.
The writings of both teachers and students participating in the New Americans Homeowners Project, a project combining English-as-a-Second-Language (ESL) instruction and information on first-time home-buying for immigrants in language minority groups are presented. The project provided training and technical assistance to ESL teachers, and reached…
ERIC Educational Resources Information Center
Oregon Department of Education, 2016
2016-01-01
This brief highlights the importance of using a measure like chronic absenteeism, rather than average daily attendance, in order to identify concerning patterns in elementary attendance rates. The chronic absenteeism measurement is better able to shine a light on the number of individual students struggling with attendance. Subsequent briefs in…
Small Towns, Big Plans: Building a Stronger Network of Workforce Education Programs in Rural America
ERIC Educational Resources Information Center
Pulley, John
2014-01-01
John Pulley begins this article by sharing the story of Richard Quiroga, a shining example of what can happen when an at-risk student in an economically disadvantaged region gets the right training at the right time. As a young man, Quiroga was living on his own and at risk of getting sucked into the whirlpool of poverty and despair that often…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aduszkiewicz, A.; Ali, Y.; Andronov, E.
Results on two-particle ΔηΔΦ correlations in inelastic p + p interactions at 20, 31, 40, 80, and 158 GeV/c are presented. The measurements were performed using the large acceptance NA61/SHINE hadron spectrometer at the CERN Super Proton Synchrotron. The data show structures which can be attributed mainly to effects of resonance decays, momentum conservation, and quantum statistics. Furthermore, the results are compared with the Epos and UrQMD models.
ERIC Educational Resources Information Center
Chiang, I-Tsun; Chen, Mei-Li
2011-01-01
The purpose of this study was to employ complexity theory as a theoretical framework and technology to facilitate the development of a life-long learning model for non-working time in the interdependent homes for adults with Autism Spectrum Disorders (ASD). A "Shining Star Sustainable Action Project" of the ROC Foundation for Autistic…
ERIC Educational Resources Information Center
Fishman, Shira; Henderson, Whitney; Irish, Jamie; Lyons, Katie; Ross, Leslie
2012-01-01
Founded by TNTP, the Fishman Prize for Superlative Classroom Practice is an annual award for the nation's best teachers in high-poverty public schools. The goal is to shine a spotlight on great teaching and amplify the voices of some of the nation's best educators so that others can gain insight into their remarkable classrooms. No more than five…
Tom Cruise is dangerous and irresponsible
Neill, Ushma S.
2005-01-01
Yes, even the JCI can weigh in on celebrity gossip, but hopefully without becoming a tabloid. Rather, we want to shine a light on the reckless comments actor Tom Cruise has recently made that psychiatry is a “quack” field and his belief that postpartum depression cannot be treated pharmacologically. We can only hope that his influence as a celebrity does not hold back those in need of psychiatric treatment. PMID:16075033
GEMMs shine a light on resistance to androgen deprivation therapy for prostate cancer.
Karantanos, Theodoros; Thompson, Timothy C
2013-07-08
Androgen deprivation therapy (ADT) for advanced prostate cancer inexorably leads to resistance, and clinically useful biomarkers are lacking. The value of genetically engineered mice for coclinical studies is clearly demonstrated in a recent publication that reveals XAF1, XIAP, and SRD5A1 as novel predictive biomarkers and therapeutic targets for ADT resistance. Copyright © 2013 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Aller, Lawrence H.
1991-09-01
1. Introducing stars and nebulae; 2. Stellar rainbows; 3. Atoms and molecules; 4. The climate in a stellar atmosphere; 5. Analysing the stars; 6. Dwarfs, giants, and supergiants; 7. What makes a star shine?; 8. The youth and middle age of a common star; 9. Wind, dust and pulsations; 10. A star's last hurray?; 11. The interstellar medium and gaseous nebulae; 12. Uncommon stars and their sometimes violent behaviour; 13. High energy astronomy.
A two particle hidden sector and the oscillations with photons
NASA Astrophysics Data System (ADS)
Alvarez, Pedro D.; Arias, Paola; Maldonado, Carlos
2018-01-01
We present a detailed study of the oscillations and optical properties for vacuum, in a model for the dark sector that contains axion-like particles and hidden photons. We provide bounds for the couplings versus the mass, using current results from ALPS-I and PVLAS. We also discuss the challenges for the detection of models with more than one hidden particle in light shining trough wall-like experiments.
Measurements of the global 21-cm signal from the Cosmic Dawn
NASA Astrophysics Data System (ADS)
Bernardi, Gianni
2018-05-01
The sky-averaged (global) 21-cm signal is a very promising probe of the Cosmic Dawn, when the first luminous sources were formed and started to shine in a substantially neutral intergalactic medium. I here report on the status and early result of the Large-Aperture Experiment to Detect the Dark Age that focuses on observations of the global 21-cm signal in the 16 <~ z <~ 30 range.
New estimation method of neutron skyshine for a high-energy particle accelerator
NASA Astrophysics Data System (ADS)
Oh, Joo-Hee; Jung, Nam-Suk; Lee, Hee-Seock; Ko, Seung-Kook
2016-09-01
A skyshine is the dominant component of the prompt radiation at off-site. Several experimental studies have been done to estimate the neutron skyshine at a few accelerator facilities. In this work, the neutron transports from a source place to off-site location were simulated using the Monte Carlo codes, FLUKA and PHITS. The transport paths were classified as skyshine, direct (transport), groundshine and multiple-shine to understand the contribution of each path and to develop a general evaluation method. The effect of each path was estimated in the view of the dose at far locations. The neutron dose was calculated using the neutron energy spectra obtained from each detector placed up to a maximum of 1 km from the accelerator. The highest altitude of the sky region in this simulation was set as 2 km from the floor of the accelerator facility. The initial model of this study was the 10 GeV electron accelerator, PAL-XFEL. Different compositions and densities of air, soil and ordinary concrete were applied in this calculation, and their dependences were reviewed. The estimation method used in this study was compared with the well-known methods suggested by Rindi, Stevenson and Stepleton, and also with the simple code, SHINE3. The results obtained using this method agreed well with those using Rindi's formula.
Neutral beam dump with cathodic arc titanium gettering
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smirnov, A.; Korepanov, S. A.; Putvinski, S.
An incomplete neutral beam capture can degrade the plasma performance in neutral beam driven plasma machines. The beam dumps mitigating the shine-through beam recycling must entrap and retain large particle loads while maintaining the beam-exposed surfaces clean of the residual impurities. The cathodic arc gettering, which provides high evaporation rate coupled with a fast time response, is a powerful and versatile technique for depositing clean getter films in vacuum. A compact neutral beam dump utilizing the titanium arc gettering was developed for a field-reversed configuration plasma sustained by 1 MW, 20-40 keV neutral hydrogen beams. The titanium evaporator features amore » new improved design. The beam dump is capable of handling large pulsed gas loads, has a high sorption capacity, and is robust and reliable. With the beam particle flux density of 5 x 10{sup 17} H/(cm{sup 2}s) sustained for 3-10 ms, the beam recycling coefficient, defined as twice the ratio of the hydrogen molecular flux leaving the beam dump to the incident flux of high-energy neutral atoms, is {approx}0.7. The use of the beam dump allows us to significantly reduce the recycling of the shine-through neutral beam as well as to improve the vacuum conditions in the machine.« less
The Proof of the ``Vortex Theory of Matter''
NASA Astrophysics Data System (ADS)
Moon, Russell
2009-11-01
According to the Vortex Theory, protons and electrons are three-dimensional holes connected by fourth-dimensional vortices. It was further theorized that when photons are absorbed then readmitted by atoms, the photon is absorbed into the proton, moves through the fourth-dimensional vortex, then reemerges back into three-dimensional space through the electron. To prove this hypothesis, an experiment was conducted using a hollow aluminum sphere containing a powerful permanent magnet suspended directly above a zinc plate. Ultraviolet light was then shined upon the zinc. The zinc emits electrons via the photoelectric effect that are attracted to the surface of the aluminum sphere. The sphere was removed from above the zinc plate and repositioned above a sensitive infrared digital camera in another room. The ball and camera were placed within a darkened box inside a Faraday cage. Light was shined upon the zinc plate and the picture taken by the camera was observed. When the light was turned on above the zinc plate in one room, the camera recorded increased light coming from the surface of the sphere within the other room; when the light was turned off, the intensity of the infrared light coming from the surface of the sphere was suddenly diminished. Five other tests were then performed to eliminate other possible explanations such as quantum-entangled electrons.
The Proof of the ``Vortex Theory of Matter''
NASA Astrophysics Data System (ADS)
Gridnev, Konstantin; Moon, Russell; Vasiliev, Victor
2009-11-01
According to the Vortex Theory, protons and electrons are three-dimensional holes connected by fourth-dimensional vortices. It was further theorized that when photons are absorbed then readmitted by atoms, the photon is absorbed into the proton, moves through the fourth-dimensional vortex, then reemerges back into three-dimensional space through the electron^2. To prove this hypothesis, an experiment was conducted using a hollow aluminum sphere containing a powerful permanent magnet suspended directly above a zinc plate. Ultraviolet light was then shined upon the zinc. The zinc emits electrons via the photoelectric effect that are attracted to the surface of the aluminum sphere. The sphere was removed from above the zinc plate and repositioned above a sensitive infrared digital camera in another room. The ball and camera were placed within a darkened box inside a Faraday cage. Light was shined upon the zinc plate and the picture taken by the camera was observed. When the light was turned on above the zinc plate in one room, the camera recorded increased light coming from the surface of the sphere within the other room; when the light was turned off, the intensity of the infrared light coming from the surface of the sphere was suddenly diminished. Five other tests were then performed to eliminate other possible explanations such as quantum-entangled electrons.
The Proof of the ``Vortex Theory of Matter''
NASA Astrophysics Data System (ADS)
Gridnev, Konstantin; Moon, Russell; Vasiliev, Victor
2009-10-01
According to the Vortex Theory, protons and electrons are three-dimensional holes connected by fourth-dimensional vortices. It was further theorized that when photons are absorbed then readmitted by atoms, the photon is absorbed into the proton, moves through the fourth-dimensional vortex, then reemerges back into three-dimensional space through the electron^2. To prove this hypothesis, an experiment was conducted using a hollow aluminum sphere containing a powerful permanent magnet suspended directly above a zinc plate. Ultraviolet light was then shined upon the zinc. The zinc emits electrons via the photoelectric effect that are attracted to the surface of the aluminum sphere. The sphere was removed from above the zinc plate and repositioned above a sensitive infrared digital camera in another room. The ball and camera were placed within a darkened box inside a Faraday cage. Light was shined upon the zinc plate and the picture taken by the camera was observed. When the light was turned on above the zinc plate in one room, the camera recorded increased light coming from the surface of the sphere within the other room; when the light was turned off, the intensity of the infrared light coming from the surface of the sphere was suddenly diminished. Five other tests were then performed to eliminate other possible explanations such as quantum-entangled electrons.
The Proof of the ``Vortex Theory of Matter''
NASA Astrophysics Data System (ADS)
Moon, Russell; Gridnev, Konstantin; Vasiliev, Victor
2010-02-01
According to the Vortex Theory, protons and electrons are three-dimensional holes connected by fourth-dimensional vortices. It was further theorized that when photons are absorbed then readmitted by atoms, the photon is absorbed into the proton, moves through the fourth-dimensional vortex, then reemerges back into three-dimensional space through the electron. To prove this hypothesis, an experiment was conducted using a hollow aluminum sphere containing a powerful permanent magnet suspended directly above a zinc plate. Ultraviolet light was then shined upon the zinc. The zinc emits electrons via the photoelectric effect that are attracted to the surface of the aluminum sphere. The sphere was removed from above the zinc plate and repositioned above a sensitive infrared digital camera in another room. The ball and camera were placed within a darkened box inside a Faraday cage. Light was shined upon the zinc plate and the picture taken by the camera was observed. When the light was turned on above the zinc plate in one room, the camera recorded increased light coming from the surface of the sphere within the other room; when the light was turned off, the intensity of the infrared light coming from the surface of the sphere was suddenly diminished. Five other tests were then performed to eliminate other possible explanations such as quantum-entangled electrons. )
Vasquez, Kevin A; Hatridge, Taylor A; Curtis, Nicholas C; Contreras, Lydia M
2016-02-19
Recent studies have demonstrated that effective protein production requires coordination of multiple cotranslational cellular processes, which are heavily affected by translation timing. Until recently, protein engineering has focused on codon optimization to maximize protein production rates, mostly considering the effect of tRNA abundance. However, as it relates to complex multidomain proteins, it has been hypothesized that strategic translational pauses between domains and between distinct individual structural motifs can prevent interactions between nascent chain fragments that generate kinetically trapped misfolded peptides and thereby enhance protein yields. In this study, we introduce synthetic transient pauses between structural domains in a heterologous model protein based on designed patterns of affinity between the mRNA and the anti-Shine-Dalgarno (aSD) sequence on the ribosome. We demonstrate that optimizing translation attenuation at domain boundaries can predictably affect solubility patterns in bacteria. Exploration of the affinity space showed that modifying less than 1% of the nucleotides (on a small 12 amino acid linker) can vary soluble protein yields up to ∼7-fold without altering the primary sequence of the protein. In the context of longer linkers, where a larger number of distinct structural motifs can fold outside the ribosome, optimal synonymous codon variations resulted in an additional 2.1-fold increase in solubility, relative to that of nonoptimized linkers of the same length. While rational construction of 54 linkers of various affinities showed a significant correlation between protein solubility and predicted affinity, only weaker correlations were observed between tRNA abundance and protein solubility. We also demonstrate that naturally occurring high-affinity clusters are present between structural domains of β-galactosidase, one of Escherichia coli's largest native proteins. Interdomain ribosomal affinity is an important factor that has not previously been explored in the context of protein engineering.
Italian Present-day Stress Indicators: IPSI Database
NASA Astrophysics Data System (ADS)
Mariucci, M. T.; Montone, P.
2017-12-01
In Italy, since the 90s of the last century, researches concerning the contemporary stress field have been developing at Istituto Nazionale di Geofisica e Vulcanologia (INGV) with local and regional scale studies. Throughout the years many data have been analysed and collected: now they are organized and available for an easy end-use online. IPSI (Italian Present-day Stress Indicators) database, is the first geo-referenced repository of information on the crustal present-day stress field maintained at INGV through a web application database and website development by Gabriele Tarabusi. Data consist of horizontal stress orientations analysed and compiled in a standardized format and quality-ranked for reliability and comparability on a global scale with other database. Our first database release includes 855 data records updated to December 2015. Here we present an updated version that will be released in 2018, after new earthquake data entry up to December 2017. The IPSI web site (http://ipsi.rm.ingv.it/) allows accessing data on a standard map viewer and choose which data (category and/or quality) to plot easily. The main information of each single element (type, quality, orientation) can be viewed simply going over the related symbol, all the information appear by clicking the element. At the same time, simple basic information on the different data type, tectonic regime assignment, quality ranking method are available with pop-up windows. Data records can be downloaded in some common formats, moreover it is possible to download a file directly usable with SHINE, a web based application to interpolate stress orientations (http://shine.rm.ingv.it). IPSI is mainly conceived for those interested in studying the characters of Italian peninsula and surroundings although Italian data are part of the World Stress Map (http://www.world-stress-map.org/) as evidenced by many links that redirect to this database for more details on standard practices in this field.
Centrifugal contactor operations for UREX process flowsheet. An update
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pereira, Candido; Vandegrift, George F.
2014-08-01
The uranium extraction (UREX) process separates uranium, technetium, and a fraction of the iodine from the other components of the irradiated fuel in nitric acid solution. In May 2012, the time, material, and footprint requirements for treatment of 260 L batches of a solution containing 130 g-U/L were evaluated for two commercial annular centrifugal contactors from CINC Industries. These calculated values were based on the expected volume and concentration of fuel arising from treatment of a single target solution vessel (TSV). The general conclusions of that report were that a CINC V-2 contactor would occupy a footprint of 3.2 mmore » 2 (0.25 m x 15 m) if each stage required twice the nominal footprint of an individual stage, and approximately 1,131 minutes or nearly 19 hours is required to process all of the feed solution. A CINC V-5 would require approximately 9.9 m 2 (0.4 m x 25 m) of floor space but would require only 182 minutes or ~ 3 hours to process the spent target solution. Subsequent comparison with the Modular Caustic Side Solvent Extraction Unit (MCU) at Savannah River Site (SRS) in October 2013 suggested that a more compact arrangement is feasible, and the linear dimension for the CINC V-5 may be reduced to about 8 m; a comparable reduction for the CINC V-2 yields a length of 5 m. That report also described an intermediate-scale (10 cm) contactor design developed by Argonne in the early 1980s that would better align with the SHINE operations as they stood in May 2012. In this report, we revisit the previous evaluation of contactor operations after discussions with CINC Industries and analysis of the SHINE process flow diagrams for the cleanup of the TSV, which were not available at the time of the first assessment.« less
Mason, Ashley E.; Epel, Elissa S.; Aschbacher, Kirstin; Lustig, Robert H.; Acree, Michael; Kristeller, Jean; Cohn, Michael; Dallman, Mary; Moran, Patricia J.; Bacchetti, Peter; Laraia, Barbara; Hecht, Frederick M.; Daubenmier, Jennifer
2016-01-01
Many individuals with obesity report overeating despite intentions to maintain or lose weight. Two barriers to long-term weight loss are reward-driven eating, which is characterized by a lack of control over eating, a preoccupation with food, and a lack of satiety; and psychological stress. Mindfulness training may address these barriers by promoting awareness of hunger and satiety cues, self-regulatory control, and stress reduction. We examined these two barriers as potential mediators of weight loss in the Supporting Health by Integrating Nutrition and Exercise (SHINE) randomized controlled trial, which compared the effects of a 5.5-month diet and exercise intervention with or without mindfulness training on weight loss among adults with obesity. Intention-to-treat multiple mediation models tested whether post-intervention reward-driven eating and psychological stress mediated the impact of intervention arm on weight loss at 12-and 18-months post-baseline among 194 adults with obesity (BMI: 30–45). Mindfulness (relative to control) participants had significant reductions in reward-driven eating at 6 months (post-intervention), which, in turn, predicted weight loss at 12 months. Post-intervention reward-driven eating mediated 47.1% of the total intervention arm effect on weight loss at 12 months [β=-0.06, SE(β)=0.03, p=.030, 95% CI (−0.12, −0.01)]. This mediated effect was reduced when predicting weight loss at 18 months (p=.396), accounting for 23.0% of the total intervention effect, despite similar weight loss at 12 months. Psychological stress did not mediate the effect of intervention arm on weight loss at 12 or 18 months. In conclusion, reducing reward-driven eating, which can be achieved using a diet and exercise intervention that includes mindfulness training, may promote weight loss (clinicaltrials.gov registration: NCT00960414). PMID:26867697
Mason, Ashley E; Epel, Elissa S; Aschbacher, Kirstin; Lustig, Robert H; Acree, Michael; Kristeller, Jean; Cohn, Michael; Dallman, Mary; Moran, Patricia J; Bacchetti, Peter; Laraia, Barbara; Hecht, Frederick M; Daubenmier, Jennifer
2016-05-01
Many individuals with obesity report over eating despite intentions to maintain or lose weight. Two barriers to long-term weight loss are reward-driven eating, which is characterized by a lack of control over eating, a preoccupation with food, and a lack of satiety; and psychological stress. Mindfulness training may address these barriers by promoting awareness of hunger and satiety cues, self-regulatory control, and stress reduction. We examined these two barriers as potential mediators of weight loss in the Supporting Health by Integrating Nutrition and Exercise (SHINE) randomized controlled trial, which compared the effects of a 5.5-month diet and exercise intervention with or without mindfulness training on weight loss among adults with obesity. Intention-to-treat multiple mediation models tested whether post-intervention reward-driven eating and psychological stress mediated the impact of intervention arm on weight loss at 12- and 18-months post-baseline among 194 adults with obesity (BMI: 30-45). Mindfulness (relative to control) participants had significant reductions in reward-driven eating at 6 months (post-intervention), which, in turn, predicted weight loss at 12 months. Post-intervention reward-driven eating mediated 47.1% of the total intervention arm effect on weight loss at 12 months [β = -0.06, SE(β) = 0.03, p = .030, 95% CI (-0.12, -0.01)]. This mediated effect was reduced when predicting weight loss at 18 months (p = .396), accounting for 23.0% of the total intervention effect, despite similar weight loss at 12 months. Psychological stress did not mediate the effect of intervention arm on weight loss at 12 or 18 months. In conclusion, reducing reward-driven eating, which can be achieved using a diet and exercise intervention that includes mindfulness training, may promote weight loss (clinicaltrials.gov registration: NCT00960414). Published by Elsevier Ltd.
Accetto, Tomaž; Avguštin, Gorazd
2011-01-01
The Shine-Dalgarno (SD) sequence is a key element directing the translation to initiate at the authentic start codons and also enabling translation initiation to proceed in 5′ untranslated mRNA regions (5′-UTRs) containing moderately strong secondary structures. Bioinformatic analysis of almost forty genomes from the major bacterial phylum Bacteroidetes revealed, however, a general absence of SD sequence, drop in GC content and consequently reduced tendency to form secondary structures in 5′-UTRs. The experiments using the Prevotella bryantii TC1-1 expression system were in agreement with these findings: neither addition nor omission of SD sequence in the unstructured 5′-UTR affected the level of the reporter protein, non-specific nuclease NucB. Further, NucB level in P. bryantii TC1-1, contrary to hMGFP level in Escherichia coli, was five times lower when SD sequence formed part of the secondary structure with a folding energy -5,2 kcal/mol. Also, the extended SD sequences did not affect protein levels as in E. coli. It seems therefore that a functional SD interaction does not take place during the translation initiation in P. bryanttii TC1-1 and possibly other members of phylum Bacteroidetes although the anti SD sequence is present in 16S rRNA genes of their genomes. We thus propose that in the absence of the SD sequence interaction, the selection of genuine start codons in Bacteroidetes is accomplished by binding of ribosomal protein S1 to unstructured 5′-UTR as opposed to coding region which is inaccessible due to mRNA secondary structure. Additionally, we found that sequence logos of region preceding the start codons may be used as taxonomical markers. Depending on whether complete sequence logo or only part of it, such as information content and base proportion at specific positions, is used, bacterial genera or families and in some cases even bacterial phyla can be distinguished. PMID:21857964
Our Roads, A Large Thermoelectric Generator
NASA Astrophysics Data System (ADS)
Weiss, I.
2017-12-01
If asphalt can heat up from the solar radiation shining onto it directly, then it will be able to heat water in pipes within the pavement. The heat from the warm water can then be harvested into usable electrical energy, because heat energy can be transformed into electrical energy using the Seebeck Effect. The Seebeck Effect is when a temperature difference causes electrons to move away from the heat, creating an electrical charge. My experiment showed my research-based hypothesis correct. I hypothesized that if asphalt can heat up from the solar radiation shining onto it directly, then it would be able to warm a water system and usable energy could be harvested, because heat energy can be transformed into electrical energy. Asphalt pavement does not reflect the sunlight and hence heats up faster than a light surface that would reflect the sunlight. This means the asphalt absorbs the sunlight and gives off heat, which is wasted energy. By turning heat energy into electricity, cities can provide a source of clean, green energy and reduce their reliance on fossil fuels. The heat given off by asphalt increases the temperature of the air around, contributing to what is known as the urban heat island effect. This heating contributes to the formation of smog and ozone depletion. With the population still growing this would mean increasing city sizes, greater heat island effect and hence an increase in smog and ozone depletion. By harvesting the heat energy in the pavement through my setup, cities can not only create green energy but also reduce the heat radiated from pavement. Converting my system to a neighborhood street would produce higher output. My street measures 800 feet long by 35 feet wide. That gives us 28,000 square feet. At the rate of 5 volts per minute for a 2 square foot area, my street would be able to produce 70,000 volts per minute.
2017-12-08
Two stars shine through the center of a ring of cascading dust in this image taken by the NASA/ESA Hubble Space Telescope. The star system is named DI Cha, and while only two stars are apparent, it is actually a quadruple system containing two sets of binary stars. As this is a relatively young star system it is surrounded by dust. The young stars are molding the dust into a wispy wrap. The host of this alluring interaction between dust and star is the Chamaeleon I dark cloud — one of three such clouds that comprise a large star-forming region known as the Chamaeleon Complex. DI Cha's juvenility is not remarkable within this region. In fact, the entire system is among not only the youngest but also the closest collections of newly formed stars to be found and so provides an ideal target for studies of star formation. Image credit: ESA/Hubble & NASA, Acknowledgement: Judy Schmidt NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Imagine the Feeling: An Aesthetic Science of Psychology.
Quigua, Fernando; Clegg, Joshua W
2015-09-01
We claim that static trait models have dominated contemporary personality psychology but fail to reflect adequately the persons they depict. Beginning from, but moving well beyond, this critique of the five factor model (and the personality psychology field over which it reigns), we shine an aesthetic and critical light on psychology's wider failings. We review the linguistic and methodological features that have undermined the discipline's faithful understandings of human beings and their experience. In its place, we champion an aesthetic (as opposed to an an-esthetic) science of the person, one that is responsive in spirit and in practice to the emotional and imaginative life of participants and to the contexts in which they move. Specifically, we suggest that the images of fantasy and of ordinary metaphor may afford poetic understandings of participant experience that surpass those produced by literal, discursive description. We also hold that these images may offer us the most sensitive and faithful expressions of how social and environmental contexts-and so-called structural and discursive realities-are felt. The paper concludes by sketching several methodological trajectories that may stimulate researcher imagination and empathy, making research more faithful to participants and the reaches of their experience. Research practices informed by feeling and image in this way may generate new knowledge as well as new obligations.
Energy Budget: Earth's Most Important and Least Appreciated Planetary Attribute
NASA Technical Reports Server (NTRS)
Chambers, Lin; Bethea, Katie
2013-01-01
The energy budget involves more than one kind of energy. People can sense this energy in different ways, depending on what type of energy it is. We see visible light using our eyes. We feel infrared energy using our skin (such as around a campfire). We know some species of animals can see ultraviolet light and portions of the infrared spectrum. NASA satellites use instruments that can "see" different parts of the electromagnetic spectrum to observe various processes in the Earth system, including the energy budget. The Sun is a very hot ball of plasma emitting large amounts of energy. By the time it reaches Earth, this energy amounts to about 340 Watts for every square meter of Earth on average. That's almost 6 60-Watt light bulbs for every square meter of Earth! With all of that energy shining down on the Earth, how does our planet maintain a comfortable balance that allows a complex ecosystem, including humans, to thrive? The key thing to remember is the Sun - hot though it is - is a tiny part of Earth's environment. Earth's energy budget is a critical but little understood aspect of our planetary home. NASA is actively studying this important Earth system feature, and sharing data and knowledge about it with the education community.
2017-12-08
Here we see the spectacular cosmic pairing of the star Hen 2-427 — more commonly known as WR 124 — and the nebula M1-67 which surrounds it. Both objects, captured here by the NASA/ESA Hubble Space Telescope are found in the constellation of Sagittarius and lie 15,000 light-years away. The star Hen 2-427 shines brightly at the very center of this explosive image and around the hot clumps of surrounding gas that are being ejected into space at over 93,210 miles (150,000 km) per hour. Hen 2-427 is a Wolf–Rayet star, named after the astronomers Charles Wolf and Georges Rayet. Wolf–Rayet are super-hot stars characterized by a fierce ejection of mass. The nebula M1-67 is estimated to be no more than 10,000 years old — just a baby in astronomical terms — but what a beautiful and magnificent sight it makes. Image credit: ESA/Hubble & NASA, Acknowledgement: Judy Schmidt NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Ares I-X Ground Diagnostic Prototype
NASA Technical Reports Server (NTRS)
Schwabacher, Mark; Martin, Rodney; Waterman, Robert; Oostdyk, Rebecca; Ossenfort, John; Matthews, Bryan
2010-01-01
Automating prelaunch diagnostics for launch vehicles offers three potential benefits. First, it potentially improves safety by detecting faults that might otherwise have been missed so that they can be corrected before launch. Second, it potentially reduces launch delays by more quickly diagnosing the cause of anomalies that occur during prelaunch processing. Reducing launch delays will be critical to the success of NASA's planned future missions that require in-orbit rendezvous. Third, it potentially reduces costs by reducing both launch delays and the number of people needed to monitor the prelaunch process. NASA is currently developing the Ares I launch vehicle to bring the Orion capsule and its crew of four astronauts to low-earth orbit on their way to the moon. Ares I-X will be the first unmanned test flight of Ares I. It is scheduled to launch on October 27, 2009. The Ares I-X Ground Diagnostic Prototype is a prototype ground diagnostic system that will provide anomaly detection, fault detection, fault isolation, and diagnostics for the Ares I-X first-stage thrust vector control (TVC) and for the associated ground hydraulics while it is in the Vehicle Assembly Building (VAB) at John F. Kennedy Space Center (KSC) and on the launch pad. It will serve as a prototype for a future operational ground diagnostic system for Ares I. The prototype combines three existing diagnostic tools. The first tool, TEAMS (Testability Engineering and Maintenance System), is a model-based tool that is commercially produced by Qualtech Systems, Inc. It uses a qualitative model of failure propagation to perform fault isolation and diagnostics. We adapted an existing TEAMS model of the TVC to use for diagnostics and developed a TEAMS model of the ground hydraulics. The second tool, Spacecraft Health Inference Engine (SHINE), is a rule-based expert system developed at the NASA Jet Propulsion Laboratory. We developed SHINE rules for fault detection and mode identification. The prototype uses the outputs of SHINE as inputs to TEAMS. The third tool, the Inductive Monitoring System (IMS), is an anomaly detection tool developed at NASA Ames Research Center and is currently used to monitor the International Space Station Control Moment Gyroscopes. IMS automatically "learns" a model of historical nominal data in the form of a set of clusters and signals an alarm when new data fails to match this model. IMS offers the potential to detect faults that have not been modeled. The three tools have been integrated and deployed to Hangar AE at KSC where they interface with live data from the Ares I-X vehicle and from the ground hydraulics. The outputs of the tools are displayed on a console in Hangar AE, one of the locations from which the Ares I-X launch will be monitored. The full paper will describe how the prototype performed before the launch. It will include an analysis of the prototype's accuracy, including false-positive rates, false-negative rates, and receiver operating characteristics (ROC) curves. It will also include a description of the prototype's computational requirements, including CPU usage, main memory usage, and disk usage. If the prototype detects any faults during the prelaunch period then the paper will include a description of those faults. Similarly, if the prototype has any false alarms then the paper will describe them and will attempt to explain their causes.
ERIC Educational Resources Information Center
Smith, Dorothy Veronica
2011-01-01
The past 20 years or so have seen ongoing concern for the nature of science education in the Anglophone developed world. A particular focus of this concern has been the need to find new ways to frame science curricula that will engage students, yet it is proving difficult to achieve this goal. In this article I argue that the impact on science…
Making Fuel While the Sun Shines.
Olzap, Nesrin; Sattler, Christian; Klausner, James F.; ...
2014-10-01
Recent advances in the production of photovoltaic panels have driven down the cost of solar power. Estimates for the levelized cost of electricity from PV range from 10 to 30 cents per kWh. And though this is still higher than the cost of generation from a newly built coal-fired thermal power station, solar power could be the cheapest electricity available in some areas within a few years, according to data from the Energy Information Agency.
21st Summer Farmers’ Market Boasts Quality Goods and Great People | Poster
NCI at Frederick’s 21st summer farmers’ market has officially begun, and this year’s vendors invite all employees to visit, browse their wares, and learn about the benefits of consuming all-natural products. The market is held every Tuesday until October 16 from 10:30 a.m. to 1:00 p.m. outside of Building 549—rain, shine, or, in the case of the most recent Tuesday, snow.
Shining a Light on Black Holes in Keratinocytes.
Bowman, Shanna L; Marks, Michael S
2018-03-01
The mechanisms by which melanins are transferred from melanocytes and stored within keratinocytes to generate skin pigmentation are hotly debated. Correia et al. and Hurbain et al. provide evidence that melanin cores of melanosomes are secreted from melanocytes and taken up and stored within non-degradative membranous organelles in keratinocytes in the basal epidermis of human skin. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.
Problem-solving test: Southwestern blotting.
Szeberényi, József
2014-01-01
Terms to be familiar with before you start to solve the test: Southern blotting, Western blotting, restriction endonucleases, agarose gel electrophoresis, nitrocellulose filter, molecular hybridization, polyacrylamide gel electrophoresis, proto-oncogene, c-abl, Src-homology domains, tyrosine protein kinase, nuclear localization signal, cDNA, deletion mutants, expression plasmid, transfection, RNA polymerase II, promoter, Shine-Dalgarno sequence, polyadenylation element, affinity chromatography, Northern blotting, immunoprecipitation, sodium dodecylsulfate, autoradiography, tandem repeats. Copyright © 2014 The International Union of Biochemistry and Molecular Biology.
Defect-induced ferromagnetism in ZnO nanoparticles prepared by mechanical milling
NASA Astrophysics Data System (ADS)
Phan, The-Long; Zhang, Y. D.; Yang, D. S.; Nghia, N. X.; Thanh, T. D.; Yu, S. C.
2013-02-01
Though ZnO is known as a diamagnetic material, recent studies have revealed that its nanostructures can be ferromagnetic (FM). The FM origin has been ascribed to intrinsic defects. This work shines light on an alternate method based on mechanical milling to induce defect-related ferromagnetism in ZnO nanoparticles (NPs) from initial diamagnetic ZnO powders. Our idea is motivated by the fact that mechanical milling introduces more defects to a ground material. We point out that the FM order increases with increasing the density of defects in ZnO NPs. The experimental results obtained from analyzing X-ray absorption, electron spin resonance, and Raman scattering spectra demonstrate that the ferromagnetism in ZnO NPs is due to intrinsic defects mainly related to oxygen and zinc vacancies. Among these, zinc vacancies play a decisive role in introducing a high FM order in ZnO NPs.
The Key Factors Analysis of Palisades Temperature in Deep Open-pit Mine
NASA Astrophysics Data System (ADS)
Wang, Yuan; Du, Cuifeng; Jin, Wenbo; Wang, Puyu
2018-01-01
In order to study the key factors of palisades temperature field in a deep open-pit mine in the natural environment, the influence of natural factors on the palisades temperature in a deep open-pit mine were analysed based on the principle of heat transfer. Four typical places with different ways of solar radiation were selected to carry out the field test. The results show that solar radiation, atmospheric temperature, and wind speed are three main factors affecting the temperature of palisades and that the direct sunlight plays a leading role. The time period of the sun shining directly on the shady slope of the palisades is short because of blocking effect, whose temperature changes in a smaller scale. At the same time, the sun slope of the palisades suffers from the solar radiation for a long time, whose temperature changes in a larger scale, and the variation is similar to the air temperature.
Katende, Godfrey; Donnelly, Mary
2016-05-01
In terms of disease burden, many low- and middle-income countries are currently experiencing a transition from infectious to chronic diseases. In Uganda, non-communicable diseases (NCDs) have increased significantly in recent years; this challenge is compounded by the healthcare worker shortage and the underfunded health system administration. Addressing the growing prevalence of NCDs requires evidence-based policies and strategies to reduce morbidity and mortality rates; however, the integration and evaluation of new policies and processes pose many challenges. Task-shifting is the process whereby specific tasks are transferred to health workers with less training and fewer qualifications. Successful implementation of a task-shifting policy requires appropriate skill training, clearly defined roles, adequate evaluation, an enhanced training capacity and sufficient health worker incentives. This article focuses on task-shifting policy as a potentially effective strategy to address the growing burden of NCDs on the Ugandan healthcare system.
Measurement of charge transfer potential barrier in pinned photodiode CMOS image sensors
NASA Astrophysics Data System (ADS)
Chen, Cao; Bing, Zhang; Junfeng, Wang; Longsheng, Wu
2016-05-01
The charge transfer potential barrier (CTPB) formed beneath the transfer gate causes a noticeable image lag issue in pinned photodiode (PPD) CMOS image sensors (CIS), and is difficult to measure straightforwardly since it is embedded inside the device. From an understanding of the CTPB formation mechanism, we report on an alternative method to feasibly measure the CTPB height by performing a linear extrapolation coupled with a horizontal left-shift on the sensor photoresponse curve under the steady-state illumination. The theoretical study was performed in detail on the principle of the proposed method. Application of the measurements on a prototype PPD-CIS chip with an array of 160 × 160 pixels is demonstrated. Such a method intends to shine new light on the guidance for the lag-free and high-speed sensors optimization based on PPD devices. Project supported by the National Defense Pre-Research Foundation of China (No. 51311050301095).
The electronic cigarette: a knight in shining armour or a Trojan horse?
Schluger, Neil W
2014-10-01
Electronic cigarettes have caused a sharp debate in the public health community, with some promoting them as a means of harm reduction for tobacco users and some taking a strong stand against them because of fear of renormalising smoking behaviour and interrupting tobacco control progress. People with mental health problems smoke at high rates and e-cigarettes seem a potentially attractive method of cessation in this population, and their use should be studied carefully.
Amnesty, Reconciliation and Reintegration: Conflict Termination in Counterinsurgency
2010-04-15
study and examine the conditions that allowed elements of AR2 to prevail. Having identified these conditions conducive to AR2 it will examine how ...26 In the case of Sierra Leone, the process of DDR was the result of a peace agreement, not a precursor to it. In the next example, I will show how ...ideology and violence perpetrated by the Shining Path movement and how the oppressive and reactionary nature of the government’s response undermined
Economic Renewal: A Grand Strategy for the United States
2010-03-24
Middle State Association of Colleges and Schools, 3624 Market Street, Philadelphia, PA 19104, (215) 662-5606. The Commission on Higher Education is...developing nations find free market capitalism less attractive. The U.S. should adopt a grand strategy of “economic renewal” to maintain its economic power...empire. Changes led by the U.S. are essential for this country to maintain its power as well as to shine as a beacon of free market and democratic
NASA Technical Reports Server (NTRS)
Brazel, J. P.; Kennedy, B. S.
1974-01-01
The materials studied are described along with the apparatus and the experimental techniques employed. The results of the measurements involving two REI Silica materials and a Mod 1 B REI Mullite are listed in a table. Measurements were conducted at unusually high temperature differences to detect 'shine-through' radiation transparency. Photographs are presented of the high-temperature guarded hot plate assembly.
2016-06-05
have attended and made presen- tations at the annual APS Division of Plasma Physics Meeting, the bi-annual High Energy Laboratory Astrophysics meeting...the AFOSR Space Science Pro- gram Review, the SHINE solar physics meeting, the International Astrophysics Conference, and the workshop “Complex plasma...tor k and Resolving Space-time Ambiguity. GR-Space Physics . submitted. Bellan, P. M., Zhai, X., Chai, K. B., & Ha, B. N. 2015. Complex astrophysical
ERIC Educational Resources Information Center
Budden, Michael Craig; Budden, Connie Browning
2007-01-01
University administrators can take a cue from pilots. Pilots regularly face decision situations where much lies in the balance. So it is with university administrators. The department, college or university itself can be compared to an aircraft. In flight, there are times when the sun shines and winds are favorable: a comfortable flight results…
Graphene in biomedicine: opportunities and challenges.
Feng, Liangzhu; Liu, Zhuang
2011-02-01
Graphene, whose discovery won the 2010 Nobel Prize in physics, has been a shining star in the material science in the past few years. Owing to its interesting electrical, optical, mechanical and chemical properties, graphene has found potential applications in a wide range of areas, including biomedicine. In this article, we will summarize the latest progress of using graphene for various biomedical applications, including drug delivery, cancer therapies and biosensing, and discuss the opportunities and challenges in this emerging field.
Kingdom of Saudi Arabia: Intercultural Awareness and the Iowa Air National Guard Elf One.
1983-02-01
Dodge, Iowa, ANG, for assis- tance in preparing the Flight for its winter involvement with "Elf One." After I surveyed our resources, Brigadier General...1978. 0 Cottrell, Alvin J. The Persian Gulf: A General Survey . Baltimore, Johns Hopins Univers. Press. 1980. Helms, Christine Moss. The Cohesion of...have your favorite brand. Recommendat ions: Razor flair Cream Shoe shine equipment Comb Shampoo Sewing kit Bath soap Toothbrush Toothpaste Deoderant
JPRS Report, Science & Technology, USSR: Computers
1987-09-28
history anew, "Battle of 1917" would come to your service. If you wish to control the destinies of nations, play around with the third world war ...engineering world . The time has come to return to this profession the romantic halo that once clearly and suitably shined, but that has now been almost...at bringing all of the computer technology produced in the association up to world standards within this five-year-plan. The creative potential of
Lovern, Ed
2002-05-27
Though saddled with higher costs than other hospitals, teaching hospitals reap plump margins on Medicare. But that could change this fall. A volley of studies say a looming 15% cut in indirect medical education payments and disproportionate-share payments could threaten the financial viability of healthcare's crown jewels unless Congress reverses current law.
HST Observations of the Uranian Ring Plane Crossing: Early Results
NASA Astrophysics Data System (ADS)
Showalter, Mark R.; Lissauer, J. J.; French, R. G.; Hamilton, D. P.; Nicholson, P. D.; de Pater, I.
2007-10-01
Between early May and mid-August 2007, Earth was on the north side of the Uranian ring plane while the Sun was still shining on the rings’ southern face. This has provided an exceedingly rare opportunity to view the ring system via transmitted light. The ɛ ring, which typically out-shines every other component of the inner ring-moon system, has been rendered essentially invisible. We have been conducting regular imaging of the Uranian system throughout this period with the Wide Field/Planetary Camera on HST to address numerous scientific goals. (1) To search the inner Uranian system for the "shepherding” moons long believed to confine the narrow rings; (2) to study the packing density of the main rings via direct observations of their vertical thickness; (3) to search for the inner dust rings that appeared in a few Voyager images; (4) to determine the vertical thickness of the faint outer rings μ and ν (5) to obtain the most sensitive determinations of the outer rings’ colors and try to understand why ring ν is red but ring μ is blue; (6) to search for additional outer dust rings under optimal viewing geometry; and (7) to continue monitoring the seemingly chaotic orbital variations of the inner Uranian moons, particularly Mab. HST observations span mid-May to mid-September. We will present our initial results from this observing program.
Multicenter clinical trial on a permanent hair dye containing paratoluenediamine.
Foti, Caterina; Balato, Nicola; Cristaudo, Antonio; Patruno, Cataldo; Pigatto, Paolo; Ambrifi, Marina; Bufano, Tamara; Damiani, Giovanni; De Rocco, Mariagrazia; Diani, Marco; Napolitano, Maddalena; Romita, Paolo
2018-08-01
Adverse reactions to hair dyes are frequent and usually caused by sensitization to paraphenylenediamine (PPD). The aim of the study was to evaluate the tolerability of a PPD-free permanent hair dye (Shine On, BioNike, Milan, Italy) containing paratoluenediamine (PTD) in a group of subjects sensitized to PPD. The trial, which carried out at four dermatology centers, included subjects sensitized to PPD that turned out negative to patch testing to PTD. The subjects underwent to an open test consisting in the application of two hair dye colors of the product under examination. Finally, subjects who were negative upon the open test were offered to undergo the usage test with the dye, with dermatological evaluations carried out 48 and 96 hours after product application. Sixty subjects were enrolled. They underwent the open test with two shades of dyes: "color 1 - black," the dye color with the highest concentration of color intermediates, and "color 7.3 - golden blonde," the dye color with the highest number of chemically different color intermediates. No reactions occurred with "color 7.3 - golden blonde," while 3 cases (3 out of 60) showed erythema and edema reactions to color 1. The hair dye usage test was negative for all the 21 subjects that were enrolled. The hair dye evaluated in this study (Shine On, BioNike) can be a valid alternative for subjects sensitized to PPD.
NASA Technical Reports Server (NTRS)
2005-01-01
[figure removed for brevity, see original site] 'Mars-shine' Composite NASA's Mars Exploration Rover Spirit continues to take advantage of favorable solar power conditions to conduct occasional nighttime astronomical observations from the summit region of 'Husband Hill.' Spirit has been observing the martian moons Phobos and Deimos to learn more about their orbits and surface properties. This has included observing eclipses. On Earth, a solar eclipse occurs when the Moon's orbit takes it exactly between the Sun and Earth, casting parts of Earth into shadow. A lunar eclipse occurs when the Earth is exactly between the Sun and the Moon, casting the Moon into shadow and often giving it a ghostly orange-reddish color. This color is created by sunlight reflected through Earth's atmosphere into the shadowed region. The primary difference between terrestrial and martian eclipses is that Mars' moons are too small to completely block the Sun from view during solar eclipses. Recently, Spirit observed a 'lunar' eclipse on Mars. Phobos, the larger of the two martian moons, was photographed while slipping into the shadow of Mars. Jim Bell, the astronomer in charge of the rover's panoramic camera (Pancam), suggested calling it a 'Phobal' eclipse rather than a lunar eclipse as a way of identifying which of the dozens of moons in our solar system was being cast into shadow. With the help of the Jet Propulsion Laboratory's navigation team, the Pancam team planned instructions to Spirit for acquiring the views shown here of Phobos as it entered into a lunar eclipse on the evening of the rover's 639th martian day, or sol (Oct. 20, 2005) on Mars. This image is a time-lapse composite of eight Pancam images of Phobos moving across the martian sky. The entire eclipse lasted more than 26 minutes, but Spirit was able to observe only in the first 15 minutes. During the time closest to the shadow crossing, Spirit's cameras were programmed to take images every 10 seconds. In the first three images, Phobos was in sunlight, moving toward the upper right. After a 100-second delay while Spirit's computer processed the first three images, the rover then took the fourth image, showing Phobos just starting to enter the darkness of the martian shadow. At that point, an observer sitting on Phobos and looking back toward the Sun would have seen a spectacular sunset! In the fifth image, Phobos appeared like a crescent, almost completely shrouded in darkness. In the last three images, Phobos had slipped entirely into the shadow of Mars. However, as with our own Moon during lunar eclipses on Earth, it was not entirely dark. The small amount of light still visible from Phobos is a kind of 'Mars-shine' -- sunlight reflected through Mars' atmosphere and into the shadowed region. Rover scientists took some images later in the sequence to try to figure out if this 'Mars-shine' made Phobos colorful while in eclipse, but they'll need more time to complete the analysis because the signal levels are so low. Meanwhile, they will use the information on the timing of the eclipse to refine the orbital path of Phobos. The precise position of Phobos will be important to any future spacecraft taking detailed pictures of the moon or landing on its surface. In the near future it might be possible for one of the rovers to take images of a 'Deimal' eclipse to learn more about Mars' other enigmatic satellite, Deimos, as well.Products available from NREL`s Renewable Resource Data Center
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gardner, T.Q.; Rymes, M.
1995-10-01
The Renewable Resource Data Center (RReDC) has been developed at the National Renewable Energy Laboratory (NREL) under the Resource Assessment Program. Initial offerings are broadband solar irradiance data bases such as the Daily Statistics Files and Typical Meteorological Years from the 1961--1990 National Solar Radiation Data Base, the West Associates data gathered in the Southwest US from 1976 through 1980, the New NOAA Network that replaced SOLMET from 1977 through 1980, and the one-minute data from four universities under the SEMRTS program. Unique data sets are the thousands of measured solar spectra and measurements of the solar intensity in themore » circumsolar region. All these data are provided with their accompanying documentation and online help. Other products such as Shining On and Solar Radiation Data Manual for Flat-Plate and Concentrating Collectors are available in their entirety, as well as glossaries, bibliographies, maps, and other user helps. The Uniform Resource Locator (URL) address of the RReDC is ``http://rredc.nrel.gov.`` Users should have World Wide Web (WWW) browsing software (such as Mosaic), which supports Forms and the necessary browsing viewers.« less
Quan, Runai; Zhai, Yiwei; Wang, Mengmeng; Hou, Feiyan; Wang, Shaofeng; Xiang, Xiao; Liu, Tao; Zhang, Shougang; Dong, Ruifang
2016-01-01
Based on the second-order quantum interference between frequency entangled photons that are generated by parametric down conversion, a quantum strategic algorithm for synchronizing two spatially separated clocks has been recently presented. In the reference frame of a Hong-Ou-Mandel (HOM) interferometer, photon correlations are used to define simultaneous events. Once the HOM interferometer is balanced by use of an adjustable optical delay in one arm, arrival times of simulta- neously generated photons are recorded by each clock. The clock offset is determined by correlation measurement of the recorded arrival times. Utilizing this algorithm, we demonstrate a proof-of-principle experiment for synchronizing two clocks separated by 4 km fiber link. A minimum timing stability of 0.44 ps at averaging time of 16000 s is achieved with an absolute time accuracy of 73.2 ps. The timing stability is verified to be limited by the correlation measurement device and ideally can be better than 10 fs. Such results shine a light to the application of quantum clock synchronization in the real high-accuracy timing system. PMID:27452276
Bernardini, Simone; Johnston, Steve; West, Bradley; ...
2016-11-14
Metal impurities are known to hinder the performance of commercial Si-based solar cells by inducing bulk recombination, increasing leakage current, and causing direct shunting. Recently, a set of photoluminescence (PL) images of neighboring multicrystalline silicon wafers taken from a cell production line at different processing stages has been acquired. Both band-to-band PL and sub-bandgap PL (subPL) images showed various regions with different PL signal intensity. Interestingly, in several of these regions a reversal of the subPL intensity was observed right after the deposition of the antireflective coating. In this paper, we present the results of the synchrotron-based nano-X-ray fluorescence imagingmore » performed in areas characterized by the subPL reversal to evaluate the possible role of metal decoration in this uncommon behavior. Furthermore, the acquisition of a statistically meaningful set of data for samples taken at different stages of the solar cell manufacturing allows us to shine a light on the precipitation and rediffusion mechanisms of metal impurities at these grain boundaries.« less
From the Sierra to the Cities: The Urban Campaign of the Shining Path
1992-01-01
AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS( ES ) Rand Corporation,1776 Main Street...PO Box 2138,Santa Monica,CA,90407-2138 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS( ES ) 10...indeed turned out to be correct. See " Que pasa con Sendero Luminoso?" QueHacer, No. 29, June 1984, pp. 34-38. 4Richard Webb and Graciela Fernandez
Aduszkiewicz, A.; Ali, Y.; Andronov, E.; ...
2017-01-30
Results on two-particle ΔηΔΦ correlations in inelastic p + p interactions at 20, 31, 40, 80, and 158 GeV/c are presented. The measurements were performed using the large acceptance NA61/SHINE hadron spectrometer at the CERN Super Proton Synchrotron. The data show structures which can be attributed mainly to effects of resonance decays, momentum conservation, and quantum statistics. Furthermore, the results are compared with the Epos and UrQMD models.
1994-06-03
CGSC, Fort Leavenworth, KS, Dec. 1990 LAS FUERZAS ARMADAS DEL PERU Y LOS DERECHOS HUMANOS EN LA LUCHA CONTRA EL TERRORISMO (Not Dated), A Booklet...op- erations were countered by the DINCOTE (Direccion Nacional Contra el Terrorismo ), a special antiterrorist branch of the national police. They...branches of our Army could contribute to a joint and combined operation in Peru to defeat Shining Path ele - ments. In addition to this, the reader may
The discoveries of Neptune and Triton.
NASA Astrophysics Data System (ADS)
Moore, P.
The story of the tracking-down of Neptune has been told many times, but even today there are still discrepancies in the various accounts, to say nothing of conflicting opinions. To some people, John Couch Adams is a shining hero and George Biddell Airy a black villain; to others it is Le Verrier who is the hero, and Adams an unimportant member of the supporting cast. Of course, all this is absurd. In the author's view, the true discoverers of Neptune were Johann Gottfried Galle and Heinrich D'Arrest.
Moll, Friedrich H; Halling, Thorsten; Hansson, Nils; Fangerau, Heiner
2017-03-01
In 1902, the Berlin Jewish urologist James Israel was nominated for the Nobel Prize in physiology or medicine. Taking scholar, social, and political aspects into consideration, this biographical essay traces how James Israel gained a sound scientific reputation especially in kidney surgery within Imperial Germany and its antisemitic attitude and how he promoted urology to become a specialty in its own right.
JPRS Report, East Asia, Korea: Kulloja, No. 3, March 1988.
1989-08-03
published in Pyongyang.] Let the 40th Anniversary of the Republic Shine as a Great Festival of Victors [Editorial Bureau] 1 The Chuche Ideology Is a...as a Great Festival of Victors 41090019 Pyongyang KULLOJA in Korean No 3, Mar 88 pp 3-9 [Article by Editorial Bureau] [Text] The year 1988 is a...festival of victors , filled to overflowing with a stirring sense of gratitude and enthusiasm. The great leader Comrade Kim Il-song taught as follows
Brazilian keratin hair treatment: a review.
Weathersby, Courtney; McMichael, Amy
2013-06-01
Brazilian keratin treatments are widely available products that are used by women all over the world to straighten hair. Marketers of these products claim that the keratin treatments render naturally curly hair more manageable and frizz-free while enhancing color and shine, giving the hair a healthier appearance. Although widely used, there have been virtually no reports of adverse side effects. Unfortunately, many of the products that are applied by salon professionals contain formaldehyde or its derivatives and are being marketed as safe. © 2013 Wiley Periodicals, Inc.
2016 Summer Series - Elizabeth Nyamayaro - How to Create a Social Movement
2016-07-14
Political activism is a tool used to create change, shining light on areas needing to be revisited. Humanity is at its best when we focus on our similarities while celebrating and promoting our differences; it is key to our survival. At NASA Ames, workforce diversity results in innovation and risk reduction. In her presentation, Ms. Elizabeth Nyamayaro will use the HeForShe movement as an example of factors that drive a successful movement and discuss gender equality.
Brannon, Paul J.; Cowgill, Donald F.
1990-01-01
A laser-triggered vacuum switch has a material such as a alkali metal halide on the cathode electrode for thermally activated field emission of electrons and ions upon interaction with a laser beam, the material being in contact with the cathode with a surface facing the discharge gap. The material is preferably a mixture of KCl and Ti powders. The laser may either shine directly on the material, preferably through a hole in the anode, or be directed to the material over a fiber optic cable.
Photochemical cutting of fabrics
Piltch, Martin S.
1994-01-01
Apparatus for the cutting of garment patterns from one or more layers of fabric. A laser capable of producing laser light at an ultraviolet wavelength is utilized to shine light through a pattern, such as a holographic phase filter, and through a lens onto the one or more layers of fabric. The ultraviolet laser light causes rapid photochemical decomposition of the one or more layers of fabric, but only along the pattern. The balance of the fabric of the one or more layers of fabric is undamaged.
Breaking the Nation’s Oil Addiction: Is Ethanol the Cure?
2006-09-29
from Biomass: Potential Availability and Benefits (Jan 2005), available at http://www.ethanol-gec.org/information/herwickgmn.1-27-05.ppt 25 id 26 Sholnn...Yellow" in an effort to raise public awareness of the benefits of the alternative fuel, derived from a eighty-five percent ethanol and fifteen percent...Congress sat down with domestic automakers representing Ford, GM, and Chrysler to discuss E85 use and its benefits .43 Hence, shining the spotlight on ethanol
Designing Tomorrow: Bringing Our Own Chair… Leading the Conversations.
Beglinger, Joan Ellis
2016-12-01
A highly visible transition occurred earlier this year with the retirement of Pam Thompson, MS, RN, CENP, FAAN, from her role as CEO of the American Organization of Nurse Executives. Ms Thompson was always an advocate of promoting the voice of nursing. This month, the spotlight will shine on a team of nurse leaders who found their voice, got involved, and led the conversation. We will trace their journey as they analyzed their situation, applied the evidence, and used their seat at the table.
Insurgency in Peru, Retrospective Analysis of the Sendero Luminoso’s (Shining Path)
2008-01-01
revive the idea of the glory of the Inca Empire before its conquest by Spain. Mariategui depicts the Incas as a glowing portrait ofan ideal society... Empire and called for, to a time before Spanish col~:mialism corrupted society. The Sendero believed that the only way to renew the Inca past was through...that was primarily agrarian and prospered. He dismissed criticisms of the Inca state as despotic and argued that it was Inca communism. In his eye, the
Roth, Bryan L; Kroeze, Wesley K
2015-08-07
G-protein-coupled receptors (GPCRs) are frequent and fruitful targets for drug discovery and development, as well as being off-targets for the side effects of a variety of medications. Much of the druggable non-olfactory human GPCR-ome remains under-interrogated, and we present here various approaches that we and others have used to shine light into these previously dark corners of the human genome. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.
A method of measuring a molten metal liquid pool volume
Garcia, G.V.; Carlson, N.M., Donaldson, A.D.
1990-12-12
A method of measuring a molten metal liquid pool volume and in particular molten titanium liquid pools, including the steps of (a) generating an ultrasonic wave at the surface of the molten metal liquid pool, (b) shining a light on the surface of a molten metal liquid pool, (c) detecting a change in the frequency of light, (d) detecting an ultrasonic wave echo at the surface of the molten metal liquid pool, and (e) computing the volume of the molten metal liquid. 3 figs.
Method of measuring a liquid pool volume
Garcia, G.V.; Carlson, N.M.; Donaldson, A.D.
1991-03-19
A method of measuring a molten metal liquid pool volume and in particular molten titanium liquid pools is disclosed, including the steps of (a) generating an ultrasonic wave at the surface of the molten metal liquid pool, (b) shining a light on the surface of a molten metal liquid pool, (c) detecting a change in the frequency of light, (d) detecting an ultrasonic wave echo at the surface of the molten metal liquid pool, and (e) computing the volume of the molten metal liquid. 3 figures.
Method of measuring a liquid pool volume
Garcia, Gabe V.; Carlson, Nancy M.; Donaldson, Alan D.
1991-01-01
A method of measuring a molten metal liquid pool volume and in particular molten titanium liquid pools, including the steps of (a) generating an ultrasonic wave at the surface of the molten metal liquid pool, (b) shining a light on the surface of a molten metal liquid pool, (c) detecting a change in the frequency of light, (d) detecting an ultrasonic wave echo at the surface of the molten metal liquid pool, and (e) computing the volume of the molten metal liquid.
The Peruvian Government’s Counterinsurgency Efforts to Defeat the Sendero Luminoso (Shining Path)
1993-06-04
tenure. Hacienda society was organized around the landowner, the sharecropper, and the peasant. The sharecropper, or yanacona, a Quechua term meaning...South America. hone of the Inca Empire. Cuzco, situated near Arequipa in a basin at 11.066 feet served as the Inca capital. In the Quechua language...among the inhabitants of the region. Ethnicity is defined in the region by the language of the two main ethnic groups, Quechua and Aymara. Those who
The electronic cigarette: a knight in shining armour or a Trojan horse?†
Schluger, Neil W.
2014-01-01
Electronic cigarettes have caused a sharp debate in the public health community, with some promoting them as a means of harm reduction for tobacco users and some taking a strong stand against them because of fear of renormalising smoking behaviour and interrupting tobacco control progress. People with mental health problems smoke at high rates and e-cigarettes seem a potentially attractive method of cessation in this population, and their use should be studied carefully. PMID:25285216
Strong Photoassociation in Ultracold Fermions
NASA Astrophysics Data System (ADS)
Jing, Li; Jamison, Alan; Rvachov, Timur; Ebadi, Sepher; Son, Hyungmok; Jiang, Yijun; Zwierlein, Martin; Ketterle, Wolfgang
2016-05-01
Despite many studies there are still open questions about strong photoassociation in ultracold gases. Photoassociation occurs only at short range and thus can be used as a tool to probe and control the two-body correlation function in an interacting many-body system and to engineer Hamiltonians using dissipation. We propose the possibility to slow down decoherence by photoassociation through the quantum Zeno effect. This can realized by shining strong photoassociation light on the superposition of the lowest two hyperfine states of Lithium 6. NSF, ARO-MURI, Samsung, NSERC.
Brannon, P.J.; Cowgill, D.F.
1990-12-18
A laser-triggered vacuum switch has a material such as a alkali metal halide on the cathode electrode for thermally activated field emission of electrons and ions upon interaction with a laser beam, the material being in contact with the cathode with a surface facing the discharge gap. The material is preferably a mixture of KCl and Ti powders. The laser may either shine directly on the material, preferably through a hole in the anode, or be directed to the material over a fiber optic cable. 10 figs.
Conceptualizing Astronomical Distances for Urban Populations
NASA Astrophysics Data System (ADS)
Popinchalk, Mark; Olson, Kristen; Ingber, Jenny; O'Brien, Mariel
2017-01-01
Students living in urban environments may have a washed-out night sky, but their enthusiasm for astronomy can still shine bright. As an educator, it can sometimes be a challenge to see the opportunities afforded by city living to the teaching of astronomy; however, several benefits can be identified. For example, the intrinsic understanding children have of the distances and scales involved in their everyday life is enhanced when they live in a regimented urban structure. This existing understanding of scale is critical to building a foundation for later conceptualizing of the universe.Leveraging the assets of New York City and the resources found in the American Museum of Natural History, The Science and Nature Program offers students (PreK through 8th grade) robust science learning experiences. To address concepts important for studying astronomy, we present a novel twist on the classic lesson “Earth as a Peppercorn,” by scaling the solar system to the size of New York City. Using local landmarks and their distance in relation to the Museum to represent the planets, students can use their prior knowledge of their surroundings to appreciate the impressive scale of our neighborhood in space in the context of their own neighborhoods. We correlate the activity with NGSS standards, present preliminary feedback on it’s success, and discuss the opportunities to apply a similar model lesson to other astronomical systems.
Exp 38 Patch Design - decal file allpath Replacement Pantones 4-
2013-04-30
ISS038-S-001 (April 2013) --- As the International Space Station (ISS) has become a stepping stone to future space exploration, the Expedition 38 mission patch design paints a visual roadmap of exploration beyond low Earth orbit, most prominently represented by the design?s flowing Expedition 38 mission numbers that wrap around Earth, the moon and Mars. Just as the sun is a guiding light in the galaxy, the ISS illuminates the bottom of the design as it is a shining beacon of the advancement of science, knowledge, and technology carried out aboard the Space Station. To visually capture the idea of the ISS being a foundation for infinite discovery, the space station?s iconic solar arrays span upwards, providing the number 38 and its exploration roadmap a symbolic pedestal to rest on. Finally, the overall use of red, white, and blue in the design acknowledges the flags of the countries of origin for Expedition 38?s crew ? the United States, Russia, and Japan. The NASA insignia design for space shuttle flights is reserved for use by the astronauts and for other official use as the NASA Administrator may authorize. Public availability has been approved only in the forms of illustrations by the various news media. When and if there is any change in this policy, which is not anticipated, the change will be publicly announced. Photo credit: NASA
Hubble Sees a Galactic Sunflower
2017-12-08
The arrangement of the spiral arms in the galaxy Messier 63, seen here in an image from the NASA/ESA Hubble Space Telescope, recall the pattern at the center of a sunflower. So the nickname for this cosmic object — the Sunflower Galaxy — is no coincidence. Discovered by Pierre Mechain in 1779, the galaxy later made it as the 63rd entry into fellow French astronomer Charles Messier’s famous catalogue, published in 1781. The two astronomers spotted the Sunflower Galaxy’s glow in the small, northern constellation Canes Venatici (the Hunting Dogs). We now know this galaxy is about 27 million light-years away and belongs to the M51 Group — a group of galaxies, named after its brightest member, Messier 51, another spiral-shaped galaxy dubbed the Whirlpool Galaxy. Galactic arms, sunflowers and whirlpools are only a few examples of nature’s apparent preference for spirals. For galaxies like Messier 63 the winding arms shine bright because of the presence of recently formed, blue–white giant stars and clusters, readily seen in this Hubble image. Image credit: ESA/Hubble & NASA NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
The five-box method: The "four-box method" for the Catholic physician.
Marugg, Lindsey; Atkinson, Marie-Noelle; Fernandes, Ashley
2014-11-01
The traditional ethical model of the "Four-Box Method" can be adapted to integrate the perspective of a Catholic physician. In an increasingly secularist environment, medical students and physicians are often asked to "leave religious beliefs at the door" and not consider the care and stewardship of our own morality and involvement as a provider. We reject this view. A patient's own religious and moral beliefs should be respected to the extent that they do not destroy our own; for us, the Catholic viewpoint can shine a light into dark corners and aid us in translating true things to patients of any religion. We analyzed a sample case in five different categories: medical indications, patient preferences, quality of life, contextual features, and the Catholic context. We explored how to methodically integrate the perspective of a Catholic physician into the analysis of this case to make the best decision for the patients. We felt that we were successfully able to integrate this perspective and create a "fifth box" based on the principles of Catholic social teaching. There were also points during the analysis that the perspective of the Catholic physician was integrated into the discussion of medical indications, proving to us that the "Catholic perspective" cannot be just put in one box either. The traditional ethical model of the "four-box method" can be adapted to integrate the perspective of a Catholic physician. In an increasingly secularist environment, medical students and physicians are often asked to "leave religious beliefs at the door" and not consider the care and stewardship of our own morality and involvement as a provider. We reject this view. A patient's own religious and moral beliefs should be respected to the extent that they do not destroy our own; for us, the Catholic viewpoint can shine a light into dark corners and aid us in translating true things to patients of any religion. By expanding to a "fifth box" of Catholic social teaching, the Catholic physician finds a way to methodically analyze an ethical scenario. This case study is an example of this type of "five-box" analysis.
Risk assessment during transport of radioactive materials through the Suez Canal
NASA Astrophysics Data System (ADS)
Sabek, M. G.; El-Shinawy, R. M. K.; Gomaa, M.
1997-03-01
In this paper a study for risk assessment of the impact of transporting radioactive materials, during the period 1986-1992, through the Suez Canal of Egypt is given. The code RADTRAN-IV was used for this study. The results of the code, for a normal case, show that the transportation of low activity materials such as uranium (U 3O 8) represent the main items that contribute significantly to the collective dose within the Suez Canal area (Port-Said, Ismailia and Suez). The values of the annual collective dose due to transportation of all radionuclide materials was found to be at a maximum in Suez town and is equal to 5.04 × 10 -8 Man-Sv for the whole populations. If we only consider the workder at the harbour (estimated to be 50 persons), the value of the annual collective dose is about 3.33 × 10 -4 Man-Sv. These values are less than the exemption value of 1 Man-Sv recommended by the IAEA. For the accident case, the following pathways are considered by the code: ground-shine, direct inhalation, inhalation of resuspended material and cloud-shine. The total values of the estimated risks for each radionuclide material are presented in table form and, in addition, health effects (genetic effects, GE, and latent cancer fatality), LCF) are discussed. The calculated values of the radiological risks are very low for the three towns, showing that no radiation-induced early deaths are to be expected.
Design of a probe for two-dimensional small angle detection
NASA Astrophysics Data System (ADS)
He, Haixia; Wang, Xuanze; Zhong, Yuning; Yang, Liangen; Cao, Hongduan
2008-10-01
A novel two-dimensional small angle probe is introduced, which is based on principle of auto-collimation and utilizes quadrant Si-photoelectric detector (QPD) as detection device. AC modulation, AC magnification and absolute value demodulation are incorporated to restrain the DC excursion caused by background light and noise etc and to improve the sensitivity and stability of angle detection. To ensure that while the laser is shining, the current signal (converted into voltage signal) of QPD also is linear to the AC modulation voltage, this paper adopted AC modulation signal (5400Hz) with a DC offset. AC magnification circuit with reasonable parameters is designed to inhibit DC drift and the impact of industrial frequency noise and to ensure good amplification to signal frequency at the same time. A piezoelectric-driven micro-angle generator is designed to demarcate the angle. The calibration data are input to single chip, and the measurement of angles can be shown in SMC1602A.
Washing when the sun is shining! How users interact with a household energy management system.
Kobus, Charlotte B A; Mugge, Ruth; Schoormans, Jan P L
2013-01-01
To make optimal use of sustainable energy, domestic electricity consumption should shift to match local supply conditions. Energy management systems (EMS) are a new sustainable technology that can help to disrupt consumers' habits concerning electricity consumption, whilst reinforcing desired behaviours. This research examined the factors that influence the likelihood that people will shift their electricity consumption to match sustainable supply. Twenty-one interviews were conducted with households who had used the EMS 'Smart Wash' for several months. The findings showed that the likelihood of behaviour change is influenced by a combination of the user's motivation, specific contextual factors and the design of the EMS. Based on these results, several recommendations are given for the future design of EMSs. Energy management systems (EMS) are a new technology that encourages people to shift electricity consumption to match local solar supply. Interviews among users of an EMS showed that the likelihood of behaviour change is influenced by the combination of the user's motivation, contextual factors and the EMS design.
On a path towards long-term sampling following the Deepwater Horizon: Initial insights
NASA Astrophysics Data System (ADS)
Reddy, C. M.
2012-12-01
During the past two decades in the United States, few areas contaminated from an oil spill have been revisited on the time scales from months to years. The lack of sampling is a missed opportunity to shine light on long-term processes, evaluate recovery, identify compounds most likely to persist, and apply new chemical and biological techniques. To address this issue, my laboratory has begun a land-based effort to collect oiled samples from the Gulf of Mexico beaches from the Deepwater Horizon disaster. Each sample is archived, analyzed, and available for others via an online repository. Detailed analysis of many of these samples has already been fruitful on determining the fate of the spilled oil, which will be discussed. This meeting is an ideal time to discuss strategies for long-term sampling and archiving. With support from the Gulf Research Initiative for the next nine years, the opportunities to use these samples will be frequent.
Reflecting on Space Benefits: A Shining Example
NASA Technical Reports Server (NTRS)
2006-01-01
NASA has long been known for having developed the thin, shiny reflective material used to insulate everything from the Hubble Space Telescope to hikers, from the Mars rovers to marathon runners, from computers to campers, from satellites to sun shields, and from rockets to residences. It is one of the simplest, yet most versatile spinoffs to come out of the Agency. The insulating material, a strong, plastic, vacuum-metallized film with a highly-efficient, infrared-reflective, vapor-deposited coating of aluminum, was created to be very lightweight in order to minimize weight impact on vehicle payload while also protecting spacecraft, equipment, and personnel from the extreme temperature fluctuations of space. It has been employed on virtually all manned and unmanned NASA missions. The shiny insulation which coated the base of the Apollo lunar landing vehicles is perhaps one of the most memorable early displays of this technology, and the bright, reflective honeycomb on the James Webb Space Telescope prototype is a testament to its lasting usefulness.
1393 Ring Bus at JPL: Description and Status
NASA Technical Reports Server (NTRS)
Wysocky, Terry R.
2007-01-01
Completed Ring Bus IC V&V Phase - Ring Bus Test Plan Completed for SIM Project - Applicable to Other Projects Implemented a Avionics Bus Based upon the IEEE 1393 Standard - Excellent Starting Point for a General Purpose High-Speed Spacecraft Bus - Designed to Meet SIM Requirements for - Real-time deterministic, distributed systems. - Control system requirements - Fault detection and recovery Other JPL Projects Considering Implementation F'light Software Ring Bus Driver Module Began in 2006, Continues Participating in Standard Revision. Search for Earth-like planets orbiting nearby stars and measure the masses and orbits of the planets it finds. Survey 2000 nearby stars for planetary systems to learn whether our Solar System is unusual, or typical. Make a new catalog of star position 100 times more accurate than current measurements. Learn how our galaxy formed and will evolve by studying the dynamics of its stars. Critically test models of exactly how stars shine, including exotic objects like black holes, neutron stars and white dwarfs.
Monte Carlo modelling of large scale NORM sources using MCNP.
Wallace, J D
2013-12-01
The representative Monte Carlo modelling of large scale planar sources (for comparison to external environmental radiation fields) is undertaken using substantial diameter and thin profile planar cylindrical sources. The relative impact of source extent, soil thickness and sky-shine are investigated to guide decisions relating to representative geometries. In addition, the impact of source to detector distance on the nature of the detector response, for a range of source sizes, has been investigated. These investigations, using an MCNP based model, indicate a soil cylinder of greater than 20 m diameter and of no less than 50 cm depth/height, combined with a 20 m deep sky section above the soil cylinder, are needed to representatively model the semi-infinite plane of uniformly distributed NORM sources. Initial investigation of the effect of detector placement indicate that smaller source sizes may be used to achieve a representative response at shorter source to detector distances. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.
Lo, Alex Y; Jim, C Y
2015-11-01
Tailored messages are instrumental to climate change communication. Information about the global threat can be 'localised' by demonstrating its linkage with local events. This research ascertains the relationship between climate change attitude and perception of local weather, based on a survey involving 800 Hong Kong citizens. Results indicate that concerns about climate change increase with expectations about the likelihood and impacts of local weather change. Climate change believers attend to all three types of adverse weather events, namely, temperature rises, tropical cyclones and prolonged rains. Climate scepticism, however, is not associated with expectation about prolonged rains. Differential spatial orientations are a possible reason. Global climate change is an unprecedented and distant threat, whereas local rain is a more familiar and localised weather event. Global climate change should be articulated in terms that respect local concerns. Localised framing may be particularly effective for engaging individuals holding positive views about climate change science. © The Author(s) 2014.
Interaction of surface plasmon polaritons and acoustic waves inside an acoustic cavity.
Khokhlov, Nikolai; Knyazev, Grigoriy; Glavin, Boris; Shtykov, Yakov; Romanov, Oleg; Belotelov, Vladimir
2017-09-15
In this Letter, we introduce an approach for manipulation of active plasmon polaritons via acoustic waves at sub-terahertz frequency range. The acoustic structures considered are designed as phononic Fabry-Perot microresonators where mirrors are presented with an acoustic superlattice and the structure's surface, and a plasmonic grating is placed on top of the acoustic cavity so formed. It provides phonon localization in the vicinity of the plasmonic grating at frequencies within the phononic stop band enhancing phonon-light interaction. We consider phonon excitation by shining a femtosecond laser pulse on the plasmonic grating. Appropriate theoretical model was used to describe the acoustic process caused by the pump laser pulse in the GaAs/AlAs-based acoustic cavity with a gold grating on top. Strongest modulation is achieved upon excitation of propagating surface plasmon polaritons and hybridization of propagating and localized plasmons. The relative changes in the optical reflectivity of the structure are more than an order of magnitude higher than for the structure without the plasmonic film.
All-Atom Simulations Reveal How Single-Point Mutations Promote Serpin Misfolding
NASA Astrophysics Data System (ADS)
Wang, Fang; Orioli, Simone; Ianeselli, Alan; Spagnolli, Giovanni; a Beccara, Silvio; Gershenson, Anne; Faccioli, Pietro; Wintrode, Patrick L.
2018-05-01
Protein misfolding is implicated in many diseases, including the serpinopathies. For the canonical inhibitory serpin {\\alpha}1-antitrypsin (A1AT), mutations can result in protein deficiencies leading to lung disease, and misfolded mutants can accumulate in hepatocytes leading to liver disease. Using all-atom simulations based on the recently developed Bias Functional algorithm we elucidate how wild-type A1AT folds and how the disease-associated S (Glu264Val) and Z (Glu342Lys) mutations lead to misfolding. The deleterious Z mutation disrupts folding at an early stage, while the relatively benign S mutant shows late stage minor misfolding. A number of suppressor mutations ameliorate the effects of the Z mutation and simulations on these mutants help to elucidate the relative roles of steric clashes and electrostatic interactions in Z misfolding. These results demonstrate a striking correlation between atomistic events and disease severity and shine light on the mechanisms driving chains away from their correct folding routes.
Everyday astronomy @ Sydney Observatory
NASA Astrophysics Data System (ADS)
Parello, S. L.
2008-06-01
Catering to a broad range of audiences, including many non-English speaking visitors, Sydney Observatory offers everything from school programmes to public sessions, day care activities to night observing, personal interactions to web-based outreach. With a history of nearly 150 years of watching the heavens, Sydney Observatory is now engaged in sharing the wonder with everybody in traditional and innovative ways. Along with time-honoured tours of the sky through two main telescopes, as well as a small planetarium, Sydney Observatory also boasts a 3D theatre, and offers programmes 363 days a year - rain or shine, day and night. Additionally, our website neversleeps, with a blog, YouTube videos, and night sky watching podcasts. And for good measure, a sprinkling of special events such as the incomparable Festival of the Stars, for which most of northern Sydney turns out their lights. Sydney Observatory is the oldest working observatory in Australia, and we're thrilled to be looking forward to our 150th Anniversary next year in anticipation of the International Year of Astronomy immediately thereafter.
NASA Technical Reports Server (NTRS)
2003-01-01
Emergency exit signs can be lifesavers, but only if they remain visible when people need them. All too often, power losses or poor visibility can render the signs ineffective. Luna Technologies International, Inc., of Kent, Washington, is shining new light on this safety issue. The company s LUNAplast(trademark) product line illuminates without the need for electricity, maintenance, or a power connection. LUNAplast, which benefited from tests conducted at Johnson Space Center, is so successful that NASA engineers selected it for the emergency exit pathway indicators on the International Space Station (ISS).
Interpretation of quantum yields exceeding unity in photoelectrochemical systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Szklarczyk, M.; Allen, R.E.
1986-10-20
In photoelectrochemical systems involving light shining on a semiconductor interfaced with an electrolyte, the quantum yield as a function of photon frequency ..nu.. is observed to exhibit a peak at h..nu..roughly-equal2E/sub g/, where E/sub g/ is the band gap of the semiconductor. The maximum in this peak is sometimes found to exceed unity. We provide an interpretation involving surface states and inelastic electron-electron scattering. The theory indicates that the effect should be observable for p-type semiconductors, but not n-type.
2007-04-02
KENNEDY SPACE CENTER, FLA. -- The American flag and the NASA logo shine in the morning sun on the side of the Vehicle Assembly Building after completion of their repainting. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The NASA logo, which is known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. Photo credit: NASA/Jim Grossmann
Ictal visual hallucinations due to frontal lobe epilepsy in a patient with bipolar disorder☆
Manfioli, Valeria; Saladini, Marina; Cagnin, Annachiara
2013-01-01
In ictal psychosis with complex visual hallucinations (VHs), widespread functional changes of cortical networks have been suggested. We describe the clinical and EEG findings of a patient with bipolar disorder who manifested complex VHs associated with intense emotional symptoms caused by frontal epileptic seizures. This description highlights the challenges of diagnosing the epileptic nature of new psychotic phenomena in patients with previous psychiatric disorders and shines light into the role of the frontal cortex in the genesis of complex VHs. PMID:25667849
Radiochromic film diagnostics for laser-driven ion beams
NASA Astrophysics Data System (ADS)
Kaufman, J.; Margarone, Daniele; Candiano, Giacomo; Kim, I. Jong; Jeong, Tae Moon; Pšikal, Jan; Romano, F.; Cirrone, P.; Scuderi, V.; Korn, Georg
2015-05-01
Radiochromic film (RCF) based multichannel diagnostics utilizes the concept of a stack detector comprised of alternating layers of RCFs and shielding aluminium layers. An algorithm based on SRIM simulations is used to correct the accumulated dose. Among the standard information that can be obtained is the maximum ion energy and to some extend the beam energy spectrum. The main area where this detector shines though is the geometrical characterization of the beam. Whereas other detectors such as Thomson parabola spectrometer or Faraday cups detect only a fraction of the outburst cone, the RCF stack placed right behind the target absorbs the whole beam. A complete 2D and to some extend 3D imprint of the ion beam allows us to determine parameters such as divergence or beam center shift with respect to the target normal. The obvious drawback of such diagnostics is its invasive character. But considering that only a few successful shots (2-3) are needed per one kind of target to perform the analysis, the drawbacks are acceptable. In this work, we present results obtained with the RCF diagnostics using both conventional accelerators and laser-driven ion beams during 2 experimental campaigns.
Hyperspectral imaging-based credit card verifier structure with adaptive learning.
Sumriddetchkajorn, Sarun; Intaravanne, Yuttana
2008-12-10
We propose and experimentally demonstrate a hyperspectral imaging-based optical structure for verifying a credit card. Our key idea comes from the fact that the fine detail of the embossed hologram stamped on the credit card is hard to duplicate, and therefore its key color features can be used for distinguishing between the real and counterfeit ones. As the embossed hologram is a diffractive optical element, we shine a number of broadband light sources one at a time, each at a different incident angle, on the embossed hologram of the credit card in such a way that different color spectra per incident angle beam are diffracted and separated in space. In this way, the center of mass of the histogram on each color plane is investigated by using a feed-forward backpropagation neural-network configuration. Our experimental demonstration using two off-the-shelf broadband white light emitting diodes, one digital camera, and a three-layer neural network can effectively identify 38 genuine and 109 counterfeit credit cards with false rejection rates of 5.26% and 0.92%, respectively. Key features include low cost, simplicity, no moving parts, no need of an additional decoding key, and adaptive learning.
Any Light Particle Search (ALPS)
NASA Astrophysics Data System (ADS)
Spector, Aaron; Any Light Particle Search (ALPS) Collaboration
2016-03-01
High power laser fields enabled by technologies developed for ground-based gravitational-wave observatories open up new opportunities for fundamental physics studies. One of these options is the search for axions and axion-like particles in a pure laboratory experiment. The axion is a solution to the strong CP-problem and a potential dark matter candidate. The axion has also been proposed as an additional channel to cool stars as well as a potential explanation for the TeV transparency problem. The German-US ALPS collaboration is setting up a light-shining-through-walls (LSW) experiment at DESY. LSW experiments are based on the simple idea that a high power laser field traversing a static magnetic field will transform partly into a relativistic axion field. This axion field will travel through an opaque wall into a second static magnetic field region where it turns partly back into an electromagnetic wave field with the same frequency as the laser. The ALPS collaboration is working towards a large scale LSW experiment at DESY in Hamburg, Germany. I will report on the status of the ALPS experiment. This work is supported by the Deutsche Forschungsgemeinschaft, PRISMA, the Helmholtz Association, the National Science Foundation and the Heising-Simons Foundation.
The Arts and Health Communication in Uganda: A Light Under the Table.
Sonke, Jill; Pesata, Virginia; Nakazibwe, Venny; Ssenyonjo, Jude; Lloyd, Robert; Espino, Danielle; Nieves, Mia; Khandakji, Samantha; Hahn, Phillip; Kerrigan, Maria
2018-04-01
This qualitative interview study brings the voices of 27 public health leaders, health communication experts, and artists who work in public health in Uganda together to articulate the principles and practices that make the country a shining example of effective, evidence-based use of the arts for health communication. The specific aim of the study was to identify best practices, theoretical foundations, and other factors that contribute to the success of arts-based health communication campaigns in Uganda. The study presents four primary themes related to use of the arts for health communication in Uganda: (1) the arts empower health communication; (2) the arts engage people emotionally; (3) effective programs are highly structured; and (4) professionalism is critical to program effectiveness. The findings suggest that the arts humanize, clarify, and empower health communication. The arts can attract attention and engage target populations, reduce hierarchical divisions and tensions that can challenge communication between health professionals and community members, make concepts clearer and more personally and culturally relevant, and communicate at an emotional level wherein concepts can be embodied and made actionable. The findings articulate why and how the arts are an effective means for health communication and can guide best practices.
Shining a light on high volume photocurable materials.
Palin, William M; Leprince, Julian G; Hadis, Mohammed A
2018-05-01
Spatial and temporal control is a key advantage for placement and rapid setting of light-activated resin composites. Conventionally, placement of multiple thin layers (<2mm) reduces the effect of light attenuation through highly filled and pigmented materials to increase polymerisation at the base of the restoration. However, and although light curing greater than 2mm thick layers is not an entirely new phenomenon, the desire amongst dental practitioners for even more rapid processing in deep cavities has led to the growing acceptance of so-called "bulk fill" (4-6mm thick) resin composites that are irradiated for 10-20s in daily clinical practice. The change in light transmission and attenuation during photopolymerisation are complex and related to path length, absorption properties of the photoinitiator and pigment, optical properties of the resin and filler and filler morphology. Understanding how light is transmitted through depth is therefore critical for ensuring optimal material properties at the base of thick increments. This article will briefly highlight the advent of current commercial materials that rationalise bulk filling techniques in dentistry, the relationship between light transmission and polymerisation and how optimal curing depths might be achieved. Copyright © 2018 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.
Bioluminescence imaging: a shining future for cardiac regeneration
Roura, Santiago; Gálvez-Montón, Carolina; Bayes-Genis, Antoni
2013-01-01
Advances in bioanalytical techniques have become crucial for both basic research and medical practice. One example, bioluminescence imaging (BLI), is based on the application of natural reactants with light-emitting capabilities (photoproteins and luciferases) isolated from a widespread group of organisms. The main challenges in cardiac regeneration remain unresolved, but a vast number of studies have harnessed BLI with the discovery of aequorin and green fluorescent proteins. First described in the luminous hydromedusan Aequorea victoria in the early 1960s, bioluminescent proteins have greatly contributed to the design and initiation of ongoing cell-based clinical trials on cardiovascular diseases. In conjunction with advances in reporter gene technology, BLI provides valuable information about the location and functional status of regenerative cells implanted into numerous animal models of disease. The purpose of this review was to present the great potential of BLI, among other existing imaging modalities, to refine effectiveness and underlying mechanisms of cardiac cell therapy. We recount the first discovery of natural primary compounds with light-emitting capabilities, and follow their applications to bioanalysis. We also illustrate insights and perspectives on BLI to illuminate current efforts in cardiac regeneration, where the future is bright. PMID:23402217
Gaggero, D; Grasso, D; Marinelli, A; Taoso, M; Urbano, A
2017-07-21
We present a novel interpretation of the γ-ray diffuse emission measured by Fermi-LAT and H.E.S.S. in the Galactic center (GC) region and the Galactic ridge (GR). In the first part we perform a data-driven analysis based on PASS8 Fermi-LAT data: We extend down to a few GeV the spectra measured by H.E.S.S. and infer the primary cosmic-ray (CR) radial distribution between 0.1 and 3 TeV. In the second part we adopt a CR transport model based on a position-dependent diffusion coefficient. Such behavior reproduces the radial dependence of the CR spectral index recently inferred from the Fermi-LAT observations. We find that the bulk of the GR emission can be naturally explained by the interaction of the diffuse steady-state Galactic CR sea with the gas present in the central molecular zone. Although we confirm the presence of a residual radial-dependent emission associated with a central source, the relevance of the large-scale diffuse component prevents to claim a solid evidence of GC pevatrons.
Ion Anisotropy and High-Energy Variability of Large Solar Particle Events: A Comparative Study
NASA Technical Reports Server (NTRS)
Tan, Lun C.; Reames, Donald V.; Ng, Chee K.
2008-01-01
We have made comparative studies of ion anisotropy and high-energy variability of solar energetic particle (SEP) events previously examined by the Solar, Heliospheric, and Interplanetary Environment (SHINE) Workshop campaign. We have found distinctly different characteristics of SEPs between two large "gradual" events having very similar solar progenitors (the 2002 April 21 and August 24 events). Since the scattering centers of SEPs are approximately frozen in the solar wind, we emphasize work in the solar-wind frame where SEPs tend to be isotropized, and small anisotropies are easier to detect. While in the August event no streaming reversal occurred, in the April event the field-aligned anisotropy of all heavy ions showed sign of streaming reversal. The difference in streaming reversal was consistent with the difference in the presence of the outer reflecting boundary. In the April event the magnetic mirror, which was located behind the interplanetary shock driven by the preceding coronal mass ejection (CME), could block the stream of SEPs, while in the August event SEPs escaped freely because of the absence of nearby boundary. The magnetic mirror was formed at the bottleneck of magnetic field lines draped around a flank of the preceding CME. In the previous SHINE event analysis the contrasting event durations and Fe/O ratios of the both events were explained as the interplay between shock geometry and seed population. Our new findings, however, indicate that event duration and time as well as spectral variation are also affected by the presence of a nearby reflecting boundary.
Lomsadze, Alexandre; Gemayel, Karl; Tang, Shiyuyun; Borodovsky, Mark
2018-05-17
In a conventional view of the prokaryotic genome organization, promoters precede operons and ribosome binding sites (RBSs) with Shine-Dalgarno consensus precede genes. However, recent experimental research suggesting a more diverse view motivated us to develop an algorithm with improved gene-finding accuracy. We describe GeneMarkS-2, an ab initio algorithm that uses a model derived by self-training for finding species-specific (native) genes, along with an array of precomputed "heuristic" models designed to identify harder-to-detect genes (likely horizontally transferred). Importantly, we designed GeneMarkS-2 to identify several types of distinct sequence patterns (signals) involved in gene expression control, among them the patterns characteristic for leaderless transcription as well as noncanonical RBS patterns. To assess the accuracy of GeneMarkS-2, we used genes validated by COG (Clusters of Orthologous Groups) annotation, proteomics experiments, and N-terminal protein sequencing. We observed that GeneMarkS-2 performed better on average in all accuracy measures when compared with the current state-of-the-art gene prediction tools. Furthermore, the screening of ∼5000 representative prokaryotic genomes made by GeneMarkS-2 predicted frequent leaderless transcription in both archaea and bacteria. We also observed that the RBS sites in some species with leadered transcription did not necessarily exhibit the Shine-Dalgarno consensus. The modeling of different types of sequence motifs regulating gene expression prompted a division of prokaryotic genomes into five categories with distinct sequence patterns around the gene starts. © 2018 Lomsadze et al.; Published by Cold Spring Harbor Laboratory Press.
Heliophysics in the United States of America
NASA Astrophysics Data System (ADS)
Smith, R. W.
2006-11-01
jmc@gi.alaska.edu The IHY program extends from the sun to the heliopause, or from the troposphere to the center of the sun, depending on your viewpoint. The US has cooperating observatories, CIPs and interested individuals willing to participate. On the other hand, there has been very little dedicated funding for the event even though NASA now claims a heliophysics program. Seen from the US viewpoint, this disappointment in funding is moderated by the fact that there are several existing programs that are well organized to collect data relevant to IHY needs. These include national programs such as CEDAR, GEM and SHINE as well as international coordinated groups such as CAWSES, eGY and IPY. Funding is adequate in each of these areas. Given that observational activity is funded and planned to happen, the most important remaining need is to communicate and demonstrate our original Universal Processes approach. Our task is to show how the Universal Processes approach adds important synthesis to the scientific process in programs that are happening. Hence we need to be present at workshops organized by CAWSES, CEDAR, GEM and SHINE to make our message relevant and stimulate studies focused on Universal Processes. Equally important is our emphasis on education and outreach. In the US we are planning special summer schools on IHY and special curriculum to be used in middle and high schools. We hope to produce a major documentary movie to air on television. In both outreach and in the arenas of professional science, our main aim is communication and demonstration of the new science of heliophysics.
Pei, Liying; Toyokawa, Satoshi; Kobayashi, Yasuki
2017-09-28
There is limited evidence on the relationship between labor factors and the decision to refrain from seeking medical services. This study aimed to examine how labor factors are related to medical service access among male and female workers in Tokyo and surrounding areas. We used data from 4,385 respondents to the survey in the Japanese Study on Stratification, Health, Income, and Neighborhood (J-SHINE), an ongoing epidemiologic household panel study. Surveys from 2010 to 2011 were analyzed. The outcome variable was whether or not an individual refrained from seeking medical services. Labor factors included employment type (permanent, temporary, or self-employed), company size (<100, 100-1,000, or >1,000 employees) and occupation type (white-collar, blue-collar). We included a total of 2,013 people after excluding those with missing data (analysis utilization: 45.9%). After adjusting covariates, we found that men working in small companies were more likely to refrain from seeking medical services than were those in medium or large companies (adjusted prevalence ratio [PR]: 1.19, 95% confidence interval [CI]: 1.04-1.37). Among women, however, those in self-employment (PR: 1.38, 95% CI: 1.08-1.77) and blue-collar employment (PR: 1.24, 95% CI: 1.04-1.47) were more likely to refrain than were those classified as permanent or white-collar workers. The relationship between labor factors and refraining from seeking medical services differed among men by company size, and among women by employment type and occupation type.
Oshima, Yoshimi; Shikata, Masahito; Koyama, Tomotsugu; Ohtsubo, Norihiro; Mitsuda, Nobutaka; Ohme-Takagi, Masaru
2013-01-01
The waxy plant cuticle protects cells from dehydration, repels pathogen attack, and prevents organ fusion during development. The transcription factor WAX INDUCER1/SHINE1 (WIN1/SHN1) regulates the biosynthesis of waxy substances in Arabidopsis thaliana. Here, we show that the MIXTA-like MYB transcription factors MYB106 and MYB16, which regulate epidermal cell morphology, also regulate cuticle development coordinately with WIN1/SHN1 in Arabidopsis and Torenia fournieri. Expression of a MYB106 chimeric repressor fusion (35S:MYB106-SRDX) and knockout/down of MYB106 and MYB16 induced cuticle deficiencies characterized by organ adhesion and reduction of epicuticular wax crystals and cutin nanoridges. A similar organ fusion phenotype was produced by expression of a WIN1/SHN1 chimeric repressor. Conversely, the dominant active form of MYB106 (35S:MYB106-VP16) induced ectopic production of cutin nanoridges and increased expression of WIN1/SHN1 and wax biosynthetic genes. Microarray experiments revealed that MYB106 and WIN1/SHN1 regulate similar sets of genes, predominantly those involved in wax and cutin biosynthesis. Furthermore, WIN1/SHN1 expression was induced by MYB106-VP16 and repressed by MYB106-SRDX. These results indicate that the regulatory cascade of MIXTA-like proteins and WIN1/SHN1 coordinately regulate cutin biosynthesis and wax accumulation. This study reveals an additional key aspect of MIXTA-like protein function and suggests a unique relationship between cuticle development and epidermal cell differentiation. PMID:23709630
Lapierre, Pascal; Mir, Mushtaq; Chase, Michael R.; Pyle, Margaret M.; Gawande, Richa; Ahmad, Rushdy; Sarracino, David A.; Ioerger, Thomas R.; Fortune, Sarah M.; Derbyshire, Keith M.; Wade, Joseph T.; Gray, Todd A.
2015-01-01
RNA-seq technologies have provided significant insight into the transcription networks of mycobacteria. However, such studies provide no definitive information on the translational landscape. Here, we use a combination of high-throughput transcriptome and proteome-profiling approaches to more rigorously understand protein expression in two mycobacterial species. RNA-seq and ribosome profiling in Mycobacterium smegmatis, and transcription start site (TSS) mapping and N-terminal peptide mass spectrometry in Mycobacterium tuberculosis, provide complementary, empirical datasets to examine the congruence of transcription and translation in the Mycobacterium genus. We find that nearly one-quarter of mycobacterial transcripts are leaderless, lacking a 5’ untranslated region (UTR) and Shine-Dalgarno ribosome-binding site. Our data indicate that leaderless translation is a major feature of mycobacterial genomes and is comparably robust to leadered initiation. Using translational reporters to systematically probe the cis-sequence requirements of leaderless translation initiation in mycobacteria, we find that an ATG or GTG at the mRNA 5’ end is both necessary and sufficient. This criterion, together with our ribosome occupancy data, suggests that mycobacteria encode hundreds of small, unannotated proteins at the 5’ ends of transcripts. The conservation of small proteins in both mycobacterial species tested suggests that some play important roles in mycobacterial physiology. Our translational-reporter system further indicates that mycobacterial leadered translation initiation requires a Shine Dalgarno site in the 5’ UTR and that ATG, GTG, TTG, and ATT codons can robustly initiate translation. Our combined approaches provide the first comprehensive view of mycobacterial gene structures and their non-canonical mechanisms of protein expression. PMID:26536359
Shell, Scarlet S; Wang, Jing; Lapierre, Pascal; Mir, Mushtaq; Chase, Michael R; Pyle, Margaret M; Gawande, Richa; Ahmad, Rushdy; Sarracino, David A; Ioerger, Thomas R; Fortune, Sarah M; Derbyshire, Keith M; Wade, Joseph T; Gray, Todd A
2015-11-01
RNA-seq technologies have provided significant insight into the transcription networks of mycobacteria. However, such studies provide no definitive information on the translational landscape. Here, we use a combination of high-throughput transcriptome and proteome-profiling approaches to more rigorously understand protein expression in two mycobacterial species. RNA-seq and ribosome profiling in Mycobacterium smegmatis, and transcription start site (TSS) mapping and N-terminal peptide mass spectrometry in Mycobacterium tuberculosis, provide complementary, empirical datasets to examine the congruence of transcription and translation in the Mycobacterium genus. We find that nearly one-quarter of mycobacterial transcripts are leaderless, lacking a 5' untranslated region (UTR) and Shine-Dalgarno ribosome-binding site. Our data indicate that leaderless translation is a major feature of mycobacterial genomes and is comparably robust to leadered initiation. Using translational reporters to systematically probe the cis-sequence requirements of leaderless translation initiation in mycobacteria, we find that an ATG or GTG at the mRNA 5' end is both necessary and sufficient. This criterion, together with our ribosome occupancy data, suggests that mycobacteria encode hundreds of small, unannotated proteins at the 5' ends of transcripts. The conservation of small proteins in both mycobacterial species tested suggests that some play important roles in mycobacterial physiology. Our translational-reporter system further indicates that mycobacterial leadered translation initiation requires a Shine Dalgarno site in the 5' UTR and that ATG, GTG, TTG, and ATT codons can robustly initiate translation. Our combined approaches provide the first comprehensive view of mycobacterial gene structures and their non-canonical mechanisms of protein expression.
Saha, Arpita; Oleshkevich, Elena; Vinas, Clara; Teixidor, Francesc
2017-12-01
Closely packed hollow spheres connected through pillars to a CdSe quantum dot (QD) core produce channels through which ions navigate. This particular structure is well represented by [CdSe@CarbOPH(O)]@Cl/[N(Caprylyl) 3 Me 1 ] indicating that in the channels between the canopy made by the carboranyl spheres (carboranylphosphinate, CarbOPH(O)) and the CdSe core exist chloride anions. Due to the close packing, the spheres produce openings. These are converted into gates because [N(Caprylyl) 3 Me 1 ] acts as a plug. The [CdSe@CarbOPH(O)]@Cl/assembly is negatively charged because the Cd positive charges are outnumbered by the negative charges due to the Se, the phosphinic acid and, very importantly, the trapped chloride anions, and this negative load is compensated by the cationic surfactant. Here, it is shown that this synergism produces an unprecedented phenomenon, namely, kinetic fluorescence switching. It is observed that the material shines brightly then loses its brightness and, upon the application of kinetic energy, shines back to the maximum power. This process continues for an extended period of time, up to half a year, at least. This new type of architecture in QDs is named as core-canopy QDs. In this case, this study demonstrates one property, the kinetic fluorescence switching, as a consequence of the trapping of Cl - in the QDs channels, but other properties can be envisaged with the judicious choice of the anions or even the pillar connecting the hollow sphere with the ground. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Instrumentation and Measurements for Electron Emission from Charged Insulators
NASA Technical Reports Server (NTRS)
Sim, Alec M.
2005-01-01
The electron was first discovered in 1898 by Sir John Joseph Thomson and has since been the subject of detailed study by nearly every scientific discipline. At nearly the same time Heinrich Rudolf Hertz conducted a series of experiments using cathode tubes, high potentials and ultraviolet light. When applying a large potential to a cathode he found that an arching event across the metal plates would occur. In addition, when shining an ultraviolet light on the metal he found that less potential was required to induce the spark. This result, taken together with other electrical phenomena brought about by the shining of light upon metal and was eventually termed the photoelectric effect. The work of Thomson and Hertz represent the beginning of electron emission studies and a body of ideas that pervade nearly all aspects of physics. In particular these ideas tell us a great deal about the nature of physical interactions within solids. In this thesis we will focus on the emission of electrons induced by an incident electron source over a range of energies, in which one can observe changes in emitted electron flux and energy distribution. In particular, when energetic particles impinge on a solid they can impart their energy, exciting electrons within the material. If this energy is sufficient to overcome surface energy barriers such as the work function, electron affinity or surface charge potential, electrons can escape from the material. The extent of electron emission from the material can be quantified as the ratio of incident particle flux to emitted particle flux, and is termed the electron yield.
Fallout Patterns from Operation HARDTACK, Phase 2
1960-05-01
8 mr from each source. For the other cases depicted in figures 4 and 5, the dose from shine was also about as large as or greater...5 D Control point building 2 8 miles, 4 C% or \\% ’ D ~ LU....,.L...,L ",... ... . .L to 5 ’ ol .05 .5 I 5 I0 50 100 TIME - HOURS 2,000 ś 1,000J...WELL AND BALLOON BURSTS). v fl7*l 4 : / ~ ~ 4 - 4 -- 12 10~ 0 8 - _ _ _ _ HAMILTON -50 FT TOWER Z Mercury - Warehouse 6 w U)U 0V 0 TIM - - FIUR 5 -
Growing Cutting-edge X-ray Optics
Conley, Ray
2018-03-02
Ever imagined that an Xbox controller could help open a window into a world spanning just one billionth of a meter? Brookhaven Lab's Ray Conley grows cutting-edge optics called multilayer Laue lenses (MLL) one atomic layer at a time to focus high-energy x-rays to within a single nanometer. To achieve this focusing feat, Ray uses a massive, custom-built atomic deposition device, an array of computers, and a trusty Xbox controller. These lenses will be deployed at the Lab's National Synchrotron Light Source II, due to begin shining super-bright light on pressing scientific puzzles in 2015.
2015-06-25
NASA's mission to push the limits of human exploration to beyond low earth orbit and to Mars will take humans farther than ever before. Achieving these goals requires collaborations and development of new technology. NASA Ames' expertise in re-entry technology is helping develop the architecture to achieve these goals. The Orion Heat Shield is an example of the materials and technology development needed to sustain heating rates far greater than missions returning from the International Space Station. Jeremy Vander Kam describes details working with this engineering and scientific marvel.
SpeedyTime_7-Minus_Eighty_Degrees_Laboratory_Freezer_for_ ISS
2017-08-23
SpeedyTime 7 – Minus Eighty Degrees Laboratory Freezer for ISS Cutting-edge science is on the daily menu on board the International Space Station, but where do the astronauts store their lab results before they’re shipped back to Earth? In one of a dozen large freezers, of course: in this SpeedyTime segment, Expedition 52 flight engineer Jack Fischer shines a light on the MELFI, Minus Eighty Degrees Laboratory Freezer for ISS. _______________________________________ FOLLOW THE SPACE STATION! Twitter: https://twitter.com/Space_Station Facebook: https://www.facebook.com/ISS Instagram: https://instagram.com/iss/
First real-time detection of solar pp neutrinos by Borexino
NASA Astrophysics Data System (ADS)
Pallavicini, M.; Bellini, G.; Benziger, J.; Bick, D.; Bonfini, G.; Bravo, D.; Caccianiga, B.; Calaprice, F.; Caminata, A.; Cavalcante, P.; Chavarria, A.; Chepurnov, A.; D'Angelo, D.; Davini, S.; Derbin, A.; Empl, A.; Etenko, A.; Fomenko, K.; Franco, D.; Gabriele, F.; Galbiati, C.; Gazzana, S.; Ghiano, C.; Giammarchi, M.; Göger-Neff, M.; Goretti, A.; Gromov, M.; Hagner, C.; Hungerford, E.; Ianni, Al.; Ianni, An.; Kayser, M.; Kobychev, V.; Korablëv, D.; Korga, G.; Kryn, D.; Laubenstein, M.; Lehnert, B.; Lewke, T.; Litvinovich, E.; Lombardi, F.; Lombardi, P.; Ludhova, L.; Lukyanchenko, G.; Machulin, I.; Manecki, S.; Maneschg, W.; Marcocci, S.; Meindl, Q.; Meroni, E.; Meyer, M.; Miramonti, L.; Misiaszek, M.; Montuschi, M.; Mosteiro, P.; Muratova, V.; Oberauer, L.; Obolensky, M.; Ortica, F.; Otis, K.; Papp, L.; Perasso, L.; Pocar, A.; Ranucci, G.; Razeto, A.; Re, A.; Romani, A.; Rossi, N.; Saldanha, R.; Salvo, C.; Schönert, S.; Simgen, H.; Skorokhvatov, M.; Smirnov, O.; Sotnikov, A.; Sukhotin, S.; Suvorov, Y.; Tartaglia, R.; Testera, G.; Vignaud, D.; Vogelaar, R. B.; von Feilitzsch, F.; Wang, H.; Winter, J.; Wojcik, M.; Wurm, M.; Zaimidoroga, O.; Zavatarelli, S.; Zuber, K.; Zuzel, G.
2016-07-01
Solar neutrinos have been pivotal to the discovery of neutrino flavour oscillations and are a unique tool to probe the reactions that keep the Sun shine. Although most of solar neutrino components have been directly measured, the neutrinos emitted by the keystone pp reaction, in which two protons fuse to make a deuteron, have so far eluded direct detection. The Borexino experiment, an ultra-pure liquid scintillator detector running at the Laboratori Nazionali del Gran Sasso in Italy, has now filled the gap, providing the first direct real time measurement of pp neutrinos and of the solar neutrino luminosity.
Uranyl sulfate irradiations at the Van de Graaff: A means to combat uranyl peroxide precipitation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Youker, Amanda J.; Kalensky, Michael; Quigley, Kevin J.
As part of an effort to support SHINE Medical Technologies in developing a process to produce Mo-99 by neutron-induced fission, a series of irradiation experiments was performed with a 3 MeV Van de Graaff accelerator to generate high radiation doses in 0.5–2 mL uranyl sulfate solutions. The purpose was to determine what conditions result in uranyl peroxide precipitation and what can be done to prevent its formation. The effects of temperature, dose rate, uranium concentration, and the addition of known catalysts for the destruction of peroxide were determined.
Hydraulic flow visualization method and apparatus
Karidis, Peter G.
1984-01-01
An apparatus and method for visualizing liquid flow. Pulses of gas bubbles are introduced into a liquid flow stream and a strobe light is operated at a frequency related to the frequency of the gas pulses to shine on the bubbles as they pass through the liquid stream. The gas pulses pass through a probe body having a valve element, and a reciprocating valve stem passes through the probe body to operate the valve element. A stem actuating device comprises a slidable reciprocating member, operated by a crank arm. The actuated member is adjustable to adjust the amount of the valve opening during each pulse.
2017-08-21
It is spring in the Northern hemisphere when NASA's Mars Reconnaissance Orbiter took this image. Over the winter, snow and ice have inexorably covered the dunes. Unlike on Earth, this snow and ice is carbon dioxide, better known to us as dry ice. When the sun starts shining on it in the spring, the ice on the smooth surface of the dune cracks and escaping gas carries dark sand out from the dune below, often creating beautiful patterns. On the rough surface between the dunes, frost is trapped behind small sheltered ridges. https://photojournal.jpl.nasa.gov/catalog/PIA21882
2007-04-02
KENNEDY SPACE CENTER, FLA. -- The NASA logo shines in the morning sun on the side of the Vehicle Assembly Building after completion of its repainting. The logo, which is known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. The American flag was also painted on the side of the VAB. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. Photo credit: NASA/Jim Grossmann
NASA Astrophysics Data System (ADS)
Vanovac, B.; Wolfrum, E.; Denk, S. S.; Mink, F.; Laggner, F. M.; Birkenmeier, G.; Willensdorfer, M.; Viezzer, E.; Hoelzl, M.; Freethy, S. J.; Dunne, M. G.; Lessig, A.; Luhmann, N. C., Jr.; the ASDEX Upgrade Team; the EUROfusion MST1 Team
2018-04-01
Electron cyclotron emission imaging (ECEI) provides measurements of electron temperature (T e ) and its fluctuations (δT e ). However, when measuring at the plasma edge, in the steep gradient region, radiation transport effects must be taken into account. It is shown that due to these effects, the scrape-off layer region is not accessible to the ECEI measurements in steady state conditions and that the signal is dominated by the shine-through emission. Transient effects, such as filaments, can change the radiation transport locally, but cannot be distinguished from the shine-through. Local density measurements are essential for the correct interpretation of the electron cyclotron emission, since the density fluctuations influence the temperature measurements at the plasma edge. As an example, a low frequency 8 kHz mode, which causes 10%-15% fluctuations in the signal level of the ECEI, is analysed. The same mode has been measured with the lithium beam emission spectroscopy density diagnostic, and is very well correlated in time with high frequency magnetic fluctuations. With radiation transport modelling of the electron cyclotron radiation in the ECEI geometry, it is shown that the density contributes significantly to the radiation temperature (T rad) and the experimental observations have shown the amplitude modulation in both density and temperature measurements. The poloidal velocity of the low frequency mode measured by the ECEI is 3 km s-1. The calculated velocity of the high frequency mode measured with the magnetic pick-up coils is about 25 km s-1. Velocities are compared with the E × B background flow velocity and possible explanations for the origin of the low frequency mode are discussed.
Cost-effectiveness of SHINE: A Telephone Translation of the Diabetes Prevention Program.
Hollenbeak, Christopher S; Weinstock, Ruth S; Cibula, Donald; Delahanty, Linda M; Trief, Paula M
2016-01-01
The Support, Health Information, Nutrition, and Exercise (SHINE) trial recently showed that a telephone adaptation of the Diabetes Prevention Program (DPP) lifestyle intervention was effective in reducing weight among patients with metabolic syndrome. The aim of this study is to determine whether a conference call (CC) adaptation was cost effective relative to an individual call (IC) adaptation of the DPP lifestyle intervention in the primary care setting. We performed a stochastic cost-effectiveness analysis alongside a clinical trial comparing two telephone adaptations of the DPP lifestyle intervention. The primary outcomes were incremental cost-effectiveness ratios estimated for weight loss, body mass index (BMI), waist circumference, and quality-adjusted life years (QALYs). Costs were estimated from the perspective of society and included direct medical costs, indirect costs, and intervention costs. After one year, participants receiving the CC intervention accumulated fewer costs ($2,831 vs. $2,933) than the IC group, lost more weight (6.2 kg vs. 5.1 kg), had greater reduction in BMI (2.1 vs. 1.9), and had greater reduction in waist circumference (6.5 cm vs. 5.9 cm). However, participants in the CC group had fewer QALYs than those in the IC group (0.635 vs. 0.646). The incremental cost-effectiveness ratio for CC vs. IC was $9,250/QALY, with a 48% probability of being cost-effective at a willingness-to-pay of $100,000/QALY. CC delivery of the DPP was cost effective relative to IC delivery in the first year in terms of cost per clinical measure (weight lost, BMI, and waist circumference) but not in terms of cost per QALY, most likely because of the short time horizon.
Behavior Change Techniques Present in Wearable Activity Trackers: A Critical Analysis
Mercer, Kathryn; Li, Melissa; Giangregorio, Lora; Burns, Catherine
2016-01-01
Background Wearable activity trackers are promising as interventions that offer guidance and support for increasing physical activity and health-focused tracking. Most adults do not meet their recommended daily activity guidelines, and wearable fitness trackers are increasingly cited as having great potential to improve the physical activity levels of adults. Objective The objective of this study was to use the Coventry, Aberdeen, and London-Refined (CALO-RE) taxonomy to examine if the design of wearable activity trackers incorporates behavior change techniques (BCTs). A secondary objective was to critically analyze whether the BCTs present relate to known drivers of behavior change, such as self-efficacy, with the intention of extending applicability to older adults in addition to the overall population. Methods Wearing each device for a period of 1 week, two independent raters used CALO-RE taxonomy to code the BCTs of the seven wearable activity trackers available in Canada as of March 2014. These included Fitbit Flex, Misfit Shine, Withings Pulse, Jawbone UP24, Spark Activity Tracker by SparkPeople, Nike+ FuelBand SE, and Polar Loop. We calculated interrater reliability using Cohen's kappa. Results The average number of BCTs identified was 16.3/40. Withings Pulse had the highest number of BCTs and Misfit Shine had the lowest. Most techniques centered around self-monitoring and self-regulation, all of which have been associated with improved physical activity in older adults. Techniques related to planning and providing instructions were scarce. Conclusions Overall, wearable activity trackers contain several BCTs that have been shown to increase physical activity in older adults. Although more research and development must be done to fully understand the potential of wearables as health interventions, the current wearable trackers offer significant potential with regard to BCTs relevant to uptake by all populations, including older adults. PMID:27122452
Conserved small mRNA with an unique, extended Shine-Dalgarno sequence
Hahn, Julia; Migur, Anzhela; von Boeselager, Raphael Freiherr; Kubatova, Nina; Kubareva, Elena; Schwalbe, Harald
2017-01-01
ABSTRACT Up to now, very small protein-coding genes have remained unrecognized in sequenced genomes. We identified an mRNA of 165 nucleotides (nt), which is conserved in Bradyrhizobiaceae and encodes a polypeptide with 14 amino acid residues (aa). The small mRNA harboring a unique Shine-Dalgarno sequence (SD) with a length of 17 nt was localized predominantly in the ribosome-containing P100 fraction of Bradyrhizobium japonicum USDA 110. Strong interaction between the mRNA and 30S ribosomal subunits was demonstrated by their co-sedimentation in sucrose density gradient. Using translational fusions with egfp, we detected weak translation and found that it is impeded by both the extended SD and the GTG start codon (instead of ATG). Biophysical characterization (CD- and NMR-spectroscopy) showed that synthesized polypeptide remained unstructured in physiological puffer. Replacement of the start codon by a stop codon increased the stability of the transcript, strongly suggesting additional posttranscriptional regulation at the ribosome. Therefore, the small gene was named rreB (ribosome-regulated expression in Bradyrhizobiaceae). Assuming that the unique ribosome binding site (RBS) is a hallmark of rreB homologs or similarly regulated genes, we looked for similar putative RBS in bacterial genomes and detected regions with at least 16 nt complementarity to the 3′-end of 16S rRNA upstream of sORFs in Caulobacterales, Rhizobiales, Rhodobacterales and Rhodospirillales. In the Rhodobacter/Roseobacter lineage of α-proteobacteria the corresponding gene (rreR) is conserved and encodes an 18 aa protein. This shows how specific RBS features can be used to identify new genes with presumably similar control of expression at the RNA level. PMID:27834614
Behavior Change Techniques Present in Wearable Activity Trackers: A Critical Analysis.
Mercer, Kathryn; Li, Melissa; Giangregorio, Lora; Burns, Catherine; Grindrod, Kelly
2016-04-27
Wearable activity trackers are promising as interventions that offer guidance and support for increasing physical activity and health-focused tracking. Most adults do not meet their recommended daily activity guidelines, and wearable fitness trackers are increasingly cited as having great potential to improve the physical activity levels of adults. The objective of this study was to use the Coventry, Aberdeen, and London-Refined (CALO-RE) taxonomy to examine if the design of wearable activity trackers incorporates behavior change techniques (BCTs). A secondary objective was to critically analyze whether the BCTs present relate to known drivers of behavior change, such as self-efficacy, with the intention of extending applicability to older adults in addition to the overall population. Wearing each device for a period of 1 week, two independent raters used CALO-RE taxonomy to code the BCTs of the seven wearable activity trackers available in Canada as of March 2014. These included Fitbit Flex, Misfit Shine, Withings Pulse, Jawbone UP24, Spark Activity Tracker by SparkPeople, Nike+ FuelBand SE, and Polar Loop. We calculated interrater reliability using Cohen's kappa. The average number of BCTs identified was 16.3/40. Withings Pulse had the highest number of BCTs and Misfit Shine had the lowest. Most techniques centered around self-monitoring and self-regulation, all of which have been associated with improved physical activity in older adults. Techniques related to planning and providing instructions were scarce. Overall, wearable activity trackers contain several BCTs that have been shown to increase physical activity in older adults. Although more research and development must be done to fully understand the potential of wearables as health interventions, the current wearable trackers offer significant potential with regard to BCTs relevant to uptake by all populations, including older adults.
2010-06-16
ISS024-E-006136 (16 June 2010) --- Polar mesospheric clouds, illuminated by an orbital sunrise, are featured in this image photographed by an Expedition 24 crew member on the International Space Station. Polar mesospheric, or noctilucent (?night shining?), clouds are observed from both Earth?s surface and in orbit by crew members aboard the space station. They are called night-shining clouds as they are usually seen at twilight. Following the setting of the sun below the horizon and darkening of Earth?s surface, these high clouds are still briefly illuminated by sunlight. Occasionally the ISS orbital track becomes nearly parallel to Earth?s day/night terminator for a time, allowing polar mesospheric clouds to be visible to the crew at times other than the usual twilight due to the space station altitude. This unusual photograph shows polar mesospheric clouds illuminated by the rising, rather than setting, sun at center right. Low clouds on the horizon appear yellow and orange, while higher clouds and aerosols are illuminated a brilliant white. Polar mesospheric clouds appear as light blue ribbons extending across the top of the image. These clouds typically occur at high latitudes of both the Northern and Southern Hemispheres, and at fairly high altitudes of 76?85 kilometers (near the boundary between the mesosphere and thermosphere atmospheric layers). The ISS was located over the Greek island of Kos in the Aegean Sea (near the southwestern coastline of Turkey) when the image was taken at approximately midnight local time. The orbital complex was tracking northeastward, nearly parallel to the terminator, making it possible to observe an apparent ?sunrise? located almost due north. A similar unusual alignment of the ISS orbit track, terminator position, and seasonal position of Earth?s orbit around the sun allowed for striking imagery of polar mesospheric clouds over the Southern Hemisphere earlier this year.
Normal-mode selectivity in ultrafast Raman excitations in C60
NASA Astrophysics Data System (ADS)
Zhang, G. P.; George, Thomas F.
2006-01-01
Ultrafast Raman spectra are a powerful tool to probe vibrational excitations, but inherently they are not normal-mode specific. For a system as complicated as C60 , there is no general rule to target a specific mode. A detailed study presented here aims to investigate normal-mode selectivity in C60 by an ultrafast laser. To accurately measure mode excitation, we formally introduce the kinetic-energy-based normal-mode analysis which overcomes the difficulty with the strong lattice anharmonicity and relaxation. We first investigate the resonant excitation and find that mode selectivity is normally difficult to achieve. However, for off-resonant excitations, it is possible to selectively excite a few modes in C60 by properly choosing an optimal laser pulse duration, which agrees with previous experimental and theoretical findings. Going beyond the phenomenological explanation, our study shines new light on the origin of the optimal duration: The phase matching between the laser field and mode vibration determines which mode is strongly excited or suppressed. This finding is very robust and should be a useful guide for future experimental and theoretical studies in more complicated systems.
Normal mode selectivity in ultrafast Raman excitations in C60
NASA Astrophysics Data System (ADS)
Zhang, Guoping; George, Thomas F.
2006-05-01
Ultrafast Raman spectra are a powerful tool to probe vibrational excitations, but inherently they are not normal-mode specific. For a system as complicated as C60, there is no general rule to target a specific mode. A detailed study presented here aims to investigate normal mode selectivity in C60 by an ultrafast laser. To accurately measure mode excitation, we formally introduce the kinetic energy-based normal mode analysis which overcomes the difficulty with the strong lattice anharmonicity and relaxation. We first investigate the resonant excitation and find that mode selectivity is normally difficult to achieve. However, for off-resonant excitations, it is possible to selectively excite a few modes in C60 by properly choosing an optimal laser pulse duration, which agrees with previous experimental and theoretical findings. Going beyond the phenomenological explanation, our study shines new light on the origin of the optimal duration: The phase matching between laser field and mode vibration determines which mode is strongly excited or suppressed. This finding is very robust and may be a useful guide for future experimental and theoretical studies in more complicated systems.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Amato, I.
1989-01-01
The beauty of photosynthesis runs deep into its physicochemical details, many of which continue to elude scientific understanding. One of the big unsolved mysteries of photosynthesis is how the oxygen molecules are made, remarks David Mauzerall, a biophysicist at Rockefeller University in New York City. He and his colleagues, Ora Canaani and Shmuel Malkin, both biochemists at the Weizmann Institute of Science in Rehovot, Israel, are shining some light on this mystery. Using a technique called pulsed photoacoustic spectroscopy, the three researchers have eavesdropped on some of the intimate details of oxygen evolution. You can now hear the sound ofmore » oxygen coming out of the leaves, Mauzerall said in an interview. Mauzerall and co-workers reported their work last summer in the Proceedings of the National Academy of Sciences. Did he say, hear oxygen. As its name implies, photoacoustic spectroscopy is a sound-from-light technique. It is especially suited for getting spectra from samples like leaves that mess up the incident badly that even scattering or reflection-based spectroscopic methods usually can't reveal too much about the plant's chemical personality.« less
A credit card verifier structure using diffraction and spectroscopy concepts
NASA Astrophysics Data System (ADS)
Sumriddetchkajorn, Sarun; Intaravanne, Yuttana
2008-04-01
We propose and experimentally demonstrate an angle-multiplexing based optical structure for verifying a credit card. Our key idea comes from the fact that the fine detail of the embossed hologram stamped on the credit card is hard to duplicate and therefore its key color features can be used for distinguishing between the real and counterfeit ones. As the embossed hologram is a diffractive optical element, we choose to shine one at a time a number of broadband lightsources, each at different incident angle, on the embossed hologram of the credit card in such a way that different color spectra per incident angle beam is diffracted and separated in space. In this way, the number of pixels of each color plane is investigated. Then we apply a feed forward back propagation neural network configuration to separate the counterfeit credit card from the real one. Our experimental demonstration using two off-the-shelf broadband white light emitting diodes, one digital camera, a 3-layer neural network, and a notebook computer can identify all 69 counterfeit credit cards from eight real credit cards.
Gourdain, P-A
2017-05-01
In recent years, our understanding of high energy density plasmas has played an important role in improving inertial fusion confinement and in emerging new fields of physics, such as laboratory astrophysics. Every new idea required developing innovative experimental platforms at high power laser facilities, such as OMEGA or NIF. These facilities, designed to focus all their beams onto spherical targets or hohlraum windows, are now required to shine them on more complex targets. While the pointing on planar geometries is relatively straightforward, it becomes problematic for cylindrical targets or target with more complex geometries. This publication describes how the distribution of laser beams on a cylindrical target can be done simply by using a set of physical laws as a pointing procedure. The advantage of the method is threefold. First, it is straightforward, requiring no mathematical enterprise besides solving ordinary differential equations. Second, it will converge if a local optimum exists. Finally, it is computationally inexpensive. Experimental results show that this approach produces a geometrical beam distribution that yields cylindrically symmetric implosions.
1993-03-03
Inadequately understood statistics so often cloud both the argument of the researcher and the judgement of the reader. Norma Reid brings a refreshing clarity to a complex topic; she takes the mystification and mystique out of statistics. Her basic premiss that theory ought to be based on practical utility and relevance shines through her text and helps to make the subject accessible co clinicians who want to understand the underpinnings of their practice. Research methods, particularly qualitative approaches, are sketchily dealt with when compared with the wealth of detail on the mechanics of computing. Also, it is awkward to find methods and analysis not clearly separated in places (eg, Delphi studies), but ample references direct the reader to more expansive sources. Any attempt to steer the uninitiated through the minefields of computing is fraught with difficulties, and some will be disappointed to find one system used exclusively, but, perhaps, it serves as an illustration rather than a course to be slavishly followed.
Using Link Disconnection Entropy Disorder to Detect Fast Moving Nodes in MANETs.
Alvarez, Carlos F; Palafox, Luis E; Aguilar, Leocundo; Sanchez, Mauricio A; Martinez, Luis G
2016-01-01
Mobile ad-hoc networks (MANETs) are dynamic by nature; this dynamism comes from node mobility, traffic congestion, and other transmission conditions. Metrics to evaluate the effects of those conditions shine a light on node's behavior in an ad-hoc network, helping to identify the node or nodes with better conditions of connection. In this paper, we propose a relative index to evaluate a single node reliability, based on the link disconnection entropy disorder using neighboring nodes as reference. Link disconnection entropy disorder is best used to identify fast moving nodes or nodes with unstable communications, this without the need of specialized sensors such as GPS. Several scenarios were studied to verify the index, measuring the effects of Speed and traffic density on the link disconnection entropy disorder. Packet delivery ratio is associated to the metric detecting a strong relationship, enabling the use of the link disconnection entropy disorder to evaluate the stability of a node to communicate with other nodes. To expand the utilization of the link entropy disorder, we identified nodes with higher speeds in network simulations just by using the link entropy disorder.
PF120916 Piecki fireball and Reszel meteorite fall
NASA Astrophysics Data System (ADS)
Olech, A.; Żołądek, P.; Tymiński, Z.; Stolarz, M.; Wiśniewski, M.; Bęben, M.; Lewandowski, T.; Polak, K.; Raj, A.; Zaręba, P.
2017-06-01
On September 12, 2016, at 21:44:07 UT, a -9.2±0.5 mag fireball appeared over northeastern Poland. The precise orbit and atmospheric trajectory of the event are presented, based on the data collected by six video stations of the Polish Fireball Network (PFN). The PF120916 Piecki fireball entered the Earth's atmosphere with the velocity of 16.7±0.3 km/s and started to shine at a height of 81.9 ± 0.3 km. Clear deceleration started after first three seconds of the flight, and the terminal velocity of the meteor was only 5.0±0.3 km/s at a height of 26.0 ± 0.2 km. Such a low value of the terminal velocity indicates that fragments with the total mass of around 10-15 kg could survive the atmospheric passage and cause fall of the meteorites. The predicted area of possible meteorite impact is computed and it is located south of Reszel city at the Warmian-Masurian region. The impact area was extensively searched by experienced groups of meteorite hunters, but without any success.
Illuminating the chirality of Weyl fermions
NASA Astrophysics Data System (ADS)
Ma, Qiong; Xu, Su-Yang; Chan, Ching-Kit; Zhang, Cheng-Long; Chang, Guoqing; Lin, Hsin; Jia, Shuang; Lee, Patrick; Gedik, Nuh; Jarillo-Herrero, Pablo
In particle physics, Weyl fermions (WF) are elementary particles that travel at the speed of light and have a definite chirality. In condensed matter, it has been recently realized that WFs can arise as magnetic monopoles in the momentum space of a novel topological metal, the Weyl semimetal (WSM). Their chirality, given by the sign of the monopole charge, is the defining property of a WSM, since it directly serves as the topological number and gives rise to exotic properties such as Fermi arcs and the chiral anomaly. Moreover, the two chiralities, analogous to the two valleys in 2D materials, lead to a new degree of freedom in a 3D crystal, suggesting novel pathways to store and carry information. By shining circularly polarized light on the WSM TaAs, we illuminate the chirality of the WFs and achieve an electrical current that is highly controllable based on the WFs' chirality. Our results open up a wide range of new possibilities for experimentally studying and controlling the WFs and their associated quantum anomalies by optical and electrical means, which suggest the exciting prospect of ``Weyltronics''.
NASA Astrophysics Data System (ADS)
Gourdain, P.-A.
2017-05-01
In recent years, our understanding of high energy density plasmas has played an important role in improving inertial fusion confinement and in emerging new fields of physics, such as laboratory astrophysics. Every new idea required developing innovative experimental platforms at high power laser facilities, such as OMEGA or NIF. These facilities, designed to focus all their beams onto spherical targets or hohlraum windows, are now required to shine them on more complex targets. While the pointing on planar geometries is relatively straightforward, it becomes problematic for cylindrical targets or target with more complex geometries. This publication describes how the distribution of laser beams on a cylindrical target can be done simply by using a set of physical laws as a pointing procedure. The advantage of the method is threefold. First, it is straightforward, requiring no mathematical enterprise besides solving ordinary differential equations. Second, it will converge if a local optimum exists. Finally, it is computationally inexpensive. Experimental results show that this approach produces a geometrical beam distribution that yields cylindrically symmetric implosions.
Detection of explosives by differential hyperspectral imaging
NASA Astrophysics Data System (ADS)
Dubroca, Thierry; Brown, Gregory; Hummel, Rolf E.
2014-02-01
Our team has pioneered an explosives detection technique based on hyperspectral imaging of surfaces. Briefly, differential reflectometry (DR) shines ultraviolet (UV) and blue light on two close-by areas on a surface (for example, a piece of luggage on a moving conveyer belt). Upon reflection, the light is collected with a spectrometer combined with a charge coupled device (CCD) camera. A computer processes the data and produces in turn differential reflection spectra taken from these two adjacent areas on the surface. This differential technique is highly sensitive and provides spectroscopic data of materials, particularly of explosives. As an example, 2,4,6-trinitrotoluene displays strong and distinct features in differential reflectograms near 420 and 250 nm, that is, in the near-UV region. Similar, but distinctly different features are observed for other explosives. Finally, a custom algorithm classifies the collected spectral data and outputs an acoustic signal if a threat is detected. This paper presents the complete DR hyperspectral imager which we have designed and built from the hardware to the software, complete with an analysis of the device specifications.
Producing microbial polyhydroxyalkanoate (PHA) biopolyesters in a sustainable manner.
Koller, Martin; Maršálek, Lukáš; de Sousa Dias, Miguel Miranda; Braunegg, Gerhart
2017-07-25
Sustainable production of microbial polyhydroxyalkanoate (PHA) biopolyesters on a larger scale has to consider the "four magic e": economic, ethical, environmental, and engineering aspects. Moreover, sustainability of PHA production can be quantified by modern tools of Life Cycle Assessment. Economic issues are to a large extent affected by the applied production mode, downstream processing, and, most of all, by the selection of carbon-rich raw materials as feedstocks for PHA production by safe and naturally occurring wild type microorganisms. In order to comply with ethics, such raw materials should be used which do not interfere with human nutrition and animal feed supply chains, and shall be convertible towards accessible carbon feedstocks by simple methods of upstream processing. Examples were identified in carbon-rich waste materials from various industrial braches closely connected to food production. Therefore, the article shines a light on hetero-, mixo-, and autotrophic PHA production based on various industrial residues from different branches. Emphasis is devoted to the integration of PHA-production based on selected raw materials into the holistic patterns of sustainability; this encompasses the choice of new, powerful microbial production strains, non-hazardous, environmentally benign methods for PHA recovery, and reutilization of waste streams from the PHA production process itself. Copyright © 2016 Elsevier B.V. All rights reserved.
Shine on: Review of Laser- and Light-Based Therapies for the Treatment of Burn Scars
Hultman, C. Scott; Edkins, Renee E.; Lee, Clara N.; Calvert, Catherine T.; Cairns, Bruce A.
2012-01-01
Restoration of form and function after burn injury remains challenging, but emerging laser and pulsed light technologies now offer hope for patients with hypertrophic scars, which may be associated with persistent hyperemia, chronic folliculitis, intense pruritis, and neuropathic pain. In addition to impairing body image, these scars may limit functional recovery, compromise activities of daily living, and prevent return to work. Three different platforms are now poised to alter our reconstructive algorithm: (1) vascular-specific pulsed dye laser (PDL) to reduce hyperemia, (2) ablative fractional CO2 laser to improve texture and pliability of the burn scar, and (3) intense pulsed light (IPL) to correct burn scar dyschromia and alleviate chronic folliculitis. In this paper, we will provide an overview of our work in this area, which includes a systematic review, a retrospective analysis of our preliminary experience, and interim data from our on-going, prospective, before-after cohort trial. We will demonstrate that laser- and light-based therapies can be combined with each other safely to yield superior results, often at lower cost, by reducing the need for reconstructive surgery. Modulating the burn scar, through minimally invasive modalities, may replace conventional methods of burn scar excision and yield outcomes not previously possible or conceivable. PMID:22778719
Mahdy, M R C; Danesh, Md; Zhang, Tianhang; Ding, Weiqiang; Rivy, Hamim Mahmud; Chowdhury, Ariful Bari; Mehmood, M Q
2018-02-16
The stimulating connection between the reversal of near-field plasmonic binding force and the role of symmetry-breaking has not been investigated comprehensively in the literature. In this work, the symmetry of spherical plasmonic heterodimer-setup is broken forcefully by shining the light from a specific side of the set-up instead of impinging it from the top. We demonstrate that for the forced symmetry-broken spherical heterodimer-configurations: reversal of lateral and longitudinal near-field binding force follow completely distinct mechanisms. Interestingly, the reversal of longitudinal binding force can be easily controlled either by changing the direction of light propagation or by varying their relative orientation. This simple process of controlling binding force may open a novel generic way of optical manipulation even with the heterodimers of other shapes. Though it is commonly believed that the reversal of near-field plasmonic binding force should naturally occur for the presence of bonding and anti-bonding modes or at least for the Fano resonance (and plasmonic forces mostly arise from the surface force), our study based on Lorentz-force dynamics suggests notably opposite proposals for the aforementioned cases. Observations in this article can be very useful for improved sensors, particle clustering and aggregation.
The source of solar energy, ca. 1840-1910: From meteoric hypothesis to radioactive speculations
NASA Astrophysics Data System (ADS)
Kragh, Helge
2016-12-01
Why does the Sun shine? Today we know the answer to the question and we also know that earlier answers were quite wrong. The problem of the source of solar energy became an important part of physics and astronomy only with the emergence of the law of energy conservation in the 1840s. The first theory of solar heat based on the new law, due to J.R. Mayer, assumed the heat to be the result of meteors or asteroids falling into the Sun. A different and more successful version of gravitation-to-heat energy conversion was proposed by H. Helmholtz in 1854 and further developed by W. Thomson. For more than forty years the once so celebrated Helmholtz-Thomson contraction theory was accepted as the standard theory of solar heat despite its prediction of an age of the Sun of only 20 million years. In between the gradual demise of this theory and the radically different one based on nuclear processes there was a period in which radioactivity was considered a possible alternative to gravitational contraction. The essay discusses various pre-nuclear ideas of solar energy production, including the broader relevance of the question as it was conceived in the Victorian era.
De-demonizing the VRAEM: A Peruvian-Cocalero Area.
Ferreira, Francisco
2016-01-02
The valley of the rivers Apurímac, Ene, and Mantaro (VRAEM) is the main center of coca production in Peru. This is a jungle area located between southern highland regions, and is notorious for the presence of drug-trafficking and the last remnants of Shining Path guerrillas. As a result, it occupies a central place in security policies in Peru, and has been "demonized" in the national imaginary. This article explores the current situation, recent history, and most important collectives of the VRAEM, challenging stereotypes about it. The article is based on short-term fieldwork undertaken in the VRAEM in March 2008, and long-term research conducted in Ayacucho in 2008-2009; and it is contextualized in relation to the literature on coca producing areas and drug policies. The negative image of the VRAEM started in the context of the 1980s-1990s coca boom and Peruvian armed conflict. State policies in the area since then have been mainly based on militarization and repression, contributing to maintain that negative image, which differs of a complex and nuanced local reality. A coca eradication campaign started in 2014, bringing major changes. The negative image of the VRAEM is largely unfair, and has been mainly based on stereotypes and prejudices. This negative stereotyping contributes to justify and maintain inefficient and pernicious state policies in the area, and to criminalize local people. There is an urgent need for fieldwork-based studies in the area to counteract those negative stereotypes and monitor current events.
Climate Change: A Multidisciplinary Approach, Second Edition
NASA Astrophysics Data System (ADS)
Kirk-Davidoff, Daniel
2008-07-01
William Burroughs, who died in November 2007, was a wonderfully clear and evocative writer. Chapter 3 of his last work, Climate Change: A Multidisciplinary Approach, begins with the loveliest four-paragraph description of the general circulation of the Earth's atmosphere I have ever encountered. His writing also shines in his descriptions of the climate record of the past few thousand years, and in his introduction to the measurement of climate change. Unfortunately, the book is marred by inconsistencies in its treatment of climate dynamics, as well as by a number of idiosyncratic choices of emphasis that detract from the book's quality as a general introduction to the science of climate change.
Bright THz Instrument and Nonlinear THz Science
2017-10-30
darkness” Princeton International School of Math and Sciences, Princeton, NY, May 12, 2017. 7. “THz: Imaging Beyond Light” Open Readings 2017, 60th...June 19, 2017. 6. “Let light shine out of darkness” Princeton International School of Math and Sciences, Princeton, NY, May...a graduate of Ph.D. in science, math , engineering, or technology fields 0 Number who achieved a 3.5 GPA to 4.0 (4.0 max
Using the orbiting companion to trace WR wind structures in the 29d WC8d + O8-9IV binary CV Ser
NASA Astrophysics Data System (ADS)
David-Uraz, Alexandre; Moffat, Anthony F. J.
2011-07-01
We have used continuous, high-precision, broadband visible photometry from the MOST satellite to trace wind structures in the WR component of CV Ser over more than a full orbit. Most of the small-scale light-curve variations are likely due to extinction by clumps along the line of sight to the O companion as it orbits and shines through varying columns of the WR wind. Parallel optical spectroscopy from the Mont Megantic Observatory is used to refine the orbital and wind-collision parameters, as well as to reveal line emission from clumps.
Kantsyrev, V L; Chuvatin, A S; Rudakov, L I; Velikovich, A L; Shrestha, I K; Esaulov, A A; Safronova, A S; Shlyaptseva, V V; Osborne, G C; Astanovitsky, A L; Weller, M E; Stafford, A; Schultz, K A; Cooper, M C; Cuneo, M E; Jones, B; Vesey, R A
2014-12-01
A compact Z-pinch x-ray hohlraum design with parallel-driven x-ray sources is experimentally demonstrated in a configuration with a central target and tailored shine shields at a 1.7-MA Zebra generator. Driving in parallel two magnetically decoupled compact double-planar-wire Z pinches has demonstrated the generation of synchronized x-ray bursts that correlated well in time with x-ray emission from a central reemission target. Good agreement between simulated and measured hohlraum radiation temperature of the central target is shown. The advantages of compact hohlraum design applications for multi-MA facilities are discussed.
Henricks examines the computer systems under the Spacelab floor
1996-07-09
STS078-432-009 (20 June-7 July 1996) --- Among the inflight maintenance (IFM) chores that were handled by the crew members during their almost 17 days in space aboard the space shuttle Columbia was one that involved going into the bay beneath the floor of the Life and Microgravity Spacelab (LMS-1) Science Module. Astronaut Terence T. (Tom) Henricks, mission commander, shines a tiny flashlight onto some cables related to LMS-1 supported computer systems. As in the case of the other IFM chores, Henricks' efforts were successful. He was joined by four other NASA astronauts and two international payload specialists for the space shuttle duration record-setting mission.
Straus, Sharon E; Sales, Anne; Wensing, Michel; Michie, Susan; Kent, Bridie; Foy, Robbie
2015-09-28
Alongside the growth in interest in implementation science, there has been a marked increase in training programs, educational courses, degrees, and other offerings in implementation research and practice to meet the demand for this expertise. We believe that the science of capacity building has matured but that we can advance it further by shining light on excellent work in this area and by highlighting gaps for future research. At Implementation Science, we regularly receive manuscripts that describe or evaluate training materials, competencies, and competency development in implementation curricula. We are announcing a renewed interest in manuscripts in this area, with specifications described below.
Determination of chlorine in silicate rocks
Peck, L.C.
1959-01-01
In a rapid accurate method for the determination of chlorine in silicate rocks, the rock powder is sintered with a sodium carbonate flux containing zinc oxide and magnesium carbonate. The sinter cake is leached with water, the resulting solution is filtered, and the filtrate is acidified with nitric acid. Chlorine is determined by titrating this solution with mercuric nitrate solution using sodium nitroprusside as the indicator. The titration is made in the dark with a beam of light shining through the solution. The end point of the titration is found by visually comparing the intensity of this beam of light with that of a similar beam of light in a reference solution.
Experiment to measure vacuum birefringence: Conceptual design
NASA Astrophysics Data System (ADS)
Mueller, Guido; Tanner, David; Doebrich, Babette; Poeld, Jan; Lindner, Axel; Willke, Benno
2016-03-01
Vacuum birefringence is another lingering challenge which will soon become accessible to experimental verification. The effect was first calculated by Euler and Heisenberg in 1936 and is these days described as a one-loop correction to the differential index of refraction between light which is polarized parallel and perpendicular to an external magnetic field. Our plan is to realize (and slightly modify) an idea which was originally published by Hall, Ye, and Ma using advanced LIGO and LISA technology and the infrastructure of the ALPS light-shining-through-walls experiment following the ALPS IIc science run. This work is supported by the Deutsche Forschungsgemeinschaft and the Heising-Simons Foundation.
NASA Astrophysics Data System (ADS)
Fegley, B., Jr.
Venus is Earth's nearest planetary neighbor and has fascinated mankind since the dawn of history. Venus' clouds reflect most of the sunlight shining on the planet and make it the brightest object in the sky after the Sun and Moon. Venus is visible with the naked eye as an evening star until a few hours after sunset or as a morning star shortly before sunrise. Many ancient civilizations observed and worshipped Venus, which had a different name in each society, for example, Ishtar to the Babylonians, Aphrodite to the Greeks, Tai'pei to the Chinese, and Venus to the Romans. Venus has continued to play an important role in myth, literature, and science throughout history.
Laser-speckle-visibility acoustic spectroscopy in soft turbid media.
Wintzenrieth, Frédéric; Cohen-Addad, Sylvie; Le Merrer, Marie; Höhler, Reinhard
2014-01-01
We image the evolution in space and time of an acoustic wave propagating along the surface of turbid soft matter by shining coherent light on the sample. The wave locally modulates the speckle interference pattern of the backscattered light, which is recorded using a camera. We show both experimentally and theoretically how the temporal and spatial correlations in this pattern can be analyzed to obtain the acoustic wavelength and attenuation length. The technique is validated using shear waves propagating in aqueous foam. It may be applied to other kinds of acoustic waves in different forms of turbid soft matter such as biological tissues, pastes, or concentrated emulsions.
Laser-speckle-visibility acoustic spectroscopy in soft turbid media
NASA Astrophysics Data System (ADS)
Wintzenrieth, Frédéric; Cohen-Addad, Sylvie; Le Merrer, Marie; Höhler, Reinhard
2014-01-01
We image the evolution in space and time of an acoustic wave propagating along the surface of turbid soft matter by shining coherent light on the sample. The wave locally modulates the speckle interference pattern of the backscattered light, which is recorded using a camera. We show both experimentally and theoretically how the temporal and spatial correlations in this pattern can be analyzed to obtain the acoustic wavelength and attenuation length. The technique is validated using shear waves propagating in aqueous foam. It may be applied to other kinds of acoustic waves in different forms of turbid soft matter such as biological tissues, pastes, or concentrated emulsions.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zanotto, Simone; Melloni, Andrea
By hybrid integration of plasmonic and dielectric waveguide concepts, it is shown that nearly perfect coherent absorption can be achieved in a co-propagating coupler geometry. First, the operating principle of the proposed device is detailed in the context of a more general 2 × 2 lossy coupler formalism. Then, it is shown how to tune the device in a wide region of possible working points, its broadband operation, and the tolerance to fabrication uncertainties. Finally, a complete picture of the electromagnetic modes inside the hybrid structure is analyzed, shining light onto the potentials which the proposed device holds in viewmore » of classical and quantum signal processing, nonlinear optics, polarization control, and sensing.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Simpkins, A.A.
1996-09-01
AXAOTHER XL is an Excel Spreadsheet used to determine dose to the maximally exposed offsite individual during high-velocity straight winds or tornado conditions. Both individual and population doses may be considered. Potential exposure pathways are inhalation and plume shine. For high-velocity straight winds the spreadsheet has the capability to determine the downwind relative air concentration, however for the tornado conditions, the user must enter the relative air concentration. Theoretical models are discussed and hand calculations are performed to ensure proper application of methodologies. A section has also been included that contains user instructions for the spreadsheet.
Towards a sociology of healthcare safety and quality.
Allen, Davina; Braithwaite, Jeffrey; Sandall, Jane; Waring, Justin
2016-02-01
The contributions to this collection address technologies, practices, experiences and the organisation of quality and safety across a wide range of healthcare contexts. Spanning three continents, from hospital to community, maternity to mental health, they shine a light into the boardrooms, back offices and front-lines of healthcare, offering sociological insights from the perspectives of managers, clinicians and patients. We review these articles and consider how they contribute to some of the dilemmas that confront mainstream approaches to quality and safety and then look ahead to outline future lines of sociological inquiry to progress the theory and practice of quality and safety. © 2015 Foundation for the Sociology of Health & Illness.
STS-108 Endeavour Launch from Pad 39-B
NASA Technical Reports Server (NTRS)
2001-01-01
STS-108 Endeavour Launch from Pad 39-B KSC-01PD-1786 KENNEDY SPACE CENTER, Fla. -- Like a lighted taper, Space Shuttle Endeavour shines atop its twisted contrail as it soars into space on mission STS-108. Liftoff occurred at 5:19:28 p.m. EST (10:19.28 GMT). Endeavour will dock with the International Space Station on Dec. 7. STS-108 is the final Shuttle mission of 2001and the 107th Shuttle flight overall. It is the 12th flight to the Space Station. Landing of the orbiter at KSC's Shuttle Landing Facility is targeted for 1:05 p.m. EST (6:05 p.m. GMT) Dec. 16.
Kerfoot, Karlene
2005-01-01
Leaders have the ability to create confidence or fear in the organization. Kanter (2004) writes that confidence is the "...sweet spot between arrogance and despair" (p. 8). Overconfidence causes people to overshoot, and to assume they are invulnerable. Under-confidence is just as harmful because it leads to under-investing in people, under-innovating, and eventually leads to the disenfranchisement of staff and poor morale. If we take Kanter's advice, we will build an infrastructure that creates confidence in everyone and the organization. But we will not stop there. We will focus "flashlights" on people and activities that are inspiring to others.
Kerfoot, Karlene
2004-01-01
Leaders have the ability to create confidence or fear in the organization. Kanter (2004) writes that confidence is the "...sweet spot between arrogance and despair" (p. 8). Overconfidence causes people to overshoot, and to assume they are invulnerable. Under-confidence is just as harmful because it leads to under-investing in people, under-innovating, and eventually leads to the disenfranchisement of staff and poor morale. If we take Kanter's advice, we will build an infrastructure that creates confidence in everyone and the organization. But we will not stop there. We will focus "flashlights" on people and activities that are inspiring to others.
Kerfoot, Karlene
2005-04-01
Leaders have the ability to create confidence or fear in the organization. Kanter (2004) writes that confidence is the "...sweet spot between arrogance and despair" (p. 8). Overconfidence causes people to overshoot, and to assume they are invulnerable. Underconfidence is just as harmful because it leads to underinvesting in people, under-innovating, and eventually leads to the disenfranchisement of staff and poor morale. If we take Kanter's advice, we will build an infrastructure that creates confidence in everyone and the organization. But we will not stop there. We will focus "flashlights" on people and activities that are inspiring to others.
Edwards nXDS15iC Vacuum Scroll Pump Pressure Testing
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sessions, H.; Morgan, G. A.
2013-07-17
The SRNL High Pressure Laboratory performed testing on an Edwards Model nXDS15iC Vacuum Scroll Pump on July 10th and 11th of 2013 at 723-A. This testing was done in an attempt to obtain initial compression ratio information for the nXDS15iC pump, with compression ratio defined as discharge pressure of the pump divided by suction pressure. Pressure burst testing was also done on the pump to determine its design pressure for pressure safety reasons. The Edwards nXDS15iC pump is being evaluated by SRNL for use part of the SHINE project being executed by SRNL.
NASA Astrophysics Data System (ADS)
Rolf, Christian; Vogel, Bärbel; Hoor, Peter; Günther, Gebhard; Krämer, Martina; Müller, Rolf; Müller, Stephan; Riese, Martin
2017-04-01
Water vapor plays a key role in determining the radiative balance in the upper troposphere and lower stratosphere (UTLS) and thus the climate of the Earth (Forster and Shine, 2002; Riese et al., 2012). Therefore a detailed knowledge about transport pathways and exchange processes between troposphere and stratosphere is required to understand the variability of water vapor in this region. The Asian monsoon anticyclone caused by deep convection over and India and east Asia is able to transport air masses from the troposphere into the nothern extra-tropical stratosphere (Müller et al. 2016, Vogel et al. 2016). These air masses contain pollution but also higher amounts of water vapor. An increase in water vapor of about 0.5 ppmv in the extra-tropical stratosphere above a potential temperature of 380 K was detected between August and September 2012 by in-situ instrumentation above the European northern hemisphere during the HALO aircraft mission TACTS. Here, we investigated the origin of this water vapor increase with the help of the 3D Lagrangian chemistry transport model CLaMS (McKenna et al., 2002). We can assign an origin of the moist air masses in the Asian region (North and South India and East China) with the help of model origin tracers. Additionally, back trajectories of these air masses with enriched water vapor are used to differentiate between transport from the Asia monsoon anticyclone and the upwelling of moister air in the tropics particularly from the Pacific and Southeast Asia.
García-Gómez, Elizabeth; Jaso-Vera, Marcos E; Juárez-Verdayes, Marco A; Alcántar-Curiel, María D; Zenteno, Juan C; Betanzos-Cabrera, Gabriel; Peralta, Humberto; Rodríguez-Martínez, Sandra; Cancino-Díaz, Mario E; Jan-Roblero, Janet; Cancino-Diaz, Juan C
2017-02-01
In the Staphylococcus aureus ATCC25923 strain, the flqB mutation in the 5'untranslated region (5'UTR) of the norA gene causes increased norA mRNA expression and high efflux activity (HEA). The involvement of the norA gene 5'UTR in HEA has not been explored in S. epidermidis; therefore, we examined the function of this region in S. epidermidis clinical isolates. The selection of isolates with HEA was performed based on ethidium bromide (EtBr) MIC values and efflux efficiency (EF) using the semi-automated fluorometric method. The function of the 5'UTR was studied by quantifying the levels of norA expression (RT-qPCR) and by identifying 5'UTR mutations by sequence analysis. Only 10 isolates from a total of 165 (6.1%) had HEA (EtBr MIC = 300 μg/ml and EF ranged from 48.4 to 97.2%). Eight of 10 isolates with HEA had the 5'UTR 95 Δ G mutation. Isolates carrying the 95 Δ G mutation had higher levels of norA expression compared with those that did not. To corroborate that the 95 Δ G mutation is involved in HEA, a strain adapted to EtBr was obtained in vitro. This strain also presented the 95 Δ G mutation and had a high level of norA expression and EF, indicating that the 95 Δ G mutation is important for the HEA phenotype. The 95 Δ G mutation produces a different structure in the Shine-Dalgarno region, which may promote better translation of norA mRNA. To our knowledge, this is the first report to demonstrate the participation of the 5'UTR 95 Δ G mutation of the norA gene in the HEA phenotype of S. epidermidis isolates. Here, we propose that the efflux of EtBr is caused by an increment in the transcription and/or translation of the norA gene. Copyright © 2016 Elsevier Ltd. All rights reserved.
Knowledge information management toolkit and method
Hempstead, Antoinette R.; Brown, Kenneth L.
2006-08-15
A system is provided for managing user entry and/or modification of knowledge information into a knowledge base file having an integrator support component and a data source access support component. The system includes processing circuitry, memory, a user interface, and a knowledge base toolkit. The memory communicates with the processing circuitry and is configured to store at least one knowledge base. The user interface communicates with the processing circuitry and is configured for user entry and/or modification of knowledge pieces within a knowledge base. The knowledge base toolkit is configured for converting knowledge in at least one knowledge base from a first knowledge base form into a second knowledge base form. A method is also provided.
Golaszewski, T
2001-01-01
To examine the literature from the past 20 years and identify those studies that support the economic merit of health promotion. A panel of experts was used to identify the top studies supporting the purpose of this article. Studies were chosen based on the following criteria: the study (1) examined the relationship between health risks and financial outcomes, or health promotion programs and financial outcomes; (2) provided strong and compelling financial data supporting the worth of health promotion; (3) had a high-quality methodology; (4) answered an important question or replicated important findings with superior methodology; and (5) represented U.S.-based initiatives published since 1980. After initially nominating a group of studies for consideration, panelists rated each on a scale from 1 to 3 representing their opinion of importance. Studies rating the highest were included for this discussion. Studies were analyzed by population characteristics, design, statistical tests, limitations, and results. This information was summarized for each identified article. A relationship between modifiable health risk factors and health care costs is supported by research. Health promotion interventions appear to provide positive financial returns, most notably for health care costs and absenteeism reduction. Private sector initiatives seem to be driving economic-based research. Overall, health promotion shows promising results for providing financial advantages for its sponsors; however, if this discipline is to show its true worth, considerable funding is needed from government or philanthropic sources to cover the substantial costs of quality research.
Eye-safe digital 3-D sensing for space applications
NASA Astrophysics Data System (ADS)
Beraldin, J.-Angelo; Blais, Francois; Rioux, Marc; Cournoyer, Luc; Laurin, Denis G.; MacLean, Steve G.
2000-01-01
This paper focuses on the characteristics and performance of an eye-safe laser range scanner (LARS) with short- and medium-range 3D sensing capabilities for space applications. This versatile LARS is a precision measurement tool that will complement the current Canadian Space Vision System. The major advantages of the LARS over conventional video- based imaging are its ability to operate with sunlight shining directly into the scanner and its immunity to spurious reflections and shadows, which occur frequently in space. Because the LARS is equipped with two high-speed galvanometers to steer the laser beam, any spatial location within the field of view of the camera can be addressed. This versatility enables the LARS to operate in two basis scan pattern modes: (1) variable-scan-resolution mode and (2) raster-scan mode. In the variable-resolution mode, the LARS can search and track targets and geometrical features on objects located within a field of view of 30 by 30 deg and with corresponding range from about 0.5 to 2000 m. The tracking mode can reach a refresh rate of up to 130 Hz. The raster mode is used primarily for the measurement of registered range and intensity information on large stationary objects. It allows, among other things, target- based measurements, feature-based measurements, and surface- reflectance monitoring. The digitizing and modeling of human subjects, cargo payloads, and environments are also possible with the LARS. Examples illustrating its capabilities are presented.
Effects of the turbulent ISM on radio observations of quasars
NASA Astrophysics Data System (ADS)
Gabányi, Krisztina; Britzen, S.; Krichbaum, T. P.; Bach, U.; Fuhrmann, L.; Kraus, A.; Witzel, A.; Zensus, J. A.
In radio bands, the study of compact radio sources can be affected by propagation effects introduced by the interstellar medium, usually attributed to the presence of turbulent intervening plasma along the line of sight. Here, two of such effects are presented. The line of sight of B 2005+403 passes through the heavily scattered region of Cygnus causing substantial angular broadening of the source images obtained at frequencies between 0.6 GHz and 8 GHz. At higher frequencies, however, the intrinsic source structure shines through. Therefore, multi-frequency VLBI observations allow to study the characteristics of the intervening material, the source morphology and the interplay between them in forming the observed image.
Derivatives of Black Knight Technology
NASA Astrophysics Data System (ADS)
Hill, N.; Wright, D.
This paper traces the line of descent from Black Knight to Black Arrow, and at the same time looks at various proposed projects, both civil and military, which were to be Black Knight derivatives, but which for one reason or another never saw the light of day. Research in this area is rather akin to anthropological work, tracing fossils from Homo erectus (Black Knight) to Homo sapiens (Black Arrow), knowing that a lot of the fossils found will not be on the direct line of descent, but represent branches that became extinct. This article attempts to cover designs, which, although they never made it to hardware, are none the less interesting technically, or shine light on the evolution of design philosophy.