3. VIEW NORTH, SOUTHWEST FRONT, SOUTHEAST SIDE Front and side ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. VIEW NORTH, SOUTHWEST FRONT, SOUTHEAST SIDE Front and side elevation. Note gasoline sign post added. Flush store window not altered, 1900 clapboard siding and panelling remaining. - 510 Central Avenue (Commercial Building), Ridgely, Caroline County, MD

Efficacy of Intense Pulsed Light Therapy in the Treatment of Facial Acne Vulgaris: Comparison of Two Different Fluences

PubMed Central

Patidar, Monika V; Deshmukh, Ashish Ramchandra; Khedkar, Maruti Yadav

2016-01-01

Background: Acne vulgaris is the most common disease of the skin affecting adolescents and young adults causing psychological distress. The combination of antibiotic resistance, adverse effects of topical and systemic anti acne medications and desire for high tech approaches have all led to new enthusiasm for light based acne treatment. Intense pulse light (IPL) therapy has three modes of action in acne vulgaris i.e., photochemical, photo thermal and photo immunological. Aims: (1) to study efficacy of IPL therapy in facial acne vulgaris. (2) To compare two fluences - one normal and other subnormal on right and left side of face respectively. Methods: (Including settings and design and statistical analysis used). Total 45 patients in age group 16 to 28 years with inflammatory facial acne vulgaris were included in prospective study. Baseline data for each patient was recorded. All patients were given 4 sittings of IPL at 2 weeks interval and were followed for 2 months every 2 weeks. Fluence used was 35J/cm2 on right and 20J/cm2 on left side. Percentage reduction in lesion count was calculated at each sitting and follow up and graded as mild (0-25%), moderate (26-50%), good (51-75%) and excellent (76-100%). Side effects were noted. The results were analysed using Mann-Whitney Test. Results: On right side, excellent results were achieved in 10(22%), good in 22(49%) and moderate in 13(29%) patients. On left side excellent were results achieved in 7(15%), good in 19(42%) and moderate in 16(43%) patients. There was no statically significant difference noted in efficacy of two fluences used in treatment of facial acne vulgaris. Conclusions: IPL is a effective and safe option for inflammatory acne vulgaris with minimal reversible side effects. Subnormal fluence is as effective as normal fluence in Indian skin. PMID:27688446

Efficacy of Intense Pulsed Light Therapy in the Treatment of Facial Acne Vulgaris: Comparison of Two Different Fluences.

PubMed

Patidar, Monika V; Deshmukh, Ashish Ramchandra; Khedkar, Maruti Yadav

2016-01-01

Acne vulgaris is the most common disease of the skin affecting adolescents and young adults causing psychological distress. The combination of antibiotic resistance, adverse effects of topical and systemic anti acne medications and desire for high tech approaches have all led to new enthusiasm for light based acne treatment. Intense pulse light (IPL) therapy has three modes of action in acne vulgaris i.e., photochemical, photo thermal and photo immunological. (1) to study efficacy of IPL therapy in facial acne vulgaris. (2) To compare two fluences - one normal and other subnormal on right and left side of face respectively. (Including settings and design and statistical analysis used). Total 45 patients in age group 16 to 28 years with inflammatory facial acne vulgaris were included in prospective study. Baseline data for each patient was recorded. All patients were given 4 sittings of IPL at 2 weeks interval and were followed for 2 months every 2 weeks. Fluence used was 35J/cm(2) on right and 20J/cm(2) on left side. Percentage reduction in lesion count was calculated at each sitting and follow up and graded as mild (0-25%), moderate (26-50%), good (51-75%) and excellent (76-100%). Side effects were noted. The results were analysed using Mann-Whitney Test. On right side, excellent results were achieved in 10(22%), good in 22(49%) and moderate in 13(29%) patients. On left side excellent were results achieved in 7(15%), good in 19(42%) and moderate in 16(43%) patients. There was no statically significant difference noted in efficacy of two fluences used in treatment of facial acne vulgaris. IPL is a effective and safe option for inflammatory acne vulgaris with minimal reversible side effects. Subnormal fluence is as effective as normal fluence in Indian skin.

Effect of yaw angle on steering forces for the lunar roving vehicle wheel

NASA Technical Reports Server (NTRS)

Green, A. J.

1974-01-01

A series of tests was conducted with a Lunar Roving Vehicle (LRV) wheel operating at yaw angles ranging from -5 to +90 deg. The load was varied from 42 to 82 lb (187 to 365 N), and the speed was varied from 3.5 to 10.0 ft/sec (1.07 to 3.05 m/sec). It was noted that speed had an effect on side thrust and rut depth. Side thrust, rut depth, and skid generally increased as the yaw angle increased. For the range of loads used, the effect of load on performance was not significant.

5. SOUTH SIDE DRIVE AT CHAPEL STRAIGHT. NOTE BIKE PATH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. SOUTH SIDE DRIVE AT CHAPEL STRAIGHT. NOTE BIKE PATH AND BOULDER LANE EDGING. CHAPEL SPIRE AT CENTER. LOCATION OF OLD YOSEMITE VILLAGE AT CENTER DISTANCE. NORTH DOME AT REAR. LOOKING NNE. GIS: N-37 44 21.8 / W-119 35 39.3 - Yosemite National Park Roads & Bridges, Yosemite Village, Mariposa County, CA

Compartment A126 port side. Note ash hoist for boiler room ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Compartment A-126 port side. Note ash hoist for boiler room compartment B-1 and compartment B-2. Scuttlebutt (drinking water fountain) is at right center of photograph. Manikin wearing WWII wave uniform is in display case at left center. (045) - USS Olympia, Penn's Landing, 211 South Columbus Boulevard, Philadelphia, Philadelphia County, PA

Fire Protection of Large Air Force Hangars

DTIC Science & Technology

1975-10-01

Aqueous Film - Forming Foam ( AFFF ) in an environment...determining further the effectiveness of 3-percent aqueous film forming foam ( AFFF ); b) determining the effectiveness of AFFF systems at high ceiling...Id SUPPLEMENTARY NOTES 19. KEY WORDS fCont/nu» on reverse side If necessary and Identify by block number) Aqueous Film Forming Foam

Selective serotonin reuptake inhibitor discontinuation: side effects and other factors that influence medication adherence.

PubMed

Goethe, John W; Woolley, Stephen B; Cardoni, Alex A; Woznicki, Brenda A; Piez, Deborah A

2007-10-01

Patients with major depression discontinue taking their antidepressants for many reasons. Although side effects are often cited as the reason for discontinuation, few prospective studies have addressed this question, and none has specifically examined discontinuation in patients with severe depression. Inpatients and outpatients treated with a selective serotonin reuptake inhibitor for major depressive disorder were identified after admission. Three months later, patients were contacted and interviewed to determine antidepressant usage and the side effects experienced, including when these were experienced and their severity. Between October 2001 and April 2003, 406 English- or Spanish-speaking patients aged 18 to 75 years were followed up. One in 4 patients discontinued the index antidepressant. Among specific side effects noted, only "change in weight" and "anxiety" were significant predictors of discontinuation after controlling for confounders. Experiencing 1 or more "extremely" bothersome side effects was associated with more than a doubling of the risk of discontinuation, but the presence of side effects and side effects less severe than "extremely" bothersome were not significant predictors. There were no differences among selective serotonin reuptake inhibitor antidepressants in either the presence/absence of side effects or in the discontinuation rates. The results suggest that the contribution of side effects to antidepressant discontinuation is more complex than previously suggested. Disparate findings from earlier studies may reflect aspects of study design, such as examining populations whose severity of depression varied widely or not controlling for important confounding factors. Future research should separately examine high-risk groups (or control for severity of depression) and carefully rule out other potential contributors to discontinuation.

Side-by-side placement of bilateral endoscopic metal stents for the treatment of postoperative biliary stricture.

PubMed

Kaino, Seiji; Sen-Yo, Manabu; Shinoda, Shuhei; Kawano, Michitaka; Harima, Hirofumi; Suenaga, Shigeyuki; Sakaida, Isao

2017-02-01

Postoperative biliary strictures are usually complications of cholecystectomy. Endoscopic plastic stent prosthesis is generally undertaken for treating benign biliary strictures. Recently, fully covered metal stents have been shown to be effective for treating benign distal biliary strictures. We present the case of a 53-year-old woman with liver injury in which imaging studies showed a common hepatic duct stricture. Endoscopic retrograde cholangiopancreatography also confirmed the presence of a common hepatic duct stricture. Temporally fully covered metal stents with dilated diameters of 6 mm were placed in a side-by-side fashion in the left and right hepatic ducts, respectively. We removed the stents 2 months after their placement. Subsequent cholangiography revealed an improvement in the biliary strictures. Although we were apprehensive about the fully covered metal stents obstructing the biliary side branches, we noted that careful placement of the bilateral metal stents did not cause any complications. Side-by-side deployment of bilateral endoscopic fully covered metal stents can be one of the safe and effective therapies for postoperative biliary stricture.

Antipsychotics activate the TGFβ pathway effector SMAD3

PubMed Central

Cohen, T.; Sundaresh, S.; Levine, F.

2014-01-01

Although effective in treating an array of neurological disorders, antipsychotics are associated with deleterious metabolic side effects. Through high-throughput screening, we previously identified phenothiazine antipsychotics as modulators of the human insulin promoter. Here, we extended our initial finding to structurally diverse typical and atypical antipsychotics. We then identified the TGFβ pathway as being involved in the effect of antipsychotics on the insulin promoter, finding that antipsychotics activated SMAD3, a downstream effector of the TGFβ pathway, through a receptor distinct from the TGFβ receptor family and known neurotransmitter receptor targets of antipsychotics. Of note, antipsychotics that do not cause metabolic side effects did not activate SMAD3. In vivo relevance was demonstrated by reanalysis of gene expression data from human brains treated with antipsychotics, which showed altered expression of SMAD3 responsive genes. This work raises the possibility that antipsychotics could be designed that retain beneficial CNS activity while lacking deleterious metabolic side effects. PMID:22290122

3. View of side of house facing north from adjacent ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. View of side of house facing north from adjacent property. Original wood siding and trim is visible. Note: later addition to rear of house is shown in right side of photograph. - 322 South Fifteenth Street (House), Louisville, Jefferson County, KY

Pi'ilani Highway side on south side of island, Manawainui Bridge, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Pi'ilani Highway side on south side of island, Manawainui Bridge, constructed in 1993 to modern ASHTO standards; note difference in scale with historic Hana Belt Road bridges - Hana Belt Road, Between Haiku and Kaipahulu, Hana, Maui County, HI

General view looking aft along the port side of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

General view looking aft along the port side of the Orbiter Discovery into its payload bay. Note the Remote Manipulator System, Canadarm, in the foreground mounted on the port side longeron. The Remote Sensor Arm is mounted on the opposite, starboard, longeron. Also note the airlock and the protective covering over the docking mechanism. This image was taken in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Worldwide Survey of Nonmedical Drug Use and Alcohol Use among Military Personnel: 1980.

DTIC Science & Technology

1980-11-14

unlimited IS SUPPLEMENTARY NOTES Prepared with assistance of: Yukiko Carnies and Edward Farley 19. KEY WORDS (Continua on rovers* side It necea" and IdentIy...158 IV. ALCOHOL USE ................................. 161 Prevalence of Alcohol Use ..................... 161 Adverse Physiological Effects of...FURTHER RESEARCH REQUIRED ................... 276 Determine the Proportion of Servicemembers with Impaired Military Effectiveness ....... 276

22. GENERAL VIEW FROM SOUTHWEST: WEST END AND SOUTH SIDE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. GENERAL VIEW FROM SOUTHWEST: WEST END AND SOUTH SIDE OF HOUSE (NOTE PARAPETED GABLE); SMOKE HOUSE TO RIGHT (NOTE STEPPED GABLE); OLD SMOKE HOUSE (NOW DEMOLISHED) NEXT TO TREE IN FOREGROUND; OLD KITCHEN (NOW DEMOLISHED) NEXT TO FENCE Photocopy of ca. 1870 photograph Collection of Springer Homestead Archives, c/o Gerald Cunningham, Jessup, Maryland - Levi Springer House, Fan Hollow Road, Uniontown, Fayette County, PA

Assessment of Efficacy of the 595-nm Pulsed Dye Laser in the Treatment of Facial Port-Wine Stains in Indian Patients.

PubMed

Khandpur, Sujay; Sharma, Vinod K

2016-06-01

Pulsed dye lasers have revolutionized treatment of port-wine stains (PWS). The authors' previous study with a 585-nm/0.45-millisecond pulsed dye laser (PDL) showed 25% to 75% improvement in 60% of facial PWS. The authors analyzed data on facial PWS treated with a 595-nm tunable PDL in Indian patients. Response was assessed subjectively on a scale of -1 to 5 (Investigator Global Assessment) by comparing pretreatment and posttreatment photographs. Patients' perception of change in PWS was also noted on a visual analog scale from 0 to 10 (Patient Global Assessment). Side effects were recorded. A total of 74 flat and 24 hypertrophic PWS in skin Types IV and V with a median lesion size of 56 cm and 102 cm, respectively, and color ranging from pink to purple were treated. They underwent a mean of 7.3 and 8.5 sessions (range: 4-10 session), respectively. A mean lightening of 54% in flat and 40% in hypertrophic PWS was observed. After 10 treatments, 46.6% of flat PWS cases showed >75% lightening and an equal number had 25% to 75% improvement. A >75% improvement was observed in 12.5% of hypertrophic PWS with 75% of cases showing between 25% to 75% improvement. No significant side effects were noted. The 595-nm tunable PDL produced moderate response with no significant side effects.

1. VIEW OF DOWNSTREAM SIDE OF DIVERSION DAM ON THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. VIEW OF DOWNSTREAM SIDE OF DIVERSION DAM ON THE SNAKE RIVER, LOOKING NORTHEAST. NOTE HEADGATE STRUCTURE ON NORTH BANK, SPILLWAY ON LEFT SIDE OF DAM, AND SPLASH LOGS ON DOWNSTREAM SIDE OF DAM. - Snake River Ditch, Headgate on north bank of Snake River, Dillon, Summit County, CO

9. Perspective view showing west side and part of south ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. Perspective view showing west side and part of south side of Frank-Jensen Summer Home. Note stone in-filling at cabin's base. - Frank-Jensen Summer Home, 17423 North Lake Shore Drive, Telma, Chelan County, WA

[Local cyclosporin A therapy of nummuli after epidemic keratoconjunctivitis--case report].

PubMed

Reinhard, T; Sundmacher, R

1997-03-01

Steroid therapy for persistent or recurrent nummular adenoviral keratoconjunctivitis (AK) has little benefit because of the frequent recurrences, and mostly "offers" only serious steroid side effects. Since January 1995, we have treated different patients with nummuli after AK with topical Ciclosporin A (CSA) in an attempt to achieve at least the same symptomatic effect as with steroids, however, without side effects. Here, we report about our experiences in a very severe case with longterm treatment. The patient was sent to our clinic 4 months after AK with confluent nummuli and Descemet folds, more severe in the right than in the left eye. Best corrected visual acuity was 0.05 in the right and 0.5 in the left eye. Topical CSA 2% 4 times daily was first administered only in the right eye. When after 6 weeks a reduction of nummuli was noted in the right eye, the left eye, which had not improved, was started on the same regime. Therapy was tapered and finally stopped after 12 months in the right and 10 months in the left eye, when only minor changes were left in the corneae. A prompt recurrence of nummuli in both eyes within 4 weeks forced us to resume CSA therapy. At present, both corneae are clear with full vision, and this result is stable with 1 drop of CSA daily. No side effects of CSA therapy have been noted. The disappearance of nummuli with topical CSA and even more the reappearance of nummuli after cessation of CSA therapy show that topical CSA is about as effective as topical steroids in the symptomatic treatment of non-scarred nummuli after KE without the serious steroid side effects. Topical CSA treatment of nummuli after KE is, therefore, a very recommendable alternative for the potentially dangerous steroid therapy. Generally valid data on risk of recurrences, dosage and general effectiveness could only be learned from prospective studies with large numbers of AK patients, which, however, are not available outside epidemics.

Subsonic aerodynamic characteristics of interacting lifting surfaces with separated flow around sharp edges predicted by a vortex-lattice method

NASA Technical Reports Server (NTRS)

Lamar, J. E.; Gloss, B. B.

1975-01-01

Because the potential flow suction along the leading and side edges of a planform can be used to determine both leading- and side-edge vortex lift, the present investigation was undertaken to apply the vortex-lattice method to computing side-edge suction force for isolated or interacting planforms. Although there is a small effect of bound vortex sweep on the computation of the side-edge suction force, the results obtained for a number of different isolated planforms produced acceptable agreement with results obtained from a method employing continuous induced-velocity distributions. By using the method outlined, better agreement between theory and experiment was noted for a wing in the presence of a canard than was previously obtained.

Bilateral coordination and the motor basis of female preference for sexual signals in canary song

PubMed Central

Suthers, Roderick A.; Vallet, Eric; Kreutzer, Michel

2012-01-01

SUMMARY The preference of female songbirds for particular traits in the songs of courting males has received considerable attention, but the relationship of preferred traits to male quality is poorly understood. Female domestic canaries (Serinus canaria, Linnaeus) preferentially solicit copulation with males that sing special high repetition rate, wide-band, multi-note syllables, called ‘sexy’ or A-syllables. Syllables are separated by minibreaths but each note is produced by pulsatile expiration, allowing high repetition rates and long duration phrases. The wide bandwidth is achieved by including two notes produced sequentially on opposite sides of the syrinx, in which the left and right sides are specialized for low or high frequencies, respectively. The emphasis of low frequencies is facilitated by a positive relationship between syllable repetition rate and the bandwidth of the fundamental frequency of notes sung by the left syrinx, such that bandwidth increases with increasing syllable repetition rate. The temporal offset between notes prevents cheating by unilaterally singing a note on the left side with a low fundamental frequency and prominent higher harmonics. The syringeal and respiratory motor patterns by which sexy syllables are produced support the hypothesis that these syllables provide a sensitive vocal–auditory indicator of a male's performance limit for the rapid, precisely coordinated interhemispheric switching, which is essential for many sensory and motor processes involving specialized contributions from each cerebral hemisphere. PMID:22875764

A preliminary report on the effects of paclitaxel-impregnated stents on sheep nasal mucosa.

PubMed

Herrmann, Brian W; Citardi, Martin J; Vogler, George; Gardner, Laura; Smith, Greg; Javer, Amin R; Burt, Helen M; Jackson, John; Kuhn, Frederick A

2004-01-01

Traditional frontal sinus stents serve only as mechanical devices. It has been proposed that stents also may serve as drug-delivery systems for the topical application of drugs that minimize postoperative scarring. Paclitaxel (Taxol), which has recognized antiscarring effects, may be incorporated via a polymeric formulation into standard rubber stents. The impact of topically applied paclitaxel on the morphology of the nasal mucosa is unknown. An adult sheep model was used for this study. A modified rubber T-tube stent (incorporating paclitaxel at varying dosages) was secured to each side of the septum in four animals (eight sides). An unmodified T-tube was placed on each side of one animal, a T-tube with the drug carrier (but no paclitaxel) was placed on each side of the second animal, and T-tubes with varying paclitaxel were placed on each side of the final two animals. After 4 weeks, animals were killed and the nasal mucosa was harvested. The nasal mucosa was sectioned and stained with hematoxylin and eosin. A pathologist then assessed the nasal mucosa for vascular congestion, glandular atrophy, chronic inflammation, mucosal metaplasia, and mucosal ulceration. No consistent histopathological differences were noted in the specimens. All specimens showed varying degrees of vascular congestion, glandular atrophy, chronic inflammation, and mucosal metaplasia; the paclitaxel-impregnated stents were not consistently associated with more severe mucosal injury. Finally, mucosal ulceration was noted to be very rare in all specimens. This preliminary report describes the impact of paclitaxel-impregnated stents on sheep nasal mucosa, which tolerated these stents very well. Because paclitaxel minimizes scarring reactions at very low concentrations, paclitaxel-impregnated stents may prove useful in clinical situations in which frontal sinus stenting is deemed necessary. Additional investigations with animal models, as well as clinical trials, may be warranted.

ETR HEAT EXCHANGER BUILDING, TRA644. SOUTH SIDE. CAMERA FACING NORTH. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ETR HEAT EXCHANGER BUILDING, TRA-644. SOUTH SIDE. CAMERA FACING NORTH. NOTE POURED CONCRETE WALLS. ETR IS AT LEFT OF VIEW. NOTE DRIVEWAY INSET AT RIGHT FORMED BY DEMINERALIZER WING AT RIGHT. SOUTHEAST CORNER OF ETR, TRA-642, IN VIEW AT UPPER LEFT. INL NEGATIVE NO. HD46-36-1. Mike Crane, Photographer, 4/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

RAUWOLFIA SERPENTINA—Prolonged Use in Elderly Hypertensive Patients

PubMed Central

Lipsett, Mortimer B.; Levine, Albert H.; Goldman, Ralph

1954-01-01

In a group of older, arteriosclerotic hypertensive patients treated with an extract of Rauwolfia over a long period, a mild hypotensive effect was noted after weeks, or occasionally months, of therapy. No dramatic responses were seen, but the so-called “tranquilizing” effect was readily apparent and was appreciated by the patients. Side effects were usually relatively minor, were transient and rarely necessitated stopping the drug. PMID:13209377

METHODOLOGICAL NOTES: Rotation of the swing plane of Foucault's pendulum and Thomas spin precession: two sides of one coin

NASA Astrophysics Data System (ADS)

Krivoruchenko, Mikhail I.

2009-08-01

Using elementary geometric tools, we apply essentially the same methods to derive expressions for the rotation angle of the swing plane of Foucault's pendulum and the rotation angle of the spin of a relativistic particle moving in a circular orbit (the Thomas precession effect).

Treatment of Menorrhagia with Tranexamic Acid. A Double-blind Trial

PubMed Central

Callender, Shei La T.; Warner, G. T.; Cope, E.

1970-01-01

In a double-blind trial tranexamic acid (Cyclokapron) 1 g. four times a day for the first four days of menstruation, significantly decreased menstrual blood loss in women with menorrhagia for which no organic cause had been found. No difference in side-effects was noted between the active and placebo treatment. PMID:4919554

Sissy Boy Mothering: Male Child Mother Figures in Middle-Grade Fantasy Literature

ERIC Educational Resources Information Center

Bray, Danielle Bienvenue

2015-01-01

As Amanda Diekman and Sarah Murnen (2004) note, studies of "nonsexist" children's books tend to focus on girls performing stereotypically masculine behaviors without consideration of how boy characters perform gender (p. 381); however, this narrow focus on girl figures in the identification of nonsexist works has two side-effects:…

Comparative randomised controlled clinical trial of a herbal eye drop with artificial tear and placebo in computer vision syndrome.

PubMed

Biswas, N R; Nainiwal, S K; Das, G K; Langan, U; Dadeya, S C; Mongre, P K; Ravi, A K; Baidya, P

2003-03-01

A comparative randomised double masked multicentric clinical trial has been conducted to find out the efficacy and safety of a herbal eye drop preparation, itone eye drops with artificial tear and placebo in 120 patients with computer vision syndrome. Patients using computer for at least 2 hours continuosly per day having symptoms of irritation, foreign body sensation, watering, redness, headache, eyeache and signs of conjunctival congestion, mucous/debris, corneal filaments, corneal staining or lacrimal lake were included in this study. Every patient was instructed to put two drops of either herbal drugs or placebo or artificial tear in the eyes regularly four times for 6 weeks. Objective and subjective findings were recorded at bi-weekly intervals up to six weeks. Side-effects, if any, were also noted. In computer vision syndrome the herbal eye drop preparation was found significantly better than artificial tear (p < 0.01). No side-effects were noted by any of the drugs. Both subjective and objective improvements were observed in itone treated cases. So, itone can be considered as a useful drug in computer vision syndrome.

DebriSat Pre Preshot Laboratory Analyses

DTIC Science & Technology

2015-03-27

plate on up range side. MLI Down range Up range SBU Marking Witness Plates: Post Test (protected) 17 Surfaces of samples under Whipple plates are...s SBU Marking Witness Plates Post Test : Whipple Plates 59 Bottom Middle Top Up range is to the right – note sharp band of deposits on up range side...Marking Hold down plates: Post test 63 Up range Note larger deposit fragments on the down range plate. Similar larger deposits were observed on

Device for determining frost depth and density

NASA Technical Reports Server (NTRS)

Huneidi, F.

1983-01-01

A hand held device having a forward open window portion adapted to be pushed downwardly into the frost on a surface, and a rear container portion adapted to receive the frost removed from the window area are described. A graph on a side of the container enables an observer to determine the density of the frost from certain measurements noted. The depth of the frost is noted from calibrated lines on the sides of the open window portion.

Low-fluence Q-switched Nd: YAG 1064-nm laser and intense pulsed light for the treatment of melasma.

PubMed

Vachiramon, V; Sirithanabadeekul, P; Sahawatwong, S

2015-07-01

Low-fluence Q-switched Nd:YAG 1064 nm laser (LFQS) and intense pulsed light (IPL) have been shown to be effective in the treatment of melasma. LFQS can target deeper pigment, while IPL can target a wide range of cutaneous structures. However, there is limited information on efficacy and side-effects of the combined treatment. To compare the efficacy and safety of combined LFQS and IPL therapy with LFQS monotherapy in the treatment of melasma. Twenty female patients with mixed-type melasma on both cheeks were treated with LFQS on full face for five sessions at 1-week intervals. One side of the face was randomly assigned to receive additional three sessions of IPL treatments at 2-week intervals. Patients were evaluated 12 weeks after the last treatment. Outcome measures include the assessment by colorimeter and calculated as relative lightness index (R*LI), modified Melasma Area and Severity Index (mMASI), patient satisfaction and adverse effects. Eighteen patients completed the study. Both sides of the face showed significant improvement of R*LI and mMASI. A more rapid improvement of R*LI and mMASI was observed on combined side. At the end of treatment, 55% improvement and 37% improvement of R*LI was observed on combined side and monotherapy side respectively. The overall patients' satisfaction was in favour of the combined side. Recurrence occurred on both sides but there was still a significant decrease compared to baseline. No serious side effect was noted. The combination of LFQS and IPL results in faster clearance of melasma and is more effective than LFQS alone for melasma treatment. However, recurrence is still inevitable. © 2014 European Academy of Dermatology and Venereology.

17. VIEW OF INTERIOR, EAST SIDE, DECK LEVEL OF MST. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

17. VIEW OF INTERIOR, EAST SIDE, DECK LEVEL OF MST. NOTE CANVAS CURTAIN (RIGHT) USED TO COVER SOUTH SIDE OF MST BELOW LOWEST ENVIRONMENTAL DOORS. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

Field efficacy of moxidectin in dogs and rabbits naturally infested with Sarcoptes spp., Demodex spp. and Psoroptes spp. mites.

PubMed

Wagner, R; Wendlberger, U

2000-11-10

The efficacy of moxidectin 1% injectable for cattle was evaluated in dogs and rabbits with naturally acquired sarcoptic, demodectic or psoroptic mites. Twenty-two dogs with generalised demodicosis were orally treated with 0.4mg/kg moxidectin daily. Forty-one dogs suffering from sarcoptic mange were treated with 0.2-0.25mg/kg moxidectin either orally or subcutaneously every week for three to six times. Seven rabbits were treated orally with 0.2mg/kg moxidectin twice 10 days apart. Of the 22 dogs with demodicosis, 14% were stopped treatment because of side effects, 14% were lost and of the remaining 72% all were cured (mean therapy duration 2.4 months). Thirty-seven of the sarcoptic mange-infected dogs finished treatment and were cured. In 17% of dogs, side effects were noted. All seven rabbits treated for psoroptic mange were cured and did not show any side effect. Our results indicate that moxidectin is effective and a good alternative for the treatment of demodicosis and scabies in dogs and psoroptic mange in rabbits. Side effects seem to occur more frequently if applied subcutaneously, therefore the oral route should be preferred.

Propranolol in Treatment of Huge and Complicated Infantile Hemangiomas in Egyptian Children

PubMed Central

Hassan, Basheir A.; Shreef, Khalid S.

2014-01-01

Background. Infantile hemangiomas (IHs) are the most common benign tumours of infancy. Propranolol has recently been reported to be a highly effective treatment for IHs. This study aimed to evaluate the efficacy and side effects of propranolol for treatment of complicated cases of IHs. Patients and Methods. This prospective clinical study included 30 children with huge or complicated IHs; their ages ranged from 2 months to 1 year. They were treated by oral propranolol. Treatment outcomes were clinically evaluated. Results. Superficial cutaneous hemangiomas began to respond to propranolol therapy within one to two weeks after the onset of treatment. The mean treatment period that was needed for the occurrence of complete resolution was 9.4 months. Treatment with propranolol was well tolerated and had few side effects. No rebound growth of the tumors was noted when propranolol dosing stopped except in one case. Conclusion. Propranolol is a promising treatment for IHs without obvious side effects. However, further studies with longer follow-up periods are needed. PMID:24899888

Propranolol in treatment of huge and complicated infantile hemangiomas in egyptian children.

PubMed

Hassan, Basheir A; Shreef, Khalid S

2014-01-01

Background. Infantile hemangiomas (IHs) are the most common benign tumours of infancy. Propranolol has recently been reported to be a highly effective treatment for IHs. This study aimed to evaluate the efficacy and side effects of propranolol for treatment of complicated cases of IHs. Patients and Methods. This prospective clinical study included 30 children with huge or complicated IHs; their ages ranged from 2 months to 1 year. They were treated by oral propranolol. Treatment outcomes were clinically evaluated. Results. Superficial cutaneous hemangiomas began to respond to propranolol therapy within one to two weeks after the onset of treatment. The mean treatment period that was needed for the occurrence of complete resolution was 9.4 months. Treatment with propranolol was well tolerated and had few side effects. No rebound growth of the tumors was noted when propranolol dosing stopped except in one case. Conclusion. Propranolol is a promising treatment for IHs without obvious side effects. However, further studies with longer follow-up periods are needed.

Topical minoxidil in the treatment of alopecia areata.

PubMed Central

Fenton, D A; Wilkinson, J D

1983-01-01

A modified double blind crossover study was performed to assess the effect of 1% topical minoxidil as compared with placebo in 30 patients with alopecia areata and alopecia totalis. The active preparation produced a highly significant incidence of hair regrowth. A cosmetically acceptable response was noted in 16 patients. No side effects were seen. The study confirmed that topical minoxidil will induce new hair growth in alopecia areata but that it is less likely to do so in more severe and extensive disease. Furthermore, patients with alopecia universalis and totalis may not respond at all. Nevertheless, as compared with other drugs minoxidil applied topically is relatively non-toxic, is easy to use, and has no systemic or local side effects. Images p1016-a PMID:6412929

4. View of Clovelley Farm tenant house, back side (east) ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. View of Clovelley Farm tenant house, back side (east) area of two room addition. Note dark metal heating oil tank against rear wall and silver maple trees to shade house from south and east. - Clovelley Farm Tenant House, 4958 Paris Road (east side), Paris, Bourbon County, KY

Life-threatening complications of ibogaine: three case reports.

PubMed

Paling, F P; Andrews, L M; Valk, G D; Blom, H J

2012-11-01

Ibogaine is a naturally occurring psychoactive alkaloid extracted from the roots of the Tabernanthe iboga plant, which in alternative medicine is used to treat drug dependency. However, this upcoming, online advocated therapy can be dangerous due to its potentially lethal adverse effects. We present three cases in which toxic side effects were noted. We used the Naranjo scale to estimate the probability of a causal relationship between these effects and ibogaine. Findings in these three cases are suggestive of a causal relationship between the use of ibogaine and serious respiratory and cardiac problems (including lengthening of the QT interval). In our opinion it is of great importance that clinicians are aware of these potentially serious side effects and realise that widespread online marketing practices will give many more people access to ibogaine.

Closeup view from the starboard side looking towards the port ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Close-up view from the starboard side looking towards the port side of the Orbiter Discovery looking at the airlock and payload bay. The docking ring has been removed from the airlock prior to this photo being taken. Note that the Orbiter Boom Sensor System is still attached while the Remote Manipulator System has been removed. Also note the suspended protective panels and walkways in place to protect the interior surfaces of the payload bay doors while in their open position. This view was taken from a service platform in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

PERSPECTIVE VIEW FROM SOUTHWEST (STREET SIDE) OF 814 PARKWAY (APARTMENT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PERSPECTIVE VIEW FROM SOUTHWEST (STREET SIDE) OF 8-14 PARKWAY (APARTMENT BUILDINGS). NOTE ORIGINAL STEEL CASEMENT WINDOWS AND GLASS BLOCK. - Old Greenbelt, Crescent Road and Southway, Greenbelt, Prince George's County, MD

15. MIDPANEL POINT CONNECTION, NORTH SIDE BETWEEN THIRD AND FOURTH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. MID-PANEL POINT CONNECTION, NORTH SIDE BETWEEN THIRD AND FOURTH PANELS FROM WEST END OF TRUSS. NOTE NUMBERS STAMPED IN MEMBERS. - Riddle Bridge, Spanning Gasconada River, Dixon, Pulaski County, MO

European Science Notes Information Bulletin Reports on Current European/ Middle Eastern Science

DTIC Science & Technology

1988-07-01

41 Recently concluded and planned experiments are described which arc based on static Kerr effect dis- persion- spectroscopy , optical Kerr effect...studies, and both electric and magnetic resonance 6 molecular beam spectroscopy . These advanced techniques are used to measure with great precision...simuhItio , using thrcc-dimcn- flight using temperature-sensitive films and infrared sional singularities in a panel ncthod. camecras placed on either side

The Elimination of a Self-Injurious Avoidance Response through a Forced Running Consequence.

ERIC Educational Resources Information Center

Borreson, Paul M.

1980-01-01

The self-injurious avoidance responses of a 22-year-old severely mentally retarded male were eliminated through a forced running consequence. Side effects, such as reduced noise, increase in smiling, and faster progress toward instructional objectives, were also noted. The results were maintained over a period of two years. (Author/PHR)

Use of injectable hormonal contraceptives: diverging perspectives of women and men, service providers and policymakers in Uganda.

PubMed

Hyttel, Maria; Rasanathan, Jennifer J K; Tellier, Marianne; Taremwa, Willington

2012-12-01

The unmet need for family planning in Uganda is among the world's highest. Injectable contraceptives, the most available method, were used by only 14.1% of married women in 2011. Recent data suggest that the main reason for unmet need is not lack of access, but fear of and unacceptability of side effects. In this qualitative study, 46 women and men were interviewed about their experience of injectable contraceptive side effects and the consequences for their lives. Thirty-two family planning service providers and policymakers were also interviewed on their perceptions. While using injectables, many of the women experienced menstrual irregularities and loss of libido. Both women and men experienced strained sexual relationships and expressed fear of infertility, often resulting in contraceptive discontinuation. Family planning service providers and policymakers often minimized side effects as compared to the risks of unintended pregnancy. Policymakers noted a lack of contraceptive alternatives and promoted family planning education to correct what they thought were misconceptions about side effects among both service providers and contraceptive users. Information alone, however, cannot diminish disturbances to social and sexual relationships. A common understanding of recognised side effects, not only with injectables but all contraceptives, is necessary if unmet need in Uganda is to be reduced. Copyright © 2012 Reproductive Health Matters. Published by Elsevier Ltd. All rights reserved.

7. DETAIL CENTRAL PIER (SKEWBACK) WITH BREAKWATER, UPSTREAM (EAST) SIDE. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. DETAIL CENTRAL PIER (SKEWBACK) WITH BREAKWATER, UPSTREAM (EAST) SIDE. NOTE FRACTURES ALONG BARREL ARCH EXTRADOS. - Roaring Creek Bridge, State Road 2005 spanning Roaring Creek in Locust Township, Slabtown, Columbia County, PA

57. BUILDING NO. 1071, ORDNANCE FACILITY (CRYSTALLIZATION BUILDING), LOOKING AT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

57. BUILDING NO. 1071, ORDNANCE FACILITY (CRYSTALLIZATION BUILDING), LOOKING AT SOUTHEAST SIDE. NOTE ESCAPE CHUTES PROJECTING FROM SIDES OF BUILDING. - Picatinny Arsenal, State Route 15 near I-80, Dover, Morris County, NJ

PERSPECTIVE NORTHEAST. NOTE TYPICAL NEW HAMPSHIRE COVERED BRIDGE HOUSING, WITH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PERSPECTIVE NORTHEAST. NOTE TYPICAL NEW HAMPSHIRE COVERED BRIDGE HOUSING, WITH UPPER PORTION OF TRUSSES LEFT EXPOSED AND VERTICAL PLANK SIDING COVERING THE LOWER PORTION. - Mechanic Street Bridge, Spanning Israel River, Lancaster, Coos County, NH

16. Detail, northeast facade, operator's bow window and tower; note ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

16. Detail, northeast facade, operator's bow window and tower; note condition of slates on tower skirt roof, missing section of gutter at left side of skirt roof, missing window panes; note also knee braces carried on masonry ancons; view to southwest, 90mm lens. - Southern Pacific Depot, 559 El Camino Real, San Carlos, San Mateo County, CA

4. INTERIOR VIEW OF CHEMISTRY LAB LOOKING SOUTHEAST; NOTE FUME ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. INTERIOR VIEW OF CHEMISTRY LAB LOOKING SOUTHEAST; NOTE FUME EXHAUST HOOD AT LEFT & ORIGINAL CEILING FIXTURE - Fort McCoy, Building No. T-1033, North side of South Tenth Avenue, Block 10, Sparta, Monroe County, WI

European Science Notes. Volume 41, Number 8.

DTIC Science & Technology

1987-08-01

trations, as reported by B. Volesky 420 ESN 41-8 (1987) (Department of Chemical Engineering, biosorption metal concentration processes McGill...UniVersity, Montreal, Canada). can be effected on both sides of the Biosorption is a property of certdin process cycle--i.e., during the uptake types of...extractive process based ents have been isssued for the use of a on biosorption . In addition, the physical very effective common mold of genus properties

Acupuncture in the treatment of renal colic.

PubMed

Lee, Y H; Lee, W C; Chen, M T; Huang, J K; Chung, C; Chang, L S

1992-01-01

A prospective randomized study was performed to compare the effect of acupuncture and intramuscular Avafortan injection in the treatment of renal colic. Our results showed that acupuncture is as effective in relieving renal colic as Avafortan but it had a more rapid analgesic onset (3.14 +/- 2.88 minutes versus 15.44 +/- 7.55 minutes, p less than 0.05). Of the patients in the Avafortan group 7 (43.8%) had side effects, including skin rash in 3, tachycardia in 2, drowsiness in 1 and facial flush in 1. No side effects were noted in the acupuncture group. During 2 hours of observation acupuncture and Avafortan seemed to be ineffective in promoting stone passage. However, patients receiving Avafortan treatment were more likely to have paralytic ileus. In summary, acupuncture can be a good alternative for the treatment of renal colic.

Detail view looking aft along the starboard side of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view looking aft along the starboard side of the Orbiter Discovery where the forward section meets the mid-fuselage. Note the head of the jack stand and its mechanism to connect to the one of the forward hoist attach points of the orbiter. Also note the support structure of the service platforms. This view was taken from the service platform in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

The medical necessity for medicinal cannabis: prospective, observational study evaluating the treatment in cancer patients on supportive or palliative care.

PubMed

Bar-Sela, Gil; Vorobeichik, Marina; Drawsheh, Saher; Omer, Anat; Goldberg, Victoria; Muller, Ella

2013-01-01

Background. Cancer patients using cannabis report better influence from the plant extract than from synthetic products. However, almost all the research conducted to date has been performed with synthetic products. We followed patients with a medicinal cannabis license to evaluate the advantages and side effects of using cannabis by cancer patients. Methods. The study included two interviews based on questionnaires regarding symptoms and side effects, the first held on the day the license was issued and the second 6-8 weeks later. Cancer symptoms and cannabis side effects were documented on scales from 0 to 4 following the CTCAE. The distress thermometer was used also. Results. Of the 211 patients who had a first interview, only 131 had the second interview, 25 of whom stopped treatment after less than a week. All cancer or anticancer treatment-related symptoms showed significant improvement (P < 0.001). No significant side effects except for memory lessening in patients with prolonged cannabis use (P = 0.002) were noted. Conclusion. The positive effects of cannabis on various cancer-related symptoms are tempered by reliance on self-reporting for many of the variables. Although studies with a control group are missing, the improvement in symptoms should push the use of cannabis in palliative treatment of oncology patients.

Electroconvulsive therapy--efficacy and side-effects.

PubMed

Moksnes, Kjell Martin; Ilner, Stein Opjordsmoen

2010-12-16

Efficacy of electroconvulsive therapy (ECT) and duration of associated side effects is uncertain. We wanted to study indications, efficacy, time to response and side effects. ECT-protocols and medical records (from the period 1960-95) in three psychiatric wards of Dikemark Mental Hospital, Norway were systematically assessed. 141 persons underwent 241 ECT series comprising 1960 treatment sessions. Major depressive disorder was the main diagnosis in most patients 124 [88 %]. Before ECT, 129 (91 %) patients had been treated with at least one antidepressant, 107 (76 %) with at least two and 67 (48 %) with two different classes of antidepressants without sufficient clinical recovery from the incident. 31 (22 %) had received lithium before ECT. Within four weeks after the first ECT, 120 (85 %) patients had recovered. 61 of these achieved remission and were discharged within four weeks. After the first ECT series, 92 patients showed signs of improvement. 71 (77 %) had signs of improvement within 6 days. Side effects were noted after 123 of totally 241 series (51 %). Five patients experienced serious complications. Interpretation. The immediate effect of ECT was good and signs of recovery were observed in most patients during the first week. Depressed psychotic patients and the elderly seemed to respond best. Considering these patients' serious and long-lasting disorders ECT was fairly safe and well tolerated.

8. AFRD WAREHOUSE, EAST SIDE DETAIL SHOWS CONNECTION OF LEANTO ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. AFRD WAREHOUSE, EAST SIDE DETAIL SHOWS CONNECTION OF LEAN-TO TO WALL. FACING WEST. NOTE THE PROFILE OF THE METAL AWNING ON SOUTH SIDE. ELECTRICAL CONDUIT AND OTHER SERVICES PENETRATE WALL. POLE SECURED WITH TRIANGULAR BRACES AT CORNER IS COMMUNICATION POLE. - Minidoka Relocation Center Warehouse, 111 South Fir Street, Shoshone, Lincoln County, ID

19. MAIN MEETING ROOM LOOKING SOUTH FROM GALLERY. Note coved ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

19. MAIN MEETING ROOM LOOKING SOUTH FROM GALLERY. Note coved extension of gallery, erected when offices were built on gallery for the use of the Friends Service Committee in 1936. Note also the short stair balusters resulting from the wide modesty stair stringer provided for the women's side. - Twelfth Street Meeting House, 20 South Twelfth Street, Philadelphia, Philadelphia County, PA

Tardive Dyskinesia and Intellectual Disability: An Examination of Demographics and Topography in Adults with Dual Diagnosis and Atypical Antipsychotic Use

ERIC Educational Resources Information Center

Fodstad, Jill C.; Bamburg, Jay W.; Matson, Johnny L.; Mahan, Sara; Hess, Julie A.; Neal, Daniene; Holloway, Jodie

2010-01-01

Atypical antipsychotic medications are commonly used in large-scale residential care facilities for adults with developmental disabilities. While the benefits of this class of psychotropics are noted, debate exists whether the side effect profile of these medications outweigh their therapeutic benefit, especially in those who use them long-term.…

DETAIL OF BEEHIVE COKE OVEN DOOR, LOOKING NORTH; NOTE FIREBRICK ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL OF BEEHIVE COKE OVEN DOOR, LOOKING NORTH; NOTE FIRE-BRICK ARCH AND IRON JAMB AND SILL - Nuttallburg Mine Complex, Coke Ovens, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

East side, view of onehalf of the (open) carriage gate ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

East side, view of one-half of the (open) carriage gate (note: gate dates to CA. 1960, designed by Sam G. Stoney, fabricated by Philip Simons) - Morris-Gadsden House, 329 East Bay Street, Charleston, Charleston County, SC

Analysis of the arterial anatomical variations of thyroid gland: anatomic guide for surgical neck dissection.

PubMed

Ray, B; Pugazhandhi, B; D'Souza, A S; Saran, S; Fasil, M; Srinivasa, R S

2012-01-01

Aim of this study was to establish preliminary data on the variations of arterial supply of thyroid gland in Karnataka population. The anterior triangles in the neck of formalin fixed cadavers were dissected. The length, branching pattern, number and length of branches of superior thyroid artery (STA) were noted. We measured the length of inferior thyroid artery (ITA) from its point of emergence from thyrocervical trunk (TCT) to lower pole of thyroid gland. The length of the external carotid artery (ECA), TCT from the point of its emergence to the point of its branching was noted. We noted the number of branches from ITA and TCT. Presence of any additional artery supplying the thyroid gland was searched for. Difference in the length of STA and ITA between the two sexes and sides were noted. Statistical analysis was done by Student's t-test. In our study the maximum length of STA was 5.34cm and that of ITA was 5.07cm and there were no statistically significant side-to-side differences in level of bifurcation. Observations of the present study on the course and branching pattern of arteries around thyroid gland will help in easier approach during thyroid surgeries and interventional techniques (Tab. 1, Fig. 3, Ref. 38).

Effect of Sacroiliac Joint Manipulation on Selected Gait Parameters in Healthy Subjects.

PubMed

Wójtowicz, Sebastian; Sajko, Igor; Hadamus, Anna; Mosiołek, Anna; Białoszewski, Dariusz

2017-08-31

The sacroiliac joints have complicated biomechanics. While the movements in the joints are small, they exert a significant effect on gait. This study aimed to assess how sacroiliac joint manipulation influences selected gait parameters. The study enrolled 57 healthy subjects. The experimental group consisted of 26 participants diagnosed with dysfunction of one sacroiliac joint. The control group was composed of 31 persons. All subjects from the experimental group underwent sacroiliac joint manipulation. The experimental group showed significant lengthening of the step on both sides and the stride length in this group increased as well. Moreover, the duration of the stride increased (p=0.000826). The maximum midfoot pressure was higher and maximum heel pressure decreased. The differences were statistically significant. 1. Subclinical dysfunctions of the sacroiliac joints may cause functional gait disturbance. 2. Manipulation of the iliosacral joint exerts a significant effect on gait parameters, which may lead to improved gait economy and effec-tiveness. 3. Following manipulation of one iliosacral joint, altered gait parameters are noted on both the manipulated side and the contralateral side, which may translate into improved quality of locomotion.

Tolerance and safety of superficial chemical peeling with salicylic acid in various facial dermatoses.

PubMed

Bari, Arfan Ul; Iqbal, Zafar; Rahman, Simeen Ber

2005-01-01

Chemical peeling is a skin-wounding procedure that may have some potentially undesirable side-effects. The present study is directed towards safety concerns associated with superficial chemical peeling with salicylic acid in various facial dermatoses. The study was a non-comparative and a prospective one. Two hundred and sixty-eight patients of either sex, aged between 10 to 60 years, undergoing superficial chemical peeling for various facial dermatoses (melasma, acne vulgaris, freckles, post-inflammatory scars/pigmentation, actinic keratoses, plane facial warts, etc.) were included in the study. Eight weekly peeling sessions were carried out in each patient. Tolerance to the procedure and any undesirable effects noted during these sessions were recorded. Almost all the patients tolerated the procedure well. Mild discomfort, burning, irritation and erythema were quite common but the incidence of major side-effects was very low and these too, were easily manageable. There was no significant difference in the incidence of side-effects between facial dermatoses (melasma, acne and other pigmentary disorders). Chemical peeling with salicylic acid is a well tolerated and safe treatment modality in many superficial facial dermatoses.

Closeup view looking aft from the starboard side of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Close-up view looking aft from the starboard side of the Orbiter Discovery looking into the payload bay and the bulkhead of the aft fuselage. Note the vertical stabilizer protruding slightly from beyond the clear sheeting used to keep positive pressure in the mid-fuselage and payload bay area during servicing. Note that the Orbiter Boom Sensor System is still attached while the Remote Manipulator System has been removed. Also note the suspended protective panels and walkways in place to protect the interior surfaces of the payload bay doors while in their open position. This view was taken from a service platform in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

4. VIEW OF NORTH FACE OF MST. NOTE: ENVIRONMENTAL DOOR ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. VIEW OF NORTH FACE OF MST. NOTE: ENVIRONMENTAL DOOR ON THE LOWER EAST SIDE OF THE NORTH FACE IS MISSING. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

Sculpture, standing Lion, with scale (note: not in original location, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Sculpture, standing Lion, with scale (note: not in original location, now placed at the south side of Building No. 188) - National Park Seminary, Bounded by Capitol Beltway (I-495), Linden Lane, Woodstove Avenue, & Smith Drive, Silver Spring, Montgomery County, MD

7. Oblique view, east and north side, view to southwest. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Oblique view, east and north side, view to southwest. Note expansive use of glass to provide natural light to interior. - Interurban Electric Railway Bridge Yard Shop, Interstate 80 at Alameda County Postmile 2.0, Oakland, Alameda County, CA

A&M. Hot liquid waste treatment building (TAN616), south side. Camera ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

A&M. Hot liquid waste treatment building (TAN-616), south side. Camera facing north. Personnel door at left side of wall. Partial view of outdoor stairway to upper level platform. Note concrete construction. Photographer: Ron Paarmann. Date: September 22, 1997. INEEL negative no. HD-20-1-3 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

Cheap electricity from French tides

NASA Astrophysics Data System (ADS)

Andre, H.

1980-02-01

A tidal power plant built in Saint-Malo, France is examined, and some of the problems that have resulted in recent years are analyzed. These include mechanical problems due to turbine runner-blade seal failure and electrical problems involving electroerosion and structural station difficulties. the effects of tidal power plants on the environment are discussed, and it is noted that all possible side effects of the operations are very limited. Attention is given to the basic requirements for constructing power sites.

PBF (PER620) west facade. Camera facing east. Note 1980 addition ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PBF (PER-620) west facade. Camera facing east. Note 1980 addition on south side of west wall. Date: March 2004. INEEL negative no. HD-41-3-3 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

20. VIEW TO SOUTHWEST. DOLPHIN. (Photographed from boat) NOTE CUTWATER ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

20. VIEW TO SOUTHWEST. DOLPHIN. (Photographed from boat) NOTE CUTWATER ON UPSTREAM SIDE OF DOLPHIN, AND THAT DOLPHIN IS OCTAGONAL AS OPPOSED TO CIRCULAR DESIGN OF CENTER PIER. - Gianella Bridge, Spanning Sacramento River at State Highway 32, Hamilton City, Glenn County, CA

1. SOUTH (FRONT) AND WEST SIDE OF HOME OF JOHN ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. SOUTH (FRONT) AND WEST SIDE OF HOME OF JOHN A. MOORE, SECRETARY AND LATER PRESIDENT OF WARWOOD TOOL CO. (NOTE WARWOOD TOOL IN THE BACKGROUND, BETWEEN THE HOUSES) - Warwood Tool Company, Worker's House, 142 Eighteenth Street, Wheeling, Ohio County, WV

ETR BUILDING, TRA642. SOUTH SIDE VIEW INCLUDES SOUTH SIDES OF ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ETR BUILDING, TRA-642. SOUTH SIDE VIEW INCLUDES SOUTH SIDES OF ETR BUILDING (HIGH ROOF LINE); ELECTRICAL BUILDING (ONE-STORY, MADE OF PUMICE BLOCKS), TRA-648; AND HEAT EXCHANGER BUILDING (WITH BUILDING NUMBERS), TRA-644. NOTE PROJECTION OF ELECTRICAL BUILDING AT LEFT EDGE OF VIEW. CAMERA FACES NORTH. INL NEGATIVE NO. HD46-37-3. Mike Crane, Photographer, 4/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

A Modified Prophylactic Regimen for the Prevention of Otitis Externa in Saturation Divers

DTIC Science & Technology

2013-10-01

Prophylactic Regimen for the Prevention of Otitis Externa in Saturation Divers Authors: DISTRIBUTION STATEMENT A. Paul C. Algra, LT, MC...May 2012 – May 2013 4. TITLE AND SUBTITLE A Modified Prophylactic Regimen for the Prevention of Otitis Externa in Saturation Divers...SUPPLEMENTARY NOTES 14. ABSTRACT To prevent acute otitis externa (AOE) in the saturation setting and to decrease the side effects

Coal bunker, B123 off starboard side of boiler room B3. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Coal bunker, B-123 off starboard side of boiler room B-3. Compartment B-19 looking fore to aft into bunker C-101; note construction details of hull framing and protective deck at top of photograph. Bunkers loaded with coal surrounded the boiler room and afforded protection in addition to the coffer dam and armored protective deck. Note watertight door at lower center right. This could be lowered to cut off the bunker in the event of hull penetration. (053) - USS Olympia, Penn's Landing, 211 South Columbus Boulevard, Philadelphia, Philadelphia County, PA

Evaluation of changes to foot shape in females 5 years after mastectomy: a case-control study.

PubMed

Głowacka-Mrotek, Iwona; Sowa, Magdalena; Siedlecki, Zygmunt; Nowikiewicz, Tomasz; Hagner, Wojciech; Zegarski, Wojciech

2017-06-01

The aim of this study was to evaluate changes in foot shape of women 5 years after undergoing breast amputation. Evaluation of foot shape was performed using a non-invasive device for computer analysis of the plantar surface of the foot. Obtained results were compared between feet on the healthy breast side (F1) and on the amputated breast side (F2). 128 women aged 63.60 ± 8.83, 5-6 years after breast amputation were enrolled in this case-control study. Weight bearing on the lower extremity on the amputated breast side (F1) compared with the healthy breast side (F2) showed statistically significant differences (p < 0.01). Patients put more weight onto the healthy breast side. No statistically significant difference was found with regard to F1 and F2 foot length (p = 0.4239), as well as BETA (p = 0.4470) and GAMMA (p = 0.4566) angles. Highly statistically significant differences were noted with respect to foot width, ALPHA angle, and Sztriter-Godunov index-higher values were observed on the healthy breast side (p < 0.001). Highly statistically significant differences were also noted while comparing Clark's angles, higher values being observed on the operated breast side (p < 0.001). Differences in foot shape on the healthy breast side and amputated breast side constitute a long-term negative consequence of mastectomy, and can be caused by unbalanced weight put on feet on the healthy breast side compared to the amputated breast side.

SideRack: A Cost-Effective Addition to Commercial Zebrafish Housing Systems

PubMed Central

Burg, Leonard; Gill, Ryan; Balciuniene, Jorune

2014-01-01

Abstract Commercially available aquatic housing systems provide excellent and relatively trouble-free hardware for rearing and housing juvenile as well as adult zebrafish. However, the cost of such systems is quite high and potentially prohibitive for smaller educational and research institutions. The need for tank space prompted us to experiment with various additions to our existing Aquaneering system. We also noted that high water exchange rates typical in commercial systems are suboptimal for quick growth of juvenile fish. We devised a housing system we call “SideRack,” which contains 20 large tanks with air supply and slow water circulation. It enables cost-effective expansion of existing fish facility, with a key additional benefit of increased growth and maturation rates of juvenile fish. PMID:24611601

A case of generalized bromhidrosis following whole-body depilatory laser.

PubMed

Helou, Josiane; Haber, Roger; Kechichian, Elio; Tomb, Roland

2015-01-01

Laser treatment is a widespread method for hair removal. Despite its very common use, side effects remain relatively rare and transient. Axillary hyperhidrosis and bromhidrosis have already been reported in the literature after depilatory lasers. We report here a novel side effect of total body bromhidrosis following hair removal laser. A 27-year-old man, phototype 3 underwent four sessions of total body depilatory laser, combining pulsed alexandrite and pulsed diode lasers. A few days afterwards, a generalized foul odor was noted and was resistant to regular deodorants and Aluminum chloride based antiperspirants. Possible mechanisms include the activation of dormant bacteria in the skin flora, sweat gland dysfunction, altered skin flora, sweat gland hormone receptor disturbances, and genetic factors. Total body bromhidrosis and hyperhidrosis are potential complications of total body laser hair removal.

Elevation of southwest side with graduated pole, showing the tower ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Elevation of southwest side with graduated pole, showing the tower in the foreground, note the enclosed stairwell to the basement level on the right, view facing northeast - U.S. Naval Base, Pearl Harbor, Naval Radio Station, Operations Building, Wahiawa, Honolulu County, HI

55. TOP (4TH) FLOOR OF 187380 WING LOOKING NORTH, WEST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

55. TOP (4TH) FLOOR OF 1873-80 WING LOOKING NORTH, WEST SIDE. NOTE SECTION, LEFT SIDE, MIDDLEGROUND, WHERE SMALL HIGH WINDOWS INDICATE POINT AT WHICH 1852 WING JOINS THIS WING. - Boston Manufacturing Company, 144-190 Moody Street, Waltham, Middlesex County, MA

Laterality and Left-sidedness in the Nose, Face, and Body: A New Finding.

PubMed

Hafezi, Farhad; Javdani, Ali; Naghibzadeh, Bijan; Ashtiani, Abbas Kazemi

2017-12-01

Asymmetry is a common occurrence in bilaterian animals, particularly human beings. Through examination of patients and their photographs during rhinoplasty, we noted wider left-sided nasal and facial features in most patients. This observation led us to hypothesize that this might be consistent to the whole body. We conducted a study in 3 parts to test the question above. First, we analyzed operating notes of 50 rhinoplasty patients to determine the wider side of the upper, middle, and lower thirds of the nose. Second, we analyzed the width of the face and chest wall in 31 patients to discern any correlation between facial and bodily asymmetry. Third, computerized tomographic scans of the thorax and body of 48 patients were studied to measure the width of the hemithorax and hemipelvic bone. (1) Upper vault width was wider on left side (78%). Left middle vault width was wider (88%). The lower lateral cartilage, lateral crura convexity was more prominent on left side (48%), and a wider scroll area was found and trimmed in 21 (left) and 0 (right) cases. The alar base was wider on left side (56%). (2) In the body and face analysis, 64.5% had a wider left-sided face and body. (3) In the computed tomographic scan analysis, same-sided thorax and pelvis asymmetry was seen (85.35%), 33 and 7 of which were left- and right-sided, respectively. We observed generalized asymmetry of the face and body with left-sided predominance.

The Medical Necessity for Medicinal Cannabis: Prospective, Observational Study Evaluating the Treatment in Cancer Patients on Supportive or Palliative Care

PubMed Central

Bar-Sela, Gil; Vorobeichik, Marina; Drawsheh, Saher; Omer, Anat; Goldberg, Victoria; Muller, Ella

2013-01-01

Background. Cancer patients using cannabis report better influence from the plant extract than from synthetic products. However, almost all the research conducted to date has been performed with synthetic products. We followed patients with a medicinal cannabis license to evaluate the advantages and side effects of using cannabis by cancer patients. Methods. The study included two interviews based on questionnaires regarding symptoms and side effects, the first held on the day the license was issued and the second 6–8 weeks later. Cancer symptoms and cannabis side effects were documented on scales from 0 to 4 following the CTCAE. The distress thermometer was used also. Results. Of the 211 patients who had a first interview, only 131 had the second interview, 25 of whom stopped treatment after less than a week. All cancer or anticancer treatment-related symptoms showed significant improvement (P < 0.001). No significant side effects except for memory lessening in patients with prolonged cannabis use (P = 0.002) were noted. Conclusion. The positive effects of cannabis on various cancer-related symptoms are tempered by reliance on self-reporting for many of the variables. Although studies with a control group are missing, the improvement in symptoms should push the use of cannabis in palliative treatment of oncology patients. PMID:23956774

3. VIEW OF NORTHEAST CORNER OF MST. NOTE: ENVIRONMENTAL DOOR ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. VIEW OF NORTHEAST CORNER OF MST. NOTE: ENVIRONMENTAL DOOR ON THE LOWER EAST SIDE OF THE NORTH FACE IS MISSING. NORTH CAMERA TOWER IN FOREGROUND. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

VIEW LOOKING EAST AT 23 GREGG ST., A GOTHIC REVIVAL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW LOOKING EAST AT 23 GREGG ST., A GOTHIC REVIVAL HOUSE BUILT C. 1848 FOR FAMILIES OF MILL WORKERS, NOW WITH ADDITION ON SIDE. NOTE BOARD AND BATTEN VERTICAL SIDING AND DECORATIVE BARGE BOARDS IN FRONT GABLE - 23 Gregg Street (House), Graniteville, Aiken County, SC

101. CABLE DISTRIBUTION UNITS, SOUTHEAST SIDE OF LANDLINE INSTRUMENTATION ROOM ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

101. CABLE DISTRIBUTION UNITS, SOUTHEAST SIDE OF LANDLINE INSTRUMENTATION ROOM (106), LSB (BLDG. 770). NOTE CABLES ENTER CABLE DISTRIBUTION UNITS FROM OVERHEAD CABLE TRAYS. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

INTERIOR OF SOUTHEAST SIDE ENTRY CORRIDOR, SHOWING BLASTRESISTANT AND GASTIGHT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

INTERIOR OF SOUTHEAST SIDE ENTRY CORRIDOR, SHOWING BLAST-RESISTANT AND GAS-TIGHT DOOR. NOTE RELIEF VALVES NEAR BOTTOM OF DOOR AND ALTERED ONE IN BULKHEAD. - U.S. Naval Base, Pearl Harbor, Bombproof Personnel Shelter, Enterprise Street and St. Lo Avenue, Pearl City, Honolulu County, HI

Antiviral treatment of feline immunodeficiency virus-infected cats with (R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine.

PubMed

Taffin, Elien; Paepe, Dominique; Goris, Nesya; Auwerx, Joeri; Debille, Mariella; Neyts, Johan; Van de Maele, Isabel; Daminet, Sylvie

2015-02-01

Feline immunodeficiency virus (FIV), the causative agent of an acquired immunodeficiency syndrome in cats (feline AIDS), is a ubiquitous health threat to the domestic and feral cat population, also triggering disease in wild animals. No registered antiviral compounds are currently available to treat FIV-infected cats. Several human antiviral drugs have been used experimentally in cats, but not without the development of serious adverse effects. Here we report on the treatment of six naturally FIV-infected cats, suffering from moderate to severe disease, with the antiretroviral compound (R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine ([R]-PMPDAP), a close analogue of tenofovir, a widely prescribed anti-HIV drug in human medicine. An improvement in the average Karnofsky score (pretreatment 33.2 ± 9.4%, post-treatment 65±12.3%), some laboratory parameters (ie, serum amyloid A and gammaglobulins) and a decrease of FIV viral load in plasma were noted in most cats. The role of concurrent medication in ameliorating the Karnofsky score, as well as the possible development of haematological side effects, are discussed. Side effects, when noted, appeared mild and reversible upon cessation of treatment. Although strong conclusions cannot be drawn owing to the small number of patients and lack of a placebo-treated control group, the activity of (R)-PMPDAP, as observed here, warrants further investigation. © ISFM and AAFP 2014.

Flows about a rotating circular cylinder by the discrete-vortex method

NASA Astrophysics Data System (ADS)

Kimura, Takeyoshi; Tsutahara, Michihisa

1987-01-01

A numerical study has been conducted for flows past a rotating circular cylinder at high Reynolds numbers, using the discrete-vortex method. It is noted that the reverse Magnus effect is caused by the retreat of the separation point on the acceleration side. At high rotating speed, the nascent vortices of opposite directions are mixed faster, the wake becomes narrower, and predominating frequencies in the lift force disappear.

An Intervention to Control Vasomotor Symptoms for Advanced PC Patients on Hormone Therapy

DTIC Science & Technology

2014-08-01

Symptoms for Advanced PC Patients on Hormone Therapy PRINCIPAL INVESTIGATOR: Michael A. Diefenbach, Ph.D. CONTRACTING ORGANIZATION...Control Vasomotor Symptoms for Advanced PC Patients on Hormone Therapy 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-11-1-0604 5c...NOTES 14. ABSTRACT Vasomotor Symptom (Hot Flashes) is a common side-effect of hormone therapy for prostate cancer survivors who experience a rising

6. Oblique view of upstream side of Bridge Number 310.58, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Oblique view of upstream side of Bridge Number 310.58, 135mm lens. Note ashlar stone masonry abutment built in 1886, Tunnel 15 at left. Heavy vegetation cover, steep banks, and lack of streamside footing precluded full elevation views of the upstream and downstream sides of this bridge. - Southern Pacific Railroad Shasta Route, Bridge No. 310.58, Milepost 310.58, Sims, Shasta County, CA

22. INTERIOR VIEW OF TYPICAL OIL TANK, PORT SIDE, LOOKING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. INTERIOR VIEW OF TYPICAL OIL TANK, PORT SIDE, LOOKING FORWARD. NOTE SHIP'S FRAMING MEMBERS AND UNIVERSAL JOINT IN SHAFT FOR PUMPING VALVE AT BOTTOM OF TANK. THE ACCESS LADDER STEPS ARE MARKED WITH LEVEL INDICATIONS. - Ship "Falls of Clyde", Hawaii Maritime Center, Pier 7, Honolulu, Honolulu County, HI

How To Refinish Wood Siding With Latex Paints

Treesearch

E. A. Mraz

1976-01-01

Every homeowner with painted wood siding and trim at some time faces the job of repainting. In this note a simple test is described to determine whether an old surface will form a satisfactory bond with latex paints, and suggestions are given on preparing the surface to achieve a satisfactory bond.

1. VIEW OF EAST FRONT AND NORTH SIDE OF RADIO ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. VIEW OF EAST FRONT AND NORTH SIDE OF RADIO SHOP (BUILDING #2202) FACING SOUTHWEST. PHOTOGRAPH TAKEN FROM WITHIN BUILDING 2300; NOTE THE RECENT 'C.C.C.-STYLE' PORCH DETAIL, ADDED IN 1980s. - Medford Service Center, Radio Shop, 1319 McAndrews Road, Medford, Jackson County, OR

125. Pre1911. Crew on main deck, starboard side at main ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

125. Pre-1911. Crew on main deck, starboard side at main hatch, looking aft. Note dark object in center of photo that may be original main deck capstan. Fred Heick collection. (K9.9571) - Ship BALCLUTHA, 2905 Hyde Street Pier, San Francisco, San Francisco County, CA

10. VIEW TO NORTHEAST FROM WITHIN SOUTHWEST BAY, LOOKING THROUGH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. VIEW TO NORTHEAST FROM WITHIN SOUTHWEST BAY, LOOKING THROUGH CENTER BAY AND INTO NORTHEAST BAY. NOTE TRAVELING BRIDGE CRANE OVERHEAD AND SWINGING BOOM CRANES ATTACHED TO COLUMNS ON RIGHT AND LEFT. NOTE ALSO THE DIFFERENCE IN TRUSSES SUPPORTING CRANEWAY TRACKS FOR SIDE BAYS AND CENTER BAY. TRUSSES SUPPORTING CRANEWAY TRACKS IN SIDE BAYS (CENTER FOREGROUND AND FAR BACKGROUND) ARE HOWE TRUSSES WITH WOOD DIAGONALS AND STEEL VERTICALS. TRUSSES SUPPORTING CRANEWAY TRACKS IN CENTER BAY (MID BACKGROUND) ARE PRATT TRUSSES WITH WOOD VERTICALS AND DIAGONALS. - Rosie the Riveter National Historical Park, Auxiliary Plate Shop, 912 Harbour Way, Richmond, Contra Costa County, CA

General view looking aft from the starboard side of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

General view looking aft from the starboard side of the Orbiter Discovery looking into the payload bay and the bulkhead of the aft fuselage. Note that the Orbiter Boom Sensor System is still attached while the Remote Manipulator System has been removed. Also note the suspended protective panels and walkways in place to protect the interior surfaces of the payload bay doors while in their open position. This view was taken from a service platform in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Detail view of the starboard side of the aft fuselage ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view of the starboard side of the aft fuselage of the Orbiter Discovery in the Orbiter Processing Facility at Kennedy Space Center with the Orbiter Maneuvering/Reaction Control Systems Pod removed and exposing the insulating foil used to protect the orbiter structure from the heat generated by the maneuvering and reaction control engines. Also note in the view that the aft fuselage access door has bee removed and also note the ground support equipment attached to the T-0 umbilical plate in the lower left of the view. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bai,M.; Ptitsyn, V.; Roser, T.

To keep the spin tune in the spin depolarizing resonance free region is required for accelerating polarized protons to high energy. In RHIC, two snakes are located at the opposite side of each accelerator. They are configured to yield a spin tune of 1/2. Two pairs of spin rotators are located at either side of two detectors in each ring in RHIC to provide longitudinal polarization for the experiments. Since the spin rotation from vertical to longitudinal is localized between the two rotators, the spin rotators do not change the spin tune. However, due to the imperfection of the orbitsmore » around the snakes and rotators, the spin tune can be shifted. This note presents the impact of the horizontal orbital angle between the two snakes on the spin tune, as well as the effect of the vertical orbital angle between two rotators at either side of the collision point on the spin tune.« less

247. Axial Parkway alignment along ridge top. Note the open ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

247. Axial Parkway alignment along ridge top. Note the open vistas to either side of the roadway. These are maintained through vegetation management. The wood guide rail is a primary safety feature. View is to the northeast. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

GENERAL VIEW OF CHAPEL (smaller than church; to right of ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

GENERAL VIEW OF CHAPEL (smaller than church; to right of church). NOTE SERRATED PARAPET AND THE FAMOUS "ROSE WINDOW" IN CENTER. ALSO NOTE BUTTRESSES. SOUTH SIDE. Duplicate color view of HABS TX-333-B-1 - Mission San Jose y San Miguel de Aguayo, Chapel, 6539 San Jose Road, San Antonio, Bexar County, TX

Complementary approaches to decreasing discomfort during shockwave lithotripsy (SWL).

PubMed

Ngee-Ming, Goh; Tamsin, Drake; Rai, B P; Somani, B K

2014-06-01

Shock wave lithotripsy (SWL) is an established treatment for renal stones. Although non-invasive, it can cause significant pain and anxiety during the procedure. Our purpose was to review the literature to look at the effect of complimentary therapy in patients undergoing SWL and whether it led to a reduction in the requirement of analgesics and anxiolytics. A systematic review was performed on the use of acupuncture, auricular acupressure, transcutaneous electrical nerve stimulation (TENS) and music during SWL. Only prospective randomized controlled trials were selected. Two reviewers independently extracted the data from each study. Outcomes relating to analgesia requirement, anxiety and stone-free rates (SFR) were compared. Seven papers were identified reporting on 591 patients (acupuncture-3, TENS-1 and music-3). Pain control/analgesia requirement was significantly better in four studies (music-2, acupuncture-1, TENS-1). Significantly lower anxiety was noted in one study with music and two using acupuncture. No difference in SFR was noted with the use of complementary therapy. No major or minor side effects were noted. Complementary therapy for SWL can help lower analgesia requirement and the anxiety associated with it. However, it does not have any effect on the SFR.

123. Pre1911. View forward from near mizzen hatch, starboard side ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

123. Pre-1911. View forward from near mizzen hatch, starboard side showing crew standing on a load of lumber. Note main fife rail, small hatch with cover (possibly original 'lime juice hatch') just aft. Fred Heick Collection. - Ship BALCLUTHA, 2905 Hyde Street Pier, San Francisco, San Francisco County, CA

DETAIL OF THE SLOPING CONCRETE PAD AT THE SOUTH SIDE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL OF THE SLOPING CONCRETE PAD AT THE SOUTH SIDE OF THE GUN EMPLACEMENT. NOTE ADDED BLOCK OF CAST CONCRETE AT THE LOW (RIGHT) END OF SLOPED PAD. VIEW FACING SOUTHWEST - U.S. Naval Base, Pearl Harbor, Ford Island 5-Inch Antiaircraft Battery, East Gun Emplacement, Ford Island, Pearl City, Honolulu County, HI

124. Pre1911. View forward from mizzen shrouds, starboard side; Chinese ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

124. Pre-1911. View forward from mizzen shrouds, starboard side; Chinese cannery workers boarding ship from barge, S/V BENJAMIN F. PACKARD in background. Note main fife rail with fresh water pump. Fred Heick Collection. (G12.799) - Ship BALCLUTHA, 2905 Hyde Street Pier, San Francisco, San Francisco County, CA

5. VIEW OF FRONT (WEST AND SOUTH SIDES) TO NORTHEAST. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. VIEW OF FRONT (WEST AND SOUTH SIDES) TO NORTHEAST. VIEW TO NORTHEAST. NOTE THAT LARGE TREES PREVENT MORE COMPLETE VIEW FROM BETTER ANGLE. FOR MORE COMPLETE VIEW, SEE PHOTOGRAPHIC COPY OF 1916 PHOTO, NO. ID-17-C-35. - Boise Project, Boise Project Office, 214 Broadway, Boise, Ada County, ID

37. May 1985. LOOKING SOUTH DOWN HALL FROM PANTRY TO ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

37. May 1985. LOOKING SOUTH DOWN HALL FROM PANTRY TO SITTING ROOM (Door in foreground was exterior door in 1821 before addition of pantry; note wear in stone threshold) - Borough House, West Side State Route 261, about .1 mile south side of junction with old Garners Ferry Road, Stateburg, Sumter County, SC

Safety of the electroconvulsive therapy and amisulpride combination.

PubMed

Takács, Rozália; Iványi, Zsolt; Ungvari, Gabor S; Gazdag, Gábor

2013-03-01

Electroconvulsive therapy is frequently considered when pharmacotherapy is ineffective. In such cases the combination of the two treatment modalities are commonly used. Amisulpiride, a second generation antipsychotic drug is used in the treatment of schizophrenia and psychotic depression. When amisulpiride is ineffective as a monotherapy, combination with ECT could be an option to enhance its efficacy. To the best of our knowledge, to date there have been no data about the safety of this combination. Medical notes of all patients who were given ECT while on amisulpiride were selected from the archives of the Department of Psychiatry, Semmelweis University Medical School, Budapest, covering a 10-year period. A randomly selected matched control group was formed from patients who underwent ECT but were not taking amisulpiride. Patients in both groups also received a variety of psychotropic drugs other than amisulpide. Side effects were compared between the two groups of patients. Twenty patients received amisulpride with ECT. The most common side effects were headache, hypertension, tachycardia, nausea, dizziness, confusion, psychomotor agitation, sialorrhea, and prolonged seizure activity. All adverse effects resolved within 24 hours. No side effects of any kind were observed in 7 and 8 cases in the study and control groups, respectively. This was the first study that examined the safety of amisulpride-ECT combination in schizophrenia. Comparing the side-effects between the study and control groups, no significant differences were detected in terms of their types or frequency. The amisulpiride-ECT combination appears to be a safe treatment option.

Split-face comparison between single-band and dual-band pulsed light technology for treatment of photodamage.

PubMed

Varughese, Neal; Keller, Lauren; Goldberg, David J

2016-08-01

Intense pulsed light (IPL) has a well-recognized role in the treatment of photodamaged skin. To assess the safety and efficacy of a novel single-band IPL handpiece versus dual-band IPL handpiece in the treatment of photodamage. This was a prospective, single-center split-face study with 20 enrolled participants. Three treatments, 21 days apart, were administered to the subjects and follow-up was performed for 20 weeks. The left side of the face was treated with the single-band handpiece. The right side of the face was treated with the dual-band handpiece. Blinded investigators assessed the subjects' skin texture, pigmented components of photodamage, and presence of telangiectasia both before and after treatment, utilizing a five-point scale. Pigmented components of photodamage, skin texture, and presence of telangiectasias on the left and right side of the face were improved at the end of treatment. At 20-week follow-up, the side treated with single-band handpiece showed improvement in telangiectasia and pigmentation that was statistically superior to the contralateral side treated with the dual-band handpiece. Both devices equally improved textural changes. No adverse effects were noted with either device. Both single-band and dual-band IPL technology are safe and effective in the treatment of photodamaged facial skin. IPL treatment with a single-band handpiece yielded results comparable or superior to dual-band technology.

4. VIEW OF THE WEST FACADE. NOTE THE BRIDGES FROM ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. VIEW OF THE WEST FACADE. NOTE THE BRIDGES FROM THE D.L. & W. R.R. WOODWARD SIDING AND MAIN LINE IN THE LEFT FOREGROUND. PHOTO IS FROM THE LEVEE CROSSING TOBY CREEK FACING EAST. - Wyoming Valley Flood Control System, Woodward Pumping Station, East of Toby Creek crossing by Erie-Lackawanna Railroad, Edwardsville, Luzerne County, PA

Three day oral course of Augmentin to treat chancroid.

PubMed Central

Ndinya-Achola, J O; Nsanze, H; Karasira, P; Fransen, L; D'Costa, L J; Piot, P; Ronald, A R

1986-01-01

Amoxycillin and clavulanic acid (Augmentin; Beecham Research Laboratories) was used to treat patients with bacteriologically proved chancroid in three different dose regimens. A single dose of Augmentin (amoxycillin 3 g, clavulanic acid 350 mg) was found to be ineffective. A similar dose repeated after 24 hours was equally ineffective, but a dose (amoxycillin 500 mg, clavulanic acid 250 mg) given every 8 hours for three days was found to be effective. The drug was well tolerated and no side effects were noted in any of the patients treated. PMID:3733082

HOT CELL BUILDING, TRA632, INTERIOR. HOT CELL NO. 1 (THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HOT CELL BUILDING, TRA-632, INTERIOR. HOT CELL NO. 1 (THE FIRST BUILT) IN LABORATORY 101. CAMERA FACES SOUTHEAST. SHIELDED OPERATING WINDOWS ARE ON LEFT (NORTH) SIDE. OBSERVATION WINDOW IS AT LEFT OF VIEW (ON WEST SIDE). PLASTIC COVERS SHROUD MASTER/SLAVE MANIPULATORS AT WINDOWS IN LEFT OF VIEW. NOTE MINERAL OIL RESERVOIR ABOVE "CELL 1" SIGN, INDICATING LEVEL OF THE FLUID INSIDE THE THICK WINDOWS. HOT CELL HAS BEVELED CORNER BECAUSE A SQUARED CORNER WOULD HAVE SUPPLIED UNNECESSARY SHIELDING. NOTE PUMICE BLOCK WALL AT LEFT OF VIEW. INL NEGATIVE NO. HD46-28-1. Mike Crane, Photographer, 2/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

29. NORTH SIDE AND WEST REAR OF CAR BARN DURING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

29. NORTH SIDE AND WEST REAR OF CAR BARN DURING RECONSTRUCTION: Photocopy of May 1908 photograph showing the north side and west rear of powerhouse and car barn. The windows on the north wall of the building were later bricked up. Note the wooden roof trusses of the main building, and the different construction techniques used in rebuilding the 'annex,' closest to the viewer. - San Francisco Cable Railway, Washington & Mason Streets, San Francisco, San Francisco County, CA

SIDE-EFFECTS OF COMBINED RADIATION AND CHEMOTHERAPY IN THE TREATMENT OF MALIGNANT TUMORS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ottoman, R.E.; Langdon, E.A.; Rochlin, D.B.

1963-12-01

A study was made of the effects of 5-fluorouracil (FU) and x irradiation, separately and in combination, upon multiple metastatic tumors within individual patients. Fourteen cases satisfied the criteria for a controlled study. In 4, the effects of irradiation alone were greater than the combination, in 4 the effects were equal, and in 6 the effects of irradiation were less than those of combination therapy. This study failed to demonstrate a significant alteration in the tumor response by the addition of FU to x irradiation. Four instances of unusual reactions in previously irradiated skin were noted following FU administration. (auth)

[A patient with acute Philadelphia-chromosome-positive mixed phenotype leukemia developing ecthyma gangrenosum while undergoing combined imatinib mesylate chemotherapy].

PubMed

Suzuki, Kei; Sekine, Takao

2014-05-01

A 67-year-old woman with acute Philadelphia-chromosome-positive mixed phenotype leukemia developed bilateral periorbital ecthyma gangrenousum (EG) subsequent to periorbital edema while undergoing combined imatinib mesylate (imatinib) chemotherapy. Although initial periorbital edema was considered an imatinib side effect, the lesion deteriorated rapidly with high fever in the neutropenic phase, and the woman died of septic shock. Cultures from blood and exudative fluid grew Pseudomonas aeruginosa, after which EG was diagnosed. EG is a well-recognized emergent cutaneous infection most commonly associated with Pseudomonas aeruginosa bactremia. Because some patients present with EG a few days prior to developing life-threatening septicemia, it is important that EG be diagnosed correctly. Imatinib side effects such as edema are usually tolerable, and imatinib is widely used to treat Philadelphia-chromosome-positive leukemia, particularly in those with acute lymphoblastic leukemia, and neutropenic patients undergoing imatinib therapy are expected to increase in number. Delay in initiating appropriate therapy is correlated with poor outcome, so drug side effects and EG must be carefully differentiated when skin edema with surrounding erythema is noted in neutropenic patients undergoing imatinib therapy.

Double Mine Building (N) wall showing clerestory slot windows opening ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Double Mine Building (N) wall showing clerestory slot windows opening above level of main roof. Note structure is built on poured concrete foundation partly buried in hillside; view in southeast - Fort McKinley, Double Mine Building, East side of East Side Drive, approximately 125 feet south of Weymouth Way, Great Diamond Island, Portland, Cumberland County, ME

2. SOUTHEAST SIDE AND NORTHEAST REAR. SHOP BUILDING IN DISTANCE. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. SOUTHEAST SIDE AND NORTHEAST REAR. SHOP BUILDING IN DISTANCE. NOTE CONCRETE PROTECTION SLAB FOR UNDERGROUND CONTROL ROOM AND ESCAPE HATCH ON GROUND AT RIGHT MIDDLE DISTANCE. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Firing Control Building, Test Area 1-100, northeast end of Test Area 1-100 Road, Boron, Kern County, CA

10. Elevation view of south side of FrankJensen Summer Home. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. Elevation view of south side of Frank-Jensen Summer Home. Note that the steep angle of view gives an illusion of a flat roof. For a more accurate depiction of the roof line, see photos WA-207-4 and WA-207-8. - Frank-Jensen Summer Home, 17423 North Lake Shore Drive, Telma, Chelan County, WA

28. Photocopied August 1978. UPPER INTAKE COFFER DAM, OCTOBER 7, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

28. Photocopied August 1978. UPPER INTAKE COFFER DAM, OCTOBER 7, 1901. LOGS WERE PLACED ON THE WATER SIDE OF THIS DAM TO COUNTERACT WAVE ACTION AGAINST THE DAM. NOTE THE TIMBER RETAINING WALL ON THE NORTH SIDE OF THE LOWER INTAKE. (185) - Michigan Lake Superior Power Company, Portage Street, Sault Ste. Marie, Chippewa County, MI

1. VIEW OF EAST SIDE AND NORTH REAR OF GASANDOIL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. VIEW OF EAST SIDE AND NORTH REAR OF GAS-AND-OIL HOUSE (BUILDING #2500), FACING SOUTHWEST. (NOTE: CANOPY STRUCTURE NEXT TO BUILDING FORMERLY COVERED GAS PUMPS; CANOPY BUILT IN 1930s BUT MOVED TO THIS LOCATION IN ABOUT 1970.) - Medford Service Center, Gas & Oil House, 1319 McAndrews Road, Medford, Jackson County, OR

When "good" is not always right: effect of the consequences of motor action on valence-space associations.

PubMed

Brouillet, Denis; Milhau, Audrey; Brouillet, Thibaut

2015-01-01

Since the work of Casasanto (2009), it is now well established that valence and laterality are associated. Participants tend to prefer objects presented on their dominant side over items presented on their non-dominant side, and to place good items on their dominant side and bad items on the other side. Several studies highlight that those associations of valence and laterality are accounted for by the greater motor fluency of the dominant hand and various studies noted that these associations could be reversed depending on the way people interact with their environment. Consistently with the Theory of Event Coding, the aim of this work is to show that the consequences of motor actions could also reverse the associations between valence and laterality. Thus, if participants had to place two animals (one good, one bad) on two supports, one stable (no risk of falling), one unstable (risk of falling), we hypothesized that the good item would be placed on the stable support, regardless of the side where it would be put (i.e., on the dominant or non-dominant side). We expected the opposite for the bad item. The results of two experiments are consistent with this prediction and support the claim that the consequences of motor action bias the hedonic connotation of our dominant side.

When “good” is not always right: effect of the consequences of motor action on valence-space associations

PubMed Central

Brouillet, Denis; Milhau, Audrey; Brouillet, Thibaut

2015-01-01

Since the work of Casasanto (2009), it is now well established that valence and laterality are associated. Participants tend to prefer objects presented on their dominant side over items presented on their non-dominant side, and to place good items on their dominant side and bad items on the other side. Several studies highlight that those associations of valence and laterality are accounted for by the greater motor fluency of the dominant hand and various studies noted that these associations could be reversed depending on the way people interact with their environment. Consistently with the Theory of Event Coding, the aim of this work is to show that the consequences of motor actions could also reverse the associations between valence and laterality. Thus, if participants had to place two animals (one good, one bad) on two supports, one stable (no risk of falling), one unstable (risk of falling), we hypothesized that the good item would be placed on the stable support, regardless of the side where it would be put (i.e., on the dominant or non-dominant side). We expected the opposite for the bad item. The results of two experiments are consistent with this prediction and support the claim that the consequences of motor action bias the hedonic connotation of our dominant side. PMID:25798122

Topical effectiveness of kiwifruit versus fibrinolysin ointment on removal of necrotic tissue of full-thickness burns in male rats.

PubMed

Kooshiar, Hadi; Abbaspour, Hadi; Motamed Al Shariati, Seyed Mohamad; Rakhshandeh, Hasan; Khajavi Rad, Abolfazl; Esmaily, Habibollah; Vahdati Nia, Behnam

2012-01-01

Formation of necrotic tissues is a major issue affecting treatment of full-thickness burns. This study was designed to compare topical effectiveness of applying kiwifruit versus fibrinolysin on removal of necrotic tissue of burns. Ten adult male Wistar rats were randomly assigned to three groups. For group 1, the right-side wounds were treated with kiwifruit and the other side with fibrinolysin. For group 2, the wounds on the right side were treated with kiwifruit or fibrinolysin, and the left sides were kept as control group 2. All wounds in group 3 were considered as control group 1. The control wounds were left to heal naturally. In each group and for each wound, the time of debridement were noted. The results indicated that for the wounds where kiwifruit was applied, the average time for removal of dead tissue was 5.7 days, which is significantly shorter than the average 18.5 days it took for treatment with fibrinolysin (p = 0.02). However, there were no significant differences between control wounds 1 and 2. Findings of the present study can open new horizons and provide a new treatment modality for patients with deep burns. © 2012 Wiley Periodicals, Inc.

Experimental Studies on Pressure and Temperature Effects on Deep Dea Organisms.

DTIC Science & Technology

1980-02-28

SUPPLEMENTARY NOTES Research published in two papers: (a) George, R.Y. 1979. What Adaptive Strategies Promote Immig ration and Speciation in Deep Sea...Environment. Sarsia 64(1-2):61-65. (b) George, R.Y. 1979. Behavorial and 4etabolic Adaptations o Polar and Deep Sea Crustaceans. Bull. Biol. Soc. W ch #3...pages 283-296. 19. KE WORDS (Continue on reverse side If noeemy and Identify by block nuimber) Pressure adaptation , temperature-pressure interaction

78 FR 15783 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-12

..., L, O, Q, R, S, T, U, X, Z, 2, 7, CL, RQ, RR, RT, RX, and SW. The Exchange notes that this proposal..., O, Q, R, S, T, U, X, Z, 2, 7, CL, RQ, RR, RT, RX, and SW for securities priced below $1.00 that... dividing that result by two (2) to account for each side of the transaction: (0.30% x 1 share x $0.99...

JPRS Report, Soviet Union, Foreign Military Review, No. 2, February 1987

DTIC Science & Technology

1987-09-15

Losses to the U. S. population may reach 35 million people. The authors note that in the event that U. S. strategic nuclear forces are used...reserves created to carry out offensive operation (Khyber) (begun at the end of February 1984«), and suffering substantial losses (approximately 20,000...The two sides restored the combat effectiveness of their large units and units, which had suffered heavy losses , and prepared for new battles. The

Cutaneous side-effects in patients on long-term treatment with epidermal growth factor receptor inhibitors.

PubMed

Osio, A; Mateus, C; Soria, J-C; Massard, C; Malka, D; Boige, V; Besse, B; Robert, C

2009-09-01

Acute and subacute cutaneous side-effects of epidermal growth factor receptor inhibitors (EGFRIs) are very frequent and well known. Much less is known about the chronic cutaneous effects of these drugs and about their potential psychosocial impact on patients. We performed a retrospective study of patients treated with EGFRIs for more than 6 months. All patients had a detailed dermatological examination. The primary cancer, associated chemotherapies, skin treatment, evolution of skin symptoms and their impact on quality of life (QoL) as evaluated by the Dermatology Life Quality Index (DLQI) were noted. Seven men and nine women were identified. The mean length of EGFRI treatment was 10 months (range 6-27). At the time of examination, all patients (100%) had cutaneous side-effects. Grade I or II folliculitis was found in 37.5% of the patients. Additional skin manifestations were xerosis (100%), mucositis (69%), hair abnormalities (87.5%), eyelash trichomegaly (62.5%), facial hypertrichosis (56%), painful paronychia (56%) and onycholysis (44%). Dose reduction or EGFRI discontinuation for skin toxicity were needed in six patients (37.5%). DLQI evaluation showed a moderate to strong impact on QoL in four patients (25%). Cutaneous side-effects are found in 100% of patients treated with EGFRIs for more than 6 months and have a significant effect on patients' QoL. The clinical spectrum of skin manifestation varies over time. As the use of EGFRIs rapidly increases, it is critical for us to improve our knowledge in the understanding and managment of these skin manifestations.

STS-47 Commander Gibson and Pilot Brown at CCT side hatch during JSC training

NASA Technical Reports Server (NTRS)

1992-01-01

STS-47 Endeavour, Orbiter Vehicle (OV) 105, Spacelab Japan (SLJ) Commander Robert L. Gibson (right) and Pilot Curtis L. Brown, Jr, wearing launch and entry suits (LESs), pose in front of the Crew Compartment Trainer (CCT) mockup side hatch during post landing emergency egress procedures held at JSC's Mockup and Integration Laboratory (MAIL) Bldg 9NE. Note that the crew escape system (CES) pole is in position at side hatch but is not extended.

26. EAST FRONT AND SOUTH SIDE OF F&CH RWY POWERHOUSE: ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

26. EAST FRONT AND SOUTH SIDE OF F&CH RWY POWERHOUSE: Photocopy of a recently discovered c. 1904 photograph showing south side and east front of powerhouse and car barn. View is looking north along Mason Street. Cars exited the building and passed onto the mainline through the large doorway just to the right of the smokestack. Note the cable car descending Washington Street past the building. - San Francisco Cable Railway, Washington & Mason Streets, San Francisco, San Francisco County, CA

6. Elevation view of east side of southernmost end of ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Elevation view of east side of southernmost end of building. When joined with photo WA-116-A-7, these photos give a virtually complete elevation view of the east side of the 1896 south section of Building 59. Note that the steep angle of view gives the illusion of a flat roof. For a more accurate depiction of the roof slope, see previous photo's including WA-116-5. - Puget Sound Naval Shipyard, Pattern Shop, Farragut Avenue, Bremerton, Kitsap County, WA

34. TOP O THE BOILER SHOWING CONSTRUCTION DETAILS. NOTE THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

34. TOP O THE BOILER SHOWING CONSTRUCTION DETAILS. NOTE THE 1/2-INCH ROUND IRON REINFORCING ROD AND GALVANIZED FARM FENCING IN THE RIGHT FOREGROUND. AND THE EXPANDED METAL LATH WITH CEMENT COATING IN THE CEILING ABOVE THE BOILER. - Moravian Pottery & Tile Works, Southwest side of State Route 313 (Swamp Road), Northwest of East Court Street, Doylestown, Bucks County, PA

10. View south at base of smokestack. Note monitor roof ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. View south at base of smokestack. Note monitor roof and laboratory on filtration bed at rear of photograph. (Across Armory Street). Cylindrical object at lower center is a muffler for the turbine powered stand-by generator unit. - Lake Whitney Water Filtration Plant, Armory Street Pumphouse, North side of Armory Street between Edgehill Road & Whitney Avenue, Hamden, New Haven County, CT

Fluid-loading solutions and plasma volume: Astro-ade and salt tablets with water

NASA Technical Reports Server (NTRS)

Fortney, Suzanne M.; Seinmann, Laura; Young, Joan A.; Hoskin, Cherylynn N.; Barrows, Linda H.

1994-01-01

Fluid loading with salt and water is a countermeasure used after space flight to restore body fluids. However, gastrointestinal side effects have been frequently reported in persons taking similar quantities of salt and water in ground-based studies. The effectiveness of the Shuttle fluid-loading countermeasure (8 gms salt, 0.97 liters of water) was compared to Astro-ade (an isotonic electrolyte solution), to maintain plasma volume (PV) during 4.5 hrs of resting fluid restriction. Three groups of healthy men (n=6) were studied: a Control Group (no drinking), an Astro-ade Group, and a Salt Tablet Group. Changes in PV after drinking were calculated from hematocrit and hemoglobin values. Both the Salt Tablet and Astro-ade Groups maintained PV at 2-3 hours after ingestion compared to the Control Group, which had a 6 percent decline. Side effects (thirst, stomach cramping, and diarrhea) were noted in at least one subject in both the Astro-ade and Salt Tablet Groups. Nausea and vomiting were reported in one subject in the Salt Tablet Group. It was concluded that Astro-ade may be offered as an alternate fluid-loading countermeasure but further work is needed to develop a solution that is more palatable and has fewer side effects.

Adverse effects associated with ethanol catheter lock solutions: a systematic review.

PubMed

Mermel, Leonard A; Alang, Neha

2014-10-01

Antimicrobial lock therapy has been widely utilized internationally for the prevention and management of intravascular catheter-related bloodstream infections. One of the agents commonly utilized for lock therapy is ethanol. However, a systematic review of adverse events associated with ethanol locks has not been published. PubMed was searched to collect articles published from May 2003 through March 2014. The bibliographies of relevant articles were also reviewed. In vitro studies of the mechanical properties of catheters after ethanol immersion have revealed changes predominantly in polyurethane catheters and to a lesser extent in silicone and Carbothane catheters. An elution of polymers from polyurethane and Carbothane catheters has been observed at the ethanol concentrations used in ethanol lock therapy. Ethanol above a concentration of 28% leads to plasma protein precipitation. Ethanol locks were associated with catheter occlusion in 11 studies and independently increased the risk of thrombosis compared with heparin lock in a randomized trial. Six studies noted abnormalities in catheter integrity, including one case leading to catheter embolization. Of note, five of these studies involved silicone catheters. Ethanol lock use was associated with systemic side effects in 10 studies and possible side effects in one additional study. Four studies noted liver function test abnormalities, predominantly transaminase elevation, related to ethanol lock use. However, a prospective study did not find any difference in the risk of doubling the transaminase level above the normal range during use of ethanol locks compared with not using an ethanol lock. The use of ethanol locks has been associated with structural changes in catheters, as well as the elution of molecules from the catheter polymers. Clinical studies have revealed systemic toxicity, increased catheter occlusion and breaches in catheter integrity. © The Author 2014. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Aripiprazole augmentation in highly treatment-resistant obsessive-compulsive disorder - experience from a specialty clinic in India.

PubMed

Hegde, Aditya; Kalyani, Bangalore G; Arumugham, Shyam Sundar; Narayanaswamy, Janardhanan C; Math, Suresh Bada; Reddy, Y C Janardhan

2017-03-01

To study the effectiveness and tolerability of aripiprazole augmentation in patients with highly treatment-resistant obsessive-compulsive disorder (OCD) in a real-world scenario. We conducted a chart review of patients who were initiated on aripiprazole augmentation at a specialty OCD clinic in India between 2004 and 2014. Primary outcome measure was all-cause discontinuation. 23 patients were eligible for analysis. Patients had not achieved symptom remission despite a mean of over 3 prior SRI trials. Aripiprazole was continued to be used in seven patients (30%) at the time of last follow-up. Thirteen patients (57%) discontinued the drug due to side effects, and three patients (13%) discontinued aripiprazole citing no improvement. Six patients (26%) were noted to have ≥25% reduction on the Yale-Brown Obsessive-Compulsive Scale. The study demonstrated, in a real-world setting, that aripiprazole may be a useful augmenting agent in a proportion of patients with highly treatment-resistant OCD. However, side effects may lead to premature discontinuation in many of them.

A Comet Engulfs Mars: MAVEN Observations of Comet Siding Spring's Influence on the Martian Magnetosphere

NASA Technical Reports Server (NTRS)

Espley, Jared R.; Dibraccio, Gina A.; Connerney, John E. P.; Brain, David; Gruesbeck, Jacob; Soobiah, Yasir; Halekas, Jasper S.; Combi, Michael; Luhmann, Janet; Ma, Yingjuan

2015-01-01

The nucleus of comet C/2013 A1 (Siding Spring) passed within 141,000?km of Mars on 19 October 2014. Thus, the cometary coma and the plasma it produces washed over Mars for several hours producing significant effects in the Martian magnetosphere and upper atmosphere. We present observations from Mars Atmosphere and Volatile EvolutioN's (MAVEN's) particles and field's instruments that show the Martian magnetosphere was severely distorted during the comet's passage. We note four specific major effects: (1) a variable induced magnetospheric boundary, (2) a strong rotation of the magnetic field as the comet approached, (3) severely distorted and disordered ionospheric magnetic fields during the comet's closest approach, and (4) unusually strong magnetosheath turbulence lasting hours after the comet left. We argue that the comet produced effects comparable to that of a large solar storm (in terms of incident energy) and that our results are therefore important for future studies of atmospheric escape, MAVEN's primary science objective.

General view looking forward from the starboard side of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

General view looking forward from the starboard side of the Orbiter Discovery looking into the payload bay and the bulkhead of the forward fuselage with the airlock. The docking ring and airlock hatches have been removed from the airlock prior to this photo being taken. Note that the Orbiter Boom Sensor System is still attached while the Remote Manipulator System has been removed. Also note the suspended protective panels and walkways in place to protect the interior surfaces of the payload bay doors while in their open position. This view was taken from a service platform in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Absolute pitch among students at the Shanghai Conservatory of Music: a large-scale direct-test study.

PubMed

Deutsch, Diana; Li, Xiaonuo; Shen, Jing

2013-11-01

This paper reports a large-scale direct-test study of absolute pitch (AP) in students at the Shanghai Conservatory of Music. Overall note-naming scores were very high, with high scores correlating positively with early onset of musical training. Students who had begun training at age ≤5 yr scored 83% correct not allowing for semitone errors and 90% correct allowing for semitone errors. Performance levels were higher for white key pitches than for black key pitches. This effect was greater for orchestral performers than for pianists, indicating that it cannot be attributed to early training on the piano. Rather, accuracy in identifying notes of different names (C, C#, D, etc.) correlated with their frequency of occurrence in a large sample of music taken from the Western tonal repertoire. There was also an effect of pitch range, so that performance on tones in the two-octave range beginning on Middle C was higher than on tones in the octave below Middle C. In addition, semitone errors tended to be on the sharp side. The evidence also ran counter to the hypothesis, previously advanced by others, that the note A plays a special role in pitch identification judgments.

Diametric Quadrilaterals with Two Equal Sides

ERIC Educational Resources Information Center

Beauregard, Raymond A.

2009-01-01

If you take a circle with a horizontal diameter and mark off any two points on the circumference above the diameter, then these two points together with the end points of the diameter form the vertices of a cyclic quadrilateral with the diameter as one of the sides. We refer to the quadrilaterals in question as diametric. In this note we consider…

6. View of HiattStricklin House showing north gable back and ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. View of Hiatt-Stricklin House showing north gable back and east side. Note the porches, shsutters and chimney. The shiny squares on the siding are metal pieces to repair woodpecker holes, facing southwest. - Hiatt Property, House, West bank of Woof Creek, 400 feet northwest of intersection of U.S.F.S. Roads 651 & 349, Placerville, Boise County, ID

View of the forward section, port side, of the Orbiter ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View of the forward section, port side, of the Orbiter Discovery at ground level in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the exposed panels for systems access during ground support and vehicle turn-around processes. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Elevation (typical EBT Coal Hopper Car) with scale. 3 Bay ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Elevation (typical EBT Coal Hopper Car) with scale. 3 Bay Steel Hopper Car with side extensions raising coal carrying capacity to 80,000 pounds. Note cars on either side lack extensions limiting their coal capacity to 70,000 pounds - East Broad Top Railroad & Coal Company, State Route 994, West of U.S. Route 522, Rockhill Furnace, Huntingdon County, PA

ETR HEAT EXCHANGER BUILDING, TRA644. EAST SIDE. CAMERA FACING WEST. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ETR HEAT EXCHANGER BUILDING, TRA-644. EAST SIDE. CAMERA FACING WEST. NOTE COURSE OF PIPE FROM GROUND AND FOLLOWING ROOF OF BUILDING. MTR BUILDING IN BACKGROUND AT RIGHT EDGE OF VIEW. INL NEGATIVE NO. HD46-36-3. Mike Crane, Photographer, 4/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

PBF Reactor Building (PER620). Camera facing north toward south facade. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PBF Reactor Building (PER-620). Camera facing north toward south facade. Note west-wing siding on concrete block; high-bay siding of metal. Excavation and forms for signal and cable trenches proceed from building. Photographer: Kirsh. Date August 20, 1968. INEEL negative no. 68-3332 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

1. GENERAL VIEW OF EAST AND NORTH SIDES OF NORTH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. GENERAL VIEW OF EAST AND NORTH SIDES OF NORTH WING; NOTE PLYWOOD COVERED WINDOWS DUE TO EXPLOSION ON LAUNCH PAD A IN MARCH 1997 WITH FIERY RAIN OF SOLID ROCKET FUEL AND PROLONGED CONCUSSION WAVES; VIEW TO SOUTHWEST. - Cape Canaveral Air Station, Launch Complex 17, Facility 36001, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

Institutional Denial about the Dark Side of Law School, and Fresh Empirical Guidance for Constructively Breaking the Silence.

ERIC Educational Resources Information Center

Krieger, Lawrence S.

2002-01-01

Noting evidence of the "dark side" of legal education and the process of denial among faculty, describes recent psychological research on the components of happiness and life satisfaction. Asserts that this research provides an objective framework for understanding the pervasive problems in legal education settings and thus can lead to…

X-15 Configurations

NASA Image and Video Library

1958-05-06

This scale-model of North American's initial X-15 design was tested in North American and NACA wind tunnels note the conventional tail and fuselage side-tunnels that extend far toward the aircraft nose. North American engineers would determine that the variable wedge-angle stabilizer created a weight issue, and aeronautical testing by Langley engineers confirmed that the side-tunnels made the design less stable.

FAST CHOPPER BUILDING, TRA665, INTERIOR. LOWER (DETECTOR) LEVEL. NOTE BRICKEDIN ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

FAST CHOPPER BUILDING, TRA-665, INTERIOR. LOWER (DETECTOR) LEVEL. NOTE BRICKED-IN WINDOW ON MTR SIDE. USED FOR STORAGE OF LEAD BRICKS AFTER EXPERIMENTAL NEUTRON INSTRUMENTS WERE REMOVED. SIGN SAYS "IN-PROCESS LEAD SOURCE STORAGE." INL NEGATIVE NO. HD-42-2. Mike Crane, Photographer, 3/2004 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

Resuspension of Bed Material and Wave Effects on the Illinois and Upper Mississippi Rivers Caused by Boat Traffic,

DTIC Science & Technology

1975-02-01

banks is also discussed. Aerial color infrared photographs and published information were disouesed’to aid the analysis. -, DD F M nIDITON Of r NOVe IS...boats with consequent erosion of the banks is also discussed. Aerial color infrared photographs and published information were used to aid the analysis...of sediment created by a towboat is shown in the infrared photograph of Figure 2. Note also the evidence of suspended sediment along the side of the

The retention of lacosamide in patients with epilepsy and intellectual disability in three specialised institutions.

PubMed

Brenner, J; Majoie, H J M; van Beek, S; Carpay, J A

2017-11-01

We describe the effectiveness of lacosamide as adjunctive therapy in patients with epilepsy and an intellectual disability. This information is relevant, as few data exist pertaining to this population with a high prevalence of (intractable) epilepsy. We performed a retrospective study in three specialised institutions. Inclusion criteria were (1) focal onset or symptomatic generalized (2) therapy-resistant epilepsy, (3) intellectual disability and (4) residence in a care-facility for people with intellectual disabilities (PWID). The primary outcome variables were the retention rates of lacosamide, estimated through Kaplan-Meier survival analysis. Secondary outcomes were reported seizure control, side effects and clinical factors influencing discontinuation. One hundred and thirty-two patients were included. The median retention time of lacosamide in our cohort was four years. The estimated one-, two- and three-year retention rates of lacosamide were 64%, 57% and 56% respectively. Severity of intellectual disability and seizure type did not influence whether lacosamide was continued. In 48.5% of patients, a reduction of seizure activity was reported. Side effects were at least part of the reason for discontinuing treatment in 26.5% of all patients. Common side effects were tiredness/somnolence (in 30.3%), aggression/agitation (24.2%), and instable gait (15.2%). Five deaths during follow-up were considered unlikely to be related to the use of lacosamide. One patient died unexpectedly within two months of treatment onset, probably this was a case of SUDEP. These retention rates of lacosamide in PWID are similar to rates of previously registered anti-epileptic drugs in PWID. Behavioural side effects were noted in a high proportion compared to the general literature on lacosamide. Other side effects were in line with this literature. Lacosamide seems effective and safe for PWID and refractory epilepsy. Copyright © 2017 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

Labetalol, a new alpha- and beta-adrenoreceptor blocking agent, in hypertension.

PubMed

Hansson, L; Hänel, B

1976-08-01

1Labetalol is a new compound with antagonistic effects at both alpha- and beta-adrenoreceptor sites. 2 When given to 12 hypertensive patients at an average daily dosage of 273 mg for 7 months statistically significant reductions (compared with pretreatment values) in recumbent and standing blood pressure were observed. 3 Treatment has to be withdrawn in one patient because of vivid dreams, and dosage was reduced in one patient because of dizziness. Otherwise no side-effects of importance were noted. 4 It can therefore be concluded that labetalol offers a useful anti-hypertensive effect and that this compound is well tolerated.

Chloral hydrate sedation for magnetic resonance imaging in newborn infants.

PubMed

Finnemore, Anna; Toulmin, Hilary; Merchant, Naz; Arichi, Tom; Tusor, Nora; Cox, David; Ederies, Ash; Nongena, Phumza; Ko, Christopher; Dias, Ryan; Edwards, Anthony D; Groves, Alan M

2014-02-01

The aim of this study was to look for clinically significant adverse effects of chloral hydrate used in a large cohort of infants sedated for magnetic resonance imaging. Case notes of infants who underwent magnetic resonance imaging (MRI) scanning from 2008 to 2010 were reviewed, with patient demographics, sedation dose, comorbidities, time to discharge, and side effects of sedation noted. Four hundred and eleven infants (median [range] postmenstrual age per weight at scan 42 [31(+4) -60] weeks per 3500 g [1060-9900 g]) were sedated with chloral hydrate (median [range] dose 50 [20-80] mg·kg(-1)). In three cases (0.7%), desaturations occurred which prompted termination of the scan. One infant (0.2%) was admitted for additional observation following sedation but had no prolonged effects. In 17 (3.1%) cases, infants had desaturations which were self-limiting or responded to additional inspired oxygen such that scanning was allowed to continue. When adhering to strict protocols, MRI scanning in newborn infants in this cohort was performed using chloral hydrate sedation with a relatively low risk of significant adverse effects. © 2013 John Wiley & Sons Ltd.

Whose Side Are We on and for Whom Do We Write? Notes on Issues and Challenges Facing Those Researching and Evaluating Public Policy

ERIC Educational Resources Information Center

Warren, Jon; Garthwaite, Kayleigh

2015-01-01

Becker (1967) poses the question "Whose side are we on?," a question which has become an enduring part of discussions within social scientific methodology. This paper explores the key issues in Becker's argument and considers its relevance to researchers today, locating this within a consideration of evaluation-based research and policy.…

Laser Line Scan System for UXO Characterization

DTIC Science & Technology

2012-04-01

they geometrically rectified. The Year 2 survey collected LLSS images from seven passes over two separate calibration strings and six passes over two...Microsoft DOS-based software tool. According to the side- by-side comparisons shown in Figure 9, the morphometrics were relatively equal between...survey. Note: The imagery in this figure is not presented at full resolution nor geometrically rectified. LLSS Targets, Pass One 1. Danforth

CORNER OF SUBPILE ROOM: NORTH AND EAST SIDES. STEEL OUTER ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

CORNER OF SUBPILE ROOM: NORTH AND EAST SIDES. STEEL OUTER SHELL HAS BEEN AFFIXED. SIGN SAYS "HERRICK IRON WORKS STEEL, OAKLAND, CALIFORNIA." NOTE CONDUIT FOR FUTURE INSTRUMENTATION. TOP OF STEEL CASE WILL BE LEVEL WITH BASEMENT CEILING. CAMERA FACES SOUTHEAST. INL NEGATIVE NO. 734. Unknown Photographer, 10/6/1950 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

Unsupervised Learning (Clustering) of Odontocete Echolocation Clicks

DTIC Science & Technology

2015-09-30

of their bandwidth. Results on Risso’s dolphins (Grampus griseus), Pacific white-sided dolphins (Lagenorhynchus obliquidens), and Cuvier’s beaked...acoustic encounters to see which ones appeared to be closely related to one another. We noted that some of the Pacific white-sided and Risso’s dolphin ...should be clusterable. The group of odontocetes that we cannot label reliably by their acoustic features, primarily common dolphins (Delphinus spp

Landing Mechanics During Side Hopping and Crossover Hopping Maneuvers in Noninjured Women and Women With Anterior Cruciate Ligament Reconstruction

PubMed Central

Ortiz, Alexis; Olson, Sharon; Trudelle-Jackson, Elaine; Rosario, Martin; Venegas, Heidi L.

2011-01-01

Objective To compare, landing mechanics and electromyographic activity of the lower extremities during side hopping and crossover hopping maneuvers, in noninjured women and women with anterior cruciate ligament (ACL) reconstruction. Design A case-control study. Setting A 3-dimensional motion analysis laboratory. Participants Twenty-eight young women (range, 21–35 years) (15 control subjects and 13 subjects with ACL reconstruction). Patients and Methods All participants performed a side-to-side hopping task that consisted of hopping single-legged 10 times consecutively from side to side across 2 lines marked 30 cm apart on 2 individual force plates. The task was designated as a side hopping when the hop was to the opposite side of the stance leg and as crossover hopping when the hop was toward the side of the stance leg. Main Outcome Measurements Peak hip-/knee-joint angles; peak knee extension/abduction joint moments; electromyographic studies of the gluteus maximus, gluteus medius, rectus femoris, and hamstring muscles; and quadriceps/hamstring co-contraction ratio were compared between the groups by means of 2 × 2 multivariate analysis of variance tests (group × maneuver). Results Noninjured women and women with ACL reconstruction exhibited similar hip-and knee-joint angles during both types of hopping. Hip-joint angles were greater during the crossover hopping in both groups, and knee-joint angles did not differ between the groups or hops. Knee-joint moments demonstrated a significant group × maneuver interaction. Greater knee extension and valgus moments were noted in the control group during crossover hopping, and greater knee abduction moments were noted in the ACL group during side hopping. Electromyographic data revealed no statistically significantly differences between the groups. Conclusions Women with ACL reconstruction exhibited the restoration of functional biomechanical movements such as hip-/knee-joint angles and lower extremity neuromuscular activation during side-to-side athletic tasks. However, not all biomechanical strategies are restored years after surgery, and women who have undergone a procedure such as ACL reconstruction may continue to exhibit knee-joint abduction moments that increase the risk of additional knee injury. PMID:21257128

Effect of lithosperm on thyroidal /sup 32/P uptake at various times of injection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Breneman, W.R.; Zeller, F.J.

These experiments were performed to increase our understanding of possible side effects in the use of extracts of the plant Lithospermum ruderale (LSPM) as a contraceptive. Cold-water extracts of LSPM were used to note possible effects on injected TSH and on endogenous TSH which was increased by the use of propylthiouracil. It was demonstrated that LSPM had a biphasic effect on both endogenous and exogenous TSH activity as measured by chick thyroid /sup 32/P uptake. When given 18h before autopsy, LSPM decreased TSH activity in both, whereas when LSPM was administered 42h or 44h before autopsy, TSH activity was significantlymore » increased.« less

EXPERIMENT - APOLLO 16 (UV)

NASA Image and Video Library

1972-06-06

S72-40821 (21 April 1972) --- An artificially reproduced color enhancement of a ten-minute far-ultraviolet exposure of Earth, taken with a filter which blocks the glow caused by atomic hydrogen but which transmits the glow caused by atomic oxygen and molecular nitrogen. Note that airglow emission bands are visible on the night side of Earth, one roughly centered between the two polar auroral zones and one at an angle to this extending northward toward the sunlit side of Earth. The UV camera was operated by astronaut John W. Young on the Apollo 16 lunar landing mission. It was designed and built at the Naval Research Laboratory, Washington, D.C. EDITOR'S NOTE: The photographic number of the original black & white UV camera photograph, from which this artificially reproduced version was made, is AS16-123-19657.

Acid hydrolysis of Jerusalem artichoke for ethanol fermentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, K.; Hamdy, M.K.

1986-01-01

An excellent substrate for ethanol production is the Jerusalem artichoke (JA) tuber (Helianthus tuberosus). This crop contains a high level of inulin that can be hydrolyzed mainly to D-fructose and has several distinct advantages as an energy source compared to others. The potential ethanol yield of ca. 4678 L/ha on good agricultural land is equivalent to that obtained from sugar beets and twice that of corn. When JA is to be used for ethanol fermentation by conventional yeast, it is first converted to fermentable sugars by enzymes or acids although various strains of yeast were used for the direct fermentationmore » of JA extracts. Fleming and GrootWassink compared various acids (hydrochloric, sulfuric, citric, and phosphoric) and strong cation exchange resin for their effectiveness on inulin hydrolysis and reported that no differences were noted among the acids or resin in their influence on inulin hydrolysis. Undesirable side reactions were noted during acid hydrolysis leading to the formation of HMF and 2-(2-hydroxy acetyl) furan. The HMF at a level of 0.1% is known to inhibit growth and ethanol fermentation by yeast. In this study the authors established optimal conditions for complete acid-hydrolysis of JA with minimum side reactions and maximum sugar-ethanol production. A material balance for the ethanol production was also determined.« less

Working session 1: Tubing degradation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kharshafdjian, G.; Turluer, G.

1997-02-01

A general introductory overview of the purpose of the group and the general subject area of SG tubing degradation was given by the facilitator. The purpose of the session was described as to {open_quotes}develop conclusions and proposals on regulatory and technical needs required to deal with the issues of SG tubing degradation.{close_quotes} Types, locations and characteristics of tubing degradation in steam generators were briefly reviewed. The well-known synergistic effects of materials, environment, and stress and strain/strain rate, subsequently referred to by the acronym {open_quotes}MESS{close_quotes} by some of the group members, were noted. The element of time (i.e., evolution of thesemore » variables with time) was emphasized. It was also suggested that the group might want to consider the related topics of inspection capabilities, operational variables, degradation remedies, and validity of test data, and some background information in these areas was provided. The presentation given by Peter Millet during the Plenary Session was reviewed; Specifically, the chemical aspects and the degradation from the secondary side of the steam generator were noted. The main issues discussed during the October 1995 EPRI meeting on secondary side corrosion were reported, and a listing of the potential SG tube degradations was provided and discussed.« less

Comparative particle recoveries by the retracting rotorod, rotoslide and Burkard spore trap sampling in a compact array

NASA Astrophysics Data System (ADS)

Solomon, W. R.; Burge, H. A.; Boise, J. R.; Becker, M.

1980-06-01

An array comprising 4 intermittent (retracting) rotorods, 3 (“swingshield”) rotoslides and one Burkard (Hirst) automatic volumetric spore trap was operated on an urban rooftop during 70 periods of 9, 15 or 24 hours in late summer. Standard sampling procedures were utilized and recoveries of pollens as well as spores of Alternaria, Epicoccum, Pithomyces and Ganoderma species compared. Differences between paired counts from each sampler type showed variances increasing with levels of particle prevalence (and deposition). In addition, minimal, non-random, side-to-side and intersampler differences were noted for both impactor types. Exclusion of particles between operating intervals by rotoslides and rotorods was virtually complete. Spore trap recoveries for all particle categories, per m3, exceeded those by both impactors. The greatest (7-fold) difference was noted for the smallest type examined ( Ganoderma). For ragweed pollen, an overall spore trap/impactor ratio approached 1.5. Rain effects were difficult to discern but seemed to influence rotoslides least. Overall differences between impactors were quite small but generally favored the rotoslide in this comparison. Our data confirm the relative advantages of suction traps for small particles. Both impactors and spore traps are suited to pollen and large spore collection, and, with some qualification, data from both may be compared.

Investigation of the Effects of High-Intensity, Intermittent Exercise and Unanticipation on Trunk and Lower Limb Biomechanics During a Side-Cutting Maneuver Using Statistical Parametric Mapping.

PubMed

Whyte, Enda F; Richter, Chris; OʼConnor, Siobhan; Moran, Kieran A

2018-06-01

Whyte, EF, Richter, C, O'Connor, S, and Moran, KA. Investigation of the effects of high-intensity, intermittent exercise and unanticipation on trunk and lower limb biomechanics during a side-cutting maneuver using statistical parametric mapping. J Strength Cond Res 32(6): 1583-1593, 2018-Anterior cruciate ligament (ACL) injuries frequently occur during side-cutting maneuvers when fatigued or reacting to the sporting environment. Trunk and hip biomechanics are proposed to influence ACL loading during these activities. However, the effects of fatigue and unanticipation on the biomechanics of the kinetic chain may be limited by traditional discrete point analysis. We recruited 28 male, varsity, Gaelic footballers (21.7 ± 2.2 years; 178.7 ± 14.6 m; 81.8 ± 11.4 kg) to perform anticipated and unanticipated side-cutting maneuvers before and after a high-intensity, intermittent exercise protocol (HIIP). Statistical parametric mapping (repeated-measures analysis of varience) identified differences in phases of trunk and stance leg biomechanics during weight acceptance. Unanticipation resulted in less trunk flexion (p < 0.001) and greater side flexion away from the direction of cut (p < 0.001). This led to smaller (internal) knee flexor and greater (internal) knee extensor (p = 0.002-0.007), hip adductor (p = 0.005), and hip external rotator (p = 0.007) moments. The HIIP resulted in increased trunk flexion (p < 0.001) and side flexion away from the direction of cut (p = 0.038), resulting in smaller (internal) knee extensor moments (p = 0.006). One interaction effect was noted demonstrating greater hip extensor moments in the unanticipated condition post-HIIP (p = 0.025). Results demonstrate that unanticipation resulted in trunk kinematics considered an ACL injury risk factor. A subsequent increase in frontal and transverse plane hip loading and sagittal plane knee loading was observed, which may increase ACL strain. Conversely, HIIP-induced trunk kinematic alterations resulted in reduced sagittal plane knee and subsequent ACL loading. Therefore, adequate hip and knee control is important during unanticipated side-cutting maneuvers.

LPT. Shield test facility assembly and test building (TAN646). East ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

LPT. Shield test facility assembly and test building (TAN-646). East facade of ebor helium wing addition. Camera facing west. Note asbestos-cement siding on stair enclosure and upper-level. Concrete siding at lower level. Metal stack. Monorail protrudes from upper level of south wall at left of view. INEEL negative no. HD-40-7-4 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

1. General view, east end and north side. View to ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. General view, east end and north side. View to southwest toward San Francisco-Oakland Bay Bridge, along general alignment of former Interurban Electric Railway main line. Note truncated catenary support arms on power poles; these originally carried overhead power supply catenary line for the electrically-powered interurban cars. - Interurban Electric Railway Bridge Yard Shop, Interstate 80 at Alameda County Postmile 2.0, Oakland, Alameda County, CA

97. VIEW OF NORTH SIDE OF LANDLINE INSTRUMENTATION ROOM (106), ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

97. VIEW OF NORTH SIDE OF LANDLINE INSTRUMENTATION ROOM (106), LSB (BLDG. 770). EAST ROW OF CABINETS INCLUDES, LEFT TO RIGHT: CABLE DISTRIBUTION UNITS, AUTOPILOT CHECKOUT CONTROLS, AND POWER DISTRIBUTION UNITS. NOTE OVERHEAD DUCTS FOR INSTRUMENT AIR CONDITIONING AND CABLE TRAYS ON EAST, WEST, AND SOUTH WALLS. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

Addressing multigenerational conflict: mutual respect and carefronting as strategy.

PubMed

Kupperschmidt, Betty R

2006-05-31

This article addresses the challenges faced by nurses as they work side-by-side with nurses from a variety of generational cohorts. First a brief overview of the generational characteristics of the four generational cohorts in today's workplace is presented. Next the importance of each nurse using respect and carefronting as antidotes to generational conflict is discussed. Finally the role of nursing leadership in facilitating respect and carefronting is noted.

15. View of southeasterly side of transmitter building no. 102 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. View of southeasterly side of transmitter building no. 102 with TR in middle and small satcom communication dome lower right. Note site well system building to lower right of transmitter building no. 102 southeast corner. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

Rescue pre-operative treatment with Lugol's solution in uncontrolled Graves' disease.

PubMed

Calissendorff, Jan; Falhammar, Henrik

2017-05-01

Graves' disease is a common cause of hyperthyroidism. Three therapies have been used for decades: pharmacologic therapy, surgery and radioiodine. In case of adverse events, especially agranulocytosis or hepatotoxicity, pre-treatment with Lugol's solution containing iodine/potassium iodide to induce euthyroidism before surgery could be advocated, but this has rarely been reported. All patients hospitalised due to uncontrolled hyperthyroidism at the Karolinska University Hospital 2005-2015 and treated with Lugol's solution were included. All electronic files were carefully reviewed manually, with focus on the cause of treatment and admission, demographic data, and effects of iodine on thyroid hormone levels and pulse frequency. Twenty-seven patients were included. Lugol's solution had been chosen due to agranulocytosis in 9 (33%), hepatotoxicity in 2 (7%), other side effects in 11 (41%) and poor adherence to medication in 5 (19%). Levels of free T4, free T3 and heart rate decreased significantly after 5-9 days of iodine therapy (free T4 53-20 pmol/L, P  = 0.0002; free T3 20-6.5 pmol/L, P  = 0.04; heart rate 87-76 beats/min P  = 0.0007), whereas TSH remained unchanged. Side effects were noted in 4 (15%) (rash n  = 2, rash and vomiting n  = 1, swelling of fingers n  = 1). Thyroidectomy was performed in 26 patients (96%) and one was treated with radioiodine; all treatments were without serious complications. Treatment of uncontrolled hyperthyroidism with Lugol's solution before definitive treatment is safe and it decreases thyroid hormone levels and heart rate. Side effects were limited. Lugol's solution could be recommended pre-operatively in Graves' disease with failed medical treatment, especially if side effects to anti-thyroid drugs have occurred. © 2017 The authors.

Should the standard dimethyl sulfoxide concentration be reduced? Results of a European Group for Blood and Marrow Transplantation prospective noninterventional study on usage and side effects of dimethyl sulfoxide.

PubMed

Morris, Curly; de Wreede, Liesbeth; Scholten, Marijke; Brand, Ronald; van Biezen, Anja; Sureda, Anna; Dickmeiss, Ebbe; Trneny, Marek; Apperley, Jane; Chiusolo, Patrizia; van Imhoff, Gustaaf W; Lenhoff, Stig; Martinelli, Giovanni; Hentrich, Marcus; Pabst, Thomas; Onida, Francesco; Quinn, Michael; Kroger, Nicolaus; de Witte, Theo; Ruutu, Tapani

2014-10-01

Dimethyl sulfoxide (DMSO) is essential for the preservation of liquid nitrogen-frozen stem cells, but is associated with toxicity in the transplant recipient. In this prospective noninterventional study, we describe the use of DMSO in 64 European Blood and Marrow Transplant Group centers undertaking autologous transplantation on patients with myeloma and lymphoma and analyze side effects after return of DMSO-preserved stem cells. While the majority of centers continue to use 10% DMSO, a significant proportion either use lower concentrations, mostly 5 or 7.5%, or wash cells before infusion (some for selected patients only). In contrast, the median dose of DMSO given (20 mL) was much less than the upper limit set by the same institutions (70 mL). In an accompanying statistical analysis of side effects noted after return of DMSO-preserved stem cells, we show that patients in the highest quartile receiving DMSO (mL and mL/kg body weight) had significantly more side effects attributed to DMSO, although this effect was not observed if DMSO was calculated as mL/min. Dividing the myeloma and lymphoma patients each into two equal groups by age we were able to confirm this result in all but young myeloma patients in whom an inversion of the odds ratio was seen, possibly related to the higher dose of melphalan received by young myeloma patients. We suggest better standardization of preservation method with reduced DMSO concentration and attention to the dose of DMSO received by patients could help reduce the toxicity and morbidity of the transplant procedure. © 2014 AABB.

Noninvasive lifting of arm, thigh, and knee skin with transcutaneous intense focused ultrasound.

PubMed

Alster, Tina S; Tanzi, Elizabeth L

2012-05-01

Transcutaneous intense focused ultrasound is a novel Food and Drug Administration-approved technology for noninvasive skin tightening of the face and neck. No studies have reported on its safety and effectiveness on nonfacial areas. Eighteen paired areas (6 each) on the upper arms, medial thighs, and extensor knees were randomly treated with two different transducers (4.0 MHz, 4.5-mm focal depth and 7.0 MHz, 3.0-mm focal depth). One side was randomly assigned to receive a single pass (single plane) of microthermal coagulation zones over the involved area with the 4.0 MHz, 4.5-mm-depth transducer, and the contralateral side was assigned to receive consecutive single passes (dual plane) using both transducers (4.0 MHz, 4.5-mm depth followed by 7.0 MHz, 3.0-mm depth). Two independent masked assessors determined clinical improvement scores using comparative standardized photographs obtained at baseline and 3 and 6 months after treatment. Subjective assessments of clinical improvement and side effects of treatment were obtained. Global assessment scores revealed significant improvement in all treated areas, with the upper arms and knees demonstrating more skin lifting and tightening than the thighs. Areas receiving dual-plane treatment had slightly better clinical scores than those receiving single-plane treatment in all three sites. Clinical scores from single-plane and dual-plane treated areas continued to improve between 3 and 6 months after treatment. Side effects were mild and transient and included erythema, warmth, and skin tenderness. Rare focal bruising was noted in two patients on the upper arms that resolved within 7 days. No other side effects were reported or observed. Transcutaneous intense focused ultrasound can be safely and effectively used to improve the clinical appearance (texture and contour) of the upper arms, extensor knees, and medial thighs. © 2012 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.

Efficacy and safety of cross-linked hyaluronic acid single injection on osteoarthritis of the knee: a post-marketing Phase IV study.

PubMed

Bashaireh, Khaldoon; Naser, Ziad; Hawadya, Khaled Al; Sorour, Sorour; Al-Khateeb, Rami Nabeel

2015-01-01

The primary objective of this study was to evaluate the efficacy, safety, and duration of action of viscosupplementation with Crespine® Gel over a 9-month period. The study was a post-marketing Phase IV study. A total of 109 participants with osteoarthritis of the knee (grades 1-4) in the tibio-femoral compartment were recruited in Jordan. Data were collected from each participant during the baseline visit. Each participant received Crespine® Gel injection, and follow-up visits took place at 3 months, 6 months, and 9 months post-injection. An assessment of participants by phone was conducted at 1 month, 2 months, 4 months, 5 months, 7 months, and 8 months post-injection. Western Ontario and McMaster Universities Arthritis Index questionnaires were completed during each visit. A 72-hour visit questionnaire was used to assess the safety of the injection. Statistical analysis included a two-sided 95% confidence interval for the difference between pain scores across visits, and the percent change from baseline was calculated. The full analysis included 84 participants who gave their informed consent and finished the necessary baseline and follow-up visits needed to assess efficacy and safety. Peak improvement was noted at 5 months post-injection, when pain and physical performance scores had decreased to 2.60 and 9.90, respectively, and the stiffness score was 0.33. The peak improvement in stiffness was noted at 8 months post-injection, when the stiffness score had decreased to 0.32. Significant improvements were still apparent at 9 months post-injection, when the pain score was 3.36, the stiffness score was 0.42, and the physical performance score was 11.5. All side effects were local and transient, and included pain, swelling, and redness of the knee. Most side effects were treated. Hyaluronan should be encouraged as an alternative or adjunct treatment to oral analgesics to reduce their required doses, and delay potential future surgical intervention.

48 CFR 41.301 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... costs for the continuation of utility services. (5) A statement noting whether the transformer, or other... supplier, and if the metering is on the primary or secondary side of the transformer. [69 FR 76358, Dec. 20...

[The magnetotherapy of hypertension patients].

PubMed

Ivanov, S G; Smirnov, V V; Solov'eva, F V; Liashevskaia, S P; Selezneva, L Iu

1990-01-01

A study was made of the influence of the constant MKM2-1 magnets on patients suffering from essential hypertension. Continuous action of the magnetic field, created by such magnets, on the patients with stage II essential hypertension was noted to result in a decrease of arterial pressure without the occurrence of any side effects and in a simultaneous reduction of the scope of drug administration. Apart from that fact, magnetotherapy was discovered to produce a beneficial effect on the central hemodynamics and microcirculation. The use of the MKM2-1 magnets may be regarded as a feasible method of the treatment of essential hypertension patients at any medical institution.

A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy.

PubMed

Liu, Dora; Ahmet, Alexandra; Ward, Leanne; Krishnamoorthy, Preetha; Mandelcorn, Efrem D; Leigh, Richard; Brown, Jacques P; Cohen, Albert; Kim, Harold

2013-08-15

Systemic corticosteroids play an integral role in the management of many inflammatory and immunologic conditions, but these agents are also associated with serious risks. Osteoporosis, adrenal suppression, hyperglycemia, dyslipidemia, cardiovascular disease, Cushing's syndrome, psychiatric disturbances and immunosuppression are among the more serious side effects noted with systemic corticosteroid therapy, particularly when used at high doses for prolonged periods. This comprehensive article reviews these adverse events and provides practical recommendations for their prevention and management based on both current literature and the clinical experience of the authors.

Wind-Tunnel Investigation of the Effect of Vertical Position of the Wing on the Side Flow in the Region of the Vertical Tail

DTIC Science & Technology

1941-04-01

measured with a bank of pitot -yaw tubes-connected to a direct-reading multiple-tube manometer. The- bank of pitot -yaw tubes was so mounted as- to...neutral and deflected 60°. These Surveys were made on a cross-tunnel line 2.26 inches above the fuselage center line, and the pitot -yaw tubes were...Langley Field-, 7a-., January 30, 1941. NACA Technical Note So. 804 17 REFERENCES 1. Pearson, Henry A., and Jones, Robert T. : Theoretical

Are Medications Involved in Vision and Intracranial Pressure Changes Seen in Spaceflight

NASA Technical Reports Server (NTRS)

Wotring, Virginia E.

2015-01-01

The Food and Drug Association Adverse Event Reports (FDA AER) from 2009-2011 were used to create a database from millions of known and suspected medication-related adverse events among the general public. Vision changes, sometimes associated with intracranial pressure changes (VIIP), have been noted in some long duration crewmembers. Changes in vision and blood pressure (which can subsequently affect intracranial pressure) are fairly common side effects of medications. The purpose of this study was to explore the possibility of medication involvement in crew VIIP symptoms.

Comparing Efficacy and Side Effects of Memantine vs. Risperidone in the Treatment of Autistic Disorder.

PubMed

Nikvarz, Nikvarz; Alaghband-Rad, Javad; Tehrani-Doost, Mehdi; Alimadadi, Abbas; Ghaeli, Padideh

2017-01-01

Introduction: This study was aimed to compare the efficacy and side effects of memantine, an antagonist of the NMDA receptor of glutamate, with risperidone given the fact that glutamate has been noted for its possible effects in the pathogenesis of autism. Risperidone, an atypical antipsychotic, has been approved by FDA for the management of irritability associated with autism. Methods: 30 children, aged 4-17 years, entered an 8-week, randomized trial. Patients were randomly assigned to receive either risperidone or memantine. Autism Behavior Checklist (ABC), Childhood Autism Rating Scale (CARS), Clinical Global Impressions - Improvement (CGI-I) and Clinical Global Impression-Severity (CGI-S) scales were used to assess behavioral symptoms of the patients. Results: Both risperidone and memantine reduced the scores of 4 subscales of ABC as well as the 10-item and the total score of CARS significantly. However, differences between the 2 drugs in the scores of each evaluating scale were not found to be significant. Relatively, larger number of patients on risperidone showed "very much improvement" when assessed by CGI-I scale when compared with those on memantine. Discussion and conclusion: The present study suggests that memantine may have beneficial effects in the treatment of many core symptoms of autism. Therefore, memantine may be considered as a potential medication in the treatment of those autistic children who do not respond or cannot tolerate side effects of risperidone. © Georg Thieme Verlag KG Stuttgart · New York.

2. EXTERIOR FRONT (SOUTHEAST) SIDE OF BUILDING 117 SHOWING MAIN ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. EXTERIOR FRONT (SOUTHEAST) SIDE OF BUILDING 117 SHOWING MAIN RESIDENTIAL STREET IN LOWER FOREGROUND, CEMENT-LAID ROCK RETAINING WALL IN FRONT OF HOUSE, AND CONCRETE STEPS AND WALKWAY TO FRONT PORCH AND DOOR. NOTE SLIDING GLASS DOOR REPLACEMENT FOR ORIGINAL DOOR WHICH HAS SUBSEQUENTLY BEEN REMODELED BACK TO A SINGLE ENTRY DOOR. VIEW TO NORTHWEST. - Bishop Creek Hydroelectric System, Plant 4, Worker Cottage, Bishop Creek, Bishop, Inyo County, CA

15. Detail, lower chord connection point on downstream side, showing ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. Detail, lower chord connection point on downstream side, showing pinned connection of lower chord eye bars, laced vertical compression member, diagonal eye bar tension members, turnbuckled diagonal counters, and floor beam. Note also timber floor stringers supported by floor beam, and exposed ends of timber deck members visible at left above lower chord eye bar. View to northwest. - Dry Creek Bridge, Spanning Dry Creek at Cook Road, Ione, Amador County, CA

1. EXTERIOR VIEW OF ELM CITY PLANT (A. FRANCIS WALKER, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. EXTERIOR VIEW OF ELM CITY PLANT (A. FRANCIS WALKER, 1905-07) FROM SECOND AVENUE ON OPPOSITE SIDE OF ENTRANCE. THIS STRUCTURE WAS ORIGINALLY BUILT AS THE ELM CITY COTTON MILL OF CALLAWAY MILLS. NOTE RESERVOIR IN FOREGROUND. THIS PHOTOGRAPH IS THE LEFT SIDE OF A PANORAMA VIEW THAT INCLUDES HAER Nos. GA-128-2 AND GA-128-3. - Elm City Cotton Mill, 1000 Elm Street, La Grange, Troup County, GA

Detail view of the forward section, port side, of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view of the forward section, port side, of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the removal of the Forward Reaction Control System Module from the nose section, the ground-support window covers and the strongback attached to the payload bay door. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

2. Credit BG. View down dust ditch at northeast side ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Credit BG. View down dust ditch at northeast side of A Street, looking north northwest in "the loop". Note culverts used to give vehicular and pedestrian access to buildings northeast of A Street, some foundations of which may be seen at right of view. Structures in background belong to Jet Propulsion Laboratory Edwards Facility. - Edwards Air Force Base, North Base, Dust Ditch System, Traversing North Base, Boron, Kern County, CA

Convex Hemiepiphysiodesis: Posterior/anterior in-situ Versus Posterior-only With Pedicle Screw Instrumentation: An Experimental Simulation in Immature Pigs.

PubMed

Bekmez, Senol; Demirkiran, Halil G; Yilmaz, Guney; Akel, Ibrahim; Atilla, Pergin; Muftuoglu, Sevda Fatma; Yazici, Muharrem; Alanay, Ahmet

2016-12-01

Experimental study. Convex growth arrest (CGA) has been commonly used in the treatment of long-sweeping congenital deformities of the immature spine. As there are major drawbacks about the anterior procedure in the conventional CGA method, a new modification has been documented that using only posterior spinal approach with pedicle screw instrumentation. The aim of the study was to compare posterior-only CGA using pedicle screws with combined anterior/posterior in-situ CGA for the findings in histologic, radiologic, and manual palpation examinations in an immature pig model. Twelve 10-weeks old pigs were grouped into 2. In group 1, posterior-only, pedicle screw instrumented CGA was performed on the left side of L1-L4 vertebrae. In group 2, conventional combined posterior and anterior CGA was performed to the left side of L1-L4 vertebrae without instrumentation. All animals were killed twelve weeks after surgery. T11-L5 segments were en-bloc resected and radiologic, histologic, and manual palpation examinations were done. Marked scoliotic (12.2±2.5 and 9.2±1.3 in group 1 and 2, respectively) and kyphotic (11.2±1.0 degrees for the group 1 and 12±5.2 degrees for the group 2, respectively) deformities were noted in both groups, which were caused by hemiepiphysiodesis effect. Anterior and posterior parts of group 2 and posterior part of group 1 demonstrated fusion in histologic and radiologic analyzes. In anterior part of the group 1, marked narrowing on the disk spaces and thinning of growth plates were noted in radiologicg examination, chondrocyte degeneration, and newly-formed bone trabeculae in disk-space were noted in histological examination. In manual palpation, no motion was detected in group 1 and motion was detected in only one segment of one animal in group 2. Anterior growth of the vertebrae can be controlled by application of posterior transpedicular screws and rod. Such an effect can eliminate the need for anterior surgical intervention in convex hemiepiphysiodesis procedures. The instrumented CGA technique provides a satisfactory epiphysiodesis effect both anteriorly and posteriorly, as previously demonstrated by clinical studies.

Synthesis of Nanosilver Particles in the Texture of Bank Notes to Produce Antibacterial Effect

NASA Astrophysics Data System (ADS)

Lari, Mohammad Hossein Asadi; Esmaili, Vahid; Naghavi, Seyed Mohammad Ebrahim; Kimiaghalam, Amir Hossein; Sharifaskari, Emadaldin

Silver particles show antibacterial and antiseptic properties at the nanoscale. Such properties result from an alteration in the binding capacity of silver atoms in bits of less than 6.5nm which enables them to kill harmful organisms. Silver nanoparticles are now the most broadly used agents in the area of nanotechnology after carbon nanotubes. Given that currency bills are one of the major sources of bacterial disseminations and their contamination has recently been nominated as a critical factor in gastrointestinal infections and possibly colon cancers, here we propose a new method for producing antibacterial bank notes by using silver nanoparticles. Older bank notes are sprayed with acetone to clean the surface. The bank note is put into a petri-dish containing a solution of silver nitrate and ammonia so that it is impregnated. The bank notes are then reduced with the formaldehyde gas, which penetrates its texture and produces silver nanoparticles in the cellulose matrix. The side products of the reactions are quickly dried off and the procedure ends with the drying of the bank note. The transmission electron microscope (TEM) images confirmed the nanoscale size range for the formed particles while spectroscopy methods, such as XRD, provided proof for the metallic nature of the particles. Bacterial challenge tests then showed that no colonies of the three tested bacterium (Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa survived on the sample after a 72h incubation period. This study has provided a method for synthesizing silver NPs directly into the texture of fabrics and textiles (like that of bank notes) which can result in lower production costs, making the use of silver NPs economically beneficial. The method, specifically works on the fabric of bank notes, suggesting a method to tackle the transmission of bacteria through bank notes. Moreover, this study is a testament to the strong antibacterial nature of even low concentrations of silver NPs.

FAST CHOPPER BUILDING, TRA665. CAMERA FACING NORTH. NOTE BRICKEDIN WINDOW ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

FAST CHOPPER BUILDING, TRA-665. CAMERA FACING NORTH. NOTE BRICKED-IN WINDOW ON RIGHT SIDE (BELOW PAINTED NUMERALS "665"). SLIDING METAL DOOR ON COVERED RAIL AT UPPER LEVEL. SHELTERED ENTRANCE TO STEEL SHIELDING DOOR. DOOR INTO MTR SERVICE BUILDING, TRA-635, STANDS OPEN. MTR BEHIND CHOPPER BUILDING. INL NEGATIVE NO. HD42-1. Mike Crane, Photographer, 3/2004 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

PERSPECTIVE VIEW FROM NORTHEAST OF 8 HILLSIDE ROAD (ROW HOUSES). ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PERSPECTIVE VIEW FROM NORTHEAST OF 8 HILLSIDE ROAD (ROW HOUSES). NOTE UTILITY CLOSETS AND GARAGE ENTRANCE FOR "SERVICE" SIDE OF STRUCTURE. - Old Greenbelt, Crescent Road and Southway, Greenbelt, Prince George's County, MD

Spatial anatomy of the round ligament, gallbladder, and intrahepatic vessels in patients with right-sided round ligament of the liver.

PubMed

Ibukuro, Kenji; Takeguchi, Takaya; Fukuda, Hozumi; Abe, Shoko; Tobe, Kimiko

2016-11-01

To analyze the vascular structure of the liver in patients with a right-sided round ligament. We reviewed 16 patients with a right-sided round ligament and 3 polysplenia and situs inversus patients with a left-sided round ligament who underwent multidetector row CT with contrast media. The patient population consisted of 13 men and 6 women (mean 62 years). We analyzed the axial and volume-rendered images for the location of the round ligament, gallbladder, portal veins, hepatic veins, and hepatic artery. The following imaging findings for the patients with polysplenia and situs inversus were horizontally reversed. The prevalence of a right-sided round ligament with and without polysplenia was 75 and 0.11 %, respectively. The gallbladder was located to the right, below, and left of the round ligament in 27.7, 38.8 and 33.3 %, respectively. Independent branching of the right posterior portal vein was noted in 57.8 %. PV4 was difficult to identify in 36.8 %. The middle hepatic vein was located to the left of the round ligament. Two branching patterns for the lateral and medial branches of the right anterior hepatic artery were noted: the common (44.4 %) and separated types (55.5 %). Both of the right anterior hepatic artery and portal vein ramified into two segments; the lateral segment with many branches and the medial segment with a few branches. The right-sided round ligament divided the right anterior section into the lateral and medial segments based on the portal vein and hepatic artery anatomy.

Hydronephrosis in Acute Uncomplicated Appendicitis.

PubMed

Schok, T; Austen, S; Lewicz, R B C B; Zande, F H R van der; Peters, N A L R; Janzing, H M J

2015-01-01

Right-sided hydronephrosis as a sign of appendicitis occurs rarely in the literature. To our knowledge, this is the first published account of the occurrence of right-sided hydronephrosis as a result of uncomplicated appendicitis. We describe a 15 year old patient referred to the emergency department with suspected appendicitis. Additional ultrasound examination showed a right-sided hydronephrosis. This finding was discussed with the urologist who noted the hydronephrosis as a chance finding. Because of persistent clinical suspicion of appendicitis, a diagnostic laparoscopy was performed. A retrocaecal appendicitis with secondary hydronephrosis was found. Right-sided hydronephrosis may be a sign of acute uncomplicated (retrocaecal) appendicitis. It is important to keep sight of these findings, especially in view of the emphasis on imaging techniques in the current Dutch guideline on appendicitis.

Jupiter Night and Day

NASA Technical Reports Server (NTRS)

2001-01-01

Day and night side narrow angle images taken on January 1, 2001 illustrating storms visible on the day side which are the sources of visible lightning when viewed on the night side. The images have been enhanced in contrast. Note the two day-side occurrences of high clouds, in the upper and lower parts of the image, are coincident with lightning storms seen on the darkside. The storms occur at 34.5 degrees and 23.5 degrees North latitude, within one degree of the latitudes at which similar lightning features were detected by the Galileo spacecraft. The images were taken at different times. The storms' longitudinal separation changes from one image to the next because the winds carrying them blow at different speeds at the two latitudes.

Pulsed Vincristine Therapy in Steroid-Resistant Nephrotic Syndrome

PubMed Central

Thalgahagoda, Shenal; Abeyagunawardena, Shamali; Jayaweera, Heshan; Karunadasa, Umeshi Ishanthika

2017-01-01

Steroid-resistant nephrotic syndrome (SRNS) poses a therapeutic challenge for the paediatric nephrologist. As relentless progression to renal failure occurs with continued proteinuria, such patients will be treated with different cytotoxic medications with variable success rates and side-effects. We present here our findings on administering the anticancer drug vincristine for SRNS patients at a single centre in Sri Lanka. Methods. Between 2002 and 2007, fifty-four children presenting with steroid and cyclophosphamide resistance were treated with vincristine at 1.5 mg/m2 in weekly intravenous pulses for 8 weeks along with a tapering steroid regimen of 6 months. All patients were closely followed up for 5 years. Results. Of the 54 patients 39 were males and 15 were females (age range 3.5–11.6 years, median 6.1 years). At the end of the treatment course, 21 patients achieved complete remission while 7 had partial remission and no response was seen in 26 patients. Sustained remission at 6, 12, 24, and 60 months were 15 (27.78%), 11 (20.37%), 9 (16.67%), and 7 (12.96%), respectively. Most side-effects observed were reversible and no serious side-effects were noted during vincristine therapy. Conclusion. Although its therapeutic mechanisms in nephrotic syndrome are still not elucidated, vincristine appears to be a potent alternative that could be considered for treating SRNS. PMID:28630858

Impact of an early education multimedia intervention in managing nutrition-related chemotherapy side effects: a pilot study.

PubMed

Thompson, Julie; Silliman, Kathryn; Clifford, Dawn E

2013-12-01

The purpose of the educational intervention was to measure changes in knowledge, perceived benefit of nutrition, and perceived self efficacy in handling side effects of chemotherapy before and after viewing a 15 minute DVD among patients with cancer. A convenience sample of 14 (4 male, 10 female, 61 ± 9 years) patients with cancer, early to chemotherapy, participated in the study. Participants completed a survey with demographic, knowledge items, and perceived health belief and self efficacy statements; viewed the DVD; and were then sent home with a one page handout. Two weeks after the nutrition education intervention, a second survey was completed including an item about tips used. Change was measured using paired t-test and wilcoxon signed rank tests. The mean score on the four knowledge items significantly increased (p < 0.05). No significant differences were noted in statements intended to evaluate changes in perceived health beliefs. However, perceived knowledge and skills related to managing side effects increased (p < 0.05). All participants responded that the DVD was informative and most (n = 11, 79%) responded that it was useful. The majority reported (n = 10, 71%) a tip they used from the DVD. This short multimedia nutrition education intervention was found primarily to increase knowledge and could form a useful component of counseling services for patients undergoing chemotherapy.

Protective effect of A/H1N1 vaccination in immune-mediated disease--a prospectively controlled vaccination study.

PubMed

Adler, Sabine; Krivine, Anne; Weix, Janine; Rozenberg, Flore; Launay, Odile; Huesler, Juerg; Guillevin, Loïc; Villiger, Peter M

2012-04-01

To assess the 2009 influenza vaccine A/H1N1 on antibody response, side effects and disease activity in patients with immune-mediated diseases. Patients with RA, SpA, vasculitis (VAS) or CTD (n = 149) and healthy individuals (n = 40) received a single dose of adjuvanted A/H1N1 influenza vaccine. Sera were obtained before vaccination, and 3 weeks, 6 weeks and 6 months thereafter. A/H1N1 antibody titres were measured by haemagglutination inhibition (HAI) assay. Seroprotection was defined as specific antibody titre ≥ 1 : 40, seroconversion as 4-fold increase in antibody titre. Titres increased significantly in patients and controls with a maximum at Week 3, declining to levels below protection at Month 6 (P < 0.001). Seroprotection was more frequently reached in SpA and CTD than in RA and VAS (80 and 82% and 57 and 47%, respectively). There was a significantly negative impact by MTX (P < 0.001), rituximab (P = 0.0031) and abatacept (P = 0.045). Other DMARDs, glucocorticoids and TNF blockers did not significantly suppress response (P = 0.06, 0.11 and 0.81, respectively). A linear decline in response was noted in patients with increasing age (P < 0.001). Disease reactivation possibly related to vaccination was suspected in 8/149 patients. No prolonged side effects or A/H1N1 infections were noted. The results show that vaccination response is a function of disease type, intensity and character of medication and age. A single injection of adjuvanted influenza vaccine is sufficient to protect a high percentage of patients. Therefore, differential vaccination recommendations might in the future reduce costs and increase vaccination acceptance.

Interaction of arginine, lysine, and guanidine with surface residues of lysozyme: implication to protein stability.

PubMed

Shah, Dhawal; Shaikh, Abdul Rajjak

2016-01-01

Additives are widely used to suppress aggregation of therapeutic proteins. However, the molecular mechanisms of effect of additives to stabilize proteins are still unclear. To understand this, we herein perform molecular dynamics simulations of lysozyme in the presence of three commonly used additives: arginine, lysine, and guanidine. These additives have different effects on stability of proteins and have different structures with some similarities; arginine and lysine have aliphatic side chain, while arginine has a guanidinium group. We analyze atomic contact frequencies to study the interactions of the additives with individual residues of lysozyme. Contact coefficient, quantified from contact frequencies, is helpful in analyzing the interactions with the guanidine groups as well as aliphatic side chains of arginine and lysine. Strong preference for contacts to the additives (over water) is seen for the acidic followed by polar and the aromatic residues. Further analysis suggests that the hydration layer around the protein surface is depleted more in the presence of arginine, followed by lysine and guanidine. Molecular dynamics simulations also reveal that the internal dynamics of protein, as indicated by the lifetimes of the hydrogen bonds within the protein, changes depending on the additives. Particularly, we note that the side-chain hydrogen-bonding patterns within the protein differ with the additives, with several side-chain hydrogen bonds missing in the presence of guanidine. These results collectively indicate that the aliphatic chain of arginine and lysine plays a critical role in the stabilization of the protein.

Evaluation of the Effectiveness of an Alar Transfixion Suture for the Correction of a Vestibular Web and Alar-Facial Groove: A Photogrammetric Analysis.

PubMed

Han, Kihwan; Oh, Sangho; Choi, Jaehoon; Park, Sang Woo

2018-05-01

Alar transfixion sutures are commonly used for vestibular web correction. The purpose of this study was to evaluate the long-term results of the use of alar transfixion sutures in patients with a unilateral cleft lip nasal deformity using photogrammetric analysis. The study included 42 patients who were divided into child and adult groups. A total of 4 measurement items were evaluated from a basal view by photogrammetry using standardized clinical photographic techniques preoperatively, immediately postoperatively, 3 months postoperatively, and 6 months postoperatively. When the preoperative and last postoperative values were compared, no significant changes in any measurement items were noted in the adult group. In the child group, the proportional index (the ratio of the cleft side to the noncleft side) of the alar slope line inclination was significantly increased, but other measurement items showed no significant change. When the measurement items were compared between time points, no significant changes in any measurement items were noted in the adult group. In the child group, the proportional indexes of the alar length, the width between the subnasale and the alare, and the webbing degree were significantly decreased immediately postoperatively compared with the preoperative values. However, these significant changes were diminished at 3 months postoperatively. The proportional index of the alar slope line inclination was significantly increased at 3 months postoperatively compared with the preoperative value, but the significant change was diminished at 6 months postoperatively. The alar transfixion suture procedure is not effective for correcting a vestibular web and alar-facial groove.

Cryolipolysis for fat reduction and body contouring: safety and efficacy of current treatment paradigms.

PubMed

Ingargiola, Michael J; Motakef, Saba; Chung, Michael T; Vasconez, Henry C; Sasaki, Gordon H

2015-06-01

Cryolipolysis is a nonsurgical technique for localized fat reduction. With the increased risk of complications from more invasive methods such as liposuction, cryolipolysis presents a promising method for nonsurgical body contouring. This study presents a systematic review of the available clinical data, with an emphasis on the efficacy, methods, safety, and complications of cryolipolysis. To identify clinical studies that assessed outcomes of cryolipolysis, a systematic review of the MEDLINE and Cochrane databases was performed with the search algorithm cryolipolysis OR cool sculpting OR fat freezing OR lipocryolysis. The primary literature search returned 319 articles. After inclusion criteria were applied and additional articles were idenfied via manual review of article references, 19 studies were selected for review. Average reduction in caliper measurement ranged from 14.67 percent to 28.5 percent. Average reduction by ultrasound ranged from 10.3 percent to 25.5 percent. No significant impact on lipid levels or liver function tests after cryolipolysis treatments was noted in any study. Only mild, short-term side effects, such as erythema, swelling, and pain, were noted. Paradoxical adipose hyperplasia was described in one patient. Cryolipolysis is a promising procedure for nonsurgical fat reduction and body contouring and presents a compelling alternative to liposuction and other, more invasive methods. This procedure appears to be safe in the short term, with a limited side effect profile, and results in significant fat reduction when used for localized adiposities. It remains unclear whether posttreatment manual massage and multiple treatments in the same anatomic area enhance the efficacy of cryolipolysis.

Family planning and the controversial contraceptives.

PubMed

Dias Saxena, F

1995-01-01

India was one of the first countries in the world to launch a national family planning program in an apparent effort to help women gain access to birth control measures and reduce population growth. Family planning acquired a different meaning and emphasis in the 1960s, however, when a clause in the US PL480 wheat import policy demanded that India speed its implementation of birth control measures if the country wanted food aid. Women in India were therefore expected to consume contraceptives with dangerous and unknown side effects in order to quality the country for food aid. Women rejected this stipulation. By the 1980s, it was acknowledged that family planning programs in India had failed to produce a decline in the birth rate and that no sign of change was on the horizon despite the investment of substantial funds to that end, the input of expert assistance, and the establishment of appropriate infrastructure in the country. Experts and policy makers blamed women for having misused the pill and sought alternative methods which would not require user compliance. Norplant and norethisterone enanthate (Net-en) were subsequently developed. Policymakers, experts, and the press have now been clamoring for the right to conduct Norplant trials despite reported side effects. The drug's ability to prevent pregnancy is more important for family planning experts. The author notes that the emphasis has been upon contraceptive methods for women instead of men because men were not expected to take responsibility for family planning. She also notes that feminists are opposed to Norplant and Net-en, and hopes that the government withdraws them from the market.

The Other Side of the Hidden Curriculum: Correspondence Theories and the Labor Process.

ERIC Educational Resources Information Center

Apple, Michael W.

1980-01-01

Discusses the inadequacy of correspondence as a theory of the relationship both among all social institutions and between the school and other powerful socioeconomic forces. Notes implications for educational action. (Author/MK)

Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study.

PubMed

Garg, Vijay Kumar; Sinha, Surabhi; Sarkar, Rashmi

2009-01-01

Many clinicians have used glycolic acid (GA) peels for facial acne, scarring, and hyperpigmentation, mainly in lighter skin types. Salicylic-mandelic acid combination peels (SMPs) are a newer modality, and there have been no well-controlled studies comparing them with other conventional agents. To compare the therapeutic efficacy and tolerability of 35% GA peels and 20% salicylic-10% mandelic acid peels in active acne and post-acne scarring and hyperpigmentation. Forty-four patients with facial acne and post-acne scarring and hyperpigmentation were divided into two groups, with one receiving GA peels and the other SMPs at fortnightly intervals for six sessions. The treating physician performed objective evaluation of treatment outcomes. The patients, the treating physician, and an independent observer made subjective assessments. Side effects of both agents were also noted. Both the agents were effective, but SMPs had a higher efficacy for most active acne lesions (p<.001) and hyperpigmentation (p<.001). Side effects were also lesser with SMPs. Both the agents were effective and safe in Indian patients, with SMPs being better for active acne and post-acne hyperpigmentation.

A novel approach for analyzing data on recurrent events with duration to estimate the combined cumulative rate of both variables over time.

PubMed

Bhattacharya, Sudipta

2018-06-01

Recurrent adverse events, once occur often continue for some duration of time in clinical trials; and the number of events along with their durations is clinically considered as a measure of severity of a disease under study. While there are methods available for analyzing recurrent events or durations or for analyzing both side by side, no effort has been made so far to combine them and present as a single measure. However, this single-valued combined measure may help clinicians assess the wholesome effect of recurrence of incident comprising events and durations. Non-parametric approach is adapted here to develop an estimator for estimating the combined rate of both, the recurrence of events as well as the event-continuation, that is the duration per event. The proposed estimator produces a single numerical value, the interpretation and meaningfulness of which are discussed through the analysis of a real-life clinical dataset. The algebraic expression of variance is derived, asymptotic normality of the estimator is noted, and demonstration is provided on how the estimator can be used in the setup of testing of statistical hypothesis. Further possible development of the estimator is also noted, to adjust for the dependence of event occurrences on the history of the process generating recurrent events through covariates and for the case of dependent censoring.

STS-65 Japanese Payload Specialist Mukai at CCT side hatch during training

NASA Image and Video Library

1993-11-22

STS-65 Japanese Payload Specialist Chiaki Mukai takes a break from training at the Johnson Space Center (JSC). Wearing a training version of the orange launch and entry suit (LES), Mukai stands at the crew compartment trainer (CCT) side hatch in the Mockup and Integration Laboratory (MAIL) Bldg 9NE. Note the crew escape system (CES) pole device extending out the side hatch which would accommodate crewmembers in bailout from a troubled spacecraft. Mukai represents the National Space Development Agency (NASDA) of Japan and will serve as a payload specialist aboard Columbia, Orbiter Vehicle (OV) 102, during the STS-65 International Microgravity Laboratory 2 (IML-2) mission.

STS-65 Japanese Payload Specialist Mukai at CCT side hatch during training

NASA Technical Reports Server (NTRS)

1993-01-01

STS-65 Japanese Payload Specialist Chiaki Mukai takes a break from training at the Johnson Space Center (JSC). Wearing a training version of the orange launch and entry suit (LES), Mukai stands at the crew compartment trainer (CCT) side hatch in the Mockup and Integration Laboratory (MAIL) Bldg 9NE. Note the crew escape system (CES) pole device extending out the side hatch which would accommodate crewmembers in bailout from a troubled spacecraft. Mukai represents the National Space Development Agency (NASDA) of Japan and will serve as a payload specialist aboard Columbia, Orbiter Vehicle (OV) 102, during the STS-65 International Microgravity Laboratory 2 (IML-2) mission.

An Environmental Survey of Canton Atoll Lagoon, 1973

DTIC Science & Technology

1976-06-01

isolated /’e)ll~opora heads. Observation track perpendicular to shoreline. Numnerous sea 4 ~ urchins (L~Ivnomo’ra sp.) in surf zone. 200 m - ,-observation...narrowest and shallowest point Is approximately 150 m wide and 5 m deep. In his original field notes, E. H -. Bryan. Jr. I(notes at Whitney South Sea ...a height ot over 5 in1 above sea leyel. 1’ho turning basin wits cleared and the deep channel was prouhubly dredged front the lagoon side, Later, the

Exploring vocal recovery after cranial nerve injury in Bengalese finches.

PubMed

Urbano, Catherine M; Peterson, Jennifer R; Cooper, Brenton G

2013-02-08

Songbirds and humans use auditory feedback to acquire and maintain their vocalizations. The Bengalese finch (Lonchura striata domestica) is a songbird species that rapidly modifies its vocal output to adhere to an internal song memory. In this species, the left side of the bipartite vocal organ is specialized for producing louder, higher frequencies (≥2.2kHz) and denervation of the left vocal muscles eliminates these notes. Thus, the return of higher frequency notes after cranial nerve injury can be used as a measure of vocal recovery. Either the left or right side of the syrinx was denervated by resection of the tracheosyringeal portion of the hypoglossal nerve. Histologic analyses of syringeal muscle tissue showed significant muscle atrophy in the denervated side. After left nerve resection, songs were mainly composed of lower frequency syllables, but three out of five birds recovered higher frequency syllables. Right nerve resection minimally affected phonology, but it did change song syntax; syllable sequence became abnormally stereotyped after right nerve resection. Therefore, damage to the neuromuscular control of sound production resulted in reduced motor variability, and Bengalese finches are a potential model for functional vocal recovery following cranial nerve injury. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

33 CFR 110.115 - Santa Barbara Harbor, Calif.

Code of Federal Regulations, 2011 CFR

2011-07-01

...; excluding a fairway 225 feet wide, 100 feet from each side of and parallel to the Navy pier. Note: Fore and.... 2106 for yachts and small craft of such size and alignment as permitted by the harbor master. ...

33 CFR 110.115 - Santa Barbara Harbor, Calif.

Code of Federal Regulations, 2010 CFR

2010-07-01

...; excluding a fairway 225 feet wide, 100 feet from each side of and parallel to the Navy pier. Note: Fore and.... 2106 for yachts and small craft of such size and alignment as permitted by the harbor master. ...

Perspective view of the west elevation looking from the southwest ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Perspective view of the west elevation looking from the southwest (Eighth Street side; note U.S. Patent Office in background) - United States General Post Office, Between Seventh, Eighth, E, & F Streets, Northwest, Washington, District of Columbia, DC

Looking west at bridge crane and concrete apron on south ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Looking west at bridge crane and concrete apron on south side of Machine Shop (Bldg. 163). Note overhead steam pipes - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, Machine Shop, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

Hydronephrosis in acute uncomplicated appendicitis.

PubMed

Schok, T; Austen, S; Lewicz, R B C B; van der Zande, F H R; Peters, N A L R; Janzing, H M J

2015-01-01

Right-sided hydronephrosis as a sign of appendicitis occurs rarely in the literature. To our knowledge, this is the first published account of the occurrence of right-sided hydronephrosis as a result of uncomplicated appendicitis. We describe a 15 year old patient referred to the emergency department with suspected appendicitis. Additional ultrasound examination showed a right-sided hydronephrosis. This finding was discussed with the urologist who noted the hydronephrosis as a chance finding. Because of persistent clinical suspicion of appendicitis, a diagnostic laparoscopy was performed. A retrocaecal appendicitis with secondary hydronephrosis was found. Right-sided hydronephrosis may be a sign of acute uncomplicated (retrocaecal) appendicitis. It is important to keep sight of these findings, especially in view of the emphasis on imaging techniques in the current Dutch guideline on appendicitis. Copyright© Acta Chirurgica Belgica.

Jupiter Night and Day

NASA Image and Video Library

2001-01-23

Day and night side narrow angle images taken on January 1, 2001 illustrating storms visible on the day side which are the sources of visible lightning when viewed on the night side. The images have been enhanced in contrast. Note the two day-side occurrences of high clouds, in the upper and lower parts of the image, are coincident with lightning storms seen on the darkside. The storms occur at 34.5 degrees and 23.5 degrees North latitude, within one degree of the latitudes at which similar lightning features were detected by the Galileo spacecraft. The images were taken at different times. The storms' longitudinal separation changes from one image to the next because the winds carrying them blow at different speeds at the two latitudes. http://photojournal.jpl.nasa.gov/catalog/PIA02878

Refined applications of the collapse of the wave function

NASA Astrophysics Data System (ADS)

Stodolsky, L.

2015-05-01

In a two-part system, the collapse of the wave function of one part can put the other part in a state which would be difficult or impossible to achieve otherwise, in particular, one sensitive to small effects in the "collapse" interaction. We present some applications to the very symmetric and experimentally accessible situations of the decays ϕ (1020 )→KoKo , ψ (3770 )→DoDo, or ϒ (4 s )→BoBo , involving the internal state of the two-state Ko, Do, or Bo mesons. The collapse of the wave function occasioned by a decay of one member of the pair (away side) fixes the state vector of that side's two-state system. Bose-Einstein statistics then determines the state of the recoiling meson (near side), whose evolution can then be followed further. In particular, the statistics requirement dictates that the "away side" and "near side" internal wave functions must be orthogonal at the time of the collapse. Thus a C P violation in the away side decay implies a complementary C P impurity on the near side, which can be detected in the further evolution. The C P violation so manifested is necessarily direct C P violation, since neither the mass matrix nor time evolution was involved in the collapse. A parametrization of the direct C P violation is given, and various manifestations are presented. Certain rates or combination of rates are identified which are nonzero only if there is direct C P violation. The very explicit and detailed use made of the collapse of the wave function makes the procedure interesting with respect to the fundamentals of quantum mechanics. We note an experimental consistency test for our treatment of the collapse of the wave function, which can be carried out by a certain measurement of partial decay rates.

[Scarless surgery: a vision becoming reality?].

PubMed

Lamm, Sebastian H; Zerz, Andreas; Steinemann, Daniel C

2016-04-13

As minimal invasive abdominal surgery became established in the last decades, further minimization of the surgical access is in the focus now. Although laparoscopic instruments and camera systems become diminished in size there is still a need for a minilaparotomy for extraction and anastomosis of organs. NOTES (Natural orifice transluminal endoscopic surgery) aims to avoid this minilaparotomy. Consequently, laparoscopic-assisted procedures become pure laparoscopic surgery. The transvaginal access is the most common performed NOTES procedure. The acceptance in women is high. The feasibility of NOTES cholecystectomy is scientifically proofed. The procedure is associated with less pain than the common four-port laparoscopic surgery and does not interfere with the sexual well-being. There are no access-related infections; the abdominal wound infection and incisional hernia rate are low. In left sided colonic resection the transrectal access makes NOTES available for both genders.

Dynamo room (compartment A21) with view of port side, art ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Dynamo room (compartment A-21) with view of port side, art electrical generator in background. Note cables, speaking tubes and steering crank arm at top center of photograph. These rise through an armored tube to the Conning Tower. The electrical distribution board at left is a reproduction of the board as it may have looked in the 1920's. Reproduction was done in the 1970's and the 1980's. (015) - USS Olympia, Penn's Landing, 211 South Columbus Boulevard, Philadelphia, Philadelphia County, PA

GREAT II (Upper Mississippi River. Guttenberg, Iowa to Saverton, Missouri). Side Channel Work Group Appendix

DTIC Science & Technology

1980-12-01

is current during normal river stage. The graduations in this category are wide- spread, ranging frcm fast flowing watercourses with high banks to...channel category on the other. They may be former side channels that have been cut off, or that have only intermittent flows in them. They may be...navigation project certainly is a contributor by providing a deep channel and an abundance of beaches. Karaki and Van Hoften noted that small, fast

Computer Animated Representations to Optically Observe Numerical Evaluations (CARTOONE). Computer Generated Animations of Solid Bodies.

DTIC Science & Technology

1983-04-01

20. it diferent hrem Report) IS. SUPPLEMENTARY NOTES It. KEY WORDS (Conthu on revere* side if neceeemy md Identify by bock number) Computer Generated...ABSTRACT (Continue an revere side If neceeary end Identity by block mmbr) This report documents the work done in-house by personnel of ASD/ENFTC to develop a...unfamiliar with the system. This report contains a User’s Guide and documents the work done to develop CARTOONE. The work was accomplished from

Should the United States Army Have a Professional General Staff?

DTIC Science & Technology

1987-03-23

SUPPLEMENTARY NOTES IS. KEY WORDS (Continue on reverse side if necessary and ldentlfy by block number) 20L ABSTRACT (Ceatu m orevere N nc wmy acd...Identify by block nember) 2ontinued on reverse side. 1’,..,* OR A 7 17 ED#-no,* OF INOV 6S IS OBSOLETE OF PG , ,.,. 3 .o o. ., N s. O. ETE SECURITY...Genius for 5 War: The German Army and General Staff 1807 - 1945. I do not intend to address org~ n ~zation. Most governments and * defense

Port side view of the Orbiter Discovery from an elevated ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Port side view of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the ground support hardware known as Strongbacks attached to the payload bay doors, the crew access hatch below the name Discovery on the forward section of the Orbiter and the removed Orbiter Maneuvering System/Reaction Control System pod from the aft (tai) section. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

View looking aft along the starboard side of the midfuselage ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View looking aft along the starboard side of the mid-fuselage of the Orbiter Discovery. This view shows the wing profile as it intersects with the fuselage. Also note in the foreground the panels protecting the Reinforced Carbon-Carbon leading edge of the wing. This view was taken from the service platform in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Evolving S Boxes with Reduced Differential Power Analysis Susceptibiltiy

DTIC Science & Technology

2016-12-02

coefficient [PEB+14,PPE+14]. Note that in the 4-bit case they could simultaneously maximize both cryptanalytic and side channel prop- erties [ PEP +14]. When its... PEP +14, PMMB15]; which makes sense for criteria of similar types, or when carefully weighting an understood trade-off. Work that combined...cryptanalytic and side channel properties failed to explore the trade- off [PEB+14,PPE+14, PEP +14,PMMB15], other than to provide loose bounds [MMS13]. Instead, it

Search for volatiles on icy satellites. I. Europa

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, R.H.; Cruikshank, D.P.; Tokunaga, A.T.

1988-05-01

NASA IRTF reflectance spectra of unprecedented precision, obtained for the leading and trailing sides of Europa, are presently noted to no longer show the apparent absorptions seen in 1980 and 1985. It is presently suggested that if the weak absorptions seen in the 1980 and 1985 data are real, they may indicate the transient spectroscopic presence of a molecular component on Europa's trailing side that differs from the water ice known to be the dominant constituent of the surface. 33 references.

Lipo-PGE1, a new lipid-encapsulated preparation of prostaglandin E1: placebo-and prostaglandin E1-controlled multicenter trials in patients with diabetic neuropathy and leg ulcers.

PubMed

Toyota, T; Hirata, Y; Ikeda, Y; Matsuoka, K; Sakuma, A; Mizushima, Y

1993-11-01

Several clinical trials have shown that prostaglandin E1 (PGE1) is effective in treating peripheral occlusive vascular disease, but not definitely for diabetic neuropathy. We developed a new preparation of PGE1 incorporated in lipid microspheres (lipo-PGE1) that was designed to accumulate at vascular lesions. The effect of lipo-PGE1 (10 micrograms/day) was compared with placebo and the normal dose of a free PGE1 preparation (PGE1-CD, 40 micrograms/day) in two studies (double-blind and well-controlled) which enrolled 364 diabetic patients with neuropathy and/or leg ulcers. The drugs were given intravenously (bolus or drip infusion) for 4 weeks. Clinical improvement was noted in 61.6% of the lipo-PGE1 group and 30.0% of the placebo group in Trial 1 (p < 0.01), while the figures were 58.3% in the lipo-PGE1 group and 37.1% in the PGE1-CD group in Trial 2 (p < 0.01). Leg ulcers became smaller in the lipo-PGE1 groups in both trials (p < 0.01). In Trial 2, motor conduction velocity improved in the lipo-PGE1 group (p = 0.016). Side effects occurred in few patients receiving lipo-PGE1 or placebo, but more patients developed local side effects in the PGE1-CD group (p < 0.01). Thus, bolus intravenous injection of lipo-PGE1 improved diabetic neuropathy and leg ulcers with minimal side effects.

Use of strontium-90 plesiotherapy for the treatment of a lingual plasmacytoma in a dog.

PubMed

Ware, K; Gieger, T

2011-04-01

A 12-year-old, 25 kg, intact male St Bernard crossbreed was presented for treatment of a 538 mm ulcerated tumour on the dorsal tongue. Fine-needle aspiration cytology revealed a plasmacytoma. The dog staged negative for evidence of local metastatic or systemic disease. Histopathology confirmed the diagnosis. Treatment with one 150 Gy dose of radiation delivered with strontium-90 plesiotherapy was performed. Side effects were not noted and there was no visible evidence of tumour remaining at 2 months and 1 year after therapy. © 2011 British Small Animal Veterinary Association.

A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy

PubMed Central

2013-01-01

Systemic corticosteroids play an integral role in the management of many inflammatory and immunologic conditions, but these agents are also associated with serious risks. Osteoporosis, adrenal suppression, hyperglycemia, dyslipidemia, cardiovascular disease, Cushing’s syndrome, psychiatric disturbances and immunosuppression are among the more serious side effects noted with systemic corticosteroid therapy, particularly when used at high doses for prolonged periods. This comprehensive article reviews these adverse events and provides practical recommendations for their prevention and management based on both current literature and the clinical experience of the authors. PMID:23947590

Io meteorology - How atmospheric pressure is controlled locally by volcanos and surface frosts

NASA Technical Reports Server (NTRS)

Ingersoll, Andrew P.

1989-01-01

The present modification of the Ingersoll et al. (1985) hydrodynamic model of the SO2 gas sublimation-driven flow from the day to the night side of Io includes the effects of nonuniform surface properties noted in observational studies. Calculations are conducted for atmospheric pressures, horizontal winds, sublimation rates, and condensation rates for such surface conditions as patchy and continuous frost cover, volcanic venting, surface temperature discontinuities, subsurface cold trapping, and the propagation of insolation into the frost. While pressure is found to follow local vapor pressure away from the plumes, it becomes higher inside them.

How to think about nuclear war

DOE Office of Scientific and Technical Information (OSTI.GOV)

Luttwak, E.N.

1982-08-01

Mr. Luttwak, a professional defense consultant, observes the arguments of nuclear freeze proponents can be refuted on both strategic and moral grounds. The freeze concept is illogical, he notes, because it is political systems - not state boundaries - that separate sides and because the Warsaw Pact countries are more heavily armed than the North Atlantic Treaty Organization (NATO) countries. An important factor keeping NATO forces at a disadvantage is their defensive orientation, which keeps forces militarily diffuse and dependent on nuclear weapons and preemptive action as a deterrent. Mr. Luttwak feels the shock effect of any use of nuclearmore » weapons would probably shorten a war rather than expand it because of the instinct for survival on both sides; further only nuclear weapons have this awesome power to deter. The proposal for universal disarmament under world government control is not a serious one, he thinks, and reflects an indifference to the possibility of a long non-nuclear war. The effect would be to trade the risk of nuclear death for the inevitability of many non-nuclear casualties. (DCK)« less

8. Close view of sign showing the pediment, top portion ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Close view of sign showing the pediment, top portion with letter "C" and middle portion with letters "H-I-C" (Note: side sheet metal panels are missing) - Chicago Theater, 175 North State Street, Chicago, Cook County, IL

Anesthetic activity and bio-guided fractionation of the essential oil of Aloysia gratissima (Gillies & Hook.) Tronc. in silver catfish Rhamdia quelen.

PubMed

Benovit, Simone C; Silva, Lenise L; Salbego, Joseânia; Loro, Vania L; Mallmann, Carlos A; Baldisserotto, Bernardo; Flores, Erico M M; Heinzmann, Berta M

2015-09-01

This work aimed to determine the efficacy of the essential oil of A. gratissima as anesthetic for silver catfish, and to perform the bio-guided fractionation of essential oil aiming to isolate compounds responsible for the noted effects. Fish were submitted to anesthesia bath with essential oil, its fractions and isolated compounds to determine time of anesthetic induction and recovery. Eugenol (50 mg L(-1)) was used as positive control. Essential oil of A. gratissima was effective as an anesthetic at concentrations of 300 to 900 mg L(-1). Fish presented involuntary muscle contractions during induction and recovery. The bio-guided fractionation of essential oil furnished E-(-)-pinocamphone, (-)-caryophyllene oxide, (-)-guaiol and (+)-spathulenol. E-(-)-pinocamphone caused the same side effects observed for essential oil. (-)-Caryophyllene oxide, (-)-guaiol and (+)-spathulenol showed only sedative effects at proportional concentrations to those of the constituents in essential oil. (+)-Spathulenol (51.2 mg L(-1)) promoted deep anesthesia without side effects. A higher concentration of (+)-spathulenol, and lower or absent amounts ofE-(-)-pinocamphone could contribute to increase the activity and safety of the essential oil of A. gratissima. (+)-Spathulenol showed potent sedative and anesthetic activities in silver catfish, and could be considered as a viable compound for the development of a new anesthetic.

From EUCLID to Ptolemy in English Crop Circles

NASA Astrophysics Data System (ADS)

Hawkins, G. S.

1997-12-01

The late Lord Soli Zuckerman, science advisor to several British governments, encouraged the author, an astronomer, to test the theory that all crop circles were made by hoaxers. Within the hundreds of formations in Southern England he saw a thread of surprising historical content at the intellectual level of College Dons. One diagram in celestial mechanics involved triple conjunctions of Mercury, Venus and Mars every 67 2/3 years. Ptolemy's fourth musical scale, tense diatonic, occurred in the circles during the period 1978-88. Starting on E, Ptolemaic ratios make our perfect diatonic scale of white notes on the keyboard of the piano or church organ. For separated circles the ratio was given by diameters, and for concentric circles it was diameters squared. A series of rotationally symmetric figures began in 1988 which combined Ptolemy's ratios with Euclid's theorems. In his last plane theorem, Euclid (Elements 13,12) proved that the square on the side of an equilateral triangle is 3 times the square on the circum-circle radius -- diatonic note G(2). From the 1988 figure one can prove the square on the side is 16/3 times the square on the semi-altitude, giving note F(3). Later rotational figures over the next 5 years led to diatonic ratios for the hexagon, square and triangle. They gave with the exactness of Euclidean theorems the notes F, C(2) and E(2), and they are the only regular polygons to do so. Although these 4 crop theorems derive from Euclid, they were previously unknown as a set in the literature, nor had the Ptolemaic connection been published. Professional magazines asked the readers to provide a fifth theorem that would generate the above 4 theorems, but none was forthcoming. Ultimately the cicle makers showed knowledge of this generating theorem using a 200-ft design at Litchfield, Hampshire. After 1993, rotationally symmetric geometries continued to appear, but with much more complicated patterns. One design showed 6 crescent moons in a hexagon with cusps set on 2 concentric circles defining the note A(2). Here the mathematical level required application of Ptolemy's famous theorem of chords to confirm the A(2) ratio of exactly 10/3. The chords were the side of a hexagon joined to the side of a pentagon. We confirm Zuckerman's suggestion that there is a strong thread of expertise in the phenomenon worthy of scientific interest, and it spans a 20-year period. He asks: Why do they use a wheat field, and "how do they maintain their hidden identities?" Their type of knowledge rests in the past, and is not frequently found in the contemporary educational system.

Augmentin duo™ in the treatment of childhood blepharokeratoconjunctivitis.

PubMed

Cehajic-Kapetanovic, Jasmina; Kwartz, Jeff

2010-01-01

To report the use of Augmentin Duo 400/57 (GlaxoSmithKline, Middlesex, UK) in the treatment of childhood blepharokeratoconjunctivitis (BKC). This is a retrospective interventional case series. The case notes of 7 consecutive patients treated with Augmentin Duo 400/57 for BKC during 18 months were reviewed. Diagnostic criteria for BKC were blepharitis including recurrent chalazia and meibomian gland dysfunction, eyelid margin telangiectasia and facial rosacea, recurrent episodes of chronic red eye, photophobia, watering, punctate superficial keratopathy, corneal neovascularization, and corneal ulcers. Seven children (age range: 6 to 14 years) were diagnosed as having BKC. All children received systemic Augmentin Duo 400/57 and showed considerable improvement within the first month of therapy. Six children had no recurrences during a mean follow-up of 6 months. No patients experienced any side effects from this treatment. Augmentin Duo 400/57 has not previously been reported in the treatment of BKC in children. In this case series, Augmentin Duo 400/57 proved to be at least as effective as current treatments with systemic erythromycin or doxycycline with the advantage of a twice-daily dosage and a superior side-effect profile. Copyright 2010, SLACK Incorporated.

Preinjury and postinjury running analysis along with measurements of strength and tendon length in a patient with a surgically repaired Achilles tendon rupture.

PubMed

Silbernagel, Karin Grävare; Willy, Richard; Davis, Irene

2012-06-01

Case report. The Achilles tendon is the most frequently ruptured tendon, and the incidence of Achilles tendon rupture has increased in the last decade. The rupture generally occurs without any preceding warning signs, and therefore preinjury data are seldom available. This case represents a unique opportunity to compare preinjury running mechanics with postinjury evaluation in a patient with an Achilles tendon rupture. A 23-year-old female sustained a right complete Achilles tendon rupture while playing soccer. Running mechanics data were collected preinjury, as she was a healthy participant in a study on running analysis. In addition, patient-reported symptoms, physical activity level, strength, ankle range of motion, heel-rise ability, Achilles tendon length, and running kinetics were evaluated 1 year after surgical repair. During running, greater ankle dorsiflexion and eversion and rearfoot abduction were noted on the involved side postinjury when compared to preinjury data. In addition, postinjury, the magnitude of all kinetics data was lower on the involved limb when compared to the uninvolved limb. The involved side displayed differences in strength, ankle range of motion, heel rise, and tendon length when compared to the uninvolved side 1 year after injury. Despite a return to normal running routine and reports of only minor limitations with running, considerable changes were noted in running biomechanics 1 year after injury. Calf muscle weakness and Achilles tendon elongation were also found when comparing the involved and uninvolved sides.

Diary of an astronaut: examination of the remains of the late Israeli astronaut Colonel Ilan Ramon's Crew Notebook recovered after the loss of NASA's space shuttle Columbia.

PubMed

Brown, Sharon; Sin-David, Laser

2007-05-01

Two months after the fatal re-entering into the Earth's atmosphere of Columbia flight STS-107, the remains of Israeli astronaut Colonel Ilan Ramon's Crew Notebook were found strewn in a field in San Augustine County, TX. The random pile of papers was found to have survived the calamity of the Shuttle's disintegration remarkably well. Most of the papers recovered were torn and/or washed out to varying degrees but only mildly charred around the edges. The sheets of paper could be categorized into four groups: Group I: eight sides of paper written while in space in black ink and in pencil--Ramon's personal diary; the writing on these eight sides of paper survived well and is only missing where the pages were torn. Small fragments found in the field were physically matched to holes in the pages thus locating their original positions in the text. Group II: six sides of technical preparation notes written by Ramon before the mission. The writing on these pages was washed out entirely, but much of it was visualized using infrared luminescence. Group III: eight sides of personal notes prepared by Ramon before the mission written in blue ink. The writing on these pages was barely visible to the naked eye and not visualized by infrared luminescence, but was made largely legible by digital enhancement imaging. Group IV: a few sides of printed technical information. These pages were mostly intact and were not examined at length as they contained standard printed material. After completion of examinations at the Questioned Document Laboratory of the Israel Police, the diary was transferred to the Paper Conservation Department of the Israel Museum for preservation and strengthening treatments.

View of east end of north elevation of Building No. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View of east end of north elevation of Building No. 23. Note walkway in foreground. Looking south-southwest - Easter Hill Village, Building No. 23, North side of South Twenty-sixth Street, east of Corto Square, Richmond, Contra Costa County, CA

Streetscape showing north sides of five of eight Medical Detachment ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Streetscape showing north sides of five of eight Medical Detachment Barracks on Ramp No. 5. Note that Building No. 9966-B on right has a wooden frame sun porch. This Standard Ward construction is different than most of the other Medical Detachment Barracks, which are all- brick. On the opposite side of this building, the construction is all-brick (Building No. 9966-A, not shown). Buildings No. 9967-B and 9968-B (not shown) also have wooden frame sun porches. Other buildings in photo are, on right, the north B-sides of Buildings Nos. 9965, 9964, 9963 and 9962. On left is Building No. 9971-A on Ramp No. 6. Corridor A is visible in far distance. - Madigan Hospital, Medical Detachment Barracks, Bounded by Wilson & McKinley Avenues & Garfield & Lincoln Streets, Tacoma, Pierce County, WA

Right sided weakness with right subdural hematoma: motor deafferentation of left hemisphere resulted in paralysis of the right side.

PubMed

Derakhshan, Iraj

2009-08-01

A right handed man with trauma to the head was admitted with headache and seizures. A severe right sided weakness was noted after a blunt trauma to the right side of his head. MRI of brain revealed a right-sided subdural hematoma and a normal left hemisphere and downstream motor pathways. Bimanual simultaneous drawing and manual reaction times indicated that the patient was right hemispheric in laterality of his major hemisphere. The right sided weakness in this patient was due to temporary transcallosal disconnection (diaschisis) of the minor hemisphere (left, in this case) from the excitatory signals arising from those structures of his major hemisphere devoted to movements occurring on nondominant side, transmitted via the corpus callosum to his left hemisphere. This case draws attention to disparity between neural and behavioral handedness (laterality of major hemisphere versus that of the preferred hand). Drawing longer lines by the left hand in simultaneous bimanual tasks and a slower simple reaction time to central visual stimuli by the ostensible dominant hand permitted lateralization of the major hemisphere to the right. Thus, the neurally nondominant side (right) lagged behind the dominant (left) by an interval equal to interhemispheric transfer time.

Treatment of good-prognosis polyarteritis nodosa and Churg-Strauss syndrome: comparison of steroids and oral or pulse cyclophosphamide in 25 patients. French Cooperative Study Group for Vasculitides.

PubMed

Gayraud, M; Guillevin, L; Cohen, P; Lhote, F; Cacoub, P; Deblois, P; Godeau, B; Ruel, M; Vidal, E; Piontud, M; Ducroix, J P; Lassoued, S; Christoforov, B; Babinet, P

1997-12-01

Twenty-five patients with good-prognosis polyarteritis nodosa or Churg-Strauss syndrome entered a prospective, randomized, multicentre study comparing two treatments: either oral corticosteroids and oral cyclophosphamide (CY; 2 mg/kg/day) for 1 yr (group A), or oral corticosteroids and monthly i.v. CY pulses (0.6 g/m2) (group B) for 1 yr. The objective was to determine the optimal CY regimen. Judgement criteria were the efficacy of the treatment in controlling the disease and the development of side-effects. Among the 25 patients who could be analysed, complete recovery was achieved with the experimental treatment in 9/12 patients in group A and 10/13 patients in group B. Two patients in each group relapsed after the end of therapy and were well controlled by corticosteroids or other drugs. One failure occurred in each group. The mean follow-up was 60.8 +/- 14.5 months after the beginning of the treatment. Side-effects associated with the administration of CY and steroids were noted 27 times in group A vs 14 times in group B (not significant). The oldest patient in these series (group B) died of pneumonia. No superiority in terms of efficacy could be established between the two regimens; however, the number of patients included was too small to conclude definitively. Toxic side-effects were significantly more frequent in women (P < 0.02). The high number of adverse effects leads us to recommend pulse over oral CY and an overall lowering of the doses of immunosuppression.

Dexmedetomidine versus midazolam as adjuvants to intrathecal bupivacaine: A clinical comparison.

PubMed

Shukla, Usha; Prabhakar, Tallamraju; Malhotra, Kiran; Srivastava, Dheeraj

2016-01-01

Trials are being carried out to identify an adjuvant to intrathecal bupivacaine that preferably potentiates postoperative analgesia. This prospective, randomized, double-blind study was aimed to compare the onset and duration of sensory and motor block, postoperative analgesia and adverse effects of dexmedetomidine or midazolam given with 0.5% hyperbaric bupivacaine for spinal anesthesia. A total of 80 patients, scheduled for vaginal hysterectomies, were randomly allocated to Group D (n = 40) to receive intrathecally 3.0 mL 0.5% hyperbaric bupivacaine +5 ug dexmedetomidine in 0.5 mL of normal saline; and Group M (n = 40) to receive 3 mL of 0.5% hyperbaric bupivacaine +2 mg midazolam in 0.4 mL (5 mg/mL) +0.1 mL normal saline. The onset, duration of sensory and motor block, time to first postoperative analgesia and side effects were noted. Power and Sample size (PS) version 3.0.0.34 was used for power and sample size calculation. Statistical analysis was performed using Microsoft (MS) Office Excel software with the Student's t-test and Chi-square test (level of significance P = 0.05). Duration of sensory, motor blockade and time to the first requirement of analgesia were significantly higher in Group D. Postoperative visual analog scale was significantly less in Group D than Group M. Both groups were similar with respect to sedation, hemodynamic variables and side-effects. Intrathecal dexmedetomidine was better adjuvant than midazolam as it produces significantly longer duration of sensory block, reduced doses of postoperative analgesic agents with comparable side-effects.

Long pulsed dye laser treatment of facial wrinkles.

PubMed

Tay, Yong-Kwang; Khoo, Boo-Peng; Tan, Eileen; Kwok, Colin

2004-11-01

The flashlamp pulsed dye laser has been used in the treatment of rhytids. To evaluate the efficacy of the long pulsed dye laser in the treatment of mild to moderate wrinkles in Asian patients. Wrinkles on one half of the face in 10 subjects were treated with the long pulsed dye laser (595 nm, 10 mm spot size, 10 ms, 7 J/cm2, 40 ms spray, 40 ms delay, single-pass, 30% overlap) with the other side serving as a control. A total of three treatments were given at 2 monthly intervals. The following sites were treated: periorbital area, six patients; forehead, two patients; cheek, two patients. No preoperative anesthesia or postoperative treatment were used. Clinical photographs were taken before and after each treatment, and analysis was undertaken through photographic evaluation by non-treating physicians. At 2 months after the last treatment, the clinical improvement of rhytids was noted in all patients compared with baseline. Four subjects had mild improvement (< or = 25%), five had moderate improvement (26-50%) and one had marked improvement (51-75%). The periorbital area was more responsive to treatment compared with the other sites. No clinical changes were noted in the control areas. No adverse effects were reported except for transient mild erythema in two patients which lasted for up to an hour. Nine patients were somewhat satisfied with the treatment and one was highly satisfied. All wanted the other half of the face to be treated. Treatment with a non-ablative 595 nm flashlamp pulsed dye laser can lead to mild to moderate clinical improvement in class I-II rhytids with minimal to no side effects in patients with darker skin types.

Characterizing Physician Listening Behavior During Hospitalist Handoffs using the HEAR Checklist

PubMed Central

Greenstein, Elizabeth A.; Arora, Vineet M.; Staisiunas, Paul G.; Banerjee, Stacy S.; Farnan, Jeanne M.

2015-01-01

Background The increasing fragmentation of healthcare has resulted in more patient handoffs. Many professional groups, including the Accreditation Council on Graduate Medical Education and the Society of Hospital Medicine, have made recommendations for safe and effective handoffs. Despite the two-way nature of handoff communication, the focus of these efforts has largely been on the person giving information. Objective To observe and characterize the listening behaviors of handoff receivers during hospitalist handoffs. Design Prospective observational study of shift change and service change handoffs on a non-teaching hospitalist service at a single academic tertiary care institution. Measurements The “HEAR Checklist”, a novel tool created based on review of effective listening behaviors, was used by third party observers to characterize active and passive listening behaviors and interruptions during handoffs. Results In 48 handoffs (25 shift change, 23 service change), active listening behaviors (e.g. read-back (17%), note-taking (23%), and reading own copy of the written signout (27%)) occurred less frequently than passive listening behaviors (e.g. affirmatory statements (56%) nodding (50%) and eye contact (58%)) (p<0.01). Read-back occurred only 8 times (17%). In 11 handoffs (23%) receivers took notes. Almost all (98%) handoffs were interrupted at least once, most often by side conversations, pagers going off, or clinicians arriving. Handoffs with more patients, such as service change, were associated with more interruptions (r= 0.46, p<0.01). Conclusions Using the “HEAR Checklist”, we can characterize hospitalist handoff listening behaviors. While passive listening behaviors are common, active listening behaviors that promote memory retention are rare. Handoffs are often interrupted, most commonly by side conversations. Future handoff improvement efforts should focus on augmenting listening and minimizing interruptions. PMID:23258389

Effect of management practices and animal age on incidence of mastitis in Nili Ravi buffaloes.

PubMed

Ali, Tariq; Rahman, Abdur; Qureshi, Muhammand Subhan; Hussain, Muhammad Tariq; Khan, Muhammad Shauib; Uddin, Siraj; Iqbal, Muhammad; Han, Bo

2014-10-01

Buffalo is an economically important dairy animal in South Asia but mostly ignored in research priorities. In this retrospective study, the effect of management practices and age of animal on the incidence of mastitis in Nili Ravi buffaloes was investigated. A total of 1,560 quarters of buffaloes (n = 390) were screened by visual examination of the udder and milk (clinical mastitis) and California mastitis test (subclinical mastitis). Household data was collected on a predesigned questionnaire and analyzed. The prevalence of subclinical mastitis, clinical mastitis, and blind quarters was 41.8, 13.6, and 9.7 %, respectively. The highest prevalence was noted in the hind quarters and left side as compared to that in the forequarters and right side. This data significantly (p < 0.05) supported the idea that larger herd size has more chances of mastitis, with the highest prevalence (40, 32, and 27 %) in the large, medium, and small herds, respectively. Stage of lactation was significantly (p < 0.01) involved in mastitis, and the highest incidence (43.3 %) was noted in early lactation. Milk production of lactating buffaloes that ranged 6-10 l/day showed a higher rate of mastitis occurrence (p < 0.05). The cleanliness condition of a farm also contributed significantly. Animal age significantly affected the incidence of mastitis. Results revealed that age of the animal has a positive correlation (R (2) = 0.772) with mastitis. This study concluded that some factors alone or in combination with other factors influence significantly the occurrence of mastitis, and to minimize the infection, these factors should be considered. The outcome of the study will be valuable for policy-making for positive management practices and implementation of preventive measures.

Temporary implant-supported prosthesis for immediate loading according to a chair-side concept: technical note and results from 37 consecutive cases.

PubMed

Ostman, Pär-Olov; Hellman, Mats; Sennerby, Lars; Wennerberg, Ann

2008-05-01

During the last years, focus has been paid to implant treatment using immediate function protocols, and different approaches to provide patients with temporary constructions have been presented. Most of these techniques involve dental technicians producing the temporary construction, for example, rebuilding existing dentures, acrylic bridges, etc. The purpose of this prospective clinical study was to evaluate the clinical outcome of a chair-side technique of a cost-effective temporary prosthesis. Fixture survival rate and risk of temporary bridge failure were analyzed. Thirty-seven partially or totally edentate patients (18 female and 19 male; mean age: 66.7 years) treated with chair-side manufactured temporary restorations (QuickBridge, BIOMET 3i, Palm Beach, Fl, USA) for immediate loading have been evaluated. The prostheses extended from two unit bridges supported by two implants to full-arch construction supported by six implants. The temporary prostheses were monitored from the day of surgery and delivery to the time of replacement with a permanent prosthetic construction 3 to 6 months later. No implants were lost during the observation time. One (3%) temporary prosthesis fractured and additional two (6%) loosened during the follow-up time. The study indicated that the tested chair-side concept for manufacturing of temporary prosthesis for immediate loading of dental implants is a viable approach.

A prospective, split-face, randomized study of the efficacy and safety of a novel fractionated intense pulsed light treatment for melasma in Asians.

PubMed

Yun, Woo Jin; Lee, Sang Min; Han, Ji Su; Lee, Sang Hyung; Chang, Seo Youn; Haw, Sik; Lee, Jung Bok; Won, Chong Hyun; Lee, Mi Woo; Choi, Jee Ho; Chang, Sung Eun

2015-01-01

Intense pulsed light (IPL) has been reported to effectively treat melasma in previous studies, but an aggravation of pigmentation was noted. Fractionated IPL is a novel technique in which microsecond-domain fractionated pulses are delivered to the target area. To compare the safety and efficacy of low-fluency, frequently scheduled fractionated IPL and conventional IPL for melasma treatment. This was a 14-week, split-face study in which 30 Asian women were treated with weekly fractionated IPL on one side of the face and biweekly conventional IPL on the other side. The non-inferiority of a weekly fractionated IPL regimen to a biweekly conventional IPL regimen was verified by a lower margin of the 95% confidence interval for the difference in the Melasma Area and Severity Index (MASI) change from baseline of 2.61 for each side. This value was greater than the previously determined non-inferiority margin of -2.68 (P < 0.025). On the fractionated IPL side, the modified MASI score decreased continuously, but in the conventional IPL group, the MASI score rebounded during the treatment course. Fractionated IPL shows moderate efficacy as a melasma treatment and is therefore a good alternative to conventional IPL as there is no indication of melasma exacerbation. Fractionated IPL can also be used as a maintenance treatment for melasma.

Therapeutic effect of praziquantel against Taeniasis asiatica.

PubMed

Ohnishi, Kenji; Sakamoto, Naoya; Kobayashi, Ken-ichiro; Iwabuchi, Sentaro; Nakamura-Uchiyama, Fukumi

2013-08-01

Eight Japanese adult patients infected with Taenia asiatica were treated with a single 600 mg dose of praziquantel. The patients' body weights ranged from 47 to 87 kg (mean 67.1±12.7 kg). All patients expelled the strobila after taking praziquantel, and all of them were free from proglottids the day after praziquantel administration, hence all patients were considered to be cured. No side effects due to praziquantel were noted. Although the number of patients is small, our results indicate that praziquantel is a drug of choice for the treatment of taeniasis asiatica and that a single dose of 7-13 mg/kg (9.3±1.9 mg/kg) is effective. Copyright © 2013 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Medical Malpractice Litigation Following Arthroscopic Surgery.

PubMed

Shah, Kalpit N; Eltorai, Adam E M; Perera, Sudheesha; Durand, Wesley M; Shantharam, Govind; Owens, Brett D; Daniels, Alan H

2018-04-10

Our study aims to analyze a variety of factors involving malpractice lawsuits following arthroscopy, focusing on reasons for lawsuit and establishing predictors for the outcome of the lawsuit. Two legal databases, VerdictSearch and Westlaw, were queried for arthroscopic cases in adult patients. For all included cases, clinical and demographic data were recorded. The effects of plaintiff demographics, joint involved, lawsuit allegation, case ruling, and size of indemnity payments were assessed. Of the 240 included cases, 62 (26%) resulted in plaintiff verdict, 160 (67%) resulted in defense verdict, and 18 (8%) were settled without trial. Plaintiff demographics (age and sex) had no effect on the case ruling. There was no statistical difference between indemnity awards for plaintiff verdicts ($1,013,494) and settled cases ($848,331; P = .13). Patient death was noted in 20 cases (8.3%); a significantly higher proportion of these cases were settled versus went to trial (P = .0022), including 19 patients (95%) who had knee arthroscopy and 16 deaths (80%) resulting from a pulmonary embolus. Plaintiff verdict or settlement were seen significantly more frequently for vascular complications and wrong-sided surgery. Alternatively, defense verdicts followed lawsuits alleging surgeon technical error. Wrong-sided surgery, retained instruments, deep venous thrombosis, and postoperative infections were seen at a significantly higher proportion after knee arthroscopy than after arthroscopy of other joints. Similarly, neurological injury was significantly associated with elbow and hip arthroscopy, while allegations of technical error by the surgeon and block-related complications were associated with shoulder arthroscopy. Plaintiff verdict or settlement were seen for vascular complications and wrong-sided surgery, while defense verdicts followed lawsuits alleging surgeon technical error and block-related complications. We also identified types of allegations that were associated with arthroscopy of different joints. All but one case of patient death (20 cases) were noted to involve knee arthroscopy, and an overwhelming majority resulted due to a pulmonary embolism. This information helps the arthroscopic surgeon better counsel patients and employ strategies to mitigate preventable complications. Level IV, case series. Copyright © 2018 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

Efficacy and safety of cross-linked hyaluronic acid single injection on osteoarthritis of the knee: a post-marketing Phase IV study

PubMed Central

Bashaireh, Khaldoon; Naser, Ziad; Hawadya, Khaled Al; Sorour, Sorour; Al-Khateeb, Rami Nabeel

2015-01-01

Purpose The primary objective of this study was to evaluate the efficacy, safety, and duration of action of viscosupplementation with Crespine® Gel over a 9-month period. Materials and methods The study was a post-marketing Phase IV study. A total of 109 participants with osteoarthritis of the knee (grades 1–4) in the tibio–femoral compartment were recruited in Jordan. Data were collected from each participant during the baseline visit. Each participant received Crespine® Gel injection, and follow-up visits took place at 3 months, 6 months, and 9 months post-injection. Main outcome measure(s) An assessment of participants by phone was conducted at 1 month, 2 months, 4 months, 5 months, 7 months, and 8 months post-injection. Western Ontario and McMaster Universities Arthritis Index questionnaires were completed during each visit. A 72-hour visit questionnaire was used to assess the safety of the injection. Statistical analysis included a two-sided 95% confidence interval for the difference between pain scores across visits, and the percent change from baseline was calculated. Main results The full analysis included 84 participants who gave their informed consent and finished the necessary baseline and follow-up visits needed to assess efficacy and safety. Peak improvement was noted at 5 months post-injection, when pain and physical performance scores had decreased to 2.60 and 9.90, respectively, and the stiffness score was 0.33. The peak improvement in stiffness was noted at 8 months post-injection, when the stiffness score had decreased to 0.32. Significant improvements were still apparent at 9 months post-injection, when the pain score was 3.36, the stiffness score was 0.42, and the physical performance score was 11.5. All side effects were local and transient, and included pain, swelling, and redness of the knee. Most side effects were treated. Conclusion Hyaluronan should be encouraged as an alternative or adjunct treatment to oral analgesics to reduce their required doses, and delay potential future surgical intervention. PMID:25897212

The Human Side of Information's Converging Technology.

ERIC Educational Resources Information Center

Williams, Berney

1982-01-01

Discusses current issues in the design of information systems, noting contributions from three professions--computer science, human factors engineering, and information science. The eclectic nature of human factors engineering and the difficulty of drawing together studies with human engineering or software psychological components from diverse…

14. Photocopy of photograph (source unknown) photographer unknown pre1885 NORTH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. Photocopy of photograph (source unknown) photographer unknown pre-1885 NORTH SIDE AND WEST FRONT (NOTE ABSENCE OF DORMER ON GAMBREL ROOF OF ELL) (Illustration #6 of Data Report included in Field Records) - Narbonne House, 71 Essex Street, Salem, Essex County, MA

Genetics of Parenting: The Power of the Dark Side

ERIC Educational Resources Information Center

Oliver, Bonamy R.; Trzaskowski, Maciej; Plomin, Robert

2014-01-01

Reviews of behavioral genetic studies note that "control" aspects of parenting yield low estimates of heritability, while "affective" aspects (parental feelings) yield moderate estimates. Research to date has not specifically considered whether positive and negative aspects of parenting--for both feelings and control--may…

49 CFR 571.120 - Tire selection and rims and motor home/recreation vehicle trailer load carrying capacity...

Code of Federal Regulations, 2010 CFR

2010-10-01

... industry or manufacturer's designation for a rim by style or code. Weather side means the surface area of... CFR 1.50) [42 FR 7144, Feb. 7, 1977] Editorial Note: For Federal Register citations affecting § 571...

View of approach span and movable span, looking southeast from ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View of approach span and movable span, looking southeast from navy land. Note that navigational channel exists only on north side of movable span. - Naval Supply Annex Stockton, Daggett Road Bridge, Daggett Road traversing Burns Cut Off, Stockton, San Joaquin County, CA

Bilateral juvenile nasopharyngeal angiofibroma: report of a case.

PubMed

Wu, Edward C; Chark, Davin W; Bhandarkar, Naveen D

2014-07-01

Juvenile nasopharyngeal angiofibroma (JNA) is the most common benign neoplasm of the nasopharynx. Almost always unilateral on diagnosis, JNAs are locally invasive and may extend across the midline, giving a false bilateral appearance; as such, true bilateral JNA is exceedingly rare. We present a recent case of true bilateral JNA. Single case report of a patient with bilateral JNA, including clinical presentation, diagnosis, and management. The patient presented with unilateral nasal obstruction and recurrent epistaxis. Computed tomography and magnetic resonance imaging demonstrated bilateral, noncontiguous masses. Angiography revealed independent vascular supplies from each respective side with no bilateral supply noted. The patient underwent preoperative embolization followed by endoscopic surgical removal of the larger mass; no complications were noted. Follow-up at 2 years demonstrated no recurrence or growth. The vast majority of JNAs are unilateral, though invasive growth to the contralateral side may appear "bilateral" in presentation. Proper identification of true bilateral JNA is helpful in guiding management, wherein excision of both tumors may not be necessary. © 2014 ARS-AAOA, LLC.

Beneficial Effects of Palmitoylethanolamide on Expressive Language, Cognition, and Behaviors in Autism: A Report of Two Cases.

PubMed

Antonucci, Nicola; Cirillo, Alessandra; Siniscalco, Dario

2015-01-01

Introduction. Autism spectrum disorders are defined by behavioral and language atypias. Growing body of evidence indicates inflammatory mediators may contribute to the condition. Palmitoylethanolamide (PEA) is naturally occurring and has been available as a nonprescription medical food supplement in Europe since 2008. PEA has been tested in thousands of human subjects without any noted significant side effects. Here we report the first cases of the administration of PEA to two children with autism. Case Presentations. The first 13-year-old male child (Subject 1) presented with a total IgE of 572 IU/mL (nl < 200) and with low mature CD57(+) natural killer cell counts (32 cells/µL; nl = 60-300 cells/µL) and with significant eczema and allergic stigmata. Expressive language, as measured by mean length of utterance, and overall autism severity as measured by the Childhood Autism Rating Scale, Second Edition, improved significantly. Atopic symptoms diminished. No side effects were reported. The second male child, age 15 (Subject 2), also displayed noticeable and rapid improvements in cognitive, behaviors, and sociability. Conclusion. Currently, there is no definitive treatment for autism condition. Palmitoylethanolamide could be an effective treatment for autism syndrome. We propose appropriate double-blind clinical trials to further explore palmitoylethanolamide efficacy and safety.

MX Siting Investigation. Water Resources Program, Technical Summary Report. Volume IIA.

DTIC Science & Technology

1981-11-30

Block 20. it dilfe.ent from Report) L (.TN IS. SUPPLEMENTARY NOTES 19. KEY WORDS (Continue on reserse side It necessary amd Identify by block number...Sv .,zt 2*O:LI-y lo’.L1 _ XI e A.I p .*.",//. / /V_ , 20. ABSTRACT (Conitnuo on reverese side It necessary end idenLiy by b)ock number...51-II A-I WELL AND SPRING NUMBERING SYSTEM-NEVADA The numbering system for wells and springs in this report is based on the rectangular subdivision of

PROCESS WATER BUILDING, TRA605. AERIAL TAKEN WHILE SEVERAL PIPE TRENCHES ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PROCESS WATER BUILDING, TRA-605. AERIAL TAKEN WHILE SEVERAL PIPE TRENCHES REMAINED OPEN. CAMERA FACES EASTERLY. NOTE DUAL PIPES BETWEEN REACTOR BUILDING AND NORTH SIDE OF PROCESS WATER BUILDING. PIPING NEAR WORKING RESERVOIR HEADS FOR RETENTION RESERVOIR. PIPE FROM DEMINERALIZER ENTERS MTR FROM NORTH. SEE ALSO TRENCH FOR COOLANT AIR DUCT AT SOUTH SIDE OF MTR AND LEADING TO FAN HOUSE AND STACK. INL NEGATIVE NO. 2966-A. Unknown Photographer, 7/31/1951 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

Note: Modification of the Gay-Berne potential for improved accuracy and speed

NASA Astrophysics Data System (ADS)

Persson, Rasmus A. X.

2012-06-01

A modification of the Gay-Berne (GB) potential is proposed which is about 10% to 20% more speed efficient and statistically more accurate in reproducing the energy of interaction of two linear Lennard-Jones tetratomics when averaged over all orientations. For the special cases of end-to-end and side-by-side configurations, the new potential is equivalent to the GB one. A simple generalization to dissimilar particles of D∞h symmetry is presented but does not retain the superior agreement with respect to its GB counterpart, except at close range.

Detail view of the aft section, port side, of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view of the aft section, port side, of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the removed Orbiter Maneuvering System/Reaction Control System pod from the base of the vertical stabilizer the strongback ground-support equipment attached to the payload bay door. This view is also a good view of the leading edge and top surface of the Orbiter wing. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

PBF Reactor Building (PER620) under construction. Aerial view with camera ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PBF Reactor Building (PER-620) under construction. Aerial view with camera facing northeast. Steel framework is exposed for west wing and high bay. Concrete block siding on east wing. Railroad crane set up on west side. Note trenches proceeding from front of building. Left trench is for secondary coolant and will lead to Cooling Tower. Shorter trench will contain cables leading to control area. Photographer: Larry Page. Date: March 22, 1967. INEEL negative no. 67-5025 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

High-precision numerical integration of equations in dynamics

NASA Astrophysics Data System (ADS)

Alesova, I. M.; Babadzanjanz, L. K.; Pototskaya, I. Yu.; Pupysheva, Yu. Yu.; Saakyan, A. T.

2018-05-01

An important requirement for the process of solving differential equations in Dynamics, such as the equations of the motion of celestial bodies and, in particular, the motion of cosmic robotic systems is high accuracy at large time intervals. One of effective tools for obtaining such solutions is the Taylor series method. In this connection, we note that it is very advantageous to reduce the given equations of Dynamics to systems with polynomial (in unknowns) right-hand sides. This allows us to obtain effective algorithms for finding the Taylor coefficients, a priori error estimates at each step of integration, and an optimal choice of the order of the approximation used. In the paper, these questions are discussed and appropriate algorithms are considered.

Insight into the da Vinci® Xi - technical notes for single-docking left-sided colorectal procedures.

PubMed

Ngu, James Chi-Yong; Sim, Sarah; Yusof, Sulaiman; Ng, Chee-Yung; Wong, Andrew Siang-Yih

2017-12-01

The adoption of robot-assisted laparoscopic colorectal surgery has been hampered by issues with docking, operative duration, technical difficulties in multi-quadrant access, and cost. The da Vinci® Xi has been designed to overcome some of these limitations. We describe our experience with the system and offer technical insights to its application in left-sided colorectal procedures. Our initial series of left-sided robotic colorectal procedures was evaluated. Patient demographics and operative outcomes were recorded prospectively using a predefined database. Between March 2015 and April 2016, 54 cases of robot-assisted laparoscopic left-sided colorectal procedures were successfully completed with no cases of conversion. The majority were low anterior resections for colorectal malignancies. Using the da Vinci® Xi Surgical System, multi-quadrant surgery involving dissection from the splenic flexure to the pelvis was possible without redocking. The da Vinci® Xi simplifies the docking procedure and makes single-docking feasible for multi-quadrant left-sided colorectal procedures. Copyright © 2016 John Wiley & Sons, Ltd.

Continuous Lidocaine Infusions to Manage Opioid-Refractory Pain in a Series of Cancer Patients in a Pediatric Hospital.

PubMed

Gibbons, Kathleen; DeMonbrun, Andrea; Beckman, Elizabeth J; Keefer, Patricia; Wagner, Deb; Stewart, Margaret; Saul, D'Anna; Hakel, Stephanie; Liu, My; Niedner, Matthew

2016-07-01

Research on the safety and efficacy of continuous lidocaine infusions (CLIs) for the treatment of pain in the pediatric setting is limited. This article describes a series of pediatric oncology patients who received lidocaine infusions for refractory, longstanding, cancer-related pain. This is a retrospective review of patients who underwent lidocaine infusions to manage severe, opioid-refractory, cancer-related pain. Four patients ranging in age from 8 to 18 years were admitted to a pediatric hospital for their medical conditions and/or pain management. Structured chart review established demographic and diagnosis information, infusion rates, side effects, and efficacy of infusions in providing pain relief. Lidocaine bolus doses, infusion rates, serum concentrations, and subjective pain scores were analyzed. Median pain scores prior to lidocaine infusions were 8/10, falling to 2/10 at the infusion termination (P < 0.003), and rising to 3/10 in the first 24 hr after lidocaine (P < 0.029 compared to preinfusion pain). The infusions were generally well tolerated, with few side effects noted. In most cases, the improvement in pain scores persisted beyond termination of the infusion. CLIs were a helpful adjuvant in the four cases presented and may be an effective therapy for a more diverse array of refractory cancer pain. The majority of patients experienced pain relief well beyond the metabolic elimination of the lidocaine, corroborating a modulation effect on pain windup. Additional research regarding infusion rates, serum concentrations, side effects, and outpatient follow-up in a larger group of patients will provide additional insight into the role and safety of this therapy in children. © 2016 Wiley Periodicals, Inc.

Saturn's satellites - Near-infrared spectrophotometry (0.65-2.5 microns) of the leading and trailing sides and compositional implications

NASA Technical Reports Server (NTRS)

Steele, A.; Clark, R. N.; Brown, R. H.; Owensby, P. D.

1984-01-01

Water ice absorptions at 2.0, 1.5, and 1.25 microns are noted in near-IR spectra of Tethys, Dione, Rhea, Iapetus, and Hyperion, and the weak 1.04-micron ice absorption, which is detected for Rhea and Dione, is studied to establish band depth upper limits. The leading-trailing side 1.04-micron ice band depth differences on Saturn's satellites are similar to those for the Galilean satellites, indicating possible surface modification by magnetospheric charged particle bombardment. Limits are obtained for the amounts of particulates, trapped gases, and ammonium hydroxide on the surface. With the exception of the dark side of Iapetus, the surfaces of all of Saturn's satellites are nearly pure ice water.

Energy efficiency, human behavior, and economic growth: Challenges to cutting energy demand to sustainable levels

NASA Astrophysics Data System (ADS)

Santarius, Tilman

2015-03-01

Increasing energy efficiency in households, transportation, industries, and services is an important strategy to reduce energy service demand to levels that allow the steep reduction of greenhouse gases, and a full fledged switch of energy systems to a renewable basis. Yet, technological efficiency improvements may generate so-called rebound effects, which may `eat up' parts of the technical savings potential. This article provides a comprehensive review of existing research on these effects, raises critiques, and points out open questions. It introduces micro-economic rebound effect and suggests extending consumer-side analysis to incorporate potential `psychological rebound effects.' It then discusses meso-economic rebound effects, i.e. producer-side and market-level rebounds, which so far have achieved little attention in the literature. Finally, the article critically reviews evidence for macro-economic rebound effects as energy efficiency-induced economic growth impacts. For all three categories, the article summarizes assessments of their potential quantitative scope, while pointing out remaining methodological weaknesses and open questions. As a rough "rule of thumb", in the long term and on gross average, only half the technical savings potential of across-the-board efficiency improvements may actually be achieved in the real world. Policies that aim at cutting energy service demand to sustainable levels are well advised to take due note of detrimental behavioral and economic growth impacts, and should foster policies and measures that can contain them.

3. Photocopy of July 13, 1959 photograph, courtesy of Committee ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Photocopy of July 13, 1959 photograph, courtesy of Committee of Public Property, Philadelphia, Pennsylvania. VIEW OF UNDERGROUND VAULT WITH GRANITE CEILING AND RUBBLE WALL. NOTE ARCH AT RIGHT SIDE OF PHOTO - Granite Street Vaults, 100-112 & 101-127 Granite Street, Philadelphia, Philadelphia County, PA

36. BOILER HOUSE, GENERAL VIEW LOOKING TOWARD COAL CAR No. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

36. BOILER HOUSE, GENERAL VIEW LOOKING TOWARD COAL CAR No. 6 (NOTE: COAL DISTRIBUTER HOPPER & CONVEYOR THAT RUNS NORTH TO SOUTH BETWEEN TRACKS ON EAST TOWER SIDE) - Delaware County Electric Company, Chester Station, Delaware River at South end of Ward Street, Chester, Delaware County, PA

Hangar no. 1 perspective view of south doors and west ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Hangar no. 1 perspective view of south doors and west side doors. Seen from hangar apron. Note hydrogen building at left edge distance. Looking 44 NE. - Marine Corps Air Station Tustin, Northern Lighter Than Air Ship Hangar, Meffett Avenue & Maxfield Street, Tustin, Orange County, CA

4. EXTERIOR OF SOUTH END OF BUILDING 108 SHOWING STORM ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. EXTERIOR OF SOUTH END OF BUILDING 108 SHOWING STORM PORCH ADDITION AND WINDOWS ALONG BACK (WEST SIDE) OF HOUSE. NOTE ORIGNAL SHORT CHIMNEY AT CREST OF ROOF. VIEW TO NORTH. - Rush Creek Hydroelectric System, Clubhouse Cottage, Rush Creek, June Lake, Mono County, CA

47. VIEW ON THE ROOF, LOOKING EAST TO WEST FROM ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

47. VIEW ON THE ROOF, LOOKING EAST TO WEST FROM THE SOUTHWEST CORNER OF THE MAIN ROOF (NOTE CHIMNEY TO NORTH & PEAK OF METAL ROOF COVERING THE EAST SIDE BAY OF OCTAGONAL ROOMS) - Kenworthy Hall, State Highway 14 (Greensboro Road), Marion, Perry County, AL

3. BUNKER HILL LEAD SMELTER. VIEW IS FROM CIA TO ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. BUNKER HILL LEAD SMELTER. VIEW IS FROM CIA TO THE SOUTHWEST. BUILDINGS NOTED IN ID-29-2 APPEAR, IN ADDITION TO DRY ORE PLANT AND BONNOT COAL PULVERIZING EQUIPMENT BUILDING ON THE RIGHT. - Bunker Hill Lead Smelter, Bradley Rail Siding, Kellogg, Shoshone County, ID

70. GENERAL VIEW OF CANAL IN DOVER LOOKING EAST. WHAT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

70. GENERAL VIEW OF CANAL IN DOVER LOOKING EAST. WHAT APPEARS TO BE A SWING BRIDGE IS VISIBLE ACROSS CANAL ON RIGHT SIDE OF PHOTOGRAPH (NOTE THAT THIS MAY ALSO BE A LIFT BRIDGE WITH THE LIFT EQUIPMENT REMOVED). - Morris Canal, Phillipsburg, Warren County, NJ

Treatment of AA amyloidosis in rheumatoid arthritis.

PubMed

Balakrishnan, C; Sule, A; Mittal, G; Gaitonde, S; Pathan, E; Rajadhyaksha, S; Deshpande, R B; Gurmeet, M; Samant, R; Joshi, V R

2002-07-01

Four patients of rheumatoid arthritis (RA) with biopsy confirmed AA amyloidosis were treated with chlorambucil. All had established but uncontrolled RA with a persistently raised ESR. Moderate (> 1 gm, < 3.5 gm/d) to nephrotic range (> 3.5 gm/d) proteinuria and a relatively well preserved renal function was noted in three patients. One patient had deranged renal function and required dialysis. On chlorambucil, there was complete recovery, partial improvement and no improvement in one patient each. The fourth patient required haemodialysis, did not tolerate chlorambucil and succumbed to the illness. Therapy with chlorambucil can benefit some patients of RA with AA amyloidosis. Leucopenia is the most important dose limiting side effect.

Ketoconazole in paracoccidioidomycosis: efficacy of prolonged oral therapy.

PubMed

Restrepo, A; Stevens, D A; Leiderman, E; Fuentes, J; Arana, A; Angel, R; Mejía, G; Gómez, I

1980-08-29

Ketoconazole, a new oral imidazole derivative, was employed for the treatment of five patients with paracoccidioidomycosis. The response was excellent, with objective clinical improvement and healing of both mucocutaneous and pulmonary lesions. Mycological and serological tests, as well as delayed hypersensitivity, were assessed and found to correlate with clinical improvement. Therapy was conducted for 12 months with a dose of 200 mg day in 2 patients; in the remainder the dose was reduced (100 mg day) after the first 6 months and maintained as such for an equal period. No side-effects or toxicity were noted despite prolonged treatment. The advantages of the new therapeutic approach are discussed.

[The use of deoxycholic acid (ATX-101) in aesthetic medicine: A promising treatment].

PubMed

Hersant, B; Calmon, A; Meningaud, J P

2015-12-01

ATX-101 is a synthetic derivative from deoxycholic acid, which leads to destruction of adipocytes and to a skin retraction. The US Food and Drug Administration (FDA) has authorized ATX-101 injections for reduction of moderate to severe submental fat. The purpose of this note is to review the data of literature regarding the deoxycholic acid (ATX-101) where a significant difference for the submental fat between the treated group and the placebo group according to clinical and morphological criteria was observed (Refine Study 1 and 2). Side effects of this molecule seems to be limited. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

The CAL: cognitive, apperceptive and representative aspects of fashion design - Side note to neuroaesthetic theory

NASA Astrophysics Data System (ADS)

Csanák, Edit

2017-10-01

This article deals with the creative and cognitive process of the creative work from the aspect of fashion design. It is examined through the Cognitive-Apperceptive-Limn process (The CAL), analysing the stages of design work referring to prominent literature, and discussing exciting theories, such the FLOW and the AHA effects are, and the neuro aesthetic theory. Setting them into a new context, the article offers a fresh approach of a designer, rather than a scientific statement based on pragmatic findings. Since theories on artistic performance and creativity can never be enough ‘empirical’, and the process can be never understood enough well…

A Novel Approach towards Medical Entity Recognition in Chinese Clinical Text

PubMed Central

Yu, Jian

2017-01-01

Medical entity recognition, a basic task in the language processing of clinical data, has been extensively studied in analyzing admission notes in alphabetic languages such as English. However, much less work has been done on nonstructural texts that are written in Chinese, or in the setting of differentiation of Chinese drug names between traditional Chinese medicine and Western medicine. Here, we propose a novel cascade-type Chinese medication entity recognition approach that aims at integrating the sentence category classifier from a support vector machine and the conditional random field-based medication entity recognition. We hypothesized that this approach could avoid the side effects of abundant negative samples and improve the performance of the named entity recognition from admission notes written in Chinese. Therefore, we applied this approach to a test set of 324 Chinese-written admission notes with manual annotation by medical experts. Our data demonstrated that this approach had a score of 94.2% in precision, 92.8% in recall, and 93.5% in F-measure for the recognition of traditional Chinese medicine drug names and 91.2% in precision, 92.6% in recall, and 91.7% F-measure for the recognition of Western medicine drug names. The differences in F-measure were significant compared with those in the baseline systems. PMID:29065612

Alternative Packaging for Back-Illuminated Imagers

NASA Technical Reports Server (NTRS)

Pain, Bedabrata

2009-01-01

An alternative scheme has been conceived for packaging of silicon-based back-illuminated, back-side-thinned complementary metal oxide/semiconductor (CMOS) and charge-coupled-device image-detector integrated circuits, including an associated fabrication process. This scheme and process are complementary to those described in "Making a Back-Illuminated Imager With Back-Side Connections" (NPO-42839), NASA Tech Briefs, Vol. 32, No. 7 (July 2008), page 38. To avoid misunderstanding, it should be noted that in the terminology of imaging integrated circuits, "front side" or "back side" does not necessarily refer to the side that, during operation, faces toward or away from a source of light or other object to be imaged. Instead, "front side" signifies that side of a semiconductor substrate upon which the pixel pattern and the associated semiconductor devices and metal conductor lines are initially formed during fabrication, and "back side" signifies the opposite side. If the imager is of the type called "back-illuminated," then the back side is the one that faces an object to be imaged. Initially, a back-illuminated, back-side-thinned image-detector is fabricated with its back side bonded to a silicon handle wafer. At a subsequent stage of fabrication, the front side is bonded to a glass wafer (for mechanical support) and the silicon handle wafer is etched away to expose the back side. The frontside integrated circuitry includes metal input/output contact pads, which are rendered inaccessible by the bonding of the front side to the glass wafer. Hence, one of the main problems is to make the input/output contact pads accessible from the back side, which is ultimately to be the side accessible to the external world. The present combination of an alternative packaging scheme and associated fabrication process constitute a solution of the problem.

MTR WING, TRA604. ONE OF THE LABORATORY UNITS ALONG THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

MTR WING, TRA-604. ONE OF THE LABORATORY UNITS ALONG THE SOUTH SIDE WALL. NOTE SINK, CABINET, TABLE, AND HOOD UNITS. DUCT ABOVE RECEIVES CONTAMINATED AIR AND SENDS IT TO FAN HOUSE AND STACK. NOTE PARTITION WALL BEHIND WORK UNITS. THE HEALTH PHYSICS LAB WAS SIMILARLY EQUIPPED. WINDOW AT LEFT EDGE OF VIEW. CARD IN LOWER RIGHT WAS INSERTED BY INL PHOTOGRAPHER TO COVER AN OBSOLETE SECURITY RESTRICTION PRINTED ON ORIGINAL NEGATIVE. INL NEGATIVE NO. 4225. Unknown Photographer, 2/13/1952 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

102. Interior view of utilidor passageway link between building nos. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

102. Interior view of utilidor passageway link between building nos. 101 and 102 showing waveguides on left and cable tray system on right sides. Note fire suppression water supply piping (upper center). Small maintenance 3-wheel vehicle at center (Note: similar vehicles still in use in 2001.) Official photograph BMEWS Project by Hansen, Photographic Services, Riverton, NJ, BMEWS, clear as negative no. A-101123. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

A Note on Helga's Dilemma: The Dark Side of Kohlberg.

ERIC Educational Resources Information Center

Kirman, Joseph M.

1991-01-01

Argues that exposing children to some of Lawrence Kohlberg's moral dilemmas, such as Helga's dilemma, may be pedagogically unsound at the elementary-school level. States sample responses provided are inappropriate, rigid, and self-righteous. Provides 10 reasons why this dilemma and its designated responses are of questionable morality. Claims…

3. PERSPECTIVE VIEW OF OVERSEERS COTTAGE AT 110 CORINTH ROAD. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. PERSPECTIVE VIEW OF OVERSEERS COTTAGE AT 110 CORINTH ROAD. NOTE ORIGINAL WOOD SIDING, PORCH POSTS, AND STEPS. ORIGINALLY THIS HOUSE SAT ON BRICK PIERS WITH WOOD LATTICE BETWEEN. THE FOUNDATION HAS NOW BEEN INFILLED WITH BRICK. - 110 Corinth Road (House), 110 Corinth Road, Hogansville, Troup County, GA

When They Just Don't Listen. Refining Your Communication Skills.

ERIC Educational Resources Information Center

Ensman, Richard C. Jr.

1998-01-01

Presents strategies to turn one-sided conversations into meaningful dialogs. Suggests, if a conversation partner is not allowing equal time, trying the following techniques: repeat statement; keep going; match other person's voice; use rejoinder; ask harsh question; simulate anger; alter body position; wag finger; raise eyebrows; take notes; ask…

48. Interior view of the second floor, looking from the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

48. Interior view of the second floor, looking from the northeast to the southwest generally (note common rafter roof and collar beams as well as the ghosts of dormer windows in the west side - Kiskiack, Naval Mine Depot, State Route 238 vicinity, Yorktown, York County, VA

An Environmental Ethic for Parks and Recreation.

ERIC Educational Resources Information Center

McAvoy, Leo

1990-01-01

Suggests an environmental ethic for parks and recreation professionals who are often on the wrong side of the environmental controversy because they lack a professional ethic. This article provides a guide for implementing an environmental ethic, noting that philosophy of service must be grounded in ecological principles, not merchant values. (SM)

The sunny side of lime.

PubMed

Quaak, Marjolijn S W; Martens, Herm; Hassing, Robert-Jan; van Beek-Nieuwland, Yvonne; van Genderen, Perry J J

2012-01-01

A 26-year-old woman was affected with a maculopapular rash because of a jellyfish sting on her right leg while surfing in Indonesia. A locally-prepared liniment was applied on the affected skin. She presented with hyperpigmented linear tracks that she noted a few days later. © 2012 International Society of Travel Medicine.

A Note from the Other Side.

ERIC Educational Resources Information Center

Kaplan, Paul S.

This paper describes two types of teacher educators, discusses "in" and "out"phrases of educational jargon, and concludes with six proposals. The author criticizes teachers who teach six months in a ghetto school and then write a book about the terrible teaching of their colleagues; and he criticizes teacher educators in large…

The Unheroic Side of Leadership: Notes from the Swamp.

ERIC Educational Resources Information Center

Murphy, Jerome T.

1988-01-01

Administrators who "lionize" leadership miss important behind-the-scenes aspects of daily management. They depict the grand design without niggling problems and assume that leadership belongs exclusiveley to the heroic boss. Leaders often achieve best results by being skilled listeners, acting like followers, and depending on followers…

1995 Matched Anthropometric Database of U.S. Marine Corps Personnel: Summary Statistics

DTIC Science & Technology

1996-09-01

the maximum point ofquiet respiration. Note: Breast tissue and latissimus dorsi muscle tissue are NOT included in this measurement ifthey extend...form one side of the pelvic cavity. Latissimus Dorsi - a large muscle located on the lower back that extends from just above the waist to behind

33. INTERIOR VIEW, DINING ROOM LOCATED AT THE SOUTHEAST CORNER ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

33. INTERIOR VIEW, DINING ROOM LOCATED AT THE SOUTHEAST CORNER OF THE HOUSE ON THE FIRST FLOOR, LOOKING TO THE FIREPLACE IN THE EAST WALL (NOTE DOORWAY TO THE MUSIC ROOM ON THE LEFT (NORTH) SIDE OF THE PHOTOGRAPH) - Arlington Place, 331 Cotton Avenue, Southwest, Birmingham, Jefferson County, AL

7. Close view of the lower portion of vertical sign ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Close view of the lower portion of vertical sign with the letters "A-G-O" after removal from theatre (Note: the steel I-beam was inserted and sheet metal side panels taken off to facilitate removal from theatre - Chicago Theater, 175 North State Street, Chicago, Cook County, IL

The Other "Real World": Gentrification and the Social Construction of Place in Chicago.

ERIC Educational Resources Information Center

Perez, Gina M.

2002-01-01

Explores competing constructions and understandings of the gentrifying neighborhoods on Chicago's near northwest side, noting how Puerto Rican youth are implicated in these changes. Explores contradictory images of neighborhoods, residents' responses to these changes, and various linguistic attempts to refashion new ethno-racial designations in…

Adrenocorticotropic hormone analog use for podocytopathies.

PubMed

Filippone, Edward J; Dopson, Shirley J; Rivers, Denise M; Monk, Rebeca D; Udani, Suneel M; Jafari, Golriz; Huang, Solomon C; Melhem, Arafat; Assioun, Bassim; Schmitz, Paul G

2016-01-01

Adrenocorticotropic hormone is being increasingly studied for treatment of various glomerulopathies, most notably membranous nephropathy. Less data are available regarding its use in idiopathic nephrotic syndrome (INS) secondary to minimal change disease (MCD) or focal segmental glomerulosclerosis (FSGS). We report here our experience with H.P. Acthar(®) Gel (repository corticotropin injection) as first-line or subsequent therapy in patients with INS. Data were taken from three patients with MCD and ten patients with FSGS from around the US, who were treated with Acthar Gel as initial or subsequent therapy. Treatment was solely at the discretion of the primary nephrologist without a specific protocol. A complete response (CR) was defined as final urine protein-to-creatinine ratio <500 mg/g and a partial response (PR) as 50% decrease without rise of serum creatinine. Side effects and tolerability were noted. All three patients with MCD received Acthar Gel as second-line or later immunosuppressive (IS) therapy and all responded (one CR and two PRs). Two of the ten patients with FSGS received Acthar Gel as first-line IS therapy, while the other eight had failed multiple agents. Four of the ten patients with FSGS had responses, including two CRs and two PRs. The three patients with MCD tolerated therapy well without side effects. Five patients with FSGS tolerated therapy well, while five had various steroid-like side effects, resulting in therapy discontinuation in two patients. Acthar Gel is a viable alternative IS agent for treatment of INS in patients intolerant or resistant to conventional therapy. More data are needed to better define its appropriate place.

Adrenocorticotropic hormone analog use for podocytopathies

PubMed Central

Filippone, Edward J; Dopson, Shirley J; Rivers, Denise M; Monk, Rebeca D; Udani, Suneel M; Jafari, Golriz; Huang, Solomon C; Melhem, Arafat; Assioun, Bassim; Schmitz, Paul G

2016-01-01

Background Adrenocorticotropic hormone is being increasingly studied for treatment of various glomerulopathies, most notably membranous nephropathy. Less data are available regarding its use in idiopathic nephrotic syndrome (INS) secondary to minimal change disease (MCD) or focal segmental glomerulosclerosis (FSGS). We report here our experience with H.P. Acthar® Gel (repository corticotropin injection) as first-line or subsequent therapy in patients with INS. Methods Data were taken from three patients with MCD and ten patients with FSGS from around the US, who were treated with Acthar Gel as initial or subsequent therapy. Treatment was solely at the discretion of the primary nephrologist without a specific protocol. A complete response (CR) was defined as final urine protein-to-creatinine ratio <500 mg/g and a partial response (PR) as 50% decrease without rise of serum creatinine. Side effects and tolerability were noted. Results All three patients with MCD received Acthar Gel as second-line or later immunosuppressive (IS) therapy and all responded (one CR and two PRs). Two of the ten patients with FSGS received Acthar Gel as first-line IS therapy, while the other eight had failed multiple agents. Four of the ten patients with FSGS had responses, including two CRs and two PRs. The three patients with MCD tolerated therapy well without side effects. Five patients with FSGS tolerated therapy well, while five had various steroid-like side effects, resulting in therapy discontinuation in two patients. Conclusion Acthar Gel is a viable alternative IS agent for treatment of INS in patients intolerant or resistant to conventional therapy. More data are needed to better define its appropriate place. PMID:27418857

Long-term outcomes after adjunctive topical 5-flurouracil or mitomycin C for the treatment of surgically excised, localized ocular surface squamous neoplasia.

PubMed

Bahrami, Bobak; Greenwell, Timothy; Muecke, James S

2014-01-01

To report rates of recurrence and complications of localized ocular surface squamous neoplasia treated with 5-fluorouracil or mitomycin C as adjunctive treatment to surgical excision. Long-term follow up of two prospective, non-comparative interventional case series. One hundred fifty-three eyes with histologically confirmed localized, non-invasive ocular surface squamous neoplasia. 89 eyes were treated with adjuvant 5-fluorouracil and 64 eyes were treated with adjuvant mitomycin C. Following surgical excision±cryotherapy patients received topical 5-fluorouracil 1% four times daily for two weeks or topical mitomycin C 0.04% four times daily for two to three 1-week cycles. Ocular surface squamous neoplasia recurrence, complications of therapy and compliance. Median follow up was 33.6 (range 12-84) months and 57.9 (range 12-160) months in 5-fluorouracil and mitomycin C groups, respectively. There was one recurrence in the 5-fluorouracil group and no recurrences in the mitomycin C group. Side-effects occurred in 69% of 5-fluorouracil patients and 41% of mitomycin C patients. Five patients (6%) required intervention for treatment-related side-effects in the 5-fluorouracil group versus 11 (17%) in the mitomycin C group. No vision-threatening complications were noted. Long-term recurrence of localised ocular surface squamous neoplasia is rare when topical 5-fluorouracil or mitomycin C are used as adjunctive treatment to surgical excision. While side-effects are common, the majority are transient and rarely limit compliance. © 2013 Royal Australian and New Zealand College of Ophthalmologists.

Tap water iontophoresis in the treatment of pediatric hyperhidrosis.

PubMed

Dagash, Haitham; McCaffrey, Sinead; Mellor, Katie; Roycroft, Agnes; Helbling, Ingrid

2017-02-01

The treatment options for localized hyperhidrosis include antiperspirants, anticholinergics, iontophoresis, botulinum toxin and surgery. Tap water iontophoresis (TWI) involves immersing the affected area in tap water and passing a small electrical current through the area. Our aim was to assess the success of this therapy in a pediatric cohort. Retrospective case note review of all patients younger than 18years who underwent TWI between 2002 and 2015. Demographic data, number of treatment sessions, side effects and overall success were analyzed. Individuals undergo 7 treatments over 4weeks. A positive outcome was determined as an improvement in symptoms. Pre- and posttreatment hyperhidrosis disease severity scale (HDSS) was measured. Data are presented as mean (range). Statistical analysis was by paired t-test. A P value of <0.05 was regarded as significant. There were 43 patients (30 females) with a mean age of 15 (8-17) years. Palmar and/or plantar hyperhidrosis (PPH) was present in 39/43 (91%) patients. Axillary hyperhidrosis (AH) was present in 19/43 (44%) patients. All patients (with the exception of one) underwent 7 sessions (5-7). Side effects included paresthesia (88%), pruritus (26%), pain (26%), erythema (14%), dryness (12%) as well as vesicle formation and abrasions in one patient (2%). A positive outcome was found in 84% (36/43) of patients. There was a significant reduction in mean HDSS (pre 3.5 vs. post 2; P=0.0001). TWI is a safe and effective modality of treatment for both PPH and AH in the pediatric population, with minimal side effects. Pediatric surgeons should offer this treatment option before considering more invasive surgical procedures. IV: Retrospective study. Crown Copyright © 2017. Published by Elsevier Inc. All rights reserved.

Paragonimus heterotremus and other Paragonimus spp. in Thailand: pathogenesis, clinic and treatment.

PubMed

Vanijanonta, S; Bunnag, D; Harinasuta, T

1984-01-01

Six species of Paragonimus have been reported in Thailand: P. siamensis in cat, bandicoot and rat; P. bangkokensis in mongoose; P. harinasutai in cat and dog (experiment); P. macrochis in bandicoot and rat; P. westermani in tiger and P. heterotremus in cat, dog and man. It is interesting to note that in 1965 two immature P. heterotremus worms were recovered for the first time in man, namely in subcutaneous swellings in a boy; in 1981 nine mature P. heterotremus worms were expectorated after praziquantel treatment. P. heterotremus has been postulated to be the main cause of human paragonimiasis in Thailand. The clinical manifestation of paragonimiasis heterotremus is similar to paragonimiasis westermani. In the 1960's and 1970's bithionol was used to treat paragonimiasis, the cure rate was only 50-60%, and side effects including urticaria, rash, abdominal pain, nausea, vomiting, diarrhoea and dizziness were common. In the past 4 years, niclofolan and praziquantel (2-cyclohexyl-carbonyl-1,2,3,6,7,11b-hexahydro - 4H - pyrazino [2,1-a]isoquinolin-4-one, EMBAY 8440, Biltricide) have been used. A single dose of 2 mg/kg body weight of niclofolan yielded 100% cure rate. Praziquantel at dosages of 3 X 25 mg/kg body weight daily for one day and two days gave 80% and 100% cure rates, respectively. The eggs disappeared in 2-3 weeks with improvement of symptoms and signs, but radiologically lesions took a few months or more to clear, depending on size and severity. Side effects in the niclofolan group were higher; in the praziquantel group side effects were minimal and no toxic effects were detected.

Laser-assisted depigmentation for resistant vitiligo: a retrospective case series with long-term follow-up.

PubMed

Boukari, F; Lacour, J P; Ortonne, J P; Bahadoran, P; Passeron, T

2014-03-01

Blanching creams are used to depigment and to achieve uniform skin tone in widespread vitiligo. Length of the treatment and side-effects strongly limit their use in common practice. To assess the long-term efficacy and tolerance of Q-Switched (QS) lasers for depigmenting the remaining unaffected skin in vitiligo. Retrospective study of vitiligo patients treated with QS lasers in the Department of Dermatology of the University Hospital of Nice, France, from 2002 to 2011. Localizations and the percentage of body surface area of treated lesions, the total number of sessions and the possible relapses and side-effects, were analysed. Global satisfaction of the patients was evaluated on a visual analogical scale. Sixteen areas of normally pigmented skin were treated in six patients. The median number of sessions to achieve a complete depigmentation was 2 (1-6). The mean duration of follow-up was 36 months (19-120). One third of the patients had no relapse. A complete repigmentation was observed after 21 months in one patient; a 50% repigmentation was noted in one patient, 7 months after the end of the treatment. Two patients showed a minimal repigmentation (<25%), 18 months and 9 years after the first laser treatments. The repigmentations were effectively treated with a maintenance session. The mean total number of sessions performed during this period was 3 (1-20). Side-effects were limited to transient purpura and crusts. The satisfaction of the patients was excellent (mean 9/10). conclusions: QS lasers appear as an efficient and safe modality for depigmenting normal skin in vitiligo. © 2012 The Authors. Journal of the European Academy of Dermatology and Venereology © 2012 European Academy of Dermatology and Venereology.

Efficacy of various locally applied chemicals as contragestational agents in rats.

PubMed

Conner, E A; Blake, D A; Parmley, T H; Burnett, L S; King, T M

1976-05-01

Test agents were selected because of previous evidence of contragestationaal activity when administered systemically or because of known local effects which would be likely to cause endometrial changes having an adverse effect on pregnancy. A group of virgin female Sprague-Dawley rats were treated on Day 3 of pregnancy (preimplantation) and another group on Day 7 of pregnancy (postimplantation). Injections of .05 ml were made directly into the lumen of each uterine horn. Sodium chloride .9% was used on 1 side and the test agent on the other side. Implantation sites were counted before injections on Day 7. The number of corpora lutea indicated the expected number of conceptions of those injected on Day 3. On Day 15 rats were sacrificed and corpora lutea, viable conceptuses, and absorption sites were counted. Ethanol at 100, 80, 70, and 63% was a highly effective contragestational agent when given on Day 3. Formaldehyde 7-.5% was also highly effective when given on Day 3 but higher concentrations produced maternal toxicity and death. Silver nitrate, iodine, rivanol, cyclizine, urea, and 17beta-bromoacetoxy-19-nortestosterone produced no maternal toxicity but were all effective in reducing the number of viable fetuses. Prostaglandin (PGF2alpha), indomethacin, and ergonovine had no observable effect on preimplantation embryos. Methotrexate reduced survival when injected on Day 3 and more so when given on Day 7 but a systemic toxic effect was also noted. When injected on Day 7 all of the compounds except methotrexate were markedly less effective. Survival of fetuses in the control horns varied from 50% to 100%. Ethanol produced sloughing and necrosis but the endometrium appeared to be normal after 96 hours. Fecundity had not returned after 4-5 estrous cycles. The other compounds produced no histologically evident long-lasting effects. Superficial endometrial damage seemed to be the mechanism of action of compounds that were effective on Day 3. The discrepancies noted between results obtained and the documented efficiency of PGF2alpha and of urea as abortifacients in humans raises the question of the suitability of the rat as a model for predicting abortifacient activity in humans. However, the action of these 2 substances may be different in later gestational phases.

Detail view of the port side of the aft fuselage ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view of the port side of the aft fuselage of the Orbiter Discovery in the transfer aisle of the Vehicle Assembly Building at Kennedy Space Center with a lifting frame attached to the aft attach points of the orbiter. In this view, the Orbiter Maneuvering/Reaction Control Systems pod is in place. Also note the darker-colored trapezoidal aft fuselage access door and the T-0 umbilical panel to its right in the view. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

The correlation between movement of the center of mass and the kinematics of the spine, pelvis, and hip joints during body rotation.

PubMed

Wada, Osamu; Tateuchi, Hiroshige; Ichihashi, Noriaki

2014-01-01

Body rotation is associated with many activities. The concomitant movement of the center of mass (COM) is essential for effective body rotation. This movement is considered to be influenced by kinematic changes in the spine, pelvis, and hip joints. However, there is no research on the association between COM movement and kinematic changes during body rotation. We aimed to investigate the association between COM movement and the kinematics of the spine, pelvis, and hip joints during body rotation in standing. Twenty-four healthy men were included in the study. COM movement during active body rotation in a standing position was measured. We evaluated pelvic shift and changes in the angles of the spine, pelvis, and hip joints. We calculated the Pearson correlation coefficients to analyze the relationship between COM movement and kinematic changes in the spine, pelvis, and hip joints. There were significant correlations between lateral COM movement to the rotational side and pelvic shift to the rotational side, and between posterior COM movement and pelvic shift to the posterior side. In addition, lateral COM movement to the rotational side showed significant and negative correlation with spinal flexion and was significantly and positively correlated with the change in anterior pelvic tilt. Clinicians need to take particular note of both spinal and pelvic motion in the sagittal plane, as well as the pelvic shift, to speculate COM movement during body rotation in standing. Copyright © 2013 Elsevier B.V. All rights reserved.

[Effect of morphine on pain sensitivity after removal of the 1st and 2d somatosensory areas of the cerebral cortex in cats].

PubMed

Kukushkin, M L

1986-01-01

Behavioral experiments on adult cats were performed to study the development of morphine analgesia before and after ablation of the first (S1) and the second (S2) somatosensory cortex. It was shown that injection of morphine before ablation of the cortical areas leads to an equal increase of the nociceptive response thresholds on both sides of the body, predominantly at those levels of the conventional scale where the emotional affective component of pain is remarkable. It was also noted that after ablation of the S1 and S2 morphine exerts a different effect on changes in the nociceptive response thresholds. The role of the somatosensory cortical areas in an analysis of noxious signals is discussed.

Relation of serum molindone levels to serum prolactin levels and antipsychotic response.

PubMed

Pandurangi, A K; Narasimhachari, N; Blackard, W G; Landa, B S

1989-10-01

The antipsychotic drug molindone is considered to be atypical in its mode of action and to have mild side effects. Currently no data are available on the range of serum levels of this drug during treatment. By means of a high performance liquid chromatographic technique, serum molindone levels were measured in 14 psychotic patients receiving a wide range of doses of this drug. Molindone levels as high as 350 ng/mL were obtained and were not associated with any toxic effects. Significant relations were noted between the serum level of the drug and both serum prolactin level and treatment response. The authors suggest that molindone may have a range of serum levels consistent with therapeutic benefit. Serum molindone and prolactin levels might help assess resistance to molindone treatment.

Natural remedies for non-steroidal anti-inflammatory drug-induced toxicity.

PubMed

Simon, Jerine Peter; Evan Prince, Sabina

2017-01-01

The liver is an important organ of the body, which has a vital role in metabolic functions. The non-steroidal anti-inflammatory drug (NSAID), diclofenac causes hepato-renal toxicity and gastric ulcers. NSAIDs are noted to be an agent for the toxicity of body organs. This review has elaborated various scientific perspectives of the toxicity caused by diclofenac and its mechanistic action in affecting the vital organ. This review suggests natural products are better remedies than current clinical drugs against the toxicity caused by NSAIDs. Natural products are known for their minimal side effects, low cost and availability. On the other hand, synthetic drugs pose the danger of adverse effects if used frequently or over a long period. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

The Reappearance of Venus Observed 8 October 2015

NASA Astrophysics Data System (ADS)

Dunham, David W.; Dunham, Joan B.

2018-01-01

The reappearance of Venus on October 8, 2015 offered a unique opportunity to attempt observation of the ashen light of Venus as the unlit side of Venus emerged from behind the dark side of the Moon. The dark side of Venus would be offered to observers without interference from the bright side of Venus or of the Moon. Observations were made from Alice Springs, Australia visually with a 20-cm Schmidt-Cassegrain and with a low-light level surveillance camera on a 25-cm reflector. No evidence of the dark side was noted by the visual observer, the video shows little indication of Venus prior to the bright side reappearance. The conclusion reached is that the ashen light, as it was classically defined, is not observable visually or with small telescopes in the visual regime.The presentation describes the prediction, observation technique, and various analyses by the authors and others to draw conclusions from the data.To date, the authors have been unable to locate any reports of others attempting to observe this unique event. That is a pity since, not only was it interesting for an attempt to verify past observations of the ashen light, it was also a visually stunning event.

SPERTI Terminal Building (PER604). Oblique view of front entry and ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

SPERT-I Terminal Building (PER-604). Oblique view of front entry and one side. Electrical transformers at right of building. Note "Butler" logo. Photographer: R.G. Larsen. Date: June 22, 1955. INEEL negative no. 55-1700 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

Commander Brand stows trash in jettison bag on middeck

NASA Technical Reports Server (NTRS)

1982-01-01

Commander Brand disposes of empty food containers and dry trash in jettison bag and stows bag in middeck volume under MA73C control panel. Side hatch is visible behind Brand. Brand is wearing constant wear garment with communications kit assembly headset interface unit (HIU) and note pad strapped to his thighs.

Roadway into Facility 314 showing the roadway cut through the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Roadway into Facility 314 showing the roadway cut through the slope formed by leveling the area for the CDAA, note the concrete curb on the right side of the roadway, view facing west - U.S. Naval Base, Pearl Harbor, Naval Radio Station, AF/FRD-10 Circularly Disposed Antenna Array, Wahiawa, Honolulu County, HI

46. VIEW ON THE ROOF, LOOKING AT THE TOP (FOURTH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

46. VIEW ON THE ROOF, LOOKING AT THE TOP (FOURTH STORY) OF THE TOWER FROM THE NORTHEAST TO THE SOUTHWEST (NOTE: GROUPS OF THREE WINDOWS IN EACH SIDE OF TOWER, ORNAMENTED WITH BROWNSTONE ARCHES AND BROWNSTONE SILLS WITHOUT BRACKETS) - Kenworthy Hall, State Highway 14 (Greensboro Road), Marion, Perry County, AL

78 FR 13754 - Notice of Receipt of Petition for Decision That Nonconforming 2004 Ford F-150 Crew Cab Trucks...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-28

..., self-addressed postcard with the comments. Note that all comments received will be posted without... Components, 207 Seating Systems, 208 Occupant Crash Protection, 209 Seat Belt Assemblies, 210 Seat Belt Assembly Anchorages, 212 Windshield Mounting, 214 Side Impact Protection, 216 Roof Crush Resistance, 219...

10. INTERIOR OF ATTIC, VIEW FROM NORTH END LOOKING SOUTHEAST. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. INTERIOR OF ATTIC, VIEW FROM NORTH END LOOKING SOUTHEAST. NOTE ENTRANCE TO NORTH STAIR TOWER ON LEFT. THE HEAVY TIMBER TRUSS SYSTEM IS VISIBLE ALONG RIGHT SIDE OF PHOTOGRAPH. THIS SPACE WAS USED FOR PRODUCTION THROUGHOUT THE HISTORY OF THE MILL. - Graniteville Mill, Marshall Street, Graniteville, Aiken County, SC

An Honors Koan: Selling Water by the River

ERIC Educational Resources Information Center

Portnoy, Jeffrey A.

2013-01-01

Since Jerry Herron begins his forum essay, "Notes toward an Excellent Marxist-Elitist Honors Admissions Policy," with his anecdotal True Genealogical Confessions, Jeffery Portnoy, writes here that he feels feel obligated to begin in a similar mode. One side of Portnoy's family was in the real estate business in St. Louis, and the other…

45. CAPE COD AIR STATION PAVE PAWS FACILITY BUILDING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

45. CAPE COD AIR STATION PAVE PAWS FACILITY - BUILDING ELEVATION VIEW WITH BUILDING METAL SIDING BEING APPLIED ON "A" FACE (LEFT) AND "B" FACE (RIGHT). NOTE THAT NORTH IS GENERALLY TO RIGHT OF VIEW. - Cape Cod Air Station, Technical Facility-Scanner Building & Power Plant, Massachusetts Military Reservation, Sandwich, Barnstable County, MA

View of east elevation of Building No. 20. South Twentysixth ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View of east elevation of Building No. 20. South Twenty-sixth Street in middle ground. Seen from Building No. 21. Note boulders at left as landscape element. Looking west - Easter Hill Village, Building No. 20, West side of South Twenty-sixth Street, north of Hinkley Avenue, Richmond, Contra Costa County, CA

Families Get Involved! Learning Partners.

ERIC Educational Resources Information Center

Office of Educational Research and Improvement (ED), Washington, DC. Media and Information Services.

Noting that families who are involved in their children's education make a difference in their child's performance, this two-page information sheet encourages families to get involved by listing the benefits of family involvement on one side and the ways adult family members can help in the school on the other. As a result of family participation:…

85. INCLINED PLANE 7 EAST. FLUME AND STONE POWER HOUSE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

85. INCLINED PLANE 7 EAST. FLUME AND STONE POWER HOUSE ARE ON RIGHT SIDE OF PHOTOGRAPH. NOTE THE CABLE LEAVING THE POWER HOUSE. THIS CABLE IS ATTATCHED TO A DRUM ON THE INSIDE THE POWER HOUSE WHICH IS TURNED BY MEANS OF A WATER POWERED TURBINE. - Morris Canal, Phillipsburg, Warren County, NJ

Starkweather and Smith: Using "Contact Zones" to Teach Argument.

ERIC Educational Resources Information Center

Schutt, Robin Muksian

1998-01-01

Describes how a professor teaching a "Writing Arguments" course focused on two cases involving the death penalty to show students how arguments are constructed, and how students can form strong arguments of their own. Notes that this approach does not force students to choose sides when they stand somewhere in the middle. Describes four…

The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial.

PubMed

Gentile, Pietro; Garcovich, Simone; Bielli, Alessandra; Scioli, Maria Giovanna; Orlandi, Augusto; Cervelli, Valerio

2015-11-01

Platelet-rich plasma (PRP) has emerged as a new treatment modality in regenerative plastic surgery, and preliminary evidence suggests that it might have a beneficial role in hair regrowth. Here, we report the results of a randomized, evaluator-blinded, placebo-controlled, half-head group study to compare, with the aid of computerized trichograms, hair regrowth with PRP versus placebo. The safety and clinical efficacy of autologous PRP injections for pattern hair loss were investigated. PRP, prepared from a small volume of blood, was injected on half of the selected patients' scalps with pattern hair loss. The other half was treated with placebo. Three treatments were administered to each patient at 30-day intervals. The endpoints were hair regrowth, hair dystrophy as measured by dermoscopy, burning or itching sensation, and cell proliferation as measured by Ki67 evaluation. Patients were followed for 2 years. Of the 23 patients enrolled, 3 were excluded. At the end of the 3 treatment cycles, the patients presented clinical improvement in the mean number of hairs, with a mean increase of 33.6 hairs in the target area, and a mean increase in total hair density of 45.9 hairs per cm² compared with baseline values. No side effects were noted during treatment. Microscopic evaluation showed the increase of epidermis thickness and of the number of hair follicles 2 weeks after the last PRP treatment compared with baseline value (p < .05). We also observed an increase of Ki67(+) keratinocytes in the epidermis and of hair follicular bulge cells, and a slight increase of small blood vessels around hair follicles in the treated skin compared with baseline (p < .05). Relapse of androgenic alopecia was not evaluated in all patients until 12 months after the last treatment. After 12 months, 4 patients reported progressive hair loss; this was more evident 16 months after the last treatment. Those four patients were re-treated. Our data clearly highlight the positive effects of PRP injections on male pattern hair loss and absence of major side effects. PRP may serve as a safe and effective treatment option against hair loss; more extensive controlled studies are needed. Platelet-rich plasma (PRP) has emerged as a new treatment modality in regenerative plastic surgery, and preliminary evidence suggests that it might have a beneficial role in hair regrowth. Here, the results of a randomized, placebo-controlled, half-head group study to compare the hair regrowth with PRP versus placebo are reported. Hair regrowth was quantified by a blinded evaluator using computerized trichograms. The safety and clinical efficacy of autologous PRP injections for pattern hair loss were investigated. Of the 23 patients enrolled, 3 were excluded. At the end of the 3 treatment cycles, the patients presented clinical improvement in the mean number of hairs, with a mean increase of 33.6 hairs in the target area and a mean increase in total hair density of 45.9 hairs per cm² compared with baseline values. No side effects were noted during treatment. The data clearly highlight the positive effects of PRP injections on male pattern hair loss and absence of major side effects. PRP may serve as a safe and effective treatment option against hair loss; more extensive controlled studies are needed. ©AlphaMed Press.

The Clinical and Histological Effect of a Low-Fluence Q-Switched 1,064-nm Neodymium: Yttrium-Aluminum-Garnet Laser for the Treatment of Melasma and Solar Lentigenes in Asians: Prospective, Randomized, and Split-Face Comparative Study.

PubMed

Kaminaka, Chikako; Furukawa, Fukumi; Yamamoto, Yuki

2017-09-01

The low-fluence Q-switched 1,064-nm neodymium:yttrium-aluminum-garnet laser (QSNYL) is popular for melasma treatment among Asians. This study was to evaluate the clinical and histological effects of the low-fluence QSNYL for treatment of melasma and solar lentigenes. In this randomized split-face clinical study, 22 patients with melasma or solar lentigo received low-fluence QSNYL weekly for 10 sessions on one cheek. The treatment efficacy was determined by Mexameter skin colorimetry, physician and patient assessment, and by evaluating histological changes. The treated sides had statistically significant reductions in the melanin and erythema indices (EI); 50.0% of melasma and 62.5% of solar lentigo patients had >50% clearance after the final treatment. The increased EI, vascularity, and mast cell activity in patients with melasma and large-sized solar lentigo showed no improvement. The recurrence rates were 16.7% and 12.7% for melasma and solar lentigo, respectively. Postinflammatory hyperpigmentation developed in 1 patient, but no serious side effects were noted. Low-fluence QSNYL is effective in treating melasma and small type solar lentigo in Asians. The authors' study also demonstrated that lesion thickness, vascularity, and mast cell activity can be used to predict the efficacy of the treatment of these lesions.

Cephalometric assessment of human fetal head specimens.

PubMed

Radlanski, R J; Heikinheimo, K; Gruda, A

2013-07-01

Past investigations of prenatal craniofacial growth have largely relied on histological sections. Few studies have taken measurements on three-dimensional representations (3D reconstruction, 3D CT, postmortem) or varying depth levels (ultrasound), and we know of no craniofacial growth studies done on cleared-and-stained specimens of whole fetal heads. This study comprised 14 human fetal head specimens cleared and stained with alizarin red and alcian blue. They had been stored in glycerol and represented weeks 8-12 of gestation, with crown-rump lengths ranging from 23-145 mm. These specimens were cephalometrically analyzed in norma frontalis and norma lateralis, which notably included the opportunity for side-to-side comparison. As the cranial membrane bones progressively approached each other, the orbits, maxilla, and mandible gradually grew wider. Likewise, the sagittal dimensions of the maxilla and mandible increased continuously and synchronically. We noted side-to-side differences ranging from 2-5 mm. Another notable finding concerned the inclination of the maxilla relative to the cranial base, which increased more on the right than on the left side. This is the first investigation presenting side-to-side comparative measurements of human fetal head specimens. Such measurements are essential in the quest toward validating the findings of other imaging techniques such as CT or MRI and-most importantly-intrauterine sonography.

Augmentation of partially regenerated nerves by end-to-side side-to-side grafting neurotization: experience based on eight late obstetric brachial plexus cases

PubMed Central

2006-01-01

Objective The effect of end-to-side neurotization of partially regenerated recipient nerves on improving motor power in late obstetric brachial plexus lesions, so-called nerve augmentation, was investigated. Methods Eight cases aged 3 – 7 years were operated upon and followed up for 4 years (C5,6 rupture C7,8T1 avulsion: 5; C5,6,7,8 rupture T1 avulsion:1; C5,6,8T1 rupture C7 avulsion:1; C5,6,7 ruptureC8 T1 compression: one 3 year presentation after former neurotization at 3 months). Grade 1–3 muscles were neurotized. Grade0 muscles were neurotized, if the electromyogram showed scattered motor unit action potentials on voluntary contraction without interference pattern. Donor nerves included: the phrenic, accessory, descending and ascending loops of the ansa cervicalis, 3rd and 4th intercostals and contralateral C7. Results Superior proximal to distal regeneration was observed firstly. Differential regeneration of muscles supplied by the same nerve was observed secondly (superior supraspinatus to infraspinatus regeneration). Differential regeneration of antagonistic muscles was observed thirdly (superior biceps to triceps and pronator teres to supinator recovery). Differential regeneration of fibres within the same muscle was observed fourthly (superior anterior and middle to posterior deltoid regeneration). Differential regeneration of muscles having different preoperative motor powers was noted fifthly; improvement to Grade 3 or more occurred more in Grade2 than in Grade0 or Grade1 muscles. Improvements of cocontractions and of shoulder, forearm and wrist deformities were noted sixthly. The shoulder, elbow and hand scores improved in 4 cases. Limitations The sample size is small. Controls are necessary to rule out any natural improvement of the lesion. There is intra- and interobserver variability in testing muscle power and cocontractions. Conclusion Nerve augmentation improves cocontractions and muscle power in the biceps, pectoral muscles, supraspinatus, anterior and lateral deltoids, triceps and in Grade2 or more forearm muscles. As it is less expected to improve infraspinatus power, it should be associated with a humeral derotation osteotomy and tendon transfer. Function to non improving Grade 0 or 1 forearm muscles should be restored by muscle transplantation. Level of evidence Level IV, prospective case series. PMID:17147803

The diplomacy of scientific research in the South China Sea: the case of join to oceanographic marine scientific research expedition between Vietnam and the Philippines

NASA Astrophysics Data System (ADS)

Satyawan, I. A.

2018-03-01

The South China Sea is one of the hot-spot areas in the world. This area is claimed by China, Malaysia, Brunei, Taiwan, Vietnam and the Philippines. It also noted, the South China Sea is rich in biodiversity as well as oil and gas. On the other side, environmental degradation is still happening in the South China Sea due to the reluctance of surrounding states to conduct a preservation program and mitigating action on climate change effects. Joint Oceanographic Marine Scientific Research Expedition between Vietnam and the Philippines is a breakthrough to start collaboration actions as well as to conduct Science Diplomacy.

Exercise interventions for patients with pediatric cancer during inpatient acute care: A systematic review of literature.

PubMed

Rustler, Vanessa; Hagerty, Meaghan; Daeggelmann, Julia; Marjerrison, Stacey; Bloch, Wilhelm; Baumann, Freerk T

2017-11-01

Physical inactivity has been shown to exacerbate negative side effects experienced by pediatric patients undergoing cancer therapy. Exercise interventions are being created in response. This review summarizes current exercise intervention data in the inpatient pediatric oncology setting. Two independent reviewers collected literature from three databases, and analyzed data following the PRISMA statement for systematic reviews and meta-analyses. Ten studies were included, representing 204 patients. Good adherence, positive trends in health status, and no adverse events were noted. Common strategies included individual, supervised, combination training with adaptability to meet fluctuating patient abilities. We recommend that general physical activity programming be offered to pediatric oncology inpatients. © 2017 Wiley Periodicals, Inc.

Treatment of tumor-bearing dogs with actinomycin D.

PubMed

Hammer, A S; Couto, C G; Ayl, R D; Shank, K A

1994-01-01

Fifty dogs with advanced malignancies were treated with actinomycin D at doses ranging from 0.5 to 1.1 mg/m2 every 3 weeks. The greatest number of responses was noted in dogs with lymphoma, including dogs that had received prior chemotherapy. Other responding tumor types included anal sac adenocarcinoma, perianal adenocarcinoma, squamous cell carcinoma, thyroid carcinoma, and transitional cell carcinoma. The median time to maximum response for dogs with lymphoma was 7 days, with a median duration of 42 days. Gastrointestinal toxicity was the most frequently observed side effect. A dose of 0.6 to 0.7 mg/m2 appears to be appropriate for treating various malignancies in dogs.

Opiate Users' Perceived Barriers Against Attending Methadone Maintenance Therapy: A Qualitative Study in China

PubMed Central

Lin, Chunqing; Wu, Zunyou; Detels, Roger

2012-01-01

Methadone maintenance therapy (MMT) in China is facing challenges such as high relapse rates and low coverage. The study assessed factors influencing MMT utilization among opiate users. In-depth interviews were conducted among 30 opiate users in 2008 to ascertain the barriers against seeking MMT. Data were analyzed using ATLAS.ti. Barriers to the treatment included requirement of registration with police, perceived discrimination, logistic difficulties, side effects, fear of being addicted to another drug, lack of additional services, and economic burden. The result suggests the need for structural changes such as improving comprehensive services, simplifying application procedure, and enhancing referral system. The study's limitations are noted. PMID:21417558

Response to low dose indomethacin in two children with nephrogenic diabetes insipidus.

PubMed

Dayal, Devi; Verma Attri, Savita; Kumar Bhalla, Anil; Kumar, Rakesh

2015-01-01

Two children with nephrogenic diabetes insipidus (NDI) were treated with oral indomethacin (0.75-1.2 mg/kg/day) three times a day for a mean duration of 3 yrs. Remission occurred in both patients in terms of achieving a normal fluid balance and body growth and the drug was withdrawn in one patient after 2 yrs. The treatment was well tolerated and no side effects were noted. The mean duration of follow-up was 6.5 yrs. These long-term observations of a favourable response to low dose indomethacin in 2 children with NDI need to be tested on larger number of patients. © Polish Society for Pediatric Endocrinology and Diabetology.

Risk disparities in the globalisation of assisted reproductive technology: the case of Asia.

PubMed

Ha, Jung-Ok

2013-01-01

This paper analyses the disparities in risks associated with biomedical technology focusing on the results of assisted reproductive technology (ART). ART among biomedical technologies transferred to Asia is a representative case that reveals in its clinical use and related scientific research the global politics of technology. This study notes the global politics at work in the recognition of and reaction to such risks. While many Asian countries aggressively pursue technological development, weak legislative and administrative regulations have created various problems and controversial cases. This study asserts that risks associated with technology are characterised as social facts not natural ones or mere 'side effects', since technological development and risk are closely intertwined.

[A Review on the Use of Effect Size in Nursing Research].

PubMed

Kang, Hyuncheol; Yeon, Kyupil; Han, Sang Tae

2015-10-01

The purpose of this study was to introduce the main concepts of statistical testing and effect size and to provide researchers in nursing science with guidance on how to calculate the effect size for the statistical analysis methods mainly used in nursing. For t-test, analysis of variance, correlation analysis, regression analysis which are used frequently in nursing research, the generally accepted definitions of the effect size were explained. Some formulae for calculating the effect size are described with several examples in nursing research. Furthermore, the authors present the required minimum sample size for each example utilizing G*Power 3 software that is the most widely used program for calculating sample size. It is noted that statistical significance testing and effect size measurement serve different purposes, and the reliance on only one side may be misleading. Some practical guidelines are recommended for combining statistical significance testing and effect size measure in order to make more balanced decisions in quantitative analyses.

Energy efficiency, human behavior, and economic growth: Challenges to cutting energy demand to sustainable levels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Santarius, Tilman, E-mail: tilman@santarius.de

Increasing energy efficiency in households, transportation, industries, and services is an important strategy to reduce energy service demand to levels that allow the steep reduction of greenhouse gases, and a full fledged switch of energy systems to a renewable basis. Yet, technological efficiency improvements may generate so-called rebound effects, which may ‘eat up’ parts of the technical savings potential. This article provides a comprehensive review of existing research on these effects, raises critiques, and points out open questions. It introduces micro-economic rebound effect and suggests extending consumer-side analysis to incorporate potential ‘psychological rebound effects.’ It then discusses meso-economic rebound effects,more » i.e. producer-side and market-level rebounds, which so far have achieved little attention in the literature. Finally, the article critically reviews evidence for macro-economic rebound effects as energy efficiency-induced economic growth impacts. For all three categories, the article summarizes assessments of their potential quantitative scope, while pointing out remaining methodological weaknesses and open questions. As a rough “rule of thumb”, in the long term and on gross average, only half the technical savings potential of across-the-board efficiency improvements may actually be achieved in the real world. Policies that aim at cutting energy service demand to sustainable levels are well advised to take due note of detrimental behavioral and economic growth impacts, and should foster policies and measures that can contain them.« less

View of Earth photographed by Apollo 15 on voyage to the Moon

NASA Technical Reports Server (NTRS)

1971-01-01

This view of Earth was photographed by the Apollo 15 crewmen as they sped toward the fourth lunar landing. The spacecraft was between 25,000 and 30,000 nautical miles from Earth when this photo was made. The United States (note Florida), Central America and part of Canada can be seen at the left side of the picture, with South America at lower center. Spain and the northwest part of Africa can be seen at right. The Bahama Banks, unique geological feature, can be seen (different shade of blue) east of Florida. Also note large North Atlantic storm front moving over Greenland in upper center.

Prevention of temporal alopecia following rhytidectomy: the prophylactic use of minoxidil. A study of 60 patients.

PubMed

Eremia, Sorin; Umar, Sanusi H; Li, Cindy Y

2002-01-01

Temporal hair loss that results from traumatized hair follicles following rhytidectomy is an unsightly complication that can distress both the patient and the operating surgeon. Topical minoxidil is a proven therapy for androgenic alopecia and female senile alopecia. It has also been found to be useful in preventing the hair loss that commonly follows hair transplantation. To analyze through a retrospective study the effect of topical minoxidil on the incidence of temporal hair loss following facelift procedures. To our knowledge this is the first study to investigate the role of minoxidil in preventing post-rhytidectomy temporal alopecia. The charts of 60 women with a mean age of 58 years who underwent primary cervicofacial rhytidectomy were studied. Either a standard SMAS/flap technique or pliation was done in all cases. Each patient received either 2% or 5% topical minoxidil for 2 weeks before surgery and for 4 weeks after surgery, with a 5-day break period beginning on the day of surgery. Patients were monitored for complications immediately postoperatively and in 3-6 months of follow-up. Almost 80% of the patients underwent SMAS/flap procedures. Transient temporal alopecia was noted in only one patient, 6 weeks after discontinuing minoxidil. This resolved within 4 weeks of its reintroduction. The only other complications noted included minor hematomas (3.3%), skin slough/infection (1.7%), minor transient and localized edema (8.3%), minor ecchymosis (1.7%), a unilateral neuropraxia of the buccal nerve lasting 3 months (1.7%), and a minor temporary unilateral skin depression (1.7%). Side effects of minoxidil were not observed. On comparing our findings to results of larger rhytidectomy series in which minoxidil was not used prophylactically, and our experience before using minoxidil, we conclude that minoxidil plays a role in effectively preventing the temporal hair loss that occurs following primary cervicofacial rhytidectomies. We also found that minoxidil did not negatively impact on the risk of hematoma formation, skin necrosis, edema, or ecchymosis. Side effects of minoxidil did not present a problem.

Study on mechanism of amplitude fluctuation of dual-frequency beat in microchip Nd:YAG laser

NASA Astrophysics Data System (ADS)

Chen, Hao; Tan, Yidong; Zhang, Shulian; Sun, Liqun

2017-01-01

In the laser heterodyne interferometry based on the microchip Nd:YAG dual-frequency laser, the amplitude of the beat note periodically fluctuates in time domain, which leads to the instability of the measurement. On the frequency spectrums of the two mono-frequency components of the laser and their beat note, several weak sideband signals are observed on both sides of the beat note. It is proved that the sideband frequencies are associated with the relaxation oscillation frequencies of the laser. The mechanism for the relaxation oscillations inducing the occurrence of the sideband signals is theoretically analyzed, and the quantitative relationship between the intensity ratio of the beat note to the sideband signal and the level of the amplitude fluctuation is simulated with the derived mathematical model. The results demonstrate that the periodical amplitude fluctuation of the beat note is actually induced by the relaxation oscillation. And the level of the amplitude fluctuation is lower than 10% when the intensity ratio is greater than 32 dB. These conclusions are beneficial to reduce the amplitude fluctuation of the microchip Nd:YAG dual-frequency laser and improve the stability of the heterodyne interferometry.

Psychoanalytic and musical ambiguity: the tritone in gee, officer krupke.

PubMed

Jaffee Nagel, Julie

2010-02-01

The poignant and timeless Broadway musical West Side Story is viewed from the standpoint of taking musical forms as psychoanalytic data. The musical configuration of notes called the tritone (or diabolus in musica) is taken as a sonic metaphor expressing ambiguity both in musical vocabulary and in mental life. The tritone, which historically and harmonically represents instability, is heard throughout the score and emphasizes the intrapsychic, interpersonal, and social dramas that unfold within and between the two gangs in West Side Story. Particular emphasis is given to the comic but exceedingly sober song Gee, Officer Krupke. Bernstein's sensitivity to the ambiguity and tension inherent in the tritone in West Side Story is conceptualized as an intersection of music theory and theories of mind; this perspective holds implications for clinical practice and transports psychoanalytic concepts from the couch to the Broadway stage and into the community to address the complexities of love, hate, aggression, prejudice, and violence. Ultimately, West Side Story cross-pollinates music and theater, as well as music and psychoanalytic concepts.

Cyproterone acetate in treatment of precocious puberty.

PubMed Central

Kauli, R; Pertzelan, A; Prager-Lewin, R; Grünebaum, M; Laron, Z

1976-01-01

Twenty-nine children (23 girls, 6 boys) with precocious puberty were treated with cyproterone acetate for various periods of time ranging from 6 months to 3 years 4 months. They received an oral dose ranging from 70-150 mg/m2 per day, or an intramuscular depot injection once a fortnight or once a month at a dose ranging from 107-230 mg/m2. Both forms of therapy were found to suppress the signs of sexual maturation, but the oral form proved to be superior. Only the younger patients with a bone age under 11 years showed a beneficial effect upon linear growth and bone maturation. No side effects were noted, but additional advantageous effects upon behaviour and sociability were. It is concluded that at present cyproterone acetate by mouth is the drug of choice in the treatment of precocious puberty. The treatment should be initiated as early as possible to attain maximum benefit. PMID:952553

Oral administration of non-absorbable delayed release 6-mercaptopurine is locally active in the gut, exerts a systemic immune effect and alleviates Crohn’s disease with low rate of side effects: results of double blind Phase II clinical trial

PubMed Central

Israeli, E; Goldin, E; Fishman, S; Konikoff, F; Lavy, A; Chowers, Y; Melzer, E; Lahat, A; Mahamid, M; Shirin, H; Nussinson, E; Segol, O; Ya’acov, A Ben; Shabbat, Y; Ilan, Y

2015-01-01

Therapy for Crohn’s disease (CD) with thiopurines is limited by systemic side effects. A novel formulation of fixed-dose, delayed-release 6-mercaptopurine (DR-6MP) was developed, with local effect on the gut immune system and minimal absorption. The aim of this study was to evaluate the safety and efficacy of DR-6MP in patients with moderately severe CD compared to systemically delivered 6-mercaptopurine (Purinethol). Seventy CD patients were enrolled into a 12-week, double-blind controlled trial. The primary end-point was the percentage of subjects with clinical remission [Crohn’s Disease Activity Index (CDAI) < 150] or clinical response (100-point CDAI reduction). Twenty-six (56·5%) and 13 (54·2%) subjects from the DR-6MP and Purinethol cohorts, respectively, completed the study. DR-6MP had similar efficacy to Purinethol following 12 weeks of treatment. However, the time to maximal clinical response was 8 weeks for DR-6MP versus 12 weeks for Purinethol. A higher proportion of patients on DR-6MP showed clinical remission at week 8. A greater improvement in Inflammatory Bowel Disease Questionnaire (IBDQ) score was noted in the DR-6MP group. DR-6MP led to a decrease of CD62+ expression on T cells, implying a reduction of lymphocyte adhesion to site of inflammation. DR-6MP was safer than Purinethol, with significantly fewer adverse events (AEs). There was no evidence of drug-induced leucopenia in the DR-6MP group; the proportion of subjects who developed hepatotoxicity was lower for the DR-6MP. Non-absorbable DR-6MP is safe and biologically active in the gut. It is clinically effective, exerting a systemic immune response with low systemic bioavailability and a low incidence of side effects. PMID:25846055

Oral administration of non-absorbable delayed release 6-mercaptopurine is locally active in the gut, exerts a systemic immune effect and alleviates Crohn's disease with low rate of side effects: results of double blind Phase II clinical trial.

PubMed

Israeli, E; Goldin, E; Fishman, S; Konikoff, F; Lavy, A; Chowers, Y; Melzer, E; Lahat, A; Mahamid, M; Shirin, H; Nussinson, E; Segol, O; Ya'acov, A Ben; Shabbat, Y; Ilan, Y

2015-08-01

Therapy for Crohn's disease (CD) with thiopurines is limited by systemic side effects. A novel formulation of fixed-dose, delayed-release 6-mercaptopurine (DR-6MP) was developed, with local effect on the gut immune system and minimal absorption. The aim of this study was to evaluate the safety and efficacy of DR-6MP in patients with moderately severe CD compared to systemically delivered 6-mercaptopurine (Purinethol). Seventy CD patients were enrolled into a 12-week, double-blind controlled trial. The primary end-point was the percentage of subjects with clinical remission [Crohn's Disease Activity Index (CDAI) < 150] or clinical response (100-point CDAI reduction). Twenty-six (56·5%) and 13 (54·2%) subjects from the DR-6MP and Purinethol cohorts, respectively, completed the study. DR-6MP had similar efficacy to Purinethol following 12 weeks of treatment. However, the time to maximal clinical response was 8 weeks for DR-6MP versus 12 weeks for Purinethol. A higher proportion of patients on DR-6MP showed clinical remission at week 8. A greater improvement in Inflammatory Bowel Disease Questionnaire (IBDQ) score was noted in the DR-6MP group. DR-6MP led to a decrease of CD62(+) expression on T cells, implying a reduction of lymphocyte adhesion to site of inflammation. DR-6MP was safer than Purinethol, with significantly fewer adverse events (AEs). There was no evidence of drug-induced leucopenia in the DR-6MP group; the proportion of subjects who developed hepatotoxicity was lower for the DR-6MP. Non-absorbable DR-6MP is safe and biologically active in the gut. It is clinically effective, exerting a systemic immune response with low systemic bioavailability and a low incidence of side effects. © 2015 British Society for Immunology.

Artificial dispersion via high-order homogenization: magnetoelectric coupling and magnetism from dielectric layers

PubMed Central

Liu, Yan; Guenneau, Sébastien; Gralak, Boris

2013-01-01

We investigate a high-order homogenization (HOH) algorithm for periodic multi-layered stacks. The mathematical tool of choice is a transfer matrix method. Expressions for effective permeability, permittivity and magnetoelectric coupling are explored by frequency power expansions. On the physical side, this HOH uncovers a magnetoelectric coupling effect (odd-order approximation) and artificial magnetism (even-order approximation) in moderate contrast photonic crystals. Comparing the effective parameters' expressions of a stack with three layers against that of a stack with two layers, we note that the magnetoelectric coupling effect vanishes while the artificial magnetism can still be achieved in a centre-symmetric periodic structure. Furthermore, we numerically check the effective parameters through the dispersion law and transmission property of a stack with two dielectric layers against that of an effective bianisotropic medium: they are in good agreement throughout the low-frequency (acoustic) band until the first stop band, where the analyticity of the logarithm function of the transfer matrix () breaks down. PMID:24101891

Spirulina and Pentoxyfilline – A Novel Approach for Treatment of Oral Submucous Fibrosis

PubMed Central

Mulk, Bhavana Sujana; Deshpande, Prasannasrinivas; Velpula, Nagalakshmi; Chappidi, Vani; Chintamaneni, Raja Lakshmi; Goyal, Stuti

2013-01-01

Background: Oral submucous fibrosis is a habit associated insidious precancerous condition of the oral cavity commonly found in Asian countries. Many treatment modalities have been attempted in treating the condition apart from steroids which have been the main stay. Hence the present study was designed to assess the efficacy of spirulina and pentoxyfilline and also to compare them in oral submucous fibrosis. Material and Methods: Fourty Patients with clinico-histological diagnosis of oral sub mucous fibrosis were selected and divided into two groups with 20 in each group by simple randomization method. Group I received Pentoxyfilline and Group II Spirulina for period of 3 months. The efficacy was assessed by parameters like mouth opening, burning sensation and tongue protrusion using vernier caliper, visual analog scale and a metric scale respectively along with the side effects. Results: Student’s t-test was applied to obtain the results. Both Pentoxyfilline and Spirulina groups showed statistically significant results (p=0.000) in all the three parameters namely mouth opening, burning sensation and tongue protrusion. On comparing both the drugs statistically insignificant results were obtained for mouth opening (p=0.35) and tongue protrusion (p=0.25) but statistically significant difference was seen in subjective parameter i.e burning sensation (p=0.04). Side effects like bloating of stomach, nausea and gastritis were noted in the pentoxyfilline group in contrast to Spirulina group. Conclusion: Newer drugs Pentoxyfilline and Spirulina showed promising results in treatment of Oral sub mucous fibrosis. Spirulina was used for the first time for treatment of Oral submucous fibrosis (OSMF) and it proved to be superior than pentoxyfilline as no side effects were observed. Also it was superior in reducing burning sensation and hence can be advised in OSMF patients suffering from severe subjective symptoms. PMID:24551724

Surgical Outcome in Patients Taking Concomitant or Recent Intake of Oral Isotretinoin: A Multicentric Study-ISO-AIMS Study.

PubMed

Mahadevappa, Omprakash Heggadahalli; Mysore, Venkataram; Viswanath, Vishalakshi; Thurakkal, Salim; Majid, Imran; Talwar, Suresh; Aurangabadkar, Sanjeev J; Chatterjee, Manas; Bhat, M Ramesh; Barua, Shyamanta; Ganjoo, Anil

2016-01-01

The current standard recommendation is to avoid surgical interventions in patients taking oral isotretinoin. However, this recommendation has been questioned in several recent publications. To document the safety of cosmetic and surgical interventions, among patients receiving or recently received oral isotretinoin. Association of Cutaneous Surgeons, India, in May 2012, initiated this study, at 11 centers in different parts of India. The data of 183 cases were collected monthly, from June 2012 to May 2013. Of these 61 patients had stopped oral isotretinoin before surgery and 122 were concomitantly taking oral isotretinoin during the study period. In these 183 patients, a total of 504 interventions were performed. These included[1] 246 sessions of chemical peels such as glycolic acid, salicylic acid, trichloroacetic acid, and combination peels;[2] 158 sessions of lasers such as ablative fractional laser resurfacing with erbium-doped yttrium aluminum garnet and CO2, conventional full face CO2 laser resurfacing, laser-assisted hair reduction with long-pulsed neodymium-doped yttrium aluminum garnet, diode laser, and LASIK surgery;[3] 27 sessions of cold steel surgeries such as microneedling, skin biopsy, subcision, punch elevation of scars, excision of skin lesion, and wisdom tooth extraction;[4] 1 session of electrosurgery. No significant side effects were noted in most patients. 2 cases of keloid were documented which amounted to 0.4% of side effects in 504 interventions, with a significant P value of 0.000. Reversible transient side effects were erythema in 10 interventions and hyperpigmentation in 15. The study showed that performing dermatosurgical and laser procedures in patients receiving or recently received isotretinoin is safe, and the current guidelines of avoiding dermatosurgical and laser interventions in such patients taking isotretinoin need to be revised.

2. Overview showing Medical Detachment Barracks on both Ramp No. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Overview showing Medical Detachment Barracks on both Ramp No. 5 (left buildings) and Ramp No. 6 (right buildings). View is to west from roof of Corridor A. Note that a pedestrian sidewalk separates buildings instead of a street for automobiles. In left foreground is the north end of Building No. 9962-B; followed by the north B-sides of Buildings Nos. 9963, 9964, 9965, 9966, 9967 and 9968 on Ramp No. 5. Large white building in far distance is a barracks on the other side of Wilson Avenue. - Madigan Hospital, Medical Detachment Barracks, Bounded by Wilson & McKinley Avenues & Garfield & Lincoln Streets, Tacoma, Pierce County, WA

Parry-Romberg syndrome (progressive hemifacial atrophy) with spasmodic dysphonia--a rare association.

PubMed

Mugundhan, K; Selvakumar, C J; Gunasekaran, K; Thiruvarutchelvan, K; Sivakumar, S; Anguraj, M; Arun, S

2014-04-01

Parry-Romberg syndrome is a rare clinical entity characterised by progressive hemifacial atrophy with appearance of 'saber'. Various neurological and otorhinolaryngological disorders are associated with this syndrome. The association of Parry -Romberg syndrome with Spasmodic dysphonia has rarely been reported. A 37 year old female presented with progressive atrophy of tissues of left side of face for 10 years and change in voice for 1 year. On examination, wasting and atrophy of tissues including tongue was noted on left side of the face. ENT examination revealed adductor spasmodic dysphonia. We report the rare association of Parry -Romberg syndrome with spasmodic dysphonia.

Credit BG. View shows north and west sides of structure ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Credit BG. View shows north and west sides of structure as seen when looking east southeast (124°). The thick walls of this building are solid concrete, and the rooms are isolated from each other. The magazine is rated for a maximum of 100 pounds (45.4 Kg) of class 1.1 materials, and two personnel. Handles, attached to walls next to door handles, are static electric discharge points for personnel to touch before entering magazine doors. Note the lightning rods on roof corners and the exterior electrical system for interior lighting - Jet Propulsion Laboratory Edwards Facility, Igniter Magazine, Edwards Air Force Base, Boron, Kern County, CA

Surgical management of colonic diverticular disease: discrepancy between right- and left-sided diseases.

PubMed

Oh, Heung-Kwon; Han, Eon Chul; Ha, Heon-Kyun; Choe, Eun Kyung; Moon, Sang Hui; Ryoo, Seung-Bum; Jeong, Seung-Yong; Park, Kyu Joo

2014-08-07

To compare the outcome of the surgical management of left-sided and right-sided diverticular disease. The medical records of 77 patients who were surgically treated for diverticular disease between 1999 and 2010 in a tertiary referral hospital were retrospectively reviewed. The study population was limited to cases wherein the surgical specimen was confirmed as diverticulosis by pathology. Right-sided diverticula were classified as those arising from the cecum, ascending colon, and transverse colon, and those from the descending colon, sigmoid colon, and rectum were classified as left-sided diverticulosis. To assess the changing trend of occurrence of diverticulosis, data were compared with two previous studies of 51 patients. The proportion of left-sided disease cases was significantly increased compared to the results of our previous studies in 1994 and 2001, (27.5% vs 48.1%, P < 0.05). Moreover, no differences in gender, body mass index, multiplicity of the diverticula, fever, or leukocytosis were noted between patients with right-sided and left-sided disease. However, patients with right-sided disease were significantly younger (50.9 year vs 64.0 year, P < 0.01). Furthermore, left-sided disease was significantly associated with a higher incidence of complicated diverticulitis (89.2% vs 57.5%, P < 0.01), combined resection due to extensive inflammation (21.6% vs 5.0%, P < 0.05), operative complications (51.4% vs 27.5%, P < 0.05), and in-hospital mortality (10.8% vs 0%, P < 0.05), along with longer post-operative hospitalization duration (21.3 ± 10.2 d vs 10.6 ± 8.1 d, P < 0.05). Compared with right-sided diverticular disease, the incidence of left-sided disease in Korea has increased since 2001 and is associated with worse surgical outcomes.

Surgical management of colonic diverticular disease: Discrepancy between right- and left-sided diseases

PubMed Central

Oh, Heung-Kwon; Han, Eon Chul; Ha, Heon-Kyun; Choe, Eun Kyung; Moon, Sang Hui; Ryoo, Seung-Bum; Jeong, Seung-Yong; Park, Kyu Joo

2014-01-01

AIM: To compare the outcome of the surgical management of left-sided and right-sided diverticular disease. METHODS: The medical records of 77 patients who were surgically treated for diverticular disease between 1999 and 2010 in a tertiary referral hospital were retrospectively reviewed. The study population was limited to cases wherein the surgical specimen was confirmed as diverticulosis by pathology. Right-sided diverticula were classified as those arising from the cecum, ascending colon, and transverse colon, and those from the descending colon, sigmoid colon, and rectum were classified as left-sided diverticulosis. To assess the changing trend of occurrence of diverticulosis, data were compared with two previous studies of 51 patients. RESULTS: The proportion of left-sided disease cases was significantly increased compared to the results of our previous studies in 1994 and 2001, (27.5% vs 48.1%, P < 0.05). Moreover, no differences in gender, body mass index, multiplicity of the diverticula, fever, or leukocytosis were noted between patients with right-sided and left-sided disease. However, patients with right-sided disease were significantly younger (50.9 year vs 64.0 year, P < 0.01). Furthermore, left-sided disease was significantly associated with a higher incidence of complicated diverticulitis (89.2% vs 57.5%, P < 0.01), combined resection due to extensive inflammation (21.6% vs 5.0%, P < 0.05), operative complications (51.4% vs 27.5%, P < 0.05), and in-hospital mortality (10.8% vs 0%, P < 0.05), along with longer post-operative hospitalization duration (21.3 ± 10.2 d vs 10.6 ± 8.1 d, P < 0.05). CONCLUSION: Compared with right-sided diverticular disease, the incidence of left-sided disease in Korea has increased since 2001 and is associated with worse surgical outcomes. PMID:25110438

Cross-VM Side Channels and Their Use to Extract Private Keys

DTIC Science & Technology

2012-10-16

clouds such as Amazon EC2 and Rackspace, but also by other Xen use cases. For ex- 4 ample, many virtual desktop infrastructure ( VDI ) solutions (e.g...whose bit length is, for example, 337, 403, or 457 when κ is 2048 , 3072, or 4096, respectively. We note that this deviates from standard ElGamal, in

23. BUILDING NO. 452, ORDNANCE FACILITY (BAG CHARGE FILLING PLANT), ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. BUILDING NO. 452, ORDNANCE FACILITY (BAG CHARGE FILLING PLANT), INTERIOR, LOOKING SOUTH DOWN CENTRAL CORRIDOR. NOTE BINS IN WALLS ON EITHER SIDE OF CORRIDOR, USED FOR PASSING EXPLOSIVES AND LOADED ITEMS TO SIEVING ROOMS BEYOND WALLS. - Picatinny Arsenal, 400 Area, Gun Bag Loading District, State Route 15 near I-80, Dover, Morris County, NJ

Teaching Argumentation by Using Facebook Groups

ERIC Educational Resources Information Center

Delen, Ibrahim

2017-01-01

Today argumentation is widely emphasized in the policy documents in Europe, and the US. Once we look at the literature in the last two decades, many studies noted students' challenges in this process. On the other side of the coin, we see in-service teachers with problems to support this process. Unfortunately, very few studies focused on this…

VIEW OF FACILITY NO. S 20 NEAR THE POINT WHERE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF FACILITY NO. S 20 NEAR THE POINT WHERE IT JOINS FACILITY NO. S 21. NOTE THE ASPHALT-FILLED NARROW-GAUGE TRACKWAY WITH SOME AREAS OF STEEL TRACK SHOWING. VIEW FACING NORTHEAST - U.S. Naval Base, Pearl Harbor, Floating Dry Dock Quay, Hurt Avenue at northwest side of Magazine Loch, Pearl City, Honolulu County, HI

49 CFR 231.10 - Caboose cars with platforms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Caboose cars with platforms. 231.10 Section 231.10..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.10 Caboose cars with platforms. Note: a. The term “bottom of car” as used in § 231.10 is construed to mean “bottom of side-sill or...

49 CFR 231.10 - Caboose cars with platforms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Caboose cars with platforms. 231.10 Section 231.10..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.10 Caboose cars with platforms. Note: a. The term “bottom of car” as used in § 231.10 is construed to mean “bottom of side-sill or...

49 CFR 231.10 - Caboose cars with platforms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Caboose cars with platforms. 231.10 Section 231.10..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.10 Caboose cars with platforms. Note: a. The term “bottom of car” as used in § 231.10 is construed to mean “bottom of side-sill or...

49 CFR 231.10 - Caboose cars with platforms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Caboose cars with platforms. 231.10 Section 231.10..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.10 Caboose cars with platforms. Note: a. The term “bottom of car” as used in § 231.10 is construed to mean “bottom of side-sill or...

49 CFR 231.10 - Caboose cars with platforms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Caboose cars with platforms. 231.10 Section 231.10..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.10 Caboose cars with platforms. Note: a. The term “bottom of car” as used in § 231.10 is construed to mean “bottom of side-sill or...

The Seeds of Racism Within the Young Child: An American Tragedy

ERIC Educational Resources Information Center

Kranz, Peter L.; Ostler, Renee

1975-01-01

Notes that whether the young child acquires prejudice directly, indirectly, or both, his racial understanding of the "other" group is damaged as he is presented only a one-sided picture. As the young child's racist thinking becomes reinforced by significant adults, racism becomes further embedded within his "self" and he becomes a transmitter of…

15. Photocopy of photograph (from Society for the Preservation of ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. Photocopy of photograph (from Society for the Preservation of New England Antiquities, negative number 2908A) Wilfred A. French, photographer ca. 1885-1895 NORTH SIDE AND WEST FRONT (NOTE ADDITION OF DORMER ON GAMBREL ROOF OF ELL) (Illustration #11 of Data Report included in Field Records) - Narbonne House, 71 Essex Street, Salem, Essex County, MA

Anthropometric Survey of U.S. Army Personnel: Summary Statistics, Interim Report for 1988

DTIC Science & Technology

1989-03-01

measurement is taken at the maximum point of quiet respiration. Note: Breast tissue and latissimus dorsi muscle tissue are NOT included in this measurement...sides of the body; as opposed to medial (see Figure A-l). latissimus dorsi — the large muscle covering the lower half of the back above the waist and

On the Safe Side: Your Complete Reference to Childproofing for Infants & Toddlers.

ERIC Educational Resources Information Center

Wolf, Cindy

Noting that accidents are the leading cause of death among infants and children today, this book provides comprehensive guideline for preparing a safe home and caregiving environment for children from birth to around 3 years of age. Following an introduction, the chapters are organized by rooms of a house, with topics listed alphabetically within…

1. Drop Structure on the Arizona Crosscut Canal. Photographer unknown, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Drop Structure on the Arizona Crosscut Canal. Photographer unknown, no date. Note that caption is incorrect: in relation to Camelback Mountain (rear), this can only be the Old Crosscut. Source: reprinted from the 13th Annual Report of the U.S. Geological Survey, 1893. - Old Crosscut Canal, North Side of Salt River, Phoenix, Maricopa County, AZ

HORIZONTAL BEAM HOLE NO. 3. PLUG AND RADIATION DOOR HAVE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HORIZONTAL BEAM HOLE NO. 3. PLUG AND RADIATION DOOR HAVE BEEN REMOVED. EXPERIMENTAL APPARATUS WAS INSERTED INTO THE HOLE. NOTE VALVE CUBICLES NEAR FLOOR ON EACH SIDE OF HB-3. INL NEGATIVE NO. 3471. Unknown Photographer, 10/12/1951 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

Use of Avagard in pediatric urologic procedures.

PubMed

Palmer, Jeffrey S

2006-09-01

To evaluate the use of Avagard compared with a hand-brush scrub preparation by the urologist in preparation for inpatient and outpatient pediatric urologic operations. Avagard (chlorhexidine gluconate 1% solution and ethyl alcohol 61% wt/wt) is a waterless, brushless, and scrubless hand antiseptic indicated as a replacement for traditional preoperative brush hand scrubbing. We evaluated the first 550 patients for whom we used Avagard as a preoperative hand antiseptic and compared them with the last 550 consecutive patients for whom we performed traditional antiseptic-impregnated hand-brush scrubbing. All patients underwent pediatric urologic procedures. Patients were monitored postoperatively for signs of wound infection, and patients and the surgeon were monitored for side effects. A cost analysis was performed to compare the use of Avagard as a preoperative hand preparation with that of an antiseptic-impregnated hand-brush. The incidence of wound infection was one in the Avagard group and two in the hand-scrub group, not a statistically significant difference. All wound infections were successfully treated with a single course of oral antibiotics without any long-term sequelae. No side effects for the patients or surgeon were noted, including skin irritations or allergic reactions in either group. The use of Avagard was more time efficient and cost effective. To our knowledge, this is the first study demonstrating that Avagard is a fast, effective, easy to apply, and safe surgical hand preparation for pediatric urologic surgery. Its use is cost effective, as well as time efficient, in relation to the traditional surgical scrub.

Increased Jet Noise Due to a "Nominally Laminar" State of Nozzle Exit Boundary Layer

NASA Technical Reports Server (NTRS)

Zaman, K. B. M. Q.

2017-01-01

A set of 2-in. diameter nozzles is used to investigate the effect of varying exit boundary layer state on the radiated noise from high-subsonic jets. It is confirmed that nozzles involving turbulent boundary layers are the quietest while nozzles involving a "nominally laminar" boundary layer are loud especially on the high-frequency side of the sound pressure level spectrum. The latter boundary layer state involves a "Blasius-like" mean velocity profile but higher turbulence intensities compared to those in the turbulent state. The higher turbulence in the initial region of the jet shear layer leads to increased high-frequency noise. The results strongly suggest that an anomaly noted with subsonic jet noise databases in the literature is due to a similar effect of differences in the initial boundary layer state.

Increased Jet Noise Due to a "Nominally Laminar" State of Nozzle Exit Boundary Layer

NASA Technical Reports Server (NTRS)

Zaman, K. B. M. Q.

2017-01-01

A set of 2-inch diameter nozzles is used to investigate the effect of varying exit boundary layer state on the radiated noise from high-subsonic jets. It is confirmed that nozzles involving turbulent boundary layers are the quietest while nozzles involving a nominally-laminar boundary layer are loud especially on the high-frequency side of the sound pressure level spectrum. The latter boundary layer state involves a Blasius-like mean velocity profile but higher turbulence intensities compared to those in the turbulent state. The higher turbulence in the initial region of the jet shear layer leads to increased high-frequency noise. The results strongly suggest that an anomaly noted with subsonic jet noise databases in the literature is due to a similar effect of differences in the initial boundary layer state.

Occlusion therapy of unilateral amblyopia with botulinum toxin induced ptosis.

PubMed

Halkiadakis, Ioannis; Iliaki, Olga; Kalyvianaki, Maria I; Tsilimbaris, Miltiadis K

2007-01-01

In order to evaluate the role of botulinum toxin induced ptosis as an occlusion method to treat unilateral deep strabismic amblyopia in two uncooperative children, we injected 0.2 ml of diluted botulinum toxin in the levator palpaebrae; low sedation was necessary in one of the two children. In both cases a marked ptosis was achieved, which lasted about four weeks and then gradually resolved completely. The visual acuity of the ablyopic eye increased in both children, making patching easy thereafter. One child developed amblyopia in the injected eye, which was handled successfully using part-time occlusion. No other side effects were noted. Whether this new method could be a simple, safe and effective alternative method of occlusion for the treatment of deep amblyopia in uncooperative children needs to be proven with a larger series of children.

Internal impingement in the etiology of rotator cuff tendinosis revisited.

PubMed

Budoff, Jeffrey E; Nirschl, Robert P; Ilahi, Omer A; Rodin, Dennis M

2003-10-01

The theory of internal impingement holds that, in overhead athletes, repeated contact between the undersurface of the rotator cuff and the posterosuperior glenoid rim leads to articular-sided partial-thickness rotator cuff tears and superior labral lesions. However, we have noted this same constellation of lesions in our general patient population. These recreational athletic patients do not routinely assume the position of extreme abduction and external rotation, and thus are unlikely to experience significant internal impingement forces. The goal of this study was to document the prevalence of superior labral lesions in patients being treated for partial-thickness undersurface rotator cuff tears. Retrospective case series. We retrospectively reviewed the records of 75 shoulders arthroscopically treated for partial-thickness articular-sided rotator cuff tears. With the exception of one professional tennis player, no patients were playing sports at a professional or major college level. No professional or collegiate throwing athletes were included. The prevalence of these lesions and their association with recreational athletics was noted. We found that 55 of 75 (73.3%) shoulders with articular-sided partial-thickness rotator cuff tears also had superior labral lesions. A statistically significant increased prevalence of superior labral lesions in the dominant shoulder was seen (P =.03). In addition, our patients who engaged in overhand throwing had significantly fewer superior labral lesions in the dominant shoulders than did nonthrowers (P =.017). The "kissing lesions" of undersurface rotator cuff tears and posterosuperior labral damage may be explained by mechanisms other than "internal impingement."

Effects of noise and mental task performance upon changes in cerebral blood flow parameters

PubMed Central

Nowakowska-Kotas, Marta; Pokryszko-Dragan, Anna; Brodowski, Mirosław; Szydło, Mariusz; Podemski, Ryszard

2015-01-01

The objectives of this paper were to determine whether traffic noise influences the parameters of cerebral blood flow (CBF) measured by functional transcranial Doppler sonography (fTCD) during the performance of mental tasks, and to see whether impact of noise on CBF changes with age. The study comprised 36 healthy volunteers, 22 women and 14 men, aged 25-49 years. The fTCD was performed using a fixed 2-MHz probe, aiming for an evaluation of mean velocity (MFV) and the pulsatility index (PI) in the middle cerebral artery (MCA) on both sides. Subsequently, fTCD was monitored: At rest; during performance of the Paced Auditory Serial Addition Test (PASAT); during exposure to traffic noise; and during concomitant exposure to noise and PASAT performance. MFV and PI were compared for particular conditions and correlated with age. During exposure to noise, flow parameters did not change significantly. PASAT performance in silence increased MFV and decreased PI in MCA on both sides. During PASAT performance, on exposure to noise, MCV and PI changed significantly only in the left MCA. However, values of MFV were significantly lower during noise than in silence. Correlations with age were noted for velocities in the right MCA during PASAT performance in silence and for PI on both sides during PASAT performed in noise conditions. Noise impairs the CBF during mental tasks. A comparison of changes in CBF parameters correlated with age suggests that the involvement of the nondominant hemisphere in managing with noise effects increases with age. PMID:26572702

Effects of Extended Release Methylphenidate Treatment on Ratings of Attention-Deficit/Hyperactivity Disorder (ADHD) and Associated Behavior in Children with Autism Spectrum Disorders and ADHD Symptoms

PubMed Central

Santos, Cynthia W.; Aman, Michael G.; Arnold, L. Eugene; Casat, Charles D.; Mansour, Rosleen; Lane, David M.; Loveland, Katherine A.; Bukstein, Oscar G.; Jerger, Susan W.; Factor, Perry; Vanwoerden, Salome; Perez, Evelyn; Cleveland, Lynne A.

2013-01-01

Abstract Objective The purpose of this study was to examine the behavioral effects of four doses of psychostimulant medication, combining extended-release methylphenidate (MPH) in the morning with immediate-release MPH in the afternoon. Method The sample comprised 24 children (19 boys; 5 girls) who met American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV-TR) criteria for an autism spectrum disorder (ASD) on the Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS), and had significant symptoms of attention-deficit/hyperactivity disorder (ADHD). This sample consisted of elementary school-age, community-based children (mean chronological age=8.8 years, SD=1.7; mean intelligence quotient [IQ]=85; SD=16.8). Effects of four dose levels of MPH on parent and teacher behavioral ratings were investigated using a within-subject, crossover, placebo-controlled design. Results MPH treatment was associated with significant declines in hyperactive and impulsive behavior at both home and school. Parents noted significant declines in inattentive and oppositional behavior, and improvements in social skills. No exacerbation of stereotypies was noted, and side effects were similar to those seen in typically developing children with ADHD. Dose response was primarily linear in the dose range studied. Conclusions The results of this study suggest that MPH formulations are efficacious and well-tolerated for children with ASD and significant ADHD symptoms. PMID:23782128

Effects of extended release methylphenidate treatment on ratings of attention-deficit/hyperactivity disorder (ADHD) and associated behavior in children with autism spectrum disorders and ADHD symptoms.

PubMed

Pearson, Deborah A; Santos, Cynthia W; Aman, Michael G; Arnold, L Eugene; Casat, Charles D; Mansour, Rosleen; Lane, David M; Loveland, Katherine A; Bukstein, Oscar G; Jerger, Susan W; Factor, Perry; Vanwoerden, Salome; Perez, Evelyn; Cleveland, Lynne A

2013-06-01

The purpose of this study was to examine the behavioral effects of four doses of psychostimulant medication, combining extended-release methylphenidate (MPH) in the morning with immediate-release MPH in the afternoon. The sample comprised 24 children (19 boys; 5 girls) who met American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV-TR) criteria for an autism spectrum disorder (ASD) on the Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS), and had significant symptoms of attention-deficit/hyperactivity disorder (ADHD). This sample consisted of elementary school-age, community-based children (mean chronological age=8.8 years, SD=1.7; mean intelligence quotient [IQ]=85; SD=16.8). Effects of four dose levels of MPH on parent and teacher behavioral ratings were investigated using a within-subject, crossover, placebo-controlled design. MPH treatment was associated with significant declines in hyperactive and impulsive behavior at both home and school. Parents noted significant declines in inattentive and oppositional behavior, and improvements in social skills. No exacerbation of stereotypies was noted, and side effects were similar to those seen in typically developing children with ADHD. Dose response was primarily linear in the dose range studied. The results of this study suggest that MPH formulations are efficacious and well-tolerated for children with ASD and significant ADHD symptoms.

[A preliminary study of low dosage zuclopenthixol depot in Alzheimer's disease].

PubMed

Robles, A; Rodríguez Navarrete, F J; Taboada, O; Docasar, L; Páramo, M; Noya, M

1996-03-01

Persistent psychomotor agitation and psychotic ideation in patients with Alzheimer's disease are normally treated orally with antipsychotic drugs and are occasionally treated with other drugs. Neuroleptics administered intramuscularly at very low doses are an alternative, especially when the patient rejects medicine as a results of his or her anosognosia or of paranoid manifestations. We present the results we obtained after observing the effects of depot zuclopenthixol in six patients with probable Alzheimer's disease (based upon NINCDS-ADRDA criteria). Psychic abnormalities were assessed as per the Brief Psychiatric Rating Scale (BPRS), the Scale for the Assessment of Positive Symptoms (SAPS) and the Scale for the Assessment of Negative Symptoms (SANS). Possible extrapyramidal side effects were evaluated by means of the Abnormal Involuntary Movement Scale (AIMS). Initially 60 mg (0.3 ml) were administered intramuscularly and successive doses could be modified by +/-20 mg (0.1 ml) according to results seen on the various scales. During the first six weeks of treatment progressive improvement was noted on all three psychic functions scales in all patients. Between the sixth and twelfth weeks improvement continued although without significant change. The AIMS did not show significant changes in the twelve weeks of follow-up. We consider depot zuclopenthixol at low doses as efficacious in treating persistent psychomotor agitation and/or psychotic manifestations of Alzheimer's disease. No undesired side effects were observed in our group after a twelve week follow-up.

Clinical evaluation of a new 10% carbamide peroxide tooth-whitening agent.

PubMed

Barnes, D M; Kihn, P W; Romberg, E; George, D; DePaola, L; Medina, E

1998-10-01

NUPRO Gold Tooth Whitening System was evaluated for efficacy according to the proposed ADA guidelines for acceptance. Sixty participants with discolored anterior teeth participated in a 14-day, double-blind, clinical trial. The participants were matched for age, gender, and oral health status and were given either a placebo gel without the active agent or the NUPRO Gold active gel, which they wore in a custom-fabricated mouth guard for home use. The shade of each participant's maxillary anterior teeth was evaluated using a value-oriented Vita Lumin Vacuum Shade Guide before the study. The same shade guide was used to determine shade changes. Time of use of the agent and potential side effects, such as tooth and gingival hypersensitivity and tissue irritation, were assessed at all recall examinations and were recorded by participants in daily diaries. The average shade change for the placebo users was less than one shade. The average shade change for the NUPRO Gold users was 6.96 shades. Tooth hypersensitivity varied from none to severe. Tissue irritation was minimal. The results of these evaluations indicate that NUPRO Gold is effective as a tooth-whitening system, when administered properly under the supervision of a dentist, with commonly reported side effects of transient tooth sensitivity and minimal gingival sensitivity. Little or no change in tissue health was noted. This study was supported by Dentsply Preventive Care (York, Pennsylvania).

L-Dopa in Parkinsonism and the Influence of Previous Thalamotomy

PubMed Central

Hughes, R. C.; Polgar, J. G.; Weightman, D.; Walton, John N.

1971-01-01

A double-blind cross-over trial over 24 weeks (10 weeks on the active remedy, 4 weeks off treatment, and 10 weeks on placebo) of the effect of L-dopa on idiopathic Parkinsonism (paralysis agitans) has shown no difference in the response obtained in patients who had undergone previous stereotaxic ventrolateral thalamotomy and in those who had not. Of the 34 patients (18 men and 16 women) in the trial 18 had been operated on (nine unilateral, nine bilateral operations) and 16 had not. All patients entering the trial were taking anticholinergic drugs in stable dosage and these were continued throughout. The only factor which seemed to limit the response to treatment was pre-existing hypertension. Of 31 patients who completed the 10-week treatment period, 12 showed marked improvement, 15 moderate improvement, and 4 and mild or negligible change. It seems that previous ventrolateral thalamotomy affords some protection against the development of L-dopa-induced involuntary limb movements on the side contralateral to the operation. As found by others, maximum benefit was seen in bradykinesia and rigidity and related features but a significant reduction in tremor was also noted during treatment. Side effects (nausea, hypotension, and involuntary movements) were common but rarely limited the therapeutic response. PMID:4923653

Efficacy of hypofractionated radiotherapy for nasal tumours in 38 dogs (2005-2008).

PubMed

Fujiwara, A; Kobayashi, T; Kazato, Y; Yayoshi, N; Fujita, M

2013-02-01

To evaluate the efficacy of hypofractionated radiotherapy for canine nasal tumours, including the improvement in clinical signs, rate of complications and assessment of prognostic factors. Medical records of 38 dogs with malignant nasal tumours were reviewed, and those treated with a weekly schedule of hypofractionated radiotherapy were included in the study. Acute and late side effects were defined as complications noted either within 1 month or after 6 months of irradiation, respectively. Progression-free interval and overall survival were calculated using the Kaplan-Meier method. Log-rank test and Cox proportional hazard model were also performed. Clinical signs improved in 30 of 36 dogs. Acute complications were seen in 28 of 36 dogs and were considered manageable. Late complications were observed in 17 of 30 dogs that survived 6 months or longer, but severe side effects were not observed. The median progression-free interval and overall survival was 245 days (95% CI: 127-512 days) and 512 days (95% CI: 203-820 days), respectively. Age, breed and presence of dyspnoea were negatively correlated with overall survival. These results suggest that hypofractionated radiotherapy could be a viable option for the treatment of nasal tumours in dogs that are not candidates for conventional multi-fractionated radiotherapy. © 2013 British Small Animal Veterinary Association.

Early blindness alters the spatial organization of verbal working memory.

PubMed

Bottini, Roberto; Mattioni, Stefania; Collignon, Olivier

2016-10-01

Several studies suggest that serial order in working memory (WM) is grounded on space. For a list of ordered items held in WM, items at the beginning of the list are associated with the left side of space and items at the end of the list with the right side. This suggests that maintaining items in verbal WM is performed in strong analogy to writing these items down on a physical whiteboard for later consultation (The Mental Whiteboard Hypothesis). What drives this spatial mapping of ordered series in WM remains poorly understood. In the present study we tested whether visual experience is instrumental in establishing the link between serial order in WM and spatial processing. We tested early blind (EB), late blind (LB) and sighted individuals in an auditory WM task. Replicating previous studies, left-key responses were faster for early items in the list whereas later items facilitated right-key responses in the sighted group. The same effect was observed in LB individuals. In contrast, EB participants did not show any association between space and serial position in WM. These results suggest that early visual experience plays a critical role in linking ordered items in WM and spatial representations. The analogical spatial structure of WM may depend in part on the actual experience of using spatially organized devices (e.g., notes, whiteboards) to offload WM. These practices are largely precluded to EB individuals, who instead rely to mnemonic devices that are less spatially organized (e.g., recordings, vocal notes). The way we habitually organize information in the external world may bias the way we organize information in our WM. Copyright © 2016 Elsevier Ltd. All rights reserved.

Closeup oblique view of the aft fuselage of the Orbiter ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Close-up oblique view of the aft fuselage of the Orbiter Discovery looking forward and port as the last Space Shuttle Main Engine is being removed, it can be seen on the left side of the image frame. Note that one of the Orbiter Maneuvering System/ Reaction Control System has been removed while one of them remains. Also note that the body flap, below the engine positions has a protective covering to prevent damage to the High-temperature Reusable Surface Insulation tiles. This image was taken inside the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Closeup oblique view of the aft fuselage of the Orbiter ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Close-up oblique view of the aft fuselage of the Orbiter Discovery looking forward and starboard as the last Space Shuttle Main Engine is being removed, it can be seen on the right side of the image frame. Note that one of the Orbiter Maneuvering System/ Reaction Control System has been removed while one of them remains. Also note that the body flap, below the engine positions has a protective covering to prevent damage to the High-temperature Reusable Surface Insulation tiles. This image was taken inside the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Laparoscopic cholecystectomy for a left-sided gallbladder.

PubMed

Iskandar, Mazen E; Radzio, Agnes; Krikhely, Merab; Leitman, I Michael

2013-09-21

Cholecystectomy is a common procedure. Abnormalities in the anatomy of the biliary system are common but an abnormal location of the gallbladder is much rarer. Despite frequent pre-operative imaging, the aberrant location of the gallbladder is commonly discovered at surgery. This article presents a case of a patient with the gallbladder located to the left of the falciform ligament in the absence of situs inversus totalis that presented with right upper quadrant pain. A laparoscopic cholecystectomy was performed and it was noted that the cystic duct originated from the right side. The presence of a left sided gall bladder is often associated with various biliary, portal venous and other anomalies that might lead to intra-operative injuries. The spectrum of unusual positions and anatomical gallbladder abnormalities is reviewed in order to facilitate elective and emergent cholecystectomy as well as other hepatobiliary procedures. With proper identification of the anatomy, minimally invasive approaches are still considered safe.

Laparoscopic cholecystectomy for a left-sided gallbladder

PubMed Central

Iskandar, Mazen E; Radzio, Agnes; Krikhely, Merab; Leitman, I Michael

2013-01-01

Cholecystectomy is a common procedure. Abnormalities in the anatomy of the biliary system are common but an abnormal location of the gallbladder is much rarer. Despite frequent pre-operative imaging, the aberrant location of the gallbladder is commonly discovered at surgery. This article presents a case of a patient with the gallbladder located to the left of the falciform ligament in the absence of situs inversus totalis that presented with right upper quadrant pain. A laparoscopic cholecystectomy was performed and it was noted that the cystic duct originated from the right side. The presence of a left sided gall bladder is often associated with various biliary, portal venous and other anomalies that might lead to intra-operative injuries. The spectrum of unusual positions and anatomical gallbladder abnormalities is reviewed in order to facilitate elective and emergent cholecystectomy as well as other hepatobiliary procedures. With proper identification of the anatomy, minimally invasive approaches are still considered safe. PMID:24124340

Progress in the field of physiologically active lanosterol compounds

NASA Astrophysics Data System (ADS)

Reshetova, I. G.; Tkhaper, R. K.; Kamernitskii, Alexey V.

1992-08-01

This review correlates the studies (up to 1991) on the isolation, structural determination, biological activity, and synthesis of physiologically active polyoxidised lanosterol derivatives of vegetable (inotodiol, ganoderic acids) and animal (seychellogenin) origin. The cytotoxic, cardiovascular, and other forms of activity of compounds of this type are of considerable interest in relation to their medical use. It is noted that the functionalised side chain (in an open form or containing lactones, lactols, etc.) is generally responsible for the activity exhibited by lanosterol derivatives. Two basic approaches to the derivation of these structures are defined: either by complete reconstruction of the side chain of lanosterol (degradation and rebuilding with oxygen-containing residues) or by progressive functionalisation of the Δ24-side chain of lanosterol. The synthesis of the known anticancer compound "inotodiol", seychellogenins, ganoderic acids, and other compounds are described. The bibliography includes 105 references.

Churg–Strauss syndrome in a patient previously diagnosed with multiple sclerosis

PubMed Central

Sarkar, Pamela; Ibitoye, Richard Tolulope; Promnitz, Douglas Anthony

2011-01-01

A lady in her 70s with a background of multiple sclerosis (MS) and late-onset asthma was admitted with a 2-week history of cough and shortness of breath, progressive right-sided weakness and functional decline. Investigation revealed eosinophilia, elevated myeloperoxidase antineutrophil cytoplasmic antibody, CT sinuses showed long-standing inflammatory changes consistent with sinonasal polyposis and MRI head showed lesions consistent with vasculitis. She then developed left-sided weakness and increased wheeze. Review of her case notes demonstrated that, the eosinophilia was long-standing, her asthma was severe and steroid-dependent, and her neurologic syndrome was atypical for MS. Intravenous methylprednisolone then cyclophosphamide were administered. She demonstrated remarkable improvement, becoming more alert, with improvement in left-sided weakness. A diagnosis of Churg–Strauss syndrome was established. She was discharged to a nursing home with outpatient rheumatology follow-up. The diagnosis of MS was revisited. PMID:22679315

Clozapine-induced dysphagia with secondary substantial weight loss.

PubMed

Osman, Mugtaba; Devadas, Vekneswaran

2016-08-19

Dysphagia is listed as a 'rare' side effect following clozapine treatment. In this case report, we describe how significant clozapine-induced dysphagia has led to significant reduction of nutritional intake with subsequent substantial weight loss. An 18-year-old single man with an established diagnosis of treatment-resistant paranoid schizophrenia recovered well on a therapeutic dose of clozapine. However, he was noted to lose weight significantly (up to 20% of his original weight) as the dose was uptitrated. This was brought about by development of dysphagia, likely to be due to clozapine. Addition of nutritional supplementary liquids and initiation of a modified behavioural dietary/swallowing programme, while repeatedly mastering the Mendelsohn manoeuvre technique, alleviated the swallowing difficulties and restored his weight. 2016 BMJ Publishing Group Ltd.

The Use of Megestrol Acetate in Some Feline Dermatological Problems

PubMed Central

Gosselin, Y.; Chalifoux, A.; Papageorges, M.

1981-01-01

Twenty-one cats were treated with megestrol acetate because they were showing clinical signs associated with one of the following problems: eosinophilic ulcer, eosinophilic plaque, neurodermatitis, endocrine alopecia and miliary dermatitis. The dosage schedule was 5 mg orally per day per cat for seven days, then 5 mg every three days for 21 days. In all cats, we noted a good improvement of the lesions as soon as treatment was started. In 25% of the patients, one treatment schedule was sufficient to control the skin disease for at least 18 months. In the remaining 75%, two treatment schedules and/or a maintenance dosage had to be established. Side effects encountered were increased appetite, personality changes and depression. PMID:7337916

INTERIOR VIEW OF THE LIVING ROOM SHOWING THE FLOOR TO ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

INTERIOR VIEW OF THE LIVING ROOM SHOWING THE FLOOR TO CEILING WINDOWS. NOTE THE OPENING IN THE RIGHT SIDE WALL FOR AN AIR CONDITIONER. VIEW FACING SOUTHWEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, U-Shaped Three-Bedroom Duplex Type 3, Acacia Road, Birch Circle, and Cedar Drive, Pearl City, Honolulu County, HI

VIEW OF GUN EMPLACEMENT AND THE TABLELIKE CAST CONCRETE STRUCTURE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF GUN EMPLACEMENT AND THE TABLE-LIKE CAST CONCRETE STRUCTURE SHOWING THE SPALLED AREA ON ITS EAST SIDE (LEFT) WHERE THE SECOND PROJECTING ARM WAS BROKEN OFF. NOTE THE SLOPED CONCRETE PAD IN THE BACKGROUND. VIEW FACING SOUTHWEST - U.S. Naval Base, Pearl Harbor, Ford Island 5-Inch Antiaircraft Battery, East Gun Emplacement, Ford Island, Pearl City, Honolulu County, HI

View of a five inch standard Mark III model 1 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View of a five inch standard Mark III model 1 #39, manufactured in 1916 at the naval gun factory waterveliet, NY; this is the only gun remaining on olympia dating from the period when it was in commission; note ammunition lift at left side of photograph. (p36) - USS Olympia, Penn's Landing, 211 South Columbus Boulevard, Philadelphia, Philadelphia County, PA

Whistling Tea Kettles, Train Whistles, and Organ Pipes

ERIC Educational Resources Information Center

Greenslade, Thomas B., Jr.

2016-01-01

The object on the right-hand side of Fig. 1 is the whistling mechanism of an old-fashioned tea kettle. This started me thinking about similar devices in which a thin blade of air strikes a sharp wedge and a resonator is used to pick out specific frequencies. This note tells how I went about using the frequency spectrum application on a smartphone…

Transforming Teachers, Transforming Schools: Turning "Sages" into "Guides on the Side"

ERIC Educational Resources Information Center

McCrea, Steve

2012-01-01

Many teachers teach the way they were taught. If asked to explain why they lecture to their students, the response is often, "My teachers wrote on the board and I took notes. It worked for me." Brain research indicates that other techniques increase blood flow to parts of the brain associated with cognition. This presentation provides anecdotal…

A&M. Jet engine test building (TAN609). Exterior. Equipment inside rollup ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

A&M. Jet engine test building (TAN-609). Exterior. Equipment inside roll-up door is blowdown test facility, part of loft-semiscale program. Note width of central section serving as blast protection for operator on left side. Photographer: Cahoon. Date: July 22, 1965. INEEL negative no. 65-3703 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

Perspective view looking from the northeast to show east elevation ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Perspective view looking from the northeast to show east elevation and north (front) elevation; note portico on east side tucked under the extended gable roof of the wing-much like a shed roof - whereas the front has a projecting porch capped by a triangular pediment and cross-gable roof - Fort Hill, Clemson University Campus, Clemson, Pickens County, SC

More than Data: Using Interactive Science Notebooks to Engage Students in Science and Engineering

ERIC Educational Resources Information Center

Mason, Kevin; Bohl, Heather

2017-01-01

A traditional science notebook is an official record of a scientist's research. Even in today's digital world, it is still common practice for scientists to record their experimental procedures, data, analysis, results, notes, and other thoughts on the right pages of a bound notebook in permanent ink with nothing written on the left side or back…

LOFT, TAN650. Camera facing southeast. From left to right: stack ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

LOFT, TAN-650. Camera facing southeast. From left to right: stack in distance, pre-amp wing, dome, north side of loft "service building." Note poured concrete wall of pre-amp wing on lower section; pumice block above. Date: May 2004. INEEL negative no. HD-39-19-3 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

PERSPECTIVE WITH WEST PORTAL. THE BRIDGE IS CLAD IN HORIZONTAL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PERSPECTIVE WITH WEST PORTAL. THE BRIDGE IS CLAD IN HORIZONTAL CLAPBOARD SIDING AND HAS A SHEET METAL ROOF. NOTE THE TWO OPENINGS THAT RUN THE LENGTH OF THE BRIDGE; ONE IS AT THE EAVES AND THE OTHER IS ABOUT 4’ ABOVE THE DECK. - Dreibelbis Station Bridge, Spanning Maiden Creek, Balthaser Road (TR 745), Lenhartsville, Berks County, PA

Determining the Persuasiveness of Message Sidedness: A Prudent Note about Utilizing Research Summaries.

ERIC Educational Resources Information Center

Allen, Mike

1993-01-01

Responds to an analysis by D. O'Keefe (in the same issue of this journal) of a research study by the author. States that most of what O'Keefe suggests contains merit but that acceptance of the suggestions still generates a conclusion that two-sided refutational messages constitute the most persuasive form of message. (SR)

Sojourner Rover View of Pathfinder Lander

NASA Technical Reports Server (NTRS)

1997-01-01

Image of Pathfinder Lander on Mars taken from Sojourner Rover left front camera on sol 33. The IMP (on the lattice mast) is looking at the rover. Airbags are prominent, and the meteorology mast is shown to the right. Lowermost rock is Ender, with Hassock behind it and Yogi on the other side of the lander.

NOTE: original caption as published in Science Magazine

Dealing with Activism in Canada: An Ideal Cultural Fit for the Two-Way Symmetrical Public Relations Model.

ERIC Educational Resources Information Center

Guiniven, John E.

2002-01-01

Notes that disputes are seen as much less confrontational, much less zero-sum games in Canada than in the United States. Interviews 15 communications and public relations practitioners and professors with experiences on both sides of the 49th parallel and reviews relevant literature. Concludes that the greater acceptance of two-way symmetrical…

The Nervous System and Metabolic Dysregulation: Emerging Evidence Converges on Ketogenic Diet Therapy

PubMed Central

Ruskin, David N.; Masino, Susan A.

2012-01-01

A link between metabolism and brain function is clear. Since ancient times, epileptic seizures were noted as treatable with fasting, and historical observations of the therapeutic benefits of fasting on epilepsy were confirmed nearly 100 years ago. Shortly thereafter a high fat, low-carbohydrate ketogenic diet (KD) debuted as a therapy to reduce seizures. This strict regimen could mimic the metabolic effects of fasting while allowing adequate caloric intake for ongoing energy demands. Today, KD therapy, which forces predominantly ketone-based rather than glucose-based metabolism, is now well-established as highly successful in reducing seizures. Cellular metabolic dysfunction in the nervous system has been recognized as existing side-by-side with nervous system disorders – although often with much less obvious cause-and-effect as the relationship between fasting and seizures. Rekindled interest in metabolic and dietary therapies for brain disorders complements new insight into their mechanisms and broader implications. Here we describe the emerging relationship between a KD and adenosine as a way to reset brain metabolism and neuronal activity and disrupt a cycle of dysfunction. We also provide an overview of the effects of a KD on cognition and recent data on the effects of a KD on pain, and explore the relative time course quantified among hallmark metabolic changes, altered neuron function and altered animal behavior assessed after diet administration. We predict continued applications of metabolic therapies in treating dysfunction including and beyond the nervous system. PMID:22470316

A survey of cannabis (marijuana) use and self-reported benefit in men with chronic prostatitis/chronic pelvic pain syndrome.

PubMed

Tripp, Dean A; Nickel, J Curtis; Katz, Laura; Krsmanovic, Adrijana; Ware, Mark A; Santor, Darcy

2014-11-01

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a chronic pelvic pain condition largely refractory to treatment. Cannabis (marijuana) use has been reported for a wide variety of chronic pain conditions, but no study has examined prevalence of cannabis use, symptom benefit or side effects, or frequency in CP/CPPS. Participants were recruited from an outpatient CP/CPPS urology clinic (n = 98) and online through the Prostatitis Foundation website (n = 244). Participants completed questionnaires (demographics, CP/CPPS, depression, cannabis). The clinic sample included Canadian patients and the online sample included primarily American patients. Due to differences, groups were examined separately. Almost 50% of respondents reported using cannabis (clinic n = 49; online n = 89). Of the cannabis users, 36.8% of clinic and 75% of online respondents reported that it improved their symptoms. Most of the respondents (from the clinic and online groups) reported that cannabis improved their mood, pain, muscle spasms, and sleep. However, they did not note any improvements for weakness, fatigue, numbness, ambulation, and urination. Overall, the effectiveness of cannabis for CP/CPPS was "somewhat/very effective" (57% clinic; 63% online). There were no differences between side effects or choice of consumption and most reported using cannabis rarely. These are the first estimates in men suffering from CP/CPPS and suggest that while cannabis use is prevalent, its medical use and benefit are unknown. This is an understudied area and the benefit or hazard for cannabis use awaits further study.

Citalopram in the treatment of dysthymic disorder.

PubMed

Hellerstein, David J; Batchelder, Sarai; Miozzo, Ruben; Kreditor, David; Hyler, Steven; Gangure, Dinu; Clark, Joy

2004-05-01

This study aimed to provide preliminary data on the tolerability and effectiveness of citalopram for patients with dysthymic disorder. Twenty-one adult subjects meeting DSM-IV criteria for dysthymic disorder were enrolled in this 12-week open-label study, of whom 15 had pure dysthymia (e.g. no major depression in the past 2 years). Citalopram was initiated at 20 mg/day, and increased to a maximum of 60 mg/day. Response was defined as 50% or greater drop in score on the Hamilton Depression Rating Scale (HDRS) and a Clinical Global Impressions-I score of 1 ('very much improved') or 2 ('much improved'). Of these 15 pure dysthymic disorder subjects, all completed the trial, and 11 (73.3%) were treatment responders. All paired sample t-tests were highly significant, demonstrating significant average improvement on all measures of symptomatology and functioning. Scores on the 24-item HDRS decreased from 22.3+/-4.3 at baseline to 9.1+/-7.8 at week 12 [t(14)=6.1, P<0.001]. In addition, improvement was noted in self-reported measures of temperament and social functioning. The average final dose of citalopram was 39 mg/day. Side-effects were reported by nine of 15 subjects (60%), most frequently gastrointestinal symptoms (n=5), dry mouth (n=5) and sexual side-effects (n=3). These findings suggest the effectiveness and tolerability of citalopram in treating dysthymic disorder. Double-blind prospective studies are needed comparing citalopram both to placebo and to other medications, assessing both initial and sustained response to treatment.

Osteoporosis treatment: recent developments and ongoing challenges

PubMed Central

Khosla, Sundeep; Hofbauer, Lorenz C

2018-01-01

Osteoporosis is an enormous and growing public health problem. Once considered an inevitable consequence of ageing, it is now eminently preventable and treatable. Ironically, despite tremendous therapeutic advances, there is an increasing treatment gap for patients at high fracture risk. In this Series paper, we trace the evolution of drug therapy for osteoporosis, which began in the 1940s with the demonstration by Fuller Albright that treatment with oestrogen could reverse the negative calcium balance that developed in women after menopause or oophorectomy. We note a watershed in osteoporosis drug discovery around the year 2000, when the approach to developing novel therapeutics shifted from one driven by discoveries in animal studies and clinical observations (eg, oestrogen, calcitonin, and teriparatide) or opportunistic repurposing of existing compounds (eg, bisphosphonates) to one driven by advances in fundamental bone biology (eg, denosumab) coupled with clues from patients with rare bone diseases (eg, romosozumab, odanacatib). Despite these remarkable advances, concerns about rare side-effects of anti-resorptive drugs, particularly bisphosphonates, and the absence of clear evidence in support of their long-term efficacy is leading many patients who could benefit from drug therapy to not take these drugs. As such, there remains an important clinical need to develop ways to enhance patient acceptance and compliance with these effective drugs, and to continue to develop new drugs that do not cause these side-effects and have prolonged anabolic effects on bone. Such changes could lead to a true reversal of this potentially devastating disease of ageing. PMID:28689769

[Preemptive local anesthetic infiltration in hallux valgus one-day surgery].

PubMed

Gądek, Artur; Liszka, Henryk

2015-01-01

The surgical treatment of hallux valgus deformity is connected with significant postoperative pain. Spinal and general anesthesia as well as peripheral blocks are successfully used in foot surgery. The purpose of this study was to evaluate the influence of local anesthetic infiltration before hallux valgus one-day surgery on postoperative pain and the need for analgesics. 134 patients underwent chevron or miniinvasive Mitchell-Kramer osteotomy of the first distal metatarsal. After general anesthesia each patient randomly received an infiltration of 7ml of local anesthetic (4 ml of 0.25% bupivacaine and 3 ml of 2% lidocaine) or the same amount of normal saline 15 minutes before the skin incision. Both the patient and the surgeon were blinded. The patient was discharged after approximately 2 hours of observation. 2, 4, 8, 12, 16, 24 and 72 hours after the release of the tourniquet the level of pain was assessed by the visual analogue scale (VAS). Rescue analgesia, side effects and the use of painkillers were noted. Preemptive local anesthetic infiltration significantly decreased pain during the first 24 hours after the surgery. None of the patients from the injected group and 38 from the placebo group received 100 mg of ketoprofen intravenously for rescue analgesia in the first 2 hours after the release of the tourniquet. During the first 24 hours we noted significantly decreased use of 1000 mg of paracetamol and 100 mg mg of ketoprofen orally in the injected group. No systemic adverse effects were noted. One patient from placebo group had allergic rush after use of 100 mg ketoprofen. Preemptive local anesthetic infiltration in one-day hallux valgus surgery significantly decreases postoperative pain. It is safe, efficient and allows fast discharge.

2. Credit BG. The northwest and southwest sides of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Credit BG. The northwest and southwest sides of the building appear as seen when looking northeast (38°). (Photo taken from location near Building 4275/E-76, Standby Generator.) Note the extent of the barricades. On the corner of the roof at the extreme right of this view appears a small funnel; according to JPL personnel, this device collected rainwater and conducted it through a pipe which appears at the corner of the building below. The water was used to flush any wastes from the nearby drainage trenches in the exterior concrete pads. - Jet Propulsion Laboratory Edwards Facility, Weigh & Control Building, Edwards Air Force Base, Boron, Kern County, CA

ASC Weekly News Notes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Womble, David E.

Unified collision operator demonstrated for both radiation transport and PIC-DSMC. A side-by-side comparison between the DSMC method and the radiation transport method was conducted for photon attenuation in the atmosphere over 2 kilometers in physical distance with a reduction of photon density of six orders of magnitude. Both DSMC and traditional radiation transport agreed with theory to two digits. This indicates that PIC-DSMC operators can be unified with the radiation transport collision operators into a single code base and that physics kernels can remain unique to the actual collision pairs. This simulation example provides an initial validation of the unifiedmore » collision theory approach that will later be implemented into EMPIRE.« less

Endovascular Treatment of Cerebral Aneurysms in Relation to Their Parent Artery Wall: A Single Center Study

PubMed Central

Mitsos, A.P.; Giannakopoulou, M.D.; Kaklamanos, I.G.; Kapritsou, M.; Konstantinou, M.I.; Fotis, T.; Mamoura, K.V.; Mariolis-Sapsakos, T.; Ntountas, I.T.; Konstantinou, E.A.

2013-01-01

We report our two-year experience in the endovascular treatment of brain aneurysms in relation to their parent artery wall. We prospectively recorded patients with intracranial aneurysms (107 ruptured - 38 unruptured) treated with coiling during a two-year period: 145 patients, 94 females and 51 males - mean age 56 years. The aneurysms were divided into side-wall (A) and bifurcation (B) groups. A total occlusion rate was noted in post-embolization angiograms in 101 aneurysms (70%) with a morbidity of 4%. No angiographic recurrence arose in the six-month follow-up. The two groups had a similar total occlusion rate (68.31% and 71.8% respectively), while the complication rate was 3% in group A and 4.7% in group B. Significant differences between the two groups were noted in the number of assisted coiling cases: 28 out of 60 cases (46.7%) in group A - 14 out of 85 cases (16.5%) in group B. Further statistical analysis showed strong dependencies for the type of endovascular procedure between the ruptured and unruptured aneurysms in both groups (p 0.000<0.05), but no dependencies between the aneurysm occlusion rate and the ruptured or non-ruptured aneurysms, or between the occlusion rate and the type of endovascular procedure (p 0.552 >0.05 and 0.071 >0.05 respectively). In conclusion, the anatomic relation of the aneurysm sac with the wall of the parent artery is important, as significant differences in endovascular practice, devices and techniques were noted between side-wall and bifurcation aneurysms. PMID:23859171

Misoprostol dose-related shivering and pyrexia in the third stage of labour. WHO Collaborative Trial of Misoprostol in the Management of the Third Stage of Labour.

PubMed

Lumbiganon, P; Hofmeyr, J; Gülmezoglu, A M; Pinol, A; Villar, J

1999-04-01

To select the misoprostol dose to be used in a large multicentre randomised trial comparing misoprostol with oxytocin in the routine management of the third stage of labour. Randomised pilot trial, double-blinded with the use of double placebos. Two of the nine hospitals that will participate in the main multicentre trial. The hospitals were located in Johannesburg, South Africa and Khon Kaen, Thailand. Women during second stage of labour about to be delivered vaginally. The trial had three arms: misoprostol 400 microg versus misoprostol 600 microg versus intramuscular oxytocin 10 IU. Each group received an injection and three tablets immediately after the birth of the baby. Shivering and pyrexia rates were the main outcome measures. Data on other side effects and characteristics of the third stage of labour were also collected. Side effects were noted as none, mild, moderate or severe. Both shivering and pyrexia (temperature > 38 degrees C) were most common in the 600 microg misoprostol group (28% and 7.5% for shivering and pyrexia, respectively) compared with 400 microg misoprostol (19% and 2%), and the oxytocin group (12.5% and 3%). The increase in shivering in the misoprostol 600 microg group was due primarily to a higher rate of moderate shivering. None of the women had a temperature > 40 degrees C. There were no increases in severe side effects and other adverse events in the misoprostol 600 microg group. When used in the management of the third stage of labour oral misoprostol is associated with an increase in the rate of moderate shivering and pyrexia which seems to be dose-related. Based on the results of this pilot trial, the Steering Committee has decided to use 600 microg misoprostol in the main trial, comparing it with oxytocin, in order to achieve higher effectiveness.

Comparison of Q-switched Nd:YAG laser alone versus its combination with ultrapulse CO2 laser for the treatment of black tattoo.

PubMed

Vanarase, Mithila; Gautam, Ram Krishan; Arora, Pooja; Bajaj, Sonali; Meena, Neha; Khurana, Ananta

2017-10-01

Q-switched lasers are conventionally used for the treatment of black tattoo. However, they require multiple sittings, and the response may be slow due to competing epidermal pigment in dark skin. To compare the efficacy of Q-switched Nd:YAG laser alone with its combination with ultrapulse CO 2 for the removal of black tattoo. Sixty patients with black tattoo were randomized into two groups viz., group A and group B. Group A was treated with QS Nd:YAG laser (1064 nm) alone, and group B received combination of ablative ultrapulse CO 2 followed by fixed-dose QS Nd:YAG laser (1064 nm), at 6-week interval for a maximum of 6 sittings. After each sitting, 3 independent physicians noted percentage of improvement that was evaluated using visual analogue scale (VAS) and grading system for tattoo ink lightening (TIL). Combination laser (group B) showed statistically significant improvement in mean VAS score in the last 2 noted visits as compared to 1st session (p < 0.007, p < 0.001) and TIL mean score in last three noted visits as compared to 1st session (p < 0.008, p < 0.020, and p < 0.004). There was no statistically significant difference in the side effect profile of both the groups. For refractory professional tattoos, combination of ultrapulse CO 2 laser and QS Nd:YAG laser is superior to QS Nd:YAG laser alone.

Assessment of tamsulosin as a potential male contraceptive in healthy volunteers.

PubMed

Wang, Jin; Zhao, Yong; Jiang, Shao-bo; Xia, Qing-hua; Wei, Chun-xiao; Wang, Mu-wen; Sun, Peng; Jin, Xun-bo

2012-09-01

To investigate the efficacy and safety of tamsulosin, an α(1A)-adrenoceptor antagonist, as a potential male contraceptive. Forty healthy male volunteers were equally divided into 2 groups, each of which received placebo and tamsulosin sequentially in a crossover manner. Ejaculatory profile was examined 4 to 6 hours after administration and adverse effects were noted. Anejaculation occurred in all subjects after taking 0.8-mg of tamsulosin. Total functional sperm count was significantly reduced in subjects after taking 0.4-mg of tamsulosin. Six subjects receiving 0.8-mg of tamsulosin complained of tolerated discomfort, which disappeared 10 hours after administration. When administered at 0.8 mg, tamsulosin can cause anejaculation with some transient side effects. Our results imply that tamsulosin and related drugs might potentially be used as male contraceptive agents in the future, which needs more studies to verify. Copyright © 2012 Elsevier Inc. All rights reserved.

Numerical modeling of Harmonic Imaging and Pulse Inversion fields

NASA Astrophysics Data System (ADS)

Humphrey, Victor F.; Duncan, Tracy M.; Duck, Francis

2003-10-01

Tissue Harmonic Imaging (THI) and Pulse Inversion (PI) Harmonic Imaging exploit the harmonics generated as a result of nonlinear propagation through tissue to improve the performance of imaging systems. A 3D finite difference model, that solves the KZK equation in the frequency domain, is used to investigate the finite amplitude fields produced by rectangular transducers driven with short pulses and their inverses, in water and homogeneous tissue. This enables the characteristic of the fields and the effective PI field to be calculated. The suppression of the fundamental field in PI is monitored, and the suppression of side lobes and a reduction in the effective beamwidth for each field are calculated. In addition, the differences between the pulse and inverse pulse spectra resulting from the use of very short pulses are noted, and the differences in the location of the fundamental and second harmonic spectral peaks observed.

A rare case of supraventricular tachycardia induced by Infliximab: a case report

PubMed Central

2009-01-01

Background Infliximab, a chimeric monoclonal immunoglobulin antibody to tumor necrosis factor-α, has been established as a safe and effective treatment of rheumatoid arthritis, active and fistulising crohn's disease. Infliximab is generally well tolerated drug. The commonly reported cardiac side effects of Infliximab include exacerbation of congestive heart failure, hypotension and syncope. Symptomatic disorders of cardiac rhythm have been reported only rarely in few case reports and to the best of our knowledge, no tachyarrhythmia has been reported in past. Case report We report the case of a supraventricular tachycardia that occurred within three hours of Infliximab infusion in a patient with rheumatoid arthritis. Conclusion It is interesting to note that prior infusions in this patient did not precipitate similar consequences, thus, emphasising the importance of careful monitoring of patients on Infliximab therapy for possible reactions, even if prior exposures have been uneventful. PMID:19946518

Severe periorbital edema secondary to STI571 (Gleevec).

PubMed

Esmaeli, Bita; Prieto, Victor G; Butler, Charles E; Kim, Stella K; Ahmadi, M Amir; Kantarjian, Hagop M; Talpaz, Moshe

2002-08-15

STI571 (imatinib mesylate; Gleevec) is a selective inhibitor of the bcr-abl, c-kit, and platelet-derived growth factor receptor tyrosine kinases. Mild periorbital edema has been noted as a common side effect in Phase I and II trials of this drug for the treatment of patients with chronic myelogenous leukemia and gastrointestinal stromal tumors. The authors report the case of male patient age 63 years who developed severe periorbital edema after treatment with STI571 for chronic myelogenous leukemia. His edema was severe enough to cause visual obstruction due to lower eyelid festoons that ultimately required surgical debulking. Histopathologic analysis of specimens of the excised upper and lower eyelid tissue revealed dermal dendrocytes that expressed the platelet-derived growth factor receptor and c-kit tyrosine kinases, suggesting a possible role for dermal dendrocytes in the development of this toxic effect. Copyright 2002 American Cancer Society.DOI 10.1002/cncr.10729

Note-taking in the employment interview: effects on recall and judgments.

PubMed

Middendorf, Catherine Houdek; Macan, Therese Hoff

2002-04-01

Although note-taking in the employment interview is highly recommended, little research has examined its effects. This study investigated the effects of note-taking styles, review of the notes, and content of the notes on participants' cued recall of information and decisions made from videotaped employment interviews. Note-taking increased recall accuracy but not judgment accuracy. Being able to review notes resulted in increased judgment accuracy for those taking conventional-style notes. The content of the notes also had important implications for conventional note-takers, suggesting some benefits of recording notes using the key-points style. The findings suggest that the act of note-taking may be more important for memory and legal reasons than for improving the decisions made by interviewers.

The effect of visual scanning exercises integrated into physiotherapy in patients with unilateral spatial neglect poststroke: a matched-pair randomized control trial.

PubMed

van Wyk, Andoret; Eksteen, Carina A; Rheeder, Paul

2014-01-01

Unilateral spatial neglect (USN) is a visual-perceptual disorder that entails the inability to perceive and integrate stimuli on one side of the body, resulting in the neglect of one side of the body. Stroke patients with USN present with extensive functional disability and duration of therapy input. To determine the effect of saccadic eye movement training with visual scanning exercises (VSEs) integrated with task-specific activities on USN poststroke. A matched-pair randomized control trial was conducted. Subjects were matched according to their functional activity level and allocated to either a control (n = 12) or an experimental group (n = 12). All patients received task-specific activities for a 4-week intervention period. The experimental group received saccadic eye movement training with VSE integrated with task specific activities as an "add on" intervention. Assessments were conducted weekly over the intervention period. Statistical significant difference was noted on the King-Devick Test (P = .021), Star Cancellation Test (P = .016), and Barthel Index (P = .004). Intensive saccadic eye movement training with VSE integrated with task-specific activities has a significant effect on USN in patients poststroke. Results of this study are supported by findings from previously reviewed literature in the sense that the effect of saccadic eye movement training with VSE as an intervention approach has a significant effect on the visual perceptual processing of participants with USN poststroke. The significant improved visual perceptual processing translate to significantly better visual function and ability to perform activities of daily living following the stroke. © The Author(s) 2014.

Comparison of Efficacy and Safety of Intramuscular Piroxicam and Tramadol for Post-operative Pain in Patients Undergoing Caesarean Delivery.

PubMed

Thippeswamy, Tejashree; Krishnaswamy, Bhuvana; Bengalorkar, Girish M; Mariyappa, Narayanaswamy

2016-11-01

Post-caesarean section pain can be both stressful and unfavourable. Effective and rapid reduction of pain facilitates early ambulation and care of the new born. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and opioids are used for pain relief but they are associated with adverse effects both in the mother and the child. To evaluate efficacy and safety of piroxicam and tramadol in post-caesarean section pain. Primigravidae who underwent elective caesarean section received either piroxicam 20mg or tramadol 100mg intra-muscularly, following recovery from anaesthesia. Severity of pain was assessed using Visual Analogue Scale (VAS) and side-effects to study drugs were noted. Rescue analgesic butorphanol 2mg was administered if VAS score was more than four. Patient's satisfaction score was assessed at 12 hours post-operatively. Mean age in piroxicam and tramadol groups were 23.32±3.43 and 22.03±2.0 years respectively. Significant reduction in pain was observed at 2, 4, 8, 12 and 24 hours in both groups (p<0.001). Pain relief was significant at 2, 4 and 8 hours in piroxicam group compared to tramadol. Twenty-one and 12 patients in tramadol and piroxicam groups received rescue analgesic respectively. Sedation and nausea was significantly higher in tramadol group (p<0.001), 46.66% of patients graded their satisfaction score as good and 15% as excellent in piroxicam group. Intra-muscular piroxicam was effective in reducing post-caesarean section pain for 24 hours with minimal side-effects compared to tramadol.

Ketamine for chronic pain: risks and benefits

PubMed Central

Niesters, Marieke; Martini, Christian; Dahan, Albert

2014-01-01

The anaesthetic ketamine is used to treat various chronic pain syndromes, especially those that have a neuropathic component. Low dose ketamine produces strong analgesia in neuropathic pain states, presumably by inhibition of the N-methyl-D-aspartate receptor although other mechanisms are possibly involved, including enhancement of descending inhibition and anti-inflammatory effects at central sites. Current data on short term infusions indicate that ketamine produces potent analgesia during administration only, while three studies on the effect of prolonged infusion (4–14 days) show long-term analgesic effects up to 3 months following infusion. The side effects of ketamine noted in clinical studies include psychedelic symptoms (hallucinations, memory defects, panic attacks), nausea/vomiting, somnolence, cardiovascular stimulation and, in a minority of patients, hepatoxicity. The recreational use of ketamine is increasing and comes with a variety of additional risks ranging from bladder and renal complications to persistent psychotypical behaviour and memory defects. Blind extrapolation of these risks to clinical patients is difficult because of the variable, high and recurrent exposure to the drug in ketamine abusers and the high frequency of abuse of other illicit substances in this population. In clinical settings, ketamine is well tolerated, especially when benzodiazepines are used to tame the psychotropic side effects. Irrespective, close monitoring of patients receiving ketamine is mandatory, particularly aimed at CNS, haemodynamic, renal and hepatic symptoms as well as abuse. Further research is required to assess whether the benefits outweigh the risks and costs. Until definite proof is obtained ketamine administration should be restricted to patients with therapy-resistant severe neuropathic pain. PMID:23432384

A Classroom Note on Generating Examples for the Laws of Sines and Cosines from Pythagorean Triangles

ERIC Educational Resources Information Center

Sher, Lawrence; Sher, David

2007-01-01

By selecting certain special triangles, students can learn about the laws of sines and cosines without wrestling with long decimal representations or irrational numbers. Since the law of cosines requires only one of the three angles of a triangle, there are many examples of triangles with integral sides and a cosine that can be represented exactly…

Using Center of Gravity Analysis to Defeat Violent Extremist Organizations

DTIC Science & Technology

2016-04-04

elephant . They know a definition exists, but they describe it according to their own experiences.”9 Eikmeier notes “Centers of Gravity are not self... Elephant Pass demonstrated the LTTE’s ability to conduct conventional military operations.21 16...the Battle of Elephant Pass see Ahmed Hashim’s When Counterinsurgency Wins, 99- 100. 15 Analysis Both sides reached culmination leading to the

Mode Medium Interaction. A Theoretical Study.

DTIC Science & Technology

1980-09-01

Report) 10. SUPPLEMENTARY NOTES I9. KEY WORDS (Conrlfnue on reverse side II necessary mnd Identify by block rumber) CO, Laser Transfer Function...Chemical Laser Unstable Resonator Brillouin Scattering Instability Supersonic Laser Modes Acoustic Noise Acoustic Instability Perturbed Resonator Gain...end Identify by block number) An instability in the output of a high-power unstable-resonator cw CO2 laser is analyzed in terms of the perturbative

Investigation of Magnetic Field Measurements.

DTIC Science & Technology

1983-02-28

Report) Ill. SUPPLEMENTARY NOTES IS. KEY WORDS (CoEntnue on revere side I necoseer mnd Identify by block mamber) AFGL Magnetometer Network Fluxgate ... Magnetometer Induction Coil Magnetometer Temperature Dependency of Fluxgate Automation of Testing 20. ABSTRACT (Coniniue an reverse aide If neeeeey and...data collection platforms. Support was also provided to AFGL to process the fluxgate magnetometer archive tapes in order to make the data available to

ETR HEAT EXCHANGER BUILDING, TRA644. A PRIMARY COOLANT PUMP AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ETR HEAT EXCHANGER BUILDING, TRA-644. A PRIMARY COOLANT PUMP AND 24-INCH CHECK VALVE ARE MOUNTED IN A SHIELDED CUBICLE. NOTE CONNECTION AT RIGHT THROUGH SHIELD WALL TO PUMP MOTOR ON OTHER SIDE. INL NEGATIVE NO. 56-4177. Jack L. Anderson, Photographer, 12/21/1956 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

PBF Reactor Building (PER620). Camera faces south toward verticallift door, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PBF Reactor Building (PER-620). Camera faces south toward vertical-lift door, which is closed. Note crane and its trolley positioned near door; its rails along side walls. Reactor vessel and lifting beams are positioned above reactor pit. Photographer: John Capek. Date: January 9, 1970. INEEL negative no. 70-132 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

43. CUTTING APART PIECES OF A MOSAIC. WHEN SEPARATED, THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

43. CUTTING APART PIECES OF A MOSAIC. WHEN SEPARATED, THE PIECES CAN BE INDIVIDUALLY GLAZED, SMOKED, OR FINISH FIRED TO PRODUCE A MULTI-COLORED IMAGE WHEN REASSEMBLED. NOTE THE SUBSTITUTION OF BUFF FOR RED CLAY IN SEVERAL PIECES OF MOSAIC ON THE LEFT. - Moravian Pottery & Tile Works, Southwest side of State Route 313 (Swamp Road), Northwest of East Court Street, Doylestown, Bucks County, PA

New Interpretation of the Wigner Function

NASA Technical Reports Server (NTRS)

Daboul, Jamil

1996-01-01

I define a two-sided or forward-backward propagator for the pseudo-diffusion equation of the 'squeezed' Q function. This propagator leads to squeezing in one of the phase-space variables and anti-squeezing in the other. By noting that the Q function is related to the Wigner function by a special case of the above propagator, I am led to a new interpretation of the Wigner function.

European Scientific Notes. Volume 38, Number 3.

DTIC Science & Technology

1984-03-01

abrasive wear studies for a broad range of materials, includ- ing amorphous metals. OCEAN SCIENCES The Geology and Biology of Coral Reefs ...Robert Dolan 133 A meeting of the International Society for Coral Reef Studies focused on the state of the world’s reefs . Of particular concern...were diseases affecting coral reefs . Oil Spills: Can Sonar Help Investigators? ............. Chester McKinney 134 High-resolution, side-scan, bottom

Oblique view at ground level looking at the aft and ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Oblique view at ground level looking at the aft and port side of the Orbiter Discovery in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note that the Orbiter Maneuvering System/Reaction Control System pods and the Shuttle Main Engines are removed in this image. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Detail view of the underside of a elevon on the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view of the underside of a elevon on the port side wing of the Orbiter Discovery. Note the wear and replacement patterns of the High-temperature Reusable Surface Insulation tiles. This image was taken inside of the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Data and Analysis Center for Software: An IAC in Transition.

DTIC Science & Technology

1983-06-01

reviewed and is approved for publication. * APPROVEDt Proj ect Engineer . JOHN J. MARCINIAK, Colonel, USAF Chief, Command and Control Division . FOR THE CO...SUPPLEMENTARY NOTES RADC Project Engineer : John Palaimo (COEE) It. KEY WORDS (Conilnuo n rever*e aide if necessary and identify by block numober...Software Engineering Software Technology Information Analysis Center Database Scientific and Technical Information 20. ABSTRACT (Continue on reverse side It

Biological Control of Aquatic Plants with Pathogenic Fungi

DTIC Science & Technology

1981-01-01

reverse side II necoosary and Ident•l•y by block number) Aquatic plant control Fungi Aquatic plants Pathogenic fungi Biological control Waterhyacinths...BACTERIA ............. ................. D1 2 1 BIOTIGICAL CONTROL OF AQUATIC PLANTS WITH PATHOGENIC FUNGI PART I: INTRODUCTION 1. Plant pathogens have...first noted in Florida. 13. In December of 1973, Dr. K. E. Ctnway isolated a Cercospora species, along with many other fungi , from declining

38. SLABROLLING ROOM, SHOWING BISCUIT KILN No. 4 IN THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

38. SLAB-ROLLING ROOM, SHOWING BISCUIT KILN No. 4 IN THE CENTER BACKGROUND AND BISCUIT KILN No. 5 AT THE RIGHT. TILE PRESSES ARE THROUGH THE DOORWAY AT THE LEFT. NOTE THE AIR FILTER, INSTALLED IN 1986. HANGING IN THE CENTER OF THE ROOM. - Moravian Pottery & Tile Works, Southwest side of State Route 313 (Swamp Road), Northwest of East Court Street, Doylestown, Bucks County, PA

No blank slates: Pre-existing schemas about pharmaceuticals predict memory for side effects.

PubMed

Heller, Monika K; Chapman, Sarah C E; Horne, Rob

2017-04-01

Attribution of symptoms as medication side effects is informed by pre-existing beliefs about medicines and perceptions of personal sensitivity to their effects (pharmaceutical schemas). We tested whether (1) pharmaceutical schemas were associated with memory (recall/recognition) for side effect information (2) memory explained the attribution of a common unrelated symptom as a side effect. In this analogue study participants saw the patient leaflet of a fictitious asthma drug listing eight side effects. We measured recall and recognition memory for side effects and used a vignette to test whether participants attributed an unlisted common symptom (headache) as a side effect. Participants who perceived pharmaceuticals as more harmful in general recalled fewer side effects correctly (r Correct Recall  = -.273), were less able to differentiate between listed and unlisted side effects (r Recognition Sensitivity  = -.256) and were more likely to attribute the unlisted headache symptom as a side effect (r side effect attribution  = .381, ps < .01). The effect of harm beliefs on side effect attribution was partially mediated by correct recall of side effects. Pharmaceutical schemas are associated with memory for side effect information. Memory may explain part of the association between pharmaceutical schemas and the attribution of unrelated symptoms as side effects.

Occupant thorax response variations due to arm position and restraint systems in side impact crash scenarios.

PubMed

Gierczycka, Donata; Cronin, Duane S

2017-09-01

Recent epidemiological studies have identified that thoracic side airbags may vary in efficacy to reduce injury severity in side impact crash scenarios, while previous experimental and epidemiological studies have presented contrasting results. This study aimed to quantify the variations in occupant response in side impact conditions using a human body computational model integrated with a full vehicle model. The model was analyzed for a Moving Deformable Barrier side impact at 61km/h to assess two pre-crash arm positions, the incorporation of a seatbelt, and a thorax air bag on thorax response. The occupant response was evaluated using chest compression, the viscous criterion and thoracic spinal curvature. The arm position accounted for largest changes in the thorax response (106%) compared to the presence of the airbag and seatbelt systems (75%). It was also noted that the results were dependant on the method and location of thorax response measurement and this should be investigated further. Assessment using lateral displacement of the thoracic spine correlated positively with chest compression and Viscous Criterion, with the benefit of evaluating whole thorax response and provides a useful metric to compare occupant response for different side impact safety systems. The thoracic side airbag was found to increase the chest compression for the driving arm position (+70%), and reduced the injury metrics for the vertical arm position (-17%). This study demonstrated the importance of occupant arm position on variability in thoracic response, and provides insight for future design and optimization of side impact safety systems. Copyright © 2017 Elsevier Ltd. All rights reserved.

Resolution of long standing tinnitus following radiofrequency ablation of C2-C3 medial branches--a case report.

PubMed

Gritsenko, Karina; Caldwell, William; Shaparin, Naum; Vydyanathan, Amaresh; Kosharskyy, Boleslav

2014-01-01

Tinnitus is described as an auditory phantom perception analogous to central neuropathic pain. Despite the high prevalence of this debilitating symptom, no intervention is recognized that reliably eliminates tinnitus symptoms; a cause has yet to be determined. A 65-year-old healthy man presented with a 3 year history of left-sided tinnitus. Full workup performed by the primary care physician including blood tests for electrolyte imbalance, consultations by 2 independent otholaryngologists, and imaging did not reveal abnormalities to provide etiology of the tinnitus. No other complaints were noted except for occasional minimal left sided neck pain. Cervical spine x-ray showed degenerative changes with facet hypertrophy more pronounced on the left side. Subsequently, the patient underwent diagnostic left-sided C2-C3 medial branch block, resulting in complete resolution of tinnitus for more than 6 hours. After successful radiofrequency ablation of left C2-C3 medial branches, the patient became asymptomatic. At one year follow-up, he continued to be symptom free. Sparce studies have shown interaction between the somatosensory and auditory system at dorsal cochlear nucleus (DCN), inferior colliculus, and parietal association areas. Upper cervical nerve (C2) electrical stimulation evokes potentials in the DCN, eliciting strong patterns of inhibition and weak excitation of the DCN principal cells. New evidence demonstrated successful transcutaneous electrical nerve stimulation (TENS) of upper cervical nerve (C2) for treatment of somatic tinnitus in 240 patients. This case indicates that C2-C3 facet arthropathy may cause tinnitus and radiofrequency ablation of C2-C3 medial branches can provide an effective approach not previously considered.

Pain difference associated with injection of abobotulinumtoxinA reconstituted with preserved saline and preservative-free saline: a prospective, randomized, side-by-side, double-blind study.

PubMed

Allen, Shawn B; Goldenberg, Neil A

2012-06-01

The Food and Drug Administration has approved the reconstitution of botulinum toxin A with preservative-free saline. Reconstitution of onabotulinumtoxinA with preserved saline has been previously reported to decrease the pain of injections. We present the first split-face study investigating differences in subjective pain when using preserved and preservative-free saline as the reconstituent of choice for abobotulinumtoxinA. To determine whether patients notice a difference in pain when injecting abobotulinumtoxinA diluted with preserved saline versus preservative-free saline. A prospective, randomized, double-blind, side-by-side trial was conducted in a private practice dermatology office in Boulder, Colorado. Twenty volunteer patients received injections on one side of their face with abobotulinumtoxinA reconstituted with preservative-free saline and with abobotulinumtoxinA reconstituted with preserved saline on the other side. Patients reported their pain on a 10-point visual analogue pain scale after each side was injected. Patients kept a diary for the first 48 hours after treatment to track any continued pain, onset of action, or adverse events. Patients were seen at a follow-up visit at 2 weeks, and any adverse events were recorded. Ninety percent of patients reported less pain on the side injected with preserved saline than on the side injected with preservative-free saline. Pain on the preserved saline side was 60% less than on the preservative-free side. Neither the patients nor the investigators noted any difference in onset of action between the two sides. Reconstitution of abobotulinumtoxinA with preserved saline results in significantly less pain on injection than with preservative-free saline. Preserved saline may be the reconstituent of choice for reconstitution of abobotulinumtoxinA. © 2012 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.

[High-dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure].

PubMed

Tauchert, M; Gildor, A; Lipinski, J

1999-10-01

The efficacy and tolerance of the standardized hawthorn (crataegus) extract WS 1442 were tested in a multicenter utilization observational study. We monitored 1,011 patients with cardiac insufficiency stage NYHA II, treated with this extract (Crataegutt novo 450, 1 tablet b.i.d.) over a period of 24 weeks. During and at the end of the observation period a significant improvement in clinical symptoms (reduced performance in the exercise tolerance test, fatigue, palpitation and exercise dyspnea) was observed. Ankle edema and nocturia disappeared by 83%, and by half of the patients respectively manifesting these symptoms before treatment. The improvement and economization of cardiac performance were additionally shown by a reduction in blood pressure, an increased maximal exercise tolerance and a reduction in the difference in the pressure/heart rate product (PHRP). The positive effects of WS 1442 were further demonstrated by an improved ejection fraction and an increased percentile shortening fraction measured using M-mode echocardiography. The stabilizing effect of the hawthorn extract on the heart rate was shown by a slower rest pulse, as well as by an increase in the number of day and night normorhythmic patients, as documented by long-term ECG. The reduction in the number of patients showing ST depressions, arrhythmias and ventricular extrasystoles at the maximum exercise level is regarded as an indication for an improved myocardial perfusion. Fourteen side effects were noted. In two cases (abdominal discomfort and facial pains accompanied by tachycardia) a possible relationship with the hawthorn therapy, was postulated which however was considered unlikely by the treating physicians. Almost 2/3 of the patients felt better or much better following the 24 weeks of treatment. More than 3/4 of the participating physicians noted a good or a very good efficacy, and 98.7% noted a good or a very good tolerance. High-dose hawthorn therapy is an efficient, well-tolerated and easily regulated therapeutic alternative for patients suffering from cardiac insufficiency stage NYHA II.

Incisor and molar overjet, arch contraction, and molar relationship in the mixed dentition in repaired complete unilateral cleft lip and palate: A qualitative and quantitative appraisal.

PubMed

Disthaporn, Suteeta; Suri, Sunjay; Ross, Bruce; Tompson, Bryan; Baena, Diogenes; Fisher, David; Lou, Wendy

2017-07-01

To compare the mixed dentition incisor and molar overjet, severity of contraction of the dental arch, and the sagittal molar relationship on the cleft side vs the noncleft side in children with repaired complete unilateral cleft of the lip and palate (UCLP). Orthodontic records taken prior to orthodontic preparation for alveolar bone grafting were screened to select study casts from patients with nonsyndromic repaired complete UCLP who did not have mandibular skeletal or dental asymmetry. The study sample comprised dental casts from 74 children aged 8.9 ± 1 years. Standardized digital photographs were acquired at 1:1 magnification. A coordinate system was developed using digital image-processing software (Photoshop CS4 and Adobe Illustrator). Incisor and molar overjet, Angle's classification, and arch contraction were recorded. Descriptive statistics, paired t-tests, and kappa statistics were used to compare the cleft and noncleft sides. A negative overjet of -1 to -5 mm was often present at the incisors, with greater frequency and magnitude on the cleft side. Class II molar relation was more frequent on the cleft side (61.1%) than on the noncleft side (47.2%). Significantly greater contraction of the cleft side deciduous canine and deciduous first molar was noted, while the difference was very minor at the first permanent molar. Cleft side maxillary arch contraction was most severe in the deciduous canine and first deciduous molar region and progressively less severe in the posterior region of the arch. A greater frequency and severity of negative overjet and Class II molar relationship was seen on the cleft side.

Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells

PubMed Central

Golebiewska, Anna; Bougnaud, Sébastien; Stieber, Daniel; Brons, Nicolaas H. C.; Vallar, Laurent; Hertel, Frank; Klink, Barbara; Schröck, Evelin; Bjerkvig, Rolf

2013-01-01

The identification and significance of cancer stem-like cells in malignant gliomas remains controversial. It has been proposed that cancer stem-like cells display increased drug resistance, through the expression of ATP-binding cassette transporters that detoxify cells by effluxing exogenous compounds. Here, we investigated the ‘side population’ phenotype based on efflux properties of ATP-binding cassette transporters in freshly isolated human glioblastoma samples and intracranial xenografts derived thereof. Using fluorescence in situ hybridization analysis on sorted cells obtained from glioblastoma biopsies, as well as human tumour xenografts developed in immunodeficient enhanced green fluorescence protein-expressing mice that allow an unequivocal tumour-stroma discrimination, we show that side population cells in human glioblastoma are non-neoplastic and exclusively stroma-derived. Tumour cells were consistently devoid of efflux properties regardless of their genetic background, tumour ploidy or stem cell associated marker expression. Using multi-parameter flow cytometry we identified the stromal side population in human glioblastoma to be brain-derived endothelial cells with a minor contribution of astrocytes. In contrast with their foetal counterpart, neural stem/progenitor cells in the adult brain did not display the side population phenotype. Of note, we show that CD133-positive cells often associated with cancer stem-like cells in glioblastoma biopsies, do not represent a homogenous cell population and include CD31-positive endothelial cells. Interestingly, treatment of brain tumours with the anti-angiogenic agent bevacizumab reduced total vessel density, but did not affect the efflux properties of endothelial cells. In conclusion our findings contribute to an unbiased identification of cancer stem-like cells and stromal cells in brain neoplasms, and provide novel insight into the complex issue of drug delivery to the brain. Since efflux properties of endothelial cells are likely to compromise drug availability, transiently targeting ATP-binding cassette transporters may be a valuable therapeutic strategy to improve treatment effects in brain tumours. PMID:23460667

Regional repeatability measures of corneal thickness: Orbscan II and ultrasound.

PubMed

Jonuscheit, Sven; Doughty, Michael J

2007-01-01

To compare repeatability of the measures of corneal thickness obtained by slit-scanning light method (Orbscan II) with those obtained by an ultrasound pachymeter, with special interest in the peripheral region of the cornea. On 24 normal adults, aged 20 to 58 years (average 36 years) with up to -8.5 DS refractive error, three measures of corneal thickness were taken using Orbscan II and then by ultrasound pachymetry (under topical anesthesia with benoxinate 0.4%). The Orbscan central sample zone of 1 mm was selected, or the numerical maps were used to extract single point data along the horizontal corneal meridian to the nasal and temporal sides out to 4.5 mm. Ultrasound readings were taken from the central cornea and at the periphery just inside the limbus (4.5 mm from center) with a 2.4-mm diameter probe. For a central 1-mm diameter zone, the coefficient of variation (CV) for three consecutive corneal thickness measures was 0.81%+/-0.44%, but was marginally higher (p=0.004), if just the central single point data was taken with Orbscan (0.86%+/-0.45%). Similar repeatability was noted for the numerical output across the temporal side along the horizontal meridian out to 2.5 mm from the center, but farther out to 4 mm and on the nasal side the repeatability was slightly less and around 1.0% (p<0.001). Orbscan point readings of thickness could only sometimes be obtained at 4.5 mm temporally (with a poorer CV of 1.32%) and very rarely at 4.5 mm on the nasal side. No absolute differences in Orbscan repeatability were noted when comparing emmetropic with myopic subjects (p>or=0.5). Ultrasound pachymetry readings across the central zone were repeatable to 0.82%+/-0.67%. When measured with the edge of the ultrasound probe just touching the limbus, the repeatability of ultrasound readings was 1.37%+/-1.10% temporally and 1.49%+/-1.02% nasally, but neither was statistically worse that the most peripheral readings for Orbscan (p>or=0.210). However, it was also noted that the absolute values of corneal thickness, even with the application of the 0.92 acoustic factor, were 0.010 mm greater for Orbscan at the center and 0.040 mm in the corneal periphery. Orbscan II provides the clinician with a repeatable noninvasive method of measuring corneal thickness that is not necessarily any better than ultrasound pachymetry, and should not be considered as interchangeable with that for ultrasound.

Exploring the Effects of Digital Note Taking on Student Comprehension of Science Texts

ERIC Educational Resources Information Center

Horney, Mark A.; Anderson-Inman, Lynne; Terra, Fatima

2009-01-01

This study investigated the effects of text notes and voice notes on the comprehension of science texts by fifth grade students. The study was conducted to determine whether digital note taking was an effective reading strategy, and whether one form of digital note taking was more effective than the other. Results revealed that general education…

Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin?

PubMed

Giatti, Silvia; Diviccaro, Silvia; Panzica, Giancarlo; Melcangi, Roberto Cosimo

2018-04-19

Sexual dysfunction is a clinical condition due to different causes including the iatrogenic origin. For instance, it is well known that sexual dysfunction may occur in patients treated with antidepressants like selective serotonin reuptake inhibitors (SSRI). A similar side effect has been also reported during treatment with finasteride, an inhibitor of the enzyme 5alpha-reductase, for androgenetic alopecia. Interestingly, sexual dysfunction persists in both cases after drug discontinuation. These conditions have been named post-SSRI sexual dysfunction (PSSD) and post-finasteride syndrome (PFS). In particular, feeling of a lack of connection between the brain and penis, loss of libido and sex drive, difficulty in achieving an erection and genital paresthesia have been reported by patients of both conditions. It is interesting to note that the incidence of these diseases is probably so far underestimated and their etiopathogenesis is not sufficiently explored. To this aim, the present review will report the state of art of these two different pathologies and discuss, on the basis of the role exerted by three different neuromodulators such as dopamine, serotonin and neuroactive steroids, whether the persistent sexual dysfunction observed could be determined by common mechanisms.

Intraoperative bowel irrigation improves anastomotic collagen metabolism in the left-sided colonic obstruction but not covering colostomy.

PubMed

Duraker, N; Bender, O; Memişoğlu, K; Yalçiner, A

1998-01-01

This study investigated the effects of intraoperative colonic irrigation and proximal diverting end colostomy after segmental bowel resection in experimental left-colonic obstruction on anastomotic healing. Simple obstruction of descending colon was performed in male Sprague-Dawley rats. After 24 h we performed segmental colonic resection and anastomosis in the control group (n = 15); resection, anastomosis, and covering colostomy in the colostomy group (n = 14); resection and anastomosis after antegrade colonic lavage through cecum by using isotonic saline solution in the irrigation group (n = 13). In rats that were killed 7 days later anastomotic dehiscence and bursting pressure and tissue hydroxyproline concentration at the anastomosis were measured. No significant differences were observed between groups in terms of anastomotic dehiscence, bursting site, or pressure. The hydroxyproline concentration was significantly higher in the irrigation group than the control group (P = 0.025) and the colostomy group (P = 0.029), but no difference was noted between the control group and the colostomy group. These findings suggest that intraoperative antegrade colonic irrigation in the acute left-sided colonic obstruction positively affects collagen metabolism at the anastomotic site; if the anastomosis is performed without bowel cleansing, covering colostomy does not improve collagen metabolism.

Integrating medical, assistive, and universally designed products and technologies: assistive technology device classification (ATDC).

PubMed

Bauer, Stephen; Elsaesser, Linda-Jeanne

2012-09-01

ISO26000:2010 International Guidance Standard on Organizational Social Responsibility requires that effective organizational performance recognize social responsibility, including the rights of persons with disabilities (PWD), engage stakeholders and contribute to sustainable development. Millennium Development Goals 2010 notes that the most vulnerable people require special attention, while the World Report on Disability 2011 identifies improved data collection and removal of barriers to rehabilitation as the means to empower PWD. The Assistive Technology Device Classification (ATDC), Assistive Technology Service Method (ATSM) and Matching Person and Technology models provide an evidence-based, standardized, internationally comparable framework to improve data collection and rehabilitation interventions. The ATDC and ATSM encompass and support universal design (UD) principles, and use the language and concepts of the International Classification of Functioning, Disability and Health (ICF). Use ATDC and ICF concepts to differentiate medical, assistive and UD products and technology; relate technology "types" to markets and costs; and support provision of UD products and technologies as sustainable and socially responsible behavior. Supply-side and demand-side incentives are suggested to foster private sector development and commercialization of UD products and technologies. Health and health-related professionals should be knowledgeable of UD principles and interventions.

Using non-linear analogue of Nyquist diagrams for analysis of the equation describing the hemodynamics in blood vessels near pathologies

NASA Astrophysics Data System (ADS)

Cherevko, A. A.; Bord, E. E.; Khe, A. K.; Panarin, V. A.; Orlov, K. J.; Chupakhin, A. P.

2016-06-01

This article considers method of describing the behaviour of hemodynamic parameters near vascular pathologies. We study the influence of arterial aneurysms and arteriovenous malformations on the vascular system. The proposed method involves using generalized model of Van der Pol-Duffing to find out the characteristic behaviour of blood flow parameters. These parameters are blood velocity and pressure in the vessel. The velocity and pressure are obtained during the neurosurgery measurements. It is noted that substituting velocity on the right side of the equation gives good pressure approximation. Thus, the model reproduces clinical data well enough. In regard to the right side of the equation, it means external impact on the system. The harmonic functions with various frequencies and amplitudes are substituted on the right side of the equation to investigate its properties. Besides, variation of the right side parameters provides additional information about pressure. Non-linear analogue of Nyquist diagrams is used to find out how the properties of solution depend on the parameter values. We have analysed 60 cases with aneurysms and 14 cases with arteriovenous malformations. It is shown that the diagrams are divided into classes. Also, the classes are replaced by another one in the definite order with increasing of the right side amplitude.

Ketamine PCA for treatment of end-of-life neuropathic pain in pediatrics.

PubMed

Taylor, Matthew; Jakacki, Regina; May, Carol; Howrie, Denise; Maurer, Scott

2015-12-01

Control of neuropathic pain (NP) for children at end of life is challenging. Ketamine improves control of NP, but its use in children is not well described. We describe a retrospective case review of 14 children with terminal prognoses treated with ketamine patient-controlled analgesia (PCA) for management of opioid-refractory NP at the end of life. Median ketamine dose was 0.06 mg/kg/h (range 0.014-0.308 mg/kg/h) with a 0.05 mg/kg (range 0.03-0.5mg/kg) demand dose available every 15 minutes (range 10-60 minutes). All patients noted subjective pain relief with ketamine, and 79% had no adverse effects. Benzodiazepines limited neuropsychiatric side effects. Ketamine treatment arrested dose escalation of opioids in 64% of patients, and 79% were discharged to home hospice. Ketamine PCA is an effective, well-tolerated therapy for opioid-refractory NP in pediatric end-of-life care. © The Author(s) 2014.

Trihexyphenidyl improves motor function in children with dystonic cerebral palsy: a retrospective analysis.

PubMed

Ben-Pazi, Hilla

2011-07-01

There are conflicting reports regarding the efficacy of trihexyphenidyl, an anticholinergic drug, for treatment of dystonia in cerebral palsy. The author hypothesized that trihexyphenidyl may be more effective in specific subgroups and performed a retrospective analysis of 31 children (8.2 ± 5.8 years) with dystonia following treatment with high-dose trihexyphenidyl (>0.5 mg/kg/day). Main outcome measure was extent of motor improvement calculated according to the body areas affected. Most (21/31) caregivers reported improvement in 1 or more areas, mainly arm, hand, and oromotor function. Improvement was greater in children without spasticity (P = .02) and in those with higher cognitive function (P = .02). While a third of caregivers (10/31) reported tone reduction, and half (15/31) noted overall functional improvement. Side effects were transient, with the exception of hyperopia (n = 1), and occurred less frequently in children with a history of prematurity (P = .02). In summary, trihexyphenidyl is effective particularly in absence of spasticity and in children with higher cognitive abilities.

Ingestion of an Oral Hyaluronan Solution Improves Skin Hydration, Wrinkle Reduction, Elasticity, and Skin Roughness: Results of a Clinical Study.

PubMed

Göllner, Imke; Voss, Werner; von Hehn, Ulrike; Kammerer, Susanne

2017-10-01

Intake of oral supplements with the aim of a cutaneous antiaging effect are increasingly common. Hyaluronic acid (HA) is a promising candidate, as it is the key factor for preserving tissue hydration. In our practice study, we evaluated the effect of an oral HA preparation diluted in a cascade-fermented organic whole food concentrate supplemented with biotin, vitamin C, copper, and zinc (Regulatpro Hyaluron) on skin moisture content, elasticity, skin roughness, and wrinkle depths. Twenty female subjects with healthy skin in the age group of 45 to 60 years took the product once daily for 40 days. Different skin parameters were objectively assessed before the first intake, after 20 and after 40 days. Intake of the HA solution led to a significant increase in skin elasticity, skin hydration, and to a significant decrease in skin roughness and wrinkle depths. The supplement was well tolerated; no side effects were noted throughout the study.

The Desmethyl Metabolite of Imipramine (G-35020) in the Treatment of Depression: Further Clinical Experience.

PubMed

Mann, A M; Heseltine, G F

1963-06-01

The desmethyl metabolite of imipramine (DMI) was used to treat 103 depressed patients, standard dosage being 50 mg. thrice daily orally. Seventy patients recovered or were much improved. The indication for DMI and its activity spectrum were of the same order as imipramine. Side effects were less frequent and less severe. Average onset of definitive improvement was three days; earliest changes noted were in facies, motility, and relief of guilt feelings. Besides the classical straightforward response, seven patients improved early but relapsed, and 12 showed a "plateau effect". Absence of favourable response after seven days necessitated reevaluation and/or substitution of other approaches. DMI may be the drug of choice in initiating treatment of depression, but seemed insufficient alone to deal with agitated, acutely suicidal patients. Although DMI appeared an effective, fast-acting antidepressant, there is still no panacea for this ubiquitous syndrome, whose proper management calls for flexibility and awareness of its multifactorial etiology.

Matrine Induction of ROS Mediated Apoptosis in Human ALL B-lymphocytes Via Mitochondrial Targeting

PubMed Central

Aghvami, Marjan; Ebrahimi, Fatemeh; Zarei, Mohammad Hadi; Salimi, Ahmad; Jaktaji, Razieh Pourahmad; Pourahmad, Jalal

2018-01-01

Background: Acute lymphoblastic leukemia (ALL) is one of the most common malignancies among children, characterized by mass production of leukemic blasts. Chemotherapy is the first step in routine treatment, although it may evoke considerable side effects. Matrine, an alkaloid extracted from a Chinese herb, Sophora alopecuroides flavescens Ait, may be protective. Several investigations have indicated pro-apoptotic and anti-proliferative effects in a diverse range of cancer cells. Methods: Matrine’s anti-cancer effects and associated mechanisms were assessed in human ALL B-lymphocytes, focusing on parameters of inflammatory change and apoptosis. Results: Treatment of ALL B-lymphocytes with matrine augmented ROS generation, and caused mitochondrial swelling and a decline in mitochondrial membrane potential. Significant up-regulation of the pro-apoptotic protein Bax and down-regulation of the anti-apoptotic Bcl-2 were also noted. Conclusion: Our results suggest that matrine may be a potential anticancer agent. However, additional studies are needed to clarify involved mechanisms. PMID:29481011

Ingestion of an Oral Hyaluronan Solution Improves Skin Hydration, Wrinkle Reduction, Elasticity, and Skin Roughness: Results of a Clinical Study

PubMed Central

Göllner, Imke; Voss, Werner; von Hehn, Ulrike; Kammerer, Susanne

2017-01-01

Intake of oral supplements with the aim of a cutaneous antiaging effect are increasingly common. Hyaluronic acid (HA) is a promising candidate, as it is the key factor for preserving tissue hydration. In our practice study, we evaluated the effect of an oral HA preparation diluted in a cascade-fermented organic whole food concentrate supplemented with biotin, vitamin C, copper, and zinc (Regulatpro Hyaluron) on skin moisture content, elasticity, skin roughness, and wrinkle depths. Twenty female subjects with healthy skin in the age group of 45 to 60 years took the product once daily for 40 days. Different skin parameters were objectively assessed before the first intake, after 20 and after 40 days. Intake of the HA solution led to a significant increase in skin elasticity, skin hydration, and to a significant decrease in skin roughness and wrinkle depths. The supplement was well tolerated; no side effects were noted throughout the study. PMID:29228816

The Impact of Virtual Reality on Chronic Pain.

PubMed

Jones, Ted; Moore, Todd; Choo, James

2016-01-01

The treatment of chronic pain could benefit from additional non-opioid interventions. Virtual reality (VR) has been shown to be effective in decreasing pain for procedural or acute pain but to date there have been few studies on its use in chronic pain. The present study was an investigation of the impact of a virtual reality application for chronic pain. Thirty (30) participants with various chronic pain conditions were offered a five-minute session using a virtual reality application called Cool! Participants were asked about their pain using a 0-10 visual analog scale rating before the VR session, during the session and immediately after the session. They were also asked about immersion into the VR world and about possible side effects. Pain was reduced from pre-session to post-session by 33%. Pain was reduced from pre-session during the VR session by 60%. These changes were both statistically significant at the p < .001 level. Three participants (10%) reported no change between pre and post pain ratings. Ten participants (33%) reported complete pain relief while doing the virtual reality session. All participants (100%) reported a decrease in pain to some degree between pre-session pain and during-session pain. The virtual reality experience was found here to provide a significant amount of pain relief. A head mounted display (HMD) was used with all subjects and no discomfort was experienced. Only one participant noted any side effects. VR seems to have promise as a non-opioid treatment for chronic pain and further investigation is warranted.

Hip-flexed postures do not affect local anaesthetic spread following induction of epidural analgesia for labour.

PubMed

Ducloy-Bouthors, A S; Davette, M; Le Fahler, G; Devos, P; Depret-Mosser, S; Krivosic-Horber, R

2004-04-01

Hip-flexed postures enlarging the pelvic diameter are used to improve the obstetric course of labour. Although most investigations show that lateral and sitting positions do not affect the spread of epidural analgesia, the effect of recently introduced hip-flexed postures has yet to be confirmed. This prospective randomised study included 93 parturients. Ropivacaine 0.1% 12 mL plus sufentanil 0.5 micrograms/mL was administered epidurally over a period of 6 min in one of four postures: sitting, right hip-flexed left lateral position, left hip-flexed right lateral position and supine 30 degrees lateral tilt as a control group. Left and right cephalad and sacral epidural spread were measured every 2 min over a period of 30 min. Pain relief, motor blockade and maternal and fetal side effects were noted. The total epidural spread was 15+/-0.3 dermatomes and the upper level of thermo-algesic blockade T7-T8 (range T3 to T10) in all groups. There were no differences between groups in left or right total spread or upper level of epidural blockade, time to maximal block or pain relief. There was no motor block nor any maternal or fetal side effects. The power of the study (1 - beta) was 93%. We conclude that, for the three hip-flexed postures tested, position does not influence local anaesthetic spread or symmetry of thermo-algesic blockade after induction of obstetric epidural analgesia.

A rare side effect of transesophageal echocardiography: methemoglobinemia from topical benzocaine anesthesia.

PubMed

Jaffery, Zehra; Ananthasubramaniam, Karthik

2008-03-01

Benzocaine induced methemoglobinemia is an uncommon, potentially fatal condition. A 44-year-old woman with a history of hepatitis C and intravenous drug use was referred for transesophageal echocardiography for bacteremia evaluation. During induction of topical anesthesia with benzocaine spray she became cyanotic. Pulse oximetry revealed marked desaturation (75%) but was discordant from arterial blood O(2) saturation (99%). Due to clinical suspicion, methemoglobin level was measured and noted to be 69%. The patient was treated with 2 mg/kg of methylene blue intravenously with resolution of her symptoms. Physicians using topical anesthesia in endoscopic suites should be aware of this rare, potentially life-threatening treatable condition. High clinical suspicion and availability of methylene blue in endoscopy suites will facilitate prompt diagnosis and treatment.

A NEW ANTIEMETIC FOR THE TREATMENT OF NAUSEA AND VOMITING ASSOCIATED WITH ROENTGEN THERAPY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Codiga, V.A.

Thiethylperazine dimaleate was administered orally or rectally in 56 patients for treatment of nausea or vomiting associated with radiation (2000 to 5000 r). The oral form had a quicker onset of action. Fifty patients (89%) experienced satisfactory response with either oral tablets or suppositories, the latter being used when oral tolerance was poor. Only 2 complained of side effects attributable to thiethylperazine dimaleate. One patient experienced transient blurred vision and tinnitus and another noted sialorrhea plus diminished gustatory sensation. In view of the observed high percentage of favorable responses with the drug and its lack of ataractic action, the rolemore » of psychogenic factors in gastrointestinal disturbance associated with roentgen ray therapy would seem to be slight. (H.H.D.)« less

Urea for long-term treatment of syndrome of inappropriate secretion of antidiuretic hormone.

PubMed Central

Decaux, G; Genette, F

1981-01-01

The efficacy of oral urea in producing a sufficiently high osmotic diuresis was tested in seven patients with the syndrome of inappropriate secretion of antidiuretic hormone. In all patients urea corrected the hyponatraemia despite a normal fluid intake. Five patients were controlled (serum sodium concentration greater than 128 mmol(mEq)/1) with a dose of 30 g urea daily, and two with 60 g daily. The patients who needed 30 g drank 1-2 1 of fluid daily, while those who needed 60 g drank up to 3.1 per day. No major side effects were noted, even after treatment periods of up to 270 days. These findings suggest that urea is a safe and efficacious treatment of the syndrome of inappropriate secretion of antidiuretic hormone. PMID:6794768

Urea for long-term treatment of syndrome of inappropriate secretion of antidiuretic hormone.

PubMed

Decaux, G; Genette, F

1981-10-24

The efficacy of oral urea in producing a sufficiently high osmotic diuresis was tested in seven patients with the syndrome of inappropriate secretion of antidiuretic hormone. In all patients urea corrected the hyponatraemia despite a normal fluid intake. Five patients were controlled (serum sodium concentration greater than 128 mmol(mEq)/1) with a dose of 30 g urea daily, and two with 60 g daily. The patients who needed 30 g drank 1-2 1 of fluid daily, while those who needed 60 g drank up to 3.1 per day. No major side effects were noted, even after treatment periods of up to 270 days. These findings suggest that urea is a safe and efficacious treatment of the syndrome of inappropriate secretion of antidiuretic hormone.

Analysis of cryogenic propellant behavior in microgravity and low thrust environments

NASA Technical Reports Server (NTRS)

Fisher, Mark F.; Schmidt, George R.; Martin, James J.

1991-01-01

Predictions of a CFD program calculating a fluid-free surface shape and motion as a function of imposed acceleration are validated against the drop-tower test data collected to support design and performance assessments of the Saturn S-IVB stage liquid-hydrogen tank. The drop-tower facility, experimental package, and experiment procedures are outlined, and the program is described. It is noted that the validation analysis confirms the program's suitability for predicting low-g fluid slosh behavior, and that a similar analysis could examine the effect of incorporating baffles and screens to impede initiation of any unwanted side loads due to slosh. It is concluded that in actual vehicle applications, the engine thrust tailoff profile should be included in computer simulations if the precise interface versus time definition is needed.

Effects of 3-Day Serial Sodium Bicarbonate Loading on Performance and Physiological Parameters During a Simulated Basketball Test in Female University Players.

PubMed

Delextrat, Anne; MacKessy, Sinead; Arceo-Rendon, Luis; Scanlan, Aaron; Ramsbottom, Roger; Calleja-González, Julio

2018-01-18

The aim of this study was to investigate the effect of 3-day serial sodium bicarbonate ingestion on repeated sprint and jump performance. Fifteen female university basketball players (23.3±3.4 years; 173.1±5.8 cm; 65.8±6.3 kg; 23.6±4.9% body fat) ingested 0.4 g·kg -1 of body mass of sodium bicarbonate or placebo for 3 days (split in 3 equal daily doses), before completing a simulated basketball exercise. Sprint and circuit times, jump heights, performance decrements and gastrointestinal (GI) side effects were recorded during the test and blood lactate concentration was measured pre- and post-test. Sodium bicarbonate supplementation led to significant decreases in mean sprint times (1.34±0.23 vs. 1.70±0.41 s, p=0.008, 95% CI: -0.54 to -0.10 s) and mean circuit times (30.6±2.0 vs. 31.3±2.0 s, p=0.044) and significantly greater mean jump height (26.8 (range 25.2-34.2) vs. 26.0 (range 25.6-33.6) cm, p=0.013) compared to placebo. Performance decrement was significantly less for sprints with sodium bicarbonate compared to placebo (9.9 (range 3.4-37.0) vs. 24.7 (range 4.1-61.3) %, p=0.013), but not different for jumps (13.1±4.5 vs. 12.5±.3.1%, p=0.321) between conditions. No differences in GI side effects were noted between conditions. Significantly greater post-exercise blood lactate concentrations were measured in the sodium bicarbonate condition compared to the placebo condition (8.2±2.8 vs. 6.6±2.4 mmol.L -1 , p=0.010). This study is the first to show that serial loading of sodium bicarbonate is effective for basketball players to improve repeated sprint and jump performance during competition, or withstand greater training load during practice sessions without any GI side effects.

Present Status of Medical Education in Poland

PubMed Central

Selzer, Arthur

1965-01-01

In the past few years medical education in Poland has undergone considerable change, particularly at the graduate and postgraduate levels, and has shown increasing Western influences. On the negative side, a physician who was trained in pre-war Poland and is now in the United States, noted mass production of physicians with modest clinical facilities and the preponderance of didactic lecturing over semi-individual instruction—conditions rather characteristic of most European medical schools. On the positive side were well-informed, up-to-date faculties and the thoughtful planning and organization of graduate and postgraduate medical education. The overall impression was a favorable one, but the system of schooling and of evaluation of students' work made it possible for indifferent students to progress to licensure. PMID:14288146

PRESENT STATUS OF MEDICAL EDUCATION IN POLAND.

PubMed

SELZER, A

1965-04-01

In the past few years medical education in Poland has undergone considerable change, particularly at the graduate and postgraduate levels, and has shown increasing Western influences. On the negative side, a physician who was trained in pre-war Poland and is now in the United States, noted mass production of physicians with modest clinical facilities and the preponderance of didactic lecturing over semi-individual instruction-conditions rather characteristic of most European medical schools. On the positive side were well-informed, up-to-date faculties and the thoughtful planning and organization of graduate and postgraduate medical education. The overall impression was a favorable one, but the system of schooling and of evaluation of students' work made it possible for indifferent students to progress to licensure.

4. EXTERIOR VIEW OF HILLMAN FAN HOUSE LOOKING NORTHEAST This ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. EXTERIOR VIEW OF HILLMAN FAN HOUSE LOOKING NORTHEAST This view shows the concrete roof covering the airways and the engine room. The reinforced concrete roof is supported by metal beams. Note how the airshaft, in the foreground, widens to create an airway on either side for the double inlet fan. The brick fan housing is capped by a curved sheet metal roof whose segments are bolted together. The brick updraft chimney, capped with concrete, is to the rear (northeast). Also evident on the wall is the cover over the air velocity indicator. The Hollenback Cemetery, which adjoins the Dorrance Colliery property is in the background. - Dorrance Colliery Fan Complex, South side of Susquehanna River at Route 115 & Riechard Street, Wilkes-Barre, Luzerne County, PA

Effects of variables upon pyrotechnically induced shock response spectra

NASA Technical Reports Server (NTRS)

Smith, J. L.

1986-01-01

Throughout the aerospace industry, large variations of 50 percent (6 dB) or more are continually noted for linear shaped charge (LSC) generated shock response spectra (SRS) from flight data (from the exact same location on different flights) and from plate tests (side by side measurements on the same test). A research program was developed to investigate causes of these large SRS variations. A series of ball drop calibration tests to verify calibration of accelerometers and a series of plate tests to investigate charge and assembly variables were performed. The resulting data were analyzed to determine if and to what degree manufacturing and assembly variables, distance from the shock source, data acquisition instrumentation, and shock energy propagation affect the SRS. LSC variables consisted of coreload, standoff, and apex angle. The assembly variable was the torque on the LSC holder. Other variables were distance from source of accelerometers, accelerometer mounting methods, and joint effects. Results indicated that LSC variables did not affect SRS as long as the plate was severed. Accelerometers mounted on mounting blocks showed significantly lower levels above 5000 Hz. Lap joints did not affect SRS levels. The test plate was mounted in an almost free-free state; therefore, distance from the source did not affect the SRS. Several varieties and brands of accelerometers were used, and all but one demonstrated very large variations in SRS.

Evaluation of gait performance of a participant with Perthes disease while walking with and without a Scottish-Rite orthosis.

PubMed

Karimi, Mohammad; Sedigh, Jafar; Fatoye, Francis

2013-06-01

Scottish-Rite orthosis is one of the conservative methods used to treat Legg-Calvé-Perthes disease. As there was not enough evidence to show the effects of using this orthosis on reducing the loads applied on the limb, this research aimed to find the influence of this orthosis. A participant with Perthes disease on the left hip joint was recruited into this study to walk with and without the orthosis. The kinetic and kinematic parameters were collected by a motion analysis system and a Kistler force platform. No significant differences were noted between the hip joint flexion/extension range of motion and the moments between the sound side and the side affected by Legg-Calvé-Perthes disease. It may be concluded that use of orthosis may not have any positive effects to decrease the loads or to improve the alignment of the hip joint in participants with Perthes disease, as expected. The use of Scottish-Rite orthosis not only does not improve the containment of the hip joint, but also does not have any significant influence on loads applied on the joint during walking of the subject with Perthes disease. The results of this research can be used by clinicians involved in treatment of patients with Legg-Calvé-Perthes disease.

Topical Medical Cannabis: A New Treatment for Wound Pain-Three Cases of Pyoderma Gangrenosum.

PubMed

Maida, Vincent; Corban, Jason

2017-11-01

Pain associated with integumentary wounds is highly prevalent, yet it remains an area of significant unmet need within health care. Currently, systemically administered opioids are the mainstay of treatment. However, recent publications are casting opioids in a negative light given their high side effect profile, inhibition of wound healing, and association with accidental overdose, incidents that are frequently fatal. Thus, novel analgesic strategies for wound-related pain need to be investigated. The ideal methods of pain relief for wound patients are modalities that are topical, lack systemic side effects, noninvasive, self-administered, and display rapid onset of analgesia. Extracts derived from the cannabis plant have been applied to wounds for thousands of years. The discovery of the human endocannabinoid system and its dominant presence throughout the integumentary system provides a valid and logical scientific platform to consider the use of topical cannabinoids for wounds. We are reporting a prospective case series of three patients with pyoderma gangrenosum that were treated with topical medical cannabis compounded in nongenetically modified organic sunflower oil. Clinically significant analgesia that was associated with reduced opioid utilization was noted in all three cases. Topical medical cannabis has the potential to improve pain management in patients suffering from wounds of all classes. Copyright © 2017 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

Levetiracetam monotherapy for treatment of structural epilepsy in dogs: 19 cases (2010-2015).

PubMed

Kelly, Darren; Raimondi, Francesca; Shihab, Nadia

2017-10-14

To evaluate the efficacy and tolerability of levetiracetam monotherapy in dogs with structural epilepsy. Retrospective case series. Nineteen client-owned dogs with structural epilepsy. Seizure frequencies after initiation of treatment were used to evaluate the efficacy of levetiracetam monotherapy. Seizure control was considered good if no seizures occurred within three months of starting treatment or poor if seizures returned within one month of starting treatment. Tolerability was evaluated by considering the occurrence and severity of any reported side effects. Ten of the 19 dogs were considered to have a good response to treatment with 7 achieving complete seizure freedom. Nine dogs were considered to have poor response to treatment. There was a statistically significant reduction in the percentage of patients experiencing cluster seizures from 68.4% to 15.8% (p=0.002). Side effects were noted in 8 of the 19 dogs but were considered mild in all cases. Follow-up times ranged from 12 days to 426 days. When used in conjunction with other appropriate therapies, levetiracetam may be an efficacious option for monotherapy in dogs with structural epilepsy. Its tolerability makes it a suitable option for use in a wide variety of patients. © British Veterinary Association (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Adolescents' experiences using the contraceptive patch versus pills.

PubMed

Sucato, Gina S; Land, Stephanie R; Murray, Pamela J; Cecchini, Reena; Gold, Melanie A

2011-08-01

To compare use of the weekly transdermal contraceptive patch (patch) with daily combined hormonal contraceptive pills (pills) in adolescents. Prospective longitudinal study of adolescents' self-selected (non-randomized) use of the patch or pills. Urban, university hospital-affiliated, adolescent outpatient clinic. 13-22-year-old female adolescents seeking hormonal contraception, 40 who chose the patch and 40 who chose pills. Data were collected via self-report on paper questionnaires at three-cycle intervals for a total of up to nine cycles. Method continuation, perfect use, method satisfaction, quality of life, and side effects, including menstrual changes and perceived mood changes. After nine cycles, 38% of patch users and 60% of pill users were still using the method they had chosen at enrollment. There were no significant differences between the groups in self-reported perfect use. No differences were found in quality of life or side effects. Both patch and pill users noted menses became lighter and more predictable and reported decreased depression prior to their menses; only the pill group reported improvement in premenstrual anger. Method satisfaction was similar in both groups except patch users were more likely to report that their contraceptive method improved normal daily activities. Despite apparent advantages of the patch over the pill, adolescents using both methods continue to face challenges achieving perfect and sustained contraceptive use. 2011 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

Redescription of the Advertisement Call of Five Species of Thoropa (Anura, Cycloramphidae), Including Recordings of Rare and Endangered Species.

PubMed

Nunes-de-Almeida, Carlos H L; Assis, Clodoaldo L; Feio, Renato N; Toledo, Luís Felipe

2016-01-01

Frogs of the genus Thoropa comprise six endemic Brazilian species on the Eastern side of the country. Little is known about their natural history, especially about their acoustic communication. Therefore, aiming to provide an overview of their vocalizations, we analyzed and redescribed male advertisement calls of three living and two possibly extinct species. The smaller species, T. petropolitana and T. lutzi, produce simple calls (one single note) with a higher frequency range than the remaining larger ones. On the other hand, the larger species present complex calls, with more than one note: T. megatympanum calls have three notes, T. taophora calls have four notes, and T. miliaris calls varies from three to six notes. Population snout-vent length negatively correlated with peak of dominant frequency as expected. However, highlighted differences between two populations of T. lutzi, which could indicate need of further taxonomic evaluation of those lineages. Peculiar morphology, such as the absence of vocal sacs and slits, may have contributed to their call variation and highly banded frequency structure. If the observed population differences reflect species-level differences, T. lutzi may be classified as a critically endangered species, as T. petropolitana. Furthermore, we provided a suggestion to an unusual behavior in frogs: calling with the mouth open in the smaller species of the genus.

Front-Row Seat at the IPY: The Field Notes Electronic Newsletter

NASA Astrophysics Data System (ADS)

Rithner, P. K.; Zager, S. D.; Garcia-Lavigne, D. N.

2007-12-01

As employees of Polar Field Services/VPR, the arctic logistics provider to the US National Science Foundation, we bear witness to the exploration, documentation, and celebration of the International Polar Year (IPY). Our front- row vantage point (logisticians working with field scientists) offers us a rare opportunity to report on developments at the frontiers of polar research and to describe how scientists work in the Arctic. Our reporting mechanism is field notes, a weekly (summer) to monthly (winter) electronic digest of information about the IPY research we support. Each issue showcases a short "cover" piece highlighting science projects or profiling arctic program participants. In addition, field notes offers news updates, short interviews, and blog-style dispatches contributed by researchers and support personnel. Wherever possible, we include URLs so readers may find more information via the Web: we link to an online database of projects we maintain for the NSF, to university Web sites, project blogs, and so on. We aim to inform the interested layperson about the myriad of activity in the IPY. We like to show that arctic science is interesting, relevant--and a great adventure. We've found field notes to be an excellent outreach venue. By no means a slick media outlet, field notes is published "on the side" by a small but dedicated group of employees who are endlessly fascinated by, and who enjoy an engaging perspective on, contemporary arctic research. Newsletter

Redescription of the Advertisement Call of Five Species of Thoropa (Anura, Cycloramphidae), Including Recordings of Rare and Endangered Species

PubMed Central

Assis, Clodoaldo L.; Feio, Renato N.; Toledo, Luís Felipe

2016-01-01

Frogs of the genus Thoropa comprise six endemic Brazilian species on the Eastern side of the country. Little is known about their natural history, especially about their acoustic communication. Therefore, aiming to provide an overview of their vocalizations, we analyzed and redescribed male advertisement calls of three living and two possibly extinct species. The smaller species, T. petropolitana and T. lutzi, produce simple calls (one single note) with a higher frequency range than the remaining larger ones. On the other hand, the larger species present complex calls, with more than one note: T. megatympanum calls have three notes, T. taophora calls have four notes, and T. miliaris calls varies from three to six notes. Population snout-vent length negatively correlated with peak of dominant frequency as expected. However, highlighted differences between two populations of T. lutzi, which could indicate need of further taxonomic evaluation of those lineages. Peculiar morphology, such as the absence of vocal sacs and slits, may have contributed to their call variation and highly banded frequency structure. If the observed population differences reflect species-level differences, T. lutzi may be classified as a critically endangered species, as T. petropolitana. Furthermore, we provided a suggestion to an unusual behavior in frogs: calling with the mouth open in the smaller species of the genus. PMID:27617833

Bilateral increase in expression and concentration of tachykinin in a unilateral rabbit muscle overuse model that leads to myositis

PubMed Central

2013-01-01

Background Tachykinins can have pro-inflammatory as well as healing effects during tissue reorganization and inflammation. Recent studies report an up-regulation in the expression of the substance P (SP)-preferred receptor, the neurokinin-1 receptor, in marked muscle inflammation (myositis). There is, however, only very little information on the expression patterns and levels of tachykinins in this situation. Methods The tachykinin system was analyzed using a rabbit experimental model of muscle overuse, whereby unilateral muscle exercise in combination with electrical stimulation led to muscle derangement and myositis in the triceps surae muscle (experimental length 1–6 weeks). Evaluations were made for both parts of the muscle (soleus and gastrocnemius muscles) in experimental and non-experimental (contralateral) sides. Morphologic evaluation, immunohistochemistry, in situ hybridization and enzyme immunoassay (EIA) analyses were applied. Results Myositis and muscle derangement occurred focally not only in the experimental side but also in the non-experimental side. In the inflammatory areas (focal myositis areas), there were frequent nerve fibers showing tachykinin-like immunoreactivity and which were parts of nerve fascicles and which were freely dispersed in the tissue. Cells in the inflammatory infiltrates showed tachykinin-like immunoreactivity and tachykinin mRNA expression. Specific immunoreactivity and mRNA expression were noted in blood vessel walls of both sides, especially in focally affected areas. With increasing experimental length, we observed an increase in the degree of immunoreactivity in the vessel walls. The EIA analyses showed that the concentration of tachykinin in the tissue on both sides increased in a time-dependent manner. There was a statistical correlation in the concentration of tachykinin and the level of tachykinin immunoreactivity in the blood vessel walls between experimental and non-experimental sides. Conclusions The observations show an up-regulation of the tachykinin system bilaterally during muscle derangement/myositis in response to pronounced unilateral muscle overuse. This up-regulation occurred in inflammatory areas and was related not only to increased tachykinin innervation but also to tachykinin expression in blood vessel walls and inflammatory cells. Importantly, the tachykinin system appears to be an important factor not only ipsilaterally but also contralaterally in these processes. PMID:23587295

Bilateral increase in expression and concentration of tachykinin in a unilateral rabbit muscle overuse model that leads to myositis.

PubMed

Song, Yafeng; Stål, Per S; Yu, Ji-Guo; Forsgren, Sture

2013-04-12

Tachykinins can have pro-inflammatory as well as healing effects during tissue reorganization and inflammation. Recent studies report an up-regulation in the expression of the substance P (SP)-preferred receptor, the neurokinin-1 receptor, in marked muscle inflammation (myositis). There is, however, only very little information on the expression patterns and levels of tachykinins in this situation. The tachykinin system was analyzed using a rabbit experimental model of muscle overuse, whereby unilateral muscle exercise in combination with electrical stimulation led to muscle derangement and myositis in the triceps surae muscle (experimental length 1-6 weeks). Evaluations were made for both parts of the muscle (soleus and gastrocnemius muscles) in experimental and non-experimental (contralateral) sides. Morphologic evaluation, immunohistochemistry, in situ hybridization and enzyme immunoassay (EIA) analyses were applied. Myositis and muscle derangement occurred focally not only in the experimental side but also in the non-experimental side. In the inflammatory areas (focal myositis areas), there were frequent nerve fibers showing tachykinin-like immunoreactivity and which were parts of nerve fascicles and which were freely dispersed in the tissue. Cells in the inflammatory infiltrates showed tachykinin-like immunoreactivity and tachykinin mRNA expression. Specific immunoreactivity and mRNA expression were noted in blood vessel walls of both sides, especially in focally affected areas. With increasing experimental length, we observed an increase in the degree of immunoreactivity in the vessel walls. The EIA analyses showed that the concentration of tachykinin in the tissue on both sides increased in a time-dependent manner. There was a statistical correlation in the concentration of tachykinin and the level of tachykinin immunoreactivity in the blood vessel walls between experimental and non-experimental sides. The observations show an up-regulation of the tachykinin system bilaterally during muscle derangement/myositis in response to pronounced unilateral muscle overuse. This up-regulation occurred in inflammatory areas and was related not only to increased tachykinin innervation but also to tachykinin expression in blood vessel walls and inflammatory cells. Importantly, the tachykinin system appears to be an important factor not only ipsilaterally but also contralaterally in these processes.

A unified frame of predicting side effects of drugs by using linear neighborhood similarity.

PubMed

Zhang, Wen; Yue, Xiang; Liu, Feng; Chen, Yanlin; Tu, Shikui; Zhang, Xining

2017-12-14

Drug side effects are one of main concerns in the drug discovery, which gains wide attentions. Investigating drug side effects is of great importance, and the computational prediction can help to guide wet experiments. As far as we known, a great number of computational methods have been proposed for the side effect predictions. The assumption that similar drugs may induce same side effects is usually employed for modeling, and how to calculate the drug-drug similarity is critical in the side effect predictions. In this paper, we present a novel measure of drug-drug similarity named "linear neighborhood similarity", which is calculated in a drug feature space by exploring linear neighborhood relationship. Then, we transfer the similarity from the feature space into the side effect space, and predict drug side effects by propagating known side effect information through a similarity-based graph. Under a unified frame based on the linear neighborhood similarity, we propose method "LNSM" and its extension "LNSM-SMI" to predict side effects of new drugs, and propose the method "LNSM-MSE" to predict unobserved side effect of approved drugs. We evaluate the performances of LNSM and LNSM-SMI in predicting side effects of new drugs, and evaluate the performances of LNSM-MSE in predicting missing side effects of approved drugs. The results demonstrate that the linear neighborhood similarity can improve the performances of side effect prediction, and the linear neighborhood similarity-based methods can outperform existing side effect prediction methods. More importantly, the proposed methods can predict side effects of new drugs as well as unobserved side effects of approved drugs under a unified frame.

Drug side effect extraction from clinical narratives of psychiatry and psychology patients

PubMed Central

Kocher, Jean-Pierre A; Chute, Christopher G; Savova, Guergana K

2011-01-01

Objective To extract physician-asserted drug side effects from electronic medical record clinical narratives. Materials and methods Pattern matching rules were manually developed through examining keywords and expression patterns of side effects to discover an individual side effect and causative drug relationship. A combination of machine learning (C4.5) using side effect keyword features and pattern matching rules was used to extract sentences that contain side effect and causative drug pairs, enabling the system to discover most side effect occurrences. Our system was implemented as a module within the clinical Text Analysis and Knowledge Extraction System. Results The system was tested in the domain of psychiatry and psychology. The rule-based system extracting side effects and causative drugs produced an F score of 0.80 (0.55 excluding allergy section). The hybrid system identifying side effect sentences had an F score of 0.75 (0.56 excluding allergy section) but covered more side effect and causative drug pairs than individual side effect extraction. Discussion The rule-based system was able to identify most side effects expressed by clear indication words. More sophisticated semantic processing is required to handle complex side effect descriptions in the narrative. We demonstrated that our system can be trained to identify sentences with complex side effect descriptions that can be submitted to a human expert for further abstraction. Conclusion Our system was able to extract most physician-asserted drug side effects. It can be used in either an automated mode for side effect extraction or semi-automated mode to identify side effect sentences that can significantly simplify abstraction by a human expert. PMID:21946242

What matters when judging intentionality-moral content or normative status? Testing the rational scientist model of the side-effect.

PubMed

Papadopoulos, C; Hayes, B K

2018-06-01

Previous work has demonstrated a "side-effect effect," such that intentionality is more likely to be attributed to agents who bring about negatively valenced as opposed to positively valenced side effects. The rational-scientist model explains this by suggesting that norm-violating side effects are more informative for inferring intentionality than norm-conforming side effects. In the present study we reexamined this account, addressing limitations of previous empirical tests (e.g., Uttich & Lombrozo, Cognition 116: 87-100, 2010). Side-effect valence and norm status were manipulated factorially, enabling an examination of the impact of norm status on intentionality judgments in both positively and negatively valenced side effects. Additionally, the impact of side-effect norm status on the perceived valences of side effects and agents was examined. Effects of norm status were found for both positive and negative side effects. Violation of an ostensibly neutral norm led to negative perceptions of the side effect. However, a norm status effect on intentionality judgments persisted when these effects were controlled. These results support the view that the side-effect effect is the result of the rational use of social-cognitive evidence.

Incidence and severity of self-reported chemotherapy side effects in routine care: A prospective cohort study

PubMed Central

Haas, Marion; Viney, Rosalie; Pearson, Sallie-Anne; Haywood, Philip; Brown, Chris; Ward, Robyn

2017-01-01

Aim Chemotherapy side effects are often reported in clinical trials; however, there is little evidence about their incidence in routine clinical care. The objective of this study was to describe the frequency and severity of patient-reported chemotherapy side effects in routine care across treatment centres in Australia. Methods We conducted a prospective cohort study of individuals with breast, lung or colorectal cancer undergoing chemotherapy. Side effects were identified by patient self-report. The frequency, prevalence and incidence rates of side effects were calculated by cancer type and grade, and cumulative incidence curves for each side effect computed. Frequencies of side effects were compared between demographic subgroups using chi-squared statistics. Results Side effect data were available for 449 eligible individuals, who had a median follow-up of 5.64 months. 86% of participants reported at least one side effect during the study period and 27% reported a grade IV side effect, most commonly fatigue or dyspnoea. Fatigue was the most common side effect overall (85%), followed by diarrhoea (74%) and constipation (74%). Prevalence and incidence rates were similar across side effects and cancer types. Age was the only demographic factor associated with the incidence of side effects, with older people less likely to report side effects. Conclusion This research has produced the first Australian estimates of self-reported incidence of chemotherapy side effects in routine clinical care. Chemotherapy side effects in routine care are common, continue throughout chemotherapy and can be serious. This work confirms the importance of observational data in providing clinical practice-relevant information to decision-makers. PMID:29016607

Incidence and severity of self-reported chemotherapy side effects in routine care: A prospective cohort study.

PubMed

Pearce, Alison; Haas, Marion; Viney, Rosalie; Pearson, Sallie-Anne; Haywood, Philip; Brown, Chris; Ward, Robyn

2017-01-01

Chemotherapy side effects are often reported in clinical trials; however, there is little evidence about their incidence in routine clinical care. The objective of this study was to describe the frequency and severity of patient-reported chemotherapy side effects in routine care across treatment centres in Australia. We conducted a prospective cohort study of individuals with breast, lung or colorectal cancer undergoing chemotherapy. Side effects were identified by patient self-report. The frequency, prevalence and incidence rates of side effects were calculated by cancer type and grade, and cumulative incidence curves for each side effect computed. Frequencies of side effects were compared between demographic subgroups using chi-squared statistics. Side effect data were available for 449 eligible individuals, who had a median follow-up of 5.64 months. 86% of participants reported at least one side effect during the study period and 27% reported a grade IV side effect, most commonly fatigue or dyspnoea. Fatigue was the most common side effect overall (85%), followed by diarrhoea (74%) and constipation (74%). Prevalence and incidence rates were similar across side effects and cancer types. Age was the only demographic factor associated with the incidence of side effects, with older people less likely to report side effects. This research has produced the first Australian estimates of self-reported incidence of chemotherapy side effects in routine clinical care. Chemotherapy side effects in routine care are common, continue throughout chemotherapy and can be serious. This work confirms the importance of observational data in providing clinical practice-relevant information to decision-makers.

[Comparisons of efficacy and safety of levetiracetam versus phenytoin for seizure prophylaxis in patients with brain injury: a meta analysis].

PubMed

Li, J N; Chen, Y M

2016-10-25

Objective: To systematically review the efficacy, side effects and case-fatality rate of levetiracetam (LEV) versus phenytoin (PHT) for seizure prophylaxis of brain injured patients. Methods: Randomized controlled trials of high quality about LEV versus PHT in seizure prophylaxis of brain injured patients from 2000 to 2016 were collected according to the key word PHT, LEV, brain injury in PubMed, Medline, Ovid, Springer, CNKI, Wanfang data and so on. Valid data were extracted to conduct meta-analysis by RevMan 5.3 software according to inclusion and exclusion criteria. Results: A total of 13 English articles were finally included with 2 529 patients in total.Meta-analysis showed that no significant differences were observed in LEV versus PHT at preventing the occurrence of seizures ( RR =0.88, 95% CI : 0.61-1.27). No superiority of either drug at preventing early seizures ( RR =0.74, 95% CI : 0.42-1.27). As to the occurrence of late seizures, the differences of the two drugs were not statistically significant ( RR =0.71, 95% CI : 0.43-1.20). Number of patients with side effect was not statistically significantly different between the two groups ( RR =0.73, 95% CI : 0.48-1.11). But significant difference was found between LEV and PHT in discontinuation because of side effect ( RR =0.11, 95% CI : 0.06-0.23); no significant differences were noted in the case-fatality rate of patients received pretreatment between the two drugs ( RR =1.57, 95% CI : 0.92-2.67). There were no significant differences between the two groups in the length of stay ( WMD =-1.03, 95% CI : -4.97-2.91). Conclusions: LEV and PHT demonstrate equal efficacy in seizure prevention after brain injury. The differences are insignificant in the side effect, the case-fatality rate and the length of stay between LEV and PH treatment, but adverse drug reactions requiring change in therapy occur more in PHT. Phenytoin remains the first choice for seizure prevention after brain injury based on the existing evidence, while levetiracetam seems to be a favorable choice where there is risk of drug-drug interactions and drug toxicity. However, very few randomized controlled trials on this topic were found, and larger prospective trials are warranted.

Evidence-based clinical update: Which local anesthetic drug for pediatric caudal block provides optimal efficacy with the fewest side effects?

PubMed

Dobereiner, Elisabeth F A; Cox, Robin G; Ewen, Alastair; Lardner, David R

2010-12-01

The purpose of this evidence-based clinical update is to identify the best evidence when selecting a long-acting local anesthetic agent for single-shot pediatric caudal anesthesia in children. A structured literature search was conducted using PubMed and Medline (OVID) using the terms "caudal" and combinations of at least two of "bupivacaine", "ropivacaine", and "levobupivacaine". The search limits included "randomized controlled trials" (RCTs), "meta-analysis", "evidence-based reviews" or "reviews", "human", and "all child: 0-18 yr". Seventeen RCTs were identified that concerned single-shot pediatric caudal anesthesia with at least two of the three drugs in question. Data were extracted for the areas of clinical efficacy and side effects. Study findings were assigned levels of evidence, and grades of recommendation were made according to Centre for Evidence-Based Medicine criteria. The three drugs investigated were found to be equivalent in terms of efficacy. Evidence showed bupivacaine with the highest incidence of motor block and ropivacaine with the lowest. Adverse effects were rare and unrelated to the choice of drug. There were no serious adverse events. None of the three agents was shown to be superior in terms of efficacy. Bupivacaine is preferred if motor block is desired, ropivacaine is preferred if motor block is to be minimized. Adverse effects in human studies are rare, mild, and unrelated to the choice of drug. Despite encountering the absence of serious adverse events in each of the studies reviewed, it is noted that animal studies suggest a safer profile with ropivacaine or levobupivacaine than with bupivacaine.

Real-Time Dynamic Model Learning and Adaptation for Underwater Vehicles

DTIC Science & Technology

2013-09-01

LHr f AS FS LHr f α α α α α α α α = − + − + − + − + (9) Note: For ease of notation s● = sin(●), c●=cos(●), and t●=tan(●). LV, LH1, and LH2 are...propellers of the aft or forward pair, and LH2 is defined as the distance between the centroid of the propellers of the right or left side pair

Differential-Game Examination of Optimal Time-Sequential Fire-Support Strategies

DTIC Science & Technology

1976-09-01

77 004033 NPS-55Tw76091 NAVAL POSTGRADUATE SCHOOL 4Monterey, California i ’ DIFFERENTIAL- GAME EXAMINATION OF OPTIMAL TIME-SEQUENTIAL FIRE...CATALOG NUMBER NPS-55Tw76091 4. TITLE (and Subtitle) S. TYPE OF REPDRT & PERIOD COVERED Differential- Game Examination of Optimal Tir Technical Report...NOTES 19. KEY WORDS (Continue on reverse side If necessary and identify by block number) Differential Games Lanchester Theory of Combat Military Tactics

Certified Reduced Basis Model Characterization: a Frequentistic Uncertainty Framework

DTIC Science & Technology

2011-01-11

14) It then follows that the Legendre coefficient random vector, (Z [0], Z [1], . . . , Z [I])(ω), is (I+1)– variate normally distributed with mean (δ...I. Note each two-sided inequality represents two constraints. 3. PDE-Based Statistical Inference We now proceed to the parametrized partial...appearance of defects or geometric variations relative to an initial baseline, or perhaps manufacturing departures from nominal specifications; if our

Thermo-physics technical note No. 37: SNAP- 10A, Stainless Steel-316 vessel wall ablation. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Montgomery, L.D.

1964-12-07

The altitudes and times of ablation have been determined for the SNAP-10A, SS-316 vessel wall reentering under various conditions. The results are confined to one typical location on the reactor and to one typical reentry trajectory. The location is the side wall of the vessel and the trajectory is the one used in NAA-SR-8303.

STS-44 Mission Specialist (MS) Runco floats on OV-104's middeck

NASA Technical Reports Server (NTRS)

1991-01-01

STS-44 Mission Specialist (MS) Mario Runco, Jr, wearing communications kit assembly headset (HDST), freefloats on the middeck of Atlantis, Orbiter Vehicle (OV) 104. HDST interface unit (HIU) is strapped to Runco's thigh. Note that his back is against the middeck ceiling, his feet at the port side wall, and his left hand at the forward lockers. Runco is also wearing a United States Navy t-shirt.

Conference summary: Biodiversity and management of the Madrean Archipelago III: Closing remarks and notes from the concluding session

Treesearch

Dale S. Turner; Alejandro Castellanos

2013-01-01

During the first week of May 2012, the Third Conference on Biodiversity and Management of the Madrean Archipelago brought together more than 300 people with an interest in this region. It included scientists, land managers, activists, and land owners from both sides of the international border. After three and a half days of presentations, the participants gathered for...

View forward from bulkhead no. 38 of compartment B126 crew ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View forward from bulkhead no. 38 of compartment B-126 crew space. Note stop valves on bulkhead at right side of photograph; these steam control valves allowed remote activation of the main, auxiliary and safety valves for the port engine in the event that the engine room valves were disabled or unreachable. (044) - USS Olympia, Penn's Landing, 211 South Columbus Boulevard, Philadelphia, Philadelphia County, PA

Advanced Diagnostics and Instrumentation for Chemically Reactive Flow Systems.

DTIC Science & Technology

1981-09-01

graphic images from our model programs on the color display unit. We have written software for axial tomography image reconstruction that will be...technique for such applications . It can be shown that by making measurements, as described above, simultaneously at two wavelengths, one can derive a...DISTRIBUTION STATEMENT (of the abstract entered In Block 20, it different from Report) IS. SUPPLEMENTARY NOTES 19. KEY WORDS (Continue on reverse side it

International Competencies for the Defense Acquisition Workforce

DTIC Science & Technology

2010-08-01

subsets of “multi- or cross-cultural knowledge, foreign policy, protocol and etiquette , and ambiguity of ex- pectations.” With those definitions serving...poll went on to add that 68 percent wanted to increase their knowledge on cross-cultural sensi- tivities, 50 percent on international protocol and... etiquette , and 54 percent on developing international negotiation skills. On the demand side, noted journalist Roxana Tiron of The- Hill.com reported

Review and Process Effects of Spontaneous Note-Taking on Text Comprehension.

PubMed

Slotte; Lonka

1999-01-01

This study examines how quantitative and qualitative differences in spontaneously taken notes are related to text comprehension in combination with reviewing or not reviewing previously made notes. High school graduates (N = 226) were allowed to take notes in any way they desired while reading a philosophical text. Approximately half the participants were told that they could review their notes during writing tasks designed to measure the ability to define, compare, and evaluate text content. The other half of the participants answered the subsequent questions without their notes. The process of taking notes was rated on the basis of note quality and quantity. The results revealed significant review and process effects in spontaneous note-taking. Reviewing the notes during essay-writing generally resulted in good performance in an exam calling for deep-level text comprehension. However, this review effect was mainly limited to detailed learning instead of making one's own inferences. Results pertaining to note quality indicated that the participants who summarized the content of the text resulted in better performance in all tasks in comparison with those who produced notes following the text order or verbatim notes. The amount of note-taking was also positively related to text comprehension. The discussion focuses upon the situational appropriateness of note-taking effects that pose challenges to educators. Copyright 1999 Academic Press.

Sudden onset unilateral sensorineural hearing loss after rabies vaccination.

PubMed

Okhovat, Saleh; Fox, Richard; Magill, Jennifer; Narula, Antony

2015-12-15

A 33-year-old man developed profound sudden onset right-sided hearing loss with tinnitus and vertigo, within 24 h of pretravel rabies vaccination. There was no history of upper respiratory tract infection, systemic illness, ototoxic medication or trauma, and normal otoscopic examination. Pure tone audiograms (PTA) demonstrated right-sided sensorineural hearing loss (thresholds 90-100 dB) and normal left-sided hearing. MRI internal acoustic meatus, viral serology (hepatitis B, C, HIV and cytomegalovirus) and syphilis screen were normal. Positive Epstein-Barr virus IgG, viral capsid IgG and anticochlear antibodies (anti-HSP-70) were noted. Initial treatment involved a course of high-dose oral prednisolone and acyclovir. Repeat PTAs after 12 days of treatment showed a small improvement in hearing thresholds. Salvage intratympanic steroid injections were attempted but failed to improve hearing further. Sudden onset sensorineural hearing loss (SSNHL) is an uncommon but frightening experience for patients. This is the first report of SSNHL following rabies immunisation in an adult. 2015 BMJ Publishing Group Ltd.

Side effects associated with anti-HIV drugs.

PubMed

Highleyman, L

1998-04-01

Many side effects are associated with the use of anti-HIV drugs, impacting the development of drug resistance and the quality of life for HIV-patients. Concern about side effects is a primary factor in deterring people from beginning HIV therapy. Frequency and severity of side effects vary greatly, but they are frequently more common and severe in people who are taking a new drug or who have advanced HIV disease. Information on side effects comes largely from clinical trials; however, many side effects are not discovered until the drug has been approved and used by larger numbers of people. Side effects vary from serious toxicities that require stopping treatment to uncomfortable or annoying side effects that interfere with daily life. A table categorizes the four major side effects (nausea, fever, skin rash, and fatigue) and divides them into grades that describe their intensity. A chart lists the side effects associated with specific anti-HIV drugs. Suggestions for managing side effects are included.

Effects of Note-Taking Instruction and Note-Taking Languages on College EFL Students' Listening Comprehension

ERIC Educational Resources Information Center

Tsai-Fu, Tsai; Wu, Yongan

2010-01-01

Background: The effect of note-taking has been well-recognized by EFL educators. However, little empirical research has been done to investigate combined effects of note-taking instruction and note-taking language (whether in L1 or L2) in an acquisition-poor environment, where English is used as an instructional language yet the audience is…

Side Effect Perceptions and Their Impact on Treatment Decisions in Women.

PubMed

Waters, Erika A; Pachur, Thorsten; Colditz, Graham A

2017-04-01

Side effects prompt some patients to forego otherwise-beneficial therapies. This study explored which characteristics make side effects particularly aversive. We used a psychometric approach, originating from research on risk perception, to identify the factors (or components) underlying side effect perceptions. Women ( N = 149) aged 40 to 74 years were recruited from a patient registry to complete an online experiment. Participants were presented with hypothetical scenarios in which an effective and necessary medication conferred a small risk of a single side effect (e.g., nausea, dizziness). They rated a broad range of side effects on several characteristics (e.g., embarrassing, treatable). In addition, we collected 4 measures of aversiveness for each side effect: choosing to take the medication, willingness to pay to avoid the side effect (WTP), negative affective attitude associated with the side effect, and how each side effect ranks among others in terms of undesirability. A principal components analysis (PCA) was used to identify the components underlying side effect perceptions. Then, for each aversiveness measure separately, regression analyses were used to determine which components predicted differences in aversiveness among the side effects. The PCA revealed 4 components underlying side effect perceptions: affective challenge (e.g., frightening), social challenge (e.g., disfiguring), physical challenge (e.g., painful), and familiarity (e.g., common). Side effects perceived as affectively and physically challenging elicited the highest levels of aversiveness across all 4 measures. Understanding what side effect characteristics are most aversive may inform interventions to improve medical decisions and facilitate the translation of novel biomedical therapies into clinical practice.