Employment Trends; Eating and Beverage Establishments 1958 to 1968, Louisiana.

ERIC Educational Resources Information Center

Louisiana State Dept. of Employment Security, Baton Rouge

Employment in eating and beverage establishments has grown tremendously in Louisiana. In 1940, United States Census figures showed that 18,400 were employed in the industry, and by 1969, the number had increased to 31,000. The situation in Louisiana may not be typical of other states because of a sharp increase in catering services to offshore oil…

Density functional study of structural and electronic properties of Al{sub n}@C{sub 60}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dhiman, Shobhna, E-mail: s-dhiman@hotmail.com; Kumar, Ranjan; Dharamvir, Keya

2014-04-24

Fullerene derivatives have been shown to make contributions in many types of applications. Ab initio investigation of structural and electronic properties of aluminum doped endohedral fullerene has been performed using numerical atomic orbital density functional theory. We have obtained ground state structures for Al{sub n}@C{sub 60} (n=1–10). Which shows that C{sub 60} molecule can accommodate maximum of nine aluminum atoms, for n > 9 the cage eventually break. Encapsulated large number of aluminum atoms leads to deformation of cage with diameter varies from 7.16Å to 7.95Å. Binding energy/Al atom is found to increase till n = 4 and after thatmore » it decreases with the number of Al atoms with a sudden increase for n=10 due to breakage of C{sub 60} cage and electronic affinity first increases till n=4 then it decreases up to n=9 with a sharp increase for n=10. Ionization potential also first increases and then decreases. Homo-Lumo gap decreases till n=3 with a sharp increase for n=4, after that it shows an oscillatory nature. The results obtained are consistent with available theoretical and experimental results. The ab-initio calculations were performed using SIESTA code with generalized gradient approximation (GGA)« less

Hypersonic boundary-layer transition measurements at Mach 10 on a large seven-degree cone at angle of attack

NASA Astrophysics Data System (ADS)

Moraru, Ciprian G.

The ability to predict the onset of boundary-layer transition is critical for hypersonic flight vehicles. The development of prediction methods depends on a thorough comprehension of the mechanisms that cause transition. In order to improve the understanding of hypersonic boundary-layer transition, tests were conducted on a large 7° half-angle cone at Mach 10 in the Arnold Engineering Development Complex Wind Tunnel 9. Twenty-four runs were performed at varying unit Reynolds numbers and angles of attack for sharp and blunt nosetip configurations. Heat-transfer measurements were used to determine the start of transition on the cone. Increasing the unit Reynolds number caused a forward movement of transition on the sharp cone at zero angle of attack. Increasing nosetip radius delayed transition up to a radius of 12.7 mm. Larger nose radii caused the start of transition to move forward. At angles of attack up to 10°, transition was leeside forward for nose radii up to 12.7 mm and windside forward for nose radii of 25.4 mm and 50.8 mm. Second-mode instability waves were measured on the sharp cone and cones with small nose radii. At zero angle of attack, waves at a particular streamwise location on the sharp cone were in earlier stages of development as the unit Reynolds number was decreased. The same trend was observed as the nosetip radius was increased. No second-mode waves were apparent for the cones with large nosetip radii. As the angle of attack was increased, waves at a particular streamwise location on the sharp cone moved to earlier stages of growth on the windward ray and later stages of growth on the leeward ray. RMS amplitudes of second-mode waves were computed. Comparison between maximum second-mode amplitudes and edge Mach numbers showed good correlation for various nosetip radii and unit Reynolds numbers. Using the e N method, initial amplitudes were estimated and compared to freestream noise in the second-mode frequency band. Correlations indicate that freestream noise likely has a significant influence on initial second-mode amplitudes.

The Relevance of Culturally Based Curriculum and Instruction: The Case of Nancy Sharp

ERIC Educational Resources Information Center

Lipka, Jerry; Sharp, Nancy; Brenner, Betsy; Yanez, Evelyn; Sharp, Ferdinand

2005-01-01

Ms. Sharp's case is particularly instructive as it shows how this experienced Yup'ik teacher steeped in the traditions of her culture effectively implemented a culturally based math module. Ms. Sharp's pedagogical creatively allowed her to authentically bring together a core academic content area, math, with Yup'ik traditions, knowledge, and ways…

Sharp Injuries Among Medical Students.

PubMed

Ghasemzadeh, Iman; Kazerooni, Mitra; Davoodian, Parivash; Hamedi, Yaghoob; Sadeghi, Payam

2015-03-30

Sharp injuries threaten the health of healthcare employees. They cause the transmission of many diseases such as hepatitis B and C, AIDS, etc., which can increase the associated costs associated with them. The aim of this study was to investigate the frequency of sharp injuries among the students of Hormozgan University of Medical Sciences. This cross-sectional study was conducted during 2012-2013 in Hormozgan University of Medical Sciences, IR Iran. The target population consisted of the medical, nursing, midwifery, operating room technician, and medical laboratory students in the 2012-2013 academic year. Census sampling was conducted, and accordingly, 500 students participated in the study Data was collected using modified questionnaire of the University of San Diego's injury report form. The collected data were entered into SPSS V.19 and analyzed using descriptive statistical tests. Finally 377 students (75.4%) returned the questionnaire. Among the studied students, 184 students (39.3%) had had sharp injuries. The frequency of damaging Vein puncture was the most common mechanism of injury The prevalence of sharp injuries is high among students which can increase the risk of disease and its subsequent risks, and thus, increase the cost and stress among students. It seems that holding workshops and increasing students' awareness and skills to face these risks can be effective in mitigating them.

Long working hours increase the risk of sharp and needlestick injury in nurses: the need for new policy implication.

PubMed

Ilhan, Mustafa N; Durukan, Elif; Aras, Evin; Türkçüoğlu, Sertaç; Aygün, Remzi

2006-12-01

This paper reports a study to determine the sharp and needlestick injury incidence in nurses working at a university hospital and the contributing factors. Although it is generally felt that working in the healthcare sector is clean and without risk, healthcare staff and especially physicians and nurses who generally work very long hours are actually exposed to various occupational risks. Sharps and needlestick injuries are important problems for healthcare workers as they increase the risk of spread of infection. A self-administered questionnaire was completed in October 2005 by 449 of the 516 nurses working at a Turkish hospital (response rate 87.0%). The percentage of nurses experiencing a sharp or needlestick injury during their professional life was 79.7%. The incidence of exposure to sharp or needlestick injury in the last year was 68.4%. The factors increasing the rate of sharp and needlestick injury were: age 24 years and less,

Enhancements to the SHARP Build System and NEK5000 Coupling

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCaskey, Alex; Bennett, Andrew R.; Billings, Jay Jay

The SHARP project for the Department of Energy's Nuclear Energy Advanced Modeling and Simulation (NEAMS) program provides a multiphysics framework for coupled simulations of advanced nuclear reactor designs. It provides an overall coupling environment that utilizes custom interfaces to couple existing physics codes through a common spatial decomposition and unique solution transfer component. As of this writing, SHARP couples neutronics, thermal hydraulics, and structural mechanics using PROTEUS, Nek5000, and Diablo respectively. This report details two primary SHARP improvements regarding the Nek5000 and Diablo individual physics codes: (1) an improved Nek5000 coupling interface that lets SHARP achieve a vast increase inmore » overall solution accuracy by manipulating the structure of the internal Nek5000 spatial mesh, and (2) the capability to seamlessly couple structural mechanics calculations into the framework through improvements to the SHARP build system. The Nek5000 coupling interface now uses a barycentric Lagrange interpolation method that takes the vertex-based power and density computed from the PROTEUS neutronics solver and maps it to the user-specified, general-order Nek5000 spectral element mesh. Before this work, SHARP handled this vertex-based solution transfer in an averaging-based manner. SHARP users can now achieve higher levels of accuracy by specifying any arbitrary Nek5000 spectral mesh order. This improvement takes the average percentage error between the PROTEUS power solution and the Nek5000 interpolated result down drastically from over 23 % to just above 2 %, and maintains the correct power profile. We have integrated Diablo into the SHARP build system to facilitate the future coupling of structural mechanics calculations into SHARP. Previously, simulations involving Diablo were done in an iterative manner, requiring a large amount manual work, and left only as a task for advanced users. This report will detail a new Diablo build system that was implemented using GNU Autotools, mirroring much of the current SHARP build system, and easing the use of structural mechanics calculations for end-users of the SHARP multiphysics framework. It lets users easily build and use Diablo as a stand-alone simulation, as well as fully couple with the other SHARP physics modules. The top-level SHARP build system was modified to allow Diablo to hook in directly. New dependency handlers were implemented to let SHARP users easily build the framework with these new simulation capabilities. The remainder of this report will describe this work in full, with a detailed discussion of the overall design philosophy of SHARP, the new solution interpolation method introduced, and the Diablo integration work. We will conclude with a discussion of possible future SHARP improvements that will serve to increase solution accuracy and framework capability.« less

Moving graphene devices from lab to market: advanced graphene-coated nanoprobes

NASA Astrophysics Data System (ADS)

Hui, Fei; Vajha, Pujashree; Shi, Yuanyuan; Ji, Yanfeng; Duan, Huiling; Padovani, Andrea; Larcher, Luca; Li, Xiao Rong; Xu, Jing Juan; Lanza, Mario

2016-04-01

After more than a decade working with graphene there is still a preoccupying lack of commercial devices based on this wonder material. Here we report the use of high-quality solution-processed graphene sheets to fabricate ultra-sharp probes with superior performance. Nanoprobes are versatile tools used in many fields of science, but they can wear fast after some experiments, reducing the quality and increasing the cost of the research. As the market of nanoprobes is huge, providing a solution for this problem should be a priority for the nanotechnology industry. Our graphene-coated nanoprobes not only show enhanced lifetime, but also additional unique properties of graphene, such as hydrophobicity. Moreover, we have functionalized the surface of graphene to provide piezoelectric capability, and have fabricated a nano relay. The simplicity and low cost of this method, which can be used to coat any kind of sharp tip, make it suitable for the industry, allowing production on demand.After more than a decade working with graphene there is still a preoccupying lack of commercial devices based on this wonder material. Here we report the use of high-quality solution-processed graphene sheets to fabricate ultra-sharp probes with superior performance. Nanoprobes are versatile tools used in many fields of science, but they can wear fast after some experiments, reducing the quality and increasing the cost of the research. As the market of nanoprobes is huge, providing a solution for this problem should be a priority for the nanotechnology industry. Our graphene-coated nanoprobes not only show enhanced lifetime, but also additional unique properties of graphene, such as hydrophobicity. Moreover, we have functionalized the surface of graphene to provide piezoelectric capability, and have fabricated a nano relay. The simplicity and low cost of this method, which can be used to coat any kind of sharp tip, make it suitable for the industry, allowing production on demand. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr06235g

INFORMATIONAL STRESS AS A DEPRESSION INDUCING FACTOR (EXPERIMENTAL STUDY).

PubMed

Matitaishvili, T; Domianidze, T; Burdjanadze, G; Nadareishvili, D; Khananashvili, M

2017-01-01

Chronic psychogenic stress represents the major initiating agent of psychoneural diseases including depression. We used informational stress model for the purpose of modelling chronic psychogenic stress and depression. The aim of the research was to study behavior of dominant and submissive rats at different stages of informational stress and during depression state. In order to study anxiety and depressive behavior of rats we used "forced swim", "elevated cross maze" and "open-field" tests. The obtained results showed that chronic stressing procedure performed on rats by using the mentioned "informational" stress model led to the development of depression both in dominant and submissive rats. Stressing procedure caused sharp increase of serotonin concentration in hypothalamus of dominant and submissive rats. Under behavioral depression background, sharp increase of serotonin concentration in hypothalamus has been revealed which is caused by the peculiarities of stress model (by uncontrollable stressor. Specifically, by inevitable electric painful irritation).

Wetting-Dewetting and Dispersion-Aggregation Transitions Are Distinct for Polymer Grafted Nanoparticles in Chemically Dissimilar Polymer Matrix.

PubMed

Martin, Tyler B; Mongcopa, Katrina Irene S; Ashkar, Rana; Butler, Paul; Krishnamoorti, Ramanan; Jayaraman, Arthi

2015-08-26

Simulations and experiments are conducted on mixtures containing polymer grafted nanoparticles in a chemically distinct polymer matrix, where the graft and matrix polymers exhibit attractive enthalpic interactions at low temperatures that become progressively repulsive as temperature is increased. Both coarse-grained molecular dynamics simulations, and X-ray scattering and neutron scattering experiments with deuterated polystyrene (dPS) grafted silica and poly(vinyl methyl ether) PVME matrix show that the sharp phase transition from (mixed) dispersed to (demixed) aggregated morphologies due to the increasingly repulsive effective interactions between the blend components is distinct from the continuous wetting-dewetting transition. Strikingly, this is unlike the extensively studied chemically identical graft-matrix composites, where the two transitions have been considered to be synonymous, and is also unlike the free (ungrafted) blends of the same graft and matrix homopolymers, where the wetting-dewetting is a sharp transition coinciding with the macrophase separation.

Electronic Transport and Possible Superconductivity at Van Hove Singularities in Carbon Nanotubes.

PubMed

Yang, Y; Fedorov, G; Shafranjuk, S E; Klapwijk, T M; Cooper, B K; Lewis, R M; Lobb, C J; Barbara, P

2015-12-09

Van Hove singularities (VHSs) are a hallmark of reduced dimensionality, leading to a divergent density of states in one and two dimensions and predictions of new electronic properties when the Fermi energy is close to these divergences. In carbon nanotubes, VHSs mark the onset of new subbands. They are elusive in standard electronic transport characterization measurements because they do not typically appear as notable features and therefore their effect on the nanotube conductance is largely unexplored. Here we report conductance measurements of carbon nanotubes where VHSs are clearly revealed by interference patterns of the electronic wave functions, showing both a sharp increase of quantum capacitance, and a sharp reduction of energy level spacing, consistent with an upsurge of density of states. At VHSs, we also measure an anomalous increase of conductance below a temperature of about 30 K. We argue that this transport feature is consistent with the formation of Cooper pairs in the nanotube.

Teacher Leaders in Denver Public Schools

ERIC Educational Resources Information Center

Nazareno, Lori

2015-01-01

Teachers are increasingly dissatisfied. In one recent survey, 47 percent of teachers said they were not enthusiastic about their jobs, and another showed a sharp drop in teacher satisfaction since 2008, from 62 to 39 percent. This dissatisfaction does not stem from what one might think--stresses related to dealing with students and families.…

Synthesis and structural studies of praseodymium doped silver borate glasses

NASA Astrophysics Data System (ADS)

Jagadeesha Gowda, G. V.; Eraiah, B.

2013-02-01

Praseodymium doped silver borate glasses with nominal composition xPr6O11-(25-x)Ag2O-75B2O3 (x=0, 1, 2, 3, 4, 5) were prepared by melt quench technique. XRD pattern shows that there is no sharp peak it confirms the amorphous nature of the present glasses. The glass transition temperature (Tg) of this glass system have been studied using the Matac MBS-8000 Digital Signal Processing and Conventional Thermal Analysis (DTA) method. The Tg of these glasses increases with increase in concentration of Pr6O11 except at 0.2 mol%, Tg value is lower. 11B MAS-NMR shows the presence of sharp peak around 0.306 ppm. Chemical shift of these glasses decreases with mol% of rare earth oxide. FTIR spectra recorded in the region of 400 to 4000 cm-1. This studies revealed that the progressive addition Ag2O and Pr6O11 leads to modification of B2O3 into BO4 groups. Raman measurements of these glasses support the proposed interpretations of the experimental results.

Sharp low-energy feature in single-particle spectra due to forward scattering in d-wave cuprate superconductors.

PubMed

Hong, Seung Hwan; Bok, Jin Mo; Zhang, Wentao; He, Junfeng; Zhou, X J; Varma, C M; Choi, Han-Yong

2014-08-01

There is an enormous interest in the renormalization of the quasiparticle (qp) dispersion relation of cuprate superconductors both below and above the critical temperature T_{c} because it enables the determination of the fluctuation spectrum to which the qp's are coupled. A remarkable discovery by angle-resolved photoemission spectroscopy (ARPES) is a sharp low-energy feature (LEF) in qp spectra well below the superconducting energy gap but with its energy increasing in proportion to T_{c} and its intensity increasing sharply below T_{c}. This unexpected feature needs to be reconciled with d-wave superconductivity. Here, we present a quantitative analysis of ARPES data from Bi_{2}Sr_{2}CaCu_{2}O_{8+δ} (Bi2212) using Eliashberg equations to show that the qp scattering rate due to the forward scattering impurities far from the Cu-O planes is modified by the energy gap below T_{c} and shows up as the LEF. This is also a necessary step to analyze ARPES data to reveal the spectrum of fluctuations promoting superconductivity.

Highly tunable magnetism in silicene doped with Cr and Fe atoms under isotropic and uniaxial tensile strain

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zheng, Rui; Ni, Jun, E-mail: junni@mail.tsinghua.edu.cn; Collaborative Innovative Center of Quantum Matter, Beijing 100084

2015-12-28

We have investigated the magnetic properties of silicene doped with Cr and Fe atoms under isotropic and uniaxial tensile strain by the first-principles calculations. We find that Cr and Fe doped silicenes show strain-tunable magnetism. (1) The magnetism of Cr and Fe doped silicenes exhibits sharp transitions from low spin states to high spin states by a small isotropic tensile strain. Specially for Fe doped silicene, a nearly nonmagnetic state changes to a high magnetic state by a small isotropic tensile strain. (2) The magnetic moments of Fe doped silicene also show a sharp jump to ∼2 μ{sub B} at amore » small threshold of the uniaxial strain, and the magnetic moments of Cr doped silicene increase gradually to ∼4 μ{sub B} with the increase of uniaxial strain. (3) The electronic and magnetic properties of Cr and Fe doped silicenes are sensitive to the magnitude and direction of the external strain. The highly tunable magnetism may be applied in the spintronic devices.« less

Cell dialysis by sharp electrodes can cause nonphysiological changes in neuron properties

PubMed Central

Hooper, Scott L.; Guschlbauer, Christoph; Schmidt, Joachim; Büschges, Ansgar

2015-01-01

We recorded from lobster and leech neurons with two sharp electrodes filled with solutions often used with these preparations (lobster: 0.6 M K2SO4 or 2.5 M KAc; leech: 4 M KAc), with solutions approximately matching neuron cytoplasm ion concentrations, and with 6.5 M KAc (lobster, leech) and 0.6 M KAc (lobster). We measured membrane potential, input resistance, and transient and sustained depolarization-activated outward current amplitudes in leech and these neuron properties and hyperpolarization-activated current time constant in lobster, every 10 min for 60 min after electrode penetration. Neuron properties varied with electrode fill. For fills with molarities ≥2.5 M, neuron properties also varied strongly with time after electrode penetration. Depending on the property being examined, these variations could be large. In leech, cell size also increased with noncytoplasmic fills. The changes in neuron properties could be due to the ions being injected from the electrodes during current injection. We tested this possibility in lobster with the 2.5 M KAc electrode fill by making measurements only 10 and 60 min after penetration. Neuron properties still changed, although the changes were less extreme. Making measurements every 2 min showed that the time-dependent variations in neuron properties occurred in concert with each other. Neuron property changes with high molarity electrode-fill solutions were great enough to decrease neuron firing strongly. An experiment with 14C-glucose electrode fill confirmed earlier work showing substantial leak from sharp electrodes. Sharp electrode work should thus be performed with cytoplasm-matched electrode fills. PMID:26063785

Cell dialysis by sharp electrodes can cause nonphysiological changes in neuron properties.

PubMed

Hooper, Scott L; Thuma, Jeffrey B; Guschlbauer, Christoph; Schmidt, Joachim; Büschges, Ansgar

2015-08-01

We recorded from lobster and leech neurons with two sharp electrodes filled with solutions often used with these preparations (lobster: 0.6 M K2SO4 or 2.5 M KAc; leech: 4 M KAc), with solutions approximately matching neuron cytoplasm ion concentrations, and with 6.5 M KAc (lobster, leech) and 0.6 M KAc (lobster). We measured membrane potential, input resistance, and transient and sustained depolarization-activated outward current amplitudes in leech and these neuron properties and hyperpolarization-activated current time constant in lobster, every 10 min for 60 min after electrode penetration. Neuron properties varied with electrode fill. For fills with molarities ≥2.5 M, neuron properties also varied strongly with time after electrode penetration. Depending on the property being examined, these variations could be large. In leech, cell size also increased with noncytoplasmic fills. The changes in neuron properties could be due to the ions being injected from the electrodes during current injection. We tested this possibility in lobster with the 2.5 M KAc electrode fill by making measurements only 10 and 60 min after penetration. Neuron properties still changed, although the changes were less extreme. Making measurements every 2 min showed that the time-dependent variations in neuron properties occurred in concert with each other. Neuron property changes with high molarity electrode-fill solutions were great enough to decrease neuron firing strongly. An experiment with (14)C-glucose electrode fill confirmed earlier work showing substantial leak from sharp electrodes. Sharp electrode work should thus be performed with cytoplasm-matched electrode fills. Copyright © 2015 the American Physiological Society.

Timbral Sharpness and Modulations in Frequency and Amplitude: Implications for the Fusion of Musical Sounds.

NASA Astrophysics Data System (ADS)

Goad, Pamela Joy

The fusion of musical voices is an important aspect of musical blend, or the mixing of individual sounds. Yet, little research has been done to explicitly determine the factors involved in fusion. In this study, the similarity of timbre and modulation were examined for their contribution to the fusion of sounds. It is hypothesized that similar timbres will fuse better than dissimilar timbres, and, voices with the same kind of modulation will fuse better than voices of different modulations. A perceptually-based measure, known as sharpness was investigated as a measure of timbre. The advantages of using sharpness are that it is based on hearing sensitivities and masking phenomena of inner ear processing. Five musical instrument families were digitally recorded in performances across a typical playing range at two extreme dynamic levels. Analyses reveal that sharpness is capable of uncovering subtle changes in timbre including those found in musical dynamics, instrument design, and performer-specific variations. While these analyses alone are insufficient to address fusion, preliminary calculations of timbral combinations indicate that sharpness has the potential to predict the fusion of sounds used in musical composition. Three experiments investigated the effects of modulation on the fusion of a harmonic major sixth interval. In the first experiment using frequency modulation, stimuli varied in deviation about a mean fundamental frequency and relative modulation phase between the two tones. Results showed smaller frequency deviations promoted fusion and relative phase differences had a minimal effect. In a second experiment using amplitude modulation, stimuli varied in deviation about a mean amplitude level and relative phase of modulation. Results showed smaller amplitude deviations promoted better fusion, but unlike frequency modulation, relative phase differences were also important. In a third experiment, frequency modulation, amplitude modulation and mixed modulation were arranged in all possible voicings. Results showed frequency modulation in the lower voice and less variance in amplitude envelopes contributed to an increase in fusion. The theory that similar modulations would promote better fusion was only marginally supported. For these experiments, results revealed differences depending on modulation type and that a lesser amount of modulation fosters greater fusion.

Wargame Support to USAFRICOM

DTIC Science & Technology

2014-02-01

1) Fighting between Sudan and South Sudan peaked in 2002; violence shifted to Darfur in Western Sudan beginning in 2003. CAA-2011026 ii (2...between 1997 and April 2011. This graph shows the sharp drop in violence after 2002 and before the increased intensity of the conflict in Darfur in...violence shifts to Darfur beginning in 2003.  Communal violence begins take root in 2004 and gradually increases through 2009. 2009 marked the

Impact of Tropical Cyclones on Soil Moisture over East Asia

NASA Astrophysics Data System (ADS)

Liess, S.

2016-12-01

A simulation of a series of three strong typhoons (Frankie, Gloria, and Herb) during the 1996 typhoon season shows that the Weather Research and Forecasting (WRF) model is representing the general characteristics of each typhoon, including sharp right turns by Gloria and Herb over the Philippine Sea. These sharp right turns can be attributed to tropical easterly waves and they are responsible for landfall over Taiwan, instead of following the general direction toward the Philippines. A second simulation where the typhoon signal is removed before landfall over East Asia shows that both rainfall and soil moisture is increased by up to 30% in coastal regions after landfall, mostly to the north of the landfall region. However, despite the noisier signal in rainfall, significant increases in soil moisture related to the paths of the simulated typhoons occur as far west as western China and Myanmar. Strong winds associated with the typhoons can also increase local evaporation and thus locally reduce soil moisture, especially south of the landfall region. Detailed observations of hydrologic variables such as soil moisture are needed to evaluate these model studies not only over coastal regions but also further inland where typhoon signals are weaker but local moisture availability is still influenced by increased rainfall and stronger winds.

Behold Mount Sharp!

NASA Image and Video Library

2012-08-06

This image taken by NASA Curiosity shows what lies ahead for the rover -- its main science target, informally called Mount Sharp. The rover shadow can be seen in the foreground, and the dark bands beyond are dunes.

The Physics of Local Helicity Injection Non-Solenoidal Tokamak Startup

NASA Astrophysics Data System (ADS)

Redd, A. J.; Barr, J. L.; Bongard, M. W.; Fonck, R. J.; Hinson, E. T.; Jardin, S.

2013-10-01

Non-solenoidal startup via Local Helicity Injection (LHI) uses compact current injectors to produce toroidal plasma current Ip up to 170 kA in the PEGASUS Toroidal Experiment, driven by 4-8 kA injector current on timescales of 5-20 milliseconds. Increasing the Ip buildup duration enables experimental demonstration of plasma position control on timescales relevant for high-current startup. LHI-driven discharges exhibit bursty MHD activity, apparently line-tied kinking of LHI-driven field lines, with the bursts correlating with rapid equilibrium changes, sharp Ip rises, and sharp drops in the injector impedance. Preliminary NIMROD results suggest that helical LHI-driven current channels remain coherent, with Ip increases due to reconnection between adjacent helical turns forming axisymmetric plasmoids, and corresponding sharp drops in the bias circuit impedance. The DC injector impedance is consistent with a space charge limit at low bias current and a magnetic limit at high bias current. Internal measurements show the current density profile starts strongly hollow and rapidly fills in during Ip buildup. Simulations of LHI discharges using the Tokamak Simulation Code (TSC) will provide insight into the detailed current drive mechanism and guide experiments on PEFASUS and NSTX-U. Work supported by US DOE Grants DE-FG02-96ER54375 and DE-SC0006928.

Communication: Nanoscale structure of tetradecyltrihexylphosphonium based ionic liquids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hettige, Jeevapani J.; Araque, Juan C.; Margulis, Claudio J., E-mail: claudio-margulis@uiowa.edu

In a recent communication [J. J. Hettige et al., J. Chem. Phys. 140, 111102 (2014)], we investigated the anomalous temperature dependence of the X-ray first sharp diffraction peak (or prepeak) in the tetradecyltrihexylphosphonium bis(trifluoromethylsulfonyl)-amide ionic liquid. Contrary to what was expected and often observed, the first sharp diffraction peak in this system was shown to increase in intensity with increasing temperature. This implies higher intermediate-range periodicity at a higher temperature. Is this counter-intuitive behavior specific to the combination of cation and anion? The current work analyzes the structural behavior of the same cation coupled with six different anions ranging frommore » the small and spherically symmetric Cl{sup −} to the more structurally complex and charge-diffuse NTf{sub 2}{sup −}. In all cases, the same temperature behavior trend for the prepeak is observed independent of anionic nature. We will show that the intensity increase in the prepeak region is associated with the structural behavior of charged liquid subcomponents. Instead, upon a temperature increase, the apolar subcomponents contribute to what would be an expected decrease of prepeak intensity.« less

Confidence Hills -- The First Mount Sharp Drilling Site

NASA Image and Video Library

2014-11-04

This image shows the first holes drilled by NASA Mars rover Curiosity at Mount Sharp. The loose material near the drill holes is drill tailings and an accumulation of dust that slid down the rock during drilling.

First Sampling Hole in Mount Sharp

NASA Image and Video Library

2014-09-25

This image from the Mars Hand Lens Imager MAHLI camera on NASA Curiosity Mars rover shows the first sample-collection hole drilled in Mount Sharp, the layered mountain that is the science destination of the rover extended mission.

Surface-enhanced Raman scattering on periodic metal nanotips with tunable sharpness.

PubMed

Linn, Nicholas C; Sun, Chih-Hung; Arya, Ajay; Jiang, Peng; Jiang, Bin

2009-06-03

This paper reports on a scalable bottom-up technology for producing periodic gold nanotips with tunable sharpness as surface-enhanced Raman scattering (SERS) substrates. Inverted silicon pyramidal pits, which are templated from non-close-packed colloidal crystals prepared by a spin-coating technology, are used as structural templates to replicate arrays of polymer nanopyramids with nanoscale sharp tips. The deposition of a thin layer of gold on the polymer nanopyramids leads to the formation of SERS-active substrates with a high enhancement factor (up to 10(8)). The thickness of the deposited metal determines the sharpness of the nanotips and the resulting Raman enhancement factor. Finite-element electromagnetic modeling shows that the nanotips can significantly enhance the local electromagnetic field and the sharpness of nanotips greatly affects the SERS enhancement.

The impact of sharps injuries on student nurses: a systematic review.

PubMed

Hambridge, Kevin; Nichols, Andrew; Endacott, Ruth

2016-10-27

The purpose of this review was to discover the impact of sharps injuries in the student nurse population. Much is known and reported about sharps injuries in registered nurses, but there has been a lack of published evidence regarding sharps injuries within the student nurse population. A systematic review of nursing, health and psychology databases was conducted. The limits set were publications between 1980 and 2014 in the English language. Studies were identified then, following a rigorous critical and quality appraisal with validated tools, were selected for the systematic review. A total of 40 articles met the inclusion criteria, reporting studies conducted in 18 countries. Psychological and physical impacts of sharps injuries in student nurses were reported, such as fear, anxiety and depression, although these impacts were not quantified using a validated instrument. The impact of sharps injuries can be severe, both psychological and physical. This systematic review shows that further research is needed into this, especially in under-researched areas such as the UK, to establish the impact of sharps injuries within this population. Further research would also aid the education and prevention of this harmful problem. The review also emphasises the psychological issues relating to sharps injuries, the impact these can have on individuals and the support and counselling that student nurses require after injury. These findings highlight the potential psychological issues that can result from sharps injuries in this population.

Maintaining knife sharpness in industrial meat cutting: A matter of knife or meat cutter ability.

PubMed

Karltun, J; Vogel, K; Bergstrand, M; Eklund, J

2016-09-01

Knife sharpness is imperative in meat cutting. The aim of this study was to compare the impact of knife blade steel quality with meat cutters' individual ability to maintain the cutting edge sharp in an industrial production setting. Twelve meat cutters in two different companies using three different knives during normal production were studied in this quasi-experimental study. Methods included were measuring knife cutting force before and after knife use, time knives were used, ratings of sharpness and discomfort and interviews. Results showed that the meat cutters' skill of maintaining sharpness during work had a much larger effect on knife sharpness during work than the knife steel differences. The ability was also related to feelings of discomfort and to physical exertion. It was found that meat cutters using more knives were more likely to suffer from discomfort in the upper limbs, which is a risk for developing MSD. Copyright © 2016 Elsevier Ltd. All rights reserved.

Improvement in perception of image sharpness through the addition of noise and its relationship with memory texture

NASA Astrophysics Data System (ADS)

Wan, Xiazi; Kobayashi, Hiroyuki; Aoki, Naokazu

2015-03-01

In a preceding study, we investigated the effects of image noise on the perception of image sharpness using white noise, and one- and two-dimensional single-frequency sinusoidal patterns as stimuli. This study extends our preceding study by evaluating natural color images, rather than black-and-white patterns. The results showed that the effect of noise in improving image sharpness perception is more evident in blurred images than in sharp images. This is consistent with the results of the preceding study. In another preceding study, we proposed "memory texture" to explain the preferred granularity of images, as a concept similar to "memory color" for preferred color reproduction. We observed individual differences in type of memory texture for each object, that is, white or 1/f noise. This study discusses the relationship between improvement of sharpness perception by adding noise, and the memory texture, following its individual differences. We found that memory texture is one of the elements that affect sharpness perception.

Using Goal Setting, Task Clarification, and Feedback to Increase the Use of the Hands-Free Technique by Hospital Operating Room Staff

ERIC Educational Resources Information Center

Cunningham, Thomas R.; Austin, John

2007-01-01

We evaluated the effects of a behavioral treatment on the safe passing of sharp instruments using the hands-free technique among hospital operating room personnel during surgical procedures. Treatment consisted of participative goal setting, task clarification, and feedback. The average percentage of sharp instruments passed safely increased from…

Sharp Crater Rim with Dark Material and Boulders

NASA Image and Video Library

2012-03-02

This image from NASA Dawn spacecraft shows part of the sharp, fresh rim of a large crater on asteroid Vesta. There is some bright material slumping towards the center of this crater but this is mostly overshadowed by the dark material.

Sustained increase in hippocampal sharp-wave ripple activity during slow-wave sleep after learning

PubMed Central

Eschenko, Oxana; Ramadan, Wiâm; Mölle, Matthias; Born, Jan; Sara, Susan J.

2008-01-01

High-frequency oscillations, known as sharp-wave/ripple (SPW-R) complexes occurring in hippocampus during slow-wave sleep (SWS), have been proposed to promote synaptic plasticity necessary for memory consolidation. We recorded sleep for 3 h after rats were trained on an odor-reward association task. Learning resulted in an increased number SPW-Rs during the first hour of post-learning SWS. The magnitude of ripple events and their duration were also elevated for up to 2 h after the newly formed memory. Rats that did not learn the discrimination during the training session did not show any change in SPW-Rs. Successful retrieval from remote memory was likewise accompanied by an increase in SPW-R density and magnitude, relative to the previously recorded baseline, but the effects were much shorter lasting and did not include increases in ripple duration and amplitude. A short-lasting increase of ripple activity was also observed when rats were rewarded for performing a motor component of the task only. There were no increases in ripple activity after habituation to the experimental environment. These experiments show that the characteristics of hippocampal high-frequency oscillations during SWS are affected by prior behavioral experience. Associative learning induces robust and sustained (up to 2 h) changes in several SPW-R characteristics, while after retrieval from remote memory or performance of a well-trained procedural aspect of the task, only transient changes in ripple density were induced. PMID:18385477

Does cone beam CT actually ameliorate stab wound analysis in bone?

PubMed

Gaudio, D; Di Giancamillo, M; Gibelli, D; Galassi, A; Cerutti, E; Cattaneo, C

2014-01-01

This study aims at verifying the potential of a recent radiological technology, cone beam CT (CBCT), for the reproduction of digital 3D models which may allow the user to verify the inner morphology of sharp force wounds within the bone tissue. Several sharp force wounds were produced by both single and double cutting edge weapons on cancellous and cortical bone, and then acquired by cone beam CT scan. The lesions were analysed by different software (a DICOM file viewer and reverse engineering software). Results verified the limited performances of such technology for lesions made on cortical bone, whereas on cancellous bone reliable models were obtained, and the precise morphology within the bone tissues was visible. On the basis of such results, a method for differential diagnosis between cutmarks by sharp tools with a single and two cutting edges can be proposed. On the other hand, the metrical computerised analysis of lesions highlights a clear increase of error range for measurements under 3 mm. Metric data taken by different operators shows a strong dispersion (% relative standard deviation). This pilot study shows that the use of CBCT technology can improve the investigation of morphological stab wounds on cancellous bone. Conversely metric analysis of the lesions as well as morphological analysis of wound dimension under 3 mm do not seem to be reliable.

Hydrolase treatments help unravel the function of intervessel pits in xylem hydraulics.

PubMed

Dusotoit-Coucaud, Anaïs; Brunel, Nicole; Tixier, Aude; Cochard, Hervé; Herbette, Stéphane

2014-03-01

Intervessel pits are structures that play a key role in the efficiency and safety functions of xylem hydraulics. However, little is known about the components of the pit membrane (PM) and their role in hydraulic functions, especially in resistance to cavitation. We tested the effect of commercial chemicals including a cellulase, a hemicellulase, a pectolyase, a proteinase and DTT on xylem hydraulic properties: vulnerability to cavitation (VC) and conductance. The effects were tested on branch segments from Fagus sylvatica (where the effects on pit structure were analyzed using TEM) and Populus tremula. Cellulose hydrolysis resulted in a sharp increase in VC and a significant increase in conductance, related to complete breakdown of the PM. Pectin hydrolysis also induced a sharp increase in VC but with no effect on conductance or pit structure observable by TEM. The other treatments with hemicellulase, proteinase or DTT showed no effect. This study brings evidence that cellulose and pectins are critical components underpinning VC, and that PM components may play distinct roles in the xylem hydraulic safety and efficiency. © 2013 Scandinavian Plant Physiology Society.

Modelling of AlAs/GaAs interfacial structures using high-angle annular dark field (HAADF) image simulations.

PubMed

Robb, Paul D; Finnie, Michael; Craven, Alan J

2012-07-01

High angle annular dark field (HAADF) image simulations were performed on a series of AlAs/GaAs interfacial models using the frozen-phonon multislice method. Three general types of models were considered-perfect, vicinal/sawtooth and diffusion. These were chosen to demonstrate how HAADF image measurements are influenced by different interfacial structures in the technologically important III-V semiconductor system. For each model, interfacial sharpness was calculated as a function of depth and compared to aberration-corrected HAADF experiments of two types of AlAs/GaAs interfaces. The results show that the sharpness measured from HAADF imaging changes in a complicated manner with thickness for complex interfacial structures. For vicinal structures, it was revealed that the type of material that the probe projects through first of all has a significant effect on the measured sharpness. An increase in the vicinal angle was also shown to generate a wider interface in the random step model. The Moison diffusion model produced an increase in the interface width with depth which closely matched the experimental results of the AlAs-on-GaAs interface. In contrast, the interface width decreased as a function of depth in the linear diffusion model. Only in the case of the perfect model was it possible to ascertain the underlying structure directly from HAADF image analysis. Copyright © 2012 Elsevier B.V. All rights reserved.

Increased understanding of cellulose crystallinity

USDA-ARS?s Scientific Manuscript database

According to the International Union of Crystallography, “material is a crystal if it has essentially a sharp diffraction pattern. The word essentially means that most of the intensity of the diffraction is concentrated in relatively sharp Bragg peaks, besides the always present diffuse scattering.”...

Coordinated Interaction between Hippocampal Sharp-Wave Ripples and Anterior Cingulate Unit Activity

PubMed Central

2016-01-01

Hippocampal–cortical interaction during sleep promotes transformation of memory for long-term storage in the cortex. In particular, hippocampal sharp-wave ripple-associated neural activation is important for this transformation during slow-wave sleep. The anterior cingulate cortex (ACC) has been shown to be crucial for expression and likely storage of long-term memory. However, little is known about how ACC activity is influenced by hippocampal ripple activity during sleep. We report here about coordinated interactions between hippocampal ripple activity and ACC neural firings. By recording from the ACC and hippocampal CA1 simultaneously in mice, we found that almost all ACC neurons showed increased activity before hippocampal ripple activity; moreover, a subpopulation (17%) displayed a further activation immediately after ripple activity. This postripple activation of ACC neurons correlated positively with ripple amplitude, and the same neurons were excited upon electrical stimulation of the CA1. Interestingly, the preripple activation of ACC neurons was present during the sleep state, but not during the awake state. These results suggest intimate interactions between hippocampal sharp-wave ripples and ACC neurons in a state-dependent manner. Importantly, sharp-wave ripples and associated activation appear to regulate activity of a small population of ACC neurons, a process that may play a critical role in memory consolidation. SIGNIFICANCE STATEMENT The hippocampus communicates with the cortex for memory transformation. Memories of previous experiences become less dependent on the hippocampus and increasingly dependent on cortical areas, such as the anterior cingulate cortex (ACC). However, little evidence is available to directly support this hippocampus-to-cortex information transduction hypothesis of memory consolidation. Here we show that a subpopulation of ACC neurons becomes active just after hippocampal ripple activity, and that electrical stimulation of the hippocampus excites the same ACC neurons. In addition, the majority of ACC neurons are activated just before ripple activity during the sleep state, but not during the awake state. These results provide evidence supporting the hypothesis of hippocampus-to-cortex information flow for memory consolidation as well as reciprocal interaction between the hippocampus and the cortex. PMID:27733616

Computed tomography coronary stent imaging with iterative reconstruction: a trade-off study between medium kernel and sharp kernel.

PubMed

Zhou, Qijing; Jiang, Biao; Dong, Fei; Huang, Peiyu; Liu, Hongtao; Zhang, Minming

2014-01-01

To evaluate the improvement of iterative reconstruction in image space (IRIS) technique in computed tomographic (CT) coronary stent imaging with sharp kernel, and to make a trade-off analysis. Fifty-six patients with 105 stents were examined by 128-slice dual-source CT coronary angiography (CTCA). Images were reconstructed using standard filtered back projection (FBP) and IRIS with both medium kernel and sharp kernel applied. Image noise and the stent diameter were investigated. Image noise was measured both in background vessel and in-stent lumen as objective image evaluation. Image noise score and stent score were performed as subjective image evaluation. The CTCA images reconstructed with IRIS were associated with significant noise reduction compared to that of CTCA images reconstructed using FBP technique in both of background vessel and in-stent lumen (the background noise decreased by approximately 25.4% ± 8.2% in medium kernel (P

Sharps injuries in UK health care: a review of injury rates, viral transmission and potential efficacy of safety devices.

PubMed

Elder, Alexander; Paterson, Caron

2006-12-01

To review the literature on sharps injuries and occupational bloodborne virus transmission in health care in the UK and the worldwide evidence for injury prevention of sharps safety devices. Literature review by online database and Internet resource search. Twenty-four relevant publications were identified regarding UK reported sharps injury rates. UK studies showed as much as a 10-fold difference between injuries reported through standard reporting systems (0.78-5.15 per 100 person-years) and rates estimated from retrospective questionnaires of clinical populations (30-284 per 100 person-years). National surveillance data from England, Wales and Northern Ireland gives a rate of 1.43 known hepatitis C virus or human immunodeficiency virus (HIV) transmissions to health care workers per annum. When extrapolated, this suggests an approximate rate of 0.009 such viral transmissions per 1000 hospital beds per annum. Risk of infection from sources with no risk factors is extremely small (less than one in one million for HIV transmission based on Scottish data). Thirty-one studies on the efficacy of sharps safety devices showed evidence of a reduction in injuries, with the greatest reductions achieved by blunt suture needles and safety cannulae. Although injuries remain common, confirmed viral transmission in the UK has been relatively rare. The degree of under-reporting of sharps injuries may be as much as 10-fold. Safety-engineered devices are likely to be effective at injury reduction.

Rapid increase in lymphogranuloma venereum in men who have sex with men, United Kingdom, 2003 to September 2015.

PubMed

Childs, Tristan; Simms, Ian; Alexander, Sarah; Eastick, Kirstine; Hughes, Gwenda; Field, Nigel

2015-01-01

United Kingdom (UK) national data show a sharp increase in diagnoses of lymphogranuloma venereum (LGV) since 2012. Most cases are in men who have sex with men (MSM) living in London, with high rates of co-infection with HIV and other sexually transmitted infections. In light of these data, and the recent finding that one quarter of LGV infections may be asymptomatic, clinicians should be vigilant in testing for LGV, including in asymptomatic HIV-positive MSM.

The Case for Using Blunt-Tipped Lightning Rods as Strike Receptors.

NASA Astrophysics Data System (ADS)

Moore, C. B.; Aulich, G. D.; Rison, William

2003-07-01

Conventional lightning rods used in the United States have sharp tips, a practice derived from Benjamin Franklin's discovery of a means to obtain protection from lightning. However, the virtue of sharp tips for strike reception has never been established. An examination of the relevant physics shows that very strong electric fields are required above the tips of rods in order that they function as strike receptors but that the gradients of the field strength over sharp-tipped rods are so great that, at distances of a few millimeters, the local fields are often too weak for the development of upward-going streamers. In field tests, rods with rounded tips have been found to be better strike receptors than were nearby sharp-tipped rods.

Sharp Transition in the Lift Force of a Fluid Flowing Past Nonsymmetrical Obstacles: Evidence for a Lift Crisis in the Drag Crisis Regime.

PubMed

Bot, Patrick; Rabaud, Marc; Thomas, Goulven; Lombardi, Alessandro; Lebret, Charles

2016-12-02

Bluff bodies moving in a fluid experience a drag force which usually increases with velocity. However in a particular velocity range a drag crisis is observed, i.e., a sharp and strong decrease of the drag force. This counterintuitive result is well characterized for a sphere or a cylinder. Here we show that, for an object breaking the up-down symmetry, a lift crisis is observed simultaneously to the drag crisis. The term lift crisis refers to the fact that at constant incidence the time-averaged transverse force, which remains small or even negative at low velocity, transitions abruptly to large positive values above a critical flow velocity. This transition is characterized from direct force measurements as well as from change in the velocity field around the obstacle.

Relationship of intentional self-harm using sharp objects with depressive and dissociative tendencies in pre-adolescence-adolescence.

PubMed

Sho, Noriko; Oiji, Arata; Konno, Chizue; Toyohara, Koji; Minami, Tatsuya; Arai, Takashi; Seike, Yoji

2009-06-01

The objectives of the present study were to (i) evaluate the prevalence of children and adolescents who have engaged in intentional self-harm using a sharp object; and (ii) investigate the relationship between self-harm with sharp objects and depressive tendencies or dissociative tendencies. A total of 1938 students in grades 5-12 in Yokohama, Japan, were enrolled, and they completed anonymous self-report questionnaires including a question about intentional self-harm with a sharp object, the Depression Self-Rating Scale for Children (DSRSC) and the Adolescent Dissociative Experiences Scale (A-DES). The prevalence of self-harm using sharp object was 5.4% among male 5th-6th graders, 4.0% among female 5th-6th graders, 5.3% among male 7th-9th graders, 15.1% among female 7th-9th graders, 6.6% among male 10th-12th graders, and 9.6% among female 10th-12th graders. Categorical regression analysis showed that a small amount of variance in self-harm by sharp object was explained by DSRSC and A-DES scores. Self-harm with a sharp object was prevalent among pre-adolescents and adolescents and was associated with depressive and dissociative tendencies.

Intrinsic defect oriented visible region absorption in zinc oxide films

NASA Astrophysics Data System (ADS)

Rakhesh, V.; Shankar, Balakrishnan

2018-05-01

Zinc Oxide films were deposited on the glass substrate using vacuum arc sputtering technology. Films were prepared in oxygen ambience for 10mA and 15 mA deposition current separately. The UV-Visible spectroscopy of the samples showed that both samples possess sharp absorption near 3.5eV which is the characteristic band gap absorption energy of ZnO films. The absorption coefficient were calculated for the samples and the (αℎϑ)2 vs energy plot is drawn. The plot suggested that in addition to the sharp band edge absorption, the sample prepared at 10mA deposition current showed sharp absorption edge near 1.51eV and that at 15 mA showed absorption edge near 1.47eV. This refers to the presence of an intrinsic defect level which is likely to be deep in the band gap.

Automated Geometry assisted PEC for electron beam direct write nanolithography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ocola, Leonidas E.; Gosztola, David J.; Rosenmann, Daniel

Nanoscale geometry assisted proximity effect correction (NanoPEC) is demonstrated to improve PEC for nanoscale structures over standard PEC, in terms of feature sharpness for sub-100 nm structures. The method was implemented onto an existing commercially available PEC software. Plasmonic arrays of crosses were fabricated using regular PEC and NanoPEC, and optical absorbance was measured. Results confirm that the improved sharpness of the structures leads to increased sharpness in the optical absorbance spectrum features. We also demonstrated that this method of PEC is applicable to arbitrary shaped structures beyond crosses.

Condensation to a strongly correlated dark fluid of two dimensional dipolar excitons

NASA Astrophysics Data System (ADS)

Mazuz-Harpaz, Yotam; Cohen, Kobi; Rapaport, Ronen

2017-08-01

Recently we reported on the condensation of cold, electrostatically trapped dipolar excitons in GaAs bilayer heterostructure into a new, dense and dark collective phase. Here we analyze and discuss in detail the experimental findings and the emerging evident properties of this collective liquid-like phase. We show that the phase transition is characterized by a sharp increase of the number of non-emitting dipoles, by a clear contraction of the fluid spatial extent into the bottom of the parabolic-like trap, and by spectral narrowing. We extract the total density of the condensed phase which we find to be consistent with the expected density regime of a quantum liquid. We show that there are clear critical temperature and excitation power onsets for the phase transition and that as the power further increases above the critical power, the strong darkening is reduced down until no clear darkening is observed. At this point another transition appears which we interpret as a transition to a strongly repulsive yet correlated e-h plasma. Based on the experimental findings, we suggest that the physical mechanism that may be responsible for the transition is a dynamical final-state stimulation of the dipolar excitons to their dark spin states, which have a long lifetime and thus support the observed sharp increase in density. Further experiments and modeling will hopefully be able to unambiguously identify the physical mechanism behind these recent observations.

Optical properties of armchair (7, 7) single walled carbon nanotubes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gharbavi, K.; Badehian, H., E-mail: hojatbadehian@gmail.com

2015-07-15

Full potential linearized augmented plane waves method with the generalized gradient approximation for the exchange-correlation potential was applied to calculate the optical properties of (7, 7) single walled carbon nanotubes. The both x and z directions of the incident photons were applied to estimate optical gaps, dielectric function, electron energy loss spectroscopies, optical conductivity, optical extinction, optical refractive index and optical absorption coefficient. The results predict that dielectric function, ε (ω), is anisotropic since it has higher peaks along z-direction than x-direction. The static optical refractive constant were calculated about 1.4 (z-direction) and 1.1 (x- direction). Moreover, the electron energymore » loss spectroscopy showed a sharp π electron plasmon peaks at about 6 eV and 5 eV for z and x-directions respectively. The calculated reflection spectra show that directions perpendicular to the tube axis have further optical reflection. Moreover, z-direction indicates higher peaks at absorption spectra in low range energies. Totally, increasing the diameter of armchair carbon nanotubes cause the optical band gap, static optical refractive constant and optical reflectivity to decrease. On the other hand, increasing the diameter cause the optical absorption and the optical conductivity to increase. Moreover, the sharp peaks being illustrated at optical spectrum are related to the 1D structure of CNTs which confirm the accuracy of the calculations.« less

Fluid control mechanisms in weightlessness

NASA Technical Reports Server (NTRS)

Leach, Carolyn S.

1987-01-01

Experiments performed on Space Shuttle flights have emphasized study of the earliest effects of the cephalad fluid shift resulting from microgravity. Analysis of one subject's urine collected during flight showed that a sharp increase in antidiuretic hormone occurred within 2 h of launch, followed by an increase in cortisol excretion. Although this subject had symptoms of the space adaptation syndrome (SAS), inflight data from Spacelab missions suggested that these transient changes were not caused by SAS. Unpaired t-tests and Mann-Whitney tests showed that before and after flight, plasma thyroxine and urine osmolality were significantly higher in Shuttle crewmembers who exhibited more severe symptoms of SAS than in asymptomatic crewmembers.

The Impact of Different Levels of Adaptive Iterative Dose Reduction 3D on Image Quality of 320-Row Coronary CT Angiography: A Clinical Trial

PubMed Central

Feger, Sarah; Rief, Matthias; Zimmermann, Elke; Martus, Peter; Schuijf, Joanne Désirée; Blobel, Jörg; Richter, Felicitas; Dewey, Marc

2015-01-01

Purpose The aim of this study was the systematic image quality evaluation of coronary CT angiography (CTA), reconstructed with the 3 different levels of adaptive iterative dose reduction (AIDR 3D) and compared to filtered back projection (FBP) with quantum denoising software (QDS). Methods Standard-dose CTA raw data of 30 patients with mean radiation dose of 3.2 ± 2.6 mSv were reconstructed using AIDR 3D mild, standard, strong and compared to FBP/QDS. Objective image quality comparison (signal, noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), contour sharpness) was performed using 21 measurement points per patient, including measurements in each coronary artery from proximal to distal. Results Objective image quality parameters improved with increasing levels of AIDR 3D. Noise was lowest in AIDR 3D strong (p≤0.001 at 20/21 measurement points; compared with FBP/QDS). Signal and contour sharpness analysis showed no significant difference between the reconstruction algorithms for most measurement points. Best coronary SNR and CNR were achieved with AIDR 3D strong. No loss of SNR or CNR in distal segments was seen with AIDR 3D as compared to FBP. Conclusions On standard-dose coronary CTA images, AIDR 3D strong showed higher objective image quality than FBP/QDS without reducing contour sharpness. Trial Registration Clinicaltrials.gov NCT00967876 PMID:25945924

Objective assessment of knife sharpness over a working day cutting meat.

PubMed

Savescu, Adriana; Cuny-Guerrier, Aude; Wild, Pascal; Reno, Gilles; Aublet-Cuvelier, Agnès; Claudon, Laurent

2018-04-01

Knife sharpness is one of multiple factors involved in musculoskeletal disorders in industrial meat cutting. The aim of this study was to objectively evaluate, in real working situations, how knife sharpness changed over a working day cutting meat, and to analyse the impact of sharpening, steeling and meat-cutting activities on these variations. Twenty-two meat-cutting workers from three different companies participated in the study. The methods included measurements of knife sharpness in relation to real work situations and consideration of the way meat-cutting and sharpening operations were organised. Results showed that the type of meat-cutting activities, the steeling strategy adopted by the worker, including the types of tool used, and the overall organisation of the sharpening task all had a significant influence on how knife sharpness evolved over a 2-h period and over an entire working day. To improve MSD prevention, sharpening and steeling operations should not be considered as independent activities, but taken into account as a continuity of working actions. Appropriate assessment of knife sharpness by meat cutters affects how they organise meat-cutting and sharpening tasks. Copyright © 2017 Elsevier Ltd. All rights reserved.

Artificial intelligence for turboprop engine maintenance

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-01-01

Long-term maintenance operations, causing the unit to out of action, may seem economical - but they result in reduced operating readiness. Offsetting that concern, careless, hurried maintenance reduces margins of safety and reliability. Any tool that improves maintenance without causing a sharp increase in cost is valuable. Artificial intelligence (AI) is one of the tools. Expert system and neural networks are two different areas of AI that show promise for turboprop engine maintenance.

Self-Regulating Shock Absorber

NASA Technical Reports Server (NTRS)

Wesselski, Clarence J.

1995-01-01

Mechanical shock absorber keeps frictional damping force within tolerable limit. Its damping force does not increase with coefficient of friction between energy-absorbing components; rather, frictional damping force varies only slightly. Relatively insensitive to manufacturing variations and environmental conditions altering friction. Does not exhibit high breakaway friction and consequent sharp increase followed by sharp decrease in damping force at beginning of stroking. Damping force in absorber does not vary appreciably with speed of stroking. In addition, not vulnerable to leakage of hydraulic fluid.

Metal-Insulator Transition in W-doped VO2 Nanowires

NASA Astrophysics Data System (ADS)

Long, Gen; Parry, James; Whittaker, Luisa; Banerjee, Sarbajit; Zeng, Hao

2010-03-01

We report a systematic study of the metal-insulator transition in W-doped VO2 nanowires. Magnetic susceptibility were measured for a bulk amount of VO2 nanowire powder. The susceptibility shows a sharp drop with decreasing temperature corresponding to the metal-insulator transition. The transition shows large temperature hysteresis for cooling and heating. With increasing doping concentration, the transition temperatures decreases systematically from 320 K to 275K. Charge transport measurements on the same nanowires showed similar behavior. XRD and TEM measurements were taken to further determine the structure of the materials in study.

Chiral tunneling in gated inversion symmetric Weyl semimetal.

PubMed

Bai, Chunxu; Yang, Yanling; Chang, Kai

2016-02-18

Based on the chirality-resolved transfer-matrix method, we evaluate the chiral transport tunneling through Weyl semimetal multi-barrier structures created by periodic gates. It is shown that, in sharp contrast to the cases of three dimensional normal semimetals, the tunneling coefficient as a function of incident angle shows a strong anisotropic behavior. Importantly, the tunneling coefficients display an interesting periodic oscillation as a function of the crystallographic angle of the structures. With the increasement of the barriers, the tunneling current shows a Fabry-Perot type interferences. For superlattice structures, the fancy miniband effect has been revealed. Our results show that the angular dependence of the first bandgap can be reduced into a Lorentz formula. The disorder suppresses the oscillation of the tunneling conductance, but would not affect its average amplitude. This is in sharp contrast to that in multi-barrier conventional semiconductor structures. Moreover, numerical results for the dependence of the angularly averaged conductance on the incident energy and the structure parameters are presented and contrasted with those in two dimensional relativistic materials. Our work suggests that the gated Weyl semimetal opens a possible new route to access to new type nanoelectronic device.

Chiral tunneling in gated inversion symmetric Weyl semimetal

PubMed Central

Bai, Chunxu; Yang, Yanling; Chang, Kai

2016-01-01

Based on the chirality-resolved transfer-matrix method, we evaluate the chiral transport tunneling through Weyl semimetal multi-barrier structures created by periodic gates. It is shown that, in sharp contrast to the cases of three dimensional normal semimetals, the tunneling coefficient as a function of incident angle shows a strong anisotropic behavior. Importantly, the tunneling coefficients display an interesting periodic oscillation as a function of the crystallographic angle of the structures. With the increasement of the barriers, the tunneling current shows a Fabry-Perot type interferences. For superlattice structures, the fancy miniband effect has been revealed. Our results show that the angular dependence of the first bandgap can be reduced into a Lorentz formula. The disorder suppresses the oscillation of the tunneling conductance, but would not affect its average amplitude. This is in sharp contrast to that in multi-barrier conventional semiconductor structures. Moreover, numerical results for the dependence of the angularly averaged conductance on the incident energy and the structure parameters are presented and contrasted with those in two dimensional relativistic materials. Our work suggests that the gated Weyl semimetal opens a possible new route to access to new type nanoelectronic device. PMID:26888491

The effect of high-efficiency particulate air respirator design on occupational health: a pilot study balancing risks in the real world.

PubMed

Eck, E K; Vannier, A

1997-02-01

To quantify specific factors believed to increase healthcare worker (HCW) risk for contaminated sharps injuries (eg, visibility, communication, and range of motion); to quantify the degree to which respirators of various designs impacted those same factors; and to assess HCW opinions about the suitability of selected respirators with respect to patient care and user compliance criteria. Sharps injury data from seven hospitals were analyzed to determine the potential contribution of visibility, communication, and range of motion to reported injuries. Healthcare workers representing various clinical specialties and physical characteristics were examined at baseline and while wearing five different respirators to quantify the impact of respirator design on visibility, communication, and range of motion. Healthcare workers were interviewed and completed a survey assessing each respirator. Hospital and ambulatory-care settings. Population-based and convenience sample. Communication, visibility, and range of motion were found to affect contaminated sharps injuries significantly. Selected high-efficiency particulate air (HEPA) respirators were found to have a negative impact on each of these variables. Healthcare workers involved in the study also reported compliance criteria problems with selected HEPA respirators, which may effect implementation of respiratory precautions adversely. Current HEPA respirators, because of their design, potentially increase the risk of bloodborne pathogen exposure through sharps injuries. We conclude that mandating respirators without regard to the potential impact of their design to the sharps injuries may be counterproductive to HCW safety, because they may increase, rather than decrease, overall occupational risk to HCWs.

How sharp is sharp? Towards quantification of the sharpness and penetration ability of kitchen knives used in stabbings.

PubMed

Hainsworth, S V; Delaney, R J; Rutty, G N

2008-07-01

Stabbing is the most common method for violent death in the UK. As part of their investigation, forensic pathologists are commonly asked to estimate or quantify the degree of force required to create a wound. The force required to penetrate the skin and body by a knife is a complex function of the sharpness of the knife, the area of the body and alignment with cleavage lines of the skin, the angle of attack and the relative movement of the person stabbing relative to the victim being stabbed. This makes it difficult for the forensic pathologist to give an objective answer to the question; hence, subjective estimations are often used. One area where some degree of quantification is more tractable is in assessing how sharp an implement (particularly a knife) is. This paper presents results of a systematic study of how the different aspects of knife geometry influence sharpness and presents a simple test for assessing knife sharpness using drop testing. The results show that the radius of the blunt edge at the tip is important for controlling the penetration ability of a kitchen knife. Using high-speed video, it also gives insight into the mechanism of knife penetration into the skin. The results of the study will aid pathologists in giving a more informed answer to the question of the degree of force used in stabbing.

A Unified Dynamic Model for Learning, Replay, and Sharp-Wave/Ripples.

PubMed

Jahnke, Sven; Timme, Marc; Memmesheimer, Raoul-Martin

2015-12-09

Hippocampal activity is fundamental for episodic memory formation and consolidation. During phases of rest and sleep, it exhibits sharp-wave/ripple (SPW/R) complexes, which are short episodes of increased activity with superimposed high-frequency oscillations. Simultaneously, spike sequences reflecting previous behavior, such as traversed trajectories in space, are replayed. Whereas these phenomena are thought to be crucial for the formation and consolidation of episodic memory, their neurophysiological mechanisms are not well understood. Here we present a unified model showing how experience may be stored and thereafter replayed in association with SPW/Rs. We propose that replay and SPW/Rs are tightly interconnected as they mutually generate and support each other. The underlying mechanism is based on the nonlinear dendritic computation attributable to dendritic sodium spikes that have been prominently found in the hippocampal regions CA1 and CA3, where SPW/Rs and replay are also generated. Besides assigning SPW/Rs a crucial role for replay and thus memory processing, the proposed mechanism also explains their characteristic features, such as the oscillation frequency and the overall wave form. The results shed a new light on the dynamical aspects of hippocampal circuit learning. During phases of rest and sleep, the hippocampus, the "memory center" of the brain, generates intermittent patterns of strongly increased overall activity with high-frequency oscillations, the so-called sharp-wave/ripples. We investigate their role in learning and memory processing. They occur together with replay of activity sequences reflecting previous behavior. Developing a unifying computational model, we propose that both phenomena are tightly linked, by mutually generating and supporting each other. The underlying mechanism depends on nonlinear amplification of synchronous inputs that has been prominently found in the hippocampus. Besides assigning sharp-wave/ripples a crucial role for replay generation and thus memory processing, the proposed mechanism also explains their characteristic features, such as the oscillation frequency and the overall wave form. Copyright © 2015 the authors 0270-6474/15/3516236-23$15.00/0.

The evolution of the Brewer-Dobson Circulation from 1960-2100 in simulations with the Chemistry Climate Model EMAC

NASA Astrophysics Data System (ADS)

Oberländer, Sophie; Langematz, Ulrike; Kubin, Anne; Abalichin, Janna; Meul, Stefanie; Jöckel, Patrick; Brühl, Christoph

2010-05-01

First results of research performed within the new DFG Research Unit Stratospheric Change and its Role for Climate Prediction (SHARP) will be presented. SHARP investigates past and future changes in stratospheric dynamics and composition to improve the understanding of global climate change and the accuracy of climate change predictions. SHARP combines the efforts of eight German research institutes and expertise in state-of-the-art climate modelling and observations. Within the scope of the scientific sub-project SHARP-BDC (Brewer-Dobson-Circulation) the past and future evolution of the BDC in an atmosphere with changing composition will be analysed. Radiosonde data show an annual mean cooling of the tropical lower stratosphere over the past few decades (Thompson and Solomon, 2005). Several independent model simulations indicate an acceleration of the BDC due to higher greenhouse gas (GHG) concentrations with direct impact on the exchange of air masses between the troposphere and stratosphere (e.g., Butchart et al, 2006). In contrast, from balloon-born measurements no significant acceleration in the BDC could be identified (Engel et al, 2008). This disagreement between observations and model analyses motivates further studies. For the future, expected changes in planetary wave generation and propagation in an atmosphere with increasing GHG concentrations are a major source of uncertainty for predicting future levels of stratospheric composition. To analyse and interpret the past and future evolution of the BDC, results from a transient multi-decadal simulation with the Chemistry-Climate Model (CCM) EMAC will be presented. The model has been integrated from 1960 to 2100 following the SCN2d scenario recommendations of the SPARC CCMVal initiative for the temporal evolution of GHGs, ozone depleting substances and sea surface temperatures as well as sea ice. The role of increasing GHG concentrations for the BDC will be assessed by comparing the SCN2d-results with a ‘non-climate change' (NCC) simulation, in which greenhouse gases have been kept fixed at their 1960 concentrations.

Accurate simulation of backscattering spectra in the presence of sharp resonances

NASA Astrophysics Data System (ADS)

Barradas, N. P.; Alves, E.; Jeynes, C.; Tosaki, M.

2006-06-01

In elastic backscattering spectrometry, the shape of the observed spectrum due to resonances in the nuclear scattering cross-section is influenced by many factors. If the energy spread of the beam before interaction is larger than the resonance width, then a simple convolution with the energy spread on exit and with the detection system resolution will lead to a calculated spectrum with a resonance much sharper than the observed signal. Also, the yield from a thin layer will not be calculated accurately. We have developed an algorithm for the accurate simulation of backscattering spectra in the presence of sharp resonances. Albeit approximate, the algorithm leads to dramatic improvements in the quality and accuracy of the simulations. It is simple to implement and leads to only small increases of the calculation time, being thus suitable for routine data analysis. We show different experimental examples, including samples with roughness and porosity.

Combustion Noise at Elevated Pressures in a Liquid-Fueled Premixed Combustor

NASA Technical Reports Server (NTRS)

Darling, Douglas; Radhakrishnan, Krishnan; Oyediran, Ayo

1997-01-01

Noise generated in gas turbine combustors can exist in several forms-broadband noise, sharp resonant peaks, and regular or intermittent nonlinear pulsing. In the present study, dynamic pressure measurements were made in several JP-5-fueled combustor configurations, at various mean pressures and temperatures. The fluctuating pressure was measured at mean pressures from 6 to 14 atm and inlet temperatures from 550 K to 850 K. The goal of the present work was to study the effect of changes in mean flow conditions on combustor noise: both broadband noise and sharp tones were considered. In general, the shape of the broadband noise spectrum was consistent from one configuration to another. The shape of the spectrum was influenced by the acoustic filtering of the combustion zone. This filtering ensured the basic consistency of the spectra. In general, the trends in broadband noise observed at low mean pressures were also seen at high mean pressures; that is, the total sound level decreased with both increasing equivalence ratio and increasing inlet temperature. The combustor configurations without a central pilot experienced higher broadband noise levels and were more susceptible to narrow peak resonances than configurations with a central pilot. The sharp peaks were more sensitive to the mean flow than was the broadband noise, and the effects were not always the same. In some situations, increasing the equivalence ratio made the sharp peaks grow, while at other conditions, increasing the equivalence ratio made the sharp peaks shrink. Thus, it was difficult to predict when resonances would occur; however, they were reproducible. Acoustic coupling between the upstream and downstream regions of the combustor may play a role in the sharp-peaked oscillations. Noise was also observed near lean blow out. As with other types of noise, lean blow out noise was affected by the combustion chamber acoustics, which apparently maintains the fluctuations at a uniform frequency. However, the actual conditions when this type of noise was experienced appeared to simply follow the lean blow out limit as it varied with mean temperature and pressure.

The effects of adrenalectomy and corticsteroid injection on the fibrinolytic activity of complex heparin compounds in the blood during immobilization

NASA Technical Reports Server (NTRS)

Kudryashov, B. A.; Lomovskaya, E. G.; Shapiro, F. B.; Lyapina, L. Y.

1980-01-01

Total non-enzymatic fibrinolytic activity in the blood of rats increased three times in response to stress caused by 30 minute immobilization, and the activity of epinephrine-heparin complex increased nine times. In adrenalectomized animals, which showed a weak response to the same stress, intraperitoneal injection of hydrocortisone 30 minutes prior to immobilization normalized the response. Obtained results indicate that adrenalectomy leads to sharp reduction of heparin complexing with thromogenic proteins and epinephrine, while substitution therapy with hydrocortisone restores anticoagulation system function.

Characterization of Organic Materials in the Xenolithic Clasts in Sharps (H3.4) Meteorite Using Micro-Raman Spectroscopy

NASA Technical Reports Server (NTRS)

Chan, Q. H. S.; Zolensky, M. E.; Bodnar, R. J.; Kebukawa, Y.

2015-01-01

Graphitization of carbon is an irreversible process which alters the structure of graphitic materials in response to the increase in metamorphic grade (temperature and/or pressure). Carbonaceous materials offer a reliable geothermometer as their Raman spectra change systematically with increasing metamorphic grade. In this study, we identified carbonaceous materials in the xenolithic clasts in Sharps and interpreted their metamorphic history by revealing the structural organization (order) of the polyaromatic organic phases using micro-Raman spectroscopy.

Characterization of Organic Materials in the Xenolithic Clasts in Sharps (H3.4) Meteorite Using Microraman Spectroscopy

NASA Technical Reports Server (NTRS)

Chan, Q. H. S.; Zolensky, M. E.; Bodnar, R. J.; Kebukawa, Y.

2015-01-01

Graphitization of carbon is an irreversible process which alters the structure of graphitic materials in response to the increase in metamorphic grade (temperature and/or pressure). Carbonaceous materials offer a reliable geothermometer as their Raman spectra change systematically with increasing metamorphic grade [1-3]. In this study, we identified carbonaceous materials in the xenolithic clasts in Sharps and interpreted their metamorphic history by revealing the structural organization (order) of the polyaromatic organic phases using µ-Raman spectroscopy.

Windrow composting mitigated CH4 emissions: characterization of methanogenic and methanotrophic communities in manure management.

PubMed

Chen, Ruirui; Wang, Yiming; Wei, Shiping; Wang, Wei; Lin, Xiangui

2014-12-01

With increasing livestock breeding, methane (CH4 ) emissions from manure management will increasingly contribute more to atmospheric CH4 concentration. The dynamics of methanogens and methanotrophs have not yet been studied in the manure environment. The current study combines surface CH4 emissions with methanogenic and methanotrophic community analyses from two management practices, windrow composting (WCOM) and solid storage (SSTO). Our results showed that there was an c. 50% reduction of CH4 emissions with WCOM compared with SSTO over a 50-day period. A sharp decrease in the quantities of both methanogens and methanotrophs in WCOM suggested that CH4 mitigation was mainly due to decreased CH4 production rather than increased CH4 oxidation. Pyrosequencing analysis demonstrated that aeration caused a clear shift of dominant methanogens in the manure, with specifically a significant decrease in Methanosarcina and increase in Methanobrevibacter. The composition of methanogenic community was influenced by manure management and regulated CH4 production. A sharp increase in the quantity of methanotrophs in SSTO suggested that microbial CH4 oxidation is an important sink for the CH4 produced. The increased abundance of Methylococcaceae in SSTO suggested that Type I methanotrophs have an advantage in CH4 oxidation in occupying niches under low CH4 and high O2 conditions. © 2014 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

Conservative sharp debridement: the professional and legal issues.

PubMed

Ashworth, Jenny; Chivers, Marc

2002-06-01

In recent years there has been much debate over the use of conservative sharp debridement in the treatment of certain wound types. Here it is discussed in relation to increasing the speed of wound healing in slow-to-heal wounds. The authors examine education and skill competence in relation to the professional's duty of care to patients with wounds.

Cannula Versus Sharp Needle for Placement of Soft Tissue Fillers: An Observational Cadaver Study.

PubMed

van Loghem, Jani A J; Humzah, Dalvi; Kerscher, Martina

2017-12-13

Soft-tissue fillers have become important products for facial rejuvenation. Deep fat compartments and facial bones lose volume during the natural aging process. For the most natural-looking results, deep volumetric injections at strategic sites are therefore preferred. Supraperiosteal placement is performed with a sharp needle or a non-traumatic cannula. The primary objective was to determine whether there is a difference in precision between supraperiosteal placement with a sharp needle compared with a non-traumatic cannula in cadaver specimens. A secondary objective was to analyze the safety profiles of both injection techniques. Cadaver heads were injected with dye material and soft-tissue fillers at multiple aesthetic facial sites on the supraperiosteum and subsequently dissected for observation of dye and filler placement. The non-traumatic cannula technique resulted in product being confined to the deep anatomic layers. In contrast, with the sharp needle technique, material was placed in multiple anatomic layers, from the periosteum to more superficial skin layers. For both techniques results were consistent for all facial sites. Although direct extrapolation from cadavers to the in vivo situation cannot be made, cannulae showed more precision in placement of product. With the sharp needle, the material was injected on the periosteum, and then migrated in a retrograde direction along the trajectory of the needle path, ending up in multiple anatomic layers. The sharp needle technique also showed a higher complication risk with intra-arterial injection occurring, even though the needle tip was positioned on the periosteum and the product was injected with the needle in constant contact with the periosteum. © 2016 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com

Elemental abundance analyses with DAO spectrograms. VII - The late normal B stars Pi Ceti, 134 Tauri, 21 Aquilae, and Nu Capricorni and the use of RETICON spectra

NASA Astrophysics Data System (ADS)

Adelman, Saul J.

1991-09-01

This paper presents elemental abundance analyses of sharp-lined normal late B stars. These stars exhibit mostly near-solar abundances, but each star also shows a few abundances which are a factor of 2 less than solar. The coadded photographic spectrograms are supplemented with Reticon data. A comparison of 261 equivalent widths on 2.4 A/mm spectra of sharp-lined B and A stars shows that the Reticon equivalent widths are about 95 percent of the coadded equivalent mean. The H-gamma profiles of the coadded and Reticon spectra for eight sharp-lined stars show generally good agreement. The generally high quality of the coadded data produced from 10 or more spectrograms is confirmed using the REDUCE graphics-oriented computed reduction code. For five stars, metal lines which fall in the gap between the U and V plates are analyzed using Reticon data.

Elemental abundance analyses with DAO spectrograms. VII - The late normal B stars Pi Ceti, 134 Tauri, 21 Aquilae, and Nu Capricorni and the use of Reticon spectra

NASA Technical Reports Server (NTRS)

Adelman, Saul J.

1991-01-01

This paper presents elemental abundance analyses of sharp-lined normal late B stars. These stars exhibit mostly near-solar abundances, but each star also shows a few abundances which are a factor of 2 less than solar. The coadded photographic spectrograms are supplemented with Reticon data. A comparison of 261 equivalent widths on 2.4 A/mm spectra of sharp-lined B and A stars shows that the Reticon equivalent widths are about 95 percent of the coadded equivalent mean. The H-gamma profiles of the coadded and Reticon spectra for eight sharp-lined stars show generally good agreement. The generally high quality of the coadded data produced from 10 or more spectrograms is confirmed using the REDUCE graphics-oriented computed reduction code. For five stars, metal lines which fall in the gap between the U and V plates are analyzed using Reticon data.

Four cases of type 1 diabetes mellitus showing sharp serum transaminase increases and hepatomegaly due to glycogenic hepatopathy.

PubMed

Ikarashi, Yuichi; Kogiso, Tomomi; Hashimoto, Etsuko; Yamamoto, Kuniko; Kodama, Kazuhisa; Taniai, Makiko; Torii, Nobuyuki; Takaike, Hiroko; Uchigata, Yasuko; Tokushige, Katsutoshi

2017-03-01

Poorly controlled diabetes mellitus (DM) patients sometimes show serum transaminase elevations due to steatohepatitis. However, we experienced four cases with type 1 DM with sharp elevations in serum transaminases that could not be explained by steatohepatitis alone and showed bright liver. They were diagnosed with glycogenic hepatopathy (GH) clinicopathologically. The four patients had a median age of 22.5 years (range, 19-29 years) and 12.5 (4-15)-year histories of type 1 DM and showed marked increases in serum transaminases (aspartate aminotransferase, 698 U/L [469-2763 U/L]; alanine transaminase, 255 U/L [216-956 U/L]). Diabetes mellitus control was poor and hemoglobin A1c was 12.7% (11-16.5%). Three cases had a past history of diabetic ketoacidosis. Hepatomegaly and hyperdense liver were seen on computed tomography scans. Magnetic resonance imaging showed low intensity in T2-weighted images. The pathological findings revealed pale and swollen hepatocytes and glycogenated nuclei. The architecture of the liver was preserved, and steatosis and fibrosis were mild. The cytoplasm of hepatocytes stained densely positive with periodic acid-Schiff, and the positive staining disappeared after diastase digestion, suggesting glycogen deposition. No other cause of hepatitis was evident, and the diagnosis was GH. Elevated transaminases improved within 1 month with good glycemic control. Transaminase elevations were observed several times in three cases with poor glycemic control. Glycogenic hepatopathy is rare, but extremely high serum elevations of transaminases are important to identify clinically. Despite showing a good clinical course in general, GH sometimes recurs and requires strict glycemic control. Clinicians should be aware of and recognize GH when dealing with uncontrolled DM patients. © 2016 The Japan Society of Hepatology.

Correlation Between Pre-annealing Temperature and {110}<001> Annealing Texture in C- and Al-Free Fe-3 Pct Si-0.1 Pct Mn-0.002 Pct S Electrical Steel

NASA Astrophysics Data System (ADS)

Oh, Eun Jee; Heo, Nam Hoe; Koo, Yang Mo

2017-06-01

In C- and Al-free electrical steel, the increase in primary grain size with increasing pre-annealing temperature causes the transition in annealing texture after final annealing from {110} + {100} to {110}. The strip pre-annealed at 1073 K (800 °C) shows a low magnetic induction B8(T) of 1.784 T after final annealing. The strip pre-annealed at 1223 K (950 °C) shows a sharp {110}<001> Goss texture, producing a high magnetic induction B8(T) of 1.914 T comparable to that of the conventional electrical steels.

Steep, Transient Density Gradients in the Martian Ionosphere Similar to the Ionopause at Venus

NASA Astrophysics Data System (ADS)

Duru, Firdevs; Gurnett, Donald; Frahm, Rudy; Winningham, D. L.; Morgan, David; Howes, Gregory

Using Mars Advanced Radar for Subsurface and Ionospheric Sounding (MARSIS) on the Mars Express (MEX) spacecraft, the electron density can be measured by two methods: from the excitation of local plasma oscillations and from remote sounding. A study of the local electron density versus time for 1664 orbits revealed that in 132 orbits very sharp gradients in the electron density occurred that are similar to the ionopause boundary commonly observed at Venus. In 40 of these cases, remote sounding data have also confirmed identical locations of steep ionopause-like density gradients. Measurements from the Analyzer of Space Plasma and Energetic Atoms (ASPERA-3) Electron Spectrometer (ELS) and Ion Mass Analyzer (IMA) instruments (also on Mars Express) verify that these sharp decreases in the electron density occur somewhere between the end of the region where ionospheric photoelectrons are dominant and the magnetosheath. Combined studies of the two experiments reveal that the steep density gradients define a boundary where the magnetic fields change from open to closed. This study shows that, although the individual cases are from a wide range of altitudes, the average altitude of the boundary as a function of solar zenith angle is almost constant. The average altitude is approximately 500 km up to solar zenith angles of 60o, after which it shows a slight increase. The average thickness of the boundary is about 22 km according to remote sounding measurements. The altitude of the steep gradients shows an increase at locations with strong crustal magnetic fields.

The stratigraphy and evolution of lower Mount Sharp from spectral, morphological, and thermophysical orbital data sets.

PubMed

Fraeman, A A; Ehlmann, B L; Arvidson, R E; Edwards, C S; Grotzinger, J P; Milliken, R E; Quinn, D P; Rice, M S

2016-09-01

We have developed a refined geologic map and stratigraphy for lower Mount Sharp using coordinated analyses of new spectral, thermophysical, and morphologic orbital data products. The Mount Sharp group consists of seven relatively planar units delineated by differences in texture, mineralogy, and thermophysical properties. These units are (1-3) three spatially adjacent units in the Murray formation which contain a variety of secondary phases and are distinguishable by thermal inertia and albedo differences, (4) a phyllosilicate-bearing unit, (5) a hematite-capped ridge unit, (6) a unit associated with material having a strongly sloped spectral signature at visible near-infrared wavelengths, and (7) a layered sulfate unit. The Siccar Point group consists of the Stimson formation and two additional units that unconformably overlie the Mount Sharp group. All Siccar Point group units are distinguished by higher thermal inertia values and record a period of substantial deposition and exhumation that followed the deposition and exhumation of the Mount Sharp group. Several spatially extensive silica deposits associated with veins and fractures show that late-stage silica enrichment within lower Mount Sharp was pervasive. At least two laterally extensive hematitic deposits are present at different stratigraphic intervals, and both are geometrically conformable with lower Mount Sharp strata. The occurrence of hematite at multiple stratigraphic horizons suggests redox interfaces were widespread in space and/or in time, and future measurements by the Mars Science Laboratory Curiosity rover will provide further insights into the depositional settings of these and other mineral phases.

Lacosamide and Levetiracetam Have No Effect on Sharp-Wave Ripple Rate.

PubMed

Kudlacek, Jan; Chvojka, Jan; Posusta, Antonin; Kovacova, Lubica; Hong, Seung Bong; Weiss, Shennan; Volna, Kamila; Marusic, Petr; Otahal, Jakub; Jiruska, Premysl

2017-01-01

Pathological high-frequency oscillations are a novel marker used to improve the delineation of epileptogenic tissue and, hence, the outcome of epilepsy surgery. Their practical clinical utilization is curtailed by the inability to discriminate them from physiological oscillations due to frequency overlap. Although it is well documented that pathological HFOs are suppressed by antiepileptic drugs (AEDs), the effect of AEDs on normal HFOs is not well known. In this experimental study, we have explored whether physiological HFOs (sharp-wave ripples) of hippocampal origin respond to AED treatment. The results show that application of a single dose of levetiracetam or lacosamide does not reduce the rate of sharp-wave ripples. In addition, it seems that these new generation drugs do not negatively affect the cellular and network mechanisms involved in sharp-wave ripple generation, which may provide a plausible explanation for the absence of significant negative effects on cognitive functions of these drugs, particularly on memory.

Measurements of lightning rod responses to nearby strikes

NASA Astrophysics Data System (ADS)

Moore, C. B.; Aulich, G. D.; Rison, W.

2000-05-01

Following Benjamin Franklin's invention of the lightning rod, based on his discovery that electrified objects could be discharged by approaching them with a metal needle in hand, conventional lightning rods in the U.S. have had sharp tips. In recent years, the role of the sharp tip in causing a lightning rod to act as a strike receptor has been questioned leading to experiments in which pairs of various sharp-tipped and blunt rods have been exposed beneath thunderclouds to determine the better strike receptor. After seven years of tests, none of the sharp Franklin rods or of the so-called “early streamer emitters” has been struck, but 12 blunt rods with tip diameters ranging from 12.7 mm to 25.4 mm have taken strikes. Our field experiments and our analyses indicate that the strike-reception probabilities of Franklin's rods are greatly increased when their tips are made moderately blunt.

The effect of climate variability on urinary stone attacks: increased incidence associated with temperature over 18 °C: a population-based study.

PubMed

Park, Hyoung Keun; Bae, Sang Rak; Kim, Satbyul E; Choi, Woo Suk; Paick, Sung Hyun; Ho, Kim; Kim, Hyeong Gon; Lho, Yong Soo

2015-02-01

The aim of this study was to evaluate the effect of seasonal variation and climate parameters on urinary tract stone attack and investigate whether stone attack is increased sharply at a specific point. Nationwide data of total urinary tract stone attack numbers per month between January 2006 and December 2010 were obtained from the Korean Health Insurance Review and Assessment Service. The effects of climatic factors on monthly urinary stone attack were assessed using auto-regressive integrated moving average (ARIMA) regression method. A total of 1,702,913 stone attack cases were identified. Mean monthly and monthly average daily urinary stone attack cases were 28,382 ± 2,760 and 933 ± 85, respectively. The stone attack showed seasonal trends of sharp incline in June, a peak plateau from July to September, and a sharp decline after September. The correlation analysis showed that ambient temperature (r = 0.557, p < 0.001) and relative humidity (r = 0.513, p < 0.001) were significantly associated with urinary stone attack cases. However, after adjustment for trends and seasonality, ambient temperature was the only climate factor associated with the stone attack cases in ARIMA regression test (p = 0.04). Threshold temperature was estimated as 18.4 °C. Risk of urinary stone attack significantly increases 1.71% (1.02-2.41 %, 95% confidence intervals) with a 1 °C increase of ambient temperature above the threshold point. In conclusion, monthly urinary stone attack cases were changed according to seasonal variation. Among the climates variables, only temperature had consistent association with stone attack and when the temperature is over 18.4 °C, urinary stone attack would be increased sharply.

Aerosol-driven increase in Arctic sea ice over the middle of the twentieth century

NASA Astrophysics Data System (ADS)

Gagné, Marie-Ève; Fyfe, John C.; Gillett, Nathan P.; Polyakov, Igor V.; Flato, Gregory M.

2017-07-01

Updated observational data sets without climatological infilling show that there was an increase in sea ice concentration in the eastern Arctic between 1950 and 1975, contrary to earlier climatology infilled observational data sets that show weak interannual variations during that time period. We here present climate model simulations showing that this observed sea ice concentration increase was primarily a consequence of cooling induced by increasing anthropogenic aerosols and natural forcing. Indeed, sulphur dioxide emissions, which lead to the formation of sulphate aerosols, peaked around 1980 causing a sharp increase in the burden of sulphate between the 1950s and 1970s; but since 1980, the burden has dropped. Our climate model simulations show that the cooling contribution of aerosols offset the warming effect of increasing greenhouse gases over the midtwentieth century resulting in the expansion of the Arctic sea ice cover. These results challenge the perception that Arctic sea ice extent was unperturbed by human influence until the 1970s, suggesting instead that it exhibited earlier forced multidecadal variations, with implications for our understanding of impacts and adaptation in human and natural Arctic systems.

Shear banding, discontinuous shear thickening, and rheological phase transitions in athermally sheared frictionless disks

NASA Astrophysics Data System (ADS)

Vâgberg, Daniel; Olsson, Peter; Teitel, S.

2017-05-01

We report on numerical simulations of simple models of athermal, bidisperse, soft-core, massive disks in two dimensions, as a function of packing fraction ϕ , inelasticity of collisions as measured by a parameter Q , and applied uniform shear strain rate γ ˙. Our particles have contact interactions consisting of normally directed elastic repulsion and viscous dissipation, as well as tangentially directed viscous dissipation, but no interparticle Coulombic friction. Mapping the phase diagram in the (ϕ ,Q ) plane for small γ ˙, we find a sharp first-order rheological phase transition from a region with Bagnoldian rheology to a region with Newtonian rheology, and show that the system is always Newtonian at jamming. We consider the rotational motion of particles and demonstrate the crucial importance that the coupling between rotational and translational degrees of freedom has on the phase structure at small Q (strongly inelastic collisions). At small Q , we show that, upon increasing γ ˙, the sharp Bagnoldian-to-Newtonian transition becomes a coexistence region of finite width in the (ϕ ,γ ˙) plane, with coexisting Bagnoldian and Newtonian shear bands. Crossing this coexistence region by increasing γ ˙ at fixed ϕ , we find that discontinuous shear thickening can result if γ ˙ is varied too rapidly for the system to relax to the shear-banded steady state corresponding to the instantaneous value of γ ˙.

Full spatial-field visualization of gas temperature in an air micro-glow discharge by calibrated Schlieren photography

NASA Astrophysics Data System (ADS)

Xiong, Qing; Xu, Le; Wang, Xia; Xiong, Lin; Huang, Qinghua; Chen, Qiang; Wang, Jingang; Peng, Wenxiong; Li, Jiarui

2018-03-01

Gas temperature is an important basic parameter for both fundamental research and applications of plasmas. In this work, efforts were made to visualize the full spatial field of gas temperature (T g) in a microdischarge with sharp T g gradients by a method of calibrated Schlieren (CS) photography. Compared to other two typical diagnostic approaches, optical emission spectroscopy (OES) and Rayleigh scattering, the proposed CS method exhibits the ability to capture the whole field of gas temperature using a single Schlieren image, even the discharge is of non-luminous zones like Faraday dark space (FDS). The image shows that the T g field in the studied micro-glow air discharge expands quickly with the increase of discharge currents, especially in the cathode region. The two-dimensional maps of gas temperature display a ‘W-shape’ with sharp gradients in both areas of negative and positive glows, slightly arched distributions in the positive column, and cooling zones in the FDS. The obtained T g fields show similar patterns to that of the discharge luminance. With an increase in discharge currents, more electric energy is dissipated by heating air gas and inducing constriction of the low-temperature FDS. Except in the vicinities of electrode boundaries, due to the interference from optical diffraction, the estimated gas temperature distributions are of acceptable accuracy, confirmed by the approaches of OES and UV Rayleigh scattering.

2. X15 RUN UP AREA (Jan 59). A sharp, higher ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. X-15 RUN UP AREA (Jan 59). A sharp, higher altitide low oblique aerial view to the north, showing runway, at far left; X-15 Engine Test Complex in the center. This view predates construction of observation bunkers. - Edwards Air Force Base, X-15 Engine Test Complex, Rogers Dry Lake, east of runway between North Base & South Base, Boron, Kern County, CA

Assessment of using digital manipulation tools for diagnosing mandibular radiolucent lesions

PubMed Central

Raitz, R; Assunção Junior, JNR; Fenyo-Pereira, M; Correa, L; de Lima, LP

2012-01-01

Objective The purpose of this study was to analyse the use of digital tools for image enhancement of mandibular radiolucent lesions and the effects of this manipulation on the percentage of correct radiographic diagnoses. Methods 24 panoramic radiographs exhibiting radiolucent lesions were selected, digitized and evaluated by non-experts (undergraduate and newly graduated practitioners) and by professional experts in oral diagnosis. The percentages of correct and incorrect diagnoses, according to the use of brightness/contrast, sharpness, inversion, highlight and zoom tools, were compared. All dental professionals made their evaluations without (T1) and with (T2) a list of radiographic diagnostic parameters. Results Digital tools were used with low frequency mainly in T2. The most preferred tool was sharpness (45.2%). In the expert group, the percentage of correct diagnoses did not change when any of the digital tools were used. For the non-expert group, there was an increase in the frequency of correct diagnoses when brightness/contrast was used in T2 (p=0.008) and when brightness/contrast and sharpness were not used in T1 (p=0.027). The use or non-use of brightness/contrast, zoom and sharpness showed moderate agreement in the group of experts [kappa agreement coefficient (κ)=0.514, 0.425 and 0.335, respectively]. For the non-expert group there was slight agreement for all the tools used (κ≤0.237). Conclusions Consulting the list of radiographic parameters before image manipulation reduced the frequency of tool use in both groups of examiners. Consulting the radiographic parameters with the use of some digital tools was important for improving correct diagnosis only in the group of non-expert examiners. PMID:22116126

Assessment of using digital manipulation tools for diagnosing mandibular radiolucent lesions.

PubMed

Raitz, R; Assunção Junior, J N R; Fenyo-Pereira, M; Correa, L; de Lima, L P

2012-03-01

The purpose of this study was to analyse the use of digital tools for image enhancement of mandibular radiolucent lesions and the effects of this manipulation on the percentage of correct radiographic diagnoses. 24 panoramic radiographs exhibiting radiolucent lesions were selected, digitized and evaluated by non-experts (undergraduate and newly graduated practitioners) and by professional experts in oral diagnosis. The percentages of correct and incorrect diagnoses, according to the use of brightness/contrast, sharpness, inversion, highlight and zoom tools, were compared. All dental professionals made their evaluations without (T₁) and with (T₂) a list of radiographic diagnostic parameters. Digital tools were used with low frequency mainly in T₂. The most preferred tool was sharpness (45.2%). In the expert group, the percentage of correct diagnoses did not change when any of the digital tools were used. For the non-expert group, there was an increase in the frequency of correct diagnoses when brightness/contrast was used in T₂ (p=0.008) and when brightness/contrast and sharpness were not used in T₁ (p=0.027). The use or non-use of brightness/contrast, zoom and sharpness showed moderate agreement in the group of experts [kappa agreement coefficient (κ) = 0.514, 0.425 and 0.335, respectively]. For the non-expert group there was slight agreement for all the tools used (κ ≤ 0.237). Consulting the list of radiographic parameters before image manipulation reduced the frequency of tool use in both groups of examiners. Consulting the radiographic parameters with the use of some digital tools was important for improving correct diagnosis only in the group of non-expert examiners.

Parametric study on the vortex-induced motions of semi-submersibles: Effect of rounded ratios of the column and pontoon

NASA Astrophysics Data System (ADS)

Liu, Mingyue; Xiao, Longfei; Yang, Jianmin; Tian, Xinliang

2017-05-01

The vortex-induced motions (VIMs) of semi-submersibles have emerged as an important issue in offshore engineering, as they pose a threat to safe and reliable operations and severely affect the fatigue lives of risers and mooring systems. The VIM response depends on the shape of the submerged structure and thus is significantly influenced by the design parameters related to the columns and pontoons. Numerical simulations by the detached Eddy simulation method are validated by experimental data and then used for parametric analysis of the VIM performance of various semi-submersibles with different column rounded ratios (Rc/L ) and pontoon rounded ratios (Rp/Lp ). The results show that the transverse amplitudes of a semi-submersible with circular columns at a 0° current heading are twice as large as those at a 45° current heading. However, the semi-submersible with rounded square columns shows more significant transverse motions at a 45° current heading than at a 0° current heading. Furthermore, at the 45° current heading, the transverse amplitudes of the semi-submersibles show a rapid increase as the column radius increases in the range of Rc/L <0.1 . The peak values remain roughly the same for 0.1 ≤Rc/L ≤0.2 and then decrease as the column radius increases (Rc/L ≥0.3 ). In addition, the effect of the pontoon shape on the transverse response is negligible for semi-submersibles with sharp square columns, while for semi-submersibles with rounded square columns or circular columns, the sharp rectangular pontoons greatly mitigate the VIM response.

Sharps and high-pressure injection injuries in veterinary and animal workers.

PubMed

Robertson, Colin E; Ackerman, Nicola A; Burke, Francis D; Reilly, William J

2016-02-01

Needlestick and 'sharps' injuries among those working with animals are a significant, under-reported and often ill-understood problem. Many patients present initially to Emergency Departments, where their potential to cause local and systemic infections and injury, zoonoses, allergic or anaphylactic reactions and death may be unrecognized. Increased awareness of the possibility of adverse effects and the consequences of these specific injuries is essential.

Observations from ERTS of overgrazing and cultivation impact on the earth's surface

NASA Technical Reports Server (NTRS)

Otterman, J.; Walter, L. S.; Schmugge, T. J.

1976-01-01

ERTS-1 imagery was surveyed for cases of anthropogenic impact, similar to that in the Sinai, evidenced by the Sinai/Negev demarcation line. Reflectivities in several such cases were analyzed using ERTS computer compatible tapes. Sharp increases of surface reflectivity show the severe impact of overgrazing found in several places around the world. Agricultural cultivation can also result in pronounced change of reflectivities, as evidenced by the Montana, USA/Canada demarcation line. Such processes have probably been going on since prehistoric times, increasing with the human population and with the population of the grazing herds.

Positive temporal sharp waves in preterm infants with and without brain ultrasound lesions.

PubMed

Castro Conde, José Ramón; Martínez, Eduardo Doménech; Campo, Candelaria González; Pérez, Arturo Méndez; McLean, Michael Lee

2004-11-01

Clinical significance of neonatal positive temporal sharp waves (PTS) is controversial. The aim of this work is to study (1) PTS incidence in preterm infants with or without major ultrasound lesion (MUL) per gestational age (GA), and (2) the relationship between PTS in both sleep states and other electroencephalographic (EEG) findings with poor prognoses. 97 preterm infants of <27-36 weeks GA, and 12 full-term healthy infants were presented. Prospective study included (1) neurodevelopmental assessment at 40-42 weeks conceptional age (CA), (2) serial neurosonography, and (3) EEG recording at postnatal week 1, 2, 4 and at 40-42 weeks CA. In 50 neonates without MUL, peak PTS was at 31-32 weeks GA. In 47 neonates with MUL, PTS increased significantly from week 2 after birth, descending at the 4th. Neonates of <33 weeks GA with MUL showed significantly increased PTS at term. A significant relationship was found between PTS and other EEG abnormalities with poor neurologic prognoses. PTS incidence varied with sleep states, being predominant in indeterminate sleep in neonates with MUL. PTS increased significantly in infants with MUL, mainly at week 2 of postnatal life, persisting high until term CA, and correlated with other abnormal EEG findings. PTS are highly sensitive to MUL.

Sample Skewness as a Statistical Measurement of Neuronal Tuning Sharpness

PubMed Central

Samonds, Jason M.; Potetz, Brian R.; Lee, Tai Sing

2014-01-01

We propose using the statistical measurement of the sample skewness of the distribution of mean firing rates of a tuning curve to quantify sharpness of tuning. For some features, like binocular disparity, tuning curves are best described by relatively complex and sometimes diverse functions, making it difficult to quantify sharpness with a single function and parameter. Skewness provides a robust nonparametric measure of tuning curve sharpness that is invariant with respect to the mean and variance of the tuning curve and is straightforward to apply to a wide range of tuning, including simple orientation tuning curves and complex object tuning curves that often cannot even be described parametrically. Because skewness does not depend on a specific model or function of tuning, it is especially appealing to cases of sharpening where recurrent interactions among neurons produce sharper tuning curves that deviate in a complex manner from the feedforward function of tuning. Since tuning curves for all neurons are not typically well described by a single parametric function, this model independence additionally allows skewness to be applied to all recorded neurons, maximizing the statistical power of a set of data. We also compare skewness with other nonparametric measures of tuning curve sharpness and selectivity. Compared to these other nonparametric measures tested, skewness is best used for capturing the sharpness of multimodal tuning curves defined by narrow peaks (maximum) and broad valleys (minima). Finally, we provide a more formal definition of sharpness using a shape-based information gain measure and derive and show that skewness is correlated with this definition. PMID:24555451

The stratigraphy and evolution of lower Mount Sharp from spectral, morphological, and thermophysical orbital data sets

PubMed Central

Ehlmann, B. L.; Arvidson, R. E.; Edwards, C. S.; Grotzinger, J. P.; Milliken, R. E.; Quinn, D. P.; Rice, M. S.

2016-01-01

Abstract We have developed a refined geologic map and stratigraphy for lower Mount Sharp using coordinated analyses of new spectral, thermophysical, and morphologic orbital data products. The Mount Sharp group consists of seven relatively planar units delineated by differences in texture, mineralogy, and thermophysical properties. These units are (1–3) three spatially adjacent units in the Murray formation which contain a variety of secondary phases and are distinguishable by thermal inertia and albedo differences, (4) a phyllosilicate‐bearing unit, (5) a hematite‐capped ridge unit, (6) a unit associated with material having a strongly sloped spectral signature at visible near‐infrared wavelengths, and (7) a layered sulfate unit. The Siccar Point group consists of the Stimson formation and two additional units that unconformably overlie the Mount Sharp group. All Siccar Point group units are distinguished by higher thermal inertia values and record a period of substantial deposition and exhumation that followed the deposition and exhumation of the Mount Sharp group. Several spatially extensive silica deposits associated with veins and fractures show that late‐stage silica enrichment within lower Mount Sharp was pervasive. At least two laterally extensive hematitic deposits are present at different stratigraphic intervals, and both are geometrically conformable with lower Mount Sharp strata. The occurrence of hematite at multiple stratigraphic horizons suggests redox interfaces were widespread in space and/or in time, and future measurements by the Mars Science Laboratory Curiosity rover will provide further insights into the depositional settings of these and other mineral phases. PMID:27867788

Relationship between sharps disposal containers and Clostridium difficile infections in acute care hospitals.

PubMed

Pogorzelska-Maziarz, Monika

2015-10-01

Sharps disposal containers are ubiquitous in health care facilities; however, there is paucity of data on their potential role in pathogen transmission. This study assessed the relationship between use of single-use versus reusable sharps containers and rates of Clostridium difficile infections in a national sample of hospitals. A 2013 survey of 1,990 hospitals collected data on the use of sharps containers. Responses were linked to the 2012 Medicare Provider Analysis and Review dataset. Bivariate and multivariable negative binomial regression were conducted to examine differences in C difficile rates between hospitals using single-use versus reusable containers. There were 604 hospitals who completed the survey; of these, 539 provided data on use of sharps containers in 2012 (27% response rate). Hospitals had, on average, 289 beds (SD ± 203) and were predominantly non-for-profit (67%) and nonteaching (63%). Most used reusable sharps containers (72%). In bivariate regression, hospitals using single-use containers had significantly lower rates of C difficile versus hospitals using reusable containers (incidence rate ratio [IRR] = 0.846, P = .001). This relationship persisted in multivariable regression (IRR = 0.870, P = .003) after controlling for other hospital characteristics. This is the first study to show a link between use of single-use sharps containers and lower C difficile rates. Future research should investigate the potential for environmental contamination of reusable containers and the role they may play in pathogen transmission. Copyright © 2015 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Analysis of regulatory mechanisms of an insulin-inducible SHARP-2 gene by (S)-Equol.

PubMed

Haneishi, Ayumi; Takagi, Katsuhiro; Asano, Kosuke; Yamamoto, Taichi; Tanaka, Takashi; Nakamura, Soichiro; Noguchi, Tamio; Yamada, Kazuya

2012-09-01

Small compounds that activate the insulin-dependent signaling pathway have potential therapeutic applications in controlling type 2 diabetes mellitus. The rat enhancer of split- and hairy-related protein-2 (SHARP-2) is an insulin-inducible transcription factor that decreases expression of the phosphoenolpyruvate carboxykinase gene, a gluconeogenic enzyme gene. In this study, we screened for soybean isoflavones that can induce the rat SHARP-2 gene expression and analyzed their mechanism(s). Genistein and (S)-Equol, a metabolite of daidzein, induced rat SHARP-2 gene expression in H4IIE rat hepatoma cells. The (S)-Equol induction was mediated by both the phosphoinositide 3-kinase- and protein kinase C (PKC)-pathways. When a dominant negative form of atypical PKC lambda (aPKCλ) was expressed, the induction of SHARP-2 mRNA level by (S)-Equol was inhibited. In addition, Western blot analyses showed that (S)-Equol rapidly activated both aPKCλ and classical PKC alpha. Furthermore, the (S)-Equol induction was inhibited by treatment with a RNA polymerase inhibitor or a protein synthesis inhibitor. Finally, a reporter gene assay revealed that the transcriptional stimulation by (S)-Equol was mediated by nucleotide sequences located between -4687 and -4133 of the rat SHARP-2 gene. Thus, we conclude that (S)-Equol is an useful dietary supplement to control type 2 diabetes mellitus. Copyright © 2012 Elsevier Inc. All rights reserved.

End-point sharpness in thermometric titrimetry.

PubMed

Tyrrell, H J

1967-07-01

It is shown that the sharpness of an end-point in a thermometric titration where the simple reaction A + B right harpoon over left harpoon AB takes place, depends on Kc(A') where K is the equilibrium constant for the reaction, and c(A') is the total concentration of the titrand (A) in the reaction mixture. The end-point is sharp if, (i) the enthalpy change in the reaction is not negligible, and (ii) Kc(A') > 10(3). This shows that it should, for example, be possible to titrate 0.1 M acid, pK(A) = 10, using a thennometric end-point. Some aspects of thermometric titrimetry when Kc(A') < 10(3) are also considered.

Design of multiplier-less sharp transition width non-uniform filter banks using gravitational search algorithm

NASA Astrophysics Data System (ADS)

Bindiya T., S.; Elias, Elizabeth

2015-01-01

In this paper, multiplier-less near-perfect reconstruction tree-structured filter banks are proposed. Filters with sharp transition width are preferred in filter banks in order to reduce the aliasing between adjacent channels. When sharp transition width filters are designed as conventional finite impulse response filters, the order of the filters will become very high leading to increased complexity. The frequency response masking (FRM) method is known to result in linear-phase sharp transition width filters with low complexity. It is found that the proposed design method, which is based on FRM, gives better results compared to the earlier reported results, in terms of the number of multipliers when sharp transition width filter banks are needed. To further reduce the complexity and power consumption, the tree-structured filter bank is made totally multiplier-less by converting the continuous filter bank coefficients to finite precision coefficients in the signed power of two space. This may lead to performance degradation and calls for the use of a suitable optimisation technique. In this paper, gravitational search algorithm is proposed to be used in the design of the multiplier-less tree-structured uniform as well as non-uniform filter banks. This design method results in uniform and non-uniform filter banks which are simple, alias-free, linear phase and multiplier-less and have sharp transition width.

A numerically optimized active shield for improved transcranial magnetic stimulation targeting.

PubMed

Hernandez-Garcia, Luis; Hall, Timothy; Gomez, Luis; Michielssen, Eric

2010-10-01

Transcranial magnetic stimulation (TMS) devices suffer of poor targeting and penetration depth. A new approach to designing TMS coils is introduced in order to improve the focus of the stimulation region through the use of actively shielded probes. Iterative optimization techniques were used to design different active shielding coils for TMS probes. The new approach aims to increase the amount of energy deposited in a thin cylindrical region below the probe relative to the energy deposited elsewhere in the region ("sharpness"), whereas, simultaneously increase the induced electric field deep in the target region relative to the surface ("penetration"). After convergence, the resulting designs showed that there is a clear tradeoff between sharpness and penetration that can be controlled by the choice of a tuning parameter. The resulting designs were tested on a realistic human head conductivity model, taking the contribution from surface charges into account. The design of choice reduced penetration depths by 16.7%. The activated surface area was reduced by 24.1% and the volume of the activation was reduced from 42.6% by the shield. Restoring the lost penetration could be achieved by increasing the total power to the coil by 16.3%, but in that case, the stimulated volume reduction was only 13.1% and there was a slight increase in the stimulated surface area (2.9%). Copyright © 2010 Elsevier Inc. All rights reserved.

Genetically engineered hairy root cultures of Hyoscyamus senecionis and H. muticus: ploidy as a promising parameter in the metabolic engineering of tropane alkaloids.

PubMed

Dehghan, Esmaeil; Reed, Darwin W; Covello, Patrick S; Hasanpour, Zeinab; Palazon, Javier; Oksman-Caldentey, Kirsi-Marja; Ahmadi, Farajollah Shahriari

2017-10-01

Tetraploidy improves overexpression of h6h and scopolamine production of H. muticus, while in H. senecionis, pmt overexpression and elicitation can be used as effective methods for increasing tropane alkaloids. The effects of metabolic engineering in a polyploid context were studied by overexpression of h6h in the tetraploid hairy root cultures of H. muticus. Flow cytometry analysis indicated genetic stability in the majority of the clones, while only a few clones showed genetic instability. Among all the diploid and tetraploid clones, the highest level of h6h transgene expression and scopolamine accumulation was interestingly observed in the tetraploid clones of H. muticus. Therefore, metabolic engineering of the tropane biosynthetic pathway in polyploids is suggested as a potential system for increasing the production of tropane alkaloids. Transgenic hairy root cultures of Hyoscyamus senecionis were also established. While overexpression of pmt in H. senecionis was correlated with a sharp increase in hyoscyamine production, the h6h-overexpressing clones were not able to accumulate higher levels of scopolamine than the leaves of intact plants. Applying methyl jasmonate was followed by a sharp increase in the expression of pmt and a drop in the expression of tropinone reductase II (trII) which consequently resulted in the higher biosynthesis of hyoscyamine and total alkaloids in H. senecionis.

Intensively exploited Mediterranean aquifers: resilience to seawater intrusion and proximity to critical thresholds

NASA Astrophysics Data System (ADS)

Mazi, K.; Koussis, A. D.; Destouni, G.

2014-05-01

We investigate seawater intrusion in three prominent Mediterranean aquifers that are subject to intensive exploitation and modified hydrologic regimes by human activities: the Nile Delta, Israel Coastal and Cyprus Akrotiri aquifers. Using a generalized analytical sharp interface model, we review the salinization history and current status of these aquifers, and quantify their resilience/vulnerability to current and future seawater intrusion forcings. We identify two different critical limits of seawater intrusion under groundwater exploitation and/or climatic stress: a limit of well intrusion, at which intruded seawater reaches key locations of groundwater pumping, and a tipping point of complete seawater intrusion up to the prevailing groundwater divide of a coastal aquifer. Either limit can be reached, and ultimately crossed, under intensive aquifer exploitation and/or climate-driven change. We show that seawater intrusion vulnerability for different aquifer cases can be directly compared in terms of normalized intrusion performance curves. The site-specific assessments show that (a) the intruding seawater currently seriously threatens the Nile Delta aquifer, (b) in the Israel Coastal aquifer the sharp interface toe approaches the well location and (c) the Cyprus Akrotiri aquifer is currently somewhat less threatened by increased seawater intrusion.

Solution-processed phase-change VO(2) metamaterials from colloidal vanadium oxide (VO(x)) nanocrystals.

PubMed

Paik, Taejong; Hong, Sung-Hoon; Gaulding, E Ashley; Caglayan, Humeyra; Gordon, Thomas R; Engheta, Nader; Kagan, Cherie R; Murray, Christopher B

2014-01-28

We demonstrate thermally switchable VO2 metamaterials fabricated using solution-processable colloidal nanocrystals (NCs). Vanadium oxide (VOx) NCs are synthesized through a nonhydrolytic reaction and deposited from stable colloidal dispersions to form NC thin films. Rapid thermal annealing transforms the VOx NC thin films into monoclinic, nanocrystalline VO2 thin films that show a sharp, reversible metal-insulator phase transition. Introduction of precise concentrations of tungsten dopings into the colloidal VOx NCs enables the still sharp phase transition of the VO2 thin films to be tuned to lower temperatures as the doping level increases. We fabricate "smart", differentially doped, multilayered VO2 films to program the phase and therefore the metal-insulator behavior of constituent vertically structured layers with temperature. With increasing temperature, we tailored the optical response of multilayered films in the near-IR and IR regions from that of a strong light absorber, in a metal-insulator structure, to that of a Drude-like reflector, characteristic of a pure metallic structure. We demonstrate that nanocrystal-based nanoimprinting can be employed to pattern multilayered subwavelength nanostructures, such as three-dimensional VO2 nanopillar arrays, that exhibit plasmonic dipolar responses tunable with a temperature change.

Investigating model deficiencies in the global budget of ethane

NASA Astrophysics Data System (ADS)

Tzompa Sosa, Z. A.; Keller, C. A.; Turner, A. J.; Mahieu, E.; Franco, B.; Fischer, E. V.

2015-12-01

Many locations in the Northern Hemisphere show a statistically-significant sharp increase in measurements of ethane (C2H6) since 2009. It is hypothesized that the recent massive growth of shale gas exploitation in North America could be the source of this change. However, state-of-the-science chemical transport models are currently unable to reproduce the hemispheric burden of C2H6 or the recent sharp increase, pointing to a potential problem with current emission inventories. To resolve this, we used space-borne CH4 observations from the Greenhouse Gases Observing SATellite (GOSAT) to derive C2H6 emissions. By using known emission ratios to CH4, we estimated emissions of C2H6 from oil and gas activities, biofuels, and biomass burning over North America. The GEOS-Chem global chemical transport model was used to simulate atmospheric abundances of C2H6 with the new emissions estimates. The model is able to reproduce Northern Hemisphere surface concentrations. However, the model significantly under-predicts the amount of C2H6 throughout the column and the observed Northern Hemispheric gradient as diagnosed by comparisons to aircraft observations from the Hiaper Pole-to-Pole (HIPPO) Campaign.

Effect of sharp maximum in ion diffusivity for liquid xenon

NASA Astrophysics Data System (ADS)

Lankin, A. V.; Orekhov, M. A.

2016-11-01

Ion diffusion in a liquid usually could be treated as a movement of an ion cluster in a viscous media. For small ions this leads to a special feature: diffusion coefficient is either independent of the ion size or increases with it. We find a different behavior for small ions in liquid xenon. Calculation of the dependence of an ion diffusion coefficient in liquid xenon on the ion size is carried out. Classical molecular dynamics method is applied. Calculated dependence of the ion diffusion coefficient on its radius has sharp maximums at the ion radiuses 1.75 and 2 Å. Every maximum is placed between two regions with different stable ion cluster configurations. This leads to the instability of these configurations in a small region between them. Consequently ion with radius near 1.75 or 2 Å could jump from one configuration to another. This increases the speed of the diffusion. A simple qualitative model for this effect is suggested. The decomposition of the ion movement into continuous and jump diffusion shows that continuous part of the diffusion is the same as for the ion cluster in the stable region.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giggleman, M.A.; Fitzpatrick, L.C.; Goven, A.J.

Earthworms, Lumbricus terrestris, exposed for 96 h to filter paper saturated with five nominal concentrations of pentachlorophenol, exhibited a 50% lethal concentration (LC50) of 25.0 {micro}g PCP/cm{sup 2} and corresponding whole worm body burden-based 50% lethal dose (LD50) of 877.7 {micro}g PCP/g dry mass. Linear regression modeling showed that worms increased body concentrations (BC = {micro}g PCP/g dry tissue mass) with increasing exposure concentrations (EC) according to BC = 113.5 + 29.5EC. Phagocytosis of yeast cells by immunoactive coelomocytes was suppressed only at body concentrations (863.3 {micro}g PCP/g dry mass) that approximated the calculated LD50 and overlapped those demonstrating lethality,more » indicating a sharp transition between sublethal and lethal toxicity. An exposure concentration of 15 {micro}g PCP/cm{sup 2} produced significant suppression of phagocytosis of yeast cells by immunoactive coelomocytes. However, the average measured body burden from this group approximated the estimated LD50, indicating a sharp toxic response slope. Exposure to 10 {micro}g PCP/cm{sup 2} with a corresponding body concentration of 501.3 {micro}g PCP/g dry mass did not affect phagocytosis. The importance of body burden data is emphasized.« less

Optogenetic activation of septal cholinergic neurons suppresses sharp wave ripples and enhances theta oscillations in the hippocampus.

PubMed

Vandecasteele, Marie; Varga, Viktor; Berényi, Antal; Papp, Edit; Barthó, Péter; Venance, Laurent; Freund, Tamás F; Buzsáki, György

2014-09-16

Theta oscillations in the limbic system depend on the integrity of the medial septum. The different populations of medial septal neurons (cholinergic and GABAergic) are assumed to affect different aspects of theta oscillations. Using optogenetic stimulation of cholinergic neurons in ChAT-Cre mice, we investigated their effects on hippocampal local field potentials in both anesthetized and behaving mice. Cholinergic stimulation completely blocked sharp wave ripples and strongly suppressed the power of both slow oscillations (0.5-2 Hz in anesthetized, 0.5-4 Hz in behaving animals) and supratheta (6-10 Hz in anesthetized, 10-25 Hz in behaving animals) bands. The same stimulation robustly increased both the power and coherence of theta oscillations (2-6 Hz) in urethane-anesthetized mice. In behaving mice, cholinergic stimulation was less effective in the theta (4-10 Hz) band yet it also increased the ratio of theta/slow oscillation and theta coherence. The effects on gamma oscillations largely mirrored those of theta. These findings show that medial septal cholinergic activation can both enhance theta rhythm and suppress peri-theta frequency bands, allowing theta oscillations to dominate.

Sharp wave ripples during learning stabilize hippocampal spatial map

PubMed Central

Roux, Lisa; Hu, Bo; Eichler, Ronny; Stark, Eran; Buzsáki, György

2017-01-01

Cognitive representation of the environment requires a stable hippocampal map but the mechanisms maintaining map representation are unknown. Because sharp wave-ripples (SPW-R) orchestrate both retrospective and prospective spatial information, we hypothesized that disrupting neuronal activity during SPW-Rs affects spatial representation. Mice learned daily a new set of three goal locations on a multi-well maze. We used closed-loop SPW-R detection at goal locations to trigger optogenetic silencing of a subset of CA1 pyramidal neurons. Control place cells (non-silenced or silenced outside SPW-Rs) largely maintained the location of their place fields after learning and showed increased spatial information content. In contrast, the place fields of SPW-R-silenced place cells remapped, and their spatial information remained unaltered. SPW-R silencing did not impact the firing rates or the proportions of place cells. These results suggest that interference with SPW-R-associated activity during learning prevents the stabilization and refinement of the hippocampal map. PMID:28394323

A Compact Multiple Notched Ultra-Wide Band Antenna with an Analysis of the CSRR-TO-CSRR Coupling for Portable UWB Applications.

PubMed

Rahman, MuhibUr; Ko, Dong-Sik; Park, Jung-Dong

2017-09-25

We present a compact ultra-wideband (UWB) antenna integrated with sharp notches with a detailed analysis of the mutual coupling of the multiple notch resonators. By utilizing complementary split ring resonators (CSRR) on the radiating semi-circular patch, we achieve the sharp notch-filtering of various bands within the UWB band without increasing the antenna size. The notched frequency bands include WiMAX, INSAT, and lower and upper WLAN. In order to estimate the frequency shifts of the notch due to the coupling of the nearby CSRRs, an analysis of the coupling among the multiple notch resonators is carried out and we construct the lumped-circuit equivalent model. The time domain analysis of the proposed antenna is performed to show its validity on the UWB application. The measured frequency response of the input port corresponds quite well with the calculations and simulations. The radiation pattern of the implemented quad-notched UWB antenna is nearly omnidirectional in the passband.

A Compact Multiple Notched Ultra-Wide Band Antenna with an Analysis of the CSRR-TO-CSRR Coupling for Portable UWB Applications

PubMed Central

Ko, Dong-Sik

2017-01-01

We present a compact ultra-wideband (UWB) antenna integrated with sharp notches with a detailed analysis of the mutual coupling of the multiple notch resonators. By utilizing complementary split ring resonators (CSRR) on the radiating semi-circular patch, we achieve the sharp notch-filtering of various bands within the UWB band without increasing the antenna size. The notched frequency bands include WiMAX, INSAT, and lower and upper WLAN. In order to estimate the frequency shifts of the notch due to the coupling of the nearby CSRRs, an analysis of the coupling among the multiple notch resonators is carried out and we construct the lumped-circuit equivalent model. The time domain analysis of the proposed antenna is performed to show its validity on the UWB application. The measured frequency response of the input port corresponds quite well with the calculations and simulations. The radiation pattern of the implemented quad-notched UWB antenna is nearly omnidirectional in the passband. PMID:28946658

Atomic and electronic structures of an extremely fragile liquid.

PubMed

Kohara, Shinji; Akola, Jaakko; Patrikeev, Leonid; Ropo, Matti; Ohara, Koji; Itou, Masayoshi; Fujiwara, Akihiko; Yahiro, Jumpei; Okada, Junpei T; Ishikawa, Takehiko; Mizuno, Akitoshi; Masuno, Atsunobu; Watanabe, Yasuhiro; Usuki, Takeshi

2014-12-18

The structure of high-temperature liquids is an important topic for understanding the fragility of liquids. Here we report the structure of a high-temperature non-glass-forming oxide liquid, ZrO2, at an atomistic and electronic level. The Bhatia-Thornton number-number structure factor of ZrO2 does not show a first sharp diffraction peak. The atomic structure comprises ZrO5, ZrO6 and ZrO7 polyhedra with a significant contribution of edge sharing of oxygen in addition to corner sharing. The variety of large oxygen coordination and polyhedral connections with short Zr-O bond lifetimes, induced by the relatively large ionic radius of zirconium, disturbs the evolution of intermediate-range ordering, which leads to a reduced electronic band gap and increased delocalization in the ionic Zr-O bonding. The details of the chemical bonding explain the extremely low viscosity of the liquid and the absence of a first sharp diffraction peak, and indicate that liquid ZrO2 is an extremely fragile liquid.

Atomic and electronic structures of an extremely fragile liquid

PubMed Central

Kohara, Shinji; Akola, Jaakko; Patrikeev, Leonid; Ropo, Matti; Ohara, Koji; Itou, Masayoshi; Fujiwara, Akihiko; Yahiro, Jumpei; Okada, Junpei T.; Ishikawa, Takehiko; Mizuno, Akitoshi; Masuno, Atsunobu; Watanabe, Yasuhiro; Usuki, Takeshi

2014-01-01

The structure of high-temperature liquids is an important topic for understanding the fragility of liquids. Here we report the structure of a high-temperature non-glass-forming oxide liquid, ZrO2, at an atomistic and electronic level. The Bhatia–Thornton number–number structure factor of ZrO2 does not show a first sharp diffraction peak. The atomic structure comprises ZrO5, ZrO6 and ZrO7 polyhedra with a significant contribution of edge sharing of oxygen in addition to corner sharing. The variety of large oxygen coordination and polyhedral connections with short Zr–O bond lifetimes, induced by the relatively large ionic radius of zirconium, disturbs the evolution of intermediate-range ordering, which leads to a reduced electronic band gap and increased delocalization in the ionic Zr–O bonding. The details of the chemical bonding explain the extremely low viscosity of the liquid and the absence of a first sharp diffraction peak, and indicate that liquid ZrO2 is an extremely fragile liquid. PMID:25520236

Electromelting of confined monolayer ice.

PubMed

Qiu, Hu; Guo, Wanlin

2013-05-10

In sharp contrast to the prevailing view that electric fields promote water freezing, here we show by molecular dynamics simulations that monolayer ice confined between two parallel plates can melt into liquid water under a perpendicularly applied electric field. The melting temperature of the monolayer ice decreases with the increasing strength of the external field due to the field-induced disruption of the water-wall interaction induced well-ordered network of the hydrogen bond. This electromelting process should add an important new ingredient to the physics of water.

Sharp increase of radio flux in flaring blazar PKS 1424-41

NASA Astrophysics Data System (ADS)

Nemenashi, Pfesesani; Gaylard, Michael; Ojha, Roopesh

2013-02-01

The Hartebeesthoek Radio Astronomy Observatory (HartRAO) 26m telescope has detected a sharp increase in the flux density of PKS 1424-41 (also known as 2FGL J1428.0-4206, Nolan et al. 2012, ApJS, 199, 31) coinciding with the flaring activity reported at gamma-ray and optical (ATel#4714), X-ray (ATel#4717, ATel#4770) and OIR (ATel#4775) bands. At 8.4 GHz, its flux has risen from 6.1 Jy on 2013 Jan 08 to 7.0 Jy on 2013 Jan 28 and it remains at that level.

The changes in the frequency of daily precipitation in Urmia Lake basin, Iran

NASA Astrophysics Data System (ADS)

Salehi Bavil, Sepideh; Zeinalzadeh, Kamran; Hessari, Behzad

2017-06-01

Urmia Lake, as one of the most valuable saline ecosystems in the world, has faced a sharp drop in the water level in recent years. The trend studies of climatic parameters can be effective in identifying the responsible factors and managing this crisis. This research investigated the frequency trend of daily precipitation in the ranges of less than 5 mm, 5-10 mm, 10-15 mm, 15-20 mm, and more than 20 mm in the Urmia Lake basin. The trend was assessed using Mann-Kendall, Spearman Rho and linear regression tests on 60 stations during a period of 30 years (1981 to 2011). The results showed that in all the three tests, the frequency of daily precipitation of less than 5 mm had a significant increase at 1% level. The 5-10 mm range displayed no significant trend, while the 10-15 mm range showed a significantly decreasing trend. The frequency in the 15-20 mm and above 20 mm ranges showed an insignificant falling trend. The analysis also indicated jumps in 1996 and 1999 (almost coinciding with the sharp drop in the lake's water level). In other words, the frequency trends of daily precipitation with small amounts (as a result, high evapotranspiration loss) were increasing and with large amounts were decreasing. This can be a contributor to reduced run-off and, hence, decreased water entering the lake. The results emphasize the need for changes in the management and consumption of water resources in the basin, in order to adapt to the climatic change.

Enhanced Transmissions Through Three-dimensional Cascade Sharp Waveguide Bends Using C-slit Diaphragms.

PubMed

Yang, Rui; Hu, Bowei; Zhang, Aofang; Gao, Dongxing; Wang, Hui; Shi, Ayuan; Lei, Zhenya; Yang, Pei

2017-03-21

Transmission properties through sharp rectangular waveguide bends are investigated to determine the cut-off bending angles of the wave propagation. We show that a simple metallic diaphragm at the bending corner with properly devised sub-wavelength defect apertures of C-slits would be readily to turn on the transmissions with scarce reflections of the propagating modes, while preserving the integrity of the transmitting fields soon after the bends. In particularly, our design also demonstrates the capability of eliminating all the unwanted cavity resonant transmissions that exist in the three-dimensional cascade sharp waveguide bends, and solely let the desired signals travel along the whole passage of the waveguide. The present approach, using C-slit diaphragms to support the sharp bending behaviors of the guided waves with greatly enhanced transmissions, would be especially effective in constructing novel waveguides and pave the way for the development of more compact and miniaturized electromagnetic systems that exploit these waveguide bends.

Ultra-high spatial resolution multi-energy CT using photon counting detector technology

NASA Astrophysics Data System (ADS)

Leng, S.; Gutjahr, R.; Ferrero, A.; Kappler, S.; Henning, A.; Halaweish, A.; Zhou, W.; Montoya, J.; McCollough, C.

2017-03-01

Two ultra-high-resolution (UHR) imaging modes, each with two energy thresholds, were implemented on a research, whole-body photon-counting-detector (PCD) CT scanner, referred to as sharp and UHR, respectively. The UHR mode has a pixel size of 0.25 mm at iso-center for both energy thresholds, with a collimation of 32 × 0.25 mm. The sharp mode has a 0.25 mm pixel for the low-energy threshold and 0.5 mm for the high-energy threshold, with a collimation of 48 × 0.25 mm. Kidney stones with mixed mineral composition and lung nodules with different shapes were scanned using both modes, and with the standard imaging mode, referred to as macro mode (0.5 mm pixel and 32 × 0.5 mm collimation). Evaluation and comparison of the three modes focused on the ability to accurately delineate anatomic structures using the high-spatial resolution capability and the ability to quantify stone composition using the multi-energy capability. The low-energy threshold images of the sharp and UHR modes showed better shape and texture information due to the achieved higher spatial resolution, although noise was also higher. No noticeable benefit was shown in multi-energy analysis using UHR compared to standard resolution (macro mode) when standard doses were used. This was due to excessive noise in the higher resolution images. However, UHR scans at higher dose showed improvement in multi-energy analysis over macro mode with regular dose. To fully take advantage of the higher spatial resolution in multi-energy analysis, either increased radiation dose, or application of noise reduction techniques, is needed.

Time-Resolved Photoluminescence Studies of Si-doped AlGaN alloys

NASA Astrophysics Data System (ADS)

Nam, K. B.; Li, J.; Nakarmi, M. L.; Lin, J. Y.; Jiang, H. X.

2002-03-01

Si-doped n-type Al x Ga_1-x N alloys with x between 0.3 and 0.5 were grown by metal-organic chemical vapor deposition (MOCVD) on sapphire substrates. Time-resolved photoluminescence (PL) emission spectroscopy and variable temperature Hall-effect measurements were employed to study the optical and electrical properties of these epilayers. Our electrical data revealed that the conductivity of Si-doped Al x Ga_1-x N alloys (x > 0.4) increases with an increase of the Si doping concentration (N_Si) for a fixed x value and exhibits a sharp increase around N_Si= 1x10 ^18cm-3, suggesting the existence of a critical Si doping concentration needed to convert insulating Al x Ga_1-x N alloys (x > 0.4) to n-type conductivity. Time-resolved PL studies also showed that PL decay lifetime and activation energy decrease sharply when Si-doping concentration increases from N_Si= 0 to 1x10 ^18cm-3and then followed by gradual decreases as N_Si further increases. Our results thus suggest that Si-doping reduces the effect of carrier localization in Al x Ga_1-x N alloys and a sharp drop in carrier localization energy occurs at N_Si= 1x10 ^18cm-3, which is the critical Si-doping concentration needed to fill up the localized states in Al x Ga_1-x N alloys (x > 0.4). The implications of these results to UV optoelectronic devices are also discussed.

A new smooth-k space filter approach to calculate halo abundances

NASA Astrophysics Data System (ADS)

Leo, Matteo; Baugh, Carlton M.; Li, Baojiu; Pascoli, Silvia

2018-04-01

We propose a new filter, a smooth-k space filter, to use in the Press-Schechter approach to model the dark matter halo mass function which overcomes shortcomings of other filters. We test this against the mass function measured in N-body simulations. We find that the commonly used sharp-k filter fails to reproduce the behaviour of the halo mass function at low masses measured from simulations of models with a sharp truncation in the linear power spectrum. We show that the predictions with our new filter agree with the simulation results over a wider range of halo masses for both damped and undamped power spectra than is the case with the sharp-k and real-space top-hat filters.

Langley Full-scale-tunnel Investigation of Maximum Lift and Stability Characteristics of an Airplane Having Approximately Triangular Plan Form (DM-1 Glider)

NASA Technical Reports Server (NTRS)

Lovell, J Calvin; Wilson, Herbert A JR

1947-01-01

An investigation of the DM-1 Glider, which had approximately triangular plan form, an aspect ratio of 1.8 and a 60 degree sweptback leading edge, has been conducted in the Langley full-scale tunnel. The investigation consisted of the determination of the separate effects of the following modifications made to the glider on its maximum lift and stability characteristics: (a) installation of sharp leading edges over the inboard semispan of the wing, (b) removal of the vertical fin, (c) sealing of the elevon control-balance slots, (d) installation of redesigned thin vertical surfaces, (e) installation of faired sharp leading edges, and (f) installation of canopy. The maximum lift coefficient of the DM-1 glider was increased from 0.61 to 1.01 by the installation of semispan sharp leading edges, and from 1.01 to 1.24 by the removal of the vertical fin and sealing of the elevon control-balance slots. The highest maximum lift coefficient (1.32) was obtained when the faired sharp leading edges and the thin vertical surfaces were attached to the glider. The original DM-1 glider was longitudinally stable. The semispan sharp leading edges shifted the neutral point forward approximately 3 percent of the root chord at moderate lift coefficients, and the glider configuration with these sharp leading edges attached was longitudinally unstable, for the assumed center-of-gravity location, at lift coefficients above 0.73. Sealing the elevon control-balance slots and installing the faired sharp leading edges, the thin vertical surfaces, and the canopy shifted the neutral point forward approximately 8 percent of the root chord.

A Sharp methodology for VLSI layout

NASA Astrophysics Data System (ADS)

Bapat, Shekhar

1993-01-01

The layout problem for VLSI circuits is recognized as a very difficult problem and has been traditionally decomposed into the several seemingly independent sub-problems of placement, global routing, and detailed routing. Although this structure achieves a reduction in programming complexity, it is also typically accompanied by a reduction in solution quality. Most current placement research recognizes that the separation is artificial, and that the placement and routing problems should be solved ideally in tandem. We propose a new interconnection model, Sharp and an associated partitioning algorithm. The Sharp interconnection model uses a partitioning shape that roughly resembles the musical sharp 'number sign' and makes extensive use of pre-computed rectilinear Steiner trees. The model is designed to generate strategic routing information along with the partitioning results. Additionally, the Sharp model also generates estimates of the routing congestion. We also propose the Sharp layout heuristic that solves the layout problem in its entirety. The Sharp layout heuristic makes extensive use of the Sharp partitioning model. The use of precomputed Steiner tree forms enables the method to model accurately net characteristics. For example, the Steiner tree forms can model both the length of the net and more importantly its route. In fact, the tree forms are also appropriate for modeling the timing delays of nets. The Sharp heuristic works to minimize both the total layout area by minimizing total net length (thus reducing the total wiring area), and the congestion imbalances in the various channels (thus reducing the unused or wasted channel area). Our heuristic uses circuit element movements amongst the different partitioning blocks and selection of alternate minimal Steiner tree forms to achieve this goal. The objective function for the algorithm can be modified readily to include other important circuit constraints like propagation delays. The layout technique first computes a very high-level approximation of the layout solution (i.e., the positions of the circuit elements and the associated net routes). The approximate solution is alternately refined, objective function. The technique creates well defined sub-problems and offers intermediary steps that can be solved in parallel, as well as a parallel mechanism to merge the sub-problem solutions.

Splitting hairs: differentiating between entomological activity, taphonomy, and sharp force trauma on hair.

PubMed

Mazzarelli, Debora; Vanin, Stefano; Gibelli, Daniele; Maistrello, Lara; Porta, Davide; Rizzi, Agostino; Cattaneo, Cristina

2015-03-01

The analysis of hair can provide useful information for the correct evaluation of forensic cases, but studies of trauma on hair are extremely rare. Hair may present lesions caused by traumatic events or by animals: in fact, signs of sharp force weapons on hair may provide important information for the reconstruction of the manner of death, and, for example, may suggest fetishist practice. This study stemmed from a judicial case where it was fundamental to distinguish between sharp force lesions and insect activity on hair. In order to highlight differences between sharp force lesions and insect feeding activity, different experiments were performed with high power microscopy: hair samples were subjected to several lesions by blunt and sharp force trauma; then samples were used as pabulum for two taxa of insects: the common clothes moth (Tineola bisselliella Lepidoptera, Tineidae) and the carpet beetle (Anthrenus sp., Coleoptera, Dermestidae). Hairs were examined from a macroscopic and microscopic point of view by stereomicroscopy and scanning electron microscopy (SEM): the morphological characteristics of the lesions obtained from the different experimental samples were compared. Results show that sharp force trauma produces lesions with regular edges, whereas insects leave concave lesions caused by their "gnawing" activity. These two types of lesions are easily distinguishable from breaking and tearing using SEM. This study demonstrates that insect activity leaves very specific indications on hair and sheds some light on different hair lesions that may be found in forensic cases.

Corrosion Behavior of Ultra-fine Grained 1050 Aluminum Alloy Fabricated by ARB Process in a Buffer Borate Solution

NASA Astrophysics Data System (ADS)

Fattah-alhosseini, A.; Gashti, S. O.

2015-09-01

Accumulative roll bonding (ARB) has been used as a severe plastic deformation process for the industrial production of ultra-fine grained (UFG) and nano-crystalline sheets with excellent mechanical properties. In the present study, the effect of the ARB process on the corrosion behavior of UFG and nano-crystalline 1050 aluminum alloy in a buffer borate solution (pH 5.5) has been investigated. The result of microhardness tests revealed that microhardness values increase with an increasing number of ARB cycles. A sharp increase in microhardness is seen after three ARB cycles, whereas moderate additional increases are observed afterward for up to nine cycles. Also, the XRD results showed that the mean crystallite size decreased to about 91 nm after nine cycles. The potentiodynamic plots show that as a result of ARB, the corrosion behavior of the UFG and nano-crystalline specimens improves, compared to the annealed 1050 aluminum alloy. Moreover, electrochemical impedance spectroscopy measurements showed that the polarization resistance increases with an increasing number of ARB cycles.

Targeted disruption of BMP signaling through type IA receptor (BMPR1A) in osteocyte suppresses SOST and RANKL, leading to dramatic increase in bone mass, bone mineral density and mechanical strength.

PubMed

Kamiya, Nobuhiro; Shuxian, Lin; Yamaguchi, Ryosuke; Phipps, Matthew; Aruwajoye, Olumide; Adapala, Naga Suresh; Yuan, Hui; Kim, Harry K W; Feng, Jian Q

2016-10-01

Recent studies suggest a critical role of osteocytes in controlling skeletal development and bone remodeling although the molecular mechanism is largely unknown. This study investigated BMP signaling in osteocytes by disrupting Bmpr1a under the Dmp1-promoter. The conditional knockout (cKO) mice displayed a striking osteosclerotic phenotype with increased trabecular bone volume, thickness, number, and mineral density as assessed by X-ray and micro-CT. The bone histomorphometry, H&E, and TRAP staining revealed a dramatic increase in trabecular and cortical bone masses but a sharp reduction in osteoclast number. Moreover, there was an increase in BrdU positive osteocytes (2-5-fold) and osteoid volume (~4-fold) but a decrease in the bone formation rate (~85%) in the cKO bones, indicating a defective mineralization. The SEM analysis revealed poorly formed osteocytes: a sharp increase in cell numbers, a great reduction in cell dendrites, and a remarkable change in the cell distribution pattern. Molecular studies demonstrated a significant decrease in the Sost mRNA levels in bone (>95%), and the SOST protein levels in serum (~85%) and bone matrices. There was a significant increase in the β-catenin (>3-fold) mRNA levels as well as its target genes Tcf1 (>6-fold) and Tcf3 (~2-fold) in the cKO bones. We also showed a significant decrease in the RANKL levels of serum proteins (~65%) and bone mRNA (~57%), and a significant increase in the Opg mRNA levels (>20-fold) together with a significant reduction in the Rankl/Opg ratio (>95%), which are responsible for a sharp reduction in the cKO osteoclasts. The values of mechanical strength were higher in cKO femora (i.e. max force, displacement, and work failure). These results suggest that loss of BMP signaling specifically in osteocytes dramatically increases bone mass presumably through simultaneous inhibition of RANKL and SOST, leading to osteoclast inhibition and Wnt activation together. Finally, a working hypothesis is proposed to explain how BMPR1A controls bone remodeling by inhibiting cell proliferation and stimulating differentiation. It is reported that RANKL and SOST are abundantly expressed by osteocytes. Thus, BMP signaling through BMPR1A plays important roles in osteocytes. Copyright © 2016 Elsevier Inc. All rights reserved.

Understanding sharps injuries in home healthcare: The Safe Home Care qualitative methods study to identify pathways for injury prevention.

PubMed

Markkanen, Pia; Galligan, Catherine; Laramie, Angela; Fisher, June; Sama, Susan; Quinn, Margaret

2015-04-11

Home healthcare is one of the fastest growing sectors in the United States. Percutaneous injuries from sharp medical devices (sharps) are a source of bloodborne pathogen infections among home healthcare workers and community members. Sharps use and disposal practices in the home are highly variable and there is no comprehensive analysis of the system of sharps procurement, use and disposal in home healthcare. This gap is a barrier to effective public health interventions. The objectives of this study were to i) identify the full range of pathways by which sharps enter and exit the home, stakeholders involved, and barriers for using sharps with injury prevention features; and ii) assess the leverage points for preventive interventions. This study employed qualitative research methods to develop two systems maps of the use of sharps and prevention of sharps injuries in home healthcare. Twenty-six in-depth interview sessions were conducted including home healthcare agency clinicians, public health practitioners, sharps device manufacturers, injury prevention advocates, pharmacists and others. Interview transcripts were audio-recorded and analyzed thematically using NVIVO qualitative research analysis software. Analysis of supporting archival material also was conducted. All findings guided development of the two maps. Sharps enter the home via multiple complex pathways involving home healthcare providers and home users. The providers reported using sharps with injury prevention features. However, home users' sharps seldom had injury prevention features and sharps were commonly re-used for convenience and cost-savings. Improperly discarded sharps present hazards to caregivers, waste handlers, and community members. The most effective intervention potential exists at the beginning of the sharps systems maps where interventions can eliminate or minimize sharps injuries, in particular with needleless treatment methods and sharps with injury prevention features. Manufacturers and insurance providers can improve safety with more affordable and accessible sharps with injury prevention features for home users. Sharps disposal campaigns, free-of-charge disposal containers, and convenient disposal options remain essential. Sharps injuries are preventable through public health actions that promote needleless treatment methods, sharps with injury prevention features, and safe disposal practices. Communication about hazards regarding sharps is needed for all home healthcare stakeholders.

Implications of psychoactive 'bath salts' use during pregnancy.

PubMed

Gray, Bobbe Ann; Holland, Cindra

2014-01-01

Psychoactive bath salts (PABS) comprise a group of highly dangerous designer drugs showing a sharp escalation in reported U.S. exposures from 2010 through 2012, following rapid spread of the drug in Europe. Since a federal ban on the major ingredients in October 2011, numbers have declined. However, evidence from the United Kingdom shows an initial decline after the UK ban in 2010 with a 400 percent increase in reports by 2012. Actual information about the effect of PABS use on pregnant women and fetuses is almost nonexistent. Clinicians should be aware of the potential maternal, fetal and neonatal effects of PABS. © 2014 AWHONN.

Influence of free-stream disturbances on boundary-layer transition

NASA Technical Reports Server (NTRS)

Harvey, W. D.

1978-01-01

Considerable experimental evidence exists which shows that free stream disturbances (the ratio of root-mean-square pressure fluctuations to mean values) in conventional wind tunnels increase with increasing Mach number at low supersonic to moderate hypersonic speeds. In addition to local conditions, the free stream disturbance level influences transition behavior on simple test models. Based on this observation, existing noise transition data obtained in the same test facility were correlated for a large number of reference sharp cones and flat plates and are shown to collapse along a single curve. This result is a significant improvement over previous attempts to correlate noise transition data.

The early evolution of eukaryotes - A geological perspective

NASA Technical Reports Server (NTRS)

Knoll, Andrew H.

1992-01-01

This paper examines the goodness of fit between patterns of biological and environmental history implied by molecular phylogenies of eukaryotic organisms and the geological records of early eukaryote evolution. It was found that Precambrian geological records show evidence that episodic increases in biological diversity roughly coincided with episodic environmental changes and by sharp increases in atmospheric oxygen concentrations which significantly changed the earth surface environments. Although the goodness of fit among physical and biological changes is gratifyingly high, the records of these changes do not always coincide in time. The additional information in these fields that is needed for complete integration of geological and phylogenic records is suggested.

[Study on the fine structure of K-feldspar of Qichun granite].

PubMed

Du, Deng-Wen; Hong, Han-Lie; Fan, Kan; Wang, Chao-Wen; Yin, Ke

2013-03-01

Fine structure of K-feldspar from the Qichun granite was investigated using X-ray diffraction (XRD), Fourier infrared absorption spectroscopy (FTIR), and inductively coupled plasma mass spectrometry methods to understand the evolution of the granitic magmatism and its correlation to molybdenite mineralization. The XRD results showed that K-feldspar of the potassic alteration veins has higher ordering index and triclinicity and is namely microcline with triclinic symmetry. K-feldspar of the early cretaceous granite has relatively lower ordering index and has widening [131] peak and is locally triclinic ordering. K-feldspar of the late cretaceous granite has lowest ordering index and sharp [131] peak and is honiogeneously monoclinic. The FTIR results showed that the IR spectra of the Qichun K-feldspar are similar to that of orthoclase reported by Farmer (1974). The 640 cm-1 absorption band increases while the 540 cm-' absorption band decreases with increase in K-feldspar ordering index, also, the 1,010 cm-1 absorption band separates into 1,010 and 1,046 cm-1 absorption bands, with a change in the band shape from widening to sharp outline. The ICP-MS results suggested that K-feldspar of the early cretaceous granite has relatively higher metal elements and rare earth elements, and the granite exhibits better mineralization background, K-feldspar of the potassic alteration veins has markedly lower Sr and Ba, indicating that the alteration fluid originated from the granitic magmatism, and hence, potassic alteration is a good indicator for molybdenite exploration.

Influence of adaptive statistical iterative reconstruction algorithm on image quality in coronary computed tomography angiography.

PubMed

Precht, Helle; Thygesen, Jesper; Gerke, Oke; Egstrup, Kenneth; Waaler, Dag; Lambrechtsen, Jess

2016-12-01

Coronary computed tomography angiography (CCTA) requires high spatial and temporal resolution, increased low contrast resolution for the assessment of coronary artery stenosis, plaque detection, and/or non-coronary pathology. Therefore, new reconstruction algorithms, particularly iterative reconstruction (IR) techniques, have been developed in an attempt to improve image quality with no cost in radiation exposure. To evaluate whether adaptive statistical iterative reconstruction (ASIR) enhances perceived image quality in CCTA compared to filtered back projection (FBP). Thirty patients underwent CCTA due to suspected coronary artery disease. Images were reconstructed using FBP, 30% ASIR, and 60% ASIR. Ninety image sets were evaluated by five observers using the subjective visual grading analysis (VGA) and assessed by proportional odds modeling. Objective quality assessment (contrast, noise, and the contrast-to-noise ratio [CNR]) was analyzed with linear mixed effects modeling on log-transformed data. The need for ethical approval was waived by the local ethics committee as the study only involved anonymously collected clinical data. VGA showed significant improvements in sharpness by comparing FBP with ASIR, resulting in odds ratios of 1.54 for 30% ASIR and 1.89 for 60% ASIR ( P  = 0.004). The objective measures showed significant differences between FBP and 60% ASIR ( P  < 0.0001) for noise, with an estimated ratio of 0.82, and for CNR, with an estimated ratio of 1.26. ASIR improved the subjective image quality of parameter sharpness and, objectively, reduced noise and increased CNR.

Magnetocaloric Effect in Layered Organic Conductor λ-(BETS)2FeCl4

NASA Astrophysics Data System (ADS)

Sugiura, Shiori; Shimada, Kazuo; Tajima, Naoya; Nishio, Yutaka; Terashima, Taichi; Isono, Takayuki; Kato, Reizo; Zhou, Biao; Uji, Shinya

2018-04-01

Magnetocaloric effect (MCE) and magnetic torque measurements have been carried out in the π-d system λ-(BETS)2FeCl4 [BETS = bis(ethylenedithio)tetraselenafulvalene], which shows an antiferromagnetic insulating (AFI) phase below ˜8.5 K. In the magnetic torque curve, a sharp structure at ˜1.2 T and a step at ˜10 T are observed at low temperatures, which are caused by the spin-flop (SF) transition and the transition from the AFI to paramagnetic metallic (PM) phase, respectively. The MCE, directly related to the magnetic entropy, shows a small sharp peak at the SF transition and a sharp dip at the AFI-PM transition. The overall feature above 3 K is qualitatively interpreted by a simple picture: antiferromagnetic (AF) π spins and paramagnetic 3d spins at the Fe sites. However, a broad dip in the MCE is additionally found at ˜5 T below ˜3 K, which is not explained by the above picture. The results are compared with those of κ-(BETS)2FeBr4, which shows an AF order of the 3d spins at the Fe sites.

Wafer-Scale Aluminum Nanoplasmonic Resonators with Optimized Metal Deposition

DTIC Science & Technology

2016-01-04

As observed by others, the location of these plasmonic resonances is accompanied by a sharp change in phase ( Figure 6 C and F).48 17 Figure...bottom of the structure. The reflectance curves (Figure 4) do not show sharp resonances between 300 and 500 nm, but a broader depression in...Letters 2015, 15, 6946-6951. 3. Taguchi, A.; Saito, Y.; Watanabe , K.; Yijian, S.; Kawata, S. Tailoring plasmon resonances in the deep-ultraviolet by size

Electron spin resonance of particulate soot samples from automobiles to help environmental studies.

PubMed

Yamanaka, C; Matsuda, T; Ikeya, M

2005-02-01

The application of electron spin resonance (ESR) was studied for diesel soot samples and suspended particulate matter (SPM) from automobile engines. Soot samples or diesel exhaust particles (DEP) were recovered at various points: in the exhaust pipe of a diesel engine, at the dust sampler of a highway tunnel (standard DEP), on the soundproofing wall alongside a heavy traffic road, and on the filters of a dust sampler for SPM. The diesel soot samples apparently showed two ESR spectra: one was a broad spectrum at g=2.1 with a line width of ca. 80-120 mT and the other was a sharp signal of a carbon radical at g=2.003 with a line width of 0.4 mT. Annealing experiments with a DEP sample at 250 degrees C revealed drastic enhancement of the sharp ESR signal, which suggested a thermal process of carbonization of remnant organics. An oximetric study by ESR showed an enhancement of the broad signal in the diesel soot sample as well as in the sharp ESR signal. Therefore, the main part of the broad ESR signal would be attributed to carbon radicals, which form a different configuration, probably closely interacting aggregates. Enhancement of the sharp ESR signal was not observed in the standard DEP sample under vacuum condition, which suggested less adsorption sites on the surface of DEP samples.

Fast effects of glucocorticoids on memory-related network oscillations in the mouse hippocampus.

PubMed

Weiss, E K; Krupka, N; Bähner, F; Both, M; Draguhn, A

2008-05-01

Transient or lasting increases in glucocorticoids accompany deficits in hippocampus-dependent memory formation. Recent data indicate that the formation and consolidation of declarative and spatial memory are mechanistically related to different patterns of hippocampal network oscillations. These include gamma oscillations during memory acquisition and the faster ripple oscillations (approximately 200 Hz) during subsequent memory consolidation. We therefore analysed the effects of acutely applied glucocorticoids on network activity in mouse hippocampal slices. Evoked field population spikes and paired-pulse responses were largely unaltered by corticosterone or cortisol, respectively, despite a slight increase in maximal population spike amplitude by 10 microm corticosterone. Several characteristics of sharp waves and superimposed ripple oscillations were affected by glucocorticoids, most prominently the frequency of spontaneously occurring sharp waves. At 0.1 microm, corticosterone increased this frequency, whereas maximal (10 microm) concentrations led to a reduction. In addition, gamma oscillations became slightly faster and less regular in the presence of high doses of corticosteroids. The present study describes acute effects of glucocorticoids on sharp wave-ripple complexes and gamma oscillations in mouse hippocampal slices, revealing a potential background for memory deficits in the presence of elevated levels of these hormones.

[Increasing the anode characteristics of sharp-focused Coolidge X-ray tubes by changing from a high to a low vacuum].

PubMed

Kanikovskiĭ, V B

2002-01-01

The anode characteristics of up-to-date sharp-focused Coolidge X-ray tubes are analyzed. The reason for differences in the real anode characteristics from theoretical ones has been found to be a higher tube gas pressure than that accepted. There is evidence that there are new third-class X-tubes--electronic tubes with compensation for negative volumetric charge of electrons with positive gas ions.

Sharp comparison theorems for the Klein-Gordon equation in d dimensions

NASA Astrophysics Data System (ADS)

Hall, Richard L.; Zorin, Petr

2016-06-01

We establish sharp (or ’refined’) comparison theorems for the Klein-Gordon equation. We show that the condition Va ≤ Vb, which leads to Ea ≤ Eb, can be replaced by the weaker assumption Ua ≤ Ub which still implies the spectral ordering Ea ≤ Eb. In the simplest case, for d = 1, Ui(x) =∫0xV i(t)dt, i = a or b and for d > 1, Ui(r) =∫0rV i(t)td-1dt, i = a or b. We also consider sharp comparison theorems in the presence of a scalar potential S (a ‘variable mass’) in addition to the vector term V (the time component of a four-vector). The theorems are illustrated by a variety of explicit detailed examples.

Terahertz absorber based on Fano-like resonance of inverted quadrangular frustum pyramid metal grooves and sensor application

NASA Astrophysics Data System (ADS)

Yu, Yingying; Sun, Bo

2018-07-01

We investigate the multi-resonance coupling of inverted quadrangular frustum pyramid (IQFP) groove metal arrays at terahertz frequencies. The surface plasmon resonance (SPR) and groove resonance are induced, resulting in resonance coupling. The dipole of the groove resonance drives the quadrupole of the SPR and creates a sharp Fano-like resonance. The effects of geometry parameters including the width (at the bottom) and height are analyzed in detail. The results show that with the decrease in the sidewall slope of the groove, the confinement of the groove region on the electromagnetic field decreases, thereby increasing the resonance coupling. The Fano-like resonance is enhanced. The sensitivity and quality factor are discussed. The results show that the Fano-like resonance has high sensitivity and quality factor. With the increase in the sidewall slope of the groove, the sensitivity increases, and the quality factor decreases. The results show that the Fano-like resonance of IQFP groove metal arrays has a significant potential for biological monitoring and sensing.

Lock-in of elastically mounted airfoils at a 90° angle of attack

NASA Astrophysics Data System (ADS)

Ehrmann, R. S.; Loftin, K. M.; Johnson, S.; White, E. B.

2014-01-01

Reducing vortex-induced vibration (VIV) of elastically mounted cylinders has applications to petroleum, nuclear, and civil engineering. One simple method is streamlining the cylinder into an airfoil shape. However, if flow direction changes, an elastic airfoil could experience similar oscillations with even more drag. To better understand a general airfoil's response, three elastically mounted airfoil shapes are tested at a 90° angle of attack in a 3 ft by 4 ft wind tunnel. The shapes are a NACA 0018, a sharp leading- and trailing-edge (sharp-sharp) model, and a round leading- and trailing-edge (round-round) model. Mass-damping ranges from 0.96 to 1.44. For comparison to canonical VIV research, a cylinder is also tested. Since lock-in occurs near Rec=125×103, the models are also tested with a trip strip. The NACA 0018 and sharp-sharp configuration show nearly identical responses. The cylinder and round-round airfoil have responses five to eight times larger. Thus, the existence of a single sharp edge is sufficient to greatly reduce VIV at 90° angle of attack. Whereas the cylinder and round-round maximum response amplitudes are similar, cylinder lock-in occurs over a velocity range three times larger than the round-round. The tripped cylinder and round-round models' response is attenuated by 70% compared to their respective clean configurations. Hysteresis is only observed in the circular cylinder and round-round models. Hotwire data indicates the clean cylinder has a unique vortex pattern compared to the other configurations.

High-order centered difference methods with sharp shock resolution

NASA Technical Reports Server (NTRS)

Gustafsson, Bertil; Olsson, Pelle

1994-01-01

In this paper we consider high-order centered finite difference approximations of hyperbolic conservation laws. We propose different ways of adding artificial viscosity to obtain sharp shock resolution. For the Riemann problem we give simple explicit formulas for obtaining stationary one and two-point shocks. This can be done for any order of accuracy. It is shown that the addition of artificial viscosity is equivalent to ensuring the Lax k-shock condition. We also show numerical experiments that verify the theoretical results.

Recent climate warming drives ecological change in a remote high-Arctic lake.

PubMed

Woelders, Lineke; Lenaerts, Jan T M; Hagemans, Kimberley; Akkerman, Keechy; van Hoof, Thomas B; Hoek, Wim Z

2018-05-01

The high Arctic is the fastest warming region on Earth, evidenced by extreme near-surface temperature increase in non-summer seasons, recent rapid sea ice decline and permafrost melting since the early 1990's. Understanding the impact of climate change on the sensitive Arctic ecosystem to climate change has so far been hampered by the lack of time-constrained, high-resolution records and by implicit climate data analyses. Here, we show evidence of sharp growth in freshwater green algae as well as distinct diatom assemblage changes since ~1995, retrieved from a high-Arctic (80 °N) lake sediment record on Barentsøya (Svalbard). The proxy record approaches an annual to biennial resolution. Combining remote sensing and in-situ climate data, we show that this ecological change is concurrent with, and is likely driven by, the atmospheric warming and a sharp decrease in the length of the sea ice covered period in the region, and throughout the Arctic. Moreover, this research demonstrates the value of palaeoclimate records in pristine environments for supporting and extending instrumental records. Our results reinforce and extend observations from other sites that the high Arctic has already undergone rapid ecological changes in response to on-going climate change, and will continue to do so in the future.

Contributions of substorm injections to SYM-H depressions in the main phase of storms

NASA Astrophysics Data System (ADS)

He, Zhaohai; Dai, Lei; Wang, Chi; Duan, Suping; Zhang, Lingqian; Chen, Tao; Roth, I.

2016-12-01

Substorm injections bring energetic particles to the inner magnetosphere. But the role of the injected population in building up the storm time ring current is not well understood. By surveying Los Alamos National Laboratory geosynchronous data during 34 storm main phases, we show evidence that at least some substorm injections can contribute to substorm-time scale SYM-H/Dst depressions in the main phase of storms. For event studies, we analyze two typical events in which the main-phase SYM-H index exhibited stepwise depressions that are correlated with particle flux enhancement due to injections and with AL index. A statistical study is performed based on 95 storm time injection events. The flux increases of the injected population (50-400 keV) are found proportional to the sharp SYM-H depressions during the injection interval. By identifying dispersionless and dispersive injection signals, we estimate the azimuthal extent of the substorm injection. Statistical results show that the injection regions of these storm time substorms are characterized with an azimuthal extent larger than 06:00 magnetic local time. These results suggest that at least some substorm injections may mimic the large-scale enhanced convection and contribute to sharp decreases of Dst in the storm main phase.

Modeling of Electron Transpiration Cooling for Leading Edges of Hypersonic Vehicles

NASA Astrophysics Data System (ADS)

Hanquist, Kyle Matthew

The development of aeronautics has been largely driven by the passion to fly faster. From the flight of the Wright Flyer that flew 48 km/hr to the recent advances in hypersonic flight, most notably NASA's X-43A that flew at over 3 km/s, the velocity of flight has steadily increased. However, as these hypersonic speeds are reached and increased, contradicting aerothermodynamic design requirements present themselves. For example, a hypersonic cruise vehicle requires sharp leading edges to decrease the drag in order to maximize the range. However, the aerodynamic performance gains obtained by having a sharp leading edge come at the cost of very high, localized heating rates. There is currently no ideal way to manage these heating loads for sustained hypersonic flight, especially as flight velocities continue to increase. An approach that has been recently proposed involves using thermo-electric materials on these sharp leading edges to manage the heating loads. When exposed to high convective heating rates, these materials emit a current of electrons that leads to a cooling effect of the surface of the vehicle called electron transpiration cooling (ETC). This dissertation focuses on developing a modeling approach to investigate this phenomenon. The research includes developing and implementing an approach for ETC into a computational fluid dynamics code for simulation of hypersonic flow that accounts for electron emission from the surface. Models for space-charge-limited emission are also developed and implemented in order to accurately determine the level of emission from the surface. This work involves developing analytic models and assessing them using a direct-kinetic plasma sheath solver. Electric field effects are also implemented in the modeling approach, which accounts for forced diffusion and Joule heating. Finally, the modeling approach is coupled to a material response code in order to model the heat transfer into the material surface. Using this modeling approach, ETC is investigated as a viable technology for a wide range of hypersonic operating conditions. This includes altitudes between 30 and 60 km, freestream velocities between 4 and 8 km/s, and leading edge radii between 1 mm and 10 cm. The results presented in this study show that ETC can reduce the leading edge temperature significantly for certain conditions, most notably from 3120 to 1660 K for Mach 26 flight for a sharp leading edge (1 cm). However, at lower velocities, the cooling effect can be diminished by space-charge limits in the plasma sheath. ETC is shown to be most effective at cooling hotter surfaces (e.g. high freestream velocities and sharp leading edges) and the level of ionization in the flowfield can help the emission overcome space-charge limits. The modeling approach is assessed using experiments from the 1960s where thermionic emission was investigated as a mode of power generation for reentry vehicles. The computational results produce a wide range of emitted current due to the uncertainty in the freestream conditions and material properties, but they still agree well with the experiments. Overall, this work indicates that ETC is a viable method of managing the immense heat loads on sharp leading edges during hypersonic flight for certain conditions and motivates future work in the area both computationally and experimentally.

Increasing spatial resolution and comparison of MR imaging sequences for the inner ear

NASA Astrophysics Data System (ADS)

Snyder, Carl J.; Bolinger, Lizann; Rubinstein, Jay T.; Wang, Ge

2002-04-01

The size and location of the cochlea and cochlear nerve are needed to assess the feasibility of cochlea implantation, provide information for surgical planning, and aid in construction of cochlear models. Models of implant stimulation incorporating anatomical and physiological information are likely to provide a better understanding of the biophysics of information transferred with cochlear implants and aid in electrode design and arrangement on cochlear implants. Until recently MR did not provide the necessary image resolution and suffered from long acquisition times. The purpose of this study was to optimize both Fast Spin Echo (FSE) and Steady State Free Precession (FIESTA) imaging scan parameters for the inner ear and comparatively examine both for improved image quality and increased spatial resolution. Image quality was determined by two primary measurements, signal to noise ratio (SNR), and image sharpness. Optimized parameters for FSE were 120ms, 3000ms, 64, and 32.25kHz for the TE, TR, echo train length, and bandwidth, respectively. FIESTA parameters were optimized to 2.7, 5.5ms, 70 degree(s), and 62.5kHz, for TE, TR, flip angle, and bandwidth, respectively. While both had the same in-plane spatial resolution, 0.625mm, FIESTA data shows higher SNR per acquisition time and better edge sharpness.

An improved moving average technical trading rule

NASA Astrophysics Data System (ADS)

Papailias, Fotis; Thomakos, Dimitrios D.

2015-06-01

This paper proposes a modified version of the widely used price and moving average cross-over trading strategies. The suggested approach (presented in its 'long only' version) is a combination of cross-over 'buy' signals and a dynamic threshold value which acts as a dynamic trailing stop. The trading behaviour and performance from this modified strategy are different from the standard approach with results showing that, on average, the proposed modification increases the cumulative return and the Sharpe ratio of the investor while exhibiting smaller maximum drawdown and smaller drawdown duration than the standard strategy.

Midlatitude D region variations measured from broadband radio atmospherics

NASA Astrophysics Data System (ADS)

Han, Feng

The high power, broadband very low frequency (VLF, 3--30 kHz) and extremely low frequency (ELF, 3--3000 Hz) electromagnetic waves generated by lightning discharges and propagating in the Earth-ionosphere waveguide can be used to measure the average electron density profile of the lower ionosphere (D region) across the wave propagation path due to several reflections by the upper boundary (lower ionosphere) of the waveguide. This capability makes it possible to frequently and even continuously monitor the D region electron density profile variations over geographically large regions, which are measurements that are essentially impossible by other means. These guided waves, usually called atmospherics (or sferics for short), are recorded by our sensors located near Duke University. The purpose of this work is to develop and implement algorithms to derive the variations of D region electron density profile which is modeled by two parameters (one is height and another is sharpness), by comparing the recorded sferic spectra to a series of model simulated sferic spectra from using a finite difference time domain (FDTD) code. In order to understand the time scales, magnitudes and sources for the midlatitude nighttime D region variations, we analyzed the sferic data of July and August 2005, and extracted both the height and sharpness of the D region electron density profile. The heights show large temporal variations of several kilometers on some nights and the relatively stable behavior on others. Statistical calculations indicate that the hourly average heights during the two months range between 82.0 km and 87.2 km with a mean value of 84.9 km and a standard deviation of 1.1 km. We also observed spatial variations of height as large as 2.0 km over 5 degrees latitudes on some nights, and no spatial variation on others. In addition, the measured height variations exhibited close correlations with local lightning occurrence rate on some nights but no correlation with local lightning or displaced lightning on others. The nighttime profile sharpness during 2.5 hours in two different nights was calculated, and the results were compared to the equivalent sharpness derived from International Reference Ionosphere (IRI) models. Both the absolute values and variation trends in IRI models are different from those in broadband measurements. Based on sferic data similar to those for nighttime, we also measured the day-time D region electron density profile variations in July and August 2005 near Duke University. As expected, the solar radiation is the dominant but not the only determinant source for the daytime D region profile height temporal variations. The observed quiet time heights showed close correlations with solar zenith angle changes but unexpected spatial variations not linked to the solar zenith angle were also observed on some days, with 15% of days exhibiting regional differences larger than 0.5 km. During the solar flare, the induced height change was approximately proportional to the logarithm of the X-ray fluxes. During the rising and decaying phases of the solar flare, the height changes correlated more consistently with the short (wavelength 0.5--4 A), rather than the long (wavelength 1--8 A) X-ray flux changes. The daytime profile sharpness during morning, noontime and afternoon periods in three different days and for the solar zenith angle range 20 to 75 degrees was calculated. These broadband measured results were compared to narrowband VLF measurements, IRI models and Faraday rotation base IRI models (called FIRI). The estimated sharpness from all these sources was more consistent when the solar zenith angle was small than when it was large. By applying the nighttime and daytime measurement techniques, we also derived the D region variations during sunrise and sunset periods. The measurements showed that both the electron density profile height and sharpness decrease during the sunrise period while increase during the sunset period.

Sharp conditions for global stability of Lotka-Volterra systems with distributed delays

NASA Astrophysics Data System (ADS)

Faria, Teresa

We give a criterion for the global attractivity of a positive equilibrium of n-dimensional non-autonomous Lotka-Volterra systems with distributed delays. For a class of autonomous Lotka-Volterra systems, we show that such a criterion is sharp, in the sense that it provides necessary and sufficient conditions for the global asymptotic stability independently of the choice of the delay functions. The global attractivity of positive equilibria is established by imposing a diagonal dominance of the instantaneous negative feedback terms, and relies on auxiliary results showing the boundedness of all positive solutions. The paper improves and generalizes known results in the literature, namely by considering systems with distributed delays rather than discrete delays.

Pretreatment with β-adrenergic receptor agonists facilitates induction of LTP and sharp wave ripple complexes in rodent hippocampus.

PubMed

Ul Haq, Rizwan; Anderson, Marlene; Liotta, Agustin; Shafiq, Maria; Sherkheli, Muhammad Azhar; Heinemann, Uwe

2016-12-01

Norepinephrine, is involved in the enhancement of learning and memory formation by regulating synaptic mechanisms through its ability to activate pre- and post-synaptic adrenergic receptors. Here we show that β-agonists of norepinephrine facilitate the induction of both associational LTP and sharp wave ripples (SPW-Rs) in acute slices of rat hippocampus in area CA3. Surprisingly, this facilitating effect persists when slices are only pretreated with β-receptor agonists followed by wash out and application of the unspecific β-adrenoreceptor (βAR) antagonist propranolol. During application of βAR agonists repeated stimulation resulted in facilitated induction of SPW-Rs. Since SPW-Rs are thought to be involved in memory replay we studied the effects of βAR-agonists on spontaneous SPW-Rs in murine hippocampus and found that amplitude and incidence of SPW-Rs increased. These effects involve cyclic-AMP and the activation of protein kinase A and suggest a supportive role in memory consolidation. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Marketing the health care experience: eight steps to infuse brand essence into your organization.

PubMed

Lofgren, Diane Gage; Rhodes, Sonia; Miller, Todd; Solomon, Jared

2006-01-01

One of the most elusive challenges in health care marketing is hitting on a strategy to substantially differentiate your organization in the community and drive profitable business. This article describes how Sharp HealthCare, the largest integrated health care delivery system in San Diego, has proven that focusing first on improving the health care experience for patients, physicians, and employees can provide the impetus for a vital marketing strategy that can lead to increased market share and net revenue. Over the last five years, this nonprofit health system has transformed the health care experience into tangible actions that are making a difference in the lives of all those the system serves. That difference has become Sharp's "brand essence"--a promise to the community that has been made through marketing, public relations, and advertising and then delivered through the dedicated work of Sharp's 14,000 team members. They call this performance improvement strategy The Sharp Experience. This article outlines the eight-step journey that led the organization to this brand essence marketing campaign, a campaign whose centerpiece is an award-winning 30-minute television documentary that use real-time patient stories to demonstrate Sharp's focus on service and patient-centered care against a backdrop of clinical quality and state-of-the-art technology, and documentary-style radio and television commercials.

Unsteady aerodynamic analysis of space shuttle vehicles. Part 2: Steady and unsteady aerodynamics of sharp-edged delta wings

NASA Technical Reports Server (NTRS)

Ericsson, L. E.; Reding, J. P.

1973-01-01

An analysis of the steady and unsteady aerodynamics of sharp-edged slender wings has been performed. The results show that slender wing theory can be modified to give the potential flow static and dynamic characteristics in incompressible flow. A semiempirical approximation is developed for the vortex-induced loads, and it is shown that the analytic approximation for sharp-edged slender wings gives good prediction of experimentally determined steady and unsteady aerodynamics at M = 0 and M = 1. The predictions are good not only for delta wings but also for so-called arrow and diamond wings. The results indicate that the effects of delta planform lifting surfaces can be included in a simple manner when determining elastic launch vehicle dynamic characteristics. For Part 1 see (N73-32763).

Sharp magnetic structures from dynamos with density stratification

NASA Astrophysics Data System (ADS)

Jabbari, Sarah; Brandenburg, Axel; Kleeorin, Nathan; Rogachevskii, Igor

2017-05-01

Recent direct numerical simulations (DNS) of large-scale turbulent dynamos in strongly stratified layers have resulted in surprisingly sharp bipolar structures at the surface. Here, we present new DNS of helically and non-helically forced turbulence with and without rotation and compare with corresponding mean-field simulations (MFS) to show that these structures are a generic outcome of a broader class of dynamos in density-stratified layers. The MFS agree qualitatively with the DNS, but the period of oscillations tends to be longer in the DNS. In both DNS and MFS, the sharp structures are produced by converging flows at the surface and might be driven in non-linear stage of evolution by the Lorentz force associated with the large-scale dynamo-driven magnetic field if the dynamo number is at least 2.5 times supercritical.

Observation of amorphous to crystalline phase transformation in Te substituted Sn-Sb-Se thin films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chander, Ravi, E-mail: rcohri@yahoo.com

2015-05-15

Thin films of Sn-Sb-Se-Te (8 ≤ x ≤ 14) chalcogenide system were prepared by thermal evaporation technique using melt quenched bulk samples. The as-prepared thin films were found amorphous as evidenced from X-ray diffraction studies. Resistivity measurement showed an exponential decrease with temperature upto critical temperature (transition temperature) beyond which a sharp decrease was observed and with further increase in temperature showed an exponential decrease in resistivity with different activation energy. The transition temperature showed a decreasing trend with tellurium content in the sample. The resistivity measurement during cooling run showed no abrupt change in resistivity. The resistivity measurements ofmore » annealed films did not show any abrupt change revealing the structural transformation occurring in the material. The transition width showed an increase with tellurium content in the sample. The resistivity ratio showed two order of magnitude improvements for sample with higher tellurium content. The observed transition temperature in this system was found quite less than already commercialized Ge-Sb-Te system for optical and electronic memories.« less

Assessing the impacts of ethanol and isobutanol on gaseous and particulate emissions from flexible fuel vehicles.

PubMed

Karavalakis, Georgios; Short, Daniel; Russell, Robert L; Jung, Heejung; Johnson, Kent C; Asa-Awuku, Akua; Durbin, Thomas D

2014-12-02

This study investigated the effects of higher ethanol blends and an isobutanol blend on the criteria emissions, fuel economy, gaseous toxic pollutants, and particulate emissions from two flexible-fuel vehicles equipped with spark ignition engines, with one wall-guided direct injection and one port fuel injection configuration. Both vehicles were tested over triplicate Federal Test Procedure (FTP) and Unified Cycles (UC) using a chassis dynamometer. Emissions of nonmethane hydrocarbons (NMHC) and carbon monoxide (CO) showed some statistically significant reductions with higher alcohol fuels, while total hydrocarbons (THC) and nitrogen oxides (NOx) did not show strong fuel effects. Acetaldehyde emissions exhibited sharp increases with higher ethanol blends for both vehicles, whereas butyraldehyde emissions showed higher emissions for the butanol blend relative to the ethanol blends at a statistically significant level. Particulate matter (PM) mass, number, and soot mass emissions showed strong reductions with increasing alcohol content in gasoline. Particulate emissions were found to be clearly influenced by certain fuel parameters including oxygen content, hydrogen content, and aromatics content.

Economic Evaluation of a Problem Solving Intervention to Prevent Recurrent Sickness Absence in Workers with Common Mental Disorders

PubMed Central

Arends, Iris; Bültmann, Ute; van Rhenen, Willem; Groen, Henk; van der Klink, Jac J. L.

2013-01-01

Objectives Workers with common mental disorders (CMDs) frequently experience recurrent sickness absence but scientifically evaluated interventions to prevent recurrences are lacking. The objectives of this study are to evaluate the cost-effectiveness and cost-benefit of a problem solving intervention aimed at preventing recurrent sickness absence in workers with CMDs compared to care as usual. Methods An economic evaluation was conducted alongside a cluster-randomised controlled trial with 12 months follow-up. Treatment providers were randomised to either a 2-day training in the SHARP-at work intervention, i.e. a problem solving intervention, or care as usual. Effect outcomes were the incidence of recurrent sickness absence and time to recurrent sickness absence. Self-reported health care utilisation was measured by questionnaires. A cost-effectiveness analysis (CEA) from the societal perspective and a cost-benefit analysis (CBA) from the employer’s perspective were conducted. Results The CEA showed that the SHARP-at work intervention was more effective but also more expensive than care as usual. The CBA revealed that employer’s occupational health care costs were significantly higher in the intervention group compared to care as usual. Overall, the SHARP-at work intervention showed no economic benefit compared to care as usual. Conclusions As implementation of the SHARP-at work intervention might require additional investments, health care policy makers need to decide if these investments are worthwhile considering the results that can be accomplished in reducing recurrent sickness absence. PMID:23951270

Super-resolved microsphere-assisted Mirau digital holography by oblique illumination

NASA Astrophysics Data System (ADS)

Abbasian, Vahid; Ganjkhani, Yasaman; Akhlaghi, Ehsan A.; Anand, Arun; Javidi, Bahram; Moradi, Ali-Reza

2018-06-01

In this paper, oblique illumination is used to improve the lateral resolution and edge sharpness in microsphere (MS)-assisted Mirau digital holographic microscopy (Mirau-DHM). Abbe showed that tilting the illumination light allows entrance of higher spatial frequencies into the imaging system thus increasing the resolution power. We extended the idea to common-path DHM, based on Mirau objective, toward super-resolved 3D imaging. High magnification Mirau objectives are very expensive and low-magnification ones suffer from low resolution, therefore, any attempt to increase the effective resolution of the system may be of a great interest. We have already demonstrated the effective resolution increasing of a Mirau-DHM system by incorporating a transparent MS within the working distance of the objective. Here, we show that by integrating a MS-assisted Mirau-DHM with the oblique illumination even higher resolutions can be achieved. We have applied the technique for various samples and have shown the increase in the lateral resolution for the both cases of Mirau-DHM with and without the MS.

Multipole plasmons in graphene nanoellipses

NASA Astrophysics Data System (ADS)

Wang, Weihua; Song, Zhengyong

2018-02-01

We study multipole plasmons in graphene nanoellipses under the quasi-static approximation. The graphene is characterized by a homogeneous surface conductivity, and two coupled differential and integral equations are solved self-consistently to investigate the plasmonic modes in nanoellipses with a fixed area. With respect to the major axis, the symmetric and antisymmetric modes originally doubly degenerate in nanodisks will show different behavior as the semi-major axis increases. The eigen frequencies of the symmetric modes decrease, while those of the antisymmetric modes increase. At the edges, the phase changes of the symmetric dipole modes are linear and independent on structural changes; the phase changes of antisymmetric modes deviate from linear relationship, and the deviation depends on the semi-major axis. As a very large aspect ratio, they exhibit sharp peaks at the endpoints of the minor axis and zero phase changes at the endpoints of the major axis. The non-degenerate breathing mode shows its hot spots at the endpoints of the minor axis, and its eigen frequency gradually increases as the semi-major axis increases.

Now or later? Understanding the etiologic period of suicide

PubMed Central

Vandoros, Sotiris; Kavetsos, Georgios

2015-01-01

Previous research shows that the announcement of austerity measures leads to an immediate and short-lived increase in behaviour that demonstrates anxiety, stress, frustration and other mental effects. This paper uses evidence from the same natural experiment to study whether, for a given decision to commit suicide (as documented by the overall increase over the study period), suicides follow immediately after the announcement of austerity measures in Greece; or whether this is an effect that matures in peoples' minds before being transformed into action. We use evidence from a natural experiment and follow an econometric approach. Our findings show that, despite an overall sharp increase in suicides over the study period, the increase does not follow immediately in the first few days after each such negative event. This suggests that suicides are not spontaneous. They are rather decisions that take time to mature. This time lag implies that suicides arguably attributed to recessions are, in principle, preventable and underlines the importance of mental health services. PMID:26844154

Viscous properties of aluminum oxide nanotubes and aluminium oxide nanoparticles - silicone oil suspensions

NASA Astrophysics Data System (ADS)

Thapa, Ram; French, Steven; Delgado, Adrian; Ramos, Carlos; Gutierrez, Jose; Chipara, Mircea; Lozano, Karen

2010-03-01

Electrorheological (ER) fluids consisting of γ-aluminum oxide nanotubes and γ-aluminum oxide nanoparticles dispersed within silicone oil were prepared. The relationship between shear stress and shear rate was measured and theoretically simulated by using an extended Bingham model for both the rheological and electrorheological features of these systems. Shear stress and viscosity showed a sharp increase for the aluminum oxide nanotubes suspensions subjected to applied electric fields whereas aluminum oxide nanoparticles suspensions showed a moderate change. It was found that the transition from liquid to solid state (mediated by the applied electric field) can be described by a power law and that for low applied voltages the relationship is almost linear.

Nineteen Victims of Homicide and Attempted Homicide in Sweden-Their Injuries, Cause of Death, and Offender Relationship.

PubMed

Khoshnood, Ardavan; Väfors Fritz, Marie; Ekelund, Ulf

2017-09-01

Victims of homicide and attempted homicide are not uncommon in Sweden. We therefore aimed to study these victims to understand their injuries, their cause of death, and their relationship to the offender. All cases during five years in a district court in Sweden, where an offender had been convicted for homicide or attempted homicide, were identified and the court documents reviewed. Nineteen victims were identified; 14 males and five females, with an average age of 39.1 years. Although knife/sharp weapon was the most common weapon used, the use of firearm caused more deaths. Our study shows higher rates of firearm use than many other countries. The most common anatomical site to be injured by knife/sharp weapon and firearm was the thorax followed by the head. The most common cause of death was hypovolemia, followed by intracranial injuries. The high rate of firearm use shows that firearms are common modus operandi in Sweden often causing lethal injuries, if the offender intends to kill the victim. Our results support other studies showing that it is foremost injuries to the vessels, intracranial injuries, and injuries to intrathoracic organs, which causes a victim's death when assaulted with knife/sharp weapon or firearm.

Transition Prediction in Hypersonic Boundary Layers Using Receptivity and Freestream Spectra

NASA Technical Reports Server (NTRS)

Balakumar, P.; Chou, Amanda

2016-01-01

Boundary-layer transition in hypersonic flows over a straight cone can be predicted using measured freestream spectra, receptivity, and threshold values for the wall pressure fluctuations at the transition onset points. Simulations are performed for hypersonic boundary-layer flows over a 7-degree half-angle straight cone with varying bluntness at a freestream Mach number of 10. The steady and the unsteady flow fields are obtained by solving the two-dimensional Navier-Stokes equations in axisymmetric coordinates using a 5th-order accurate weighted essentially non-oscillatory (WENO) scheme for space discretization and using a third-order total-variation-diminishing (TVD) Runge-Kutta scheme for time integration. The calculated N-factors at the transition onset location increase gradually with increasing unit Reynolds numbers for flow over a sharp cone and remain almost the same for flow over a blunt cone. The receptivity coefficient increases slightly with increasing unit Reynolds numbers. They are on the order of 4 for a sharp cone and are on the order of 1 for a blunt cone. The location of transition onset predicted from the simulation including the freestream spectrum, receptivity, and the linear and the weakly nonlinear evolutions yields a solution close to the measured onset location for the sharp cone. The simulations over-predict transition onset by about twenty percent for the blunt cone.

Advances and Limitations of Atmospheric Boundary Layer Observations with GPS Occultation over Southeast Pacific Ocean

NASA Technical Reports Server (NTRS)

Xie, F.; Wu, D. L.; Ao, C. O.; Mannucci, A. J.; Kursinski, E. R.

2012-01-01

The typical atmospheric boundary layer (ABL) over the southeast (SE) Pacific Ocean is featured with a strong temperature inversion and a sharp moisture gradient across the ABL top. The strong moisture and temperature gradients result in a sharp refractivity gradient that can be precisely detected by the Global Positioning System (GPS) radio occultation (RO) measurements. In this paper, the Constellation Observing System for Meteorology, Ionosphere & Climate (COSMIC) GPS RO soundings, radiosondes and the high-resolution ECMWF analysis over the SE Pacific are analyzed. COSMIC RO is able to detect a wide range of ABL height variations (1-2 kilometer) as observed from the radiosondes. However, the ECMWF analysis systematically underestimates the ABL heights. The sharp refractivity gradient at the ABL top frequently exceeds the critical refraction (e.g., -157 N-unit per kilometer) and becomes the so-called ducting condition, which results in a systematic RO refractivity bias (or called N-bias) inside the ABL. Simulation study based on radiosonde profiles reveals the magnitudes of the N-biases are vertical resolution dependent. The N-bias is also the primary cause of the systematically smaller refractivity gradient (rarely exceeding -110 N-unit per kilometer) at the ABL top from RO measurement. However, the N-bias seems not affect the ABL height detection. Instead, the very large RO bending angle and the sharp refractivity gradient due to ducting allow reliable detection of the ABL height from GPS RO. The seasonal mean climatology of ABL heights derived from a nine-month composite of COSMIC RO soundings over the SE Pacific reveals significant differences from the ECMWF analysis. Both show an increase of ABL height from the shallow stratocumulus near the coast to a much higher trade wind inversion further off the coast. However, COSMIC RO shows an overall deeper ABL and reveals different locations of the minimum and maximum ABL heights as compared to the ECMWF analysis. At low latitudes, despite the decreasing number of COSMIC RO soundings and the lower percentage of soundings that penetrate into the lowest 500-m above the mean-sea-level, there are small sampling errors in the mean ABL height climatology. The difference of ABL height climatology between COSMIC RO and ECMWF analysis over SE Pacific is significant and requires further studies.

A puzzling migratory detour : Are fueling conditions in Alaska driving the movement of juvenile sharp -tailed sandpipers ?

USGS Publications Warehouse

Lindstrom, A.; Gill, Robert E.; Jamieson, S.E.; McCaffery, B.; Wennerberg, Liv; Wikelski, M.; Klaassen, M.

2011-01-01

Making a detour can be advantageous to a migrating bird if fuel-deposition rates at stopover sites along the detour are considerably higher than at stopover sites along a more direct route. One example of an extensive migratory detour is that of the Sharp-tailed Sandpiper (Calidris acuminata), of which large numbers of juveniles are found during fall migration in western Alaska. These birds take a detour of 1500-3400 km from the most direct route between their natal range in northeastern Siberia and nonbreeding areas in Australia. We studied the autumnal fueling rates and fuel loads of 357 Sharp-tailed Sandpipers captured in western Alaska. In early September the birds increased in mass at a rate of only 0.5% of lean body mass day?1. Later in September, the rate of mass increase was about 6% of lean body mass day?1, among the highest values found among similar-sized shorebirds around the world. Some individuals more than doubled their body mass because of fuel deposition, allowing nonstop flight of between 7100 and 9800 km, presumably including a trans-oceanic flight to the southern hemisphere. Our observations indicated that predator attacks were rare in our study area, adding another potential benefit of the detour. We conclude that the most likely reason for the Alaskan detour is that it allows juvenile Sharp-tailed Sandpipers to put on large fuel stores at exceptionally high rates. Copyright ?? The Cooper Ornithological Society 2011.

Reliability testing of the Larsen and Sharp classifications for rheumatoid arthritis of the elbow.

PubMed

Jew, Nicholas B; Hollins, Anthony M; Mauck, Benjamin M; Smith, Richard A; Azar, Frederick M; Miller, Robert H; Throckmorton, Thomas W

2017-01-01

Two popular systems for classifying rheumatoid arthritis affecting the elbow are the Larsen and Sharp schemes. To our knowledge, no study has investigated the reliability of these 2 systems. We compared the intraobserver and interobserver agreement of the 2 systems to determine whether one is more reliable than the other. The radiographs of 45 patients diagnosed with rheumatoid arthritis affecting the elbow were evaluated. Anteroposterior and lateral radiographs were deidentified and distributed to 6 evaluators (4 fellowship-trained upper extremity surgeons and 2 orthopedic trainees). Each evaluator graded all 45 radiographs according to the Larsen and Sharp scoring methods on 2 occasions, at least 2 weeks apart. Overall intraobserver reliability was 0.93 (95% confidence interval [CI], 0.90-0.95) for the Larsen system and 0.92 (95% CI, 0.86-0.96) for the Sharp classification, both indicating substantial agreement. Overall interobserver reliability was 0.70 (95% CI, 0.60-0.80) for the Larsen classification and 0.68 (95% CI, 0.54-0.81) for the Sharp system, both indicating good agreement. There were no significant differences in the intraobserver or interobserver reliability of the systems overall and no significant differences in reliability between attending surgeons and trainees for either classification system. The Larsen and Sharp systems both show substantial intraobserver reliability and good interobserver agreement for the radiographic classification of rheumatoid arthritis affecting the elbow. Differences in training level did not result in substantial variances in reliability for either system. We conclude that both systems can be reliably used to evaluate rheumatoid arthritis of the elbow by observers of varying training levels. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Different Temperature and Cooling Patterns at the Blunt and Sharp Egg Poles Reflect the Arrangement of Eggs in an Avian Clutch

PubMed Central

Šálek, Miroslav E.; Zárybnická, Markéta

2015-01-01

Incubation is an energetically demanding process during which birds apply heat to their eggs to ensure embryonic development. Parent behaviours such as egg turning and exchanging the outer and central eggs in the nest cup affect the amount of heat lost to the environment from individual eggs. Little is known, however, about whether and how egg surface temperature and cooling rates vary among the different areas of an egg and how the arrangement of eggs within the clutch influences heat loss. We performed laboratory (using Japanese quail eggs) and field (with northern lapwing eggs) experiments using infrared imaging to assess the temperature and cooling patterns of heated eggs and clutches. We found that (i) the sharp poles of individual quail eggs warmed to a higher egg surface temperature than did the blunt poles, resulting in faster cooling at the sharp poles compared to the blunt poles; (ii) both quail and lapwing clutches with the sharp poles oriented towards the clutch centre (arranged clutches) maintained higher temperatures over the central part of the clutch than occurred in those clutches where most of the sharp egg poles were oriented towards the exterior (scattered clutches); and (iii) the arranged clutches of both quail and lapwing showed slower cooling rates at both the inner and outer clutch positions than did the respective parts of scattered clutches. Our results demonstrate that egg surface temperature and cooling rates differ between the sharp and blunt poles of the egg and that the orientation of individual eggs within the nest cup can significantly affect cooling of the clutch as a whole. We suggest that birds can arrange their eggs within the nest cup to optimise thermoregulation of the clutch. PMID:25658846

Different temperature and cooling patterns at the blunt and sharp egg poles reflect the arrangement of eggs in an avian clutch.

PubMed

Šálek, Miroslav E; Zárybnická, Markéta

2015-01-01

Incubation is an energetically demanding process during which birds apply heat to their eggs to ensure embryonic development. Parent behaviours such as egg turning and exchanging the outer and central eggs in the nest cup affect the amount of heat lost to the environment from individual eggs. Little is known, however, about whether and how egg surface temperature and cooling rates vary among the different areas of an egg and how the arrangement of eggs within the clutch influences heat loss. We performed laboratory (using Japanese quail eggs) and field (with northern lapwing eggs) experiments using infrared imaging to assess the temperature and cooling patterns of heated eggs and clutches. We found that (i) the sharp poles of individual quail eggs warmed to a higher egg surface temperature than did the blunt poles, resulting in faster cooling at the sharp poles compared to the blunt poles; (ii) both quail and lapwing clutches with the sharp poles oriented towards the clutch centre (arranged clutches) maintained higher temperatures over the central part of the clutch than occurred in those clutches where most of the sharp egg poles were oriented towards the exterior (scattered clutches); and (iii) the arranged clutches of both quail and lapwing showed slower cooling rates at both the inner and outer clutch positions than did the respective parts of scattered clutches. Our results demonstrate that egg surface temperature and cooling rates differ between the sharp and blunt poles of the egg and that the orientation of individual eggs within the nest cup can significantly affect cooling of the clutch as a whole. We suggest that birds can arrange their eggs within the nest cup to optimise thermoregulation of the clutch.

Personality and cognitive profiles of a general synesthetic trait.

PubMed

Rouw, Romke; Scholte, H Steven

2016-07-29

The recent sharp increase in studies on synesthesia has taught us a lot about this fascinating condition. Still, while we define synesthesia as 'the mixing of senses', the great majority of synesthesia studies focus on only one synesthesia type (in particular grapheme-color synesthesia). In this study, a large group of subjects are tested on the presence or absence of different types of synesthesia. Efforts to recruit a representative sample of the Dutch population, not related to or aware of synesthesia as a research topic, helped counter a selection bias or a self-report bias in our subject group. A sharp increase in synesthesia prevalence was found, at least partially due to including many different types of synesthesia in the synesthesia 'diagnoses'. The five synesthesia types reported in the Novich et al (2011) study were obtained; Colored Sequences, Colored Music, Colored Sensations, Spatial Sequences, Non-Visual Sequelae, as well as an additional synesthesia type, Sequence-Personality. No differences were found between synesthetes and non-synesthetes in education level, handedness, age, and sex. The synesthetes showed increased intelligence as compared with matched non-synesthetes. This was a general effect rather than bound to a specific cognitive domain or to a specific (synesthesia-type to stimulus-material) relationship. The expected effect of increased "Openness" in synesthetes was obtained, as well as two unexpected effects in personality traits (increased "Neuroticism" and decreased "Conscientiousness"). We also found increased "Emotionality" (experiencing emotions) and increased "Fantasizing", but synesthetes did not differ in cognitive appraisal of emotions (identifying/analyzing/verbalizing of emotions). The personality and cognitive characteristics were found related to having synesthesia (in general) rather then to particular synesthesia subtypes. This supports the existence of a general synesthetic 'trait', over the notion of relatively independent 'types' of synesthesia. In further support, exploratory analyses showed that a measurement of synesthetic strength (number of subtypes of synesthesia) correlates with stronger findings (increased "Openness", "Fantasizing", and "Emotionality", and decreased "Conscientiousness"). In conclusion, results are in line with the notion of a general synesthetic 'trait', and this synesthetic trait is associated with particular personality traits and cognitive characteristics. Copyright © 2016. Published by Elsevier Ltd.

Pre-processing, registration and selection of adaptive optics corrected retinal images.

PubMed

Ramaswamy, Gomathy; Devaney, Nicholas

2013-07-01

In this paper, the aim is to demonstrate enhanced processing of sequences of fundus images obtained using a commercial AO flood illumination system. The purpose of the work is to (1) correct for uneven illumination at the retina (2) automatically select the best quality images and (3) precisely register the best images. Adaptive optics corrected retinal images are pre-processed to correct uneven illumination using different methods; subtracting or dividing by the average filtered image, homomorphic filtering and a wavelet based approach. These images are evaluated to measure the image quality using various parameters, including sharpness, variance, power spectrum kurtosis and contrast. We have carried out the registration in two stages; a coarse stage using cross-correlation followed by fine registration using two approaches; parabolic interpolation on the peak of the cross-correlation and maximum-likelihood estimation. The angle of rotation of the images is measured using a combination of peak tracking and Procrustes transformation. We have found that a wavelet approach (Daubechies 4 wavelet at 6th level decomposition) provides good illumination correction with clear improvement in image sharpness and contrast. The assessment of image quality using a 'Designer metric' works well when compared to visual evaluation, although it is highly correlated with other metrics. In image registration, sub-pixel translation measured using parabolic interpolation on the peak of the cross-correlation function and maximum-likelihood estimation are found to give very similar results (RMS difference 0.047 pixels). We have confirmed that correcting rotation of the images provides a significant improvement, especially at the edges of the image. We observed that selecting the better quality frames (e.g. best 75% images) for image registration gives improved resolution, at the expense of poorer signal-to-noise. The sharpness map of the registered and de-rotated images shows increased sharpness over most of the field of view. Adaptive optics assisted images of the cone photoreceptors can be better pre-processed using a wavelet approach. These images can be assessed for image quality using a 'Designer Metric'. Two-stage image registration including correcting for rotation significantly improves the final image contrast and sharpness. © 2013 The Authors Ophthalmic & Physiological Optics © 2013 The College of Optometrists.

Characterization of carbonaceous matter in xenolithic clasts from the Sharps (H3.4) meteorite: Constraints on the origin and thermal processing

NASA Astrophysics Data System (ADS)

Kebukawa, Yoko; Zolensky, Michael E.; Chan, Queenie H. S.; Nagao, Keisuke; Kilcoyne, A. L. David; Bodnar, Robert J.; Farley, Charles; Rahman, Zia; Le, Loan; Cody, George D.

2017-01-01

Primitive xenolithic clasts, often referred to as ;dark clasts;, are well known in many regolith breccias. The Sharps H3.4 ordinary chondrite contains unusually large dark clasts up to ∼1 cm across. Poorly-graphitized carbon (PGC), with Fe, Ni metal and described as ;carbon-rich aggregates;, has been reported in these clasts (Brearley, 1990). We report detailed analyses of carbonaceous matter in several identical Sharps clasts using FTIR, Raman, C-XANES, and TEM that provide insight on the extent of thermal processing and possible origin of such clasts. We also prepared acid residues of the clasts using the HCl/HF method and conducted mass spectrometric analysis of the entrained noble gases. Carbonaceous matter is often used to infer thermal history due to its sensitivity to thermal processes. The FTIR spectra of the acid residue from the Sharps clast suggest that carbonaceous matter in the clast contains less hydrogen and oxygen compared to acid residues from typical type 3.4 ordinary chondrites. The metamorphic temperatures obtained by Raman spectroscopy ranges between ∼380 °C and ∼490 °C. TEM observations indicate that the clasts experienced a peak temperature of 300 °C to 400 °C, based on the carbon d002 layer lattice spacing of C-rich aggregates. These estimates are consistent with an earlier estimate of 330 ± 50 °C, that is also estimated by the d002 layer lattice spacing (Brearley, 1990). It should be noted that the lattice spacing thermometer is based on terrestrial metamorphose rocks, and thus temperature was probably underestimated. Meanwhile, the C-XANES spectra of the C-rich aggregates show high exciton intensities, indicative of graphene structures that developed at around 700-800 °C following an extensive period of time (millions of years), however, the surrounding matrix areas experienced lower temperatures of less than 300-500 °C. Noble gas analysis of the acid residue from the Sharps clasts shows that the residue is almost identical with some material reported in carbonaceous chondrites, i.e., heavily enriched in the Q-gas component as well as HL-gas from presolar diamonds and Ne-E(H) from presolar SiC. These results indicate that the C-rich aggregates in the Sharps clasts formed under relatively high temperature conditions, up to 800 °C, and were subsequently mixed with lower temperature matrix, probably in a different parent body, before they were incorporated into the final Sharps lithology by collision.

Black carbon emission reduction strategies in healthcare industry for effective global climate change management.

PubMed

Raila, Emilia Mmbando; Anderson, David O

2017-04-01

Climate change remains one of the biggest threats to life on earth to date with black carbon (BC) emissions or smoke being the strongest cause after carbon dioxide (CO 2 ). Surprisingly, scientific evidence about black carbon emissions reduction in healthcare settings is sparse. This paper presents new research findings on the reduction of black carbon emissions from an observational study conducted at the UN Peacekeeping Operations (MINUSTAH) in Haiti in 2014. Researchers observed 20 incineration cycles, 30 minutes for each cycle of plastic and cardboard sharps healthcare waste (HCW) containers ranged from 3 to 14.6 kg. The primary aim was to determine if black carbon emissions from healthcare waste incineration can be lowered by mainstreaming the use of cardboard sharps healthcare waste containers instead of plastic sharps healthcare waste containers. Similarly, the study looks into whether burning temperature was associated with the smoke levels for each case or not. Independent samples t-tests demonstrated significantly lower black carbon emissions during the incineration of cardboard sharps containers (6.81 ± 4.79% smoke) than in plastic containers (17.77 ± 8.38% smoke); a statistically significant increase of 10.96% smoke (95% Confidence Interval ( CI) [4.4 to 17.5% smoke], p = 0.003). Correspondingly, lower bottom burner temperatures occurred during the incineration of cardboard sharps containers than in plastic (95% Cl [16 to 126°C], p = 0.014). Finally, we expect the application of the new quantitative evidence to form the basis for policy formulation, mainstream the use of cardboard sharps containers and opt for non-incineration disposal technologies as urgent steps for going green in healthcare waste management.

An Observation of Repeating Events at local asperities during a Laboratory Stick-slip Experiment of a Saw-cut Cylindrical Lucite Sample

NASA Astrophysics Data System (ADS)

Gu, C.; Mighani, S.; Prieto, G. A.; Mok, U.; Evans, J. B.; Hager, B. H.; Toksoz, M. N.

2017-12-01

Repeating earthquakes have been found in subduction zones and interpreted as repeated ruptures of small local asperities. Repeating earthquakes have also been found in oil/gas fields, interpreted as the reactivation of pre-existing faults due to fluid injection/extraction. To mimic the fault rupture of a fault with local asperities, we designed a "stick-slip" experiment using a saw-cut cylindrical Lucite sample, which had sharp localized ridges parallel to the strike of the fault plane. The sample was subjected to conventional triaxial loading with a constant confining pressure of 10 MPa. The axial load was then increased to 6 MPa at a constant rate of 0.12 MPa/sec until the sliding occurred along the fault plane. Ultrasonic acoustic emissions (AEs) were monitored with eight PZT sensors. Two cycles of AEs were detected with the occurrence rate that decreased from the beginning to the end of each cycle, while the relative magnitudes increased. Correlation analysis indicated that these AEs were clustered into two groups - those with frequency content between 200-300kHz and a second group with frequency content between 10-50kHz. The locations of the high-frequency events, with almost identical waveforms, show that these events are from the sharp localized ridges on the saw-cut plane. The locations of the low-frequency events show an approaching process to the high-frequency events for each cycle. In this single experiment, there was a correlation of the proximity of the low-frequency events with the subsequent triggering of large high-frequency repeating events.

Influence of adaptive statistical iterative reconstruction algorithm on image quality in coronary computed tomography angiography

PubMed Central

Thygesen, Jesper; Gerke, Oke; Egstrup, Kenneth; Waaler, Dag; Lambrechtsen, Jess

2016-01-01

Background Coronary computed tomography angiography (CCTA) requires high spatial and temporal resolution, increased low contrast resolution for the assessment of coronary artery stenosis, plaque detection, and/or non-coronary pathology. Therefore, new reconstruction algorithms, particularly iterative reconstruction (IR) techniques, have been developed in an attempt to improve image quality with no cost in radiation exposure. Purpose To evaluate whether adaptive statistical iterative reconstruction (ASIR) enhances perceived image quality in CCTA compared to filtered back projection (FBP). Material and Methods Thirty patients underwent CCTA due to suspected coronary artery disease. Images were reconstructed using FBP, 30% ASIR, and 60% ASIR. Ninety image sets were evaluated by five observers using the subjective visual grading analysis (VGA) and assessed by proportional odds modeling. Objective quality assessment (contrast, noise, and the contrast-to-noise ratio [CNR]) was analyzed with linear mixed effects modeling on log-transformed data. The need for ethical approval was waived by the local ethics committee as the study only involved anonymously collected clinical data. Results VGA showed significant improvements in sharpness by comparing FBP with ASIR, resulting in odds ratios of 1.54 for 30% ASIR and 1.89 for 60% ASIR (P = 0.004). The objective measures showed significant differences between FBP and 60% ASIR (P < 0.0001) for noise, with an estimated ratio of 0.82, and for CNR, with an estimated ratio of 1.26. Conclusion ASIR improved the subjective image quality of parameter sharpness and, objectively, reduced noise and increased CNR. PMID:28405477

[Ultrafine particle number concentration and size distribution of vehicle exhaust ultrafine particles].

PubMed

Lu, Ye-qiang; Chen, Qiu-fang; Sun, Zai; Cai, Zhi-liang; Yang, Wen-jun

2014-09-01

Ultrafine particle (UFP) number concentrations obtained from three different vehicles were measured using fast mobility particle sizer (FMPS) and automobile exhaust gas analyzer. UFP number concentration and size distribution were studied at different idle driving speeds. The results showed that at a low idle speed of 800 rmin-1 , the emission particle number concentration was the lowest and showed a increasing trend with the increase of idle speed. The majority of exhaust particles were in Nuclear mode and Aitken mode. The peak sizes were dominated by 10 nm and 50 nm. Particle number concentration showed a significantly sharp increase during the vehicle acceleration process, and was then kept stable when the speed was stable. In the range of 0. 4 m axial distance from the end of the exhaust pipe, the particle number concentration decayed rapidly after dilution, but it was not obvious in the range of 0. 4-1 m. The number concentration was larger than the background concentration. Concentration of exhaust emissions such as CO, HC and NO showed a reducing trend with the increase of idle speed,which was in contrast to the emission trend of particle number concentration.

Changes in the structure and dynamics of marine assemblages dominated by Bifurcaria bifurcata and Cystoseira species over three decades (1977-2007)

NASA Astrophysics Data System (ADS)

Méndez-Sandín, Miguel; Fernández, Consolación

2016-06-01

Two low intertidal assemblages dominated in 1977 by Bifurcaria bifurcata and Cystoseira baccata-Saccorhiza polyschides in the North coast of Spain show changes in the structure and dynamics after 30 years. A re-survey in 2007 detected phenological changes affecting the annual cycle of dominant canopy species. B. bifurcata has shortened its growth period and undergone a decrease in biomass, while C. baccata lengthened its period of growth and increased its biomass. Also important were the disappearance of Saccorhiza polyschides and the increase of Cystoseira tamariscifolia. These changes affect the rest of the species of the assemblages, with a shift in the main understory species and an increase in crustose coralline algae although the overall biomass of the subcanopy was similar. The species richness shows a sharp increase, at the expense of increasing epiphytes and simpler functional and morphological groups. These biological changes agree with the general trends of increasing sea surface temperature and the relaxation of the summer upwelling affecting the North coast of Spain, but the results were unexpected in the case of Bifurcaria bifurcata.

Preoperative and Postoperative Photographs and Surgical Outcomes of Patients With Kyphosis.

PubMed

Albayrak, Akif; Balioglu, Mehmet Bulent; Misir, Abdulhamit; Kargin, Deniz; Tacal, Mehmet Temel; Atici, Yunus; Kaygusuz, Mehmet Akif

2016-10-01

A retrospective clinical study was performed. The aim of the study was to show patients their pre- and postoperative body photographs, and determine the effect on postoperative patient satisfaction for thoracic and thoracolumbar sharp and round angular kyphosis. Previous studies have reported the normative values of pelvic sagittal parameters and the classification of normal patterns of sagittal curvature, but no study has investigated and compared the clinical photographs of sharp and round kyphosis. In patients who underwent surgery for thoracic and thoracolumbar sharp and round angular kyphosis, whole spine anteroposterior and lateral radiographs, and clinical photographs were obtained preoperatively and at the final follow-up. Pelvic and spinal parameters were measured, and the pre- and postoperative photographs were shown to patients. The Scoliosis Research Society 22r (SRS22r) and Short Form 36 surveys were administered to all patients, and the scores were analyzed. Thirty-eight patients diagnosed with kyphosis (mean age 19.6 yr, mean follow-up duration 26.4 mo) were divided into two groups: sharp (18 patients, mean age 20.1 yr) and round (20 patients, mean age 19.6 yr) kyphosis. There was no difference between values in the sharp and round groups in terms of age, follow-up duration, and Risser score (P > 0.05). In both groups, the subscores for pain, self-image, mental health, and satisfaction, except for the function/activity score, and the total score of the SRS22r survey were, however, significantly different between pre- and postoperative photographs. In addition, there was no significant difference between the two groups in any SRS22r domain and Short Form 36 scores. The surgical treatment of kyphosis was uniformly associated with improved quality of life, regardless of the kyphosis type. Thus, showing patients their pre- and postoperative photographs may enhance patient satisfaction, as measured by SRS22r scores. 4.

Nonmonotonous electron mobility due to structurally induced resonant coupling of subband states in an asymmetric double quantum well

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nayak, R. K.; Das, S.; Panda, A. K.

We show that sharp nonmonotic variation of low temperature electron mobility μ can be achieved in GaAs/Al{sub x}Ga{sub 1-x}As barrier delta-doped double quantum well structure due to quantum mechanical transfer of subband electron wave functions within the wells. We vary the potential profile of the coupled structure as a function of the doping concentration in order to bring the subbands into resonance such that the subband energy levels anticross and the eigen states of the coupled structure equally share both the wells thereby giving rise to a dip in mobility. When the wells are of equal widths, the dip inmore » mobility occurs under symmetric doping of the side barriers. In case of unequal well widths, the resonance can be obtained by suitable asymmetric variation of the doping concentrations. The dip in mobility becomes sharp and also the wavy nature of mobility takes a rectangular shape by increasing the barrier width. We show that the dip in mobility at resonance is governed by the interface roughness scattering through step like changes in the subband mobilities. It is also gratifying to show that the drop in mobility at the onset of occupation of second subband is substantially supressed through the quantum mechanical transfer of subband wave functions between the wells. Our results can be utilized for performance enhancement of coupled quantum well devices.« less

Fast sweeping methods for hyperbolic systems of conservation laws at steady state II

NASA Astrophysics Data System (ADS)

Engquist, Björn; Froese, Brittany D.; Tsai, Yen-Hsi Richard

2015-04-01

The idea of using fast sweeping methods for solving stationary systems of conservation laws has previously been proposed for efficiently computing solutions with sharp shocks. We further develop these methods to allow for a more challenging class of problems including problems with sonic points, shocks originating in the interior of the domain, rarefaction waves, and two-dimensional systems. We show that fast sweeping methods can produce higher-order accuracy. Computational results validate the claims of accuracy, sharp shock curves, and optimal computational efficiency.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenau, Philip

A wide variety of propagating disturbances in physical systems are described by equations whose solutions lack a sharp propagating front. We demonstrate that presence of particular nonlinearities may induce such fronts. To exemplify this idea, we study both dissipative u{sub t}+{partial_derivative}{sub x}f(u)=u{sub xx} and dispersive u{sub t}+{partial_derivative}{sub x}f(u)+u{sub xxx}=0 patterns, and show that a weakly singular convection f(u)=-u{sup {alpha}}+u{sup m}, 0<{alpha}<1

The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs.

PubMed

Arieti, Fabiana; Gabus, Caroline; Tambalo, Margherita; Huet, Tiphaine; Round, Adam; Thore, Stéphane

2014-06-01

The Split Ends (SPEN) protein was originally discovered in Drosophila in the late 1990s. Since then, homologous proteins have been identified in eukaryotic species ranging from plants to humans. Every family member contains three predicted RNA recognition motifs (RRMs) in the N-terminal region of the protein. We have determined the crystal structure of the region of the human SPEN homolog that contains these RRMs-the SMRT/HDAC1 Associated Repressor Protein (SHARP), at 2.0 Å resolution. SHARP is a co-regulator of the nuclear receptors. We demonstrate that two of the three RRMs, namely RRM3 and RRM4, interact via a highly conserved interface. Furthermore, we show that the RRM3-RRM4 block is the main platform mediating the stable association with the H12-H13 substructure found in the steroid receptor RNA activator (SRA), a long, non-coding RNA previously shown to play a crucial role in nuclear receptor transcriptional regulation. We determine that SHARP association with SRA relies on both single- and double-stranded RNA sequences. The crystal structure of the SHARP-RRM fragment, together with the associated RNA-binding studies, extend the repertoire of nucleic acid binding properties of RRM domains suggesting a new hypothesis for a better understanding of SPEN protein functions. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

Notched strength of beryllium powder and ingot sheets.

NASA Technical Reports Server (NTRS)

Moss, R. G.

1972-01-01

The effects of notches in thin beryllium sheets were studied as functions of material variables and notch severity. Double edge notched samples having stress concentration factors of 1.0 to 15.4 were prepared by milling to size, etching, and electrical discharge machining the notches. Strength was not reduced greatly by sharp notches, and duller notches were more deleterious than sharp notches. The trend was for reduced strength for dull notches, increased strength for sharper notches, and reduced strength for very sharp notches. Differences in material purity or source of the sheet had little affect on notch sensitivity. The most important factors appear to be oxide content and directionality of the sheet microstructure; high oxide content and highly directional microstructure tend to give more notch sensitivity than low oxide content, and more bidirectional microstructure. Postulated causes of the change in notched/unnotched strength are given.

Sharps Injuries and Other Blood and Body Fluid Exposures Among Home Health Care Nurses and Aides

PubMed Central

Markkanen, Pia K.; Galligan, Catherine J.; Kriebel, David; Chalupka, Stephanie M.; Kim, Hyun; Gore, Rebecca J.; Sama, Susan R.; Laramie, Angela K.; Davis, Letitia

2009-01-01

Objectives. We quantified risks of sharp medical device (sharps) injuries and other blood and body fluid exposures among home health care nurses and aides, identified risk factors, assessed the use of sharps with safety features, and evaluated underreporting in workplace-based surveillance. Methods. We conducted a questionnaire survey and workplace-based surveillance, collaborating with 9 home health care agencies and 2 labor unions from 2006 to 2007. Results. Approximately 35% of nurses and 6.4% of aides had experienced at least 1 sharps injury during their home health care career; corresponding figures for other blood and body fluid exposures were 15.1% and 6.7%, respectively. Annual sharps injuries incidence rates were 5.1 per 100 full-time equivalent (FTE) nurses and 1.0 per 100 FTE aides. Medical procedures contributing to sharps injuries were injecting medications, administering fingersticks and heelsticks, and drawing blood. Other contributing factors were sharps disposal, contact with waste, and patient handling. Sharps with safety features frequently were not used. Underreporting of sharps injuries to the workplace-based surveillance system was estimated to be about 50%. Conclusions. Sharps injuries and other blood and body fluid exposures are serious hazards for home health care nurses and aides. Improvements in hazard intervention are needed. PMID:19890177

Needlestick and Sharps Injuries in Dermatologic Surgery: A Review of Preventative Techniques and Post-exposure Protocols

PubMed Central

Monroe, Holly; Orengo, Ida; Rosen, Theodore

2016-01-01

Background: Needlestickand sharps injuries are the leading causes of morbidity in the dermatologicfield. Among medical specialties, surgeons and dermatologists have the highest rates of needlestickand sharps injuries.The high rates of needlestickand sharps injuries in dermatology not only apply to physicians, but also to nurses, physician assistants, and technicians in the demnatologic field. Needlestickand sharps injuries are of great concern due to the monetary, opportunity, social, and emotional costs associated with their occurrence. Objective: A review of preventative techniques and post-exposure protocols for the majortypes of sharps injuries encountered in dermatologic practice. Design: The terms “needle-stick injuryT’sharps injuryTdermatologic surgery? “post-exposure prophylaxis,”and “health-care associated injury” were used in combinations to search the PubMed database. Relevant studies were reviewed for validity and included. Results The authors discuss the major types of sharps injuries that occur in the dermatologic surgery setting and summarize preventative techniques with respect to each type of sharps injury.The authors also summarize and discuss relevant post-exposure protocols in the event of a sharps injury. Conclusion: The adoption of the discussed methods, techniques, practices, and attire can result in the elimination of the vast majority of dermatologic sharps injuries. PMID:27847548

Overview of the SHARP campaign: Motivation, design, and major outcomes

NASA Astrophysics Data System (ADS)

Olaguer, Eduardo P.; Kolb, Charles E.; Lefer, Barry; Rappenglück, Bernhard; Zhang, Renyi; Pinto, Joseph P.

2014-03-01

The Study of Houston Atmospheric Radical Precursors (SHARP) was a field campaign developed by the Houston Advanced Research Center on behalf of the Texas Environmental Research Consortium. SHARP capitalized on previous research associated with the Second Texas Air Quality Study and the development of the State Implementation Plan (SIP) for the Houston-Galveston-Brazoria (HGB) ozone nonattainment area. These earlier studies pointed to an apparent deficit in ozone production in the SIP attainment demonstration model despite the enhancement of simulated emissions of highly reactive volatile organic compounds in accordance with the findings of the original Texas Air Quality Study in 2000. The scientific hypothesis underlying the SHARP campaign was that there are significant undercounted primary and secondary sources of the radical precursors, formaldehyde, and nitrous acid, in both heavily industrialized and more typical urban areas of Houston. These sources, if properly taken into account, could increase the production of ozone in the SIP model and the simulated efficacy of control strategies designed to bring the HGB area into ozone attainment. This overview summarizes the precursor studies and motivations behind SHARP, as well as the overall experimental design and major findings of the 2009 field campaign. These findings include significant combustion sources of formaldehyde at levels greater than accounted for in current point source emission inventories; the underestimation of formaldehyde and nitrous acid emissions, as well as CO/NOx and NO2/NOx ratios, by mobile source models; and the enhancement of nitrous acid by atmospheric organic aerosol.

Sharp Dissection versus Electrocautery for Radial Artery Harvesting

PubMed Central

Marzban, Mehrab; Arya, Reza; Mandegar, Mohammad Hossein; Karimi, Abbas Ali; Abbasi, Kiomars; Movahed, Namvar; Abbasi, Seyed Hesameddin

2006-01-01

Radial arteries have been increasingly used during the last decade as conduits for coronary artery revascularization. Although various harvesting techniques have been described, there has been little comparative study of arterial damage and patency. A radial artery graft was used in 44 consecutive patients, who were randomly divided into 2 groups. In the 1st group, the radial artery was harvested by sharp dissection and in the 2nd, by electrocautery. These groups were compared with regard to radial artery free flow, harvest time, number of clips used, complications, and endothelial damage. Radial artery free flow before and after intraluminal administration of papaverine was significantly greater in the electrocautery group (84.3 ± 50.7 mL/min and 109.7 ± 68.5 mL/min) than in the sharp-dissection group (52.9 ± 18.3 mL/min and 69.6 ± 28.2 mL/ min) (P =0.003). Harvesting time by electrocautery was significantly shorter (25.4 ± 4.3 min vs 34.4 ± 5.9 min) (P =0.0001). Electrocautery consumed an average of 9.76 clips, versus 22.45 clips consumed by sharp dissection. The 2 groups were not different regarding postoperative complications, except for 3 cases of temporary paresthesia of the thumb in the electrocautery group; histopathologic examination found no endothelial damage. We conclude that radial artery harvesting by electrocautery is faster and more economical than harvesting by sharp dissection and is associated with better intraoperative flow and good preservation of endothelial integrity. PMID:16572861

Scintillator high-gain avalanche rushing photoconductor active-matrix flat panel imager: Zero-spatial frequency x-ray imaging properties of the solid-state SHARP sensor structure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wronski, M.; Zhao, W.; Tanioka, K.

Purpose: The authors are investigating the feasibility of a new type of solid-state x-ray imaging sensor with programmable avalanche gain: scintillator high-gain avalanche rushing photoconductor active matrix flat panel imager (SHARP-AMFPI). The purpose of the present work is to investigate the inherent x-ray detection properties of SHARP and demonstrate its wide dynamic range through programmable gain. Methods: A distributed resistive layer (DRL) was developed to maintain stable avalanche gain operation in a solid-state HARP. The signal and noise properties of the HARP-DRL for optical photon detection were investigated as a function of avalanche gain both theoretically and experimentally, and themore » results were compared with HARP tube (with electron beam readout) used in previous investigations of zero spatial frequency performance of SHARP. For this new investigation, a solid-state SHARP x-ray image sensor was formed by direct optical coupling of the HARP-DRL with a structured cesium iodide (CsI) scintillator. The x-ray sensitivity of this sensor was measured as a function of avalanche gain and the results were compared with the sensitivity of HARP-DRL measured optically. The dynamic range of HARP-DRL with variable avalanche gain was investigated for the entire exposure range encountered in radiography/fluoroscopy (R/F) applications. Results: The signal from HARP-DRL as a function of electric field showed stable avalanche gain, and the noise associated with the avalanche process agrees well with theory and previous measurements from a HARP tube. This result indicates that when coupled with CsI for x-ray detection, the additional noise associated with avalanche gain in HARP-DRL is negligible. The x-ray sensitivity measurements using the SHARP sensor produced identical avalanche gain dependence on electric field as the optical measurements with HARP-DRL. Adjusting the avalanche multiplication gain in HARP-DRL enabled a very wide dynamic range which encompassed all clinically relevant medical x-ray exposures. Conclusions: This work demonstrates that the HARP-DRL sensor enables the practical implementation of a SHARP solid-state x-ray sensor capable of quantum noise limited operation throughout the entire range of clinically relevant x-ray exposures. This is an important step toward the realization of a SHARP-AMFPI x-ray flat-panel imager.« less

The Multi-Stage History of Mt. Sharp

NASA Technical Reports Server (NTRS)

Allen, C.; Dapremont, A.

2013-01-01

The Curiosity rover is exploring Gale crater and Mt. Sharp, Gale's 5-km high central mound. We are investigating the history of alteration and erosion of Mt. Sharp using orbital imagery, spectroscopy and rover observations. Our results suggest a significant time gap between emplacement of the upper and lower sections of the mound. Crater counts show that the lower mound was formed soon after Gale itself, and that it contains distinct units ranging in altitude from approximately -4,500 to -1,800 m. Spectral data suggest that many units contain phyllosilicates. We found that these clay-bearing rocks occur in distinct layers concentrated below -2,900 m. Parts of the lower mound exhibit a transition from clays to sulfates with increasing altitude. The lower mound shows evidence of flowing water, including canyons and inverted channels. Wind erosion produced km-scale yardangs and scalloped cliffs. Our mapping shows that many yardangs in the lower mound are clay-bearing, with a predominant orientation of around N-S. Curiosity's ground-level images show myriad fine-scale, mainly horizontal layers in the lower mound. The rover has found stream beds and conglomerates, indicating that water once flowed on the crater floor. Drilling near the deepest point in Gale produced abundant clay, providing additional evidence of aqueous alteration. Upper mound units range in altitude from -2,100 m to +500 m, and mantle the lower mound above an angular unconformity. Most upper mound units are composed of layers. The formation age of the upper mound is unknown, since few craters are preserved. Clay-bearing layers are detectable in several locations, mainly at altitudes near -2,000 m. There is no evidence of water flow, but wind erosion has scalloped the surfaces and edges of layers, and fine-scale yardangs are common. Correlations between yardangs and clay spectra are apparent only in the lowermost units of the upper mound. Yardang orientations vary, and include N-S, NW-SE, and NE-SW. Upper mound units resemble the planet-wide Medusae Fossae formation, dated as Hesperian and argued to be composed of ignimbrites. Medusae Fossae layers are easily eroded by wind, and our mapping demonstrates their resemblance to upper mound fine-scale yardangs. The history of Mt. Sharp started with deposition and lithification of sediments shortly after crater formation. Some lower mound layers were partially altered to clays and sulfates, and water formed streams and canyons. Wind erosion of the lower mound produced large-scale yardangs, particularly in clay-rich layers, oriented generally N-S. Upper mound units were emplaced following a considerable period of wind erosion. The absence of water flow on the upper mound suggests that these units were emplaced after atmospheric loss rendered water unstable at the surface. The shift in dominant wind direction, as indicated by yardang orientations, also argues for a time gap between erosion of the lower and upper mound. These observations are consistent with upper mound units being related to the Hesperian Medusae Fossae formation. During 2014 Curiosity is expected to reach the foot of Mt. Sharp and ascend through the clay-rich layers, into the sulfate-rich layers, and possibly past the interface with the upper mound. This will be a unique opportunity to field check geologic models on the surface of Mars.

Consistency relations for sharp inflationary non-Gaussian features

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mooij, Sander; Palma, Gonzalo A.; Panotopoulos, Grigoris

If cosmic inflation suffered tiny time-dependent deviations from the slow-roll regime, these would induce the existence of small scale-dependent features imprinted in the primordial spectra, with their shapes and sizes revealing information about the physics that produced them. Small sharp features could be suppressed at the level of the two-point correlation function, making them undetectable in the power spectrum, but could be amplified at the level of the three-point correlation function, offering us a window of opportunity to uncover them in the non-Gaussian bispectrum. In this article, we show that sharp features may be analyzed using only data coming frommore » the three point correlation function parametrizing primordial non-Gaussianity. More precisely, we show that if features appear in a particular non-Gaussian triangle configuration (e.g. equilateral, folded, squeezed), these must reappear in every other configuration according to a specific relation allowing us to correlate features across the non-Gaussian bispectrum. As a result, we offer a method to study scale-dependent features generated during inflation that depends only on data coming from measurements of non-Gaussianity, allowing us to omit data from the power spectrum.« less

WOOLLY CUSPS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nauenberg, M.; Pais, A.

1962-04-01

A study is made of the elastic scattering 1 + 2 yields 1 + 2 in the energy region where the inelastic process 1 + 2 yields 3 + 4 sets in, for the case that particle 3 is unstable. By woolly cusp'' is meant the phenomenon that corresponds to the sharp cusp in the stable case. The procedure followed is to consider the inelastic channel to be of the three-body type, where the three- body states are parametrized by a Breit-Wigner formula around a mean mass m of particle 3. The connection between a woolly and a sharp cuspmore » is made evident. The problem is studied in terms of a twochannel S-wave K matrix. In the two- channel approximation the woolly cusp necessarily shows a decrease in the elastic cross section sigma above a characteristic energy. As a function of energy, sigma must either show a maximum or an inflection point. In either case, the energy at which this happens may lie above or below the inelastic threshold for the fictitious case that particle 3 has a sharp mass m. The sign and magnitude of the elastic scattering phase shift at this m point'' approximately determines which case is actually realized. (auth)« less

Statistical features of hypnagogic EEG measured by a new scoring system.

PubMed

Tanaka, H; Hayashi, M; Hori, T

1996-11-01

The purpose of this study was to examine the durations of individual occurrences of each of nine hypnagogic electroencephalographic (EEG) stages and the interchange relationship among these stages. Most of the alpha patterns (stages 1, 2, and 3), ripples (stage 5), and spindles (stage 9) tended to last > 2 minutes. On the other hand, histograms of the durations of time in EEG flattening (stage 4) and vertex sharp wave (stages 6, 7, and 8) patterns had peaks that lasted < 30 seconds. Analysis of the sequences of EEG stage changes demonstrated that shifts to adjacent stages were most common for all stages. A smooth change in EEG stage occurred in the downward or upward direction in the hypnagogic state. This was especially true for the first five stages. EEG stages with vertex sharp waves (stages 6, 7, and 8), however, showed less-smooth changes, with approximately 20% of all changes involving a jump of more than one stage. These results show that the basic EEG activities in the sleep onset period are the alpha, theta, and sleep spindles activities, whereas the activities of vertex sharp waves seem to have a secondary or enhancing role, instead of independent characteristics.

Spouses’ Attachment Pairings Predict Neuroendocrine, Behavioral, and Psychological Responses to Marital Conflict

PubMed Central

Beck, Lindsey A.; Pietromonaco, Paula R.; DeBuse, Casey J.; Powers, Sally I.; Sayer, Aline G.

2014-01-01

This research investigated how spouses’ attachment styles jointly contributed to their stress responses. Newlywed couples discussed relationship conflicts. Salivary cortisol indexed physiological stress; observer-rated behaviors indexed behavioral stress; self-reported distress indexed psychological stress. Multilevel modeling tested predictions that couples including one anxious and one avoidant partner or two anxious partners would show distinctive stress responses. As predicted, couples with anxious wives and avoidant husbands showed physiological reactivity in anticipation of conflict: Both spouses showed sharp increases in cortisol, followed by rapid declines. These couples also showed distinctive behaviors during conflict: Anxious wives had difficulty recognizing avoidant husbands’ distress, and avoidant husbands had difficulty approaching anxious wives for support. Contrary to predictions, couples including two anxious partners did not show distinctive stress responses. Findings suggest that the fit between partners’ attachment styles can improve understanding of relationships by specifying conditions under which partners’ attachment characteristics jointly influence individual and relationship outcomes. PMID:23773048

How Financial Incentives Induce Disability Insurance Recipients to Return to Work.

PubMed

Kostol, Andreas Ravndal; Mogstad, Magne

2014-02-01

Using a local randomized experiment that arises from a sharp discontinuity in Disability Insurance (DI) policy in Norway, we provide transparent and credible identification of how financial incentives induce DI recipients to return to work. We find that many DI recipients have considerable capacity to work that can be effectively induced by providing financial work incentives. We further show that providing work incentives to DI recipients may both increase their disposable income and reduce program costs. Our findings also suggest that targeted policies may be the most effective in encouraging DI recipients to return to work.

Near optimal pentamodes as a tool for guiding stress while minimizing compliance in 3d-printed materials: A complete solution to the weak G-closure problem for 3d-printed materials

NASA Astrophysics Data System (ADS)

Milton, Graeme W.; Camar-Eddine, Mohamed

2018-05-01

For a composite containing one isotropic elastic material, with positive Lame moduli, and void, with the elastic material occupying a prescribed volume fraction f, and with the composite being subject to an average stress, σ0 , Gibiansky, Cherkaev, and Allaire provided a sharp lower bound Wf(σ0) on the minimum compliance energy σ0 :ɛ0 , in which ɛ0 is the average strain. Here we show these bounds also provide sharp bounds on the possible (σ0 ,ɛ0) -pairs that can coexist in such composites, and thus solve the weak G-closure problem for 3d-printed materials. The materials we use to achieve the extremal (σ0 ,ɛ0) -pairs are denoted as near optimal pentamodes. We also consider two-phase composites containing this isotropic elasticity material and a rigid phase with the elastic material occupying a prescribed volume fraction f, and with the composite being subject to an average strain, ɛ0. For such composites, Allaire and Kohn provided a sharp lower bound W˜f(ɛ0) on the minimum elastic energy σ0 :ɛ0 . We show that these bounds also provide sharp bounds on the possible (σ0 ,ɛ0) -pairs that can coexist in such composites of the elastic and rigid phases, and thus solve the weak G-closure problem in this case too. The materials we use to achieve these extremal (σ0 ,ɛ0) -pairs are denoted as near optimal unimodes.

Creutzfeldt-Jakob Disease-Like Periodic Sharp Wave Complexes in Voltage-Gated Potassium Channel-Complex Antibodies Encephalitis: A Case Report.

PubMed

Savard, Martin; Irani, Sarosh R; Guillemette, Annie; Gosselin-Lefebvre, Stéphanie; Geschwind, Michael; Jansen, Gerard H; Gould, Peter V; Laforce, Robert

2016-02-01

Voltage-gated potassium channel-complex antibodies (VGKC-cAbs) encephalitis, a treatable autoantibody encephalopathy, has been previously reported to clinically mimic sporadic Creutzfeldt-Jakob disease. Among available clinical clues to distinguish them, periodic sharp wave complexes, a typical finding in sporadic Creutzfeldt-Jakob disease, have never been reported in association with VGKC-cAbs encephalitis. A 76-year-old man was transferred to a tertiary neurology center with a clinical history of 6-month weight loss, cognitive disturbance, and nonspecific generalized weakness. He had two seizures the month before transfer and then evolved to severe encephalopathy, requiring mechanical ventilation. Periodic sharp wave complexes every 1 to 2 seconds over slowed background were found on EEG, and MRI showed cerebellar and bifrontal cortical T2/FLAIR/DWI hypersignal without restricted diffusion on ADC mapping. Pancorporal positron emission tomography scan was negative. An immunotherapy trial did not improve the patient condition. Therefore, he died after life support withdrawal. Brain autopsy revealed mononuclear neocortex infiltrate without significant spongiosis, and the anti-VGKC test showed a seropositivity of 336 pmol/L (normal, 0-31), 3 month after the patient deceased. This is the first reported case of VGKC-cAbs encephalitis associated with periodic sharp wave complexes on EEG, which further confuse the differential diagnosis with sporadic Creutzfeldt-Jakob disease. However, the cortical DWI hypersignal without restriction seems to remain a way to discriminate these two entities appropriately, when present. These clues are of paramount importance because VGKC-cAbs encephalitis is a treatable disease.

Detailed modeling of electron emission for transpiration cooling of hypersonic vehicles

NASA Astrophysics Data System (ADS)

Hanquist, Kyle M.; Hara, Kentaro; Boyd, Iain D.

2017-02-01

Electron transpiration cooling (ETC) is a recently proposed approach to manage the high heating loads experienced at the sharp leading edges of hypersonic vehicles. Computational fluid dynamics (CFD) can be used to investigate the feasibility of ETC in a hypersonic environment. A modeling approach is presented for ETC, which includes developing the boundary conditions for electron emission from the surface, accounting for the space-charge limit effects of the near-wall plasma sheath. The space-charge limit models are assessed using 1D direct-kinetic plasma sheath simulations, taking into account the thermionically emitted electrons from the surface. The simulations agree well with the space-charge limit theory proposed by Takamura et al. for emitted electrons with a finite temperature, especially at low values of wall bias, which validates the use of the theoretical model for the hypersonic CFD code. The CFD code with the analytical sheath models is then used for a test case typical of a leading edge radius in a hypersonic flight environment. The CFD results show that ETC can lower the surface temperature of sharp leading edges of hypersonic vehicles, especially at higher velocities, due to the increase in ionized species enabling higher electron heat extraction from the surface. The CFD results also show that space-charge limit effects can limit the ETC reduction of surface temperatures, in comparison to thermionic emission assuming no effects of the electric field within the sheath.

Storage change in a flat-lying fracture during well tests

NASA Astrophysics Data System (ADS)

Murdoch, Lawrence C.; Germanovich, Leonid N.

2012-12-01

The volume of water released from storage per unit head drop per volume of an REV is a basic quantity in groundwater hydrology, but the details of the process of storage change in the vicinity of a well are commonly overlooked. We characterize storage change in a flat-lying fracture or thin sedimentary bed through the apparent hydraulic compliance,Cf, the change in aperture of the fracture or thickness of the layer per unit change in pressure. The results of theoretical analyses and field measurements show that Cf increases with time near the well during pumping, but it drops suddenly and may become negative at the beginning of recovery during a well test. Profiles of Cfincrease with radial distance from a well, but they are marked by a sharp increase and a sharp decrease at the edge of the region affected by the wellbore pressure transient. The conventional view in groundwater hydrology is that storage change at a point is proportional to the local change in pressure, which requires that the hydraulic compliance is uniform and constant. It appears that this conventional view is a simplification of a process that varies in both space and time and can even take on negative values. This simplification may be a source of uncertainty when interpreting well tests and extensometer records or predicting long-term well performance.

Electroosmotic flow mixing in zigzag microchannels.

PubMed

Chen, Jia-Kun; Yang, Ruey-Jen

2007-03-01

In this study we performed numerical and experimental investigations into the mixing of EOFs in zigzag microchannels with two different corner geometries, namely sharp corners and flat corners. In the zigzag microchannel with sharp corners, the flow travels more rapidly near the inner wall of the corner than near the outer wall as a result of the higher electric potential drop. The resulting velocity gradient induces a racetrack effect, which enhances diffusion within the fluid and hence improves the mixing performance. The simulation results reveal that the mixing index is approximately 88.83%. However, the sharp-corner geometry causes residual liquid or bubbles to become trapped in the channel at the point where the flow is almost stationary, when the channel is in the process of cleaning. Accordingly, a zigzag microchannel with flat-corner geometry is developed. The flat-corner geometry forms a convergent-divergent type nozzle which not only enhances the mixing performance in the channel, but also prevents the accumulation of residual liquid or bubbles. Scaling analysis reveals that this corner geometry leads to an effective increase in the mixing length. The experimental results reveal that the mixing index is increased to 94.30% in the flat-corner zigzag channel. Hence, the results demonstrate that the mixing index of the flat-corner zigzag channel is better than that of the conventional sharp-corner microchannel. Finally, the results of Taguchi analysis indicate that the attainable mixing index is determined primarily by the number of corners in the microchannel and by the flow passing height at each corner.

Solar flare induced D-region ionospheric perturbations evaluated from VLF measurements

NASA Astrophysics Data System (ADS)

Singh, Ashutosh K.; Singh, A. K.; Singh, Rajesh; Singh, R. P.

2014-03-01

The results of very low frequency (VLF) wave amplitude measurements carried out at the low latitude station Varanasi (geom. lat. 14∘55'N, long. 154∘E), India during solar flares are presented for the first time. The VLF waves (19.8 kHz) transmitted from the NWC-transmitter, Australia propagated in the Earth-ionosphere waveguide to long distances and were recorded at Varanasi. Data are analyzed and the reflection height H' and the sharpness factor β are evaluated. It is found that the reflection height decreases whereas sharpness factor increases with the increase of solar flare power. The H' is found to be higher and β smaller at low latitudes than the corresponding values at mid and high latitudes. The sunspot numbers were low during the considered period 2011-2012, being the rising phase of solar cycle 24 and as a result cosmic rays may impact the D-region ionosphere. The increased ionization from the flare lowers the effective reflecting height, H', of the D-region roughly in proportion to the logarithm of the X-ray flare intensity from a typical mid-day unperturbed value of about 71-72 km down to about 65 km for an X class flare. The sharpness ( β) of the lower edge of the D-region is also significantly increased by the flare but reaches a clear saturation value of about 0.48 km-1 for flares of magnitude greater than about X1 class.

Misinterpretation of lateral acoustic variations on high-resolution seismic reflection profiles as fault offsets of Holocene bay mud beneath the southern part of San Francisco Bay, California

USGS Publications Warehouse

Marlow, M. S.; Hart, P.E.; Carlson, P.R.; Childs, J. R.; Mann, D. M.; Anima, R.J.; Kayen, R.E.

1996-01-01

We collected high-resolution seismic reflection profiles in the southern part of San Francisco Bay in 1992 and 1993 to investigate possible Holocene faulting along postulated transbay bedrock fault zones. The initial analog records show apparent offsets of reflection packages along sharp vertical boundaries. These records were originally interpreted as showing a complex series of faults along closely spaced, sharp vertical boundaries in the upper 10 m (0.013 s two-way travel time) of Holocene bay mud. A subsequent survey in 1994 was run with a different seismic reflection system, which utilized a higher power source. This second system generated records with deeper penetration (max. 20 m, 0.026 s two-way travel time) and demonstrated that the reflections originally interpreted as fault offsets by faulting were actually laterally continuous reflection horizons. The pitfall in the original interpretations was caused by lateral variations in the amplitude brightness of reflection events, coupled with a long (greater than 15 ms) source signature of the low-power system. These effects combined to show apparent offsets of reflection packages along sharp vertical boundaries. These boundaries, as shown by the second system, in fact occur where the reflection amplitude diminishes abruptly on laterally continuous reflection events. This striking lateral variation in reflection amplitude is attributable to the localized presence of biogenic(?) gas.

Dawn LAMO Image 83

NASA Image and Video Library

2016-05-06

Ceres densely cratered landscape is revealed in this image taken by the framing camera aboard NASA Dawn spacecraft. The craters show various degrees of degradation. The youngest craters have sharp rims.

Dawn LAMO Image 84

NASA Image and Video Library

2016-05-09

Ceres densely cratered landscape is revealed in this image taken by the framing camera aboard NASA Dawn spacecraft. The craters show various degrees of degradation. The youngest craters have sharp rims.

Sharp acoustic vortex focusing by Fresnel-spiral zone plates

NASA Astrophysics Data System (ADS)

Jiménez, Noé; Romero-García, Vicent; García-Raffi, Luis M.; Camarena, Francisco; Staliunas, Kestutis

2018-05-01

We report the optimal focusing of acoustic vortex beams by using flat lenses based on a Fresnel-spiral diffraction grating. The flat lenses are designed by spiral-shaped Fresnel zone plates composed of one or several arms. The constructive and destructive interferences of the diffracted waves by the spiral grating result in sharp acoustic vortex beams, following the focal laws obtained in analogy with the Fresnel zone plate lenses. In addition, we show that the number of arms determines the topological charge of the vortex, allowing the precise manipulation of the acoustic wave field by flat lenses. The experimental results in the ultrasonic regime show excellent agreement with the theory and full-wave numerical simulations. A comparison with beam focusing by Archimedean spirals also showing vortex focusing is given. The results of this work may have potential applications for particle trapping, ultrasound therapy, imaging, or underwater acoustic transmitters.

Branching, Superdiffusion and Stress Relaxation in Surfactant Micelles

NASA Astrophysics Data System (ADS)

Sureshkumar, R.; Dhakal, S.; Syracuse University Team

2016-11-01

We investigate the mechanism of branch formation and its effects on the dynamics and rheology of a model cationic micellar fluid using molecular dynamics (MD) simulations. Branched structures are formed upon increasing counter ion density. A sharp decrease in the solution viscosity with increasing salinity has long been attributed to the sliding motion of micellar branches along the main chain. Simulations not only provide firm evidence of branch sliding in real time, but also show enhanced diffusion of surfactants by virtue of such motion. Insights into the mechanism of stress relaxation associated with branch sliding will be discussed. Specifically, an externally imposed stress damps out more quickly in a branched system compared to that in an unbranched one. NSF Grants 1049489, 1049454.

Polycrystalline elastic moduli of a high-entropy alloy at cryogenic temperatures

DOE PAGES

Haglund, A.; Koehler, M.; Catoor, D.; ...

2014-12-05

A FCC high-entropy alloy (HEA) that exhibits strong temperature dependence of strength at low homologous temperatures in sharp contrast to pure FCC metals like Ni that show weak temperature dependence is CrMnCoFeNi. In order to understand this behavior, elastic constants were determined as a function of temperature. From 300 K down to 55 K, the shear modulus (G) of the HEA changes by only 8%, increasing from 80 to 86 GPa. Moreover, this temperature dependence is weaker than that of FCC Ni, whose G increases by 12% (81–91 GPa). Therefore, the uncharacteristic temperature-dependence of the strength of the HEA ismore » not due to the temperature dependence of its shear modulus.« less

SHARP-B2: Flight Test Objectives, Project Implementation and Initial Results

NASA Technical Reports Server (NTRS)

Salute, Joan; Bull, Jeff; Rasky, Dan; Keese, David; Arnold, Jim (Technical Monitor)

2001-01-01

On September 28, 2000 the SHARP-B2 flight experiment was launched from Vandenberg Air Force Base, California. SHARP-B2 is the 2nd Ballistic flight test in the SHARP (Slender Hypervelocity Aerothermodynamic Research Probes) program which develops and tests new thermal protection materials and sharp body concepts. The flight tested Ultra-High Temperature Ceramics (UHTCs), which may radically change the design and performance of future aerospace vehicles. The new designs may overturn an age-old tenet of aerodynamics: that blunt-body aerospace vehicles, but not those with sharp leading edges, can survive the searing temperatures created as the vehicles tear through the atmosphere. Sharp leading edges offer numerous advantages over the blunt-body design currently in use. They could allow a space shuttle or crew return vehicle to maneuver in space more like an airplane and potentially allow astronauts to return to Earth from anywhere on orbit. They may allow improved astronaut safety by decreasing the risk of aborting into the ocean. They may reduce the electromagnetic interference that causes the communications blackouts that plague reentering blunt-body space vehicles. Reducing the amount of drag could lead to a reduction in propulsion requirements. Planetary probes could make use of sharp-body technology for aerobraking and to maximize their maneuvering capability. SHARP-B2 was a joint effort among NASA Ames, Sandia National Laboratories, the U.S. Air Force and the U.S. Army. It was funded by the Pathfinder Program at NASA's Marshall Space Flight Center. The SHARP-B2 payload was carried aboard a U.S. Air Force Minuteman III missile carrying a modified Mk 12A reentry vehicle (RV), which blasted off from Vandenberg Air Force Base near Lompoc, CA, at 3:01 a.m. PDT on Sept. 28. The RV was equipped with four 5. 1 inch-long strakes, or sharp leading edges. Each strake contained three UHTCs: ZrB2/SiC/C; ZrB2/SiC; and HfB2/SiC. Once it reached an altitude of about 400 nautical miles, the RV was released, returning through Earth's atmosphere at speeds exceeding Mach 22. One pair of strakes was designed to retract just before reaching temperatures high enough to cause the material to begin ablating. The other pair was designed to retract shortly after ablation began, at an expected temperature of nearly 5,100 degrees Fahrenheit. Sensors in the strakes measured how closely performance matched pre-flight calculations, and data was successfully collected throughout the 23-minute flight. A parachute was deployed (but not fully inflated) and the RV splashed down in a lagoon at the Kwajalein missile range in the Pacific Ocean. Within 3 hours radar track analysis showed ocean entry to be precisely at the latitude/longitude coordinates estimated during pre-flight simulation. An hour later a ship was deployed by the Army to recover the reentry vehicle, which was recovered in 165 feet of water, just 500 feet from its planned splash-down point. This is the first RV recovery in over a decade.

Characterization of carbonaceous matter in xenolithic clasts from the Sharps (H3.4) meteorite: Constraints on the origin and thermal processing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kebukawa, Yoko; Zolensky, Michael E.; Chan, Queenie H. S.

Primitive xenolithic clasts, often referred to as “dark clasts”, are well known in many regolith breccias. The Sharps H3.4 ordinary chondrite contains unusually large dark clasts up to ~1 cm across. Poorly-graphitized carbon (PGC), with Fe, Ni metal and described as “carbon-rich aggregates”, has been found in these clasts (Brearley, 1990). We report detailed analyses of carbonaceous matter in several identical Sharps clasts using FTIR, Raman, C-XANES, and TEM that provide insight on the extent of thermal processing and possible origin of such clasts. We also prepared acid residues of the clasts using the HCl/HF method and conducted mass spectrometric analysismore » of the entrained noble gases. Carbonaceous matter is often used to infer thermal history due to its sensitivity to thermal processes. The FTIR spectra of the acid residue from the Sharps clast suggest that carbonaceous matter in the clast contains less hydrogen and oxygen compared to acid residues from typical type 3.4 ordinary chondrites. The metamorphic temperatures obtained by Raman spectroscopy ranges between ~380 °C and ~490 °C. TEM observations indicate that the clasts experienced a peak temperature of 300 °C to 400 °C, based on the carbon d 002 layer lattice spacing of C-rich aggregates. These estimates are consistent with an earlier estimate of 330 ± 50 °C, that is also estimated by the d 002 layer lattice spacing (Brearley, 1990). It should be noted that the lattice spacing thermometer is based on terrestrial metamorphose rocks, and thus temperature was probably underestimated. Meanwhile, the C-XANES spectra of the C-rich aggregates show high exciton intensities, indicative of graphene structures that developed at around 700–800 °C following an extensive period of time (millions of years), however, the surrounding matrix areas experienced lower temperatures of less than 300–500 °C. Noble gas analysis of the acid residue from the Sharps clasts shows that the residue is almost identical with some material reported in carbonaceous chondrites, i.e., heavily enriched in the Q-gas component as well as HL-gas from presolar diamonds and Ne-E(H) from presolar SiC. These results indicate that the C-rich aggregates in the Sharps clasts formed under relatively high temperature conditions, up to 800 °C, and were subsequently mixed with lower temperature matrix, probably in a different parent body, before they were incorporated into the final Sharps lithology by collision.« less

Spacecraft Health Automated Reasoning Prototype (SHARP): The fiscal year 1989 SHARP portability evaluations task for NASA Solar System Exploration Division's Voyager project

NASA Technical Reports Server (NTRS)

Atkinson, David J.; Doyle, Richard J.; James, Mark L.; Kaufman, Tim; Martin, R. Gaius

1990-01-01

A Spacecraft Health Automated Reasoning Prototype (SHARP) portability study is presented. Some specific progress is described on the portability studies, plans for technology transfer, and potential applications of SHARP and related artificial intelligence technology to telescience operations. The application of SHARP to Voyager telecommunications was a proof-of-capability demonstration of artificial intelligence as applied to the problem of real time monitoring functions in planetary mission operations. An overview of the design and functional description of the SHARP system is also presented as it was applied to Voyager.

A promptly approach from monosaccharides of biomass to oligosaccharides via sharp-quenching thermo conversion (SQTC).

PubMed

Liu, Xiao; Wei, Weiqi; Wu, Shubin; Lei, Ming; Liu, Ying

2018-06-01

In this study, a novel and facile approach of conversion monosaccharides (glucose and xylose) to oligosaccharides (Cello-oligosaccharides and Xylo-oligosaccharides) was demonstrated. The approach did not introduce any chemical reagent and the preparation process could be environmentally friendly. Identification and quantification by ion chromatography (IC) and high performance liquid chromatography (HPLC) showed that the yields of COS and XOS reached to 44.62% (38 s) and 47.09% (30 s) respectively at 500 °C reaction temperature coupled with sharp-quenching method. Structural characterization indicated that such oligosaccharides showed a degree of polymerization (DP) with 2-6, and the units mainly linked by β-(1 → 4)-glycosidic bond. Copyright © 2018 Elsevier Ltd. All rights reserved.

Impact Theory of Mass Extinctions and the Invertebrate Fossil Record

NASA Astrophysics Data System (ADS)

Alvarez, Walter; Kauffman, Erle G.; Surlyk, Finn; Alvarez, Luis W.; Asaro, Frank; Michel, Helen V.

1984-03-01

There is much evidence that the Cretaceous-Tertiary boundary was marked by a massive meteorite impact. Theoretical consideration of the consequences of such an impact predicts sharp extinctions in many groups of animals precisely at the boundary. Paleontological data clearly show gradual declines in diversity over the last 1 to 10 million years in various invertebrate groups. Reexamination of data from careful studies of the best sections shows that, in addition to undergoing the decline, four groups (ammonites, cheilostomate bryozoans, brachiopods, and bivalves) were affected by sudden truncations precisely at the iridium anomaly that marks the boundary. The paleontological record thus bears witness to terminal-Cretaceous extinctions on two time scales: a slow decline unrelated to the impact and a sharp truncation synchronous with and probably caused by the impact.

Variability of dayside electron temperature at Venus

NASA Technical Reports Server (NTRS)

Mahajan, K. K.; Ghosh, S.; Paul, R.; Hoegy, W. R.

1994-01-01

Langmuir probe measurements on Pioneer Venus Orbiter show that electron temperature (Te) profiles exhibit two distinct regions. The lower, but more extended region is in the main ionosphere where Te increases slowly with altitude. The other, less extended region is in the ionopause, where Te rise sharply with altitude. If horizontal magnetic fields and flux ropes in the ionosphere inhibit vertical thermal conductivity sufficiently, then the observed Te profile could be explained with EUV as the major heat source (Cravens et al., 1980). The rise in Te in the ionopause region has generally been attributed to solar wind heating (Brace and Kliore, 1991). We suggest that this sharp rise in Te is due primarily to the steep fall in electron density, Ne. If the heating rate is essentially unchanged and heat conduction is not of primary importance, then a steep rise in Te will maintain a constant electron cooling rate for a steeply falling Ne. We have observed large orbit to orbit variations in Te in the ionopause region which are found to be inversely related to changes in Ne. Variations in solar wind dynamic pressure do not seem to have a direct effect on Te, rather the effect is indirect coming through the sharp decrease in Ne.

Closed-form solution of decomposable stochastic models

NASA Technical Reports Server (NTRS)

Sjogren, Jon A.

1990-01-01

Markov and semi-Markov processes are increasingly being used in the modeling of complex reconfigurable systems (fault tolerant computers). The estimation of the reliability (or some measure of performance) of the system reduces to solving the process for its state probabilities. Such a model may exhibit numerous states and complicated transition distributions, contributing to an expensive and numerically delicate solution procedure. Thus, when a system exhibits a decomposition property, either structurally (autonomous subsystems), or behaviorally (component failure versus reconfiguration), it is desirable to exploit this decomposition in the reliability calculation. In interesting cases there can be failure states which arise from non-failure states of the subsystems. Equations are presented which allow the computation of failure probabilities of the total (combined) model without requiring a complete solution of the combined model. This material is presented within the context of closed-form functional representation of probabilities as utilized in the Symbolic Hierarchical Automated Reliability and Performance Evaluator (SHARPE) tool. The techniques adopted enable one to compute such probability functions for a much wider class of systems at a reduced computational cost. Several examples show how the method is used, especially in enhancing the versatility of the SHARPE tool.

Solute transport by flow yields geometric shocks in shape evolution

NASA Astrophysics Data System (ADS)

Huang, Jinzi (Mac); Davies Wykes, Megan; Hajjar, George; Ristroph, Leif; Shelley, Michael

2017-11-01

Geological processes such as erosion and dissolution of surfaces often lead to striking shapes with strikingly sharp features. We present observations of such features forming in dissolution under gravity. In our experiment, a dissolving body with initially smooth surface evolves into an increasingly sharp needle shape. A mathematical model of its shape dynamics, derived from a boundary layer theory, predicts that a geometric shock forms at the tip of dissolved body, with the tip curvature becoming infinite in finite time. We further discuss the model's application to similar processes, such as flow driven erosion which can yield corners.

Measurements of Thermal Effects on Acoustic Screech in a Choked Circular Jet Emanating from a Sharp-Edged Orifice

NASA Technical Reports Server (NTRS)

Kandula, Max

2012-01-01

Experiments are performed in a 24.4 mm diameter choked circular hot and cold jets issuing from a sharp-edged orifice at a fully expanded jet Mach number of 1.85. The stagnation temperature of the hot and the cold jets are 319 K and 299 K respectively. The results suggest that temperature effects on the screech amplitude and frequency are manifested for the fundamental, with a reduced amplitude and increased frequency for hot jet relative to the cold jet. Temperature effects on the second harmonic are also observed.

An Investigation of the Effects of Nose and Lip Shapes for an Underslung Scoop Inlet at Mach Numbers from 0 to 1.9

NASA Technical Reports Server (NTRS)

Pfyl, Frank A.

1955-01-01

An experimental investigation was conducted to determine the performance characteristics an underslung nose-scoop air-induction system for a supersonic airplane. Five different nose shapes, three lip shapes, and two internal diffusers were investigated. Tests were made at Mach numbers from 0 to 1.9, angles of attack from 0 deg to approximately l5 deg, and mass-flow ratios from 0 to maximum obtainable. It was found that the underslung nose-scoop inlet was able to operate at Mach numbers from 0.6 to 1.9 over a large positive angle-of-attack range without adverse effects on the pressure recovery. Although there was no one inlet configuration that was markedly superior over the entire range of operating variables, the arrangement having a nose designed to give increased supersonic compression at low angles of attack, and a sharp lip (configuration designated N3L3) showed the most favorable performance characteristics over the supersonic Mach number range. Inlets with sizable lip radii gave satisfactory performance up to a Mach number of 1.5; however, as a result of an increase in drag, the performance of such inlets was markedly inferior to the sharp-lip configuration above Mach numbers of 1.5. Throughout the range of test Mach numbers all inlet configurations evidenced stable air-flow characteristics over the mass-flow range for normal engine operation. Analysis of the inlet performance on the basis of a propulsive thrust parameter showed that a fixed inlet area could be used for Mach numbers up to 1.5 with only a small sacrifice in performance.

Synthesis and Photoluminescence Properties of BaWO4:RE3+ (RE = Eu or Sm) Phosphors

NASA Astrophysics Data System (ADS)

Cho, Shinho

2018-04-01

BaWO4:RE3+ (RE = Eu or Sm) phosphor powders were prepared with different doping concentrations of the activator ion by using the conventional solid-state reaction method. The dependences in the crystal structure, luminescence intensity, and morphology on the Eu3+ and the Sm3+ concentrations in BaWO4 were investigated using X-ray diffraction (XRD), photoluminescence spectrophotometry, and scanning electron microscopy (SEM), respectively. XRD analysis showed tetragonal BaWO4 structures for all the phosphors synthesized, regardless of the type and the doping concentration of the activator ion. SEM images indicated that as the concentration of activator ions was increased, the crystalline particles showed an increasing tendency to agglomerate irregularly. The room temperature excitation spectra of Eu3+- or Sm3+-doped BaWO4 phosphors consisted of a broad charge transfer band in the ultraviolet region and several sharp 4 f-4 f transitions. When Eu3+-doped BaWO4 phosphors were excited at 274 nm, the emission spectra exhibited sharp bands due to inner shell transitions occurring from the excited energy state 5 D 0 to the lower energy levels 7 F J ( J = 1, 2, 3, and 4). For Sm3+-doped BaWO4 phosphors, three intense emission peaks at 568, 603, and 649 nm and a very weak line at 712 nm were observed. The highest asymmetry ratio-the intensity ratio of the 4 G 5/2 → 6 H 9/2 electric dipole to the 4 G 5/2 → 6 H 5/2 magnetic dipole transitions-was obtained for 1 mol% doping of Sm3+, indicating that the Sm3+ ions occupied the non-inversion symmetry sites.

Generalized Vaidya solutions and Misner-Sharp mass for n -dimensional massive gravity

NASA Astrophysics Data System (ADS)

Hu, Ya-Peng; Wu, Xin-Meng; Zhang, Hongsheng

2017-04-01

Dynamical solutions are always of interest to people in gravity theories. We derive a series of generalized Vaidya solutions in the n -dimensional de Rham-Gabadadze-Tolley massive gravity with a singular reference metric. Similar to the case of the Einstein gravity, the generalized Vaidya solution can describe shining/absorbing stars. Moreover, we also find a more general Vaidya-like solution by introducing a more generic matter field than the pure radiation in the original Vaidya spacetime. As a result, the above generalized Vaidya solution is naturally included in this Vaidya-like solution as a special case. We investigate the thermodynamics for this Vaidya-like spacetime by using the unified first law and present the generalized Misner-Sharp mass. Our results show that the generalized Minser-Sharp mass does exist in this spacetime. In addition, the usual Clausius relation δ Q =T d S holds on the apparent horizon, which implicates that the massive gravity is in a thermodynamic equilibrium state. We find that the work density vanishes for the generalized Vaidya solution, while it appears in the more general Vaidya-like solution. Furthermore, the covariant generalized Minser-Sharp mass in the n -dimensional de Rham-Gabadadze-Tolley massive gravity is also derived by taking a general metric ansatz into account.

Room temperature deposition of gold onto the diffuse and sharp diffraction spot Si(111)-( 3 × 3) R30° Au surfaces

NASA Astrophysics Data System (ADS)

Plass, Richard; Marks, Laurence D.

1996-06-01

Room temperature gold depositions onto Si(111)-( 3 × 3) R30° Au surfaces with diffuse and sharp diffraction spots [Surf. Sci. 242 (1991) 73] (diffuse and sharp 3 × 3 Au hereafter) under UHV conditions has been monitored using transmission electron diffraction (TED). Both systems display an increase in surface structure diffraction spot intensities up to the completion of 1.0 monolayer (ML) after which the surface beams display an exponential decrease in intensity with coverage. The exponential decay rate decreases after roughly 1.33 ML. These results can be attributed to gold initially diffusing to and filling 3 × 3 Au gold trimer sites in vacancy type surface domain walls [Surf. Sci. 342 (1995) 233], then filling one of three possible sites on the 3 × 3 Au structure with essentially no surface diffusion, disrupting nearby gold trimers. Gold deposition onto the diffuse type structure caused the formation and expansion of satellite arcs around the strongest 3 × 3 beams similar to those seen by others [Surf. Sci. 242 (1991) 73; Jpn. J. Appl. Phys. 16 (1977) 891; J. Vac. Sci. Technol. A 10 (1992) 3486] at elevated temperatures while the sharp structure displayed only a modest shoulder formation near the strongest 3 × 3 beams.

Sharp-Tailed Grouse Nest Survival and Nest Predator Habitat Use in North Dakota's Bakken Oil Field.

PubMed

Burr, Paul C; Robinson, Aaron C; Larsen, Randy T; Newman, Robert A; Ellis-Felege, Susan N

2017-01-01

Recent advancements in extraction technologies have resulted in rapid increases of gas and oil development across the United States and specifically in western North Dakota. This expansion of energy development has unknown influences on local wildlife populations and the ecological interactions within and among species. Our objectives for this study were to evaluate nest success and nest predator dynamics of sharp-tailed grouse (Tympanuchus phasianellus) in two study sites that represented areas of high and low energy development intensities in North Dakota. During the summers of 2012 and 2013, we monitored 163 grouse nests using radio telemetry. Of these, 90 nests also were monitored using miniature cameras to accurately determine nest fates and identify nest predators. We simultaneously conducted predator surveys using camera scent stations and occupancy modeling to estimate nest predator occurrence at each site. American badgers (Taxidea taxus) and striped skunks (Mephitis mephitis) were the primary nest predators, accounting for 56.7% of all video recorded nest depredations. Nests in our high intensity gas and oil area were 1.95 times more likely to succeed compared to our minimal intensity area. Camera monitored nests were 2.03 times more likely to succeed than non-camera monitored nests. Occupancy of mammalian nest predators was 6.9 times more likely in our study area of minimal gas and oil intensity compared to the high intensity area. Although only a correlative study, our results suggest energy development may alter the predator community, thereby increasing nest success for sharp-tailed grouse in areas of intense development, while adjacent areas may have increased predator occurrence and reduced nest success. Our study illustrates the potential influences of energy development on the nest predator-prey dynamics of sharp-tailed grouse in western North Dakota and the complexity of evaluating such impacts on wildlife.

Modelling highly deformable metal extrusion using SPH

NASA Astrophysics Data System (ADS)

Prakash, Mahesh; Cleary, Paul W.

2015-05-01

Computational modelling is often used to reduce trial extrusions through accurate defect prediction. Traditionally, metal extrusion is modelled using mesh based finite element methods. However, large plastic deformations can lead to heavy re-meshing and numerical diffusion. Here we use the mesh-less smoothed particle hydrodynamics method since it allows simulation of large deformations without re-meshing and the tracking of history dependent properties such as plastic strain making it suitable for defect prediction. The variation in plastic strain and deformation for aluminium alloy in a cylindrical 3D geometry with extrusion ratio and die angle is evaluated. The extrusion process is found to have three distinct phases consisting of an initial sharp rise in extrusion force, a steady phase requiring constant force and terminating in a sharp decline in force as metal is completely extruded. Deformation and plastic strain increased significantly with extrusion ratio but only moderately with die angle. Extrusion force increased by 150 % as the extrusion ratio increased from 2:1 to 4:1 but had only a marginal change with die angle. A low strain zone in the centre of the extruded product was found to be a function of extrusion ratio but was persistent and did not vary with die angle. Simulation of a complex 3D building industry component showed large variations in plastic strain along the length of the product at two scales. These were due to change in metal behaviour as extrusion progressed from phase 1 to phase 2. A stagnation zone at the back of the die was predicted that could lead to the "funnel" or "pipe" defect.

Curiosity Rover View of Alluring Martian Geology Ahead

NASA Image and Video Library

2015-08-05

A southward-looking panorama combining images from both cameras of the Mast Camera Mastcam instrument on NASA Curiosity Mars Rover shows diverse geological textures on Mount Sharp. A southward-looking panorama combining images from both cameras of the Mast Camera (Mastcam) instrument on NASA's Curiosity Mars Rover shows diverse geological textures on Mount Sharp. Three years after landing on Mars, the mission is investigating this layered mountain for evidence about changes in Martian environmental conditions, from an ancient time when conditions were favorable for microbial life to the much-drier present. Gravel and sand ripples fill the foreground, typical of terrains that Curiosity traversed to reach Mount Sharp from its landing site. Outcrops in the midfield are of two types: dust-covered, smooth bedrock that forms the base of the mountain, and sandstone ridges that shed boulders as they erode. Rounded buttes in the distance contain sulfate minerals, perhaps indicating a change in the availability of water when they formed. Some of the layering patterns on higher levels of Mount Sharp in the background are tilted at different angles than others, evidence of complicated relationships still to be deciphered. The scene spans from southeastward at left to southwestward at right. The component images were taken on April 10 and 11, 2015, the 952nd and 953rd Martian days (or sols) since the rover's landing on Mars on Aug. 6, 2012, UTC (Aug. 5, PDT). Images in the central part of the panorama are from Mastcam's right-eye camera, which is equipped with a 100-millimeter-focal-length telephoto lens. Images used in outer portions, including the most distant portions of the mountain in the scene, were taken with Mastcam's left-eye camera, using a wider-angle, 34-millimeter lens. http://photojournal.jpl.nasa.gov/catalog/PIA19803

Magnetic substorms and northward IMF turning

NASA Astrophysics Data System (ADS)

Troshichev, Oleg; Podorozhkina, Nataly

To determine the relation of the northward IMF turnings to substorm sudden onsets, we separated all events with sharp northward IMF turnings observed in years of solar maximum (1999-2002) and solar minimum (2007-2008). The events (N=261) have been classified in 5 groups in accordance with average magnetic activity in auroral zone (low, moderate or high levels of AL index) at unchanged or slightly changed PC index and with dynamics of PC (steady distinct growth or distinct decline) at arbitrary values of AL index. Statistical analysis of relationships between the IMF turning and changes of PC and AL indices has been fulfilled separately for each of 5 classes. Results of the analysis showed that, irrespective of geophysical conditions and solar activity epoch, the magnetic activity in the polar caps and in the auroral zone demonstrate no response to the sudden northward IMF turning, if the moment of northward turning is taken as a key date. Sharp increases of magnetic disturbance in the auroral zone are observed only under conditions of the growing PC index and statistically they are related to moment of the PC index exceeding the threshold level (~1.5 mV/m), not to northward turnings timed, as a rule, after the moment of sudden onset. Magnetic disturbances observed in these cases in the auroral zone (magnetic substorms) are guided by behavior of the PC index, like to ordinary magnetic substorms or substorms developed under conditions of the prolonged northward IMF impact on the magnetosphere. The evident inconsistency between the sharp IMF changes measured outside of the magnetosphere and behavior of the ground-based PC index, the latter determining the substorm development, provides an additional argument in favor of the PC index as a ground-based proxy of the solar wind energy that entered into magnetosphere.

3D Surface Reconstruction and Volume Calculation of Rills

NASA Astrophysics Data System (ADS)

Brings, Christine; Gronz, Oliver; Becker, Kerstin; Wirtz, Stefan; Seeger, Manuel; Ries, Johannes B.

2015-04-01

We use the low-cost, user-friendly photogrammetric Structure from Motion (SfM) technique, which is implemented in the Software VisualSfM, for 3D surface reconstruction and volume calculation of an 18 meter long rill in Luxembourg. The images were taken with a Canon HD video camera 1) before a natural rainfall event, 2) after a natural rainfall event and before a rill experiment and 3) after a rill experiment. Recording with a video camera results compared to a photo camera not only a huge time advantage, the method also guarantees more than adequately overlapping sharp images. For each model, approximately 8 minutes of video were taken. As SfM needs single images, we automatically selected the sharpest image from 15 frame intervals. The sharpness was estimated using a derivative-based metric. Then, VisualSfM detects feature points in each image, searches matching feature points in all image pairs, recovers the camera positions and finally by triangulation of camera positions and feature points the software reconstructs a point cloud of the rill surface. From the point cloud, 3D surface models (meshes) are created and via difference calculations of the pre and post models a visualization of the changes (erosion and accumulation areas) and quantification of erosion volumes are possible. The calculated volumes are presented in spatial units of the models and so real values must be converted via references. The outputs are three models at three different points in time. The results show that especially using images taken from suboptimal videos (bad lighting conditions, low contrast of the surface, too much in-motion unsharpness), the sharpness algorithm leads to much more matching features. Hence the point densities of the 3D models are increased and thereby clarify the calculations.

Analysis of reverse martensitic transformation of prehardened 16XCH steel

NASA Astrophysics Data System (ADS)

Muravyev, Vasily; Frolov, Alexey; Lonchakov, Sergey; Bakhmatov, Pavel

2015-10-01

In the paper the structural evolution of previously tempered 16XCH steel is investigated. The influence of temperature and time conditions of heating on temperature of austenization is revealed and the influence of structural changes on steel properties is defined. The analysis of the obtained results showed an increase of plasticity at the initial stage of reverse martensitic transformation and an increase of plasticity at increased durability. It is experimentally found that reverse transformation of packet and lath martensite into the initial phase (holding for a fraction of a second, temperature 400-450°C) leads to a sharp, more than 2-fold, reduction of strength and increase of plasticity. The effect of increased plasticity under reverse martensitic transformation conditions is observed. The structure of packet and lath martensite is more fine-grained in comparison with initial quenching; the durability and plasticity are much higher. Despite the derived results, the revealed effects of increased plasticity and strength require further exploration to increase the reliability of constructions made of low-alloyed steels.

Late Pleistocene shallow water sand transported to the slope at IODP Sites U1484 and U1485 off the north coast of Papua New Guinea: how, when and why?

NASA Astrophysics Data System (ADS)

Mountain, G. S.; Browning, J. V.; Bova, S. C.

2017-12-01

IODP Exp 363 drilled two sites on a gently seaward-dipping terrace 18 and 21 km north of Papua New Guinea, enabling the study of mechanisms that bring shallow water sediment to the deep sea. We expect past changes in sea level and precipitation / fluvial run-off dominated this record, but additional processes may have been important. We examined Hole U1484B (1031 m water depth; 223 m drilled; 99.8% recovered) and detected 339 sharp-based sand layers 0.5 cm or more thick. In contrast to the background hemipelagic nanno-bearing silty clay, sand layers are graded or massive turbidites containing detrital grains, shallow-water benthic foraminifera, shell fragments and/or wood. δ18O values of Globigerinoides ruber tied to the isotopic curve of Lisiecki and Raymo (2004) show the densest concentration of sand layers in the last 310 ka occurred during the cooling trend of MIS stage 6. Stage 2 contains significantly fewer discrete sand beds, even during the coldest part of the LGM. Other times of glacial intensification show a similarly modest correlation to peak sand deposition. Sand layers strongly correlate with high values of magnetic susceptibility (MS) measured on unsplit cores, and when mapped to the MIS time scale, MS increases match times of ice growth / falling sea level more consistently than does the density of sand layers. We attribute this to reworking of discrete sand layers by bioturbation, indicating the need for caution tying the absence of sharp-based sands to times of transgression or low precipitation / fluvial run-off. Packages of especially thick and closely-spaced sharp-based sands match seismic reflections at Site U1484. Tracing these reflections throughout the grid of hi-res MCS site survey profiles reveals the areal distribution and transport path of sand as well as a direct tie to similar sharp-based sands in the more distal Hole U1485A (1145 m water depth; 301 m drilled; 103.8% recovered.) The distribution of sands through time might be influenced by sea level and/or precipitation, in which case they should exhibit orbital cyclicity and patterns in provenance. Alternatively, some may be turbidites that originated on the upper slope due to non-periodic earthquakes along this active plate boundary; inferences based on the age and provenance of sands at both sites will evaluate this possibility.

ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, HVLP COATING EQUIPMENT, SHARPE MANUFACTURING COMPANY PLATINUM 2012 HVLP SPRAY GUN

EPA Science Inventory

This report presents the results of the verification test of the Sharpe Platinum 2013 high-volume, low-pressure gravity-feed spray gun, hereafter referred to as the Sharpe Platinum, which is designed for use in automotive refinishing. The test coating chosen by Sharpe Manufacturi...

3D near-surface soil response from H/V ambient-noise ratios

USGS Publications Warehouse

Wollery, E.W.; Street, R.

2002-01-01

The applicability of the horizontal-to-vertical (H/V) ambient-noise spectral ratio for characterizing earthquake site effects caused by nearsurface topography and velocity structures was evaluated at sites underlain by thick (i.e. >100 m) sediment deposits near the southern-end of the New Madrid seismic zone in the central United States. Three-component ambient-noise and velocity models derived from seismic (shearwave) refraction/reflection surveys showed that a relatively horizontal, sharp shear-wave velocity interface in the soil column resulted in an H/V spectral ratio with a single well-defined peak. Observations at sites with more than one sharp shear-wave velocity contrast and horizontally arranged soil layers resulted in at least two well-defined H/V spectral ratio peaks. Furthermore, at sites where there were sharp shear-wave velocity contrasts in nonhorizontal, near-surface soil layers, the H/V spectra exhibited a broad-bandwidth, relatively low amplitude signal instead of a single well-defined peak. ?? 2002 Elsevier Science Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fedorova, T.A.; Babarin, P.M.

A sharp drop of uric acid in the urine of irradiated rats begins on the second day afier exposure, and a considerable increase of allantoin ( approximates 26%) was observed the next day sfter the exposure. (R.V.J.)

Rheology and tribology of lubricants with polymeric viscosity modifiers

NASA Astrophysics Data System (ADS)

Babak, LotfizadehDehkordi

Elastohydrodynamic lubrication (EHL) theory has been used to model the lubrication state of antifriction machine elements, where initial viscosity and pressure viscosity coefficients are essential parameters in film thickness modeling. Since the pressures of lubricants in the contact zone can be very high, it is important to know the rheological properties of lubricants in these pressure and temperature regimes. The characteristics of viscosity behavior as a function of pressure are also essential for a universal definition of the pressure viscosity coefficient in order to estimate film thickness in an EHL regime. In this study, viscosities and pressure-viscosity coefficients of ten commercial engine and gear oils and seventeen laboratory-produced oil/polymer viscosity modifiers (VM) additives are measured up to 1.3 GPa at 40, 75 and 100 °C. For the first time, a sharp increase in the viscosity and piezoviscous factor is observed in both mineral-based and synthetic-based oils with different VMs. Analysis of the experimental results indicates that sharp increase in viscosity observed in these experiments are believed to arise from physical changes in the VMs, that is liquid-solid phase transition. Evidence is offered that polymer properties such as molecular weight, concentration and structure influence the onset of the phase transitions. A modified Yasutomi model, which normally describes the pressure dependence of the viscosity of lubricants very well, fails to predict the viscosity of the specimens above the onset of sharp increase in viscosity. A design of experiment (DOE) analysis using Design-Expert software indicates that pressure and temperature are the most critical parameters in the viscosity variation. Tribological tests demonstrate that wear in the contact, zone occurs at temperatures and stresses that coincides with the VM phase transitions in both commercial and laboratory synthesized oil/VMs. Tribological results also indicate that the onset of the sharp increase in viscosity can have significant and unanticipated consequences on the elastohydrodynamic contact and can adversely affect EHL theory. The onset of the steep rise in viscosity may also affect the torque and power losses in a mechanical system. Hence, this previously unknown behavior of the lubricant with VMs should be seriously considered in the application of lubricant in mechanical system.

Use of hub cutters and the volume of sharp waste and occurrence of needle-stick injuries during 2011 mass immunization campaigns against yellow fever in Ghana: a cohort study.

PubMed

Agbenu, E; Chartier, Y; Eleeza, J; Antwi-Agyei, K O; Diamenu, S; Ronveaux, O; Perea, W

2014-01-01

Current WHO best infection control practices for injections do not address the use of hub cutters due to insufficient evidence on safety and efficacy. To assess the impact of the use of hub cutters on 1) the frequency of needle-stick injuries (NSIs) and other blood exposures among workers and 2) the volume of sharps waste in a mass vaccination campaign setting. During yellow fever vaccination in Ghana, we conducted a cohort study on the use of hub cutters. We compared two groups---one group using hub cutters and a control group---for the occurrences of NSIs and the volume of sharp waste produced. In the control arm, vaccinators used 284 482 syringes in 825 vaccination sessions. In the group using hub cutter, vaccinators used 397 079 syringes in 1599 sessions. Among vaccinators, the rate of NSI was not significantly (p=0.14) different between the hub cutter users (0.15/10 000 syringes) and the control group (0.04/10 000). Factors such as workload, lack of organization and pressure seemed to have influence the occurrence of NSIs. With all the limitations of the work, the volume of sharp waste per 10 000 syringes was 0.24 m(3) in the hub cutter users and 0.41 m(3) in the control group---a reduction of 41.2%. Vaccinators found hub cutters easy to use and safe. Use of hub cutter was not associated with increased duration of work. The use of hub cutters did not increase the risk of NSIs. More training is needed to facilitate its implementation in mass campaign setting.

[Disease burden caused by violence in the Chinese population, in 1990 and 2013].

PubMed

Yang, L; Gao, X; Jin, Y; Ye, P P; Er, Y L; Deng, X; Wang, Y; Duan, L L

2017-10-10

Objective: To analyze the disease burden of violence in the Chinese population, in 1990 and 2013. Methods: Indicators including mortality rate, years of life lost due to premature mortality (YLL), years lived with disability (YLD), and disability-adjusted of life years (DALY) related to violence, were extracted from the Global Burden of Disease 2013 and used to describe the burden of disease caused by violence in the Chinese population. Data related to corresponding parameters on disease burden of violence in 1990 and 2013 were described. Results: In 2013, a total of 20 500 people died of violent events, with the death rate as 1.44 per 100 000, in China. DALY caused by violence was 1.08 million person years in 2013. DALY caused by sharp violence was 0.47 million person years, with 0.09 million person years lost due to firearm violence. Disease burden caused by violence appeared higher in males than in females. When comparing with data from the 1990s, reductions were seen by 67.35 % on the standardized death rate of violence, by 68.07 % on the DALY attributable to violence, and by 70.47 % on the standardized DALY rate attributable to violence, respectively, in 2013. Disease burden of violence among young adults and elderly was among the highest. When comparing with data from the 1990, DALY in 2013 decreased among all the age groups except for the 70-year-old showed an increase of 9.36 % . The standardized DALY rate in 2013 showed a declining trend in all the age groups, mostly in the 0-4-year-old group. The standardized DALY rates caused by sharp violence or firearm decreased by75.11 % and 83.20 % in the 0-4-year-old group. Conclusion: In recent years, the disease burden caused by violence showed a decreasing trend but appeared higher in males however with the increase of DALY in the elder population.

Detection of a Sharp Structural Boundary in Lowermost Mantle Beneath Alaska by Core Phase PKPbc-df Differential Travel Times - Observation from the Anomalous South Sandwich Islands to Alaska Path

NASA Astrophysics Data System (ADS)

Xin, L.; Kawakatsu, H.; Takeuchi, N.

2017-12-01

Differential travel time residuals of PKPbc and PKPdf for the path from South Sandwich Islands (SSI) to Alaska are usually used to constrain anisotropy of the western hemisphere of the Earth's inner-core. For this polar path, it has been found that PKPbc-df differential residuals are generally anomalously larger than data that sample other regions, and also show strong lateral variation. Due to sparse distribution of seismic stations in Alaska in early times, previous researches have been unable to propose a good model to explain this particular data set. Using data recorded by the current dense stations in Alaska for SSI earthquakes, we reexamine the anomalous behavior of core phase PKPbc-df differential travel times and try to explain the origin. The data sample the inner-core for the polar paths, as well as the lowermost mantle beneath Alaska. Our major observations are: (1) fractional travel time residuals of PKPbc-df increase rapidly within 2° (up to 1%). (2) A clear shift of the residual pattern could be seen for earthquakes with different locations. (3) The residual shows systematic lateral variation: at northern part, no steep increase of residual can be seen. A sharp lateral structural boundary with a P-wave velocity contrast of about 3% at lowermost mantle beneath East Alaska is invoked to explain the steep increase of the observed residuals. By combining the effects of a uniformly anisotropic inner-core and the heterogeneity, the observed residual patterns could be well reproduced. This high velocity anomaly might be related with an ancient subducted slab. Lateral variation of the PKPbc-df residuals suggests that the heterogeneity layer is not laterally continuous and may terminate beneath Northeastern Alaska. We also conclude that core phases may be strongly affected by heterogeneities at lowermost mantle, and should be carefully treated if they are used to infer the inner-core structure.

Molecular cloning, characterization and expression analysis of PPAR gamma in the orange-spotted grouper (Epinephelus coioides) after the Vibrio alginolyticus challenge.

PubMed

Luo, Shengwei; Huang, Youhua; Xie, Fuxing; Huang, Xiaohong; Liu, Yuan; Wang, Weina; Qin, Qiwei

2015-04-01

PPAR gamma was a key nuclear receptor, playing an important role in the immune defense and the anti-inflammatory mechanism. In this study, the full-length PPAR gamma (EcPPAR gamma) was obtained, containing a 5'UTR of 133 bp, an ORF of 1602 bp and a 3'UTR of 26 bp besides the poly (A) tail. The EcPPAR gamma gene encoded a protein of 533 amino acids with an estimated molecular mass of 60.02 KDa and a predicted isoelectric point (pI) of 6.26. The deduced amino acid sequence showed that EcPPAR gamma consisted of the conserved residues and the domains known to be critical for the PPAR gamma function. The quantitative real-time PCR analysis revealed that EcPPAR gamma transcript was expressed in all the examined tissue, while the strong expression was observed in intestine, followed by the expression in liver, gill, spleen heart, kidney and muscle. Vibrio challenge could stimulate the inflammatory response in grouper and induce a sharp increase of pro-inflammatory cytokines expression, lipid peroxidation and DNA damage, while the up-regulation of vibrio-induced inflammation could also increase the non-specific immune defense. The groupers challenged with Vibrio alginolyticus showed a sharp increase of EcPPAR gamma transcript in immune tissues. Subcellular localization analysis revealed that EcPPAR gamma was distributed in the nucleus. Furthermore, overexpression of EcPPAR gamma could down-regulated the expression of IL1b, IL6, TNF1 and TNF2. In addition, the administration of PPAR gamma antagonist, GW9662, could up-regulate the expression of pro-inflammatory genes, including IL1b, IL6, TNF1 and TNF2. Together, these results indicated that EcPPAR gamma serving as a negative regulator of pro-inflammatory cytokines may play an important role in the immune defense against vibrio-induced inflammation in grouper. Copyright © 2015 Elsevier Ltd. All rights reserved.

Electrochemical and Passive Behaviors of Pure Copper Fabricated by Accumulative Roll-Bonding (ARB) Process

NASA Astrophysics Data System (ADS)

Imantalab, O.; Fattah-alhosseini, A.

2015-07-01

In the present work, electrochemical and passive behaviors of pure copper fabricated by accumulative roll-bonding (ARB) process in 0.01 M borax solution (pH = 9.1) have been studied. Before any electrochemical measurements, evaluation of microstructure was obtained by Vickers microhardness, x-ray diffraction (XRD), and transmission electron microscopy. The results of microhardness tests revealed that microhardness values increased with the increasing number of ARB cycles. Also a sharp increase was seen in microhardness after the first ARB cycle, whereas mediocre additional increases were observed afterward up to the seven cycles. Moreover, XRD patterns showed that the mean crystallite size values decrease with the increasing number of ARB cycles. To investigate the electrochemical and passive behaviors of the samples, the potentiodynamic polarization, Mott-Schottky analysis and electrochemical impedance spectroscopy (EIS) were carried out. Polarization plots revealed that as a result of ARB, the corrosion behavior of the specimens improves compared with the annealed pure copper. Also, the Mott-Schottky analysis and EIS measurements showed that the increasing number of ARB cycles offer better conditions for forming the passive films with higher protection behavior, due to the growth of less-defective films.

On the non-existence of a sharp cooling break in gamma-ray burst afterglow spectra

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uhm, Z. Lucas; Zhang, Bing, E-mail: uhm@physics.unlv.edu, E-mail: zhang@physics.unlv.edu

Although the widely used analytical afterglow model of gamma-ray bursts (GRBs) predicts a sharp cooling break ν {sub c} in its afterglow spectrum, the GRB observations so far rarely show clear evidence for a cooling break in their spectra or a corresponding temporal break in their light curves. Employing a Lagrangian description of the blast wave, we conduct a sophisticated calculation of the afterglow emission. We precisely follow the cooling history of non-thermal electrons accelerated into each Lagrangian shell. We show that a detailed calculation of afterglow spectra does not in fact give rise to a sharp cooling break atmore » ν {sub c}. Instead, it displays a very mild and smooth transition, which occurs gradually over a few orders of magnitude in energy or frequency. The main source of this slow transition is that different mini shells have different evolutionary histories of the comoving magnetic field strength B, so that deriving the current value of ν {sub c} of each mini shell requires an integration of its cooling rate over the time elapsed since its creation. We present the time evolution of optical and X-ray spectral indices to demonstrate the slow transition of spectral regimes and discuss the implications of our result in interpreting GRB afterglow data.« less

77 FR 52061 - Notice of Proposed Exemption Involving Sharp HealthCare Located in San Diego, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-28

...This document contains a notice of pendency (the Notice) before the Department of Labor (the Department) of a proposed individual exemption from certain prohibited transaction restrictions of the Employee Retirement Income Security Act of 1974 (the Act or ERISA). The transactions involve the Sharp HealthCare Health and Dental Plan (the Plan). The proposed exemption, if granted, would affect the Plan, its participants and beneficiaries, Sharp Healthcare (Sharp), and the Sharp Health Plan (the HMO).

Receptivity of Hypersonic Boundary Layers to Acoustic and Vortical Disturbances (Invited)

NASA Technical Reports Server (NTRS)

Balakumar, P.

2015-01-01

Boundary-layer receptivity to two-dimensional acoustic and vortical disturbances for hypersonic flows over two-dimensional and axi-symmetric geometries were numerically investigated. The role of bluntness, wall cooling, and pressure gradients on the receptivity and stability were analyzed and compared with the sharp nose cases. It was found that for flows over sharp nose geometries in adiabatic wall conditions the instability waves are generated in the leading-edge region and that the boundary layer is much more receptive to slow acoustic waves as compared to the fast waves. The computations confirmed the stabilizing effect of nose bluntness and the role of the entropy layer in the delay of boundary layer transition. The receptivity coefficients in flows over blunt bodies are orders of magnitude smaller than that for the sharp cone cases. Wall cooling stabilizes the first mode strongly and destabilizes the second mode. However, the receptivity coefficients are also much smaller compared to the adiabatic case. The adverse pressure gradients increased the unstable second mode regions.

Clinical laboratory waste management in Shiraz, Iran.

PubMed

Askarian, Mehrdad; Motazedian, Nasrin; Palenik, Charles John

2012-06-01

Clinical laboratories are significant generators of infectious waste, including microbiological materials, contaminated sharps, and pathologic wastes such as blood specimens and blood products. Most waste produced in laboratories can be disposed of in the general solid waste stream. However, improper management of infectious waste, including mixing general wastes with infectious wastes and improper handling or storage, could lead to disease transmission. The aim of this study was to assess waste management processes used at clinical laboratories in Shiraz, Iran. One hundred and nine clinical laboratories participated In this cross sectional study, Data collection was by questionnaire and direct observation. Of the total amount of waste generated, 52% (by weight) was noninfectious domestic waste, 43% was non-sharps infectious waste and 5% consisted of sharps. There was no significant relationship between laboratory staff or manager education and the score for quality of waste collection and disposal at clinical laboratories. Improvements in infectious waste management processes should involve clearer, more uniformly accepted definitions of infectious waste and increased staff training.

Implementing AORN recommended practices for sharps safety.

PubMed

Ford, Donna A

2014-01-01

Prevention of percutaneous sharps injuries in perioperative settings remains a challenge. Occupational transmission of bloodborne pathogens, not only from patients to health care providers but also from health care providers to patients, is a significant concern. Legislation and position statements geared toward ensuring the safety of patients and health care workers have not resulted in significantly reduced sharps injuries in perioperative settings. Awareness and understanding of the types of percutaneous injuries that occur in perioperative settings is fundamental to developing an effective sharps injury prevention program. The AORN "Recommended practices for sharps safety" clearly delineates evidence-based recommendations for sharps injury prevention. Perioperative RNs can lead efforts to change practice for the safety of patients and perioperative team members by promoting the elimination of sharps hazards; the use of engineering, work practice, and administrative controls; and the proper use of personal protective equipment, including double gloving. Copyright © 2014 AORN, Inc. Published by Elsevier Inc. All rights reserved.

The SHARP Program: Giving Kids Chances to Excel

ERIC Educational Resources Information Center

Kenney, Rich

2007-01-01

In this article, the author describes the Sports, Habilitation, and Recreation Program (SHARP), a program of the Foundation for Blind Children in Phoenix, Arizona. The SHARP program aims to help children, who have visual impairments, achieve goals, develop independence, and make friends. One of the unique features of the SHARP program is that it…

Revealing stiffening and brittling of chronic myelogenous leukemia hematopoietic primary cells through their temporal response to shear stress.

PubMed

Laperrousaz, B; Berguiga, L; Nicolini, F E; Martinez-Torres, C; Arneodo, A; Satta, V Maguer; Argoul, F

2016-06-02

Cancer cell transformation is often accompanied by a modification of their viscoelastic properties. When capturing the stress-to-strain response of primary chronic myelogenous leukemia (CML) cells, from two data sets of CD34+ hematopoietic cells isolated from healthy and leukemic bone marrows, we show that the mean shear relaxation modulus increases upon cancer transformation. This stiffening of the cells comes along with local rupture events, detected as reinforced sharp local maxima of this modulus, suggesting that these cancer cells respond to a local mechanical stress by a cascade of local brittle failure events.

Revealing stiffening and brittling of chronic myelogenous leukemia hematopoietic primary cells through their temporal response to shear stress

NASA Astrophysics Data System (ADS)

Laperrousaz, B.; Berguiga, L.; Nicolini, F. E.; Martinez-Torres, C.; Arneodo, A.; Maguer Satta, V.; Argoul, F.

2016-06-01

Cancer cell transformation is often accompanied by a modification of their viscoelastic properties. When capturing the stress-to-strain response of primary chronic myelogenous leukemia (CML) cells, from two data sets of CD34+ hematopoietic cells isolated from healthy and leukemic bone marrows, we show that the mean shear relaxation modulus increases upon cancer transformation. This stiffening of the cells comes along with local rupture events, detected as reinforced sharp local maxima of this modulus, suggesting that these cancer cells respond to a local mechanical stress by a cascade of local brittle failure events.

Tricritical spiral vortex instability in cross-slot flow.

PubMed

Haward, Simon J; Poole, Robert J; Alves, Manuel A; Oliveira, Paulo J; Goldenfeld, Nigel; Shen, Amy Q

2016-03-01

We examine fluid flow through cross-slot devices with various depth to width ratios α. At low Reynolds number, Re, flow is symmetric and a sharp boundary exists between the two incoming fluid streams. Above an α-dependent critical value, Re(c)(α), a steady symmetry-breaking bifurcation occurs and a spiral vortex structure develops. Order parameters characterizing the instability grow according to a sixth-order Landau potential, and show a progression from second- to first-order transitions as α increases beyond a tricritical value of α ≈ 0.55. Flow simulations indicate the instability is driven by vortex stretching at the stagnation point.

A multi-spectroscopic and molecular docking approach to investigate the interaction of antiviral drug oseltamivir with ct-DNA.

PubMed

Moghadam, Neda Hosseinpour; Salehzadeh, Sadegh; Shahabadi, Nahid; Golbedaghi, Reza

2017-07-03

The possible interaction between the antiviral drug oseltamivir and calf thymus DNA at physiological pH was studied by spectrophotometry, competitive spectrofluorimetry, differential pulse voltammogram (DPV), circular dichroism spectroscopy (CD), viscosity measurements, salt effect, and computational studies. Intercalation of oseltamivir between the base pairs of DNA was shown by a sharp increase in specific viscosity of DNA and a decrease of the peak current and a positive shift in differential pulse voltammogram. Competitive fluorescence experiments were performed using neutral red (NR) as a probe for the intercalation binding mode. The studies showed that oseltamivir is able to release the NR.

Changes in the Distribution of American Family Incomes, 1947 to 1984

NASA Astrophysics Data System (ADS)

Levy, Frank

1987-05-01

The American family income distribution now lies at the center of several controversies. Some observers argue that the American middle class is vanishing, but U.S. census income statistics show income inequality has not changed appreciably since 1947. A second controversy involves whether average living standards have risen or fallen since the major oil price increase of 1973-74. These controversies can be partially resolved by understanding the sharp slowdown in the growth of workers' wages which occurred after 1973 and the demographic trends which kept per capita living standards rising despite stagnant wages, including more working women and low birthrates.

Quasiparticle mass enhancement close to the quantum critical point in BaFe2(As(1-x)P(x))2.

PubMed

Walmsley, P; Putzke, C; Malone, L; Guillamón, I; Vignolles, D; Proust, C; Badoux, S; Coldea, A I; Watson, M D; Kasahara, S; Mizukami, Y; Shibauchi, T; Matsuda, Y; Carrington, A

2013-06-21

We report a combined study of the specific heat and de Haas-van Alphen effect in the iron-pnictide superconductor BaFe2(As(1-x)P(x))2. Our data when combined with results for the magnetic penetration depth give compelling evidence for the existence of a quantum critical point close to x=0.30 which affects the majority of the Fermi surface by enhancing the quasiparticle mass. The results show that the sharp peak in the inverse superfluid density seen in this system results from a strong increase in the quasiparticle mass at the quantum critical point.

Background field removal technique using regularization enabled sophisticated harmonic artifact reduction for phase data with varying kernel sizes.

PubMed

Kan, Hirohito; Kasai, Harumasa; Arai, Nobuyuki; Kunitomo, Hiroshi; Hirose, Yasujiro; Shibamoto, Yuta

2016-09-01

An effective background field removal technique is desired for more accurate quantitative susceptibility mapping (QSM) prior to dipole inversion. The aim of this study was to evaluate the accuracy of regularization enabled sophisticated harmonic artifact reduction for phase data with varying spherical kernel sizes (REV-SHARP) method using a three-dimensional head phantom and human brain data. The proposed REV-SHARP method used the spherical mean value operation and Tikhonov regularization in the deconvolution process, with varying 2-14mm kernel sizes. The kernel sizes were gradually reduced, similar to the SHARP with varying spherical kernel (VSHARP) method. We determined the relative errors and relationships between the true local field and estimated local field in REV-SHARP, VSHARP, projection onto dipole fields (PDF), and regularization enabled SHARP (RESHARP). Human experiment was also conducted using REV-SHARP, VSHARP, PDF, and RESHARP. The relative errors in the numerical phantom study were 0.386, 0.448, 0.838, and 0.452 for REV-SHARP, VSHARP, PDF, and RESHARP. REV-SHARP result exhibited the highest correlation between the true local field and estimated local field. The linear regression slopes were 1.005, 1.124, 0.988, and 0.536 for REV-SHARP, VSHARP, PDF, and RESHARP in regions of interest on the three-dimensional head phantom. In human experiments, no obvious errors due to artifacts were present in REV-SHARP. The proposed REV-SHARP is a new method combined with variable spherical kernel size and Tikhonov regularization. This technique might make it possible to be more accurate backgroud field removal and help to achive better accuracy of QSM. Copyright © 2016 Elsevier Inc. All rights reserved.

Excess vitamin intake: An unrecognized risk factor for obesity.

PubMed

Zhou, Shi-Sheng; Zhou, Yiming

2014-02-15

Over the past few decades, food fortification and infant formula supplementation with high levels of vitamins have led to a sharp increase in vitamin intake among infants, children and adults. This is followed by a sharp increase in the prevalence of obesity and related diseases, with significant disparities among countries and different groups within a country. It has long been known that B vitamins at doses below their toxicity threshold strongly promote body fat gain. Studies have demonstrated that formulas, which have very high levels of vitamins, significantly promote infant weight gain, especially fat mass gain, a known risk factor for children developing obesity. Furthermore, ecological studies have shown that increased B vitamin consumption is strongly correlated with the prevalence of obesity and diabetes. We therefore hypothesize that excess vitamins may play a causal role in the increased prevalence of obesity. This review will discuss: (1) the causes of increased vitamin intake; (2) the non-monotonic effect of excess vitamin intake on weight and fat gain; and (3) the role of vitamin fortification in obesity disparities among countries and different groups within a country.

Excess vitamin intake: An unrecognized risk factor for obesity

PubMed Central

Zhou, Shi-Sheng; Zhou, Yiming

2014-01-01

Over the past few decades, food fortification and infant formula supplementation with high levels of vitamins have led to a sharp increase in vitamin intake among infants, children and adults. This is followed by a sharp increase in the prevalence of obesity and related diseases, with significant disparities among countries and different groups within a country. It has long been known that B vitamins at doses below their toxicity threshold strongly promote body fat gain. Studies have demonstrated that formulas, which have very high levels of vitamins, significantly promote infant weight gain, especially fat mass gain, a known risk factor for children developing obesity. Furthermore, ecological studies have shown that increased B vitamin consumption is strongly correlated with the prevalence of obesity and diabetes. We therefore hypothesize that excess vitamins may play a causal role in the increased prevalence of obesity. This review will discuss: (1) the causes of increased vitamin intake; (2) the non-monotonic effect of excess vitamin intake on weight and fat gain; and (3) the role of vitamin fortification in obesity disparities among countries and different groups within a country. PMID:24567797

Single ingestion of soy β-conglycinin induces increased postprandial circulating FGF21 levels exerting beneficial health effects.

PubMed

Hashidume, Tsutomu; Kato, Asuka; Tanaka, Tomohiro; Miyoshi, Shoko; Itoh, Nobuyuki; Nakata, Rieko; Inoue, Hiroyasu; Oikawa, Akira; Nakai, Yuji; Shimizu, Makoto; Inoue, Jun; Sato, Ryuichiro

2016-06-17

Soy protein β-conglycinin has serum lipid-lowering and anti-obesity effects. We showed that single ingestion of β-conglycinin after fasting alters gene expression in mouse liver. A sharp increase in fibroblast growth factor 21 (FGF21) gene expression, which is depressed by normal feeding, resulted in increased postprandial circulating FGF21 levels along with a significant decrease in adipose tissue weights. Most increases in gene expressions, including FGF21, were targets for the activating transcription factor 4 (ATF4), but not for peroxisome proliferator-activated receptor α. Overexpression of a dominant-negative form of ATF4 significantly reduced β-conglycinin-induced increases in hepatic FGF21 gene expression. In FGF21-deficient mice, β-conglycinin effects were partially abolished. Methionine supplementation to the diet or primary hepatocyte culture medium demonstrated its importance for activating liver or hepatocyte ATF4-FGF21 signaling. Thus, dietary β-conglycinin intake can impact hepatic and systemic metabolism by increasing the postprandial circulating FGF21 levels.

Holographic thermalization and generalized Vaidya-AdS solutions in massive gravity

NASA Astrophysics Data System (ADS)

Hu, Ya-Peng; Zeng, Xiao-Xiong; Zhang, Hai-Qing

2017-02-01

We investigate the effect of massive graviton on the holographic thermalization process. Before doing this, we first find out the generalized Vaidya-AdS solutions in the de Rham-Gabadadze-Tolley (dRGT) massive gravity by directly solving the gravitational equations. Then, we study the thermodynamics of these Vaidya-AdS solutions by using the Misner-Sharp energy and unified first law, which also shows that the massive gravity is in a thermodynamic equilibrium state. Moreover, we adopt the two-point correlation function at equal time to explore the thermalization process in the dual field theory, and to see how the graviton mass parameter affects this process from the viewpoint of AdS/CFT correspondence. Our results show that the graviton mass parameter will increase the holographic thermalization process.

Thermal hysteresis of the phase-transition temperature of single-crystal GdB6

NASA Astrophysics Data System (ADS)

Reiffers, M.; Ebek, J.; Antavá, E.; Pristá, G.; Kunii, S.

2006-01-01

The phase transition of a single-crystal sample of GdB6, oriented along the 111 axis using the temperature dependence of electrical resistivity (T ), susceptibility (T ) and heat capacity C (T ) under an applied magnetic field was studied. ρ (T ) has shown 2 anomalies - a sharp drop at T N1 = 15.4 K and a small maximum at T N2 = 9.1 K with thermal hysteresis effect. χ (T ) shows the anomalies at both transition temperatures. C (T ) shows similar thermal hysteresis effect at T N2. The small maximum at T N2 decreases its position to lower temperatures with increasing magnetic field. The peak at T N1 is practically unaffected by an applied magnetic field up to 9 T.

Reward Processing And Risk For Depression Across Development

PubMed Central

Luking, Katherine R; Pagliaccio, David; Luby, Joan L; Barch, Deanna M

2016-01-01

Striatal response to reward has been of great interest in the typical development and psychopathology literatures. These parallel lines of inquiry demonstrate that while typically developing adolescents show robust striatal response to reward, adolescents with major depressive disorder (MDD) or those at high-risk for MDD show blunted response to reward. Understanding how these findings intersect is critical for the development and application of early preventative interventions in at-risk children, ideally before the sharp increase in the rate of MDD onset that occurs in adolescence. Robust findings relating blunted striatal response to reward and MDD-risk are reviewed and situated within a normative developmental context. We highlight the need for future studies investigating longitudinal development, specificity to MDD, and roles of potential moderators and mediators. PMID:27131776

Fabrication and characterization of a piezoelectric energy harvester with clamped-clamped beams

NASA Astrophysics Data System (ADS)

Cui, Yan; Yu, Menglin; Gao, Shiqiao; Kong, Xiangxin; Gu, Wang; Zhang, Ran; Liu, Bowen

2018-05-01

This work presents a piezoelectric energy harvester with clamped-clamped beams, and it is fabricated with MEMS process. When excited by sinusoidal vibration, the energy harvester has a sharp jumping down phenomenon and the measured frequency responses of the clamped-clamped beams structure show a larger bandwidth which is about 56Hz, more efficient than that with cantilever beams. When the exciting acceleration ac is 12m/s2, the energy harvester achieves to a maximum open-circuit voltage of 94mV on one beam. The load voltage is proportional to the load resistance, and it increased with the increase of load resistance. Connected four beams in series, the output power reaches the maximum value of 730 nW and the optimal load is 15KΩ to one beam.

Metastability of the midgap level EL 2 in GaAs - Relationship with the As antisite defect

NASA Technical Reports Server (NTRS)

Skowronski, M.; Lagowski, J.; Gatos, H. C.

1985-01-01

It is found that the rate of the photoinduced transition of the GaAs midgap level EL 2 to its metastable state increases as its occupation increases. High-resolution optical spectra of this transition exhibit a sharp peak very similar to the no-phonon line of the intracenter absorption of the As antisite defect. These findings show that the transition to the metastable state is initiated from the ground state 1A1, and it is finalized via the excited state 1T2 of the neutral As antisite defect. They thus provide a new basis for the critical assessment of the EL 2 metastability models and further confirmation of the association of EL 2 with the isolated As antisite defect.

Dissolution of topological Fermi arcs in a dirty Weyl semimetal

NASA Astrophysics Data System (ADS)

Slager, Robert-Jan; Juričić, Vladimir; Roy, Bitan

2017-11-01

Weyl semimetals (WSMs) have recently attracted a great deal of attention as they provide a condensed matter realization of chiral anomaly, feature topologically protected Fermi arc surface states, and sustain sharp chiral Weyl quasiparticles up to a critical disorder at which a continuous quantum phase transition (QPT) drives the system into a metallic phase. We here numerically demonstrate that with increasing strength of disorder, the Fermi arc gradually loses its sharpness, and close to the WSM-metal QPT it completely dissolves into the metallic bath of the bulk. The predicted topological nature of the WSM-metal QPT and the resulting bulk-boundary correspondence across this transition can be directly observed in angle-resolved photoemission spectroscopy (ARPES) and Fourier transformed scanning tunneling microscopy (STM) measurements by following the continuous deformation of the Fermi arcs with increasing disorder in recently discovered Weyl materials.

Environmental Exposures and Children's Health Challenges

ERIC Educational Resources Information Center

Landrigan, Philip J.

2005-01-01

The author looks at the sharp increase in a number of childhood disorders--including asthma, certain cancers, and learning/behavioral disabilities--and the role environmental toxins may play in this increase. He describes the need to train many more health professionals in prenatal and children's environmental health and the national network of…

Can the Internet Be Saved?

ERIC Educational Resources Information Center

Fischman, Josh

2007-01-01

The Internet has great difficulty coping with the sharp increase in mobile devices like cellphones and laptops, and handling bandwidth-hungry traffic such as video, now demanded by an increasing number of users. According to Ellen W. Zegura, chairwoman of computer sciences at the Georgia Institute of Technology, the Internet is like a big…

Sharp Injury and Exposure to Blood and Body Fluids among Health Care Workers in Health Care Centers of Eastern Ethiopia.

PubMed

Alemayehu, T; Worku, A; Assefa, N

2016-07-01

Health care workers are facing certain occupational hazards because of sharp injury and exposure to human blood and body fluids as a result of handling wastes. Though much attention is paid for the protection of these workers, the number of exposures and injuries do not show a sign of decline from time to time. To examine the occurrence of sharp injury and exposure to blood and body fluids in health care workers in health care centers in Ethiopia. In a case-control study, a randomly selected sample of 65 health facilities with 391 cases and 429 controls were studied. Data were collected through a self-administered questionnaire. Detailed analysis of exposure among the health care workers was done by logistic regression analysis with generalized estimating equations model to control correlation effects of responses within the cluster of health facilities. The number of health care workers who got sharp injury was 217 (26.5%). 296 (36.1%) had exposure to blood and body fluids. Working at Harari region (adjusted OR 0.44, 95% CI 0.26 to 0.75) and East Hararghea (adjusted OR 0.61, 95% CI 0.40 to 0.94), being male (adjusted OR 0.56, 95% CI 0.44 to 0.91), and a being nurse (adjusted OR 0.188, 95% CI 0.06 to 0.63) were independent risk factors of the exposure. Regardless of the anticipated low self-reporting for exposure status, the number of health care workers reported having sharp injury and exposure to blood and body fluids was high. Such high exposures indicate that health care workers are at high risk of acquiring blood-borne viral infections such as hepatitis B, hepatitis C, and HIV.

SHARP: Spacecraft Health Automated Reasoning Prototype

NASA Technical Reports Server (NTRS)

Atkinson, David J.

1991-01-01

The planetary spacecraft mission OPS as applied to SHARP is studied. Knowledge systems involved in this study are detailed. SHARP development task and Voyager telecom link analysis were examined. It was concluded that artificial intelligence has a proven capability to deliver useful functions in a real time space flight operations environment. SHARP has precipitated major change in acceptance of automation at JPL. The potential payoff from automation using AI is substantial. SHARP, and other AI technology is being transferred into systems in development including mission operations automation, science data systems, and infrastructure applications.

The effect of pumping noise on the characteristics of a single-stage parametric amplifier

NASA Astrophysics Data System (ADS)

Medvedev, S. Iu.; Muzychuk, O. V.

1983-10-01

An analysis is made of the operation of a single-stage parametric amplifier based on a varactor with a sharp transition. Analytical expressions are obtained for the statistical moments of the output signal, the signal-noise ratio, and other characteristics in the case when the output signal and the pump are a mixture of harmonic oscillation and Gaussian noise. It is shown that, when a noise component is present in the pump, an increase of its harmonic component to values close to the threshold leads to a sharp decrease in the signal-noise ratio at the amplifier output.

An analytical formalism accounting for clouds and other `surfaces' for exoplanet transmission spectroscopy

NASA Astrophysics Data System (ADS)

Bétrémieux, Yan; Swain, Mark R.

2017-05-01

Although the formalism of Lecavelier des Etangs et al. is extremely useful to understand what shapes transmission spectra of exoplanets, it does not include the effects of a sharp change in flux with altitude generally associated with surfaces and optically thick clouds. Recent advances in understanding the effects of refraction in exoplanet transmission spectra have, however, demonstrated that even clear thick atmospheres have such a sharp change in flux due to a refractive boundary. We derive a more widely applicable analytical formalism by including first-order effects from all these 'surfaces' to compute an exoplanet's effective radius, effective atmospheric thickness and spectral modulation for an atmosphere with a constant scaleheight. We show that the effective radius cannot be located below these 'surfaces' and that our formalism matches the formalism of Lecavelier des Etangs et al. in the case of a clear atmosphere. Our formalism explains why clouds and refraction reduce the contrast of spectral features, and why refraction decreases the Rayleigh scattering slope as wavelength increases, but also shows that these are common effects of all 'surfaces'. We introduce the concept of a 'surface' cross-section, the minimum mean cross-section that can be observed, as an index to characterize the location of 'surfaces' and provide a simple method to estimate their effects on the spectral modulation of homogeneous atmospheres. We finally devise a numerical recipe that extends our formalism to atmospheres with a non-constant scaleheight and arbitrary sources of opacity, a potentially necessary step to interpret observations.

The wheat R2R3-MYB transcription factor TaRIM1 participates in resistance response against the pathogen Rhizoctonia cerealis infection through regulating defense genes.

PubMed

Shan, Tianlei; Rong, Wei; Xu, Huijun; Du, Lipu; Liu, Xin; Zhang, Zengyan

2016-07-01

The necrotrophic fungus Rhizoctonia cerealis is a major pathogen of sharp eyespot that is a devastating disease of wheat (Triticum aestivum). Little is known about roles of MYB genes in wheat defense response to R. cerealis. In this study, TaRIM1, a R. cerealis-induced wheat MYB gene, was identified by transcriptome analysis, then cloned from resistant wheat CI12633, and its function and preliminary mechanism were studied. Sequence analysis showed that TaRIM1 encodes a R2R3-MYB transcription factor with transcription-activation activity. The molecular-biological assays revealed that the TaRIM1 protein localizes to nuclear and can bind to five MYB-binding site cis-elements. Functional dissection results showed that following R. cerealis inoculation, TaRIM1 silencing impaired the resistance of wheat CI12633, whereas TaRIM1 overexpression significantly increased resistance of transgenic wheat compared with susceptible recipient. TaRIM1 positively regulated the expression of five defense genes (Defensin, PR10, PR17c, nsLTP1, and chitinase1) possibly through binding to MYB-binding sites in their promoters. These results suggest that the R2R3-MYB transcription factor TaRIM1 positively regulates resistance response to R. cerealis infection through modulating the expression of a range of defense genes, and that TaRIM1 is a candidate gene to improve sharp eyespot resistance in wheat.

The wheat R2R3-MYB transcription factor TaRIM1 participates in resistance response against the pathogen Rhizoctonia cerealis infection through regulating defense genes

PubMed Central

Shan, Tianlei; Rong, Wei; Xu, Huijun; Du, Lipu; Liu, Xin; Zhang, Zengyan

2016-01-01

The necrotrophic fungus Rhizoctonia cerealis is a major pathogen of sharp eyespot that is a devastating disease of wheat (Triticum aestivum). Little is known about roles of MYB genes in wheat defense response to R. cerealis. In this study, TaRIM1, a R. cerealis-induced wheat MYB gene, was identified by transcriptome analysis, then cloned from resistant wheat CI12633, and its function and preliminary mechanism were studied. Sequence analysis showed that TaRIM1 encodes a R2R3-MYB transcription factor with transcription-activation activity. The molecular-biological assays revealed that the TaRIM1 protein localizes to nuclear and can bind to five MYB-binding site cis-elements. Functional dissection results showed that following R. cerealis inoculation, TaRIM1 silencing impaired the resistance of wheat CI12633, whereas TaRIM1 overexpression significantly increased resistance of transgenic wheat compared with susceptible recipient. TaRIM1 positively regulated the expression of five defense genes (Defensin, PR10, PR17c, nsLTP1, and chitinase1) possibly through binding to MYB-binding sites in their promoters. These results suggest that the R2R3-MYB transcription factor TaRIM1 positively regulates resistance response to R. cerealis infection through modulating the expression of a range of defense genes, and that TaRIM1 is a candidate gene to improve sharp eyespot resistance in wheat. PMID:27364458

Computational analysis of Pelton bucket tip erosion using digital image processing

NASA Astrophysics Data System (ADS)

Shrestha, Bim Prasad; Gautam, Bijaya; Bajracharya, Tri Ratna

2008-03-01

Erosion of hydro turbine components through sand laden river is one of the biggest problems in Himalayas. Even with sediment trapping systems, complete removal of fine sediment from water is impossible and uneconomical; hence most of the turbine components in Himalayan Rivers are exposed to sand laden water and subject to erode. Pelton bucket which are being wildly used in different hydropower generation plant undergoes erosion on the continuous presence of sand particles in water. The subsequent erosion causes increase in splitter thickness, which is supposed to be theoretically zero. This increase in splitter thickness gives rise to back hitting of water followed by decrease in turbine efficiency. This paper describes the process of measurement of sharp edges like bucket tip using digital image processing. Image of each bucket is captured and allowed to run for 72 hours; sand concentration in water hitting the bucket is closely controlled and monitored. Later, the image of the test bucket is taken in the same condition. The process is repeated for 10 times. In this paper digital image processing which encompasses processes that performs image enhancement in both spatial and frequency domain. In addition, the processes that extract attributes from images, up to and including the measurement of splitter's tip. Processing of image has been done in MATLAB 6.5 platform. The result shows that quantitative measurement of edge erosion of sharp edges could accurately be detected and the erosion profile could be generated using image processing technique.

The Physical Nature of the Sharp Spectral Feature at 7 keV Detected in 1H0707-495

NASA Technical Reports Server (NTRS)

Brandt, Niel

2005-01-01

XMM-Newton acquired data on the accepted target, 1H0707-495, on 2002 October 13 during revolution 0521. The observation was successful, with only about 5% data loss due to background flaring. We compared the data from this observation with earlier data taken on this Narrow-Line Seyfert 1 about two years before, performing interpretation studies in the context of the partial-covering model. Our second longer observation once again displays a sharp (< 200 eV) spectral drop above 7 keV. However, in comparison to the first observation, the edge depth and energy have changed significantly. In addition to changes in the edge parameters, the high-energy spectrum appears steeper. The changes in the high-energy spectrum can be adequately explained in terms of a partial-covering absorber out-flowing from the central region. The low-energy spectrum also shows significant long-term spectral variability, including (1) a substantial increase in the disk temperature, (2) detection of an approx. 0.9 keV emission feature, and (3) the presence of ionized absorption that was detected during the ASCA mission. The large increase in disk temperature, and the more modest rise in luminosity, can be understood if we consider a slim-disk model for 1H0707-495. In addition, the higher disk luminosity could be the driving force behind the outflow and the re-appearance of an ionized medium during the second XMM-Newton observation.

Variation of bar-press duration: where do new responses come from?

PubMed

Roberts, Seth; Gharib, Afshin

2006-06-01

Instrumental learning involves both variation and selection: variation of what the animal does, and selection by reward from among the variation. Four experiments with rats suggested a rule about how variation is controlled by recent events. Experiment 1 used the peak procedure. Measurements of bar-press durations showed a sharp increase in mean duration after the time that food was sometimes given. The increase was triggered by the omission of expected food. Our first explanation of the increase was that it was a frustration effect. Experiment 2 tested this explanation with a procedure in which the first response of a trial usually produced food, ending the trial. In Experiment 2, unlike Experiment 1, omission of expected food did not produce a large increase in bar-press duration, which cast doubt on the frustration explanation. Experiments 3 and 4 tested an alternative explanation: a decrease in expectation of reward increases variation. Both used two signals associated with different probabilities of reward. Bar presses were more variable in duration during the signal with the lower probability of reward, supporting this alternative. These experiments show how variation can be studied with ordinary equipment and responses.

Nodules of Cemented Sand Grains Within Martian Sandstone

NASA Image and Video Library

2016-03-11

This view from NASA Curiosity shows nodules exposed in sandstone that is part of the Stimson geological unit on Mount Sharp, Mars. The nodules can be seen to consist of grains of sand cemented together.

Confidence Hills Drill Powder in Scoop

NASA Image and Video Library

2014-11-04

This image from NASA Curiosity rover shows a sample of powdered rock extracted by the rover drill from the Confidence Hills target -- the first rock drilled after Curiosity reached the base of Mount Sharp in September 2014.

Lithium implantation at low temperature in silicon for sharp buried amorphous layer formation and defect engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oliviero, E.; David, M. L.; Beaufort, M. F.

The crystalline-to-amorphous transformation induced by lithium ion implantation at low temperature has been investigated. The resulting damage structure and its thermal evolution have been studied by a combination of Rutherford backscattering spectroscopy channelling (RBS/C) and cross sectional transmission electron microscopy (XTEM). Lithium low-fluence implantation at liquid nitrogen temperature is shown to produce a three layers structure: an amorphous layer surrounded by two highly damaged layers. A thermal treatment at 400 Degree-Sign C leads to the formation of a sharp amorphous/crystalline interfacial transition and defect annihilation of the front heavily damaged layer. After 600 Degree-Sign C annealing, complete recrystallization takes placemore » and no extended defects are left. Anomalous recrystallization rate is observed with different motion velocities of the a/c interfaces and is ascribed to lithium acting as a surfactant. Moreover, the sharp buried amorphous layer is shown to be an efficient sink for interstitials impeding interstitial supersaturation and {l_brace}311{r_brace} defect formation in case of subsequent neon implantation. This study shows that lithium implantation at liquid nitrogen temperature can be suitable to form a sharp buried amorphous layer with a well-defined crystalline front layer, thus having potential applications for defects engineering in the improvement of post-implantation layers quality and for shallow junction formation.« less

The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs

PubMed Central

Arieti, Fabiana; Gabus, Caroline; Tambalo, Margherita; Huet, Tiphaine; Round, Adam; Thore, Stéphane

2014-01-01

The Split Ends (SPEN) protein was originally discovered in Drosophila in the late 1990s. Since then, homologous proteins have been identified in eukaryotic species ranging from plants to humans. Every family member contains three predicted RNA recognition motifs (RRMs) in the N-terminal region of the protein. We have determined the crystal structure of the region of the human SPEN homolog that contains these RRMs—the SMRT/HDAC1 Associated Repressor Protein (SHARP), at 2.0 Å resolution. SHARP is a co-regulator of the nuclear receptors. We demonstrate that two of the three RRMs, namely RRM3 and RRM4, interact via a highly conserved interface. Furthermore, we show that the RRM3–RRM4 block is the main platform mediating the stable association with the H12–H13 substructure found in the steroid receptor RNA activator (SRA), a long, non-coding RNA previously shown to play a crucial role in nuclear receptor transcriptional regulation. We determine that SHARP association with SRA relies on both single- and double-stranded RNA sequences. The crystal structure of the SHARP–RRM fragment, together with the associated RNA-binding studies, extend the repertoire of nucleic acid binding properties of RRM domains suggesting a new hypothesis for a better understanding of SPEN protein functions. PMID:24748666

Behavior of healthcare workers after injuries from sharp instruments.

PubMed

Adib-Hajbaghery, Mohsen; Lotfi, Mohammad Sajjad

2013-09-01

Injuries with sharps are common occupational hazards for healthcare workers. Such injuries predispose the staff to dangerous infections such as hepatitis B, C and HIV. The present study was conducted to investigate the behaviors of healthcare workers in Kashan healthcare centers after needle sticks and injuries with sharps in 2012. A cross-sectional study was conducted on 298 healthcare workers of medical centers governed by Kashan University of Medical Sciences. A questionnaire was used in this study. The first part included questions about demographic characteristics. The second part of the questionnaire consisted of 16 items related to the sharp instrument injuries. For data analysis, descriptive and analytical statistics (chi-square, ANOVA and Pearson correlation coefficient) SPSS version 16.0 software was used. From a total of 298 healthcare workers, 114 (38.3%) had a history of injury from needles and sharp instruments in the last six months. Most needle stick and sharp instrument injuries had occurred among the operating room nurses and midwifes; 32.5% of injuries from sharp instruments occurred in the morning shift. Needles were responsible for 46.5% of injuries. The most common actions taken after needle stick injuries were compression (27.2%) and washing the area with soap and water (15.8%). Only 44.6% of the injured personnel pursued follow-up measures after a needle stick or sharp instrument injury. More than a half of the healthcare workers with needle stick or sharp instrument injury had refused follow-up for various reasons. The authorities should implement education programs along with protocols to be implemented after needle stick injuries or sharps.

Development of heat and drought related extreme weather events and their effect on winter wheat yields in Germany

NASA Astrophysics Data System (ADS)

Lüttger, Andrea B.; Feike, Til

2018-04-01

Climate change constitutes a major challenge for high productivity in wheat, the most widely grown crop in Germany. Extreme weather events including dry spells and heat waves, which negatively affect wheat yields, are expected to aggravate in the future. It is crucial to improve the understanding of the spatiotemporal development of such extreme weather events and the respective crop-climate relationships in Germany. Thus, the present study is a first attempt to evaluate the historic development of relevant drought and heat-related extreme weather events from 1901 to 2010 on county level (NUTS-3) in Germany. Three simple drought indices and two simple heat stress indices were used in the analysis. A continuous increase in dry spells over time was observed over the investigated periods from 1901-1930, 1931-1960, 1961-1990 to 2001-2010. Short and medium dry spells, i.e., precipitation-free periods longer than 5 and 8 days, respectively, increased more strongly compared to longer dry spells (longer than 11 days). The heat-related stress indices with maximum temperatures above 25 and 28 °C during critical wheat growth phases showed no significant increase over the first three periods but an especially sharp increase in the final 1991-2010 period with the increases being particularly pronounced in parts of Southwestern Germany. Trend analysis over the entire 110-year period using Mann-Kendall test revealed a significant positive trend for all investigated indices except for heat stress above 25 °C during flowering period. The analysis of county-level yield data from 1981 to 2010 revealed declining spatial yield variability and rather constant temporal yield variability over the three investigated (1981-1990, 1991-2000, and 2001-2010) decades. A clear spatial gradient manifested over time with variability in the West being much smaller than in the east of Germany. Correlating yield variability with the previously analyzed extreme weather indices revealed strong spatiotemporal fluctuations in explanatory power of the different indices over all German counties and the three time periods. Over the 30 years, yield deviations were increasingly well correlated with heat and drought-related indices, with the number of days with maximum temperature above 25 °C during anthesis showing a sharp increase in explanatory power over entire Germany in the final 2001-2010 period.

Regularity theory for general stable operators

NASA Astrophysics Data System (ADS)

Ros-Oton, Xavier; Serra, Joaquim

2016-06-01

We establish sharp regularity estimates for solutions to Lu = f in Ω ⊂Rn, L being the generator of any stable and symmetric Lévy process. Such nonlocal operators L depend on a finite measure on S n - 1, called the spectral measure. First, we study the interior regularity of solutions to Lu = f in B1. We prove that if f is Cα then u belong to C α + 2 s whenever α + 2 s is not an integer. In case f ∈L∞, we show that the solution u is C2s when s ≠ 1 / 2, and C 2 s - ɛ for all ɛ > 0 when s = 1 / 2. Then, we study the boundary regularity of solutions to Lu = f in Ω, u = 0 in Rn ∖ Ω, in C 1 , 1 domains Ω. We show that solutions u satisfy u /ds ∈C s - ɛ (Ω ‾) for all ɛ > 0, where d is the distance to ∂Ω. Finally, we show that our results are sharp by constructing two counterexamples.

Correlation between structural, electrical and magnetic properties of GdMnO3 bulk ceramics

NASA Astrophysics Data System (ADS)

Samantaray, S.; Mishra, D. K.; Pradhan, S. K.; Mishra, P.; Sekhar, B. R.; Behera, Debdhyan; Rout, P. P.; Das, S. K.; Sahu, D. R.; Roul, B. K.

2013-08-01

This paper reports the effect of sintering temperature on ferroelectric properties of GdMnO3 (GMO) bulk ceramics at room temperature prepared by the conventional solid state reaction route following slow step sintering schedule. Ferroelectric hysteresis loop as well as sharp dielectric anomaly in pure (99.999%) GMO sintered ceramics has been clearly observed. Samples sintered at 1350 °C become orthorhombic with Pbnm space group and showed frequency independent sharp dielectric anomalies at 373 K and a square type of novel ferroelectric hysteresis loop was observed at room temperature. Interestingly, dielectric anomalies and ferroelectric behavior were observed to be dependent upon sintering temperature of GdMnO3. Room temperature dielectric constant (ɛr) value at different frequencies is observed to be abnormally high. The magnetic field and temperature dependent magnetization show antiferromagnetic behavior at 40 K for both 1350 °C and 1700 °C sintered GMO. Present findings showed the possibility of application of GdMnO3 at room temperature as multifunctional materials.

An acoustofluidic micromixer based on oscillating sidewall sharp-edges.

PubMed

Huang, Po-Hsun; Xie, Yuliang; Ahmed, Daniel; Rufo, Joseph; Nama, Nitesh; Chen, Yuchao; Chan, Chung Yu; Huang, Tony Jun

2013-10-07

Rapid and homogeneous mixing inside a microfluidic channel is demonstrated via the acoustic streaming phenomenon induced by the oscillation of sidewall sharp-edges. By optimizing the design of the sharp-edges, excellent mixing performance and fast mixing speed can be achieved in a simple device, making our sharp-edge-based acoustic micromixer a promising candidate for a wide variety of applications.

Composite, ordered material having sharp surface features

DOEpatents

D'Urso, Brian R.; Simpson, John T.

2006-12-19

A composite material having sharp surface features includes a recessive phase and a protrusive phase, the recessive phase having a higher susceptibility to a preselected etchant than the protrusive phase, the composite material having an etched surface wherein the protrusive phase protrudes from the surface to form a sharp surface feature. The sharp surface features can be coated to make the surface super-hydrophobic.

The effect of clinorotation on structural and functional organization of assimilative tissues, cells and growth regulator activity in orchids of different age

NASA Astrophysics Data System (ADS)

Cherevchenko, T.; Zaimenko, N.; Sitnyanska, N.; Majko, T.; Grishko, M. M.

Ultrastructural analyses of assimilative tissues of the orchids, Cymbidium hybridum and Doritis pulcherrima, show that, in plants of different age, chloroplasts differ in structure and stage of membrane system development. Variability was found in the number, size and electron density of plastoglobuli, and in the orientation and length of thylakoid membranes. We consider significant the increase of the plastoglobuli which completely fill the stroma of chloroplasts in cells of old leaves and, under conditions of clinorotation (using a horizontal clinostat at 3 r.p.m.), are able to block membrane function. In the early stages of orchid plant development, the content of substances with auxin-like activity (as judged by bioassay) in the leaves was low, but increased with age. Clinorotation resulted in a sharp decrease of their content. There was a concomitant increase in the content of growth inhibitors of a phenolic nature.

[Attempted and completed homicide in Hamburg--a comparison of two six-year periods].

PubMed

Herrmann, Julia; Gehl, Axel; Püschel, Klaus; Anders, Sven

2010-01-01

The present study compared cases of attempted and completed homicide in Hamburg from 1984 to 1989 and from 1995 to 2000 (n = 887). Data collection was performed using the police records. Attempted homicide showed a significant increase (34.8% vs. 57.9%, P < 0.0001). The majority of the victims and offenders were male with the share of male victims increasing from 59.7% to 74.2% (P < 0.0001). The age of the victims and offenders ranged between 22 and 40 years in both periods. The share of persons with a nationality other than German increased both in the victims (23.1% vs. 37.2%, P < 0.0001) and in the offenders (26.8% vs. 37.2%, P < 0.0001). The most common motives were interpersonal conflicts and robbery. The most frequently used forms of violence were sharp force, blunt force and strangulation.

Unexpected molecular weight effect in polymer nanocomposites

DOE PAGES

Cheng, Shiwang; Holt, Adam P.; Wang, Huiqun; ...

2016-01-22

Here, the properties of the interfacial layer between the polymer matrix and nanoparticles largely determine the macroscopic properties of polymer nanocomposites (PNCs). Although the static thickness of the interfacial layer was found to increase with the molecular weight (MW), the influence of MW on segmental relaxation and the glass transition in this layer remains to be explored. In this Letter, we show an unexpected MW dependence of the interfacial properties in PNC with attractive polymer-nanoparticle interactions: the thickness of the interfacial layer with hindered segmental relaxation decreases as MW increases, in sharp constrast to theoretical predictions. Further analyses reveal amore » reduction in mass density of the interfacial layer with increasing MW, which can explain these unexpected dynamic effects. Our observations call for a significant revision of the current understandings of PNCs and suggest interesting ways to tailor their properties.« less

Graphene‐Nanowall‐Decorated Carbon Felt with Excellent Electrochemical Activity Toward VO2 +/VO2+ Couple for All Vanadium Redox Flow Battery

PubMed Central

Li, Wenyue; Zhang, Zhenyu; Bian, Haidong; Ng, Tsz‐Wai

2015-01-01

3D graphene‐nanowall‐decorated carbon felts (CF) are synthesized via an in situ microwave plasma enhanced chemical vapor deposition method and used as positive electrode for vanadium redox flow battery (VRFB). The carbon fibers in CF are successfully wrapped by vertically grown graphene nanowalls, which not only increase the electrode specific area, but also expose a high density of sharp graphene edges with good catalytic activities to the vanadium ions. As a result, the VRFB with this novel electrode shows three times higher reaction rate toward VO2 +/VO2+ redox couple and 11% increased energy efficiency over VRFB with an unmodified CF electrode. Moreover, this designed architecture shows excellent stability in the battery operation. After 100 charging–discharging cycles, the electrode not only shows no observable morphology change, it can also be reused in another battery and practical with the same performance. It is believed that this novel structure including the synthesis procedure will provide a new developing direction for the VRFB electrode. PMID:27774399

Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length.

PubMed

Newcombe, Estella A; Ruff, Kiersten M; Sethi, Ashish; Ormsby, Angelique R; Ramdzan, Yasmin M; Fox, Archa; Purcell, Anthony W; Gooley, Paul R; Pappu, Rohit V; Hatters, Danny M

2018-05-11

Soluble huntingtin exon 1 (Httex1) with expanded polyglutamine (polyQ) engenders neurotoxicity in Huntington's disease. To uncover the physical basis of this toxicity, we performed structural studies of soluble Httex1 for wild-type and mutant polyQ lengths. Nuclear magnetic resonance experiments show evidence for conformational rigidity across the polyQ region. In contrast, hydrogen-deuterium exchange shows absence of backbone amide protection, suggesting negligible persistence of hydrogen bonds. The seemingly conflicting results are explained by all-atom simulations, which show that Httex1 adopts tadpole-like structures with a globular head encompassing the N-terminal amphipathic and polyQ regions and the tail encompassing the C-terminal proline-rich region. The surface area of the globular domain increases monotonically with polyQ length. This stimulates sharp increases in gain-of-function interactions in cells for expanded polyQ, and one of these interactions is with the stress-granule protein Fus. Our results highlight plausible connections between Httex1 structure and routes to neurotoxicity. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Graphene-Nanowall-Decorated Carbon Felt with Excellent Electrochemical Activity Toward VO2+/VO2+ Couple for All Vanadium Redox Flow Battery.

PubMed

Li, Wenyue; Zhang, Zhenyu; Tang, Yongbing; Bian, Haidong; Ng, Tsz-Wai; Zhang, Wenjun; Lee, Chun-Sing

2016-04-01

3D graphene-nanowall-decorated carbon felts (CF) are synthesized via an in situ microwave plasma enhanced chemical vapor deposition method and used as positive electrode for vanadium redox flow battery (VRFB). The carbon fibers in CF are successfully wrapped by vertically grown graphene nanowalls, which not only increase the electrode specific area, but also expose a high density of sharp graphene edges with good catalytic activities to the vanadium ions. As a result, the VRFB with this novel electrode shows three times higher reaction rate toward VO 2 + /VO 2+ redox couple and 11% increased energy efficiency over VRFB with an unmodified CF electrode. Moreover, this designed architecture shows excellent stability in the battery operation. After 100 charging-discharging cycles, the electrode not only shows no observable morphology change, it can also be reused in another battery and practical with the same performance. It is believed that this novel structure including the synthesis procedure will provide a new developing direction for the VRFB electrode.

Predation and protection in the macroevolutionary history of conifer cones

PubMed Central

Leslie, Andrew B.

2011-01-01

Conifers are an excellent group in which to explore how changing ecological interactions may have influenced the allocation of reproductive tissues in seed plants over long time scales, because of their extensive fossil record and their important role in terrestrial ecosystems since the Palaeozoic. Measurements of individual conifer pollen-producing and seed-producing cones from the Pennsylvanian to the Recent show that the relative amount of tissue invested in pollen cones has remained constant through time, while seed cones show a sharp increase in proportional tissue investment in the Jurassic that has continued to intensify to the present day. Since seed size in conifers has remained similar through time, this increase reflects greater investment in protective cone tissues such as robust, tightly packed scales. This shift in morphology and tissue allocation is broadly concurrent with the appearance of new vertebrate groups capable of browsing in tree canopies, as well as a diversification of insect-feeding strategies, suggesting that an important change in plant–animal interactions occurred over the Mesozoic that favoured an increase in seed cone protective tissues. PMID:21345864

Post-annealing effect on optical absorbance of hydrothermally grown zinc oxide nanorods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mohar, Rahmat Setiawan; Djuhana, Dede; Imawan, Cuk

In this study, the optical absorbance of zinc oxide (ZnO) nanorods was investigated. The ZnO thin film were deposited on indium tin oxide (ITO) layers using ultrasonic spray pyrolysis (USP) method and then grown by hydrothermal method. In order to improve the optical absorbance, the ZnO nanorods were then post-annealed for one hour at three different of temperatures, namely 250, 400, and 500 °C. The X-ray diffraction (XRD) spectra and FESEM images show that the ZnO nanorods have the hexagonal wurtzite crystal structure and the increasing of post-annealing temperature resulted in the increasing of crystallite size from 38.2 nm to 48.4 nm.more » The UV-vis spectra shows that all samples of ZnO nanorods exhibited the identical sharp absorption edge at 390 nm indicating that all samples have the same bandgap. The post-annealing process seemed to decrease the optical absorbance in the region of 300-550 nm and increase the optical absorbance in the region of 550-700 nm..« less

A variational theory of Hall effect of Anderson lattice model: Application to colossal magnetoresistance manganites (Re1-x Ax MnO3)

NASA Astrophysics Data System (ADS)

Panwar, Sunil; Kumar, Vijay; Singh, Ishwar

2017-10-01

An anomalous Hall constant RH has been observed in various rare earth manganites doped with alkaline earths namely Re1-xAxMnO3 (where Re = La, Pr, Nd etc., and A = Ca, Sr, Ba etc.) which exhibit colossal magnetoresistance (CMR), metal- insulator transition and many other poorly understood phenomena. We show that this phenomenon of anomalous Hall constant can be understood using two band (ℓ-b) Anderson lattice model Hamiltonian alongwith (ℓ-b) hybridization recently studied by us for manganites in the strong electron-lattice Jahn-Teller (JT) coupling regime an approach similar to the two - fluid models. We use a variational method in this work to study the temperature variation of Hall constant RH (T) in these compounds. We have already used this variational method to study the zero field electrical resistivity ρ (T) and magnetic susceptibility of doped CMR manganites. In the present study, we find that the Hall constant RH (T) reduces with increasing magnetic field parameters h&m and the metal-insulator transition temperature (Tρ) shifts towards higher temperature region. We have also observed the role of the model parameters e.g. local Coulomb repulsion U, Hund's rule coupling JH between eg spins and t2g spins, ferromagnetic nearest neighbor exchange coupling JF between t2g core spins and hybridization Vk between ℓ-polarons and d-electrons on Hall constant RH (T) of these materials at different magnetic fields. Here we find that RH (T) for a particular value of h and m shows a rapid initial increase, followed by a sharp peak at low temperature say 50 K in our case and a slow decrease at high temperatures, resembling with the key feature of many CMR compounds like La0.8Ba0.2 MnO3.The magnitude of RH (T) reduces and the anomaly (sharp peak) in RH becomes broader and shifts towards higher temperature region on increasing Vk or JH or doping x and even vanishes on further increasing these parameters. Our results of anomalous Hall constant (RH) have same qualitative behavior as the zero-field electrical resistivity. Moreover Hall Constant (RH) shows positive values indicating that the carriers in these manganites are holes.

An acoustofluidic micromixer based on oscillating sidewall sharp-edges†

PubMed Central

Huang, Po-Hsun; Xie, Yuliang; Ahmed, Daniel; Rufo, Joseph; Nama, Nitesh; Chen, Yuchao; Chan, Chung Yu; Huang, Tony Jun

2014-01-01

Rapid and homogeneous mixing inside a microfluidic channel is demonstrated via the acoustic streaming phenomenon induced by the oscillation of sidewall sharp-edges. By optimizing the design of the sharp-edges, excellent mixing performance and fast mixing speed can be achieved in a simple device, making our sharp-edge-based acoustic micromixer a promising candidate for a wide variety of applications. PMID:23896797

SHARP User Manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yu, Y. Q.; Shemon, E. R.; Thomas, J. W.

SHARP is an advanced modeling and simulation toolkit for the analysis of nuclear reactors. It is comprised of several components including physical modeling tools, tools to integrate the physics codes for multi-physics analyses, and a set of tools to couple the codes within the MOAB framework. Physics modules currently include the neutronics code PROTEUS, the thermal-hydraulics code Nek5000, and the structural mechanics code Diablo. This manual focuses on performing multi-physics calculations with the SHARP ToolKit. Manuals for the three individual physics modules are available with the SHARP distribution to help the user to either carry out the primary multi-physics calculationmore » with basic knowledge or perform further advanced development with in-depth knowledge of these codes. This manual provides step-by-step instructions on employing SHARP, including how to download and install the code, how to build the drivers for a test case, how to perform a calculation and how to visualize the results. Since SHARP has some specific library and environment dependencies, it is highly recommended that the user read this manual prior to installing SHARP. Verification tests cases are included to check proper installation of each module. It is suggested that the new user should first follow the step-by-step instructions provided for a test problem in this manual to understand the basic procedure of using SHARP before using SHARP for his/her own analysis. Both reference output and scripts are provided along with the test cases in order to verify correct installation and execution of the SHARP package. At the end of this manual, detailed instructions are provided on how to create a new test case so that user can perform novel multi-physics calculations with SHARP. Frequently asked questions are listed at the end of this manual to help the user to troubleshoot issues.« less

Creating Resilient IT: How the Sign-Out Sheet Shows Clinicians Make Healthcare Work

PubMed Central

Nemeth, Christopher; Nunnally, Mark; O’Connor, Michael; Cook, Richard

2006-01-01

Information technology (IT) systems have been described as brittle and prone to automation surprises. Recent report of information system failure, particularly computerized physician order entry (CPOE) systems, shows the result of IT failure in actual practice. Such mismatches with healthcare work requirements necessitate improvement to IT research and development. Efforts to develop successful IT systems for healthcare’s sharp end must incorporate properties that reflect workers’ initiative in respose to domain constraints. Resilience is the feature of some systems that makes it possible for them to respond to sudden, unanticipated demands for performance and return to normal operation quickly, with minimum decrement in performance. Workers create resilience at healthcare’s sharp end by daily confronting constraints and obstacles that need to be surmounted in order to accomplish results. The sign-out sheet is an example of resilience that can be used to guide IT development. PMID:17238408

Vertical versus Lateral Two-Dimensional Heterostructures: On the Topic of Atomically Abrupt p/n-Junctions.

PubMed

Zhou, Ruiping; Ostwal, Vaibhav; Appenzeller, Joerg

2017-08-09

The key appeal of two-dimensional (2D) materials such as graphene, transition metal dichalcogenides (TMDs), or phosphorene for electronic applications certainly lies in their atomically thin nature that offers opportunities for devices beyond conventional transistors. It is also this property that makes them naturally suited for a type of integration that is not possible with any three-dimensional (3D) material, that is, forming heterostructures by stacking dissimilar 2D materials together. Recently, a number of research groups have reported on the formation of atomically sharp p/n-junctions in various 2D heterostructures that show strong diode-type rectification. In this article, we will show that truly vertical heterostructures do exhibit much smaller rectification ratios and that the reported results on atomically sharp p/n-junctions can be readily understood within the framework of the gate and drain voltage response of Schottky barriers that are involved in the lateral transport.

Modelling tooth–prey interactions in sharks: the importance of dynamic testing

PubMed Central

Farina, Stacy C.; Brash, Jeffrey; Summers, Adam P.

2016-01-01

The shape of shark teeth varies among species, but traditional testing protocols have revealed no predictive relationship between shark tooth morphology and performance. We developed a dynamic testing device to quantify cutting performance of teeth. We mimicked head-shaking behaviour in feeding large sharks by attaching teeth to the blade of a reciprocating power saw fixed in a custom-built frame. We tested three tooth types at biologically relevant speeds and found differences in tooth cutting ability and wear. Teeth from the bluntnose sixgill (Hexanchus griseus) showed poor cutting ability compared with tiger (Galeocerdo cuvier), sandbar (Carcharhinus plumbeus) and silky (C. falciformis) sharks, but they also showed no wear with repeated use. Some shark teeth are very sharp at the expense of quickly dulling, while others are less sharp but dull more slowly. This demonstrates that dynamic testing is vital to understanding the performance of shark teeth. PMID:27853592

Microstructural and hardness investigations on a dissimilar metal weld between low alloy steel and Alloy 82 weld metal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Z.R., E-mail: raymix@aliyun.com

The investigation on microstructure and hardness at the fusion boundary (FB) region of a dissimilar metal weld (DMW) between low alloy steel (LAS) A508-III and Alloy 82 weld metal (WM) was carried out. The results indicated that there were two kinds of FBs, martensite FB and sharp FB, with obvious different microstructures, alternately distributed in the same FB. The martensite FB region had a gradual change of elemental concentration across FB, columnar WM grains with high length/width ratios, a thick martensite layer and a wide heat affected zone (HAZ) with large prior austenite grains. By comparison, the sharp FB regionmore » had a relatively sharp change of elemental concentration across the FB, WM grains with low length/width ratios and a narrow HAZ with smaller prior austenite grains. The martensite possessed a K-S orientation relationship with WM grains, while no orientation relationship was found between the HAZ grains and WM grains at the sharp FB. Compared with sharp FB there were much more Σ3 boundaries in the HAZ beside martensite FB. The hardness maximum of the martensite FB was much higher than that of the sharp FB, which was attributed to the martensite layer at the martensite FB. - Highlights: •Martensite and sharp FBs with different microstructures were found in the same FB. •There were high length/width-ratio WM grains and a wide HAZ beside martensite FB. •There were low length/width-ratio WM grains and a narrow HAZ beside sharp FB. •Compared with sharp FB, there were much more Σ3 boundaries in HAZ of martensite FB. •Hardness maximium of martensite FB was much higher than that of sharp FB.« less

The State of the Trade: Global Arms Transfer Patterns in the 1980s

DTIC Science & Technology

1986-01-01

and advertising , and the pressure to secure new orders is reported to be intense. There has been an increase in the number and frequency of military...obvious consequences is a sharp increase in the intensity of supply-side competition. The major producers are placing far more emphasis on marketing

LONG-TERM CHANGES IN WATERSHED NUTRIENT INPUTS AND RIVERINE EXPORTS IN THE NEUSE RIVER, NORTH CAROLINA. (U915590)

EPA Science Inventory

We compared patterns of historical watershed nutrient inputs with in-river nutrient loads for the Neuse River, NC. Basin-wide sources of both nitrogen and phosphorus have increased substantially during the past century, marked by a sharp increase in the last 10 years resulting...

Impact of energy sector growth on perceived transportation safety in the seventeen-county oil region of western North Dakota : a three-year case study.

DOT National Transportation Integrated Search

2015-10-01

The sharp increase in travel volumes, shift in traffic mix, and large increases in crashes have transformed : the traffic environment in the oil region of western North Dakota. Roads once used for local access and : agricultural purposes now regularl...

Funding the Arms Race: A Case Study of Student Athletic Fees

ERIC Educational Resources Information Center

Denhart, Matthew; Ridpath, David

2011-01-01

Intercollegiate athletics (ICA) is becoming an increasingly expensive venture at America's colleges and universities. Some big-time athletic powers have athletic budgets exceeding $100 million annually, and even schools with lesser reputations in the NCAA's Divisions II and III have had sharp increases in athletic budgets in recent years.…

Impact of energy sector growth on perceived transportation safety in the seventeen-county oil region of western North Dakota : a follow-up study.

DOT National Transportation Integrated Search

2014-10-01

The sharp increase in travel volumes, shift in traffic mix, and large increases in crashes have transformed : the travel environment in the oil region of western North Dakota. Roads once used for local access and : agricultural purposes now mostly se...

Higher Education Policies and Overeducation in Turkey

ERIC Educational Resources Information Center

Habibi, Nader

2017-01-01

In the past two decades Turkey has experienced a rapid increase in higher education student enrollment. This sharp increase in access to higher education has satisfied a strong social demand for university education but it has led to a growing surplus of university graduates who cannot find adequate jobs. As a result Turkey has entered an…

Climate Change and Its Impact on the Eco-Environment of the Three-Rivers Headwater Region on the Tibetan Plateau, China.

PubMed

Jiang, Chong; Zhang, Linbo

2015-09-25

This study analyzes the impact of climate change on the eco-environment of the Three-Rivers Headwater Region (TRHR), Tibetan Plateau, China. Temperature and precipitation experienced sharp increases in this region during the past 57 years. A dramatic increase in winter temperatures contributed to a rise in average annual temperatures. Moreover, annual runoff in the Lancang (LRB) and Yangtze (YARB) river basins showed an increasing trend, compared to a slight decrease in the Yellow River Basin (YRB). Runoff is predominantly influenced by rainfall, which is controlled by several monsoon systems. The water temperature in the YRB and YARB increased significantly from 1958 to 2007 (p < 0.001), driven by air temperature changes. Additionally, owing to warming and wetting trends in the TRHR, the net primary productivity (NPP) and normalized difference vegetation index (NDVI) showed significant increasing trends during the past half-century. Furthermore, although an increase in water erosion due to rainfall erosivity was observed, wind speeds declined significantly, causing a decline in wind erosion, as well as the frequency and duration of sandstorms. A clear regional warming trend caused an obvious increasing trend in glacier runoff, with a maximum value observed in the 2000s.

Climate Change and Its Impact on the Eco-Environment of the Three-Rivers Headwater Region on the Tibetan Plateau, China

PubMed Central

Jiang, Chong; Zhang, Linbo

2015-01-01

This study analyzes the impact of climate change on the eco-environment of the Three-Rivers Headwater Region (TRHR), Tibetan Plateau, China. Temperature and precipitation experienced sharp increases in this region during the past 57 years. A dramatic increase in winter temperatures contributed to a rise in average annual temperatures. Moreover, annual runoff in the Lancang (LRB) and Yangtze (YARB) river basins showed an increasing trend, compared to a slight decrease in the Yellow River Basin (YRB). Runoff is predominantly influenced by rainfall, which is controlled by several monsoon systems. The water temperature in the YRB and YARB increased significantly from 1958 to 2007 (p < 0.001), driven by air temperature changes. Additionally, owing to warming and wetting trends in the TRHR, the net primary productivity (NPP) and normalized difference vegetation index (NDVI) showed significant increasing trends during the past half-century. Furthermore, although an increase in water erosion due to rainfall erosivity was observed, wind speeds declined significantly, causing a decline in wind erosion, as well as the frequency and duration of sandstorms. A clear regional warming trend caused an obvious increasing trend in glacier runoff, with a maximum value observed in the 2000s. PMID:26404333

Increasing physical activity levels in primary school physical education: The SHARP Principles Model.

PubMed

Powell, Emma; Woodfield, Lorayne A; Nevill, Alan M

2016-06-01

To evaluate the effectiveness of a one-year teaching intervention to increase moderate to vigorous physical activity (MVPA) during primary school physical education (PE). A quasi-experimental, non-equivalent group design involving four classes from two primary schools in the West Midlands, UK. In March 2014 schools were selected through purposive sampling to match schools in terms of size and demographics (baseline, n = 111: post-intervention, n = 95); data were collected from children in school years 3 and 4 (aged 7 to 9 years). The intervention involved developing teacher effectiveness through the SHARP Principles Model which was grounded in the Self Determination Theory (SDT), the Social Ecological Model (SEM) and three key ingredients from the Behaviour Change Taxonomy (BCT). MVPA was assessed at baseline and four weeks post-intervention using the System for Observing Fitness and Instruction Time (SOFIT). Four individual teacher interviews were conducted with the intervention school, to explore teachers' perceptions of the intervention. A two-way ANOVA (Analysis of Variance) indicated large interaction effect sizes for time spent in MVPA (F(1, 27) = 11.07, p = 0.003, ηp (2) = .316) and vigorous activity (VPA) (F = (1,27) = 8.557, p = .007, ηp (2) = .263). PA in the intervention school increased significantly whereas in the control school MVPA remained relatively constant and VPA decreased. The qualitative findings revealed two main emergent themes: a paradigm shift and teacher's developing pedagogy. The intervention was effective in increasing MVPA in PE. Recommendations based on this evaluation would be for the SHARP Principles Model to be replicated and evaluated on a wider scale across a variety of contexts.

Increasing physical activity levels in primary school physical education: The SHARP Principles Model

PubMed Central

Powell, Emma; Woodfield, Lorayne A.; Nevill, Alan M.

2015-01-01

Objectives: To evaluate the effectiveness of a one-year teaching intervention to increase moderate to vigorous physical activity (MVPA) during primary school physical education (PE). Methods: A quasi-experimental, non-equivalent group design involving four classes from two primary schools in the West Midlands, UK. In March 2014 schools were selected through purposive sampling to match schools in terms of size and demographics (baseline, n = 111: post-intervention, n = 95); data were collected from children in school years 3 and 4 (aged 7 to 9 years). The intervention involved developing teacher effectiveness through the SHARP Principles Model which was grounded in the Self Determination Theory (SDT), the Social Ecological Model (SEM) and three key ingredients from the Behaviour Change Taxonomy (BCT). MVPA was assessed at baseline and four weeks post-intervention using the System for Observing Fitness and Instruction Time (SOFIT). Four individual teacher interviews were conducted with the intervention school, to explore teachers' perceptions of the intervention. Results: A two-way ANOVA (Analysis of Variance) indicated large interaction effect sizes for time spent in MVPA (F(1, 27) = 11.07, p = 0.003, ηp2 = .316) and vigorous activity (VPA) (F = (1,27) = 8.557, p = .007, ηp2 = .263). PA in the intervention school increased significantly whereas in the control school MVPA remained relatively constant and VPA decreased. The qualitative findings revealed two main emergent themes: a paradigm shift and teacher's developing pedagogy. Conclusions: The intervention was effective in increasing MVPA in PE. Recommendations based on this evaluation would be for the SHARP Principles Model to be replicated and evaluated on a wider scale across a variety of contexts. PMID:26844179

CCR5 gene polymorphism is a genetic risk factor for radiographic severity of rheumatoid arthritis.

PubMed

Han, S W; Sa, K H; Kim, S I; Lee, S I; Park, Y W; Lee, S S; Yoo, W H; Soe, J S; Nam, E J; Lee, J; Park, J Y; Kang, Y M

2012-11-01

The chemokine receptor [C-C chemokine receptor 5 (CCR5)] is expressed on diverse immune effecter cells and has been implicated in the pathogenesis of rheumatoid arthritis (RA). This study sought to determine whether single-nucleotide polymorphisms (SNPs) in the CCR5 gene and their haplotypes were associated with susceptibility to and severity of RA. Three hundred fifty-seven patients with RA and 383 healthy unrelated controls were recruited. Using a pyrosequencing assay, we examined four polymorphisms -1118 CTAT(ins) (/del) (rs10577983), 303 A>G (rs1799987), 927 C>T (rs1800024), and 4838 G>T (rs1800874) of the CCR5 gene, which were distributed over the promoter region as well as the 5' and 3' untranslated regions. No significant difference in the genotype, allele, and haplotype frequencies of the four selected SNPs was observed between RA patients and controls. CCR5 polymorphisms of -1118 CTAT(del) (P = 0.012; corrected P = 0.048) and 303 A>G (P = 0.012; corrected P = 0.048) showed a significant association with radiographic severity in a recessive model, and, as a result of multivariate logistic regression analysis, were found to be an independent predictor of radiographic severity. When we separated the erosion score from the total Sharp score, the statistical significance of CCR5 polymorphisms showed an increase; -1118 CTAT(ins) (/del) (P = 0.007; corrected P = 0.028) and 303 A>G (P = 0.007; corrected P = 0.028). Neither SNPs nor haplotypes of the CCR5 gene showed a significant association with joint space narrowing score. These results indicate that genetic polymorphisms of CCR5 are an independent risk factor for radiographic severity denoted by modified Sharp score, particularly joint erosion in RA. © 2012 John Wiley & Sons A/S.

Including Thermal Fluctuations in Actomyosin Stable States Increases the Predicted Force per Motor and Macroscopic Efficiency in Muscle Modelling

PubMed Central

2016-01-01

Muscle contractions are generated by cyclical interactions of myosin heads with actin filaments to form the actomyosin complex. To simulate actomyosin complex stable states, mathematical models usually define an energy landscape with a corresponding number of wells. The jumps between these wells are defined through rate constants. Almost all previous models assign these wells an infinite sharpness by imposing a relatively simple expression for the detailed balance, i.e., the ratio of the rate constants depends exponentially on the sole myosin elastic energy. Physically, this assumption corresponds to neglecting thermal fluctuations in the actomyosin complex stable states. By comparing three mathematical models, we examine the extent to which this hypothesis affects muscle model predictions at the single cross-bridge, single fiber, and organ levels in a ceteris paribus analysis. We show that including fluctuations in stable states allows the lever arm of the myosin to easily and dynamically explore all possible minima in the energy landscape, generating several backward and forward jumps between states during the lifetime of the actomyosin complex, whereas the infinitely sharp minima case is characterized by fewer jumps between states. Moreover, the analysis predicts that thermal fluctuations enable a more efficient contraction mechanism, in which a higher force is sustained by fewer attached cross-bridges. PMID:27626630

Brush seal bristle flexure and hard-rub characteristics

NASA Technical Reports Server (NTRS)

Hendricks, Robert C.; Carlile, Julie A.; Liang, Anita D.

1993-01-01

The bristles of a 38.1-mm (1.5-in.) diameter brush seal were flexed by a tapered, 40-tooth rotor operating at 2600 rpm that provided sharp leading-edge impact of the bristles with hard rubbing of the rotor lands. Three separate tests were run with the same brush accumulating over 1.3 x 10(exp 9) flexure cycles while deteriorating 0.2 mm (0.008 in.) radially. In each, the test bristle incursion depth varied from 0.130 to 0.025 mm (0.005 to 0.001 in.) or less (start to stop), and in the third test the rotor was set 0.25 mm (0.010 in.) eccentric. Runout varied from 0.025 to 0.076 mm (0.001 to 0.003 in.) radially. The bristles wore but did not pull out, fracture, or fragment. Bristle and rotor wear debris were deposited as very fine, nearly amorphous, highly porous materials at the rotor groove leading edges and within the rotor grooves. The land leading edges showed irregular wear and the beginning of a convergent groove that exhibited sharp, detailed wear at the land trailing edges. Surface grooving, burnishing, 'whipping', and hot spots and streaks were found. With a smooth-plug rotor, post-test leakage increased 30 percent over pretest leakage.

Brush seal low surface speed hard-rub characteristics

NASA Technical Reports Server (NTRS)

Hendricks, Robert C.; Carlile, Julie A.; Liang, Anita D.

1993-01-01

The bristles of a 38.1-mm (1.5-in.) diameter brush seal were flexed by a tapered, 40-tooth rotor operating at 2600 rpm that provided sharp leading-edge impact of the bristles with hard rubbing of the rotor lands. Three separate tests were run with the same brush accumulating over 1.3 x 10(exp 9) flexure cycles while deteriorating 0.2 mm (0.008 in.) radially. In each, the test bristle incursion depth varied from 0.130 to 0.025 mm (0.005 to 0.001 in.) or less (start to stop), and in the third test the rotor was set 0.25 mm (0.010 in.) eccentric. Runout varied from 0.025 to 0.076 mm (0.001 to 0.003 in.) radially. The bristles wore but did not pull out, fracture, or fragment. Bristle and rotor wear debris were deposited as very fine, nearly amorphous, highly porous materials at the rotor groove leading edges and within the rotor grooves. The land leading edges showed irregular wear and the beginning of a convergent groove that exhibited sharp, detailed wear at the land trailing edges. Surface grooving, burnishing, 'whipping,' and hot spots and streaks were found. With a smooth-plug rotor, post-test leakage increased 30 percent over pretest leakage.

Brush seal bristle flexure and hard-rub characteristics

NASA Technical Reports Server (NTRS)

Hendricks, Robert C.; Carlile, Julie A.; Liang, Anita D.

1992-01-01

The bristles of a 38.1-mm (1.5-in) diameter brush seal were flexed by a tapered, 40-tooth rotor operating at 2600 rpm that provided sharp leading-edge impact of the bristles with hard rubbing of the rotor lands. Three separate tests were run with the same brush accumulating over 1.3 x 10(exp 9) flexure cycles while deteriorating 0.2 mm (0.008 in) radially. In each, the test bristle incursion depth varied from 0.130 to 0.025 mm (0.005 to 0.001 in) or less (start to stop), and in the third test the rotor was set 0.25 mm (0.010 in) eccentric. Runout varied from 0.025 to 0.076 mm (0.001 to 0.003 in) radially. The bristles wore but did not pull out, fracture, or fragment. Bristle and rotor wear debris were deposited as very fine, nearly amorphous, highly porous materials at the rotor groove leading edges and within the rotor grooves. The land leading edges showed irregular wear and the beginning of a convergent groove that exhibited sharp, detailed wear at the land trailing edges. Surface grooving, burnishing, 'whipping,' and hot spots and streaks were found. With a smooth-plug rotor post-test leakage increased 30 percent over pretest leakage.

Brush seal bristle flexure and hard-rub characteristics

NASA Astrophysics Data System (ADS)

Hendricks, Robert C.; Carlile, Julie A.; Liang, Anita D.

1992-08-01

The bristles of a 38.1-mm (1.5-in) diameter brush seal were flexed by a tapered, 40-tooth rotor operating at 2600 rpm that provided sharp leading-edge impact of the bristles with hard rubbing of the rotor lands. Three separate tests were run with the same brush accumulating over 1.3 x 10(exp 9) flexure cycles while deteriorating 0.2 mm (0.008 in) radially. In each, the test bristle incursion depth varied from 0.130 to 0.025 mm (0.005 to 0.001 in) or less (start to stop), and in the third test the rotor was set 0.25 mm (0.010 in) eccentric. Runout varied from 0.025 to 0.076 mm (0.001 to 0.003 in) radially. The bristles wore but did not pull out, fracture, or fragment. Bristle and rotor wear debris were deposited as very fine, nearly amorphous, highly porous materials at the rotor groove leading edges and within the rotor grooves. The land leading edges showed irregular wear and the beginning of a convergent groove that exhibited sharp, detailed wear at the land trailing edges. Surface grooving, burnishing, 'whipping,' and hot spots and streaks were found. With a smooth-plug rotor post-test leakage increased 30 percent over pretest leakage.

Brush seal bristle flexure and hard-rub characteristics

NASA Astrophysics Data System (ADS)

Hendricks, Robert C.; Carlile, Julie A.; Liang, Anita D.

1993-10-01

The bristles of a 38.1-mm (1.5-in.) diameter brush seal were flexed by a tapered, 40-tooth rotor operating at 2600 rpm that provided sharp leading-edge impact of the bristles with hard rubbing of the rotor lands. Three separate tests were run with the same brush accumulating over 1.3 x 10(exp 9) flexure cycles while deteriorating 0.2 mm (0.008 in.) radially. In each, the test bristle incursion depth varied from 0.130 to 0.025 mm (0.005 to 0.001 in.) or less (start to stop), and in the third test the rotor was set 0.25 mm (0.010 in.) eccentric. Runout varied from 0.025 to 0.076 mm (0.001 to 0.003 in.) radially. The bristles wore but did not pull out, fracture, or fragment. Bristle and rotor wear debris were deposited as very fine, nearly amorphous, highly porous materials at the rotor groove leading edges and within the rotor grooves. The land leading edges showed irregular wear and the beginning of a convergent groove that exhibited sharp, detailed wear at the land trailing edges. Surface grooving, burnishing, 'whipping', and hot spots and streaks were found. With a smooth-plug rotor, post-test leakage increased 30 percent over pretest leakage.

Brush seal low surface speed hard-rub characteristics

NASA Astrophysics Data System (ADS)

Hendricks, Robert C.; Carlile, Julie A.; Liang, Anita D.

1993-06-01

The bristles of a 38.1-mm (1.5-in.) diameter brush seal were flexed by a tapered, 40-tooth rotor operating at 2600 rpm that provided sharp leading-edge impact of the bristles with hard rubbing of the rotor lands. Three separate tests were run with the same brush accumulating over 1.3 x 10(exp 9) flexure cycles while deteriorating 0.2 mm (0.008 in.) radially. In each, the test bristle incursion depth varied from 0.130 to 0.025 mm (0.005 to 0.001 in.) or less (start to stop), and in the third test the rotor was set 0.25 mm (0.010 in.) eccentric. Runout varied from 0.025 to 0.076 mm (0.001 to 0.003 in.) radially. The bristles wore but did not pull out, fracture, or fragment. Bristle and rotor wear debris were deposited as very fine, nearly amorphous, highly porous materials at the rotor groove leading edges and within the rotor grooves. The land leading edges showed irregular wear and the beginning of a convergent groove that exhibited sharp, detailed wear at the land trailing edges. Surface grooving, burnishing, 'whipping,' and hot spots and streaks were found. With a smooth-plug rotor, post-test leakage increased 30 percent over pretest leakage.

Tuning the metamagnetism in a metallic helical antiferromagnet

NASA Astrophysics Data System (ADS)

Ma, S. C.; Liu, K.; Ma, C. C.; Ge, Q.; Zhang, J. T.; Hu, Y. F.; Liu, E. K.; Zhong, Z. C.

2017-12-01

The antiferromagnetic (AFM)-ferromagnetic (FM) conversion in martensite was observed in Mn/Ni-substitution upon FM elements, such as Fe or Co, in MnNiGe helical antiferromagnets. Here, we report an AFM-FM conversion and consequently a sharp magnetic-field-driven metamagnetic martensitic transformation from paramagnetic (PM) austenite to FM martensite in the Ni- and Mn-substituted MnNiGe alloys with indium, a non-magnetic and large-sized main group element. Accordingly, a giant magnetocaloric effect such that a twofold increase of the magnetic entropy change in MnNi0.92GeIn0.08 and even a nearly threefold increase in the Mn0.92NiGeIn0.08 alloy is obtained with respect to the MnNiGe0.95In0.05 alloy. The origin of AFM-FM conversion and resultantly sharp magnetic-field-induced PM-FM metamagnetic transformation is discussed based on the first-principles calculations and X-ray absorption spectroscopic results.

A coordinated sequence of distinct flagellar waveforms enables a sharp flagellar turn mediated by squid sperm pH-taxis.

PubMed

Iida, Tomohiro; Iwata, Yoko; Mohri, Tatsuma; Baba, Shoji A; Hirohashi, Noritaka

2017-10-11

Animal spermatozoa navigate by sensing ambient chemicals to reach the site of fertilization. Generally, such chemicals derive from the female reproductive organs or cells. Exceptionally, squid spermatozoa mutually release and perceive carbon dioxide to form clusters after ejaculation. We previously identified the pH-taxis by which each spermatozoon can execute a sharp turn, but how flagellar dynamics enable this movement remains unknown. Here, we show that initiation of the turn motion requires a swim down a steep proton gradient (a theoretical estimation of ≥0.025 pH/s), crossing a threshold pH value of ~5.5. Time-resolved kinematic analysis revealed that the turn sequence results from the rhythmic exercise of two flagellar motions: a stereotypical flagellar 'bent-cane' shape followed by asymmetric wave propagation, which enables a sharp turn in the realm of low Reynolds numbers. This turning episode is terminated by an 'overshoot' trajectory that differs from either straight-line motility or turning. As with bidirectional pH-taxes in some bacteria, squid spermatozoa also showed repulsion from strong acid conditions with similar flagellar kinematics as in positive pH-taxis. These findings indicate that squid spermatozoa might have a unique reorientation mechanism, which could be dissimilar to that of classical egg-guided sperm chemotaxis in other marine invertebrates.

First reference curves of waist and hip circumferences in an Asian population of youths: CASPIAN study.

PubMed

Kelishadi, Roya; Gouya, Mohammad Mehdi; Ardalan, Gelayol; Hosseini, Mohsen; Motaghian, Molouk; Delavari, Alireza; Majdzadeh, Reza; Heidarzadeh, Abtin; Mahmoud-Arabi, Minou Sadat; Riazi, Mohammad Mehdi

2007-06-01

The Objective of the present study is to develop the first age- and gender-specific reference curves for waist and hip circumferences in an Asian population of youths. This cross-sectional population survey was conducted in 2003-04 on a nationally representative sample of 21111 school-students living in urban (84.6%) and rural (15.4%) areas of 23 provinces in Iran. After anthropometric measurements, smoothed reference curves for waist and hip circumference (WC, HiC) and waist-to-hip ratio (WHR) were developed by the LMS method. In both genders, WC and HiC percentile values increased with age. For girls, the 50th to 95th percentile curves for WC had a sharp increase between 8 and 13 years and 11-15 years, respectively, and began to plateau after this age, whereas for boys, these curves had a persistent and less sharp increase with age, until the age of 18 years. The WHR curves of girls decreased with age until 15 years and began to plateau thereafter, whereas for boys the 25th to 95th curves had a plateau pattern. Comparison of the current reference curves with the British ones showed that in boys, the 5th and 50th percentile curves were similar in both studies, but the 95th percentile curve of our study was higher than the British curves. For girls, the 5th percentile curves of both studies were similar, but the 50th and 95th percentile curves of our study were higher than the British ones. These curves represent the first childhood WC, HiC and WHR reference curves obtained in Asia. These curves can provide baseline data for analysis of time trends, as well as for international comparisons.

Strain-sensitive upconversion for imaging biological forces (Conference Presentation)

NASA Astrophysics Data System (ADS)

Lay, Alice; Wisser, Michael; Lin, Yu; Narayan, Tarun; Krieg, Michael; Atre, Ashwin; Goodman, Miriam; Dionne, Jennifer A.

2016-09-01

Nearly all diseases can be traced back to abnormal mechanotransduction, but few sensors can reliably measure biologically-relevant forces in vivo. Here, we investigate sub-25nm lanthanide-doped upconverting nanoparticles as novel optical force probes, which provide several biocompatible features: sharp emission peaks with near infrared illumination, a high signal-to-noise ratio, and photostability. To increase force sensitivity, we include d-metal doping in the nanoparticles; the d-metal siphons energy from the lanthanide ions with an efficiency that varies with pressure. We synthesize cubic-phase NaYF4: Er3+,Yb3+ nanoparticles doped with 0-5% Mn2+ and compress them in a hydrostatic environment using a diamond anvil cell. When illuminated at 980nm, the nanoparticles show sharp emission peaks centered at wavelengths of 522nm, 545nm, and 660nm. In 20nN increments, up to 700nN, the ratio of the red-to-green peaks in 0% Mn-doped nanoparticles increases by nearly 30%, resulting in a perceived color change from orange to red. In contrast, the 1% Mn-doped samples exhibit little color change but a large 40% decrease in upconversion intensity. In both cases, the red-to-green ratio varies linearly with strain and the optical properties are recoverable upon release. We further use atomic force microscopy to characterize optical responses at lower, pico-Newton to nano-Newton forces. To demonstrate in vivo imaging capabilities, we incubate C. elegans with nanoparticles dispersed in buffer solution (5mg/mL concentration) and image forces involved in digestion using confocal microscopy. Our nanoparticles provide a platform for the first, non-genetically-encoded in vivo force sensors, and we describe routes to increase their sensitivity to the single-pN range.

Notes on breeding sharp-shinned hawks and cooper’s hawks in Barnwell County, South Carolina

Treesearch

Mark Vukovich; John C. Kilgo

2009-01-01

Breeding records of Accipiter striatus (Sharp-shinned Hawks) in the southeastern US are scattered and isolated. We documented a Sharp-shinned Hawk and Accipiter cooperii (Cooper’s Hawk) nest while conducting a telemetry study on Melanerpes erythrocephalus (Red-headed Woodpeckers) in Barnwell County, SC in 2006 and 2007. We report the first known nest of a Sharp-shinned...

Edge Sharpness Assessment by Parametric Modeling: Application to Magnetic Resonance Imaging.

PubMed

Ahmad, R; Ding, Y; Simonetti, O P

2015-05-01

In biomedical imaging, edge sharpness is an important yet often overlooked image quality metric. In this work, a semi-automatic method to quantify edge sharpness in the presence of significant noise is presented with application to magnetic resonance imaging (MRI). The method is based on parametric modeling of image edges. First, an edge map is automatically generated and one or more edges-of-interest (EOI) are manually selected using graphical user interface. Multiple exclusion criteria are then enforced to eliminate edge pixels that are potentially not suitable for sharpness assessment. Second, at each pixel of the EOI, an image intensity profile is read along a small line segment that runs locally normal to the EOI. Third, the profiles corresponding to all EOI pixels are individually fitted with a sigmoid function characterized by four parameters, including one that represents edge sharpness. Last, the distribution of the sharpness parameter is used to quantify edge sharpness. For validation, the method is applied to simulated data as well as MRI data from both phantom imaging and cine imaging experiments. This method allows for fast, quantitative evaluation of edge sharpness even in images with poor signal-to-noise ratio. Although the utility of this method is demonstrated for MRI, it can be adapted for other medical imaging applications.

S-HARP: A parallel dynamic spectral partitioner

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sohn, A.; Simon, H.

1998-01-01

Computational science problems with adaptive meshes involve dynamic load balancing when implemented on parallel machines. This dynamic load balancing requires fast partitioning of computational meshes at run time. The authors present in this report a fast parallel dynamic partitioner, called S-HARP. The underlying principles of S-HARP are the fast feature of inertial partitioning and the quality feature of spectral partitioning. S-HARP partitions a graph from scratch, requiring no partition information from previous iterations. Two types of parallelism have been exploited in S-HARP, fine grain loop level parallelism and coarse grain recursive parallelism. The parallel partitioner has been implemented in Messagemore » Passing Interface on Cray T3E and IBM SP2 for portability. Experimental results indicate that S-HARP can partition a mesh of over 100,000 vertices into 256 partitions in 0.2 seconds on a 64 processor Cray T3E. S-HARP is much more scalable than other dynamic partitioners, giving over 15 fold speedup on 64 processors while ParaMeTiS1.0 gives a few fold speedup. Experimental results demonstrate that S-HARP is three to 10 times faster than the dynamic partitioners ParaMeTiS and Jostle on six computational meshes of size over 100,000 vertices.« less

Image Quality and Diagnostic Performance of a Digital PET Prototype in Patients with Oncologic Diseases: Initial Experience and Comparison with Analog PET.

PubMed

Nguyen, Nghi C; Vercher-Conejero, Jose L; Sattar, Abdus; Miller, Michael A; Maniawski, Piotr J; Jordan, David W; Muzic, Raymond F; Su, Kuan-Hao; O'Donnell, James K; Faulhaber, Peter F

2015-09-01

We report our initial clinical experience for image quality and diagnostic performance of a digital PET prototype scanner with time-of-flight (DigitalTF), compared with an analog PET scanner with time-of-flight (GeminiTF PET/CT). Twenty-one oncologic patients, mean age 58 y, first underwent clinical (18)F-FDG PET/CT on the GeminiTF. The scanner table was then withdrawn while the patient remained on the table, and the DigitalTF was inserted between the GeminiTF PET and CT scanner. The patients were scanned for a second time using the same PET field of view with CT from the GeminiTF for attenuation correction. Two interpreters reviewed the 2 sets of PET/CT images for overall image quality, lesion conspicuity, and sharpness. They counted the number of suggestive (18)F-FDG-avid lesions and provided the TNM staging for the 5 patients referred for initial staging. Standardized uptake values (SUVs) and SUV gradients as a measure of lesion sharpness were obtained. The DigitalTF showed better image quality than the GeminiTF. In a side-by-side comparison using a 5-point scale, lesion conspicuity (4.3 ± 0.6), lesion sharpness (4.3 ± 0.6), and diagnostic confidence (3.4 ± 0.7) were better with DigitalTF than with GeminiTF (P < 0.01). In 52 representative lesions, the lesion maximum SUV was 36% higher with DigitalTF than with GeminiTF, lesion-to-blood-pool SUV ratio was 59% higher, and SUV gradient was 51% higher, with good correlation between the 2 scanners. Lesions less than 1.5 cm showed a greater increase in SUV from GeminiTF to DigitalTF than those lesions 1.5 cm or greater. In 5 of 21 patients, DigitalTF showed an additional 8 suggestive lesions that were not seen using GeminiTF. In the 15 restaging patients, the true-negative rate was 100% and true-positive rate was 78% for both scanners. In the 5 patients for initial staging, DigitalTF led to upstaging in 2 patients and showed the same staging in the other 3 patients, compared with GeminiTF. DigitalTF provides better image quality, diagnostic confidence, and accuracy than GeminiTF. DigitalTF may be the most beneficial in detecting small tumor lesions and disease staging. © 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Magnetic Fano resonances by design in symmetry broken THz meta-foils

PubMed Central

Wu, Jianfeng; Moser, Herbert O.; Li, Rujiang; Yang, Yihao; Jing, Liqiao; Chen, Hongsheng; Breese, Mark B. H.

2017-01-01

Magnetic Fano resonances in there-dimensional symmetry broken meta-foils at THz frequencies are theoretically and experimentally studied. Sharp Fano resonances occur due to the interference between different resonances and can be designed by choosing geometric parameters of the meta-foil. At the Fano resonances, the meta-foil supports antisymmetric modes, whereas, at the main resonance, only a symmetric mode exists. The meta-foil is left-handed at the Fano resonances and shows sharp peaks of the real part of the refractive index in transmission with small effective losses opening a way to very sensitive high-speed sensing of dielectric changes in the surrounding media and of mechanical configuration. PMID:28150797

Sharp predictions from eternal inflation patches in D-brane inflation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hertog, Thomas; Janssen, Oliver, E-mail: thomas.hertog@fys.kuleuven.be, E-mail: opj202@nyu.edu

We numerically generate the six-dimensional landscape of D3-brane inflation and identify patches of eternal inflation near sufficiently flat inflection points of the potential. We show that reasonable measures that select patches of eternal inflation in the landscape yield sharp predictions for the spectral properties of primordial perturbations on observable scales. These include a scalar tilt of .936, a running of the scalar tilt −.00103, undetectably small tensors and non-Gaussianity, and no observable spatial curvature. Our results explicitly demonstrate that precision cosmology probes the combination of the statistical properties of the string landscape and the measure implied by the universe's quantummore » state.« less

Interictal Epileptiform Discharges (IEDs) classification in EEG data of epilepsy patients

NASA Astrophysics Data System (ADS)

Puspita, J. W.; Soemarno, G.; Jaya, A. I.; Soewono, E.

2017-12-01

Interictal Epileptiform Dischargers (IEDs), which consists of spike waves and sharp waves, in human electroencephalogram (EEG) are characteristic signatures of epilepsy. Spike waves are characterized by a pointed peak with a duration of 20-70 ms, while sharp waves has a duration of 70-200 ms. The purpose of the study was to classify spike wave and sharp wave of EEG data of epilepsy patients using Backpropagation Neural Network. The proposed method consists of two main stages: feature extraction stage and classification stage. In the feature extraction stage, we use frequency, amplitude and statistical feature, such as mean, standard deviation, and median, of each wave. The frequency values of the IEDs are very sensitive to the selection of the wave baseline. The selected baseline must contain all data of rising and falling slopes of the IEDs. Thus, we have a feature that is able to represent the type of IEDs, appropriately. The results show that the proposed method achieves the best classification results with the recognition rate of 93.75 % for binary sigmoid activation function and learning rate of 0.1.

DTK C/Fortran Interface Development for NEAMS FSI Simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Slattery, Stuart R.; Lebrun-Grandie, Damien T.

This report documents the development of DataTransferKit (DTK) C and Fortran interfaces for fluid-structure-interaction (FSI) simulations in NEAMS. In these simulations, the codes Nek5000 and Diablo are being coupled within the SHARP framework to study flow-induced vibration (FIV) in reactor steam generators. We will review the current Nek5000/Diablo coupling algorithm in SHARP and the current state of the solution transfer scheme used in this implementation. We will then present existing DTK algorithms which may be used instead to provide an improvement in both flexibility and scalability of the current SHARP implementation. We will show how these can be used withinmore » the current FSI scheme using a new set of interfaces to the algorithms developed by this work. These new interfaces currently expose the mesh-free solution transfer algorithms in DTK, a C++ library, and are written in C and Fortran to enable coupling of both Nek5000 and Diablo in their native Fortran language. They have been compiled and tested on Cooley, the test-bed machine for Mira at ALCF.« less

The split in the ancient cold front in the Perseus cluster

NASA Astrophysics Data System (ADS)

Walker, Stephen A.; ZuHone, John; Fabian, Andy; Sanders, Jeremy

2018-04-01

Sloshing cold fronts in clusters, produced as the dense cluster core moves around in the cluster potential in response to in-falling subgroups, provide a powerful probe of the physics of the intracluster medium and the magnetic fields permeating it1,2. These sharp discontinuities in density and temperature rise gradually outwards with age in a characteristic spiral pattern, embedding into the intracluster medium a record of the minor merging activity of clusters: the further from the cluster centre a cold front is, the older it is. Recently, it was discovered that these cold fronts can survive out to extremely large radii in the Perseus cluster3. Here, we report on high-spatial-resolution Chandra observations of the large-scale cold front in Perseus. We find that rather than broadening through diffusion, the cold front remains extremely sharp (consistent with abrupt jumps in density) and instead is split into two sharp edges. These results show that magnetic draping can suppress diffusion for vast periods of time—around 5 Gyr—even as the cold front expands out to nearly half the cluster virial radius.

Photon Counting Computed Tomography With Dedicated Sharp Convolution Kernels: Tapping the Potential of a New Technology for Stent Imaging.

PubMed

von Spiczak, Jochen; Mannil, Manoj; Peters, Benjamin; Hickethier, Tilman; Baer, Matthias; Henning, André; Schmidt, Bernhard; Flohr, Thomas; Manka, Robert; Maintz, David; Alkadhi, Hatem

2018-05-23

The aims of this study were to assess the value of a dedicated sharp convolution kernel for photon counting detector (PCD) computed tomography (CT) for coronary stent imaging and to evaluate to which extent iterative reconstructions can compensate for potential increases in image noise. For this in vitro study, a phantom simulating coronary artery stenting was prepared. Eighteen different coronary stents were expanded in plastic tubes of 3 mm diameter. Tubes were filled with diluted contrast agent, sealed, and immersed in oil calibrated to an attenuation of -100 HU simulating epicardial fat. The phantom was scanned in a modified second generation 128-slice dual-source CT scanner (SOMATOM Definition Flash, Siemens Healthcare, Erlangen, Germany) equipped with both a conventional energy integrating detector and PCD. Image data were acquired using the PCD part of the scanner with 48 × 0.25 mm slices, a tube voltage of 100 kVp, and tube current-time product of 100 mAs. Images were reconstructed using a conventional convolution kernel for stent imaging with filtered back-projection (B46) and with sinogram-affirmed iterative reconstruction (SAFIRE) at level 3 (I463). For comparison, a dedicated sharp convolution kernel with filtered back-projection (D70) and SAFIRE level 3 (Q703) and level 5 (Q705) was used. The D70 and Q70 kernels were specifically designed for coronary stent imaging with PCD CT by optimizing the image modulation transfer function and the separation of contrast edges. Two independent, blinded readers evaluated subjective image quality (Likert scale 0-3, where 3 = excellent), in-stent diameter difference, in-stent attenuation difference, mathematically defined image sharpness, and noise of each reconstruction. Interreader reliability was calculated using Goodman and Kruskal's γ and intraclass correlation coefficients (ICCs). Differences in image quality were evaluated using a Wilcoxon signed-rank test. Differences in in-stent diameter difference, in-stent attenuation difference, image sharpness, and image noise were tested using a paired-sample t test corrected for multiple comparisons. Interreader and intrareader reliability were excellent (γ = 0.953, ICCs = 0.891-0.999, and γ = 0.996, ICCs = 0.918-0.999, respectively). Reconstructions using the dedicated sharp convolution kernel yielded significantly better results regarding image quality (B46: 0.4 ± 0.5 vs D70: 2.9 ± 0.3; P < 0.001), in-stent diameter difference (1.5 ± 0.3 vs 1.0 ± 0.3 mm; P < 0.001), and image sharpness (728 ± 246 vs 2069 ± 411 CT numbers/voxel; P < 0.001). Regarding in-stent attenuation difference, no significant difference was observed between the 2 kernels (151 ± 76 vs 158 ± 92 CT numbers; P = 0.627). Noise was significantly higher in all sharp convolution kernel images but was reduced by 41% and 59% by applying SAFIRE levels 3 and 5, respectively (B46: 16 ± 1, D70: 111 ± 3, Q703: 65 ± 2, Q705: 46 ± 2 CT numbers; P < 0.001 for all comparisons). A dedicated sharp convolution kernel for PCD CT imaging of coronary stents yields superior qualitative and quantitative image characteristics compared with conventional reconstruction kernels. Resulting higher noise levels in sharp kernel PCD imaging can be partially compensated with iterative image reconstruction techniques.

Induction of the SHARP-2 mRNA level by insulin is mediated by multiple signaling pathways.

PubMed

Kanai, Yukiko; Asano, Kosuke; Komatsu, Yoshiko; Takagi, Katsuhiro; Ono, Moe; Tanaka, Takashi; Tomita, Koji; Haneishi, Ayumi; Tsukada, Akiko; Yamada, Kazuya

2017-02-01

The rat enhancer of split- and hairy-related protein-2 (SHARP-2) is an insulin-inducible transcription factor which represses transcription of the rat phosphoenolpyruvate carboxykinase gene. In this study, a regulatory mechanism of the SHARP-2 mRNA level by insulin was analyzed. Insulin rapidly induced the level of SHARP-2 mRNA. This induction was blocked by inhibitors for phosphoinositide 3-kinase (PI 3-K), protein kinase C (PKC), and mammalian target of rapamycin (mTOR), actinomycin D, and cycloheximide. Whereas an adenovirus infection expressing a dominant negative form of atypical PKC lambda (aPKCλ) blocked the insulin-induction of the SHARP-2 mRNA level, insulin rapidly activated the mTOR. Insulin did not enhance transcriptional activity from a 3.7 kb upstream region of the rat SHARP-2 gene. Thus, we conclude that insulin induces the expression of the rat SHARP-2 gene at the transcription level via both a PI 3-K/aPKCλ- and a PI 3-K/mTOR- pathways and that protein synthesis is required for this induction.

Audit of sharp weapon deaths in metropolis of Karachi--an autopsy based study.

PubMed

Mirza, Farhat Hussain; Hasan, Qudsia; Memon, Akhtar Amin; Adil, Syeda Ezz-e-Rukhshan

2010-01-01

Sharp weapons are one of the most violent and abhorrent means of deaths. This study assesses the frequency of sharp weapon deaths in Karachi. This was a cross sectional study, and involves the deaths by sharp weapons autopsied in Karachi during Mar 2008-Feb 2009. This study reports that the frequency of sharp weapon deaths in Karachi is similar to some other studies conducted in different regions of Pakistan, yet it is very high as the population of Karachi is way more than any other metropolis of Pakistan. Our study reported that out of 2090 medico-legal deaths in Karachi during the study period, 91 deaths were due to sharp weapons, including 73 (80.2%) males and 18 (19.8%) females. 100% of the deaths were homicides, so none were suicides. Deaths were more frequent in age group ranging from 20-39 years (59.3%). Sharp weapon deaths continue to be a means of quite a number of deaths in Karachi. Such violence depicts intolerant and frustrated nature of the citizens.

Standard Hardware Acquisition and Reliability Program's (SHARP's) efforts in incorporating fiber optic interconnects into standard electronic module (SEM) connectors

NASA Astrophysics Data System (ADS)

Riggs, William R.

1994-05-01

SHARP is a Navy wide logistics technology development effort aimed at reducing the acquisition costs, support costs, and risks of military electronic weapon systems while increasing the performance capability, reliability, maintainability, and readiness of these systems. Lower life cycle costs for electronic hardware are achieved through technology transition, standardization, and reliability enhancement to improve system affordability and availability as well as enhancing fleet modernization. Advanced technology is transferred into the fleet through hardware specifications for weapon system building blocks of standard electronic modules, standard power systems, and standard electronic systems. The product lines are all defined with respect to their size, weight, I/O, environmental performance, and operational performance. This method of defining the standard is very conducive to inserting new technologies into systems using the standard hardware. This is the approach taken thus far in inserting photonic technologies into SHARP hardware. All of the efforts have been related to module packaging; i.e. interconnects, component packaging, and module developments. Fiber optic interconnects are discussed in this paper.

Baroclinic mixing of potential vorticity as the principal sharpening mechanism for the extratropical Tropopause Inversion Layer

NASA Astrophysics Data System (ADS)

Wang, Shu Meir; Geller, Marvin A.

2016-09-01

Previous works have shown that a dry, idealized general circulation model could produce many features of the extratropical Tropopause Inversion Layer (TIL). In particular, the following have been shown, but no explanations were given for these results. (1) A sharper extratropical TIL resulted more from increased horizontal resolution than from increased vertical resolution. (2) If the Equator-to-Pole temperature gradient was varied, the annual variation of the extratropical TIL found in observations could be reproduced. (3) The extratropical TIL altitude showed excellent correlation with the upper tropospheric relative vorticity, as had been previously proposed. (4) Increased horizontal model resolutions led to extratropical TILs that were at lower altitudes. We show that these conclusions follow from baroclinic mixing of high stratospheric potential vorticity into the troposphere being the principal sharpening mechanism for the extratropical TIL and the increased baroclinic activity occurring in higher horizontal resolution models. We furthermore suggest that the distance from the jet exerts a greater influence on the height and sharpness of the extratropical TIL than does the upper tropospheric relative vorticity, and this accounts for the annual behavior of the extratropical TIL found in observations and reproduced with a dry, mechanistic, global model.

Pediatric foreign bodies and their management.

PubMed

Kay, Marsha; Wyllie, Robert

2005-06-01

Ingestion of foreign bodies is a common pediatric problem, with more than 100,000 cases occurring each year. The vast majority of pediatric ingestions are accidental; increasing incidence of intentional ingestions starts in the adolescent age group. In the United States, the most common pediatric foreign bodies ingested are coins, followed by a variety of other objects, including toys, toy parts, sharp objects, batteries, bones, and food. In adolescents and adults, meat or food impactions are the most common accidental foreign body ingestion. Esophageal pathology underlies most cases of food impaction. Management of foreign body ingestions varies based on the object ingested, its location, and the patient's age and size. Esophageal foreign bodies as a group require early intervention because of their potential to cause respiratory symptoms and complications, esophageal erosions, or even an aortoesophageal fistula. Ingested batteries that lodge in the esophagus require urgent endoscopic removal even in the asymptomatic patient due to the high risk of complications. Sharp foreign bodies increase the foreign body complication rate from less than 1% to 15% to 35%, except for straight pins, which usually follow a relatively benign course unless multiple pins are ingested. Magnets are increasingly ingested, due to their ubiquitous nature and the perception that they do not pose a risk. Ingestion of multiple magnets creates a significant risk of obstruction, perforation, and fistula development. Methods to deal with foreign bodies include the suture technique, the double snare technique, and the combined forceps/snare technique for long, large, and sharp foreign bodies, along with newer equipment, such as retrieval nets and a variety of specialized forceps.

Short- and Mid-Term Effects of Violent Victimization on Delinquency: A Multilevel Growth-Curve Modeling Approach.

PubMed

Kim, Young S; Lo, Celia C

2016-10-01

The present study investigates how adolescents' experiences of violent victimization exert short- and mid-term effects on their involvement in delinquency. The study compares and contrasts delinquency trajectories of youths whose experiences of violent victimization differ. A multilevel growth-curve modeling approach is applied to analyze data from five waves of the National Youth Survey. The results show that, although delinquency involvement increases as youths experience violent victimization, delinquency trajectories differ with the type of violent victimization, specifically, parental versus non-parental victimization. Violent victimization by parents produced a sharp initial decline in delinquency (short-term effect) followed by a rapid acceleration (mid-term effect). In turn, non-parental violence showed a stable trend over time. The findings have important implications for prevention and treatment services. © The Author(s) 2015.

Therapeutic index of gramicidin S is strongly modulated by D-phenylalanine analogues at the beta-turn.

PubMed

Solanas, Concepción; de la Torre, Beatriz G; Fernández-Reyes, María; Santiveri, Clara M; Jiménez, M Angeles; Rivas, Luis; Jiménez, Ana I; Andreu, David; Cativiela, Carlos

2009-02-12

Analogues of the cationic antimicrobial peptide gramicidin S (GS), cyclo(Val-Orn-Leu-D-Phe-Pro)2, with d-Phe residues replaced by different (restricted mobility, mostly) surrogates have been synthesized and used in SAR studies against several pathogenic bacteria. While all D-Phe substitutions are shown by NMR to preserve the overall beta-sheet conformation, they entail subtle structural alterations that lead to significant modifications in biological activity. In particular, the analogue incorporating D-Tic (1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid) shows a modest but significant increase in therapeutic index, mostly due to a sharp decrease in hemolytic effect. The fact that NMR data show a shortened distance between the D-Tic aromatic ring and the Orn delta-amino group may help explain the improved antibiotic profile of this analogue.

Therapeutic index of gramicidin S is strongly modulated by d-phenylalanine analogues at the β-turn

PubMed Central

Solanas, Concepción; de la Torre, Beatriz G.; Fernández-Reyes, María; Santiveri, Clara M.; Jiménez, M. Ángeles; Rivas, Luis; Jiménez, Ana I.; Andreu, David; Cativiela, Carlos

2009-01-01

Analogues of the cationic antimicrobial peptide gramicidin S (GS), cyclo(Val-Orn-Leu-d-Phe-Pro)2, with d-Phe residues replaced by different (restricted mobility, mostly) surrogates have been synthesized and used in SAR studies against several pathogenic bacteria. While all d-Phe substitutions are shown by NMR to preserve the overall β-sheet conformation, they entail subtle structural alterations that lead to significant modifications in biological activity. In particular, the analogue incorporating d-Tic (1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid) shows a modest but significant increase in therapeutic index, mostly due to a sharp decrease in hemolytic effect. The fact that NMR data show a shortened distance between the d-Tic aromatic ring and the Orn δ-amino group may help explain the improved antibiotic profile of this analogue. PMID:19132829

Transient enhancement of magnetization damping in CoFeB film via pulsed laser excitation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Bo; Ruan, Xuezhong, E-mail: xzruan@nju.edu.cn, E-mail: ybxu@nju.edu.cn; Wu, Zhenyao

2016-07-25

Laser-induced spin dynamics of in-plane magnetized CoFeB films has been studied by using time-resolved magneto-optical Kerr effect measurements. While the effective demagnetization field shows little dependence on the pump laser fluence, the intrinsic damping constant has been found to be increased from 0.008 to 0.076 with the increase in the pump fluence from 2 mJ/cm{sup 2} to 20 mJ/cm{sup 2}. This sharp enhancement has been shown to be transient and ascribed to the heating effect induced by the pump laser excitation, as the damping constant is almost unchanged when the pump-probe measurements are performed at a fixed pump fluence ofmore » 5 mJ/cm{sup 2} after irradiation by high power pump pulses.« less

Is public support for environmental protection decreasing? An analysis of U.S. and New Jersey data.

PubMed Central

Greenberg, Michael R

2004-01-01

Telephone surveys made of 800-1,000 randomly selected residents of the United States and New Jersey in 2003 show a sharp decline in support for antipollution regulations, although pollution remains a major concern. This drop in support is associated with slowing of the economy, fear of terrorism, and other competing priorities. The leading proponents of maintaining strong environmental regulations are relatively affluent mainstream white Americans. Despite this recent drop in support, overt attempts to weaken the basic regulations are likely to face stiff opposition unless there is an obvious economic downturn or increasing terrorism that causes a larger proportion of the public to feel that weakening environmental regulations will increase jobs and security. Key words: age, environmental laws and regulations, perception, polls, public support, race/ethnicity, trends. PMID:14754564

Extreme Lagrangian acceleration in confined turbulent flow.

PubMed

Kadoch, Benjamin; Bos, Wouter J T; Schneider, Kai

2008-05-09

A Lagrangian study of two-dimensional turbulence for two different geometries, a periodic and a confined circular geometry, is presented to investigate the influence of solid boundaries on the Lagrangian dynamics. It is found that the Lagrangian acceleration is even more intermittent in the confined domain than in the periodic domain. The flatness of the Lagrangian acceleration as a function of the radius shows that the influence of the wall on the Lagrangian dynamics becomes negligible in the center of the domain, and it also reveals that the wall is responsible for the increased intermittency. The transition in the Lagrangian statistics between this region, not directly influenced by the walls, and a critical radius which defines a Lagrangian boundary layer is shown to be very sharp with a sudden increase of the acceleration flatness from about 5 to about 20.

Orientation-dependent energy level alignment and film growth of 2,7-diocty[1]benzothieno[3,2-b]benzothiophene (C8-BTBT) on HOPG

NASA Astrophysics Data System (ADS)

Lyu, Lu; Niu, Dongmei; Xie, Haipeng; Cao, Ningtong; Zhang, Hong; Zhang, Yuhe; Liu, Peng; Gao, Yongli

2016-01-01

Combining ultraviolet photoemission spectroscopy, X-ray photoemission spectroscopy, atomic force microscopy, and X-ray diffraction measurements, we performed a systematic investigation on the correlation of energy level alignment, film growth, and molecular orientation of 2,7-diocty[1]benzothieno[3,2-b]benzothiophene (C8-BTBT) on highly oriented pyrolytic graphite. The molecules lie down in the first layer and then stand up from the second layer. The ionization potential shows a sharp decrease from the lying down region to the standing up region. When C8-BTBT molecules start standing up, unconventional energy level band-bending-like shifts are observed as the film thickness increases. These shifts are ascribed to gradual decreasing of the molecular tilt angle about the substrate normal with the increasing film thickness.

Orientation-dependent energy level alignment and film growth of 2,7-diocty[1]benzothieno[3,2-b]benzothiophene (C8-BTBT) on HOPG.

PubMed

Lyu, Lu; Niu, Dongmei; Xie, Haipeng; Cao, Ningtong; Zhang, Hong; Zhang, Yuhe; Liu, Peng; Gao, Yongli

2016-01-21

Combining ultraviolet photoemission spectroscopy, X-ray photoemission spectroscopy, atomic force microscopy, and X-ray diffraction measurements, we performed a systematic investigation on the correlation of energy level alignment, film growth, and molecular orientation of 2,7-diocty[1]benzothieno[3,2-b]benzothiophene (C8-BTBT) on highly oriented pyrolytic graphite. The molecules lie down in the first layer and then stand up from the second layer. The ionization potential shows a sharp decrease from the lying down region to the standing up region. When C8-BTBT molecules start standing up, unconventional energy level band-bending-like shifts are observed as the film thickness increases. These shifts are ascribed to gradual decreasing of the molecular tilt angle about the substrate normal with the increasing film thickness.

Metabolic adaptation and oxaloacetate homeostasis in P. fluorescens exposed to aluminum toxicity.

PubMed

Lemire, Joseph; Kumar, Puja; Mailloux, Ryan; Cossar, Kathyrn; Appanna, Vasu D

2008-08-01

Microbial systems are known to elaborate intricate metabolic strategies in an effort to fend the toxic impact of numerous metals. In this study, we show that the exposure of Pseudomonas fluorescens to aluminum (Al) resulted in a metabolic shift aimed at diverting oxaloacetate towards the biogenesis of an aluminophore. This metabolic alteration was characterized by uncoupling of two gluconeogenic enzymes, namely pyruvate carboxylase (PC) and phosphoenolpyruvate carboxykinase (PEPCK). While PC displayed a sharp increase in activity and expression, PEPCK was severely diminished. Malic enzyme (ME) and NAD kinase (NADK), two enzymes involved in maintaining a reductive environment, were markedly increased in the Al-stressed cells. Hence, Al-exposed Pseudomonas fluorescens evoked a metabolic response aimed at generating oxaloacetate and promoting an intracellular reductive environment. (c) 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Nucleation and Growth of Lithium Peroxide in the Li-O2 Battery.

PubMed

Lau, Sampson; Archer, Lynden A

2015-09-09

We study the relationship between Li2O2 morphology and the electrochemical performance of the Li-O2 battery using a combination of experiment and theory. Experimental Li-O2 battery discharge curves are accurately captured by a theoretical model in which electrode performance is limited by the nucleation and growth of discrete Li2O2 nanostructures in the cathode. We further show that the characteristic sharp voltage drop widely reported at the end of discharge results from the decrease in electrochemical surface area as Li2O2 covers the cathode surface. Preventing surface nucleation is highlighted as a core strategy for increasing Li-O2 battery capacity.

High temperature coercive field behavior of Fe-Zr powder

NASA Astrophysics Data System (ADS)

Mishra, Debabrata; Perumal, A.; Srinivasan, A.

2009-04-01

We report the investigation of high temperature coercive field behavior of Fe80Zr20 nanocrystalline alloy powder having two-phase microstructure prepared by mechanical alloying process. Thermomagnetization measurement shows the presence of two different magnetic phase transitions corresponding to the amorphous matrix and nonequilibrium Fe(Zr) solid solution. Temperature dependent coercivity exhibits a sharp increase in its value close to the Curie temperature of the amorphous matrix. This feature is attributed to the loss of intergranular ferromagnetic exchange coupling between the nanocrystallites due to the paramagnetic nature of the amorphous matrix. The temperature dependent coercive field behavior is ascribed to the variations in both the effective anisotropy and the exchange stiffness constant with temperature.

Application of aerial photography to the study of small scale upper ocean phenomena

NASA Technical Reports Server (NTRS)

Ichiye, T.; Carnes, M.

1981-01-01

The industrial waste dumped 180 n. miles south of Galveston was monitored in July 1977 by water sampling, hydrographic measurements, acoustic tracking on board two vessels, and by aerial photography. The plume of the waste diffused vertically and horizontally. Photodensitometry of aerial photos of the plume showed lateral dispersion of the plume in agreement with two other methods: acoustic tracking of the waste suspensoid and transmissometer sampling. In addition, the method showed small scale features like the lateral and longitudinal variations in the photodensity, indicating the waste concentration. This waste concentration showed periodic changes in its axial distance, with the spectral peak at about 160 m wave length. It shows a sharp increase at the windward edge of the plume as do the acoustic records. This phenomenon is explained in terms of the shearing current near the surface together with vertical diffusion. The periodic change along the axis is explained in terms of the Langmuir circulation and in terms of internal ship waves.

Electronic transport in armchair graphene nanoribbon under double magnetic barrier modulation

NASA Astrophysics Data System (ADS)

Wang, Haiyan; Wu, Chao; Xie, Fang; Zhang, Xiaojiao; Zhou, Guanghui

2018-03-01

We present a theoretical investigation of the transport properties and the magnetoresistance effect in armchair graphene nanoribbons (AGNRs) under modulation by two magnetic barriers. The energy levels are found to be degenerate for a metallic AGNR but are not degenerate for a semiconducting AGNR. However, the conductance characteristics show quantized plateaus in both the metallic and semiconducting cases. When the magnetization directions of the barriers change from parallel to antiparallel, the conductance plateau in the metallic AGNR shows a degenerate feature due to matching between the transport modes in different regions. As the barrier height increases, the conductance shows more oscillatory behavior with sharp peaks and troughs. Specifically, the initial position of nonzero conductance for the metallic AGNR system moves towards a higher energy regime, which indicates that an energy gap has been opened. In addition, the magnetoresistance ratio also shows plateau structures in certain specific energy regions. These results may be useful in the design of electron devices based on AGNR nanostructures.

Healthcare waste management practices and safety indicators in Nigeria.

PubMed

Oyekale, Abayomi Samuel; Oyekale, Tolulope Olayemi

2017-09-25

Adequate management of healthcare waste (HCW) is a prerequisite for efficient delivery of healthcare services. In Nigeria, there are several constraints militating against proper management of HCW. This is raising some environmental concerns among stakeholders in the health sector. In this study, we analyzed the practices of HCW management and determinants of risky/safe indices of HCW disposal. The study used the 2013/2014 Service Delivery Indicator (SDI) data that were collected from 2480 healthcare facilities in Nigeria. Descriptive statistics, Principal Component Analysis (PCA) and Ordinary Least Square (OLS) regression were used to analyze the data. The results showed that 52.20% and 38.21% of the sampled healthcare facilities from Cross River and Bauchi states possessed guidelines for HCW management, respectively. Trainings on management of HCW were attended by 67.18% and 53.19% of the healthcare facilities from Cross River and Imo states, respectively. Also, 32.32% and 29.50% of healthcare facilities from rural and urban areas previously sent some of their staff members for trainings on HCW management, respectively. Sharp and non-sharp HCW were burnt in protected pits in 45.40% and 45.36% of all the sampled healthcare facilities, respectively. Incinerators were reported to be functional in only 2.06% of the total healthcare facilities. In Bauchi and Kebbi states, 23.58% and 21.05% of the healthcare facilities respectively burnt sharp HCW without any protection. Using PCA, computed risky indices for disposal of sharp HCW were highest in Bayelsa state (0.3070) and Kebbi state (0.2172), while indices of risky disposal of non-sharp HCW were highest in Bayelsa state (0.2868) and Osun state (0.2652). The OLS results showed that at 5% level of significance, possession of medical waste disposal guidelines, staff trainings on HCW management, traveling hours from the facilities to local headquarters and being located in rural areas significantly influenced indices of risky/safe medical waste disposal (p < 0.05). The study concluded that there was low compliance with standard HCW management. It was recommended that possession of HCW management guidelines, staff training on HCW disposal and provision of requisite equipment for proper treatment of HCW would promote environmental safety in HCW disposal.

Application of the SHARP Toolkit to Sodium-Cooled Fast Reactor Challenge Problems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shemon, E. R.; Yu, Y.; Kim, T. K.

The Simulation-based High-efficiency Advanced Reactor Prototyping (SHARP) toolkit is under development by the Nuclear Energy Advanced Modeling and Simulation (NEAMS) Campaign of the U.S. Department of Energy, Office of Nuclear Energy. To better understand and exploit the benefits of advanced modeling simulations, the NEAMS Campaign initiated the “Sodium-Cooled Fast Reactor (SFR) Challenge Problems” task, which include the assessment of hot channel factors (HCFs) and the demonstration of zooming capability using the SHARP toolkit. If both challenge problems are resolved through advanced modeling and simulation using the SHARP toolkit, the economic competitiveness of a SFR can be significantly improved. The effortsmore » in the first year of this project focused on the development of computational models, meshes, and coupling procedures for multi-physics calculations using the neutronics (PROTEUS) and thermal-hydraulic (Nek5000) components of the SHARP toolkit, as well as demonstration of the HCF calculation capability for the 100 MWe Advanced Fast Reactor (AFR-100) design. Testing the feasibility of the SHARP zooming capability is planned in FY 2018. The HCFs developed for the earlier SFRs (FFTF, CRBR, and EBR-II) were reviewed, and a subset of these were identified as potential candidates for reduction or elimination through high-fidelity simulations. A one-way offline coupling method was used to evaluate the HCFs where the neutronics solver PROTEUS computes the power profile based on an assumed temperature, and the computational fluid dynamics solver Nek5000 evaluates the peak temperatures using the neutronics power profile. If the initial temperature profile used in the neutronics calculation is reasonably accurate, the one-way offline method is valid because the neutronics power profile has weak dependence on small temperature variation. In order to get more precise results, the proper temperature profile for initial neutronics calculations was obtained from the STAR-CCM+ calculations. The HCFs of the peak temperatures at cladding outer surface, cladding inner wall surface, and fuel centerline induced by cladding manufacturing tolerance and uncertainties on the cladding, coolant, and fuel properties were evaluated for the AFR-100. Some assessment on the effect of wire wrap configuration and size of the bundle shows that it is practical to use the 7-pin bare rod bundle to calculate the HCFs. The resulting HCFs obtained from the high-fidelity SHARP calculations are generally smaller than those developed for the earlier SFRs because the most uncertainties involved in the modeling and simulations were disappeared. For completeness, additional investigations are planned in FY 2018, which will use random sampling techniques.« less

Sumoylation of the Basic Helix-Loop-Helix Transcription Factor Sharp-1 Regulates Recruitment of the Histone Methyltransferase G9a and Function in Myogenesis*

PubMed Central

Wang, Yaju; Shankar, Shilpa Rani; Kher, Devaki; Ling, Belinda Mei Tze; Taneja, Reshma

2013-01-01

Sumoylation is an important post-translational modification that alters the activity of many transcription factors. However, the mechanisms that link sumoylation to alterations in chromatin structure, which culminate in tissue specific gene expression, are not fully understood. In this study, we demonstrate that SUMO modification of the transcription factor Sharp-1 is required for its full transcriptional repression activity and function as an inhibitor of skeletal muscle differentiation. Sharp-1 is modified by sumoylation at two conserved lysine residues 240 and 255. Mutation of these SUMO acceptor sites in Sharp-1 does not impact its subcellular localization but attenuates its ability to act as a transcriptional repressor and inhibit myogenic differentiation. Consistently, co-expression of the SUMO protease SENP1 with wild type Sharp-1 abrogates Sharp-1-dependent inhibition of myogenesis. Interestingly, sumoylation acts as a signal for recruitment of the co-repressor G9a. Thus, enrichment of G9a, and histone H3 lysine 9 dimethylation (H3K9me2), a signature of G9a activity, is dramatically reduced at muscle promoters in cells expressing sumoylation-defective Sharp-1. Our findings demonstrate how sumoylation of Sharp-1 exerts an impact on chromatin structure and transcriptional repression of muscle gene expression through recruitment of G9a. PMID:23637228

Heaven Knows I'm Miserable Now: Overeducation and Reduced Life Satisfaction

ERIC Educational Resources Information Center

Piper, Alan

2015-01-01

Recently the supply of young graduates entering the UK labour market has undergone a sharp increase. A possible consequence of this is an increase in the number of individuals who are overeducated for the jobs that they do subsequent to participating in higher education. Using British panel data and dynamic panel analysis, I demonstrate that…

Evaluating Academic Development in the Higher Education Sector: Academic Developers' Reflections on Using a Toolkit Resource

ERIC Educational Resources Information Center

Winter, Jennie; Turner, Rebecca; Spowart, Lucy; Muneer, Reema; Kneale, Pauline

2017-01-01

The professionalisation of teaching is of increasing importance in UK higher education due to converging processes including the proliferation of managerialism, increasing quality agendas and changes to student fee structures. These have brought into sharp relief the need for greater understanding of how quality teaching evolves in university…

Sharp-tailed Grouse Restoration; Colville Tribes Restore Habitat for Sharp-tailed Grouse, Annual Report 2002-2003.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whitney, Richard

2004-01-01

Columbian Sharp-Tailed Grouse (Tympanuchus phasianellus columbianus) (CSTG) are an important traditional and cultural species to the Colville Confederated Tribes (CCT), Spokane Tribe of Indians (STOI), and other Tribes in the Region. They were once the most abundant upland bird in the Region. Currently, the largest remaining population in Washington State occurs on the CCT Reservation in Okanogan County. Increasing agricultural practices and other land uses has contributed to the decline of sharp-tail habitat and populations putting this species at risk. The decline of this species is not new (Yokum, 1952, Buss and Dziedzic, 1955, Zeigler, 1979, Meints 1991, and Crawfordmore » and Snyder 1994). The Tribes (CCT and STOI) are determined to protect, enhance and restore habitat for this species continued existence. When Grand Coulee and Chief Joseph Hydro-projects were constructed, inundated habitat used by this species was lost forever adding to overall decline. To compensate and prevent further habitat loss, the CCT proposed a project with Bonneville Power Administration (BPA) funding to address this species and their habitat requirements. The projects main focus is to address habitat utilized by the current CSTG population and determine ways to protect, restore, and enhance habitats for the conservation of this species over time. The project went through the NPPC Review Process and was funded through FY03 by BPA. This report addresses part of the current CCT effort to address the conservation of this species on the Colville Reservation.« less

Confirmation of the Factor Structure and Measurement Invariance of the Children's Scale of Hostility and Aggression: Reactive/Proactive in Clinic-Referred Children With and Without Autism Spectrum Disorder.

PubMed

Farmer, Cristan A; Kaat, Aaron J; Mazurek, Micah O; Lainhart, Janet E; DeWitt, Mary Beth; Cook, Edwin H; Butter, Eric M; Aman, Michael G

2016-02-01

The measurement of aggression in its different forms (e.g., physical and verbal) and functions (e.g., impulsive and instrumental) is given little attention in subjects with developmental disabilities (DD). In this study, we confirm the factor structure of the Children's Scale for Hostility and Aggression: Reactive/Proactive (C-SHARP) and demonstrate measurement invariance (consistent performance across clinical groups) between clinic-referred groups with and without autism spectrum disorder (ASD). We also provide evidence of the construct validity of the C-SHARP. Caregivers provided C-SHARP, Child Behavior Checklist (CBCL), and Proactive/Reactive Rating Scale (PRRS) ratings for 644 children, adolescents, and young adults 2-21 years of age. Five types of measurement invariance were evaluated within a confirmatory factor analytic framework. Associations among the C-SHARP, CBCL, and PRRS were explored. The factor structure of the C-SHARP had a good fit to the data from both groups, and strict measurement invariance between ASD and non-ASD groups was demonstrated (i.e., equivalent structure, factor loadings, item intercepts and residuals, and latent variance/covariance between groups). The C-SHARP Problem Scale was more strongly associated with CBCL Externalizing than with CBCL Internalizing, supporting its construct validity. Subjects classified with the PRRS as both Reactive and Proactive had significantly higher C-SHARP Proactive Scores than those classified as Reactive only, who were rated significantly higher than those classified by the PRRS as Neither Reactive nor Proactive. A similar pattern was observed for the C-SHARP Reactive Score. This study provided evidence of the validity of the C-SHARP through confirmation of its factor structure and its relationship with more established scales. The demonstration of measurement invariance demonstrates that differences in C-SHARP factor scores were the result of differences in the construct rather than to error or unmeasured/nuisance variables. These data suggest that the C-SHARP is useful for quantifying subtypes of aggressive behavior in children, adolescents, and young adults with DD.

Diffusion sampler testing at Naval Air Station North Island, San Diego County, California, November 1999 to January 2000

USGS Publications Warehouse

Vroblesky, Don A.; Peters, Brian C.

2000-01-01

Volatile organic compound concentrations in water from diffusion samplers were compared to concentrations in water obtained by low-flow purging at 15 observation wells at the Naval Air Station North Island, San Diego, California. Multiple diffusion samplers were installed in the wells. In general, comparisons using bladder pumps and diffusion samplers showed similar volatile organic carbon concentrations. In some wells, sharp concentration gradients were observed, such as an increase in cis-1,2-dichloroethene concentration from 100 to 2,600 micrograms per liter over a vertical distance of only 3.4 feet. In areas where such sharp gradients were observed, concentrations in water obtained by low-flow sampling at times reflected an average concentration over the area of influence; however, concentrations obtained by using the diffusion sampler seemed to represent the immediate vicinity of the sampler. When peristaltic pumps were used to collect ground-water samples by low-flow purging, the volatile organic compound concentrations commonly were lower than concentrations obtained by using diffusion samplers. This difference may be due to loss of volatiles by degassing under negative pressures in the sampling lines induced while using the peristaltic pump, mixing in the well screen, or possible short-circuiting of water from an adjacent depth. Diffusion samplers placed in buckets of freephase jet fuel (JP-5) and Stoddard solvent from observation wells did not show evidence of structural integrity loss during the 2 months of equilibration, and volatile organic compounds detected in the free-phase fuel also were detected in the water from the diffusion samplers.

Hybrid Image Fusion for Sharpness Enhancement of Multi-Spectral Lunar Images

NASA Astrophysics Data System (ADS)

Awumah, Anna; Mahanti, Prasun; Robinson, Mark

2016-10-01

Image fusion enhances the sharpness of a multi-spectral (MS) image by incorporating spatial details from a higher-resolution panchromatic (Pan) image [1,2]. Known applications of image fusion for planetary images are rare, although image fusion is well-known for its applications to Earth-based remote sensing. In a recent work [3], six different image fusion algorithms were implemented and their performances were verified with images from the Lunar Reconnaissance Orbiter (LRO) Camera. The image fusion procedure obtained a high-resolution multi-spectral (HRMS) product from the LRO Narrow Angle Camera (used as Pan) and LRO Wide Angle Camera (used as MS) images. The results showed that the Intensity-Hue-Saturation (IHS) algorithm results in a high-spatial quality product while the Wavelet-based image fusion algorithm best preserves spectral quality among all the algorithms. In this work we show the results of a hybrid IHS-Wavelet image fusion algorithm when applied to LROC MS images. The hybrid method provides the best HRMS product - both in terms of spatial resolution and preservation of spectral details. Results from hybrid image fusion can enable new science and increase the science return from existing LROC images.[1] Pohl, Cle, and John L. Van Genderen. "Review article multisensor image fusion in remote sensing: concepts, methods and applications." International journal of remote sensing 19.5 (1998): 823-854.[2] Zhang, Yun. "Understanding image fusion." Photogramm. Eng. Remote Sens 70.6 (2004): 657-661.[3] Mahanti, Prasun et al. "Enhancement of spatial resolution of the LROC Wide Angle Camera images." Archives, XXIII ISPRS Congress Archives (2016).

Resource scarcity drives lethal aggression among prehistoric hunter-gatherers in central California.

PubMed

Allen, Mark W; Bettinger, Robert Lawrence; Codding, Brian F; Jones, Terry L; Schwitalla, Al W

2016-10-25

The origin of human violence and warfare is controversial, and some scholars contend that intergroup conflict was rare until the emergence of sedentary foraging and complex sociopolitical organization, whereas others assert that violence was common and of considerable antiquity among small-scale societies. Here we consider two alternative explanations for the evolution of human violence: (i) individuals resort to violence when benefits outweigh potential costs, which is likely in resource poor environments, or (ii) participation in violence increases when there is coercion from leaders in complex societies leading to group level benefits. To test these hypotheses, we evaluate the relative importance of resource scarcity vs. sociopolitical complexity by evaluating spatial variation in three macro datasets from central California: (i) an extensive bioarchaeological record dating from 1,530 to 230 cal BP recording rates of blunt and sharp force skeletal trauma on thousands of burials, (ii) quantitative scores of sociopolitical complexity recorded ethnographically, and (iii) mean net primary productivity (NPP) from a remotely sensed global dataset. Results reveal that sharp force trauma, the most common form of violence in the record, is better predicted by resource scarcity than relative sociopolitical complexity. Blunt force cranial trauma shows no correlation with NPP or political complexity and may reflect a different form of close contact violence. This study provides no support for the position that violence originated with the development of more complex hunter-gatherer adaptations in the fairly recent past. Instead, findings show that individuals are prone to violence in times and places of resource scarcity.

The Sharpness of Blades Used in Dermatologic Surgery.

PubMed

Awadalla, Farah; Hexsel, Camile; Goldberg, Leonard H

2016-01-01

There are numerous blades available for use in dermatologic procedures. There are different advantages that are inhere.nt to different blades due to their shape and size. One aspect of the blade that is instrumental to its performance, but is not objectively defined, is sharpness. This information could be useful when choosing a blade for a particular procedure. This study aims to objectively define the sharpness of blades used in dermatologic surgery. The Sharpness Tester (Cutlery and Allied Trades Research Association, Sheffield, UK) was used to test the force in Newtons a blade requires to cut through a silicone cylinder. New blades were used to determine a standard for the sharpness of new blades. Blades used for surgery were tested to determine the sharpness after use. The sharpest blade is the double-edged razor blade (0.395 N) followed by the dermablade (0.46 N), plastic handled #15 (0.541 N), #15c (0.575 N), #10 (0.647 N), and the #15 blade (0.664 N). The sharpness of a blade is an important factor in its ability to perform a task and should be taken into account when choosing a particular blade for a particular procedure.

Selection of UV Resins for Nanostructured Molds for Thermal-NIL.

PubMed

Jia, Zheng; Choi, Junseo; Park, Sunggook

2018-06-18

Nanoimprint molds made of soft polymeric materials have advantages of low demolding force and low fabrication cost over Si or metal-based hard molds. However, such advantages are often sacrificed by their reduced replication fidelity associated with the low mechanical strength. In this paper, we studied replication fidelity of different UV-resin molds copied from a Si master mold via UV nanoimprint lithography (NIL) and their thermal imprinting performance into a thermoplastic polymer. Four different UV resins were studied: two were high surface energy UV resins based on tripropyleneglycol diacrylate (TPGDA resin) and polypropyleneglycol diacrylate (PPGDA resin), and the other two were commercially available, low surface energy poly-urethane acrylate (PUA resin) and fluorine-containing (MD 700) UV resins. The replication fidelity among the four UV-resins during UV nanoimprint lithograph from a Si master with sharp nanostructures was in the increasing order of (poorest) PUA resin < MD 700 < PPGDA resin < TPGDA resin (best). The results show that the high surface energy and small monomer size are keys to achieving good UV resin filling into sharp nanostructures over the viscosity of the resin solution. When the four UV-resin molds were used for thermal-NIL into a thermoplastic polymer, the replication fidelity was in the increasing order of (poorest) MD 700 < TPGDA resin < PUA resin (best), which follows the same order of their Young's moduli. Our results indicate that the selection of an appropriate UV resin for NIL molds requires consideration of the replication fidelities in the mold fabrication and the subsequent thermal-NIL into thermoplastic polymers. © 2018 IOP Publishing Ltd.

The Hayflick Limit May Determine the Effective Clonal Diversity of Naive T Cells.

PubMed

Ndifon, Wilfred; Dushoff, Jonathan

2016-06-15

Having a large number of sufficiently abundant T cell clones is important for adequate protection against diseases. However, as shown in this paper and elsewhere, between young adulthood and >70 y of age the effective clonal diversity of naive CD4/CD8 T cells found in human blood declines by a factor of >10. (Effective clonal diversity accounts for both the number and the abundance of T cell clones.) The causes of this observation are incompletely understood. A previous study proposed that it might result from the emergence of certain rare, replication-enhancing mutations in T cells. In this paper, we propose an even simpler explanation: that it results from the loss of T cells that have attained replicative senescence (i.e., the Hayflick limit). Stochastic numerical simulations of naive T cell population dynamics, based on experimental parameters, show that the rate of homeostatic T cell proliferation increases after the age of ∼60 y because naive T cells collectively approach replicative senescence. This leads to a sharp decline of effective clonal diversity after ∼70 y, in agreement with empirical data. A mathematical analysis predicts that, without an increase in the naive T cell proliferation rate, this decline will occur >50 yr later than empirically observed. These results are consistent with a model in which exhaustion of the proliferative capacity of naive T cells causes a sharp decline of their effective clonal diversity and imply that therapeutic potentiation of thymopoiesis might either prevent or reverse this outcome. Copyright © 2016 by The American Association of Immunologists, Inc.

Dual Energy CT (DECT) Monochromatic Imaging: Added Value of Adaptive Statistical Iterative Reconstructions (ASIR) in Portal Venography.

PubMed

Zhao, Liqin; Winklhofer, Sebastian; Jiang, Rong; Wang, Xinlian; He, Wen

2016-01-01

To investigate the effect of the adaptive statistical iterative reconstructions (ASIR) on image quality in portal venography by dual energy CT (DECT) imaging. DECT scans of 45 cirrhotic patients obtained in the portal venous phase were analyzed. Monochromatic images at 70keV were reconstructed with the following 4 ASIR percentages: 0%, 30%, 50%, and 70%. The image noise (IN) (standard deviation, SD) of portal vein (PV), the contrast-to-noise-ratio (CNR), and the subjective score for the sharpness of PV boundaries, and the diagnostic acceptability (DA) were obtained. The IN, CNR, and the subjective scores were compared among the four ASIR groups. The IN (in HU) of PV (10.05±3.14, 9.23±3.05, 8.44±2.95 and 7.83±2.90) decreased and CNR values of PV (8.04±3.32, 8.95±3.63, 9.80±4.12 and 10.74±4.73) increased with the increase in ASIR percentage (0%, 30%, 50%, and 70%, respectively), and were statistically different for the 4 ASIR groups (p<0.05). The subjective scores showed that the sharpness of portal vein boundaries (3.13±0.59, 2.82±0.44, 2.73±0.54 and 2.07±0.54) decreased with higher ASIR percentages (p<0.05). The subjective diagnostic acceptability was highest at 30% ASIR (p<0.05). 30% ASIR addition in DECT portal venography could improve the 70 keV monochromatic image quality.

Dual Energy CT (DECT) Monochromatic Imaging: Added Value of Adaptive Statistical Iterative Reconstructions (ASIR) in Portal Venography

PubMed Central

Winklhofer, Sebastian; Jiang, Rong; Wang, Xinlian; He, Wen

2016-01-01

Objective To investigate the effect of the adaptive statistical iterative reconstructions (ASIR) on image quality in portal venography by dual energy CT (DECT) imaging. Materials and Methods DECT scans of 45 cirrhotic patients obtained in the portal venous phase were analyzed. Monochromatic images at 70keV were reconstructed with the following 4 ASIR percentages: 0%, 30%, 50%, and 70%. The image noise (IN) (standard deviation, SD) of portal vein (PV), the contrast-to-noise-ratio (CNR), and the subjective score for the sharpness of PV boundaries, and the diagnostic acceptability (DA) were obtained. The IN, CNR, and the subjective scores were compared among the four ASIR groups. Results The IN (in HU) of PV (10.05±3.14, 9.23±3.05, 8.44±2.95 and 7.83±2.90) decreased and CNR values of PV (8.04±3.32, 8.95±3.63, 9.80±4.12 and 10.74±4.73) increased with the increase in ASIR percentage (0%, 30%, 50%, and 70%, respectively), and were statistically different for the 4 ASIR groups (p<0.05). The subjective scores showed that the sharpness of portal vein boundaries (3.13±0.59, 2.82±0.44, 2.73±0.54 and 2.07±0.54) decreased with higher ASIR percentages (p<0.05). The subjective diagnostic acceptability was highest at 30% ASIR (p<0.05). Conclusions 30% ASIR addition in DECT portal venography could improve the 70 keV monochromatic image quality. PMID:27315158

Rethinking the role of worry in generalized anxiety disorder: evidence supporting a model of emotional contrast avoidance.

PubMed

Llera, Sandra J; Newman, Michelle G

2014-05-01

The Contrast Avoidance model (Newman & Llera, 2011) proposes that individuals with generalized anxiety disorder (GAD) are hypersensitive to sharp upward shifts in negative emotion that typically accompany negative events, and use worry to maintain sustained intrapersonal negativity in an attempt to avoid these shifts. Although research shows that worry increases negative emotionality and mutes further emotional reactivity to a stressor when compared to the worry period (e.g., Llera & Newman, 2010), no study has tracked changes in negative emotionality from baseline to worry inductions followed by a range of emotional exposures. Further, no study has yet assessed participants' subjective appraisals of prior worry on helping to cope with such exposures. The present study tested the main tenets of the Contrast Avoidance model by randomly assigning participants with GAD (n=48) and nonanxious controls (n=47) to experience worry, relaxation, and neutral inductions prior to sequential exposure to fearful, sad, and humorous film clips. Both physiological (nonspecific skin conductance responses [NS-SCRs]) and self-reported emotional changes were observed. Results indicated that worry boosted negative emotionality from baseline, which was sustained across negative exposures, whereas low negative emotionality during relaxation and neutral inductions allowed for sharp increases in response to exposures. Furthermore, GAD participants found worry to be more helpful than other conditions in coping with exposures, whereas control participants reported the opposite pattern. Results provide preliminary support for the Contrast Avoidance model. This suggests that treatment should focus on underlying avoidance patterns before attempting to reduce worry behavior. Copyright © 2014. Published by Elsevier Ltd.

Malnutrition, a Global Problem

USDA-ARS?s Scientific Manuscript database

Malnutrition is a general term for medical conditions caused by an inadequate diet and poor nutrition. Hunger and malnutrition are among the major difficulties confronting many countries around the world. Malnutrition can be caused by several factors, such as the sharp increase in population (curren...

Rising breakeven load factors threaten airline finances

DOT National Transportation Integrated Search

2003-10-01

Since 2000, most large passenger airlines suffered a sharp increase in their Breakeven Load Factor the number of seats they have to sell to cover operating expenses. Some carriers could not cover operating expenses even if they sold 100% of their...

High-angular-resolution NIR astronomy with large arrays (SHARP I and SHARP II)

NASA Astrophysics Data System (ADS)

Hofmann, Reiner; Brandl, Bernhard; Eckart, Andreas; Eisenhauer, Frank; Tacconi-Garman, Lowell E.

1995-06-01

SHARP I and SHARP II are near infrared cameras for high-angular-resolution imaging. Both cameras are built around a 256 X 256 pixel NICMOS 3 HgCdTe array from Rockwell which is sensitive in the 1 - 2.5 micrometers range. With a 0.05'/pixel scale, they can produce diffraction limited K-band images at 4-m-class telescopes. For a 256 X 256 array, this pixel scale results in a field of view of 12.8' X 12.8' which is well suited for the observation of galactic and extragalactic near-infrared sources. Photometric and low resolution spectroscopic capabilities are added by photometric band filters (J, H, K), narrow band filters ((lambda) /(Delta) (lambda) approximately equals 100) for selected spectral lines, and a CVF ((lambda) /(Delta) (lambda) approximately equals 70). A cold shutter permits short exposure times down to about 10 ms. The data acquisition electronics permanently accepts the maximum frame rate of 8 Hz which is defined by the detector time constants (data rate 1 Mbyte/s). SHARP I has been especially designed for speckle observations at ESO's 3.5 m New Technology Telescope and is in operation since 1991. SHARP II is used at ESO's 3.6 m telescope together with the adaptive optics system COME-ON + since 1993. A new version of SHARP II is presently under test, which incorporates exchangeable camera optics for observations with scales of 0.035, 0.05, and 0.1'/pixel. The first scale extends diffraction limited observations down to the J-band, while the last one provides a larger field of view. To demonstrate the power of the cameras, images of the galactic center obtained with SHARP I, and images of the R136 region in 30 Doradus observed with SHARP II are presented.

The risk of capsular breakage from phacoemulsification needle contact with the lens capsule: a laboratory study.

PubMed

Meyer, Jay J; Kuo, Annie F; Olson, Randall J

2010-06-01

To determine capsular breakage risk from contact by phacoemulsification needles by machine and tip type. Experimental laboratory investigation. Infiniti (Alcon, Inc.) with Intrepid cartridges and Signature (Abbott Medical Optics, Inc.) phacoemulsification machines were tested using 19- and 20-gauge sharp and rounded tips. Actual and unoccluded flow vacuum were determined at 550 mm Hg, bottle height of 75 cm, and machine-indicated flow rate of 60 mL/minute. Breakage from brief tip contact with a capsular surrogate and human cadaveric lenses was calculated. Nineteen-gauge tips had more flow and less unoccluded flow vacuum than 20-gauge tips for both machines, with highest unoccluded flow vacuum in the Infiniti. The 19-gauge sharp tip was more likely than the 20-gauge sharp tip to cause surrogate breakage for Signature with micropulse and Ellips (Abbott Medical Optics, Inc.) ultrasound at 100% power. For Infiniti using OZil (Alcon, Inc.) ultrasound, 20-gauge sharp tips were more likely than 19-gauge sharp tips to break the membrane. For cadaveric lenses, using rounded 20-gauge tips at 100% power, breakage rates were micropulse (2.3%), Ellips (2.3%), OZil (5.3%). Breakage rates for sharp 20-gauge Ellips tips were higher than for rounded tips. Factors influencing capsular breakage may include active vacuum at the tip, flow rate, needle gauge, and sharpness. Nineteen-gauge sharp tips were more likely than 20-gauge tips to cause breakage in lower vacuum methods. For higher-vacuum methods, breakage is more likely with 20-gauge than with 19-gauge tips. Rounded-edge tips are less likely than sharp-edged tips to cause breakage. Copyright 2010 Elsevier Inc. All rights reserved.

SHARP Multiphysics Tutorials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yu, Y. Q.; Shemon, E. R.; Mahadevan, Vijay S.

SHARP, developed under the NEAMS Reactor Product Line, is an advanced modeling and simulation toolkit for the analysis of advanced nuclear reactors. SHARP is comprised of three physics modules currently including neutronics, thermal hydraulics, and structural mechanics. SHARP empowers designers to produce accurate results for modeling physical phenomena that have been identified as important for nuclear reactor analysis. SHARP can use existing physics codes and take advantage of existing infrastructure capabilities in the MOAB framework and the coupling driver/solver library, the Coupled Physics Environment (CouPE), which utilizes the widely used, scalable PETSc library. This report aims at identifying the coupled-physicsmore » simulation capability of SHARP by introducing the demonstration example called sahex in advance of the SHARP release expected by Mar 2016. sahex consists of 6 fuel pins with cladding, 1 control rod, sodium coolant and an outer duct wall that encloses all the other components. This example is carefully chosen to demonstrate the proof of concept for solving more complex demonstration examples such as EBR II assembly and ABTR full core. The workflow of preparing the input files, running the case and analyzing the results is demonstrated in this report. Moreover, an extension of the sahex model called sahex_core, which adds six homogenized neighboring assemblies to the full heterogeneous sahex model, is presented to test homogenization capabilities in both Nek5000 and PROTEUS. Some primary information on the configuration and build aspects for the SHARP toolkit, which includes capability to auto-download dependencies and configure/install with optimal flags in an architecture-aware fashion, is also covered by this report. A step-by-step instruction is provided to help users to create their cases. Details on these processes will be provided in the SHARP user manual that will accompany the first release.« less

NASA-Ames Summer High School Apprenticeship Research Program (SHARP)

NASA Technical Reports Server (NTRS)

Powell, P.

1983-01-01

The function of SHARP is to recognize high school juniors who have demonstrated unusually high promise for sucess in mathemtics and science. Twenty academically talented students who will be seniors in high school in September were chosen to participate in SHARP 83. Mentors were selected to provide students with first-hand experiences in a research and development environment in order that each student might try out his or her tentative professional career choice. Some special features of SHARP included field trips to private industries doing similar and related research, special lectures on topics of research here at ARC, individual and group counseling sessions, written research papers and oral reports, and primarily the opportunity to be exposed to the present frontiers in space exploration and research. The long-range goal of SHARP is to contribute to the future recruitment of needed scientists and engineers. This final report is summary of all the phases of the planning and implemenation of the 1983 Summer High School Apprenticeship Research Program (SHARP).

Weapon Use in Korean Homicide: Differences Between Homicides Involving Sharp and Blunt Instruments.

PubMed

Park, Jisun; Son, Hyeonseo

2017-10-23

On the basis of information regarding 276 homicides committed in South Korea between 1987 and 2008, we compared offenders' and victims' characteristics, injury locations, weapon-related behavior, and offending behavior between homicides involving sharp and blunt instruments. The victims of sharp-force homicide were much younger relative to those of blunt-force homicide. In addition, homicides involving blunt instruments were more likely to be committed by offenders who lived with the victims. Most sharp-force homicides involved injuries to the torso, while blunt-force homicides involved mainly head injuries. Furthermore, perpetrators of sharp-force homicides tended to preselect their weapons, while those of blunt-force homicides were likely to use weapons of opportunity. Logistic regression analysis identified a number of factors, including injury location and body transportation, which significantly predicted weapon type. As this was the first South Korean study to compare sharp- and blunt-force homicides, the results have practical implications for homicide investigations. © 2017 American Academy of Forensic Sciences.

The 1985 pittsburgh conference: a special instrumentation report.

PubMed

1985-03-29

For the first time in its 36 years of operation, the Pittsburgh Conference and Exposition on Analytical Chemistry and Applied Spectroscopy had a sharp drop in attendance-down 16 percent to 20,731. That loss was attributed to the fact that the meeting was held in New Orleans for the first time, and most of the lost attendees were students and young professionals who had previously come for only 1 day. The number of exhibitors and the number of booths, however, were both up about 15 percent, to 730 and 1856, respectively. A large proportion of that increase was contributed by foreign companies exhibiting for the first time, but there were also some well-known names, such as General Electric and Xerox, making first forays into analytical chemistry. There was also a sharp increase in the number and type of instruments displayed. "The key skill now in analytical chemistry," says Perkin-Elmer president Horace McDonell, Jr., "may be simply finding the right tool to obtain the answers you need." The predominant theme of the show, as it has been for the past few years, was automation of both laboratories and instruments. That trend is having major effects in chemical laboratories, but it is also affecting the instrument companies themselves. At large companies such as Varian, Beckman, and Perkin-Elmer, as much as 50 percent of the research and development budget is now going toward development of software-a much higher percentage than it was even 5 years ago. Another trend in automation also seemed clear at the show. As recently as 2 or 3 years ago, much of the available software for chemistry was designed for Apple and similar computers. Now, the laboratory standard is the IBM PC. As a representative of another company that manufactures computers noted with only slight exaggeration, "There's probably not a booth on the floor that doesn't have one."

Wild monkeys flake stone tools.

PubMed

Proffitt, Tomos; Luncz, Lydia V; Falótico, Tiago; Ottoni, Eduardo B; de la Torre, Ignacio; Haslam, Michael

2016-11-03

Our understanding of the emergence of technology shapes how we view the origins of humanity. Sharp-edged stone flakes, struck from larger cores, are the primary evidence for the earliest stone technology. Here we show that wild bearded capuchin monkeys (Sapajus libidinosus) in Brazil deliberately break stones, unintentionally producing recurrent, conchoidally fractured, sharp-edged flakes and cores that have the characteristics and morphology of intentionally produced hominin tools. The production of archaeologically visible cores and flakes is therefore no longer unique to the human lineage, providing a comparative perspective on the emergence of lithic technology. This discovery adds an additional dimension to interpretations of the human Palaeolithic record, the possible function of early stone tools, and the cognitive requirements for the emergence of stone flaking.

Causes of Cracking of Ignition Cable

NASA Technical Reports Server (NTRS)

Silsbee, F B

1921-01-01

The experiments described here show that the cracking at sharp bends, observed in the insulation of internal combustion engine high tension ignition wires after service, is due to a chemical attack upon the rubber by the ozone produced by the electric discharge that takes place at the surface of the cable. This cracking does not occur if the insulating material is not under tension, or if the cable is surrounded by some medium other than air. But it does occur even if the insulation is not subjected to electric stress, provided that the atmosphere near the cable contains ozone. The extent of this cracking varies greatly with the insulating material used. The cracking can be materially reduced by using braided cable and by avoiding sharp bends.

Real time algorithms for sharp wave ripple detection.

PubMed

Sethi, Ankit; Kemere, Caleb

2014-01-01

Neural activity during sharp wave ripples (SWR), short bursts of co-ordinated oscillatory activity in the CA1 region of the rodent hippocampus, is implicated in a variety of memory functions from consolidation to recall. Detection of these events in an algorithmic framework, has thus far relied on simple thresholding techniques with heuristically derived parameters. This study is an investigation into testing and improving the current methods for detection of SWR events in neural recordings. We propose and profile methods to reduce latency in ripple detection. Proposed algorithms are tested on simulated ripple data. The findings show that simple realtime algorithms can improve upon existing power thresholding methods and can detect ripple activity with latencies in the range of 10-20 ms.

Cross-Bedding at Whale Rock

NASA Image and Video Library

2014-12-08

This view from the NASA Curiosity Mars rover shows an example of cross-bedding that results from water passing over a loose bed of sediment. It was taken at a target called Whale Rock within the Pahrump Hills outcrop at the base of Mount Sharp.

Hippocampal Sharp Wave Bursts Coincide with Neocortical "Up-State" Transitions

ERIC Educational Resources Information Center

Battaglia, Francesco P.; Sutherland, Gary R.; McNaughton, Bruce L.

2004-01-01

The sleeping neocortex shows nested oscillatory activity in different frequency ranges, characterized by fluctuations between "up-states" and "down-states." High-density neuronal ensemble recordings in rats now reveal the interaction between synchronized activity in the hippocampus and neocortex: Electroencephalographic sharp…

The disengagement of visual attention in the gap paradigm across adolescence.

PubMed

Van der Stigchel, S; Hessels, R S; van Elst, J C; Kemner, C

2017-12-01

Attentional disengagement is important for successful interaction with our environment. The efficiency of attentional disengagement is commonly assessed using the gap paradigm. There is, however, a sharp contrast between the number of studies applying the gap paradigm to clinical populations and the knowledge about the underlying developmental trajectory of the gap effect. The aim of the present study was, therefore, to investigate attentional disengagement in a group of children aged 9-15. Besides the typically deployed gap and the overlap conditions, we also added a baseline condition in which the fixation point was removed at the moment that the target appeared. This allowed us to reveal the appropriate experimental conditions to unravel possible developmental differences. Correlational analyses showed that the size of the gap effect became smaller with increasing age, but only for the difference between the gap and the overlap conditions. This shows that there is a gradual increase in the capacity to disengage visual attention with increasing age, but that this effect only becomes apparent when the gap and the overlap conditions are compared. The gradual decrease of the gap effect with increasing age provides additional evidence that the attentional system becomes more efficient with increasing age and that this is a gradual process.

Historical and Projected Surface Temperature over India during the 20th and 21st century.

PubMed

Basha, Ghouse; Kishore, P; Ratnam, M Venkat; Jayaraman, A; Agha Kouchak, Amir; Ouarda, Taha B M J; Velicogna, Isabella

2017-06-07

Surface Temperature (ST) over India has increased by ~0.055 K/decade during 1860-2005 and follows the global warming trend. Here, the natural and external forcings (e.g., natural and anthropogenic) responsible for ST variability are studied from Coupled Model Inter-comparison phase 5 (CMIP5) models during the 20 th century and projections during the 21 st century along with seasonal variability. Greenhouse Gases (GHG) and Land Use (LU) are the major factors that gave rise to warming during the 20 th century. Anthropogenic Aerosols (AA) have slowed down the warming rate. The CMIP5 projection over India shows a sharp increase in ST under Representative Concentration Pathways (RCP) 8.5 where it reaches a maximum of 5 K by the end of the 21 st century. Under RCP2.6 emission scenarios, ST increases up to the year 2050 and decreases afterwards. The seasonal variability of ST during the 21 st century shows significant increase during summer. Analysis of rare heat and cold events for 2080-2099 relative to a base period of 1986-2006 under RCP8.5 scenarios reveals that both are likely to increase substantially. However, by controlling the regional AA and LU change in India, a reduction in further warming over India region might be achieved.

Single-event effects experienced by astronauts and microelectronic circuits flown in space

DOE Office of Scientific and Technical Information (OSTI.GOV)

McNulty, P.J.

Models developed for explaining the light flashes experienced by astronauts on Apollo and Skylab missions were used with slight modification to explain upsets observed in microelectronic circuits. Both phenomena can be explained by the simple assumption that an event occurs whenever a threshold number of ionizations or isomerizations are generated within a sensitive volume. Evidence is consistent with the threshold being sharp in both cases, but fluctuations in the physical stimuli lead to a gradual rather than sharp increase in cross section with LET. Successful use of the model requires knowledge of the dimensions of the sensitive volume and themore » value of threshold. Techniques have been developed to determine these SEU parameters in modern circuits.« less

Klein tunneling in the α -T3 model

NASA Astrophysics Data System (ADS)

Illes, E.; Nicol, E. J.

2017-06-01

We investigate Klein tunneling for the α -T3 model, which interpolates between graphene and the dice lattice via parameter α . We study transmission across two types of electrostatic interfaces: sharp potential steps and sharp potential barriers. We find both interfaces to be perfectly transparent for normal incidence for the full range of the parameter α for both interfaces. For other angles of incidence, we find that transmission is enhanced with increasing α . For the dice lattice, we find perfect, all-angle transmission across a potential step for incoming electrons with energy equal to half of the height of the potential step. This is analogous to the "super", all-angle transmission reported for the dice lattice for Klein tunneling across a potential barrier.

Analogue modelling of thrust systems: Passive vs. active hanging wall strain accommodation and sharp vs. smooth fault-ramp geometries

NASA Astrophysics Data System (ADS)

Rosas, F. M.; Duarte, J. C.; Almeida, P.; Schellart, W. P.; Riel, N.; Terrinha, P.

2017-06-01

We present new analogue modelling results of crustal thrust-systems in which a deformable (brittle) hanging wall is assumed to endure passive internal deformation during thrusting, i.e. exclusively as a consequence of having to adapt its shape to the variable geometry of a rigid footwall. Building on previous experimental contributions, we specifically investigate the role of two so far overlooked critical variables: a) concave-convex (CC) vs. flat-ramp-flat (FRF) thrust ramp geometry; and b) presence vs. absence of a basal velocity discontinuity (VD). Regarding the first variable, we compare new results for considered (CC) smoother ramp types against classical experiments in which (FRF) sharp ramp geometries are always prescribed. Our results show that the considered sharp vs. smooth variation in the thrust-ramp geometry produces important differences in the distribution of the local stress field in the deformable hanging wall above both (lower and upper) fault bends, with corresponding styles of strain accommodation being expressed by marked differences in measured morpho-structural parameters. Regarding the second variable, we for the first time report analogue modelling results of this type of experiments in which basal VDs are experimentally prescribed to be absent. Our results critically show that true passive hanging wall deformation is only possible to simulate in the absence of any basal VD, since active shortening accommodation always necessarily occurs in the hanging wall above such a discontinuity (i.e. above the lower fault bend). In addition, we show that the morpho-structural configuration of model thrust-wedges formed for prescribed VD absence conditions complies well with natural examples of major overthrusts, wherein conditions must occur that approximate a frictionless state along the main basal thrust-plane.

DRINKING WATER FROM AGRICULTURALLY CONTAMINATED GROUNDWATER

EPA Science Inventory

Sharp increases in fertilizer and pesticide use throughout the 1960s and 1970s along with generally less attachment to soil particles may result in more widespread contamination of drinking water supplies. he purpose of this study was to highlight the use of agricultural chemical...

A NASA SHARP Mentoring Experience Utilizing GP-B

NASA Technical Reports Server (NTRS)

Estes, Howard

2004-01-01

The goal of this program is to increase the participation and success rates of students who are traditionally underrepresented in science, mathematics, technology , and geography. Students are selected based on aptitude and oi nterests. It is a NASA sponsored, 8 week program.

The Provision and Completion of Gender-Specific Services for Girls on Probation: Variation by Race and Ethnicity

ERIC Educational Resources Information Center

Wolf, Angela M.; Graziano, Juliette; Hartney, Christopher

2009-01-01

Beginning in the late 1980s, the number of girls entering the juvenile justice system increased dramatically. Although historically girls had entered the justice system with status offenses, recent examinations suggest a sharp rise in the number of girls charged with more serious crimes. Researchers and policy makers have increasingly acknowledged…

Sticker Shock: State Funding Cuts Lead to Sharp Tuition Hikes at Florida Colleges

ERIC Educational Resources Information Center

Boulard, Garry

2011-01-01

The tuition increase at the University of Florida--one of 11 public universities in Florida to win the approval of the state's Board of Governors to tack a "tuition differential" of 7 percent onto an 8 percent increase already approved by the state legislature--comes in response to an unprecedented reduction of some $340 million in state…

Biodiversity response to natural gradients of multiple stressors on continental margins

PubMed Central

Sperling, Erik A.; Frieder, Christina A.; Levin, Lisa A.

2016-01-01

Sharp increases in atmospheric CO2 are resulting in ocean warming, acidification and deoxygenation that threaten marine organisms on continental margins and their ecological functions and resulting ecosystem services. The relative influence of these stressors on biodiversity remains unclear, as well as the threshold levels for change and when secondary stressors become important. One strategy to interpret adaptation potential and predict future faunal change is to examine ecological shifts along natural gradients in the modern ocean. Here, we assess the explanatory power of temperature, oxygen and the carbonate system for macrofaunal diversity and evenness along continental upwelling margins using variance partitioning techniques. Oxygen levels have the strongest explanatory capacity for variation in species diversity. Sharp drops in diversity are seen as O2 levels decline through the 0.5–0.15 ml l−1 (approx. 22–6 µM; approx. 21–5 matm) range, and as temperature increases through the 7–10°C range. pCO2 is the best explanatory variable in the Arabian Sea, but explains little of the variance in diversity in the eastern Pacific Ocean. By contrast, very little variation in evenness is explained by these three global change variables. The identification of sharp thresholds in ecological response are used here to predict areas of the seafloor where diversity is most at risk to future marine global change, noting that the existence of clear regional differences cautions against applying global thresholds. PMID:27122565

Limnological and fishery studies on Lake Sharpe, a main-stem Missouri River reservoir

USGS Publications Warehouse

June, Fred C.; Beckman, L.G.; Elrod, J.H.; O'Bryan, G.K.; Vogel, D.A.

1987-01-01

Lake Sharpe, the most recent of six main-stem Missouri River reservoirs to be impounded, began to fill in November 1963 and became fully operational in July 1966. At full pool it is 137 km long, and has a surface area of 22,600 ha and a volume of 2.34 km". It is operated as a flow-through power generation system that reregulates discharges from upstream Lake Oahe. Major changes in the water-management regimen during 1966-75 were increased summer discharges beginning in 1969 and increased peaking operations beginning in 1973. Lake Sharpe had a relatively short aging process because it filled rapidly, the water level remained relatively stable, and the waterexchange rate was high. Consequently, most physical, chemical, and biological characteristics were remarkably uniform during 1966–75. The temperature regimen was largely governed by inflow from Lake Oahe. Although the water mass warmed during summer, thermal stratification was generally transient, limited to the lower reservoir, and more common during periods of relatively low discharge rates in 1966–68 than in later years. Variation in turbidity was striking; the midsection of the reservoir was generally most turbid. Chemical ion composition of the water tended to be uniform; observed differences were localized and associated with tributary inflows. Phytoplankton abundance reached its highest levels during 1970–75. Composition of the zooplankton community changed during 1966–75; the abundance of cyclopoid copepods decreased and that of calanoid copepods and cladocerans increased. Total abundance varied during the 10-year period, but without apparent trend. Variation in abundance appeared to be associated with discharge rate, water temperature, and turbidity. The benthic community in 1967-68 consisted mostly of chironomid larvae, which were uniformly distributed over the length of the reservoir.

The Helioseismic and Magnetic Imager (HMI) Vector Magnetic Field Pipeline: SHARPs - Space-Weather HMI Active Region Patches

NASA Astrophysics Data System (ADS)

Bobra, M. G.; Sun, X.; Hoeksema, J. T.; Turmon, M.; Liu, Y.; Hayashi, K.; Barnes, G.; Leka, K. D.

2014-09-01

A new data product from the Helioseismic and Magnetic Imager (HMI) onboard the Solar Dynamics Observatory (SDO) called Space-weather HMI Active Region Patches ( SHARPs) is now available. SDO/HMI is the first space-based instrument to map the full-disk photospheric vector magnetic field with high cadence and continuity. The SHARP data series provide maps in patches that encompass automatically tracked magnetic concentrations for their entire lifetime; map quantities include the photospheric vector magnetic field and its uncertainty, along with Doppler velocity, continuum intensity, and line-of-sight magnetic field. Furthermore, keywords in the SHARP data series provide several parameters that concisely characterize the magnetic-field distribution and its deviation from a potential-field configuration. These indices may be useful for active-region event forecasting and for identifying regions of interest. The indices are calculated per patch and are available on a twelve-minute cadence. Quick-look data are available within approximately three hours of observation; definitive science products are produced approximately five weeks later. SHARP data are available at jsoc.stanford.edu and maps are available in either of two different coordinate systems. This article describes the SHARP data products and presents examples of SHARP data and parameters.

Inhibiting the oxidation of diamond during preparing the vitrified dental grinding tools by depositing a ZnO coating using direct urea precipitation method.

PubMed

Wang, Yanhui; Yuan, Yungang; Cheng, Xiaozhe; Li, Xiaohu; Zang, Jianbing; Lu, Jing; Yu, Yiqing; Xu, Xipeng

2015-08-01

Oxidation of diamond during the manufacturing of vitrified dental grinding tools would reduce the strength and sharpness of tools. Zinc oxide (ZnO) coating was deposited on diamond particles by urea precipitation method to protect diamond in borosilicate glass. The FESEM results showed that the ZnO coating was formed by plate-shaped particles. According to the TG results, the onset oxidation temperature of the ZnO-coated diamond was about 70 °C higher than the pristine diamond. The EDS results showed that ZnO diffused into the borosilicate glass during sintering. As the result, the bending strength of the composites containing ZnO-coated diamond was increased by 24% compared to that of the composites containing pristine diamond. Copyright © 2015 Elsevier B.V. All rights reserved.

Monte Carlo simulation of hard spheres near random closest packing using spherical boundary conditions

NASA Astrophysics Data System (ADS)

Tobochnik, Jan; Chapin, Phillip M.

1988-05-01

Monte Carlo simulations were performed for hard disks on the surface of an ordinary sphere and hard spheres on the surface of a four-dimensional hypersphere. Starting from the low density fluid the density was increased to obtain metastable amorphous states at densities higher than previously achieved. Above the freezing density the inverse pressure decreases linearly with density, reaching zero at packing fractions equal to 68% for hard spheres and 84% for hard disks. Using these new estimates for random closest packing and coefficients from the virial series we obtain an equation of state which fits all the data up to random closest packing. Usually, the radial distribution function showed the typical split second peak characteristic of amorphous solids and glasses. High density systems which lacked this split second peak and showed other sharp peaks were interpreted as signaling the onset of crystal nucleation.

Looking sharp: Becoming a search template boosts precision and stability in visual working memory.

PubMed

Rajsic, Jason; Ouslis, Natasha E; Wilson, Daryl E; Pratt, Jay

2017-08-01

Visual working memory (VWM) plays a central role in visual cognition, and current work suggests that there is a special state in VWM for items that are the goal of visual searches. However, whether the quality of memory for target templates differs from memory for other items in VWM is currently unknown. In this study, we measured the precision and stability of memory for search templates and accessory items to determine whether search templates receive representational priority in VWM. Memory for search templates exhibited increased precision and probability of recall, whereas accessory items were remembered less often. Additionally, while memory for Templates showed benefits when instances of the Template appeared in search, this benefit was not consistently observed for Accessory items when they appeared in search. Our results show that becoming a search template can substantially affect the quality of a representation in VWM.

Investigation on the Interface Morphologies of Explosive Welding of Inconel 625 to Steel A516 Plates

NASA Astrophysics Data System (ADS)

Mousavi, S. A. A. Akbari; Zareie, H. R.

2011-01-01

The purpose of this study is to produce composite plates by explosive cladding process. This is a process in which the controlled energy of explosives is used to create a metallic bond between two similar or dissimilar materials. The welding conditions were tailored through parallel geometry route with different operational parameters. In this investigation, a two-pronged study was adopted to establish the conditions required for producing successful solid state welding: (a) Analytical calculations to determine the weldability domain or welding window; (b) Metallurgical investigations of explosive welding experiments carried out under different explosive ratios to produce both wavy and straight interfaces. The analytical calculations confirm the experimental results. Optical microscopy studies show that a transition from a smooth to wavy interface occurs with an increase in explosive ratio. SEM studies show that the interface was outlined by characteristic sharp transition between two materials.

Fluid-Dynamic Properties of Some Simple Sharp- and Blunt-Nosed Shapes at Mach Numbers from 16 to 24 in Helium Flow

NASA Technical Reports Server (NTRS)

Henderson, Arthur, Jr.; Johnston, Patrick J.

1959-01-01

The fluid-dynamic characteristics of flat plates, 5 deg and 10 deg wedges, and 5 deg and 10 deg cones have been investigated at Mach numbers from 16.3 to 23.9 in helium flow. The flat-plate results are for a leading-edge Reynolds number range of 584 to 19,500 and show that the induced pressure distribution is essentially linear with the hypersonic viscous interaction parameter bar X within the scope of this investigation. It is also shown that the rate at which the induced pressure varies with bar X is a linear function of the leading-edge Reynolds number. The wedge and cone results show that as the flow-deflection angle increases, the induced-pressure effects decrease and the measured pressures approach those predicted by inviscid shock theory.

Evolution and control of the phase competition morphology in a manganite film

NASA Astrophysics Data System (ADS)

Zhou, Haibiao; Wang, Lingfei; Hou, Yubin; Huang, Zhen; Lu, Qingyou; Wu, Wenbin

2015-11-01

The competition among different phases in perovskite manganites is pronounced since their energies are very close under the interplay of charge, spin, orbital and lattice degrees of freedom. To reveal the roles of underlying interactions, many efforts have been devoted towards directly imaging phase transitions at microscopic scales. Here we show images of the charge-ordered insulator (COI) phase transition from a pure ferromagnetic metal with reducing field or increasing temperature in a strained phase-separated manganite film, using a home-built magnetic force microscope. Compared with the COI melting transition, this reverse transition is sharp, cooperative and martensitic-like with astonishingly unique yet diverse morphologies. The COI domains show variable-dimensional growth at different temperatures and their distribution can illustrate the delicate balance of the underlying interactions in manganites. Our findings also display how phase domain engineering is possible and how the phase competition can be tuned in a controllable manner.

Evolution and control of the phase competition morphology in a manganite film.

PubMed

Zhou, Haibiao; Wang, Lingfei; Hou, Yubin; Huang, Zhen; Lu, Qingyou; Wu, Wenbin

2015-11-25

The competition among different phases in perovskite manganites is pronounced since their energies are very close under the interplay of charge, spin, orbital and lattice degrees of freedom. To reveal the roles of underlying interactions, many efforts have been devoted towards directly imaging phase transitions at microscopic scales. Here we show images of the charge-ordered insulator (COI) phase transition from a pure ferromagnetic metal with reducing field or increasing temperature in a strained phase-separated manganite film, using a home-built magnetic force microscope. Compared with the COI melting transition, this reverse transition is sharp, cooperative and martensitic-like with astonishingly unique yet diverse morphologies. The COI domains show variable-dimensional growth at different temperatures and their distribution can illustrate the delicate balance of the underlying interactions in manganites. Our findings also display how phase domain engineering is possible and how the phase competition can be tuned in a controllable manner.

Spatially discrete thermal drawing of biodegradable microneedles for vascular drug delivery.

PubMed

Choi, Chang Kuk; Lee, Kang Ju; Youn, Young Nam; Jang, Eui Hwa; Kim, Woong; Min, Byung-Kwon; Ryu, WonHyoung

2013-02-01

Spatially discrete thermal drawing is introduced as a novel method for the fabrication of biodegradable microneedles with ultra-sharp tip ends. This method provides the enhanced control of microneedle shapes by spatially controlling the temperature of drawn polymer as well as drawing steps and speeds. Particular focus is given on the formation of sharp tip ends of microneedles at the end of thermal drawing. Previous works relied on the fracture of polymer neck by fast drawing that often causes uncontrolled shapes of microneedle tips. Instead, this approach utilizes the surface energy of heated polymer to form ultra-sharp tip ends. We have investigated the effect of such temperature control, drawing speed, and drawing steps in thermal drawing process on the final shape of microneedles using biodegradable polymers. XRD analysis was performed to analyze the effect of thermal cycle on the biodegradable polymer. Load-displacement measurement also showed the dependency of mechanical strengths of microneedles on the microneedle shapes. Ex vivo vascular tissue insertion and drug delivery demonstrated microneedle insertion to tunica media layer of canine aorta and drug distribution in the tissue layer. Copyright © 2012 Elsevier B.V. All rights reserved.

Retinal image quality assessment based on image clarity and content

NASA Astrophysics Data System (ADS)

Abdel-Hamid, Lamiaa; El-Rafei, Ahmed; El-Ramly, Salwa; Michelson, Georg; Hornegger, Joachim

2016-09-01

Retinal image quality assessment (RIQA) is an essential step in automated screening systems to avoid misdiagnosis caused by processing poor quality retinal images. A no-reference transform-based RIQA algorithm is introduced that assesses images based on five clarity and content quality issues: sharpness, illumination, homogeneity, field definition, and content. Transform-based RIQA algorithms have the advantage of considering retinal structures while being computationally inexpensive. Wavelet-based features are proposed to evaluate the sharpness and overall illumination of the images. A retinal saturation channel is designed and used along with wavelet-based features for homogeneity assessment. The presented sharpness and illumination features are utilized to assure adequate field definition, whereas color information is used to exclude nonretinal images. Several publicly available datasets of varying quality grades are utilized to evaluate the feature sets resulting in area under the receiver operating characteristic curve above 0.99 for each of the individual feature sets. The overall quality is assessed by a classifier that uses the collective features as an input vector. The classification results show superior performance of the algorithm in comparison to other methods from literature. Moreover, the algorithm addresses efficiently and comprehensively various quality issues and is suitable for automatic screening systems.

Psychometric properties of the Children's Scale of Hostility and Aggression: Reactive/Proactive (C-SHARP).

PubMed

Farmer, Cristan A; Aman, Michael G

2010-01-01

Although often lacking "malice", aggression is fairly common in children with intellectual or developmental disability (I/DD). Despite this, there are no scales available that are appropriate for an in-depth analysis of aggressive behavior in this population. Such scales are needed for the study of aggressive behavior, which is a common target symptom in clinical trials. We assessed the reliability and validity of the Children's Scale of Hostility and Aggression: Reactive/Proactive (C-SHARP), a new aggression scale created for children with I/DD. Data are presented from a survey of 365 children with I/DD aged 3-21 years. Interrater reliability was very high for the Problem Scale, which characterizes type of aggression. Reliability was lower but largely acceptable for the Provocation Scale, which assesses motivation. Validity of the Problem Scale was supported by expected differences in children with autism, Down syndrome, comorbid disruptive behavior disorders (DBDs) and ADHD. The Provocation Scale, which categorizes behavior as proactive or reactive, showed expected differences in children with DBD, but was less effective in those with ADHD. The C-SHARP appears to have fundamentally sound psychometric characteristics, although more research is needed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hasegawa, Tomo; Shahed, Syed Mohammad Fakruddin; Sainoo, Yasuyuki

We formed an epitaxial film of CeO{sub 2}(111) by sublimating Ce atoms on Ru(0001) surface kept at elevated temperature in an oxygen ambient. X-ray photoemission spectroscopy measurement revealed a decrease of Ce{sup 4+}/Ce{sup 3+} ratio in a small temperature window of the growth temperature between 1070 and 1096 K, which corresponds to the reduction of the CeO{sub 2}(111). Scanning tunneling microscope image showed that a film with a wide terrace and a sharp step edge was obtained when the film was grown at the temperatures close to the reduction temperature, and the terrace width observed on the sample grown atmore » 1060 K was more than twice of that grown at 1040 K. On the surface grown above the reduction temperature, the surface with a wide terrace and a sharp step was confirmed, but small dots were also seen in the terrace part, which are considerably Ce atoms adsorbed at the oxygen vacancies on the reduced surface. This experiment demonstrated that it is required to use the substrate temperature close to the reduction temperature to obtain CeO{sub 2}(111) with wide terrace width and sharp step edges.« less

Deciphering the role of CA1 inhibitory circuits in sharp wave-ripple complexes.

PubMed

Cutsuridis, Vassilis; Taxidis, Jiannis

2013-01-01

Sharp wave-ripples (SWRs) are population oscillatory patterns in hippocampal LFPs during deep sleep and immobility, involved in the replay of memories acquired during wakefulness. SWRs have been extensively studied, but their exact generation mechanism is still unknown. A computational model has suggested that fast perisomatic inhibition may generate the high frequency ripples (~200 Hz). Another model showed how replay of memories can be controlled by various classes of inhibitory interneurons targeting specific parts of pyramidal cells (PC) and firing at particular SWR phases. Optogenetic studies revealed new roles for interneuronal classes and rich dynamic interplays between them, shedding new light in their potential role in SWRs. Here, we integrate these findings in a conceptual model of how dendritic and somatic inhibition may collectively contribute to the SWR generation. We suggest that sharp wave excitation and basket cell (BC) recurrent inhibition synchronises BC spiking in ripple frequencies. This rhythm is imposed on bistratified cells which prevent pyramidal bursting. Axo-axonic and stratum lacunosum/moleculare interneurons are silenced by inhibitory inputs originating in the medial septum. PCs receiving rippling inhibition in both dendritic and perisomatic areas and excitation in their apical dendrites, exhibit sparse ripple phase-locked spiking.

Designing a stable feedback control system for blind image deconvolution.

PubMed

Cheng, Shichao; Liu, Risheng; Fan, Xin; Luo, Zhongxuan

2018-05-01

Blind image deconvolution is one of the main low-level vision problems with wide applications. Many previous works manually design regularization to simultaneously estimate the latent sharp image and the blur kernel under maximum a posterior framework. However, it has been demonstrated that such joint estimation strategies may lead to the undesired trivial solution. In this paper, we present a novel perspective, using a stable feedback control system, to simulate the latent sharp image propagation. The controller of our system consists of regularization and guidance, which decide the sparsity and sharp features of latent image, respectively. Furthermore, the formational model of blind image is introduced into the feedback process to avoid the image restoration deviating from the stable point. The stability analysis of the system indicates the latent image propagation in blind deconvolution task can be efficiently estimated and controlled by cues and priors. Thus the kernel estimation used for image restoration becomes more precision. Experimental results show that our system is effective on image propagation, and can perform favorably against the state-of-the-art blind image deconvolution methods on different benchmark image sets and special blurred images. Copyright © 2018 Elsevier Ltd. All rights reserved.

[Study of enzymes of xenobiotic metabolism in the evaluation of quality of protein-containing wheat germ flakes and wallpaper flour].

PubMed

Martinchuk, A N; E En Gyn; Safronova, A M; Peskova, E V

1991-01-01

Intake of wheat upholstery meal by growing rats was attended by a sharp decrease in the content and activity of xenobiotic metabolism enzymes in the hepatic microsomes, that was caused by the low biological value of the meal proteins. Hepatic microsomes of the rats that were fed with wheat germ flakes showed increased specific content of cytochromes P-450 and b5, but the total blood protein content per 100 g of body mass was lower than during casein consumption. No significant changes were detected in hydroxylation rate of benz(a)pyrene, aniline and ethylmorphine. During consumption of wheat germ flakes induction of UDP-glucuronide-transferase was detected in hepatic microsomes. Wheat germ flakes induced a 5-fold increase of Se-dependent glutathione peroxidase activity. Wheat germ flakes produced no significant effect on glutathione-S-aryltransferase and glutathione reductase activity.

Phase transition of charged-AdS black holes and quasinormal modes: A time domain analysis

NASA Astrophysics Data System (ADS)

Chabab, M.; El Moumni, H.; Iraoui, S.; Masmar, K.

2017-10-01

In this work, we investigate the time evolution of a massless scalar perturbation around small and large RN-AdS4 black holes for the purpose of probing the thermodynamic phase transition. We show that below the critical point the scalar perturbation decays faster with increasing of the black hole size, both for small and large black hole phases. Our analysis of the time profile of quasinormal mode reveals a sharp distinction between the behaviors of both phases, providing a reliable tool to probe the black hole phase transition. However at the critical point P=Pc, as the black hole size extends, we note that the damping time increases and the perturbation decays faster, the oscillation frequencies raise either in small and large black hole phase. In this case the time evolution approach fails to track the AdS4 black hole phase.

Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism

PubMed Central

Lundgaard, Iben; Li, Baoman; Xie, Lulu; Kang, Hongyi; Sanggaard, Simon; Haswell, John Douglas R; Sun, Wei; Goldman, Siri; Blekot, Solomiya; Nielsen, Michael; Takano, Takahiro; Deane, Rashid; Nedergaard, Maiken

2015-01-01

Metabolically, the brain is a highly active organ that relies almost exclusively on glucose as its energy source. According to the astrocyte-to-neuron lactate shuttle hypothesis, glucose is taken up by astrocytes and converted to lactate, which is then oxidized by neurons. Here we show, using 2-photon imaging of a near-infrared 2-deoxyglucose analogue (2DG-IR), that glucose is taken up preferentially by neurons in awake behaving mice. Anesthesia suppressed neuronal 2DG-IR uptake and sensory stimulation was associated with a sharp increase in neuronal, but not astrocytic, 2DG-IR uptake. Moreover, hexokinase, which catalyze the first enzymatic steps in glycolysis, was highly enriched in neurons compared with astrocytes, in mouse as well as in human cortex. These observations suggest that brain activity and neuronal glucose metabolism are directly linked, and identifies the neuron as the principal locus of glucose uptake as visualized by functional brain imaging. PMID:25904018

Orientation-dependent energy level alignment and film growth of 2,7-diocty[1]benzothieno[3,2-b]benzothiophene (C8-BTBT) on HOPG

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyu, Lu; Niu, Dongmei, E-mail: mayee@csu.edu.cnmailto; Xie, Haipeng

Combining ultraviolet photoemission spectroscopy, X-ray photoemission spectroscopy, atomic force microscopy, and X-ray diffraction measurements, we performed a systematic investigation on the correlation of energy level alignment, film growth, and molecular orientation of 2,7-diocty[1]benzothieno[3,2-b]benzothiophene (C8-BTBT) on highly oriented pyrolytic graphite. The molecules lie down in the first layer and then stand up from the second layer. The ionization potential shows a sharp decrease from the lying down region to the standing up region. When C8-BTBT molecules start standing up, unconventional energy level band-bending-like shifts are observed as the film thickness increases. These shifts are ascribed to gradual decreasing of the molecularmore » tilt angle about the substrate normal with the increasing film thickness.« less

Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism.

PubMed

Lundgaard, Iben; Li, Baoman; Xie, Lulu; Kang, Hongyi; Sanggaard, Simon; Haswell, John D R; Sun, Wei; Goldman, Siri; Blekot, Solomiya; Nielsen, Michael; Takano, Takahiro; Deane, Rashid; Nedergaard, Maiken

2015-04-23

Metabolically, the brain is a highly active organ that relies almost exclusively on glucose as its energy source. According to the astrocyte-to-neuron lactate shuttle hypothesis, glucose is taken up by astrocytes and converted to lactate, which is then oxidized by neurons. Here we show, using two-photon imaging of a near-infrared 2-deoxyglucose analogue (2DG-IR), that glucose is taken up preferentially by neurons in awake behaving mice. Anaesthesia suppressed neuronal 2DG-IR uptake and sensory stimulation was associated with a sharp increase in neuronal, but not astrocytic, 2DG-IR uptake. Moreover, hexokinase, which catalyses the first enzymatic steps in glycolysis, was highly enriched in neurons compared with astrocytes, in mouse as well as in human cortex. These observations suggest that brain activity and neuronal glucose metabolism are directly linked, and identify the neuron as the principal locus of glucose uptake as visualized by functional brain imaging.

The misunderstood consequences of Shelley v. Kraemer.

PubMed

Kucheva, Yana; Sander, Richard

2014-11-01

Shelley v. Kraemer (1948) was a landmark civil rights ruling, in which the Supreme Court held that private racial covenants could not be enforced by the state to evict black buyers of "restricted" homes. Fair housing scholars have generally dismissed or downplayed the practical effects of Shelley, since other forms of housing discrimination remained very powerful. Using spatial lag models and detailed geographic data on the location of covenants and patterns of intra-urban black migration, we compare the role of Shelley with other forces shaping mid-century neighborhood change. We find that Shelley precipitated white-to-black neighborhood transitions after 1948 and changed the nature of the dual housing market in important ways. We also show that increased black mobility produced a sharp increase in intra-black economic segregation during the 1950s and 1960s. Copyright © 2014 Elsevier Inc. All rights reserved.

Numerical Modeling of Three-Dimensional Fluid Flow with Phase Change

NASA Technical Reports Server (NTRS)

Esmaeeli, Asghar; Arpaci, Vedat

1999-01-01

We present a numerical method to compute phase change dynamics of three-dimensional deformable bubbles. The full Navier-Stokes and energy equations are solved for both phases by a front tracking/finite difference technique. The fluid boundary is explicitly tracked by discrete points that are connected by triangular elements to form a front that is used to keep the stratification of material properties sharp and to calculate the interfacial source terms. Two simulations are presented to show robustness of the method in handling complex phase boundaries. In the first case, growth of a vapor bubble in zero gravity is studied where large volume increase of the bubble is managed by adaptively increasing the front resolution. In the second case, growth of a bubble under high gravity is studied where indentation at the rear of the bubble results in a region of large curvature which challenges the front tracking in three dimensions.

Evidence That Nitric Acid Increases Relative Humidity in Low-Temperature Cirrus Clouds

NASA Technical Reports Server (NTRS)

Gao, R. S.; Popp, P. J.; Fahey, D. W.; Marcy, T. P.; Herman, R. L.; Weinstock, E. M.; Baumgardner, D. G.; Garrett, T. J.; Rosenlof, K. H.; Thompson, T. L.

2004-01-01

In situ measurements of the relative humidity with respect to ice (RH(sub(i)) and of nitric acid (HNO3) were made in both natural and contrail cirrus clouds in the upper troposphere. At temperatures lower than 202 kelvin, RH(sub i) values show a sharp increase to average values of over 130% in both cloud types. These enhanced RH(sub i) values are attributed to the presence of a new class of NHO3- containing ice particles (Delta-ice). We propose that surface HNO3 molecules prevent the ice/vapor system from reaching equilibrium by a mechanism similar to that of freezing point depression by antifreeze proteins. Delta-ice represents a new link between global climate and natural and anthropogenic nitrogen oxide emissions. Including Delta-ice in climate models will alter simulated cirrus properties and the distribution of upper tropospheric water vapor.

Small nanoparticles, surface geometry and contact forces.

PubMed

Takato, Yoichi; Benson, Michael E; Sen, Surajit

2018-03-01

In this molecular dynamics study, we examine the local surface geometric effects of the normal impact force between two approximately spherical nanoparticles that collide in a vacuum. Three types of surface geometries-(i) crystal facets, (ii) sharp edges, and (iii) amorphous surfaces of small nanoparticles with radii R <10 nm-are considered. The impact forces are compared with their macroscopic counterparts described by nonlinear contact forces based on Hertz contact mechanics. In our simulations, edge and amorphous surface contacts with weak surface energy reveal that the average impact forces are in excellent agreement with the Hertz contact force. On the other hand, facet collisions show a linearly increasing force with increasing compression. Our results suggest that the nearly spherical nanoparticles are likely to enable some nonlinear dynamic phenomena, such as breathers and solitary waves observed in granular materials, both originating from the nonlinear contact force.

PRRT2 Is a Key Component of the Ca2+-Dependent Neurotransmitter Release Machinery

PubMed Central

Valente, Pierluigi; Castroflorio, Enrico; Rossi, Pia; Fadda, Manuela; Sterlini, Bruno; Cervigni, Romina Ines; Prestigio, Cosimo; Giovedì, Silvia; Onofri, Franco; Mura, Elisa; Guarnieri, Fabrizia C.; Marte, Antonella; Orlando, Marta; Zara, Federico; Fassio, Anna; Valtorta, Flavia; Baldelli, Pietro; Corradi, Anna; Benfenati, Fabio

2016-01-01

Summary Heterozygous mutations in proline-rich transmembrane protein 2 (PRRT2) underlie a group of paroxysmal disorders, including epilepsy, kinesigenic dyskinesia, and migraine. Most of the mutations lead to impaired PRRT2 expression, suggesting that loss of PRRT2 function may contribute to pathogenesis. We show that PRRT2 is enriched in presynaptic terminals and that its silencing decreases the number of synapses and increases the number of docked synaptic vesicles at rest. PRRT2-silenced neurons exhibit a severe impairment of synchronous release, attributable to a sharp decrease in release probability and Ca2+ sensitivity and associated with a marked increase of the asynchronous/synchronous release ratio. PRRT2 interacts with the synaptic proteins SNAP-25 and synaptotagmin 1/2. The results indicate that PRRT2 is intimately connected with the Ca2+-sensing machinery and that it plays an important role in the final steps of neurotransmitter release. PMID:27052163

Polarization Sensitive Coherent Anti-Stokes Raman Spectroscopy of DCVJ in Doped Polymer

NASA Astrophysics Data System (ADS)

Ujj, Laszlo

2014-05-01

Coherent Raman Microscopy is an emerging technic and method to image biological samples such as living cells by recording vibrational fingerprints of molecules with high spatial resolution. The race is on to record the entire image during the shortest time possible in order to increase the time resolution of the recorded cellular events. The electronically enhanced polarization sensitive version of Coherent anti-Stokes Raman scattering is one of the method which can shorten the recording time and increase the sharpness of an image by enhancing the signal level of special molecular vibrational modes. In order to show the effectiveness of the method a model system, a highly fluorescence sample, DCVJ in a polymer matrix is investigated. Polarization sensitive resonance CARS spectra are recorded and analyzed. Vibrational signatures are extracted with model independent methods. Details of the measurements and data analysis will be presented. The author gratefully acknowledge the UWF for financial support.

Effect of sputtering power on the growth of Ru films deposited by magnetron sputtering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jhanwar, Prachi, E-mail: prachijhanwar87@gmail.com; Department of Electronics, Banasthali University-304022, Rajasthan; Kumar, Arvind

2016-04-13

Ruthenium is deposited by DC magnetron sputtering at different powers and is characterized. The effect of sputtering power on the electrical and structural properties of the film is investigated experimentally. High resolution X-ray diffraction is used to characterize the microstructure of Ru films deposited on SiO{sub 2} surface. The peak (002) is more sharp and intense with full width at half maximum (FWHM) of 0.37° at 250W. The grain size increases with increase in sputtering power improving the crystallinity of the film. The film deposited at high sputtering power also showed lower resistivity (12.40 µΩ-cm) and higher mobility (4.82 cm{sup 2}/V.s) asmore » compared to the film deposited at low power. The surface morphology of the film is studied by atomic force microscopy (AFM).« less

Segregation of Sb in Ge epitaxial layers and its usage for the selective doping of Ge-based structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Antonov, A. V.; Drozdov, M. N.; Novikov, A. V., E-mail: anov@ipmras.ru

2015-11-15

The segregation of Sb in Ge epitaxial layers grown by the method of molecular beam epitaxy on Ge (001) substrates is investigated. For a growth temperature range of 180–325°C, the temperature dependence is determined for the segregation ratio of Sb in Ge, which shows a sharp increase (by more than three orders of magnitude) with increasing temperature. The strong dependence of the segregation properties of Sb on the growth temperature makes it possible to adapt a method based on the controlled use of segregation developed previously for the doping of Si structures for the selective doping of Ge structures withmore » a donor impurity. Using this method selectively doped Ge:Sb structures, in which the bulk impurity concentration varies by an order of magnitude at distances of 3–5 nm, are obtained.« less

Single-valley quantum Hall ferromagnet in a dilute Mg xZn 1-xO/ZnO strongly correlated two-dimensional electron system

DOE PAGES

Kozuka, Y.; Tsukazaki, A.; Maryenko, D.; ...

2012-02-03

We investigate the spin susceptibility (g*m*) of dilute two-dimensional (2D) electrons confined at the Mg xZn 1-xO/ZnO heterointerface. Magnetotransport measurements show a four-fold enhancement of g*m*, dominated by the increase in the Landé g-factor. The g-factor enhancement leads to a ferromagnetic instability of the electron gas as evidenced by sharp resistance spikes. At high magnetic field, the large g*m* leads to full spin polarization, where we found sudden increase in resistance around the filling factors of half-integer, accompanied by complete disappearance of fractional quantum Hall (QH) states. Along with its large effective mass and the high electron mobility, our resultmore » indicates that the ZnO 2D system is ideal for investigating the effect of electron correlations in the QH regime.« less

Questa Baseline and Pre-Mining Ground-Water Quality Investigation. 1. Depth to Bedrock Determinations Using Shallow Seismic Data Acquired in the Straight Creek Drainage Near Red River, New Mexico

USGS Publications Warehouse

Powers, Michael H.; Burton, Bethany L.

2004-01-01

In late May and early June of 2002, the U.S. Geological Survey (USGS) acquired four P-wave seismic profiles across the Straight Creek drainage near Red River, New Mexico. The data were acquired to support a larger effort to investigate baseline and pre-mining ground-water quality in the Red River basin (Nordstrom and others, 2002). For ground-water flow modeling, knowledge of the thickness of the valley fill material above the bedrock is required. When curved-ray refraction tomography was used with the seismic first arrival times, the resulting images of interval velocity versus depth clearly show a sharp velocity contrast where the bedrock interface is expected. The images show that the interpreted buried bedrock surface is neither smooth nor sharp, but it is clearly defined across the valley along the seismic line profiles. The bedrock models defined by the seismic refraction images are consistent with the well data.

Phase transition of traveling waves in bacterial colony pattern

NASA Astrophysics Data System (ADS)

Wakano, Joe Yuichiro; Komoto, Atsushi; Yamaguchi, Yukio

2004-05-01

Depending on the growth condition, bacterial colonies can exhibit different morphologies. Many previous studies have used reaction diffusion equations to reproduce spatial patterns. They have revealed that nonlinear reaction term can produce diverse patterns as well as nonlinear diffusion coefficient. Typical reaction term consists of nutrient consumption, bacterial reproduction, and sporulation. Among them, the functional form of sporulation rate has not been biologically investigated. Here we report experimentally measured sporulation rate. Then, based on the result, a reaction diffusion model is proposed. One-dimensional simulation showed the existence of traveling wave solution. We study the wave form as a function of the initial nutrient concentration and find two distinct types of solution. Moreover, transition between them is very sharp, which is analogous to phase transition. The velocity of traveling wave also shows sharp transition in nonlinear diffusion model, which is consistent with the previous experimental result. The phenomenon can be explained by separatrix in reaction term dynamics. Results of two-dimensional simulation are also shown and discussed.

Magnetic Turbulence, Fast Magnetic Field line Diffusion and Small Magnetic Structures in the Solar Wind

NASA Astrophysics Data System (ADS)

Zimbardo, G.; Pommois, P.; Veltri, P.

2003-09-01

The influence of magnetic turbulence on magnetic field line diffusion has been known since the early days of space and plasma physics. However, the importance of ``stochastic diffusion'' for energetic particles has been challenged on the basis of the fact that sharp gradients of either energetic particles or ion composition are often observed in the solar wind. Here we show that fast transverse field line and particle diffusion can coexist with small magnetic structures, sharp gradients, and with long lived magnetic flux tubes. We show, by means of a numerical realization of three dimensional magnetic turbulence and by use of the concepts of deterministic chaos and turbulent transport, that turbulent diffusion is different from Gaussian diffusion, and that transport can be inhomogeneous even if turbulence homogeneously fills the heliosphere. Several diagnostics of field line transport and flux tube evolution are shown, and the size of small magnetic structures in the solar wind, like gradient scales and flux tube thickness, are estimated and compared to the observations.

Decoding synchronized oscillations within the brain: phase-delayed inhibition provides a robust mechanism for creating a sharp synchrony filter.

PubMed

Patel, Mainak; Joshi, Badal

2013-10-07

The widespread presence of synchronized neuronal oscillations within the brain suggests that a mechanism must exist that is capable of decoding such activity. Two realistic designs for such a decoder include: (1) a read-out neuron with a high spike threshold, or (2) a phase-delayed inhibition network motif. Despite requiring a more elaborate network architecture, phase-delayed inhibition has been observed in multiple systems, suggesting that it may provide inherent advantages over simply imposing a high spike threshold. In this work, we use a computational and mathematical approach to investigate the efficacy of the phase-delayed inhibition motif in detecting synchronized oscillations. We show that phase-delayed inhibition is capable of creating a synchrony detector with sharp synchrony filtering properties that depend critically on the time course of inputs. Additionally, we show that phase-delayed inhibition creates a synchrony filter that is far more robust than that created by a high spike threshold. Copyright © 2013 Elsevier Ltd. All rights reserved.

Fabrication of a high sensitivity and fast response self-powered photosensor based on a core-shell silicon nanowire homojunction

NASA Astrophysics Data System (ADS)

Abdul-Hameed, Assel A.; Mahdi, M. A.; Ali, Basil; Selman, Abbas M.; Al-Taay, H. F.; Jennings, P.; Lee, Wen-Jen

2018-04-01

Core-shell self-powered SiNWs homojunction photosensors have been fabricated. SiNWs are prepared by a metal assisted chemical etching method using different HF/H2O2 ratios and etching times. The length of the p-SiNWs increased as the H2O2 concentration and etching time increased. All the grown SiNWs show very low (∼0.7%) optical reflectance for the wavelength range of 200-1100 nm. Photoluminescence spectra of all prepared SiNWs show sharp and broad emission bands located in the red region of the light spectrum. Core-shell homojunction photosensors were fabricated by spin coating P2O2 onto the surface of the prepared p-SiNWs and annealed at 900 °C for 1 h. The fabricated devices exhibited photovoltaic behavior and high photosensitivity with fast response speed to the visible light. However, the sample that was fabricated using HF/H2O2 ratio of 1:1 showed the highest photosensitivity value of 3578% while the photosensor prepared using 2:1 ratio of HF/H2O2 gave the faster rise and decay time.

The effect of image sharpness on quantitative eye movement data and on image quality evaluation while viewing natural images

NASA Astrophysics Data System (ADS)

Vuori, Tero; Olkkonen, Maria

2006-01-01

The aim of the study is to test both customer image quality rating (subjective image quality) and physical measurement of user behavior (eye movements tracking) to find customer satisfaction differences in imaging technologies. Methodological aim is to find out whether eye movements could be quantitatively used in image quality preference studies. In general, we want to map objective or physically measurable image quality to subjective evaluations and eye movement data. We conducted a series of image quality tests, in which the test subjects evaluated image quality while we recorded their eye movements. Results show that eye movement parameters consistently change according to the instructions given to the user, and according to physical image quality, e.g. saccade duration increased with increasing blur. Results indicate that eye movement tracking could be used to differentiate image quality evaluation strategies that the users have. Results also show that eye movements would help mapping between technological and subjective image quality. Furthermore, these results give some empirical emphasis to top-down perception processes in image quality perception and evaluation by showing differences between perceptual processes in situations when cognitive task varies.

Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye.

PubMed

Rodrigues, Paulo M G; Grigaravicius, Paulius; Remus, Martina; Cavalheiro, Gabriel R; Gomes, Anielle L; Rocha-Martins, Maurício; Martins, Mauricio R; Frappart, Lucien; Reuss, David; McKinnon, Peter J; von Deimling, Andreas; Martins, Rodrigo A P; Frappart, Pierre-Olivier

2013-01-01

Nibrin (NBN or NBS1) and ATM are key factors for DNA Double Strand Break (DSB) signaling and repair. Mutations in NBN or ATM result in Nijmegen Breakage Syndrome and Ataxia telangiectasia. These syndromes share common features such as radiosensitivity, neurological developmental defects and cancer predisposition. However, the functional synergy of Nbn and Atm in different tissues and developmental stages is not yet understood. Here, we show in vivo consequences of conditional inactivation of both genes in neural stem/progenitor cells using Nestin-Cre mice. Genetic inactivation of Atm in the central nervous system of Nbn-deficient mice led to reduced life span and increased DSBs, resulting in increased apoptosis during neural development. Surprisingly, the increase of DSBs and apoptosis was found only in few tissues including cerebellum, ganglionic eminences and lens. In sharp contrast, we showed that apoptosis associated with Nbn deletion was prevented by simultaneous inactivation of Atm in developing retina. Therefore, we propose that Nbn and Atm collaborate to prevent DSB accumulation and apoptosis during development in a tissue- and developmental stage-specific manner.

[Question marks concerning serological tests in congenital toxoplasmosis - a case report].

PubMed

Prášil, Petr; Cermáková, Zuzana; Boštík, Pavel; Smahel, Petr; Plíšek, Stanislav

2012-12-01

Two weeks after delivery of a healthy term neonate, the mother developed lymph node syndrome, which corresponded serologically to acute toxoplasmosis. The blood of the newborn showed positive IgM, IgG and IgA antibody titers against Toxoplasma gondii with a low avidity of IgG. The newborn did not show any clinical signs or organ damage connected to toxoplasmosis either at the beginning or during the follow-up. The IgA and IgM titers exhibited a decrease over time, while the KFR, IgG antibody titers and avidity had an increasing trend. A sharp increase of KFR, IgE and IgA antibody titers was detected during the sixth month of life, probably due to maturation of the immune system in the setting of an asymptomatic infection with T. gondii. This short increase was followed by a subsequent decrease in titers of these antibodies until they reached negative levels during the 21st month of life. The evaluation of serological results in newborns infected with T. gondii is always difficult and should be performed by an expert physician. Children at risk should be placed under a long-term follow-up to avoid potential development of toxoplasma chorioretinitis.

Nanoclustering phase competition induces the resistivity hump in colossal magnetoresistive manganites

NASA Astrophysics Data System (ADS)

Pradhan, Kalpataru; Yunoki, Seiji

2017-12-01

Using a two-band double-exchange model with Jahn-Teller lattice distortions and superexchange interactions, supplemented by quenched disorder, at an electron density n =0.65 , we explicitly demonstrate the coexistence of the n =1 /2 -type (π ,π ) charge-ordered and the ferromagnetic nanoclusters above the ferromagnetic transition temperature Tc in colossal magnetoresistive (CMR) manganites. The resistivity increases due to the enhancement of the volume fraction of the charge-ordered and the ferromagnetic nanoclusters upon decreasing the temperature down to Tc. The ferromagnetic nanoclusters start to grow and merge, and the volume fraction of the charge-ordered nanoclusters decreases below Tc, leading to the sharp drop in the resistivity. By applying a small external magnetic field h , we show that the resistivity above Tc increases, as compared with the case when h =0 , a fact that further confirms the coexistence of the charge-ordered and the ferromagnetic nanoclusters. In addition, we show that the volume fraction of the charge-ordered nanoclusters decreases upon increasing the bandwidth, and consequently the resistivity hump diminishes for large bandwidth manganites, in good qualitative agreement with experiments. The obtained insights from our calculations provide a complete pathway to understand the phase competition in CMR manganites.

Magnetism of Ho 1-xTb xAl₂ alloys: Critical dependence of a first-order transition on Tb concentration

DOE PAGES

Khan, Mahmud; Mudryk, Ya.; Gschneidner, K. A.; ...

2011-12-27

HoAl₂ exhibits a first-order spin reorientation transition at 20 K, which is manifested as a sharp peak in the heat capacity. When Ho is partially replaced by only 5% of Tb, the sharp heat-capacity peak in Ho 1-xTb xAl₂ (x = 0.05) disappears, and then reappears again for x ≥ 0.07. For x = 0.05, the anomaly corresponding to the spin reorientation transition is barely seen in the heat capacity, but as x exceeds 0.07 the weak anomaly transforms to a sharp peak. The spin reorientation transition temperature increases to 29 K for x = 0.05, and as x increasesmore » further the transition shifts to lower temperature and returns to ~20 K for x = 0.25. The transition is no longer observed when x exceeds 0.60. Temperature-dependent x-ray powder-diffraction data confirm the first-order nature of the spin reorientation transition for the alloy with x = 0.40, and indicate that the compound retains the room-temperature cubic structure within the sensitivity of the technique. Experimental observations are discussed considering the easy magnetization directions of HoAl₂ and TbAl₂.« less

On the incidence of meteorological and hydrological processors: Effect of resolution, sharpness and reliability of hydrological ensemble forecasts

NASA Astrophysics Data System (ADS)

Abaza, Mabrouk; Anctil, François; Fortin, Vincent; Perreault, Luc

2017-12-01

Meteorological and hydrological ensemble prediction systems are imperfect. Their outputs could often be improved through the use of a statistical processor, opening up the question of the necessity of using both processors (meteorological and hydrological), only one of them, or none. This experiment compares the predictive distributions from four hydrological ensemble prediction systems (H-EPS) utilising the Ensemble Kalman filter (EnKF) probabilistic sequential data assimilation scheme. They differ in the inclusion or not of the Distribution Based Scaling (DBS) method for post-processing meteorological forecasts and the ensemble Bayesian Model Averaging (ensemble BMA) method for hydrological forecast post-processing. The experiment is implemented on three large watersheds and relies on the combination of two meteorological reforecast products: the 4-member Canadian reforecasts from the Canadian Centre for Meteorological and Environmental Prediction (CCMEP) and the 10-member American reforecasts from the National Oceanic and Atmospheric Administration (NOAA), leading to 14 members at each time step. Results show that all four tested H-EPS lead to resolution and sharpness values that are quite similar, with an advantage to DBS + EnKF. The ensemble BMA is unable to compensate for any bias left in the precipitation ensemble forecasts. On the other hand, it succeeds in calibrating ensemble members that are otherwise under-dispersed. If reliability is preferred over resolution and sharpness, DBS + EnKF + ensemble BMA performs best, making use of both processors in the H-EPS system. Conversely, for enhanced resolution and sharpness, DBS is the preferred method.

Lamina-specific contribution of glutamatergic and GABAergic potentials to hippocampal sharp wave-ripple complexes.

PubMed

Schönberger, Jan; Draguhn, Andreas; Both, Martin

2014-01-01

The mammalian hippocampus expresses highly organized patterns of neuronal activity which form a neuronal correlate of spatial memories. These memory-encoding neuronal ensembles form on top of different network oscillations which entrain neurons in a state- and experience-dependent manner. The mechanisms underlying activation, timing and selection of participating neurons are incompletely understood. Here we studied the synaptic mechanisms underlying one prominent network pattern called sharp wave-ripple complexes (SPW-R) which are involved in memory consolidation during sleep. We recorded SPW-R with extracellular electrodes along the different layers of area CA1 in mouse hippocampal slices. Contribution of glutamatergic excitation and GABAergic inhibition, respectively, was probed by local application of receptor antagonists into s. radiatum, pyramidale and oriens. Laminar profiles of field potentials show that GABAergic potentials contribute substantially to sharp waves and superimposed ripple oscillations in s. pyramidale. Inhibitory inputs to s. pyramidale and s. oriens are crucial for action potential timing by ripple oscillations, as revealed by multiunit-recordings in the pyramidal cell layer. Glutamatergic afferents, on the other hand, contribute to sharp waves in s. radiatum where they also evoke a fast oscillation at ~200 Hz. Surprisingly, field ripples in s. radiatum are slightly slower than ripples in s. pyramidale, resulting in a systematic shift between dendritic and somatic oscillations. This complex interplay between dendritic excitation and perisomatic inhibition may be responsible for the precise timing of discharge probability during the time course of SPW-R. Together, our data illustrate a complementary role of spatially confined excitatory and inhibitory transmission during highly ordered network patterns in the hippocampus.

Impact of recycling on the mechanical and thermo-mechanical properties of wood flour/high density polyethylene and wood flour/poly lactic acid composites

NASA Astrophysics Data System (ADS)

Bhattacharjee, Sujal

This research concentrates on the recyclability of two wood plastic composites (WPCs)--wood flour/HDPE and wood flour/PLA composites. Two different filler loadings (30 and 50 wt%) were considered for each polymer composite. Each composite formulation contained 3 wt% of a coupling agent, and was individually recycled up to six times by extrusion process. Samples for mechanical and thermo-mechanical tests were prepared by injection molding. All test results were statistically analyzed with a confidence level of 95%. Additional tests such as fiber length measurement, GPC, DSC, TGA, FTIR, and SEM were also performed at specific reprocessing cycles. After reprocessing six times, all formulations showed lower relative decrease in most stiffness properties but higher relative increase in most strain properties. In strength properties, both HDPE composites showed lower relative decrease after reprocessed six times; however, higher and lower filler PLA composites showed sharp decrease reprocessed at second and six times respectively.

Endangered Language Families

ERIC Educational Resources Information Center

Whalen, D. H.; Simons, Gary F.

2012-01-01

Linguists have increased their documentation efforts in response to the sharp decline in the number of languages. Greater awareness and new sources of funding have led to an upsurge in language documentation. While individual languages make unique contributions to the world's linguistic heritage, language families, by virtue of their shared…

CHARACTERIZATION AND REDUCTION OF FORMALDEHYDE EMISSIONS FROM A LOW-VOC LATEX PAINT

EPA Science Inventory

The paper discusses the measurment and analysis of the patterns of formaldehyde emission from a low volatile organic compound (VOC) latex paint applied to gypsum board, using small environmental chamber tests. The formaldehyde emissions resulted in sharp increase of chamber air...

Indian pharmaceutical patent prosecution: The changing role of Section 3(d).

PubMed

Sampat, Bhaven N; Shadlen, Kenneth C

2018-01-01

India, like many developing countries, only recently began to grant pharmaceutical product patents. Indian patent law includes a provision, Section 3(d), which tries to limit grant of "secondary" pharmaceutical patents, i.e. patents on new forms of existing molecules and drugs. Previous research suggests the provision was rarely used against secondary applications in the years immediately following its enactment, and where it was, was redundant to other aspects of the patent law, raising concerns that 3(d) was being under-utilized by the Indian Patent Office. This paper uses a novel data source, the patent office's first examination reports, to examine changes in the use of the provision. We find a sharp increase over time in the use of Section 3(d), including on the main claims of patent applications, though it continues to be used in conjunction with other types of objections to patentability. More surprisingly, see a sharp increase in the use of the provision against primary patent applications, contrary to its intent, raising concerns about potential over-utilization.

Interplay between Hippocampal Sharp-Wave-Ripple Events and Vicarious Trial and Error Behaviors in Decision Making.

PubMed

Papale, Andrew E; Zielinski, Mark C; Frank, Loren M; Jadhav, Shantanu P; Redish, A David

2016-12-07

Current theories posit that memories encoded during experiences are subsequently consolidated into longer-term storage. Hippocampal sharp-wave-ripple (SWR) events have been linked to this consolidation process during sleep, but SWRs also occur during awake immobility, where their role remains unclear. We report that awake SWR rates at the reward site are inversely related to the prevalence of vicarious trial and error (VTE) behaviors, thought to be involved in deliberation processes. SWR rates were diminished immediately after VTE behaviors and an increase in the rate of SWR events at the reward site predicted a decrease in subsequent VTE behaviors at the choice point. Furthermore, SWR disruptions increased VTE behaviors. These results suggest an inverse relationship between SWRs and VTE behaviors and suggest that awake SWRs and associated planning and memory consolidation mechanisms are engaged specifically in the context of higher levels of behavioral certainty. Copyright © 2016 Elsevier Inc. All rights reserved.

Geology of the Early Arikareean sharps formation on the Pine Ridge Indian Reservation and surrounding areas of South Dakota and Nebraska.

PubMed

McConnell, Thomas H; Dibenedetto, Joseph N

2012-01-01

Based on geologic mapping, measured sections, and lithologic correlations, the local features of the upper and lower type areas of the Early Arikareean (30.8-20.6 million years ago) Sharps Formation are revised and correlated. The Sharps Formation above the basal Rockyford Member is divided into two members of distinct lithotypes. The upper 233 feet of massive siltstones and sandy siltstones is named the Gooseneck Road Member. The middle member, 161 feet of eolian volcaniclastic siltstones with fluvially reworked volcaniclastic lenses and sandy siltstone sheets, is named the Wolff Camp Member. An ashey zone at the base of the Sharps Formation is described and defined as the Rockyford Ash Zone (RAZ) in the same stratigraphic position as the Nonpareil Ash Zone (NPAZ) in Nebraska. Widespread marker beds of fresh water limestones at 130 feet above the base of the Sharps Formation and a widespread reddish-brown clayey siltstone at 165 feet above the base of the Sharps Formation are described. The Brown Siltstone Beds of Nebraska are shown to be a southern correlative of the Wolff Camp Member and the Rockyford Member of the Sharps Formation. Early attempts to correlate strata in the Great Plains were slow in developing. Recognition of the implications of the paleomagnetic and lithologic correlations of this paper will provide an added datum assisting researchers in future biostratigraphic studies. Based on similar lithologies, the Sharps Formation, currently assigned to the Arikaree Group, should be reassigned to the White River Group.

Surface-Pressure and Flow-Visualization Data at Mach Number of 1.60 for Three 65 deg Delta Wings Varying in Leading-Edge Radius and Camber

NASA Technical Reports Server (NTRS)

McMillin, S. Naomi; Bryd, James E.; Parmar, Devendra S.; Bezos-OConnor, Gaudy M.; Forrest, Dana K.; Bowen, Susan

1996-01-01

An experimental investigation of the effect of leading-edge radius, camber, Reynolds number, and boundary-layer state on the incipient separation of a delta wing at supersonic speeds was conducted at the Langley Unitary Plan Wind Tunnel at Mach number of 1.60 over a free-stream Reynolds number range of 1 x 106 to 5 x 106 ft-1. The three delta wing models examined had a 65 deg swept leading edge and varied in cross-sectional shape: a sharp wedge, a 20:1 ellipse, and a 20:1 ellipse with a -9.750 circular camber imposed across the span. The wings were tested with and without transition grit applied. Surface-pressure coefficient data and flow-visualization data indicated that by rounding the wing leading edge or cambering the wing in the spanwise direction, the onset of leading-edge separation on a delta wing can be raised to a higher angle of attack than that observed on a sharp-edged delta wing. The data also showed that the onset of leading-edge separation can be raised to a higher angle of attack by forcing boundary-layer transition to occur closer to the wing leading edge by the application of grit or the increase in free-stream Reynolds number.

Source localization of small sharp spikes: low resolution electromagnetic tomography (LORETA) reveals two distinct cortical sources.

PubMed

Zumsteg, Dominik; Andrade, Danielle M; Wennberg, Richard A

2006-06-01

We have investigated the cortical sources and electroencephalographic (EEG) characteristics of small sharp spikes (SSS) by using statistical non-parametric mapping (SNPM) of low resolution electromagnetic tomography (LORETA). We analyzed 7 SSS patterns (501 individual SSS) in 6 patients who underwent sleep EEG studies with 29 or 23 scalp electrodes. The scalp signals were averaged time-locked to the SSS peak activity and subjected to SNPM of LORETA values. All 7 SSS patterns (mean 72 individual SSS, range 11-200) revealed a very similar and highly characteristic transhemispheric oblique scalp voltage distribution comprising a first negative field maximum over ipsilateral lateral temporal areas, followed by a second negative field maximum over the contralateral subtemporal region approximately 30 ms later. SNPM-LORETA consistently localized the first component into the ipsilateral posterior insular region, and the second component into ipsilateral posterior mesial temporo-occipital structures. SSS comprise an amalgam of two sequential, distinct cortical components, showing a very uniform and peculiar EEG pattern and cortical source solutions. As such, they must be clearly distinguished from interictal epileptiform discharges in patients with epilepsy. The awareness of these peculiar EEG characteristics may increase our ability to differentiate SSS from interictal epileptiform activity. The finding of a posterior insular source might serve as an inspiration for new physiological considerations regarding these enigmatic waveforms.

Effects of Nose Bluntness on Stability of Hypersonic Boundary Layers over Blunt Cone

NASA Technical Reports Server (NTRS)

Kara, K.; Balakumar, P.; Kandil, O. A.

2007-01-01

Receptivity and stability of hypersonic boundary layers are numerically investigated for boundary layer flows over a 5-degree straight cone at a free-stream Mach number of 6.0. To compute the shock and the interaction of shock with the instability waves, we solve the Navier-Stokes equations in axisymmetric coordinates. The governing equations are solved using the 5th-order accurate weighted essentially non-oscillatory (WENO) scheme for space discretization and using third-order total-variation-diminishing (TVD) Runge-Kutta scheme for time integration. After the mean flow field is computed, disturbances are introduced at the upstream end of the computational domain. Generation of instability waves from leading edge region and receptivity of boundary layer to slow acoustic waves are investigated. Computations are performed for a cone with nose radii of 0.001, 0.05 and 0.10 inches that give Reynolds numbers based on the nose radii ranging from 650 to 130,000. The linear stability results showed that the bluntness has a strong stabilizing effect on the stability of axisymmetric boundary layers. The transition Reynolds number for a cone with the nose Reynolds number of 65,000 is increased by a factor of 1.82 compared to that for a sharp cone. The receptivity coefficient for a sharp cone is about 4.23 and it is very small, approx.10(exp -3), for large bluntness.

A hybrid CFD/characteristics method for fast characterization of hypersonic blunt forebody/inlet flow

NASA Astrophysics Data System (ADS)

Gao, WenZhi; Li, ZhuFei; Yang, JiMing

2015-10-01

A hybrid CFD/characteristic method (CCM) was proposed for fast design and evaluation of hypersonic inlet flow with nose bluntness, which targets the combined advantages of CFD and method of characteristics. Both the accuracy and efficiency of the developed CCM were verified reliably, and it was well demonstrated for the external surfaces design of a hypersonic forebody/inlet with nose bluntness. With the help of CCM method, effects of nose bluntness on forebody shock shapes and the flowfield qualities which dominate inlet performance were examined and analyzed on the two-dimensional and axisymmetric configurations. The results showed that blunt effects of a wedge forebody are more substantial than that of related cone cases. For a conical forebody with a properly blunted nose, a recovery of the shock front back to that of corresponding sharp nose is exhibited, accompanied with a gradually fading out of entropy layer effects. Consequently a simplification is thought to be reasonable for an axisymmetric inlet with a proper compression angle, and a blunt nose of limited radius can be idealized as a sharp nose, as the spillage and flow variations at the entrance are negligible, even though the nose scale increases to 10% cowl lip radius. Whereas for two-dimensional inlets, the blunt effects are substantial since not only the inlet capturing/starting capabilities, but also the flow uniformities are obviously degraded.

Axonal properties determine somatic firing in a model of in vitro CA1 hippocampal sharp wave/ripples and persistent gamma oscillations

PubMed Central

Traub, Roger D.; Schmitz, Dietmar; Maier, Nikolaus; Whittington, Miles A.; Draguhn, Andreas

2012-01-01

Evidence has been presented that CA1 pyramidal cells, during spontaneous in vitro sharp wave/ripple (SPW-R) complexes, generate somatic action potentials that originate in axons. ‘Participating’ (somatically firing) pyramidal cells fire (almost always) at most once during a particular SPW-R whereas non-participating cells virtually never fire during an SPW-R. Somatic spikelets were small or absent, while ripple-frequency EPSCs and IPSCs occurred during the SPW-R in pyramidal neurons. These experimental findings could be replicated with a network model in which electrical coupling was present between small pyramidal cell axonal branches. Here, we explore this model in more depth. Factors that influence somatic participation include: (i) the diameter of axonal branches that contain coupling sites to other axons, because firing in larger branches injects more current into the main axon, increasing antidromic firing probability; (ii) axonal K+ currents; and (iii) somatic hyperpolarization and shunting. We predict that portions of axons fire at high frequency during SPW-R, while somata fire much less. In the model, somatic firing can occur by occasional generation of full action potentials in proximal axonal branches, which are excited by high-frequency spikelets. When the network contains phasic synaptic inhibition, at the axonal gap junction site, gamma oscillations result, again with more frequent axonal firing than somatic firing. Combining the models, so as to generate gamma followed by sharp waves, leads to strong overlap between the population of cells firing during gamma the population of cells firing during a subsequent sharp wave, as observed in vivo. PMID:22697272

Spatio-temporal specialization of GABAergic septo-hippocampal neurons for rhythmic network activity.

PubMed

Unal, Gunes; Crump, Michael G; Viney, Tim J; Éltes, Tímea; Katona, Linda; Klausberger, Thomas; Somogyi, Peter

2018-03-03

Medial septal GABAergic neurons of the basal forebrain innervate the hippocampus and related cortical areas, contributing to the coordination of network activity, such as theta oscillations and sharp wave-ripple events, via a preferential innervation of GABAergic interneurons. Individual medial septal neurons display diverse activity patterns, which may be related to their termination in different cortical areas and/or to the different types of innervated interneurons. To test these hypotheses, we extracellularly recorded and juxtacellularly labeled single medial septal neurons in anesthetized rats in vivo during hippocampal theta and ripple oscillations, traced their axons to distant cortical target areas, and analyzed their postsynaptic interneurons. Medial septal GABAergic neurons exhibiting different hippocampal theta phase preferences and/or sharp wave-ripple related activity terminated in restricted hippocampal regions, and selectively targeted a limited number of interneuron types, as established on the basis of molecular markers. We demonstrate the preferential innervation of bistratified cells in CA1 and of basket cells in CA3 by individual axons. One group of septal neurons was suppressed during sharp wave-ripples, maintained their firing rate across theta and non-theta network states and mainly fired along the descending phase of CA1 theta oscillations. In contrast, neurons that were active during sharp wave-ripples increased their firing significantly during "theta" compared to "non-theta" states, with most firing during the ascending phase of theta oscillations. These results demonstrate that specialized septal GABAergic neurons contribute to the coordination of network activity through parallel, target area- and cell type-selective projections to the hippocampus.

Stochastic Model of Supercoiling-Dependent Transcription

NASA Astrophysics Data System (ADS)

Brackley, C. A.; Johnson, J.; Bentivoglio, A.; Corless, S.; Gilbert, N.; Gonnella, G.; Marenduzzo, D.

2016-07-01

We propose a stochastic model for gene transcription coupled to DNA supercoiling, where we incorporate the experimental observation that polymerases create supercoiling as they unwind the DNA helix and that these enzymes bind more favorably to regions where the genome is unwound. Within this model, we show that when the transcriptionally induced flux of supercoiling increases, there is a sharp crossover from a regime where torsional stresses relax quickly and gene transcription is random, to one where gene expression is highly correlated and tightly regulated by supercoiling. In the latter regime, the model displays transcriptional bursts, waves of supercoiling, and up regulation of divergent or bidirectional genes. It also predicts that topological enzymes which relax twist and writhe should provide a pathway to down regulate transcription.

Financial instability from local market measures

NASA Astrophysics Data System (ADS)

Bardoscia, Marco; Livan, Giacomo; Marsili, Matteo

2012-08-01

We study the emergence of instabilities in a stylized model of a financial market, when different market actors calculate prices according to different (local) market measures. We derive typical properties for ensembles of large random markets using techniques borrowed from statistical mechanics of disordered systems. We show that, depending on the number of financial instruments available and on the heterogeneity of local measures, the market moves from an arbitrage-free phase to an unstable one, where the complexity of the market—as measured by the diversity of financial instruments—increases, and arbitrage opportunities arise. A sharp transition separates the two phases. Focusing on two different classes of local measures inspired by real market strategies, we are able to analytically compute the critical lines, corroborating our findings with numerical simulations.

Laser therapy by noncoherent light field of radiation.

PubMed

Djibladze, M I; Melikishvili, Z G; Uchaneishvili, S D

1997-01-01

Conducted researches on study of interaction of radiation with blood have shown, that the interaction is the most effective for light with wavelengths in the range of 600-1000 nm that corresponds to the minimum absorption factor of the whole blood. Calculations show, that at interaction of radiation with blood considerably grows effective (electronic) temperature of biological environment, that results in sharp increase of speed of biochemical reactions. The absence of necessity of application of laser radiation coherence in lasertherapy permits to create high efficient noncoherent sources of light on the basis of the GaALAs(Zn) crystals, radiating with two maxima of wavelengths 675 and 900 nm. The radiation spectrum of GaALAs(Zn) crystals falls in the most favourable area of a blood absorption spectrum.

Dehydration and crystallization kinetics of zirconia-yttria gels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ramanathan, S.; Muraleedharan, R.V.; Roy, S.K.

1995-02-01

Zirconia and zirconia-yttria gels containing 4 and 8 mol% yttria were obtained by coprecipitation and drying at 373 K. The dehydration and crystallization behavior of the dried gels was studied by DSC, TG, and XRD. The gels undergo elimination of water over a wide temperature range of 373--673 K. The peak temperature of the endotherm corresponding to dehydration and the kinetic constants for the process were not influenced by the yttria content of the gel. The enthalpy of dehydration observed was in good agreement with the heat of vaporization data. The dehydration was followed by a sharp exothermic crystallization process.more » The peak temperature of the exotherm and the activation energy of the process increased with an increase in yttria content, while the enthalpy of crystallization showed a decrease. The ``glow effect`` reduced with increasing yttria content. Pure zirconia crystallizes in the tetragonal form while the zirconia containing 4 and 8 mol% yttria appears to crystallize in the cubic form.« less

First-order transitions and thermodynamic properties in the 2D Blume-Capel model: the transfer-matrix method revisited

NASA Astrophysics Data System (ADS)

Jung, Moonjung; Kim, Dong-Hee

2017-12-01

We investigate the first-order transition in the spin-1 two-dimensional Blume-Capel model in square lattices by revisiting the transfer-matrix method. With large strip widths increased up to the size of 18 sites, we construct the detailed phase coexistence curve which shows excellent quantitative agreement with the recent advanced Monte Carlo results. In the deep first-order area, we observe the exponential system-size scaling of the spectral gap of the transfer matrix from which linearly increasing interfacial tension is deduced with decreasing temperature. We find that the first-order signature at low temperatures is strongly pronounced with much suppressed finite-size influence in the examined thermodynamic properties of entropy, non-zero spin population, and specific heat. It turns out that the jump at the transition becomes increasingly sharp as it goes deep into the first-order area, which is in contrast to the Wang-Landau results where finite-size smoothing gets more severe at lower temperatures.

From Serenity to Langemak - A regional chemical setting for Mare Crisium

NASA Technical Reports Server (NTRS)

Hubbard, N. J.; Keith, J. E.; Vilas, F.

1978-01-01

The chemistry of the region surrounding Mare Crisium is described using improved Al/Si and Mg/Si intensity ratios derived from Apollo 15 X-ray fluorescence measurements. Mg/Si ratios are shown to increase from 0.6 in the region east of Mare Smythii to 1.0 in western Mare Serenitatis, while Al/Si ratios show sharp decreases in all mare areas. It is concluded that the terra (nonmare) material has a uniform Al/Si ratio, hence plagioclase content, and increases in the Mg/Si ratio in terra material imply similar increases of Mg in the pyroxenes and olivines of this material. The observed diversity of terra soils can be explained by an originally chemically diverse region not homogenized by heavy bombardment, or by volcanism subsequent to bombardment. Maria Crisium, Serenitatis and Smythii are found to be filled with low albedo materials which have a wide range of Mg/Si values, with small and apparently consistent differences in Al/Si ratio.

U.S. Energy: Aviation Perspective,

DTIC Science & Technology

1983-11-01

U.S. will continue to meet most of its needs. Taxes and regulations of various kinds are the strongest deterrents to increased U.S. production...34 When these higher prices caused a sharp increase of oil company profits, Congress imposed the "Windfall Profits Tax " on domestic crude oil. "This is...until at least year 2000, can easily increase fuel prices by 100% 17. Key Words 18. Distribution Statement Aviation fuel Fuel conservation This

A comparison of coupled freshwater-saltwater sharp-interface and convective-dispersive models of saltwater intrusion in a layered aquifer system

USGS Publications Warehouse

Hill, Mary C.

1988-01-01

Simulated results of the coupled freshwater-saltwater sharp interface and convective-dispersive numerical models are compared by using steady-state cross-sectional simulations. The results indicate that in some aquifers the calculated sharp interface is located further landward than would be expected.

Notes on distribution and ecology of Philonthus spinipes Sharp (Coleoptera: Staphylinidae) in the Polish Carpathians.

PubMed

Mazur, Andrzej; Guo, Wanyue; Górz, Andrzej

2017-11-30

Philonthus spinipes Sharp for the first time was described from East Asia (Sharp 1874). Presently the species occurs in the whole Palaearctic region. Original distribution of this species is difficult to define because it has obviously extended its distribution range westwards (Schillhammer 1999).

Development of the Adult Scale of Hostility and Aggression: Reactive-Proactive (A-SHARP)

ERIC Educational Resources Information Center

Matlock, Scott Thomas; Aman, Michael G.

2011-01-01

In this study, the authors developed the Adult Scale of Hostility and Aggression Reactive-Proactive (A-SHARP). Sixty-one caregivers rated 512 individuals with intellectual and developmental disabilities on the A-SHARP. Exploratory factor analysis revealed 5 factors on the Problem Scale: (a) Verbal Aggression, (b) Physical Aggression, (c) Hostile…

The Russian Way of War: Post Soviet Adaptations in the Russian Military

DTIC Science & Technology

2013-12-13

226Thomas Goltz , Georgia Diary (London: M. E. Sharpe, 2006), 253. 227Pavel Felgenhauer, “After August 7: The Escalation of the Russian-Georgian War,” in The...Sharpe, 2009. Goltz , Thomas. Georgia Diary. London: M. E. Sharpe, 2006. Goytisolo, Juan. Landscapes of War: From Sarajevo to Chechnya. Translated

Numerical analysis of mixing by sharp-edge-based acoustofluidic micromixer

NASA Astrophysics Data System (ADS)

Nama, Nitesh; Huang, Po-Hsun; Jun Huang, Tony; Costanzo, Francesco

2015-11-01

Recently, acoustically oscillated sharp-edges have been employed to realize rapid and homogeneous mixing at microscales (Huang, Lab on a Chip, 13, 2013). Here, we present a numerical model, qualitatively validated by experimental results, to analyze the acoustic mixing inside a sharp-edge-based micromixer. We extend our previous numerical model (Nama, Lab on a Chip, 14, 2014) to combine the Generalized Lagrangian Mean (GLM) theory with the convection-diffusion equation, while also allowing for the presence of a background flow as observed in a typical sharp-edge-based micromixer. We employ a perturbation approach to divide the flow variables into zeroth-, first- and second-order fields which are successively solved to obtain the Lagrangian mean velocity. The Langrangian mean velocity and the background flow velocity are further employed with the convection-diffusion equation to obtain the concentration profile. We characterize the effects of various operational and geometrical parameters to suggest potential design changes for improving the mixing performance of the sharp-edge-based micromixer. Lastly, we investigate the possibility of generation of a spatio-temporally controllable concentration gradient by placing sharp-edge structures inside the microchannel.

SHARP: A multi-mission artificial intelligence system for spacecraft telemetry monitoring and diagnosis

NASA Technical Reports Server (NTRS)

Lawson, Denise L.; James, Mark L.

1989-01-01

The Spacecraft Health Automated Reasoning Prototype (SHARP) is a system designed to demonstrate automated health and status analysis for multi-mission spacecraft and ground data systems operations. Telecommunications link analysis of the Voyager 2 spacecraft is the initial focus for the SHARP system demonstration which will occur during Voyager's encounter with the planet Neptune in August, 1989, in parallel with real time Voyager operations. The SHARP system combines conventional computer science methodologies with artificial intelligence techniques to produce an effective method for detecting and analyzing potential spacecraft and ground systems problems. The system performs real time analysis of spacecraft and other related telemetry, and is also capable of examining data in historical context. A brief introduction is given to the spacecraft and ground systems monitoring process at the Jet Propulsion Laboratory. The current method of operation for monitoring the Voyager Telecommunications subsystem is described, and the difficulties associated with the existing technology are highlighted. The approach taken in the SHARP system to overcome the current limitations is also described, as well as both the conventional and artificial intelligence solutions developed in SHARP.

SHARPs - A Near-Real-Time Space Weather Data Product from HMI

NASA Astrophysics Data System (ADS)

Bobra, M.; Turmon, M.; Baldner, C.; Sun, X.; Hoeksema, J. T.

2012-12-01

A data product from the Helioseismic and Magnetic Imager (HMI) on the Solar Dynamics Observatory (SDO), called Space-weather HMI Active Region Patches (SHARPs), is now available through the SDO Joint Science Operations Center (JSOC) and the Virtual Solar Observatory. SHARPs are magnetically active regions identified on the solar disk and tracked automatically in time. SHARP data are processed within a few hours of the observation time. The SHARP data series contains active region-sized disambiguated vector magnetic field data in both Lambert Cylindrical Equal-Area and CCD coordinates on a 12 minute cadence. The series also provides simultaneous HMI maps of the line-of-sight magnetic field, continuum intensity, and velocity on the same ~0.5 arc-second pixel grid. In addition, the SHARP data series provides space weather quantities computed on the inverted, disambiguated, and remapped data. The values for each tracked region are computed and updated in near real time. We present space weather results for several X-class flares; furthermore, we compare said space weather quantities with helioseismic quantities calculated using ring-diagram analysis.

SHARP: A multi-mission AI system for spacecraft telemetry monitoring and diagnosis

NASA Technical Reports Server (NTRS)

Lawson, Denise L.; James, Mark L.

1989-01-01

The Spacecraft Health Automated Reasoning Prototype (SHARP) is a system designed to demonstrate automated health and status analysis for multi-mission spacecraft and ground data systems operations. Telecommunications link analysis of the Voyager II spacecraft is the initial focus for the SHARP system demonstration which will occur during Voyager's encounter with the planet Neptune in August, 1989, in parallel with real-time Voyager operations. The SHARP system combines conventional computer science methodologies with artificial intelligence techniques to produce an effective method for detecting and analyzing potential spacecraft and ground systems problems. The system performs real-time analysis of spacecraft and other related telemetry, and is also capable of examining data in historical context. A brief introduction is given to the spacecraft and ground systems monitoring process at the Jet Propulsion Laboratory. The current method of operation for monitoring the Voyager Telecommunications subsystem is described, and the difficulties associated with the existing technology are highlighted. The approach taken in the SHARP system to overcome the current limitations is also described, as well as both the conventional and artificial intelligence solutions developed in SHARP.

Water-quality monitoring of Sweetwater Reservoir

USGS Publications Warehouse

Majewski, Michael

2001-01-01

Sweetwater Authority is concerned with the quality of water it provides to its customers. Results from the water-quality monitoring study that the USGS is conducting in the Sweetwater watershed show that the contaminant concentrations in bed sediments, water, and air are reflected in increased urbanization. The bed sediments show the most dramatic evidence of this impact with a sharp increase of persistent organic chemical concentrations over the past 65 years. Water quality is also affected by urbanization in the form of chemicals in the runoff water and deposition of airborne chemicals. The concentrations of the detected organic chemicals in Sweetwater and Loveland Reservoirs are all well below the guidance limits set by State and Federal agencies to protect human health. Many of these compounds are detected only because of the sensitive analytical methods used. This monitoring program provides the Sweetwater Authority with information on what monitored chemicals are present in the reservoirs, and at what concentrations. With this information, the Authority can assess the associated risks, and consider future water treatment and remediation. These results also help focus and support future efforts by Sweetwater Authority to protect the watershed.

Effect of molecular weight of starch on the properties of cassava starch microspheres prepared in aqueous two-phase system.

PubMed

Xia, Huiping; Li, Bing-Zheng; Gao, Qunyu

2017-12-01

Starch microspheres (SMs) were fabricated in an aqueous two-phase system (ATPS). A series of starch samples with different molecular weight were prepared by acid hydrolysis, and the effect of molecular weight of starch on the fabrication of SMs were investigated. Scanning electron microscopy (SEM) showed that the morphologies of SMs varied with starch molecular weight, and spherical SMs with sharp contours were obtained while using starch samples with weight-average molecular weight (M¯w)≤1.057×10 5 g/mol. X-ray diffraction (XRD) results revealed that crystalline structure of SMs were different from that of native cassava starch, and the relative crystallinity of SMs increased with the molecular weight of starch decreasing. Differential scanning calorimetry (DSC) results showed peak gelatinization temperature (T p ) and enthalpy of gelatinization (ΔH) of SMs increased with decreased M¯wof starch. Stability tests indicated that the SMs were stable under acid environment, but not stable under α-amylase hydrolysis. Copyright © 2017. Published by Elsevier Ltd.

Possible role of substance P in the ischemia-reperfusion injury in the isolated rabbit lung.

PubMed

Arreola, José L; Vargas, Mario H; Segura, Patricia; Chávez, Jaime; Sommer, Bettina; Carvajal, Verónica; Montaño, Luis M

2004-07-27

The origin of the endothelial damage leading to the ischemia-reperfusion injury after lung transplantation has not been elucidated. We postulated that neurotransmitters released during the preservation of the donor lung might explain this vascular derangement. Thus, in isolated rabbit lungs preserved over 24 hours, we evaluated the release of acetylcholine (ACh) and substance P (SP), the activity of their major degrading enzymes, acetylcholinesterase (AChE) and neutral endopeptidase (NEP), and changes in the capillary permeability. Both neurotransmitters showed the highest release rate in the first 15 minutes, followed by a sharp exponential decrement at 1, 6, 12 and 24 hours. AChE and NEP activities showed no variation at these time intervals. Basal capillary permeability significantly increased (P<0.01) after 24 hours preservation with saline. This increased permeability was avoided (P<0.01) by the SP fragment 4-11 (an SP receptors antagonist), but not by atropine. These results suggest for the first time a pathogenic role of SP in the ischemia-reperfusion injury, and thus the potential usefulness of SP antagonists as additives in the lung preservation solutions should be explored.

A 3D-Printable Polymer-Metal Soft-Magnetic Functional Composite-Development and Characterization.

PubMed

Khatri, Bilal; Lappe, Karl; Noetzel, Dorit; Pursche, Kilian; Hanemann, Thomas

2018-01-25

In this work, a 3D printed polymer-metal soft-magnetic composite was developed and characterized for its material, structural, and functional properties. The material comprises acrylonitrile butadiene styrene (ABS) as the polymer matrix, with up to 40 vol. % stainless steel micropowder as the filler. The composites were rheologically analyzed and 3D printed into tensile and flexural test specimens using a commercial desktop 3D printer. Mechanical characterization revealed a linearly decreasing trend of the ultimate tensile strength (UTS) and a sharp decrease in Young's modulus with increasing filler content. Four-point bending analysis showed a decrease of up to 70% in the flexural strength of the composite and up to a two-factor increase in the secant modulus of elasticity. Magnetic hysteresis characterization revealed retentivities of up to 15.6 mT and coercive forces of up to 4.31 kA/m at an applied magnetic field of 485 kA/m. The composite shows promise as a material for the additive manufacturing of passive magnetic sensors and/or actuators.

A 3D-Printable Polymer-Metal Soft-Magnetic Functional Composite—Development and Characterization

PubMed Central

Lappe, Karl; Noetzel, Dorit; Pursche, Kilian; Hanemann, Thomas

2018-01-01

In this work, a 3D printed polymer–metal soft-magnetic composite was developed and characterized for its material, structural, and functional properties. The material comprises acrylonitrile butadiene styrene (ABS) as the polymer matrix, with up to 40 vol. % stainless steel micropowder as the filler. The composites were rheologically analyzed and 3D printed into tensile and flexural test specimens using a commercial desktop 3D printer. Mechanical characterization revealed a linearly decreasing trend of the ultimate tensile strength (UTS) and a sharp decrease in Young’s modulus with increasing filler content. Four-point bending analysis showed a decrease of up to 70% in the flexural strength of the composite and up to a two-factor increase in the secant modulus of elasticity. Magnetic hysteresis characterization revealed retentivities of up to 15.6 mT and coercive forces of up to 4.31 kA/m at an applied magnetic field of 485 kA/m. The composite shows promise as a material for the additive manufacturing of passive magnetic sensors and/or actuators. PMID:29370112

Detection of blunt, sharp force and gunshot lesions on burnt remains: a cautionary note.

PubMed

Poppa, Pasquale; Porta, Davide; Gibelli, Daniele; Mazzucchi, Alessandra; Brandone, Alberto; Grandi, Marco; Cattaneo, Cristina

2011-09-01

The study of skin and bone lesions may give information concerning type and manner of production, but in burnt material modification of tissues by the high temperatures may considerably change the morphological characteristics of the lesions. This study aims at pointing out the effects of burning head of pigs with several types of lesions (blunt trauma, sharp force, and gunshot lesions) on soft tissues and bones, both from a morphological and chemical point of view. Results show that the charring process does not completely destroy signs of lesions on bones, which can often be recovered by cleaning bone surface from charred soft-tissue residues. Furthermore, neutron activation analysis test proved that antimony may be detectable also on gunshot entry wounds at the final stages of charring process.

Farewell to Murray Buttes Image 3

NASA Image and Video Library

2016-09-09

This view from the Mast Camera (Mastcam) in NASA's Curiosity Mars rover shows finely layered rocks within the "Murray Buttes" region on lower Mount Sharp. The buttes and mesas rising above the surface in this area are eroded remnants of ancient sandstone that originated when winds deposited sand after lower Mount Sharp had formed. Curiosity closely examined that layer -- called the "Stimson formation" -- during the first half of 2016, while crossing a feature called "Naukluft Plateau" between two exposures of the Murray formation. The layering within the sandstone is called "cross-bedding" and indicates that the sandstone was deposited by wind as migrating sand dunes. The image was taken on Sept. 8, 2016, during the 1454th Martian day, or sol, of Curiosity's work on Mars. http://photojournal.jpl.nasa.gov/catalog/PIA21043

Farewell to Murray Buttes Image 2

NASA Image and Video Library

2016-09-09

This view from the Mast Camera (Mastcam) in NASA's Curiosity Mars rover shows sloping buttes and layered outcrops within the "Murray Buttes" region on lower Mount Sharp. The buttes and mesas rising above the surface are eroded remnants of ancient sandstone that originated when winds deposited sand after lower Mount Sharp had formed. Curiosity closely examined that layer -- called the "Stimson formation" -- during the first half of 2016, while crossing a feature called "Naukluft Plateau" between two exposures of the Murray formation. The layering within the sandstone is called "cross-bedding" and indicates that the sandstone was deposited by wind as migrating sand dunes. The image was taken on Sept. 8, 2016, during the 1454th Martian day, or sol, of Curiosity's work on Mars. http://photojournal.jpl.nasa.gov/catalog/PIA21042

Farewell to Murray Buttes Image 4

NASA Image and Video Library

2016-09-09

This view from the Mast Camera (Mastcam) in NASA's Curiosity Mars rover shows an outcrop with finely layered rocks within the "Murray Buttes" region on lower Mount Sharp. The buttes and mesas rising above the surface in this area are eroded remnants of ancient sandstone that originated when winds deposited sand after lower Mount Sharp had formed. Curiosity closely examined that layer -- called the "Stimson formation" -- during the first half of 2016, while crossing a feature called "Naukluft Plateau" between two exposures of the Murray formation. The layering within the sandstone is called "cross-bedding" and indicates that the sandstone was deposited by wind as migrating sand dunes. The image was taken on Sept. 8, 2016, during the 1454th Martian day, or sol, of Curiosity's work on Mars. http://photojournal.jpl.nasa.gov/catalog/PIA21044

Farewell to Murray Buttes Image 5

NASA Image and Video Library

2016-09-09

This view from the Mast Camera (Mastcam) in NASA's Curiosity Mars rover shows a hillside outcrop with layered rocks within the "Murray Buttes" region on lower Mount Sharp. The buttes and mesas rising above the surface in this area are eroded remnants of ancient sandstone that originated when winds deposited sand after lower Mount Sharp had formed. Curiosity closely examined that layer -- called the "Stimson formation" -- during the first half of 2016, while crossing a feature called "Naukluft Plateau" between two exposures of the Murray formation. The layering within the sandstone is called "cross-bedding" and indicates that the sandstone was deposited by wind as migrating sand dunes. The image was taken on Sept. 8, 2016, during the 1454th Martian day, or sol, of Curiosity's work on Mars. http://photojournal.jpl.nasa.gov/catalog/PIA21045

STS-42 Earth observation of the Rhone River / Lake Geneva in Switzerland

NASA Technical Reports Server (NTRS)

1992-01-01

STS-42 Earth observation taken aboard Discovery, Orbiter Vehicle (OV) 103, shows the Rhone River flowing into Lake Geneva in western Switzerland (46.0N, 7.0E). The sharp change in the valley's orientation is a feature of this view. Several times during cold periods of the Earth's history (the geologically recent Ice Ages of the last 1.5 million years or so), this valley has been filled with ice flowing off the mountain ranges. Ice erosion has widened and lowered the valley. The surrounding mountain chains include the highest peak in Europe, Mont Blanc (15,781 feet) on the French-Italian border, and the well-known Matterhorn (14,130) feet on the Swiss-Italian border. Ice-sculpting has generated the characteristically sharp ridges and pointed peaks of the Alps.

Curiosity Destinations for Second Extended Mission

NASA Image and Video Library

2016-10-03

This map shows the route driven by NASA's Curiosity Mars rover from the location where it landed in August 2012 to its location in September 2016 at "Murray Buttes," and the path planned for reaching destinations at "Hematite Unit" and "Clay Unit" on lower Mount Sharp. Blue triangles mark waypoints investigated by Curiosity during the rover's two-year prime mission and first two-year extended mission. The Hematite Unit and Clay Unit are key destinations for the second two-year extension, through September 2018. The base image for the map is from the High Resolution Imaging Science Experiment (HiRISE) camera on NASA's Mars Reconnaissance Orbiter. North is up. Bagnold Dunes form a band of dark, wind-blown material at the foot of Mount Sharp. http://photojournal.jpl.nasa.gov/catalog/PIA20846

Subatomic electronic feature from dynamic motion of Si dimer defects in Bi nanolines on Si(001)

NASA Astrophysics Data System (ADS)

Kirkham, C. J.; Longobardi, M.; Köster, S. A.; Renner, Ch.; Bowler, D. R.

2017-08-01

Scanning tunneling microscopy (STM) reveals unusual sharp features in otherwise defect-free Bi nanolines self-assembled on Si(001). They appear as subatomic thin lines perpendicular to the Bi nanoline at positive biases and as atomic size beads at negative biases. Density functional theory (DFT) simulations show that these features can be attributed to buckled Si dimers substituting for Bi dimers in the nanoline, where the sharp feature is the counterintuitive signature of these dimers flipping during scanning. The perfect correspondence between the STM data and the DFT simulation demonstrated in this paper highlights the detailed understanding we have of the complex Bi-Si(001) Haiku system. This discovery has applications in the patterning of Si dangling bonds for nanoscale electronics.

[Klinefelter's syndrome associated with mixed connective tissue disease (Sharp's syndrome) and thrombophilia with postthrombotic syndrome].

PubMed

Kasten, Robert; Pfirrmann, Gudrun; Voigtländer, Volker

2005-08-01

A 43-year-old male with eunuchoid body proportions and a history of deep venous thromboses in the right leg presented with recurrent ulcers in the right perimalleolar region for 6 years. Karyotyping revealed a 47 XXY Klinefelter's syndrome, while serologic testing showed protein S deficiency, hyperhomocysteinemia and positive lupus anticoagulant. He also had mixed connective tissue disease (Sharp's syndrome) with acrosclerosis, proximal finger edema, Raynaud's phenomenon, and high titers of ANA and U1-RNP-antibodies, as well as osteoporosis. There is evidence that patients with Klinefelter's syndrome are prone to develop connective tissue diseases and thrombophilia as a result of low androgen levels. Substitution of testosterone in Klinefelter's syndrome can have a favorable therapeutic effect on the associated connective tissue disease, thrombophilia and osteoporosis.

Solving intraocular lens-related pigment dispersion syndrome with repositioning of primary sulcus implanted single-piece IOL in the capsular bag.

PubMed

Kohnen, Thomas; Kook, Daniel

2009-08-01

We describe 2 cases of pigment dispersion syndrome (PDS) after uneventful phacoemulsification and implantation of a posterior chamber single-piece intraocular lens (IOL) with a sharp-edge design. In both cases, several days after IOL implantation, marked pigment dispersion was seen on the iris and in the trabecular meshwork, associated with an elevation in intraocular pressure (IOP). Thorough examination showed that the implanted IOL was in the ciliary sulcus. After surgical repositioning of both IOLs in the capsular bag, the pigment dispersion regressed and the IOP returned to normal limits. The 2 cases suggest that particularly in PDS patients, an IOL with an anterior sharp-edge design should be implanted in the capsular bag. Implantation in the ciliary sulcus should be avoided.

Sharp bounds for singular values of fractional integral operators

NASA Astrophysics Data System (ADS)

Burman, Prabir

2007-03-01

From the results of Dostanic [M.R. Dostanic, Asymptotic behavior of the singular values of fractional integral operators, J. Math. Anal. Appl. 175 (1993) 380-391] and Vu and Gorenflo [Kim Tuan Vu, R. Gorenflo, Singular values of fractional and Volterra integral operators, in: Inverse Problems and Applications to Geophysics, Industry, Medicine and Technology, Ho Chi Minh City, 1995, Ho Chi Minh City Math. Soc., Ho Chi Minh City, 1995, pp. 174-185] it is known that the jth singular value of the fractional integral operator of order [alpha]>0 is approximately ([pi]j)-[alpha] for all large j. In this note we refine this result by obtaining sharp bounds for the singular values and use these bounds to show that the jth singular value is ([pi]j)-[alpha][1+O(j-1)].

Image quality evaluation for smart-phone displays at lighting levels of indoor and outdoor conditions

NASA Astrophysics Data System (ADS)

Gong, Rui; Xu, Haisong; Wang, Binyu; Luo, Ming Ronnier

2012-08-01

The image quality of two active matrix organic light emitting diode (AMOLED) smart-phone displays and two in-plane switching (IPS) ones was visually assessed at two levels of ambient lighting conditions corresponding to indoor and outdoor applications, respectively. Naturalness, colorfulness, brightness, contrast, sharpness, and overall image quality were evaluated via psychophysical experiment by categorical judgment method using test images selected from different application categories. The experimental results show that the AMOLED displays perform better on colorfulness because of their wide color gamut, while the high pixel resolution and high peak luminance of the IPS panels help the perception of brightness, contrast, and sharpness. Further statistical analysis of ANOVA indicates that ambient lighting levels have significant influences on the attributes of brightness and contrast.

Aspect-ratio dependence of magnetization reversal in cylindrical ferromagnetic nanowires

NASA Astrophysics Data System (ADS)

Sultan, Musaab S.; Atkinson, Del

2016-05-01

The magnetization reversal behavior in isolated cylindrical and square cross-section Ni81Fe19 nanowires was systematically studied as a function of nanowire cross-section dimensions from 10 up to 200 nm using micromagnetic simulations. This approach provides access to the switching field, remanence ratio and most significantly the magnetization structures during reversal, which allows the evolution of magnetization processes to be studied with scaling of the cross-sectional dimensions. The dimensional trends in reversal behavior for both square and circular cross-section were comparable throughout the range of dimensions studied. The thinnest nanowires showed simple square switching and 100% remanence. With increasing diameter the switching field reduces and above 40 nm the reversal behavior shows an increasing rotational component prior to sharp switching of the magnetization. The magnitude of the reversible component increases with increasing dimensions up to 150 nm, above which the magnetization reversal process is more complicated and the hysteresis loops are no longer bistable. The micromagnetic structures evolve from simple uniform parallel single domain states in the thinnest wires through the formation of vortex-like end states in thicker wires to complex multidomain structures during the reversal of the thickest wires. In the later cases the reversal is not simple curling-like behavior, although the angular switching field dependence was comparable with curling.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Demirbas, A.; Simsek, T.

In this work, the utilization of aniline (C{sub 6}H{sub 7}N) formaldehyde (HCHO) resins as a binding agent of coke briquetting was investigated. Aniline (AN) formaldehyde (F) resins are a family of thermoplastics synthesized by condensing AN and F in an acid solution exhibiting high dielectric strength. The tensile strength sharply increases as the ratio of F to AN from 0.5 to 1.6, and it reaches the highest values between 1.6 and 2.2 F/AN ratio; it then slightly decreases. The highest tensile strength of F-AN resin-coke briquette (23.66 MN/m{sup 2}) was obtained from the run with 1.5 of F/AN ratio bymore » using (NH4){sub 2}S{sub 2}O{sub 8} catalyst at 310 K briquetting temperature. The tensile strength of F-AN resin-coke briquette slightly decreased with increasing the catalyst percent to 0.10%, and then it sharply decreased to zero with increasing the catalyst percent to 0.2%. The effect of pH on the tensile strength is irregular. As the pH of the mixture increases from 9.0 to 9.2, the tensile strength shows a sharp increase, and the curve reaches a plateau value between pH 9.3 and 9.9; then the tensile strength shows a slight increase after pH = 9.9.« less

Vibrational dynamics and boson peak in a supercooled polydisperse liquid.

PubMed

Abraham, Sneha Elizabeth; Bagchi, Biman

2010-03-01

Vibrational density of states (VDOS) in a supercooled polydisperse liquid is computed by diagonalizing the Hessian matrix evaluated at the potential energy minima for systems with different values of polydispersity. An increase in polydispersity leads to an increase in the relative population of localized high-frequency modes. At low frequencies, the density of states shows an excess compared to the Debye squared-frequency law, which has been identified with the boson peak. The height of the boson peak increases with polydispersity and shows a rather narrow sensitivity to changes in temperature. While the modes comprising the boson peak appear to be largely delocalized, there is a sharp drop in the participation ratio of the modes that exist just below the boson peak indicative of the quasilocalized nature of the low-frequency vibrations. Study of the difference spectrum at two different polydispersity reveals that the increase in the height of boson peak is due to a population shift from modes with frequencies above the maximum in the VDOS to that below the maximum, indicating an increase in the fraction of the unstable modes in the system. The latter is further supported by the facilitation of the observed dynamics by polydispersity. Since the strength of the liquid increases with polydispersity, the present result provides an evidence that the intensity of boson peak correlates positively with the strength of the liquid, as observed earlier in many experimental systems.

Fluid thermodynamics control thermal weakening during earthquake rupture.

NASA Astrophysics Data System (ADS)

Acosta, M.; Passelegue, F. X.; Schubnel, A.; Violay, M.

2017-12-01

Although fluids are pervasive among tectonic faults, thermo-hydro-mechanical couplings during earthquake slip remain unclear. We report full dynamic records of stick-slip events, performed on saw cut Westerly Granite samples loaded under triaxial conditions at stresses representative of the upper continental crust (σ3' 70 MPa) Three fluid pressure conditions were tested, dry, low , and high pressure (i.e. Pf=0, 1, and 25 MPa). Friction (μ) evolution recorded at 10 MHz sampling frequency showed that, for a single event, μ initially increased from its static pre-stress level, μ0 to a peak value μ p it then abruptly dropped to a minimum dynamic value μd before recovering to its residual value μr, where the fault reloaded elastically. Under dry and low fluid pressure conditions, dynamic friction (μd) was extremely low ( 0.2) and co-seismic slip (δ) was large ( 250 and 200 μm respectively) due to flash heating (FH) and melting of asperities as supported by microstructures. Conversely, at pf=25 MPa, μd was higher ( 0.45), δ was smaller ( 80 μm), and frictional melting was not found. We calculated flash temperatures at asperity contacts including heat buffering by on-fault fluid. Considering the isobaric evolution of water's thermodynamic properties with rising temperature showed that pressurized water controlled fault heating and weakening, through sharp variations of specific heat (cpw) and density (ρw) at water's phase transitions. Injecting the computed flash temperatures into slip-on-a-plane model for thermal pressurization (TP) showed that: (i) if pf was low enough so that frictional heating induced liquid/vapour phase transition, FH operated, allowing very low μd during earthquakes. (ii) Conversely, if pf was high enough that shear heating induced a sharp phase transition directly from liquid to supercritical state, an extraordinary rise in water's specific heat acted as a major energy sink inhibiting FH and limiting TP, allowing higher dynamic fault strengths. Further extrapolation of this simplified model to mid- and low- crustal depths shows that, large cpw rise during phase transitions makes TP the dominant weakening mechanism up to 5 km depth. Increasing depth allows somewhat larger shear stress and reduced cpw rise, and so substantial shear heating at low slip rates, favouring FH for fault weakening.

Technology of welding aluminum alloys-I

NASA Technical Reports Server (NTRS)

Harrison, J. R.; Korb, L. J.; Oleksiak, C. E.

1978-01-01

Systems approach to high-quality aluminum welding uses square-butt joints, kept away from sharp contour changes. Intersecting welds are configured for T-type intersections rather than crossovers. Differences in panel thickness are accommodated with transition step areas where thickness increases or decreases within weld, but never at intersection.

Hispanic Outreach: Delivering the Safety and Health Message.

ERIC Educational Resources Information Center

Delaney, Kathryn

2002-01-01

After a sharp increase in fatal accidents among Hispanic construction workers in Dallas, the Occupational Safety and Health Administration (OSHA) began aggressive outreach to the Mexican American community. Efforts included training bilingual safety trainers, offering workers' safety training in Spanish, and developing Spanish-language materials.…

CHARACTERIZATION AND REDUCTION OF FORMALDEHYDE EMISSIONS FROM A LOW-VOC LATEX PAINT

EPA Science Inventory

The patterns of formaldehyde emission from a low volatile organic compound (VOC) latex paint applied to gypsum board were measured and analyzed by small environmental chamber tests. It was found that the formaldehyde emissions resulted in sharp increase of chamber air formaldehy...

Evaluating Continuing Education Needs and Program Effectiveness Using a Survey of Virginia's SHARP Logger Program Participants

ERIC Educational Resources Information Center

Barrett, Scott M.; Bolding, M. Chad; Munsell, John F.

2012-01-01

Virginia's SHARP logger program is a Cooperative Extension program currently providing training to over 1,500 loggers, foresters, and others. We conducted a mail survey of SHARP loggers to characterize program participants, assess programming needs, and evaluate program effectiveness. Results indicate a diverse group of participants in terms of…

78 FR 59425 - Proposed Collection: Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-26

... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... Service, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov... INFORMATION CONTACT: Requests for additional information or copies should be directed to Bruce A. Sharp...

77 FR 13176 - Proposed Collection: Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-05

... 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the Department of the.... Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity...: Requests for additional information or copies should be directed to Bruce A. Sharp, Bureau of the Public...

77 FR 31689 - Proposed Information Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-29

... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the.... Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity...: Requests for additional information or copies should be directed to Bruce A. Sharp, Bureau of the Public...

77 FR 32179 - Proposed Collection: Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-31

... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently the.... Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity...: Requests for additional information or copies should be directed to Bruce A. Sharp, Bureau of the Public...

78 FR 21706 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-11

... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas... INFORMATION CONTACT: Requests for additional information or copies should be directed to Bruce A. Sharp...

77 FR 60026 - Proposed Collection: Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-01

... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas... INFORMATION CONTACT: Requests for additional information or copies should be directed to Bruce A. Sharp...

77 FR 19424 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-30

..., as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A..., Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The...: Requests for additional information or copies should be directed to Bruce A. Sharp, Bureau of the Public...

77 FR 32180 - Proposed Collection: Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-31

... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd... INFORMATION CONTACT: Requests for additional information or copies should be directed to Bruce A. Sharp...

A study of the depth and size of concave cube Au nanoparticles as highly sensitive SERS probes

NASA Astrophysics Data System (ADS)

Romo-Herrera, J. M.; González, A. L.; Guerrini, L.; Castiello, F. R.; Alonso-Nuñez, G.; Contreras, O. E.; Alvarez-Puebla, R. A.

2016-03-01

High and uniform near fields are localized at the eight similar sharp corners of cubic gold nanoparticles. Moreover, by introducing concavity in the particle lateral planes, such field intensities can be further increased and tuned in the near infrared region without altering the overall size of the nanoparticles. Herein, we perform a thorough investigation of the morphological, crystallographic and plasmonic properties of concave gold nanocubes (GNCs) in the sub-70 nm size range, for their potential application as highly efficient SERS substrates in size-limiting cases. Theoretical calculations indicate that the highest increment of the near-field is located at the eight sharp tips and, interestingly, a medium near-field increment is also activated over the volume next to the concave surface. Remarkably, the plasmonic response of the concave cubic morphology showed great sensitivity to the concavity degree. Experimental SERS analysis nicely matches the outcome of the theoretical model, confirming that medium-sized concave GNCs (35 nm side length) possess the highest SERS activity upon excitation with a 633 nm laser, whereas larger 61 nm side concave GNCs dominate the optical response at 785 nm. Due to their size-intensity trade off, we envision that such small concave gold nanocubes can provide a highly active and efficient SERS platform for size-limiting applications, especially when near infrared excitations are required.High and uniform near fields are localized at the eight similar sharp corners of cubic gold nanoparticles. Moreover, by introducing concavity in the particle lateral planes, such field intensities can be further increased and tuned in the near infrared region without altering the overall size of the nanoparticles. Herein, we perform a thorough investigation of the morphological, crystallographic and plasmonic properties of concave gold nanocubes (GNCs) in the sub-70 nm size range, for their potential application as highly efficient SERS substrates in size-limiting cases. Theoretical calculations indicate that the highest increment of the near-field is located at the eight sharp tips and, interestingly, a medium near-field increment is also activated over the volume next to the concave surface. Remarkably, the plasmonic response of the concave cubic morphology showed great sensitivity to the concavity degree. Experimental SERS analysis nicely matches the outcome of the theoretical model, confirming that medium-sized concave GNCs (35 nm side length) possess the highest SERS activity upon excitation with a 633 nm laser, whereas larger 61 nm side concave GNCs dominate the optical response at 785 nm. Due to their size-intensity trade off, we envision that such small concave gold nanocubes can provide a highly active and efficient SERS platform for size-limiting applications, especially when near infrared excitations are required. Electronic supplementary information (ESI) available: Nanoparticle size distribution analysis (Fig. SI-1); extended TEM analysis on nanocubes morphology (Fig. SI-2, SI-3 and SI-4); comparison of GNCs size and concavity degree (Fig. SI-4); optical response calculations using the curved edges model (Fig. SI-5); simulated optical absorption spectra as a function of the concavity depth (Fig. SI-6); background SERS spectrum (Fig. SI-8) and details on the calculation of the SERS enhancement factors. See DOI: 10.1039/c6nr01155a

Marked surface inversions and wind shear: A safety risk for departing aircraft

NASA Technical Reports Server (NTRS)

Korhonen, O.

1983-01-01

Marked surface inversions occur most frequently in dry continental climates, where low atmospheric humidity allows heat transfer by long wave thermal radiation. In the northern latitudes, surface inversions reach their maximum intensity during the winter, when the incoming Sun's radiation is negligible and radiative cooling is dominant during the long nights. During winter, air mass boundaries are sharp, which causes formation of marked surface inversions. The existence of these inversions and sharp boundaries increase the risk of wind shear. The information should refer to marked inversions exceeding a temperature difference of 10 deg C up to 1000 feet. The need to determine the temperature range over which he information is operationally needed and the magnitude of the inversion required before a notification to pilots prior to departure is warranted are outlined.

Laser ablated hard coating for microtools

DOEpatents

McLean, II, William; Balooch, Mehdi; Siekhaus, Wigbert J.

1998-05-05

Wear-resistant coatings composed of laser ablated hard carbon films, are deposited by pulsed laser ablation using visible light, on instruments such as microscope tips and micro-surgical tools. Hard carbon, known as diamond-like carbon (DLC), films produced by pulsed laser ablation using visible light enhances the abrasion resistance, wear characteristics, and lifetimes of small tools or instruments, such as small, sharp silicon tips used in atomic probe microscopy without significantly affecting the sharpness or size of these devices. For example, a 10-20 nm layer of diamond-like carbon on a standard silicon atomic force microscope (AFM) tip, enables the useful operating life of the tip to be increased by at least twofold. Moreover, the low inherent friction coefficient of the DLC coating leads to higher resolution for AFM tips operating in the contact mode.

The cutoff phenomenon in finite Markov chains.

PubMed Central

Diaconis, P

1996-01-01

Natural mixing processes modeled by Markov chains often show a sharp cutoff in their convergence to long-time behavior. This paper presents problems where the cutoff can be proved (card shuffling, the Ehrenfests' urn). It shows that chains with polynomial growth (drunkard's walk) do not show cutoffs. The best general understanding of such cutoffs (high multiplicity of second eigenvalues due to symmetry) is explored. Examples are given where the symmetry is broken but the cutoff phenomenon persists. PMID:11607633

The Formation and Erosion History of Mt. Sharp

NASA Technical Reports Server (NTRS)

Allen, Carlton C.; Dapremont, Angela M.

2014-01-01

The Curiosity rover is exploring 155 km diameter Gale crater and Mt. Sharp, Gale's 5 km high central mound (Fig. 1). This study addresses the formation and erosion history of Mt. Sharp. Gale lies on the topographic dichotomy between the southern highlands and the northern plains - a drop of over 2 km [1,2]. Altitude differences between the north and south rim reflect this regional slope, as do altitude differences between the deep annulus north of Mt. Sharp and the southern crater floor. Orbiter and rover images demonstrate that most exposed areas on Mt. Sharp consist of thin, sub-parallel units interpreted as sedimentary layers [3]. Gale is typical of the 50 large martian craters that have been totally or partially filled with such layers [4,5]. In many craters these sediments have been deeply eroded. Central Peak and Peak Ring: The highest point on Mt. Sharp, near the crater's center, is interpreted as a central peak [6]. The peak has a massive lower portion and a thin, smooth capping deposit (Fig. 2). Gale's size is transitional between martian craters with single central peaks and craters with peak rings approximately half the crater's diameter [2,6]. The boundaries of Mt. Sharp, as well as an arc of hills to the southeast of the mountain, closely match a circle approximately 80 km in diameter (Fig. 3). This morphology suggests that the Gale impact may have formed both a central peak and a partial peak ring, which is covered by the sediments of Mt. Sharp in the north and possibly exposed in the arc of eroded hills in the southeast quadrant (Figs. 3,4).

A comprehensive numerical analysis of background phase correction with V-SHARP.

PubMed

Özbay, Pinar Senay; Deistung, Andreas; Feng, Xiang; Nanz, Daniel; Reichenbach, Jürgen Rainer; Schweser, Ferdinand

2017-04-01

Sophisticated harmonic artifact reduction for phase data (SHARP) is a method to remove background field contributions in MRI phase images, which is an essential processing step for quantitative susceptibility mapping (QSM). To perform SHARP, a spherical kernel radius and a regularization parameter need to be defined. In this study, we carried out an extensive analysis of the effect of these two parameters on the corrected phase images and on the reconstructed susceptibility maps. As a result of the dependence of the parameters on acquisition and processing characteristics, we propose a new SHARP scheme with generalized parameters. The new SHARP scheme uses a high-pass filtering approach to define the regularization parameter. We employed the variable-kernel SHARP (V-SHARP) approach, using different maximum radii (R m ) between 1 and 15 mm and varying regularization parameters (f) in a numerical brain model. The local root-mean-square error (RMSE) between the ground-truth, background-corrected field map and the results from SHARP decreased towards the center of the brain. RMSE of susceptibility maps calculated with a spatial domain algorithm was smallest for R m between 6 and 10 mm and f between 0 and 0.01 mm -1 , and for maps calculated with a Fourier domain algorithm for R m between 10 and 15 mm and f between 0 and 0.0091 mm -1 . We demonstrated and confirmed the new parameter scheme in vivo. The novel regularization scheme allows the use of the same regularization parameter irrespective of other imaging parameters, such as image resolution. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Understanding the Hospital Sharps Injury Reporting Pathway

PubMed Central

Boden, Leslie I.; Petrofsky, Yolanta V.; Hopcia, Karen; Wagner, Gregory R.; Hashimoto, Dean

2016-01-01

Introduction Patient-care workers are frequently exposed to sharps injuries, which can involve the risk of serious illness. Underreporting of these injuries can compromise prevention efforts. Materials and Methods We linked survey responses of 1572 non-physician patient-care workers with the Occupational Health Services (OHS) database at two academic hospitals. We determined whether survey respondents who said they had sharps injuries indicated that they had reported them and whether reported injuries were recorded in the OHS database. Results Respondents said that they reported 62 of 78 sharps injuries occurring over a 12-month period. Only 28 appeared in the OHS data. Safety practices were positively associated with respondents’ saying they reported sharps injuries but not with whether reported injuries appeared in the OHS data. Conclusions Administrators should consider creating reporting mechanisms that are simpler and more direct. Administrators and researchers should attempt to understand how incidents might be lost before they are recorded. PMID:25308763

Head CT: Image quality improvement with ASIR-V using a reduced radiation dose protocol for children.

PubMed

Kim, Hyun Gi; Lee, Ho-Joon; Lee, Seung-Koo; Kim, Hyun Ji; Kim, Myung-Joon

2017-09-01

To investigate the quality of images reconstructed with adaptive statistical iterative reconstruction V (ASIR-V), using pediatric head CT protocols. A phantom was scanned at decreasing 20% mA intervals using our standard pediatric head CT protocols. Each study was then reconstructed at 10% ASIR-V intervals. After the phantom study, we reduced mA by 10% in the protocol for <3-year-old patients and applied 30% ASIR-V and by 30% in the protocol for 3- to 15-year-old patients and applied 40% ASIR-V. Increasing the percentage of ASIR-V resulted in lower noise and higher contrast-to-noise ratio (CNR) and preserved spatial resolution in the phantom study. Compared to a conventional-protocol, reduced-dose protocol with ASIR-V achieved 12.8% to 34.0% of dose reduction and showed images of lower noise (9.22 vs. 10.73, P = 0.043) and higher CNR in different levels (centrum semiovale, 2.14 vs. 1.52, P = 0.003; basal ganglia, 1.46 vs. 1.07, P = 0.001; and cerebellum, 2.18 vs. 1.33, P < 0.001). Qualitative analysis showed higher gray-white matter differentiation and sharpness and preserved overall diagnostic quality in the images with ASIR-V. Use of ASIR-V allowed a 12.8% to 34.0% dose reduction in each age group with potential to improve image quality. • It is possible to reduce radiation dose and improve image quality with ASIR-V. • We improved noise and CNR and decreased radiation dose. • Sharpness improved with ASIR-V. • Total radiation dose was decreased by 12.8% to 34.0%.

Phase-field modeling of liquids splitting between separating surfaces and its application to high-resolution roll-based printing technologies

NASA Astrophysics Data System (ADS)

Hizir, F. E.; Hardt, D. E.

2017-05-01

An in-depth understanding of the liquid transport in roll-based printing systems is essential for advancing the roll-based printing technology and enhancing the performance of the printed products. In this study, phase-field simulations are performed to characterize the liquid transport in roll-based printing systems, and the phase-field method is shown to be an effective tool to simulate the liquid transport. In the phase-field simulations, the liquid transport through the ink transfer rollers is approximated as the stretching and splitting of liquid bridges with pinned or moving contact lines between vertically separating surfaces. First, the effect of the phase-field parameters and the mesh characteristics on the simulation results is examined. The simulation results show that a sharp interface limit is approached as the capillary width decreases while keeping the mobility proportional to the capillary width squared. Close to the sharp interface limit, the mobility changes over a specified range are observed to have no significant influence on the simulation results. Next, the ink transfer from the cells on the surface of an ink-metering roller to the surface of stamp features is simulated. Under negligible inertial effects and in the absence of gravity, the amount of liquid ink transferred from an axisymmetric cell with low surface wettability to a stamp with high surface wettability is found to increase as the cell sidewall steepness and the cell surface wettability decrease and the stamp surface wettability and the capillary number increase. Strategies for improving the resolution and quality of roll-based printing are derived based on an analysis of the simulation results. The application of novel materials that contain cells with irregular surface topography to stamp inking in high-resolution roll-based printing is assessed.