Dental rehabilitation using an implant-carrying plate system in a severely resorbed edentulous maxilla: a case report.

PubMed

Kurita, Hiroshi; Sakai, Hironori; Uehara, Shinobu; Kurashina, Kenji

2008-01-01

This clinical article describes a case of dental rehabilitation using an implant-carrying plate system (EPITEC) for a patient with severely resorbed edentulous maxilla and microstomia. In this case, the presence of microstomia prevented bone augmentation procedures through an intraoral approach. Treatment using 2 endosseous implants inserted in the canine regions and an implant-supported overdenture was planned. However, endosseous implants were not feasible on the right side because of insufficient available bone volume. An implant-carrying plate system was then utilized on the right side. Four months later, an implant-supported ball-attachment overdenture was fabricated. At the 2-year follow-up, the clinical course remained uneventful, and the patient remained satisfied with the treatment.

Port side view of the Orbiter Discovery from an elevated ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Port side view of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the ground support hardware known as Strongbacks attached to the payload bay doors, the crew access hatch below the name Discovery on the forward section of the Orbiter and the removed Orbiter Maneuvering System/Reaction Control System pod from the aft (tai) section. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Client-Side Data Processing and Training for Multispectral Imagery Applications in the GOES-R Era

NASA Technical Reports Server (NTRS)

Fuell, Kevin; Gravelle, Chad; Burks, Jason; Berndt, Emily; Schultz, Lori; Molthan, Andrew; Leroy, Anita

2016-01-01

RGB imagery can be created locally (i.e. client-side) from single band imagery already on the system with little impact given recommended change to texture cache in AWIPS II. Training/Reference material accessible to forecasters within their operational display system improves RGB interpretation and application as demonstrated at OPG. Application examples from experienced forecasters are needed to support the larger community use of RGB imagery and these can be integrated into the user's display system.

GraphSAW: a web-based system for graphical analysis of drug interactions and side effects using pharmaceutical and molecular data.

PubMed

Shoshi, Alban; Hoppe, Tobias; Kormeier, Benjamin; Ogultarhan, Venus; Hofestädt, Ralf

2015-02-28

Adverse drug reactions are one of the most common causes of death in industrialized Western countries. Nowadays, empirical data from clinical studies for the approval and monitoring of drugs and molecular databases is available. The integration of database information is a promising method for providing well-based knowledge to avoid adverse drug reactions. This paper presents our web-based decision support system GraphSAW which analyzes and evaluates drug interactions and side effects based on data from two commercial and two freely available molecular databases. The system is able to analyze single and combined drug-drug interactions, drug-molecule interactions as well as single and cumulative side effects. In addition, it allows exploring associative networks of drugs, molecules, metabolic pathways, and diseases in an intuitive way. The molecular medication analysis includes the capabilities of the upper features. A statistical evaluation of the integrated data and top 20 drugs concerning drug interactions and side effects is performed. The results of the data analysis give an overview of all theoretically possible drug interactions and side effects. The evaluation shows a mismatch between pharmaceutical and molecular databases. The concordance of drug interactions was about 12% and 9% of drug side effects. An application case with prescribed data of 11 patients is presented in order to demonstrate the functionality of the system under real conditions. For each patient at least two interactions occured in every medication and about 8% of total diseases were possibly induced by drug therapy. GraphSAW (http://tunicata.techfak.uni-bielefeld.de/graphsaw/) is meant to be a web-based system for health professionals and researchers. GraphSAW provides comprehensive drug-related knowledge and an improved medication analysis which may support efforts to reduce the risk of medication errors and numerous drastic side effects.

Use of New Commercial, Off-the-Shelf, High-Definition Structure Scanning Fathometer/Depth Finder For Coastal Current Survey Operations

NASA Astrophysics Data System (ADS)

Roggenstein, E. B.; Gray, G.

2013-12-01

The National Oceanic and Atmospheric Administration (NOAA) National Ocean Service (NOS) Center for Operational Oceanographic Products and Services (COOPS) manages three national observing system programs. These are the National Water level Observation Network (NWLON) (210 stations), the 23 NOAA/Physical Oceanographic Real-Time Systems (PORTS), and National Currents Observing Program (NCOP) (approximately 70 deployments/year). In support of its mission COOPS operates and maintains a number of small boats. During vessel operations, side-scan sonar data are at times needed to provide information about bottom structure for future work in the area. For example, potential hazards, obstructions, or bottom morphology features that have not been identified on localized charts for a given area could be used to inform decisions on planned installations. Side-scan sonar capability is also important when attempting to reacquire bottom mounts that fail to surface at the conclusion of a current meter survey. Structure mapping and side-scan capabilities have been added to recent consumer-level, commercial, off-the-shelf fathometers, generally intended for recreational, commercial fishing, and diving applications. We are proposing to investigate these systems' viability for meeting survey requirements. We assess their ability to provide a flexible alternative to research/commercial oceanographic level side-scan system at a significant cost savings. Such systems could provide important information to support scientific missions that require qualitative seafloor imagery.

An Environment for Guideline-based Decision Support Systems for Outpatients Monitoring.

PubMed

Zini, Elisa M; Lanzola, Giordano; Bossi, Paolo; Quaglini, Silvana

2017-08-11

We propose an architecture for monitoring outpatients that relies on mobile technologies for acquiring data. The goal is to better control the onset of possible side effects between the scheduled visits at the clinic. We analyze the architectural components required to ensure a high level of abstraction from data. Clinical practice guidelines were formalized with Alium, an authoring tool based on the PROforma language, using SNOMED-CT as a terminology standard. The Alium engine is accessible through a set of APIs that may be leveraged for implementing an application based on standard web technologies to be used by doctors at the clinic. Data sent by patients using mobile devices need to be complemented with those already available in the Electronic Health Record to generate personalized recommendations. Thus a middleware pursuing data abstraction is required. To comply with current standards, we adopted the HL7 Virtual Medical Record for Clinical Decision Support Logical Model, Release 2. The developed architecture for monitoring outpatients includes: (1) a guideline-based Decision Support System accessible through a web application that helps the doctors with prevention, diagnosis and treatment of therapy side effects; (2) an application for mobile devices, which allows patients to regularly send data to the clinic. In order to tailor the monitoring procedures to the specific patient, the Decision Support System also helps physicians with the configuration of the mobile application, suggesting the data to be collected and the associated collection frequency that may change over time, according to the individual patient's conditions. A proof of concept has been developed with a system for monitoring the side effects of chemo-radiotherapy in head and neck cancer patients. Our environment introduces two main innovation elements with respect to similar works available in the literature. First, in order to meet the specific patients' needs, in our work the Decision Support System also helps the physicians in properly configuring the mobile application. Then the Decision Support System is also continuously fed by patient-reported outcomes.

Detail view of the forward section, port side, of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view of the forward section, port side, of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the removal of the Forward Reaction Control System Module from the nose section, the ground-support window covers and the strongback attached to the payload bay door. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Strain of implants depending on occlusion types in mandibular implant-supported fixed prostheses

PubMed Central

Sohn, Byoung-Sup; Heo, Seong-Joo; Koak, Jai-Young; Kim, Seong-Kyun

2011-01-01

PURPOSE This study investigated the strain of implants using a chewing simulator with strain gauges in mandibular implant-supported fixed prostheses under various dynamic loads. MATERIALS AND METHODS Three implant-supported 5-unit fixed prostheses were fabricated with three different occlusion types (Group I: Canine protected occlusion, Group II: Unilaterally balanced occlusion, Group III: Bilaterally balanced occlusion). Two strain gauges were attached to each implant abutment. The programmed dynamic loads (0 - 300 N) were applied using a chewing simulator (MTS 858 Mini Bionix II systems, MTS systems corp., Minn, USA) and the strains were monitored. The statistical analyses were performed using the paired t-test and the ANOVA. RESULTS The mean strain values (MSV) for the working sides were 151.83 µε, 176.23 µε, and 131.07 µε for Group I, Group II, and Group III, respectively. There was a significant difference between Group II and Group III (P < .05). Also, the MSV for non-working side were 58.29 µε, 72.64 µε, and 98.93 µε for Group I, Group II, and Group III, respectively. One was significantly different from the others with a 95% confidence interval (P < .05). CONCLUSION The MSV for the working side of Groups I and II were significantly different from that for the non-working side (Group I: t = 7.58, Group II: t = 6.25). The MSV for the working side of Group II showed significantly larger than that of Group III (P < .01). Lastly, the MSV for the non-working side of Group III showed significantly larger than those of Group I or Group II (P < .01). PMID:21503186

On the ability of synchronously rotating planets to support atmospheres

NASA Astrophysics Data System (ADS)

Joshi, Manoj M.; Haberle, Robert M.

1997-01-01

Planets within the habitable zones of M stars are likely to be synchronous rotators, i.e., one side is permanently illuminated while the other side is in perpetual darkness. For such planets to be habitable, horizontal atmospheric motions must be capable of transporting enough heat from the day side to the night side to prevent the atmosphere from freezing out. Simple calculations have shown that the equivalent of approximately 150 mb of CO2 is required to prevent atmospheric condensation on the dark side. We now use a 3D global circulation model in order to better assess the ability of these planets to sustain an atmosphere. The results of this work show that for an Earth-sized planet, 100 mb of CO2 is required to support an atmosphere, while 1-2 bars are sufficient to allow liquid water everywhere. Planetary systems associated with M stars should therefore not be ruled out in the search for life in the universe.

Actuator and electronics packaging for extrinsic humanoid hand

NASA Technical Reports Server (NTRS)

Ihrke, Chris A. (Inventor); Bridgwater, Lyndon (Inventor); Diftler, Myron A. (Inventor); Reich, David M. (Inventor); Askew, Scott R. (Inventor)

2013-01-01

The lower arm assembly for a humanoid robot includes an arm support having a first side and a second side, a plurality of wrist actuators mounted to the first side of the arm support, a plurality of finger actuators mounted to the second side of the arm support and a plurality of electronics also located on the first side of the arm support.

5. HOUSE NORTH END EXTERIOR SHOWING ASBESTOS SIDING, CONCRETE WALKWAY ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. HOUSE NORTH END EXTERIOR SHOWING ASBESTOS SIDING, CONCRETE WALKWAY TO REAR OF HOUSE, CLOSELINE SUPPORT AT EXTREME PHOTO RIGHT, AND CASEMENT WINDOW TO ATTIC JUST BELOW THE GABLE PEAK. VIEW TO SOUTHWEST. - Big Creek Hydroelectric System, Big Creek Town, Operator House, Orchard Avenue south of Huntington Lake Road, Big Creek, Fresno County, CA

Detail view of the aft section, port side, of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view of the aft section, port side, of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the removed Orbiter Maneuvering System/Reaction Control System pod from the base of the vertical stabilizer the strongback ground-support equipment attached to the payload bay door. This view is also a good view of the leading edge and top surface of the Orbiter wing. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Distributed parallel messaging for multiprocessor systems

DOEpatents

Chen, Dong; Heidelberger, Philip; Salapura, Valentina; Senger, Robert M; Steinmacher-Burrow, Burhard; Sugawara, Yutaka

2013-06-04

A method and apparatus for distributed parallel messaging in a parallel computing system. The apparatus includes, at each node of a multiprocessor network, multiple injection messaging engine units and reception messaging engine units, each implementing a DMA engine and each supporting both multiple packet injection into and multiple reception from a network, in parallel. The reception side of the messaging unit (MU) includes a switch interface enabling writing of data of a packet received from the network to the memory system. The transmission side of the messaging unit, includes switch interface for reading from the memory system when injecting packets into the network.

Wavelet Entropy and Directed Acyclic Graph Support Vector Machine for Detection of Patients with Unilateral Hearing Loss in MRI Scanning

PubMed Central

Wang, Shuihua; Yang, Ming; Du, Sidan; Yang, Jiquan; Liu, Bin; Gorriz, Juan M.; Ramírez, Javier; Yuan, Ti-Fei; Zhang, Yudong

2016-01-01

Highlights We develop computer-aided diagnosis system for unilateral hearing loss detection in structural magnetic resonance imaging.Wavelet entropy is introduced to extract image global features from brain images. Directed acyclic graph is employed to endow support vector machine an ability to handle multi-class problems.The developed computer-aided diagnosis system achieves an overall accuracy of 95.1% for this three-class problem of differentiating left-sided and right-sided hearing loss from healthy controls. Aim: Sensorineural hearing loss (SNHL) is correlated to many neurodegenerative disease. Now more and more computer vision based methods are using to detect it in an automatic way. Materials: We have in total 49 subjects, scanned by 3.0T MRI (Siemens Medical Solutions, Erlangen, Germany). The subjects contain 14 patients with right-sided hearing loss (RHL), 15 patients with left-sided hearing loss (LHL), and 20 healthy controls (HC). Method: We treat this as a three-class classification problem: RHL, LHL, and HC. Wavelet entropy (WE) was selected from the magnetic resonance images of each subjects, and then submitted to a directed acyclic graph support vector machine (DAG-SVM). Results: The 10 repetition results of 10-fold cross validation shows 3-level decomposition will yield an overall accuracy of 95.10% for this three-class classification problem, higher than feedforward neural network, decision tree, and naive Bayesian classifier. Conclusions: This computer-aided diagnosis system is promising. We hope this study can attract more computer vision method for detecting hearing loss. PMID:27807415

Wavelet Entropy and Directed Acyclic Graph Support Vector Machine for Detection of Patients with Unilateral Hearing Loss in MRI Scanning.

PubMed

Wang, Shuihua; Yang, Ming; Du, Sidan; Yang, Jiquan; Liu, Bin; Gorriz, Juan M; Ramírez, Javier; Yuan, Ti-Fei; Zhang, Yudong

2016-01-01

Highlights We develop computer-aided diagnosis system for unilateral hearing loss detection in structural magnetic resonance imaging.Wavelet entropy is introduced to extract image global features from brain images. Directed acyclic graph is employed to endow support vector machine an ability to handle multi-class problems.The developed computer-aided diagnosis system achieves an overall accuracy of 95.1% for this three-class problem of differentiating left-sided and right-sided hearing loss from healthy controls. Aim: Sensorineural hearing loss (SNHL) is correlated to many neurodegenerative disease. Now more and more computer vision based methods are using to detect it in an automatic way. Materials: We have in total 49 subjects, scanned by 3.0T MRI (Siemens Medical Solutions, Erlangen, Germany). The subjects contain 14 patients with right-sided hearing loss (RHL), 15 patients with left-sided hearing loss (LHL), and 20 healthy controls (HC). Method: We treat this as a three-class classification problem: RHL, LHL, and HC. Wavelet entropy (WE) was selected from the magnetic resonance images of each subjects, and then submitted to a directed acyclic graph support vector machine (DAG-SVM). Results: The 10 repetition results of 10-fold cross validation shows 3-level decomposition will yield an overall accuracy of 95.10% for this three-class classification problem, higher than feedforward neural network, decision tree, and naive Bayesian classifier. Conclusions: This computer-aided diagnosis system is promising. We hope this study can attract more computer vision method for detecting hearing loss.

STS-31 pre-deployment checkout of the Hubble Space Telescope (HST) on OV-103

NASA Image and Video Library

1990-04-25

During STS-31 checkout, the Hubble Space Telescope (HST) is held in a pre-deployment position by Discovery's, Orbiter Vehicle (OV) 103's, remote manipulator system (RMS). The view, taken from the crew cabin overhead window W7, shows the starboard solar array (SA) panel (center) and two high gain antennae (HGA) (on either side) stowed along side the Support System Module (SSM) forward shell. The sun highlights HST against the blackness of space.

Anti-terrorist vehicle crash impact energy absorbing barrier

DOEpatents

Swahlan, David J.

1989-01-01

An anti-terrorist vehicle crash barrier includes side support structures, crushable energy absorbing aluminum honeycomb modules, and an elongated impact-resistant beam extending between, and at its opposite ends through vertical guideways defined by, the side support structures. An actuating mechanism supports the beam at its opposite ends for movement between a lowered barrier-withdrawn position in which a traffic-supporting side of the beam is aligned with a traffic-bearing surface permitting vehicular traffic between the side support structures and over the beam, and a raised barrier-imposed position in which the beam is aligned with horizontal guideways defined in the side support structures above the traffic-bearing surface, providing an obstruction to vehicular traffic between the side support structures. The beam is movable rearwardly in the horizontal guideways with its opposite ends disposed transversely therethrough upon being impacted at its forward side by an incoming vehicle. The crushable modules are replaceably disposed in the horizontal guideways between aft ends thereof and the beam. The beam, replaceable modules, side support structures and actuating mechanism are separate and detached from one another such that the beam and replaceable modules are capable of coacting to disable and stop an incoming vehicle without causing structural damage to the side support structures and actuating mechanism.

Horizontally opposed trunnion forward engine mount system supported beneath a wing pylon

NASA Technical Reports Server (NTRS)

Seaquist, John D. (Inventor); Culbertson, Chris (Inventor)

2000-01-01

The present invention relates to an engine mount assembly for supporting an aircraft engine in aft-cantilevered position beneath the aircraft wing. The assembly includes a pair forward engine mounts positioned on opposite sides of an integrally formed yoke member wrapped about the upper half of the engine casing. Each side of the yoke is preferably configured as an A-shaped frame member with the bottom portions joining each other and the pylon. To prevent backbone bending of the engine trunnion assembly, the forward engine mounts supported at opposite ends of the yoke engage the casing along its centerline. The trunnion assembly is preferably constructed of high strength titanium machined and/or forged.

Photovoltaic array mounting apparatus, systems, and methods

DOEpatents

West, John Raymond; Atchley, Brian; Hudson, Tyrus Hawkes; Johansen, Emil

2014-12-02

An apparatus for mounting a photovoltaic (PV) module on a surface, including a support with an upper surface, a lower surface, tabs, one or more openings, and a clip comprising an arm and a notch, where the apparatus resists wind forces and seismic forces and creates a grounding electrical bond between the PV module, support, and clip. The invention further includes a method for installing PV modules on a surface that includes arranging supports in rows along an X axis and in columns along a Y axis on a surface such that in each row the distance between two neighboring supports does not exceed the length of the longest side of a PV module and in each column the distance between two neighboring supports does not exceed the length of the shortest side of a PV module.

Space shuttle: High angle of attack transition and low angle of attack launch phase aerodynamic stability and control of GD/C B-18E-2, B-18E-3 delta wing booster, and launch configuration of MSC-040A orbiter and twin pressure fed boosters

NASA Technical Reports Server (NTRS)

Debevoise, J. M.; Mcginnis, R. F.

1972-01-01

The test was a conventional stability and control test except for two aspects. One was the very high angles of attack at which the delta wing configurations were tested (up to 60 degrees) at Mach numbers of 3 and 4.96. The other was the installation of the orbiter and twin boosters in a manner that caused the support system to induce normal forces and side forces on the aft portion of the boosters at all Mach numbers; i.e., the support and the booster bodies were close together, side by side.

Deploying Server-side File System Monitoring at NERSC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uselton, Andrew

2009-05-01

The Franklin Cray XT4 at the NERSC center was equipped with the server-side I/O monitoring infrastructure Cerebro/LMT, which is described here in detail. Insights gained from the data produced include a better understanding of instantaneous data rates during file system testing, file system behavior during regular production time, and long-term average behaviors. Information and insights gleaned from this monitoring support efforts to proactively manage the I/O infrastructure on Franklin. A simple model for I/O transactions is introduced and compared with the 250 million observations sent to the LMT database from August 2008 to February 2009.

Articulated suspension system

NASA Technical Reports Server (NTRS)

Bickler, Donald B. (Inventor)

1989-01-01

The invention provides a rough terrain vehicle which maintains a substantially constant weight, and therefore traction, on all wheels, despite one wheel moving considerably higher or lower than the others, while avoiding a very soft spring suspension. The vehicle includes a chassis or body to be supported and a pair of side suspensions at either side of the body. In a six wheel vehicle, each side suspension includes a middle wheel, and front and rear linkages respectively coupling the front and rear wheels to the middle wheel. A body link pivotally connects the front and rear linkages together, with the middle of the body link rising or falling by only a fraction of the rise or fall of any of the three wheels. The body link pivotally supports the middle of the length of the body. A transverse suspension for suspending the end of the body on the side suspensions includes a middle part pivotally connected to the body about a longitudinal axis and opposite ends each pivotally connected to one of the side suspensions along at least a longitudinal axis.

Dual chamber system providing simultaneous etch and deposition on opposing substrate sides for growing low defect density epitaxial layers

DOEpatents

Kulkarni, Nagraj S [Knoxville, TN; Kasica, Richard J. ,

2011-03-08

A dual-chamber reactor can include a housing enclosing a volume having a divider therein, where the divider defines a first chamber and a second chamber. The divider can include a substrate holder that supports at least one substrate and exposes a first side of the substrate to the first chamber and a second side of the substrate to the second chamber. The first chamber can include an inlet for delivering at least one reagent to the first chamber for forming a film on the first side of the substrate, and the second chamber can include a removal device for removing material from the second side of the substrate.

Research on Simulation Requirements and Business Architecture of Automated Demand Response in Power Sales Side Market Liberalization

NASA Astrophysics Data System (ADS)

Liu, Yiqun; Zhou, Pengcheng; Zeng, Ming; Chen, Songsong

2018-01-01

With the gradual reform of the electricity market, the power sale side liberalization has become the focus of attention as the key task of reform. The open power market provides a good environment for DR (Demand Response). It is of great significance to research the simulation requirements and business architecture of ADR (Automatic Demand Response) in power sale side market liberalization. Firstly, this paper analyzes the simulation requirements of ADR. Secondly, it analyzes the influence factors that the business development of ADR from five aspects after power sale side market liberalization. Finally, Based on ADR technology support system, the business architecture of ADR after power sale side market liberalization is constructed.

30 CFR 75.215 - Longwall mining systems.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Longwall mining systems. 75.215 Section 75.215... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.215 Longwall mining systems. For each... a safe travelway out of the section through the tailgate side of the longwall; and (b) The...

30 CFR 75.215 - Longwall mining systems.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Longwall mining systems. 75.215 Section 75.215... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.215 Longwall mining systems. For each... a safe travelway out of the section through the tailgate side of the longwall; and (b) The...

30 CFR 75.215 - Longwall mining systems.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Longwall mining systems. 75.215 Section 75.215... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.215 Longwall mining systems. For each... a safe travelway out of the section through the tailgate side of the longwall; and (b) The...

Furfural formation from the pre-hydrolysis liquor of a hardwood kraft-based dissolving pulp production process.

PubMed

Liu, Haitang; Hu, Huiren; Jahan, M Sarwar; Ni, Yonghao

2013-03-01

This study aimed to produce furfural from the PHL. Results showed best furfural yield of 32.8% and the furfural selectivity of 37.7% in the monophase system (170 °C, 100 min), while they were 60.1% and 69.8%, respectively in the biphase system. The lower furfural selectivity in the monophase system was explained by more side reactions, such as fragmentation, condensation reactions, resinification and others. Model compounds such as: xylose, furfural, syringaldehyde, were used to confirm/identify these side reactions. The addition of dilute sulfuric acid/acetic acid in the system under the same conditions decreased the recovery of furfural. The addition of syringaldehyde into the PHL also led to a decrease in the furfural yield, supporting the conclusion that lignin structures in the PHL may also be involved in the side reactions, thus decreasing the furfural yield. Copyright © 2012 Elsevier Ltd. All rights reserved.

Space ultra-vacuum facility and method of operation

NASA Technical Reports Server (NTRS)

Naumann, Robert J. (Inventor)

1986-01-01

A wake shield facility providing an ultrahigh vacuum level for space processing is described. The facility is in the shape of a truncated, hollow hemispherical section, one side of the shield convex and the other concave. The shield surface is preferably made of material that has low out-gassing characteristics such as stainless steel. A material sample supporting fixture in the form of a carousel is disposed on the convex side of the shield at its apex. Movable arms, also on the convex side, are connected by the shield in proximity to the carousel, the arms supporting processing fixtures, and providing for movement of the fixtures to predetermined locations required for producing interations with material samples. For MBE processes a vapor jet projects a stream of vaporized material onto a sample surface. The fixtures are oriented to face the surface of the sample being processed when in their extended position, and when not in use they are retractable to a storage position. The concave side of the shield has a support structure including metal struts connected to the shield, extending radially inward. The struts are joined to an end plate disposed parallel to the outer edge of the shield. This system eliminates outgassing contamination.

Hydrogen separation process

DOEpatents

Mundschau, Michael [Longmont, CO; Xie, Xiaobing [Foster City, CA; Evenson, IV, Carl; Grimmer, Paul [Longmont, CO; Wright, Harold [Longmont, CO

2011-05-24

A method for separating a hydrogen-rich product stream from a feed stream comprising hydrogen and at least one carbon-containing gas, comprising feeding the feed stream, at an inlet pressure greater than atmospheric pressure and a temperature greater than 200.degree. C., to a hydrogen separation membrane system comprising a membrane that is selectively permeable to hydrogen, and producing a hydrogen-rich permeate product stream on the permeate side of the membrane and a carbon dioxide-rich product raffinate stream on the raffinate side of the membrane. A method for separating a hydrogen-rich product stream from a feed stream comprising hydrogen and at least one carbon-containing gas, comprising feeding the feed stream, at an inlet pressure greater than atmospheric pressure and a temperature greater than 200.degree. C., to an integrated water gas shift/hydrogen separation membrane system wherein the hydrogen separation membrane system comprises a membrane that is selectively permeable to hydrogen, and producing a hydrogen-rich permeate product stream on the permeate side of the membrane and a carbon dioxide-rich product raffinate stream on the raffinate side of the membrane. A method for pretreating a membrane, comprising: heating the membrane to a desired operating temperature and desired feed pressure in a flow of inert gas for a sufficient time to cause the membrane to mechanically deform; decreasing the feed pressure to approximately ambient pressure; and optionally, flowing an oxidizing agent across the membrane before, during, or after deformation of the membrane. A method of supporting a hydrogen separation membrane system comprising selecting a hydrogen separation membrane system comprising one or more catalyst outer layers deposited on a hydrogen transport membrane layer and sealing the hydrogen separation membrane system to a porous support.

Software OT&E Guidelines. Volume 1. Software Test Manager’s Handbook

DTIC Science & Technology

1981-02-01

on reverse side If neceeary and identify by block number) The Software OT&E Guidelines is a set of handbooks prepared by the Computer / Support Systems...is one of a set of handbooks prepared by the Computer /Support Systems Division of the Test and Evaluation Directorate, Air Force Test and Evaluation...15 E. Software Maintainability .. .. ........ ... 16 F. Standard Questionnaires. .. .. ....... .... 16 1. Operator- Computer Interface Evaluation

Biodynamic Assessment of the THOR-K Manikin

DTIC Science & Technology

2013-09-01

finite element model, and for optimization of occupant seating systems and restraint system design for the MPCV and USAF aircraft ejection seats and...had the same rigid backrest, a rigid seat pan, a rigid footrest and leg support panel, but also provided side supports that restrict the motion of the... Ejection Seat (Technical Report AFRL-HE-WP-SR-2000-0002). Wright-Patterson AFB OH: Human Effectiveness Directorate, Air Force Research Laboratory

Effect of the spray application technique on the deposition of entomopathogenic nematodes in vegetables.

PubMed

Brusselman, Eva; Beck, Bert; Pollet, Sabien; Temmerman, Femke; Spanoghe, Pieter; Moens, Maurice; Nuyttens, David

2012-03-01

The present study compared entomopathogenic nematode delivery at the base of savoy cabbage and cauliflower, at the lower side of savoy cabbage and cauliflower leaves and in leek stems and the ground deposition using a five-nozzle spray boom equipped with an ISO 08 flat fan, an air induction flat fan and Twinjet spray nozzles. Additionally, an air support system and a row application system were evaluated. Approximately 40% of the applied nematodes did not reach the foot of the cabbage plants. The use of an air support system or a row application system improved nematode deposition at the savoy cabbage base. Relative nematode deposition on the lower side of savoy cabbage leaves was 27.20%, while only 2.64% of the applied nematodes reached the lower side of cauliflower leaves. After spraying leek with a standard boom, a low relative nematode deposition (26.64%) was measured in the leek stem. Nozzle type affected the distribution of nematodes in droplet spots. Nozzle type has a minor effect on the number of entomopathogenic nematodes delivered on difficult-to-reach targets. The use of modified spray application techniques directing the spray to the target site are necessary to increase the chances of contact of entomopathogenic nematodes with their target. Copyright © 2011 Society of Chemical Industry.

Data near processing support for climate data analysis

NASA Astrophysics Data System (ADS)

Kindermann, Stephan; Ehbrecht, Carsten; Hempelmann, Nils

2016-04-01

Climate data repositories grow in size exponentially. Scalable data near processing capabilities are required to meet future data analysis requirements and to replace current "data download and process at home" workflows and approaches. On one hand side, these processing capabilities should be accessible via standardized interfaces (e.g. OGC WPS), on the other side a large variety of processing tools, toolboxes and deployment alternatives have to be supported and maintained at the data/processing center. We present a community approach of a modular and flexible system supporting the development, deployment and maintenace of OGC-WPS based web processing services. This approach is organized in an open source github project (called "bird-house") supporting individual processing services ("birds", e.g. climate index calculations, model data ensemble calculations), which rely on basic common infrastructural components (e.g. installation and deployment recipes, analysis code dependencies management). To support easy deployment at data centers as well as home institutes (e.g. for testing and development) the system supports the management of the often very complex package dependency chain of climate data analysis packages as well as docker based packaging and installation. We present a concrete deployment scenario at the German Climate Computing Center (DKRZ). The DKRZ one hand side hosts a multi-petabyte climate archive which is integrated e.g. into the european ENES and worldwide ESGF data infrastructure, and on the other hand hosts an HPC center supporting (model) data production and data analysis. The deployment scenario also includes openstack based data cloud services to support data import and data distribution for bird-house based WPS web processing services. Current challenges for inter-institutionnal deployments of web processing services supporting the european and international climate modeling community as well as the climate impact community are highlighted. Also aspects supporting future WPS based cross community usage scenarios supporting data reuse and data provenance aspects are reflected.

Design and Construction of a Dual Anti-Helmholtz Magnet System for a Side-by-Side MOT

NASA Astrophysics Data System (ADS)

Narducci, Frank; Prasher, Rebecca; Adler, Charles

2012-06-01

The design of a cold-atom interferometric gradient magnetometer [1] requires two side-by-side identical atom clouds separated by approximately 1 cm for noise reduction purposes. The first step in building this system is a side-by-side MOT to capture the atoms; however, the design of a coil system to provide two zero field crossings with high field gradients separated by a small distance with low power consumption can be challenging. These three requirements are not easy to satisfy simultaneously, but there is a large ``state space'' in which we can evolve different designs. In this poster we analyze the requirements for such a system and discuss our design consisting of coils with wires wrapped on a truncated cone; this type of design has been made possible by recent advances in 3D printers, and we will go over the issues involved in printing the coil supports, building the coils and comparison of our measurements of the magnetic field to theory. We also discuss the possibility of optimizing coil design using state space searches like the Metropolis algorithm, and how these designs can be realized using 3D printing technology. [4pt] [1] Davis, J. P. and Narducci, F. A.(2008) ``A proposal for a gradient magnetometer atom interferometer,'' Journal of Modern Optics,55:19,3173 --- 3185

High-Assurance System Support through 3-D Integration

DTIC Science & Technology

2007-11-09

algorithms ), tagging, and in selected systems, offensive mecha- nisms. For example, we can exploit the control plane to tag all traffic traveling...October 2005. [35] D. Page. Theoretical use of cache memory as a cryptanalytic side-channel. Technical Report CSTR - 02-003, Department of Computer

An Analysis of the Organizational Structures Supporting PPBE within the Military Departments

DTIC Science & Technology

2008-06-01

correlation between the offices on the military side and offices on the civilian side. The top portion of the figure, the green part, is the...Management) (DASA( FIM )); Chief, Congressional Budget Liaison; Chief, Comptroller Proponency. The Military Deputy for Budget, although not directly...fall under the cognizance of the Military Deputy for Budget. The DASA( FIM ) oversees the financial management systems and processes within the Army to

Effect of Booster Seat Design on Children’s Choice of Seating Positions During Naturalistic Riding

PubMed Central

Andersson, Marianne; Bohman, Katarina; Osvalder, Anna-Lisa

2010-01-01

The purpose of this naturalistic study was to investigate the effect of booster seat design on the choice of children’s seating positions during naturalistic riding. Data was collected through observations of children during in-vehicle riding by means of a film camera. The children were positioned in high back boosters in the rear seat while a parent drove the car. The study included two different booster designs: one with large head and torso side supports, and one with small head side supports and no torso side supports. Six children between three and six years of age participated in the study. Each child was observed in both boosters. The duration of the seating positions that each child assumed was quantified. The design with large side head supports resulted more often in seating positions without head and shoulder contact with the booster’s back. There was shoulder-to-booster back contact during an average of 45% of riding time in the seat with the large head side supports compared to 75% in the seat with the small head supports. The children in the study were seated with the head in front of the front edge of the head side supports more than half the time, in both boosters. Laterally, the children were almost constantly positioned between the side supports of the booster in both seats. The observed seating positions probably reduce the desired protective effect by the side supports in side impact, and may increase the probability of head impact with the vehicle interior in frontal impact. PMID:21050601

Closeup view of the payload bay side of the aft ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Close-up view of the payload bay side of the aft crew compartment bulkhead of the Orbiter Discovery. Showing the airlock, the beam-truss attach structure supporting it and its attach points to the payload bay sill longerons. This photograph was taken in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Delay effects in the human sensory system during balancing.

PubMed

Stepan, Gabor

2009-03-28

Mechanical models of human self-balancing often use the Newtonian equations of inverted pendula. While these mathematical models are precise enough on the mechanical side, the ways humans balance themselves are still quite unexplored on the control side. Time delays in the sensory and motoric neural pathways give essential limitations to the stabilization of the human body as a multiple inverted pendulum. The sensory systems supporting each other provide the necessary signals for these control tasks; but the more complicated the system is, the larger delay is introduced. Human ageing as well as our actual physical and mental state affects the time delays in the neural system, and the mechanical structure of the human body also changes in a large range during our lives. The human balancing organ, the labyrinth, and the vision system essentially adapted to these relatively large time delays and parameter regions occurring during balancing. The analytical study of the simplified large-scale time-delayed models of balancing provides a Newtonian insight into the functioning of these organs that may also serve as a basis to support theories and hypotheses on balancing and vision.

Low energy sign illumination system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Minogue, R.W.

A low energy sign contruction is illustrated for illumination of signs of the type having translucent illuminated faces. An opaque sign border is bridged by a reflector extending generally parallel to the illuminated face and having a truncated sawtooth profile. For single sided signs, one set of sawtooth points is truncated; for dual sided signs, both set of sawtooth points are truncated. Bayonet mounted lighting sockets are mounted at apertures in the respective truncations and utilize the metallic reflective surface as one side of a low voltage (10.5-volt) ac circuit. The reflector forms a cooled heat sink mounting the bulbsmore » as well as a supporting matrix. The lamps, as mounted to this supporting matrix, are typically spaced at distances which do not exceed twice the distance of the lamp filament to the translucent face. By the expedient of using 14-V lamps, prolonged lamp life with low energy illumination results.« less

Fuel nozzle tube retention

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cihlar, David William; Melton, Patrick Benedict

A system for retaining a fuel nozzle premix tube includes a retention plate and a premix tube which extends downstream from an outlet of a premix passage defined along an aft side of a fuel plenum body. The premix tube includes an inlet end and a spring support feature which is disposed proximate to the inlet end. The premix tube extends through the retention plate. The spring retention feature is disposed between an aft side of the fuel plenum and the retention plate. The system further includes a spring which extends between the spring retention feature and the retention plate.

Flapping propulsion with side-by-side pitching foils

NASA Astrophysics Data System (ADS)

Huera-Huarte, Francisco

2016-11-01

Fish schools are one of the most common types of collective behaviour observed in nature. One of the reasons why fish swim in groups, is to reduce the cost of transport of the school. In this work we explore the propulsive performance of two foils flapping in a symmetric configuration, i.e. with an out-of-phase flapping motion. Direct thrust measurements and Particle Image Velocimetry (PIV) allowed a detailed examination of the forces and the wake generated by the system, for different kinematics (swept angles and frequencies) and shaft separations. For certain specific cases, volumetric PIV shows major differences on how the different structures in the wake of the system evolve, depending on the imposed kinematics and the side-by-side separation between the foils. Results obtained will be compared against data produced with isolated flapping foils with similar imposed kinematics, with the aim to better understand the interactions between both and the performance of the system as a whole. The author would like to acknowledge the financial support provided by the Spanish Ministerio de Economia y competitividad (MINECO) through Grant DPI2015-71645-P.

Empirically Supported Use of Psychiatric Medications in Adolescents and Adults with IBD.

PubMed

Thorkelson, Gregory; Bielefeldt, Klaus; Szigethy, Eva

2016-06-01

The use of psychotropic medications, particularly antidepressants, is common in patients with inflammatory bowel disease (IBD) in spite of a lack of their robust efficacy in this population. This review provides an overview of the use trends of different classes of antidepressant and anti-anxiety medication and their effects on mood, nervous system function, gastrointestinal physiology and immunity drawing from the literature available in the general population, other medical conditions, and when available, patients with IBD. It also covers the evidence base for the actions, efficacy, and potential complications of antidepressants organized by different classes. We conducted a PubMed search of articles relating the different drug classes probed to the terms above in different populations of interest. All types of articles were accepted including case reports and series, open and randomized trials, reviews, and expert opinion. We also examined the reference lists of the publications found. Selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs) are the most commonly prescribed agents for anxiety and depression in patients with IBD, though their efficacy for these conditions in the general population are mild to moderate at best. SSRIs are generally well tolerated, though at higher doses, they, like most antidepressant classes, can be associated with activation, serotonergic syndrome, and increased suicidal ideation. TCAs have many more serious side effects but have some shown efficacy for functional GI symptoms. A newer class, the serotonin noradrenergic reuptake inhibitors (SNRIs), can be effective for refractory depression, anxiety and chronic pain syndromes with a side effect profile similar to both SSRIs and more mild manifestations of TCAs. Mirtazapine has moderate efficacy for depression if sedation and weight gain side effects are tolerated and some small support for use in nausea and vomiting. Bupropion targets dopamine and noradrenaline reuptake and has moderate efficacy for depression, and some small support for use in fatigue and smoking cessation. Buspirone has an indication for generalized anxiety disorder though studies show only a minimal benefit. It has some growing evidence for use in functional dyspepsia. Most of these agents have physiological effects on the brain, immune system, and gastrointestinal tract (with the exception of bupropion) hence their therapeutic and side effects manifested in these systems. Antidepressant medications are frequently prescribed for depression, anxiety disorders, and chronic pain syndromes, but overall support for their efficacy is modest at best. Psychological interventions have growing support for having much more robust effects without the side effects of antidepressants and should be considered first-line treatment or at least an adjunct to psychotropic medications for these conditions.

Enhancing Health-Care Services with Mixed Reality Systems

NASA Astrophysics Data System (ADS)

Stantchev, Vladimir

This work presents a development approach for mixed reality systems in health care. Although health-care service costs account for 5-15% of GDP in developed countries the sector has been remarkably resistant to the introduction of technology-supported optimizations. Digitalization of data storing and processing in the form of electronic patient records (EPR) and hospital information systems (HIS) is a first necessary step. Contrary to typical business functions (e.g., accounting or CRM) a health-care service is characterized by a knowledge intensive decision process and usage of specialized devices ranging from stethoscopes to complex surgical systems. Mixed reality systems can help fill the gap between highly patient-specific health-care services that need a variety of technical resources on the one side and the streamlined process flow that typical process supporting information systems expect on the other side. To achieve this task, we present a development approach that includes an evaluation of existing tasks and processes within the health-care service and the information systems that currently support the service, as well as identification of decision paths and actions that can benefit from mixed reality systems. The result is a mixed reality system that allows a clinician to monitor the elements of the physical world and to blend them with virtual information provided by the systems. He or she can also plan and schedule treatments and operations in the digital world depending on status information from this mixed reality.

White-Light Whispering Gallery Mode Optical Resonator System and Method

NASA Technical Reports Server (NTRS)

Matsko, Andrey B. (Inventor); Savchenkov, Anatoliy A. (Inventor); Maleki, Lute (Inventor)

2009-01-01

An optical resonator system and method that includes a whispering-gallery mode (WGM) optical resonator that is capable of resonating across a broad, continuous swath of frequencies is provided. The optical resonator of the system is shaped to support at least one whispering gallery mode and includes a top surface, a bottom surface, a side wall, and a first curved transition region extending between the side wall and the top surface. The system further includes a coupler having a coupling surface which is arranged to face the transition region of the optical resonator and in the vicinity thereof such that an evanescent field emitted from the coupler is capable of being coupled into the optical resonator through the first curved transition region

Data-driven decision support for radiologists: re-using the National Lung Screening Trial dataset for pulmonary nodule management.

PubMed

Morrison, James J; Hostetter, Jason; Wang, Kenneth; Siegel, Eliot L

2015-02-01

Real-time mining of large research trial datasets enables development of case-based clinical decision support tools. Several applicable research datasets exist including the National Lung Screening Trial (NLST), a dataset unparalleled in size and scope for studying population-based lung cancer screening. Using these data, a clinical decision support tool was developed which matches patient demographics and lung nodule characteristics to a cohort of similar patients. The NLST dataset was converted into Structured Query Language (SQL) tables hosted on a web server, and a web-based JavaScript application was developed which performs real-time queries. JavaScript is used for both the server-side and client-side language, allowing for rapid development of a robust client interface and server-side data layer. Real-time data mining of user-specified patient cohorts achieved a rapid return of cohort cancer statistics and lung nodule distribution information. This system demonstrates the potential of individualized real-time data mining using large high-quality clinical trial datasets to drive evidence-based clinical decision-making.

Physical, social, and psychological consequences of treatment for hepatitis C : a community-based evaluation of patient-reported outcomes.

PubMed

Manos, M Michele; Ho, Chanda K; Murphy, Rosemary C; Shvachko, Valentina A

2013-01-01

Hepatitis C virus (HCV) antiviral therapy entails a long treatment course, as well as significant side effects that can lead to medication non-adherence and premature termination of treatment. Few large studies have comprehensively examined patient perspectives on the treatment experience, particularly the social and personal effects. We sought to understand how a diverse group of patients' lives were affected during HCV treatment, and to obtain suggestions about how to better support patients during treatment. On average, 13 months after therapy we interviewed by telephone a consecutive sample of 200 patients treated for hepatitis C with ribavirin and pegylated interferon in a comprehensive, integrated health plan in the years 2008-2010. Mixed (quantitative and qualitative) survey methods were used. The response rate was 68.9 %. Mean age at treatment was 51 years; 63.0 % were men; and Black, Hispanic, Asian, and White non-Hispanic racial/ethnic groups were similarly represented. Patients whose treatment was managed by nurses or clinical pharmacists (vs. physicians) were more likely to report their providers as being part of their support system (83.5 % vs. 58.9 %; p < 0.001). Most patients reported flu-like symptoms (93.5 %) and psychiatric problems (84.5 %), and 42.5 % reported side effects lasted up to 6 months after treatment. Black patients reported discontinuing treatment prematurely due to side effects more often than non-Blacks (29.4 % vs. 12.1 %; p < 0.001). Physical side effects (69.5 % of patients), psychiatric issues (43.5 %), and employment (27.4 %) were ranked among the three most difficult challenges. Patients desired help in anticipating and arranging work modifications during treatment. Most patients rated peer support, nutritional guidance, and weekly provider contact by telephone as potentially helpful resources for future patients undergoing HCV treatment. Patient perspectives can help formulate and refine HCV treatment support programs. Effective support programs for diverse populations are crucial as the complexities and costs of HCV treatment increase. The call for greater support from peers, providers, and employers demands new systems such as patient-centered care teams.

Research on ARM Numerical Control System

NASA Astrophysics Data System (ADS)

Wei, Xu; JiHong, Chen

Computerized Numerical Control (CNC) machine tools is the foundation of modern manufacturing systems, whose advanced digital technology is the key to solve the problem of sustainable development of machine tool manufacturing industry. The paper is to design CNC system embedded on ARM and indicates the hardware design and the software systems supported. On the hardware side: the driving chip of the motor control unit, as the core of components, is MCX314AL of DSP motion control which is developed by NOVA Electronics Co., Ltd. of Japan. It make convenient to control machine because of its excellent performance, simple interface, easy programming. On the Software side, the uC/OS-2 is selected as the embedded operating system of the open source, which makes a detailed breakdown of the modules of the CNC system. Those priorities are designed according to their actual requirements. The ways of communication between the module and the interrupt response are so different that it guarantees real-time property and reliability of the numerical control system. Therefore, it not only meets the requirements of the current social precision machining, but has good man-machine interface and network support to facilitate a variety of craftsmen use.

CEV Seat Attenuation System System Design Tasks

NASA Technical Reports Server (NTRS)

Goodman, Jerry R.; McMichael, James H.

2007-01-01

The Apollo crew / couch restraint system was designed to support and restrain three crew members during all phases of the mission from launch to landing. The crew couch used supported the crew for launch, landing and in-flight operations, and was foldable and removable for EVA ingress/egress through side hatch access and for in-flight access under the seat and in other areas of the crew compartment. The couch and the seat attenuation system was designed to control the impact loads imposed on the crew during landing and to remain non-functional during all other flight phases.

Effects of Progressive Body Weight Support Treadmill Forward and Backward Walking Training on Stroke Patients' Affected Side Lower Extremity's Walking Ability.

PubMed

Kim, Kyunghoon; Lee, Sukmin; Lee, Kyoungbo

2014-12-01

[Purpose] The purpose of the present study was to examine the effects of progressive body weight supported treadmill forward and backward walking training (PBWSTFBWT), progressive body weight supported treadmill forward walking training (PBWSTFWT), progressive body weight supported treadmill backward walking training (PBWSTBWT), on stroke patients' affected side lower extremity's walking ability. [Subjects and Methods] A total of 36 chronic stroke patients were divided into three groups with 12 subjects in each group. Each of the groups performed one of the progressive body weight supported treadmill training methods for 30 minute, six times per week for three weeks, and then received general physical therapy without any other intervention until the follow-up tests. For the assessment of the affected side lower extremity's walking ability, step length of the affected side, stance phase of the affected side, swing phase of the affected side, single support of the affected side, and step time of the affected side were measured using optogait and the symmetry index. [Results] In the within group comparisons, all the three groups showed significant differences between before and after the intervention and in the comparison of the three groups, the PBWSTFBWT group showed more significant differences in all of the assessed items than the other two groups. [Conclusion] In the present study progressive body weight supported treadmill training was performed in an environment in which the subjects were actually walked, and PBWSTFBWT was more effective at efficiently training stroke patients' affected side lower extremity's walking ability.

Airfoil-Shaped Fluid Flow Tool for Use in Making Differential Measurements

NASA Technical Reports Server (NTRS)

England, John Dwight (Inventor); Kelley, Anthony R. (Inventor); Cronise, Raymond J. (Inventor)

2014-01-01

A fluid flow tool includes an airfoil structure and a support arm. The airfoil structure's high-pressure side and low-pressure side are positioned in a conduit by the support arm coupled to the conduit. The high-pressure and low-pressure sides substantially face opposing walls of the conduit. At least one measurement port is formed in the airfoil structure at each of its high-pressure side and low-pressure side. A first manifold, formed in the airfoil structure and in fluid communication with each measurement port so-formed at the high-pressure side, extends through the airfoil structure and support arm to terminate and be accessible at the exterior wall of the conduit. A second manifold, formed in the airfoil structure and in fluid communication with each measurement port so-formed at the low-pressure side, extends through the airfoil structure and support arm to terminate and be accessible at the exterior wall of the conduit.

Supported microporous ceramic membranes

DOEpatents

Webster, Elizabeth; Anderson, Marc

1993-01-01

A method for permformation of microporous ceramic membranes onto a porous support includes placing a colloidal suspension of metal or metal oxide particles on one side of the porous support and exposing the other side of the porous support to a drying stream of gas or a reactive gas stream so that the particles are deposited on the drying side of the support as a gel. The gel so deposited can be sintered to form a supported ceramic membrane useful for ultrafiltration, reverse osmosis, or molecular sieving having mean pore sizes less than 100 Angstroms.

Supported microporous ceramic membranes

DOEpatents

Webster, E.; Anderson, M.

1993-12-14

A method for the formation of microporous ceramic membranes onto a porous support includes placing a colloidal suspension of metal or metal oxide particles on one side of the porous support and exposing the other side of the porous support to a drying stream of gas or a reactive gas stream so that the particles are deposited on the drying side of the support as a gel. The gel so deposited can be sintered to form a supported ceramic membrane useful for ultrafiltration, reverse osmosis, or molecular sieving having mean pore sizes less than 100 Angstroms. 4 figures.

Detail view of the starboard side of the aft fuselage ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view of the starboard side of the aft fuselage of the Orbiter Discovery in the Orbiter Processing Facility at Kennedy Space Center with the Orbiter Maneuvering/Reaction Control Systems Pod removed and exposing the insulating foil used to protect the orbiter structure from the heat generated by the maneuvering and reaction control engines. Also note in the view that the aft fuselage access door has bee removed and also note the ground support equipment attached to the T-0 umbilical plate in the lower left of the view. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

An Introduction to MAMA (Meta-Analysis of MicroArray data) System.

PubMed

Zhang, Zhe; Fenstermacher, David

2005-01-01

Analyzing microarray data across multiple experiments has been proven advantageous. To support this kind of analysis, we are developing a software system called MAMA (Meta-Analysis of MicroArray data). MAMA utilizes a client-server architecture with a relational database on the server-side for the storage of microarray datasets collected from various resources. The client-side is an application running on the end user's computer that allows the user to manipulate microarray data and analytical results locally. MAMA implementation will integrate several analytical methods, including meta-analysis within an open-source framework offering other developers the flexibility to plug in additional statistical algorithms.

Demonstration of Hybrid Multilayer Insulation for Fixed Thickness Applications

NASA Astrophysics Data System (ADS)

Johnson, W. L.; Fesmire, J. E.; Heckle, K. W.

2015-12-01

Cryogenic multilayer insulation (MLI) systems provide both conductive and radiative thermal insulation performance. The use of radiation shields with low conductivity spacers in between are required. By varying the distance and types of the spacers between the radiation shields, the relative radiation and conduction heat transfers can be manipulated. However, in most systems, there is a fixed thickness or volume allocated to the insulation. To understand how various combinations of different multilayer insulation (MLI) systems work together and to further validate thermal models of hybrid MLI systems, test data are needed. The MLI systems include combinations of Load-Bearing MLI (LB-MLI) and traditional MLI (tMLI). To further simulate the space launch vehicle case wherein both ambient pressure and vacuum environments are addressed, different cold-side thermal insulation substrates were included for select tests. The basic hybrid construction consists of some number of layers of LB-MLI on the cold side of the insulation system followed by layers of tMLI on the warm side of the system. The advantages of LB-MLI on the cold side of the insulation blanket are that its low layer density (0.5 - 0.6 layer/mm) is better suited for lower temperature applications and is a structural component to support heat interception shields that may be placed within the blanket. The advantage of tMLI systems on the warm side is that radiation is more dominant than conduction at warmer temperatures, so that a higher layer density is desired (2 - 3 layer/mm) and less effort need be put into minimizing conduction heat transfer. Liquid nitrogen boiloff test data using a cylindrical calorimeter are presented along with analysis for spacecraft tank applications.

Development of virtual reality exercise of hand motion assist robot for rehabilitation therapy by patient self-motion control.

PubMed

Ueki, Satoshi; Nishimoto, Yutaka; Abe, Motoyuki; Kawasaki, Haruhisa; Ito, Satoshi; Ishigure, Yasuhiko; Mizumoto, Jun; Ojika, Takeo

2008-01-01

This paper presents a virtual reality-enhanced hand rehabilitation support system with a symmetric master-slave motion assistant for independent rehabilitation therapies. Our aim is to provide fine motion exercise for a hand and fingers, which allows the impaired hand of a patient to be driven by his or her healthy hand on the opposite side. Since most disabilities caused by cerebral vascular accidents or bone fractures are hemiplegic, we adopted a symmetric master-slave motion assistant system in which the impaired hand is driven by the healthy hand on the opposite side. A VR environment displaying an effective exercise was created in consideration of system's characteristic. To verify the effectiveness of this system, a clinical test was executed by applying to six patients.

Potential reduction exposure products and FDA tobacco and regulation: a CNS call to action.

PubMed

Heath, Janie; Andrews, Jeannette; Balkstra, Cindy R

2004-01-01

A new generation of tobacco harm reduction products is stirring controversy and confusion among healthcare providers. These products, known as "potential reduction exposure products" (PREPs), can be described in terms of reported scientific evidence, as "the good, the bad, and the ugly." On the good side, there is sufficient scientific evidence to support the use of Commit, a new over-the-counter nicotine lozenge PREP, approved for smoking cessation. On the bad side, there is no scientific evidence to support the use of Ariva, another over-the-counter nicotine lozenge PREP, marketed as an alternative to cigarettes when smoking is restricted. On the ugly side, both of these PREPs are nicotine delivery systems with "candy-like" appearances; however, one (Commit) has the Food and Drug Administration (FDA) approval and the other (Ariva) does not. This article provides an overview of PREPs and strategies to help clinical nurse specialists (CNSs) address tobacco harm reduction issues.

Systemic bias in the medical literature on androgen deprivation therapy and its implication to clinical practice.

PubMed

Phillips, J L; Wassersug, R J; McLeod, D L

2012-12-01

LHRH agonists are used for androgen deprivation therapy (ADT) to treat prostate cancer, but have many side effects that reduce of the quality of life of prostate cancer patients and their partners. Patients are poorly informed about the side effects of these drugs and how to manage them. To test the hypothesis that there is bias in the peer-reviewed literature on ADT that correlates with an association between authors and the luteinising hormone-releasing hormone (LHRH) agonists pharmaceutical industry. We assessed 155 articles on ADT published in English-language peer-reviewed journals in terms of how comprehensive they were in acknowledging LHRH agonists' side effects. Although the literature regarding ADT is substantial, the vast majority of articles failed to acknowledge many of the more stressful side effects of ADT for patients and their partners. Articles most likely to acknowledge the psychosocial impact of ADT were significantly less likely to have had industrial support than those articles that did not mention those side effects. Alternative treatments to the LHRH agonists were rarely mentioned. Authors who indicated some association with a pharmaceutical company tended to minimise the side effects of LHRH agonists and not acknowledge alternatives to the LHRH agonists for ADT. Industrial support is associated with a proliferation of articles published in the peer-reviewed literature directed at practising physicians. Such flooding of the literature may, in part, limit physicians' knowledge of the side effects of these drugs and, in turn, account for the poor knowledge that patients on LHRH agonists have about the drugs they are taking and ways to manage their side effects. © 2012 Blackwell Publishing Ltd.

Metal oxide membranes for gas separation

DOEpatents

Anderson, Marc A.; Webster, Elizabeth T.; Xu, Qunyin

1994-01-01

A method for permformation of a microporous ceramic membrane onto a porous support includes placing a colloidal suspension of metal oxide particles on one side of the porous support and exposing the other side of the porous support to a drying stream of gas or a reactive gas stream so that the particles are deposited on the drying side of the support as a gel. The gel so deposited can be sintered to form a supported ceramic membrane having mean pore sizes less than 30 Angstroms and useful for ultrafiltration, reverse osmosis, or gas separation.

Metal oxide membranes for gas separation

DOEpatents

Anderson, M.A.; Webster, E.T.; Xu, Q.

1994-08-30

A method for formation of a microporous ceramic membrane onto a porous support includes placing a colloidal suspension of metal oxide particles on one side of the porous support and exposing the other side of the porous support to a drying stream of gas or a reactive gas stream so that the particles are deposited on the drying side of the support as a gel. The gel so deposited can be sintered to form a supported ceramic membrane having mean pore sizes less than 30 Angstroms and useful for ultrafiltration, reverse osmosis, or gas separation. 4 figs.

Stabilized PV system

DOEpatents

Dinwoodie, Thomas L.

2002-12-17

A stabilized PV system comprises an array of photovoltaic (PV) assemblies mounted to a support surface. Each PV assembly comprises a PV module and a support assembly securing the PV module to a position overlying the support surface. The array of modules is circumscribed by a continuous, belt-like perimeter assembly. Cross strapping, extending above, below or through the array, or some combination of above, below and through the array, secures a first position along the perimeter assembly to at least a second position along the perimeter assembly thereby stabilizing the array against wind uplift forces. The first and second positions may be on opposite sides on the array.

Design of a Clinical Information Management System to Support DNA Analysis Laboratory Operation

PubMed Central

Dubay, Christopher J.; Zimmerman, David; Popovich, Bradley

1995-01-01

The LabDirector system has been developed at the Oregon Health Sciences University to support the operation of our clinical DNA analysis laboratory. Through an iterative design process which has spanned two years, we have produced a system that is both highly tailored to a clinical genetics production laboratory and flexible in its implementation, to support the rapid growth and change of protocols and methodologies in use in the field. The administrative aspects of the system are integrated with an enterprise schedule management system. The laboratory side of the system is driven by a protocol modeling and execution system. The close integration between these two aspects of the clinical laboratory facilitates smooth operations, and allows management to accurately measure costs and performance. The entire application has been designed and documented to provide utility to a wide range of clinical laboratory environments.

Data acquisition system for operational earth observation missions

NASA Technical Reports Server (NTRS)

Deerwester, J. M.; Alexander, D.; Arno, R. D.; Edsinger, L. E.; Norman, S. M.; Sinclair, K. F.; Tindle, E. L.; Wood, R. D.

1972-01-01

The data acquisition system capabilities expected to be available in the 1980 time period as part of operational Earth observation missions are identified. By data acquisition system is meant the sensor platform (spacecraft or aircraft), the sensors themselves and the communication system. Future capabilities and support requirements are projected for the following sensors: film camera, return beam vidicon, multispectral scanner, infrared scanner, infrared radiometer, microwave scanner, microwave radiometer, coherent side-looking radar, and scatterometer.

An IT Architecture for Systems Medicine.

PubMed

Ganzinger, Matthias; Gietzelt, Matthias; Karmen, Christian; Firnkorn, Daniel; Knaup, Petra

2015-01-01

Systems medicine aims to support treatment of complex diseases like cancer by integrating all available data for the disease. To provide such a decision support in clinical practice, a suitable IT architecture is necessary. We suggest a generic architecture comprised of the following three layers: data representation, decision support, and user interface. For the systems medicine research project "Clinically-applicable, omics-based assessment of survival, side effects, and targets in multiple myeloma" (CLIOMMICS) we developed a concrete instance of the generic architecture. We use i2b2 for representing the harmonized data. Since no deterministic model exists for multiple myeloma we use case-based reasoning for decision support. For clinical practice, visualizations of the results must be intuitive and clear. At the same time, they must communicate the uncertainty immanent in stochastic processes. Thus, we develop a specific user interface for systems medicine based on the web portal software Liferay.

Asynchronous data change notification between database server and accelerator controls system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fu, W.; Morris, J.; Nemesure, S.

2011-10-10

Database data change notification (DCN) is a commonly used feature. Not all database management systems (DBMS) provide an explicit DCN mechanism. Even for those DBMS's which support DCN (such as Oracle and MS SQL server), some server side and/or client side programming may be required to make the DCN system work. This makes the setup of DCN between database server and interested clients tedious and time consuming. In accelerator control systems, there are many well established software client/server architectures (such as CDEV, EPICS, and ADO) that can be used to implement data reflection servers that transfer data asynchronously to anymore » client using the standard SET/GET API. This paper describes a method for using such a data reflection server to set up asynchronous DCN (ADCN) between a DBMS and clients. This method works well for all DBMS systems which provide database trigger functionality. Asynchronous data change notification (ADCN) between database server and clients can be realized by combining the use of a database trigger mechanism, which is supported by major DBMS systems, with server processes that use client/server software architectures that are familiar in the accelerator controls community (such as EPICS, CDEV or ADO). This approach makes the ADCN system easy to set up and integrate into an accelerator controls system. Several ADCN systems have been set up and used in the RHIC-AGS controls system.« less

A review method for UML requirements analysis model employing system-side prototyping.

PubMed

Ogata, Shinpei; Matsuura, Saeko

2013-12-01

User interface prototyping is an effective method for users to validate the requirements defined by analysts at an early stage of a software development. However, a user interface prototype system offers weak support for the analysts to verify the consistency of the specifications about internal aspects of a system such as business logic. As the result, the inconsistency causes a lot of rework costs because the inconsistency often makes the developers impossible to actualize the system based on the specifications. For verifying such consistency, functional prototyping is an effective method for the analysts, but it needs a lot of costs and more detailed specifications. In this paper, we propose a review method so that analysts can verify the consistency among several different kinds of diagrams in UML efficiently by employing system-side prototyping without the detailed model. The system-side prototype system does not have any functions to achieve business logic, but visualizes the results of the integration among the diagrams in UML as Web pages. The usefulness of our proposal was evaluated by applying our proposal into a development of Library Management System (LMS) for a laboratory. This development was conducted by a group. As the result, our proposal was useful for discovering the serious inconsistency caused by the misunderstanding among the members of the group.

Suppression of Rn-daughters in the DarkSide Dark Matter Search

NASA Astrophysics Data System (ADS)

Cao, Huajie; Borexino; DarkSide Collaboration

2011-04-01

Alpha-emitting activity from radon daughters will be an important source of background for the next generation of direct dark matter searches. A vacuum swing adsorption (VSA) system with a radon suppression factor better than 100 was constructed and operated to purify the make-up air to the clean room that was used for the construction of the Borexino nylon vessels. The system was recently refurbished and upgraded for use in the construction and assembly of the DarkSide-50 dark matter detector. The VSA system consists of two charcoal-filled tanks cycled between atmospheric pressure and 10 mbar. I will discuss the design and operation of the system and detail its performance. Results from this test may inform the development of radon filters dedicated to support the next generation of dark matter and double beta decay detectors.

Muscle Coactivation during Stability Exercises in Rhythmic Gymnastics: A Two-Case Study.

PubMed

Rutkowska-Kucharska, Alicja; Szpala, Agnieszka; Jaroszczuk, Sebastian; Sobera, Małgorzata

2018-01-01

Balance exercises in rhythmic gymnastics are performed on tiptoes, which causes overload of foot joints. This study aimed to evaluate the engagement of muscles stabilizing ankle and knee joints in balance exercises and determine exercises which may lead to ankle and knee joint injuries. It was hypothesized that long-term training has an influence on balance control and efficient use of muscles in their stabilizing function. Two rhythmic gymnasts (8 and 21 years old) performed balances on tiptoes (side split with hand support, ring with hand support) and on a flat foot (back split without hand support exercise). Surface electromyography, ground reaction forces, and kinematic parameters of movement were measured. The measuring systems applied were synchronized with the BTS SMART system. The results show the necessity to limit balance exercises on tiptoes in children because gastrocnemius medialis (GM) and gastrocnemius lateralis (GL) activity significantly exceeds their activity. Ankle joint stabilizing activity of GM and GL muscles in the younger gymnast was more important than in the older one. Performing this exercise, the younger gymnast distributed load on the anterior side of the foot while the older one did so on its posterior. Gymnastics coaches should be advised to exclude ring with hand support exercise from the training of young gymnasts.

Muscle Coactivation during Stability Exercises in Rhythmic Gymnastics: A Two-Case Study

PubMed Central

Jaroszczuk, Sebastian

2018-01-01

Balance exercises in rhythmic gymnastics are performed on tiptoes, which causes overload of foot joints. This study aimed to evaluate the engagement of muscles stabilizing ankle and knee joints in balance exercises and determine exercises which may lead to ankle and knee joint injuries. It was hypothesized that long-term training has an influence on balance control and efficient use of muscles in their stabilizing function. Two rhythmic gymnasts (8 and 21 years old) performed balances on tiptoes (side split with hand support, ring with hand support) and on a flat foot (back split without hand support exercise). Surface electromyography, ground reaction forces, and kinematic parameters of movement were measured. The measuring systems applied were synchronized with the BTS SMART system. The results show the necessity to limit balance exercises on tiptoes in children because gastrocnemius medialis (GM) and gastrocnemius lateralis (GL) activity significantly exceeds their activity. Ankle joint stabilizing activity of GM and GL muscles in the younger gymnast was more important than in the older one. Performing this exercise, the younger gymnast distributed load on the anterior side of the foot while the older one did so on its posterior. Gymnastics coaches should be advised to exclude ring with hand support exercise from the training of young gymnasts. PMID:29808099

What to Expect During a Mastectomy Surgery

MedlinePlus

... Managing Side Effects and Supportive Care Managing Pain Quality of Life Survival and Risk of Recurrence Breast Cancer Recurrence ... Pain Managing Side Effects and Supportive Care Support Quality of Life Survivorship Topics Survivorship Topics Medical Care After Treatment ...

NREL and Hawaiian Electric Navigate Uncharted Waters of Energy

Science.gov Websites

potential grid impact of adding customer-side storage to rooftop solar systems-a scenario that could soon Systems Integration Facility's (ESIF's) power hardware-in-the-loop capability. NREL's ESIF was one of the justify activation of a specific grid support function called "volt-var control" for all new

Structural heat pipe. [for spacecraft wall thermal insulation system

NASA Technical Reports Server (NTRS)

Ollendorf, S. (Inventor)

1974-01-01

A combined structural reinforcing element and heat transfer member is disclosed for placement between a structural wall and an outer insulation blanket. The element comprises a heat pipe, one side of which supports the outer insulation blanket, the opposite side of which is connected to the structural wall. Heat penetrating through the outer insulation blanket directly reaches the heat pipe and is drawn off, thereby reducing thermal gradients in the structural wall. The element, due to its attachment to the structural wall, further functions as a reinforcing member.

Detail view looking aft along the starboard side of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view looking aft along the starboard side of the Orbiter Discovery where the forward section meets the mid-fuselage. Note the head of the jack stand and its mechanism to connect to the one of the forward hoist attach points of the orbiter. Also note the support structure of the service platforms. This view was taken from the service platform in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Putting Theory Into Practice: A Case Study of Diabetes-Related Behavioral Change Interventions on Chicago's South Side

PubMed Central

Peek, Monica E.; Ferguson, Molly J.; Roberson, Tonya P.; Chin, Marshall H.

2014-01-01

Diabetes self-management is central to diabetes care overall, and much of self-management entails individual behavior change, particularly around dietary patterns and physical activity. Yet individual-level behavior change remains a challenge for many persons with diabetes, particularly for racial/ethnic minorities who disproportionately face barriers to diabetes-related behavioral changes. Through the South Side Diabetes Project, officially known as “Improving Diabetes Care and Outcomes on the South Side of Chicago,” our team sought to improve health outcomes and reduce disparities among residents in the largely working-class African American communities that comprise Chicago's South Side. In this article, we describe several aspects of the South Side Diabetes Project that are directly linked to patient behavioral change, and discuss the theoretical frameworks we used to design and implement our programs. We also briefly discuss more downstream program elements (e.g., health systems change) that provide additional support for patient-level behavioral change. PMID:25359248

Putting theory into practice: a case study of diabetes-related behavioral change interventions on Chicago's South Side.

PubMed

Peek, Monica E; Ferguson, Molly J; Roberson, Tonya P; Chin, Marshall H

2014-11-01

Diabetes self-management is central to diabetes care overall, and much of self-management entails individual behavior change, particularly around dietary patterns and physical activity. Yet individual-level behavior change remains a challenge for many persons with diabetes, particularly for racial/ethnic minorities who disproportionately face barriers to diabetes-related behavioral changes. Through the South Side Diabetes Project, officially known as "Improving Diabetes Care and Outcomes on the South Side of Chicago," our team sought to improve health outcomes and reduce disparities among residents in the largely working-class African American communities that comprise Chicago's South Side. In this article, we describe several aspects of the South Side Diabetes Project that are directly linked to patient behavioral change, and discuss the theoretical frameworks we used to design and implement our programs. We also briefly discuss more downstream program elements (e.g., health systems change) that provide additional support for patient-level behavioral change. © 2014 Society for Public Health Education.

TeleProbe: design and development of an efficient system for telepathology

NASA Astrophysics Data System (ADS)

Ahmed, Wamiq M.; Robinson, J. Paul; Ghafoor, Arif

2005-10-01

This paper describes an internet-based system for telepathology. This system provides support for multiple users and exploits the opportunities for optimization that arise in multi-user environment. Techniques for increasing system responsiveness by improving resource utilization and lowering network traffic are explored. Some of the proposed optimizations include an auto-focus module, client and server side caching, and request reordering. These systems can be an economic solution not only for remote pathology consultation but also for pathology and biology education.

A collaborative framework for contributing DICOM RT PHI (Protected Health Information) to augment data mining in clinical decision support

NASA Astrophysics Data System (ADS)

Deshpande, Ruchi; Thuptimdang, Wanwara; DeMarco, John; Liu, Brent J.

2014-03-01

We have built a decision support system that provides recommendations for customizing radiation therapy treatment plans, based on patient models generated from a database of retrospective planning data. This database consists of relevant metadata and information derived from the following DICOM objects - CT images, RT Structure Set, RT Dose and RT Plan. The usefulness and accuracy of such patient models partly depends on the sample size of the learning data set. Our current goal is to increase this sample size by expanding our decision support system into a collaborative framework to include contributions from multiple collaborators. Potential collaborators are often reluctant to upload even anonymized patient files to repositories outside their local organizational network in order to avoid any conflicts with HIPAA Privacy and Security Rules. We have circumvented this problem by developing a tool that can parse DICOM files on the client's side and extract de-identified numeric and text data from DICOM RT headers for uploading to a centralized system. As a result, the DICOM files containing PHI remain local to the client side. This is a novel workflow that results in adding only relevant yet valuable data from DICOM files to the centralized decision support knowledge base in such a way that the DICOM files never leave the contributor's local workstation in a cloud-based environment. Such a workflow serves to encourage clinicians to contribute data for research endeavors by ensuring protection of electronic patient data.

Data archiving and serving system implementation in CLEP's GRAS Core System

NASA Astrophysics Data System (ADS)

Zuo, Wei; Zeng, Xingguo; Zhang, Zhoubin; Geng, Liang; Li, Chunlai

2017-04-01

The Ground Research & Applications System(GRAS) is one of the five systems of China's Lunar Exploration Project(CLEP), it is responsible for data acquisition, processing, management and application, and it is also the operation control center during satellite in-orbit and payload operation management. Chang'E-1, Chang'E-2 and Chang'E-3 have collected abundant lunar exploration data. The aim of this work is to present the implementation of data archiving and Serving in CLEP's GRAS Core System software. This first approach provides a client side API and server side software allowing the creation of a simplified version of CLEPDB data archiving software, and implements all required elements to complete data archiving flow from data acquisition until its persistent storage technology. The client side includes all necessary components that run on devices that acquire or produce data, distributing and streaming to configure remote archiving servers. The server side comprises an archiving service that stores into PDS files all received data. The archiving solution aims at storing data coming for the Data Acquisition Subsystem, the Operation Management Subsystem, the Data Preprocessing Subsystem and the Scientific Application & Research Subsystem. The serving solution aims at serving data for the various business systems, scientific researchers and public users. The data-driven and component clustering methods was adopted in this system, the former is used to solve real-time data archiving and data persistence services; the latter is used to keep the continuous supporting ability of archive and service to new data from Chang'E Mission. Meanwhile, it can save software development cost as well.

Advanced cathode materials for polymer electrolyte fuel cells based on pt/ metal oxides: from model electrodes to catalyst systems.

PubMed

Fabbri, Emiliana; Pătru, Alexandra; Rabis, Annett; Kötz, Rüdiger; Schmidt, Thomas J

2014-01-01

The development of stable catalyst systems for application at the cathode side of polymer electrolyte fuel cells (PEFCs) requires the substitution of the state-of-the-art carbon supports with materials showing high corrosion resistance in a strongly oxidizing environment. Metal oxides in their highest oxidation state can represent viable support materials for the next generation PEFC cathodes. In the present work a multilevel approach has been adopted to investigate the kinetics and the activity of Pt nanoparticles supported on SnO2-based metal oxides. Particularly, model electrodes made of SnO2 thin films supporting Pt nanoparticles, and porous catalyst systems made of Pt nanoparticles supported on Sb-doped SnO2 high surface area powders have been investigated. The present results indicate that SnO2-based supports do not modify the oxygen reduction reaction mechanism on the Pt nanoparticle surface, but rather lead to catalysts with enhanced specific activity compared to Pt/carbon systems. Different reasons for the enhancement in the specific activity are considered and discussed.

Strategies to increase demand for maternal health services in resource-limited settings: challenges to be addressed.

PubMed

Elmusharaf, Khalifa; Byrne, Elaine; O'Donovan, Diarmuid

2015-09-08

Universal health access will not be achieved unless women are cared for in their own communities and are empowered to take decisions about their own health in a supportive environment. This will only be achieved by community-based demand side interventions for maternal health access. In this review article, we highlight three common strategies to increase demand-side barriers to maternal healthcare access and identify the main challenges that still need to be addressed for these strategies to be effective. Common demand side strategies can be grouped into three categories:(i) Financial incentives/subsidies; (ii) Enhancing patient transfer, and; (iii) Community involvement. The main challenges in assessing the effectiveness or efficacy of these interventions or strategies are the lack of quality evidence on their outcome and impact and interventions not integrated into existing health or community systems. However, what is highlighted in this review and overlooked in most of the published literature on this topic is the lack of knowledge about the context in which these strategies are to be implemented. We suggest three challenges that need to be addressed to create a supportive environment in which these demand-side strategies can effectively improve access to maternal health services. These include: addressing decision-making norms, engaging in intergenerational dialogue, and designing contextually appropriate communication strategies.

Inductrack III configuration--a maglev system for high loads

DOEpatents

Post, Richard F

2015-03-24

Inductrack III configurations are suited for use in transporting heavy freight loads. Inductrack III addresses a problem associated with the cantilevered track of the Inductrack II configuration. The use of a cantilevered track could present mechanical design problems in attempting to achieve a strong enough track system such that it would be capable of supporting very heavy loads. In Inductrack III, the levitating portion of the track can be supported uniformly from below, as the levitating Halbach array used on the moving vehicle is a single-sided one, thus does not require the cantilevered track as employed in Inductrack II.

Inductrack III configuration--a maglev system for high loads

DOEpatents

Post, Richard F

2013-11-12

Inductrack III configurations are suited for use in transporting heavy freight loads. Inductrack III addresses a problem associated with the cantilevered track of the Inductrack II configuration. The use of a cantilevered track could present mechanical design problems in attempting to achieve a strong enough track system such that it would be capable of supporting very heavy loads. In Inductrack III, the levitating portion of the track can be supported uniformly from below, as the levitating Halbach array used on the moving vehicle is a single-sided one, thus does not require the cantilevered track as employed in Inductrack II.

77 FR 51720 - Airworthiness Directives; The Boeing Company Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-27

... clamps installed within the left environmental cooling systems (ECS) bay, which could allow wiring to... support clamps installed within the left ECS bay, which is a flammable leakage zone. Use of incorrect wire... bundle within the left side ECS bay, and corrective actions if necessary. Corrective actions include...

Orbital friction stir weld system

NASA Technical Reports Server (NTRS)

Ding, R. Jeffrey (Inventor); Carter, Robert W. (Inventor)

2001-01-01

This invention is an apparatus for joining the ends of two cylindrical (i.e., pipe-shaped) sections together with a friction stir weld. The apparatus holds the two cylindrical sections together and provides back-side weld support as it makes a friction stir weld around the circumference of the joined ends.

CELLAR LOOKING NORTH (REAR SIDE OF BUILDING). AT LEFT ARE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

CELLAR LOOKING NORTH (REAR SIDE OF BUILDING). AT LEFT ARE ORIGINAL BRICK ARCHES SUPPORTING BRICK PARTITIONS UPSTAIRS. AT CENTER IS BRICK PIER SUPPORTING MODERN SAFE. AT RIGHT IS BRICK PIER AND VAULT SUPPORTING ORIGINAL SAFE - Kid-Chandler House, 323 Walnut Street, Philadelphia, Philadelphia County, PA

[Machine Learning-based Prediction of Seizure-inducing Action as an Adverse Drug Effect].

PubMed

Gao, Mengxuan; Sato, Motoshige; Ikegaya, Yuji

2018-01-01

　During the preclinical research period of drug development, animal testing is widely used to help screen out a drug's dangerous side effects. However, it remains difficult to predict side effects within the central nervous system. Here, we introduce a machine learning-based in vitro system designed to detect seizure-inducing side effects before clinical trial. We recorded local field potentials from the CA1 alveus in acute mouse neocortico-hippocampal slices that were bath-perfused with each of 14 different drugs, and at 5 different concentrations of each drug. For each of these experimental conditions, we collected seizure-like neuronal activity and merged their waveforms as one graphic image, which was further converted into a feature vector using Caffe, an open framework for deep learning. In the space of the first two principal components, the support vector machine completely separated the vectors (i.e., doses of individual drugs) that induced seizure-like events, and identified diphenhydramine, enoxacin, strychnine and theophylline as "seizure-inducing" drugs, which have indeed been reported to induce seizures in clinical situations. Thus, this artificial intelligence-based classification may provide a new platform to pre-clinically detect seizure-inducing side effects of drugs.

Blind-Side, High-Temperature Fastener Lock

NASA Technical Reports Server (NTRS)

Matza, E. C.; While, D. M.

1985-01-01

Formed-in-place staple provides positive mechanical lock. Post-supported, advanced carbon/carbon standoff panels, currently under consideration as alternate thermal protection system for Shuttle orbiter, locking feature applicable to temperatures of 1,600 degrees F (870 degrees C) and higher and employable after panel installed, resulting in blind application. Blind-side locking technique employs wire staple inserted into grooves in post, formed in place by ramped portion of post grooves. This splays out wire ends that move into castellated end of grommet, mechanically locking post and grommet against relative rotation. Splayed ends provide mechanical lock to prevent wire from falling out.

The STRATEGY project: decision tools to aid sustainable restoration and long-term management of contaminated agricultural ecosystems.

PubMed

Howard, B J; Beresford, N A; Nisbet, A; Cox, G; Oughton, D H; Hunt, J; Alvarez, B; Andersson, K G; Liland, A; Voigt, G

2005-01-01

The STRATEGY project (Sustainable Restoration and Long-Term Management of Contaminated Rural, Urban and Industrial Ecosystems) aimed to provide a holistic decision framework for the selection of optimal restoration strategies for the long-term sustainable management of contaminated areas in Western Europe. A critical evaluation was carried out of countermeasures and waste disposal options, from which compendia of state-of-the-art restoration methods were compiled. A decision support system capable of optimising spatially varying restoration strategies, that considered the level of averted dose, costs (including those of waste disposal) and environmental side effects was developed. Appropriate methods of estimating indirect costs associated with side effects and of communicating with stakeholders were identified. The importance of stakeholder consultation at a local level and of ensuring that any response is site and scenario specific were emphasised. A value matrix approach was suggested as a method of addressing social and ethical issues within the decision-making process, and was designed to be compatible with both the countermeasure compendia and the decision support system. The applicability and usefulness of STRATEGY outputs for food production systems in the medium to long term is assessed.

11. INTERIOR OF ATTIC, VIEW FROM SOUTH END LOOKING AT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. INTERIOR OF ATTIC, VIEW FROM SOUTH END LOOKING AT ROOF STRUCTURE ON EAST SIDE OF BUILDING. NOTE HEAVY TIMBER TRUSS SYSTEM WITH THIN, VERTICAL METAL SUPPORTS. THESE SUPPORTS WERE PROBABLY ADDED AFTER ALTERATIONS ON THE LOWER FLOORS IN THE LATE 1930s. THE PEELING PAINT ON THE TRUSS TIMBERS AND BEADED HORIZONTAL PANELING FURTHER INDICATES THAT THIS SPACE WAS FINISHED FOR USE AS A PRODUCTION AREA. - Graniteville Mill, Marshall Street, Graniteville, Aiken County, SC

Nosiheptide Biosynthesis Featuring a Unique Indole Side Ring Formation on the Characteristic Thiopeptide Framework

PubMed Central

Yu, Yi; Duan, Lian; Zhang, Qi; Liao, Rijing; Ding, Ying; Pan, Haixue; Wendt-Pienkowski, Evelyn; Tang, Gongli; Shen, Ben; Liu, Wen

2009-01-01

Nosiheptide (NOS), belonging to the e series of thiopeptide antibiotics that exhibit potent activity against various bacterial pathogens, bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Here, cloning, sequencing and characterization of the nos gene cluster from Streptomyces actuosus ATCC 25421 as a model for this series of thiopeptides has unveiled new insights into their biosynthesis. Bioinformatics-based sequence analysis and in vivo investigation into the gene functions show that NOS biosynthesis shares a common strategy with recently characterized b or c series thiopeptides for forming the characteristic macrocyclic core, which features a ribosomally synthesized precursor peptide with conserved posttranslational modifications. However, it apparently proceeds via a different route for tailoring the thiopeptide framework, allowing the final product to exhibit the distinct structural characteristics of e series thiopeptides, such as the indole side ring system. Chemical complementation supports the notion that the S-adenosylmethionine (AdoMet)-dependent protein NosL may play a central role in converting Trp to the key 3-methylindole moiety by an unusual carbon side chain rearrangement, most likely via a radical-initiated mechanism. Characterization of the indole side ring-opened analog of NOS from the nosN mutant strain is consistent with the proposed methyltransferase activity of its encoded protein, shedding light into the timing of the individual steps for indole side ring biosynthesis. These results also suggest the feasibility of engineering novel thiopeptides for drug discovery by manipulating the NOS biosynthetic machinery. PMID:19678698

Design and implementation of a risk assessment module in a spatial decision support system

NASA Astrophysics Data System (ADS)

Zhang, Kaixi; van Westen, Cees; Bakker, Wim

2014-05-01

The spatial decision support system named 'Changes SDSS' is currently under development. The goal of this system is to analyze changing hydro-meteorological hazards and the effect of risk reduction alternatives to support decision makers in choosing the best alternatives. The risk assessment module within the system is to assess the current risk, analyze the risk after implementations of risk reduction alternatives, and analyze the risk in different future years when considering scenarios such as climate change, land use change and population growth. The objective of this work is to present the detailed design and implementation plan of the risk assessment module. The main challenges faced consist of how to shift the risk assessment from traditional desktop software to an open source web-based platform, the availability of input data and the inclusion of uncertainties in the risk analysis. The risk assessment module is developed using Ext JS library for the implementation of user interface on the client side, using Python for scripting, as well as PostGIS spatial functions for complex computations on the server side. The comprehensive consideration of the underlying uncertainties in input data can lead to a better quantification of risk assessment and a more reliable Changes SDSS, since the outputs of risk assessment module are the basis for decision making module within the system. The implementation of this module will contribute to the development of open source web-based modules for multi-hazard risk assessment in the future. This work is part of the "CHANGES SDSS" project, funded by the European Community's 7th Framework Program.

Spatial decision supporting for winter wheat irrigation and fertilizer optimizing in North China Plain

NASA Astrophysics Data System (ADS)

Yang, Xiaodong; Yang, Hao; Dong, Yansheng; Yu, Haiyang

2014-11-01

Production management of winter wheat is more complicated than other crops since its growth period is covered all four seasons and growth environment is very complex with frozen injury, drought, insect or disease injury and others. In traditional irrigation and fertilizer management, agricultural technicians or farmers mainly make decision based on phenology, planting experience to carry out artificial fertilizer and irrigation management. For example, wheat needs more nitrogen fertilizer in jointing and booting stage by experience, then when the wheat grow to the two growth periods, the farmer will fertilize to the wheat whether it needs or not. We developed a spatial decision support system for optimizing irrigation and fertilizer measures based on WebGIS, which monitoring winter wheat growth and soil moisture content by combining a crop model, remote sensing data and wireless sensors data, then reasoning professional management schedule from expert knowledge warehouse. This system is developed by ArcIMS, IDL in server-side and JQuery, Google Maps API, ASP.NET in client-side. All computing tasks are run on server-side, such as computing 11 normal vegetable indexes (NDVI/ NDWI/ NDWI2/ NRI/ NSI/ WI/ G_SWIR/ G_SWIR2/ SPSI/ TVDI/ VSWI) and custom VI of remote sensing image by IDL; while real-time building map configuration file and generating thematic map by ArcIMS.

Less is sometimes more: a comparison of distance-control and navigated-control concepts of image-guided navigation support for surgeons.

PubMed

Luz, Maria; Manzey, Dietrich; Modemann, Susanne; Strauss, Gero

2015-01-01

Image-guided navigation (IGN) systems provide automation support of intra-operative information analysis and decision-making for surgeons. Previous research showed that navigated-control (NC) systems which represent high levels of decision-support and directly intervene in surgeons' workflow provide benefits with respect to patient safety and surgeons' physiological stress but also involve several cost effects (e.g. prolonged surgery duration, reduced secondary-task performance). It was hypothesised that less automated distance-control (DC) systems would provide a better solution in terms of human performance consequences. N = 18 surgeons performed a simulated mastoidectomy with NC, DC and without IGN assistance. Effects on surgical performance, physiological effort, workload and situation awareness (SA) were compared. As expected, DC technology had the same benefits as the NC system but also led to less unwanted side effects on surgery duration, subjective workload and SA. This suggests that IGN systems just providing information analysis support are overall more beneficial than higher automated decision-support. This study investigates human performance consequences of different concepts of IGN support for surgeons. Less automated DC systems turned out to provide advantages for patient safety and surgeons' stress similar to higher automated NC systems with, at the same time, reduced negative consequences on surgery time and subjective workload.

[Spiritual support in the spirit of current trends in the Israeli healthcare system].

PubMed

Ziv, Amitai; Talmi, Rachet; Gary-Cohen, Meirav; Chen, Wendy

2014-11-01

This editorial is in response to Bar-Sela, Bentur, Schultz and Corn's article entitled "Spiritual care in hospitals and other healthcare settings in Israel--a profession in the making", published in Harefuah in May 2014. The integration of spiritual support into hospitals marks an interesting trend in light of the current emphases in the Israeli medical system on technological advancement, financial feasibility and quantifiable quality measures. This step is evidence of the importance still attached by policy and decisionmakers to those human aspects of illness and disease, which are difficult to define and measure. "Spiritual Support" is an ancient profession based on the principle, whereby support of the spirit is considered a basic human right, in recognition of the spirit as a source of strength during times of crisis and distress. This service was introduced into the Chaim Sheba Medical Center six years ago for patients with untreatable illnesses, and through identification of commonality between their coping features and those of rehabilitation patients. It was later expanded into the orthopedic and neurological rehabilitation departments. The service is provided on an individual level for the patients and in a group formal for their caregivers. Spiritual support as an integral part of the multi-disciplinary care further ratifies the holistic approach in medical practice, as an everlasting value transcending periodical trends. The conclusion drawn is that technological advancement, the scientific approach, physical-medical treatment, emotional therapy and spiritual support can and should exist side by side to improve the welfare and coping abilities of patients dealing with adverse medical conditions.

A novel transient rotor current control scheme of a doubly-fed induction generator equipped with superconducting magnetic energy storage for voltage and frequency support

NASA Astrophysics Data System (ADS)

Shen, Yang-Wu; Ke, De-Ping; Sun, Yuan-Zhang; Daniel, Kirschen; Wang, Yi-Shen; Hu, Yuan-Chao

2015-07-01

A novel transient rotor current control scheme is proposed in this paper for a doubly-fed induction generator (DFIG) equipped with a superconducting magnetic energy storage (SMES) device to enhance its transient voltage and frequency support capacity during grid faults. The SMES connected to the DC-link capacitor of the DFIG is controlled to regulate the transient dc-link voltage so that the whole capacity of the grid side converter (GSC) is dedicated to injecting reactive power to the grid for the transient voltage support. However, the rotor-side converter (RSC) has different control tasks for different periods of the grid fault. Firstly, for Period I, the RSC injects the demagnetizing current to ensure the controllability of the rotor voltage. Then, since the dc stator flux degenerates rapidly in Period II, the required demagnetizing current is low in Period II and the RSC uses the spare capacity to additionally generate the reactive (priority) and active current so that the transient voltage capability is corroborated and the DFIG also positively responds to the system frequency dynamic at the earliest time. Finally, a small amount of demagnetizing current is provided after the fault clearance. Most of the RSC capacity is used to inject the active current to further support the frequency recovery of the system. Simulations are carried out on a simple power system with a wind farm. Comparisons with other commonly used control methods are performed to validate the proposed control method. Project supported by the National Natural Science Foundation of China (Grant No. 51307124) and the Major Program of the National Natural Science Foundation of China (Grant No. 51190105).

Collaborative Manufacturing for Small-Medium Enterprises

NASA Astrophysics Data System (ADS)

Irianto, D.

2016-02-01

Manufacturing systems involve decisions concerning production processes, capacity, planning, and control. In a MTO manufacturing systems, strategic decisions concerning fulfilment of customer requirement, manufacturing cost, and due date of delivery are the most important. In order to accelerate the decision making process, research on decision making structure when receiving order and sequencing activities under limited capacity is required. An effective decision making process is typically required by small-medium components and tools maker as supporting industries to large industries. On one side, metal small-medium enterprises are expected to produce parts, components or tools (i.e. jigs, fixture, mold, and dies) with high precision, low cost, and exact delivery time. On the other side, a metal small- medium enterprise may have weak bargaining position due to aspects such as low production capacity, limited budget for material procurement, and limited high precision machine and equipment. Instead of receiving order exclusively, a small-medium enterprise can collaborate with other small-medium enterprise in order to fulfill requirements high quality, low manufacturing cost, and just in time delivery. Small-medium enterprises can share their best capabilities to form effective supporting industries. Independent body such as community service at university can take a role as a collaboration manager. The Laboratory of Production Systems at Bandung Institute of Technology has implemented shared manufacturing systems for small-medium enterprise collaboration.

5. LAUNCH CONTROL SUPPORT BUILDING SOUTH SIDE. VIEW TO NORTHWEST. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. LAUNCH CONTROL SUPPORT BUILDING SOUTH SIDE. VIEW TO NORTHWEST. - Minuteman III ICBM Launch Control Facility November-1, 1.5 miles North of New Raymer & State Highway 14, New Raymer, Weld County, CO

Helium-Cooled Black Shroud for Subscale Cryogenic Testing

NASA Technical Reports Server (NTRS)

Tuttle, James; Jackson, Michael; DiPirro, Michael; Francis, John

2011-01-01

This shroud provides a deep-space simulating environment for testing scaled-down models of passively cooling systems for spaceflight optics and instruments. It is used inside a liquid-nitrogen- cooled vacuum chamber, and it is cooled by liquid helium to 5 K. It has an inside geometry of approximately 1.6 m diameter by 0.45 m tall. The inside surfaces of its top and sidewalls have a thermal absorptivity greater than 0.96. The bottom wall has a large central opening that is easily customized to allow a specific test item to extend through it. This enables testing of scale models of realistic passive cooling configurations that feature a very large temperature drop between the deepspace-facing cooled side and the Sun/Earth-facing warm side. This shroud has an innovative thermal closeout of the bottom wall, so that a test sample can have a hot (room temperature) side outside of the shroud, and a cold side inside the shroud. The combination of this closeout and the very black walls keeps radiated heat from the sample s warm end from entering the shroud, reflecting off the walls and heating the sample s cold end. The shroud includes 12 vertical rectangular sheet-copper side panels that are oriented in a circular pattern. Using tabs bent off from their edges, these side panels are bolted to each other and to a steel support ring on which they rest. The removable shroud top is a large copper sheet that rests on, and is bolted to, the support ring when the shroud is closed. The support ring stands on four fiberglass tube legs, which isolate it thermally from the vacuum chamber bottom. The insides of the cooper top and side panels are completely covered with 25- mm-thick aluminum honeycomb panels. This honeycomb is painted black before it is epoxied to the copper surfaces. A spiral-shaped copper tube, clamped at many different locations to the outside of the top copper plate, serves as part of the liquid helium cooling loop. Another copper tube, plumbed in a series to the top plate s tube, is clamped to the sidewall tabs where they are bolted to the support ring. Flowing liquid helium through these tubes cools the entire shroud to 5 K. The entire shroud is wrapped loosely in a layer of double-aluminized Kapton. The support ring s inner diameter is the largest possible hole through which the test item can extend into the shroud. Twelve custom-sized trapezoidal copper sheets extend inward from the support ring to within a few millimeters of the test item. Attached to the inner edge of each of these sheets is a custom-shaped strip of Kapton, which is aluminum- coated on the warm-facing (outer) side, and has thin Dacron netting attached to its cold-facing side. This Kapton rests against the test item, but the Dacron keeps it from making significant thermal contact. The result is a non-contact, radiatively reflective thermal closeout with essentially no gap through which radiation can pass. In this way, the part of the test item outside the shroud can be heated to relatively high temperatures without any radiative heat leaking to the inside.

Cascaded Quadruple Active Bridge Structures for Multilevel DC to Three-Phase AC Conversion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Brian B; Achanta, Prasanta K; Maksimovic, Dragan

This paper introduces a multilevel architecture comprised of interconnected dc to three-phase ac converter units. To enable series connected operation, each converter unit contains a quadruple active bridge (QAB) converter that provides isolation between the dc side and each of the three ac sides. Since each converter unit transfers dc-side power as constant balanced three-phase power on the ac side, this implies instantaneous input-output power balance and allows elimination of bulk capacitive energy storage. In addition to minimizing required capacitance, the proposed approach simultaneously enables simplified dc-link controllers amenable to decentralized implementation, supports bidirectional power transfer, and exhibits a modularmore » structure to enhance scalability. Isolation provided by the QAB allows a wide range of electrical configurations among multiple units in various dc-ac, ac-dc or ac-ac applications. In this paper, the focus is on series connections on the ac side to emphasize multilevel operation, and the approach is experimentally validated in a dc-ac system containing two cascaded converter units.« less

Apparatus for Hot Impact Testing of Material Specimens

NASA Technical Reports Server (NTRS)

Pawlik, Ralph J.; Choi, Sung R.

2006-01-01

An apparatus for positioning and holding material specimens is a major subsystem of a system for impact testing of the specimens at temperatures up to 1,500 C. This apparatus and the rest of the system are designed especially for hot impact testing of advanced ceramics, composites, and coating materials. The apparatus includes a retaining fixture on a rotating stage on a vertically movable cross support driven by a linear actuator. These components are located below a furnace wherein the hot impact tests are performed (see Figure 1). In preparation for a test, a specimen is mounted on the retaining fixture, then the cross support is moved upward to raise the specimen, through an opening in the bottom of the furnace, to the test position inside the furnace. On one side of the furnace there is another, relatively small opening on a direct line to the specimen. Once the specimen has become heated to the test temperature, the test is performed by using an instrumented external pressurized-gas-driven gun to shoot a projectile through the side opening at the specimen.

Compliant walker

NASA Technical Reports Server (NTRS)

Kerley, James J. (Inventor); Eklund, Wayne D. (Inventor); Crane, J. Allen (Inventor)

1992-01-01

A compliant walker is provided for humans having limited use of their legs and lower back. It includes an upright wheel frame which at least partially surrounds an upright user wearing a partial body harness. It is attached to the frame by means of cable compliant apparatus consisting of sets of cable segments and angle bracket members connected between opposite side members of the frame and adjacent side portions of the harness. Novelty is believed to exist in the combination of a wheeled frame including a side support structure, a body harness, and compliance means connecting the body harness to the side support structure for flexibility holding and supporting a person in a substantially upright position when the user sags in the frame when taking weight off the lower extremities.

System and method for laser assisted sample transfer to solution for chemical analysis

DOEpatents

Van Berkel, Gary J; Kertesz, Vilmos

2014-01-28

A system and method for laser desorption of an analyte from a specimen and capturing of the analyte in a suspended solvent to form a testing solution are described. The method can include providing a specimen supported by a desorption region of a specimen stage and desorbing an analyte from a target site of the specimen with a laser beam centered at a radiation wavelength (.lamda.). The desorption region is transparent to the radiation wavelength (.lamda.) and the sampling probe and a laser source emitting the laser beam are on opposite sides of a primary surface of the specimen stage. The system can also be arranged where the laser source and the sampling probe are on the same side of a primary surface of the specimen stage. The testing solution can then be analyzed using an analytical instrument or undergo further processing.

Determination of tube-to-tube support interaction characteristics. [PWR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haslinger, K.H.

Tube-to-tube support interaction characteristics were determined on a multi-span tube geometry representative of the hot-leg side of the C-E, System 80 steam generator design. Results will become input for an autoclave type wear test program on steam generator tubes, performed by Kraftwerk Union (KWU). Correlation of test data reported here with similar data obtained from the wear tests will be performed in an attempt to make predictions about the long-term fretting behavior of steam generator tubes.

Effect of the Crystal Environment on Side-Chain Conformational Dynamics in Cyanovirin-N Investigated through Crystal and Solution Molecular Dynamics Simulations

PubMed Central

Ahlstrom, Logan S.; Vorontsov, Ivan I.; Shi, Jun; Miyashita, Osamu

2017-01-01

Side chains in protein crystal structures are essential for understanding biochemical processes such as catalysis and molecular recognition. However, crystal packing could influence side-chain conformation and dynamics, thus complicating functional interpretations of available experimental structures. Here we investigate the effect of crystal packing on side-chain conformational dynamics with crystal and solution molecular dynamics simulations using Cyanovirin-N as a model system. Side-chain ensembles for solvent-exposed residues obtained from simulation largely reflect the conformations observed in the X-ray structure. This agreement is most striking for crystal-contacting residues during crystal simulation. Given the high level of correspondence between our simulations and the X-ray data, we compare side-chain ensembles in solution and crystal simulations. We observe large decreases in conformational entropy in the crystal for several long, polar and contacting residues on the protein surface. Such cases agree well with the average loss in conformational entropy per residue upon protein folding and are accompanied by a change in side-chain conformation. This finding supports the application of surface engineering to facilitate crystallization. Our simulation-based approach demonstrated here with Cyanovirin-N establishes a framework for quantitatively comparing side-chain ensembles in solution and in the crystal across a larger set of proteins to elucidate the effect of the crystal environment on protein conformations. PMID:28107510

Effect of the Crystal Environment on Side-Chain Conformational Dynamics in Cyanovirin-N Investigated through Crystal and Solution Molecular Dynamics Simulations.

PubMed

Ahlstrom, Logan S; Vorontsov, Ivan I; Shi, Jun; Miyashita, Osamu

2017-01-01

Side chains in protein crystal structures are essential for understanding biochemical processes such as catalysis and molecular recognition. However, crystal packing could influence side-chain conformation and dynamics, thus complicating functional interpretations of available experimental structures. Here we investigate the effect of crystal packing on side-chain conformational dynamics with crystal and solution molecular dynamics simulations using Cyanovirin-N as a model system. Side-chain ensembles for solvent-exposed residues obtained from simulation largely reflect the conformations observed in the X-ray structure. This agreement is most striking for crystal-contacting residues during crystal simulation. Given the high level of correspondence between our simulations and the X-ray data, we compare side-chain ensembles in solution and crystal simulations. We observe large decreases in conformational entropy in the crystal for several long, polar and contacting residues on the protein surface. Such cases agree well with the average loss in conformational entropy per residue upon protein folding and are accompanied by a change in side-chain conformation. This finding supports the application of surface engineering to facilitate crystallization. Our simulation-based approach demonstrated here with Cyanovirin-N establishes a framework for quantitatively comparing side-chain ensembles in solution and in the crystal across a larger set of proteins to elucidate the effect of the crystal environment on protein conformations.

What can volunteer co-providers contribute to health systems? The role of people living with HIV in the Thai paediatric HIV programme.

PubMed

Tulloch, Olivia; Taegtmeyer, Miriam; Ananworanich, Jintanat; Chasombat, Sanchai; Kosalaraksa, Pope; Theobald, Sally

2015-11-01

In Thailand people living with HIV (PLHIV) have played a major role in shaping policy and practice. They have acted as volunteer co-providers, although their potential in terms of paediatric service provision has seldom been explored from a health systems perspective. We describe the Thai paediatric HIV care system and use both demand- and supply-side perspectives to explore the impact, opportunities and challenges of PLHIV acting as volunteer co-providers. We employed qualitative methods to assess experiences and perceptions and triangulate stakeholder perspectives. Data were collected in Khon Kaen province, in the poorest Northeastern region of Thailand: three focus group discussions and two workshops (total participants n = 31) with co-providers and hospital staff; interviews with ART service-users (n = 35). Nationally, key informant interviews were conducted with policy actors (n = 20). Volunteer co-providers were found to be ideally placed to broker the link between clinic and communities for HIV infected children and played an important part in the vital psychosocial support component of HIV care. As co-providers they were recognized as having multiple roles linking and delivering services in clinics and communities. Clear emerging needs include strengthened coordination and training as well as strategies to support funding. Using motivated volunteers with a shared HIV status as co-providers for specific clinical services can contribute to strengthening health systems in Asia; they are critical players in delivering care (supply side) and being responsive to service-users needs (demand side). Co-providers blur the boundaries between these two spheres. Sustaining and optimising co-providers' contribution to health systems strengthening requires a health systems approach. Our findings help to guide policy makers and service providers on how to balance clinical priorities with psycho-social responsiveness and on how best to integrate the views and experience of volunteers into a holistic model of care. Copyright © 2014 Elsevier Ltd. All rights reserved.

SUV Rollover Test

NASA Technical Reports Server (NTRS)

Chambers, William V.

2004-01-01

The National Highway Traffic Safety Administration (NHTSA) approached NASA to evaluate vehicle rollover resistance using the High Capacity Centrifuge Facility. Testing was planned for six different sport utility vehicles. Previous methods for simulating the rollover conditions were considered to be not indicative of the true driving conditions. A more realistic gradual application of side loading could be achieved by using a centrifuge facility. A unique load measuring lower support system was designed to measure tire loading on the inboard tires and to indicate tire liftoff. This lower support system was designed to more closely emulate the actual rollover conditions. Additional design features were provided to mitigate potential safety hazards.

Hemispheric Lateralization of Motor Thresholds in Relation to Stuttering

PubMed Central

Alm, Per A.; Karlsson, Ragnhild; Sundberg, Madeleine; Axelson, Hans W.

2013-01-01

Stuttering is a complex speech disorder. Previous studies indicate a tendency towards elevated motor threshold for the left hemisphere, as measured using transcranial magnetic stimulation (TMS). This may reflect a monohemispheric motor system impairment. The purpose of the study was to investigate the relative side-to-side difference (asymmetry) and the absolute levels of motor threshold for the hand area, using TMS in adults who stutter (n = 15) and in controls (n = 15). In accordance with the hypothesis, the groups differed significantly regarding the relative side-to-side difference of finger motor threshold (p = 0.0026), with the stuttering group showing higher motor threshold of the left hemisphere in relation to the right. Also the absolute level of the finger motor threshold for the left hemisphere differed between the groups (p = 0.049). The obtained results, together with previous investigations, provide support for the hypothesis that stuttering tends to be related to left hemisphere motor impairment, and possibly to a dysfunctional state of bilateral speech motor control. PMID:24146930

7. VIEW OF REDUCTION GEARS. TRUNNION SUPPORT GIRDERS, SIDES OF ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. VIEW OF REDUCTION GEARS. TRUNNION SUPPORT GIRDERS, SIDES OF COUNTERWEIGHTS, WITH LOWER BUFFERS, LOOKING WEST FROM WEST CANAL PIER. - East Division Street Bridge, Spanning North Branch Canal at West Division Street, Chicago, Cook County, IL

3. LAUNCH CONTROL SUPPORT BUILDING NORTH SIDE AND WEST FRONT. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. LAUNCH CONTROL SUPPORT BUILDING NORTH SIDE AND WEST FRONT. VIEW TO SOUTHEAST. - Minuteman III ICBM Launch Control Facility November-1, 1.5 miles North of New Raymer & State Highway 14, New Raymer, Weld County, CO

4. LAUNCH CONTROL SUPPORT BUILDING NORTH SIDE AND EAST REAR. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. LAUNCH CONTROL SUPPORT BUILDING NORTH SIDE AND EAST REAR. VIEW TO SOUTHWEST. - Minuteman III ICBM Launch Control Facility November-1, 1.5 miles North of New Raymer & State Highway 14, New Raymer, Weld County, CO

Hubble Space Telescope (HST) above OV-103's PLB during STS-31 deployment

NASA Image and Video Library

1990-04-25

The Hubble Space Telescope (HST) is raised above the payload bay (PLB) in low hover position during STS-31 checkout and pre-deployment procedures aboard Discovery, Orbiter Vehicle (OV) 103. Stowed along the HST Support System Module (SSM) are the high gain antenna (HGA) (center) and the two solar arrays (one either side). In the background are the orbital maneuvering system (OMS) pods and the Earth's surface.

STS-31 pre-deployment checkout of the Hubble Space Telescope (HST) on OV-103

NASA Image and Video Library

1990-04-25

The Hubble Space Telescope (HST), grappled by Discovery's, Orbiter Vehicle (OV) 103's, remote manipulator system (RMS), is oriented in a 90 degree pitch position during STS-31 pre-deployment checkout procedures. The solar array (SA) panel (center) and high gain antennae (HGA) (on either side) are stowed along the Support System Module (SSM) forward shell prior to deployment. The sun highlights HST against the blackness of space.

Design of internal support structures for an inflatable lunar habitat

NASA Technical Reports Server (NTRS)

Cameron, Elizabeth A.; Duston, John A.; Lee, David D.

1990-01-01

NASA has a long range goal of constructing a fully equipped, manned lunar outpost on the near side of the moon by the year 2015. The proposed outpost includes an inflatable lunar habitat to support crews during missions longer that 12 months. A design for the internal support structures of the inflatable habitat is presented. The design solution includes material selection, substructure design, assembly plan development, and concept scale model construction. Alternate designs and design solutions for each component of the design are discussed. Alternate materials include aluminum, titanium, and reinforced polymers. Vertical support alternates include column systems, truss systems, suspension systems, and lunar lander supports. Horizontal alternates include beams, trusses, floor/truss systems, and expandable trusses. Feasibility studies on each alternate showed that truss systems and expandable trusses were the most feasible candidates for conceptual design. The team based the designs on the properties of 7075 T73 aluminum. The substructure assembly plan, minimizes assembly time and allows crews to construct the habitat without the use of EVA suits. In addition to the design solutions, the report gives conclusions and recommendations for further study of the inflatable habitat design.

Biological treatment of habitation waste streams using full scale MABRs

NASA Astrophysics Data System (ADS)

Jackson, William; Barta, Daniel J.; Morse, Audra; Christenson, Dylan; Sevanthi, Ritesh

Recycling waste water is a critical step to support sustainable long term habitation in space. Water is one of the largest contributors to life support requirements. In closed loop life support systems, membrane aerated biological reactors (MABRs) can reduce the dissolved organic carbon (DOC) and ammonia (NH3) concentration as well as decrease the pH, leading to a more stable solution with less potential to support biological growth or promote carryover of unionized ammonia as well as producing a higher quality brine. Over the last three years we have operated 3 full size MABRs ( 120L) treating a habitation type waste stream composed of urine, hygiene, and laundry water. The reactors varied in the specific surface area (260, 200, and 150 m2/m3) available for biofilm growth and gas transfer. The liquid side system was continually monitored for pH, TDS, and DO, and the influent and effluent monitored daily for DOC, TN, NOx, and NH4. The gas side system was continuously monitored for O2, CO2, and N2O in the effluent gas as well as pressure and flow rates. These systems have all demonstrated greater than 90% DOC reductions and ammonium conversion rates of 50-70% over a range of loading rates with effluent pH from 5-7.5. We have evaluated. In addition, to evaluating the impact of loading rates (10-70 l/d) we have also evaluated the impact of forced hibernation, the use of pure O2 on performance, the impact of pressurize operation to prevent de-gassing of N2 and to promote higher O2 transfer and a discontinuous feeding cycle to allow integration with desalination. Our analysis includes quantification of consumables (power and O2), waste products such as CO2 and N2O as well as solids production. Our results support the use of biological reactors to treat habitation waste streams as an alternative to the use of pretreatment and desalination alone.

Methanol sensor operated in a passive mode

DOEpatents

Ren, Xiaoming; Gottesfeld, Shimshon

2002-01-01

A sensor outputs a signal related to a concentration of methanol in an aqueous solution adjacent the sensor. A membrane electrode assembly (MEA) is included with an anode side and a cathode side. An anode current collector supports the anode side of the MEA and has a flow channel therethrough for flowing a stream of the aqueous solution and forms a physical barrier to control access of the methanol to the anode side of the MEA. A cathode current collector supports the cathode side of the MEA and is configured for air access to the cathode side of the MEA. A current sensor is connected to measure the current in a short circuit across the sensor electrodes to provide an output signal functionally related to the concentration of methanol in the aqueous solution.

Natural Characteristics of The Herringbone Gear Transmission System

NASA Astrophysics Data System (ADS)

Zhou, Jianxing; Sun, Wenlei; Cao, Li

2018-03-01

According to the structure characteristics of herringbone gear transmission, a more realistic dynamic model of the transmission system is built in consideration of the inner excitation, herringbone gears axial positioning and sliding bearing etc. The natural frequencies of the system are calculated, and the vibration mode is divided into symmetric vibration modes and asymmetric vibration modes. The time history of system dynamic force is obtained by solving the dynamic model. The effects of the connection stiffness of left and right sides of herringbone gears and axial support stiffness on natural characteristics are discussed.

FX-87 performance measurements: data-flow implementation. Technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hammel, R.T.; Gifford, D.K.

1988-11-01

This report documents a series of experiments performed to explore the thesis that the FX-87 effect system permits a compiler to schedule imperative programs (i.e., programs that may contain side-effects) for execution on a parallel computer. The authors analyze how much the FX-87 static effect system can improve the execution times of five benchmark programs on a parallel graph interpreter. Three of their benchmark programs do not use side-effects (factorial, fibonacci, and polynomial division) and thus did not have any effect-induced constraints. Their FX-87 performance was comparable to their performance in a purely functional language. Two of the benchmark programsmore » use side effects (DNA sequence matching and Scheme interpretation) and the compiler was able to use effect information to reduce their execution times by factors of 1.7 to 5.4 when compared with sequential execution times. These results support the thesis that a static effect system is a powerful tool for compilation to multiprocessor computers. However, the graph interpreter we used was based on unrealistic assumptions, and thus our results may not accurately reflect the performance of a practical FX-87 implementation. The results also suggest that conventional loop analysis would complement the FX-87 effect system« less

Loglines. March-April 2014

DTIC Science & Technology

2014-04-01

engine mechanic, selects a compressor blade to install in the core module of an F-16 jet engine. DLA Aviation has partnered with Air Force customers to...Support 9 Supporting the Fleet 14 Air Force Support 18 Beyond the Military Services 22 SERVICE TEAMS Side-by-Side Support Chemical Management Services...Marine Corps ordnance technicians load a missile at Kunsan Air Base, South Korea. Service members from the different military branches often work

System for supporting a bundled tube fuel injector within a combustor

DOE Office of Scientific and Technical Information (OSTI.GOV)

LeBegue, Jeffrey Scott; Melton, Patrick Benedict; Westmoreland, III, James Harold

A combustor includes an end cover having an outer side and an inner side, an outer barrel having a forward end that is adjacent to the inner side of the end cover and an aft end that is axially spaced from the forward end. An inner barrel is at least partially disposed concentrically within the outer barrel and is fixedly connected to the outer barrel. A fluid conduit extends downstream from the end cover. A first bundled tube fuel injector segment is disposed concentrically within the inner barrel. The bundled tube fuel injector segment includes a fuel plenum that ismore » in fluid communication with the fluid conduit and a plurality of parallel tubes that extend axially through the fuel plenum. The bundled tube fuel injector segment is fixedly connected to the inner barrel.« less

Side Effects (Management)

MedlinePlus

... cancer care is relieving side effects, called symptom management, palliative care, or supportive care. It is important ... treat them. To learn about the symptoms and management of the long-term side effects of cancer ...

Acoustic suspension system

NASA Technical Reports Server (NTRS)

Lee, M. C.; Wang, T. G. (Inventor)

1983-01-01

An acoustic levitation system is described, with single acoustic source and a small reflector to stably levitate a small object while the object is processed as by coating or heating it. The system includes a concave acoustic source which has locations on opposite sides of its axis that vibrate towards and away from a focal point to generate a converging acoustic field. A small reflector is located near the focal point, and preferably slightly beyond it, to create an intense acoustic field that stably supports a small object near the reflector. The reflector is located about one-half wavelength from the focal point and is concavely curved to a radius of curvature (L) of about one-half the wavelength, to stably support an object one-quarter wavelength (N) from the reflector.

Cross Support Transfer Service (CSTS) Framework Library

NASA Technical Reports Server (NTRS)

Ray, Timothy

2014-01-01

Within the Consultative Committee for Space Data Systems (CCSDS), there is an effort to standardize data transfer between ground stations and control centers. CCSDS plans to publish a collection of transfer services that will each address the transfer of a particular type of data (e.g., tracking data). These services will be called Cross Support Transfer Services (CSTSs). All of these services will make use of a common foundation that is called the CSTS Framework. This library implements the User side of the CSTS Framework. "User side" means that the library performs the role that is typically expected of the control center. This library was developed in support of the Goddard Data Standards program. This technology could be applicable for control centers, and possibly for use in control center simulators needed to test ground station capabilities. The main advantages of this implementation are its flexibility and simplicity. It provides the framework capabilities, while allowing the library user to provide a wrapper that adapts the library to any particular environment. The main purpose of this implementation was to support the inter-operability testing required by CCSDS. In addition, it is likely that the implementation will be useful within the Goddard mission community (for use in control centers).

Protein-Protein Interaction Network and Gene Ontology

NASA Astrophysics Data System (ADS)

Choi, Yunkyu; Kim, Seok; Yi, Gwan-Su; Park, Jinah

Evolution of computer technologies makes it possible to access a large amount and various kinds of biological data via internet such as DNA sequences, proteomics data and information discovered about them. It is expected that the combination of various data could help researchers find further knowledge about them. Roles of a visualization system are to invoke human abilities to integrate information and to recognize certain patterns in the data. Thus, when the various kinds of data are examined and analyzed manually, an effective visualization system is an essential part. One instance of these integrated visualizations can be combination of protein-protein interaction (PPI) data and Gene Ontology (GO) which could help enhance the analysis of PPI network. We introduce a simple but comprehensive visualization system that integrates GO and PPI data where GO and PPI graphs are visualized side-by-side and supports quick reference functions between them. Furthermore, the proposed system provides several interactive visualization methods for efficiently analyzing the PPI network and GO directedacyclic- graph such as context-based browsing and common ancestors finding.

Investigation of excitation control for wind-turbine generator stability

NASA Technical Reports Server (NTRS)

Gebben, V. D.

1977-01-01

High speed horizontal axis wind turbine generators with blades on the downwind side of the support tower require special design considerations to handle disturbances introduced by the flow wake behind the tower. Experiments and analytical analyses were made to determine benefits that might be obtained by using the generator exciter to provide system damping for reducing power fluctuations.

Reliability and validity of pendulum test measures of spasticity obtained with the Polhemus tracking system from patients with chronic stroke

PubMed Central

Bohannon, Richard W; Harrison, Steven; Kinsella-Shaw, Jeffrey

2009-01-01

Background Spasticity is a common impairment accompanying stroke. Spasticity of the quadriceps femoris muscle can be quantified using the pendulum test. The measurement properties of pendular kinematics captured using a magnetic tracking system has not been studied among patients who have experienced a stroke. Therefore, this study describes the test-retest reliability and known groups and convergent validity of the pendulum test measures obtained with the Polhemus tracking system. Methods Eight patients with chronic stroke underwent pendulum tests with their affected and unaffected lower limbs, with and without the addition of a 2.2 kg cuff weight at the ankle, using the Polhemus magnetic tracking system. Also measured bilaterally were knee resting angles, Ashworth scores (grades 0–4) of quadriceps femoris muscles, patellar tendon (knee jerk) reflexes (grades 0–4), and isometric knee extension force. Results Three measures obtained from pendular traces of the affected side were reliable (intraclass correlation coefficient ≥ .844). Known groups validity was confirmed by demonstration of a significant difference in the measurements between sides. Convergent validity was supported by correlations ≥ .57 between pendulum test measures and other measures reflective of spasticity. Conclusion Pendulum test measures obtained with the Polhemus tracking system from the affected side of patients with stroke have good test-retest reliability and both known groups and convergent validity. PMID:19642989

Reliability and validity of pendulum test measures of spasticity obtained with the Polhemus tracking system from patients with chronic stroke.

PubMed

Bohannon, Richard W; Harrison, Steven; Kinsella-Shaw, Jeffrey

2009-07-30

Spasticity is a common impairment accompanying stroke. Spasticity of the quadriceps femoris muscle can be quantified using the pendulum test. The measurement properties of pendular kinematics captured using a magnetic tracking system has not been studied among patients who have experienced a stroke. Therefore, this study describes the test-retest reliability and known groups and convergent validity of the pendulum test measures obtained with the Polhemus tracking system. Eight patients with chronic stroke underwent pendulum tests with their affected and unaffected lower limbs, with and without the addition of a 2.2 kg cuff weight at the ankle, using the Polhemus magnetic tracking system. Also measured bilaterally were knee resting angles, Ashworth scores (grades 0-4) of quadriceps femoris muscles, patellar tendon (knee jerk) reflexes (grades 0-4), and isometric knee extension force. Three measures obtained from pendular traces of the affected side were reliable (intraclass correlation coefficient > or = .844). Known groups validity was confirmed by demonstration of a significant difference in the measurements between sides. Convergent validity was supported by correlations > or = .57 between pendulum test measures and other measures reflective of spasticity. Pendulum test measures obtained with the Polhemus tracking system from the affected side of patients with stroke have good test-retest reliability and both known groups and convergent validity.

Toward server-side, high performance climate change data analytics in the Earth System Grid Federation (ESGF) eco-system

NASA Astrophysics Data System (ADS)

Fiore, Sandro; Williams, Dean; Aloisio, Giovanni

2016-04-01

In many scientific domains such as climate, data is often n-dimensional and requires tools that support specialized data types and primitives to be properly stored, accessed, analysed and visualized. Moreover, new challenges arise in large-scale scenarios and eco-systems where petabytes (PB) of data can be available and data can be distributed and/or replicated (e.g., the Earth System Grid Federation (ESGF) serving the Coupled Model Intercomparison Project, Phase 5 (CMIP5) experiment, providing access to 2.5PB of data for the Intergovernmental Panel on Climate Change (IPCC) Fifth Assessment Report (AR5). Most of the tools currently available for scientific data analysis in the climate domain fail at large scale since they: (1) are desktop based and need the data locally; (2) are sequential, so do not benefit from available multicore/parallel machines; (3) do not provide declarative languages to express scientific data analysis tasks; (4) are domain-specific, which ties their adoption to a specific domain; and (5) do not provide a workflow support, to enable the definition of complex "experiments". The Ophidia project aims at facing most of the challenges highlighted above by providing a big data analytics framework for eScience. Ophidia provides declarative, server-side, and parallel data analysis, jointly with an internal storage model able to efficiently deal with multidimensional data and a hierarchical data organization to manage large data volumes ("datacubes"). The project relies on a strong background of high performance database management and OLAP systems to manage large scientific data sets. It also provides a native workflow management support, to define processing chains and workflows with tens to hundreds of data analytics operators to build real scientific use cases. With regard to interoperability aspects, the talk will present the contribution provided both to the RDA Working Group on Array Databases, and the Earth System Grid Federation (ESGF) Compute Working Team. Also highlighted will be the results of large scale climate model intercomparison data analysis experiments, for example: (1) defined in the context of the EU H2020 INDIGO-DataCloud project; (2) implemented in a real geographically distributed environment involving CMCC (Italy) and LLNL (US) sites; (3) exploiting Ophidia as server-side, parallel analytics engine; and (4) applied on real CMIP5 data sets available through ESGF.

Advanced Supported Liquid Membranes for Carbon Dioxide Control in Cabin Applications

NASA Technical Reports Server (NTRS)

Wickham, David T.; Gleason, Kevin J.; Engel, Jeffrey R.; Chullen, Cinda

2016-01-01

The development of new, robust, life support systems is critical to NASA's continued progress in space exploration. One vital function is maintaining the carbon dioxide (CO2) concentration in the cabin at levels that do not impair the health or performance of the crew. The CO2 removal assembly (CDRA) is the current CO2 control technology on-board the International Space Station (ISS). Although the CDRA has met the needs of the ISS to date, the repeated cycling of the molecular sieve sorbent causes it to break down into small particles that clog filters or generate dust in the cabin. This reduces reliability and increases maintenance requirements. Another approach that has potential advantages over the current system is a membrane that separates CO2 from air. In this approach, cabin air contacts one side of the membrane while other side of the membrane is maintained at low pressure to create a driving force for CO2 transport across the membrane. In this application, the primary power requirement is for the pump that creates the low pressure and then pumps the CO2 to the oxygen recovery system. For such a membrane to be practical, it must have high CO2 permeation rate and excellent selectivity for CO2 over air. Unfortunately, conventional gas separation membranes do not have adequate CO2 permeability and selectivity to meet the needs of this application. However, the required performance could be obtained with a supported liquid membrane (SLM), which consists of a microporous material filled with a liquid that selectively reacts with CO2 over air. In a recently completed Phase II SBIR project, Reaction Systems, Inc. fabricated an SLM that is very close to meeting permeability and selectivity objectives for use in the advanced space suit portable life support system. This paper describes work carried out to evaluate its potential for use in spacecraft cabin application.

Advanced Supported Liquid Membranes for Carbon Dioxide Control in Cabin Applications

NASA Technical Reports Server (NTRS)

Wickham, David T.; Gleason, Kevin J.; Engel, Jeffrey R.; Chullen, Cinda

2016-01-01

The development of new, robust, life support systems is critical to NASA's continued progress in space exploration. One vital function is maintaining the carbon dioxide (CO2) concentration in the cabin at levels that do not impair the health or performance of the crew. The carbon dioxide removal assembly (CDRA) is the current CO2 control technology on-board the International Space Station (ISS). Although the CDRA has met the needs of the ISS to date, the repeated cycling of the molecular sieve sorbent causes it to break down into small particles that clog filters or generate dust in the cabin. This reduces reliability and increases maintenance requirements. Another approach that has potential advantages over the current system is a membrane that separates CO2 from air. In this approach, cabin air contacts one side of the membrane while other side of the membrane is maintained at low pressure to create a driving force for CO2 transport across the membrane. In this application, the primary power requirement is for the pump that creates the low pressure and then pumps the CO2 to the oxygen recovery system. For such a membrane to be practical, it must have high CO2 permeation rate and excellent selectivity for CO2 over air. Unfortunately, conventional gas separation membranes do not have adequate CO2 permeability and selectivity to meet the needs of this application. However, the required performance could be obtained with a supported liquid membrane (SLM), which consists of a microporous material filled with a liquid that selectively reacts with CO2 over air. In a recently completed Phase II SBIR project, Reaction Systems, Inc. fabricated an SLM that is very close to meeting permeability and selectivity objectives for use in the Portable Life Support System (PLSS). This paper describes work carried out to evaluate its potential for use in the cabin.

Drug side effect extraction from clinical narratives of psychiatry and psychology patients

PubMed Central

Kocher, Jean-Pierre A; Chute, Christopher G; Savova, Guergana K

2011-01-01

Objective To extract physician-asserted drug side effects from electronic medical record clinical narratives. Materials and methods Pattern matching rules were manually developed through examining keywords and expression patterns of side effects to discover an individual side effect and causative drug relationship. A combination of machine learning (C4.5) using side effect keyword features and pattern matching rules was used to extract sentences that contain side effect and causative drug pairs, enabling the system to discover most side effect occurrences. Our system was implemented as a module within the clinical Text Analysis and Knowledge Extraction System. Results The system was tested in the domain of psychiatry and psychology. The rule-based system extracting side effects and causative drugs produced an F score of 0.80 (0.55 excluding allergy section). The hybrid system identifying side effect sentences had an F score of 0.75 (0.56 excluding allergy section) but covered more side effect and causative drug pairs than individual side effect extraction. Discussion The rule-based system was able to identify most side effects expressed by clear indication words. More sophisticated semantic processing is required to handle complex side effect descriptions in the narrative. We demonstrated that our system can be trained to identify sentences with complex side effect descriptions that can be submitted to a human expert for further abstraction. Conclusion Our system was able to extract most physician-asserted drug side effects. It can be used in either an automated mode for side effect extraction or semi-automated mode to identify side effect sentences that can significantly simplify abstraction by a human expert. PMID:21946242

Intelligent command and control systems for satellite ground operations

NASA Technical Reports Server (NTRS)

Mitchell, Christine M.

1994-01-01

The Georgia Tech portion of the Intelligent Control Center project includes several complementary activities. Two major activities entail thesis level research; the other activities are either support activities or preliminary explorations (e.g., task analyses) to support the research. The first research activity is the development of principles for the design of active interfaces to support monitoring during real-time supports. It is well known that as the operator's task becomes less active, i.e., more monitoring and less active control, there is concern that the operator will be less involved and less able to rapidly identify anomalous or failure situations. The research project to design active monitoring interfaces is an attempt to remediate this undesirable side-effect of increasingly automated control systems that still depend ultimately on operator supervision. The second research activity is the exploration of the use of case-based reasoning as a way to accumulate operator experience and make it available in computational form.

Development of a complex experimental system for controlled ecological life support technique

NASA Astrophysics Data System (ADS)

Guo, S.; Tang, Y.; Zhu, J.; Wang, X.; Feng, H.; Ai, W.; Qin, L.; Deng, Y.

A complex experimental system for controlled ecological life support technique can be used as a test platform for plant-man integrated experiments and material close-loop experiments of the controlled ecological life support system CELSS Based on lots of plan investigation plan design and drawing design the system was built through the steps of processing installation and joined debugging The system contains a volume of about 40 0m 3 its interior atmospheric parameters such as temperature relative humidity oxygen concentration carbon dioxide concentration total pressure lighting intensity photoperiod water content in the growing-matrix and ethylene concentration are all monitored and controlled automatically and effectively Its growing system consists of two rows of racks along its left-and-right sides separately and each of which holds two up-and-down layers eight growing beds hold a total area of about 8 4m 2 and their vertical distance can be adjusted automatically and independently lighting sources consist of both red and blue light-emitting diodes Successful development of the test platform will necessarily create an essential condition for next large-scale integrated study of controlled ecological life support technique

STS-31 pre-deployment checkout of the Hubble Space Telescope (HST) on OV-103

NASA Image and Video Library

1990-04-25

View taken through overhead window W7 aboard Discovery, Orbiter Vehicle (OV) 103, shows the Hubble Space Telescope (HST) grappled by the remote manipulator system (RMS) and held in a 90 degree pitch position against the blackness of space. The solar array (SA) panel (center) and the high gain antennae (HGA) (on either side) are visible along the Support System Module (SSM) forward shell prior to deployment during STS-31.

Hubble Space Telescope (HST) grappled by OV-103's RMS during STS-31 checkout

NASA Image and Video Library

1990-04-25

The Hubble Space Telescope (HST), grappled by Discovery's, Orbiter Vehicle (OV) 103's, remote manipulator system (RMS), is held in a pre-deployment position. During STS-31 checkout procedures, the solar array (SA) panels and the high gain antennae (HGA) will be deployed. The starboard SA (center) and the two HGA are stowed along side the Support System Module (SSM) forward shell. The sun highlights HST against the blackness of space.

Saturn Apollo Program

NASA Image and Video Library

1968-12-17

Apollo 8 crew members paused before the mission simulator during training for the first manned lunar orbital mission. Frank Borman, commander; James Lovell, Command Module (CM) pilot; and William Anders, Lunar Module (LM) pilot , were also the first humans to launch aboard the massive Saturn V space vehicle. Lift off occurred on December 21, 1968 and returned safely to Earth on December 27, 1968. The mission achieved operational experience and tested the Apollo command module systems, including communications, tracking, and life-support, in cis-lunar space and lunar orbit, and allowed evaluation of crew performance on a lunar orbiting mission. The crew photographed the lunar surface, both far side and near side, obtaining information on topography and landmarks as well as other scientific information necessary for future Apollo landings. All systems operated within allowable parameters and all objectives of the mission were achieved.

The PsyLOG mobile application: development of a tool for the assessment and monitoring of side effects of psychotropic medication.

PubMed

Kuzman, Martina Rojnic; Andlauer, Olivier; Burmeister, Kai; Dvoracek, Boris; Lencer, Rebekka; Koelkebeck, Katja; Nawka, Alexander; Riese, Florian

2017-06-01

Mobile health interventions are regarded as affordable and accessible tools that can enhance standard psychiatric care. As part of the mHealth Psycho-Educational Intervention Versus Antipsychotic-Induced Side Effects (mPIVAS) project (www.psylog.eu), we developed the mobile application "PsyLOG" based on mobile "smartphone" technology to monitor antipsychotic-induced side effects. The aim of this paper is to describe the rationale and development of the PsyLOG and its clinical use. The PsyLOG application runs on smartphones with Android operating system. The application is currently available in seven languages (Croatian, Czech, English, French, German, Japanese and Serbian). It consists of several categories: "My Drug Effects", "My Life Styles", "My Charts", "My Medication", "My Strategies", "My Supporters", "Settings" and "About". The main category "My Drug Effects" includes a list of 30 side effects with the possibility to add three additional side effects. Side effects are each accompanied by an appropriate description and the possibility to rate its severity on a visual analogue scale from 0-100%. The PsyLOG application is intended to enhance the link between patients and mental health professionals, serving as a tool that more objectively monitors side-effects over certain periods of time. To the best of our knowledge, no such applications have so far been developed for patients taking antipsychotic medication or for their therapists.

Tailoring the Employment of Offshore Wind Turbine Support Structure Load Mitigation Controllers

NASA Astrophysics Data System (ADS)

Shrestha, Binita; Kühn, Martin

2016-09-01

The currently available control concepts to mitigate aerodynamic and hydrodynamic induced support structure loads reduce either fore-aft or side-to-side damage under certain operational conditions. The load reduction is achieved together with an increase in loads in other components of the turbine e.g. pitch actuators or drive train, increasing the risk of unscheduled maintenance. The main objective of this paper is to demonstrate a methodology for reduction of support structure damage equivalent loads (DEL) in fore-aft and side-to-side directions using already available control concepts. A multi-objective optimization problem is formulated to minimize the DELs, while limiting the collateral effects of the control algorithms for load reduction. The optimization gives trigger values of sea state condition for the activation or deactivation of certain control concepts. As a result, by accepting the consumption of a small fraction of the load reserve in the design load envelope of other turbine components, a considerable reduction of the support structure loads is facilitated.

A Reusable Design for Precision Lunar Landing Systems

NASA Technical Reports Server (NTRS)

Fuhrman, Linda; Brand, Timothy; Fill, Tom; Norris, Lee; Paschall, Steve

2005-01-01

The top-level architecture to accomplish NASA's Vision for Space Exploration is to use Lunar missions and systems not just as an end in themselves, but also as testbeds for the more ambitious goals of Human Mars Exploration (HME). This approach means that Lunar missions and systems are most likely going to be targeted for (Lunar) polar missions, and also for long-duration (months) surface stays. This overacting theme creates basic top-level requirements for any next-generation lander system: 1) Long duration stays: a) Multiple landers in close proximity; b) Pinpoint landings for "surface rendezvous"; c) Autonomous landing of pre-positioned assets; and d) Autonomous Hazard Detection and Avoidance. 2) Polar and deep-crater landings (dark); 3) Common/extensible systems for Moon and Mars, crew and cargo. These requirements pose challenging technology and capability needs. Compare and contrast: 4) Apollo: a) 1 km landing accuracy; b) Lunar near-side (well imaged and direct-to-Earth com. possible); c) Lunar equatorial (landing trajectories offer best navigation support from Earth); d) Limited lighting conditions; e) Significant ground-in-the-loop operations; 5) Lunar Access: a) 10-100m landing precision; b) "Anywhere" access includes polar (potentially poor nav. support from Earth) and far side (poor gravity and imaging; no direct-to-Earth com); c) "Anytime" access includes any lighting condition (including dark); d) Full autonomous landing capability; e) Extensible design for tele-operation or operator-in-the-loop; and f) Minimal ground support to reduce operations costs. The Lunar Access program objectives, therefore, are to: a) Develop a baseline Lunar Precision Landing System (PLS) design to enable pinpoint "anywhere, anytime" landings; b) landing precision 10m-100m; c) Any LAT, LON; and d) Any lighting condition; This paper will characterize basic features of the next generation Lunar landing system, including trajectory types, sensor suite options and a reference system architecture.

Congenital Diaphragmatic Hernia: The Side of Diaphragmatic Defect and Associated Nondiaphragmatic Malformations.

PubMed

Grizelj, Ruža; Bojanić, Katarina; Vuković, Jurica; Weingarten, Toby N; Schroeder, Darrell R; Sprung, Juraj

2017-07-01

Background  Congenital diaphragmatic hernia (CDH) has different clinical presentations depending on whether it is right sided (R-CDH) or left sided (L-CDH). Some have suggested that L-CDH and R-CDH may represent different syndromic phenotypes. This theory would be indirectly supported if different nondiaphragmatic anomalies were associated with laterality. We assessed whether CDH laterality is associated with specific types of nondiaphragmatic anomalies. Methods  Cases of CDH were retrospectively identified from five centers, and associated congenital anomalies, prenatal diagnosis, demographics, birth characteristics, and side of the CDH were analyzed. CDH characteristics were summarized according to the absence (isolated) or presence (complex) of nondiaphragmatic malformations. Results  Among 228 neonates with CDH, 140 (61%) had isolated CDH and 88 (39%) had complex CDH. Complex CDH was significantly associated with being small for gestational age (odds ratio [95% confidence interval, CI]: 8.3 [1.9-35.7]; p  = 0.005) and having L-CDH (odds ratio [95% CI]: 3.6 [1.5-8.9]; p  = 0.005). The overall proportion with anomalies differed by side (42% for L-CDH, 23% for R-CDH; p  = 0.02), but the rates of anomalies in specific organ systems did not differ. Conclusion  The rate of associated nondiaphragmatic anomalies by specific organ system did not differ between L-CDH and R-CDH, which suggests that they represent the same phenotypic entity. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Broadband network on-line data acquisition system with web based interface for control and basic analysis

NASA Astrophysics Data System (ADS)

Polkowski, Marcin; Grad, Marek

2016-04-01

Passive seismic experiment "13BB Star" is operated since mid 2013 in northern Poland and consists of 13 broadband seismic stations. One of the elements of this experiment is dedicated on-line data acquisition system comprised of both client (station) side and server side modules with web based interface that allows monitoring of network status and provides tools for preliminary data analysis. Station side is controlled by ARM Linux board that is programmed to maintain 3G/EDGE internet connection, receive data from digitizer, send data do central server among with additional auxiliary parameters like temperatures, voltages and electric current measurements. Station side is controlled by set of easy to install PHP scripts. Data is transmitted securely over SSH protocol to central server. Central server is a dedicated Linux based machine. Its duty is receiving and processing all data from all stations including auxiliary parameters. Server side software is written in PHP and Python. Additionally, it allows remote station configuration and provides web based interface for user friendly interaction. All collected data can be displayed for each day and station. It also allows manual creation of event oriented plots with different filtering abilities and provides numerous status and statistic information. Our solution is very flexible and easy to modify. In this presentation we would like to share our solution and experience. National Science Centre Poland provided financial support for this work via NCN grant DEC-2011/02/A/ST10/00284.

Acetylcholinesterase inhibitors for electroconvulsive therapy-induced cognitive side effects: a systematic review.

PubMed

Henstra, Marieke J; Jansma, Elise P; van der Velde, Nathalie; Swart, Eleonora L; Stek, Max L; Rhebergen, Didi

2017-05-01

Electroconvulsive therapy (ECT) is an effective treatment for severe late-life depression; however, ECT-induced cognitive side effects frequently occur. The cholinergic system is thought to play an important role in the pathogenesis. We systematically reviewed the evidence for acetylcholinesterase inhibitors (Ache-I) to prevent or reduce ECT-induced cognitive side effects. A systematic search was performed in Pubmed, EMBASE, PsychINFO, and the Cochrane database to identify clinical trials investigating the effect of Ache-I on ECT-induced cognitive side effects. Key search terms included all synonyms for ECT and Ache-I. Risk of bias assessment was conducted by using the Cochrane Collaboration's tool. Five clinical trials were eligible for inclusion. All studies focused on cognitive functioning as primary endpoint, but assessment of cognitive functioning varied widely in time point of assessment and in cognitive tests that were used. There was also great variety in study medication, route and time of administration and dosages, duration of drug administration, and ECT techniques. Finally, only two out of five studies were considered at low risk of bias. Despite the aforementioned shortcomings, without exception, all studies demonstrated significantly better cognitive performance in individuals treated with Ache-I. Despite large heterogeneity in studies, Ache-I appear to have beneficial effects on ECT-induced cognitive side effects, supporting an association with the cholinergic system in ECT-induced cognitive impairment. Methodological sound studies controlling for putative confounders are warranted. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

Improvements to Autoplot's HAPI Support

NASA Astrophysics Data System (ADS)

Faden, J.; Vandegriff, J. D.; Weigel, R. S.

2017-12-01

Autoplot handles data from a variety of data servers. These servers communicate data in different forms, each somewhat different in capabilities and each needing new software to interface. The Heliophysics Application Programmer's Interface (HAPI) attempts to ease this by providing a standard target for clients and servers to meet. Autoplot fully supports reading data from HAPI servers, and support continues to improve as the HAPI server spec matures. This collaboration has already produced robust clients and documentation which would be expensive for groups creating their own protocol. For example, client-side data caching is introduced where Autoplot maintains a cache of data for performance and off-line use. This is a feature we considered for previous data systems, but we could never afford the time to study and implement this carefully. Also, Autoplot itself can be used as a server, making the data it can read and the results of its processing available to other data systems. Autoplot use with other data transmission systems is reviewed as well, outlining features of each system.

Benefits of remote real-time side-effect monitoring systems for patients receiving cancer treatment.

PubMed

Kofoed, Sarah; Breen, Sibilah; Gough, Karla; Aranda, Sanchia

2012-03-05

In Australia, the incidence of cancer diagnoses is rising along with an aging population. Cancer treatments, such as chemotherapy, are increasingly being provided in the ambulatory care setting. Cancer treatments are commonly associated with distressing and serious side-effects and patients often struggle to manage these themselves without specialized real-time support. Unlike chronic disease populations, few systems for the remote real-time monitoring of cancer patients have been reported. However, several prototype systems have been developed and have received favorable reports. This review aimed to identify and detail systems that reported statistical analyses of changes in patient clinical outcomes, health care system usage or health economic analyses. Five papers were identified that met these criteria. There was wide variation in the design of the monitoring systems in terms of data input method, clinician alerting and response, groups of patients targeted and clinical outcomes measured. The majority of studies had significant methodological weaknesses. These included no control group comparisons, small sample sizes, poor documentation of clinical interventions or measures of adherence to the monitoring systems. In spite of the limitations, promising results emerged in terms of improved clinical outcomes (e.g. pain, depression, fatigue). Health care system usage was assessed in two papers with inconsistent results. No studies included health economic analyses. The diversity in systems described, outcomes measured and methodological issues all limited between-study comparisons. Given the acceptability of remote monitoring and the promising outcomes from the few studies analyzing patient or health care system outcomes, future research is needed to rigorously trial these systems to enable greater patient support and safety in the ambulatory setting.

Benefits of remote real-time side-effect monitoring systems for patients receiving cancer treatment

PubMed Central

Kofoed, Sarah; Breen, Sibilah; Gough, Karla; Aranda, Sanchia

2012-01-01

In Australia, the incidence of cancer diagnoses is rising along with an aging population. Cancer treatments, such as chemotherapy, are increasingly being provided in the ambulatory care setting. Cancer treatments are commonly associated with distressing and serious side-effects and patients often struggle to manage these themselves without specialized real-time support. Unlike chronic disease populations, few systems for the remote real-time monitoring of cancer patients have been reported. However, several prototype systems have been developed and have received favorable reports. This review aimed to identify and detail systems that reported statistical analyses of changes in patient clinical outcomes, health care system usage or health economic analyses. Five papers were identified that met these criteria. There was wide variation in the design of the monitoring systems in terms of data input method, clinician alerting and response, groups of patients targeted and clinical outcomes measured. The majority of studies had significant methodological weaknesses. These included no control group comparisons, small sample sizes, poor documentation of clinical interventions or measures of adherence to the monitoring systems. In spite of the limitations, promising results emerged in terms of improved clinical outcomes (e.g. pain, depression, fatigue). Health care system usage was assessed in two papers with inconsistent results. No studies included health economic analyses. The diversity in systems described, outcomes measured and methodological issues all limited between-study comparisons. Given the acceptability of remote monitoring and the promising outcomes from the few studies analyzing patient or health care system outcomes, future research is needed to rigorously trial these systems to enable greater patient support and safety in the ambulatory setting. PMID:25992209

Optical antenna gain. III - The effect of secondary element support struts on transmitter gain

NASA Technical Reports Server (NTRS)

Klein, B. J.; Degnan, J. J.

1976-01-01

The effect of a secondary-element spider support structure on optical antenna transmitter gain is analyzed. An expression describing the influence of the struts on the axial gain, in both the near and far fields, is derived as a function of the number of struts and their width. It is found that, for typical systems, the struts degrade the on-axis gain by less than 0.4 dB, and the first side-lobe level is not increased significantly. Contour plots have also been included to show the symmetry of the far-field distributions for three- and four-support members.

Fuel cell with interdigitated porous flow-field

DOEpatents

Wilson, Mahlon S.

1997-01-01

A polymer electrolyte membrane (PEM) fuel cell is formed with an improved system for distributing gaseous reactants to the membrane surface. A PEM fuel cell has an ionic transport membrane with opposed catalytic surfaces formed thereon and separates gaseous reactants that undergo reactions at the catalytic surfaces of the membrane. The fuel cell may also include a thin gas diffusion layer having first and second sides with a first side contacting at least one of the catalytic surfaces. A macroporous flow-field with interdigitated inlet and outlet reactant channels contacts the second side of the thin gas diffusion layer for distributing one of the gaseous reactants over the thin gas diffusion layer for transport to an adjacent one of the catalytic surfaces of the membrane. The porous flow field may be formed from a hydrophilic material and provides uniform support across the backside of the electrode assembly to facilitate the use of thin backing layers.

Fuel cell with interdigitated porous flow-field

DOEpatents

Wilson, M.S.

1997-06-24

A polymer electrolyte membrane (PEM) fuel cell is formed with an improved system for distributing gaseous reactants to the membrane surface. A PEM fuel cell has an ionic transport membrane with opposed catalytic surfaces formed thereon and separates gaseous reactants that undergo reactions at the catalytic surfaces of the membrane. The fuel cell may also include a thin gas diffusion layer having first and second sides with a first side contacting at least one of the catalytic surfaces. A macroporous flow-field with interdigitated inlet and outlet reactant channels contacts the second side of the thin gas diffusion layer for distributing one of the gaseous reactants over the thin gas diffusion layer for transport to an adjacent one of the catalytic surfaces of the membrane. The porous flow field may be formed from a hydrophilic material and provides uniform support across the backside of the electrode assembly to facilitate the use of thin backing layers. 9 figs.

Skylab

NASA Image and Video Library

1972-01-01

This photograph depicts the flight article of the Airlock Module (AM) Flight Article being mated to the Fixed Airlock Shroud and aligned in a clean room of the McDornell Douglas Plant in St. Louis, Missouri. The AM enabled crew members to conduct extravehicular activities outside Skylab as required for experiment support. Separated from the Workshop and the Multiple Docking Adapter by doors, the AM could be evacuated for egress or ingress of a space-suited astronaut through a side hatch. Oxygen and nitrogen storage tanks needed for Skylab's life support system were mounted on the external truss work of the AM. Major components in the AM included Skylab's electric power control and distribution station, environmental control system, communication system, and data handling and recording systems. The Marshall Space Flight Center was responsible for the design and development of the Skylab hardware and experiment management.

East side, showing ruin of brownstone column capital that originally ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

East side, showing ruin of brownstone column capital that originally supported the east side portico, a feature that was destroyed in the 1886 earthquake - William Ravenel House, 13 East Battery Street, Charleston, Charleston County, SC

Side effect profile similarities shared between antidepressants and immune-modulators reveal potential novel targets for treating major depressive disorders.

PubMed

Sun, Yu; Narayan, Vaibhav A; Wittenberg, Gayle M

2016-10-21

Side effects, or the adverse effects of drugs, contain important clinical phenotypic information that may be useful in predicting novel or unknown targets of a drug. It has been suggested that drugs with similar side-effect profiles may share common targets. The diagnostic class, Major Depressive Disorder, is increasingly viewed as being comprised of multiple depression subtypes with different biological root causes. One 'type' of depression generating substantial interest today focuses on patients with high levels of inflammatory burden, indicated by elevated levels of C-reactive proteins (CRP) and pro-inflammatory cytokines such as interleukin 6 (IL-6). It has been suggested that drugs targeting the immune system may have beneficial effect on this subtype of depressed patients, and several studies are underway to test this hypothesis directly. However, patients have been treated with both anti-inflammatory and antidepressant compounds for decades. It may be possible to exploit similarities in clinical readouts to better understand the antidepressant effects of immune-related drugs. Here we explore the space of approved drugs by comparing the drug side effect profiles of known antidepressants and drugs targeting the immune system, and further examine the findings by comparing the human cell line expression profiles induced by them with those induced by antidepressants. We found 7 immune-modulators and 14 anti-inflammatory drugs sharing significant side effect profile similarities with antidepressants. Five of the 7 immune modulators share most similar side effect profiles with antidepressants that modulate dopamine release and/or uptake. In addition, the immunosuppressant rapamycin and the glucocorticoid alclometasone induces transcriptional changes similar to multiple antidepressants. These findings suggest that some antidepressants and some immune-related drugs may affect common molecular pathways. Our findings support the idea that certain medications aimed at the immune system may be helpful in relieving depressive symptoms, and suggest that it may be of value to test immune-modulators for antidepressant-like activity in future proof-of-concept studies.

Environmental Support for High Frequency Acoustic Measurements at NOSC (Naval Ocean Systems Center) Oceanographic Tower, 26 April-7 May 1982. Part 1. Sediment Geoacoustic Properties

DTIC Science & Technology

1983-06-01

surrounding the tripod (cores 14, 15, 16) were moderately to moderately well-sorted, fine-skewed, platykurtic to mesokurtic coarse grained sands, The...side of the interface. mrt Sediments throughout the 18 cm length of core 7 were moderately sorted, very finely-skewed, platykurtic to mesokurtic

Orbiter Water Dump Nozzles Redesign Lessons Learned

NASA Technical Reports Server (NTRS)

Rotter, Hank

2017-01-01

Hank Rotter, NASA Technical Fellow for Environmental Control and Life Support System, will provide the causes and lessons learned for the two Space Shuttle Orbiter water dump icicles that formed on the side of the Orbiter. He will present the root causes and the criticality of these icicles, along with the redesign of the water dump nozzles and lessons learned during the redesign phase.

Fractal Stiffening

NASA Technical Reports Server (NTRS)

Harper, David William (Inventor)

2017-01-01

A structural support having fractal-stiffening and method of fabricating the support is presented where an optimized location of at least three nodes is predetermined prior to fabricating the structural support where a first set of webs is formed on one side of the support and joined to the nodes to form a first pocket region. A second set of webs is formed within the first pocket region forming a second pocket region where the height of the first set of webs extending orthogonally from the side of the support is greater than the second set of webs extending orthogonally from the support.

Molten metal injector system and method

DOEpatents

Meyer, Thomas N.; Kinosz, Michael J.; Bigler, Nicolas; Arnaud, Guy

2003-04-01

Disclosed is a molten metal injector system including a holder furnace, a casting mold supported above the holder furnace, and a molten metal injector supported from a bottom side of the mold. The holder furnace contains a supply of molten metal having a metal oxide film surface. The bottom side of the mold faces the holder furnace. The mold defines a mold cavity for receiving the molten metal from the holder furnace. The injector projects into the holder furnace and is in fluid communication with the mold cavity. The injector includes a piston positioned within a piston cavity defined by a cylinder for pumping the molten metal upward from the holder furnace and injecting the molten metal into the mold cavity under pressure. The piston and cylinder are at least partially submerged in the molten metal when the holder furnace contains the molten metal. The cylinder further includes a molten metal intake for receiving the molten metal into the piston cavity. The molten metal intake is located below the metal oxide film surface of the molten metal when the holder furnace contains the molten metal. A method of injecting molten metal into a mold cavity of a casting mold is also disclosed.

A Near-Term, High-Confidence Heavy Lift Launch Vehicle

NASA Technical Reports Server (NTRS)

Rothschild, William J.; Talay, Theodore A.

2009-01-01

The use of well understood, legacy elements of the Space Shuttle system could yield a near-term, high-confidence Heavy Lift Launch Vehicle that offers significant performance, reliability, schedule, risk, cost, and work force transition benefits. A side-mount Shuttle-Derived Vehicle (SDV) concept has been defined that has major improvements over previous Shuttle-C concepts. This SDV is shown to carry crew plus large logistics payloads to the ISS, support an operationally efficient and cost effective program of lunar exploration, and offer the potential to support commercial launch operations. This paper provides the latest data and estimates on the configurations, performance, concept of operations, reliability and safety, development schedule, risks, costs, and work force transition opportunities for this optimized side-mount SDV concept. The results presented in this paper have been based on established models and fully validated analysis tools used by the Space Shuttle Program, and are consistent with similar analysis tools commonly used throughout the aerospace industry. While these results serve as a factual basis for comparisons with other launch system architectures, no such comparisons are presented in this paper. The authors welcome comparisons between this optimized SDV and other Heavy Lift Launch Vehicle concepts.

16 CFR 1509.3 - Crib-side height.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Crib-side height. 1509.3 Section 1509.3... REQUIREMENTS FOR NON-FULL-SIZE BABY CRIBS § 1509.3 Crib-side height. (a) With the mattress support in its highest adjustable position and the crib side in its lowest adjustable position, the vertical distance...

16 CFR 1509.3 - Crib-side height.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Crib-side height. 1509.3 Section 1509.3... REQUIREMENTS FOR NON-FULL-SIZE BABY CRIBS § 1509.3 Crib-side height. (a) With the mattress support in its highest adjustable position and the crib side in its lowest adjustable position, the vertical distance...

Apparatus and method for measuring the thickness of a semiconductor wafer

DOEpatents

Ciszek, Theodoer F.

1995-01-01

Apparatus for measuring thicknesses of semiconductor wafers, comprising: housing means for supporting a wafer in a light-tight environment; a light source mounted to the housing at one side of the wafer to emit light of a predetermined wavelength to normally impinge the wafer; a light detector supported at a predetermined distance from a side of the wafer opposite the side on which a light source impinges and adapted to receive light transmitted through the wafer; and means for measuring the transmitted light.

System overview on electromagnetic compensation for reflector antenna surface distortion

NASA Technical Reports Server (NTRS)

Acosta, R. J.; Zaman, A. J.; Terry, J. D.

1993-01-01

The system requirements and hardware implementation for electromagnetic compensation of antenna performance degradations due to thermal effects was investigated. Future commercial space communication antenna systems will utilize the 20/30 GHz frequency spectrum and support very narrow multiple beams (0.3 deg) over wide angle field of view (15-20 beamwidth). On the ground, portable and inexpensive very small aperture terminals (VSAT) for transmitting and receiving video, facsimile and data will be employed. These types of communication system puts a very stringent requirement on spacecraft antenna beam pointing stability (less than .01 deg), high gain (greater than 50 dB) and very lowside lobes (less than -25 dB). Thermal analysis performed on the advanced communication technology satellite (ACTS) has shown that the reflector surfaces, the mechanical supporting structures and metallic surfaces on the spacecraft body will distort due thermal effects from a varying solar flux. The antenna performance characteristics (e.g., pointing stability, gain, side lobe, etc.) will degrade due to thermal distortion in the reflector surface and supporting structures. Specifically, antenna RF radiation analysis has shown that pointing error is the most sensitive antenna performance parameter to thermal distortions. Other antenna parameters like peak gain, cross polarization level (beam isolation), and side lobe level will also degrade with thermal distortions. In order to restore pointing stability and in general antenna performance several compensation methods were proposed. In general these compensation methods can be classified as being either of mechanical or electromagnetic type. This paper will address only the later one. In this approach an adaptive phased array antenna feed is used to compensate for the antenna performance degradation. Extensive work has been devoted to demonstrate the feasibility of adaptive feed compensation on space communication antenna systems. This paper addresses the system requirements for such a system and identify candidate technologies (analog and digital) for possible hardware implementation.

Phenology of the McMurdo Sound Spring Bloom

NASA Astrophysics Data System (ADS)

Daly, K. L.; Kim, S.; Broadbent, H.; Saenz, B.; Ainley, D. G.; Ballard, G.; Pitman, R.; DiTullio, G. R.

2016-02-01

The phenology of spring blooms in most cases has important consequences for the food web that supports upper trophic level predators. An investigation during spring/summer of 2012/13 and 2014/15 of the McMurdo Sound ecosystem, at the southern end of the Ross Sea, revealed that maximum concentrations of fast ice algae occurred during November, with higher concentrations on the eastern side of the Sound near Ross Island and lower concentrations on the western side in the cold water outflow from under the Ross Ice Shelf. In early to mid-December, warming surface water ablated the undersurface of the fast ice and ice algae likely sank rapidly out of the water column to provide food for the benthos. Also in early to mid-December, the McMurdo system transitioned to a phytoplankton bloom at the fast ice edge and under the ice, which co-occurred with the timing of Adelie penguin reproduction (chick hatching) at Cape Royds and the arrival of minke whales and fish-eating killer whales at the fast ice edge. The phytoplankton bloom was initially advected from the Ross Sea into the eastern side of McMurdo Sound and then spread across the Sound to the western side. The phytoplankton community, which was dominated by diatoms and Phaeocystis, was not grazed down by zooplankton and appeared to sink out of the water column. Results support recent findings that a wasp-waist food web structure exists in the Ross Sea, whereby upper trophic levels are not closely coupled to phytoplankton dynamics.

Nozzle airfoil having movable nozzle ribs

DOEpatents

Yu, Yufeng Phillip; Itzel, Gary Michael

2002-01-01

A nozzle vane or airfoil structure is provided in which the nozzle ribs are connected to the side walls of the vane or airfoil in such a way that the ribs provide the requisite mechanical support between the concave side and convex side of the airfoil but are not locked in the radial direction of the assembly, longitudinally of the airfoil. The ribs may be bi-cast onto a preformed airfoil side wall structure or fastened to the airfoil by an interlocking slide connection and/or welding. By attaching the nozzle ribs to the nozzle airfoil metal in such a way that allows play longitudinally of the airfoil, the temperature difference induced radial thermal stresses at the nozzle airfoil/rib joint area are reduced while maintaining proper mechanical support of the nozzle side walls.

Bacteriological evaluation for one-and two-piece implant design supporting mandibular overdenture

PubMed Central

Abdelwahed, Ahmed; Mahrous, Ahmed I.; Abadallah, Mohamed Farouk; Asfour, Hani; Aldawash, Hussien A.; Alagha, Ebaa I.

2015-01-01

Background: This study evaluated and compared the bacteriological effect of two-piece implants and one-piece implants in complete overdenture cases on supporting structures. Materials and Methods: Ten male completely edentulous patients were selected and randomly divided into two equal groups according to the implant design and surgical technique for this study; Group 1: Patients were rehabilitated with complete mandibular overdenture supported by two-piece implants one on each side of the lower arch following two-stage surgical technique and Group 2: Patients were rehabilitated with complete mandibular overdenture supported by one-piece implants one on each side. Evaluation was made at the time of insertion, 6, 12, and 18 months after overdenture insertion, by measuring bacteriological changes around implants abutments. Results: Complete overdenture supported by one-piece implants showed better effect on the bacteriological changes as compared to that supported by two-piece implants. Conclusion: Complete overdenture supported by one-piece implants one on each side of the lower arch showed better effect on the bacteriological changes than using the same prosthesis supported by two-piece implants. PMID:26903697

Prototype Vent Gas Heat Exchanger for Exploration EVA - Performance and Manufacturing Characteristics

NASA Technical Reports Server (NTRS)

Quinn, Gregory J.; Strange, Jeremy; Jennings, Mallory

2013-01-01

NASA is developing new portable life support system (PLSS) technologies, which it is demonstrating in an unmanned ground based prototype unit called PLSS 2.0. One set of technologies within the PLSS provides suitable ventilation to an astronaut while on an EVA. A new component within the ventilation gas loop is a liquid-to-gas heat exchanger to transfer excess heat from the gas to the thermal control system s liquid coolant loop. A unique bench top prototype heat exchanger was built and tested for use in PLSS 2.0. The heat exchanger was designed as a counter-flow, compact plate fin type using stainless steel. Its design was based on previous compact heat exchangers manufactured by United Technologies Aerospace Systems (UTAS), but was half the size of any previous heat exchanger model and one third the size of previous liquid-to-gas heat exchangers. The prototype heat exchanger was less than 40 cubic inches and weighed 2.57 lb. Performance of the heat exchanger met the requirements and the model predictions. The water side and gas side pressure drops were less 0.8 psid and 0.5 inches of water, respectively, and an effectiveness of 94% was measured at the nominal air side pressure of 4.1 psia.

Research on Battery Energy Storage System Based on User Side

NASA Astrophysics Data System (ADS)

Wang, Qian; Zhang, Yichi; Yun, Zejian; Wang, Xuguang; Zhang, Dong; Bian, Di

2018-01-01

This paper introduces the effect of user side energy storage on the user side and the network side, a battery energy storage system for the user side is designed. The main circuit topology of the battery energy storage system based on the user side is given, the structure is mainly composed of two parts: DC-DC two-way half bridge converter and DC-AC two-way converter, a control strategy combining battery charging and discharging characteristics is proposed to decouple the grid side and the energy storage side, and the block diagram of the charging and discharging control of the energy storage system is given. The simulation results show that the battery energy storage system of the user side can not only realize reactive power compensation of low-voltage distribution network, but also improve the power quality of the users.

Supply-side options for an endgame for the tobacco industry.

PubMed

Callard, Cynthia D; Collishaw, Neil E

2013-05-01

Although governments have imposed controls on tobacco company behaviour, they have not yet aligned tobacco industry goals to public health objectives. As a result, tobacco companies have delayed or diminished the impact of imposed public health measures and have not contributed to curbing the epidemic of tobacco use. Over the past decade, several regulatory innovations have been proposed as ways to better align industry actions with public health needs, but none have been put in place. These policy suggestions share the goal of providing a supply-side complement to conventional demand reduction strategies, but they differ in the assumptions they make and in the regulatory and governance approaches they take. Similarly, differing views on ideology and political context within the tobacco control community and between governments may hinder the establishment of a global consensus on the ideal supply-side intervention. A government willing to implement innovative supply-side strategies as part of a tobacco control endgame may not require such consensus if factors specific to their national public health systems or political contexts are supportive.

Supply-side options for an endgame for the tobacco industry

PubMed Central

Callard, Cynthia D; Collishaw, Neil E

2013-01-01

Although governments have imposed controls on tobacco company behaviour, they have not yet aligned tobacco industry goals to public health objectives. As a result, tobacco companies have delayed or diminished the impact of imposed public health measures and have not contributed to curbing the epidemic of tobacco use. Over the past decade, several regulatory innovations have been proposed as ways to better align industry actions with public health needs, but none have been put in place. These policy suggestions share the goal of providing a supply-side complement to conventional demand reduction strategies, but they differ in the assumptions they make and in the regulatory and governance approaches they take. Similarly, differing views on ideology and political context within the tobacco control community and between governments may hinder the establishment of a global consensus on the ideal supply-side intervention. A government willing to implement innovative supply-side strategies as part of a tobacco control endgame may not require such consensus if factors specific to their national public health systems or political contexts are supportive. PMID:23591497

High-speed phosphor-LED wireless communication system utilizing no blue filter

NASA Astrophysics Data System (ADS)

Yeh, C. H.; Chow, C. W.; Chen, H. Y.; Chen, J.; Liu, Y. L.; Wu, Y. F.

2014-09-01

In this paper, we propose and investigate an adaptively 84.44 to 190 Mb/s phosphor-LED visible light communication (VLC) system at a practical transmission distance. Here, we utilize the orthogonal-frequency-division-multiplexing quadrature-amplitude-modulation (OFDM-QAM) modulation with power/bit-loading algorithm in proposed VLC system. In the experiment, the optimal analogy pre-equalization design is also performed at LED-Tx side and no blue filter is used at the Rx side for extending the modulation bandwidth from 1 MHz to 30 MHz. In addition, the corresponding free space transmission lengths are between 75 cm and 2 m under various data rates of proposed VLC. And the measured bit error rates (BERs) of < 3.8×10-3 [forward error correction (FEC) limit] at different transmission lengths and measured data rates can be also obtained. Finally, we believe that our proposed scheme could be another alternative VLC implementation in practical distance, supporting < 100 Mb/s, using commercially available LED and PD (without optical blue filtering) and compact size.

The ESA contribution to the European Satellite Navigation Programme

NASA Astrophysics Data System (ADS)

Lucas, R.; Lo Galbo, P.; de Mateo, M. L.; Steciw, A.; Ashford, E.

1996-02-01

This paper describes the ESA ARTES-9 programme on Global Navigation Satellite Systems (GNSS). This programme will be the ESA contribution to the wider European Satellite Navigation Programme which is to be implemented as a joint effort of the European Union, Eurocontrol and ESA with the support of other European bodies such as telecommunication operators, national civil aviation authorities, national space agencies, industry, universities and R&D institutes in general. In fact, in view of the geographical area concerned, the large number of parties interested, the experience required and the global nature of GNSS, the proposed initiative can only be successful if based on a strong cooperation at a European and international scale. The ESA ARTES-9 programme will consist on one side, of the design, development and validation of the European complement to the GPS and GLONASS systems (GNSS1), and on the other side of the study, design and pre-development of the European contribution to follow-on systems: GNSS2.

When "good" is not always right: effect of the consequences of motor action on valence-space associations.

PubMed

Brouillet, Denis; Milhau, Audrey; Brouillet, Thibaut

2015-01-01

Since the work of Casasanto (2009), it is now well established that valence and laterality are associated. Participants tend to prefer objects presented on their dominant side over items presented on their non-dominant side, and to place good items on their dominant side and bad items on the other side. Several studies highlight that those associations of valence and laterality are accounted for by the greater motor fluency of the dominant hand and various studies noted that these associations could be reversed depending on the way people interact with their environment. Consistently with the Theory of Event Coding, the aim of this work is to show that the consequences of motor actions could also reverse the associations between valence and laterality. Thus, if participants had to place two animals (one good, one bad) on two supports, one stable (no risk of falling), one unstable (risk of falling), we hypothesized that the good item would be placed on the stable support, regardless of the side where it would be put (i.e., on the dominant or non-dominant side). We expected the opposite for the bad item. The results of two experiments are consistent with this prediction and support the claim that the consequences of motor action bias the hedonic connotation of our dominant side.

When “good” is not always right: effect of the consequences of motor action on valence-space associations

PubMed Central

Brouillet, Denis; Milhau, Audrey; Brouillet, Thibaut

2015-01-01

Since the work of Casasanto (2009), it is now well established that valence and laterality are associated. Participants tend to prefer objects presented on their dominant side over items presented on their non-dominant side, and to place good items on their dominant side and bad items on the other side. Several studies highlight that those associations of valence and laterality are accounted for by the greater motor fluency of the dominant hand and various studies noted that these associations could be reversed depending on the way people interact with their environment. Consistently with the Theory of Event Coding, the aim of this work is to show that the consequences of motor actions could also reverse the associations between valence and laterality. Thus, if participants had to place two animals (one good, one bad) on two supports, one stable (no risk of falling), one unstable (risk of falling), we hypothesized that the good item would be placed on the stable support, regardless of the side where it would be put (i.e., on the dominant or non-dominant side). We expected the opposite for the bad item. The results of two experiments are consistent with this prediction and support the claim that the consequences of motor action bias the hedonic connotation of our dominant side. PMID:25798122

14 CFR 23.363 - Side load on engine mount.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Side load on engine mount. 23.363 Section....363 Side load on engine mount. (a) Each engine mount and its supporting structure must be designed for a limit load factor in a lateral direction, for the side load on the engine mount, of not less than...

14 CFR 23.363 - Side load on engine mount.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Side load on engine mount. 23.363 Section....363 Side load on engine mount. (a) Each engine mount and its supporting structure must be designed for a limit load factor in a lateral direction, for the side load on the engine mount, of not less than...

14 CFR 23.363 - Side load on engine mount.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Side load on engine mount. 23.363 Section....363 Side load on engine mount. (a) Each engine mount and its supporting structure must be designed for a limit load factor in a lateral direction, for the side load on the engine mount, of not less than...

14 CFR 23.363 - Side load on engine mount.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Side load on engine mount. 23.363 Section....363 Side load on engine mount. (a) Each engine mount and its supporting structure must be designed for a limit load factor in a lateral direction, for the side load on the engine mount, of not less than...

14 CFR 23.363 - Side load on engine mount.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Side load on engine mount. 23.363 Section....363 Side load on engine mount. (a) Each engine mount and its supporting structure must be designed for a limit load factor in a lateral direction, for the side load on the engine mount, of not less than...

Tachykinin NK-1 and NK-3 selective agonists induce analgesia in the formalin test for tonic pain following intra-VTA or intra-accumbens microinfusions.

PubMed

Altier, N; Stewart, J

1997-12-01

Experiments were designed to examine the analgesic effects induced by selective tachykinin receptor agonists microinfused into either the ventral tegmental area (VTA) or nucleus accumbens septi (NAS). Rats were tested in the formalin test for tonic pain following an injection of 0.05 ml of 2.5% formalin into one hind paw immediately after bilateral intra-VTA infusions of either the NK-1 agonist, GR-73632 (0.005, 0.05 or 0.5 nmol/side), the NK-3 agonist, senktide (0.005, 0.5 or 1.5 nmol/side), or saline. Two weeks later, the saline-treated rats were assessed in the tail-flick test for phasic pain after infusions of the tachykinin agonists. Tail-flick latencies were recorded following immersion of the tail in 55 degrees C hot water at 10 min intervals for 1 h immediately after intra-VTA infusions of either GR-73632 (0.5 nmol/side), senktide (1.5 nmol/side) or saline. In a second group of rats, the same effects were studied after infusions into the nucleus accumbens (NAS) of GR-73632 (0.005, 0.5 or 1.5 nmol/side), senktide (0.005, 0.5 or 1.5 nmol/side), or saline. In both the VTA and NAS, the NK-1 and the NK-3 agonists caused significant analgesia in the formalin test, although the NK-1 agonist appeared to be more effective. Naltrexone (2.0 mg/kg) pretreatment failed to reverse the analgesic effects in the formalin test induced by intra-VTA infusions of the substance P (SP) analog, DiMe-C7 (3.0 microg/side), GR-73632 (0.5 nmol/side), or senktide (1.5 nmol/side). Neither compound given at either site was effective in the tail-flick test. These findings suggest that SP-dopamine (DA) interactions within the mesolimbic DA system play an important role in the inhibition of tonic pain. Furthermore, they support our earlier ideas that activation of midbrain DA systems by SP might play a role in stress- and/or pain-induced analgesia.

Apollo 8 Commander Frank Borman Receives Presidential Call

NASA Technical Reports Server (NTRS)

1968-01-01

Apollo 8 Astronaut Frank Borman, commander of the first manned Saturn V space flight into Lunar orbit, accepted a phone call from the U.S. President Lyndon B. Johnson prior to launch. Borman, along with astronauts William Anders, Lunar Module (LM) pilot, and James Lovell, Command Module (CM) pilot, launched aboard the Apollo 8 mission on December 21, 1968 and returned safely to Earth on December 27, 1968. The mission achieved operational experience and tested the Apollo command module systems, including communications, tracking, and life-support, in cis-lunar space and lunar orbit, and allowed evaluation of crew performance on a lunar orbiting mission. The crew photographed the lunar surface, both far side and near side, obtaining information on topography and landmarks as well as other scientific information necessary for future Apollo landings. All systems operated within allowable parameters and all objectives of the mission were achieved.

Apollo 8 Astronaut Anders Suits Up For Countdown Demonstration Test

NASA Technical Reports Server (NTRS)

1968-01-01

Apollo 8 astronaut William Anders, Lunar Module (LM) pilot, is suited up for the Apollo 8 mission countdown demonstration test. The first manned Apollo mission launched aboard the Saturn V and first manned Apollo craft to enter lunar orbit, the SA-503, Apollo 8 mission lift off occurred on December 21, 1968 and returned safely to Earth on December 27, 1968. Aboard were Anders and fellow astronauts James Lovell, Command Module (CM) pilot; and Frank Borman, commander. The mission achieved operational experience and tested the Apollo command module systems, including communications, tracking, and life-support, in cis-lunar space and lunar orbit, and allowed evaluation of crew performance on a lunar orbiting mission. The crew photographed the lunar surface, both far side and near side, obtaining information on topography and landmarks as well as other scientific information necessary for future Apollo landings. All systems operated within allowable parameters and all objectives of the mission were achieved.

Apollo 8 Astronaut James Lovell On Phone With President Johnson

NASA Technical Reports Server (NTRS)

1968-01-01

Apollo 8 Astronaut James Lovell, Command Module (CM) pilot of the first manned Saturn V space flight into Lunar orbit, accepted a phone call from the U.S. President Lyndon B. Johnson prior to launch. Lovell, along with astronauts William Anders, Lunar Module (LM) pilot, and Frank Borman, commander, launched aboard the Apollo 8 mission on December 21, 1968 and returned safely to Earth on December 27, 1968. The mission achieved operational experience and tested the Apollo command module systems, including communications, tracking, and life-support, in cis-lunar space and lunar orbit, and allowed evaluation of crew performance on a lunar orbiting mission. The crew photographed the lunar surface, both far side and near side, obtaining information on topography and landmarks as well as other scientific information necessary for future Apollo landings. All systems operated within allowable parameters and all objectives of the mission were achieved.

Apollo 8 Astronaut William Anders On Phone With President Johnson

NASA Technical Reports Server (NTRS)

1968-01-01

Apollo 8 Astronaut William Anders, Lunar Module (LM) pilot of the first manned Saturn V space flight into Lunar orbit, accepted a phone call from the U.S. President Lyndon B. Johnson prior to launch. Anders, along with astronauts James Lovell, Command Module (CM) pilot, and Frank Borman, commander, launched aboard the Apollo 8 mission on December 21, 1968 and returned safely to Earth on December 27, 1968. The mission achieved operational experience and tested the Apollo command module systems, including communications, tracking, and life-support, in cis-lunar space and lunar orbit, and allowed evaluation of crew performance on a lunar orbiting mission. The crew photographed the lunar surface, both far side and near side, obtaining information on topography and landmarks as well as other scientific information necessary for future Apollo landings. All systems operated within allowable parameters and all objectives of the mission were achieved.

Pressure-composition relations for coexisting gases and liquids and the critical points in the system NaCl-H2O at 450, 475, and 500°C

USGS Publications Warehouse

Rosenbauer, Robert J.; Bischoff, James L.

1987-01-01

Pressure-temperature-composition (P, T, x) relations for the co-existing vapor and liquid phases in the system NaCl-H2O were determined experimentally at 450, 475, and 500°C. Data for each isotherm includeP-x relations near the critical point and extend to the three-phase assemblage vapor-liquid-halite on the vapor side. On the liquid side the P-x data range from the critical point to the room-temperature halite saturation point (~25 wt.% NaCl). Critical pressures were calculated from measured pressures and compositions and classical theory. The results generally support the few data points of Urusova (1974, 1975) and Ölander and Liander (1950) but differ markedly from the extensive data of Sourirajan andKennedy (1962).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wexler, Jason; Botkin, Jonathan; Culligan, Matthew

A mounting support for a photovoltaic module is described. The mounting support includes a pedestal having a surface adaptable to receive a flat side of a photovoltaic module laminate. A hole is disposed in the pedestal, the hole adaptable to receive a bolt or a pin used to couple the pedestal to the flat side of the photovoltaic module laminate.

Evaluation of Side Stream Filtration Technology at Oak Ridge National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyd, Brian K.

2014-08-01

This technology evaluation was performed by Pacific Northwest National Laboratory and Oak Ridge National Laboratory on behalf of the Federal Energy Management Program. The objective was to quantify the benefits side stream filtration provides to a cooling tower system. The evaluation assessed the performance of an existing side stream filtration system at a cooling tower system at Oak Ridge National Laboratory’s Spallation Neutron Source research facility. This location was selected because it offered the opportunity for a side-by-side comparison of a system featuring side stream filtration and an unfiltered system.

An online model composition tool for system biology models

PubMed Central

2013-01-01

Background There are multiple representation formats for Systems Biology computational models, and the Systems Biology Markup Language (SBML) is one of the most widely used. SBML is used to capture, store, and distribute computational models by Systems Biology data sources (e.g., the BioModels Database) and researchers. Therefore, there is a need for all-in-one web-based solutions that support advance SBML functionalities such as uploading, editing, composing, visualizing, simulating, querying, and browsing computational models. Results We present the design and implementation of the Model Composition Tool (Interface) within the PathCase-SB (PathCase Systems Biology) web portal. The tool helps users compose systems biology models to facilitate the complex process of merging systems biology models. We also present three tools that support the model composition tool, namely, (1) Model Simulation Interface that generates a visual plot of the simulation according to user’s input, (2) iModel Tool as a platform for users to upload their own models to compose, and (3) SimCom Tool that provides a side by side comparison of models being composed in the same pathway. Finally, we provide a web site that hosts BioModels Database models and a separate web site that hosts SBML Test Suite models. Conclusions Model composition tool (and the other three tools) can be used with little or no knowledge of the SBML document structure. For this reason, students or anyone who wants to learn about systems biology will benefit from the described functionalities. SBML Test Suite models will be a nice starting point for beginners. And, for more advanced purposes, users will able to access and employ models of the BioModels Database as well. PMID:24006914

The biomechanics of one-footed vertical jump performance in unilateral trans-tibial amputees.

PubMed

Strike, S C; Diss, C

2005-04-01

This study investigated vertical jumps from single support for two trans-tibial amputees from a standing position. The mechanisms used to achieve flight and the compensatory mechanisms used in the production of force in the absence of plantarflexors are detailed. Two participants completed countermovement maximum vertical jumps from the prosthetic and the sound limbs. The jumps were recorded by a 7-camera 512 VICON motion analysis system integrated with a Kistler forceplate. Flight height was 5 cm jumping from the prosthetic side and 18-19 cm from the sound side. The countermovement was shallower and its duration was less on the prosthetic side compared to the sound side. The reduced and passive range of motion at the prosthesis resulted in an asymmetrical countermovement for both participants with the knee and ankle joints most affected. The duration of the push-off phase was not consistently affected. At take-off the joints on the sound side reached close to full extension while on the prosthetic side they remained more flexed. Joint extension velocity in the push-off phase was similar for both participants on the sound side, though the timing for participant 2 illustrated earlier peaks. The pattern of joint extension velocity was not a smooth proximal to distal sequence on the prosthetic side. The magnitude and timing of the inter-segment extensor moments were asymmetrical for both subjects. The power pattern was asymmetrical in both the countermovement and push-off phases; the lack of power generation at the ankle affected that produced at the remaining joints.

The standardized functional support sectional for the Small Astronomy Satellite (SAS)

NASA Technical Reports Server (NTRS)

Townsend, M. R.

1974-01-01

The standardized functional support section for the improved Small Astronomy Satellite (SAS) spacecraft, which can be used virtually without change for a wide variety of experimental packages and missions, is described. This functional support section makes the spacecraft remarkably flexible for a small satellite. Able to point its thrust axis to any direction in space, it can also spin or slow its outer body rotation to zero for star- or earth-locked pointing of side-viewing experiments. It features a reprogrammable telemetry system, a delayed command system, and an improved control system. Experiments can be built independently and attached to the SAS spacecraft just prior to final acceptance testing and launch. The spacecraft subsystems are described in detail. Included are a summary of the spacecraft characteristics, special design considerations, project reliability requirements, and environmental test conditions. It is intended that this new functional support section afford virtual off-the-shelf availability of the SAS spacecraft to independently built experiments, thus providing quick response time and minimum cost in meeting a wide variety of experimenter needs.

Health information systems.

PubMed

Hovenga, Evelyn J S; Grain, Heather

2013-01-01

Health information provides the foundation for all decision making in healthcare whether clinical at the bed side, or at a national government level. This information is generally collected as part of systems which support administrative or clinical workflow and practice. This chapter describes the many and varied features of systems such as electronic health records (EHRs), how they fit with health information systems and how they collectively manage information flow. Systems engineering methods and tools are described together with their use to suit the health industry. This focuses on the need for suitable system architectures and semantic interoperability. These concepts and their relevance to the health industry are explained. The relationship and requirements for appropriate data governance in these systems is also considered.

A remote condition monitoring system for wind-turbine based DG systems

NASA Astrophysics Data System (ADS)

Ma, X.; Wang, G.; Cross, P.; Zhang, X.

2012-05-01

In this paper, a remote condition monitoring system is proposed, which fundamentally consists of real-time monitoring modules on the plant side, a remote support centre and the communications between them. The paper addresses some of the key issues related on the monitoring system, including i) the implementation and configuration of a VPN connection, ii) an effective database system to be able to handle huge amount of monitoring data, and iii) efficient data mining techniques to convert raw data into useful information for plant assessment. The preliminary results have demonstrated that the proposed system is practically feasible and can be deployed to monitor the emerging new energy generation systems.

The sensorimotor and social sides of the architecture of speech.

PubMed

Pezzulo, Giovanni; Barca, Laura; D'Ausilio, Alessando

2014-12-01

Speech is a complex skill to master. In addition to sophisticated phono-articulatory abilities, speech acquisition requires neuronal systems configured for vocal learning, with adaptable sensorimotor maps that couple heard speech sounds with motor programs for speech production; imitation and self-imitation mechanisms that can train the sensorimotor maps to reproduce heard speech sounds; and a "pedagogical" learning environment that supports tutor learning.

Apparatus and method for measuring the thickness of a semiconductor wafer

DOEpatents

Ciszek, T.F.

1995-03-07

Apparatus for measuring thicknesses of semiconductor wafers is discussed, comprising: housing means for supporting a wafer in a light-tight environment; a light source mounted to the housing at one side of the wafer to emit light of a predetermined wavelength to normally impinge the wafer; a light detector supported at a predetermined distance from a side of the wafer opposite the side on which a light source impinges and adapted to receive light transmitted through the wafer; and means for measuring the transmitted light. 4 figs.

Do users desire symmetrical lumbar supports in task seating?

PubMed

Fredericks, Tycho K; Butt, Steven E; Kumar, Anil R; Bellingar, Teresa

2016-07-01

This research was designed to objectively investigate the desired low back (lumbar) support in a task chair; specifically by allowing a user to self-select the magnitude and location of support. An experimental chair built specifically for this study allowed the users to remotely adjust 35 diodes to achieve their desired level of support. Pressure mapping was used to measure the interface pressure at the user-seat back interface. It was determined that 73.8% of the 201 participants in this study, self-selected asymmetrical lower back support that was at least 20% greater on one side vs. the other. Additionally, 16.9% of the participants self-selected support on one side which was at least twice that of the other side. Contrary to popular practice, participants were found to prefer asymmetric support in the lower back region. It is anticipated that the culmination of this research will aid chair manufacturers in designing adaptable back rests. Practitioner Summary: Most current lumbar supports are designed to move vertically and to symmetrically increase or decrease in firmness as per a user's adjustment. This investigation highlights that participants tended to select asymmetrical lumbar support, and as such, designers should consider providing lumbar supports that provide the desired support at appropriate locations.

Collaboration for Land, Air, Sea, and Space Vehicles: Developing the Common Ground in Vehicle Dynamics, System Identification, Control, and Handling Qualities (La collaboration dans le domaine des vehicules terrestres, aeriens, maritimes et spatiaux: L’etablissement d’une approche commune de la dynamique des vehicules, l’identification des systemes, et les qualite’s de controle et de pilotage)

DTIC Science & Technology

2002-11-01

slots in the side of the tail boom, which, by coupling with the predominately downward flow induced by the main rotor , produces “Coanda Effect ” and thus...conduct and promote cooperative research and information exchange. The objective is to support the development and effective use of national defence...decision makers. The RTO performs its mission with the support of an extensive network of national experts. It also ensures effective coordination with

Continuous production of polymethylpentene membranes

DOEpatents

Epperson, B.J.; Burnett, L.J.; Helm, V.D.

1983-11-15

Gas separation membranes may be prepared in a continuous manner by passing a porous support which may, if so desired, be backed by a fabric through a solution of polymethylpentene dissolved in an organic solvent such as hexane. The support member is passed through the solution while one side thereof is in contact with a roller, thereby permitting only one side of the support member to be coated with the polymer. After continuously withdrawing the support member from the bath, the solvent is allowed to evaporate and the resulting membrane is recovered.

AC/DC Power Systems with Applications for future Lunar/Mars base and Crew Exploration Vehicle

NASA Technical Reports Server (NTRS)

Chowdhury, Badrul H.

2005-01-01

ABSTRACT The Power Systems branch at JSC faces a number of complex issues as it readies itself for the President's initiative on future space exploration beyond low earth orbit. Some of these preliminary issues - those dealing with electric power generation and distribution on board Mars-bound vehicle and that on Lunar and Martian surface may be summarized as follows: Type of prime mover - Because solar power may not be readily available on parts of the Lunar/Mars surface and also during the long duration flight to Mars, the primary source of power will most likely be nuclear power (Uranium fuel rods) with a secondary source of fuel cell (Hydrogen supply). The electric power generation source - With nuclear power being the main prime mover, the electric power generation source will most likely be an ac generator at a yet to be determined frequency. Thus, a critical issue is whether the generator should generate at constant or variable frequency. This will decide what type of generator to use - whether it is a synchronous machine, an asynchronous induction machine or a switched reluctance machine. The type of power distribution system - the distribution frequency, number of wires (3- wire, 4-wire or higher), and ac/dc hybridization. Building redundancy and fault tolerance in the generation and distribution sub-systems so that the system is safe; provides 100% availability to critical loads; continues to operate even with faulted sub-systems; and requires minimal maintenance. This report descril_es results of a summer faculty fellowship spent in the Power Systems Branch with the specific aim of investigating some of the lessons learned in electric power generation and usage from the terrestrial power systems industry, the aerospace industry as well as NASA's on-going missions so as to recommend novel surface and vehicle-based power systems architectures in support of future space exploration initiatives. A hybrid ac/dc architecture with source side and load side redundancies and including emergency generators on both ac and dc sides is proposed. The generation frequency is 400 Hz mostly because of the technology maturity at this frequency in the aerospace industry. Power will be distributed to several ac load distribution buses through solid state variable speed, constant frequency converters on the ac side. A segmented dc ring bus supplied from ac/dc converters and with the capability of connecting/disconnecting the segments will supply power to multiple de load distribution buses. The system will have the capability of reverse flow from dc to ac side in the case of an extreme emergency on the main ac generation side.

Tube support grid and spacer therefor

DOEpatents

Ringsmuth, Richard J.; Kaufman, Jay S.

1986-01-01

A tube support grid and spacers therefor provide radially inward preloading of heat exchange tubes to minimize stress upon base welds due to differential thermal expansion. The grid comprises a concentric series of rings and spacers with opposing concave sides for conforming to the tubes and V-shaped ends to provide resilient flexibility. The flexibility aids in assembly and in transmitting seismic vibrations from the tubes to a shroud. The tube support grid may be assembled in place to achieve the desired inwardly radial preloading of the heat exchange tubes. Tab and slot assembly further minimizes stresses in the system. The radii of the grid rings may be preselected to effect the desired radially inward preloading.

Java-based browsing, visualization and processing of heterogeneous medical data from remote repositories.

PubMed

Masseroli, M; Bonacina, S; Pinciroli, F

2004-01-01

The actual development of distributed information technologies and Java programming enables employing them also in the medical arena to support the retrieval, integration and evaluation of heterogeneous data and multimodal images in a web browser environment. With this aim, we used them to implement a client-server architecture based on software agents. The client side is a Java applet running in a web browser and providing a friendly medical user interface to browse and visualize different patient and medical test data, integrating them properly. The server side manages secure connections and queries to heterogeneous remote databases and file systems containing patient personal and clinical data. Based on the Java Advanced Imaging API, processing and analysis tools were developed to support the evaluation of remotely retrieved bioimages through the quantification of their features in different regions of interest. The Java platform-independence allows the centralized management of the implemented prototype and its deployment to each site where an intranet or internet connection is available. Giving healthcare providers effective support for comprehensively browsing, visualizing and evaluating medical images and records located in different remote repositories, the developed prototype can represent an important aid in providing more efficient diagnoses and medical treatments.

Solid oxide fuel cell generator with removable modular fuel cell stack configurations

DOEpatents

Gillett, J.E.; Dederer, J.T.; Zafred, P.R.; Collie, J.C.

1998-04-21

A high temperature solid oxide fuel cell generator produces electrical power from oxidation of hydrocarbon fuel gases such as natural gas, or conditioned fuel gases, such as carbon monoxide or hydrogen, with oxidant gases, such as air or oxygen. This electrochemical reaction occurs in a plurality of electrically connected solid oxide fuel cells bundled and arrayed in a unitary modular fuel cell stack disposed in a compartment in the generator container. The use of a unitary modular fuel cell stack in a generator is similar in concept to that of a removable battery. The fuel cell stack is provided in a pre-assembled self-supporting configuration where the fuel cells are mounted to a common structural base having surrounding side walls defining a chamber. Associated generator equipment may also be mounted to the fuel cell stack configuration to be integral therewith, such as a fuel and oxidant supply and distribution systems, fuel reformation systems, fuel cell support systems, combustion, exhaust and spent fuel recirculation systems, and the like. The pre-assembled self-supporting fuel cell stack arrangement allows for easier assembly, installation, maintenance, better structural support and longer life of the fuel cells contained in the fuel cell stack. 8 figs.

Solid oxide fuel cell generator with removable modular fuel cell stack configurations

DOEpatents

Gillett, James E.; Dederer, Jeffrey T.; Zafred, Paolo R.; Collie, Jeffrey C.

1998-01-01

A high temperature solid oxide fuel cell generator produces electrical power from oxidation of hydrocarbon fuel gases such as natural gas, or conditioned fuel gases, such as carbon monoxide or hydrogen, with oxidant gases, such as air or oxygen. This electrochemical reaction occurs in a plurality of electrically connected solid oxide fuel cells bundled and arrayed in a unitary modular fuel cell stack disposed in a compartment in the generator container. The use of a unitary modular fuel cell stack in a generator is similar in concept to that of a removable battery. The fuel cell stack is provided in a pre-assembled self-supporting configuration where the fuel cells are mounted to a common structural base having surrounding side walls defining a chamber. Associated generator equipment may also be mounted to the fuel cell stack configuration to be integral therewith, such as a fuel and oxidant supply and distribution systems, fuel reformation systems, fuel cell support systems, combustion, exhaust and spent fuel recirculation systems, and the like. The pre-assembled self-supporting fuel cell stack arrangement allows for easier assembly, installation, maintenance, better structural support and longer life of the fuel cells contained in the fuel cell stack.

Blood RNA biomarker panel detects both left- and right-sided colorectal neoplasms: a case-control study.

PubMed

Chao, Samuel; Ying, Jay; Liew, Gailina; Marshall, Wayne; Liew, Choong-Chin; Burakoff, Robert

2013-07-23

Colonoscopy is widely regarded to be the gold standard for colorectal cancer (CRC) detection. Recent studies, however, suggest that the effectiveness of colonoscopy is mostly confined to tumors on the left side of the colon (descending, sigmoid, rectum), and that the technology has poor tumor detection for right-sided (cecum, ascending, transverse) lesions. A minimally invasive test that can detect both left-sided and right-sided lesions could increase the effectiveness of screening colonoscopy by revealing the potential presence of neoplasms in the right-sided "blind spot". We previously reported on a seven-gene, blood-based biomarker panel that effectively stratifies a patient's risk of having CRC. For the current study, we assessed the effectiveness of the seven-gene panel for the detection of left- and right-sided CRC lesions. Results were evaluated for 314 patients with CRC (left-sided: TNM I, 65; TNM II, 57; TNM III, 60; TNM IV, 17; unknown, 9. right-sided: TNM I, 28; TNM II, 29; TNM III, 38; TNM IV, 12; unknown, 1 and including two samples with both left and right lesions) and 328 control samples. Blood samples were obtained prior to clinical staging and therapy. Most CRC subjects had localized disease (stages I and II, 58%); regional (stage III) and systemic (stage IV) disease represented 32% and 9%, respectively, of the study population. The panel detected left-sided (74%, 154/208) and right-sided (85%, 92/108) lesions with an overall sensitivity of 78% (215/316) at a specificity of 66% (215/328). Treatable cancer (stages I to III) was detected with left-sided lesion sensitivity of 76% (138/182) and right-sided sensitivity of 84% (80/95). This seven-gene biomarker panel detected right-sided CRC lesions across all cancer stages with a sensitivity that is at least equal to that for left-sided lesions. This study supports the use of this panel as the basis for a patient-friendly, blood-based test that can be easily incorporated into a routine physical examination in advance of colonoscopy to provide a convenient companion diagnostic and a pre-screening alert, ultimately leading to enhanced CRC screening effectiveness.

75 FR 3660 - Airworthiness Directives; The Boeing Company Model 757 Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-22

... airplanes. This proposed AD would require repetitive inspections for corrosion and cracking in the front... side link support fitting at WS 292. We are proposing this AD to detect and correct such corrosion and... fastener locations common to the side link support fitting at WS 292. This area is not covered by the...

The partial root-zone saline irrigation system and antioxidant responses in tomato plants.

PubMed

Alves, Rita de Cássia; de Medeiros, Ana Santana; Nicolau, Mayara Cristina Malvas; Neto, Antônio Pizolato; de Assis Oliveira, Francisco; Lima, Leonardo Warzea; Tezotto, Tiago; Gratão, Priscila Lupino

2018-06-01

Salinity is a limiting factor that can affect plant growth and cause significant losses in agricultural productivity. This study provides an insight about the viability of partial root-zone irrigation (PRI) system with saline water supported by a biochemical approach involving antioxidant responses. Six different irrigation methods using low and high salt concentrations (S1-0.5 and S2-5.0 dS m -1 ) were applied, with or without PRSI, so that one side of the root-zone was submitted to saline water while the other side was low salinity water irrigated. The results revealed different responses according to the treatments and the PRSI system applied. For the treatments T1, T2 and T3, the PRSI was not applied, while T4, T5 and T6 treatments were applied with PRSI system. Lipid peroxidation, proline content, and activities of SOD, CAT, APX, GR and GSH in tomato plants subjected to PRSI system were analyzed. Plant growth was not affected by the salt concentrations; however, plants submitted to high salt concentrations showed high MDA content and Na + accumulation when compared to the control plants. Plants submitted to treatments T4, T5 and T6 with PRSI system exhibited lower MDA compared to the control plants (T1). Proline content and activities of SOD, CAT, APX, GR and GSH content were maintained in all treatments and tissues analyzed, with only exception for APX in fruits and GSH content, in roots. The overall results showed that PRSI system could be an applicable technique for saline water supply on irrigation since plants did not show to be vulnerable to salt stress, supported by a biochemical approach involving antioxidant responses. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Research on large-aperture primary mirror supporting way of vehicle-mounted laser communication system

NASA Astrophysics Data System (ADS)

Meng, Lixin; Meng, Lingchen; Zhang, Yiqun; Zhang, Lizhong; Liu, Ming; Li, Xiaoming

2018-01-01

In the satellite to earth laser communication link, large-aperture ground laser communication terminals usually are used in order to realize the requirement of high rate and long distance communication and restrain the power fluctuation by atmospheric scintillation. With the increasing of the laser communication terminal caliber, the primary mirror weight should also be increased, and selfweight, thermal deformation and environment will affect the surface accuracy of the primary mirror surface. A high precision vehicular laser communication telescope unit with an effective aperture of 600mm was considered in this paper. The primary mirror is positioned with center hole, which back is supported by 9 floats and the side is supported by a mercury band. The secondary mirror adopts a spherical adjusting mechanism. Through simulation analysis, the system wave difference is better than λ/20 when the primary mirror is in different dip angle, which meets the requirements of laser communication.

e-Learning system ERM for medical radiation physics education.

PubMed

Stoeva, Magdalena; Cvetkov, Asen

2005-09-01

The objective of this paper is to present the Education for Radiation in Medicine (ERM) e-Learning System. The system was developed, tested and piloted in the Inter-University Medical Physics Centre, Plovdiv, Bulgaria. It was based on the results of EU Project TEMPUS S-JEP 09826. The ERM e-Learning System is an integrated on-line system for remote education covering aspects of Medical Radiation Physics education (M.Sc. level). It provides user-friendly interface and optimised functionality with three different access levels: trainee, professor and administrator. The minimum server requirements and the standard client side working environment turn the system into a good, cost effective and easy to support solution for remote education.

Pros and cons of healthcare information technology implementation: the pros win.

PubMed

Maffei, Roxana

2006-01-01

Countless studies and investigations have been performed siding either for or against the implementation of technology in the healthcare setting. This article presents both sides of this debate, with an obvious conclusion that the pros of this debate win. The practice of information technology in the medical domain lags behind its knowledge and discovery by at least 7 years. The key to closing this gap is to show, through various studies, how information technology systems provide decision support to users at the point in time when decisions are needed. What the reader will obtain from this article is that the pros for information technology implementation in healthcare settings weigh much more and have a greater effect than the cons.

The effect of real-time pricing on load shifting in a highly renewable power system dominated by generation from the renewable sources of wind and photovoltaics

NASA Astrophysics Data System (ADS)

Kies, Alexander; Brown, Tom; Schlachtberger, David; Schramm, Stefan

2017-04-01

The supply-demand imbalance is a major concern in the presence of large shares of highly variable renewable generation from sources like wind and photovoltaics (PV) in power systems. Other than the measures on the generation side, such as flexible backup generation or energy storage, sector coupling or demand side management are the most likely option to counter imbalances, therefore to ease the integration of renewable generation. Demand side management usually refers to load shifting, which comprises the reaction of electricity consumers to price fluctuations. In this work, we derive a novel methodology to model the interplay of load shifting and provided incentives via real-time pricing in highly renewable power systems. We use weather data to simulate generation from the renewable sources of wind and photovoltaics, as well as historical load data, split into different consumption categories, such as, heating, cooling, domestic, etc., to model a simplified power system. Together with renewable power forecast data, a simple market model and approaches to incorporate sector coupling [1] and load shifting [2,3], we model the interplay of incentives and load shifting for different scenarios (e.g., in dependency of the risk-aversion of consumers or the forecast horizon) and demonstrate the practical benefits of load shifting. First, we introduce the novel methodology and compare it with existing approaches. Secondly, we show results of numerical simulations on the effects of load shifting: It supports the integration of PV power by providing a storage, which characteristics can be described as "daily" and provides a significant amount of balancing potential. Lastly, we propose an experimental setup to obtain empirical data on end-consumer load-shifting behaviour in response to price incentives. References [1] Brown, T., Schlachtberger, D., Kies. A., Greiner, M., Sector coupling in a highly renewable European energy system, Proc. of the 15th International Workshop on Large-Scale Integration of Wind Power into Power Systems as well as on Transmission Networks for Offshore Wind Power Plants, Vienna, Austria, 15.-17. November 2016 [2] Kleinhans, D.: Towards a systematic characterization of the potential of demand side management, arXiv preprint arXiv:1401.4121, 2014 [3] Kies, A., Schyska, B. U., von Bremen, L., The Demand Side Management Potential to Balance a Highly Renewable European Power System. Energies, 9(11), 955, 2016

Ankle antagonist coactivation in the double-support phase of walking: Stroke vs. healthy subjects.

PubMed

Silva, Augusta; Sousa, Andreia S P; Silva, Cláudia; Tavares, João Manuel R S; Santos, Rubim; Sousa, Filipa

2015-01-01

Lesions in ipsilateral systems related to postural control in the ipsilesional side may justify the lower performance of stroke subjects during walking. To analyze bilateral ankle antagonist coactivation during double support in stroke subjects. Sixteen (8 females; 8 males) subjects with a first isquemic stroke and 22 controls (12 females; 10 males) participated in this study. The double-support phase was assessed through ground reaction forces and the electromyography of ankle muscles was assessed in both limbs. The ipsilesional limb presented statistically significant differences from the control when assuming specific roles during double support. The tibialis anterior and soleus pair was the one in which this atypical behavior was more pronounced. The ipsilesional limb presents a dysfunctional behavior when a higher postural control activity was demanded.

Building a Unique Scenario to Support Cross-Mission Science with SPICE: The Siding-Spring comet encounter with Mars

NASA Astrophysics Data System (ADS)

Costa, M.; Witasse, O.; Sánchez-Cano, B.

2017-09-01

On October 2014, Mars experienced a close encounter with Comet Siding Spring. This contribution outlines a SPICE scenario built to assist studies combining MEX, MAVEN, Mars Odyssey, MSL, and Siding-Spring data focused on a Cosmographia 3D scenario.

Motivation and Design of the Sirocco Storage System Version 1.0.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Curry, Matthew Leon; Ward, H. Lee; Danielson, Geoffrey Charles

Sirocco is a massively parallel, high performance storage system for the exascale era. It emphasizes client-to-client coordination, low server-side coupling, and free data movement to improve resilience and performance. Its architecture is inspired by peer-to-peer and victim- cache architectures. By leveraging these ideas, Sirocco natively supports several media types, including RAM, flash, disk, and archival storage, with automatic migration between levels. Sirocco also includes storage interfaces and support that are more advanced than typical block storage. Sirocco enables clients to efficiently use key-value storage or block-based storage with the same interface. It also provides several levels of transactional data updatesmore » within a single storage command, including full ACID-compliant updates. This transaction support extends to updating several objects within a single transaction. Further support is provided for con- currency control, enabling greater performance for workloads while providing safe concurrent modification. By pioneering these and other technologies and techniques in the storage system, Sirocco is poised to fulfill a need for a massively scalable, write-optimized storage system for exascale systems. This is version 1.0 of a document reflecting the current and planned state of Sirocco. Further versions of this document will be accessible at http://www.cs.sandia.gov/Scalable_IO/ sirocco .« less

Inboard seal mounting

DOEpatents

Hayes, John R.

1983-01-01

A regenerator assembly for a gas turbine engine has a hot side seal assembly formed in part by a cast metal engine block having a seal recess formed therein that is configured to supportingly receive ceramic support blocks including an inboard face thereon having a regenerator seal face bonded thereto. A pressurized leaf seal is interposed between the ceramic support block and the cast metal engine block to bias the seal wear face into sealing engagement with a hot side surface of a rotary regenerator matrix.

Metallization of bacterial cellulose for electrical and electronic device manufacture

DOEpatents

Evans, Barbara R.; O'Neill, Hugh M.; Jansen, Valerie Malyvanh; Woodward, Jonathan

2006-01-17

The employment of metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The fuel cell includes an electrolyte membrane comprising a membrane support structure comprising bacterial cellulose, an anode disposed on one side of the electrolyte membrane, and a cathode disposed on an opposite side of the electrolyte membrane. At least one of the anode and the cathode comprises an electrode support structure comprising bacterial cellulose, and a catalyst disposed in or on the electrode support structure.

STS-31 Hubble Space Telescope (HST) solar array (SA) deploy aboard OV-103

NASA Image and Video Library

1990-04-25

During STS-31, the Hubble Space Telescope (HST) is held in appendage deploy position by Discovery's, Orbiter Vehicle (OV) 103's, remote manipulator system (RMS) above the payload bay (PLB) and crew compartment cabin. While in this position the solar array (SA) wing bistem cassette (HST center) is deployed from its stowed location along side the Support System Module (SSM) forward shell. A high gain antenna (HGA) remains stowed along the SSM. The Earth's surface and the Earth limb creates a dramatic backdrop.

Conflict with Mothers-in-Law and Taiwanese Women's Marital Satisfaction: The Moderating Role of Husband Support

ERIC Educational Resources Information Center

Wu, Tsui-Feng; Yeh, Kuang-Hui; Cross, Susan E.; Larson, Lisa M.; Wang, Yi-Chao; Tsai, Yi-Lin

2010-01-01

This study applies social support theory to the question of whether four types of husband behavior (taking the wife's side, problem solving, ignoring conflict, and taking the mother's side) moderate the association between conflict with the mother-in-law and a Taiwanese woman's marital satisfaction. Data were collected from 125 married Taiwanese…

Integrated Care and Connected Health Approaches Leveraging Personalised Health through Big Data Analytics.

PubMed

Maglaveras, Nicos; Kilintzis, Vassilis; Koutkias, Vassilis; Chouvarda, Ioanna

2016-01-01

Integrated care and connected health are two fast evolving concepts that have the potential to leverage personalised health. From the one side, the restructuring of care models and implementation of new systems and integrated care programs providing coaching and advanced intervention possibilities, enable medical decision support and personalized healthcare services. From the other side, the connected health ecosystem builds the means to follow and support citizens via personal health systems in their everyday activities and, thus, give rise to an unprecedented wealth of data. These approaches are leading to the deluge of complex data, as well as in new types of interactions with and among users of the healthcare ecosystem. The main challenges refer to the data layer, the information layer, and the output of information processing and analytics. In all the above mentioned layers, the primary concern is the quality both in data and information, thus, increasing the need for filtering mechanisms. Especially in the data layer, the big biodata management and analytics ecosystem is evolving, telemonitoring is a step forward for data quality leverage, with numerous challenges still left to address, partly due to the large number of micro-nano sensors and technologies available today, as well as the heterogeneity in the users' background and data sources. This leads to new R&D pathways as it concerns biomedical information processing and management, as well as to the design of new intelligent decision support systems (DSS) and interventions for patients. In this paper, we illustrate these issues through exemplar research targeting chronic patients, illustrating the current status and trends in PHS within the integrated care and connected care world.

On the Importance of "Front-Side Mechanics" in Athletics Sprinting.

PubMed

Haugen, Thomas; Danielsen, Jørgen; Alnes, Leif Olav; McGhie, David; Sandbakk, Øyvind; Ettema, Gertjan

2018-05-16

Practitioners have, for many years, argued that athletic sprinters should optimize front-side mechanics (leg motions occurring in front of the extended line through the torso) and minimize back-side mechanics. This study aimed to investigate if variables related to front- and back-side mechanics can be distinguished from other previously highlighted kinematic variables (spatiotemporal variables and variables related to segment configuration and velocities at touchdown) in how they statistically predict performance. A total of 24 competitive sprinters (age: 23.1 [3.4] y, height: 1.81 [0.06] m, body mass: 75.7 [5.6] kg, and 100-m personal best: 10.86 [0.22] s) performed two 20-m starts from block and 2 to 3 flying sprints over 20 m. Kinematics were recorded in 3D using a motion tracking system with 21 cameras at a 250 Hz sampling rate. Several front- and back-side variables, including thigh (r = .64) and knee angle (r = .51) at lift-off and maximal thigh extension (r = .66), were largely correlated (P < .05) with accelerated running performance, and these variables displayed significantly higher correlations (P < .05) to accelerated running performance than nearly all the other analyzed variables. However, the relationship directions for most front- and back-side variables during accelerated running were opposite in comparison to how the theoretical concept has been described. Horizontal ankle velocity, contact time, and step rate displayed significantly higher correlation values to maximal velocity sprinting than the other variables (P < .05), and neither of the included front- and back-side variables were significantly associated with maximal velocity sprinting. Overall, the present findings did not support that front-side mechanics were crucial for sprint performance among the investigated sprinters.

Machine learning-based prediction of adverse drug effects: An example of seizure-inducing compounds.

PubMed

Gao, Mengxuan; Igata, Hideyoshi; Takeuchi, Aoi; Sato, Kaoru; Ikegaya, Yuji

2017-02-01

Various biological factors have been implicated in convulsive seizures, involving side effects of drugs. For the preclinical safety assessment of drug development, it is difficult to predict seizure-inducing side effects. Here, we introduced a machine learning-based in vitro system designed to detect seizure-inducing side effects. We recorded local field potentials from the CA1 alveus in acute mouse neocortico-hippocampal slices, while 14 drugs were bath-perfused at 5 different concentrations each. For each experimental condition, we collected seizure-like neuronal activity and merged their waveforms as one graphic image, which was further converted into a feature vector using Caffe, an open framework for deep learning. In the space of the first two principal components, the support vector machine completely separated the vectors (i.e., doses of individual drugs) that induced seizure-like events and identified diphenhydramine, enoxacin, strychnine and theophylline as "seizure-inducing" drugs, which indeed were reported to induce seizures in clinical situations. Thus, this artificial intelligence-based classification may provide a new platform to detect the seizure-inducing side effects of preclinical drugs. Copyright © 2017 The Authors. Production and hosting by Elsevier B.V. All rights reserved.

The Portuguese generic medicines market: a policy analysis

PubMed Central

Simoens, Steven

2008-01-01

Objectives: This study aims to conduct a descriptive analysis of the policy environment surrounding the generic medicines retail market in Portugal. The policy analysis focuses on supply-side measures (i.e. market access, pricing, reference-pricing and reimbursement of generic medicines) and demand-side measures (i.e. incentives for physicians to prescribe, for pharmacists to dispense and for patients to use generic medicines). Methods: The policy analysis was based on an international literature review. Also, a simulation exercise was carried out to compute potential savings from substituting generic for originator medicines in Portugal using IMS Health data. Results: Portugal has developed a successful generic medicines market by increasing reimbursement of generic medicines (until October 2005), by introducing a reference-pricing system, by encouraging physicians to prescribe by international non-proprietary name (INN), and by allowing generic substitution by pharmacists. However, the development of the generic medicines market has been hindered by the existence of copies, pricing regulation, certain features of the reference-pricing system, weak incentives for physicians to prescribe generic medicines and a financial disincentive for pharmacists to dispense generic medicines. Increased generic substitution would be expected to reduce public expenditure on originator medicines by 45%. Conclusions: The development of the Portuguese generic medicines market has mainly been fuelled by supply-side measures. To support the further expansion of the market, policy makers need to strengthen demand-side measures inciting physicians to prescribe, pharmacists to dispense and patients to use generic medicines. PMID:25152781

A compliant, banded outflow cannula for decreased afterload sensitivity of rotary right ventricular assist devices.

PubMed

Gregory, Shaun D; Schummy, Emma; Pearcy, Mark; Pauls, Jo P; Tansley, Geoff; Fraser, John F; Timms, Daniel

2015-02-01

Biventricular support with dual rotary ventricular assist devices (VADs) has been implemented clinically with restriction of the right VAD (RVAD) outflow cannula to artificially increase afterload and, therefore, operate within recommended design speed ranges. However, the low preload and high afterload sensitivity of these devices increase the susceptibility of suction events. Active control systems are prone to sensor drift or inaccurate inferred (sensor-less) data, therefore an alternative solution may be of benefit. This study presents the in vitro evaluation of a compliant outflow cannula designed to passively decrease the afterload sensitivity of rotary RVADs and minimize left-sided suction events. A one-way fluid-structure interaction model was initially used to produce a design with suitable flow dynamics and radial deformation. The resultant geometry was cast with different initial cross-sectional restrictions and concentrations of a softening diluent before evaluation in a mock circulation loop. Pulmonary vascular resistance (PVR) was increased from 50 dyne s/cm(5) until left-sided suction events occurred with each compliant cannula and a rigid, 4.5 mm diameter outflow cannula for comparison. Early suction events (PVR ∼ 300 dyne s/cm(5) ) were observed with the rigid outflow cannula. Addition of the compliant section with an initial 3 mm diameter restriction and 10% diluent expanded the outflow restriction as PVR increased, thus increasing RVAD flow rate and preventing left-sided suction events at PVR levels beyond 1000 dyne s/cm(5) . Therefore, the compliant, restricted outflow cannula provided a passive control system to assist in the prevention of suction events with rotary biventricular support while maintaining pump speeds within normal ranges of operation. Copyright © 2014 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

A Solution to the Mysteries of Morality

ERIC Educational Resources Information Center

DeScioli, Peter; Kurzban, Robert

2013-01-01

We propose that moral condemnation functions to guide bystanders to choose the same side as other bystanders in disputes. Humans interact in dense social networks, and this poses a problem for bystanders when conflicts arise: which side, if any, to support. Choosing sides is a difficult strategic problem because the outcome of a conflict…

Teaching Spatial Awareness In Small-Sided Games

ERIC Educational Resources Information Center

Phillips, David; Hannon, James C.; Molina, Sergio

2015-01-01

This article supports the use of strategy and tactics at games stage three (how to teach basic offensive and defensive strategy using small-sided games) as a best practices in physical education. Potential learning through game stages three and four (full-sided games) is only possible when teachers have advanced content knowledge to teach the…

What Teacher Collaboration Looks Like

ERIC Educational Resources Information Center

Vincente, Joseph

2017-01-01

In this article, Joseph Vincente, an assistant principal and math and instructional coach at East Side Community High School in New York City, describes East Side's collaborative structures as well as the norms and conditions that support them. Collaboration underpins how the teachers at East Side structure and conduct most of their work, how they…

STS-52 deployment of LAGEOS / IRIS spacecraft from OV-102's payload bay (PLB)

NASA Technical Reports Server (NTRS)

1992-01-01

During STS-52 deployment activities, the Italian Research Interim Stage (IRIS), a spinning solid fuel rocket, lifts the Laser Geodynamic Satellite II (LAGEOS II) out of its support cradle and above the thermal shield aboard Columbia, Orbiter Vehicle (OV) 102. The remote manipulator system (RMS) arm, with Material Exposure in Low Earth Orbit (MELEO), is positioned above the port side sill longeron. On the mission-peculiar equipment support structure (MPESS) carriers in the center foreground is the United States (U.S.) Microgravity Payload 1 (USMP-1) with Space Acceleration Measurement System (SAMS), MEPHISTO (its French abbreviation), Lambda Point Experiment (LPE) cryostat assembly (identified by JPL insignia), and LPE vacuum maintenance assembly. Other payload bay (PLB) experiments visible in this image include: (on the starboard wall (left)) the Canadian Experiments 2 (CANEX-2) Space Vision System (SVS) Canadian Target Assembly (CTA) (foreground) and the Attitude Sensor Package (ASP);

STAR: an integrated solution to management and visualization of sequencing data.

PubMed

Wang, Tao; Liu, Jie; Shen, Li; Tonti-Filippini, Julian; Zhu, Yun; Jia, Haiyang; Lister, Ryan; Whitaker, John W; Ecker, Joseph R; Millar, A Harvey; Ren, Bing; Wang, Wei

2013-12-15

Easily visualization of complex data features is a necessary step to conduct studies on next-generation sequencing (NGS) data. We developed STAR, an integrated web application that enables online management, visualization and track-based analysis of NGS data. STAR is a multilayer web service system. On the client side, STAR leverages JavaScript, HTML5 Canvas and asynchronous communications to deliver a smoothly scrolling desktop-like graphical user interface with a suite of in-browser analysis tools that range from providing simple track configuration controls to sophisticated feature detection within datasets. On the server side, STAR supports private session state retention via an account management system and provides data management modules that enable collection, visualization and analysis of third-party sequencing data from the public domain with over thousands of tracks hosted to date. Overall, STAR represents a next-generation data exploration solution to match the requirements of NGS data, enabling both intuitive visualization and dynamic analysis of data. STAR browser system is freely available on the web at http://wanglab.ucsd.edu/star/browser and https://github.com/angell1117/STAR-genome-browser.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Winnek, D.F.

A method and apparatus for making X-ray photographs which can be viewed in three dimensions with the use of a lenticular screen. The apparatus includes a linear tomograph having a moving X-ray source on one side of a support on which an object is to be placed so that X-rays can pass through the object to the opposite side of the support. A movable cassette on the opposite side of the support moves in a direction opposite to the direction of travel of the X-ray source as the source moves relative to the support. The cassette has an intensifying screen,more » a grating mask provided with uniformly spaced slots for passing X-rays, a lenticular member adjacent to the mask, and a photographic emulsion adjacent to the opposite side of the lenticular member. The cassette has a power device for moving the lenticular member and the emulsion relative to the mask a distance equal to the spacing between a pair of adjacent slots in the mask. The X-rays from the source, after passing through an object on the support, pass into the cassette through the slots of the mask and are focused on the photographic emulsion to result in a continuum of X-ray views of the object. When the emulsion is developed and viewed through the lenticular member, the object can be seen in three dimensions.« less

Design Multi-Sides System Unmanned Surface Vehicle (USV) Rocket

NASA Astrophysics Data System (ADS)

Syam, Rafiudin; Sutresman, Onny; Mappaita, Abdullah; Amiruddin; Wiranata, Ardi

2018-02-01

This study aims to design and test USV multislide forms. This system is excellent for maneuvering on the x-y-z coordinates. The disadvantage of a single side USV is that it is very difficult to maneuver to achieve very dynamic targets. While for multi sides system easily maneuvered though x-y-z coordinates. In addition to security defense purposes, multi-side system is also good for maritime intelligence, surveillance. In this case, electric deducted fan with Multi-Side system so that the vehicle can still operate even in reverse condition. Multipleside USV experiments have done with good results. In a USV study designed to use two propulsions.

Wheat Response to Differences In Water and Nutritional Status Between Zeoponic and Hydroponic Growth Systems

NASA Technical Reports Server (NTRS)

Steinberg, Susan L.; Ming, Douglas W.; Henderson, Keith E.; Carrier, Chris; Gruener, John E.; Barta, Dan J.; Henninger, Don L.

1999-01-01

Hydroponic culture has traditionally been used for controlled environment life support systems (CELSS) because the optimal environment for roots supports high growth rates. Recent developments in zeoponic substrate and microporous tube irrigation (ZPT) also offer high control of the root environment. This study compared the effect of differences in water and nutrient status of ZPT or hydroponic culture on growth and yield of wheat (Triticum aestivum L., CV 'USU-Apogee'). In a side-by-side test in a controlled environment, wheat was grown in ZPT and recirculating hydroponics to maturity. Water use by plants grown in both culture systems peaked at 15-20 L per square meters per d up to day 40, after which it declined more rapidly for plants grown in ZPT culture due to earlier senescence of leaves. No consistent differences were noted in water status between plants grown in the two culture systems. Although yield was similar, harvest index was 28% lower for plants grown in ZPT versus hydroponic culture. Sterile green tillers made up 12% and 0% of the biomass of plants grown in ZPT and hydroponic culture, respectively. Differences in biomass partitioning were attributed primarily to NH4 -N nutrition of plants grown in ZPT as compared with NO3-N in hydroponic nutrient solution. It was likely that NH4-N induced Ca deficiency produced excess tillering and lower harvest index for plants grown in ZPT culture. These results suggest that further refinements in zeoponic substrate would make ZPT culture a viable alternative for achieving high productivity in a CELSS.

Wheat response to differences in water and nutritional status between zeoponic and hydroponic growth systems

NASA Technical Reports Server (NTRS)

Steinberg, S. L.; Ming, D. W.; Henderson, K. E.; Carrier, C.; Gruener, J. E.; Barta, D. J.; Henninger, D. L.

2000-01-01

Hydroponic culture has traditionally been used for controlled environment life support systems (CELSS) because the optimal environment for roots supports high growth rates. Recent developments in zeoponic substrate and microporous tube irrigation (ZPT) also offer high control of the root environment. This study compared the effect of differences in water and nutrient status of ZPT or hydroponic culture on growth and yield of wheat (Triticum aestivum L. cv. USU-Apogee). In a side-by-side test in a controlled environment, wheat was grown in ZPT and recirculating hydroponics to maturity. Water use by plants grown in both culture systems peaked at 15 to 20 L m-2 d-1 up to Day 40, after which it declined more rapidly for plants grown in ZPT culture due to earlier senescence of leaves. No consistent differences in water status were noted between plants grown in the two culture systems. Although yield was similar, harvest index was 28% lower for plants grown in ZPT than in hydroponic culture. Sterile green tillers made up 12 and 0% of the biomass of plants grown in ZPT and hydroponic culture, respectively. Differences in biomass partitioning were attributed primarily to NH4-N nutrition of plants grown in ZPT compared with NO3-N in hydroponic nutrient solution. It is probable that NH4-N-induced Ca deficiency produced excess tillering and lower harvest index for plants grown in ZPT culture. These results suggest that further refinements in zeoponic substrate would make ZPT culture a viable alternative for achieving high productivity in a CELSS.

Impact of adherence on the outcome of antiviral therapy for chronic hepatitis C.

PubMed

Mulhall, Brian P; Younossi, Zobair

2005-01-01

Nearly 4 million people in the United States have evidence of hepatitis C infection (HCV), representing a significant cause of cirrhosis and liver cancer as well a major burden to our healthcare systems and society. Antiviral therapy can successfully eradicate HCV over the long term, potentially reducing the risk of progression and improving patients' quality of life. The currently preferred HCV treatment is a combination of pegylated interferon alfa and ribavirin, which can achieve an overall sustained viral eradication rate of 55%. The duration of this treatment is typically determined by HCV genotype and the patient's early virologic response to the antiviral regimen. Evidence has accumulated over the past few years to indicate that close adherence to the optimal antiviral regimen can enhance sustained virologic response. But optimal treatment outcomes require diligence and careful management of side effects related to combination therapy. Although reducing the dose of pegylated interferon alfa, ribavirin, or both can effectively treat side effects, suboptimal doses of this regimen, especially ribavirin, may negatively affect virologic response. An alternative strategy is to use growth factors to treat cytopenias. This strategy can obviate dose reductions while potentially improving patients' quality of life. Patient support seems especially important early after the initiation of antiviral therapy. Encouraging study findings involving the growth factors, epoetin alfa and darbepoetin alfa, suggest improved anemia and quality of life while maintaining the optimal ribavirin dose. Future work should be aimed at providing stronger evidence for the use of these "supportive products" during anti-HCV therapy. As we strive to develop better treatment options for our HCV patients, the importance of adhering to the treatment regimen continues to play a central role. Effective side effect management is crucial for the success of this treatment because adherence is negatively affected by side effects related to the antiviral regimen. By identifying and addressing the important side effects of combination therapy for HCV, adherence to treatment can be improved and optimal outcomes can be achieved.

Right Ventricular Failure Post LVAD Implantation Corrected with Biventricular Support: An In Vitro Model.

PubMed

Shehab, Sajad; Allida, Sabine M; Davidson, Patricia M; Newton, Phillip J; Robson, Desiree; Jansz, Paul C; Hayward, Christopher S

Right ventricular failure after left ventricular assist device (LVAD) implantation is associated with high mortality. Management remains limited to pharmacologic therapy and temporary mechanical support. Delayed right ventricular assist device (RVAD) support after LVAD implantation is associated with poorer outcomes. With the advent of miniaturized, durable, continuous flow ventricular assist device systems, chronic RVAD and biventricular assist device (BiVAD) support has been used with some success. The purpose of this study was to assess combined BiVAD and LVAD with delayed RVAD support within a four-elemental mock circulatory loop (MCL) simulating the human cardiovascular system. Our hypothesis was that delayed continuous flow RVAD (RVAD) would produce similar hemodynamic and flow parameters to those of initial BiVAD support. Using the MCL, baseline biventricular heart failure with elevated right and left filling pressures with low cardiac output was simulated. The addition of LVAD within a biventricular configuration improved cardiac output somewhat, but was associated with persistent right heart failure with elevated right-sided filling pressures. The addition of an RVAD significantly improved LVAD outputs and returned filling pressures to normal throughout the circulation. In conclusion, RVAD support successfully restored hemodynamics and flow parameters of biventricular failure supported with isolated LVAD with persistent elevated right atrial pressure.

Evaluation of a dynamic arm support for seated and standing tasks: a laboratory study of electromyography and subjective feedback.

PubMed

Odell, Dan; Barr, Alan; Goldberg, Robert; Chung, Jeffrey; Rempel, David

2007-04-01

The goal of this study was to determine whether a new dynamic arm support system reduced shoulder and arm muscle load for seated and standing hand/ arm tasks. The new system provides support for both horizontal and vertical arm motion. A total of 11 participants performed ten tasks (five seated and five standing) both with and without the arm support. Outcomes were assessed with electromyography and subjective feedback. Muscle activity was measured over the dominant side supraspinatus, triceps and forearm extensor muscles. Significant (p < 0.01) reductions in static muscle activity were observed in one of ten tasks performed with the support device for the supraspinatus muscle, in five tasks for the triceps and in one task for forearm extensor muscles. Likewise, a significant improvement in subjective measures was reported with the support device for 'ease of task' for two of ten tasks, for 'forearm comfort' for three of ten tasks and for 'shoulder effort' for six of ten tasks. The results suggest that a dynamic forearm support may improve subjective comfort and reduce static muscle loads in the upper extremity for tasks that involve horizontal movement of the arms. For rapid motions, the value of the support is limited due to internal inertia and friction.

Dynamic surface electronic reconstruction as symmetry-protected topological orders in topological insulator Bi2Se3

NASA Astrophysics Data System (ADS)

Shu, G. J.; Liou, S. C.; Karna, S. K.; Sankar, R.; Hayashi, M.; Chou, F. C.

2018-04-01

The layered narrow-band-gap semiconductor Bi2Se3 is composed of heavy elements with strong spin-orbital coupling, which has been identified both as a good candidate for a thermoelectric material with high thermoelectric figure of merit (Z T ) and as a topological insulator of the Z2 type with a gapless surface band in a Dirac-cone shape. The existence of a conjugated π -bond system on the surface of each Bi2Se3 quintuple layer is proposed based on an extended valence bond model with valence electrons distributed in the hybridized orbitals. Supporting experimental evidence of a two-dimensional (2D) conjugated π -bond system on each quintuple layer of Bi2Se3 is provided using electron energy-loss spectroscopy and electron density mapping through inverse Fourier transform of x-ray diffraction data. Quantum chemistry calculations support the π -bond existence between partially filled 4 pz orbitals of Se via side-to-side orbital overlap positively. The conjugated π -bond system on the surface of each quintuple Bi2Se3 layer is proposed to be similar to that found in graphite (graphene) and responsible for the unique 2D conduction mechanism. The van der Waals (vdW) attractive force between quintuple layers is interpreted to be coming from the antiferroelectrically ordered effective electric dipoles, which are constructed with π -bond trimer pairs on Se layers across the vdW gap of minimized Coulomb repulsion.

Informatics in radiology: web-based preliminary reporting system for radiology residents with PACS integration.

PubMed

O'Connell, Timothy; Chang, Debra

2012-01-01

While on call, radiology residents review imaging studies and issue preliminary reports to referring clinicians. In the absence of an integrated reporting system at the training sites of the authors' institution, residents were typing and faxing preliminary reports. To partially automate the on-call resident workflow, a Web-based system for resident reporting was developed by using the free open-source xAMP Web application framework and an open-source DICOM (Digital Imaging and Communications in Medicine) software toolkit, with the goals of reducing errors and lowering barriers to education. This reporting system integrates with the picture archiving and communication system to display a worklist of studies. Patient data are automatically entered in the preliminary report to prevent identification errors and simplify the report creation process. When the final report for a resident's on-call study is available, the reporting system queries the report broker for the final report, and then displays the preliminary report side by side with the final report, thus simplifying the review process and encouraging review of all of the resident's reports. The xAMP Web application framework should be considered for development of radiology department informatics projects owing to its zero cost, minimal hardware requirements, ease of programming, and large support community.

Method of removing and detoxifying a phosphorus-based substance

DOEpatents

Vandegrift, G.F.; Steindler, M.J.

1985-05-21

A method of removing a phosphorus-based poisonous substance from water contaminated is presented. In addition, the toxicity of the phosphorus-based substance is also subsequently destroyed. A water-immiscible organic solvent is first immobilized on a supported liquid membrane before the contaminated water is contacted with one side of the supported liquid membrane to absorb the phosphorus-based substance in the organic solvent. The other side of the supported liquid membrane is contacted with a hydroxy-affording strong base to react with phosphorus-based solvated species to form a non-toxic product.

Sirocco Storage Server v. pre-alpha 0.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Curry, Matthew L.; Danielson, Geoffrey; Ward, H. Lee

Sirocco is a parallel storage system under development, designed for write-intensive workloads on large-scale HPC platforms. It implements a keyvalue object store on top of a set of loosely federated storage servers that cooperate to ensure data integrity and performance. It includes support for a range of different types of storage transactions. This software release constitutes a conformant storage server, along with the client-side libraries to access the storage over a network.

Fighting with Fires: The Future of Marine Corps Artillery

DTIC Science & Technology

1998-01-01

aircraft can be siphoned off for a multitude of other missions. The fielding of the Advanced Tactical Air Reconnaissance System ( ATARS ) for the F/A... psychologically .”81 With a well-balanced asymmetrical attack, we can rupture the enemy’s cohesion, and maintain our freedom of action. There is...the psychological impact of an artillery barrage (on both sides). The Marine Corps General Support Artillery Study was directed by the Secretary of

Computational Difficulties in the Identification and Optimization of Control Systems.

DTIC Science & Technology

1980-01-01

necessary and Identify by block number) - -. 3. iABSTRACT (Continue on revers, side It necessary and Identify by block number) As more realistic models ...Island 02912 ABSTRACT As more realistic models for resource management are developed, the need for efficient computational techniques for parameter...optimization (optimal control) in "state" models which This research was supported in part by ttfe National Science Foundation under grant NSF-MCS 79-05774

Management by Trajectory Trade Study of Roles and Responsibilities Between Participants and Automation Report

NASA Technical Reports Server (NTRS)

Fernandes, Alicia D.; Kaler, Curt; Leiden, Kenneth; Atkins, Stephen; Bell, Alan; Kilbourne, Todd; Evans, Mark

2017-01-01

This report describes a trade study of roles and responsibilities associated with the Management by Trajectory (MBT) concept. The MBT concept describes roles, responsibilities, and information and automation requirements for providing air traffic controllers and managers the ability to quickly generate, evaluate and implement changes to an aircraft's trajectory. In addition, the MBT concept describes mechanisms for imposing constraints on flight operator preferred trajectories only to the extent necessary to maintain safe and efficient traffic flows, and the concept provides a method for the exchange of trajectory information between ground automation systems and the aircraft that allows for trajectory synchronization and trajectory negotiation. The participant roles considered in this trade study include: airline dispatcher, flight crew, radar controller, traffic manager, and Air Traffic Control System Command Center (ATCSCC) traffic management specialists. The proposed allocation of roles and responsibilities was based on analysis of several use cases that were developed for this purpose as well as for walking through concept elements. The resulting allocation of roles and responsibilities reflects both increased automation capability to support many aviation functions, as well as increased flexibility to assign responsibilities to different participants - in many cases afforded by the increased automation capabilities. Note that the selection of participants to consider for allocation of each function is necessarily rooted in the current environment, in that MBT is envisioned as an evolution of the National Airspace System (NAS), and not a revolution. A key feature of the MBT allocations is a vision for the traffic management specialist to take on a greater role. This is facilitated by the vision that separation management functions, in addition to traffic management functions, will be carried out as trajectory management functions. This creates an opportunity for flexibility, allowing the traffic management specialist to carry out tasks that today can only be carried out by the controller currently in contact with the aircraft. This additional tasking for the traffic management specialist comes with requirements for workload management. An increased role for the Data-side (D-side) controller relative to the Radar-side (R-side) controller is a potential approach to mitigating workload for the traffic management specialist, as the D-side controller would have similar ability to perform separation management functions in what today might be considered the "trajectory management" timeframe. This analysis did not distinguish between the D-side and R-side controllers since in many cases the R-side controller works unassisted.

Aerodynamic results of a separation test (CA20) conducted at the Boeing transonic wind tunnel using 0.030-scale models of the configuration 140A/B (modified) SSV orbiter (model no. 45-0) and the Boeing 747 carrier (model no. AX 1319 I-1), volume 1. [wind tunnel tests

NASA Technical Reports Server (NTRS)

Dziubala, T.; Esparza, V.; Gillins, R. L.; Petrozzi, M.

1975-01-01

A Rockwell built 0.030-scale 45-0 modified Space Shuttle Orbiter Configuration 14?A/B model and a Boeing built 0.030-scale 747 carrier model were tested to provide six component force and moment data for each vehicle in proximity to the other at a matrix of relative positions, attitudes and test conditions (angles of attack and sideslip were varied). Orbiter model support system tare effects were determined for corrections to obtain support-free aerodynamics. In addition to the balance force data, pressures were measured. Pressure orifices were located at the base of the Orbiter, on either side of the vertical blade strut, and at the mid-root chord on either side of the vertical tail. Strain gages were installed on the Boeing 747 vertical tail to indicate buffet onset. Photographs of aerodynamic configurations tested are shown.

Right-side-stretched multifractal spectra indicate small-worldness in networks

NASA Astrophysics Data System (ADS)

Oświȩcimka, Paweł; Livi, Lorenzo; Drożdż, Stanisław

2018-04-01

Complex network formalism allows to explain the behavior of systems composed by interacting units. Several prototypical network models have been proposed thus far. The small-world model has been introduced to mimic two important features observed in real-world systems: i) local clustering and ii) the possibility to move across a network by means of long-range links that significantly reduce the characteristic path length. A natural question would be whether there exist several ;types; of small-world architectures, giving rise to a continuum of models with properties (partially) shared with other models belonging to different network families. Here, we take advantage of the interplay between network theory and time series analysis and propose to investigate small-world signatures in complex networks by analyzing multifractal characteristics of time series generated from such networks. In particular, we suggest that the degree of right-sided asymmetry of multifractal spectra is linked with the degree of small-worldness present in networks. This claim is supported by numerical simulations performed on several parametric models, including prototypical small-world networks, scale-free, fractal and also real-world networks describing protein molecules. Our results also indicate that right-sided asymmetry emerges with the presence of the following topological properties: low edge density, low average shortest path, and high clustering coefficient.

A ruthenium(II) complex inhibits tumor growth in vivo with fewer side-effects compared with cisplatin.

PubMed

Wang, Jin-Quan; Zhang, Ping-Yu; Ji, Liang-Nian; Chao, Hui

2015-05-01

The antitumor activity of a ruthenium(II) polypyridyl complex, Δ-[Ru(bpy)2(HPIP)](ClO4)2 (Δ-Ru1, where bpy=2,2'-bipyridine, HPIP=2-(2-hydroxyphenyl)imidazo[4,5-f][1,10]phenanthroline), was evaluated. The in vivo experiments showed that Δ-Ru1 inhibited the growth of a human cervical carcinoma cell line (HeLa) xenotransplanted into nude mice with efficiency similar to that of cisplatin. Histopathology examination of the tumors from treated xenograft models was consistent with apoptosis in tumor cells. Importantly, in striking contrast with cisplatin, Δ-Ru1 did not cause any detectable side effects on the kidney, liver, peripheral neuronal system, or the hematological system at the pharmacologically effective dose. The preclinical studies reported here provide support for the clinical use of Δ-Ru1 as an exciting new drug candidate with lower toxicity than cisplatin, endowed with proapoptotic properties. Copyright © 2015 Elsevier Inc. All rights reserved.

In-orbit performance of the ITOS improved attitude control system with Hall generator brushless motor and earth-splitting technique

NASA Technical Reports Server (NTRS)

Peacock, W. M.

1973-01-01

The National Aeronautics and Space Administration (NASA), launched ITOS-D with an improved attitude control system. A Hall generator brushless dc torque motor replaced the brush dc torque motor on Tiros-M and ITOS-A. Two CO2 attitude horizon sensors and one mirror replaced the four wideband horizon sensors and two mirrors on ITOS-1 and NOAA-1. Redundant pitch-control electronic boxes containing additional electronic circuitry for earth-splitting and brushless motor electronics were used. A method of generating a spacecraft earth-facing side reference for comparison to the time occurrence of the earth-splitting pulse was used to automatically correct pitch-attitude error. A single rotating flywheel, supported by a single bearing, provided gyroscopic stability and the required momentum interchange to keep one side of the satellite facing the earth. Magnetic torquing against the earth's magnetic field eliminated the requirement for expendable propellants which would limit satellite life in orbit.

Reflective all-sky thermal infrared cloud imager.

PubMed

Redman, Brian J; Shaw, Joseph A; Nugent, Paul W; Clark, R Trevor; Piazzolla, Sabino

2018-04-30

A reflective all-sky imaging system has been built using a long-wave infrared microbolometer camera and a reflective metal sphere. This compact system was developed for measuring spatial and temporal patterns of clouds and their optical depth in support of applications including Earth-space optical communications. The camera is mounted to the side of the reflective sphere to leave the zenith sky unobstructed. The resulting geometric distortion is removed through an angular map derived from a combination of checkerboard-target imaging, geometric ray tracing, and sun-location-based alignment. A tape of high-emissivity material on the side of the reflector acts as a reference that is used to estimate and remove thermal emission from the metal sphere. Once a bias that is under continuing study was removed, sky radiance measurements from the all-sky imager in the 8-14 μm wavelength range agreed to within 0.91 W/(m 2 sr) of measurements from a previously calibrated, lens-based infrared cloud imager over its 110° field of view.

Design of the 2D electron cyclotron emission imaging instrument for the J-TEXT tokamak.

PubMed

Pan, X M; Yang, Z J; Ma, X D; Zhu, Y L; Luhmann, N C; Domier, C W; Ruan, B W; Zhuang, G

2016-11-01

A new 2D Electron Cyclotron Emission Imaging (ECEI) diagnostic is being developed for the J-TEXT tokamak. It will provide the 2D electron temperature information with high spatial, temporal, and temperature resolution. The new ECEI instrument is being designed to support fundamental physics investigations on J-TEXT including MHD, disruption prediction, and energy transport. The diagnostic contains two dual dipole antenna arrays corresponding to F band (90-140 GHz) and W band (75-110 GHz), respectively, and comprises a total of 256 channels. The system can observe the same magnetic surface at both the high field side and low field side simultaneously. An advanced optical system has been designed which permits the two arrays to focus on a wide continuous region or two radially separate regions with high imaging spatial resolution. It also incorporates excellent field curvature correction with field curvature adjustment lenses. An overview of the diagnostic and the technical progress including the new remote control technique are presented.

Design of the 2D electron cyclotron emission imaging instrument for the J-TEXT tokamak

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pan, X. M.; Yang, Z. J., E-mail: yangzj@hust.edu.cn; Ma, X. D.

2016-11-15

A new 2D Electron Cyclotron Emission Imaging (ECEI) diagnostic is being developed for the J-TEXT tokamak. It will provide the 2D electron temperature information with high spatial, temporal, and temperature resolution. The new ECEI instrument is being designed to support fundamental physics investigations on J-TEXT including MHD, disruption prediction, and energy transport. The diagnostic contains two dual dipole antenna arrays corresponding to F band (90-140 GHz) and W band (75-110 GHz), respectively, and comprises a total of 256 channels. The system can observe the same magnetic surface at both the high field side and low field side simultaneously. An advancedmore » optical system has been designed which permits the two arrays to focus on a wide continuous region or two radially separate regions with high imaging spatial resolution. It also incorporates excellent field curvature correction with field curvature adjustment lenses. An overview of the diagnostic and the technical progress including the new remote control technique are presented.« less

Universal ripper miner

DOEpatents

Morrell, Roger J.; Larson, David A.

1991-01-01

A universal ripper miner used to cut, collect and transfer material from an underground mine working face includes a cutter head that is vertically movable in an arcuate cutting cycle by means of drive members, such as hydraulically actuated pistons. The cutter head may support a circular cutter bit having a circular cutting edge that may be indexed to incrementally expose a fresh cutting edge. An automatic indexing system is disclosed wherein indexing occurs by means of a worm gear and indexing lever mechanism. The invention also contemplates a bi-directional bit holder enabling cutting to occur in both the upstroke and the downstroke cutting cycle. Another feature of the invention discloses multiple bits arranged in an in-line, radially staggered pattern, or a side-by-side pattern to increase the mining capacity in each cutting cycle. An on-board resharpening system is also disclosed for resharpening the cutting edge at the end of cutting stroke position. The aforementioned improvement features may be used either singly, or in any proposed combination with each other.

Electric drive systems including smoothing capacitor cooling devices and systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dede, Ercan Mehmet; Zhou, Feng

An electric drive system includes a smoothing capacitor including at least one terminal, a bus bar electrically coupled to the at least one terminal, a thermoelectric device including a first side and a second side positioned opposite the first side, where the first side is thermally coupled to at least one of the at least one terminal and the bus bar, and a cooling element thermally coupled to the second side of the thermoelectric device, where the cooling element dissipates heat from the thermoelectric device.

Fuel cell assembly unit for promoting fluid service and electrical conductivity

DOEpatents

Jones, Daniel O.

1999-01-01

Fluid service and/or electrical conductivity for a fuel cell assembly is promoted. Open-faced flow channel(s) are formed in a flow field plate face, and extend in the flow field plate face between entry and exit fluid manifolds. A resilient gas diffusion layer is located between the flow field plate face and a membrane electrode assembly, fluidly serviced with the open-faced flow channel(s). The resilient gas diffusion layer is restrained against entering the open-faced flow channel(s) under a compressive force applied to the fuel cell assembly. In particular, a first side of a support member abuts the flow field plate face, and a second side of the support member abuts the resilient gas diffusion layer. The support member is formed with a plurality of openings extending between the first and second sides of the support member. In addition, a clamping pressure is maintained for an interface between the resilient gas diffusion layer and a portion of the membrane electrode assembly. Preferably, the support member is spikeless and/or substantially flat. Further, the support member is formed with an electrical path for conducting current between the resilient gas diffusion layer and position(s) on the flow field plate face.

Full pillar extraction at the Kathleen Mine with mobile roof supports

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grimm, E.S.

1994-12-31

The Voest Alpine Breaker Line Supports (ABLS) resemble self-propelled longwall shields. Each individual unit consists of four hydraulic legs extending from the base of the unit, pressing a solid flat canopy against the mine roof. Each support unit is capable of exerting 606 tons of force against the roof. A chain curtain on the sides and rear protects the interior of the support from falling rock. The internal scissoring lemniscate design allows for parallel movement of the canopy as it is raised or lowered. Each ABLS has 750 feet of 4 AWG trailing cable to supply 480 volts AC tomore » a permissible controller and a 40 hp explosion-proof electrical motor. The hydraulic pump and reservoir are self-contained and protected with an automatic fire suppression system.« less

Shuttle orbiter - IUS/DSP satellite interface contamination study

NASA Technical Reports Server (NTRS)

Rantanen, R. O.; Strange, D. A.

1978-01-01

The results of a contamination analysis on the Defense Support Program (DSP) satellite during launch and deployment by the Space Transportation System (STS) are presented. Predicted contaminant deposition was also included on critical DSP surfaces during the period soon after launch when the DSP is in the shuttle orbiter bay with the doors closed, the bay doors open, and during initial deployment. Additionally, a six sided box was placed at the spacecraft position to obtain directional contaminant flux information for a general payload while in the bay and during deployment. The analysis included contamination sources from the shuttle orbiter, IUS and cradle, the DSP sensor and the DSP support package.

Nuclear reactor having a polyhedral primary shield and removable vessel insulation

DOEpatents

Ekeroth, Douglas E.; Orr, Richard

1993-01-01

A nuclear reactor is provided having a generally cylindrical reactor vessel disposed within an opening in a primary shield. The opening in the primary shield is defined by a plurality of generally planar side walls forming a generally polyhedral-shaped opening. The reactor vessel is supported within the opening in the primary shield by reactor vessel supports which are in communication and aligned with central portions of some of the side walls. The reactor vessel is connected to the central portions of the reactor vessel supports. A thermal insulation polyhedron formed from a plurality of slidably insertable and removable generally planar insulation panels substantially surrounds at least a portion of the reactor vessel and is disposed between the reactor vessel and the side walls of the primary shield. The shape of the insulation polyhedron generally corresponds to the shape of the opening in the primary shield. Reactor monitoring instrumentation may be mounted in the corners of the opening in the primary shield between the side walls and the reactor vessel such that insulation is not disposed between the instrumentation and the reactor vessel.

Nuclear reactor having a polyhedral primary shield and removable vessel insulation

DOEpatents

Ekeroth, D.E.; Orr, R.

1993-12-07

A nuclear reactor is provided having a generally cylindrical reactor vessel disposed within an opening in a primary shield. The opening in the primary shield is defined by a plurality of generally planar side walls forming a generally polyhedral-shaped opening. The reactor vessel is supported within the opening in the primary shield by reactor vessel supports which are in communication and aligned with central portions of some of the side walls. The reactor vessel is connected to the central portions of the reactor vessel supports. A thermal insulation polyhedron formed from a plurality of slidably insertable and removable generally planar insulation panels substantially surrounds at least a portion of the reactor vessel and is disposed between the reactor vessel and the side walls of the primary shield. The shape of the insulation polyhedron generally corresponds to the shape of the opening in the primary shield. Reactor monitoring instrumentation may be mounted in the corners of the opening in the primary shield between the side walls and the reactor vessel such that insulation is not disposed between the instrumentation and the reactor vessel. 5 figures.

Effect of supplemented and topically applied antioxidant substances on human tissue.

PubMed

Darvin, M; Zastrow, L; Sterry, W; Lademann, J

2006-01-01

Systemic and topical application of antioxidant substances for the medical treatment and prophylaxis of many diseases as well as additional protection of the skin against the destructive action of free radicals and other reactive species has become very popular during the past years. Stimulated by the positive results of a fruit and vegetable diet in supporting medical treatment and in cosmetics, artificial and extracted antioxidant substances have been broadly applied. Surprisingly, not only positive but also strong negative results have been obtained by different authors. According to study reports artificial and extracted antioxidant substances support different kinds of medical therapies, if they are applied in mixtures of different compounds at low concentration levels. In the case of the application of high concentration of some single compounds, side effects were often observed. Regarding skin treatment by systemically applied antioxidant substances for cosmetic purposes, positive cosmetic effects as well as no effects, but almost no side effects, apart from a number of allergic reactions, were reported. One reason for this seems to be the lower concentration of systemically applied antioxidant substances in comparison with a medical application. Topical application of antioxidant substances is closely related to cosmetic treatment for skin protection and anti-aging. Positive results were also obtained in this case. The present review is an attempt to classify and summarize the published literature concerning the efficiency of action of systemic and topical applications of antioxidant substances, such as carotenoids and vitamins, on human organism and especially on the skin. The available literature on this topic is very extensive and the results are often contradictory. Nevertheless, there are some clear tendencies concerning systemic and topical application of antioxidant substances in medicine and cosmetics, and we summarize them in the present paper.

CropEx Web-Based Agricultural Monitoring and Decision Support

NASA Technical Reports Server (NTRS)

Harvey. Craig; Lawhead, Joel

2011-01-01

CropEx is a Web-based agricultural Decision Support System (DSS) that monitors changes in crop health over time. It is designed to be used by a wide range of both public and private organizations, including individual producers and regional government offices with a vested interest in tracking vegetation health. The database and data management system automatically retrieve and ingest data for the area of interest. Another stores results of the processing and supports the DSS. The processing engine will allow server-side analysis of imagery with support for image sub-setting and a set of core raster operations for image classification, creation of vegetation indices, and change detection. The system includes the Web-based (CropEx) interface, data ingestion system, server-side processing engine, and a database processing engine. It contains a Web-based interface that has multi-tiered security profiles for multiple users. The interface provides the ability to identify areas of interest to specific users, user profiles, and methods of processing and data types for selected or created areas of interest. A compilation of programs is used to ingest available data into the system, classify that data, profile that data for quality, and make data available for the processing engine immediately upon the data s availability to the system (near real time). The processing engine consists of methods and algorithms used to process the data in a real-time fashion without copying, storing, or moving the raw data. The engine makes results available to the database processing engine for storage and further manipulation. The database processing engine ingests data from the image processing engine, distills those results into numerical indices, and stores each index for an area of interest. This process happens each time new data is ingested and processed for the area of interest, and upon subsequent database entries, the database processing engine qualifies each value for each area of interest and conducts a logical processing of results indicating when and where thresholds are exceeded. Reports are provided at regular, operator-determined intervals that include variances from thresholds and links to view raw data for verification, if necessary. The technology and method of development allow the code base to easily be modified for varied use in the real-time and near-real-time processing environments. In addition, the final product will be demonstrated as a means for rapid draft assessment of imagery.

Teaching Normal Birth Interactively

PubMed Central

Hotelling, Barbara A.

2004-01-01

In this column, the author provides examples of teaching strategies that childbirth educators may utilize to illustrate each of the six care practices supported by Lamaze International to promote normal birth: labor begins on its own, freedom of movement throughout labor, continuous labor support, no routine interventions, non-supine (e.g., upright or side-lying) positions for birth, and no separation of mother and baby with unlimited opportunity for breastfeeding. PMID:17273389

Osteoblast and osteoclast behaviors in the turnover of attachment bones during medaka tooth replacement.

PubMed

Mantoku, Akiko; Chatani, Masahiro; Aono, Kazushi; Inohaya, Keiji; Kudo, Akira

2016-01-15

Tooth replacement in polyphyodont is a well-organized system for maintenance of homeostasis of teeth, containing the dynamic structural change in skeletal tissues such as the attachment bone, which is the supporting element of teeth. Histological analyses have revealed the character of tooth replacement, however, the cellular mechanism of how skeletal tissues are modified during tooth replacement is largely unknown. Here, we showed the important role of osteoblasts for controlling osteoclasts to modify the attachment bone during tooth replacement in medaka pharyngeal teeth, coupled with an osterix-DsRed/TRAP-GFP transgenic line to visualize osteoblasts and osteoclasts. In the turnover of the row of attachment bones, these bones were resorbed at the posterior side where most developed functional teeth were located, and generated at the anterior side where teeth were newly erupted, which caused continuous tooth replacement. In the cellular analysis, osteoclasts and osteoblasts were located at attachment bones separately, since mature osteoclasts were localized at the resorbing side and osteoblasts gathered at the generating side. To demonstrate the role of osteoclasts in tooth replacement, we established medaka made deficient in c-fms-a by TALEN. c-fms-a deficient medaka showed hyperplasia of attachment bones along with reduced bone resorption accompanied by a low number of TRAP-positive osteoclasts, indicating an important role of osteoclasts in the turnover of attachment bones. Furthermore, nitroreductase-mediated osteoblast-specific ablation induced disappearance of osteoclasts, indicating that osteoblasts were essential for maintenance of osteoclasts for the proper turnover. Taken together, our results suggested that the medaka attachment bone provides the model to understand the cellular mechanism for tooth replacement, and that osteoblasts act in the coordination of bone morphology by supporting osteoclasts. Copyright © 2015 Elsevier Inc. All rights reserved.

J-2X Turbopump Cavitation Diagnostics

NASA Technical Reports Server (NTRS)

Santi, I. Michael; Butas, John P.; Tyler, Thomas R., Jr.; Aguilar, Robert; Sowers, T. Shane

2010-01-01

The J-2X is the upper stage engine currently being designed by Pratt & Whitney Rocketdyne (PWR) for the Ares I Crew Launch Vehicle (CLV). Propellant supply requirements for the J-2X are defined by the Ares Upper Stage to J-2X Interface Control Document (ICD). Supply conditions outside ICD defined start or run boxes can induce turbopump cavitation leading to interruption of J-2X propellant flow during hot fire operation. In severe cases, cavitation can lead to uncontained engine failure with the potential to cause a vehicle catastrophic event. Turbopump and engine system performance models supported by system design information and test data are required to predict existence, severity, and consequences of a cavitation event. A cavitation model for each of the J-2X fuel and oxidizer turbopumps was developed using data from pump water flow test facilities at Pratt & Whitney Rocketdyne (PWR) and Marshall Space Flight Center (MSFC) together with data from Powerpack 1A testing at Stennis Space Center (SSC) and from heritage systems. These component models were implemented within the PWR J-2X Real Time Model (RTM) to provide a foundation for predicting system level effects following turbopump cavitation. The RTM serves as a general failure simulation platform supporting estimation of J-2X redline system effectiveness. A study to compare cavitation induced conditions with component level structural limit thresholds throughout the engine was performed using the RTM. Results provided insight into system level turbopump cavitation effects and redline system effectiveness in preventing structural limit violations. A need to better understand structural limits and redline system failure mitigation potential in the event of fuel side cavitation was indicated. This paper examines study results, efforts to mature J-2X turbopump cavitation models and structural limits, and issues with engine redline detection of cavitation and the use of vehicle-side abort triggers to augment the engine redline system.

A Standards-Based Architecture Proposal for Integrating Patient mHealth Apps to Electronic Health Record Systems.

PubMed

Marceglia, S; Fontelo, P; Rossi, E; Ackerman, M J

2015-01-01

Mobile health Applications (mHealth Apps) are opening the way to patients' responsible and active involvement with their own healthcare management. However, apart from Apps allowing patient's access to their electronic health records (EHRs), mHealth Apps are currently developed as dedicated "island systems". Although much work has been done on patient's access to EHRs, transfer of information from mHealth Apps to EHR systems is still low. This study proposes a standards-based architecture that can be adopted by mHealth Apps to exchange information with EHRs to support better quality of care. Following the definition of requirements for the EHR/mHealth App information exchange recently proposed, and after reviewing current standards, we designed the architecture for EHR/mHealth App integration. Then, as a case study, we modeled a system based on the proposed architecture aimed to support home monitoring for congestive heart failure patients. We simulated such process using, on the EHR side, OpenMRS, an open source longitudinal EHR and, on the mHealth App side, the iOS platform. The integration architecture was based on the bi-directional exchange of standard documents (clinical document architecture rel2 - CDA2). In the process, the clinician "prescribes" the home monitoring procedures by creating a CDA2 prescription in the EHR that is sent, encrypted and de-identified, to the mHealth App to create the monitoring calendar. At the scheduled time, the App alerts the patient to start the monitoring. After the measurements are done, the App generates a structured CDA2-compliant monitoring report and sends it to the EHR, thus avoiding local storage. The proposed architecture, even if validated only in a simulation environment, represents a step forward in the integration of personal mHealth Apps into the larger health-IT ecosystem, allowing the bi-directional data exchange between patients and healthcare professionals, supporting the patient's engagement in self-management and self-care.

29 CFR 1915.507 - Land-side fire protection systems.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 7 2013-07-01 2013-07-01 false Land-side fire protection systems. 1915.507 Section 1915... Protection in Shipyard Employment § 1915.507 Land-side fire protection systems. (a) Employer responsibilities. The employer must ensure all fixed and portable fire protection systems needed to meet an OSHA...

29 CFR 1915.507 - Land-side fire protection systems.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 7 2012-07-01 2012-07-01 false Land-side fire protection systems. 1915.507 Section 1915... Protection in Shipyard Employment § 1915.507 Land-side fire protection systems. (a) Employer responsibilities. The employer must ensure all fixed and portable fire protection systems needed to meet an OSHA...

29 CFR 1915.507 - Land-side fire protection systems.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 7 2011-07-01 2011-07-01 false Land-side fire protection systems. 1915.507 Section 1915... Protection in Shipyard Employment § 1915.507 Land-side fire protection systems. (a) Employer responsibilities. The employer must ensure all fixed and portable fire protection systems needed to meet an OSHA...

29 CFR 1915.507 - Land-side fire protection systems.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 7 2014-07-01 2014-07-01 false Land-side fire protection systems. 1915.507 Section 1915... Protection in Shipyard Employment § 1915.507 Land-side fire protection systems. (a) Employer responsibilities. The employer must ensure all fixed and portable fire protection systems needed to meet an OSHA...

29 CFR 1915.507 - Land-side fire protection systems.

Code of Federal Regulations, 2010 CFR

2010-07-01

... specific recommendations in NFPA 14-2003 Standard for the Installation of Standpipe and Hose Systems... 29 Labor 7 2010-07-01 2010-07-01 false Land-side fire protection systems. 1915.507 Section 1915... Protection in Shipyard Employment § 1915.507 Land-side fire protection systems. (a) Employer responsibilities...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Madin, Mark Michael; Wicks, Christopher Donald

A cam carrier assembly includes a body made of a material lighter than aluminum. The body has a first side operably coupled with a cylinder head and a second side having bearing surfaces with bearing inserts. The bearing inserts support the camshaft. A series of apertures extend between the first and second sides of the body. Lobes of the camshaft operably couple with the valves of the cylinder head through the series of apertures extending between the first and second sides of the body.

Exposure to benevolent sexism and complementary gender stereotypes: consequences for specific and diffuse forms of system justification.

PubMed

Jost, John T; Kay, Aaron C

2005-03-01

Many have suggested that complementary gender stereotypes of men as agentic (but not communal) and women as communal (but not agentic) serve to increase system justification, but direct experimental support has been lacking. The authors exposed people to specific types of gender-related beliefs and subsequently asked them to complete measures of gender-specific or diffuse system justification. In Studies 1 and 2, activating (a) communal or complementary (communal + agentic) gender stereotypes or (b) benevolent or complementary (benevolent + hostile) sexist items increased support for the status quo among women. In Study 3, activating stereotypes of men as agentic also increased system justification among men and women, but only when women's characteristics were associated with higher status. Results suggest that complementary stereotypes psychologically offset the one-sided advantage of any single group and contribute to an image of society in which everyone benefits through a balanced dispersion of benefits. ((c) 2005 APA, all rights reserved).

A usability study of CPOE's medication administration functions: impact on physician-nurse cooperation.

PubMed

Beuscart-Zéphir, Marie Catherine; Pelayo, Sylvia; Degoulet, Patrice; Anceaux, Françoise; Guerlinger, Sandra; Meaux, Jean-Jacques

2004-01-01

Implementation of CPOE systems in Healthcare Institutions has proven efficient in reducing medication errors but it also induces hidden side-effects on Doctor-Nurse cooperation. We propose a usability engineering approach to this problem. An extensive activity analysis of the medication ordering and administration process was performed in several departments of 3 different hospitals. Two of these hospitals are still using paper-based orders, while the 3rd one is in the roll-out phase of medication functions of its CPOE system. We performed a usability assessment of this CPOE system. The usability assessment uncovered usability problems for the entry of medication administration time scheduling by the physician and revealed that the information can be ambiguous for the nurse. The comparison of cooperation models in both situation shows that users tend to adopt a distributed decision making paradigm in the paper-based situation, while the CPOE system supports a centralized decision making process. This analysis can support recommendation for the re-engineering of the Human-Computer Interface.

Modulation of phase durations, phase variations, and temporal coordination of the four limbs during quadrupedal split-belt locomotion in intact adult cats

PubMed Central

D'Angelo, Giuseppe; Thibaudier, Yann; Telonio, Alessandro; Hurteau, Marie-France; Kuczynski, Victoria; Dambreville, Charline

2014-01-01

Stepping along curvilinear paths produces speed differences between the inner and outer limb(s). This can be reproduced experimentally by independently controlling left and right speeds with split-belt locomotion. Here we provide additional details on the pattern of the four limbs during quadrupedal split-belt locomotion in intact cats. Six cats performed tied-belt locomotion (same speed bilaterally) and split-belt locomotion where one side (constant side) stepped at constant treadmill speed while the other side (varying side) stepped at several speeds. Cycle, stance, and swing durations changed in parallel in homolateral limbs with shorter and longer stance and swing durations on the fast side, respectively, compared with the slow side. Phase variations were quantified in all four limbs by measuring the slopes of the regressions between stance and cycle durations (rSTA) and between swing and cycle durations (rSW). For a given limb, rSTA and rSW were not significantly different from one another on the constant side whereas on the varying side rSTA increased relative to tied-belt locomotion while rSW became more negative. Phase variations were similar for homolateral limbs. Increasing left-right speed differences produced a large increase in homolateral double support on the slow side, while triple-support periods decreased. Increasing left-right speed differences altered homologous coupling, homolateral coupling on the fast side, and coupling between the fast hindlimb and slow forelimb. Results indicate that homolateral limbs share similar control strategies, only certain features of the interlimb pattern adjust, and spinal locomotor networks of the left and right sides are organized symmetrically. PMID:25031257

View from underneath bridge on west side shows cantilevered steel ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View from underneath bridge on west side shows cantilevered steel supports for sidewalk above. - Raging River Bridge No. 234A, Preston-Fall City Road & Southeast Forty-fourth Place, Fall City, King County, WA

Pleated metal bipolar assembly

DOEpatents

Wilson, Mahlon S.; Zawodzinski, Christine

2001-01-01

A thin low-cost bipolar plate for an electrochemical cell is formed from a polymer support plate with first flow channels on a first side of the support plate and second flow channels on a second side of the support plate, where the first flow channels and second flow channels have intersecting locations and have a depth effective to form openings through the support plate at the intersecting locations. A first foil of electrically conductive material is pressed into the first flow channels. A second foil of electrically conductive material pressed into the second flow channels so that electrical contact is made between the first and second foils at the openings through the support plate. A particular application of the bipolar plate is in polymer electrolyte fuel cells.

Open Education as a Way for Space Education in Russia

NASA Astrophysics Data System (ADS)

Malyshev, V. V.; Karp, K. A.

2002-01-01

low level of state financial support. As a result there is a decreasing education quality. Scientific research was always an integral part of education and an alternative way for education financial support. But today the level of such support is too low as well. High experience of Russian space education system is not useful completely. This paper shows, that at present an open education could be a new step of space education in Russia. discussed in the paper. of students per one professor and also the number of students, which pay for education. New technology based on Internet technology would provide high methodology and technical level of education. The open education guarantees training in different areas and specialties on international standard level. education process, new education technology, new equipment of education system, new ways of financial support, international cooperation in education process, new professors and staffs in education system, increasing the level of salary for staff and comfortable conditions for students are discussed at the first. free education period, both traditional and new education methods are very important on the other side. about 4-5 years. The necessity of international educational system integration has to be taken into account. The international standard request, educational courses in different languages and free market conditions have to be under consideration. The partially ready open space education is discussed also. That system can be started even today.

Embodied collaboration support system for 3D shape evaluation in virtual space

NASA Astrophysics Data System (ADS)

Okubo, Masashi; Watanabe, Tomio

2005-12-01

Collaboration mainly consists of two tasks; one is each partner's task that is performed by the individual, the other is communication with each other. Both of them are very important objectives for all the collaboration support system. In this paper, a collaboration support system for 3D shape evaluation in virtual space is proposed on the basis of both studies in 3D shape evaluation and communication support in virtual space. The proposed system provides the two viewpoints for each task. One is the viewpoint of back side of user's own avatar for the smooth communication. The other is that of avatar's eye for 3D shape evaluation. Switching the viewpoints satisfies the task conditions for 3D shape evaluation and communication. The system basically consists of PC, HMD and magnetic sensors, and users can share the embodied interaction by observing interaction between their avatars in virtual space. However, the HMD and magnetic sensors, which are put on the users, would restrict the nonverbal communication. Then, we have tried to compensate the loss of nodding of partner's avatar by introducing the speech-driven embodied interactive actor InterActor. Sensory evaluation by paired comparison of 3D shapes in the collaborative situation in virtual space and in real space and the questionnaire are performed. The result demonstrates the effectiveness of InterActor's nodding in the collaborative situation.

STS-31 Hubble Space Telescope (HST) pre-deployment procedures aboard OV-103

NASA Image and Video Library

1990-04-24

During STS-31, the Hubble Space Telescope (HST) grappled by the remote manipulator system (RMS) end effector is held in appendage deploy position above Discovery, Orbiter Vehicle (OV) 103. The solar array (SA) bistem cassette has been released from its latch fittings. The bistem spreader bars begin to unfurl the SA wing. The secondary deployment mechanism (SDM) handle is visible at the SA end. Stowed against either side of the HST System Support Module (SSM) forward shell are the high-gain antennae (HGA). Puerto Rico and the Dominican Republic are recognizable at the left of the frame.

Platform C South Arrival

NASA Image and Video Library

2016-08-05

The second section of the first half of the C-level work platforms, C South, for NASA’s Space Launch System (SLS) rocket was offloaded from a heavy transport truck in a staging area on the west side of the Vehicle Assembly Building (VAB) at the agency’s Kennedy Space Center in Florida. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft and provide access for testing and processing.

A tissue-like culture system using microstructures: influence of extracellular matrix material on cell adhesion and aggregation.

PubMed

Knedlitschek, G; Schneider, F; Gottwald, E; Schaller, T; Eschbach, E; Weibezahn, K F

1999-02-01

Special microenvironmental conditions are required to induce and/or maintain specific qualities of differentiated cells. An important parameter is the three-dimensional tissue architecture that cannot be reproduced in conventional monolayer systems. Advanced tissue culture systems will meet many of these demands, but may reach their limits, especially when gradients of specific substances over distinct tissue layers must be established for long-term culture. These limitations may be overcome by incorporating microstructures into tissue-like culture systems. The microstructured cell support presented consists of a flat array of 625 cubic microcontainers with porous bottoms, in which cells can be supplied with specific media from both sides of the tissue layer. Permanent cell lines and primary rat hepatocytes have been used to test the culture system. In order to define reproducible conditions for tissue formation and for cell adherence to the structure, several ECM (extracellular matrix) components were tested for coating of microstructured substrata. The described tissue culture system offers great flexibility in adapting the cell support to specific needs.

An Ontology-Based, Mobile-Optimized System for Pharmacogenomic Decision Support at the Point-of-Care

PubMed Central

Miñarro-Giménez, Jose Antonio; Blagec, Kathrin; Boyce, Richard D.; Adlassnig, Klaus-Peter; Samwald, Matthias

2014-01-01

Background The development of genotyping and genetic sequencing techniques and their evolution towards low costs and quick turnaround have encouraged a wide range of applications. One of the most promising applications is pharmacogenomics, where genetic profiles are used to predict the most suitable drugs and drug dosages for the individual patient. This approach aims to ensure appropriate medical treatment and avoid, or properly manage, undesired side effects. Results We developed the Medicine Safety Code (MSC) service, a novel pharmacogenomics decision support system, to provide physicians and patients with the ability to represent pharmacogenomic data in computable form and to provide pharmacogenomic guidance at the point-of-care. Pharmacogenomic data of individual patients are encoded as Quick Response (QR) codes and can be decoded and interpreted with common mobile devices without requiring a centralized repository for storing genetic patient data. In this paper, we present the first fully functional release of this system and describe its architecture, which utilizes Web Ontology Language 2 (OWL 2) ontologies to formalize pharmacogenomic knowledge and to provide clinical decision support functionalities. Conclusions The MSC system provides a novel approach for enabling the implementation of personalized medicine in clinical routine. PMID:24787444

An ontology-based, mobile-optimized system for pharmacogenomic decision support at the point-of-care.

PubMed

Miñarro-Giménez, Jose Antonio; Blagec, Kathrin; Boyce, Richard D; Adlassnig, Klaus-Peter; Samwald, Matthias

2014-01-01

The development of genotyping and genetic sequencing techniques and their evolution towards low costs and quick turnaround have encouraged a wide range of applications. One of the most promising applications is pharmacogenomics, where genetic profiles are used to predict the most suitable drugs and drug dosages for the individual patient. This approach aims to ensure appropriate medical treatment and avoid, or properly manage, undesired side effects. We developed the Medicine Safety Code (MSC) service, a novel pharmacogenomics decision support system, to provide physicians and patients with the ability to represent pharmacogenomic data in computable form and to provide pharmacogenomic guidance at the point-of-care. Pharmacogenomic data of individual patients are encoded as Quick Response (QR) codes and can be decoded and interpreted with common mobile devices without requiring a centralized repository for storing genetic patient data. In this paper, we present the first fully functional release of this system and describe its architecture, which utilizes Web Ontology Language 2 (OWL 2) ontologies to formalize pharmacogenomic knowledge and to provide clinical decision support functionalities. The MSC system provides a novel approach for enabling the implementation of personalized medicine in clinical routine.

MANIPULATOR FOR SLAVE ROBOT

DOEpatents

Goertz, R.C.; Grimson, J.H.; Kohut, F.A.

1961-04-01

A remote-control manipulator comprising two stationary master units, two slave units on a movable vehicle, and electrical connections between the master and slave units is reported. The slave units are side by side with a minimum over-all width, which is made feasible by an arrangement of transducers producing most movements of each slave unit to one side of the support of said slave unit.

The design of a wireless batteryless biflash installation with high power LEDs

NASA Astrophysics Data System (ADS)

Cappelle, J.; De Geest, W.; Hanselaer, P.

2011-05-01

Adding flashlights at crosswalks may make these weak traffic points safer. Unfortunately plugging in traffic lights into the electrical grid is expensive and complex. This paper reports about the energetic, the electronic and the optical design and building of a wireless and batteryless biflash installation in the framework of a flemish SME supporting program. The energy is supplied by a small solar panel and is buffered by supercapacitors instead of batteries. This has the advantage of being maintenance free: the number of charge-discharge cycles is almost unlimited because there is no chemical reaction involved in the storage mechanism. On the other hand the limited energy storage capacity of supercapacitors requires a new approach for the system design. Based on the EN-12352 standard for warning light devices, all design choices were filled in to be as energy efficient as possible. The duty cycle and the light output of the high power led flashlights are minimized. The components for the electronic circuits for the led driver, the control and the RF communication are selected based on their energy consumption and power management techniques are implemented. A lot of energy is saved by making the biflash system active. The leds are only flashing on demand or at preprogrammed moments. A biflash installation is typically installed at both sides of a crosswalk. A call at one of the sides should result in flashing at both sides. To maintain the drag and drop principle, a wireless RF communication system is designed.

OVERVIEW OF VALVE TOWER FROM EASTERN SIDE OF BASIN SHOWING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

OVERVIEW OF VALVE TOWER FROM EASTERN SIDE OF BASIN SHOWING BRIDGE SUPPORTS ON HILLTOP. VIEW FACING WEST - Schofield Barracks Military Reservation, Ku Tree Reservoir, Valve Tower, Kalakoa Stream, East Range, Wahiawa, Honolulu County, HI

Seismological Discrimination and Yield Determination Research

DTIC Science & Technology

1980-02-01

observed short period vertical seismograms for a * Rainier Mesa explosion ....... . .68 iv * LIST OF ILLUSTRATIONS (continued) Figure Page 33. Comparison... mounted on sides 2 and 4. All signals were recorded on a FM instrumenta- tion tape machine with response from dc to 80 kHz. All the charges in each grout...detail. (Probes * were mounted on an external support and held at a nominal 0.2 mm from the Al disks.) 81 SYSTEMS. SCIENCE’ AND SOFT WARE 5.3 RESULTS

Web Application Design Using Server-Side JavaScript

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hampton, J.; Simons, R.

1999-02-01

This document describes the application design philosophy for the Comprehensive Nuclear Test Ban Treaty Research & Development Web Site. This design incorporates object-oriented techniques to produce a flexible and maintainable system of applications that support the web site. These techniques will be discussed at length along with the issues they address. The overall structure of the applications and their relationships with one another will also be described. The current problems and future design changes will be discussed as well.

52. View from ground level showing lower radar scanner switch ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

52. View from ground level showing lower radar scanner switch with open port door in radar scanner building 105 showing emanating waveguides from lower switch in vertical run; photograph also shows catwalk to upper scanner switch in upper left side of photograph and structural supports. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

City of San Antonio, Texas Better Buildings Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyer, Liza C.; Hammer, Mary C.

2014-06-30

The San Antonio Better Buildings Program is a unified single-point-of-service energy efficiency delivery mechanism targeting residential, commercial, institutional, industrial and public buildings. This comprehensive and replicable energy efficiency program is designed to be an effective demand side management initiative to provide a seamless process for program participants to have turn-key access to expert analysis, support and incentives to improve the performance of their in-place energy using systems, while reducing electrical energy use and demand.

Wetland Flow and Salinity Budgets and Elements of a Decision Support System toward Implementation of Real-Time Seasonal Wetland Salinity Management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quinn, N.W.T.; Ortega, R.; Rahilly, P.

2011-12-17

The project has provided science-based tools for the long-term management of salinity in drainage discharges from wetlands to the San Joaquin River. The results of the project are being used to develop best management practices (BMP) and a decision support system to assist wetland managers adjust the timing of salt loads delivered to the San Joaquin River during spring drawdown. Adaptive drainage management scheduling has the potential to improve environmental compliance with salinity objectives in the Lower San Joaquin River by reducing the frequency of violation of Vernalis salinity standards, especially in dry and critically dry years. The paired approachmore » to project implementation whereby adaptively managed and traditional practices were monitored in a side-by-side fashion has provided a quantitative measure of the impacts of the project on the timing of salt loading to the San Joaquin River. The most significant accomplishments of the project has been the technology transfer to wetland biologists, ditch tenders and water managers within the Grasslands Ecological Area. This “learning by doing” has build local community capacity within the Grassland Water District and California Department of Fish and Game providing these institutions with new capability to assess and effectively manage salinity within their wetlands while simultaneously providing benefits to salinity management of the San Joaquin River.« less

Effects of different heel-raise-lower exercise interventions on the strength of plantarflexion, balance, and gait parameters in stroke survivors.

PubMed

Lee, Seung-Mi; Cynn, Heon-Seock; Yoon, Tae-Lim; Lee, Ji-Hyun

2017-09-01

The objective of this study was to investigate the effects of Heel-Raise-Lower Exercise (HRLE) interventions on the strength of plantarflexion, balance, and gait parameters in people with stroke. Specifically, this study compared the two different HRLEs to identify whether heels raise-lower with forefoot on a block (HRB) is more effective or ineffective to enhance strength and functional capacities than heels raise-lower on a level floor (HRL) exercise in people with stroke. Repetitive heel raise-lower is a common exercise for improving the strength and power of ankle plantarflexors. It is a simple movement, requires no equipment, and can be performed at home. Each group of 10 people with stroke was given either HRB training or HRL training. The subjects performed the exercise 100 times per day, 5 days per week for 6 weeks. The strength of plantarflexors, static/dynamic balance, and gait parameters were measured using the manual muscle test (MMT), a Biodex Balance System (BBS) SD, and the GAITRite system. After 6 weeks of treatment, there were significant increases in the plantarflexors strength in both groups: by 34% in the HRB group and by 21% in the HRL group. Static and dynamic balance and gait speed also increased significantly in both groups. However, cadence, the paretic side single limb support period (SLSP), paretic side step length, and paretic side stride length significantly increased only in the HRB group. The HRB improved significantly the plantar flexor strength of the paretic side, gait speed, and cadence compared to the HRL.

Modeling and Analysis of Commercial Building Electrical Loads for Demand Side Management

NASA Astrophysics Data System (ADS)

Berardino, Jonathan

In recent years there has been a push in the electric power industry for more customer involvement in the electricity markets. Traditionally the end user has played a passive role in the planning and operation of the power grid. However, many energy markets have begun opening up opportunities to consumers who wish to commit a certain amount of their electrical load under various demand side management programs. The potential benefits of more demand participation include reduced operating costs and new revenue opportunities for the consumer, as well as more reliable and secure operations for the utilities. The management of these load resources creates challenges and opportunities to the end user that were not present in previous market structures. This work examines the behavior of commercial-type building electrical loads and their capacity for supporting demand side management actions. This work is motivated by the need for accurate and dynamic tools to aid in the advancement of demand side operations. A dynamic load model is proposed for capturing the response of controllable building loads. Building-specific load forecasting techniques are developed, with particular focus paid to the integration of building management system (BMS) information. These approaches are tested using Drexel University building data. The application of building-specific load forecasts and dynamic load modeling to the optimal scheduling of multi-building systems in the energy market is proposed. Sources of potential load uncertainty are introduced in the proposed energy management problem formulation in order to investigate the impact on the resulting load schedule.

Near-chip compliant layer for reducing perimeter stress during assembly process

DOEpatents

Schultz, Mark D.; Takken, Todd E.; Tian, Shurong; Yao, Yuan

2018-03-20

A heat source (single semiconductor chip or group of closely spaced semiconductor chips of similar height) is provided on a first side of a substrate, which substrate has on said first side a support member comprising a compressible material. A heat removal component, oriented at an angle to said heat source, is brought into proximity of said heat source such that said heat removal component contacts said support member prior to contacting said heat source. Said heat removal component is assembled to said heat source such that said support member at least partially absorbs global inequality of force that would otherwise be applied to said heat source, absent said support member comprising said compressible material.

Near-chip compliant layer for reducing perimeter stress during assembly process

DOEpatents

Schultz, Mark D.; Takken, Todd E.; Tian, Shurong; Yao, Yuan

2017-02-14

A heat source (single semiconductor chip or group of closely spaced semiconductor chips of similar height) is provided on a first side of a substrate, which substrate has on said first side a support member comprising a compressible material. A heat removal component, oriented at an angle to said heat source, is brought into proximity of said heat source such that said heat removal component contacts said support member prior to contacting said heat source. Said heat removal component is assembled to said heat source such that said support member at least partially absorbs global inequality of force that would otherwise be applied to said heat source, absent said support member comprising said compressible material.

Inner shell radial pin geometry and mounting arrangement

DOEpatents

Leach, David; Bergendahl, Peter Allen

2002-01-01

Circumferentially spaced arrays of support pins are disposed through access openings in an outer turbine shell and have projections received in recesses in forward and aft sections of an inner turbine shell supported from the outer shell. The projections have arcuate sides in a circumferential direction affording line contacts with the side walls of the recesses and are spaced from end faces of the recesses, enabling radial and axial expansion and contraction of the inner shell relative to the outer shell. All loads are taken up in a tangential direction by the outer shell with the support pins taking no radial loadings.

B-52 Flight Mission Symbology on Side of Craft

NASA Technical Reports Server (NTRS)

1993-01-01

A view of some of the mission markings, painted on the side of NASA's B-52 mothership, that tell the story of its colorful history. Just as combat aircraft would paint a bomb on the side of an aircraft for each bombing mission completed, NASA crew members painted a silhouette on the side of the B-52's fuselage to commemorate each drop of an X-15, lifting body, remotely piloted research vehicle, X-38 crew return vehicle, or other experimental vehicle or parachute system. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported eight orbiter (space shuttle) drag chute tests in 1990. In addition, the B-52 served as the air launch platform for the first six Pegasus space boosters. During its many years of service, the B-52 has undergone several modifications. The first major modification was made by North American Aviation (now part of Boeing) in support of the X-15 program. This involved creating a launch-panel-operator station for monitoring the status of the test vehicle being carried, cutting a large notch in the right inboard wing flap to accommodate the vertical tail of the X-15 aircraft, and installing a wing pylon that enables the B-52 to carry research vehicles and test articles to be air-launched/dropped. Located on the right wing, between the inboard engine pylon and the fuselage, this wing pylon was subjected to extensive testing prior to its use. For each test vehicle the B-52 carried, minor changes were made to the launch-panel operator's station. Built originally by the Boeing Company, the NASA B-52 is powered by eight Pratt & Whitney J57-19 turbojet engines, each of which produce 12,000 pounds of thrust. The aircraft's normal launch speed has been Mach 0.8 (about 530 miles per hour) and its normal drop altitude has been 40,000 to 45,000 feet. It is 156 feet long and has a wing span of 185 feet. The heaviest load it has carried was the No. 2 X-15 aircraft at 53,100 pounds. Project manager for the aircraft is Roy Bryant.

Neglect dyslexia: a review of the neuropsychological literature.

PubMed

Vallar, Giuseppe; Burani, Cristina; Arduino, Lisa S

2010-10-01

Neglect dyslexia (ND) is reviewed, based on published single-patient and group studies. ND is frequently associated with right hemispheric damage and unilateral spatial neglect (USN), and typically involves the left side of the letter string. Left-brain-damaged patients showing ND, ipsilateral (left) or contralateral (right) to the side of the left-sided hemispheric lesion, have also been reported, as well as a few patients with bilateral damage, with more frequently left than right ND. As USN, ND is temporarily ameliorated by lateralized stimulations (vestibular caloric, visual prism adaptation). ND may occur independent of USN, suggesting the damage to specific visuospatial representational/attentional systems, supporting reading. ND errors comprise omission, substitution, and, less frequently, addition of letters on one side of the stimulus, resulting in words or nonwords, also with reference to the stimulus' linguistic features. Patients with ND may show preserved lexical-morphological effects and implicit processing, up to the semantic level, of the misread string. This preserved processing is a feature of ND, shared with the USN syndrome. The mechanisms modulating error type and lexical-morphological effects are partly independent of each other. Different levels of representation of the letter string may be affected, giving rise to egocentric, stimulus-centred, and word-centred patterns of impairment. The anatomical correlates of ND include the temporo-parieto-occipital regions.

The Human Dimension -- Habitability AustroMars 2006

NASA Astrophysics Data System (ADS)

Haeuplik, S.; Imhof, B.

2007-10-01

Whether a cellular phone, a laptop computer or a spacecraft there are always two sides to an interface: a system side and a human side, and thus two sets of goals must be defined. In spaceflight, these two set of goals are defined for the technical system and the human system within its full scope. The human dimension is vital for a human mission if the mission should be successful. As the technical system is, compared with the human system less complex. The, and the focus up to now has hence been on the technical system; more understanding has been created and more knowledge has been developed. For future long duration human missions to which we are looking ahead when planning for outposts on the Moon and Mars, the human system has to play an equal role. The environment for which space architects are planning demands an extremely economical use of time, material and resources for the astronauts on mission, as well as attempts a maximum integration of environmental conditions and user requirements in design decisions, but also the mutual influence between humans and their environment, between active and passive systems. Human needs are always the same regardless of whether we are on the planet or in outer space. And they are a very architectural topic. Architecture is the three-dimensional creation of a shelter for humans supporting their needs and expanding their culture. Factors such as habitability (which include but are not limited to colour, smell, surface material tactility, food and the human -- machine interface), socio-psychological factors (which include crew selection and training, heterogeneity versus homogeneity of the crew, coping with stress, group dynamics, cognitive strategies, cultural background of the crew and its implications), culture and thus the resulting proportion of inhabitable space and it's functionality are a few topics of the complex theme 'Human Dimension'.

Cancer Treatment Side Effects: A Meta-analysis of the Relationship Between Response Expectancies and Experience.

PubMed

Devlin, Elise J; Denson, Linley A; Whitford, Hayley S

2017-08-01

Although previous research has, overall, suggested a moderate relationship between response expectancies (REs) and cancer treatment-related side effects, empirical results have been mixed. We aimed to further explore these relationships, hypothesizing that REs would predict subsequent toxicities with the inclusion of more recent studies, across a broader range of side effects, while incorporating the impact of potential moderators including patients' experience with treatment and measurement methods. We further investigated the impact of REs across individual toxicities. A systematic search and analysis were conducted across four databases (PsychInfo, PubMed, CINAHL, and Embase) and reference lists, from 1985 to February 2016. This provided 27 eligible studies with 4474 participants, through which the main analysis, moderator analyses, and individual side-effect analyses were explored. REs were moderately related to side effects overall (r = 0.26), and effect sizes were significantly influenced by sample diagnostic homogeneity, whereas differences between type and timing of measurement showed trends. Of the 16 toxicities examined, 15 demonstrated significant relationships between REs and side-effect experience, with hair loss (r = 0.48) the strongest. No clear difference emerged between objective and subjective side effects; however, significant differences across individual toxicities were revealed. Findings support a relationship between REs and a wide range of subsequent side effects, yet differences between individual RE-toxicity associations emerged. These findings provide direction for the measurement of side effects and REs and support REs as potential targets for intervention during the informed consent process. Copyright © 2017 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

26. VIEW OF PIN CONNECTION AT L2, SIDE VIEW, AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

26. VIEW OF PIN CONNECTION AT L2, SIDE VIEW, AND FLOOR BEAN SUPPORT, EAST TRUSS, SPAN 1, LOOKING NORTH - Emlenton Bridge, Spanning Allegheny River, Travel Route 38 (Legislative Route 75), Emlenton, Venango County, PA

1. OBLIQUE VIEW, NORTH AND EAST SIDES. VIEW SHOWS POSITION ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. OBLIQUE VIEW, NORTH AND EAST SIDES. VIEW SHOWS POSITION OF BUILDING UNDER LEG OF TOWER 33. - Chollas Heights Naval Radio Transmitting Facility, PERS Support Storage Building, 6410 Zero Road, San Diego, San Diego County, CA

Sales skills for health-care professionals: the emotional side of sales.

PubMed

Nigon, D L

2001-01-01

Health-care sales continues to be an area of opportunity for many laboratory professionals. For those who possess the necessary skills and the desire to enthusiastically embrace the unique challenges of a sales career, a new CLMA publication by CLMR contributor Donna L. Nigon, MT(ASCP), titled Sales Skills for Health-Care Professionals, will provide the knowledge of sales structure and techniques needed to succeed. This Sales Skills excerpt, "The Emotional Side of Sales," describes many of the emotional aspects of sales and selling, including how to handle the transition from a technical or medical role to that of sales representative, relationship building, maintaining personal and professional support systems, dealing with rejection, avoiding burnout, time management, and customer concerns. For more information about this book, please see the order form that accompanies this excerpt, or visit www.clma.org.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hajian, Hodjat, E-mail: hodjat.hajian@bilkent.edu.tr; Ozbay, Ekmel; Department of Physics, Bilkent University, 06800 Ankara

Certain types of photonic crystals with Dirac cones at the Γ point of their band structure have a zero effective index of refraction at Dirac cone frequency. Here, by an appropriate design of the photonic structure, we obtain a strong coupling between modes around the Dirac cone frequency of an all-dielectric zero-index photonic crystal and the guided ones supported by a photonic crystal waveguide. Consequently, we experimentally demonstrate that the presence of the zero-index photonic crystal at the inner side of the photonic crystal waveguide leads to an enhancement in the transmission of some of the guided waves passing throughmore » this hybrid system. Moreover, those electromagnetic waves extracted from the structure with enhanced transmission exhibit high directional beaming due to the presence of the zero-index photonic crystal at the outer side of the photonic crystal waveguide.« less

[Supportive care during chemotherapy for lung cancer in daily practice].

PubMed

Müller, Veronika; Tamási, Lilla; Gálffy, Gabriella; Losonczy, György

2012-09-01

Active oncotherapy, combination chemotherapy of lung cancer is accompanied with many side effects which may impair patients' quality of life and compromise the effectiveness of chemotherapy. Most side effects of chemotherapy are preventable or treatable with optimal supportive care which enhances success in patient care and treatment. The aim of this review is to summarize the most important conditions that may be associated with combined chemotherapy of lung cancer from the practical point of view.

Hot gas filter and system assembly

DOEpatents

Lippert, Thomas Edwin; Palmer, Kathryn Miles; Bruck, Gerald Joseph; Alvin, Mary Anne; Smeltzer, Eugene E.; Bachovchin, Dennis Michael

1999-01-01

A filter element for separating fine dirty particles from a hot gas. The filter element comprises a first porous wall and a second porous wall. Each porous wall has an outer surface and an inner surface. The first and second porous walls being coupled together thereby forming a substantially closed figure and open at one end. The open end is formed to be coupled to a hot gas clean up system support structure. The first and second porous walls define a channel beginning at the open end and terminate at the closed end through which a filtered clean gas can flow through and out into the clean gas side of a hot gas clean up system.

Hot gas filter and system assembly

DOEpatents

Lippert, T.E.; Palmer, K.M.; Bruck, G.J.; Alvin, M.A.; Smeltzer, E.E.; Bachovchin, D.M.

1999-08-31

A filter element is described for separating fine dirty particles from a hot gas. The filter element comprises a first porous wall and a second porous wall. Each porous wall has an outer surface and an inner surface. The first and second porous walls being coupled together thereby forming a substantially closed figure and open at one end. The open end is formed to be coupled to a hot gas clean up system support structure. The first and second porous walls define a channel beginning at the open end and terminate at the closed end through which a filtered clean gas can flow through and out into the clean gas side of a hot gas clean up system. 8 figs.

NASA DOEPOD NDE Capabilities Data Book

NASA Technical Reports Server (NTRS)

Generazio, Edward R.

2015-01-01

This data book contains the Directed Design of Experiments for Validating Probability of Detection (POD) Capability of NDE Systems (DOEPOD) analyses of the nondestructive inspection data presented in the NTIAC, Nondestructive Evaluation (NDE) Capabilities Data Book. DOEPOD is designed as a decision support system to validate inspection system, personnel, and protocol demonstrating 0.90 POD with 95% confidence at critical flaw sizes, a90/95. Although 0.90 POD with 95% confidence at critical flaw sizes is often stated as an inspection requirement in inspection documents, including NASA Standards, NASA critical aerospace applications have historically only accepted 0.978 POD or better with a 95% one-sided lower confidence bound exceeding 0.90 at critical flaw sizes, a90/95.

Evaluation of Acceptance of Nursing Information System in a German and American Hospital.

PubMed

Vollmer, Anne-Maria; Prokosch, Hans-Ulrich; Evans, Scott; Kuttler, Kathryn

2016-01-01

Nursing Information Systems (NIS) are not well-adopted and accepted in Germany. The evaluation of a NIS deployment in a German University Hospital supports this assumption. A second side study in the US should point out the differences regarding the technical and organizational differences. We use a questionnaire including standardized instruments like the Unified Theory of Acceptance (UTAUT). Results indicated that nurses in Germany compared to in the US do not use nursing process documentation to the same extent. The main reasons behind the low usage in comparison with the US are deficits in ease-of-use, system performance and the high expenditure of time and paper work for charting nursing plans.

Analysis of Risk Compensation Behavior on Night Vision Enhancement System

NASA Astrophysics Data System (ADS)

Hiraoka, Toshihiro; Masui, Junya; Nishikawa, Seimei

Advanced driver assistance systems (ADAS) such as a forward obstacle collision warning system (FOCWS) and a night vision enhancement system (NVES) aim to decrease driver's mental workload and enhance vehicle safety by provision of useful information to support driver's perception process and judgment process. On the other hand, the risk homeostasis theory (RHT) cautions that an enhanced safety and a reduced risk would cause a risk compensation behavior such as increasing the vehicle velocity. Therefore, the present paper performed the driving simulator experiments to discuss dependence on the NVES and emergence of the risk compensation behavior. Moreover, we verified the side-effects of spontaneous behavioral adaptation derived from the presentation of the fuel-consumption meter on the risk compensation behavior.

Lightweight Radiator System for a Spacecraft

NASA Technical Reports Server (NTRS)

Copeland, Robert J.; Mason, Georgia; Weislogel, Mark M.

2005-01-01

Three documents describe various aspects of a proposed lightweight, deployable radiator system for dissipating excess heat from the life-support system of a habitable spacecraft. The first document focuses on a radiator tube that would include a thin metal liner surrounded and supported by a thicker carbon-fiber-reinforced composite tubular structure that, in turn, would be formed as part of a unitary composite radiator-fin structure consisting mostly of a sheet of reticulated vitreous carbon laminated between carbon-fiber-reinforced face sheets. The thermal and mechanical properties, including the anisotropies, of the component materials are taken into account in the design. The second document describes thermo-structural bumpers, in the form of exterior multiple-ply carbon-fiber sheets enclosing hollows on opposite sides of a radiator fin, which would protect the radiator tube against impinging micrometeors and orbital debris. The third document describes a radiator system that would include multiple panels containing the aforementioned components, among others. The system would also include mechanisms for deploying the panels from compact stowage. Deployment would not involve breaking and remaking of fluid connections to the radiator panels.

Spacecube V2.0 Micro Single Board Computer

NASA Technical Reports Server (NTRS)

Petrick, David J. (Inventor); Geist, Alessandro (Inventor); Lin, Michael R. (Inventor); Crum, Gary R. (Inventor)

2017-01-01

A single board computer system radiation hardened for space flight includes a printed circuit board having a top side and bottom side; a reconfigurable field programmable gate array (FPGA) processor device disposed on the top side; a connector disposed on the top side; a plurality of peripheral components mounted on the bottom side; and wherein a size of the single board computer system is not greater than approximately 7 cm.times.7 cm.

Circulatory support for OPCAB procedures.

PubMed

Mueller, Xavier M; von Segesser, Ludwig K

2002-07-01

During off-pump coronary artery bypass grafting (OPCAB) which allows complete revascularization through a median sternotomy, revascularization of the lateral and posterior walls requires the verticalization of the heart, which may cause haemodynamic disturbance. This concern has stimulated the development of circulatory support with mini-pumps. Initially, these pumps were designed for the right side of the heart, which was found to be the main contributor to haemodynamic instability under experimental conditions. The three types of mini-pumps that have been developed so far - two for the right side of the heart and one for both sides - are reviewed as well as a new concept of integrated cardiopulmonary bypass (CPB) circuit with reduced surface and priming volume. However, with increasing experience and improved methods of exposition, OPCAB has become a procedure that can be performed without support in the majority of the cases. Nevertheless, the concept of miniaturization and the possibility to insert these devices through a peripheral access has opened the way to new indications, mainly short-term circulatory support for acute heart failure. This development is welcome in a field where available devices are invasive and plagued with a heavy morbidity.

Method and system for powering and cooling semiconductor lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Telford, Steven J; Ladran, Anthony S

A semiconductor laser system includes a diode laser tile. The diode laser tile includes a mounting fixture having a first side and a second side opposing the first side and an array of semiconductor laser pumps coupled to the first side of the mounting fixture. The semiconductor laser system also includes an electrical pulse generator thermally coupled to the diode bar and a cooling member thermally coupled to the diode bar and the electrical pulse generator.

Side-by-side comparisons of evacuated compound parabolic concentrator and flat plate solar collector systems at temperatures of 90 to 100C

NASA Astrophysics Data System (ADS)

Allen, J. W.; Schertz, W. W.; Wantroba, A. S.

1987-03-01

This collector system study is an extension of a previous system study in which Argonne National Laboratory (ANL) compared the performance of three solar energy systems operated side by side for over a year. In the present system study, four solar energy systems were operated side by side for part of a year. Two of the collector systems used commercially available compound parabolic concentrator (CPC) collectors, one used a commercially available flat plate collector, and one used an experimental CPC collector built by The University of Chicago. The collectors were mounted in fixed positions; they did not track the Sun, and their tilt angles were not seasonally adjusted. All of the collector arrays faced south and were tilted at 42 deg with respect to the horizon (to match the 42 deg N latitude at ANL). All four collector systems started each day with their storage temperatures at 90 C. During the day, each system was operated by its own solar controller. At the end of the day, the tanks were mixed and the temperature changes in the tanks were measured. The change in storage energy was calculated from the temperature change, the heat capacity of the storage system, and the pump energy.

An in vitro investigation into retention strength and fatigue resistance of various designs of tooth/implant supported overdentures.

PubMed

Fatalla, Abdalbseet A; Song, Ke; Du, Tianfeng; Cao, Yingguang

2012-02-01

Previously, the choice of prosthetic implant-retained overdentures has depended on data from previous studies about the retention-fatigue strength of the attachment system selected. Little or no data have been available on the correlation between the attachment system selected and the overdenture support configuration. The purpose of the present study was to evaluate the retention force and fatigue resistance of three attachment systems and four support designs of overdenture prosthesis. Four lower edentulous acrylic models were prepared and eight combinations of attachments groups were investigated in the study. These included: O-Rings with mini-dental implants (MDIs), Dalbo elliptic with Dalbo Rotex and fabricated flexible acrylic attachments with both MDI and Dalbo Rotex. The study was divided into four test groups: groups A and B, controls, and groups C and D, experimental groups. Control group A contained three overdenture supports: two free standing MDIs in the canine region and at the midline, and one simulated tooth root with Dalbo Rotex screwed in. Control group B contained four overdenture support foundations: two free standing MDIs in the right canine region and the first premolar region, and two simulated tooth roots with Dalbo Rotex screwed in at the same MDI position, but on the left side of the model. Experimental group C contained three overdenture support foundations: two free standing MDIs in the canine region and at the midline, and one simulated tooth root with MDI screwed in. Experimental group D contained four overdenture support foundations: two free standing MDIs in the right canine region and the first premolar region, and two simulated tooth roots with MDIs screwed in at the same MDI position, but on the left side of the model. Each group was further divided into two subgroups according to attachment type used. Five samples were prepared for each group. Retention force (N) values were recorded initially (0 cycles) and after 360, 720, 1440 and 2880 insertion and removal cycles. During the tensile test a cross-head speed of 10 mm/min was applied. Values of absolute force (AF) and relative force (RF) were statistically analyzed by two-way ANOVA and multiple comparison Tukey's tests between groups and cycles periods. The results of fatigue tests showed a 50% reduction in retention force in the subgroups with flexible attachments. A triangular design of overdenture support foundations with O-Ring attachments revealed the lowest value of AF and a relatively high reduction in RF. The four overdenture support designs with flexible acrylic attachments improved the retention force and reduced the fatigue retention. Furthermore, the results of the investigation demonstrate that flexible acrylic attachments for both teeth and implant-supported overdentures offer a wide range of retention forces.

STAR: an integrated solution to management and visualization of sequencing data

PubMed Central

Wang, Tao; Liu, Jie; Shen, Li; Tonti-Filippini, Julian; Zhu, Yun; Jia, Haiyang; Lister, Ryan; Whitaker, John W.; Ecker, Joseph R.; Millar, A. Harvey; Ren, Bing; Wang, Wei

2013-01-01

Motivation: Easily visualization of complex data features is a necessary step to conduct studies on next-generation sequencing (NGS) data. We developed STAR, an integrated web application that enables online management, visualization and track-based analysis of NGS data. Results: STAR is a multilayer web service system. On the client side, STAR leverages JavaScript, HTML5 Canvas and asynchronous communications to deliver a smoothly scrolling desktop-like graphical user interface with a suite of in-browser analysis tools that range from providing simple track configuration controls to sophisticated feature detection within datasets. On the server side, STAR supports private session state retention via an account management system and provides data management modules that enable collection, visualization and analysis of third-party sequencing data from the public domain with over thousands of tracks hosted to date. Overall, STAR represents a next-generation data exploration solution to match the requirements of NGS data, enabling both intuitive visualization and dynamic analysis of data. Availability and implementation: STAR browser system is freely available on the web at http://wanglab.ucsd.edu/star/browser and https://github.com/angell1117/STAR-genome-browser. Contact: wei-wang@ucsd.edu PMID:24078702

Lsiviewer 2.0 - a Client-Oriented Online Visualization Tool for Geospatial Vector Data

NASA Astrophysics Data System (ADS)

Manikanta, K.; Rajan, K. S.

2017-09-01

Geospatial data visualization systems have been predominantly through applications that are installed and run in a desktop environment. Over the last decade, with the advent of web technologies and its adoption by Geospatial community, the server-client model for data handling, data rendering and visualization respectively has been the most prevalent approach in Web-GIS. While the client devices have become functionally more powerful over the recent years, the above model has largely ignored it and is still in a mode of serverdominant computing paradigm. In this paper, an attempt has been made to develop and demonstrate LSIViewer - a simple, easy-to-use and robust online geospatial data visualisation system for the user's own data that harness the client's capabilities for data rendering and user-interactive styling, with a reduced load on the server. The developed system can support multiple geospatial vector formats and can be integrated with other web-based systems like WMS, WFS, etc. The technology stack used to build this system is Node.js on the server side and HTML5 Canvas and JavaScript on the client side. Various tests run on a range of vector datasets, upto 35 MB, showed that the time taken to render the vector data using LSIViewer is comparable to a desktop GIS application, QGIS, over an identical system.

Translatory shock absorber for attitude sensors

NASA Technical Reports Server (NTRS)

Vonpragenau, G. L.; Morgan, I. T., Jr.; Kirby, C. A. (Inventor)

1976-01-01

A translatory shock absorber is provided for mounting an attitude sensor thereon for isolating a sensor from translatory vibrations. The translatory shock absorber includes a hollow block structure formed as one piece to form a parallelogram. The absorber block structure includes a movable top plate for supporting the attitude sensor and a fixed base plate with opposed side plates interposed between. At the junctions of the side plates, and the base and top plates, there are provided grooves which act as flexible hinges for attenuating translatory vibrations. A damping material is supported on a pedestal which is carried on the base plate between the side plates thereof. The top of the damping material rests against the bottom surface of the top plate for eliminating the resonant peaks of vibration.

Monolayer adsorption of noble gases on graphene

NASA Astrophysics Data System (ADS)

Maiga, Sidi M.; Gatica, Silvina M.

2018-02-01

We report our results of simulations of the adsorption of noble gases (Kr, Ar, Xe) on graphene. For Kr, we consider two configurations: supported and free-standing graphene, where atoms are adsorbed only on one or two sides of the graphene. For Ar and Xe, we studied only the case of supported graphene. For the single-side adsorption, we calculated the two-dimensional gas-liquid critical temperature for each adsorbate. We determined the different phases of the monolayers and constructed the phase diagrams. We found two-dimensional incommensurate solid phases for krypton, argon and xenon, and a two-dimensional commensurate solid phase for krypton. For double side adsorption of Kr, we do not see evidence of an ordering transition driven by the interlayer forces.

Ice flood velocity calculating approach based on single view metrology

NASA Astrophysics Data System (ADS)

Wu, X.; Xu, L.

2017-02-01

Yellow River is the river in which the ice flood occurs most frequently in China, hence, the Ice flood forecasting has great significance for the river flood prevention work. In various ice flood forecast models, the flow velocity is one of the most important parameters. In spite of the great significance of the flow velocity, its acquisition heavily relies on manual observation or deriving from empirical formula. In recent years, with the high development of video surveillance technology and wireless transmission network, the Yellow River Conservancy Commission set up the ice situation monitoring system, in which live videos can be transmitted to the monitoring center through 3G mobile networks. In this paper, an approach to get the ice velocity based on single view metrology and motion tracking technique using monitoring videos as input data is proposed. First of all, River way can be approximated as a plane. On this condition, we analyze the geometry relevance between the object side and the image side. Besides, we present the principle to measure length in object side from image. Secondly, we use LK optical flow which support pyramid data to track the ice in motion. Combining the result of camera calibration and single view metrology, we propose a flow to calculate the real velocity of ice flood. At last we realize a prototype system by programming and use it to test the reliability and rationality of the whole solution.

Antimisting Fuel (AMK) Flight Degrader Development and Aircraft Fuel System Investigation

DTIC Science & Technology

1987-02-01

Summary of Test Results 134 CV880 Support of the CID Mission 135 Comparison of the Pump/Degrader and Needle- Valve Degrader 146 Operation on Freshly Blended...Drain Valve 53 AM 33. View of Right Side of Number 3 Engine 54 34. Redundant Shutoff Valve 55 35. Bottom View of Number 3 Engine 55 36. Onboard...Supply and Regulation/Shutoff Valves 78 44. ATMP8O-1 Pump/Degrader Test Module 79 45. Fuel Flow Circuits 80 vii La LIST OF ILLUSTRATIONS (Continued

Agent-Based Simulation to Support the Effectiveness, Procurement, and Employment of Non-Lethal Weapon Systems

DTIC Science & Technology

2017-06-01

cases have the most significant impact on reducing the number of lethal shots fired in the simulation. Table 10 shows the reduction in the average...Figure ES-2 was developed to show the results of the focused study on maximum effective range. After analyzing the results of the 1,700 simulated...toward other agents based on whose side they are on at that time. This attribute is critical to this study as the sidedness of the local population is

International Data Archive

DTIC Science & Technology

1971-01-01

ARBOR, MICHIGAN A8104 © y Technical Progress Report // 4 1 January through 30 June 1971 ooO\\ Prepared in connection with research supported by...34? SSr^ ^ IRA ^ WEIS data from Janu- y . 1^66 though The data and source of each item is included in the analytic deck Also included is a descriptive...WEIGHTED, WEIGHTED, CHINESE: EXrrtA-SYSTEM ALL SIDES IN QUARREL BXTHA-nEGIONAL EXTRA-SYSTEH EXTRAS EG 10NAL (!1 EMB ER) E X T H A. J Y S T

Impact of Public Perception on US National Policy: A Study of Media Influence in Military and Government Decision Making

DTIC Science & Technology

2002-09-01

In actuality the system definitions and boundaries are being reinforced by the limits placed on the debate. There is no formal censorship in the US...enemy and reinforces it with rhetoric in support of their own side, leading to a further problem with double standards and hypocrisy than already...the Media, Public Policy, and Humanitarian Crises. Washington DC: The Brookings Institution, 1996, p. 136. 28 Ibid, p. 138. 30 demand immediate

Containers for use in a self supporting assembly

DOEpatents

Gillespie, Peter J.

1982-07-13

This invention is directed to a container having side walls and end walls forming a body having a generally rectangular cross-section. Means for restraining lateral and rotational movement of the container relative to an adjacent container while allowing relatively unhindered movement perpendicular to the side walls is also included. The lateral and rotational movement is restrained in a plane parallel to the side walls. The means include a projection connected to at least one of the side walls and extending outwardly therefrom to engage the adjacent container. Also part of this invention is an assembly of containers which includes a plurality of the above described containers arranged side by side with the end walls generally coplanar and the side walls generally parallel. Means for restraining movement perpendicular to the side walls of the plurality of containers is also included. Each of the containers may house a plurality of battery electrodes.

Failure Mechanisms of Hollow Fiber Supported Ionic Liquid Membranes

PubMed Central

Zeh, Matthew; Wickramanayake, Shan; Hopkinson, David

2016-01-01

Hollow fiber supported ionic liquid membranes (SILMs) were tested using the bubble point method to investigate potential failure modes, including the maximum transmembrane pressure before loss of the ionic liquid from the support. Porous hollow fiber supports were fabricated with different pore morphologies using Matrimid® and Torlon® as the polymeric material and 1-hexyl-3-methylimidalzolium bis(trifluoromethylsulfonyl)imide ([C6mim][Tf2N]) as the ionic liquid (IL) component. Hollow fiber SILMs were tested for their maximum pressure before failure, with pressure applied either from the bore side or shell side. It was found that the membranes exhibited one or more of three different modes of failure when pressurized: liquid loss (occurring at the bubble point), rupture, and collapse. PMID:27023620

Orbiter fire rescue and crew escape training for EVA crew systems support

NASA Image and Video Library

1993-01-28

Photos of orbiter fire rescue and crew escape training for extravehicular activity (EVA) crew systems support conducted in Bldg 9A Crew Compartment Trainer (CCT) and Fuel Fuselage Trainer (FFT) include views of CCT interior of middeck starboard fuselage showing middeck forward (MF) locker and COAS assembly filter, artiflex film and camcorder bag (26834); launch/entry suit (LES) helmet assembly, neckring and helmet hold-down assembly (26835-26836); middeck aft (MA) lockers (26837); area of middeck airlock and crew escape pole (26838); connectors of crew escape pole in the middeck (268390); three test subjects in LES in the flight deck (26840); emergency side hatch slide before inflated stowage (26841); area of below adjacent to floor panel MD23R (26842); a test subject in LES in the flight deck (26843); control board and also showing sign of "orbital maneuvering system (OMS) secure and OMS TK" (26844); test subject in the flight deck also showing chart of "ascent/abort summary" (26845).

Operationalizing Surveillance of Chronic Disease Self-Management and Self-Management Support

PubMed Central

Sacks, Jeffrey J.; Terrillion, Albert J.; Colligan, Erin M.

2018-01-01

Sixty percent of US adults have at least one chronic condition, and more than 40% have multiple conditions. Self-management (SM) by the individual, along with self-management support (SMS) by others, are nonpharmacological interventions with few side effects that are critical to optimal chronic disease control. Ruiz and colleagues laid the conceptual groundwork for surveillance of SM/SMS at 5 socio-ecological levels (individual, health system, community, policy, and media). We extend that work by proposing operationalized indicators at each socio-ecologic level and suggest that the indicators be embedded in existing surveillance systems at national, state, and local levels. Without a robust measurement system at the population level, we will not know how far we have to go or how far we have come in making SM and SMS a reality. The data can also be used to facilitate planning and service delivery strategies, monitor temporal changes, and stimulate SM/SMS–related research. PMID:29625631

Single Sided Messaging v. 0.6.6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Curry, Matthew Leon; Farmer, Matthew Shane; Hassani, Amin

Single-Sided Messaging (SSM) is a portable, multitransport networking library that enables applications to leverage potential one-sided capabilities of underlying network transports. It also provides desirable semantics that services for highperformance, massively parallel computers can leverage, such as an explicit cancel operation for pending transmissions, as well as enhanced matching semantics favoring large numbers of buffers attached to a single match entry. This release supports TCP/IP, shared memory, and Infiniband.

Mechanical support of a ceramic gas turbine vane ring

DOEpatents

Shi, Jun; Green, Kevin E.; Mosher, Daniel A.; Holowczak, John E.; Reinhardt, Gregory E.

2010-07-27

An assembly for mounting a ceramic turbine vane ring onto a turbine support casing comprises a first metal clamping ring and a second metal clamping ring. The first metal clamping ring is configured to engage with a first side of a tab member of the ceramic turbine vane ring. The second metal clamping ring is configured to engage with a second side of the tab member such that the tab member is disposed between the first and second metal clamping rings.

10. VIEW TO NORTHEAST FROM WITHIN SOUTHWEST BAY, LOOKING THROUGH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. VIEW TO NORTHEAST FROM WITHIN SOUTHWEST BAY, LOOKING THROUGH CENTER BAY AND INTO NORTHEAST BAY. NOTE TRAVELING BRIDGE CRANE OVERHEAD AND SWINGING BOOM CRANES ATTACHED TO COLUMNS ON RIGHT AND LEFT. NOTE ALSO THE DIFFERENCE IN TRUSSES SUPPORTING CRANEWAY TRACKS FOR SIDE BAYS AND CENTER BAY. TRUSSES SUPPORTING CRANEWAY TRACKS IN SIDE BAYS (CENTER FOREGROUND AND FAR BACKGROUND) ARE HOWE TRUSSES WITH WOOD DIAGONALS AND STEEL VERTICALS. TRUSSES SUPPORTING CRANEWAY TRACKS IN CENTER BAY (MID BACKGROUND) ARE PRATT TRUSSES WITH WOOD VERTICALS AND DIAGONALS. - Rosie the Riveter National Historical Park, Auxiliary Plate Shop, 912 Harbour Way, Richmond, Contra Costa County, CA

Effect of spray angle and spray volume on deposition of a medium droplet spray with air support in ivy pot plants.

PubMed

Foqué, Dieter; Pieters, Jan G; Nuyttens, David

2014-03-01

Spray boom systems, an alternative to the predominantly-used spray guns, have the potential to considerably improve crop protection management in glasshouses. Based on earlier experiments, the further optimization of the deposits of a medium spray quality extended range flat fan nozzle type using easy adjustable spray boom settings was examined. Using mineral chelate tracers and water sensitive papers, the spray results were monitored at three plant levels, on the upper side and the underside of the leaves, and on some off-target collectors. In addition, the deposition datasets of all tree experiments were compared. The data showed that the most efficient spray distribution with the medium spray quality flat fan nozzles was found with a 30° forward angled spray combined with air support and an application rate of 1000 L ha(-1) . This technique resulted in a more uniform deposition in the dense canopy and increased spray deposition on the lower side of the leaves compared with the a standard spray boom application. Applying 1000 L ha(-1) in two subsequent runs instead of one did not seem to show any added value. Spray deposition can be improved hugely simply by changing some spray boom settings like nozzle type, angling the spray, using air support and adjusting the spray volume to the crop. © 2013 Society of Chemical Industry.

Similarity-based prediction for Anatomical Therapeutic Chemical classification of drugs by integrating multiple data sources.

PubMed

Liu, Zhongyang; Guo, Feifei; Gu, Jiangyong; Wang, Yong; Li, Yang; Wang, Dan; Lu, Liang; Li, Dong; He, Fuchu

2015-06-01

Anatomical Therapeutic Chemical (ATC) classification system, widely applied in almost all drug utilization studies, is currently the most widely recognized classification system for drugs. Currently, new drug entries are added into the system only on users' requests, which leads to seriously incomplete drug coverage of the system, and bioinformatics prediction is helpful during this process. Here we propose a novel prediction model of drug-ATC code associations, using logistic regression to integrate multiple heterogeneous data sources including chemical structures, target proteins, gene expression, side-effects and chemical-chemical associations. The model obtains good performance for the prediction not only on ATC codes of unclassified drugs but also on new ATC codes of classified drugs assessed by cross-validation and independent test sets, and its efficacy exceeds previous methods. Further to facilitate the use, the model is developed into a user-friendly web service SPACE ( S: imilarity-based P: redictor of A: TC C: od E: ), which for each submitted compound, will give candidate ATC codes (ranked according to the decreasing probability_score predicted by the model) together with corresponding supporting evidence. This work not only contributes to knowing drugs' therapeutic, pharmacological and chemical properties, but also provides clues for drug repositioning and side-effect discovery. In addition, the construction of the prediction model also provides a general framework for similarity-based data integration which is suitable for other drug-related studies such as target, side-effect prediction etc. The web service SPACE is available at http://www.bprc.ac.cn/space. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Health care reform and care at the behavioral health--primary care interface.

PubMed

Druss, Benjamin G; Mauer, Barbara J

2010-11-01

The historic passage of the Patient Protection and Affordable Care Act in March 2010 offers the potential to address long-standing deficits in quality and integration of services at the interface between behavioral health and primary care. Many of the efforts to reform the care delivery system will come in the form of demonstration projects, which, if successful, will become models for the broader health system. This article reviews two of the programs that might have a particular impact on care on the two sides of that interface: Medicaid and Medicare patient-centered medical home demonstration projects and expansion of a Substance Abuse and Mental Health Services Administration program that colocates primary care services in community mental health settings. The authors provide an overview of key supporting factors, including new financing mechanisms, quality assessment metrics, information technology infrastructure, and technical support, that will be important for ensuring that initiatives achieve their potential for improving care.

Hatch cover

NASA Technical Reports Server (NTRS)

Allton, Charles S. (Inventor); Okane, James H. (Inventor)

1989-01-01

This invention relates to a hatch and more particularly to a hatch for a space vehicle where the hatch has a low volume sweep and can be easily manipulated from either side of the hatch. The hatch system includes an elliptical opening in a bulkhead and an elliptical hatch member. The hatch cover system includes an elliptical port opening in a housing and an elliptical cover member supported centrally by a rotational bearing for rotation about a rotational axis normal to the cover member and by pivot pins in a gimbal member for pivotal movement about axes perpendicular to the rotational axis. Arm members support the gimbal member pivotally by pivot members so that upon rotation and manipulation the cover member can be articulatedly moved from a closed position to the port opening to an out of the way position with a minimum of volume sweep by the cover member.

Highly damped kinematic coupling for precision instruments

DOEpatents

Hale, Layton C.; Jensen, Steven A.

2001-01-01

A highly damped kinematic coupling for precision instruments. The kinematic coupling provides support while causing essentially no influence to its nature shape, with such influences coming, for example, from manufacturing tolerances, temperature changes, or ground motion. The coupling uses three ball-cone constraints, each combined with a released flexural degree of freedom. This arrangement enables a gain of higher load capacity and stiffness, but can also significantly reduce the friction level in proportion to the ball radius divided by the distance between the ball and the hinge axis. The blade flexures reduces somewhat the stiffness of the coupling and provides an ideal location to apply constrained-layer damping which is accomplished by attaching a viscoelastic layer and a constraining layer on opposite sides of each of the blade flexures. The three identical ball-cone flexures provide a damped coupling mechanism to kinematically support the projection optics system of the extreme ultraviolet lithography (EUVL) system, or other load-sensitive apparatus.

Exploring Tradeoffs in Demand-side and Supply-side Management of Urban Water Resources using Agent-based Modeling and Evolutionary Computation

NASA Astrophysics Data System (ADS)

Kanta, L.; Berglund, E. Z.

2015-12-01

Urban water supply systems may be managed through supply-side and demand-side strategies, which focus on water source expansion and demand reductions, respectively. Supply-side strategies bear infrastructure and energy costs, while demand-side strategies bear costs of implementation and inconvenience to consumers. To evaluate the performance of demand-side strategies, the participation and water use adaptations of consumers should be simulated. In this study, a Complex Adaptive Systems (CAS) framework is developed to simulate consumer agents that change their consumption to affect the withdrawal from the water supply system, which, in turn influences operational policies and long-term resource planning. Agent-based models are encoded to represent consumers and a policy maker agent and are coupled with water resources system simulation models. The CAS framework is coupled with an evolutionary computation-based multi-objective methodology to explore tradeoffs in cost, inconvenience to consumers, and environmental impacts for both supply-side and demand-side strategies. Decisions are identified to specify storage levels in a reservoir that trigger (1) increases in the volume of water pumped through inter-basin transfers from an external reservoir and (2) drought stages, which restrict the volume of water that is allowed for residential outdoor uses. The proposed methodology is demonstrated for Arlington, Texas, water supply system to identify non-dominated strategies for an historic drought decade. Results demonstrate that pumping costs associated with maximizing environmental reliability exceed pumping costs associated with minimizing restrictions on consumer water use.

Development of Anode-Supported Single Cells and Small Stacks for Intermediate Temperature Sofc at Kepri

NASA Astrophysics Data System (ADS)

Yoo, Y.-S.; Park, J.-W.; Park, J.-K.; Lim, H.-C.; Oh, J.-M.; Bae, J.-M.

Recent results on intermediate temperature-operating solid oxide fuel cells (IT-SOFC) are mainly focused on getting the higher performance of single cell at lower operating temperature, especially using planar type. We have started a project to develop 1 kW-class SOFC system for Residential Power Generation(RPG) application. For a 1 kW-class SOFC stack that can be operated at intermediate temperatures, we have developed anode-supported, planar type SOFC to have advantages for commercialization of SOFCs considering mass production and using cost-effective interconnects such as ferritic stainless steels. At higher temperature, performance of SOFC can be increased due to higher electrochemical activity of electrodes and lower ohmic losses, but the surface of metallic interconnects at cathode side is rapidly oxidized into resistive oxide scale. For efficient operation of SOFC at reduced temperature at, firstly we have developed alternative cathode materials of LSCF instead of LSM to get higher performance of electrodes, and secondly introduced functional-layered structure at anode side. The I-V and AC impedance characteristics of improved single cells and small stacks were evaluated at intermediate temperatures (650°C and 750°C) using hydrogen gas as a fuel.

KSC-01pp1185

NASA Image and Video Library

2001-06-21

KENNEDY SPACE CENTER, Fla. -- Atop the mobile launcher platform, Space Shuttle Atlantis, with its orange external tank and white solid rocket boosters, sits on Launch Pad 39B after rollout from the Vehicle Assembly Building. Seen on either side of the orbiter’s tail are the tail service masts. They support the fluid, gas and electrical requirements of the orbiter’s liquid oxygen and liquid hydrogen aft umbilicals. The Shuttle is targeted for launch no earlier than July 12 on mission STS-104, the 10th flight to the International Space Station. The payload on the 11-day mission is the Joint Airlock Module, which will allow astronauts and cosmonauts in residence on the Station to perform future spacewalks without the presence of a Space Shuttle. The module, which comprises a crew lock and an equipment lock, will be connected to the starboard (right) side of Node 1 Unity. Atlantis will also carry oxygen and nitrogen storage tanks, vital to operation of the Joint Airlock, on a Spacelab Logistics Double Pallet in the payload bay. The tanks, to be installed on the perimeter of the Joint Module during the mission’s spacewalks, will support future spacewalk operations and experiments plus augment the resupply system for the Station’s Service Module

KSC-01pp1184

NASA Image and Video Library

2001-06-21

KENNEDY SPACE CENTER, Fla. -- Atop the mobile launcher platform, Space Shuttle Atlantis arrives on Launch Pad 39B after rollout from the Vehicle Assembly Building. Seen on either side of the orbiter’s tail are the tail service masts. They support the fluid, gas and electrical requirements of the orbiter’s liquid oxygen and liquid hydrogen aft umbilicals. The Shuttle is targeted for launch no earlier than July 12 on mission STS-104, the 10th flight to the International Space Station. The payload on the 11-day mission is the Joint Airlock Module, which will allow astronauts and cosmonauts in residence on the Station to perform future spacewalks without the presence of a Space Shuttle. The module, which comprises a crew lock and an equipment lock, will be connected to the starboard (right) side of Node 1 Unity. Atlantis will also carry oxygen and nitrogen storage tanks, vital to operation of the Joint Airlock, on a Spacelab Logistics Double Pallet in the payload bay. The tanks, to be installed on the perimeter of the Joint Module during the mission’s spacewalks, will support future spacewalk operations and experiments plus augment the resupply system for the Station’s Service Module

Space Shuttle Atlantis is on Launch Pad 39B

NASA Technical Reports Server (NTRS)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- Atop the mobile launcher platform, Space Shuttle Atlantis, with its orange external tank and white solid rocket boosters, sits on Launch Pad 39B after rollout from the Vehicle Assembly Building. Seen on either side of the orbiters tail are the tail service masts. They support the fluid, gas and electrical requirements of the orbiters liquid oxygen and liquid hydrogen aft umbilicals. The Shuttle is targeted for launch no earlier than July 12 on mission STS-104, the 10th flight to the International Space Station. The payload on the 11- day mission is the Joint Airlock Module, which will allow astronauts and cosmonauts in residence on the Station to perform future spacewalks without the presence of a Space Shuttle. The module, which comprises a crew lock and an equipment lock, will be connected to the starboard (right) side of Node 1 Unity. Atlantis will also carry oxygen and nitrogen storage tanks, vital to operation of the Joint Airlock, on a Spacelab Logistics Double Pallet in the payload bay. The tanks, to be installed on the perimeter of the Joint Module during the missions spacewalks, will support future spacewalk operations and experiments plus augment the resupply system for the Stations Service Module.

Space Shuttle Atlantis is on Launch Pad 39B

NASA Technical Reports Server (NTRS)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- Atop the mobile launcher platform, Space Shuttle Atlantis arrives on Launch Pad 39B after rollout from the Vehicle Assembly Building. Seen on either side of the orbiters tail are the tail service masts. They support the fluid, gas and electrical requirements of the orbiters liquid oxygen and liquid hydrogen aft umbilicals. The Shuttle is targeted for launch no earlier than July 12 on mission STS-104, the 10th flight to the International Space Station. The payload on the 11- day mission is the Joint Airlock Module, which will allow astronauts and cosmonauts in residence on the Station to perform future spacewalks without the presence of a Space Shuttle. The module, which comprises a crew lock and an equipment lock, will be connected to the starboard (right) side of Node 1 Unity. Atlantis will also carry oxygen and nitrogen storage tanks, vital to operation of the Joint Airlock, on a Spacelab Logistics Double Pallet in the payload bay. The tanks, to be installed on the perimeter of the Joint Module during the missions spacewalks, will support future spacewalk operations and experiments plus augment the resupply system for the Stations Service Module.

Pad 39B Flame Trench Brick Work

NASA Image and Video Library

2016-10-26

Progress continues on the new flame trench at Launch Pad 39B at NASA's Kennedy Space Center in Florida. Construction workers with J.P. Donovan of Rockledge, Florida, prepare new heat-resistant bricks for installation on the north side of the flame trench. The Pad B flame trench is being refurbished to support the launch of NASA’s Space Launch System rocket. The Ground Systems Development and Operations (GSDO) Program at Kennedy is helping transform the space center into a multi-user spaceport and prepare for Exploration Mission 1, deep space missions, and NASA's Journey to Mars. For more information about GSDO, visit: http://www.nasa.gov/groundsystems.

Pad 39B Flame Trench Brick Work

NASA Image and Video Library

2016-10-26

Progress continues on the new flame trench at Launch Pad 39B at NASA's Kennedy Space Center in Florida. Construction workers with J.P. Donovan of Rockledge, Florida, attach new heat-resistant bricks on the north side of the flame trench. The Pad B flame trench is being refurbished to support the launch of NASA’s Space Launch System rocket. The Ground Systems Development and Operations (GSDO) Program at Kennedy is helping transform the space center into a multi-user spaceport and prepare for Exploration Mission 1, deep space missions, and NASA's Journey to Mars. For more information about GSDO, visit: http://www.nasa.gov/groundsystems.

Pad 39B Flame Trench Brick Work

NASA Image and Video Library

2016-10-26

A construction worker with J.P. Donovan of Rockledge, Florida, checks to make sure new heat-resistant bricks attached to the north side of the flame trench are level at Launch Pad 39B at NASA’s Kennedy Space Center in Florida. The Pad B flame trench is being refurbished to support the launch of NASA’s Space Launch System rocket. The Ground Systems Development and Operations (GSDO) Program at Kennedy is helping transform the space center into a multi-user spaceport and prepare for Exploration Mission 1, deep space missions, and NASA's Journey to Mars. For more information about GSDO, visit: http://www.nasa.gov/groundsystems.

MS Peterson and MS Musgrave in payload bay (PLB) during EVA

NASA Technical Reports Server (NTRS)

1983-01-01

Extravehicular mobility unit (EMU) suited Mission Specialist (MS) Peterson, designated EV2, translates from forward payload bay (PLB) to aft bulkhead worksite along port side sill longeron using tether and slidewire system while MS Musgrave, designated EV1, floats on a tether in center of PLB. Inertial Upper Stage (IUS) Airborne Support Equipment (ASE) forward frame and aft frame tilt actuator (AFTA) table appear in front and behind Musgrave and vertical tail and Orbital Maneuvering System (OMS) pods appear in background highlighted against the cloudy surface of Earth. EMU mini workstation extravehicular activity (EVA) crewmember safety tether reel floats on Musgrave's waist tether.

A-1 Test Stand work

NASA Technical Reports Server (NTRS)

2010-01-01

Employees at NASA's John C. Stennis Space Center work to maneuver a structural steam beam into place on the A-1 Test Stand on Jan. 13. The beam was one of several needed to form the thrust takeout structure that will support a new thrust measurement system being installed on the stand for future rocket engine testing. Once lifted onto the stand, the beams had to be hoisted into place through the center of the test stand, with only two inches of clearance on each side. The new thrust measurement system represents a state-of-the-art upgrade from the equipment installed more than 40 years ago when the test stand was first constructed.

Reflective all-sky thermal infrared cloud imager

DOE Office of Scientific and Technical Information (OSTI.GOV)

Redman, Brian J.; Shaw, Joseph A.; Nugent, Paul W.

A reflective all-sky imaging system has been built using a long-wave infrared microbolometer camera and a reflective metal sphere. This compact system was developed for measuring spatial and temporal patterns of clouds and their optical depth in support of applications including Earth-space optical communications. The camera is mounted to the side of the reflective sphere to leave the zenith sky unobstructed. The resulting geometric distortion is removed through an angular map derived from a combination of checkerboard-target imaging, geometric ray tracing, and sun-location-based alignment. A tape of high-emissivity material on the side of the reflector acts as a reference thatmore » is used to estimate and remove thermal emission from the metal sphere. In conclusion, once a bias that is under continuing study was removed, sky radiance measurements from the all-sky imager in the 8-14 μm wavelength range agreed to within 0.91 W/(m 2 sr) of measurements from a previously calibrated, lens-based infrared cloud imager over its 110° field of view.« less

Reflective all-sky thermal infrared cloud imager

DOE PAGES

Redman, Brian J.; Shaw, Joseph A.; Nugent, Paul W.; ...

2018-04-17

A reflective all-sky imaging system has been built using a long-wave infrared microbolometer camera and a reflective metal sphere. This compact system was developed for measuring spatial and temporal patterns of clouds and their optical depth in support of applications including Earth-space optical communications. The camera is mounted to the side of the reflective sphere to leave the zenith sky unobstructed. The resulting geometric distortion is removed through an angular map derived from a combination of checkerboard-target imaging, geometric ray tracing, and sun-location-based alignment. A tape of high-emissivity material on the side of the reflector acts as a reference thatmore » is used to estimate and remove thermal emission from the metal sphere. In conclusion, once a bias that is under continuing study was removed, sky radiance measurements from the all-sky imager in the 8-14 μm wavelength range agreed to within 0.91 W/(m 2 sr) of measurements from a previously calibrated, lens-based infrared cloud imager over its 110° field of view.« less

System for loading slab-gel holders for electrophoresis separation

DOEpatents

Anderson, Norman G.; Anderson, Norman L.

1979-01-01

A slab-gel loading system includes a prismatic chamber for filling a plurality of slab-gel holders simultaneously. Each slab-gel holder comprises a pair of spaced apart plates defining an intermediate volume for gel containment. The holders are vertically positioned in the chamber with their major surfaces parallel to the chamber end walls. A liquid inlet is provided at the corner between the bottom and a side wall of the chamber for distributing a polymerizable monomer solution or a coagulable colloidal solution into each of the holders. The chamber is rotatably supported so that filling can begin with the corner having the liquid inlet directed downwardly such that the solution is gently funneled upwardly, without mixing, along the diverging side and bottom surfaces. As filling proceeds, the chamber is gradually rotated to position the bottom wall in a horizontal mode. The liquid filling means includes a plastic envelope with a septum dividing it into two compartments for intermixing two solutions of different density and thereby providing a liquid flow having a density gradient. The resulting gels have a density gradient between opposite edges for subsequent use in electrophoresis separations.

The Goddard High Resolution Spectrograph Scientific Support Contract

NASA Technical Reports Server (NTRS)

1997-01-01

In 1988, Computer Sciences Corporation (CSC) was selected as the Goddard High Resolution Spectrograph (GHRS) Scientific Support Contractor (SSC). This was to have been a few months before the launch of NASA's first Great Observatory, the Hubble Space Telescope (HST). As one of five scientific instruments on HST, the GHRS was designed to obtain spectra in the 1050-3300 A ultraviolet wavelength region with a resolving power, lambda/Delta(lambda) , of up to 100,000 and relative photometric accuracy to 1%. It was built by Ball AeroSpace Systems Group under the guidance of the GHRS Investigation Definition Team (IDT), comprised of 16 scientists from the US and Canada. After launch, the IDT was to perform the initial instrument calibration and execute a broad scientific program during a five-year Guaranteed Time Observation (GTO) period. After a year's delay, the launch of HST occurred in April 1990, and CSC participated in the in-orbit calibration and first four years of GTO observations with the IDT. The HST primary mirror suffered from spherical aberration, which reduced the spatial and spectral resolution of Large Science Aperture (LSA) observations and decreased the throughput of the Small Science Aperture (SSA) by a factor of two. Periodic problems with the Side 1 carrousel electronics and anomalies with the low-voltage power supply finally resulted in a suspension of the use of Side 1 less than two years after launch. At the outset, the GHRS SSC task involved work in four areas: 1) to manage and operate the GHRS Data Analysis Facility (DAF); 2) to support the second Servicing Mission Observatory Verification (SMOV) program, as well as perform system engineering analysis of the GHRS as nesessary; 3) to assist the GHRS IDT with their scientific research programs, particularly the GSFC members of the team, and 4) to provide administrative and logistic support for GHRS public information and educational activities.

Side-To-Side Nerve Bridges Support Donor Axon Regeneration Into Chronically Denervated Nerves and Are Associated With Characteristic Changes in Schwann Cell Phenotype.

PubMed

Hendry, J Michael; Alvarez-Veronesi, M Cecilia; Snyder-Warwick, Alison; Gordon, Tessa; Borschel, Gregory H

2015-11-01

Chronic denervation resulting from long nerve regeneration times and distances contributes greatly to suboptimal outcomes following nerve injuries. Recent studies showed that multiple nerve grafts inserted between an intact donor nerve and a denervated distal recipient nerve stump (termed "side-to-side nerve bridges") enhanced regeneration after delayed nerve repair. To examine the cellular aspects of axon growth across these bridges to explore the "protective" mechanism of donor axons on chronically denervated Schwann cells. In Sprague Dawley rats, 3 side-to-side nerve bridges were placed over a 10-mm distance between an intact donor tibial (TIB) nerve and a recipient denervated common peroneal (CP) distal nerve stump. Green fluorescent protein-expressing TIB axons grew across the bridges and were counted in cross section after 4 weeks. Immunofluorescent axons and Schwann cells were imaged over a 4-month period. Denervated Schwann cells dedifferentiated to a proliferative, nonmyelinating phenotype within the bridges and the recipient denervated CP nerve stump. As donor TIB axons grew across the 3 side-to-side nerve bridges and into the denervated CP nerve, the Schwann cells redifferentiated to the myelinating phenotype. Bridge placement led to an increased mass of hind limb anterior compartment muscles after 4 months of denervation compared with muscles whose CP nerve was not "protected" by bridges. This study describes patterns of donor axon regeneration and myelination in the denervated recipient nerve stump and supports a mechanism where these donor axons sustain a proregenerative state to prevent deterioration in the face of chronic denervation.

Elements of an environmental decision support system for seasonal wetland salt management in a river basin subjected to water quality regulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quinn, N.W.T.

Seasonally managed wetlands in the Grasslands Basin on the west-side of California's San Joaquin Valley provide food and shelter for migratory wildfowl during winter months and sport for waterfowl hunters during the annual duck season. Surface water supply to these wetlands contain salt which, when drained to the San Joaquin River during the annual drawdown period, can negatively impact water quality and cause concern to downstream agricultural riparian water diverters. Recent environmental regulation, limiting discharges salinity to the San Joaquin River and primarily targeting agricultural non-point sources, now also targets return flows from seasonally managed wetlands. Real-time water quality managementmore » has been advocated as a means of continuously matching salt loads discharged from agricultural, wetland and municipal operations to the assimilative capacity of the San Joaquin River. Past attempts to build environmental monitoring and decision support systems (EDSS's) to implement this concept have enjoyed limited success for reasons that are discussed in this paper. These reasons are discussed in the context of more general challenges facing the successful implementation of a comprehensive environmental monitoring, modelling and decision support system for the San Joaquin River Basin.« less

Controlling coherence in epsilon-near-zero metamaterials (Conference Presentation)

NASA Astrophysics Data System (ADS)

Caglayan, Humeyra; Hajian, Hodjat; Ozbay, Ekmel

2017-05-01

Recently, metamaterials with near-zero refractive index have attracted much attention. Light inside these materials experiences no spatial phase change and extremely large phase velocity, makes these peculiar systems applicable for realizing directional emission, tunneling waveguides, large-area single-mode devices and electromagnetic cloaks. In addition, epsilon-near-zero (ENZ) metamaterials can also enhance light transmission through a subwavelength aperture. Impedance-matched all-dielectric zero-index metamaterials which exhibit Dirac cone dispersions at center of the Brillouin zone, have been experimentally demonstrated at microwave regime and optical frequencies for transverse-magnetic (TM) polarization of light. More recently, it has been also proved that these systems can be realized in a miniaturized in-plane geometry useful for integrated photonic applications, i.e. these metamaterials can be integrated with other optical elements, including waveguides, resonators and interferometers. In this work, using a zero-index metamaterial at the inner and outer sides of a subwavelength aperture, we numerically and experimental study light transmission through and its extraction from the aperture. The metamaterial consists of a combination of two double-layer arrays of scatterers with dissimilar subwavelength dimensions. The metamaterial exhibits zero-index optical response in microwave region. Our numerical investigation shows that the presence of the metamaterial at the inner side of the aperture leads to a considerable increase in the transmission of light through the subwavelength aperture. This enhancement is related to the amplification of the amplitude of the electromagnetic field inside the metamaterial which drastically increases the coupling between free space and the slit. By obtaining the electric field profile of the light passing through the considered NZI/aperture/NZI system at this frequency we found out that in addition to the enhanced transmission there is an excellent beaming of the extracted light from the structure. We have theoretically and experimentally shown that using a zero-index metamaterial at the inner and outer sides of a metallic subwavelength slit can considerably enhance the transmission of light through the aperture and beam its extraction, respectively. This work has been supported by TUBITAK under Project No 114E505. The author H.C. also acknowledges partial support from the Turkish Academy of Sciences.

Evaluation of Detector-to-Detector and Mirror Side Differences for Terra MODIS Reflective Solar Bands Using Simultaneous MISR Observations

NASA Technical Reports Server (NTRS)

Wu, Aisheng; Xiong, Xiaoxiong; Angal, A.; Barnes, W.

2011-01-01

The Moderate Resolution Imaging Spectroradiometer (MODIS) is one of the five Earth-observing instruments on-board the National Aeronautics and Space Administration (NASA) Earth-Observing System(EOS) Terra spacecraft, launched in December 1999. It has 36 spectral bands with wavelengths ranging from 0.41 to 14.4 mm and collects data at three nadir spatial resolutions: 0.25 km for 2 bands with 40 detectors each, 0.5 km for 5 bands with 20 detectors each and 1 km for the remaining 29 bands with 10 detectors each. MODIS bands are located on four separate focal plane assemblies (FPAs) according to their spectral wavelengths and aligned in the cross-track direction. Detectors of each spectral band are aligned in the along-track direction. MODIS makes observations using a two-sided paddle-wheel scan mirror. Its on-board calibrators (OBCs) for the reflective solar bands (RSBs) include a solar diffuser (SD), a solar diffuser stability monitor (SDSM) and a spectral-radiometric calibration assembly (SRCA). Calibration is performed for each band, detector, sub-sample (for sub-kilometer resolution bands) and mirror side. In this study, a ratio approach is applied to MODIS observed Earth scene reflectances to track the detector-to-detector and mirror side differences. Simultaneous observed reflectances from the Multi-angle Imaging Spectroradiometer (MISR), also onboard the Terra spacecraft, are used with MODIS observed reflectances in this ratio approach for four closely matched spectral bands. Results show that the detector-to-detector difference between two adjacent detectors within each spectral band is typically less than 0.2% and, depending on the wavelengths, the maximum difference among all detectors varies from 0.5% to 0.8%. The mirror side differences are found to be very small for all bands except for band 3 at 0.44 mm. This is the band with the shortest wavelength among the selected matching bands, showing a time-dependent increase for the mirror side difference. This study is part of the effort by the MODIS Characterization Support Team (MCST) in order to track the RSB on-orbit performance for MODIS collection 5 data products. To support MCST efforts for future data re-processing, this analysis will be extended to include more spectral bands and temporal coverage.

Noise Measurements of High Aspect Ratio Distributed Exhaust Systems

NASA Technical Reports Server (NTRS)

Bridges, James

2015-01-01

This paper covers far-field acoustic measurements of a family of rectangular nozzles with aspect ratio 8, in the high subsonic flow regime. Several variations of nozzle geometry, commonly proposed for embedded exhaust systems, are explored, including bevels, slants, single broad chevrons and notches, and internal septae. Far-field acoustic results, presented previously for the simple rectangular nozzle, showed that increasing aspect ratio increases the high frequency noise, especially directed in the plane containing the minor axis of the nozzle. Detailed changes to the nozzle geometry generally made little difference in the noise, and the differences were greatest at low speed. Having an extended lip on one broad side ('bevel') did produce up to 3dB more noise in all directions, while extending the lip on the narrow side ('slant') produced up to 2dB more noise, primarily on the side with the extension. Adding a single, non-intrusive chevron, made no significant change to the noise, while inverting the chevron ('notch') produced up to 2dB increase in the noise. Having internal walls ('septae') within the nozzle, such as would be required for structural support or when multiple fan ducts are aggregated, reduced the noise of the rectangular jet, but could produce a highly directional shedding tone from the septae trailing edges. Finally, a nozzle with both septae and a beveled nozzle, representative of the exhaust system envisioned for a distributed propulsion aircraft with a common rectangular duct, produced almost as much noise as the beveled nozzle, with the septae not contributing much reduction in noise.

Noise Measurements of High Aspect Ratio Distributed Exhaust Systems

NASA Technical Reports Server (NTRS)

Bridges, James E.

2015-01-01

This paper covers far-field acoustic measurements of a family of rectangular nozzles with aspect ratio 8, in the high subsonic flow regime. Several variations of nozzle geometry, commonly found in embedded exhaust systems, are explored, including bevels, slants, single broad chevrons and notches, and internal septae. Far-field acoustic results, presented previously for the simple rectangular nozzle, showed that increasing aspect ratio increases the high frequency noise, especially directed in the plane containing the minor axis of the nozzle. Detailed changes to the nozzle geometry generally made little difference in the noise, and the differences were greatest at low speed. Having an extended lip on one broad side (bevel) did produce up to 3 decibels more noise in all directions, while extending the lip on the narrow side (slant) produced up to 2 decibels more noise, primarily on the side with the extension. Adding a single, non-intrusive chevron, made no significant change to the noise, while inverting the chevron (notch) produced up to 2decibels increase in the noise. Having internal walls (septae) within the nozzle, such as would be required for structural support or when multiple fan ducts are aggregated, reduced the noise of the rectangular jet, but could produce a highly directional shedding tone from the septae trailing edges. Finally, a nozzle with both septae and a beveled nozzle, representative of the exhaust system envisioned for a distributed electric propulsion aircraft with a common rectangular duct, produced almost as much noise as the beveled nozzle, with the septae not contributing much reduction in noise.

Critical side channel effects in random bit generation with multiple semiconductor lasers in a polarization-based quantum key distribution system.

PubMed

Ko, Heasin; Choi, Byung-Seok; Choe, Joong-Seon; Kim, Kap-Joong; Kim, Jong-Hoi; Youn, Chun Ju

2017-08-21

Most polarization-based BB84 quantum key distribution (QKD) systems utilize multiple lasers to generate one of four polarization quantum states randomly. However, random bit generation with multiple lasers can potentially open critical side channels that significantly endangers the security of QKD systems. In this paper, we show unnoticed side channels of temporal disparity and intensity fluctuation, which possibly exist in the operation of multiple semiconductor laser diodes. Experimental results show that the side channels can enormously degrade security performance of QKD systems. An important system issue for the improvement of quantum bit error rate (QBER) related with laser driving condition is further addressed with experimental results.

A side-by-side comparison of CPV module and system performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muller, Matthew; Marion, Bill; Kurtz, Sarah

A side-by-side comparison is made between concentrator photovoltaic module and system direct current aperture efficiency data with a focus on quantifying system performance losses. The individual losses measured/calculated, when combined, are in good agreement with the total loss seen between the module and the system. Results indicate that for the given test period, the largest individual loss of 3.7% relative is due to the baseline performance difference between the individual module and the average for the 200 modules in the system. A basic empirical model is derived based on module spectral performance data and the tabulated losses between the modulemore » and the system. The model predicts instantaneous system direct current aperture efficiency with a root mean square error of 2.3% relative.« less

An Integrated Approach to Functional Engineering: An Engineering Database for Harness, Avionics and Software

NASA Astrophysics Data System (ADS)

Piras, Annamaria; Malucchi, Giovanni

2012-08-01

In the design and development phase of a new program one of the critical aspects is the integration of all the functional requirements of the system and the control of the overall consistency between the identified needs on one side and the available resources on the other side, especially when both the required needs and available resources are not yet consolidated, but they are evolving as the program maturity increases.The Integrated Engineering Harness Avionics and Software database (IDEHAS) is a tool that has been developed to support this process in the frame of the Avionics and Software disciplines through the different phases of the program. The tool is in fact designed to allow an incremental build up of the avionics and software systems, from the description of the high level architectural data (available in the early stages of the program) to the definition of the pin to pin connectivity information (typically consolidated in the design finalization stages) and finally to the construction and validation of the detailed telemetry parameters and commands to be used in the test phases and in the Mission Control Centre. The key feature of this approach and of the associated tool is that it allows the definition and the maintenance / update of all these data in a single, consistent environment.On one side a system level and concurrent approach requires the feasibility to easily integrate and update the best data available since the early stages of a program in order to improve confidence in the consistency and to control the design information.On the other side, the amount of information of different typologies and the cross-relationships among the data imply highly consolidated structures requiring lot of checks to guarantee the data content consistency with negative effects on simplicity and flexibility and often limiting the attention to special needs and to the interfaces with other disciplines.

Single-step simultaneous side-by-side placement of a self-expandable metallic stent with a 6-Fr delivery system for unresectable malignant hilar biliary obstruction: a feasibility study.

PubMed

Kawakubo, Kazumichi; Kawakami, Hiroshi; Kuwatani, Masaki; Kudo, Taiki; Abe, Yoko; Kawahata, Shuhei; Kubo, Kimitoshi; Kubota, Yoshimasa; Sakamoto, Naoya

2015-02-01

Bilateral self-expandable metallic stent (SEMS) placement for the management of unresectable malignant hilar biliary obstruction (UMHBO) is technically challenging to perform using the existing metallic stents with thick delivery systems. The recently developed 6-Fr delivery systems could facilitate a single-step simultaneous side-by-side placement through the accessory channel of the duodenoscope. The aim of this study was to evaluate the feasibility of this procedure. Between May and September 2013, 13 consecutive patients with UMHBO underwent a single-step simultaneous side-by-side placement of SEMS with the 6-Fr delivery system. The technical success rate, stent patency, and rate of complications were evaluated from the prospectively collected database. Technical success was achieved in 11 (84.6%, 95% confidence interval [CI]: 57.8-95.8) patients. The median procedure time was 25 min. Early and late complications were observed in 23% (one segmental cholangitis and two liver abscesses) and 15% (one segmental cholangitis and one cholecystitis) patients, respectively. Median dysfunction free patency was 263 days (95% CI: 37-263). Five patients (38%) experienced stent occlusion that was successfully managed by endoscopic stent placement. A single-step simultaneous side-by-side placement of SEMS with a 6-Fr delivery system was feasible for the management of UMHBO. © 2014 Japanese Society of Hepato-Biliary-Pancreatic Surgery.

The Sensitivity to Trans-Neptunian Dwarf Planets of the Siding Spring Survey

NASA Astrophysics Data System (ADS)

Bannister, Michele; Brown, M. E.; Schmidt, B. P.; Francis, P.; McNaught, R.; Garrad, G.; Larson, S.; Beshore, E.

2012-10-01

The last decade has seen considerable effort in assessing the populations of icy worlds in the outer Solar System, with major surveys in the Northern and more recently, in the Southern Hemisphere skies. Our archival search of more than ten thousand square degrees of sky south of the ecliptic observed over five years is a bright-object survey, sensitive to dwarf-planet sized trans-Neptunian objects. Our innovative survey analyses observations of the Siding Spring Survey, an ongoing survey for near-Earth asteroids at the 0.5 m Uppsala telescope at Siding Spring Observatory. This survey observed each of 2300 4.55 square degree fields on between 30 and 90 of the nights from early 2004 to late 2009, creating a dataset with dense temporal coverage, which we reprocessed for TNOs with a dedicated pipeline. We assess our survey's sensitivity to trans-Neptunian objects by simulating the observation of the synthetic outer Solar System populations of Grav et al. (2011): Centaurs, Kuiper belt and scattered disk. As our fields span approx. -15 to -70 declination, avoiding the galactic plane by 10 degrees either side, we are particularly sensitive to dwarf planets in high-inclination orbits. Partly due to this coverage far from the ecliptic, all known dwarf planets, including Pluto, do fall outside our survey coverage in its temporal span. We apply the widest plausible range of absolute magnitudes to each observable synthetic object, measuring each subsequent apparent magnitude against the magnitude depth of the survey observations. We evaluate our survey's null detection of new dwarf planets in light of our detection efficiencies as a function of trans-Neptunian orbital parameter space. MTB appreciates the funding support of the Joan Duffield Postgraduate Scholarship, an Australian Postgraduate Award, and the Astronomical Society of Australia.

The Application of Auto-Disturbance Rejection Control Optimized by Least Squares Support Vector Machines Method and Time-Frequency Representation in Voltage Source Converter-High Voltage Direct Current System.

PubMed

Liu, Ying-Pei; Liang, Hai-Ping; Gao, Zhong-Ke

2015-01-01

In order to improve the performance of voltage source converter-high voltage direct current (VSC-HVDC) system, we propose an improved auto-disturbance rejection control (ADRC) method based on least squares support vector machines (LSSVM) in the rectifier side. Firstly, we deduce the high frequency transient mathematical model of VSC-HVDC system. Then we investigate the ADRC and LSSVM principles. We ignore the tracking differentiator in the ADRC controller aiming to improve the system dynamic response speed. On this basis, we derive the mathematical model of ADRC controller optimized by LSSVM for direct current voltage loop. Finally we carry out simulations to verify the feasibility and effectiveness of our proposed control method. In addition, we employ the time-frequency representation methods, i.e., Wigner-Ville distribution (WVD) and adaptive optimal kernel (AOK) time-frequency representation, to demonstrate our proposed method performs better than the traditional method from the perspective of energy distribution in time and frequency plane.

The Application of Auto-Disturbance Rejection Control Optimized by Least Squares Support Vector Machines Method and Time-Frequency Representation in Voltage Source Converter-High Voltage Direct Current System

PubMed Central

Gao, Zhong-Ke

2015-01-01

In order to improve the performance of voltage source converter-high voltage direct current (VSC-HVDC) system, we propose an improved auto-disturbance rejection control (ADRC) method based on least squares support vector machines (LSSVM) in the rectifier side. Firstly, we deduce the high frequency transient mathematical model of VSC-HVDC system. Then we investigate the ADRC and LSSVM principles. We ignore the tracking differentiator in the ADRC controller aiming to improve the system dynamic response speed. On this basis, we derive the mathematical model of ADRC controller optimized by LSSVM for direct current voltage loop. Finally we carry out simulations to verify the feasibility and effectiveness of our proposed control method. In addition, we employ the time-frequency representation methods, i.e., Wigner-Ville distribution (WVD) and adaptive optimal kernel (AOK) time-frequency representation, to demonstrate our proposed method performs better than the traditional method from the perspective of energy distribution in time and frequency plane. PMID:26098556

Health Information Technology Systems profoundly impact users: a case study in a dental school.

PubMed

Hill, Heather K; Stewart, Denice C L; Ash, Joan S

2010-04-01

The purpose of this study was to increase our understanding of the impact of Health Information Technology Systems (HITS) on dental school users when the systems are integrated into chair-side patient care. We used qualitative research methods, including interviews, focus groups, and observations, to capture the experiences of HITS users at a single institution. Users included administrators, clinical faculty members, predoctoral students, support staff, and residents. The data were analyzed using a grounded theory approach, and nine themes emerged: 1) HITS benefits were disproportionate among users; 2) communicating about the HITS was challenging; 3) users experienced a range of strong emotions; 4) the instructor persona diminished; 5) there were shifts in the school's power structure; 6) allocation of end-users' time shifted; 7) the training and support needs of end-users were significant; 8) perceived lack of HITS usability made documentation cumbersome for clinicians; and 9) clinicians' workflow was disrupted. HITS integration into patient care impacts the work of all system users, especially end-users. The themes highlight areas of potential concern for implementers and users in integrating a HITS into patient care.

Electrolyzers Enhancing Flexibility in Electric Grids

DOE PAGES

Mohanpurkar, Manish; Luo, Yusheng; Terlip, Danny; ...

2017-11-10

This paper presents a real-time simulation with a hardware-in-the-loop (HIL)-based approach for verifying the performance of electrolyzer systems in providing grid support. Hydrogen refueling stations may use electrolyzer systems to generate hydrogen and are proposed to have the potential of becoming smarter loads that can proactively provide grid services. On the basis of experimental findings, electrolyzer systems with balance of plant are observed to have a high level of controllability and hence can add flexibility to the grid from the demand side. A generic front end controller (FEC) is proposed, which enables an optimal operation of the load on themore » basis of market and grid conditions. This controller has been simulated and tested in a real-time environment with electrolyzer hardware for a performance assessment. It can optimize the operation of electrolyzer systems on the basis of the information collected by a communication module. Real-time simulation tests are performed to verify the performance of the FEC-driven electrolyzers to provide grid support that enables flexibility, greater economic revenue, and grid support for hydrogen producers under dynamic conditions. In conclusion, the FEC proposed in this paper is tested with electrolyzers, however, it is proposed as a generic control topology that is applicable to any load.« less

Side effects during subcutaneous immunotherapy in children with allergic diseases.

PubMed

Tophof, Max A; Hermanns, Anne; Adelt, Thomas; Eberle, Peter; Gronke, Christine; Friedrichs, Frank; Knecht, Roland; Mönter, Ernst; Schöpfer, Helmut; Schwerk, Nicolaus; Steinbach, Jörg; Umpfenbach, Hans-Ulrich; Weißhaar, Christian; Wilmsmeyer, Brigitte; Bufe, Albrecht

2018-05-01

Allergen-specific immunotherapy is the only causal form of therapy for IgE-mediated allergic diseases. Subcutaneous immunotherapy (SCIT) is considered safe and well tolerated in adults, yet there is less evidence of safety in the pediatric population. A non-interventional prospective observing longitudinal study was carried out to determine the incidence of local and systemic side effects by SCIT, routinely performed in pediatric patients. A total of 581 pediatric patients were observed in 18 study centers between March 2012 and October 2014, recording 8640 treatments and 10 015 injections. A total of 54.6% of the patients experienced immediate local side effects at least once; delayed local side effects were seen in 56.1%. Immediate systemic adverse reactions occurred in 2.2% of patients; 7.4% experienced delayed systemic side effects. However, severe systemic side effects (grade III in the classification of Ring and Messmer) were seen in 0.03% of all treatments, all appearing within 30 minutes after the injections. No grade IV reactions were observed. In addition, many potential risk factors were investigated, yet only a few were found to be associated with the occurrence of side effects. Subcutaneous immunotherapy is a safe form of therapy in pediatric patients, with similar rates of local side effects compared to adult patients and low rates of severe systemic side effects. However, local and systemic reactions occurring later than 30 minutes after injection were observed more often than expected, which makes it essential to be attentive on behalf of pediatricians, patients, and parents. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Palliative Care Specialist Consultation Is Associated With Supportive Care Quality in Advanced Cancer.

PubMed

Walling, Anne M; Tisnado, Diana; Ettner, Susan L; Asch, Steven M; Dy, Sydney M; Pantoja, Philip; Lee, Martin; Ahluwalia, Sangeeta C; Schreibeis-Baum, Hannah; Malin, Jennifer L; Lorenz, Karl A

2016-10-01

Although recent randomized controlled trials support early palliative care for patients with advanced cancer, the specific processes of care associated with these findings and whether these improvements can be replicated in the broader health care system are uncertain. The aim of this study was to evaluate the occurrence of palliative care consultation and its association with specific processes of supportive care in a national cohort of Veterans using the Cancer Quality ASSIST (Assessing Symptoms Side Effects and Indicators of Supportive Treatment) measures. We abstracted data from 719 patients' medical records diagnosed with advanced lung, colorectal, or pancreatic cancer in 2008 over a period of three years or until death who received care in the Veterans Affairs Health System to evaluate the association of palliative care specialty consultation with the quality of supportive care overall and by domain using a multivariate regression model. All but 54 of 719 patients died within three years and 293 received at least one palliative care consult. Patients evaluated by a palliative care specialist at diagnosis scored seven percentage points higher overall (P < 0.001) and 11 percentage points higher (P < 0.001) within the information and care planning domain compared with those without a consult. Early palliative care specialist consultation is associated with better quality of supportive care in three advanced cancers, predominantly driven by improvements in information and care planning. This study supports the effectiveness of early palliative care consultation in three common advanced cancers within the Veterans Affairs Health System and provides a greater understanding of what care processes palliative care teams influence. Published by Elsevier Inc.

2.1 meter (82 inch) Slip Ring By-Pass Project

NASA Astrophysics Data System (ADS)

Bryan, Corby B.

2006-12-01

2.1 meter (82 inch) Slip Ring By-Pass Project I will describe a project to bypass the old method of getting control communications above the rotation point of the McDonald Observatory 2.1 meter dome. The old method used slip rings that were implemented in the late 1930s. The new system uses wireless serial commands which allow the control lines to be taken off the slip rings, leaving only power and ground. I will describe how the concept was devised so the slip rings could be by-passed, what micro-controller system that was decided on and used, how the wireless units were set up and finally how the system was tested and put in place with only limited tasks to control. (I.E. the opening and closing of the shutters) We describe the advantages to making this upgrade and how it could benefit any telescope interested in upgrading its communication systems. This project was designed and tested in ten weeks during the McDonald Observatory REU and was supported under NSF AST-0243745. The system was designed so that it could be installed while running side by side with the current method of getting control to the above rotation point. The method is still in place being tested on the 2.1 meter telescope and will soon be fully implemented by the University of Texas McDonald Observatory OS staff.

Reducing nurses'. Workload using a computerized nursing support system linked to the hospital information system.

PubMed

Ito, C; Satoh, I; Michiya, H; Kitayama, Y; Miyazaki, K; Ota, S; Satoh, H; Sakurai, T; Shirato, H; Miyasaka, K

1997-01-01

A computerised nursing support system (CNSS) linked to the hospital information system (HIS) was developed and has been in use for one year, in order to reduce the workload of nurses. CNSS consists of (1) a hand held computer for each nurse (2) desk-top computers in the nurses' station and doctors' rooms (3) a data server (4) an interface with the main hospital information system. Nurses enter vital signs, food intake and other information about the patients into the hand held computer at the bed-side. The information is then sent automatically to the CNSS data server, which also receives patients' details (prescribed medicines etc.) from the HIS. Nurses and doctors can see all the information on the desk-top and hand held computers. This system was introduced in May 1995 into a university hospital ward with 40 beds. A questionnaire was completed by 23 nurses before and after the introduction of CNSS. The mean time required to post vital data was significantly reduced from 121 seconds to 54 seconds (p < 0.01). After three months 30% of nurses felt CNSS had reduced their workload, while 30% felt it had complicated their work; after five months 70% noted a reduction and 0% reported that CNSS had made their work more complex. The study therefore concludes that the interface between a computerised nursing support system and the hospital information system reduced the workload of nurses.

Advances in Orion's On-Orbit Guidance and Targeting System Architecture

NASA Technical Reports Server (NTRS)

Scarritt, Sara K.; Fill, Thomas; Robinson, Shane

2015-01-01

NASA's manned spaceflight programs have a rich history of advancing onboard guidance and targeting technology. In order to support future missions, the guidance and targeting architecture for the Orion Multi-Purpose Crew Vehicle must be able to operate in complete autonomy, without any support from the ground. Orion's guidance and targeting system must be sufficiently flexible to easily adapt to a wide array of undecided future missions, yet also not cause an undue computational burden on the flight computer. This presents a unique design challenge from the perspective of both algorithm development and system architecture construction. The present work shows how Orion's guidance and targeting system addresses these challenges. On the algorithm side, the system advances the state-of-the-art by: (1) steering burns with a simple closed-loop guidance strategy based on Shuttle heritage, and (2) planning maneuvers with a cutting-edge two-level targeting routine. These algorithms are then placed into an architecture designed to leverage the advantages of each and ensure that they function in concert with one another. The resulting system is characterized by modularity and simplicity. As such, it is adaptable to the on-orbit phases of any future mission that Orion may attempt.

Demand-side management glossary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Isaksen, L.; Ignelzi, P.C.

1992-10-01

Demand-side management (DSM) plays an increasingly important role in helping utilities meet capacity needs while addressing important customer service issues. In implementing utility-specific programs, however, DSM professionals have created an entire vocabulary of words and phrases that are often used and interpreted in very different ways by people with similar utility planning backgrounds. Such inconsistent terminology can hamper the very communication DSM seeks to support. Thus, this report-the first of its kind-presents a glossary of DSM terms, grouped under five major categories: (1) utility systems, (2) programs and techniques, (3) costs, revenues, and rates, (4) modeling and analysis, and (5)more » marketing. An index facilitates the rapid search for key words. This glossary together with a complimentary report entitled, Electric Utility DSM Programs: Terminology and Reporting Formats attempts to define some of the most common terms used in DSM today.« less

Demand-side management glossary. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Isaksen, L.; Ignelzi, P.C.

1992-10-01

Demand-side management (DSM) plays an increasingly important role in helping utilities meet capacity needs while addressing important customer service issues. In implementing utility-specific programs, however, DSM professionals have created an entire vocabulary of words and phrases that are often used and interpreted in very different ways by people with similar utility planning backgrounds. Such inconsistent terminology can hamper the very communication DSM seeks to support. Thus, this report-the first of its kind-presents a glossary of DSM terms, grouped under five major categories: (1) utility systems, (2) programs and techniques, (3) costs, revenues, and rates, (4) modeling and analysis, and (5)more » marketing. An index facilitates the rapid search for key words. This glossary together with a complimentary report entitled, Electric Utility DSM Programs: Terminology and Reporting Formats attempts to define some of the most common terms used in DSM today.« less

Lateral polarity control of III-nitride thin film and application in GaN Schottky barrier diode

NASA Astrophysics Data System (ADS)

Li, Junmei; Guo, Wei; Sheikhi, Moheb; Li, Hongwei; Bo, Baoxue; Ye, Jichun

2018-05-01

N-polar and III-polar GaN and AlN epitaxial thin films grown side by side on single sapphire substrate was reported. Surface morphology, wet etching susceptibility and bi-axial strain conditions were investigated and the polarity control scheme was utilized in the fabrication of Schottky barrier diode where ohmic contact and Schottky contact were deposited on N-polar domains and Ga-polar domains, respectively. The influence of N-polarity on on-state resistivity and I–V characteristic was discussed, demonstrating that lateral polarity structure of GaN and AlN can be widely used in new designs of optoelectronic and electronic devices. Project partially supported by the National Key Research and Development Program of China (No. 2016YFB0400802), the National Natural Science Foundation of China (No. 61704176), and the Open project of Zhejiang Key Laboratory for Advanced Microelectronic Intelligent Systems and Applications (No. ZJUAMIS1704).

Comparing the aerodynamic forces produced by dragonfly forewings during inverted and non-inverted flight

NASA Astrophysics Data System (ADS)

Shumway, Nathan; Gabryszuk, Mateusz; Laurence, Stuart

2017-11-01

Experiments were conducted with live dragonflies to determine their wing kinematics during free flight. The motion of one forewing in two different tests, one where the dragonfly is inverted, is described using piecewise functions and simulated using the OVERTURNS Reynolds-averaged Navier-Stokes solver that has been used in previous work to determine trim conditions for a fruit fly model. For the inverted dragonfly the upstrokes were significantly longer than the downstrokes, pitching amplitude is lower than that for the right-side up flight and the flap amplitude is larger. Simulations of dragonfly kinematics of a single forewing are presented to determine how the forces differ for a dragonfly flying inverted and a dragonfly flying right-side up. This work was supported by the United States Army Research Laboratory's Micro Autonomous Systems and Technology Collaborative Technology Alliance Project MCE-16-17 1.2.

Cooling system for three hook ring segment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Campbell, Christian X.; Eng, Darryl; Lee, Ching-Pang

2014-08-26

A triple hook ring segment including forward, midsection and aft mounting hooks for engagement with respective hangers formed on a ring segment carrier for supporting a ring segment panel, and defining a forward high pressure chamber and an aft low pressure chamber on opposing sides of the midsection mounting hook. An isolation plate is provided on the aft side of the midsection mounting hook to form an isolation chamber between the aft low pressure chamber and the ring segment panel. High pressure air is supplied to the forward chamber and flows to the isolation chamber through crossover passages in themore » midsection hook. The isolation chamber provides convection cooling air to an aft portion of the ring segment panel and enables a reduction of air pressure in the aft low pressure chamber to reduce leakage flow of cooling air from the ring segment.« less

Magnetic translator bearings

NASA Technical Reports Server (NTRS)

Hockney, Richard L. (Inventor); Downer, James R. (Inventor); Eisenhaure, David B. (Inventor); Hawkey, Timothy J. (Inventor); Johnson, Bruce G. (Inventor)

1990-01-01

A magnetic bearing system for enabling translational motion includes a carriage and a shaft for movably supporting the carriage; a first magnetic bearing fixed to one of the carriage and shaft and slidably received in a first channel of the other of the carriage and shaft. The first channel is generally U shaped with two side walls and a back wall. The magnetic bearing includes a pair of spaced magnetic pole pieces, each pole piece having a pair of electromagnetic coils mounted on poles on opposite ends of the pole piece proximate the side walls, and a third electromagnetic coil mounted on a pole of the pole piece proximate the backwall; a motion sensor for sensing translational motion along two axes and rotationally about three axes of the carriage and shaft relative to each other; and a correction circuit responsive to the sensor for generating a correction signal to drive the coils to compensate for any misalignment sensed between the carriage and the shaft.

Torsion bar stabilizer for a vehicle and method for mounting the stabilizer on the vehicle frame

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sauber, C.J.

This patent describes a method of mounting a stabilizing mechanism on a vehicle frame which is supported and biased on a suspension assembly at opposite sides of the frame. The frame includes overload stops riveted to opposite sides of the frame and the suspension assembly includes bracket assemblies which secure the vehicle's suspension springs to a wheel axle. The method comprises the following steps: removing an overload stop from each side of the vehicle frame; mounting a modified overload stop on each side of the frame which serves as both an overload stop and a support for the stabilizing mechanismmore » wherein the modified overload stop is mounted into the holes in the frame left from the removal of the overload stop; removing from each side of the vehicle the top bracket from the bracket assembly; inserting a modified top bracket into each bracket assembly wherein the top bracket assembly is modified to couple with the stabilizing mechanism; and mounting on the modified overload stops a torsion bar whose opposite ends are coupled to the modified top bracket by way of linkages.« less

What matters when judging intentionality-moral content or normative status? Testing the rational scientist model of the side-effect.

PubMed

Papadopoulos, C; Hayes, B K

2018-06-01

Previous work has demonstrated a "side-effect effect," such that intentionality is more likely to be attributed to agents who bring about negatively valenced as opposed to positively valenced side effects. The rational-scientist model explains this by suggesting that norm-violating side effects are more informative for inferring intentionality than norm-conforming side effects. In the present study we reexamined this account, addressing limitations of previous empirical tests (e.g., Uttich & Lombrozo, Cognition 116: 87-100, 2010). Side-effect valence and norm status were manipulated factorially, enabling an examination of the impact of norm status on intentionality judgments in both positively and negatively valenced side effects. Additionally, the impact of side-effect norm status on the perceived valences of side effects and agents was examined. Effects of norm status were found for both positive and negative side effects. Violation of an ostensibly neutral norm led to negative perceptions of the side effect. However, a norm status effect on intentionality judgments persisted when these effects were controlled. These results support the view that the side-effect effect is the result of the rational use of social-cognitive evidence.

Novel Straight Road Driving Control of Power Assisted Wheelchair Based on Disturbance Estimation of Right and Left Wheels

NASA Astrophysics Data System (ADS)

Seki, Hirokazu; Sugimoto, Takeaki; Tadakuma, Susumu

This paper describes a novel straight road driving control scheme of power assisted wheelchair. Power assisted wheelchair which assists the driving force by electric motors is expected to be widely used as a mobility support system for elderly people and disabled people. The straight driving can be prevented by the road conditions such as branches, grass and carpets because the right and left wheels drive independently. This paper proposes a straight road driving control system based on the disturbance torque estimation. The proposed system estimates the difference of the driving torque by disturbance torque observer and compensates to one side of the wheels. Some practical driving experiments on various road conditions show the effectiveness of the proposed control system.

Extending Climate Analytics-As to the Earth System Grid Federation

NASA Astrophysics Data System (ADS)

Tamkin, G.; Schnase, J. L.; Duffy, D.; McInerney, M.; Nadeau, D.; Li, J.; Strong, S.; Thompson, J. H.

2015-12-01

We are building three extensions to prior-funded work on climate analytics-as-a-service that will benefit the Earth System Grid Federation (ESGF) as it addresses the Big Data challenges of future climate research: (1) We are creating a cloud-based, high-performance Virtual Real-Time Analytics Testbed supporting a select set of climate variables from six major reanalysis data sets. This near real-time capability will enable advanced technologies like the Cloudera Impala-based Structured Query Language (SQL) query capabilities and Hadoop-based MapReduce analytics over native NetCDF files while providing a platform for community experimentation with emerging analytic technologies. (2) We are building a full-featured Reanalysis Ensemble Service comprising monthly means data from six reanalysis data sets. The service will provide a basic set of commonly used operations over the reanalysis collections. The operations will be made accessible through NASA's climate data analytics Web services and our client-side Climate Data Services (CDS) API. (3) We are establishing an Open Geospatial Consortium (OGC) WPS-compliant Web service interface to our climate data analytics service that will enable greater interoperability with next-generation ESGF capabilities. The CDS API will be extended to accommodate the new WPS Web service endpoints as well as ESGF's Web service endpoints. These activities address some of the most important technical challenges for server-side analytics and support the research community's requirements for improved interoperability and improved access to reanalysis data.

Open ended tubing cutters

NASA Technical Reports Server (NTRS)

Girala, A. S. (Inventor)

1981-01-01

A self clamping cutting tool which includes a handle attached to a C-shaped housing is described. Rotatably mounted within the housing is a C-shaped tool body carrying a set of clamping rolls, two support rolls, and an edged cutting roll (64). The support rolls are disposed to one side of the axis of a pipe and the cutting roll is disposed to the other side of a pipe axis so that these rolls contact a pipe at three circumferential points. Cutter advancing apparatus advance the cutting roll toward the support rollers. The support rolls and cutting roll are rotatable independently of the C-shaped housing. A one way ratchet mechanism disposed between the C-shaped housing and the C-shaped tool body permits operation by movement in one rotational direction about the pipe axis.

Approach-related lesions of the sympathetic chain in anterior correction and instrumentation of idiopathic scoliosis

PubMed Central

Adolphs, Bastian; Oberdiek, Denise; Osada, Nani; Liljenqvist, Ulf; Filler, Timm J.; Marziniak, Martin; Bullmann, Viola

2010-01-01

During anterior scoliosis instrumentation with a dual-rod system, the vertebrae are dissected anterolaterally. After surgery, some patients report a change in temperature perception and perspiration in the lower extremities. Sympathetic lesions might be an explanation for this. The aim of this clinical study was to investigate sympathetic function after anterior scoliosis instrumentation. A total of 24 female patients with idiopathic scoliosis (mean age at follow-up, 23.8 years) who had undergone anterior instrumentation on average 6.6 years earlier were included. Due to the suspected relevance of the sympathetic L2 ganglion, two groups were created: a T12 group, in which instrumentation down to T12 was carried out (n = 12), and an L3 group, in which instrumentation down to L3 was done (n = 12). Sympathetic function was assessed by measuring skin temperature at the back of the foot, a plantar ninhydrin sweat test and sympathetic skin responses (SSRs) following electrical stimulation. The side on which the surgical approach was carried out was compared with the contralateral, control side. Health-related quality of life was investigated using the Scoliosis Research Society SRS-22 patient questionnaire. In the T12 group, mean temperatures of 29.6°C on the side of the approach versus 29.5°C on the control side were measured (P > 0.05); in the L3 group, the mean temperatures were 33.2°C on the approach side versus 30.5°C on the control side (P = 0.001). A significant difference between the T12 group and the L3 group (P < 0.001) was observed on the approach side, but not on the control side (P = 0.15). The ninhydrin sweat test showed reduced perspiration in 11 of 12 patients in the L3 group on the approach side in comparison with the control side (P = 0.002). In the T12 group, no significant differences were noted between the left and right feet. SSRs differed significantly between the two groups (P = 0.005). They were detected in all nine analyzable patients in the T12 group on both sides. In the L3 group, they were found on the approach side only in 4 of 11 analyzable patients versus 11 patients on the control side. The results of the SRS-22 questionnaire did not show any significant differences between the two groups. In conclusion, anterior scoliosis instrumentation with a dual-rod system including vertebrae down to L3 regularly leads to lesions in the sympathetic trunk. These are detectable with an increase in temperature, reduced perspiration and reduced SSRs. The caudal level of instrumentation (T12 vs. L3) has an impact on the extent of impairment, supporting the suspected importance of the L2 ganglion. The clinical outcome does not seem to be significantly limited by sympathetic trunk lesions. PMID:20502925

Joint Planning Of Energy Storage and Transmission Considering Wind-Storage Combined System and Demand Side Response

NASA Astrophysics Data System (ADS)

Huang, Y.; Liu, B. Z.; Wang, K. Y.; Ai, X.

2017-12-01

In response to the new requirements of the operation mode of wind-storage combined system and demand side response for transmission network planning, this paper presents a joint planning of energy storage and transmission considering wind-storage combined system and demand side response. Firstly, the charge-discharge strategy of energy storage system equipped at the outlet of wind farm and demand side response strategy are analysed to achieve the best comprehensive benefits through the coordination of the two. Secondly, in the general transmission network planning model with wind power, both energy storage cost and demand side response cost are added to the objective function. Not only energy storage operation constraints and but also demand side response constraints are introduced into the constraint condition. Based on the classical formulation of TEP, a new formulation is developed considering the simultaneous addition of the charge-discharge strategy of energy storage system equipped at the outlet of the wind farm and demand side response strategy, which belongs to a typical mixed integer linear programming model that can be solved by mature optimization software. The case study based on the Garver-6 bus system shows that the validity of the proposed model is verified by comparison with general transmission network planning model. Furthermore, the results demonstrate that the joint planning model can gain more economic benefits through setting up different cases.

Hitchhiker capabilities

NASA Technical Reports Server (NTRS)

Goldsmith, Theodore C.

1988-01-01

A carrier system has been developed for economical and quick response flight of small attached payloads on the space shuttle. Hitchhiker can accommodate up to 750 lb of customer payloads in canisters or mounted to an exposed side-mount plate, or up to 1200 lb mounted on a cross-bay structure. The carrier connects to the orbiter's electrical systems and provides up to six customers with standard electrical services including power, real time telemetry and commands. A transparent data and command system concept is employed to allow the customer to easily use his own ground support equipment and personnel to control his payload during integration and flight operations. A general description of the Hitchhiker program and the Shuttle Payload of Opportunity Carrier (SPOC) is given and future enhancements are outlined.

Development of the oxytalan fiber system in the periodontal space of rat incisors.

PubMed

Inoue, Kouji; Hara, Yaiko; Kuroda, Noriyuki; Sato, Tetsuji

2013-10-01

The present study clarifies developmental organization of the oxytalan fiber system in the periodontal space of both the enamel (labial) and cementum (lingual) sides of rat incisors. The number of oxytalan fibers per unit area (μm(2)) was counted in rat incisors at stages of embryonic day 20 (E20) to postnatal day 35 (P35). Oxytalan fibers in the periodontal space of the enamel side were apt to decrease in number during the postnatal period, whereas their number remained almost unchanged on the cementum side during the developmental period. When the incisor emerged through the gum at P11, thinner oxytalan fibers distributed in the apical growing periodontium of the cementum side seemed to be fused with one another to become thicker fibers as has been reported for rat molars (Inoue et al., 2012). Thus, the oxytalan fiber system in the periodontal space represented significant differences in its distributional density between the enamel and cementum sides after E23. At the stage of P35, oxytalan fibers presented significantly denser distribution in all territories of the periodontal ligament of the cementum side versus the enamel side. The present findings claim that the oxytalan fiber system might bind the tooth to the periodontal ligament and provide equilibrium of vascular system and control of blood flow in the periodontal ligament of the cementum side, while it might exclusively regulate the high level of physiologically adapted vasculature in the periodontal space of the enamel side. Copyright © 2013 Elsevier GmbH. All rights reserved.

CHECKPOINT INHIBITOR IMMUNE THERAPY: Systemic Indications and Ophthalmic Side Effects.

PubMed

Dalvin, Lauren A; Shields, Carol L; Orloff, Marlana; Sato, Takami; Shields, Jerry A

2018-06-01

To review immune checkpoint inhibitor indications and ophthalmic side effects. A literature review was performed using a PubMed search for publications between 1990 and 2017. Immune checkpoint inhibitors are designed to treat system malignancies by targeting one of three ligands, leading to T-cell activation for attack against malignant cells. These ligands (and targeted drug) include cytotoxic T-lymphocyte antigen-4 (CTLA-4, ipilimumab), programmed death protein 1 (PD-1, pembrolizumab, nivolumab), and programmed death ligand-1 (PD-L1, atezolizumab, avelumab, durvalumab). These medications upregulate the immune system and cause autoimmune-like side effects. Ophthalmic side effects most frequently manifest as uveitis (1%) and dry eye (1-24%). Other side effects include myasthenia gravis (n = 19 reports), inflammatory orbitopathy (n = 11), keratitis (n = 3), cranial nerve palsy (n = 3), optic neuropathy (n = 2), serous retinal detachment (n = 2), extraocular muscle myopathy (n = 1), atypical chorioretinal lesions (n = 1), immune retinopathy (n = 1), and neuroretinitis (n = 1). Most inflammatory side effects are managed with topical or periocular corticosteroids, but advanced cases require systemic corticosteroids and cessation of checkpoint inhibitor therapy. Checkpoint inhibitors enhance the immune system by releasing inhibition on T cells, with risk of autoimmune-like side effects. Ophthalmologists should include immune-related adverse events in their differential when examining cancer patients with new ocular symptoms.

Gait training with partial body weight support during overground walking for individuals with chronic stroke: a pilot study

PubMed Central

2011-01-01

Background It is not yet established if the use of body weight support (BWS) systems for gait training is effective per se or if it is the combination of BWS and treadmill that improves the locomotion of individuals with gait impairment. This study investigated the effects of gait training on ground level with partial BWS in individuals with stroke during overground walking with no BWS. Methods Twelve individuals with chronic stroke (53.17 ± 7.52 years old) participated of a gait training program with BWS during overground walking, and were evaluated before and after the gait training period. In both evaluations, individuals were videotaped walking at a self-selected comfortable speed with no BWS. Measurements were obtained for mean walking speed, step length, stride length and speed, toe-clearance, durations of total double stance and single-limb support, and minimum and maximum foot, shank, thigh, and trunk segmental angles. Results After gait training, individuals walked faster, with symmetrical steps, longer and faster strides, and increased toe-clearance. Also, they displayed increased rotation of foot, shank, thigh, and trunk segmental angles on both sides of the body. However, the duration of single-limb support remained asymmetrical between each side of the body after gait training. Conclusions Gait training individuals with chronic stroke with BWS during overground walking improved walking in terms of temporal-spatial parameters and segmental angles. This training strategy might be adopted as a safe, specific and promising strategy for gait rehabilitation after stroke. PMID:21864373

Summary of oceanographic and water-quality measurements in Chincoteague Bay, Maryland and Virginia, 2014–15

USGS Publications Warehouse

Suttles, Steven E.; Ganju, Neil K.; Brosnahan, Sandra M.; Montgomery, Ellyn T.; Dickhudt, Patrick J.; Beudin, Alexis; Nowacki, Daniel J.; Martini, Marinna A.

2017-05-25

U.S. Geological Survey scientists and technical support staff measured oceanographic, waterquality, seabed-elevation-change, and meteorological parameters in Chincoteague Bay, Maryland and Virginia, during the period of August 13, 2014, to July 14, 2015, as part of the Estuarine Physical Response to Storms project (GS2–2D) supported by the Department of the Interior Hurricane Sandy recovery program. These measurements provide time series data that quantify the response and can be used to better understand the resilience of this back-barrier estuarine system to storms. The Assateague Island National Seashore (National Park Service) and the Chincoteague National Wildlife Refuge (U.S. Fish and Wildlife Service) are on the east side of Chincoteague Bay.

Research on the full life cycle management system of smart electric energy meter

NASA Astrophysics Data System (ADS)

Chen, Xiangqun; Huang, Rui; Shen, Liman; Guo, Dingying; Xiong, Dezhi; Xiao, Xiangqi; Liu, Mouhai; Renheng, Xu

2018-02-01

At present, China’s smart electric energy meter life management is started from the procurement and acceptance. The related monitoring and management of the manufacturing sector has not yet been carried out. This article applies RFID technology and network cloud platform to full life cycle management system of smart electric energy meters, builds this full life cycle management system including design and manufacturing, process control, measurement and calibration testing, storage management, user acceptance, site operation, maintenance scrap and other aspects. Exploring smart electric energy meters on-line and off-line communication by the application of active RFID communication functions, and the actual functional application such as local data exchange and instrument calibration. This system provides technical supports on power demand side management and the improvement of smart electric energy meter reliability evaluation system.

Operating Experience and Lessons Learned in the Use of Soft-Sided Packaging for Transportation and Disposal of Low Activity Radioactive Waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kapoor, A.; Gordon, S.; Goldston, W.

2013-07-08

This paper describes the operating experience and lessons learned at U.S. Department of Energy (DOE) sites as a result of an evaluation of potential trailer contamination and soft-sided packaging integrity issues related to the disposal of low-level and mixed low-level (LLW/MLLW) radioactive waste shipments. Nearly 4.3 million cubic meters of LLW/MLLW will have been generated and disposed of during fiscal year (FY) 2010 to FY 2015—either at commercial disposal sites or disposal sites owned by DOE. The LLW/MLLW is packaged in several different types of regulatory compliant packaging and transported via highway or rail to disposal sites safely and efficientlymore » in accordance with federal, state, and local regulations and DOE orders. In 1999, DOE supported the development of LLW containers that are more volumetrically efficient, more cost effective, and easier to use as compared to metal or wooden containers that existed at that time. The DOE Idaho National Engineering and Environmental Laboratory (INEEL), working in conjunction with the plastic industry, tested several types of soft-sided waste packaging systems that meet U.S. Department of Transportation requirements for transport of low specific activity and surface contaminated objects. Since then, soft-sided packaging of various capacities have been used successfully by the decontamination and decommissioning (D&D) projects to package, transport, and dispose D&D wastes throughout the DOE complex. The joint team of experts assembled by the Energy Facility Contractors Group from DOE waste generating sites, DOE and commercial waste disposal facilities, and soft-sided packaging suppliers conducted the review of soft-sided packaging operations and transportation of these packages to the disposal sites. As a result of this evaluation, the team developed several recommendations and best practices to prevent or minimize the recurrences of equipment contamination issues and proper use of soft-sided packaging for transport and disposal of waste.« less

Effects of road traffic noise and the benefit of access to quietness

NASA Astrophysics Data System (ADS)

Öhrström, E.; Skånberg, A.; Svensson, H.; Gidlöf-Gunnarsson, A.

2006-08-01

Socio-acoustic surveys were carried out as part of the Soundscape Support to Health research programme to assess the health effects of various soundscapes in residential areas. The study was designed to test whether having access to a quiet side of one's dwelling enhances opportunities for relaxation and reduces noise annoyance and other adverse health effects related to noise. The dwellings chosen were exposed to sound levels from road traffic ranging from about L=45-68 dB at the most-exposed side. The study involved 956 individuals aged 18-75 years. The results demonstrate that access to quiet indoor and outdoor sections of one's dwelling supports health; it produces a lower degree and extent of annoyance and disturbed daytime relaxation, improves sleep and contributes to physiological and psychological well-being. Having access to a quiet side of one's dwelling reduces disturbances by an average of 30-50% for the various critical effects, and corresponds to a reduction in sound levels of ( LAeq,24h) 5 dB at the most-exposed side. To protect most people (80%) from annoyance and other adverse effects, sound levels from road traffic should not exceed ( LAeq,24h) 60 dB at the most-exposed side, even if there is access to a quiet side of one's dwelling ( LAeq,24h⩽45 dB).

An integrated Riverine Environmental Flow Decision Support System (REFDSS) to evaluate the ecological effects of alternative flow scenarios on river ecosystems

USGS Publications Warehouse

Maloney, Kelly O.; Talbert, Colin B.; Cole, Jeffrey C.; Galbraith, Heather S.; Blakeslee, Carrie J.; Hanson, Leanne; Holmquist-Johnson, Christopher L.

2015-01-01

In regulated rivers, managers must evaluate competing flow release scenarios that attempt to balance both human and natural needs. Meeting these natural flow needs is complex due to the myriad of interacting physical and hydrological factors that affect ecosystems. Tools that synthesize the voluminous scientific data and models on these factors will facilitate management of these systems. Here, we present the Riverine Environmental Flow Decision Support System (REFDSS), a tool that enables evaluation of competing flow scenarios and other variables on instream habitat. We developed a REFDSS for the Upper Delaware River, USA, a system that is regulated by three headwater reservoirs. This version of the REFDSS has the ability to integrate any set of spatially explicit data and synthesizes modeled discharge for three competing management scenarios, flow-specific 2-D hydrodynamic modeled estimates of local hydrologic conditions (e.g., depth, velocity, shear stress, etc.) at a fine pixel-scale (1 m2), and habitat suitability criteria (HSC) for a variety of taxa. It contains all individual model outputs, computationally integrates these data, and outputs the amount of potentially available habitat for a suite of species of interest under each flow release scenario. Users have the flexibility to change the time period of interest and vary the HSC. The REFDSS was developed to enable side-by-side evaluation of different flow management scenarios and their effects on potential habitat availability, allowing managers to make informed decisions on the best flow scenarios. An exercise comparing two alternative flow scenarios to a baseline scenario for several key species is presented. The Upper Delaware REFDSS was robust to minor changes in HSC (± 10 %). The general REFDSS platform was developed as a user-friendly Windows desktop application that was designed to include other potential parameters of interest (e.g., temperature) and for transferability to other riverine systems.

Studies of the molecular effects of a solid support upon lipid membranes and membrane bound proteins

NASA Astrophysics Data System (ADS)

Hartshorn, Christopher M.

Often, membrane/protein systems are studied and/or utilized on solid supports. The underlying substrate in solid supported lipid bilayer assemblies causes large perturbations to the membrane, but the nature of these effects are not well understood. To gain an understanding, these effects were studied on two fronts: the effect upon the membrane by itself, and then the effects upon a membrane/protein system. First, all-atom molecular dynamics (MD) simulations of DLPC, DMPC, POPC, and DEPC on a hydroxylated nanocrystalline alpha-quartz (011) slab revealed a pronounced thinning effect in the lipid bilayers. It was shown that this thinning effect proceeded by one of two mechanisms: the first through a curling of the terminal methyl groups at the interface of the opposing leaflets, and the second through increased interdigitation of the alkyl chains. Also, with the introduction of the solid support, marked asymmetries in a number of structural properties were reported. These asymmetries included (a) the surface area per lipid, (b) the electron densities of the polar head groups, (c) the radial distributions of the choline groups, and (d) the average orientation of water surrounding the membranes. Next, the free energy perturbation method was used to begin calculating the change in free energy (DeltaGbinding) from a Gramicidin monomer to its dimeric state, which were simulated via MD of supported DLPC, DMPC, and DEPC bilayers. The most notable effect was an asymmetry of the calculated free energies relative to the bilayer side closest to the solid support. In all three systems, there was a large difference in free energy between the Gramicidin monomers that were close to the support and the monomers further from the support.

Laterality of proprioception in the orofacial muscles and temporomandibular joint.

PubMed

Frayne, Ellie; Coulson, Susan; Adams, Roger; Croxson, Glen; Waddington, Gordon

2016-12-02

Laterality of function in the orofacial musculature suggests there may be side-to-side asymmetry of proprioceptive acuity in lip movement compared to the temporomandibular joint (TMJ). In the present work, 14 young adults were tested for acuity of lip and TMJ closure movements onto plugs varying from 5 to 8mm without visual feedback. Testing was conducted on both left and right sides, using the same psychophysical task and stimuli. Results showed superior proprioceptive acuity at the lips, with no significant side effect. However, there was side-to-side asymmetry in the correlations between proprioceptive performance for the two anatomical structures, with performance on the right side strongly correlated but not on the left. This is consistent with the need for coordination between structures during chewing. When acuity at different points in the stimulus range was examined, the right side lips were better with small stimuli. Overall, results support enhanced use-specific proprioception. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Stair ascent with an innovative microprocessor-controlled exoprosthetic knee joint.

PubMed

Bellmann, Malte; Schmalz, Thomas; Ludwigs, Eva; Blumentritt, Siegmar

2012-12-01

Climbing stairs can pose a major challenge for above-knee amputees as a result of compromised motor performance and limitations to prosthetic design. A new, innovative microprocessor-controlled prosthetic knee joint, the Genium, incorporates a function that allows an above-knee amputee to climb stairs step over step. To execute this function, a number of different sensors and complex switching algorithms were integrated into the prosthetic knee joint. The function is intuitive for the user. A biomechanical study was conducted to assess objective gait measurements and calculate joint kinematics and kinetics as subjects ascended stairs. Results demonstrated that climbing stairs step over step is more biomechanically efficient for an amputee using the Genium prosthetic knee than the previously possible conventional method where the extended prosthesis is trailed as the amputee executes one or two steps at a time. There is a natural amount of stress on the residual musculoskeletal system, and it has been shown that the healthy contralateral side supports the movements of the amputated side. The mechanical power that the healthy contralateral knee joint needs to generate during the extension phase is also reduced. Similarly, there is near normal loading of the hip joint on the amputated side.

Optimizing the wireless power transfer over MIMO Channels

NASA Astrophysics Data System (ADS)

Wiedmann, Karsten; Weber, Tobias

2017-09-01

In this paper, the optimization of the power transfer over wireless channels having multiple-inputs and multiple-outputs (MIMO) is studied. Therefore, the transmitter, the receiver and the MIMO channel are modeled as multiports. The power transfer efficiency is described by a Rayleigh quotient, which is a function of the channel's scattering parameters and the incident waves from both transmitter and receiver side. This way, the power transfer efficiency can be maximized analytically by solving a generalized eigenvalue problem, which is deduced from the Rayleigh quotient. As a result, the maximum power transfer efficiency achievable over a given MIMO channel is obtained. This maximum can be used as a performance bound in order to benchmark wireless power transfer systems. Furthermore, the optimal operating point which achieves this maximum will be obtained. The optimal operating point will be described by the complex amplitudes of the optimal incident and reflected waves of the MIMO channel. This supports the design of the optimal transmitter and receiver multiports. The proposed method applies for arbitrary MIMO channels, taking transmitter-side and/or receiver-side cross-couplings in both near- and farfield scenarios into consideration. Special cases are briefly discussed in this paper in order to illustrate the method.

Quantifying the variability in stiffness and damping of an automotive vehicle's trim-structure mounts

NASA Astrophysics Data System (ADS)

Abolfathi, Ali; O'Boy, Dan J.; Walsh, Stephen J.; Dowsett, Amy; Fisher, Stephen A.

2016-09-01

Small plastic clips are used in large numbers in automotive vehicles to connect interior trims to vehicle structures. The variability in their properties can contribute to the overall variability in noise and vibration response of the vehicle. The variability arises due to their material and manufacturing tolerances and more importantly due to the boundary condition. To measure their stiffness and damping, a simple experimental rig is used where a mass is supported by the clip which is modelled as a single degree of freedom system. The rig is designed in a way that it simulates the boundary condition as those of the real vehicle. The variability in clip and also due to the boundary condition at the structure side is first examined which is 7% for stiffness and 8% for damping. To simulate the connection of the trim side, a mount is built using a 3D printer. Rattling occurs in the response of the clips with loose connections, however by preloading the mount the effective stiffness increases and the rattling is eliminated. The variability due to the boundary condition at the trim side was as large as 40% for stiffness and 52% for damping.

A web-based computer aided system for liver surgery planning: initial implementation on RayPlus

NASA Astrophysics Data System (ADS)

Luo, Ming; Yuan, Rong; Sun, Zhi; Li, Tianhong; Xie, Qingguo

2016-03-01

At present, computer aided systems for liver surgery design and risk evaluation are widely used in clinical all over the world. However, most systems are local applications that run on high-performance workstations, and the images have to processed offline. Compared with local applications, a web-based system is accessible anywhere and for a range of regardless of relative processing power or operating system. RayPlus (http://rayplus.life.hust.edu.cn), a B/S platform for medical image processing, was developed to give a jump start on web-based medical image processing. In this paper, we implement a computer aided system for liver surgery planning on the architecture of RayPlus. The system consists of a series of processing to CT images including filtering, segmentation, visualization and analyzing. Each processing is packaged into an executable program and runs on the server side. CT images in DICOM format are processed step by to interactive modeling on browser with zero-installation and server-side computing. The system supports users to semi-automatically segment the liver, intrahepatic vessel and tumor from the pre-processed images. Then, surface and volume models are built to analyze the vessel structure and the relative position between adjacent organs. The results show that the initial implementation meets satisfactorily its first-order objectives and provide an accurate 3D delineation of the liver anatomy. Vessel labeling and resection simulation are planned to add in the future. The system is available on Internet at the link mentioned above and an open username for testing is offered.

Chaos in quantum steering in high-dimensional systems

NASA Astrophysics Data System (ADS)

He, Guang Ping

2018-04-01

Quantum steering means that in some bipartite quantum systems the local measurements on one side can determine the state of the other side. Here we show that in high-dimensional systems there exists a specific entangled state which can display a kind of chaos effect when being adopted for steering. That is, a subtle difference in the measurement results on one side can steer the other side into completely orthogonal states. Moreover, by expanding the result to infinite-dimensional systems, we find two sets of states for which, contrary to common belief, even though their density matrices approach being identical, the steering between them is impossible. This property makes them very useful for quantum cryptography.

A hierarchical anatomical classification schema for prediction of phenotypic side effects

PubMed Central

Kanji, Rakesh

2018-01-01

Prediction of adverse drug reactions is an important problem in drug discovery endeavors which can be addressed with data-driven strategies. SIDER is one of the most reliable and frequently used datasets for identification of key features as well as building machine learning models for side effects prediction. The inherently unbalanced nature of this data presents with a difficult multi-label multi-class problem towards prediction of drug side effects. We highlight the intrinsic issue with SIDER data and methodological flaws in relying on performance measures such as AUC while attempting to predict side effects.We argue for the use of metrics that are robust to class imbalance for evaluation of classifiers. Importantly, we present a ‘hierarchical anatomical classification schema’ which aggregates side effects into organs, sub-systems, and systems. With the help of a weighted performance measure, using 5-fold cross-validation we show that this strategy facilitates biologically meaningful side effects prediction at different levels of anatomical hierarchy. By implementing various machine learning classifiers we show that Random Forest model yields best classification accuracy at each level of coarse-graining. The manually curated, hierarchical schema for side effects can also serve as the basis of future studies towards prediction of adverse reactions and identification of key features linked to specific organ systems. Our study provides a strategy for hierarchical classification of side effects rooted in the anatomy and can pave the way for calibrated expert systems for multi-level prediction of side effects. PMID:29494708

A hierarchical anatomical classification schema for prediction of phenotypic side effects.

PubMed

Wadhwa, Somin; Gupta, Aishwarya; Dokania, Shubham; Kanji, Rakesh; Bagler, Ganesh

2018-01-01

Prediction of adverse drug reactions is an important problem in drug discovery endeavors which can be addressed with data-driven strategies. SIDER is one of the most reliable and frequently used datasets for identification of key features as well as building machine learning models for side effects prediction. The inherently unbalanced nature of this data presents with a difficult multi-label multi-class problem towards prediction of drug side effects. We highlight the intrinsic issue with SIDER data and methodological flaws in relying on performance measures such as AUC while attempting to predict side effects.We argue for the use of metrics that are robust to class imbalance for evaluation of classifiers. Importantly, we present a 'hierarchical anatomical classification schema' which aggregates side effects into organs, sub-systems, and systems. With the help of a weighted performance measure, using 5-fold cross-validation we show that this strategy facilitates biologically meaningful side effects prediction at different levels of anatomical hierarchy. By implementing various machine learning classifiers we show that Random Forest model yields best classification accuracy at each level of coarse-graining. The manually curated, hierarchical schema for side effects can also serve as the basis of future studies towards prediction of adverse reactions and identification of key features linked to specific organ systems. Our study provides a strategy for hierarchical classification of side effects rooted in the anatomy and can pave the way for calibrated expert systems for multi-level prediction of side effects.

A sustainable development of a city electrical grid via a non-contractual Demand-Side Management

NASA Astrophysics Data System (ADS)

Samoylenko, Vladislav O.; Pazderin, Andrew V.

2017-06-01

An increasing energy consumption of large cities as well as an extreme high density of city electrical loads leads to the necessity to search for an alternative approaches to city grid development. The ongoing implementation of the energy accounting tariffs with differentiated rates depending upon the market conditions and changing in a short-term perspective, provide the possibility to use it as a financial incentive base of a Demand-Side Management (DSM). Modern hi-technology energy metering and accounting systems with a large number of functions and consumer feedback are supposed to be the good means of DSM. Existing systems of Smart Metering (SM) billing usually provide general information about consumption curve, bills and compared data, but not the advanced statistics about the correspondence of financial and electric parameters. Also, consumer feedback is usually not fully used. So, the efforts to combine the market principle, Smart Metering and a consumer feedback for an active non-contractual load control are essential. The paper presents the rating-based multi-purpose system of mathematical statistics and algorithms of DSM efficiency estimation useful for both the consumers and the energy companies. The estimation is performed by SM Data processing systems. The system is aimed for load peak shaving and load curve smoothing. It is focused primarily on a retail market support. The system contributes to the energy efficiency and a distribution process improvement by the manual management or by the automated Smart Appliances interaction.

Continuous internal counterpulsation as a bridge to recovery in acute and chronic heart failure

PubMed Central

Kontogiannis, Christos D; Malliaras, Konstantinos; Kapelios, Chris J; Mason, Jay W; Nanas, John N

2016-01-01

Cardiac recovery from cardiogenic shock (CS) and end-stage chronic heart failure (HF) remains an often insurmountable therapeutic challenge. The counterpulsation technique exerts numerous beneficial effects on systemic hemodynamics and left ventricular mechanoenergetics, rendering it attractive for promoting myocardial recovery in both acute and chronic HF. Although a recent clinical trial has questioned the clinical effectiveness of short-term hemodynamic support with intra-aortic balloon pump (IABP, the main representative of the counterpulsation technique) in CS complicating myocardial infarction, the issue remains open to further investigation. Moreover, preliminary data suggest that long-term IABP support in patients with end-stage HF is safe and may mediate recovery of left- or/and right-sided cardiac function, facilitating long-term weaning from mechanical support or enabling the application of other permanent, life-saving solutions. The potential of long-term counterpulsation could possibly be enhanced by implementation of novel, fully implantable counterpulsation devices. PMID:27011909

Mobile Phone Based System Opportunities to Home-based Managing of Chemotherapy Side Effects.

PubMed

Davoodi, Somayeh; Mohammadzadeh, Zeinab; Safdari, Reza

2016-06-01

Applying mobile base systems in cancer care especially in chemotherapy management have remarkable growing in recent decades. Because chemotherapy side effects have significant influences on patient's lives, therefore it is necessary to take ways to control them. This research has studied some experiences of using mobile phone based systems to home-based monitor of chemotherapy side effects in cancer. In this literature review study, search was conducted with keywords like cancer, chemotherapy, mobile phone, information technology, side effects and self managing, in Science Direct, Google Scholar and Pub Med databases since 2005. Today, because of the growing trend of the cancer, we need methods and innovations such as information technology to manage and control it. Mobile phone based systems are the solutions that help to provide quick access to monitor chemotherapy side effects for cancer patients at home. Investigated studies demonstrate that using of mobile phones in chemotherapy management have positive results and led to patients and clinicians satisfactions. This study shows that the mobile phone system for home-based monitoring chemotherapy side effects works well. In result, knowledge of cancer self-management and the rate of patient's effective participation in care process improved.

Apparatus for measuring fluid flow

DOEpatents

Smith, Jack E.; Thomas, David G.

1984-01-01

Flow measuring apparatus includes a support loop having strain gages mounted thereon and a drag means which is attached to one end of the support loop and which bends the sides of the support loop and induces strains in the strain gages when a flow stream impacts thereon.

Apparatus for measuring fluid flow

DOEpatents

Smith, J.E.; Thomas, D.G.

Flow measuring apparatus includes a support loop having strain gages mounted thereon and a drag means which is attached to one end of the support loop and which bends the sides of the support loop and induces strains in the strain gages when a flow stream impacts thereon.

Side illuminated optical fiber as a multiplexing element for spectroscopic systems

NASA Astrophysics Data System (ADS)

Egalon, Claudio O.; Matta, Michael P.; Lavezzari, Delbert C.; Insley, Robert Y.; Jaring, Carolyn C.; Quiday, Marie F.

2013-09-01

A new type of colorimeter with multiple channels was demonstrated using a side illuminated optical fiber. When different spots of a properly modified fiber are side illuminated, multiple signals are generated and guided by the waveguide: the essence of multiplexing. This configuration is simple, low cost, does not require a sensitive coating and can analyze several samples along the fiber with a single detector: the most expensive component. Since regular colorimeters use one detector per sample, our new configuration considerably lowers the cost of analyzing multiple samples. This system consists of a fiber mounted over a support, three LEDs, an LED driver, a photo diode and a read-out: to increase the signal, the fiber was tapered. For calibration purposes, six solutions of different concentrations of food dye were prepared, placed inside cuvettes along the fiber length and illuminated by the LEDs. This light passes through the solution, strikes the fiber and is guided to the detector: the darker the solution the lower the signal intensity. Several calibration curves were obtained using different light intensities: it was found that the greater the intensity, the higher the colorimeter sensitivity. This simple capability can be used to easily control the device's sensitivity and its resolution. Although built for three samples only, this device can be modified to accommodate more. With cuvettes measuring 1 cm, it is possible to accommodate one sample per cm of fiber. Also, with minor modifications, this colorimeter can be used for fluorescence, scattering and index of refraction measurements.

Developing effective messages about potable recycled water: The importance of message structure and content

NASA Astrophysics Data System (ADS)

Price, J.; Fielding, K. S.; Gardner, J.; Leviston, Z.; Green, M.

2015-04-01

Community opposition is a barrier to potable recycled water schemes. Effective communication strategies about such schemes are needed. Drawing on social psychological literature, two experimental studies are presented, which explore messages that improve public perceptions of potable recycled water. The Elaboration-Likelihood Model of information processing and attitude change is tested and supported. Study 1 (N = 415) premeasured support for recycled water, and trust in government information at Time 1. Messages varied in complexity and sidedness were presented at Time 2 (3 weeks later), and support and trust were remeasured. Support increased after receiving information, provided that participants received complex rather than simple information. Trust in government was also higher after receiving information. There was tentative evidence of this in response to two-sided messages rather than one-sided messages. Initial attitudes to recycled water moderated responses to information. Those initially neutral or ambivalent responded differently to simple and one-sided messages, compared to participants with positive or negative attitudes. Study 2 (N = 957) tested the effectiveness of information about the low relative risks, and/or benefits of potable recycled water, compared to control groups. Messages about the low risks resulted in higher support when the issue of recycled water was relevant. Messages about benefits resulted in higher perceived issue relevance, but did not translate into greater support. The results highlight the importance of understanding people's motivation to process information, and need to tailor communication to match attitudes and stage of recycled water schemes' development.

[Necrotizing fasciitis in head and neck area].

PubMed

Sántha, Beáta; Sári, Katalin; Fülep, Zoltán; Patyi, Márta; Oberna, Ferenc

2017-03-01

Necrotizing fasciitis is a fulminant infection of the deeper layers of skin and subcutaneous tissues characterized by progressive soft tissue necrosis and high mortality. It rarely occurs in the head and neck area. The clinical picture includes non-specific but typical local and systemic symptoms. The treatment is a complex, multidisciplinary task which includes radical surgical exploration, debridement and drainage, empirically started and then targeted intravenous antibiotics and supportive therapy. Authors report a case of necrotizing fasciitis localized on the right side of the face which caused multi-organ failure and phlegmone of the neck.

Energy harvesting from torsions of patterned piezoelectrics

NASA Astrophysics Data System (ADS)

Cha, Youngsu; You, Hangil

2018-03-01

In this paper, we investigate the feasibility of energy harvesting from the torsions using a piezoelectric beam. The piezoelectric beam is partially patterned and is tested in an experimental setup to force pure torsional deformation. In particular, the beam consists of two identical piezoelectric parts attached on one side of a supporting substrate. We propose a model for the energy harvesting system through the equations for a slender composite beam with the physical properties and the electromechanical coupling equations of the piezoelectric material. The theoretical predictions are validated by the comparison with the experimental results.

Thermal Expansion of Metal Matrix Composites.

DTIC Science & Technology

1981-08-01

mirrors by M, for the right-hand side, the interferometer optical path length difference is OPLD I = B1S 1 - BIM 6 (20) Similarly, OPLD2 2 B M5 - S2M4...resultant optics separation) available and by the amount of heat flow the system can tolerate. Thin horizontal Invar or Zerodur support rods have proved...Aluminized end faces, polished < X/5, are preferable to altern-te mounted mirrors 18 of X/2 to X/5 and coated with a few hundred angstroms of vapor-deposited

Textile technology development

NASA Technical Reports Server (NTRS)

Shah, Bharat M.

1995-01-01

The objectives of this report were to evaluate and select resin systems for Resin Transfer Molding (RTM) and Powder Towpreg Material, to develop and evaluate advanced textile processes by comparing 2-D and 3-D braiding for fuselage frame applications and develop window belt and side panel structural design concepts, to evaluate textile material properties, and to develop low cost manufacturing and tooling processes for the automated manufacturing of fuselage primary structures. This research was in support of the NASA and Langley Research Center (LaRc) Advanced Composite Structural Concepts and Materials Technologies for Primary Aircraft Structures program.

CAD-design, stress analysis and in vitro evaluation of three leaflet blood-pump valves.

PubMed

Knierbein, B; Rosarius, N; Unger, A; Reul, H; Rau, G

1992-07-01

The computer-supported development of valves for cardiac-assist devices or artificial hearts is shown in relation to plastic technology. A CAD-system is used for the design development, whereas the dimensioning of the critical and highly stressed membranes is examined by FEM-analyses. Economic manufacture is permitted by the combined thermoforming-dip moulding technique; the blood-side components are made from biocompatible polyurethane to minimize blood damage. The first long-term results in the test set-up are compared to the FEM results.

Adjuvant endocrine therapy after breast cancer: a qualitative study of factors associated with adherence

PubMed Central

Boulton, Mary; Fenlon, Debbie; Hulbert-Williams, Nick J; Walter, Fiona M; Donnelly, Peter; Lavery, Bernadette A; Morgan, Adrienne; Morris, Carolyn; Watson, Eila K

2018-01-01

Introduction Despite evidence of the efficacy of adjuvant endocrine therapy (AET) in reducing the risk of recurrence and mortality after treatment for primary breast cancer, adherence to AET is suboptimal. This study aimed to explore factors that influence adherence and nonadherence to AET following breast cancer to inform the development of supportive interventions. Methods Interviews were conducted with 32 women who had been prescribed AET, 2–4 years following their diagnosis of breast cancer. Both adherers (n=19) and nonadherers (n=13) were recruited. The analysis was conducted using the Framework approach. Results Factors associated with adherence were as follows: managing side effects including information and advice on side effects and taking control of side effects, supportive relationships, and personal influences. Factors associated with nonadherence were as follows: burden of side effects, feeling unsupported, concerns about long-term AET use, regaining normality, including valuing the quality of life over length of life, and risk perception. Conclusion Provision of timely information to prepare women for the potential side effects of AET and education on medication management strategies are needed, including provision of timely and accurate information on the efficacy of AET in reducing breast cancer recurrence and on potential side effects and ways to manage these should they arise. Trust in the doctor–patient relationship and clear patient pathways for bothersome side effects and concerns with AET are important. Training and education on AET for GPs should be considered alongside novel care pathways such as primary care nurse cancer care review and community pharmacist follow-up. PMID:29497284

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wicks, Christopher Donald; Madin, Mark Michael

A cam carrier assembly includes a cylinder head having valves and a camshaft having lobes. A cam carrier has a first side coupled with the cylinder head engaging around the valves and a second side with bearing surfaces supporting the camshaft. A series of apertures extend between the first and second sides for the lobes to interface with the valves. The cam carrier is made of carbon fiber composite insulating the camshaft from the cylinder head and providing substantial weight reduction to an upper section of an associated engine.

Nuclear reactor construction with bottom supported reactor vessel

DOEpatents

Sharbaugh, John E.

1987-01-01

An improved liquid metal nuclear reactor construction has a reactor core and a generally cylindrical reactor vessel for holding a large pool of low pressure liquid metal coolant and housing the core within the pool. The reactor vessel has an open top end, a closed flat bottom end wall and a continuous cylindrical closed side wall interconnecting the top end and bottom end wall. The reactor also has a generally cylindrical concrete containment structure surrounding the reactor vessel and being formed by a cylindrical side wall spaced outwardly from the reactor vessel side wall and a flat base mat spaced below the reactor vessel bottom end wall. A central support pedestal is anchored to the containment structure base mat and extends upwardly therefrom to the reactor vessel and upwardly therefrom to the reactor core so as to support the bottom end wall of the reactor vessel and the lower end of the reactor core in spaced apart relationship above the containment structure base mat. Also, an annular reinforced support structure is disposed in the reactor vessel on the bottom end wall thereof and extends about the lower end of the core so as to support the periphery thereof. In addition, an annular support ring having a plurality of inward radially extending linear members is disposed between the containment structure base mat and the bottom end of the reactor vessel wall and is connected to and supports the reactor vessel at its bottom end on the containment structure base mat so as to allow the reactor vessel to expand radially but substantially prevent any lateral motions that might be imposed by the occurrence of a seismic event. The reactor construction also includes a bed of insulating material in sand-like granular form, preferably being high density magnesium oxide particles, disposed between the containment structure base mat and the bottom end wall of the reactor vessel and uniformly supporting the reactor vessel at its bottom end wall on the containment structure base mat so as to insulate the reactor vessel bottom end wall from the containment structure base mat and allow the reactor vessel bottom end wall to freely expand as it heats up while providing continuous support thereof. Further, a deck is supported upon the side wall of the containment structure above the top open end of the reactor vessel, and a plurality of serially connected extendible and retractable annular bellows extend between the deck and the top open end of the reactor vessel and flexibly and sealably interconnect the reactor vessel at its top end to the deck. An annular guide ring is disposed on the containment structure and extends between its side wall and the top open end of the reactor vessel for providing lateral support of the reactor vessel top open end by limiting imposition of lateral loads on the annular bellows by the occurrence of a lateral seismic event.

Religious Involvement, Social Support, and Health Among African-American Women on the East Side of Detroit

PubMed Central

Van Olphen, Juliana; Schulz, Amy; Israel, Barbara; Chatters, Linda; Klem, Laura; Parker, Edith; Williams, David

2003-01-01

BACKGROUND A significant body of research suggests that religious involvement is related to better mental and physical health. Religion or spirituality was identified as an important health protective factor by women participating in the East Side Village Health Worker Partnership (ESVHWP), a community-based participatory research initiative on Detroit's east side. However, relatively little research to date has examined the mechanisms through which religion may exert a positive effect on health. OBJECTIVE The research presented here examines the direct effects of different forms of religious involvement on health, and the mediating effects of social support received in the church as a potential mechanism that may account for observed relationships between church attendance and health. DESIGN This study involved a random sample household survey of 679 African-American women living on the east side of Detroit, conducted as part of the ESVHWP. MAIN RESULTS Results of multivariate analyses show that respondents who pray less often report a greater number of depressive symptoms, and that faith, as an important source of strength in one's daily life, is positively associated with chronic conditions such as asthma or arthritis. Tests of the mediating effect of social support in the church indicated that social support received from church members mediates the positive relationship between church attendance and specific indicators of health. CONCLUSIONS These findings are consistent with the hypothesis that one of the major ways religious involvement benefits health is through expanding an individual's social connections. The implications of these findings for research and practice are discussed. PMID:12848838

Electronic Structure Theory Study of the Microsolvated F(-)(H2O) + CH3I SN2 Reaction.

PubMed

Zhang, Jiaxu; Yang, Li; Sheng, Li

2016-05-26

The potential energy profile of microhydrated fluorine ion reaction with methyl iodine has been characterized by extensive electronic structure calculations. Both hydrogen-bonded F(-)(H2O)---HCH2I and ion-dipole F(-)(H2O)---CH3I complexes are formed for the reaction entrance and the PES in vicinity of these complexes is very flat, which may have important implications for the reaction dynamics. The water molecule remains on the fluorine side until the reactive system goes to the SN2 saddle point. It can easily move to the iodine side with little barrier, but in a nonsynchronous reaction path after the dynamical bottleneck to the reaction, which supports the previous prediction for microsolvated SN2 systems. The influence of solvating water molecule on the reaction mechanism is probed by comparing with the influence of the nonsolvated analogue and other microsolvated SN2 systems. Taking the CCSD(T) single-point calculations based on MP2-optimized geometries as benchmark, the DFT functionals B97-1 and B3LYP are found to better characterize the potential energy profile for the title reaction and are recommended as the preferred methods for the direct dynamics simulations to uncover the dynamic behaviors.

Flight Systems Integration and Test

NASA Technical Reports Server (NTRS)

Wright, Michael R.

2011-01-01

Topics to be Covered in this presentation are: (1) Integration and Test (I&T) Planning (2) Integration and Test Flows (3) Overview of Typical Mission I&T (4) Supporting Elements (5) Lessons-Learned and Helpful Hints (6) I&T Mishaps and Failures (7) The Lighter Side of I&T and (8) Small-Group Activity. This presentation highlights a typical NASA "in-house" I&T program (1) For flight systems that are developed by NASA at a space flight center (like GSFC) (2) Requirements well-defined: qualification/acceptance, documentation, configuration management. (3) Factors: precedents, human flight, risk-aversion ("failure-phobia"), taxpayer dollars, jobs and (4) Some differences among NASA centers, but generally a resource-intensive process

STS-112 crew during Crew Equipment Interface Test

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. -- During a Crew Equipment Interface Test, STS-112 Commander Jeffrey Ashby checks out the windshield on Atlantis, the designated orbiter for the mission. STS-112 is the 15th assembly flight to the International Space Station and will be ferrying the S1 Integrated Truss Structure. The S1 truss is the first starboard (right-side) truss segment, whose main job is providing structural support for the radiator panels that cool the Space Station's complex power system. The S1 truss segment also will house communications systems, external experiment positions and other subsystems. The S1 truss will be attached to the S0 truss. STS-112 is currently scheduled for launch Aug. 22, 2002.

Pad 39B Flame Trench Brick Work

NASA Image and Video Library

2016-10-26

Progress continues on the new flame trench at Launch Pad 39B at NASA's Kennedy Space Center in Florida. Construction workers with J.P. Donovan of Rockledge, Florida, are on an elevated work stand to install new heat-resistant bricks on the north side of the flame trench. The Pad B flame trench is being refurbished to support the launch of NASA’s Space Launch System rocket. The Ground Systems Development and Operations (GSDO) Program at Kennedy is helping transform the space center into a multi-user spaceport and prepare for Exploration Mission 1, deep space missions, and NASA's Journey to Mars. For more information about GSDO, visit: http://www.nasa.gov/groundsystems.

Final Flame Trench Brick Installation at Launch Pad 39B

NASA Image and Video Library

2017-05-09

The final brick was installed on the north side of the flame trench at Launch Complex 39B at NASA’s Kennedy Space Center in Florida. The walls of the flame trench are being upgraded to withstand the intense heat and fire at launch of NASA's Space Launch System rocket with Orion atop. About 96,000 heat-resistant bricks, in three different sizes, were secured to the walls using bonding mortar in combination with adhesive anchors. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to Pad 39B to support the launch of the SLS and Orion spacecraft for Exploration Mission-1 and NASA’s journey to Mars.

Final Flame Trench Brick Installation at Launch Pad 39B

NASA Image and Video Library

2017-05-09

Construction workers sign the final bricks after they were installed on the north side of the flame trench at Launch Complex 39B at NASA’s Kennedy Space Center in Florida. The walls of the flame trench are being upgraded to withstand the intense heat and fire at launch of NASA's Space Launch System rocket with Orion atop. About 96,000 heat-resistant bricks, in three different sizes, were secured to the walls using bonding mortar in combination with adhesive anchors. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to Pad 39B to support the launch of the SLS and Orion spacecraft for Exploration Mission-1 and NASA’s journey to Mars.

Final Flame Trench Brick Installation at Launch Pad 39B

NASA Image and Video Library

2017-05-09

A construction worker installs one of the final bricks on the north side of the flame trench at Launch Complex 39B at NASA's Kennedy Space Center in Florida. The walls of the flame trench are being upgraded to withstand the intense heat and fire at launch of NASA's Space Launch System rocket with Orion atop. About 96,000 heat-resistant bricks, in three different sizes, were secured to the walls using bonding mortar in combination with adhesive anchors. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to Pad 39B to support the launch of the SLS and Orion spacecraft for Exploration Mission-1 and NASA’s journey to Mars.

Final Flame Trench Brick Installation at Launch Pad 39B

NASA Image and Video Library

2017-05-09

A view looking up from the north side of the flame trench beneath the pad at Launch Complex 39B at NASA's Kennedy Space Center in Florida. The walls of the flame trench are being upgraded to withstand the intense heat and fire at launch of NASA's Space Launch System rocket with Orion atop. About 96,000 heat-resistant bricks, in three different sizes, were secured to the walls using bonding mortar in combination with adhesive anchors. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to Pad 39B to support the launch of the SLS and Orion spacecraft for Exploration Mission-1 and NASA’s journey to Mars.

Final Flame Trench Brick Installation at Launch Pad 39B

NASA Image and Video Library

2017-05-09

Preparations are underway to install the final brick on the north side of the flame trench at Launch Complex 39B at NASA's Kennedy Space Center in Florida. The walls of the flame trench are being upgraded to withstand the intense heat and fire at launch of NASA's Space Launch System rocket with Orion atop. About 96,000 heat-resistant bricks, in three different sizes, were secured to the walls using bonding mortar in combination with adhesive anchors. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to Pad 39B to support the launch of the SLS and Orion spacecraft for Exploration Mission-1 and NASA’s journey to Mars.

Final Flame Trench Brick Installation at Launch Pad 39B

NASA Image and Video Library

2017-05-09

A construction worker installs the final brick on the north side of the flame trench at Launch Complex 39B at NASA's Kennedy Space Center in Florida. The walls of the flame trench are being upgraded to withstand the intense heat and fire at launch of NASA's Space Launch System rocket with Orion atop. About 96,000 heat-resistant bricks, in three different sizes, were secured to the walls using bonding mortar in combination with adhesive anchors. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to Pad 39B to support the launch of the SLS and Orion spacecraft for Exploration Mission-1 and NASA’s journey to Mars.

STS-112 crew during Crew Equipment Interface Test

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. -- During a Crew Equipment Interface Test, STS-112 Pilot Pamela Melroy checks out the windshield on Atlantis, the designated orbiter for the mission. STS-112 is the 15th assembly flight to the International Space Station and will be ferrying the S1 Integrated Truss Structure. The S1 truss is the first starboard (right-side) truss segment, whose main job is providing structural support for the radiator panels that cool the Space Station's complex power system. The S1 truss segment also will house communications systems, external experiment positions and other subsystems. The S1 truss will be attached to the S0 truss. STS-112 is currently scheduled for launch Aug. 22, 2002.

Final Flame Trench Brick Installation at Launch Pad 39B

NASA Image and Video Library

2017-05-09

Construction workers install the final bricks on the north side of the flame trench at Launch Complex 39B at NASA's Kennedy Space Center in Florida. The walls of the flame trench are being upgraded to withstand the intense heat and fire at launch of NASA's Space Launch System rocket with Orion atop. About 96,000 heat-resistant bricks, in three different sizes, were secured to the walls using bonding mortar in combination with adhesive anchors. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to Pad 39B to support the launch of the SLS and Orion spacecraft for Exploration Mission-1 and NASA’s journey to Mars.

KSC-99pp1191

NASA Image and Video Library

1999-10-07

KENNEDY SPACE CENTER, FLA. -- A KSC transporter moves the Guppy cargo carrier encasing the S1 truss into the Operations and Checkout Building. Manufactured by the Boeing Co. in Huntington Beach, Calif., this component of the International Space Station is the first starboard (right-side) truss segment, whose main job is providing structural support for the orbiting research facility's radiator panels that cool the Space Station's complex power system. The S1 truss segment also will house communications systems, external experiment positions and other subsystems. Primarily constructed of aluminum, the truss segment is 45 feet long, 15 feet wide and 6 feet tall. When fully outfitted, it will weigh 31,137 pounds. The truss is slated for flight in 2001

DeltaPhage—a novel helper phage for high-valence pIX phagemid display

PubMed Central

Nilssen, Nicolay R.; Frigstad, Terje; Pollmann, Sylvie; Roos, Norbert; Bogen, Bjarne; Sandlie, Inger; Løset, Geir Å.

2012-01-01

Phage display has been instrumental in discovery of novel binding peptides and folded domains for the past two decades. We recently reported a novel pIX phagemid display system that is characterized by a strong preference for phagemid packaging combined with low display levels, two key features that support highly efficient affinity selection. However, high diversity in selected repertoires are intimately coupled to high display levels during initial selection rounds. To incorporate this additional feature into the pIX display system, we have developed a novel helper phage termed DeltaPhage that allows for high-valence display on pIX. This was obtained by inserting two amber mutations close to the pIX start codon, but after the pVII translational stop, conditionally inactivating the helper phage encoded pIX. Until now, the general notion has been that display on pIX is dependent on wild-type complementation, making high-valence display unachievable. However, we found that DeltaPhage does facilitate high-valence pIX display when used with a non-suppressor host. Here, we report a side-by-side comparison with pIII display, and we find that this novel helper phage complements existing pIX phagemid display systems to allow both low and high-valence display, making pIX display a complete and efficient alternative to existing pIII phagemid display systems. PMID:22539265

DeltaPhage--a novel helper phage for high-valence pIX phagemid display.

PubMed

Nilssen, Nicolay R; Frigstad, Terje; Pollmann, Sylvie; Roos, Norbert; Bogen, Bjarne; Sandlie, Inger; Løset, Geir Å

2012-09-01

Phage display has been instrumental in discovery of novel binding peptides and folded domains for the past two decades. We recently reported a novel pIX phagemid display system that is characterized by a strong preference for phagemid packaging combined with low display levels, two key features that support highly efficient affinity selection. However, high diversity in selected repertoires are intimately coupled to high display levels during initial selection rounds. To incorporate this additional feature into the pIX display system, we have developed a novel helper phage termed DeltaPhage that allows for high-valence display on pIX. This was obtained by inserting two amber mutations close to the pIX start codon, but after the pVII translational stop, conditionally inactivating the helper phage encoded pIX. Until now, the general notion has been that display on pIX is dependent on wild-type complementation, making high-valence display unachievable. However, we found that DeltaPhage does facilitate high-valence pIX display when used with a non-suppressor host. Here, we report a side-by-side comparison with pIII display, and we find that this novel helper phage complements existing pIX phagemid display systems to allow both low and high-valence display, making pIX display a complete and efficient alternative to existing pIII phagemid display systems.

Axially shaped channel and integral flow trippers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crowther, R.L.; Johansson, E.B.; Matzner, B.

1988-06-07

A fuel assembly is described comprising fuel rods positioned in spaced array by upper and lower tie-plates, an open ended flow channel surrounding the array for conducting coolant upward between a lower support plate having coolant communicated thereto to an upper support grid having a steam/water outlet communicated thereto. The flow channel surrounds the array for conducting coolant about the fuel rods. The open ended channel has a polygon shaped cross section with the channel constituting a closed conduit with flat side sections connected at corners to form the enclosed conduit; means separate from the channel for connecting the uppermore » and lower tie-plates together and maintaining the fuel rods in spaced array independent of the flow channel. The improvement in the flow channel comprises tapered side walls. The tapered side walls extend from an average thick cross section adjacent the lower support plate to an average thin cross section adjacent the upper core grid whereby the channel is reduced in thickness adjacent the upper core grid to correspond with the reduced pressure adjacent the upper core grid.« less

Axially shaped channel and integral flow trippers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crowther, R.L. Jr.; Johansson, E.B.; Matzner, B.

1992-02-11

This patent describes a fuel assembly. It comprises: fuel rods positioned in spaced array by upper and lower tie-plates, and open ended flow channel surrounding the array for conducting coolant upward between a lower support plate having coolant communicated thereto to an upper support grid having a steam/water outlet communicated thereto. The flow channel surrounding the array for conducting coolant about the fuel rods; the open ended channel having a polygon shaped cross section with the channel constituting a closed conduit with flat side sections connected at corners to form the enclosed conduit; means separate from the channel for connectingmore » the upper and lower tie-plates together and maintaining the fuel rods in spaced array independent of the flow channel, the improvement in the flow channel comprising tapered side walls, the tapered side walls extending from an average thick cross section adjacent the lower support plate to an average thin cross section adjacent the upper core grid whereby the channel is reduced in thickness adjacent the upper core grid to correspond with the reduced pressure adjacent the upper core grid.« less

Memory for Medication Side Effects in Younger and Older Adults: The Role of Subjective and Objective Importance

PubMed Central

Friedman, Michael C.; McGillivray, Shannon; Murayama, Kou; Castel, Alan D.

2014-01-01

Older adults often experience memory impairments, but can sometimes use selective processing and schematic support to remember important information. The current experiments investigate to what degree younger and healthy older adults remember medication side effects that were subjectively or objectively important to remember. Participants studied a list of common side effects, and rated how negative these effects were if they were to experience them, and were then given a free recall test. In Experiment 1, the severity of the side effects ranged from mild (e.g., itching) to severe (e.g., stroke), and in Experiment 2, certain side effects were indicated as critical to remember (i.e., “contact your doctor if you experience this”). There were no age differences in terms of free recall of the side effects, and older adults remembered more severe side effects relative to mild effects. However, older adults were less likely to recognize critical side effects on a later recognition test, relative to younger adults. The findings suggest that older adults can selectively remember medication side effects, but have difficulty identifying familiar but potentially critical side effects, and this has implications for monitoring medication use in older age. PMID:25331278

78 FR 64164 - Airworthiness Directives; the Boeing Company Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-28

.... ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for certain the Boeing... frame, forward and aft inner chords, floor support, bulkhead upper web on the upper left and right side of the bulkhead, and the bulkhead lower web on the lower left side of the bulkhead and repair if...

Mechanical membrane for the separation of a paramagnetic constituent from a fluid

DOEpatents

Maurice, David

2017-05-02

The disclosure provides an apparatus and method for the separation of a paramagnetic component from a mixture using a mechanical membrane apparatus. The mechanical membrane comprises a supporting material having a plurality of pores where each pore is surrounded by a plurality of magnetic regions. The magnetic regions augment a magnetic field on one side of the supporting material while mitigating the field to near zero on the opposite side. In operation, a flow of fluid such as air comprising a paramagnetic component such as O.sub.2 is directed toward the mechanical membrane, and the paramagnetic component is typically attracted toward a magnetic field surrounding a pore while dimagnetic components such as N.sub.2 are generally repelled. As some portion of the fluid passes through the plurality of magnetic apertures to the opposite side of the mechanical membrane, the mechanical membrane generates a fluid enriched in the paramagnetic component. Alternately, the magnetic field may act to repel the paramagnetic component while diamagnetic components such as N.sub.2 are generally unaffected and pass to the opposite side of the mechanical membrane.

Mechanical spin bearings

NASA Technical Reports Server (NTRS)

Vranish, John M. (Inventor)

1998-01-01

A spin bearing assembly including, a pair of mutually opposing complementary bearing support members having mutually spaced apart bearing support surfaces which may be, for example, bearing races and a set of spin bearings located therebetween. Each spin bearing includes a pair of end faces, a central rotational axis passing through the end faces, a waist region substantially mid-way between the end faces and having a first thickness dimension, and discrete side surface regions located between the waist region and the end faces and having a second thickness dimension different from the first thickness dimension of the waist region and wherein the side surface regions further have respective curvilinear contact surfaces adapted to provide a plurality of bearing contact points on the bearing support members.

Transforming Agricultural Water Management in Support of Ecosystem Restoration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanlon, Edward; Capece, John

Threats to ecosystems are not local; they have to be handled with the global view in mind. Eliminating Florida farms, in order to meet its environmental goals, would simply move the needed agricultural production overseas, where environmentally less sensitive approaches are often used, thus yielding no net ecological benefit. South Florida is uniquely positioned to lead in the creation of sustainable agricultural systems, given its population, technology, and environmental restoration imperative. Florida should therefore aggressively focus on developing sustainable systems that deliver both agricultural production and environmental services. This presentation introduces a new farming concept of dealing with Florida’s agriculturalmore » land issues. The state purchases large land areas in order to manage the land easily and with ecosystem services in mind. The proposed new farming concept is an alternative to the current “two sides of the ditch” model, in which on one side are yield-maximizing, input-intensive, commodity price-dependent farms, while on the other side are publicly-financed, nutrient-removing treatment areas and water reservoirs trying to mitigate the externalized costs of food production systems and other human-induced problems. The proposed approach is rental of the land back to agriculture during the restoration transition period in order to increase water storage (allowing for greater water flow-through and/or water storage on farms), preventing issues such as nutrients removal, using flood-tolerant crops and reducing soil subsidence. Since the proposed approach is still being developed, there exist various unknown variables and considerations. However, working towards a long-term sustainable scenario needs to be the way ahead, as the threats are global and balancing the environment and agriculture is a serious global challenge.« less

A Functional Approach to Hyperspectral Image Analysis in the Cloud

NASA Astrophysics Data System (ADS)

Wilson, A.; Lindholm, D. M.; Coddington, O.; Pilewskie, P.

2017-12-01

Hyperspectral image volumes are very large. A hyperspectral image analysis (HIA) may use 100TB of data, a huge barrier to their use. Hylatis is a new NASA project to create a toolset for HIA. Through web notebook and cloud technology, Hylatis will provide a more interactive experience for HIA by defining and implementing concepts and operations for HIA, identified and vetted by subject matter experts, and callable within a general purpose language, particularly Python. Hylatis leverages LaTiS, a data access framework developed at LASP. With an OPeNDAP compliant interface plus additional server side capabilities, the LaTiS API provides a uniform interface to virtually any data source, and has been applied to various storage systems, including: file systems, databases, remote servers, and in various domains including: space science, systems administration and stock quotes. In the LaTiS architecture, data `adapters' read data into a data model, where server-side computations occur. Data `writers' write data from the data model into the desired format. The Hylatis difference is the data model. In LaTiS, data are represented as mathematical functions of independent and dependent variables. Domain semantics are not present at this level, but are instead present in higher software layers. The benefit of a domain agnostic, mathematical representation is having the power of math, particularly functional algebra, unconstrained by domain semantics. This agnosticism supports reusable server side functionality applicable in any domain, such as statistical, filtering, or projection operations. Algorithms to aggregate or fuse data can be simpler because domain semantics are separated from the math. Hylatis will map the functional model onto the Spark relational interface, thereby adding a functional interface to that big data engine.This presentation will discuss Hylatis goals, strategies, and current state.

A comparison of the effects of visual deprivation and regular body weight support treadmill training on improving over-ground walking of stroke patients: a multiple baseline single subject design.

PubMed

Kim, Jeong-Soo; Kang, Sun-Young; Jeon, Hye-Seon

2015-01-01

The body-weight-support treadmill (BWST) is commonly used for gait rehabilitation, but other forms of BWST are in development, such as visual-deprivation BWST (VDBWST). In this study, we compare the effect of VDBWST training and conventional BWST training on spatiotemporal gait parameters for three individuals who had hemiparetic strokes. We used a single-subject experimental design, alternating multiple baselines across the individuals. We recruited three individuals with hemiparesis from stroke; two on the left side and one on the right. For the main outcome measures we assessed spatiotemporal gait parameters using GAITRite, including: gait velocity; cadence; step time of the affected side (STA); step time of the non-affected side (STN); step length of the affected side (SLA); step length of the non-affected side (SLN); step-time asymmetry (ST-asymmetry); and step-length asymmetry (SL-asymmetry). Gait velocity, cadence, SLA, and SLN increased from baseline after both interventions, but STA, ST-asymmetry, and SL-asymmetry decreased from the baseline after the interventions. The VDBWST was significantly more effective than the BWST for increasing gait velocity and cadence and for decreasing ST-asymmetry. VDBWST is more effective than BWST for improving gait performance during the rehabilitation for ground walking.

Temporary implant-supported prosthesis for immediate loading according to a chair-side concept: technical note and results from 37 consecutive cases.

PubMed

Ostman, Pär-Olov; Hellman, Mats; Sennerby, Lars; Wennerberg, Ann

2008-05-01

During the last years, focus has been paid to implant treatment using immediate function protocols, and different approaches to provide patients with temporary constructions have been presented. Most of these techniques involve dental technicians producing the temporary construction, for example, rebuilding existing dentures, acrylic bridges, etc. The purpose of this prospective clinical study was to evaluate the clinical outcome of a chair-side technique of a cost-effective temporary prosthesis. Fixture survival rate and risk of temporary bridge failure were analyzed. Thirty-seven partially or totally edentate patients (18 female and 19 male; mean age: 66.7 years) treated with chair-side manufactured temporary restorations (QuickBridge, BIOMET 3i, Palm Beach, Fl, USA) for immediate loading have been evaluated. The prostheses extended from two unit bridges supported by two implants to full-arch construction supported by six implants. The temporary prostheses were monitored from the day of surgery and delivery to the time of replacement with a permanent prosthetic construction 3 to 6 months later. No implants were lost during the observation time. One (3%) temporary prosthesis fractured and additional two (6%) loosened during the follow-up time. The study indicated that the tested chair-side concept for manufacturing of temporary prosthesis for immediate loading of dental implants is a viable approach.

Systemic hypertension and the right-sided cardiovascular system: a review of the available evidence.

PubMed

Pedrinelli, Roberto; Dell'Omo, Giulia; Talini, Enrica; Canale, Maria Laura; Di Bello, Vitantonio

2009-02-01

Abnormal vasoconstriction of the lesser circulation characterizes a subset of patients with essential hypertension, a possible effect of mechanisms, such as enhanced sympathetic tone, increased delivery of blood-borne vasoconstrictor substances or abnormal local release of vasoactive factors, acting on both sides of the circulation or to backward transmission of increased pressure due to stiffer left ventricles with more advanced diastolic dysfunction. Elevated systemic pressure also associates with thickening of the right ventricle, a central element of the low-pressure system. Right ventricular remodelling develops in parallel with a similar process occurring at the left side, likely as a result of ventricular interdependence under the influence of trophic factors targeting both ventricles, though other mechanisms, including increased pulmonary afterload, may also be operative. By and large independent of the extent of structural remodelling of both ventricles, systemic hypertension also conditions an impaired filling rate of the right ventricle that accompanies a similar phenomenon at the left side. Thus, quite in contrast with the common and simplistic assumption of a separate behaviour of the two ventricles, the right-sided cardiovascular system is not immune to the effect of systemic hypertension, a concept whose clinical and pathophysiological implications require further studies.

Stability of hydrogenated graphene: a first-principles study

DOE PAGES

Yi, Ding; Yang, Liu; Xie, Shijie; ...

2015-02-10

In order to explain the disagreement between present theoretical and experimental investigations on the stability of hydrogenated graphene, we have systematically studied hydrogenated graphene with different configurations from the consideration of single-side and double-side adsorption using first-principles calculations. Both binding energy and formation energy are calculated to characterize the stability of the system. It is found that single-side hydrogenated graphene is always unstable. However, for double-side hydrogenation, some configurations are stable due to the increased carbon–carbon sp 3 hybridization compared to single-side hydrogenation. Furthermore, it is found that the system is energetically favorable when an equal number of hydrogen atomsmore » are adsorbed on each side of the graphene.« less

Anthropometric considerations for a 4-axis side-arm flight controller

NASA Technical Reports Server (NTRS)

Debellis, W. B.

1986-01-01

A data base on multiaxis side-arm flight controls was generated. The rapid advances in fly-by-light technology, automatic stability systems, and onboard computers have combined to create flexible flight control systems which could reduce the workload imposed on the operator by complex new equipment. This side-arm flight controller combines four controls into one unit and should simplify the pilot's task. However, the use of a multiaxis side-arm flight controller without complete cockpit integration may tend to increase the pilot's workload.

Value of transperineal ultrasound on the observation of paravaginal support.

PubMed

Dou, Chaoran; Li, Qin; Ying, Tao; Shui, Wen; Yan, Yulin; Luo, Yijia; Wang, Xia

2018-04-01

To explore the feasibility of three-dimensional (3D) transperineal ultrasound on the observation of paravaginal support in nulliparous and postpartum women. Volume datasets were acquired in 50 nulliparous and 100 postpartum women using 3D transperineal ultrasound. Paravaginal supports were observed by studying the vaginal cross-sectional morphology. The extent of paravaginal support in specific level were evaluated by counting out at a 2 mm interval in tomographic ultrasound imaging mode in all subjects. The Mann-Whitney U test were applied to establish comparisons between the two groups. Three representative manifestations of vaginal cross-sectional morphology corresponding to different paravaginal support were presented from the dorsal side to the caudal side, both in nulliparous women and postpartum women. The extent of paravaginal support in middle vagina was 11 slices (range 9-12) in nulliparous women and 7 slices (range 4-10) in postpartum women (P < 0.05). This pilot study confirmed that it was feasible to indirectly study paravaginal support by observing the vaginal cross-sectional morphology using 3D transperineal ultrasound.

Modeling of coupling mechanism of wireless power transfer system and vibration phenomenon of receiver-coil in three-coil system

NASA Astrophysics Data System (ADS)

Liu, Suqi; Tan, Jianping; Wen, Xue

2017-11-01

Wireless power transfer (WPT) via coupled magnetic resonances has become a focus recently, but the mechanisms responsible for such work are uncertain. We found that WPT system is a self-organization system by utilizing self-organization theory to judge. Firstly, the circuit model was established and transfer characteristic of a system was researched by utilizing circuit theories. Thus, with the introduction of entropy variable S, the energy equation of state can be established from the energy of the transmitter side and the energy of the receiver side. According to the energy equation of state, this paper obtains two equations when the reactance of the transmitter side and the receiver side equate to zero respectively. The vibration phenomenon of the receiver-coil in a three-coil WPT system was predicted and explained. Our findings illuminate the unusual self-organization in the WPT system and explain the vibration phenomenon of the receiver-coil in a three-coil WPT system.

Space ultra-vacuum facility and method of operation

NASA Technical Reports Server (NTRS)

Naumann, Robert J. (Inventor)

1988-01-01

A wake shield space processing facility (10) for maintaining ultra-high levels of vacuum is described. The wake shield (12) is a truncated hemispherical section having a convex side (14) and a concave side (24). Material samples (68) to be processed are located on the convex side of the shield, which faces in the wake direction in operation in orbit. Necessary processing fixtures (20) and (22) are also located on the convex side. Support equipment including power supplies (40, 42), CMG package (46) and electronic control package (44) are located on the convex side (24) of the shield facing the ram direction. Prior to operation in orbit the wake shield is oriented in reverse with the convex side facing the ram direction to provide cleaning by exposure to ambient atomic oxygen. The shield is then baked-out by being pointed directed at the sun to obtain heating for a suitable period.

Recognition techniques for extracting information from semistructured documents

NASA Astrophysics Data System (ADS)

Della Ventura, Anna; Gagliardi, Isabella; Zonta, Bruna

2000-12-01

Archives of optical documents are more and more massively employed, the demand driven also by the new norms sanctioning the legal value of digital documents, provided they are stored on supports that are physically unalterable. On the supply side there is now a vast and technologically advanced market, where optical memories have solved the problem of the duration and permanence of data at costs comparable to those for magnetic memories. The remaining bottleneck in these systems is the indexing. The indexing of documents with a variable structure, while still not completely automated, can be machine supported to a large degree with evident advantages both in the organization of the work, and in extracting information, providing data that is much more detailed and potentially significant for the user. We present here a system for the automatic registration of correspondence to and from a public office. The system is based on a general methodology for the extraction, indexing, archiving, and retrieval of significant information from semi-structured documents. This information, in our prototype application, is distributed among the database fields of sender, addressee, subject, date, and body of the document.

A system to preserve pedicab as cultural heritage in Solo city, Indonesia

NASA Astrophysics Data System (ADS)

Sari, Wahyu Apri W.; Handayani, Cahyaning D.; Putri, Yulina Rahayu L.; Dewa, Ratna T.

2017-06-01

Pedicab, a traditional three-wheeled transportation operated manually, has become the cultural heritage for decades, or even before the Indonesia Independence Day. Today, this kind of traditional transportation ought to compete with other modern transportation modes, such as bus, motorcycle, and taxi. This research investigated the possibility to divert the function of pedicab from conventional usage to the tourism usage that can provide more additional value to compete with other means of transportations. Descriptive qualitative was used as the method to gather the information, in addition to literature studies on the previous researches and the fundamental theories. We also did some interviews to the both sides, namely the public transportation users and the pedicab drivers. However, a city will be recognized if it has many uniqueness and cultural senses. By this consideration, it is expected that the pedicab drivers will have a capacity to approach and introduce their services directly to the tourists, which is supported by additional support systems, such as information and training system. Hopefully, the existence of pedicab can still be preserved for many decades ahead.

Nurse's perceptions and experiences of using of a mobile-phone-based Advanced Symptom Management System (ASyMS) to monitor and manage chemotherapy-related toxicity.

PubMed

Maguire, R; McCann, L; Miller, M; Kearney, N

2008-09-01

Many people diagnosed with cancer will receive chemotherapy as a core component of their care. Recent changes in the delivery of cancer services mean that patients frequently receive care on an out-patient basis and are therefore often required to manage related side effects at home without direct support from oncology health professionals. The use of information and communications technology may be seen as a means of supporting patients receiving chemotherapy in the home care setting. This mixed methods study, reports on the perceptions of nurses (n=35) who participated in a randomised controlled trial of a mobile phone based, Advanced Symptom Management System (ASyMS), in the management of chemotherapy-related toxicity in patients with breast, lung and colorectal cancer. Nurses' perceptions of ASyMS were evaluated at the start and the end of the study. Overall, they could see the benefits of ASyMS in the remote monitoring of chemotherapy toxicity and its role in facilitating early intervention and subsequent management, demonstrating the potential utility of the system within clinical practice.

Opioid analgesics and P-glycoprotein efflux transporters: a potential systems-level contribution to analgesic tolerance.

PubMed

Mercer, Susan L; Coop, Andrew

2011-01-01

Chronic clinical pain remains poorly treated. Despite attempts to develop novel analgesic agents, opioids remain the standard analgesics of choice in the clinical management of chronic and severe pain. However, mu opioid analgesics have undesired side effects including, but not limited to, respiratory depression, physical dependence and tolerance. A growing body of evidence suggests that P-glycoprotein (P-gp), an efflux transporter, may contribute a systems-level approach to the development of opioid tolerance. Herein, we describe current in vitro and in vivo methodology available to analyze interactions between opioids and P-gp and critically analyze P-gp data associated with six commonly used mu opioids to include morphine, methadone, loperamide, meperidine, oxycodone, and fentanyl. Recent studies focused on the development of opioids lacking P-gp substrate activity are explored, concentrating on structure-activity relationships to develop an optimal opioid analgesic lacking this systems-level contribution to tolerance development. Continued work in this area will potentially allow for delineation of the mechanism responsible for opioid-related P-gp up-regulation and provide further support for evidence based medicine supporting clinical opioid rotation.

The effect of professional culture on intrinsic motivation among physicians in an academic medical center.

PubMed

Janus, Katharina

2014-01-01

Today, most healthcare organizations aim to manage professionals' motivation through monetary incentives, such as pay for performance. However, addressing motivation extrinsically can involve negative effects, such as disturbed teamwork, gaming the system, and crowd-out of intrinsic motivation. To offset these side effects, it is crucial to support professionals' intrinsic motivation actively, which is largely determined by enjoyment- and obligation-based social norms that derive from professionals' culture. For this study, a professional culture questionnaire was designed and validated, the results of which uncovered three factors: relationship to work, relationship to colleagues, and relationship to organization. These factors served as independent variables for regression analyses. Second, Amabile's validated work preference inventory was used to measure intrinsic motivation as a dependent variable. The regression analysis was controlled for sex, age, and experience. The study revealed that relationship to work had the strongest (and a positive) impact on intrinsic motivation in general and on Amabile's intrinsic subscales, enjoyment and challenge. Relationship to organization had a negative impact on intrinsic motivation and both subscales, and relationship to colleagues showed a low positive significance for the intrinsic scale only. Healthcare organizations have mostly focused on targeting professionals' extrinsic motivation. However, managing dimensions of professional culture can help support professionals' intrinsic motivation without incurring the side effects of monetary incentives.

Performance-Based Financing to Strengthen the Health System in Benin: Challenging the Mainstream Approach

PubMed Central

Paul, Elisabeth; Lamine Dramé, Mohamed; Kashala, Jean-Pierre; Ekambi Ndema, Armand; Kounnou, Marcel; Codjovi Aïssan, Julien; Gyselinck, Karel

2018-01-01

Background: Performance-based financing (PBF) is often proposed as a way to improve health system performance. In Benin, PBF was launched in 2012 through a World Bank-supported project. The Belgian Development Agency (BTC) followed suit through a health system strengthening (HSS) project. This paper analyses and draws lessons from the experience of BTC-supported PBF alternative approach – especially with regards to institutional aspects, the role of demand-side actors, ownership, and cost-effectiveness – and explores the mechanisms at stake so as to better understand how the "PBF package" functions and produces effects Methods: An exploratory, theory-driven evaluation approach was adopted. Causal mechanisms through which PBF is hypothesised to impact on results were singled out and explored. This paper stems from the co-authors’ capitalisation of experiences; mixed methods were used to collect, triangulate and analyse information. Results are structured along Witter et al framework. Results: Influence of context is strong over PBF in Benin; the policy is donor-driven. BTC did not adopt the World Bank’s mainstream PBF model, but developed an alternative approach in line with its HSS support programme, which is grounded on existing domestic institutions. The main features of this approach are described (decentralised governance, peer review verification, counter-verification entrusted to health service users’ platforms), as well as its adaptive process. PBF has contributed to strengthen various aspects of the health system and led to modest progress in utilisation of health services, but noticeable improvements in healthcare quality. Three mechanisms explaining observed outcomes within the context are described: comprehensive HSS at district level; acting on health workers’ motivation through a complex package of incentives; and increased accountability by reinforcing dialogue with demand-side actors. Cost-effectiveness and sustainability issues are also discussed. Conclusion: BTC’s alternative PBF approach is both promising in terms of effects, ownership and sustainability, and less resource consuming. This experience testifies that PBF is not a uniform or rigid model, and opens the policy ground for recipient governments to put their own emphasis and priorities and design ad hoc models adapted to their context specificities. However, integrating PBF within the normal functioning of local health systems, in line with other reforms, is a big challenge. PMID:29325401

Nanotechnology-Based Drug Delivery Systems for Melanoma Antitumoral Therapy: A Review

PubMed Central

Rigon, Roberta Balansin; Oyafuso, Márcia Helena; Fujimura, Andressa Terumi; do Prado, Alice Haddad; Gremião, Maria Palmira Daflon

2015-01-01

Melanoma (MEL) is a less common type of skin cancer, but it is more aggressive with a high mortality rate. The World Cancer Research Fund International (GLOBOCAN 2012) estimates that there were 230,000 new cases of MEL in the world in 2012. Conventional MEL treatment includes surgery and chemotherapy, but many of the chemotherapeutic agents used present undesirable properties. Drug delivery systems are an alternative strategy by which to carry antineoplastic agents. Encapsulated drugs are advantageous due to such properties as high stability, better bioavailability, controlled drug release, a long blood circulation time, selective organ or tissue distribution, a lower total required dose, and minimal toxic side effects. This review of scientific research supports applying a nanotechnology-based drug delivery system for MEL therapy. PMID:26078967

Efficient proof of ownership for cloud storage systems

NASA Astrophysics Data System (ADS)

Zhong, Weiwei; Liu, Zhusong

2017-08-01

Cloud storage system through the deduplication technology to save disk space and bandwidth, but the use of this technology has appeared targeted security attacks: the attacker can deceive the server to obtain ownership of the file by get the hash value of original file. In order to solve the above security problems and the different security requirements of the files in the cloud storage system, an efficient and information-theoretical secure proof of ownership sceme is proposed to support the file rating. Through the K-means algorithm to implement file rating, and use random seed technology and pre-calculation method to achieve safe and efficient proof of ownership scheme. Finally, the scheme is information-theoretical secure, and achieve better performance in the most sensitive areas of client-side I/O and computation.

Nanotechnology-Based Drug Delivery Systems for Melanoma Antitumoral Therapy: A Review.

PubMed

Rigon, Roberta Balansin; Oyafuso, Márcia Helena; Fujimura, Andressa Terumi; Gonçalez, Maíra Lima; do Prado, Alice Haddad; Gremião, Maria Palmira Daflon; Chorilli, Marlus

2015-01-01

Melanoma (MEL) is a less common type of skin cancer, but it is more aggressive with a high mortality rate. The World Cancer Research Fund International (GLOBOCAN 2012) estimates that there were 230,000 new cases of MEL in the world in 2012. Conventional MEL treatment includes surgery and chemotherapy, but many of the chemotherapeutic agents used present undesirable properties. Drug delivery systems are an alternative strategy by which to carry antineoplastic agents. Encapsulated drugs are advantageous due to such properties as high stability, better bioavailability, controlled drug release, a long blood circulation time, selective organ or tissue distribution, a lower total required dose, and minimal toxic side effects. This review of scientific research supports applying a nanotechnology-based drug delivery system for MEL therapy.

Management of Side Effects of Novel Therapies for Multiple Myeloma: Consensus Statements Developed by the International Myeloma Foundation’s Nurse Leadership Board

PubMed Central

Bertolotti, Page; Bilotti, Elizabeth; Colson, Kathleen; Curran, Kathleen; Doss, Deborah; Faiman, Beth; Gavino, Maria; Jenkins, Bonnie; Lilleby, Kathy; Love, Ginger; Mangan, Patricia A.; McCullagh, Emily; Miceli, Teresa; Miller, Kena; Rogers, Kathryn; Rome, Sandra; Sandifer, Stacey; Smith, Lisa C.; Tariman, Joseph D.; Westphal, Jeanne

2014-01-01

Nurses play an essential role in managing the care of patients with multiple myeloma, who require education and support to receive and adhere to optimal therapy. The International Myeloma Foundation created a Nurse Leadership Board comprised of oncology nurses from leading cancer centers and community practices. An assessment survey identified the need for specific recommendations for managing key side effects of novel antimyeloma agents. Myelosuppression, thromboembolic events, peripheral neuropathy, steroid toxicities, and gastrointestinal side effects were selected for the first consensus statements. The board developed recommendations for healthcare providers in any medical setting, including grading of side-effect toxicity and strategies for managing the side effects in general, with specific recommendations pertaining to the novel agents. PMID:18490252

Injury reduction opportunities of far side impact countermeasures.

PubMed

Bostrom, Ola; Gabler, Hampton C; Digges, Kennerly; Fildes, Brian; Sunnevang, Cecilia

2008-10-01

Over 17,000 non-struck or far side occupants in side and rollover crashes are seriously or fatally injured annually in the US. Although no legal or rating tests exist for far side crashes, test methods including appropriate dummies as well as countermeasures have been recently suggested. The aim of this study was to establish the incidence and risk of injury / fatality as a function of vehicle change in velocity (Deltav) for the most frequent injuries of belted, far side occupants in side impacts. The study was based upon the NASS/CDS 1995-2006 records of 5,653 occupants exposed to a far side crash. 401 of these were seriously or fatally injured. Combining this data with new and previously published crash test results, the potential opportunities of various concepts of far side countermeasures were evaluated. Head/thorax injuries caused by interaction with the struck side interior were found to dominate. Countermeasures such as side support airbags and altered three-point belt geometry (e.g. four-point belts) are relevant for Deltav of at least 20-30 km/h. The opportunity for mitigating AIS3+ injuries in these severity ranges was found to be 19%- 57%. Countermeasures such as struck-side curtains are able to provide cushioning at Deltav 30 to 50 km/h, which would cover almost a third of all fatalities.

High Level Analysis, Design and Validation of Distributed Mobile Systems with CoreASM

NASA Astrophysics Data System (ADS)

Farahbod, R.; Glässer, U.; Jackson, P. J.; Vajihollahi, M.

System design is a creative activity calling for abstract models that facilitate reasoning about the key system attributes (desired requirements and resulting properties) so as to ensure these attributes are properly established prior to actually building a system. We explore here the practical side of using the abstract state machine (ASM) formalism in combination with the CoreASM open source tool environment for high-level design and experimental validation of complex distributed systems. Emphasizing the early phases of the design process, a guiding principle is to support freedom of experimentation by minimizing the need for encoding. CoreASM has been developed and tested building on a broad scope of applications, spanning computational criminology, maritime surveillance and situation analysis. We critically reexamine here the CoreASM project in light of three different application scenarios.

Pumping Optimization Model for Pump and Treat Systems - 15091

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, S.; Ivarson, Kristine A.; Karanovic, M.

2015-01-15

Pump and Treat systems are being utilized to remediate contaminated groundwater in the Hanford 100 Areas adjacent to the Columbia River in Eastern Washington. Design of the systems was supported by a three-dimensional (3D) fate and transport model. This model provided sophisticated simulation capabilities but requires many hours to calculate results for each simulation considered. Many simulations are required to optimize system performance, so a two-dimensional (2D) model was created to reduce run time. The 2D model was developed as a equivalent-property version of the 3D model that derives boundary conditions and aquifer properties from the 3D model. It producesmore » predictions that are very close to the 3D model predictions, allowing it to be used for comparative remedy analyses. Any potential system modifications identified by using the 2D version are verified for use by running the 3D model to confirm performance. The 2D model was incorporated into a comprehensive analysis system (the Pumping Optimization Model, POM) to simplify analysis of multiple simulations. It allows rapid turnaround by utilizing a graphical user interface that: 1 allows operators to create hypothetical scenarios for system operation, 2 feeds the input to the 2D fate and transport model, and 3 displays the scenario results to evaluate performance improvement. All of the above is accomplished within the user interface. Complex analyses can be completed within a few hours and multiple simulations can be compared side-by-side. The POM utilizes standard office computing equipment and established groundwater modeling software.« less

Flexible high-resolution display systems for the next generation of radiology reading rooms

NASA Astrophysics Data System (ADS)

Caban, Jesus J.; Wood, Bradford J.; Park, Adrian

2007-03-01

A flexible, scalable, high-resolution display system is presented to support the next generation of radiology reading rooms or interventional radiology suites. The project aims to create an environment for radiologists that will simultaneously facilitate image interpretation, analysis, and understanding while lowering visual and cognitive stress. Displays currently in use present radiologists with technical challenges to exploring complex datasets that we seek to address. These include resolution and brightness, display and ambient lighting differences, and degrees of complexity in addition to side-by-side comparison of time-variant and 2D/3D images. We address these issues through a scalable projector-based system that uses our custom-designed geometrical and photometrical calibration process to create a seamless, bright, high-resolution display environment that can reduce the visual fatigue commonly experienced by radiologists. The system we have designed uses an array of casually aligned projectors to cooperatively increase overall resolution and brightness. Images from a set of projectors in their narrowest zoom are combined at a shared projection surface, thus increasing the global "pixels per inch" (PPI) of the display environment. Two primary challenges - geometric calibration and photometric calibration - remained to be resolved before our high-resolution display system could be used in a radiology reading room or procedure suite. In this paper we present a method that accomplishes those calibrations and creates a flexible high-resolution display environment that appears seamless, sharp, and uniform across different devices.

Geometric Corrections for Topographic Distortion from Side Scan Sonar Data Obtained by ANKOU System

NASA Astrophysics Data System (ADS)

Yamamoto, Fujio; Kato, Yukihiro; Ogasawara, Shohei

The ANKOU is a newly developed, full ocean depth, long-range vector side scan sonar system. The system provides real time vector side scan sonar data to produce backscattering images and bathymetric maps for seafloor swaths up to 10 km on either side of ship's centerline. Complete geometric corrections are made using towfish attitude and cross-track distortions known as foreshortening and layover caused by violation of the flat bottom assumption. Foreshortening and layover refers to pixels which have been placed at an incorrect cross-track distance. Our correction of this topographic distortion is accomplished by interpolating a bathymetric profile and ANKOU phase data. We applied these processing techniques to ANKOU backscattering data obtained from off Boso Peninsula, and confirmed their efficiency and utility for making geometric corrections of side scan sonar data.

Electrochemical CO2 Reduction via Gas-Phase Catholyte

NASA Astrophysics Data System (ADS)

Carter, Brittany E.; Nesbitt, Nathan T.; D'Imperio, Luke A.; Naughton, Jeffrey R.; Courtney, Dave T.; Shepard, Steve; Burns, Michael J.; Vermaas, David A.; Smith, Wilson A.; Naughton, Michael J.

Reducing CO2 to CO through electrolysis, for the eventual conversion to hydrocarbons, provides a path towards utility-scale seasonal storage of renewable energy. Electrochemical reduction of CO2 has previously been achieved using a two chamber system. The chambers are typically separated by a semipermeable Nafion membrane, with an oxygen evolution catalyst anode on one side, a gold cathode on the other, and a solution containing CO2 on both sides. If instead, CO2 gas was in the second chamber, the reaction should yield more CO formed from CO2 at a given overpotential; this would result from the increased concentration of CO2 at the cathode surface and more facile mass transport of the CO and CO2. With liquid in one chamber and gas in the other, electrolysis is performed by integrating the cathode onto the semipermeable Nafion membrane. This membrane electrode assembly is fabricated via nanoimprint lithography (NIL), simultaneously achieving high active surface area and permeability. Challenges to the Nafion NIL process, and the performance of the system in CO2 reduction, will be presented. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship under Grant No. (DGE-1258923).

Improved ITOS attitude control system with Hall generator brushless motor and earth-splitting technique

NASA Technical Reports Server (NTRS)

Peacock, W. M.

1971-01-01

The ITOS with an improved attitude control system is described. A Hall generator brushless dc torque motor will replace the brush dc torque motor on ITOS-I and ITOS-A (NOAA-1). The four attitude horizon sensors will be replaced with two CO2 sensors for better horizon definition. An earth horizon splitting technique will be used to keep the earth facing side of the satellite toward earth even if the desired circular orbit is not achieved. The external appearance of the pitch control subsystem differs from TIROS-M (ITOS-1) and ITOS-A (NOAA-1) in that two instead of one pitch control electronics (PCE) boxes are used. Two instead of four horizon sensors will be used and one instead of two mirrors will be used for sensor scanning. The brushless motor will eliminate the requirement for brushes, strain gages and the telemetry for the brush wear. A single rotating flywheel, supported by a single bearing provides the gyroscopic stability and the required momentum interchange to keep one side of the satellite facing the earth. Magnetic torquing against the earth's magnetic field eliminates the requirement for expendable propellants which would limit satellite life in orbit.

Highly accurate pulse-per-second timing distribution over optical fibre network using VCSEL side-mode injection

NASA Astrophysics Data System (ADS)

Wassin, Shukree; Isoe, George M.; Gamatham, Romeo R. G.; Leitch, Andrew W. R.; Gibbon, Tim B.

2017-01-01

Precise and accurate timing signals distributed between a centralized location and several end-users are widely used in both metro-access and speciality networks for Coordinated Universal Time (UTC), GPS satellite systems, banking, very long baseline interferometry and science projects such as SKA radio telescope. Such systems utilize time and frequency technology to ensure phase coherence among data signals distributed across an optical fibre network. For accurate timing requirements, precise time intervals should be measured between successive pulses. In this paper we describe a novel, all optical method for quantifying one-way propagation times and phase perturbations in the fibre length, using pulse-persecond (PPS) signals. The approach utilizes side mode injection of a 1550nm 10Gbps vertical cavity surface emitting laser (VCSEL) at the remote end. A 125 μs one-way time of flight was accurately measured for 25 km G655 fibre. Since the approach is all-optical, it avoids measurement inaccuracies introduced by electro-optical conversion phase delays. Furthermore, the implementation uses cost effective VCSEL technology and suited to a flexible range of network architectures, supporting a number of end-users conducting measurements at the remote end.

Future therapeutic options in food allergy.

PubMed

Eigenmann, P A

2003-12-01

Up to 5% of young children and 2% of adults suffer from food allergy. Among them many have immunoglobulin E (IgE)-mediated food allergy, a condition with potentially fatal allergic reactions. Several studies have addressed possible definite treatment options for food allergy. Immunotherapy, by the oral route or by systemic injections shows promising preliminary results, but current interpretation of these therapeutic options are mostly handicapped by studies with insufficient scientific support, or by severe side-effects. Currently, no studies can support pharmacotherapy. Finally, most promising results were recently published with anti-IgE antibodies in a human trial, or various approaches in a mouse model of food allergy (chinese herbal medicine, specific modulation of the T cell response). Rapidly evolving findings might provide hope for a cure of food allergy in the near future.

Experimental and numeric investigation of Impella pumps as cavopulmonary assistance for a failing Fontan.

PubMed

Haggerty, Christopher M; Fynn-Thompson, Francis; McElhinney, Doff B; Valente, Anne Marie; Saikrishnan, Neelakantan; Del Nido, Pedro J; Yoganathan, Ajit P

2012-09-01

This study sought to evaluate the performance of microaxial ventricular assist devices for the purposes of supporting failing Fontan physiology by decreasing central venous pressure. Three Abiomed Impella pumps (Abiomed, Inc, Danvers, Mass) were evaluated in a mock circulatory system of the Fontan circuit. The local response of pressures and flows to pump function was assessed as a function of pump speed and pulmonary vascular resistance at a high baseline central venous pressure. For one device, subsequent modeling studies were conducted using a lumped parameter model of the single ventricle circuit. The left ventricular devices (Impella 2.5, 5.0) were shown to be suboptimal as single device solutions for cavopulmonary support. The small area of these devices relative to vessel diameter led to significant flow recirculation without an obstructive separator in place. Furthermore, downstream pressure augmentation adversely affected the pressure in the superior vena cava. The use of 2 devices would be mandatory for successful support. The right-sided device (Impella RP), whose outflow was positioned in the left pulmonary artery, demonstrated decreased flow recirculation and did not impede superior caval venous flow. Although static pressure is still required to drive flow through the opposite lung, numeric modeling demonstrated the potential for modest but significant improvements in lowering the central venous pressure (2-8 mm Hg). Left-sided microaxial pumps are not well suited for cavopulmonary support because of severe flow recirculation and the need for multiple devices. The right-ventricular Impella device provides improved performance by directing flow into the pulmonary artery, resulting in modest decreases in central venous pressure. Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

Drapery assembly including insulated drapery liner

DOEpatents

Cukierski, Gwendolyn

1983-01-01

A drapery assembly is disclosed for covering a framed wall opening, the assembly including drapery panels hung on a horizontal traverse rod, the rod having a pair of master slides and means for displacing the master slides between open and closed positions. A pair of insulating liner panels are positioned behind the drapery, the remote side edges of the liner panels being connected with the side portions of the opening frame, and the adjacent side edges of the liner panels being connected with a pair of vertically arranged center support members adapted for sliding movement longitudinally of a horizontal track member secured to the upper horizontal portion of the opening frame. Pivotally arranged brackets connect the center support members with the master slides of the traverse rod whereby movement of the master slides to effect opening and closing of the drapery panels effects simultaneous opening and closing of the liner panels.

Cassettes for solid-oxide fuel cell stacks and methods of making the same

DOEpatents

Weil, K. Scott; Meinhardt, Kerry D; Sprenkle, Vincent L

2012-10-23

Solid-oxide fuel cell (SOFC) stack assembly designs are consistently investigated to develop an assembly that provides optimal performance, and durability, within desired cost parameters. A new design includes a repeat unit having a SOFC cassette and being characterized by a three-component construct. The three components include an oxidation-resistant, metal window frame hermetically joined to an electrolyte layer of a multi-layer, anode-supported ceramic cell and a pre-cassette including a separator plate having a plurality of vias that provide electrical contact between an anode-side collector within the pre-cassette and a cathode-side current collector of an adjacent cell. The third component is a cathode-side seal, which includes a standoff that supports a cathode channel spacing between each of the cassettes in a stack. Cassettes are formed by joining the pre-cassette and the window frame.

[Understanding chair-side digital technology for stomatology from an engineering viewpoint].

PubMed

Zhao, Y J; Wang, Y

2018-04-09

In recent years with the rapid development of digital technology for stomatology, the application field, application model, technical features and technical connotation of the chair-side digital technology has got development and change. The open modular system has gradually replaced the traditional closed system, and the application field of digital technology is no longer limited to chair-side dental restoration, it also has been extend to various kinds of chair-side digital treatment-assisted technology. In this paper, from the engineering point of view, the up to date general connotation of chair-side digital technology was explained, the characteristics and the development of each unit in chair-side digital technology were analyzed, and the application pattern and the localization status were also discussed in this paper. The aim of this paper was to introduce the trend of chair-side digital technological to readers and to better guide clinical application.

The effect of multiple external representations (MERs) worksheets toward complex system reasoning achievement

NASA Astrophysics Data System (ADS)

Sumarno; Ibrahim, M.; Supardi, Z. A. I.

2018-03-01

The application of a systems approach to assessing biological systems provides hope for a coherent understanding of cell dynamics patterns and their relationship to plant life. This action required the reasoning about complex systems. In other sides, there were a lot of researchers who provided the proof about the instructional successions. They involved the multiple external representations which improved the biological learning. The researcher conducted an investigation using one shoot case study design which involved 30 students in proving that the MERs worksheets could affect the student's achievement of reasoning about complex system. The data had been collected based on test of reasoning about complex system and student's identification result who worked through MERs. The result showed that only partially students could achieve reasoning about system complex, but their MERs skill could support their reasoning ability of complex system. This study could bring a new hope to develop the MERs worksheet as a tool to facilitate the reasoning about complex system.

Successful resuscitation of cardiac arrest caused by CO2 embolism with intra-aortic injection of epinephrine during off-pump coronary bypass surgery -a case report-.

PubMed

Lee, Choon Soo; Yoon, Yeo Sam; Shim, Jae-Kwang; Lim, Hyun Kyoung

2013-12-01

Although compressed gas (CO2) blowers have been used safely to aid accurate grafting during off-pump coronary bypass surgery, hemodynamic collapse due to gas embolism into the right coronary artery may occur. Supportive measures to facilitate gas clearance by increasing the coronary perfusion pressure have been reported to be successful in restoring hemodynamic stability. However, right ventricular dysfunction and atrioventricular nodal ischemia may hinder effective systemic delivery of the vasoactive medications, even when performing resuscitative measures such as direct cardiac massage. We herein report a case of cardiac arrest that was caused by a right coronary gas embolism and that could not be restored by cardiac resuscitation. When supportive measures fail, direct aortic injection of epinephrine to increase the coronary perfusion pressure can be attempted before initiating cardiopulmonary bypass, and this approach may be life-saving in situations that limit systemic drug delivery from the venous side despite the performance of direct cardiac massage.

Successful resuscitation of cardiac arrest caused by CO2 embolism with intra-aortic injection of epinephrine during off-pump coronary bypass surgery -a case report-

PubMed Central

Lee, Choon Soo; Yoon, Yeo Sam; Shim, Jae-Kwang

2013-01-01

Although compressed gas (CO2) blowers have been used safely to aid accurate grafting during off-pump coronary bypass surgery, hemodynamic collapse due to gas embolism into the right coronary artery may occur. Supportive measures to facilitate gas clearance by increasing the coronary perfusion pressure have been reported to be successful in restoring hemodynamic stability. However, right ventricular dysfunction and atrioventricular nodal ischemia may hinder effective systemic delivery of the vasoactive medications, even when performing resuscitative measures such as direct cardiac massage. We herein report a case of cardiac arrest that was caused by a right coronary gas embolism and that could not be restored by cardiac resuscitation. When supportive measures fail, direct aortic injection of epinephrine to increase the coronary perfusion pressure can be attempted before initiating cardiopulmonary bypass, and this approach may be life-saving in situations that limit systemic drug delivery from the venous side despite the performance of direct cardiac massage. PMID:24427464

Spatializing Emotion: No Evidence for a Domain-General Magnitude System.

PubMed

Pitt, Benjamin; Casasanto, Daniel

2017-11-22

People implicitly associate different emotions with different locations in left-right space. Which aspects of emotion do they spatialize, and why? Across many studies people spatialize emotional valence, mapping positive emotions onto their dominant side of space and negative emotions onto their non-dominant side, consistent with theories of metaphorical mental representation. Yet other results suggest a conflicting mapping of emotional intensity (a.k.a., emotional magnitude), according to which people associate more intense emotions with the right and less intense emotions with the left - regardless of their valence; this pattern has been interpreted as support for a domain-general system for representing magnitudes. To resolve the apparent contradiction between these mappings, we first tested whether people implicitly map either valence or intensity onto left-right space, depending on which dimension of emotion they attend to (Experiments 1a, b). When asked to judge emotional valence, participants showed the predicted valence mapping. However, when asked to judge emotional intensity, participants showed no systematic intensity mapping. We then tested an alternative explanation of findings previously interpreted as evidence for an intensity mapping (Experiments 2a, b). These results suggest that previous findings may reflect a left-right mapping of spatial magnitude (i.e., the size of a salient feature of the stimuli) rather than emotion. People implicitly spatialize emotional valence, but, at present, there is no clear evidence for an implicit lateral mapping of emotional intensity. These findings support metaphor theory and challenge the proposal that mental magnitudes are represented by a domain-general metric that extends to the domain of emotion. Copyright © 2017 Cognitive Science Society, Inc.

Cerebral specialization for speech production in persons with Down syndrome.

PubMed

Heath, M; Elliott, D

1999-09-01

The study of cerebral specialization in persons with Down syndrome (DS) has revealed an anomalous pattern of organization. Specifically, dichotic listening studies (e.g., Elliott & Weeks, 1993) have suggested a left ear/right hemisphere dominance for speech perception for persons with DS. In the current investigation, the cerebral dominance for speech production was examined using the mouth asymmetry technique. In right-handed, nonhandicapped subjects, mouth asymmetry methodology has shown that during speech, the right side of the mouth opens sooner and to a larger degree then the left side (Graves, Goodglass, & Landis, 1982). The phenomenon of right mouth asymmetry (RMA) is believed to reflect the direct access that the musculature on the right side of the face has to the left hemisphere's speech production systems. This direct access may facilitate the transfer of innervatory patterns to the muscles on the right side of the face. In the present study, the lateralization for speech production was investigated in 10 right-handed participants with DS and 10 nonhandicapped subjects. A RMA at the initiation and end of speech production occurred for subjects in both groups. Surprisingly, the degree of asymmetry between groups did not differ, suggesting that the lateralization of speech production is similar for persons with and persons without DS. These results support the biological dissociation model (Elliott, Weeks, & Elliott, 1987), which holds that persons with DS display a unique dissociation between speech perception (right hemisphere) and speech production (left hemisphere). Copyright 1999 Academic Press.

Application of VSC-HVDC with Shunt Connected SMES for Compensation of Power Fluctuation

NASA Astrophysics Data System (ADS)

Linn, Zarchi; Kakigano, Hiroaki; Miura, Yushi; Ise, Toshifumi

This paper describes the application of VSC-HVDC (High Voltage DC Transmission using Voltage Source Converter) with shunt connected SMES (Superconducting Magnetic Energy Storage) for compensation of power fluctuation caused by fluctuating power source such as photovoltaics and wind turbines. The objectives of this proposed system is to smooth out fluctuating power in one terminal side of HVDC in order to avoid causing power system instability and frequency deviation by absorbing or providing power according to the system requirement while another terminal side power is fluctuated. The shunt connected SMES charges and discharges the energy to and from the dc side and it compensates required power of fluctuation to obtain constant power flow in one terminal side of VSC-HVDC system. This system configuration has ability for power system stabilization in the case of power fluctuation from natural energy source. PSCAD/EMTDC simulation is used to evaluate the performance of applied system configuration and control method.

Biomechanical analysis of protective countermeasures in underride motor vehicle accidents - biomed 2009.

PubMed

Kumar, Sri; Enz, Bruce; Ponder, Perry L; Anderson, Bob

2009-01-01

Traffic safety has been significantly improved over the past several decades reducing injury and fatality rates. However, there is a paucity of research effort to address the safety issues in underride accidents, specifically the side underride crashes. It is well known that the compromise of occupant space in the vehicle leads to a higher probability of serious or fatal injuries. A better understanding of occupant protection and mechanism of injuries involved in side underride accidents assists in the advancement of safety measures. The present work evaluates the injury potential to occupants during side underride crashes using the car-to-trailer crash methodology. Four crash tests were conducted into the side of a stationary trailer fitted with the side underride guard system (SURG). The SURG used in these tests is 25% lighter than the previous design. A 5th percentile hybrid III female dummy was placed in the driver seat and restrained with the three-point lap and shoulder harness. The anthropometric dummy was instrumented with a head triaxial accelerometer, a chest triaxal accelerometer, a load cell to measure neck force and moment, and a load cell to measure the femur force. The vehicle acceleration was measured using a traxial accelerometer in the rear center tunnel. High speed, standard video and still photos were taken. In all tests, the intrusion was limited to the front structure of the vehicle without any significant compromise to the occupant space. Results indicate that the resultant head and chest accelerations, head injury criterion (HIC), neck force and moment, and femur force were well below the injury tolerance. The present findings support the hypothesis that the SURG not only limits or eliminates the intrusion into the occupant space but also results in biomechanical injury values well below the tolerance limit in motor vehicle crashes.

Recent Advances in Solar Sail Propulsion at NASA

NASA Technical Reports Server (NTRS)

Johnson, Les; Young, Roy M.; Montgomery, Edward E., IV

2006-01-01

Supporting NASA's Science Mission Directorate, the In-Space Propulsion Technology Program is developing solar sail propulsion for use in robotic science and exploration of the solar system. Solar sail propulsion will provide longer on-station operation, increased scientific payload mass fraction, and access to previously inaccessible orbits for multiple potential science missions. Two different 20-meter solar sail systems were produced and successfully completed functional vacuum testing last year in NASA Glenn's Space Power Facility at Plum Brook Station, Ohio. The sails were designed and developed by ATK Space Systems and L'Garde, respectively. These sail systems consist of a central structure with four deployable booms that support the sails. This sail designs are robust enough for deployments in a one atmosphere, one gravity environment, and are scalable to much larger solar sails-perhaps as much as 150 meters on a side. In addition, computation modeling and analytical simulations have been performed to assess the scalability of the technology to the large sizes (>150 meters) required for first generation solar sails missions. Life and space environmental effects testing of sail and component materials are also nearly complete. This paper will summarize recent technology advancements in solar sails and their successful ambient and vacuum testing.

Central nervous system side effects associated with zolpidem treatment.

PubMed

Toner, L C; Tsambiras, B M; Catalano, G; Catalano, M C; Cooper, D S

2000-01-01

Zolpidem is one of the newer medications developed for the treatment of insomnia. It is an imidazopyridine agent that is an alternative to the typical sedative-hypnotic agents. Zolpidem use is gaining favor because of its efficacy and its side effect profile, which is milder and less problematic than that of the benzodiazepines and barbiturates used to treat insomnia. Still, side effects are not uncommon with zolpidem use. We report a series of cases in which the patients developed delirium, nightmares and hallucinations during treatment with zolpidem. We will review its pharmacology, discuss previous reports of central nervous system side effects, examine the impact of drug interactions with concurrent use of antidepressants, examine gender differences in susceptibility to side effects, and explore the significance of protein binding in producing side effects.

Residents and urban greenways:  Modeling support for the Atlanta BeltLine

Treesearch

Nathan P. Palardy; B. Bynum Boley; Cassandra Johnson Gaither

2018-01-01

Urban greenways have received significant attention due to their many publicized benefits and costs that make them contentious recreational developments. Most prior studies have approached urban greenways from a demand-side perspective solely focused on their users. This study adds to the literature by taking a supply-side approach to assessing resident attitudes...

76 FR 74012 - Airworthiness Directives; the Boeing Company Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-30

... new structural members and new tie rod(s) and attach fittings on the left and right sides of the... members and new tie rod(s) and attach fittings on the left and right sides of the lowered ceiling support...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Boeing Company Model 777-200...

Numerical simulation of steady state three-dimensional groundwater flow near lakes

USGS Publications Warehouse

Winter, Thomas C.

1978-01-01

Numerical simulation of three-dimensional groundwater flow near lakes shows that the continuity of the boundary encompassing the local groundwater flow system associated with a lake is the key to understanding the interaction of a lake with the groundwater system. The continuity of the boundary can be determined by the presence of a stagnation zone coinciding with the side of the lake nearest the downgradient side of the groundwater system. For most settings modeled in this study the stagnation zone underlies the lakeshore, and it generally follows its curvature. The length of the stagnation zone is controlled by the geometry of the lake's drainage basin divide on the side of the lake nearest the downgradient side of the groundwater system. In the case of lakes that lose water to the groundwater system, three-dimensional modeling also allows for estimating the area of lake bed through which outseepage takes place. Analysis of the effects of size and lateral and vertical distribution of aquifers within the groundwater system on the outseepage from lakes shows that the position of the center point of the aquifer relative to the littoral zone on the side of the lake nearest the downgradient side of the groundwater system is a critical factor. If the center point is downslope from this part of the littoral zone, the local flow system boundary tends to be weak or outseepage occurs. If the center point is upslope from this littoral zone, the stagnation zone tends to be stronger (to have a higher head in relation to lake level), and outseepage is unlikely to occur.

Numerical Analysis of Flow-Induced Vibrations in Closed Side Branches

NASA Astrophysics Data System (ADS)

KníŽat, Branislav; Troják, Michal

2011-12-01

Vibrations occuring in closed side branches connected to a main pipe are a frequent problem during pipeline system operation. At the design stage of pipeline systems, this problem is sometimes overlooked or underestimated which can later lead to the shortening of the systems life cycle or may even cause injury. The aim of this paper is a numerical analysis of the start of self-induced vibrations on the edge of a closed side branch. Calculation conditions and obtained results are presented within.