Enhanced thermal and structural properties of partially phosphorylated polyvinyl alcohol - Aluminum phosphate (PPVA-Alpo4) nanocomposites with aluminium nitrate source

NASA Astrophysics Data System (ADS)

Saat, Asmalina Mohamed; Johan, Mohd Rafie

2017-12-01

Synthesis of AlPO4 nanocomposite depends on the ratio of aluminum to phosphate, method of synthesis and the source for aluminum and phosphate source used. Variation of phosphate and aluminum source used will form multiple equilibria reactions and affected by ions variability and concentration, stoichiometry, temperature during reaction process and especially the precipitation pH. Aluminum nitrate was used to produce a partially phosphorylated poly vinyl alcohol-aluminum phosphate (PPVA-AlPO4) nanocomposite with various nanoparticle shapes, structural and properties. Synthesis of PPVA-AlPO4 nanocomposite with aluminum nitrate shows enhancement of thermal and structural in comparison with pure PVA and modified PPVA. Thermogravimetric (TGA) analysis shows that the weight residue of PPVA-AlPO4 composite was higher than PPVA and PVA. X-ray diffraction (XRD) pattern of PVA shows a single peak broadening after the addition of phosphoric acid. Meanwhile, XRD pattern of PPVA-AlPO4 demonstrates multiple phases of AlPO4 in the nanocomposite. Field Emission Scanning Electron Microscopy (FESEM) confirmed the existence of multiple geometrical phases and nanosize of spherical particles.

Adsorption of gentian violet dyes in aqueous solution on microporous AlPOs molecular sieves synthesized by ionothermal method

NASA Astrophysics Data System (ADS)

Fortas, W.; Djelad, A.; Hasnaoui, M. A.; Sassi, M.; Bengueddach, A.

2018-02-01

In this work, AlPO-34, like-chabazite (CHA) zeolite, was ionothermally prepared using the ionic liquid (IL), 1-ethyl-3-methylimidazolium chloride [EMIMCl], as solvent. The solids obtained were characterized by x-ray powder diffraction (XRD), scanning electron microscopy (SEM), infrared spectroscopy (FTIR), thermal analysis (TG) and nitrogen adsorption/desorption at 77.3 K. The results show that the ionic liquid is occluded in the AlPO-34 framework and consequently it acts also as a structure-directing agent. The variation of chemical composition led to AlPO-34 materials with different crystal sizes and morphologies. The well crystallized AlPO-34 material was used as adsorbent for Crystal Violet (CV) dye removal from aqueous solutions. The effect of adsorption parameters such as pH and initial concentration were investigated. It was found that adsorption dyes is favorable at pH = 6. The adsorption isotherm data follow the Langmuir equation in which parameters are calculated. The selected AlPO-34 sample exhibited a high crystal violet dye removal of 46.08 mg g-1 at pH = 6.

Host and adsorbate dynamics in silicates with flexible frameworks: Empirical force field simulation of water in silicalite

NASA Astrophysics Data System (ADS)

Bordat, Patrice; Cazade, Pierre-André; Baraille, Isabelle; Brown, Ross

2010-03-01

Molecular dynamics simulations are performed on the pure silica zeolite silicalite (MFI framework code), maintaining via a new force field both framework flexibility and realistic account of electrostatic interactions with adsorbed water. The force field is similar to the well-known "BKS" model [B. W. H. van Beest et al., Phys. Rev. Lett. 64, 1955 (1990)], but with reduced partial atomic charges and reoptimized covalent bond potential wells. The present force field reproduces the monoclinic to orthorhombic transition of silicalite. The force field correctly represents the hydrophobicity of pure silica silicalite, both the adsorption energy, and the molecular diffusion constants of water. Two types of adsorption, specific and weak unspecific, are predicted on the channel walls and at the channel intersection. We discuss molecular diffusion of water in silicalite, deducing a barrier to crossing between the straight and the zigzag channels. Analysis of the thermal motion shows that at room temperature, framework oxygen atoms incurring into the zeolite channels significantly influence the dynamics of adsorbed water.

Immobilization of radioactive iodine in silver aluminophosphate glasses.

PubMed

Lemesle, Thomas; Méar, François O; Campayo, Lionel; Pinet, Olivier; Revel, Bertrand; Montagne, Lionel

2014-01-15

Silver aluminophosphate glasses have been investigated as matrices for the immobilization of radioactive iodine. In this study, up to 28mol% AgI have been incorporated without volatilization thanks to a low temperature synthesis protocol. Alumina was added in the composition in order to increase the glass transition temperature for a better thermal stability in a repository conditions. Two series of glasses have been investigated, based on AgPO3 and Ag5P3O10 compositions, and with 0-5mol% Al2O3. We report (31)P, (27)Al and (109)Ag NMR study of these glasses, including advanced measurement of the connectivities through {(27)Al}-(31)P cross-polarization and (31)P-(31)P double-quantum correlation. We confirm that AgI is inserted in the aluminophosphate glasses and does not form clusters. AgI does not induce any modification of the glass polymerization but only an expansion of the network. Despite no evidence for crystallization could be obtained from XRD, NMR revealed that the introduction of AgI induces an exclusion of alumina from the network, leading to the crystallization of aluminophosphate phases such as Al(PO3)3 or AlPO4. As a consequence, despite NMR gives evidence for the presence of aluminophosphate bonds, only a limited effect of alumina addition on thermal properties is observed. Copyright © 2013 Elsevier B.V. All rights reserved.

Synthesis and hydrophobic adsorption properties of microporous/mesoporous hybrid materials.

PubMed

Hu, Qin; Li, Jinjun; Qiao, Shizhang; Hao, Zhengping; Tian, Hua; Ma, Chunyan; He, Chi

2009-05-30

Hybrid materials of silicalite-1 (Sil-1)-coated SBA-15 particles (MSs) have been successfully synthesized by crystallization process under hydrothermal conditions. These MSs materials were characterized by X-ray diffraction, nitrogen adsorption/desorption and TEM techniques, which illustrated that the silicalite-1-coated SBA-15 particles were successfully prepared and had large pore volume and hierarchical pore size distribution. Further experimental studies indicated that longer crystallization time under basic condition caused the mesostructure of SBA-15 materials to collapse destructively and higher calcination temperature tended to disrupt the long-range mesoscopic order while they had little influence on the phase of microcrystalline silicalite-1 zeolite. The resultant MSs materials were investigated by estimating dynamic adsorption capacity under dry and wet conditions to evaluate their adsorptive and hydrophobic properties. The hydrophobicity index (HI) value followed the sequence of silicalite-1>MSs>SBA-15, which revealed that the SBA-15 particles coated with the silicalite-1 seeds enhanced the surface hydrophobicity, and also were consistent with FTIR results. Our studies show that MSs materials combined the advantages of the ordered mesoporous material (high adsorptive capacity, large pore volume) and silicalite-1 zeolite (super-hydrophobic property, high hydrothermal stability), and the presence of micropores directly led to an increase in the dynamic adsorption capacity of benzene under dry and wet conditions.

An Ongoing Program for Monitoring the Moon for Meteoroid Impacts (Abstract)

NASA Astrophysics Data System (ADS)

Cudnik, B.; Saganti, S.; Ali, F.; Ali, S.; Beharie, T.; Anugwom, B.

2017-12-01

(Abstract only) Lunar meteor impacts are surprisingly frequent phenomena, with well over one hundred observable events occurring each year. Of these a little over half arise from members of annual meteor showers (e.g. Perseids, Leonids, etc.), with the rest being sporadic in origin. Five years ago, I (BC) introduced to the SAS Symposium the idea of observing lunar meteoroid impact phenomena and applying these observations to a space mission (LADEE-Lunar Atmosphere and Dust Environment Explorer) that launched the following year. Now, five years later I revisit and reintroduce the activities of the Association of Lunar and Planetary Observers-Lunar Meteoritic Impact Search (ALPO-LMIS) section and share some of the latest observations that have been received. For over 17 years now, ALPO has hosted the LMIS section, for which I have served as coordinator since its inception. In this paper, I will revisit the main ideas of the earlier paper, share some recent observations of lunar meteors, and provide new initiatives and projects interested persons can participate in.

A modeling study of methane hydrate decomposition in contact with the external surface of zeolites.

PubMed

Smirnov, Konstantin S

2017-08-30

The behavior of methane hydrate (MH) enclosed between the (010) surfaces of the silicalite-1 zeolite was studied by means of molecular dynamics simulations at temperatures of 150 and 250 K. Calculations reveal that the interaction with the hydrophilic surface OH groups destabilizes the clathrate structure of hydrate. While MH mostly conserves the structure in the simulation at the low temperature, thermal motion at the high temperature breaks the fragilized cages of H-bonded water molecules, thus leading to the release of methane. The dissociation proceeds in a layer-by-layer manner starting from the outer parts of the MH slab until complete hydrate decomposition. The released CH 4 molecules are absorbed by the microporous solid, whereas water is retained at the surfaces of hydrophobic silicalite and forms a meniscus in the interlayer space. Methane uptake reaches 70% of the silicalite sorption capacity. The energy necessary for the endothermic MH dissociation is supplied by the exothermic methane absorption by the zeolite.

Zeolite based microconcentrators for volatile organic compounds sensing at trace-level: fabrication and performance

NASA Astrophysics Data System (ADS)

Almazán, Fernando; Pellejero, Ismael; Morales, Alberto; Urbiztondo, Miguel A.; Sesé, Javier; Pina, M. Pilar; Santamaría, Jesús

2016-08-01

A novel 6-step microfabrication process is proposed in this work to prepare microfluidic devices with integrated zeolite layers. In particular, microfabricated preconcentrators designed for volatile organic compounds (VOC) sensing applications are fully described. The main novelty of this work is the integration of the pure siliceous MFI type zeolite (silicalite-1) polycrystalline layer, i.e. 4.0  ±  0.5 μm thick, as active phase, within the microfabrication process just before the anodic bonding step. Following this new procedure, Si microdevices with an excellent distribution of the adsorbent material, integrated resistive heaters and Pyrex caps have been obtained. Firstly, the microconcentrator performance has been assessed by means of the normal hexane breakthrough curves as a function of sampling and desorption flowrates, temperature and micropreconcentrator design. In a step further, the best preconcentrator device has been tested in combination with downstream Si based microcantilevers deployed as VOC detectors. Thus, a preliminar evaluation of the improvement on detection sensitivity by silicalite-1 based microconcentrators is presented.

Experimental evidence of six-fold oxygen coordination for phosphorus and XANES calculations

NASA Astrophysics Data System (ADS)

Flank, A.-M.; Trcera, N.; Brunet, F.; Itié, J.-P.; Irifune, T.; Lagarde, P.

2009-11-01

Phosphorus, a group V element, has always been found so far in minerals, biological systems and synthetic compounds with an oxygen coordination number of four (i.e, PO4 groups). We demonstrate here using phosphorus K-edge XANES spectroscopy that this element can also adopt a six-fold oxygen coordination (i.e, PO6 groups). This new coordination was achieved in AlPO4 doped SiO2 stishovite synthesized at 18 GPa and 1873 K and quenched down to ambient conditions. The well-crystallized P-bearing stishovite grains (up to 100μm diameter) were embedded in the back-transformation products of high pressure form of AlPO4 matrix. They were identified by elemental mapping (μ-XRF). μ-XANES spectra collected at the Si and P K edges in the Si rich region with a very low concentration of P present striking resemblance, Si itself being characteristic of pure stishovite. We can therefore infer that phosphorus in the corresponding stishovite crystal is involved in an octahedral coordination made of six oxygen atoms. First principle XANES calculations using a plane-wave density functional formalism with core-hole effects treated in a supercell approach at the P K edge for a P atom substituting an Si one in the stishovite structure confirm this assertion. This result shows that in the lower-mantle where all silicon is six-fold coordinated, phosphorus has the crystal-chemical ability to remain incorporated into silicate structures.

Dynamics of confined reactive water in smectite clay-zeolite composites.

PubMed

Pitman, Michael C; van Duin, Adri C T

2012-02-15

The dynamics of water confined to mesoporous regions in minerals such as swelling clays and zeolites is fundamental to a wide range of resource management issues impacting many processes on a global scale, including radioactive waste containment, desalination, and enhanced oil recovery. Large-scale atomic models of freely diffusing multilayer smectite particles at low hydration confined in a silicalite cage are used to investigate water dynamics in the composite environment with the ReaxFF reactive force field over a temperature range of 300-647 K. The reactive capability of the force field enabled a range of relevant surface chemistry to emerge, including acid/base equilibria in the interlayer calcium hydrates and silanol formation on the edges of the clay and inner surface of the zeolite housing. After annealing, the resulting clay models exhibit both mono- and bilayer hydration structures. Clay surface hydration redistributed markedly and yielded to silicalite water loading. We find that the absolute rates and temperature dependence of water dynamics compare well to neutron scattering data and pulse field gradient measures from relevant samples of Ca-montmorillonite and silicalite, respectively. Within an atomistic, reactive context, our results distinguish water dynamics in the interlayer Ca(OH)(2)·nH(2)O environment from water flowing over the clay surface, and from water diffusing within silicalite. We find that the diffusion of water when complexed to Ca hydrates is considerably slower than freely diffusing water over the clay surface, and the reduced mobility is well described by a difference in the Arrhenius pre-exponential factor rather than a change in activation energy.

The highly selective oxidation of cyclohexane to cyclohexanone and cyclohexanol over VAlPO4 berlinite by oxygen under atmospheric pressure.

PubMed

Hong, Yun; Sun, Dalei; Fang, Yanxiong

2018-04-04

The oxidation of cyclohexane under mild conditions occupies an important position in the chemical industry. A few soluble transition metals were widely used as homogeneous catalysts in the industrial oxidation of cyclohexane. Because heterogeneous catalysts are more manageable than homogeneous catalysts as regards separation and recycling, in our study, we hydrothermally synthesized and used pure berlinite (AlPO 4 ) and vanadium-incorporated berlinite (VAlPO 4 ) as heterogeneous catalysts in the selective oxidation of cyclohexane with molecular oxygen under atmospheric pressure. The catalysts were characterized by means of by XRD, FT-IR, XPS and SEM. Various influencing factors, such as the kind of solvents, reaction temperature, and reaction time were investigated systematically. The XRD characterization identified a berlinite structure associated with both the AlPO 4 and VAlPO 4 catalysts. The FT-IR result confirmed the incorporation of vanadium into the berlinite framework for VAlPO 4 . The XPS measurement revealed that the oxygen ions in the VAlPO 4 structure possessed a higher binding energy than those in V 2 O 5 , and as a result, the lattice oxygen was existed on the surface of the VAlPO 4 catalyst. It was found that VAlPO 4 catalyzed the selective oxidation of cyclohexane with molecular oxygen under atmospheric pressure, while no activity was detected on using AlPO 4 . Under optimum reaction conditions (i.e. a 100 mL cyclohexane, 0.1 MPa O 2 , 353 K, 4 h, 5 mg VAlPO 4 and 20 mL acetic acid solvent), a selectivity of KA oil (both cyclohexanol and cyclohexanone) up to 97.2% (with almost 6.8% conversion of cyclohexane) was obtained. Based on these results, a possible mechanism for the selective oxidation of cyclohexane over VAlPO 4 was also proposed. As a heterogeneous catalyst VAlPO 4 berlinite is both high active and strong stable for the selective oxidation of cyclohexane with molecular oxygen. We propose that KA oil is formed via a catalytic cycle, which involves activation of the cyclohexane by a key active intermediate species, formed from the nucleophilic addition of the lattice oxygen ion with the carbon in cyclohexane, as well as an oxygen vacancy formed at the VAlPO 4 catalyst surface.

NOVEL SYNTHETIC METHOD FOR NARROW DISTRIBUTED COLLOIDAL SILICALITE

EPA Science Inventory

Preparation of zeolites is important for a variety of applications such as microelectronics, separation agents, ion exchange, catalysis, adsorbents, nanocomposites and zeolite membranes. Silicalite-1 is a crystalline, microporous polymorph of silicon dioxide with the MFI framewo...

Examining the Effectiveness of an Academic Language Planning Organizer as a Tool for Planning Science Academic Language Instruction and Supports

NASA Astrophysics Data System (ADS)

Jung, Karl G.; Brown, Julie C.

2016-12-01

To engage in the practices of science, students must have a strong command of science academic language. However, content area teachers often make academic language an incidental part of their lesson planning, which leads to missed opportunities to enhance students' language development. To support pre-service elementary science teachers (PSTs) in making language planning an explicit part of their science lessons, we created the Academic Language Planning Organizer (ALPO). The purpose of this study was to determine the effectiveness of the ALPO on two levels: first, by examining participants' interactions with the ALPO as they identified academic language features, objectives and supports; and second, by exploring the ways that participants translated identified language supports to planned science activities. Findings indicated that, when using the ALPO, PSTs identified clear language functions and relevant vocabulary terms, and also frequently developed clear, observable and measurable language objectives. When lesson planning, PSTs were largely successful in translating previously identified language supports to their lesson plans, and often planned additional language supports beyond what was required. We also found, however, that the ALPO did not meet its intended use in supporting PSTs in identifying discourse and syntax demands associated with specific academic language functions, suggesting that revisions to the ALPO could better support PSTs in identifying these academic language demands. Implications for supporting PSTs' planning for and scaffolding of science academic language use are presented.

Development of Silicalite/Glucose Oxidase-Based Biosensor and Its Application for Glucose Determination in Juices and Nectars

NASA Astrophysics Data System (ADS)

Dudchenko, Oleksandr Ye; Pyeshkova, Viktoriya M.; Soldatkin, Oleksandr O.; Akata, Burcu; Kasap, Berna O.; Soldatkin, Alexey P.; Dzyadevych, Sergei V.

2016-02-01

The application of silicalite for improvement of enzyme adsorption on new stainless steel electrodes is reported. Glucose oxidase (GOx) was immobilized by two methods: cross-linking by glutaraldehyde (GOx-GA) and cross-linking by glutaraldehyde along with GOx adsorption on silicalite-modified electrode (SME) (GOx-SME-GA). The GOx-SME-GA biosensors were characterized by a four- to fivefold higher sensitivity than GOx-GA biosensor. It was concluded that silicalite together with GA sufficiently enhances enzyme adhesion on stainless steel electrodes. The developed GOx-SME-GA biosensors were characterized by good reproducibility of biosensor preparation (relative standard deviation (RSD)—18 %), improved signal reproducibility (RSD of glucose determination was 7 %), and good storage stability (29 % loss of activity after 18-day storage). A series of fruit juices and nectars was analyzed using GOx-SME-GA biosensor for determination of glucose concentration. The obtained results showed good correlation with the data of high-performance liquid chromatography (HPLC) ( R = 0.99).

Mineralogy and Geochemistry of Vanadium-Bearing Black Shales at Zhangcun and Zhengfang, Eastern Jiangxi Province, China

NASA Astrophysics Data System (ADS)

Long, H.; Long, H.; Nekvasil, H.; Liu, Y.

2001-12-01

As a member of Hetang Formation, lower Cambrian, the Zhangcun-Zhengfang vanadium-bearing black shales are spread in the sea basin outside of the Ancient Jiangnan Island Arc. The composition of black shales is silicalite + siltstone + detrital carbonate. A large amount of hyalophane has been discovered in the shales and the hyalophane-rich rock is the major type of vanadium-host rock. The barium content in the hyalophane is up to 18.91%. The vanadium mainly exists in vanadiferous illite and several Ti-V oxides, possibly including a new mineral. The chemical formula of this kind of Ti-V oxide is V2O3¡nTiO2, n=4¡ª9, according to the electronic microprobe studies. The micro X-ray diffraction studies show the new mineral may be triclinic. The shales are rich in Ba, K, V and contain only trace Na and Mn while all the compositions of the shales except carbonate have a low content of Mg and Ca. According to the authors¡_ study, V obviously has a relationship with Ba and Se, which are from the volcano or hydrothermal activities, and the basic elements Cr, Co, Ni, Ti and Fe. It may present that they are from the same source. Thus, it seems that they are not from the ¡rnormal¡_ sedimentary environment and may be from the hydrothermal deposition. The REE models show that silicalite may be the hydrothermal deposit that does not mix with seawater while the REE models of hyalopahne-rich rock is similar to some modern hydrothermal deposits in the seafloor. The subtle negative anomaly of Yb may reflect the REE model of basalt in the seafloor. The geology and geochemistry of the shales indicate that the shales may be of hydrothermal genesis. Silicalite may be the typical ¡r pure¡_ hydrothermal sediment and hyalophane-rich rock may be the product of hydrothermal activity while the hydrothermal fluid passes the continent source material in the sedimentary process. V, Ti, Ba and Si may be from the volcanic rock in the seafloor and the Al and K may be from the continent.

Unfinished business: the rebirth of the ALPO Lunar Dome Survey

NASA Astrophysics Data System (ADS)

Huddleston, Marvin W.

2004-05-01

The ALPO board of directors approved the revival of the Lunar Dome Survey during their annual board meeting in the summer of 2003. The initial LDS program was conceived by Harry Jamieson in the early 1960's and headed by him when the British Astronomical Assn. (BAA) was invited to join the program, which they did. The joint effort between the ALPO and BAA lunar sections lasted for approximately 14 years, ending officially around 1976 due to a decline in interest. The program was again revived in 1987 under the direction of Jim Phillips and lasted until the mid-1990's. All told, this program has been one of the longest running programs in the history of the Lunar Section of ALPO. The revived program will concentrate on cleaning up the existing catalog, classification and confirmation of the objects contained therein, and analysis of the database created in the process. It is hoped that, as in the past, much of the newly revived Lunar Dome Survey will be an international effort.

Clean Transformation of Ethanol to Useful Chemicals. The Behavior of a Gold-Modified Silicalite Catalyst.

PubMed

Falletta, Ermelinda; Rossi, Michele; Teles, Joaquim Henrique; Della Pina, Cristina

2016-03-19

Upon addition of gold to silicalite-1 pellets (a MFI-type zeolite), the vapor phase oxidation of ethanol could be addressed to acetaldehyde or acetic acid formation. By optimizing the catalyst composition and reaction conditions, the conversion of ethanol could be tuned to acetaldehyde with 97% selectivity at 71% conversion or to acetic acid with 78% selectivity at total conversion. Considering that unloaded silicalite-1 was found to catalyze the dehydration of ethanol to diethylether or ethene, a green approach for the integrated production of four important chemicals is herein presented. This is based on renewable ethanol as a reagent and a modular catalytic process.

Adsorption interaction in the molecular hydrogen-aluminophosphate AlPO-5 zeolite system

NASA Astrophysics Data System (ADS)

Grenev, I. V.; Gavrilov, V. Yu.

2015-03-01

The adsorption interaction between molecular hydrogen and atoms forming the lattice of AlPO-5 zeolite is studied. The potential of intramolecular interaction is calculated by summing the potentials of individual pairwise H2-O(Al, P) interactions in a fragment of the zeolite structure with a volume of ˜32 nm3. Isopotential surfaces are constructed that allow determination of the shape of zeolite microchannels and the places of the preferential localization of sorbate molecules in the porous space. The calculated and experimental values of the Henry constant of H2 adsorption on AlPO-5 at 77 K are compared.

A new route for the synthesis of titanium silicalite-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vasile, Aurelia, E-mail: aurelia_vasile@yahoo.com; Busuioc-Tomoiaga, Alina Maria; Catalysis Research Department, ChemPerformance SRL, Iasi 700337

2012-01-15

Graphical abstract: Well-prepared TS-1 was synthesized by an innovative procedure using inexpensive reagents such as fumed silica and TPABr as structure-directing agent. This is the first time when highly crystalline TS-1 is obtained in basic medium, using sodium hydroxide as HO{sup -} ion source required for the crystallization process. Hydrolysis of titanium source has been prevented by titanium complexation with acetylacetone before structuring gel. Highlights: Black-Right-Pointing-Pointer TS-1 was obtained using cheap reagents as fumed silica and tetrapropylammonium bromide. Black-Right-Pointing-Pointer First time NaOH was used as source of OH{sup -} ions required for crystallization process. Black-Right-Pointing-Pointer The hydrolysis Ti alkoxides wasmore » controlled by Ti complexation with 2,4-pentanedione. -- Abstract: A new and efficient route using inexpensive reagents such as fumed silica and tetrapropylammonium bromide is proposed for the synthesis of titanium silicalite-1. High crystalline titanium silicalite-1 was obtained in alkaline medium, using sodium hydroxide as HO{sup -} ion source required for the crystallization process. Hydrolysis of titanium source with formation of insoluble oxide species was prevented by titanium complexation with before structuring gel. The final solids were fully characterized by powder X-ray diffraction, scanning electron microscopy, Fourier transform infrared, ultraviolet-visible diffuse reflectance, Raman and atomic absorption spectroscopies, as well as nitrogen sorption analysis. It was found that a molar ratio Ti:Si of about 0.04 in the initial reaction mixture is the upper limit to which well formed titanium silicalite-1 with channels free of crystalline or amorphous material can be obtained. Above this value, solids with MFI type structure containing both Ti isomorphously substituted in the network and extralattice anatase nanoparticles inside of channels is formed.« less

Calculating the permeability coefficients of mixed matrix membranes of polydimethylsiloxane and silicalite crystals to various ethanol-water solutions using molecular simulations.

EPA Science Inventory

The permeability coefficients of mixed matrix membranes of polydimethylsiloxane (PDMS) and silicalite crystal are taken as the sum of the permeability coefficients of membrane components each weighted by their associated mass fraction. The permeability coefficient of a membrane c...

Pervaporation behavior and integrated process for concentrating lignocellulosic ethanol through polydimethylsiloxane (PDMS) membrane.

PubMed

Chen, Jingwen; Zhang, Hongman; Wei, Ping; Zhang, Lin; Huang, He

2014-02-01

The effects of by-products from ethanol fermentation and hydrolysates of lignocelluloses on ethanol diffusion through polydimethylsiloxane (PDMS) membranes with/without silicalite-1 were investigated. A pervaporation process was integrated with lignocellulosic fermentation to concentrate bioethanol using bare PDMS membranes. Results showed that yeasts, solid particles, and salts increased ethanol flux and selectivity through the membranes (PDMS with/without silicalite-1), whereas glucose exerted negative effects on the performance. On bare PDMS membrane, the performance was not obviously affected by the existence of aliphatic acids. However, on PDMS-silicalite-1 membrane, a remarkable decrease in ethanol selectivity and a rapid growth of total flux in the presence of aliphatic acids were observed. These phenomena were due to the interaction of acids with silanol (Si-OH) groups to break the dense membrane surface. On the PDMS membranes with/without silicalite-1, degradation products of lignocellulosic hydrolysates such as furfural and hydroxyacetone slightly influenced separation performance. These results revealed that an integrated process can effectively eliminate product inhibition, improve ethanol productivity, and enhance the glucose conversion rate.

Molecular Simulations of Adsorption and Diffusion in Silicalite.

NASA Astrophysics Data System (ADS)

Snurr, Randall Quentin

The adsorption and diffusion of hydrocarbons in the zeolite silicalite have been studied using molecular simulations. The simulations use an atomistic description of zeolite/sorbate interactions and are based on principles of statistical mechanics. Emphasis was placed on developing new simulation techniques to allow complex systems relevant to industrial applications in catalysis and separations processes to be studied. Adsorption isotherms and heats of sorption for methane in silicalite were calculated from grand canonical Monte Carlo (GCMC) simulations and also from molecular dynamics (MD) simulations accompanied by Widom test particle insertions. Good agreement with experimental data from the literature was found. The adsorption thermodynamics of aromatic species in silicalite at low loading was predicted by direct evaluation of the configurational integrals. Good agreement with experiment was obtained for the Henry's constants and the heats of adsorption. Molecules were predicted to be localized in the channel intersections at low loading. At higher loading, conventional GCMC simulations were found to be infeasible. Several variations of the GCMC technique were developed incorporating biased insertion moves. These new techniques are much more efficient than conventional GCMC and allow for the prediction of adsorption isotherms of tightly-fitting aromatic molecules in silicalite. Our simulations when combined with experimental evidence of a phase change in the zeolite structure at intermediate loading provide an explanation of the characteristic steps seen in the experimental isotherms. A hierarchical atomistic/lattice model for studying these systems was also developed. The hierarchical model is more than an order of magnitude more efficient computationally than direct atomistic simulation. Diffusion of benzene in silicalite was studied using transition-state theory (TST). Such an approach overcomes the time-scale limitations of using MD simulations for studying sorbate dynamics. Predicted diffusion coefficients were found to be too low compared to experiment. This was attributed to the assumption of a rigid zeolite structure in the calculations and the use of a harmonic approximation for calculating the TST rate constants. Details of sorbate motion were also investigated.

Fabrication of MTN-type zeolite by self-assembling of supramolecular compound

NASA Astrophysics Data System (ADS)

Huang, Aisheng; Caro, Jürgen

2009-10-01

MTN-type (Zeolite Socony Mobil Thirty-Nine) zeolite was prepared at 473 K by a novel method through self-assembling of a supramolecular compound called 2,4,6-tris (4-pyridyl) triazine (TPT) in DMF (N,N-dimethylformamide). The effects of fluoride, DMF and germanium on the synthesis of MTN-type zeolite were investigated. The crystallization was facilitated by adding fluoride to the synthesis solution, resulting in the formation of highly crystalline MTN samples, while some amorphous phase was observed in fluoride-free batches. DMF was required to obtain a highly crystalline MTN sample, since TPT dissolves easier in DMF than in water, thus facilitating the self-assembling of TPT into a 3D network to structure the MTN framework. The MTN structure could be synthesized at low germanium content (Ge/Si≤0.18), while AST (AlPO 4-sixteen) as a foreign phase is formed at high germanium substitution (Ge/Si≥0.5).

Design and fabrication of zeolite macro- and micromembranes

NASA Astrophysics Data System (ADS)

Chau, Lik Hang Joseph

2001-07-01

The chemical nature of the support surface influences zeolite nucleation, crystal growth and elm adhesion. It had been demonstrated that chemical modification of support surface can significantly alter the zeolite film and has a good potential for large-scale applications for zeolite membrane production. The incorporation of titanium and vanadium metal ions into the structural framework of MFI zeolite imparts the material with catalytic properties. The effects of silica and metal (i.e., Ti and V) content, template concentration and temperature on the zeolite membrane growth and morphology were investigated. Single-gas permeation experiments were conducted for noble gases (He and Ar), inorganic gases (H2, N2, SF6) and hydrocarbons (methane, n-C4, i-C4) to determine the separation performance of these membranes. Using a new fabrication method based on microelectronic fabrication and zeolite thin film technologies, complex microchannel geometry and network (<5 mum), as well as zeolite arrays (<10 mum) were successfully fabricated onto highly orientated supported zeolite films. The zeolite micropatterns were stable even after repeated thermal cycling between 303 K and 873 K for prolonged periods of time. This work also demonstrates that zeolites (i.e., Sil-1, ZSM-5 and TS-1) can be employed as catalyst, membrane or structural materials in miniature chemical devices. Traditional semiconductor fabrication technology was employed in micromachining the device architecture. Four strategies for the manufacture of zeolite catalytic microreactors were discussed: zeolite powder coating, uniform zeolite film growth, localized zeolite growth, and etching of zeolite-silicon composite film growth inhibitors. Silicalite-1 was also prepared as free-standing membrane for zeolite membrane microseparators.

Report on the ALPO LTP observing program. [for establishing albedo scale for lunar features

NASA Technical Reports Server (NTRS)

Cameron, W. S.

1974-01-01

Observations of lunar transient phenomena for the Association of Lunar and Planetary Observers (ALPO) are reported. The procedures for making visual observations for estimating albedo are described, and the reported albedo analyzed for lunar topographic features. It is shown that a catalog or scale of albedos can be established for each feature.

Gradient-index elements made from phosphate glasses in the system Al(PO3)3 - Na2O - Ag2O by ion-exchange process

NASA Astrophysics Data System (ADS)

Staronski, Leszek R.; Wychowaniec, Marek; Wasylak, Jan

1994-10-01

Silver aluminum phosphate glassed have been tested as a material for gradient index (GRIN) elements fabrication by exchange of Na+ ions from mixed molten salt baths by the Ag+ ones. The annealing technique was used to control the final gradient and GRIN rod elements with radial index profile were prepared with n(r) equals no(1 - A/2 (DOT) rn) where 2

An Ultrahigh CO2-Loaded Silicalite-1 Zeolite: Structural Stability and Physical Properties at High Pressures and Temperatures.

PubMed

Marqueño, Tomas; Santamaria-Perez, David; Ruiz-Fuertes, Javier; Chuliá-Jordán, Raquel; Jordá, Jose L; Rey, Fernando; McGuire, Chris; Kavner, Abby; MacLeod, Simon; Daisenberger, Dominik; Popescu, Catalin; Rodriguez-Hernandez, Placida; Muñoz, Alfonso

2018-06-04

We report the formation of an ultrahigh CO 2 -loaded pure-SiO 2 silicalite-1 structure at high pressure (0.7 GPa) from the interaction of empty zeolite and fluid CO 2 medium. The CO 2 -filled structure was characterized in situ by means of synchrotron powder X-ray diffraction. Rietveld refinements and Fourier recycling allowed the location of 16 guest carbon dioxide molecules per unit cell within the straight and sinusoidal channels of the porous framework to be analyzed. The complete filling of pores by CO 2 molecules favors structural stability under compression, avoiding pressure-induced amorphization below 20 GPa, and significantly reduces the compressibility of the system compared to that of the parental empty one. The structure of CO 2 -loaded silicalite-1 was also monitored at high pressures and temperatures, and its thermal expansivity was estimated.

The application of silicalite-1/fly ash cenosphere (S/FAC) zeolite composite for the adsorption of methyl tert-butyl ether (MTBE).

PubMed

Lu, Jia; Xu, Fang; Wang, Deju; Huang, Jue; Cai, Weimin

2009-06-15

Silicalite-1/fly ash cenosphere (S/FAC) zeolite composite has been applied for batch adsorption of methyl tert-butyl ether (MTBE) from water systems. Here the key experimental conditions, including the ratio of initial MTBE concentration to the amount weight of S/FAC, adsorption time and temperature, have been discussed in detail. The results show that approximately 93-95% MTBE could be adsorbed with initial concentration of MTBE solution 1000 microg l(-1). The column flow-through experiments also prove the high capacity of S/FAC composite for MTBE removal. The distinct advantages of S/FAC zeolite composite as adsorbent lie in (1) enhanced adsorption rate and capacity based on hierarchical micro and meso/macroporosity of S/FAC; (2) more easily operation and recycling process by assembly of nano-sized silicalite-1 zeolite on FAC support.

Studies of redox active silicalite-2 and the development of stable white-light phosphors

NASA Astrophysics Data System (ADS)

Lita, Adrian

Mn-silicalite-2 was synthesized at high pH using the molecular cluster, Mn12O12(O2CCH3)16 as a Mn Source. No precipitation of manganese hydroxide was observed with this cluster even with the use of tetrabutylammonium hydroxide as a templating agent. This synthetic approach resulted in the incorporation of up to 2.5 mol % Mn into the silicalite-2 with direct substitution into the framework verified by a linear relationship between unit cell volume and loading. The Mn is reduced to Mn(II) during hydrothermal synthesis and incorporated into the silicalite-2 framework during calcination at 500°C. Further calcination at 750°C does not affect the crystallinity but oxidizes essentially all of the Mn(II) to Mn(III). Cr(IV) substituted silicalite-2 was generated by reduction of Cr(VI)-silicalite-2 lattice sites at in a CO atmosphere. The reduction process, Reduction at high pressures was found to give almost complete conversion of the Cr(VI) sites to Cr(IV). As generated, the Cr(IV) sites do not reoxidize to Cr(VI) under ambient conditions or in the presence of oxidants under reaction conditions. We report the development of new class solid-state white-light phosphors based on stable nanoparticle-silica glass composites. These materials are made from the incorporating of CdSe nanoparticles into a silica Sol-gel solution. Once it gelled and aged the materials are calcined at 500°C under oxygen. The solid that results are robust with a bright white luminescence (20%) under UV excitation that gives virtually pure white light with coordinates of (0.34, 0.36) on the CIE 1931 chromaticity diagram and, more importantly, the emission envelope coincides nearly identically with the scotopic eye response function. The white-light phosphors have a scotopic/phtopic ratio of 2.56, indicating that these phosphors will be perceived as a particularly efficient illumination source in a dark environment thereby being more energy efficient. The emission comes from a distribution of nanoscale CdSe particles, with size-polydispersity brought on by calcination and subsequent fusing of nanoparticle agglomerates in the micropores of the silica xerogel. The silica matrix makes them exceedingly robust, with no changes in the emission properties observed for periods in excess of 18 months.

Thermal stability of the Mobil Five type metallosilicate molecular sieves-An in situ high temperature X-ray diffraction study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhange, D.S.; Ramaswamy, Veda

2007-05-03

We have carried out in situ high temperature X-ray diffraction (HTXRD) studies of silicalite-1 (S-1) and metallosilicate molecular sieves containing iron, titanium and zirconium having Mobil Five (MFI) structure (iron silicalite-1 (FeS-1), titanium silicalite-1 (TS-1) and zirconium silicalite-1 (ZrS-1), respectively) in order to study the thermal stability of these materials. Isomorphous substitution of Si{sup 4+} by metal atoms is confirmed by the expansion of unit cell volume by X-ray diffraction (XRD) and the presence of Si-O-M stretching band at {approx}960 cm{sup -1} by Fourier transform infrared (FTIR) spectroscopy. Appearance of cristobalite phase is seen at 1023 and 1173 K inmore » S-1 and FeS-1 samples. While the samples S-1 and FeS-1 decompose completely to cristobalite at 1173 and 1323 K, respectively, the other two samples are thermally stable upto 1623 K. This transformation is irreversible. Although all materials show a negative lattice thermal expansion, their lattice thermal expansion coefficients vary. The thermal expansion behavior in all samples is anisotropic with relative strength of contraction along 'a' axes is more than along 'b' and 'c' axes in S-1, TS-1, ZrS-1 and vice versa in FeS-1. Lattice thermal expansion coefficients ({alpha} {sub v}) in the temperature range 298-1023 K were -6.75 x 10{sup -6} K{sup -1} for S-1, -12.91 x 10{sup -6} K{sup -1} for FeS-1, -16.02 x 10{sup -6} K{sup -1} for TS-1 and -17.92 x 10{sup -6} K{sup -1} for ZrS-1. The highest lattice thermal expansion coefficients ({alpha} {sub v}) obtained were -11.53 x 10{sup -6} K{sup -1} for FeS-1 in temperature range 298-1173 K, -20.86 x 10{sup -6} K{sup -1} for TS-1 and -25.54 x 10{sup -6} K{sup -1} for ZrS-1, respectively, in the temperature range 298-1623 K. Tetravalent cation substitution for Si{sup 4+} in the lattice leads to a high thermal stability as compared to substitution by trivalent cations.« less

Biochemical evolution. I. Polymerization on internal, organophilic silica surfaces of dealuminated zeolites and feldspars

PubMed Central

Smith, Joseph V.

1998-01-01

Catalysis at mineral surfaces might generate replicating biopolymers from simple chemicals supplied by meteorites, volcanic gases, and photochemical gas reactions. Many ideas are implausible in detail because the proposed mineral surfaces strongly prefer water and other ionic species to organic ones. The molecular sieve silicalite (Union Carbide; = Al-free Mobil ZSM-5 zeolite) has a three-dimensional, 10-ring channel system whose electrically neutral Si-O surface strongly adsorbs organic species over water. Three -O-Si tetrahedral bonds lie in the surface, and the fourth Si-O points inwards. In contrast, the outward Si-OH of simple quartz and feldspar crystals generates their ionic organophobicity. The ZSM-5-type zeolite mutinaite occurs in Antarctica with boggsite and tschernichite (Al-analog of Mobil Beta). Archean mutinaite might have become de-aluminated toward silicalite during hot/cold/wet/dry cycles. Catalytic activity of silicalite increases linearly with Al-OH substitution for Si, and Al atoms tend to avoid each other. Adjacent organophilic and catalytic Al-OH regions in nanometer channels might have scavenged organic species for catalytic assembly into specific polymers protected from prompt photochemical destruction. Polymer migration along weathered silicic surfaces of micrometer-wide channels of feldspars might have led to assembly of replicating catalytic biomolecules and perhaps primitive cellular organisms. Silica-rich volcanic glasses should have been abundant on the early Earth, ready for crystallization into zeolites and feldspars, as in present continental basins. Abundant chert from weakly metamorphosed Archaean rocks might retain microscopic clues to the proposed mineral adsorbent/catalysts. Other framework silicas are possible, including ones with laevo/dextro one-dimensional channels. Organic molecules, transition-metal ions, and P occur inside modern feldspars. PMID:9520372

Biochemical evolution. I. Polymerization On internal, organophilic silica surfaces of dealuminated zeolites and feldspars.

PubMed

Smith, J V

1998-03-31

Catalysis at mineral surfaces might generate replicating biopolymers from simple chemicals supplied by meteorites, volcanic gases, and photochemical gas reactions. Many ideas are implausible in detail because the proposed mineral surfaces strongly prefer water and other ionic species to organic ones. The molecular sieve silicalite (Union Carbide; = Al-free Mobil ZSM-5 zeolite) has a three-dimensional, 10-ring channel system whose electrically neutral Si-O surface strongly adsorbs organic species over water. Three -O-Si tetrahedral bonds lie in the surface, and the fourth Si-O points inwards. In contrast, the outward Si-OH of simple quartz and feldspar crystals generates their ionic organophobicity. The ZSM-5-type zeolite mutinaite occurs in Antarctica with boggsite and tschernichite (Al-analog of Mobil Beta). Archean mutinaite might have become de-aluminated toward silicalite during hot/cold/wet/dry cycles. Catalytic activity of silicalite increases linearly with Al-OH substitution for Si, and Al atoms tend to avoid each other. Adjacent organophilic and catalytic Al-OH regions in nanometer channels might have scavenged organic species for catalytic assembly into specific polymers protected from prompt photochemical destruction. Polymer migration along weathered silicic surfaces of micrometer-wide channels of feldspars might have led to assembly of replicating catalytic biomolecules and perhaps primitive cellular organisms. Silica-rich volcanic glasses should have been abundant on the early Earth, ready for crystallization into zeolites and feldspars, as in present continental basins. Abundant chert from weakly metamorphosed Archaean rocks might retain microscopic clues to the proposed mineral adsorbent/catalysts. Other framework silicas are possible, including ones with laevo/dextro one-dimensional channels. Organic molecules, transition-metal ions, and P occur inside modern feldspars.

Biosensors Based on Urease Adsorbed on Nickel, Platinum, and Gold Conductometric Transducers Modified with Silicalite and Nanozeolites

NASA Astrophysics Data System (ADS)

Kucherenko, Ivan S.; Soldatkin, Oleksandr O.; Kasap, Berna Ozansoy; Kurç, Burcu Akata; Melnyk, Volodymir G.; Semenycheva, Lyudmila M.; Dzyadevych, Sergei V.; Soldatkin, Alexei P.

This work describes urease-based conductometric biosensors that were created using nontypical method of urease immobilization via adsorption on micro- and nanoporous particles: silicalite and nanocrystalline zeolites Beta (BEA) and L. Conductometric transducers with nickel, gold, and platinum interdigitated electrodes were used. Active regions of the nickel transducers were modified with microparticles using two procedures—spin coating and drop coating. Gold and platinum transducers were modified with silicalite using drop coating since it was more effective. Scanning electron microscopy was used to evaluate effectiveness of these procedures. The procedure of spin coating produced more uniform layers of particles (and biosensors had good reproducibility of preparation), but it was more complicated, drop coating was easier and led to formation of a bulk of particles; thus, biosensors had bigger sensitivity but worse reproducibility of preparation. Urease was immobilized onto transducers modified with particles by physical adsorption. Analytical characteristics of the obtained biosensors for determination of urea (calibration curves, sensitivity, limit of detection, linear concentration range, noise of responses, reproducibility of signal during a day, and operational stability during 3 days) were compared. Biosensors with all three particles deposited by spin coating showed similar characteristics; however, silicalite was a bit more effective. Biosensors based on nickel transducers modified by drop coating had better characteristics in comparison with modification by spin coating (except reproducibility of preparation). Transducers with gold electrodes showed best characteristics while creating biosensors, platinum electrodes were slightly inferior to them, and nickel electrodes were the worst.

Light Helicopter Family Trade-Off Analysis. Volume 4. Appendix N

DTIC Science & Technology

1985-05-15

Figur«! N -V1I-9 through N -VII-U ahow th« futl flow CMp«rlsoas chac comt|>oad r.o th« powar r«qutr«««nt* thown by flguraa (J-VII-l through M-VII-4...HELICOPTER. FAMILY TRADE-OFF ANALYSIS APPENDIX N VOLUME IV ACN: 69396 • Copy l_Q] of 130 c:optea. 15 Nay 198S ~ .. 8 06 .0&1 OTIC ELECTE AU613...TITLE (- ..... do) I. TYPf ’!! ~POitT a PI!I’IOD COVI:IU!O LIGHT HELICOPTER FAMILY TRADE-OFF ANALYSIS, Fina t y Report, APPENDIX N , VOLUME IV of XI

Nanosized zeolites as a perspective material for conductometric biosensors creation

NASA Astrophysics Data System (ADS)

Kucherenko, Ivan; Soldatkin, Oleksandr; Kasap, Berna Ozansoy; Kirdeciler, Salih Kaan; Kurc, Burcu Akata; Jaffrezic-Renault, Nicole; Soldatkin, Alexei; Lagarde, Florence; Dzyadevych, Sergei

2015-05-01

In this work, the method of enzyme adsorption on different zeolites and mesoporous silica spheres (MSS) was investigated for the creation of conductometric biosensors. The conductometric transducers consisted of gold interdigitated electrodes were placed on the ceramic support. The transducers were modified with zeolites and MSS, and then the enzymes were adsorbed on the transducer surface. Different methods of zeolite attachment to the transducer surface were used; drop coating with heating to 200°C turned out to be the best one. Nanozeolites beta and L, zeolite L, MSS, and silicalite-1 (80 to 450 nm) were tested as the adsorbents for enzyme urease. The biosensors with all tested particles except zeolite L had good analytical characteristics. Silicalite-1 (450 nm) was also used for adsorption of glucose oxidase, acetylcholinesterase, and butyrylcholinesterase. The glucose and acetylcholine biosensors were successfully created, whereas butyrylcholinesterase was not adsorbed on silicalite-1. The enzyme adsorption on zeolites and MSS is simple, quick, well reproducible, does not require use of toxic compounds, and therefore can be recommended for the development of biosensors when these advantages are especially important.

A Fiber Optic Interferometric Sensor Platform for Determining Gas Diffusivity in Zeolite Films.

PubMed

Yang, Ruidong; Xu, Zhi; Zeng, Shixuan; Jing, Wenheng; Trontz, Adam; Dong, Junhang

2018-04-04

Fiber optic interferometer (FOI) sensors have been fabricated by directly growing pure-silica MFI-type zeolite (i.e., silicalite) films on straight-cut endfaces of single-mode communication optical fibers. The FOI sensor has been demonstrated for determining molecular diffusivity in the zeolite by monitoring the temporal response of light interference from the zeolite film during the dynamic process of gas adsorption. The optical thickness of the zeolite film depends on the amount of gas adsorption that causes the light interference to shift upon loading molecules into the zeolitic channels. Thus, the time-dependence of the optical signal reflected from the coated zeolite film can represent the adsorption uptake curve, which allows computation of the diffusivity using models derived from the Fick’s Law equations. In this study, the diffusivity of isobutane in silicalite has been determined by the new FOI sensing method, and the results are in good agreement with literature values obtained by various conventional macroscopic techniques. The FOI sensor platform, because of its robustness and small size, could be useful for studying molecular diffusion in zeolitic materials under conditions that are inaccessible to the existing techniques.

Interaction of water with (silico)aluminophosphate zeotypes: a comparative investigation using dispersion-corrected DFT.

PubMed

Fischer, Michael

2016-06-21

Porous aluminophosphates (AlPOs) and silicoaluminophosphates (SAPOs) with zeolite-like structures have received considerable attention as potential adsorbents for heat transformation applications using water adsorption/desorption cycles. Since a detailed experimental characterisation of the water adsorption properties has only been performed for some of these materials, such as AlPO-18 (AEI topology) and SAPO-34 (CHA topology), more systematic insights regarding the influence of the pore topology and (for SAPOs) the arrangement of the framework protons on the affinity towards water are lacking. To study the relationships between structure and properties in more detail, the interaction of water with six structurally different AlPOs (with AEI, AFX, CHA, ERI, GIS, RHO topologies) and their SAPO analogues was investigated using dispersion-corrected density-functional theory (DFT-D) calculations. Different possible locations of silicon atoms and charge-balancing protons were considered for the SAPO systems. The calculations for SAPOs at low water loadings (one H2O molecule per framework proton) revealed that the interaction energies exhibit a considerable variation, ranging from -75 to -100 kJ mol(-1) (per water molecule). The differences in interaction energy were rationalised with the different structural environment of the framework protons at which the water molecules are adsorbed. At high water uptakes (near saturation), interaction energies in the range of -65 kJ mol(-1) were obtained for all AlPOs, and there was no evidence for a marked influence of pore size and/or topology on the interaction strength. The interaction of water with SAPOs was found to be approximately 5 kJ mol(-1) stronger than for AlPOs due to an increased contribution of electrostatic interactions. An analysis of the structural changes upon water adsorption revealed striking differences between the distinct topologies, with the materials with GIS and RHO topologies being distorted much more drastically than the systems based on double six-ring (d6r) units. Moreover, the direct coordination of water molecules to framework aluminium atoms occurs more frequently in these materials, an observation that points towards a reduced structural stability upon hydration.

Reconstructing the microstructure of polyimide-silicalite mixed-matrix membranes and their particle connectivity using FIB-SEM tomography.

PubMed

Diblíková, P; Veselý, M; Sysel, P; Čapek, P

2018-03-01

Properties of a composite material made of a continuous matrix and particles often depend on microscopic details, such as contacts between particles. Focusing on processing raw focused-ion beam scanning electron microscope (FIB-SEM) tomography data, we reconstructed three mixed-matrix membrane samples made of 6FDA-ODA polyimide and silicalite-1 particles. In the first step of image processing, backscattered electron (BSE) and secondary electron (SE) signals were mixed in a ratio that was expected to obtain a segmented 3D image with a realistic volume fraction of silicalite-1. Second, after spatial alignment of the stacked FIB-SEM data, the 3D image was smoothed using adaptive median and anisotropic nonlinear diffusion filters. Third, the image was segmented using the power watershed method coupled with a seeding algorithm based on geodesic reconstruction from the markers. If the resulting volume fraction did not match the target value quantified by chemical analysis of the sample, the BSE and SE signals were mixed in another ratio and the procedure was repeated until the target volume fraction was achieved. Otherwise, the segmented 3D image (replica) was accepted and its microstructure was thoroughly characterized with special attention paid to connectivity of the silicalite phase. In terms of the phase connectivity, Monte Carlo simulations based on the pure-phase permeability values enabled us to calculate the effective permeability tensor, the main diagonal elements of which were compared with the experimental permeability. In line with the hypothesis proposed in our recent paper (Čapek, P. et al. (2014) Comput. Mater. Sci. 89, 142-156), the results confirmed that the existence of particle clusters was a key microstructural feature determining effective permeability. © 2017 The Authors Journal of Microscopy © 2017 Royal Microscopical Society.

Scintillation properties of rare-earth doped NaPO3-Al(PO3)3 glasses

NASA Astrophysics Data System (ADS)

Kuro, Tomoaki; Okada, Go; Kawaguchi, Noriaki; Fujimoto, Yutaka; Masai, Hirokazu; Yanagida, Takayuki

2016-12-01

We systematically investigated photoluminescence (PL), scintillation and dosimeter properties of rare-earth (RE) doped NaPO3-Al(PO3)3 (NAP) glasses. The NAP glasses doped with a series of RE ions (La-Yb, except Pm) with a consistent concentration (0.3 wt%) were prepared by the conventional melt-quenching method. The PL and scintillation decay time profiles showed fast (ns) and slow (μs or ms) components: the fast components from 15 to 100 ns were due to the host or 5d-4f transition emission, and the slow components from 15 μs to 5 ms were due to the 4f-4f transitions of RE. The thermally stimulated luminescence (TSL) was evaluated as a dosimeter property, and glow peaks appeared around 400 °C in all the samples. The TSL dose response function was examined in the dose range from 10 mGy to 10 Gy. Among the samples tested, Nd and Tb doped glasses showed higher signal by at least one order of magnitude than those of non-doped and other RE-doped samples. Over the dose range tested, the TSL signals are linearly related with the incident X-ray dose, showing a potential for practical applications.

Identification of HNF4A Mutation p.T130I and HNF1A Mutations p.I27L and p.S487N in a Han Chinese Family with Early-Onset Maternally Inherited Type 2 Diabetes.

PubMed

Yang, Ying; Zhou, Tai-Cheng; Liu, Yong-Ying; Li, Xiao; Wang, Wen-Xue; Irwin, David M; Zhang, Ya-Ping

2016-01-01

Maturity-onset diabetes of the young (MODY) is characterized by the onset of diabetes before the age of 25 years, positive family history, high genetic predisposition, monogenic mutations, and an autosomal dominant mode of inheritance. Here, we aimed to investigate the mutations and to characterize the phenotypes of a Han Chinese family with early-onset maternally inherited type 2 diabetes. Detailed clinical assessments and genetic screening for mutations in the HNF4α, GCK, HNF-1α, IPF-1, HNF1β, and NEUROD1 genes were carried out in this family. One HNF4A mutation (p.T130I) and two HNF1A polymorphisms (p.I27L and p.S487N) were identified. Mutation p.T130I was associated with both early-onset and late-onset diabetes and caused downregulated HNF4A expression, whereas HNF1A polymorphisms p.I27L and p.S487N were associated with the age of diagnosis of diabetes. We demonstrated that mutation p.T130I in HNF4A was pathogenic as were the predicted polymorphisms p.I27L and p.S487N in HNF1A by genetic and functional analysis. Our results show that mutations in HNF4A and HNF1A genes might account for this early-onset inherited type 2 diabetes.

Methods and Applications of Time Series Analysis. Part I. Regression, Trends, Smoothing, and Differencing.

DTIC Science & Technology

1980-07-01

FUNCTION ( t) CENTERED AT C WITH PERIOD n -nr 0 soTIME t FIGURE 3.4S RECTAPOOLAR PORN )=C FUNCTION g t) CENTERED AT 0 WITH PERIOD n n n 52n tI y I (h...of a typical family in Kabiria (a city in Northern Algeria) over the time period Jan.-Feb. 1975 through Nov.-Dec. 1977. We would like to obtain a...values of y .. .. ... -75- Table 4.2 The Average Bi-Monthly Expenses of a Family in Kabiria and Their Fourier Representation Fourier Coefficients x k

The Influence of Zeolites on Radical Formation During Lignin Pyrolysis.

PubMed

Bährle, Christian; Custodis, Victoria; Jeschke, Gunnar; van Bokhoven, Jeroen A; Vogel, Frédéric

2016-09-08

Lignin from lignocellulosic biomass is a promising source of energy, fuels, and chemicals. The conversion of the polymeric lignin to fuels and chemicals can be achieved by catalytic and noncatalytic pyrolysis. The influence of nonporous silica and zeolite catalysts, such as silicalite, HZSM5, and HUSY, on the radical and volatile product formation during lignin pyrolysis was studied by in situ high-temperature electron paramagnetic resonance spectroscopy (HTEPR) as well as GC-MS. Higher radical concentrations were observed in the samples containing zeolite compared to the sample containing only lignin, which suggests that there is a stabilizing effect by the inorganic surfaces on the formed radical fragments. This effect was observed for nonporous silica as well as for HUSY, HZSM5, and silicalite zeolite catalysts. However, the effect is far larger for the zeolites owing to their higher specific surface area. The zeolites also showed an effect on the volatile product yield and the product distribution within the volatile phase. Although silicalite showed no effect on the product selectivity, the acidic zeolites such as HZSM5 or HUSY increased the formation of deoxygenated products such as benzene, toluene, xylene (BTX), and naphthalene. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Interaction of human osteoblast-like Saos-2 cells with stainless steel coated by silicalite-1 films.

PubMed

Jirka, Ivan; Vandrovcová, Marta; Plšek, Jan; Bouša, Milan; Brabec, Libor; Dragounová, Helena; Bačáková, Lucie

2017-07-01

This paper investigates the interaction of human osteoblast-like Saos-2 cells with stainless steel covered by a film of densely inter-grown silicalite-1 crystals with defined outer and inner surfaces. The chemical composition of this film, labeled as SF(RT), was tuned by heat treatment at 300°C and 500°C (labeled as SF(300) and SF(500), respectively) and characterized by X-ray photoelectron spectroscopy (XPS), water drop contact angle (WCA) measurements and scanning electron microscopy (SEM). The number, the spreading area and the activity of alkaline phosphatase of human osteoblast-like Saos-2 cells in cultures on the silicalite-1 film were affected by the chemical composition of its outer surface and by its micro-porous structure. The number and the spreading area of the adhered osteoblast-like cells on day 1 was highest on the surface of SF(RT) relative to their adhesion and spreading on a glass cover slip due to the SF(RT) topology. However, SF(300) markedly supported cell growth during days 3 and 7 after seeding. Copyright © 2017 Elsevier B.V. All rights reserved.

Symmetry and topology code of the cluster self-assembly of framework MT structures of alumophosphates AlPO4(H2O)2 (metavariscite and variscite) and Al2(PO4)2(H2O)3 (APC)

NASA Astrophysics Data System (ADS)

Ilyushin, G. D.; Blatov, V. A.

2017-03-01

The supramolecular chemistry of alumophosphates, which form framework 3D MT structures from polyhedral AlO4(H2O)2 clusters with octahedral O coordination (of M polyhedra) and PO4 and AlO4 with tetrahedral O coordination (of T polyhedra), is considered. A combinatorial-topological modeling of the formation of possible types of linear (six types) and ring (two types) tetrapolyhedral cluster precursors M2T2 from MT monomers is carried out. Different versions of chain formation from linked (MT)2 rings (six types) are considered. The model, which has a universal character, has been used to simulate the cluster selfassembly of the crystal structure of AlPO4(H2O)2 minerals (metavariscite, m-VAR, and variscite, VAR) and zeolite [Al2(PO4)2(H2O)2] · H2O (APC). A tetrapolyhedral linear precursor is established for m-VAR and a ring precursor (MT)2 is established for VAR and APC. The symmetry and topology code of the processes of crystal structure self-assembly from cluster precursors is completely reconstructed. The functional role of the O-H···O hydrogen bonds is considered for the first time. The cluster self-assembly model explains the specific features of the morphogenesis of single crystals: m-VAR prisms, flattened VAR octahedra, and needleshaped APC square-base prisms.

The Contrasting Effects of Alum-Treated Chicken Manures and KH2PO4 on Phosphorus Behavior in Soils.

PubMed

Huang, Lidong; Yang, Junming; Xu, Yuting; Lei, Jiayan; Luo, Xiaoshan; Cade-Menun, Barbara J

2018-03-01

Alum [KAl(SO)⋅12HO] is often added to chicken manure to limit P solubility after land application. This is generally ascribed to the formation of Al-PO complexes. However, Al-PO complex formation could be affected by the matrix of chicken manure, which varies with animal diet. Alum was added to KHPO (as a reference material) and two manures from typical chicken farms in China, one from an intensive farm (CMIF) and another from free-ranging chickens (CMFR). These were subsequently incubated with soils for 100 d to investigate P transformations. Alum reduced water-soluble colorimetrically reactive phosphorus (RP) from soils amended with manure more effectively than in soils amended with KHPO. Alum addition lowered Mehlich-3 RP in soils with CMFR but had no influence on Mehlich-3 RP in CMIF- or KHPO-amended soils. A comparison of P in digested Mehlich-3 extracts with RP in undigested samples showed significantly increased P in digests of alum-treated CMFR only. Fractionation data indicated that alum treatment increased P in the NHF-RP (Al-P) fraction only in soils with KHPO, but not in soils with manure treatments. Furthermore, NaOH-extracted nonreactive P was markedly higher in soil with alum-treated CMFR relative to normal CMFR. The CMFR manure was assumed to contain higher concentrations of organic P because these chickens were fed grains only. These results suggest that the formation of alum-organic P complexes may reduce P solubility. By comparing alum-treated KHPO and manures, it appears that organic matter in manure could interfere with the formation of Al-PO complexes. Copyright © Her Majesty the Queen in Right of Canada, as represented by the Minister of Agriculture and AgriFood Canada.

Growth promotion of peanut (Arachis hypogaea L.) and maize (Zea mays L.) plants by single and mixed cultures of efficient phosphate solubilizing bacteria that are tolerant to abiotic stress and pesticides.

PubMed

Anzuay, María Soledad; Ciancio, María Gabriela Ruiz; Ludueña, Liliana Mercedes; Angelini, Jorge Guillermo; Barros, Germán; Pastor, Nicolás; Taurian, Tania

2017-06-01

The aims of this study were, to analyze in vitro phosphate solubilization activity of six native peanut bacteria and to determine the effect of single and mixed inoculation of these bacteria on peanut and maize plants. Ability to produce organic acids and cofactor PQQ, to solubilize FePO 4 and AlPO 4 and phosphatase activity were analyzed. Also, the ability to solubilize phosphate under abiotic stress and in the presence of pesticides of the selected bacteria was determined. The effect of single and mixed bacterial inocula was analyzed on seed germination, maize plant growth and in a crop rotation plant assay with peanut and maize. The six strains produced gluconic acid and five released cofactor PQQ into the medium. All bacteria showed ability to solubilize phosphate from FePO 4 and AlPO 4 and phosphatase activity. The ability of the bacteria to solubilize tricalcium phosphate under abiotic stress and in presence of pesticides indicated encouraging results. Bacterial inoculation on peanut and maize increased seed germination, plant́s growth and P content. Phosphate solubilizing bacteria used in this study showed efficient phosphate mineralizing and solubilization ability and would be potential P-biofertilizers for peanut and maize. Copyright © 2017 Elsevier GmbH. All rights reserved.

Influence of Crystal Expansion/Contraction on Zeolite Membrane Permeation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sorenson, Stephanie G; Payzant, E Andrew; Noble, Richard D

X-ray diffraction was used to measure the unit cell parameters of B-ZSM-5, SAPO-34, and NaA zeolite powders as a function of adsorbate loading at 303 K, and in one case, at elevated temperatures. Most adsorbates expanded the zeolite crystals below saturation loading at 303 K: n-hexane and SF6 in B-ZSM-5, methanol and CO2 in SAPO-34, and methanol in NaA zeolite. As the loadings increased, the crystals expanded more. Changes in the unit cell volumes of B-ZSM-5 and SAPO-34 zeolite powders correlated with changes in permeation through zeolite membranes defects. When the zeolite crystals expanded or contracted upon adsorption, the defectmore » sizes decreased or increased. In B-ZSM-5 membranes, the fluxes through defects decreased dramatically when n-hexane or SF6 adsorbed. In contrast, i-butane adsorption at 303 K contracted B-ZSM-5 crystals at low loadings and expanded them at higher loadings. Correspondingly, the flux through B-ZSM-5 membrane defects increased at low i-butane loadings and decreased at high loading because the defects increased in size at low loading and decreased at high loadings. At 398 K and 473 K, n-hexane expanded the B-ZSM-5 unit cell more as the temperature increased from 303 to 473 K. The silicalite-1 and B-ZSM-5 unit cell volumes expanded similarly upon n-hexane adsorption at 303 K; boron substitution had little effect on volume expansion.« less

Pervaporative stripping of acetone, butanol and ethanol to improve ABE fermentation.

PubMed

Jitesh, K; Pangarkar, V G; Niranjan, K

2000-01-01

Acetone-butanol-ethanol fermentation by anaerobic bacterium C. acetobutylicum is a potential source for feedstock chemicals. The problem of product induced inhibition makes this fermentation economically infeasible. Pervaporation is studied as an effective separation technique to remove the toxic inhibitory products. Various membranes like Styrene Butadiene Rubber (SBR), Ethylene Propylene Diene Rubber (EPDM), plain Poly Dimethyl Siloxane (PDMS) and silicalite filled PDMS were studied for the removal of acetone, butanol and ethanol, from binary aqueous mixtures and from a quaternary mixture. It was found that the overall performance of PDMS filled with 15% w/w of silicalite was the best for removal of butanol in binary mixture study. SBR performance was best for the quaternary mixture studied.

High-pressure-induced structural changes, amorphization and molecule penetration in MFI microporous materials: a review.

PubMed

Vezzalini, Giovanna; Arletti, Rossella; Quartieri, Simona

2014-06-01

This is a comparative study on the high-pressure behavior of microporous materials with an MFI framework type (i.e. natural mutinaite, ZSM-5 and the all-silica phase silicalite-1), based on in-situ experiments in which penetrating and non-penetrating pressure-transmitting media were used. Different pressure-induced phenomena and deformation mechanisms (e.g. pressure-induced over-hydration, pressure-induced amorphization) are discussed. The influence of framework and extra-framework composition and of the presence of silanol defects on the response to the high pressure of MFI-type zeolites is discussed.

Effect of gas adsorption on acoustic wave propagation in MFI zeolite membrane materials: experiment and molecular simulation.

PubMed

Manga, Etoungh D; Blasco, Hugues; Da-Costa, Philippe; Drobek, Martin; Ayral, André; Le Clezio, Emmanuel; Despaux, Gilles; Coasne, Benoit; Julbe, Anne

2014-09-02

The present study reports on the development of a characterization method of porous membrane materials which consists of considering their acoustic properties upon gas adsorption. Using acoustic microscopy experiments and atomistic molecular simulations for helium adsorbed in a silicalite-1 zeolite membrane layer, we showed that acoustic wave propagation could be used, in principle, for controlling the membranes operando. Molecular simulations, which were found to fit experimental data, showed that the compressional modulus of the composite system consisting of silicalite-1 with adsorbed He increases linearly with the He adsorbed amount while its shear modulus remains constant in a large range of applied pressures. These results suggest that the longitudinal and Rayleigh wave velocities (VL and VR) depend on the He adsorbed amount whereas the transverse wave velocity VT remains constant.

Further Evidence for Robust Familiality of Pediatric Bipolar-I Disorder: Results from a Very Large Controlled Family Study of Pediatric Bipolar-I Disorder and a Meta-Analysis

PubMed Central

Wozniak, Janet; Faraone, Stephen V.; Martelon, MaryKate; McKillop, Hannah N.; Biederman, Joseph

2013-01-01

Objective To determine the risk for BP-I disorder in first-degree relatives of children with DSM-IV bipolar-I disorder (BP-I) via meta-analysis and expanded controlled study. Data Sources and Extraction Meta-Analysis We searched the Pubmed database for scientific articles published in the world literature in the English language through 2011. The key words searched were: bipolar disorder, first-degree relatives, family study, control. All online abstracts were reviewed and relevant full manuscripts were collected and reviewed. Citations were also examined for other potential relevant articles. We included only controlled family studies that examined rates of bipolar-I disorder in all first-degree relatives (parents and siblings) of pediatric bipolar-I probands and included only studies that had age and sex matched controls. Family history studies were excluded. Also excluded were studies that were not in English, did not report the rates of all first-degree relatives, and reported only bipolar spectrum rates. We also excluded family studies that included only adult probands. We conducted a meta-analysis of the five controlled family studies of pediatric BP-I probands that met our search criteria using the random effects model of DerSimonian and Laird. Method Family Study We greatly expanded our previous sample of DSM-IV BP-I probands using structured diagnostic interviews. Our new study included 239 children satisfying full with DSM-IV diagnostic criteria for BP-I (n=726 first-degree relatives), 162 ADHD (without BP-I) probands (n=511 first-degree relatives), and 136 healthy control (without ADHD or BP-I) probands (n=411 first-degree relatives). We used the Kaplan-Meier cumulative failure function to calculate survival curves and cumulative, lifetime risk in relatives. Cox proportional hazard models were used to calculate the risk of BP-I in relatives. Results The pooled odds ratio for BP-I disorder in relatives was estimated to be 6.96 (95% Confidence Interval (CI): 4.8 to 10.1). We also found first-degree relatives of BP-I probands to be significantly more likely than first-degree relatives of both ADHD (Hazards Ratio: 3.02; 95% CI: 1.85 to 4.93; p<0.001) and control probands (HR: 2.83; 1.65 to 4.84; p<0.001) to have bipolar-I disorder. Conclusion Our results document an increased familial risk for BP-I disorder in relatives of pediatric probands with DSM-IV BP-I. PMID:23140652

New infinite families of exact sums of squares formulas, Jacobi elliptic functions, and Ramanujan's tau function.

PubMed

Milne, S C

1996-12-24

In this paper, we give two infinite families of explicit exact formulas that generalize Jacobi's (1829) 4 and 8 squares identities to 4n(2) or 4n(n + 1) squares, respectively, without using cusp forms. Our 24 squares identity leads to a different formula for Ramanujan's tau function tau(n), when n is odd. These results arise in the setting of Jacobi elliptic functions, Jacobi continued fractions, Hankel or Turánian determinants, Fourier series, Lambert series, inclusion/exclusion, Laplace expansion formula for determinants, and Schur functions. We have also obtained many additional infinite families of identities in this same setting that are analogous to the eta-function identities in appendix I of Macdonald's work [Macdonald, I. G. (1972) Invent. Math. 15, 91-143]. A special case of our methods yields a proof of the two conjectured [Kac, V. G. and Wakimoto, M. (1994) in Progress in Mathematics, eds. Brylinski, J.-L., Brylinski, R., Guillemin, V. & Kac, V. (Birkhäuser Boston, Boston, MA), Vol. 123, pp. 415-456] identities involving representing a positive integer by sums of 4n(2) or 4n(n + 1) triangular numbers, respectively. Our 16 and 24 squares identities were originally obtained via multiple basic hypergeometric series, Gustafson's C(l) nonterminating (6)phi(5) summation theorem, and Andrews' basic hypergeometric series proof of Jacobi's 4 and 8 squares identities. We have (elsewhere) applied symmetry and Schur function techniques to this original approach to prove the existence of similar infinite families of sums of squares identities for n(2) or n(n + 1) squares, respectively. Our sums of more than 8 squares identities are not the same as the formulas of Mathews (1895), Glaisher (1907), Ramanujan (1916), Mordell (1917, 1919), Hardy (1918, 1920), Kac and Wakimoto, and many others.

Radiation damage of variscite in historic crafts: Solarization, decolouration, structural changes and spectra from ionoluminescence

NASA Astrophysics Data System (ADS)

Garcia-Guinea, J.; Correcher, V.; Sanchez-Muñoz, L.; Lopez-Arce, P.; Townsend, P. D.; Hole, D. E.

2008-01-01

X-ray diffraction measurements, during halogen lamp illumination to simulate sunlight, (TXRD) show a phase transition from variscite (AlPO 4·H 2O) Messbach to variscite Lucin and a loss of the dark green colour. The differential-thermal and thermo-gravimetric (DTA-TG) analyses and thermoluminescence (TL) peaks all depict this first-order phase transition which takes place under sunlight. From the water vaporization temperature up to circa 650 °C, a second-order phase transition progressively occurs from variscite to berlinite (AlPO 4) by loss of a second unit of water with hydrogen bonded to the lattice. The ion beam luminescence (IBL) spectra of the Zamora variscite display a spectral band from 500 to 570 nm attributed to [UO 2] 2+ in phosphates, and another spectral band from 670 to 740 nm is linked with Cr(VI) 3+ defects situated in octahedral Al(VI) 3+ positions. In the hydrous variscite lattice, the Al-O and P-O chemical bonds are mainly covalent; with the degree of covalency of the P-O chemical bond significantly larger than of Al-O. This open structure of variscite, which has a crystal field of reduced strength, involves small shifts of the absorption bands which intensify the blue-green transmission producing the characteristic emerald colour of the dark green variscite of Zamora. These data provide a valuable basis for detection of solarization damage in historic crafts with inlaid variscite in the Museo del Prado (Madrid, Spain).

Microbial phosphorous mobilization strategies across a natural nutrient limitation gradient

NASA Astrophysics Data System (ADS)

Walker, R.; Wang, S.; Nico, P. S.; Fox, P. M.; Hao, Z.; Karaoz, U.; Torok, T.; Brodie, E.; Chakraborty, R.; Hao, Z.

2016-12-01

Phosphorus (P) is a critical nutrient and frequently limits primary productivity in terrestrial ecosystems. Microorganisms have evolved an array of strategies to mobilize occluded and insoluble P and may be important regulators of P availability to vegetation. Understanding the mechanisms of P mobilization, the breadth of microorganisms responsible, and the impact of these organisms on vegetation growth remains an important knowledge gap for both predicting ecosystem productivity and harnessing microbial functions to improve vegetation growth. To determine the relationship between soil development, phosphorus availability and P mobilizing microorganisms and their strategies we are studying a marine terrace chronosequence (Ecological Staircase, Mendocino County, CA) representing a fertility gradient culminating in P-limited pygmy forests that provide an ideal natural observatory to investigate how plant-microbe interactions co-evolve in response to P stress. Soil mineralogical analysis identified acidic soils bearing iron and aluminum phosphates and phytate as the dominant forms of occluded inorganic and organic P, respectively. Several diverse bacterial and fungal strains were isolated on media with AlPO4, FePO4, or phytate as the sole P source. Most microorganisms were able to utilize AlPO4 as a sole P source, with fewer subsisting on FePO4 or phytate. Terraces with a higher fraction of occluded and organic P harbored the greatest abundance of P-mobilizing microorganisms, with a significant proportion coming from the Burkholderia. Isolates that exhibited significant excess P mobilization were inoculated with Arabidopsis and Switchgrass plants grown with insoluble P forms had a positive impact on growth. These results indicate that rhizosphere microorganisms that have evolved under extreme nutrient limitation have an extended capacity for P solubilization, and could potentially be harnessed to alleviate P stress for plants. The detailed mechanisms for P mobilization by these isolates is under investigation.

A Novel Conductometric Urea Biosensor with Improved Analytical Characteristic Based on Recombinant Urease Adsorbed on Nanoparticle of Silicalite

NASA Astrophysics Data System (ADS)

Velychko, T. P.; Soldatkin, O. O.; Melnyk, V. G.; Marchenko, S. V.; Kirdeciler, S. K.; Akata, B.; Soldatkin, A. P.; El'skaya, A. V.; Dzyadevych, S. V.

2016-02-01

Development of a conductometric biosensor for the urea detection has been reported. It was created using a non-typical method of the recombinant urease immobilization via adsorption on nanoporous particles of silicalite. It should be noted that this biosensor has a number of advantages, such as simple and fast performance, the absence of toxic compounds during biosensor preparation, and high reproducibility (RSD = 5.1 %). The linear range of urea determination by using the biosensor was 0.05-15 mM, and a lower limit of urea detection was 20 μM. The bioselective element was found to be stable for 19 days. The characteristics of recombinant urease-based biomembranes, such as dependence of responses on the protein and ion concentrations, were investigated. It is shown that the developed biosensor can be successfully used for the urea analysis during renal dialysis.

ADSORPTION AND MEMBRANE SEPARATION MEASUREMENTS WITH MIXTURES OF ETHANOL, ACETIC ACID, AND WATER

EPA Science Inventory

Biomass fermentation produces ethanol and other renewable biofuels. Pervaporation using hydrophobic membranes is potentially a cost-effective means of removing biofuels from fermentation broths for small- to medium-scale applications. Silicalite-filled polydimethylsiloxane (PDMS)...

Materials Data on Al(PO3)3 (SG:9) by Materials Project

DOE Data Explorer

Kristin Persson

2014-07-09

Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

Materials Data on Al(PO3)3 (SG:220) by Materials Project

DOE Data Explorer

Kristin Persson

2014-11-02

Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

Materials Data on Al(PO3)3 (SG:165) by Materials Project

DOE Data Explorer

Kristin Persson

2014-07-09

Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

New Sequences with Low Correlation and Large Family Size

NASA Astrophysics Data System (ADS)

Zeng, Fanxin

In direct-sequence code-division multiple-access (DS-CDMA) communication systems and direct-sequence ultra wideband (DS-UWB) radios, sequences with low correlation and large family size are important for reducing multiple access interference (MAI) and accepting more active users, respectively. In this paper, a new collection of families of sequences of length pn-1, which includes three constructions, is proposed. The maximum number of cyclically distinct families without GMW sequences in each construction is φ(pn-1)/n·φ(pm-1)/m, where p is a prime number, n is an even number, and n=2m, and these sequences can be binary or polyphase depending upon choice of the parameter p. In Construction I, there are pn distinct sequences within each family and the new sequences have at most d+2 nontrivial periodic correlation {-pm-1, -1, pm-1, 2pm-1,…,dpm-1}. In Construction II, the new sequences have large family size p2n and possibly take the nontrivial correlation values in {-pm-1, -1, pm-1, 2pm-1,…,(3d-4)pm-1}. In Construction III, the new sequences possess the largest family size p(d-1)n and have at most 2d correlation levels {-pm-1, -1,pm-1, 2pm-1,…,(2d-2)pm-1}. Three constructions are near-optimal with respect to the Welch bound because the values of their Welch-Ratios are moderate, WR_??_d, WR_??_3d-4 and WR_??_2d-2, respectively. Each family in Constructions I, II and III contains a GMW sequence. In addition, Helleseth sequences and Niho sequences are special cases in Constructions I and III, and their restriction conditions to the integers m and n, pm≠2 (mod 3) and n≅0 (mod 4), respectively, are removed in our sequences. Our sequences in Construction III include the sequences with Niho type decimation 3·2m-2, too. Finally, some open questions are pointed out and an example that illustrates the performance of these sequences is given.

Simulating adsorptive expansion of zeolites: application to biomass-derived solutions in contact with silicalite.

PubMed

Santander, Julian E; Tsapatsis, Michael; Auerbach, Scott M

2013-04-16

We have constructed and applied an algorithm to simulate the behavior of zeolite frameworks during liquid adsorption. We applied this approach to compute the adsorption isotherms of furfural-water and hydroxymethyl furfural (HMF)-water mixtures adsorbing in silicalite zeolite at 300 K for comparison with experimental data. We modeled these adsorption processes under two different statistical mechanical ensembles: the grand canonical (V-Nz-μg-T or GC) ensemble keeping volume fixed, and the P-Nz-μg-T (osmotic) ensemble allowing volume to fluctuate. To optimize accuracy and efficiency, we compared pure Monte Carlo (MC) sampling to hybrid MC-molecular dynamics (MD) simulations. For the external furfural-water and HMF-water phases, we assumed the ideal solution approximation and employed a combination of tabulated data and extended ensemble simulations for computing solvation free energies. We found that MC sampling in the V-Nz-μg-T ensemble (i.e., standard GCMC) does a poor job of reproducing both the Henry's law regime and the saturation loadings of these systems. Hybrid MC-MD sampling of the V-Nz-μg-T ensemble, which includes framework vibrations at fixed total volume, provides better results in the Henry's law region, but this approach still does not reproduce experimental saturation loadings. Pure MC sampling of the osmotic ensemble was found to approach experimental saturation loadings more closely, whereas hybrid MC-MD sampling of the osmotic ensemble quantitatively reproduces such loadings because the MC-MD approach naturally allows for locally anisotropic volume changes wherein some pores expand whereas others contract.

Universal elastic-hardening-driven mechanical instability in α-quartz and quartz homeotypes under pressure

PubMed Central

Dong, Juncai; Zhu, Hailiang; Chen, Dongliang

2015-01-01

As a fundamental property of pressure-induced amorphization (PIA) in ice and ice-like materials (notably α-quartz), the occurrence of mechanical instability can be related to violation of Born criteria for elasticity. The most outstanding elastic feature of α-quartz before PIA has been experimentally reported to be the linear softening of shear modulus C44, which was proposed to trigger the transition through Born criteria B3. However, by using density-functional theory, we surprisingly found that both C44 and C66 in α-quartz exhibit strong nonlinearity under compression and the Born criteria B3 vanishes dominated by stiffening of C14, instead of by decreasing of C44. Further studies of archetypal quartz homeotypes (GeO2 and AlPO4) repeatedly reproduced the same elastic-hardening-driven mechanical instability, suggesting a universal feature of this family of crystals and challenging the long-standing idea that negative pressure derivatives of individual elastic moduli can be interpreted as the precursor effect to an intrinsic structural instability preceding PIA. The implications of this elastic anomaly in relation to the dispersive softening of the lowest acoustic branch and the possible transformation mechanism were also discussed. PMID:26099720

Universal elastic-hardening-driven mechanical instability in α-quartz and quartz homeotypes under pressure.

PubMed

Dong, Juncai; Zhu, Hailiang; Chen, Dongliang

2015-06-23

As a fundamental property of pressure-induced amorphization (PIA) in ice and ice-like materials (notably α-quartz), the occurrence of mechanical instability can be related to violation of Born criteria for elasticity. The most outstanding elastic feature of α-quartz before PIA has been experimentally reported to be the linear softening of shear modulus C44, which was proposed to trigger the transition through Born criteria B3. However, by using density-functional theory, we surprisingly found that both C44 and C66 in α-quartz exhibit strong nonlinearity under compression and the Born criteria B3 vanishes dominated by stiffening of C14, instead of by decreasing of C44. Further studies of archetypal quartz homeotypes (GeO2 and AlPO4) repeatedly reproduced the same elastic-hardening-driven mechanical instability, suggesting a universal feature of this family of crystals and challenging the long-standing idea that negative pressure derivatives of individual elastic moduli can be interpreted as the precursor effect to an intrinsic structural instability preceding PIA. The implications of this elastic anomaly in relation to the dispersive softening of the lowest acoustic branch and the possible transformation mechanism were also discussed.

Coinage metal complexes of 2-diphenylphosphino-3-methylindole.

PubMed

Koshevoy, Igor O; Shakirova, Julia R; Melnikov, Alexei S; Haukka, Matti; Tunik, Sergey P; Pakkanen, Tapani A

2011-08-21

Coordination of P,N indolyl-phosphine ligands to Au(I), Ag(I) and Cu(I) metal ions under weakly basic conditions results in easy deprotonation of the indolyl N-H function and effective formation of a family of homo- and heterobimetallic complexes MM'(PPh(2)C(9)H(7)N)(2) (M = M' = Au (2), Ag (5); M = Au, M' = Cu (3), Ag (4)). The latter (4) exists as an inseparable mixture of four different complexes, which are in equilibrium driven by slow dynamics. The reaction of silver(I) and copper(I) ions with PPh(2)(C(9)H(8)N) affords a rare tetranuclear Z-shaped cluster Ag(2)Cu(2)(PPh(2)C(9)H(7)N)(4) (6), which exhibits red luminescence in solid state (650 nm) and a weak dual emission in solution with the main component in the near-IR region (746 nm). This journal is © The Royal Society of Chemistry 2011

Inactivated Enterovirus 71 Vaccine Produced by 200-L Scale Serum-Free Microcarrier Bioreactor System Provides Cross-Protective Efficacy in Human SCARB2 Transgenic Mouse.

PubMed

Wu, Chia-Ying; Lin, Yi-Wen; Kuo, Chia-Ho; Liu, Wan-Hsin; Tai, Hsiu-Fen; Pan, Chien-Hung; Chen, Yung-Tsung; Hsiao, Pei-Wen; Chan, Chi-Hsien; Chang, Ching-Chuan; Liu, Chung-Cheng; Chow, Yen-Hung; Chen, Juine-Ruey

2015-01-01

Epidemics and outbreaks caused by infections of several subgenotypes of EV71 and other serotypes of coxsackie A viruses have raised serious public health concerns in the Asia-Pacific region. These concerns highlight the urgent need to develop a scalable manufacturing platform for producing an effective and sufficient quantity of vaccines against deadly enteroviruses. In this report, we present a platform for the large-scale production of a vaccine based on the inactivated EV71(E59-B4) virus. The viruses were produced in Vero cells in a 200 L bioreactor with serum-free medium, and the viral titer reached 10(7) TCID50/mL 10 days after infection when using an MOI of 10(-4). The EV71 virus particles were harvested and purified by sucrose density gradient centrifugation. Fractions containing viral particles were pooled based on ELISA and SDS-PAGE. TEM was used to characterize the morphologies of the viral particles. To evaluate the cross-protective efficacy of the EV71 vaccine, the pooled antigens were combined with squalene-based adjuvant (AddaVAX) or aluminum phosphate (AlPO4) and tested in human SCARB2 transgenic (Tg) mice. The Tg mice immunized with either the AddaVAX- or AlPO4-adjuvanted EV71 vaccine were fully protected from challenges by the subgenotype C2 and C4 viruses, and surviving animals did not show any degree of neurological paralysis symptoms or muscle damage. Vaccine treatments significantly reduced virus antigen presented in the central nervous system of Tg mice and alleviated the virus-associated inflammatory response. These results strongly suggest that this preparation results in an efficacious vaccine and that the microcarrier/bioreactor platform offers a superior alternative to the previously described roller-bottle system.

A Controlled Family Study of Children with DSM-IV Bipolar-I Disorder and Psychiatric Comorbidity

PubMed Central

Wozniak, Janet; Faraone, Stephen V.; Mick, Eric; Monuteaux, Michael; Coville, Allison; Biederman, Joseph

2011-01-01

Objective To estimate the spectrum of familial risk for psychopathology in first degree relatives of children with unabridged DSM-IV Bipolar-I Disorder (BP-I). Methods We conducted a blinded, controlled family study using structured diagnostic interviews of 157 children with BP-I probands (N=487 1st degree relatives), 162 ADHD (without BP-I) probands (N=511 1st degree relatives), and 136 healthy control (without ADHD or BP-I) probands (N=411 1st degree relatives). Results The morbid risk (MR) of BP-I disorder in relatives of BP-I probands (MR=0.18) was increased 4-fold (95%CI=2.3-6.9, p<0.001) over the risk to relatives of control probands (MR=0.05) and 3.5-fold (95%CI=2.1-5.8, p<0.001) over the risk to relatives of ADHD probands (MR=0.06). In addition, relatives of children with BP-I disorder had high rates of psychosis, major depression, multiple anxiety disorders, substance use disorders, ADHD, and antisocial disorders compared with relatives of Control probands. Only the effect for antisocial disorders lost significance after accounted for by the corresponding diagnosis in the proband. Familial rates of ADHD did not differ between ADHD and BP-I probands. Conclusions Our results document an increased familial risk for BP-I disorder in relatives of pediatric probands with DSM-IV BP-I disorder. Relatives of probands with BP-I disorder were also at increased risk for other psychiatric disorders frequently associated with pediatric BP-I disorder. These results support the validity of the diagnosis of BP-I in children as defined by DSM-IV. More work is needed to better understand the nature of the association between these disorders in probands and relatives. PMID:19891803

Familial Kleine-Levin Syndrome: A Specific Entity?

PubMed Central

Nguyen, Quang Tuan Remy; Groos, Elisabeth; Leclair-Visonneau, Laurène; Monaca-Charley, Christelle; Rico, Tom; Farber, Neal; Mignot, Emmanuel; Arnulf, Isabelle

2016-01-01

Study Objectives: Kleine-Levin syndrome (KLS) is a rare, mostly sporadic disorder, characterized by intermittent episodes of hypersomnia plus cognitive and behavior disorders. Although its cause is unknown, multiplex families have been described. We contrasted the clinical and biological features of familial versus sporadic KLS. Methods: Two samples of patients with KLS from the United States and France (n = 260) were studied using clinical interviews and human leukocyte antigen (HLA) genotyping. A multiplex family contained two or more first- or second-degree affected relatives (familial cases). Results: Twenty-one patients from 10 multiplex families (siblings: n = 12, including two pairs of monozygotic twins; parent-child: n = 4; cousins: n = 2; uncle-nephews: n = 3) and 239 patients with sporadic KLS were identified, yielding to 4% multiplex families and 8% familial cases. The simplex and multiplex families did not differ for autoimmune, neurological, and psychiatric disorders. Age, sex ratio, ethnicity, HLA typing, karyotyping, disease course, frequency, and duration of KLS episodes did not differ between groups. Episodes were less frequent in familial versus sporadic KLS (2.3 ± 1.8/y versus 3.8 ± 3.7/y, P = 0.004). Menses triggered more frequently KLS onset in the nine girls with familial KLS (relative risk, RR = 4.12, P = 0.03), but not subsequent episodes. Familial cases had less disinhibited speech (RR = 3.44, P = 0.049), less combined hypophagia/hyperphagia (RR = 4.38, P = 0.006), more abrupt termination of episodes (RR = 1.45, P = 0.04) and less postepisode insomnia (RR = 2.16, P = 0.008). There was similar HLA DQB1 distribution in familial versus sporadic cases and no abnormal karyotypes. Conclusion: Familial KLS is mostly present in the same generation, and is clinically similar to but slightly less severe than sporadic KLS. Citation: Nguyen QT, Groos E, Leclair-Visonneau L, Monaca-Charley C, Rico T, Farber N, Mignot E, Arnulf I. Familial Kleine-Levin syndrome: a specific entity? SLEEP 2016;39(8):1535–1542. PMID:27253765

Reference spectra of important adsorbed organic and inorganic phosphate binding forms for soil P speciation using synchrotron-based K-edge XANES spectroscopy.

PubMed

Prietzel, Jörg; Harrington, Gertraud; Häusler, Werner; Heister, Katja; Werner, Florian; Klysubun, Wantana

2016-03-01

Direct speciation of soil phosphorus (P) by linear combination fitting (LCF) of P K-edge XANES spectra requires a standard set of spectra representing all major P species supposed to be present in the investigated soil. Here, available spectra of free- and cation-bound inositol hexakisphosphate (IHP), representing organic P, and of Fe, Al and Ca phosphate minerals are supplemented with spectra of adsorbed P binding forms. First, various soil constituents assumed to be potentially relevant for P sorption were compared with respect to their retention efficiency for orthophosphate and IHP at P levels typical for soils. Then, P K-edge XANES spectra for orthophosphate and IHP retained by the most relevant constituents were acquired. The spectra were compared with each other as well as with spectra of Ca, Al or Fe orthophosphate and IHP precipitates. Orthophosphate and IHP were retained particularly efficiently by ferrihydrite, boehmite, Al-saturated montmorillonite and Al-saturated soil organic matter (SOM), but far less efficiently by hematite, Ca-saturated montmorillonite and Ca-saturated SOM. P retention by dolomite was negligible. Calcite retained a large portion of the applied IHP, but no orthophosphate. The respective P K-edge XANES spectra of orthophosphate and IHP adsorbed to ferrihydrite, boehmite, Al-saturated montmorillonite and Al-saturated SOM differ from each other. They also are different from the spectra of amorphous FePO4, amorphous or crystalline AlPO4, Ca phosphates and free IHP. Inclusion of reference spectra of orthophosphate as well as IHP adsorbed to P-retaining soil minerals in addition to spectra of free or cation-bound IHP, AlPO4, FePO4 and Ca phosphate minerals in linear combination fitting exercises results in improved fit quality and a more realistic soil P speciation. A standard set of P K-edge XANES spectra of the most relevant adsorbed P binding forms in soils is presented.

ALPO Observations of Saturn During the 2005-2006 Apparition

NASA Astrophysics Data System (ADS)

Benton, Julius L., Jr.

2008-12-01

For the 2005-2006 apparition (from August 23, 2005 through June 12, 2006) the ALPO Saturn Section received 414 visual observations and digital images submitted by 50 observers in the USA, Germany, Romania, Japan, France, Canada, Philippines, Italy, UK, Spain, and The Netherlands. Apertures used to perform observations ranged from 12.5cm up to 76.2cm. Saturn observers occasionally reported discrete, short-lived dark features in the South Equatorial Belt during the observing season, as well as small enduring white spots in the South Polar Region (SPR), the South Equatorial Belt Zone (SEBZ) and South Tropical Zone (STrZ). The SEBZ and STrZ white spots, first detected in November and December 2005, exhibited notable changes in morphology as the apparition progressed. A few recurring central meridian transit timings were submitted for some of these features. The inclination of Saturn's ring system towards Earth attained a maximum value of -20.21° on April 4, 2006, so observers could view and image considerable portions of Saturn's Southern Hemisphere and South face of the rings throughout the observing season. With the diminishing ring tilt, regions of the Northern Hemisphere, such as the North Polar Cap and North Polar Region were becoming accessible to our Earth-based telescope. A summary of visual observations and digital images of Saturn contributed during the apparition are discussed, including the results of continuing efforts to image the bicolored aspect and azimuthal brightness asymmetries of the rings. Accompanying the report are references, drawings, photographs, digital images, graphs, and tables.

ATLAS Mission Planner’s Guide for the ATLAS Launch Vehicle Family. Revision 3

DTIC Science & Technology

1992-04-01

000 oIgo lat -. o 0 14o, 0 1 a Eta IU -~a..---.. c - 6j0 t 4 - 1 I 4 IILI - K- 0 ’fiuue 8-. 1 i peaf imivjiom activvem at wacecimat sqwtiom. 0b1...unwt supcnede #.he Mis~fm Pbnnr’s Gudec &W th&e Aas Launch Whak Family - Revison 2.w JOiY 1990 Appnwed by: Deonaia R. Ikuiha Bn) Vk~Ptcsidcnt % 1 "Pce...ac totio n A r i wo v al 21 March 1999 1 10 July 90 2 April 1992 3- 1 *Section 2 is a complete update of Vehicle performanceI Secion 3 mujor updates

La calotta polare sud di Mars

NASA Astrophysics Data System (ADS)

di Giovanni, Giovanni

2006-06-01

The paper discusses the variations in the ice-retreat rate of the south polar cap of Mars in springtime during the 2003 and 2005 apparitions. For this we have measured the planetocentric cap amplitude on images of the Mars Sections of the Italian Union of Amateur Astronomers (UAI), the American Association of Lunar and Planetary Observers (ALPO) and ALPO Japan in the relevant Internet sites. A reasonable first approach to the problem was to perform a simple heat-balance model of Mars' ice cap including solar insolation, surface thermal emission, condensation and sublimation of carbon dioxide frost. The model doesn't include several important physical conditions, such as atmospherical absorption of radiation etc. and other components of ice (i.e. dust, H2O etc.). A suitable mathematical continue function θ(Ls) concerning the planetocentric amplitude of the cap as a function of the areocentric solar longitude on Mars (Ls) has been used to fit the experimental points in a classical diagram cap amplitude versus Ls. The correlation coefficient resulted 0.95. The second derivative of the function (d2θ/dLs2) suggests the existence of three important points during the spring recession: a) at Ls≍228° the highest sublimation rate is observe; b) at Ls≍245° (near perihelion) the highest retraction speed of the edge cap occurs, when the solar radiation flux over the south pole exceeds the flux over the equatorial zone; c) at Ls>285° the retraction speed of the cap's edge is constant. With the same function θ(Ls) we have worked out the ice thickness for every degrees in Ls, sublimation diurnal rate and total mass of seasonal cap. The ring of ice around to the pole, whose existence was suggested by Cross, was not revealed.

Zeolite Crystal Growth (ZCG) Flight on USML-2

NASA Technical Reports Server (NTRS)

Sacco, Albert, Jr.; Bac, Nurcan; Warzywoda, Juliusz; Guray, Ipek; Marceau, Michelle; Sacco, Teran L.; Whalen, Leah M.

1997-01-01

The extensive use of zeolites and their impact on the world's economy has resulted in many efforts to characterize their structure, and improve the knowledge base for nucleation and growth of these crystals. The zeolite crystal growth (ZCG) experiment on USML-2 aimed to enhance the understanding of nucleation and growth of zeolite crystals, while attempting to provide a means of controlling the defect concentration in microgravity. Zeolites A, X, Beta, and Silicalite were grown during the 16 day - USML-2 mission. The solutions where the nucleation event was controlled yielded larger and more uniform crystals of better morphology and purity than their terrestrial/control counterparts. The external surfaces of zeolite A, X, and Silicalite crystals grown in microgravity were smoother (lower surface roughness) than their terrestrial controls. Catalytic studies with zeolite Beta indicate that crystals grown in space exhibit a lower number of Lewis acid sites located in micropores. This suggests fewer structural defects for crystals grown in microgravity. Transmission electron micrographs (TEM) of zeolite Beta crystals also show that crystals grown in microgravity were free of line defects while terrestrial/controls had substantial defects.

Matrimonial and Family Proceedings (Northern Ireland) Order, 1989 (S.I. No. 677 of 1989 [N.I. 4]).

PubMed

1989-01-01

This Northern Ireland Order 1) replaces the present restriction on the presentation of a petition for divorce within 3 years of marriage without the leave of the court with an absolute bar on the presentation of a petition within 2 years of marriage; 2) provides for the extension of the 3-year period within which certain petitions for a decree of nullity must be presented in cases where the petitioner suffers from mental disorder; 3) amends the Matrimonial Causes (Northern Ireland) Order 1978 (N.I. 15) and the Domestic Proceedings (Northern Ireland) Order 1980 (N.I. 5) in relation to the powers of courts to provide for financial relief in matrimonial and certain other family proceedings; 4) confers new powers on the High Court to grant financial relief to a party to a marriage following a divorce, annulment, or legal separation granted in an overseas country which is recognized as valid in Northern Ireland; 5) makes fresh provision as to the powers of courts to make declarations relating to the status of a person; 6) abolishes the right to petition for jactitation of marriage; and 7) reenacts with amendments Sched. 2 to the Rent (Northern Ireland) Order 1978 (N.I. 20).

Workshop on Future Directions for Optical Information Processing.

DTIC Science & Technology

1981-03-01

h . The i reference point source simultaneously illuminates the i member of a family of n phase-encoding Aiffusers (e.g. shower glass , ground glass ...diffuser (ground glass ) section illuminated with a plane wave [35.37). The n(n-1) - 4(3) - 12 crosstalk terms have been distributed into the noise...for 2x2 input Fig. 6. Outnut of processor analogous to that array, l.Sx magnifier, ground glass diffuser of Fig. 5, but using spherical wavefront and

Annual Research Progress Report, Fiscal Year 1983,

DTIC Science & Technology

1983-10-01

Liver Plasma Membranes. Acceoted by Endocrinology, Sep 83. Submitted for Publication: Friedl, K.E. and Plymate, S.R.: Effects of Obesity on...i4c)ttle Feed and the Effect of Lactat ion i-i :’ost 0-tarti1u Wei-ght 1 ,oss. Presente.i to 10t h Anniversary Family Pract ico \\Iumni C’onterence...Madiga n Army Med icai C’enter, Tacorma, WA, Jan 1 . DEPARTME.N1 ()F MEDICINE Fincher, M.E., Little, J.S., PLymate, H.R. and Fariss, H.L.: Effect of

Crystallographic isomorphism in the structural type of α-HgI{sub 2} by example of KHgI{sub 3} · H{sub 2}O, β-Ag{sub 2}HgI{sub 4}, and β-Cu{sub 2}HgI{sub 4}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borisov, S. V., E-mail: borisov@niic.nsc.ru; Magarill, S. A.; Pervukhina, N. V.

The structure of KHgI{sub 3} · H{sub 2}O is assigned to the family of crystal structures having the three-layer cubic packing of iodine anions with cations in the tetrahedral voids (the structures of α-HgI{sub 2}, β-Ag{sub 2}HgI{sub 4}, and β-Cu{sub 2}HgI{sub 4} among them). Crystallographic analysis shows that the nodes of the three-layer close packing are populated by iodine anions and K cations in the ratio 3/4: 1/4. Transformation of the structure of α-HgI{sub 2} into the structure of KHgI{sub 3} · H{sub 2}O can be formally represented as the replacement of (HgI){sub n}{sup +} fragments by (KH{sub 2}O){sub n}{supmore » +} fragments: (Hg{sub 2}I{sub 4})–(HgI){sup +} + (KH{sub 2}O){sub n}{sup +} = KHgI{sub 3} · H{sub 2}O. Perforated layers of vertex-sharing HgI{sub 4} tetrahedra break down into parallel isolated chains. Channels formed in place of I–Hg–I–Hg–fragments are occupied by–H{sub 2}O–K–-H{sub 2}-O-K-H{sub 2}O-chains weakly bound to neighbors.« less

The Effect of a Stimulating Learning Environment on Pre-Service Teachers' Motivation and 21st Century Skills

ERIC Educational Resources Information Center

Nissim, Yonit; Weissblueth, Eyal; Scott-Webber, Lennie; Amar, Shimon

2016-01-01

We investigated the effect of an innovative technology-supported learning environment on pre-service student teachers' motivation and 21st century skills. Students and instructors filled-in the Active Learning Post Occupancy Evaluation (AL-POE) questionnaire. Analysis included tests for individual items and a comparison of the overall mean,…

Biosynthesis of amorphous mesoporous aluminophosphates using yeast cells as templates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sifontes, Ángela B., E-mail: asifonte@ivic.gob.ve; González, Gema; Tovar, Leidy M.

2013-02-15

Graphical abstract: Display Omitted Highlights: ► Amorphous aluminophosphates can take place using yeast as template. ► A mesoporous material was obtained. ► The specific surface area after calcinations ranged between 176 and 214 m{sup 2} g{sup −1}. -- Abstract: In this study aluminophosphates have been synthesized from aluminum isopropoxide and phosphoric acid solutions using yeast cells as template. The physicochemical characterization was carried out by thermogravimetric analysis; X-ray diffraction; Fourier transform infrared; N{sub 2} adsorption–desorption isotherms; scanning electron microscopy; transmission electron microscopy and potentiometric titration with N-butylamine for determination of: thermal stability; crystalline structure; textural properties; morphology and surface acidity,more » respectively. The calcined powders consisted of an intimate mixture of amorphous and crystallized AlPO particles with sizes between 23 and 30 nm. The average pore size observed is 13–16 nm and the specific surface area after calcinations (at 650 °C) ranged between 176 and 214 m{sup 2} g{sup −1}.« less

Influence of Process Parameters on Laser Weld Characteristics in Aluminum Alloys

DTIC Science & Technology

1988-08-01

sacrifices that my family has so patiently endured through these long years of my education . I. .i % 1IM Chapter 1 INTRODUCTION Multi-kilowatt CO 2 lasers...ep taxil gowt frmp rn eal lqa inad g lm rto of pase n HA (x 00) I -. _k .... 4 122 In the HAZ close to the fusion boundary, there is evidence of

Poisson's Ratio and Auxetic Properties of Natural Rocks

NASA Astrophysics Data System (ADS)

Ji, Shaocheng; Li, Le; Motra, Hem Bahadur; Wuttke, Frank; Sun, Shengsi; Michibayashi, Katsuyoshi; Salisbury, Matthew H.

2018-02-01

Here we provide an appraisal of the Poisson's ratios (υ) for natural elements, common oxides, silicate minerals, and rocks with the purpose of searching for naturally auxetic materials. The Poisson's ratios of equivalently isotropic polycrystalline aggregates were calculated from dynamically measured elastic properties. Alpha-cristobalite is currently the only known naturally occurring mineral that has exclusively negative υ values at 20-1,500°C. Quartz and potentially berlinite (AlPO4) display auxetic behavior in the vicinity of their α-β structure transition. None of the crystalline igneous and metamorphic rocks (e.g., amphibolite, gabbro, granite, peridotite, and schist) display auxetic behavior at pressures of >5 MPa and room temperature. Our experimental measurements showed that quartz-rich sedimentary rocks (i.e., sandstone and siltstone) are most likely to be the only rocks with negative Poisson's ratios at low confining pressures (≤200 MPa) because their main constituent mineral, α-quartz, already has extremely low Poisson's ratio (υ = 0.08) and they contain microcracks, micropores, and secondary minerals. This finding may provide a new explanation for formation of dome-and-basin structures in quartz-rich sedimentary rocks in response to a horizontal compressional stress in the upper crust.

Resolution enhancement using a new multiple-pulse decoupling sequence for quadrupolar nuclei.

PubMed

Delevoye, L; Trébosc, J; Gan, Z; Montagne, L; Amoureux, J-P

2007-05-01

A new decoupling composite pulse sequence is proposed to remove the broadening on spin S=1/2 magic-angle spinning (MAS) spectra arising from the scalar coupling with a quadrupolar nucleus I. It is illustrated on the (31)P spectrum of an aluminophosphate, AlPO(4)-14, which is broadened by the presence of (27)Al/(31)P scalar couplings. The multiple-pulse (MP) sequence has the advantage over the continuous wave (CW) irradiation to efficiently annul the scalar dephasing without reintroducing the dipolar interaction. The MP decoupling sequence is first described in a rotor-synchronised version (RS-MP) where one parameter only needs to be adjusted. It clearly avoids the dipolar recoupling in order to achieve a better resolution than using the CW sequence. In a second improved version, the MP sequence is experimentally studied in the vicinity of the perfect rotor-synchronised conditions. The linewidth at half maximum (FWHM) of 65 Hz using (27)Al CW decoupling decreases to 48 Hz with RS-MP decoupling and to 30 Hz with rotor-asynchronised MP (RA-MP) decoupling. The main phenomena are explained using both experimental results and numerical simulations.

The predominance of Ethiopian specific Mycobacterium tuberculosis families and minimal contribution of Mycobacterium bovis in tuberculous lymphadenitis patients in Southwest Ethiopia.

PubMed

Tadesse, Mulualem; Abebe, Gemeda; Bekele, Alemayehu; Bezabih, Mesele; de Rijk, Pim; Meehan, Conor J; de Jong, Bouke C; Rigouts, Leen

2017-11-01

Ethiopia has an extremely high rate of extrapulmonary tuberculosis, dominated by tuberculous lymphadenitis (TBLN). However, little is known about Mycobacterium tuberculosis complex (MTBc) lineages responsible for TBLN in Southwest Ethiopia. A total of 304 MTBc isolates from TBLN patients in Southwest Ethiopia were genotyped primarily by spoligotyping. Isolates of selected spoligotypes were further analyzed by 15-loci mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) (n=167) and qPCR-based single nucleotide polymorphism (n=38). Isolates were classified into main phylogenetic lineages and families by using the reference strain collections and identification tools available at MIRU-VNTRplus data base. Resistance to rifampicin was determined by Xpert MTB/RIF. The majority of isolates (248; 81.6%) belonged to the Euro-American lineage (Lineage 4), with the ill-defined T and Haarlem as largest families comprising 116 (38.2%) and 43 (14.1%) isolates respectively. Of the T family, 108 isolates were classified as being part of the newly described Ethiopian families, namely Ethiopia_2 (n=44), Ethiopia_3 (n=34) and Ethiopia_H 37 Rv-like (n=30). Other sub-lineages included URAL (n=18), S (n=17), Uganda I (n=16), LAM (n=13), X (n=5), TUR (n=5), Uganda II (n=4) and unknown (n=19). Lineage 3 (Delhi/CAS) was the second most common lineage comprising 44 (14.5%) isolates. Interestingly, six isolates (2%) were belonged to Lineage 7, unique to Ethiopia. Lineage 1 (East-African Indian) and Lineage 2 (Beijing) were represented by 3 and 1 isolates respectively. M. bovis was identified in only two (0.7%) TBLN cases. The cluster rate was highest for Ethiopia_3 isolates showing clonal similarity with isolates from North Ethiopia. Lineage 3 was significantly associated with rifampicin resistance. In TBLN in Southwest Ethiopia, the recently described Ethiopia specific Lineage 4 families were predominant, followed by Lineage 3 and Lineage 4-Haarlem. The contribution of M. bovis in TBLN infection is minimal. Copyright © 2017. Published by Elsevier B.V.

The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives.

PubMed

Taslimi, Parham; Gulcin, Ilhami; Ozgeris, Bunyamin; Goksu, Suleyman; Tumer, Ferhan; Alwasel, Saleh H; Supuran, Claudiu T

2016-01-01

Carbonic anhydrases (CAs, EC 4.2.1.1) had six genetically distinct families described to date in various organisms. There are 16 known CA isoforms in humans. Human CA isoenzymes I and II (hCA I and hCA II) are ubiquitous cytosolic isoforms. Acetylcholine esterase (AChE. EC 3.1.1.7) is a hydrolase that hydrolyzes the neurotransmitter acetylcholine relaying the signal from the nerve. In this study, some trimethoxyindane derivatives were investigated as inhibitors against the cytosolic hCA I and II isoenzymes, and AChE enzyme. Both hCA isozymes were inhibited by trimethoxyindane derivatives in the low nanomolar range. These compounds were good hCA I inhibitors (Kis in the range of 1.66-4.14 nM) and hCA II inhibitors (Kis of 1.37-3.12 nM) and perfect AChE inhibitors (Kis in the range of 1.87-7.53 nM) compared to acetazolamide as CA inhibitor (Ki: 6.76 nM for hCA I and Ki: 5.85 nM for hCA II) and Tacrine as AChE inhibitor (Ki: 7.64 nM).

SHOX duplications found in some cases with type I Mayer-Rokitansky-Kuster-Hauser syndrome.

PubMed

Gervasini, Cristina; Grati, Francesca Romana; Lalatta, Faustina; Tabano, Silvia; Gentilin, Barbara; Colapietro, Patrizia; De Toffol, Simona; Frontino, Giada; Motta, Francesca; Maitz, Silvia; Bernardini, Laura; Dallapiccola, Bruno; Fedele, Luigi; Larizza, Lidia; Miozzo, Monica

2010-10-01

The Mayer-Rokitansky-Küster-Hauser syndrome is defined as congenital aplasia of müllerian ducts derived structures in females with a normal female chromosomal and gonadal sex. Most cases with Mayer-Rokitansky-Küster-Hauser syndrome are sporadic, although familial cases have been reported. The genetic basis of Mayer-Rokitansky-Küster-Hauser syndrome is largely unknown and seems heterogeneous, and a small number of cases were found to have mutations in the WNT4 gene. The aim of this study was to identify possible recurrent submicroscopic imbalances in a cohort of familial and sporadic cases with Mayer-Rokitansky-Küster-Hauser syndrome. Multiplex ligation-dependent probe amplification was used to screen the subtelomeric sequences of all chromosomes in 30 patients with Mayer-Rokitansky-Küster-Hauser syndrome (sporadic, n = 27 and familial, n = 3). Segregation analysis and pyrosequencing were applied to validate the MLPA results in the informative family. Partial duplication of the Xpter pseudoautosomal region 1 containing the short stature homeobox (SHOX) gene was detected in five patients with Mayer-Rokitansky-Küster-Hauser syndrome (familial, n = 3 and sporadic, n = 2) and not in 53 healthy controls. The duplications were not overlapping, and SHOX was never entirely duplicated. Haplotyping in the informative family revealed that SHOX gene duplication was inherited from the unaffected father and was absent in two healthy sisters. Partial duplication of SHOX gene is found in some cases with both familial and sporadic Mayer-Rokitansky-Küster-Hauser type I syndrome.

Protein classification based on text document classification techniques.

PubMed

Cheng, Betty Yee Man; Carbonell, Jaime G; Klein-Seetharaman, Judith

2005-03-01

The need for accurate, automated protein classification methods continues to increase as advances in biotechnology uncover new proteins. G-protein coupled receptors (GPCRs) are a particularly difficult superfamily of proteins to classify due to extreme diversity among its members. Previous comparisons of BLAST, k-nearest neighbor (k-NN), hidden markov model (HMM) and support vector machine (SVM) using alignment-based features have suggested that classifiers at the complexity of SVM are needed to attain high accuracy. Here, analogous to document classification, we applied Decision Tree and Naive Bayes classifiers with chi-square feature selection on counts of n-grams (i.e. short peptide sequences of length n) to this classification task. Using the GPCR dataset and evaluation protocol from the previous study, the Naive Bayes classifier attained an accuracy of 93.0 and 92.4% in level I and level II subfamily classification respectively, while SVM has a reported accuracy of 88.4 and 86.3%. This is a 39.7 and 44.5% reduction in residual error for level I and level II subfamily classification, respectively. The Decision Tree, while inferior to SVM, outperforms HMM in both level I and level II subfamily classification. For those GPCR families whose profiles are stored in the Protein FAMilies database of alignments and HMMs (PFAM), our method performs comparably to a search against those profiles. Finally, our method can be generalized to other protein families by applying it to the superfamily of nuclear receptors with 94.5, 97.8 and 93.6% accuracy in family, level I and level II subfamily classification respectively. Copyright 2005 Wiley-Liss, Inc.

A new family of N dimensional superintegrable double singular oscillators and quadratic algebra Q(3) ⨁ so(n) ⨁ so(N-n)

NASA Astrophysics Data System (ADS)

Fazlul Hoque, Md; Marquette, Ian; Zhang, Yao-Zhong

2015-11-01

We introduce a new family of N dimensional quantum superintegrable models consisting of double singular oscillators of type (n, N-n). The special cases (2,2) and (4,4) have previously been identified as the duals of 3- and 5-dimensional deformed Kepler-Coulomb systems with u(1) and su(2) monopoles, respectively. The models are multiseparable and their wave functions are obtained in (n, N-n) double-hyperspherical coordinates. We obtain the integrals of motion and construct the finitely generated polynomial algebra that is the direct sum of a quadratic algebra Q(3) involving three generators, so(n), so(N-n) (i.e. Q(3) ⨁ so(n) ⨁ so(N-n)). The structure constants of the quadratic algebra itself involve the Casimir operators of the two Lie algebras so(n) and so(N-n). Moreover, we obtain the finite dimensional unitary representations (unirreps) of the quadratic algebra and present an algebraic derivation of the degenerate energy spectrum of the superintegrable model.

Similar Familial Underpinnings for Full and Subsyndromal Pediatric Bipolar Disorder: A Familial Risk Analysis

PubMed Central

Wozniak, Janet; Uchida, Mai; Faraone, Stephen V.; Fitzgerald, Maura; Vaudreuil, Carrie; Carrellas, Nicholas; Davis, Jacqueline; Wolenski, Rebecca; Biederman, Joseph

2017-01-01

Objectives To examine the validity of subthreshold pediatric bipolar-I (BP-I) disorder, we compared the familial risk for BP-I disorder in child probands with full BP-I disorder, subthreshold BP-I disorder, ADHD, and non-ADHD/non-bipolar disorder controls. Methods Probands were youth ages 6–17 meeting criteria for BP-I disorder, full (N=239) or subthreshold (N=43), and their first degree relatives (N=687 and N=120, respectively). Comparators were youth with ADHD (N=162), controls (N=136), and their first-degree relatives (N=511 and N=411, respectively). We randomly selected 162 non-bipolar ADHD probands and 136 non-bipolar non-ADHD control probands of similar age and sex distribution to the BP-I probands from our case-control ADHD family studies. Psychiatric assessments were made by trained psychometricians using the KSADS-E and SCID structured diagnostic interviews. We analyzed rates of bipolar disorder using multinomial logistic regression. Results Rates of full bipolar-I disorder significantly differed between the four groups (χ23 = 32.72, p<0.001): relatives of full BP-I and relatives of subthreshold BP-I probands had significantly higher rates of full BP-I disorder than relatives of ADHD probands and relatives of control probands. Relatives of full BP-I, subthreshold BP-I, and ADHD probands also had significantly higher rates of major depressive disorder (MDD) compared to relatives of control probands. Conclusions Our results showed that youth with subthreshold BP-I disorder had similarly elevated risk for BP-I disorder and MDD in first-degree relatives as youth with full BP-I disorder. These findings support the diagnostic continuity between subsyndromal and fully syndromatic states of pediatric BP-I disorder. PMID:28544732

Family Housing Self-Help Program: Evaluation and Recommendations for Improvements.

DTIC Science & Technology

1986-07-01

the Army Housing Management Division, Facilities Branch, Office of the Chief of Engineers (OCE), under reimbursable Work Unit QH5, " Family Housing Self...40-A171 466 FAMILY HOUSIN G SB -HEL PROGRAM: KVJ A I N 1/1 u NLASSIFIED L 86 CEI I -T-8 6 /901 IL H I LAl 51 , L 40-N1 L6 132 2= 1.25 LA.11...Laboratory July 1986 Family Housing Self-Help Evaluation and Improvement AD-A171 466 Family Housing Self-Help Program: Evaluation and Recommendations for

Thermodynamics of water intrusion in nanoporous hydrophobic solids.

PubMed

Cailliez, Fabien; Trzpit, Mickael; Soulard, Michel; Demachy, Isabelle; Boutin, Anne; Patarin, Joël; Fuchs, Alain H

2008-08-28

We report a joint experimental and molecular simulation study of water intrusion in silicalite-1 and ferrerite zeolites. The main conclusion of this study is that water condensation takes place through a genuine first-order phase transition, provided that the interconnected pores structure is 3-dimensional. In the extreme confinement situation (ferrierite zeolite), condensation takes place through a continuous transition, which is explained by a shift of both the first-order transition line and the critical point with increasing confinement. The present findings are at odds with the common belief that conventional phase transitions cannot take place in microporous solids such as zeolites. The most important features of the intrusion/extrusion process can be understood in terms of equilibrium thermodynamics considerations. We believe that these findings are very general for hydrophobic solids, i.e. for both nonwetting as well as wetting water-solid interface systems.

Design and Development of Mixed-Metal Oxide Photocatalysts: the Band Engineering Approach

NASA Astrophysics Data System (ADS)

Boltersdorf, Jonathan Andrew

The design and development of mixed-metal oxides incorporating Ag(I), Pb(II), Sn(II), and Bi(III), i.e., with filled d10 or d10s2 electron configurations, have yielded new approaches to tune optical and photocatalytic properties for solar energy conversion. My research efforts in the area of solid-state photochemistry have focused on utilizing flux-mediated ion-exchange methods in conjunction with the band engineering approach to synthesize new materials for solar energy driven total water splitting. Layered perovskite phases and the polysomatic family of tantalate/niobate structures, with the general formula Am+ ( n+1)/mB(3 n+1)O(8n +3) (A = Na, Ag; B = Ta, Nb), have received increasing attention owing to their synthetic flexibility, tunable optical band gaps, and photocatalytic activities for total water splitting. Structures in the family of A m+ (n+1)/ mB(3n +1)O(8n+3) structures are based on the stacking of pentagonal bipyramidal layers, where n defines the average thickness (1 ≤ n ≤ 2) of the BO7 layers that alternate with isolated BO6 octahedra surrounded by A-site cations. Synthetic limitations in the discovery of new phases within the layered perovskites and the Am + (n+1)/mB(3 n+1)O(8n +3) structural families can be addressed with the aid of a metal-salt solvent, known as the molten-salt flux method. The flux synthetic route requires the use of an inorganic salt heated above its melting temperature in order to serve as a solvent system for crystallization. Molten fluxes allow for synthetic modification of particle characteristics and can enable the low temperature stabilization of new compositions and phases with limited stability using ion-exchange reactions (e.g., PbTa4O11, AgLaNb 2O7). Solid-state and flux-mediated exchange methods were utilized in order to synthetically explore and investigate the layered perovskites ALaNb2O7, AA2Nb3O 10, A'2La2Ti3O10 (A' = Rb, Ag; A = Ca, Sr), the Am+ (n+1)/mB 3n+1O(8 n+3) structural family (Am + = Na(I), Ag(I), Pb(II), Sn(II), Bi(III); B = Ta, Nb), Pb3Ta 4O13, PbTa2O6, Bi7Ta 3O18, and Sn2TiO4. The impact of the dimensionality of the structural features on the photocatalytic activities of the metal-oxides will be examined. A comparison of the influence of Ag(I), Pb(II), Sn(II), and Bi(III) cations in combination with Ti(IV), Nb(V), and Ta(V) cations on the optical properties and photocatalytic rates of the mixed-metal oxides will be presented. The results of these investigations have led to new insights into synthetic strategies for the development of new metal-oxide photocatalysts, which have aided in understanding the effects of transition and post-transition metals, structural features, and flux-mediated synthesis methods on the optical and photocatalytic properties of metal oxides for solar fuel production.

Nano-phase separation and structural ordering in silica-rich mixed network former glasses.

PubMed

Liu, Hao; Youngman, Randall E; Kapoor, Saurabh; Jensen, Lars R; Smedskjaer, Morten M; Yue, Yuanzheng

2018-06-13

We investigate the structure, phase separation, glass transition, and crystallization in a mixed network former glass series, i.e., B2O3-Al2O3-SiO2-P2O5 glasses with varying SiO2/B2O3 molar ratio. All the studied glasses exhibit two separate glassy phases: droplet phase (G1) with the size of 50-100 nm and matrix phase (G2), corresponding to a lower calorimetric glass transition temperature (Tg1) and a higher one (Tg2), respectively. Both Tg values decrease linearly with the substitution of B2O3 for SiO2, but the magnitude of the decrease is larger for Tg1. Based on nuclear magnetic resonance and Raman spectroscopy results, we infer that the G1 phase is rich in boroxol rings, while the G2 phase mainly involves the B-O-Si network. Both phases contain BPO4- and AlPO4-like units. Ordered domains occur in G2 upon isothermal and dynamic heating, driven by the structural heterogeneity in the as-prepared glasses. The structural ordering lowers the activation energy of crystal growth, thus promoting partial crystallization of G2. These findings are useful for understanding glass formation and phase separation in mixed network former oxide systems, and for tailoring their properties.

The profile and familiality of personality traits in mood disorder families.

PubMed

Wu, Pei-Jung; Chang, Sheng-Mao; Lu, Ming-Kun; Chen, Wei J; Yang, Yen-Kuang; Yeh, Tzung-Lieh; Liao, Shin-Cheng; Lu, Ru-Band; Kuo, Po-Hsiu

2012-05-01

Personality traits have impacts on individuals' response to stress and mood expression. The current study aimed to investigate the profile of personality traits in patients with bipolar disorders and major depressive disorder (MDD). Familial aggregation of personality traits in mood disorder families was also evaluated. We recruited 260 clinical patients of MDD (92), bipolar disorder-I and II (BP-I=111, BP-II=57), 190 first-degree relatives, and 180 controls. Four personality traits were assessed using the Eysenck and Tridimensional Personality Questionnaires, including Extraversion (E), Neuroticism (N), Harm Avoidance (HA), and Novelty Seeking (NS). The magnitude of familiality of personality traits in mood disorder families was evaluated by mixed models and intra-class correlation coefficients (ICC). Patients with mood disorders had lower E, and higher N, HA and NS than controls. Unaffected relatives were not differed from controls in the four personality traits. BP-I had higher E, NS and lower N, HA than MDD patients (p<0.01). The scale N further distinguished BP-I from BP-II (p=0.02) with lower N among BP-I patients. There exhibited moderate familiality in E (ICC=0.184-0.239) and HA (ICC=0.355) in bipolar disorder families. Personality traits were accessed cross-sectionally without quantitatively controlled severity of mood symptoms. Different patterns of personality traits distinguish patients from unaffected individuals as well as separate diagnoses of mood disorders, indicating the usage of more comprehensive evaluation of personality traits in clinical settings. Familiality of extraversion and harm avoidance in bipolar disorder families provides insights for further investigating correlates of comorbid behavioral problems in bipolar disorders. Copyright © 2012 Elsevier B.V. All rights reserved.

Examining unanswered questions about the home environment and childhood obesity disparities using an incremental, mixed-methods, longitudinal study design: The Family Matters study.

PubMed

Berge, Jerica M; Trofholz, Amanda; Tate, Allan D; Beebe, Maureen; Fertig, Angela; Miner, Michael H; Crow, Scott; Culhane-Pera, Kathleen A; Pergament, Shannon; Neumark-Sztainer, Dianne

2017-11-01

There are disparities in the prevalence of childhood obesity for children from low-income and minority households. Mixed-methods studies that examine home environments in an in-depth manner are needed to identify potential mechanisms driving childhood obesity disparities that have not been examined in prior research. The Family Matters study aims to identify risk and protective factors for childhood obesity in low-income and minority households through a two-phased incremental, mixed-methods, and longitudinal approach. Individual, dyadic (i.e., parent/child; siblings), and familial factors that are associated with, or moderate associations with childhood obesity will be examined. Phase I includes in-home observations of diverse families (n=150; 25 each of African American, American Indian, Hispanic/Latino, Hmong, Somali, and White families). In-home observations include: (1) an interactive observational family task; (2) ecological momentary assessment of parent stress, mood, and parenting practices; (3) child and parent accelerometry; (4) three 24-hour child dietary recalls; (5) home food inventory; (6) built environment audit; (7) anthropometry on all family members; (8) an online survey; and (9) a parent interview. Phase I data will be used for analyses and to inform development of a culturally appropriate survey for Phase II. The survey will be administered at two time points to diverse parents (n=1200) of children ages 5-9. The main aim of the current paper is to describe the Family Matters complex study design and protocol and to report Phase I feasibility data for participant recruitment and study completion. Results from this comprehensive study will inform the development of culturally-tailored interventions to reduce childhood obesity disparities. Copyright © 2017 Elsevier Inc. All rights reserved.

Similar familial underpinnings for full and subsyndromal pediatric bipolar disorder: A familial risk analysis.

PubMed

Wozniak, Janet; Uchida, Mai; Faraone, Stephen V; Fitzgerald, Maura; Vaudreuil, Carrie; Carrellas, Nicholas; Davis, Jacqueline; Wolenski, Rebecca; Biederman, Joseph

2017-05-01

To examine the validity of subthreshold pediatric bipolar I disorder (BP-I), we compared the familial risk for BP-I in the child probands who had either full BP-I, subthreshold BP-I, ADHD, or were controls that neither had ADHD nor bipolar disorder. BP-I probands were youth aged 6-17 years meeting criteria for BP-I, full (N=239) or subthreshold (N=43), and also included were their first-degree relatives (N=687 and N=120, respectively). Comparators were youth with ADHD (N=162), controls without ADHD or bipolar disorder (N=136), and their first-degree relatives (N=511 and N=411, respectively). We randomly selected 162 non-bipolar ADHD probands and 136 non-bipolar, non-ADHD control probands of similar age and sex distribution to the BP-I probands from our case-control ADHD family studies. Psychiatric assessments were made by trained psychometricians using the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children Epidemiological Version (KSADS-E) and Structured Clinical Interview for DSM-IV (SCID) structured diagnostic interviews. We analyzed rates of bipolar disorder using multinomial logistic regression. Rates of full BP-I significantly differed between the four groups (χ 2 3 =32.72, P<.001): relatives of full BP-I probands and relatives of subthreshold BP-I probands had significantly higher rates of full BP-I than relatives of ADHD probands and relatives of control probands. Relatives of full BP-I, subthreshold BP-I, and ADHD probands also had significantly higher rates of major depressive disorder compared to relatives of control probands. Our results showed that youth with subthreshold BP-I had similarly elevated risk for BP-I and major depressive disorder in first-degree relatives as youth with full BP-I. These findings support the diagnostic continuity between subsyndromal and fully syndromatic states of pediatric BP-I disorder. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Deviation from the trans -Effect in Ligand-Exchange Reactions of Zeise’s Ions PtCl 3(C 2H 4) - with Heavier Halides (Br –, I - )

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hou, Gao-Lei; Govind, Niranjan; Xantheas, Sotiris S.

Four new Zeise’s family ions with mixed-halide ligands, i.e., PtCl nX 3-n(C 2H 4) - (X = Br, I; n = 1, 2), were synthesized via ligand-exchange reactions of KX salts with KPtCl 3(C 2H 4) in aqueous solutions, and were detected in vacuum via electrospray ionization mass spectrometry. Their photoelectron spectra reveal a series of well-resolved spectral peaks with their electron binding energies (EBEs) decreasing with increasing halide size, with I having a much stronger effect than Br, i.e., 4.57 (–Cl 3) > 4.56 (–Cl 2Br) > 4.53 (–ClBr 2) > 4.34 (–Cl 2I) > 4.30 eV (–ClI 2).more » Ab initio electronic structure calculations including spin-orbit coupling (SOC) predict that the cis- and trans-isomers are nearly isoenergetic with the cis-isomer for –Cl 2X, and the trans-isomer for –ClX 2 slightly favored, respectively. Excited-state spectra calculated with time-dependent density functional theory (TDDFT), and their comparison with the observed ones, suggest that for each species, both the cis- and trans-configurations coexist in the experiments and contribute to the observed spectra, a fact that clearly violates the prediction of the widely accepted trans-effect, which suggests that only one isomer would have formed.« less

Gene mutations in children with chronic pancreatitis.

PubMed

Witt, H

2001-01-01

In the last few years, several genes have been identified as being associated with hereditary and idiopathic chronic pancreatitis (CP), i.e. PRSS1, CFTR and SPINK1. In this study, we investigated 164 unrelated children and adolescents with CP for mutations in disease-associated genes by direct DNA sequencing, SSCP, RFLP and melting curve analysis. In 15 patients, we detected a PRSS1 mutation (8 with A16V, 5 with R122H, 2 with N29I), and in 34 patients, a SPINK1 mutation (30 with N34S, 4 with others). SPINK1 mutations were predominantly found in patients without a family history (29/121). Ten patients were homozygous for N34S, SPINK1 mutations were most common in 'idiopathic' CP, whereas patients with 'hereditary' CP predominantly showed a PRSS1 mutation (R122H, N29I). In patients without a family history, the most common PRSS1 mutation was A16V (7/121). In conclusion, our data suggest that CP may be inherited in a dominant, recessive or multigenetic manner as a result of mutations in the above-mentioned or as yet unidentified genes. This challenges the concept of idiopathic CP as a nongenetic disorder and the differentiation between hereditary and idiopathic CP. Therefore, we propose to classify CP as either 'primary CP' (with or without a family history) or 'secondary CP' caused by toxic, metabolic or other factors.

Deconvolution Methods for Multi-Detectors

DTIC Science & Technology

1989-08-30

in [7). We will say sometimes that the family of distributions jI,..,’m is strongly coprime. It might be useful to explain why is (4) called a...form g In the variable ?. given by n 3(11) g q(z~t,p):= 1 kz()(k k=1 Given a family of m entire holomorphic functions f n’*If m its zero set Z is defined...write g1 g jdk" Recall the k=l coefficients gi are holomorphic in both z and t. Let F be the vector valued holomorphic function F: - (f1 ’..’,f ) we

Identification of PSEN2 mutation p.N141I in Argentine pedigrees with early-onset familial Alzheimer's disease.

PubMed

Muchnik, Carolina; Olivar, Natividad; Dalmasso, María Carolina; Azurmendi, Pablo Javier; Liberczuk, Cynthia; Morelli, Laura; Brusco, Luis Ignacio

2015-10-01

Presenilin 2 gene (PSEN2) mutations account for <5% of all early-onset familial Alzheimer's disease (EOFAD) cases and only 13 have strong evidence for pathogenicity. We aimed to investigate the presence of PSEN2 mutation p.N141I and characterize the clinical phenotypes in 2 Argentine pedigrees (AR2 and AR3) with clinical symptoms of EOFAD. Detailed clinical assessments and genetic screening for PSEN2 and APOE genes were carried out in 19 individuals of AR2 and AR3 families. The p.N141I mutation was identified in all affected subjects and was associated with prominent early onset, rapidly progressive dementia, neurologic, and behavioral symptoms. AR2 and AR3 families share the same Volga German ancestry as all the families reported presenting this mutation. To our knowledge, this is the first report of PSEN2 mutation p.N141I in Argentina and even more, in South America. Our contribution increases the total number of described families carrying this mutation and help to improve the characterization of clinical phenotype in EOFAD associated to PSEN2 mutations. Copyright © 2015 Elsevier Inc. All rights reserved.

Novel polymeric LIT and divalent cation fast ion conducting materials

NASA Astrophysics Data System (ADS)

Angell, C. A.

Solid state energy devices require a component which conducts electricity by ionic migration. The conductivity of this element of the system must be very high. Four types of materials show the promise to provide the necessary conductivity characteristics, while offering other desirable features such as the ability to distort in shape under mechanical stresses: (1) crystalline; (2) plastic crystal; (3) inorganic glassy; and (4) polymer salt solutions. This document reports on the following materials: lead halide-containing fast ion conducting glasses (LiF-PbF2-Al(PO3)3), mixed ionic electronic conduction (Na2O-V2O5-TeO2), alpha relaxation in ionic glasses, glass transition in P2O2, and conductivity transition between all-halide and all-oxide glasses.

PHARMACOKINETICS OF N-BUTYL ACETATE AND ITS METABOLITES IN MALE SPRAGUE DAWLEY RATS AFTER INTRAVENOUS ADMINISTRATION

EPA Science Inventory

FAMILY APPROACH PBPK MODELING OF N-BUTYL ACETATE AND ITS METABOLITES IN MALE RATS
P.J. Deisinger1, J.G. Teeguarden2, H.A. Barton3, J.C. English1, W.D. Faber4, T.R. Tyler5, M.I. Banton6, M.E. Andersen7. 1Health & Environ. Laboratories., Eastman Kodak Company, Rochester, NY, USA...

2D Homologous Perovskites as Light-Absorbing Materials for Solar Cell Applications.

PubMed

Cao, Duyen H; Stoumpos, Constantinos C; Farha, Omar K; Hupp, Joseph T; Kanatzidis, Mercouri G

2015-06-24

We report on the fabrication and properties of the semiconducting 2D (CH3(CH2)3NH3)2(CH3NH3)(n-1)Pb(n)I(3n+1) (n = 1, 2, 3, and 4) perovskite thin films. The band gaps of the series decrease with increasing n values, from 2.24 eV (CH3(CH2)3NH3)2PbI4 (n = 1) to 1.52 eV CH3NH3PbI3 (n = ∞). The compounds exhibit strong light absorption in the visible region, accompanied by strong photoluminescence at room temperature, rendering them promising light absorbers for photovoltaic applications. Moreover, we find that thin films of the semi-2D perovskites display an ultrahigh surface coverage as a result of the unusual film self-assembly that orients the [Pb(n)I(3n+1)](-) layers perpendicular to the substrates. We have successfully implemented this 2D perovskite family in solid-state solar cells, and obtained an initial power conversion efficiency of 4.02%, featuring an open-circuit voltage (V(oc)) of 929 mV and a short-circuit current density (J(sc)) of 9.42 mA/cm(2) from the n = 3 compound. This result is even more encouraging considering that the device retains its performance after long exposure to a high-humidity environment. Overall, the homologous 2D halide perovskites define a promising class of stable and efficient light-absorbing materials for solid-state photovoltaics and other applications.

AMPA, NMDA and kainate glutamate receptor subunits are expressed in human peripheral blood mononuclear cells (PBMCs) where the expression of GluK4 is altered by pregnancy and GluN2D by depression in pregnant women.

PubMed

Bhandage, Amol K; Jin, Zhe; Hellgren, Charlotte; Korol, Sergiy V; Nowak, Krzysztof; Williamsson, Louise; Sundström-Poromaa, Inger; Birnir, Bryndis

2017-04-15

The amino acid glutamate opens cation permeable ion channels, the iGlu receptors. These ion channels are abundantly expressed in the mammalian brain where glutamate is the main excitatory neurotransmitter. The neurotransmitters and their receptors are being increasingly detected in the cells of immune system. Here we examined the expression of the 18 known subunits of the iGlu receptors families; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), kainate, N-methyl-d-aspartate (NMDA) and delta in human peripheral blood mononuclear cells (PBMCs). We compared the expression of the subunits between four groups: men, non-pregnant women, healthy pregnant women and depressed pregnant women. Out of 18 subunits of the iGlu receptors, mRNAs for 11 subunits were detected in PBMCs from men and non-pregnant women; AMPA: GluA3, GluA4, kainate: GluK2, GluK4, GluK5, NMDA: GluN1, GluN2C, GluN2D, GluN3A, GluN3B, and delta: GluD1. In the healthy and the depressed pregnant women, in addition, the delta GluD2 subunit was identified. The mRNAs for GluK4, GluK5, GluN2C and GluN2D were expressed at a higher level than other subunits. Gender, pregnancy or depression during pregnancy altered the expression of GluA3, GluK4, GluN2D, GluN3B and GluD1 iGlu subunit mRNAs. The greatest changes recorded were the lower GluA3 and GluK4 mRNA levels in pregnant women and the higher GluN2D mRNA level in healthy but not in depressed pregnant women as compared to non-pregnant individuals. Using subunit specific antibodies, the GluK4, GluK5, GluN1, GluN2C and GluN2D subunit proteins were identified in the PBMCs. The results show expression of specific iGlu receptor subunit in the PBMCs and support the idea of physiology-driven changes of iGlu receptors subtypes in the immune cells. Copyright © 2017 Elsevier B.V. All rights reserved.

Conversion of cassava wastes for biofertilizer production using phosphate solubilizing fungi.

PubMed

Ogbo, Frank C

2010-06-01

Two fungi characterized as Aspergillus fumigatus and Aspergillus niger, isolated from decaying cassava peels were used to convert cassava wastes by the semi-solid fermentation technique to phosphate biofertilizer. The isolates solubilized Ca(3)(PO(4))(2), AlPO(4) and FePO(4) in liquid Pikovskaya medium, a process that was accompanied by acid production. Medium for the SSF fermentation was composed of 1% raw cassava starch and 3% poultry droppings as nutrients and 96% ground (0.5-1.5mm) dried cassava peels as carrier material. During the 14days fermentation, both test organisms increased in biomass in this medium as indicated by increases in phosphatase activity and drop in pH. Ground cassava peels satisfied many properties required of carrier material particularly in respect of the organisms under study. Biofertilizer produced using A. niger significantly (p<.05) improved the growth of pigeon pea [Cajanus cajan (L.) Millsp.] in pot experiments but product made with A. fumigatus did not. Copyright 2009 Elsevier Ltd. All rights reserved.

Assessment of characteristics and remedial alternatives for abandoned mine drainage : case study at Staple Bend Tunnel unit of Allegheny Portage Railroad National Historic Site, Cambria County, Pennsylvania, 2004

USGS Publications Warehouse

Cravotta, Charles A.

2005-01-01

This report describes field, laboratory, and computational methods that could be used to assess remedial strategies for abandoned mine drainage (AMD). During April-June, 2004, the assessment process was applied to AMD from bituminous coal deposits at a test site in the Staple Bend Tunnel Unit of Allegheny Portage Railroad National Historic Site (ALPO-SBTU) in Cambria County, Pennsylvania. The purpose of this study was (1) to characterize the AMD quantity and quality within the ALPO-SBTU test site; (2) to evaluate the efficacy of limestone or steel slag for neutralization of the AMD on the basis of reaction-rate measurements; and (3) to identify possible alternatives for passive or active treatment of the AMD. The data from this case study ultimately will be used by the National Park Service (NPS) to develop a site remediation plan. The approach used in this study could be applicable at other sites subject to drainage from abandoned coal or metal mines.During April 2004, AMD from 9 sources (sites1, 1Fe, Fe, 2, 3, 3B, 5, 6, and 7) at the ALPO-SBTU test site had a combined flow rate of 1,420 gallons per minute (gal/min) and flow-weighted averages for pH of 3.3, net acidity of 55 milligrams per liter (mg/L) as CaCO3, and concentrations of dissolved sulfate, aluminum, iron, and manganese of 694 mg/L, 4.4 mg/L, 0.74 mg/L, and 1.2 mg/L, respectively. These pH, net acidity, sulfate, and aluminum values exceed effluent criteria for active mines in Pennsylvania.During April-June 2004, limestone and steel slag that were locally available were tested in the laboratory for their composition, approximate surface area, and potential to neutralize samples of the AMD. Although the substrates had a similar particle-size distribution and identical calcium content (43 percent as calcium oxide), the limestone was composed of crystalline carbonates and the slag was composed of silicate glass and minerals. After a minimum of 8 hours contact between the AMD and limestone or steel slag in closed containers (cubitainers), near-neutral effluent was produced. With prolonged contact between the AMD and limestone or steel slag, the concentrations of iron, aluminum, and most dissolved trace elements in effluent from the cubitainers declined while pH was maintained greater than 6.0 and less than 9.0. The cubitainer testing demonstrated (1) lower alkalinity production but higher pH of AMD treated with steel slag compared to limestone, and (2) predictable relations between the effluent quality, detention time, and corresponding flow rate and bulk volume for a bed of crushed limestone or steel slag in an AMD passive-treatment system.The process for evaluating AMD remedial strategies at the ALPO-SBTU test site involved the computation and ranking of the metal loadings during April 2004 for each of the AMD sources and a comparison of the data on AMD flow and chemistry (alkalinity, acidity, dissolved oxygen, ferric iron, aluminum) with published criteria for selection of passive-treatment technology. Although neutralization of the AMD by reaction with limestone was demonstrated with cubitainer tests, an anoxic limestone drain (ALD) was indicated as inappropriate for any AMD source at the test site because all had excessive concentrations of dissolved oxygen and (or) aluminum. One passive-treatment scenario that was identified for the individual or combined AMD sources involved an open limestone channel (OLC) to collect the AMD source(s), a vertical flow compost wetland (VFCW) to add alkalinity, and an aerobic wetland to facilitate iron and manganese oxidation and retention of precipitated solids. Innovative passive-system designs that direct flow upward through submerged layers of limestone and/or steel slag and that incorporate siphons for automatic flushing of solids to a pond also may warrant consideration. Alternatively, an active-treatment system with a hydraulic-powered lime doser could be employed instead of the VFCW or upflow system. Now, given these data on AMD flow and chemistry and identified remedial technologies, a resource manager can use a publicly available computer program such as "AMDTreat" to evaluate the potential sizes and costs of various remedial alternatives.

Concordance between patient and family reports of family functioning in bipolar I disorder and major depressive disorder.

PubMed

Weinstock, Lauren M; Wenze, Susan J; Munroe, Mary K; Miller, Ivan W

2013-05-01

Despite the extensive literature on family functioning and mood disorders, less is known about concordance between patient- and family-reported family functioning. To address this question, adults with bipolar I disorder (BD; n = 92) or major depressive disorder (MDD; n = 121) and their family members (n = 135 and 201, respectively) were recruited from hospital sources. All patients and their family members completed the Family Assessment Device (Epstein, Baldwin, Bishop. J Marital Fam Ther. 9:171-180, 1983). Intraclass correlation coefficients revealed that, in contrast to the moderate degree of concordance in the MDD sample, degree of concordance between patient- and family-reported family functioning was significantly weaker in BD. Subsequent analysis revealed that this discordance was driven by the reports of the child and young adolescent family members of the patients with BD. Results highlight the importance of collateral reports in the assessment of family functioning, especially among families of patients with BD, in research and treatment.

Environmental Baseline Survey Parcel E2, F, and I, Military Housing Areas Nellis Air Force Base, Nevada. Phase 1

DTIC Science & Technology

2011-09-01

SEP 2011 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Final Phase I Environmental Baseline Survey Parcel E2, F, and I...lead-based paint LUST leaking underground storage tank M.D.M. Mount Diablo Meridian MFH military family housing MHPI Military Housing...northwest OWS oil/water separator PADS PCB Activity Database PCB polychorinated biphenyl PCR Physical Condition Report PDF portable

Phase 1 Environmental Baseline Survey Parcels E2, F, and I, Military Housing Areas, Nellis Air Force Base, Nevada

DTIC Science & Technology

2011-09-01

21 SEP 2011 2. REPORT TYPE N/A 3. DATES COVERED 4. TITLE AND SUBTITLE Final Phase I Environmental Baseline Survey Parcels E2, F, and I...leaking underground storage tank M.D.M. Mount Diablo Meridian MFH military family housing MHPI Military Housing Privatization Initiative MSL...water separator PADS PCB Activity Database PCB polychorinated biphenyl PCR Physical Condition Report PDF portable document format PPV

Effects of Meditation-Based Stress Reduction in Younger Women with Breast Cancer

DTIC Science & Technology

1995-10-01

including history of exposure to estrogens, oral contraceptives, unusual menstrual problems). Family Health 2 • A-- S • • • ! • •• •M 6 History: history of...7 OWN 20. 0 1 an no more worried about my health than usualK -~~~ I lam worrded shout physical problem sumch as aches and pains ; or upset stomach; or...h ov e n a u s e a,. : 4 , 𔃽. Because of my ph~ysical condition, I hav trouble meeting the needai of my fandy 5 4 I have pain - 1 - 6. 1 am

Linguistic Validation of Interactive Educational Interventions in Neurologic Trauma.

PubMed

Sahyouni, Ronald; Mahmoodi, Amin; Tran, Diem K; Tran, Peter; Chen, Jefferson W

2017-11-01

Neurological surgeons oftentimes educate patients and their families on complex medical conditions and treatment options. Time constraints and varied linguistic and cultural backgrounds limit the amount of information that can be disbursed. In this study, we assessed the linguistic validity of interactive educational interventions in non-English-speaking patients with traumatic brain injury (TBI) and concussion and their families. A total of 273 English-, Spanish-, Korean-, and Vietnamese-speaking neurotrauma patients (n =124) and family members (n =149) completed a presurvey to evaluate their incipient understanding, interacted with an iPad-based iBook (Apple) on concussion or TBI in their native language, completed a postsurvey to gauge changes in understanding, and then consulted with their neurosurgeon. All participants (124 patients and 149 family members) had significantly increased (95% confidence interval [CI], P < 0.01) postsurvey scores (average pre-iBook score, 2.810; average post-iBook score, 4.109), regardless of native language or cultural background. Caucasian participants scored significantly higher than the combination of all ethnicities on both the baseline survey (95% CI, P < 0.01) and the post-iBook survey (95% CI, P < 0.01), and Asian participants scored significantly lower (95% CI, P < 0.05) than the combination regardless of similar baseline scores. Interactive iBook-based interventions on concussion and TBI can increase participants' comprehension, improve their comfort with their medical condition and the follow-up care, and enhance communication with their physicians. These findings are linguistically valid irrespective of the participants' native language or cultural background. Copyright © 2017 Elsevier Inc. All rights reserved.

Crystal Structures of the Glutamate Receptor Ion Channel GluK3 and GluK5 Amino-Terminal Domains

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kumar, Janesh; Mayer, Mark L.

2010-11-30

Ionotropic glutamate receptors (iGluRs) mediate the majority of fast excitatory synaptic neurotransmission in the central nervous system. The selective assembly of iGluRs into AMPA, kainate, and N-methyl-d-aspartic acid (NMDA) receptor subtypes is regulated by their extracellular amino-terminal domains (ATDs). Kainate receptors are further classified into low-affinity receptor families (GluK1-GluK3) and high-affinity receptor families (GluK4-GluK5) based on their affinity for the neurotoxin kainic acid. These two families share a 42% sequence identity for the intact receptor but only a 27% sequence identity at the level of ATD. We have determined for the first time the high-resolution crystal structures of GluK3 andmore » GluK5 ATDs, both of which crystallize as dimers but with a strikingly different dimer assembly at the R1 interface. By contrast, for both GluK3 and GluK5, the R2 domain dimer assembly is similar to those reported previously for other non-NMDA iGluRs. This observation is consistent with the reports that GluK4-GluK5 cannot form functional homomeric ion channels and require obligate coassembly with GluK1-GluK3. Our analysis also reveals that the relative orientation of domains R1 and R2 in individual non-NMDA receptor ATDs varies by up to 10{sup o}, in contrast to the 50{sup o} difference reported for the NMDA receptor GluN2B subunit. This restricted domain movement in non-NMDA receptor ATDs seems to result both from extensive intramolecular contacts between domain R1 and domain R2 and from their assembly as dimers, which interact at both R1 and R2 domains. Our results provide the first insights into the structure and function of GluK4-GluK5, the least understood family of iGluRs.« less

Rabbit macrophages secrete two biochemically and immunologically distinct endogenous pyrogens.

PubMed

Murphy, P A; Cebula, T A; Levin, J; Windle, B E

1981-10-01

Rabbit endogenous pyrogens occurred in two forms. One was an apparently single protein with a pI of 7.3; the other was a family of proteins with pI values of 4.5 to 5.0. We selected two of the latter, with pI values of 4.6 and 4.72, as representative of the group and compared them with the pI 7.3 pyrogen. Antisera raised in three goats completely neutralized the pyrogenic activity of the pI 7.3 pyrogen. Larger doses of these antisera did not block the pyrogenic activity of either of the pI 4.5 to 5.0 pyrogens. The pI 7.3 pyrogen contained a free --SH group which was essential to its biological activity. It was inactivated by 100 mM N-ethylmaleimide or 200 mM iodoacetamide, bound to Thiol-Sepharose columns, and could be eluted from them with mercaptoethanol. Neither of the pI 4.5 to 5.0 pyrogens was inactivated by N-ethylmaleimide or iodoacetamide, and neither bound to Thiol-Sepharose. Both endogenous pyrogens gave negative results in the Limulus lysate test for bacterial endotoxins. These results suggest that the pI 7.3 and pI 4.5 to 5.0 endogenous pyrogens are not closely related to each other and are consistent with the idea that they may not be related at all. Alternative hypotheses are discussed.

Rabbit macrophages secrete two biochemically and immunologically distinct endogenous pyrogens.

PubMed Central

Murphy, P A; Cebula, T A; Levin, J; Windle, B E

1981-01-01

Rabbit endogenous pyrogens occurred in two forms. One was an apparently single protein with a pI of 7.3; the other was a family of proteins with pI values of 4.5 to 5.0. We selected two of the latter, with pI values of 4.6 and 4.72, as representative of the group and compared them with the pI 7.3 pyrogen. Antisera raised in three goats completely neutralized the pyrogenic activity of the pI 7.3 pyrogen. Larger doses of these antisera did not block the pyrogenic activity of either of the pI 4.5 to 5.0 pyrogens. The pI 7.3 pyrogen contained a free --SH group which was essential to its biological activity. It was inactivated by 100 mM N-ethylmaleimide or 200 mM iodoacetamide, bound to Thiol-Sepharose columns, and could be eluted from them with mercaptoethanol. Neither of the pI 4.5 to 5.0 pyrogens was inactivated by N-ethylmaleimide or iodoacetamide, and neither bound to Thiol-Sepharose. Both endogenous pyrogens gave negative results in the Limulus lysate test for bacterial endotoxins. These results suggest that the pI 7.3 and pI 4.5 to 5.0 endogenous pyrogens are not closely related to each other and are consistent with the idea that they may not be related at all. Alternative hypotheses are discussed. PMID:7298180

Modulation by clamping: Kv4 and KChIP interactions.

PubMed

Wang, Kewei

2008-10-01

The rapidly inactivating (A-type) potassium channels regulate membrane excitability that defines the fundamental mechanism of neuronal functions such as pain signaling. Cytosolic Kv channel-interacting proteins KChIPs that belong to neuronal calcium sensor (NCS) family of calcium binding EF-hand proteins co-assemble with Kv4 (Shal) alpha subunits to form a native complex that encodes major components of neuronal somatodendritic A-type K+ current, I(SA), in neurons and transient outward current, I(TO), in cardiac myocytes. The specific binding of auxiliary KChIPs to the Kv4 N-terminus results in modulation of gating properties, surface expression and subunit assembly of Kv4 channels. Here, I attempt to emphasize the interaction between KChIPs and Kv4 based on recent progress made in understanding the structure complex in which a single KChIP1 molecule laterally clamps two neighboring Kv4.3 N-termini in a 4:4 manner. Greater insights into molecular mechanism between KChIPs and Kv4 interaction may provide therapeutic potentials of designing compounds aimed at disrupting the protein-protein interaction for treatment of membrane excitability-related disorders.

Fast and highly efficient SO2 capture by TMG immobilized on hierarchical micro-meso-macroporous AlPO-5/cordierite honeycomb ceramic materials.

PubMed

Xu, Jin; Zha, Xiaoling; Wu, Yumei; Ke, Qingping; Yu, Weifang

2016-05-11

SO2 capacity of the obtained TMG-AlPO-5/cordierite honeycomb ceramic (CHC) adsorbent was measured to be 1.13 mol per mol TMG. More importantly, compared with literature reported supported ionic liquids, it is featured by a significantly improved adsorption rate (t0.9 reduced from >30 min to ∼0.1 min) and negligible pressure drop.

Association of gestational weight gain expectations with advice on actual weight gain

USDA-ARS?s Scientific Manuscript database

To examine pregnant women's gestational weight gain expectations/advice from various sources (i.e., self, family/friends, physician) and the impact of these sources of expectations/advice on actual measured gestational weight gain. Pregnant women (n=230, 87.4% Caucasian, second pregnancy) in a cohor...

Hydroelectric reservoir inundation (Rio Madeira Basin, Amazon) and changes in traditional lifestyle: impact on growth and neurodevelopment of pre-school children.

PubMed

Marques, Rejane C; Dórea, José G; McManus, Concepta; Leão, Renata S; Brandão, Katiane G; Marques, Rayson C; Vieira, Igor H Ito; Guimarães, Jean-Remy D; Malm, Olaf

2011-04-01

To assess the dependence on fish consumption of families and its impact on nutritional status and neurodevelopment of pre-school children. Cross-sectional study that measured children's hair mercury (HHg) as an indicator of family fish consumption, growth (anthropometric Z-scores, WHO standards) and neurological (Gesell developmental scores (GDS)) development. Traditional living conditions among families residing in the area adjacent to the Samuel Dam (Western Amazon) hydroelectric reservoir. Two hundred and forty-nine pre-school children (1-59 months of age) from families transitioning from the traditional Amazonian lifestyle. Family fish consumption was significantly correlated with children's HHg concentration (Spearman's r=0.246, P<0.0001); however, HHg had no significant association with growth (Z-scores). Overall, the prevalence of severe malnutrition, i.e. stunting (height-for-age Z-score (HAZ)≤-3), underweight (weight-for-age Z-score (WAZ)≤-3) and wasting (weight-for-height Z-score (WHZ)≤-3) was 5.2% (n 13), 0% and 0.8% (n 2), respectively. The prevalence of moderate stunting (HAZ≥-3 to ≤-2), underweight (WAZ≥-3 to ≤-2) and wasting (WHZ≥-3 to ≤-2) was 8.8% (n 22), 2.4% (n 6) and 4.8% (n 12), respectively. Although 76% of the children showed adequate GDS (>85), multiple regression analysis showed that fish consumption (as HHg) had no impact on GDS, but that some variables did interact significantly with specific domains (motor and language development). The study showed that the families' shift in fish consumption had no negative impact on the growth of young children and that ensuing methylmercury exposure has not been a noticeable neurodevelopmental hindrance.

Family Relationships and the Psychosocial Adjustment of School-Aged Children in Intact Families

ERIC Educational Resources Information Center

Hakvoort, Esther M.; Bos, Henny M. W.; Van Balen, Frank; Hermanns, Jo M. A.

2010-01-01

The authors investigated whether the quality of three family relationships (i.e., marital, parent-child, sibling) in intact families are associated with each other and with children's psychosocial adjustment. Data were collected by means of maternal and child reports (N = 88) using standardized instruments (i.e., Marital Satisfaction Scale,…

The antiporter-like subunit constituent of the universal adaptor of complex I, group 4 membrane-bound [NiFe]-hydrogenases and related complexes.

PubMed

Batista, Ana P; Marreiros, Bruno C; Pereira, Manuela M

2013-05-01

We have recently investigated the long-recognized relationship between complex I and group 4 [NiFe] hydrogenases and we have established the so-called Energy-converting hydrogenase related (Ehr) complex as a new member of the family. We have also observed that four subunits, homologues to NuoB, D, H and L, are common to the members of the family. We have designated this common group of subunits the universal adaptor. Taking into account the similarity of the Na(+)/H(+) antiporter-like subunits of complex I (NuoL, NuoM and NuoN) and the unique structural characteristic of the long amphipathic α helix part of NuoL, the nature of the antiporter-like subunit of the universal adaptor was questioned. Thus, in this work we further explore the properties of the universal adaptor, investigating which antiporter-like subunit is part of the universal adaptor. We observe that the universal adaptor contains an antiporter-like subunit with a long amphipathic α helix, similar to NuoL. Consequently, the long helix is a common denominator that has been conserved in all members of the family. Such conservation surely reflects the key role of such helix in the energy transduction mechanism of this family of enzymes.

Family and Individual Predictors of First-Generation and Low Family Income First-Year Undergraduates' Integration at a Midwestern University

ERIC Educational Resources Information Center

Pilotte, Catherine

2012-01-01

This study examined how first-year undergraduates' family background characteristics (i.e., first-generation status and low family income) and individual attributes (i.e., sex, motivation, and best friend attachment) are related to institutional integration (faculty and student integration). Low and non-low family income students (N = 961)…

Siblings' Power and Influence in Polyadic Family Conflict During Early Childhood.

PubMed

Della Porta, Sandra; Howe, Nina

2017-06-01

This study examined sibling behavior during polyadic family conflicts (involving three or more family members) by identifying operational conflict elements (i.e., roles, topic), power strategies, effective influence of power, and social domain argumentation. Polyadic conflict sequences (n = 210) were identified in 35/39 families with two siblings (aged 4 and 6) and their parents observed at home. The dominant conflict topic, siblings' use of power and power strategy executed in relation to social domain argumentation, revealed unique qualities of conflict in the polyadic family context; effective use of power strategies to facilitate favorable outcomes differed by sibling birth order. Our account presents a nuanced view of the intricacies of polyadic family conflict, which provides unique opportunities for children's learning and socialization by siblings and parents. © 2017 Wiley Periodicals, Inc.

Can Knowledge of Client Birth Order Bias Clinical Judgment?

ERIC Educational Resources Information Center

Stewart, Allan E.

2004-01-01

Clinicians (N = 308) responded to identical counseling vignettes of a male client that differed only in the client's stated birth order. Clinicians developed different impressions about the client and his family experiences that corresponded with the prototypical descriptions of persons from 1 of 4 birth orders (i.e., first, middle, youngest, and…

All Prime Contract Awards by State or Country, Place, and Contractor, Fiscal Year 1985. Part 9 (Aberdeen, Maryland - Woodbine, Maryland).

DTIC Science & Technology

1985-01-01

W ’I-N004I NZ EOZ MUOIO N mU-4 mU. E- b MWoo M-O C ICOI N O4-0b O N40 N moNjO w-I-4-IOOO 000 0-I 0-I M-I mo m, (’I .44 c)4uu(O N - 00000 (I-CL) ON...4 -4 Of4 N-4-4.4-4-4-4 CM c-4 CM ~- I b In N. in Nv in- -( -4 N I Nl LN൴nNN NN I N 4 I IN In C, .’ I’- . -4 4 N4 N , - -4 -4 N NNNNN N4 N4- N0 . 4...00 0M ON4 0) 0- 0 0 0 0 04 IU :-41 N o N v - (4 N N ) N N N N NK r IN N4 00l~ b 04 C. 0i N ig) Ne le -00 Wn Gob O V 𔃺 0I0 - 4 04 M4 U) ( 0 4M Go( 00

Genome sequencing-assisted identification and the first functional validation of N-acyl-homoserine-lactone synthases from the Sphingomonadaceae family

PubMed Central

Gan, Han Ming; Dailey, Lucas K.; Halliday, Nigel; Williams, Paul; Hudson, André O.

2016-01-01

Background Members of the genus Novosphingobium have been isolated from a variety of environmental niches. Although genomics analyses have suggested the presence of genes associated with quorum sensing signal production e.g., the N-acyl-homoserine lactone (AHL) synthase (luxI) homologs in various Novosphingobium species, to date, no luxI homologs have been experimentally validated. Methods In this study, we report the draft genome of the N-(AHL)-producing bacterium Novosphingobium subterraneum DSM 12447 and validate the functions of predicted luxI homologs from the bacterium through inducible heterologous expression in Agrobacterium tumefaciens strain NTL4. We developed a two-dimensional thin layer chromatography bioassay and used LC-ESI MS/MS analyses to separate, detect and identify the AHL signals produced by the N. subterraneum DSM 12447 strain. Results Three predicted luxI homologs were annotated to the locus tags NJ75_2841 (NovINsub1), NJ75_2498 (NovINsub2), and NJ75_4146 (NovINsub3). Inducible heterologous expression of each luxI homologs followed by LC-ESI MS/MS and two-dimensional reverse phase thin layer chromatography bioassays followed by bioluminescent ccd camera imaging indicate that the three LuxI homologs are able to produce a variety of medium-length AHL compounds. New insights into the LuxI phylogeny was also gleemed as inferred by Bayesian inference. Discussion This study significantly adds to our current understanding of quorum sensing in the genus Novosphingobium and provide the framework for future characterization of the phylogenetically interesting LuxI homologs from members of the genus Novosphingobium and more generally the family Sphingomonadaceae. PMID:27635318

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1987. Part 7. Fairlane Gear, Incorporated-General Fiberglass Fabricators.

DTIC Science & Technology

1987-01-01

I N V4 (9 4 I D (9 ) -I m -I ) N0 -4 % r. 0 P.- 0 N D N N4 N N - n Y 04c l 4DJ N 0 N M N Nr AN40N "NN " eNC , % 1 (0 -I N N -I 0- I-4- N .I N N 4 4...EUW U w I uo u Z z x 04 0 Moto0 -4 I -4 -4 -4 N-EN -4 -t 4 --4 C. 𔃾 -4 -4-4 - ENC W- @0 m mm041I 0’ Cl) M’ C.) m’C)’ M170’ M’ @00o 0. on -4N cl N4N N1...X jNN, -INN -4 w. &M w 0 0 0 Ot -4 I ) .40 44. 44 .- 4 - ~ 4 4 -4 NNN a~ .4 W1 * CI000 I 0(000-4m 0n 00 00 - 0 0-I -- 0 0l 000.) 00-J 00..J)C) enC

Protection by Nigella sativa against carbon tetrachloride-induced downregulation of hepatic cytochrome P450 isozymes in rats.

PubMed

Ibrahim, Zein S; Ishizuka, Mayumi; Soliman, Mohamed; ElBohi, Khlood; Sobhy, Wageh; Muzandu, Kaampwe; Elkattawy, Azza M; Sakamoto, Kentaro Q; Fujita, Shoichi

2008-11-01

Nigella sativa (family Ranunculaceae) is an annual plant that has been traditionally used on the Indian subcontinent and in Middle Eastern countries. In this study, we investigated the effect of N. sativa oil on the drug-metabolizing cytochrome P450 (CYP) enzymes and whether it has a protective effect against the acute hepatotoxicity of CCl4. Intraperitoneal injection of rats with CCl4 drastically decreased CYP2E1, CYP2B, CYP3A2, CYP2C11, and CYP1A2 mRNA and protein expressions. Oral administration of 1 ml/kg N. sativa oil every day for one week prior to CCl4 injection alleviated CCl4-induced suppression of CYP2B, CYP3A2, CYP2C11, and CYP1A2. Moreover, CCl4 increased iNOS and TNFalpha mRNA, while N. sativa oil administration for one week prior to CCl4 injection downregulated the CCl4-induced iNOS mRNA and up-regulated IL-10 mRNA. These results indicate that N. sativa oil administration has a protective effect against the CCl4-mediated suppression of hepatic CYPs and that this protective effect is partly due to the downregulation of NO production and up-regulation of the anti-inflammatory IL-10.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 85. Part 13 (Mabco Prefabricated Bldg -Middletown Leather Co In).

DTIC Science & Technology

1985-01-01

04 C4 I4 C4I CNN NNN M.4f * N N N -4 -I .4 II.4NN *>-I w- C .40 C t In I, 0 I 1IC w040000oN 0 C4 . I CL 0. 0CZ in WI I )M nMI nIinn 00 CO(-ic.) I enC ...m I1 cNNL N ENC ’ 00 N N) N4 0(n MCI I C) 4 I -000r4 0 *.-0.- N~0 COJ cm mOi cl j C4 CMcj I ~ C)N NN 4~ Il N-.I-0I- 54-0 4 IU-4 1.I 4.I (I 4N - I ca c...40o 3X0 EN ENC , 3N 0 o-4 I-- EN" 0-4 1-400 MI 4 MO m)-I No 0 4- 0) (0 40 co In (o aU’Do Ml) 0 0 00 -4 -4 0 0 0 0 0 0 0 0 440)t M4 I n In In Ln -f 4 U

Influence of dopant substitution mechanism on catalytic properties within hierarchical architectures

PubMed Central

Newland, Stephanie H.; Sinkler, Wharton; Mezza, Thomas; Bare, Simon R.

2016-01-01

A range of hierarchically porous (HP) AlPO-5 catalysts, with isomorphously substituted transition metal ions, have been synthesized using an organosilane as a soft template. By employing a range of structural and spectroscopic characterization protocols, the properties of the dopant-substituted species within the HP architectures have been carefully evaluated. The resulting nature of the active site is shown to have a direct impact on the ensuing catalytic properties in the liquid-phase Beckmann rearrangement of cyclic ketones. PMID:27493563

Influence of dopant substitution mechanism on catalytic properties within hierarchical architectures

NASA Astrophysics Data System (ADS)

Newland, Stephanie H.; Sinkler, Wharton; Mezza, Thomas; Bare, Simon R.; Raja, Robert

2016-07-01

A range of hierarchically porous (HP) AlPO-5 catalysts, with isomorphously substituted transition metal ions, have been synthesized using an organosilane as a soft template. By employing a range of structural and spectroscopic characterization protocols, the properties of the dopant-substituted species within the HP architectures have been carefully evaluated. The resulting nature of the active site is shown to have a direct impact on the ensuing catalytic properties in the liquid-phase Beckmann rearrangement of cyclic ketones.

Birth order and psychopathology.

PubMed

Risal, Ajay; Tharoor, Hema

2012-07-01

Ordinal position the child holds within the sibling ranking of a family is related to intellectual functioning, personality, behavior, and development of psychopathology. To study the association between birth order and development of psychopathology in patients attending psychiatry services in a teaching hospital. Hospital-based cross-sectional study. Retrospective file review of three groups of patients was carried out. Patient-related variables like age of onset, birth order, family type, and family history of mental illness were compared with psychiatry diagnosis (ICD-10) generated. SPSS 13; descriptive statistics and one-way analysis of variance (ANOVA) were used. Mean age of onset of mental illness among the adult general psychiatry patients (group I, n = 527) was found to be 33.01 ± 15.073, while it was 11.68 ± 4.764 among the child cases (group II, n = 47) and 26.74 ± 7.529 among substance abuse cases (group III, n = 110). Among group I patients, commonest diagnosis was depression followed by anxiety and somatoform disorders irrespective of birth order. Dissociative disorders were most prevalent in the first born child (36.7%) among group II patients. Among group III patients, alcohol dependence was maximum diagnosis in all birth orders. Depression and alcohol dependence was the commonest diagnosis in adult group irrespective of birth order.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 88. Part 10. (Hitachi Instruments, Inc.-International Cordage, Inc.)

DTIC Science & Technology

1988-01-01

4 4 4- . 44" loo 1 n 1NN Nl Nl " 4 0 r- r- r-r- r 1% - r.r- lr-..-r Pr l ’)0014 I 0 󈧄V 1 0 󈧄V 100 (10 I " jci "ci C,1 l 1 1 74cI 0 N NNN N 0 N 0e...0N N* 4C N SN C4 C1 SN 1000 1I-C4N N N NNNN C4c jci ,qr N NN ON 0.N(4N U) N UCN ZN I-4N C ZN 1’o00000𔃾) 000000000-)00000000 0 030 0 Q 0 0 0 100 ...1n0.4 - l00om 4 4- 44 4- 4- -4 4 -4 - -4 -4 .- 4-4-1 .-- 4 4 -4 ) -4 lOONi nI I nI I nI i nI I f u,v)lUI u 11) -4 100 -4 m (1 c’) mm ) mMIM ) mM) M c

Concordance Between Patient and Family Reports of Family Functioning in Bipolar I Disorder and Major Depressive Disorder

PubMed Central

Weinstock, Lauren M.; Wenze, Susan J.; Munroe, Mary K.; Miller, Ivan W.

2013-01-01

Despite the extensive literature on family functioning and mood disorders, less is known about concordance between patient- and family-reported family functioning. To address this question, adults with bipolar I disorder (BD; n = 92), major depressive disorder (MDD; n = 121), and their family members (ns = 135 and 201, respectively) were recruited from hospital sources. All patients and their family members completed the Family Assessment Device (Epstein et al., 1983). Intraclass correlation coefficients revealed that, in contrast to the moderate degree of concordance in the MDD sample, degree of concordance between patient- and family-reported family functioning was significantly weaker in BD. Subsequent analysis revealed that this discordance was driven by the reports of the child and young adolescent family members of the patients with BD. Results highlight the importance of collateral reports in the assessment of family functioning, especially among families of patients with BD, in research and treatment. PMID:23588224

Multilevel Factor Analyses of Family Data from the Hawai'i Family Study of Cognition

ERIC Educational Resources Information Center

McArdle, John J.; Hamagami, Fumiaki; Bautista, Randy; Onoye, Jane; Hishinuma, Earl S.; Prescott, Carol A.; Takeshita, Junji; Zonderman, Alan B.; Johnson, Ronald C.

2014-01-01

In this study, we reanalyzed the classic Hawai'i Family Study of Cognition (HFSC) data using contemporary multilevel modeling techniques. We used the HFSC baseline data ("N" = 6,579) and reexamined the factorial structure of 16 cognitive variables using confirmatory (restricted) measurement models in an explicit sequence. These models…

Family Caregivers' Patterns of Positive and Negative Affect

ERIC Educational Resources Information Center

Robertson, Suzanne M.; Zarit, Steven H.; Duncan, Larissa G.; Rovine, Michael J.; Femia, Elia E.

2007-01-01

Stressful and positive family caregiving experiences were examined as predictors of caregivers' patterns of positive and negative affect in a sample of families providing care for a relative with dementia (N = 234). Four affect pattern groups were identified: (a) Well Adjusted (i.e., high positive affect, low negative affect); (b) Ambiguous (i.e.,…

Nanometer-scale mapping of irreversible electrochemical nucleation processes on solid Li-ion electrolytes

NASA Astrophysics Data System (ADS)

Kumar, Amit; Arruda, Thomas M.; Tselev, Alexander; Ivanov, Ilia N.; Lawton, Jamie S.; Zawodzinski, Thomas A.; Butyaev, Oleg; Zayats, Sergey; Jesse, Stephen; Kalinin, Sergei V.

2013-04-01

Electrochemical processes associated with changes in structure, connectivity or composition typically proceed via new phase nucleation with subsequent growth of nuclei. Understanding and controlling reactions requires the elucidation and control of nucleation mechanisms. However, factors controlling nucleation kinetics, including the interplay between local mechanical conditions, microstructure and local ionic profile remain inaccessible. Furthermore, the tendency of current probing techniques to interfere with the original microstructure prevents a systematic evaluation of the correlation between the microstructure and local electrochemical reactivity. In this work, the spatial variability of irreversible nucleation processes of Li on a Li-ion conductive glass-ceramics surface is studied with ~30 nm resolution. An increased nucleation rate at the boundaries between the crystalline AlPO4 phase and amorphous matrix is observed and attributed to Li segregation. This study opens a pathway for probing mechanisms at the level of single structural defects and elucidation of electrochemical activities in nanoscale volumes.

Nanometer-scale mapping of irreversible electrochemical nucleation processes on solid Li-ion electrolytes.

PubMed

Kumar, Amit; Arruda, Thomas M; Tselev, Alexander; Ivanov, Ilia N; Lawton, Jamie S; Zawodzinski, Thomas A; Butyaev, Oleg; Zayats, Sergey; Jesse, Stephen; Kalinin, Sergei V

2013-01-01

Electrochemical processes associated with changes in structure, connectivity or composition typically proceed via new phase nucleation with subsequent growth of nuclei. Understanding and controlling reactions requires the elucidation and control of nucleation mechanisms. However, factors controlling nucleation kinetics, including the interplay between local mechanical conditions, microstructure and local ionic profile remain inaccessible. Furthermore, the tendency of current probing techniques to interfere with the original microstructure prevents a systematic evaluation of the correlation between the microstructure and local electrochemical reactivity. In this work, the spatial variability of irreversible nucleation processes of Li on a Li-ion conductive glass-ceramics surface is studied with ~30 nm resolution. An increased nucleation rate at the boundaries between the crystalline AlPO4 phase and amorphous matrix is observed and attributed to Li segregation. This study opens a pathway for probing mechanisms at the level of single structural defects and elucidation of electrochemical activities in nanoscale volumes.

Nanometer-scale mapping of irreversible electrochemical nucleation processes on solid Li-ion electrolytes

PubMed Central

Kumar, Amit; Arruda, Thomas M.; Tselev, Alexander; Ivanov, Ilia N.; Lawton, Jamie S.; Zawodzinski, Thomas A.; Butyaev, Oleg; Zayats, Sergey; Jesse, Stephen; Kalinin, Sergei V.

2013-01-01

Electrochemical processes associated with changes in structure, connectivity or composition typically proceed via new phase nucleation with subsequent growth of nuclei. Understanding and controlling reactions requires the elucidation and control of nucleation mechanisms. However, factors controlling nucleation kinetics, including the interplay between local mechanical conditions, microstructure and local ionic profile remain inaccessible. Furthermore, the tendency of current probing techniques to interfere with the original microstructure prevents a systematic evaluation of the correlation between the microstructure and local electrochemical reactivity. In this work, the spatial variability of irreversible nucleation processes of Li on a Li-ion conductive glass-ceramics surface is studied with ~30 nm resolution. An increased nucleation rate at the boundaries between the crystalline AlPO4 phase and amorphous matrix is observed and attributed to Li segregation. This study opens a pathway for probing mechanisms at the level of single structural defects and elucidation of electrochemical activities in nanoscale volumes. PMID:23563856

Laser Scribed Graphene Cathode for Next Generation of High Performance Hybrid Supercapacitors.

PubMed

Lee, Seung-Hwan; Kim, Jin Hyeon; Yoon, Jung-Rag

2018-05-25

Hybrid supercapacitors have been regarded as next-generation energy storage devices due to their outstanding performances. However, hybrid supercapacitors remain a great challenge to enhance the energy density of hybrid supercapacitors. Herein, a novel approach for high-energy density hybrid supercapacitors based on a laser scribed graphene cathode and AlPO 4 -carbon hybrid coated H 2 Ti 12 O 25 (LSG/H-HTO) was designed. Benefiting from high-energy laser scribed graphene and high-power H-HTO, it was demonstrated that LSG/H-HTO delivers superior energy and power densities with excellent cyclability. Compared to previous reports on other hybrid supercapacitors, LSG/H-HTO electrode composition shows extraordinary energy densities of ~70.8 Wh/kg and power densities of ~5191.9 W/kg. Therefore, LSG/H-HTO can be regarded as a promising milestone in hybrid supercapacitors.

Prime Contractors with Awards Over $25,000 by Name, Location, and Contract Number. Fiscal Year 1993. (Lytron Incorporated-Quest Integrated). Part 4

DTIC Science & Technology

1994-03-01

I QQ Q 0 0 @ NN N@0 Q 0 Q QO a 0 (n . 4140 m 0 C-2 a %n mN N N ~ N N U 00 I 00 A 43N~ 4,11 VA 4y 0I a, *I a.f~ 0.0 a, a,4 a- 0 % 0N N (IA01.-4 Ca a...qoi ni 4V m I I I -4 .0 m m IN C : 101 C, 00N1 E II 4 A .4 IN U 0I1 0 Q N40 C44 NO .4 00 a0 0 114 Owa 06 0 0 I$ me 10-0 -0 0 001I . 4140 -IS 4 ’t 0601...4 I .4 -4 4 to -i 4 4~ a. .4 6 60 I414 ~ 4 6 64 1. CO 3 I5 I xi 1 1 4E M 4 t)c nA I ~ I 4* 4 .4 .~. I l44 40 44 1 43 1 1.4 44 . 4 46 4 44116 3~ 4140

Structure of the effector-binding domain of the arabinose repressor AraR from Bacillus subtilis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Procházková, Kateřina; Čermáková, Kateřina; Pachl, Petr

2012-02-01

The crystal structure of the effector-binding domain of the transcriptional repressor AraR from B. subtilis in complex with the effector molecule (l-arabinose) was determined at 2.2 Å resolution. A detailed analysis of the crystal identified a dimer organization that is distinctive from that of other members of the GalR/LacI family. In Bacillus subtilis, the arabinose repressor AraR negatively controls the expression of genes in the metabolic pathway of arabinose-containing polysaccharides. The protein is composed of two domains of different phylogenetic origin and function: an N-terminal DNA-binding domain belonging to the GntR family and a C-terminal effector-binding domain that shows similaritymore » to members of the GalR/LacI family. The crystal structure of the C-terminal effector-binding domain of AraR in complex with the effector l-arabinose has been determined at 2.2 Å resolution. The l-arabinose binding affinity was characterized by isothermal titration calorimetry and differential scanning fluorimetry; the K{sub d} value was 8.4 ± 0.4 µM. The effect of l-arabinose on the protein oligomeric state was investigated in solution and detailed analysis of the crystal identified a dimer organization which is distinctive from that of other members of the GalR/LacI family.« less

Plant sterol biosynthesis: identification of two distinct families of sterol 4alpha-methyl oxidases.

PubMed Central

Darnet, Sylvain; Rahier, Alain

2004-01-01

In plants, the conversion of cycloartenol into functional phytosterols requires the removal of the two methyl groups at C-4 by an enzymic complex including a sterol 4alpha-methyl oxidase (SMO). We report the cloning of candidate genes for SMOs in Arabidopsis thaliana, belonging to two distinct families termed SMO1 and SMO2 and containing three and two isoforms respectively. SMO1 and SMO2 shared low sequence identity with each other and were orthologous to the ERG25 gene from Saccharomyces cerevisiae which encodes the SMO. The plant SMO amino acid sequences possess all the three histidine-rich motifs (HX3H, HX2HH and HX2HH), characteristic of the small family of membrane-bound non-haem iron oxygenases that are involved in lipid oxidation. To elucidate the precise functions of SMO1 and SMO2 gene families, we have reduced their expression by using a VIGS (virus-induced gene silencing) approach in Nicotiana benthamiana. SMO1 and SMO2 cDNA fragments were inserted into a viral vector and N. benthamiana inoculated with the viral transcripts. After silencing with SMO1, a substantial accumulation of 4,4-dimethyl-9beta,19-cyclopropylsterols (i.e. 24-methylenecycloartanol) was obtained, whereas qualitative and quantitative levels of 4alpha-methylsterols were not affected. In the case of silencing with SMO2, a large accumulation of 4alpha-methyl-Delta7-sterols (i.e. 24-ethylidenelophenol and 24-ethyllophenol) was found, with no change in the levels of 4,4-dimethylsterols. These clear and distinct biochemical phenotypes demonstrate that, in contrast with animals and fungi, in photosynthetic eukaryotes, these two novel families of cDNAs are coding two distinct types of C-4-methylsterol oxidases controlling the level of 4,4-dimethylsterol and 4alpha-methylsterol precursors respectively. PMID:14653780

Analysis of the Structure and Function of FOX-4 Cephamycinase

PubMed Central

Lefurgy, S. T.; Malashkevich, V. N.; Aguilan, J. T.; Nieves, E.; Mundorff, E. C.; Biju, B.; Noel, M. A.; Toro, R.; Baiwir, D.; Papp-Wallace, K. M.; Almo, S. C.; Frere, J.-M.; Bou, G.

2015-01-01

Class C β-lactamases poorly hydrolyze cephamycins (e.g., cefoxitin, cefotetan, and moxalactam). In the past 2 decades, a new family of plasmid-based AmpC β-lactamases conferring resistance to cefoxitin, the FOX family, has grown to include nine unique members descended from the Aeromonas caviae chromosomal AmpC. To understand the basis for the unique cephamycinase activity in the FOX family, we determined the first X-ray crystal structures of FOX-4, apo enzyme and the acyl-enzyme with its namesake compound, cefoxitin, using the Y150F deacylation-deficient variant. Notably, recombinant expression of N-terminally tagged FOX-4 also yielded an inactive adenylylated enzyme form not previously observed in β-lactamases. The posttranslational modification (PTM), which occurs on the active site Ser64, would not seem to provide a selective advantage, yet might present an opportunity for the design of novel antibacterial drugs. Substantial ligand-induced changes in the enzyme are seen in the acyl-enzyme complex, particularly the R2 loop and helix H10 (P289 to N297), with movement of F293 by 10.3 Å. Taken together, this study provides the first picture of this highly proficient class C cephamycinase, uncovers a novel PTM, and suggests a possible cephamycin resistance mechanism involving repositioning of the substrate due to the presence of S153P, N289P, and N346I substitutions in the ligand binding pocket. PMID:26525784

Analysis of the Structure and Function of FOX-4 Cephamycinase.

PubMed

Lefurgy, S T; Malashkevich, V N; Aguilan, J T; Nieves, E; Mundorff, E C; Biju, B; Noel, M A; Toro, R; Baiwir, D; Papp-Wallace, K M; Almo, S C; Frere, J-M; Bou, G; Bonomo, R A

2016-02-01

Class C β-lactamases poorly hydrolyze cephamycins (e.g., cefoxitin, cefotetan, and moxalactam). In the past 2 decades, a new family of plasmid-based AmpC β-lactamases conferring resistance to cefoxitin, the FOX family, has grown to include nine unique members descended from the Aeromonas caviae chromosomal AmpC. To understand the basis for the unique cephamycinase activity in the FOX family, we determined the first X-ray crystal structures of FOX-4, apo enzyme and the acyl-enzyme with its namesake compound, cefoxitin, using the Y150F deacylation-deficient variant. Notably, recombinant expression of N-terminally tagged FOX-4 also yielded an inactive adenylylated enzyme form not previously observed in β-lactamases. The posttranslational modification (PTM), which occurs on the active site Ser64, would not seem to provide a selective advantage, yet might present an opportunity for the design of novel antibacterial drugs. Substantial ligand-induced changes in the enzyme are seen in the acyl-enzyme complex, particularly the R2 loop and helix H10 (P289 to N297), with movement of F293 by 10.3 Å. Taken together, this study provides the first picture of this highly proficient class C cephamycinase, uncovers a novel PTM, and suggests a possible cephamycin resistance mechanism involving repositioning of the substrate due to the presence of S153P, N289P, and N346I substitutions in the ligand binding pocket. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Dollar Summary of Prime Contract Awards by Contractor, State or Country, and Place, FY 85. Part 2 (D & A Construction - H & H Service Corpor).

DTIC Science & Technology

1985-01-01

4c4 ’n 8:r--t n0 . I L .I 0 In -4i n 0-1. :8:. 0 If In W I &n U) I I U UNS U g’-u U4 cc) I 040 0e a 6 e1 a. c C46, 4 C 1 00 t" .4 .. a4 4l f6 I. M t Co...1 a a - 0 -- - a44 ’ 0 Om 3"% am" aCCa - -1 aC- a amm m a t- I N N N m mCr- I4 a 21 - 0 I N C) C) c - " C) x C) x r.)mX a C -I c 0 = I= N -4 Noo W...0 aL NA aL N’-4’C 0-a Co -4 N N o 1 4 40- n N ) (DO4a *w w I-I )Ia m - 0Q’ CI "I "ao~ (.) (N 0 Z C-4 m 2lm acca -a: U 0 0 . I.- I.-1 I- nV -0LL J I I

Entanglement classification with algebraic geometry

NASA Astrophysics Data System (ADS)

Sanz, M.; Braak, D.; Solano, E.; Egusquiza, I. L.

2017-05-01

We approach multipartite entanglement classification in the symmetric subspace in terms of algebraic geometry, its natural language. We show that the class of symmetric separable states has the structure of a Veronese variety and that its k-secant varieties are SLOCC invariants. Thus SLOCC classes gather naturally into families. This classification presents useful properties such as a linear growth of the number of families with the number of particles, and nesting, i.e. upward consistency of the classification. We attach physical meaning to this classification through the required interaction length of parent Hamiltonians. We show that the states W N and GHZ N are in the same secant family and that, effectively, the former can be obtained in a limit from the latter. This limit is understood in terms of tangents, leading to a refinement of the previous families. We compute explicitly the classification of symmetric states with N≤slant4 qubits in terms of both secant families and its refinement using tangents. This paves the way to further use of projective varieties in algebraic geometry to solve open problems in entanglement theory.

Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Sets Technology Inc. - System/Technology Development). Part 17

DTIC Science & Technology

1994-03-01

00)0oN e4 N I cacao I -4N Y 4 .0 U)nendo4)0(0 0 00a) to U)(a I)0).Ř -4 i G I ) a)CV) 0 a)Nf4r0 0) 0to n 4- 4 44-N gV24 CqIt n0I I 0)0a coo 1 Ow 0 0 0...4 0 M0 W 0 0 0 W0.-4-4W-40 -40) -4 0 M flN MN T% N lc4M-4N 1. -0 -40(0)WG CO I cacao ) 11J0 -.100) ) N N ON NON-0 (0.-. -4 - - CO) -0)ON- X- N I000...c00 W -Nu 4Wf-C) IL -4 M LLa. N C 0 0 -4 -40 o z X4 0-4-.N U c 3000 K 4N qt NY N .N az zI cacao III N 0 O 0 Ca 0 00 N0z N O I 000 UM 0I 00 11L 400 4

All Prime Contract Awards by State or Country, Place and Contractor. Part 15. (Ada, Oklahoma-Zelienople, Pennsylvania)

DTIC Science & Technology

1989-01-01

N " l l 4C -440 W -4"< N ic>->-* X00 -AcN = N .CN .g(cwwwwwwwflf* Jc C .x((0Cl(0l* w NEI 0-40 N022 02 02 02 02 022222222 02 02Z222z don Z I a I I I I...de L) cc < M L- I.- H OcH 0 a 4c I.- I- 0.. 4- 4 -LIn WHIM N HO 0 z 0 cc z 0 0 40 Z HC I doN a 4-4 Woo Z 0)- @ 0 0 -- W 0 L- =40 1-4I 0 004N HO 9m- 4...4 - cv) Ia)OL o j n I.- N W I Cc r-4 If Z 00000CA4-W z if E I m) N4 10 ~ LA . . .L. LLIA.L. 0I 0 Nf m I doN N" " L)))))00000 mommmom’ -W u N 2 I

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 9. (H and H Meat Products, Inc.-Iannucci and Son Con.)

DTIC Science & Technology

1989-01-01

8217 Cl - 4 enC )() COOIn-Mi I -4N(r4 N(\\J C C NN N lc04-. >N I 40(00 000 0 (NJ>om -4N(04L) 1 00 CIoOC ’o >0 0 I 20 0 0 Q n4 00 0 L ooQC IM 4(-4 C4 o a oI...1- Q( a ɘ ə a < LA-L-L) < 00(u0N D 0( W1 I’N D (D (DN 41 If 4( c I lle W M.-(--4.1000 U).- 4(D LA- LADO LA4 ( (0C 01.᝴ L -4 - 14-4 I-4 -4 -- of...Mooɜ IftVci 0I oU1 n107,I nL nI nI CaN InC) LALLAALL L -4 1.1Q(0 O C1(1Cim 1000 -00 1 f (D(0 f1 ENc nu nI nu )t nL)I r nI nu O L A L A L A L 10 C -i

Improving Childhood Asthma Outcomes in the United States. A Blueprint for Policy Action

DTIC Science & Technology

2002-01-01

would include family physicians, pediatricians, nurse practitioners, respiratory therapists, and pharmacists . Based on the NHLBI National Guidelines...C_4_C4_M_ In I ( Zf~qpqrsaJ JO -3 U! %L9 dol ul -0 -: L ’ V 11’ r-: m.N 12 .-- -1 ’ m m r 0 In 00 - UTIU~lSJO Uj~TE E)()SOS~Ip~UtIJ%9diU tITUIflS OJ UTI ~E ~a

Whole genome sequencing enables the characterization of BurI, a LuxI homologue of Burkholderia cepacia strain GG4

PubMed Central

Hong, Kar Wai; Chan, Kok-Gan

2015-01-01

Quorum sensing is a mechanism for regulating proteobacterial gene expression in response to changes in cell population. In proteobacteria, N-acyl homoserine lactone (AHL) appears to be the most widely used signalling molecules in mediating, among others, the production of extracellular virulence factors for survival. In this work, the genome of B. cepacia strain GG4, a plasmid-free strain capable of AHL synthesis was explored. In silico analysis of the 6.6 Mb complete genome revealed the presence of a LuxI homologue which correspond to Type I quorum sensing. Here, we report the molecular cloning and characterization of this LuxI homologue, designated as BurI. This 609 bp gene was cloned and overexpressed in Escherichia coli BL21(DE3). The purified protein was approximately 25 kDa and is highly similar to several autoinducer proteins of the LuxI family among Burkholderia species. To verify the AHL synthesis activity of this protein, high resolution liquid chromatography-mass spectrometry analysis revealed the production of 3-oxo-hexanoylhomoserine lactone, N-octanoylhomoserine lactone and 3-hydroxy-octanoylhomoserine lactone from induced E. coli BL21 harboring the recombinant BurI. Our data show, for the first time, the cloning and characterization of the LuxI homologue from B. cepacia strain GG4 and confirmation of its AHL synthesis activity. PMID:26290785

Limited Quantum Helium Transportation through Nano-channels by Quantum Fluctuation

PubMed Central

Ohba, Tomonori

2016-01-01

Helium at low temperatures has unique quantum properties such as superfluidity, which causes it to behave differently from a classical fluid. Despite our deep understanding of quantum mechanics, there are many open questions concerning the properties of quantum fluids in nanoscale systems. Herein, the quantum behavior of helium transportation through one-dimensional nanopores was evaluated by measuring the adsorption of quantum helium in the nanopores of single-walled carbon nanohorns and AlPO4-5 at 2–5 K. Quantum helium was transported unimpeded through nanopores larger than 0.7 nm in diameter, whereas quantum helium transportation was significantly restricted through 0.4-nm and 0.6-nm nanopores. Conversely, nitrogen molecules diffused through the 0.4-nm nanopores at 77 K. Therefore, quantum helium behaved as a fluid comprising atoms larger than 0.4–0.6 nm. This phenomenon was remarkable, considering that helium is the smallest existing element with a (classical) size of approximately 0.27 nm. This finding revealed the presence of significant quantum fluctuations. Quantum fluctuation determined the behaviors of quantum flux and is essential to understanding unique quantum behaviors in nanoscale systems. PMID:27363671

Lindeberg theorem for Gibbs-Markov dynamics

NASA Astrophysics Data System (ADS)

Denker, Manfred; Senti, Samuel; Zhang, Xuan

2017-12-01

A dynamical array consists of a family of functions \\{ fn, i: 1≤slant i≤slant k_n, n≥slant 1\\} and a family of initial times \\{τn, i: 1≤slant i≤slant k_n, n≥slant 1\\} . For a dynamical system (X, T) we identify distributional limits for sums of the form for suitable (non-random) constants s_n>0 and an, i\\in { R} . We derive a Lindeberg-type central limit theorem for dynamical arrays. Applications include new central limit theorems for functions which are not locally Lipschitz continuous and central limit theorems for statistical functions of time series obtained from Gibbs-Markov systems. Our results, which hold for more general dynamics, are stated in the context of Gibbs-Markov dynamical systems for convenience.

Biosynthesis of truncated N-linked oligosaccharides results from non-orthologous hexosaminidase-mediated mechanisms in nematodes, plants, and insects.

PubMed

Gutternigg, Martin; Kretschmer-Lubich, Dorothea; Paschinger, Katharina; Rendić, Dubravko; Hader, Josef; Geier, Petra; Ranftl, Ramona; Jantsch, Verena; Lochnit, Günter; Wilson, Iain B H

2007-09-21

In many invertebrates and plants, the N-glycosylation profile is dominated by truncated paucimannosidic N-glycans, i.e. glycans consisting of a simple trimannosylchitobiosyl core often modified by core fucose residues. Even though they lack antennal N-acetylglucosamine residues, the biosynthesis of these glycans requires the sequential action of GlcNAc transferase I, Golgi mannosidase II, and, finally, beta-N-acetylglucosaminidases. In Drosophila, the recently characterized enzyme encoded by the fused lobes (fdl) gene specifically removes the non-reducing N-acetylglucosamine residue from the alpha1,3-antenna of N-glycans. In the present study, we examined the products of five beta-N-acetylhexosaminidase genes from Caenorhabditis elegans (hex-1 to hex-5, corresponding to reading frames T14F9.3, C14C11.3, Y39A1C.4, Y51F10.5, and Y70D2A.2) in addition to three from Arabidopsis thaliana (AtHEX1, AtHEX2, and AtHEX3, corresponding to reading frames At1g65590, At3g55260, and At1g05590). Based on homology, the Caenorhabditis HEX-1 and all three Arabidopsis enzymes are members of the same sub-family as the aforementioned Drosophila fused lobes enzyme but either act as chitotriosidases or non-specifically remove N-acetylglucosamine from both N-glycan antennae. The other four Caenorhabditis enzymes are members of a distinct sub-family; nevertheless, two of these enzymes displayed the same alpha1,3-antennal specificity as the fused lobes enzyme. Furthermore, a deletion of part of the Caenorhabditis hex-2 gene drastically reduces the native N-glycan-specific hexosaminidase activity in mutant worm extracts and results in a shift in the N-glycan profile, which is a demonstration of its in vivo enzymatic relevance. Based on these data, it is hypothesized that the genetic origin of paucimannosidic glycans in nematodes, plants, and insects involves highly divergent members of the same hexosaminidase gene family.

All Prime Contract Awards by State or Country, Place, and Contractor, FY 88. Part 14. (Aberdeen, North Carolina-Zanesville, Ohio)

DTIC Science & Technology

1988-01-01

a) > fr wUO wua w U.1 W 0 w 0C(00O-4 C 0 a. W(1 La- 0--cl - (n U, -.1 i.* .- " I,.1- wI- 44 Z(0(01- C(0.-4 l(0 w0 1-0 co 0Nz W 00 W(1-lZ Cr-Z um1 00...l N N l N 1 N N-4.-4 ’-4-4.-IN -4 1 00r- I Nl NI N1 N" -4-4 C1 "NNNli- I01( Q L I 1 -4 -4 - 4 -4 fr -- CNNN U) 100’V I I1Q000 I N N1 -4 -4 N4 N 04NN...4 .- 4 . 4 4- I 00(0 I C~ -r- I- r 0-r-r.r- fr - l P- Qr- r- or- ar- >J- >j- >,t- r- r- r- . DO(0 o ’n I4400000 40000000 1000 440 m0 m 0 mU0

Purification and characterization of gigantoxin-4, a new actinoporin from the sea anemone Stichodactyla gigantea.

PubMed

Hu, Bo; Guo, Wei; Wang, Liang-Hua; Wang, Jian-Guang; Liu, Xiao-Yu; Jiao, Bing-Hua

2011-01-01

A new Cytolysin, termed as Gigantoxin-4, was isolated from the sea anemone Stichodactyla gigantea and found to be highly homologous with Cytolysin-3 (HMg III) from Heteractis magnifica, RTX-A from Radianthus macrodactylus, and Sticholysin-1 (St I) and Sticholysin-2 (St II) from Stichodactyla helianthus (homology 82%, 86%, 82% and 86% respectively). Its 20 N-terminal residues were identified and the full-length cDNA sequence was obtained by reverse transcription-polymerase chain reaction (RT-PCR). Multiple sequence alignments with other Cytolysins of the actinoporin family clearly indicated that Gigantoxin-4 belongs to this protein family. SDS-PAGE electrophoresis showed that this new actinoporin had a molecular mass of about 19 kDa, and possessed a high hemolytic activity to human erythrocytes (HA(50)= 40 ng/ml), which was inhibited by pre-incubation with sphingomyelin (SM) or SM-cholesterol mixtures. Our in vivo experiments showed that Gigantoxin-4 had wide toxicity to the rat cardiovascular system and the respiratory system. A concentration of 30 μg/kg Gigantoxin-4, i.v. produced a positive inotropic effect on the rat heart although final cardiovascular failure was inevitable, and 60 μg/kg Gigantoxin-4 caused respiratory arrest rapidly resulting in rat death. HE staining indicated pathological changes in various organs and tissues after i.v. administration of Gigantoxin-4.

Selected vitamin D metabolic gene variants and risk for autism spectrum disorder in the CHARGE Study.

PubMed

Schmidt, Rebecca J; Hansen, Robin L; Hartiala, Jaana; Allayee, Hooman; Sconberg, Jaime L; Schmidt, Linda C; Volk, Heather E; Tassone, Flora

2015-08-01

Vitamin D is essential for proper neurodevelopment and cognitive and behavioral function. We examined associations between autism spectrum disorder (ASD) and common, functional polymorphisms in vitamin D pathways. Children aged 24-60 months enrolled from 2003 to 2009 in the population-based CHARGE case-control study were evaluated clinically and confirmed to have ASD (n=474) or typical development (TD, n=281). Maternal, paternal, and child DNA samples for 384 (81%) families of children with ASD and 234 (83%) families of TD children were genotyped for: TaqI, BsmI, FokI, and Cdx2 in the vitamin D receptor (VDR) gene, and CYP27B1 rs4646536, GC rs4588, and CYP2R1 rs10741657. Case-control logistic regression, family-based log-linear, and hybrid log-linear analyses were conducted to produce risk estimates and 95% confidence intervals (CI) for each allelic variant. Paternal VDR TaqI homozygous variant genotype was significantly associated with ASD in case-control analysis (odds ratio [OR] [CI]: 6.3 [1.9-20.7]) and there was a trend towards increased risk associated with VDR BsmI (OR [CI]: 4.7 [1.6-13.4]). Log-linear triad analyses detected parental imprinting, with greater effects of paternally-derived VDR alleles. Child GC AA-genotype/A-allele was associated with ASD in log-linear and ETDT analyses. A significant association between decreased ASD risk and child CYP2R1 AA-genotype was found in hybrid log-linear analysis. There were limitations of low statistical power for less common alleles due to missing paternal genotypes. This study provides preliminary evidence that paternal and child vitamin D metabolism could play a role in the etiology of ASD; further research in larger study populations is warranted. Copyright © 2015. Published by Elsevier Ireland Ltd.

Alpha List of Prime Contract Awards. Oct 91 - Sep 92. FY 92. (Mill Distributors Inc - North Bay Contracting)

DTIC Science & Technology

1993-01-01

4 m Cl) (1) a-4-4 (D C4 el im E~-ZN 0 0 -4 m IM mnif-4p0 to 410 0)N" 3 WWLIJ.1- a 0 0 0 0C00, 0C00. 0N 0-4-4 a > 2 Z -II 0-4o a ILI in1 a 000i N 2 2...4440 4I- 4(0 aN 4(0 LL 4(Z0IU A w N 04 I (0ON 442 ac 44~II4--. de wZZ~ ~ w2 . w( w0 w: CA: - Ř- 4. ( 00-4 9 4 w i w t 4 4-41(00 a-4 _j4 4 i-i - j j...0 0 0 0L U Imo 000 Ul NNNN N N V -IN NN N NN N N1 N W I WO0N U 0 0 U) a 1 0040N N 0 j0 de It 00 I ID 01- < 0 -C 0 4c ម coo lia 32 I.- I-. - a. I

A four-culture study of self-enhancement and adjustment using the social relations model: do alternative conceptualizations and indices make a difference?

PubMed

Church, A Timothy; Katigbak, Marcia S; Mazuera Arias, Rina; Rincon, Brigida Carolina; Vargas-Flores, José de Jesús; Ibáñez-Reyes, Joselina; Wang, Lei; Alvarez, Juan M; Wang, Congcong; Ortiz, Fernando A

2014-06-01

In the self-enhancement literature, 2 major controversies remain--whether self-enhancement is a cultural universal and whether it is healthy or maladaptive. Use of the social relations model (SRM; Kenny, 1994) might facilitate resolution of these controversies. We applied the SRM with a round-robin design in both friend and family contexts in 4 diverse cultures: the United States (n = 399), Mexico (n = 413), Venezuela (n = 290), and China (n = 222). Results obtained with social comparison, self-insight, and SRM conceptualizations and indices of self-enhancement were compared for both agentic traits (i.e., egoistic bias) and communal traits (i.e., moralistic bias). Conclusions regarding cultural differences in the prevalence of self-enhancement vs. self-effacement tendencies, and the relationship between self-enhancement and adjustment, varied depending on the index of self-enhancement used. For example, consistent with cultural psychology perspectives, Chinese showed a greater tendency to self-efface than self-enhance using social comparison and self-insight indices, particularly on communal traits in the friend context. However, no cultural differences were observed when perceiver and target effects were controlled using the SRM indices. In all cultures, self-enhancement indices were moderately consistent across friend and family contexts, suggesting traitlike tendencies. To a similar extent in all 4 cultures, self-enhancement tendencies, as measured by the SRM indices, were moderately related to self-rated adjustment, but unrelated, or less so, to observer-rated adjustment.

A family of models of partially relaxed stellar systems. I. Dynamical properties

NASA Astrophysics Data System (ADS)

Trenti, M.; Bertin, G.

2005-01-01

Recently we have found that a family of models of partially relaxed, anisotropic stellar systems, inspired earlier by studies of incomplete violent relaxation, exhibits some interesting thermodynamic properties. Here we present a systematic investigation of its dynamical characteristics, in order to establish the basis for a detailed comparison with simulations of collisionless collapse, planned for a separate paper. For a full comparison with the observations of elliptical galaxies, the models should be extended to allow for the presence a sizable dark halo and of significant rotation. In the spherical limit, the family is characterized by two dimensionless parameters, i.e. Ψ, measuring the depth of the galaxy potential, and ν, defining the form of a third global quantity Q, which is argued to be approximately conserved during collisionless collapse (in addition to the total energy and the total number of stars). The family of models is found to have the following properties. The intrinsic density profile beyond the half-mass radius r_M is basically universal and independent of Ψ. The projected density profiles are well fitted by the R1/n law, with n ranging from 2.5 to 8.5, dependent on Ψ, with n close to 4 for concentrated models. All models exhibit radial anisotropy in the pressure tensor, especially in their outer parts, already significant at r ≈ r_M. At fixed values of ν, models with lower Ψ are more anisotropic; at fixed values of Ψ, models with lower ν are more concentrated and more anisotropic. When the global amount of anisotropy, measured by 2K_r/K_T, is large, the models are unstable with respect to the radial-orbit instability; still, a wide region of parameter space (i.e., sufficiently high values of Ψ, for ν > 3/8) is covered by models that are dynamically stable; for these, the line profiles (line-of-sight velocity distribution) are Gaussian at the 5% level, with a general trend of positive values of h_4 at radii larger than the effective radius R_e.

Prime Contract Awards by State or Country, Place and Contractor. Part 9 (Dundalk, Maryland - Roseville, Michigan), FY1991

DTIC Science & Technology

1991-01-01

0 0 0 400 100 C 0 00 C* -I 04 U )L - )IN ) IL OOOOOON S. N N N N N N NN-N * L).-I.-4 zzzzz2zzzzZZ 2 Z 2 2 ZZ zzz U-I 0-m MI4444444 0 N N 00C4o<N 0NI0...1 Co-I me WL-4 -4--4-44-4 -4 -4 -4-4 -4 -4 W40 (1N 1-0 -4.1 I-aInan CL.-IC) ne me A2 I o- - 100 00.- me D.. o o 00 0 o oo0oo00o 0 &)0 A (no 40, aO o0...oln o-4)- 411 U)0. In). 10 InI n ca if d I N w ~ (D< a4C N 4 M0 3 4 0 4- I3l 44 XCi X’ c"Il _C44 a-I 0Cl M-i ’in if 100 - -2 N D 00 1- 0 1-) 1 00 1

An Ionic Liquid Reaction and Separation Process for Production of Hydroxymethylfurfural from Sugars

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Wei; Zheng, Feng; Li, Joanne

2014-01-01

There has been world-wide interest to making plastics out of renewable biomass feedstock for recent years. Hydroxymethylfurfural (HMF) is viewed as an attractive alternate to terephthalic acid (TPA) for production of polyesters (PET) and polyamides. Conversion of sugars into HMF has been studied in numerous publications. In this work, a complete ionic liquid reaction and separation process is presented for nearly stoichiometric conversion of fructose into HMF. Different adsorbent materials are evaluated and silicalite material is demonstrated effective for isolation of 99% pure HMF from actual ionic liquid reaction mixtures and for recovery of the un-converted sugars and reaction intermediatemore » along with the ionic liquid. Membrane-coated silicalite particles are prepared and studied for a practical adsorption process operated at low pressure drops but with separation performances comparable or better than the powder material. Complete conversion of fresh fructose feed into HMF in the recycled ionic liquid is shown under suitable reaction conditions. Stability of HMF product is characterized. A simplified process flow diagram is proposed based on these research results, and the key equipment such as reactor and adsorbent bed is sized for a plant of 200,000 ton/year of fructose processing capacity. The proposed HMF production process is much simpler than the current paraxylene (PX) manufacturing process from petroleum oil, which suggests substantial reduction to the capital cost and energy consumption be possible. At the equivalent value to PX on the molar basis, there can be a large gross margin for HMF production from fructose and/or sugars.« less

Three-dimensional rotation electron diffraction: software RED for automated data collection and data processing

PubMed Central

Wan, Wei; Sun, Junliang; Su, Jie; Hovmöller, Sven; Zou, Xiaodong

2013-01-01

Implementation of a computer program package for automated collection and processing of rotation electron diffraction (RED) data is described. The software package contains two computer programs: RED data collection and RED data processing. The RED data collection program controls the transmission electron microscope and the camera. Electron beam tilts at a fine step (0.05–0.20°) are combined with goniometer tilts at a coarse step (2.0–3.0°) around a common tilt axis, which allows a fine relative tilt to be achieved between the electron beam and the crystal in a large tilt range. An electron diffraction (ED) frame is collected at each combination of beam tilt and goniometer tilt. The RED data processing program processes three-dimensional ED data generated by the RED data collection program or by other approaches. It includes shift correction of the ED frames, peak hunting for diffraction spots in individual ED frames and identification of these diffraction spots as reflections in three dimensions. Unit-cell parameters are determined from the positions of reflections in three-dimensional reciprocal space. All reflections are indexed, and finally a list with hkl indices and intensities is output. The data processing program also includes a visualizer to view and analyse three-dimensional reciprocal lattices reconstructed from the ED frames. Details of the implementation are described. Data collection and data processing with the software RED are demonstrated using a calcined zeolite sample, silicalite-1. The structure of the calcined silicalite-1, with 72 unique atoms, could be solved from the RED data by routine direct methods. PMID:24282334

Three-dimensional rotation electron diffraction: software RED for automated data collection and data processing.

PubMed

Wan, Wei; Sun, Junliang; Su, Jie; Hovmöller, Sven; Zou, Xiaodong

2013-12-01

Implementation of a computer program package for automated collection and processing of rotation electron diffraction (RED) data is described. The software package contains two computer programs: RED data collection and RED data processing. The RED data collection program controls the transmission electron microscope and the camera. Electron beam tilts at a fine step (0.05-0.20°) are combined with goniometer tilts at a coarse step (2.0-3.0°) around a common tilt axis, which allows a fine relative tilt to be achieved between the electron beam and the crystal in a large tilt range. An electron diffraction (ED) frame is collected at each combination of beam tilt and goniometer tilt. The RED data processing program processes three-dimensional ED data generated by the RED data collection program or by other approaches. It includes shift correction of the ED frames, peak hunting for diffraction spots in individual ED frames and identification of these diffraction spots as reflections in three dimensions. Unit-cell parameters are determined from the positions of reflections in three-dimensional reciprocal space. All reflections are indexed, and finally a list with hkl indices and intensities is output. The data processing program also includes a visualizer to view and analyse three-dimensional reciprocal lattices reconstructed from the ED frames. Details of the implementation are described. Data collection and data processing with the software RED are demonstrated using a calcined zeolite sample, silicalite-1. The structure of the calcined silicalite-1, with 72 unique atoms, could be solved from the RED data by routine direct methods.

Synthesis of mesoporous zeolite single crystals with cheap porogens

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tao Haixiang; Li Changlin; Ren Jiawen

2011-07-15

Mesoporous zeolite (silicalite-1, ZSM-5, TS-1) single crystals have been successfully synthesized by adding soluble starch or sodium carboxymethyl cellulose (CMC) to a conventional zeolite synthesis system. The obtained samples were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), nitrogen sorption analysis, {sup 27}Al magic angle spinning nuclear magnetic resonance ({sup 27}Al MAS NMR), temperature-programmed desorption of ammonia (NH{sub 3}-TPD) and ultraviolet-visible spectroscopy (UV-vis). The SEM images clearly show that all zeolite crystals possess the similar morphology with particle size of about 300 nm, the TEM images reveal that irregular intracrystalmore » pores are randomly distributed in the whole crystal. {sup 27}Al MAS NMR spectra indicate that nearly all of the Al atoms are in tetrahedral co-ordination in ZSM-5, UV-vis spectra confirm that nearly all of titanium atoms are incorporated into the framework of TS-1. The catalytic activity of meso-ZSM-5 in acetalization of cyclohexanone and meso-TS-1 in hydroxylation of phenol was also studied. The synthesis method reported in this paper is cost-effective and environmental friendly, can be easily expended to prepare other hierarchical structured zeolites. - Graphical abstract: Mesoporous zeolite single crystals were synthesized by using cheap porogens as template. Highlights: > Mesoporous zeolite (silicalite-1, ZSM-5, TS-1) single crystals were synthesized. > Soluble starch or sodium carboxymethyl cellulose (CMC) was used as porogens. > The mesoporous zeolites had connected mesopores although closed pores existed. > Higher catalytic activities were obtained.« less

Disease, disorder, or deception? Latah as habit in a Malay extended family.

PubMed

Bartholomew, R E

1994-06-01

Thirty-seven cases of latah are examined within the author's Malay extended family (N = 115). Based on ethnographic data collected and a literature review, cases are readily divisible into two broad categories: habitual (N = 33) and performance (N = 4). The first form represents an infrequent, culturally conditioned habit that is occasionally used as a learned coping strategy in the form of a cathartic stress response to sudden startle with limited secondary benefits (i.e., exhibiting brief verbal obscenity with impunity). In this sense, it is identical to Western swearing. Performers are engaged in conscious, ritualized social gain through the purported exploitation of a neurophysiological potential. The latter process is essentially irrelevant, akin to sneezing or yawning. It is concluded that latah is a social construction of Western-trained universalist scientists. The concept of malingering and fraud in anthropology is critically discussed.

All Prime Contract Awards by State or Country, Place, and Contractor, FY 88. Part 6. (Alachua, Florida-Woodstock, Georgia).

DTIC Science & Technology

1988-01-01

9W P.- 1 1 (000 1-4-4 1 1-44-- 4. -4 -4 -4 --- 4 4-4-4 -4 ~-4--4 -4-4 "-4 N-4,𔃾 4-4 -4 F- I MOLA (0 I IWNNN m WNCNiC.JNC’J .. NൌN" m"N C𔃾 I(OLA( W 4...4 -4 -41-4 -4-4 -4 c -4 -4 c - A- 4- 4- l’- I MOLA (0 I JN NN N NN N 0N N NNl’,N MN 0N MN"NNN it IC00In(0 -4. -1-4-4-4_4--4-4 -4 ~~~-4 ’-4-4-4 -4 .l...toNNNNNCJ C1 MU (N C 0 0 (0 4N 0 0 I MOLA (0 1-4 -4 -4 -4 -4-4 -4 -4 -4-4-4 -4 4 -4--1 -4 -4-4 14 4 -4444- --fI4--4 o I (00A4 I -00000 ’-0 -000000000000 ’-0

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 85. Part 16 (Pilot Electric Co - Reyex Corporation).

DTIC Science & Technology

1985-01-01

1. - > m 4 1, - I.- i ILI NIB 10O- *W 440 J -4 41 0 Me 0- 0 a0-0j 0-4 1’-1 M- to mI v 0) 0. U 0 0. 3 -4 0 -4 3-) cl 04)14)0 I cc m41 04N 000 .4 04 . 4...0 4 00-C4 4" -N 0 4) 004 ’-4 0 404 (04N 04 NI 0 n0 cacao 0In 0 041 0 In 0 00 000-1 >00 -iN 0000 vot, I Goc )I O- n 0< 000 0C O OCIC 0 0 *~ I0. 4𔃺...W-4C’ w6-- de 0( I 4 0) 0- 0-4 CL-4 04L" 04 00 -4 CL 4 (5 C N44 C 4 4 4 4026 I --= I I 204 *L I If I -402 02) M n .1 n an .-- 4 mn a n Inlf InLnnman

All Prime Contract Awards by State or Country, Place, and Contractor, FY 88. Part 15. (Ada, Oklahoma-Youngwood, Pennsylvania)

DTIC Science & Technology

1988-01-01

1 aI 3 h C 4dl e eN e el c Ne( 0 ZZ mm CI (00 z I10000 I 04" IC N N NN 0 " NNNNN r- NN NN . -4 C04N C, -4-4 CN4 C- "N -4 U001- I "N NNNNNe4 .. . N...0 I 00coo00000 -(4 0 00 00 0 1 en 0 Il 000000 m r- r. - w00 00 0000 00 00 0000 01- -I󈧄 -. 00 0000 0000 cc I.oo 0 I 000000 80 00 00 o0 o0 00 0 z0 00...4co -C W 41 000 I’- -4C( P NNr 00 en ) N N UI) CL 1 030 r- I C)tc’n" (0 mm0’ WW C CN (D -4 4t IA r- 4 N bsJI )0r- 1 1 -4 NC’) -4 -4 N -4 I 𔃺)01 I I

All Prime Contract Awards by State or Country, Place and Contractor. Part 8. (Anderson, Indiana-Westwego, Louisiana)

DTIC Science & Technology

1989-01-01

I000 11 -4-4.-4 -4 -14 -4 01 -I (0 .4 N N1 1- I(MOO II r- CO (00 0 9 110(0 Coc N- co-) I MM 0ooo w If 1. 103M It U/) II0 CD (0r-. 4) -01 4-4-- 4-4...0((0 I C.-4-4 c 1-4 - - c -4 C -4 -4-I-4.-1-4 .-- 4 -4I C-4 c-4-4-4-4 r--4 -4 Io I M 0U I" (00( 14 ONNc"NN O N ONNNNNNN O i rh "N N NN ON N - 1(0(0 l

Activation of dynamin I gene expression by Sp1 and Sp3 is required for neuronal differentiation of N1E-115 cells.

PubMed

Yoo, Jiyun; Jeong, Moon-Jin; Kwon, Byoung-Mog; Hur, Man-Wook; Park, Young-Mee; Han, Mi Young

2002-04-05

Dynamin I is a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin I gene expression is induced during neuronal differentiation. Our previous studies established that neuronal restriction of dynamin I gene expression is controlled by Sp1 and nuclear factor-kappaB-like element-1. Here, using a series of deletion constructs and site-directed mutation, we found that transcription of dynamin I gene during neuronal differentiation of N1E-115 cells is controlled primarily by the Sp1 element located between -13 to -4 bp of the dynamin I promoter. Gel shift analysis demonstrated that in addition to Sp1, Sp3 could interact with this Sp1 element. The requirement for Sp family transcription factors in dynamin I gene expression was confirmed by using mithramycin, an inhibitor of Sp1/Sp3 binding. Mithramycin repressed dynamin I gene expression and resulted in blocking of neuronal differentiation of N1E-115 cells. The localization of the dynamin I protein was also restricted in the peripheral region of the nucleus by the mithramycin treatment. Thus, all of our results suggest that induction of dynamin I gene expression during N1E-115 cell differentiation is modulated by Sp1/Sp3 interactions with the dynamin I promoter, and its expression is important for neuronal differentiation of the N1E-115 cells.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 85. Part 20 (Tokkey Uluslarararasi Naklejet - Video & Sealing Inc).

DTIC Science & Technology

1985-01-01

ON 0- -1r)- 04 N00O 1(0 1-4 -#.-44 nO P4I 4 N 04 0 4 -1-4C M’ 281 0 11. u. cc =ta0 ’ 4 m 1004 ANl.(( 0 -O -t3- 0 UN W 0( I ce I- .40 -4 -4 1-4 14 0000...000000 00 00 000 4- I IO NCVI 1 00 I J (SN - -l4 ICNCJ .. to I ZWI In I I xo.( -1i ouooooooooooooooooooooooooooooooooooooooooooooo W -04 0 to N N990= = ao...Y C)N A 0 -4 04 - 4 4- .4 0A l -00 , 4c (00 I gn S ) 01- 1-- U)-0cccn- 0n 40n N NN -4 N (INN C, in4Uan- z CD-q z zwi I (00j I C 0) -z -C’ NV 00ltet

A family of silver(I) complexes built with 2-sulfoterephthalic acid monosodium salt and different aminopyridine ligands: Syntheses, structures and properties

NASA Astrophysics Data System (ADS)

Zhang, Jie; Tan, Gai-Xiu; Liu, Bao-Lin; Dai, Yu-Bei; Xu, Na; Wen, Wei-Fen; Cao, Chong; Xiao, Hong-Ping

2017-05-01

Five Ag(I) coordination complexes, namely, [Ag6(2-stp)2(3-methyl-2-apy)3·H2O]n (1), [Ag3(2-stp)(4-methyl-2-apy)3]n (2), [Na2Ag18(2-stp)4(2-Hstp)4(5-methyl-2-apy)16 (H2O)4·11H2O]n (3), Ag3(2-stp)(6-methy-2-apy)4·H2O (4), and [Ag6(2-stp)2(6-methyl-2-apy)8(H2O)2·H2O]n (5) (2-NaH2stp = 2-sulfoterephthalic acid monosodium salt, 3-methyl-2-apy = 3-methyl-2-aminopyridine, 4-methyl-2-apy = 4-methyl-2-aminopyridine, 5-methyl-2-apy = 5-methyl-2-aminopyridine, 6-methyl-2-apy = 6-methyl-2-aminopyridine), have been synthesized and structurally characterized. Complexes 1 and 2 show two-dimensional network. In complex 3, the adjacent Ag10 units are bridged by 5-methyl-2-apy ligands to form a 2D infinite undulated sheet. Adjacent 2D sheets are linked by coordinative bonds between carboxylic oxygen atoms and Na(I) ions to form a 3D coordination polymer. Complex 4 is a 0-D discrete trinuclear molecule, and the self-complementary the Osbnd H⋯O and Nsbnd H⋯O hydrogen bonds incorporating hydrogen bond motifs extend these molecules into a 2D supramolecular framework. Compound 5 exhibits 1D-chain structure. However, complex 5 shows 3D supramolecular structure results from the linkage of neighboring layers through a rich hydrogen-bonding between uncoordinated sulfonates, amino groups and coordinated carboxylates. The thermogravimetric analyses and photoluminescence of the complexes were also investigated.

Conducting Layered Organic-inorganic Halides Containing <110>-Oriented Perovskite Sheets.

PubMed

Mitzi, D B; Wang, S; Feild, C A; Chess, C A; Guloy, A M

1995-03-10

Single crystals of the layered organic-inorganic perovskites, [NH(2)C(I=NH(2)](2)(CH(3)NH(3))m SnmI3m+2, were prepared by an aqueous solution growth technique. In contrast to the recently discovered family, (C(4)H(9)NH(3))(2)(CH(3)NH(3))n-1SnnI3n+1, which consists of (100)-terminated perovskite layers, structure determination reveals an unusual structural class with sets of m <110>-oriented CH(3)NH(3)SnI(3) perovskite sheets separated by iodoformamidinium cations. Whereas the m = 2 compound is semiconducting with a band gap of 0.33 +/- 0.05 electron volt, increasing m leads to more metallic character. The ability to control perovskite sheet orientation through the choice of organic cation demonstrates the flexibility provided by organic-inorganic perovskites and adds an important handle for tailoring and understanding lower dimensional transport in layered perovskites.

Vegetation Resources of Rocky Mountain Arsenal, Adams County, Colorado

DTIC Science & Technology

1989-10-01

BE I Verbesina encelioides Cow-pen Daisy AF N 1’anthium strumarium Cocklebur AF A-4 Native/ Family/Species Common Name Life Form2 Introduced 3... strumarium Cocklebur Compositae SEMI-SHRUBS OR HALF-SHRUBS Artemisia dracunculus Green Sage Compositae Artomisia frigida Fringed Sagewort Compositae SHRUBS...Speedwell, Scrophulariaceae Xanthlum strumarium Cocklebur Coupos itae SEMI-SHRUBS OR HALF-SHRUBS Artemisia trigida. Fringed Sagewort Compositae ,.a

Dollar Summary of Prime Contract Awards by State, County, Contractor, and Place, FY 85. Part 2 (Adams, Indiana - Yancey, North Carolina).

DTIC Science & Technology

1985-01-01

M 00 4 0 0 fn N&- 4 C4...I0 in 1- cm m 07) 00 toPP 0 1~c it -40. v;- .40 N04N,0 0 0 0 0 W:no - Wi0 a -0 I 4- wan f - 4 N0n0 00 4NaqN I. 00 - 1-a V24~ ONl N 0V I- tO I* 0 wa r... m 14 I 00. ira 4 I- 1 0 1 .4 .4 se o ev e wes0e N07s ess 0sees 0 I.- ZI 0 a a 3t I I ’* 4. r- : I I’" 0o. I Za NN 07an 070)0 0 070 0000000N0.4 . 0

All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 21. Aberdeen, Washington-Classified Location, Domestic.

DTIC Science & Technology

1987-01-01

iNC*NNNN N I N IN (D 0~0 Nr I CJ " l l 1 1 N NN NN N * NNN NN NI NI Nl 001 I 0) 1 cl N N"N " C14 ciC4 0 1(4NIN 1 (NN NN N N IN COM 1 00 0 0 -1 000...000 I W IA I.- : COm -IN ML )0 4 n0- 1 - A10 ( N N M0 -0M n 00 44-4-4 M U) () 04 V(C)-CF JN00N)(’J4 4-4- - 4 Z M 0 0 0 0-4 0 -4 4 00 C 0 0 0-4 4 N0-4 0...0 V 0 - 004mI. I CoW00 < 0- I C O- COOOI - COLn 4 COA CO - CO C~O CO CO C)O4- COM - *I WOO< 40 -W 04 1W 4C 1W 1W -A -W 1W Z 04 MW 0 Q4 4 ., 4 0 44 1A

Familial Kleine-Levin Syndrome: A Specific Entity?

PubMed

Nguyen, Quang Tuan Remy; Groos, Elisabeth; Leclair-Visonneau, Laurène; Monaca-Charley, Christelle; Rico, Tom; Farber, Neal; Mignot, Emmanuel; Arnulf, Isabelle

2016-08-01

Kleine-Levin syndrome (KLS) is a rare, mostly sporadic disorder, characterized by intermittent episodes of hypersomnia plus cognitive and behavior disorders. Although its cause is unknown, multiplex families have been described. We contrasted the clinical and biological features of familial versus sporadic KLS. Two samples of patients with KLS from the United States and France (n = 260) were studied using clinical interviews and human leukocyte antigen (HLA) genotyping. A multiplex family contained two or more first- or second-degree affected relatives (familial cases). Twenty-one patients from 10 multiplex families (siblings: n = 12, including two pairs of monozygotic twins; parent-child: n = 4; cousins: n = 2; uncle-nephews: n = 3) and 239 patients with sporadic KLS were identified, yielding to 4% multiplex families and 8% familial cases. The simplex and multiplex families did not differ for autoimmune, neurological, and psychiatric disorders. Age, sex ratio, ethnicity, HLA typing, karyotyping, disease course, frequency, and duration of KLS episodes did not differ between groups. Episodes were less frequent in familial versus sporadic KLS (2.3 ± 1.8/y versus 3.8 ± 3.7/y, P = 0.004). Menses triggered more frequently KLS onset in the nine girls with familial KLS (relative risk, RR = 4.12, P = 0.03), but not subsequent episodes. Familial cases had less disinhibited speech (RR = 3.44, P = 0.049), less combined hypophagia/hyperphagia (RR = 4.38, P = 0.006), more abrupt termination of episodes (RR = 1.45, P = 0.04) and less postepisode insomnia (RR = 2.16, P = 0.008). There was similar HLA DQB1 distribution in familial versus sporadic cases and no abnormal karyotypes. Familial KLS is mostly present in the same generation, and is clinically similar to but slightly less severe than sporadic KLS. © 2016 Associated Professional Sleep Societies, LLC.

Elaboration and characterization of a free standing LiSICON membrane for aqueous lithium-air battery

NASA Astrophysics Data System (ADS)

Puech, Laurent; Cantau, Christophe; Vinatier, Philippe; Toussaint, Gwenaëlle; Stevens, Philippe

2012-09-01

In order to develop a LISICON separator for an aqueous lithium-air battery, a thin membrane was prepared by a tape-casting of a Li1.3Al0.3Ti1.7 (PO4)3-AlPO4 based slip followed by a sintering step. By optimizing the grain sizes, the slip composition and the sintering treatment, the mechanical properties were improved and the membrane was reduced to a thickness of down to 40 μm. As a result, the ionic resistance is relatively low, around 38 Ω for a 55 μm membrane of 1 cm2. One side of the membrane was coated with a lithium oxynitrured phosphorous (LiPON) thin film to prevent lithium metal attack. Lithium metal was electrochemically deposited on the LiPON surface from a saturated aqueous solution of LiOH. However, the ionic resistance of the LiPON film, around 67 Ω for a 1.2 μm film of 1 cm2, still causes an important ohmic loss contribution which limits the power performance of a lithium-air battery.

All Prime Contract Awards by State or Country, Place, and Contractor. Part 9 (Annville, Kentucky-Crofton, Maryland)

DTIC Science & Technology

1990-01-01

4.44c V c- U CU4 0 1.- (A 0.0 a* .W - 0. i- -4 C10t- (D I M 6 l UN W 0 >. GN C4 i ae ad )-4N0C, D,0 P. f6 MŔ R~ = 1- (0 00 .8 (A Q 0 0 Zococ3- 00cv I...In 0 P.- CM -4 0 -4 ’I- U u I 000 Go I -16 OC) f6 ’ -4 0A 0 CN - Ll.UC I oo r WNI 00 0 16060 I toN 4: N f 0 L I. I OP.- U -4 -. 4.4 -4 .4.4 .- 46. 4...00 "M M 0i 201(f 1 E00 -4 N)x 0 0 0 Q 0x- 0 0 F6 . Co C4- NI- al 2 0 Wi U) ~ ~ 1. C.) ai a 1 I0 04 N U)N-mN-NN -. 0-4- 1- 4 1.( 4-4 4 (Y00 0 ) -e4 n N

Lipid peroxidation biomarkers in adolescents with or at high-risk for bipolar disorder.

PubMed

Scola, Gustavo; McNamara, Robert K; Croarkin, Paul E; Leffler, Jarrod M; Cullen, Kathryn R; Geske, Jennifer R; Biernacka, Joanna M; Frye, Mark A; DelBello, Melissa P; Andreazza, Ana C

2016-03-01

Prior work suggests that adult bipolar disorder (BD) is associated with increased oxidative stress and inflammation. This exploratory study examined markers of lipid and protein oxidation and inflammation in adolescents with and at varying risk for BD type I (BD-I). Blood was obtained from four groups of adolescents (9-20 years of age): (1) healthy comparison subjects with no personal or family history of psychiatric disorders (n=13), (2) subjects with no psychiatric diagnosis and at least one parent with BD-I ('high-risk', n=15), (3) subjects with at least one parent with BD-I and a diagnosis of depressive disorder not-otherwise-specified ('ultra-high-risk', n=20), and (4) first-episode patients exhibiting mixed or manic symptoms that received a diagnosis of BD-I (n=16). Plasma levels of lipid peroxidation (LPH, 4-HNE, 8-ISO), protein carbonyl, and inflammation (IL-1α-β, IL-6, IL-10, IFNγ, TNFα) were assessed using analysis of variance and covariance models. LPH was lower in adolescents with fully syndromal BD than controls, while LPH levels in the at-risk groups were between healthy controls and fully syndromal BD. Post-hoc analysis showed a non-significant increase in the (4-HNE+8-ISO)/LPH ratio suggesting a potential conversion of LPH into late-stage markers of lipid peroxidation. There were no significant differences among protein carbonyl content and inflammatory markers. In adolescents, fully syndromal BD is associated with significant reductions in LPH levels, and LPH levels decrease along the spectrum of risk for BD-I. Quantifying lipid peroxidation in longitudinal studies may help clarify the role of LPH in BD risk progression. Copyright © 2015 Elsevier B.V. All rights reserved.

Cultural Resources Survey of Smithville Lake, Missouri. Volume 1: Archeology

DTIC Science & Technology

1977-11-01

relationships of these families 99 4J C at U 00 o <u o o 43 u »J n o PÖ i-l JB H ^ «4-1 ^ O 3 n en <y U-l CO O 00 efl... HH MH m 4H MH ɜH m m IH MH <*H <W •W W M-l CO to oi co co CD m st CO o o o o o oo CM CM st CO CM IN st • f...cd •H CO CO • <u • • 00 0 0) CO • •u R XI X! 4-1 4J •H -H XI oi c 4J >-3 cd c) o 14H MH 01 R ß -H HH X! •H o o cd cd XI

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 17. (Singer Company, The-Syscon Corporation)

DTIC Science & Technology

1989-01-01

00 0) if Im to, HZ -4 fr 0 00 00 Iin0(-0) C>0 D0 0 - -4 1 1- I ea( 0C0 tint’f-00C> 10 0 Lr 0.) a. 00 on : I enc - It OO O N - N ( N N ~ 0 4 4 - N N - 0...C< ml I1 (-1C( c iI 1 -4 -4- - - eNC LN ( INS I .N N . 1,N jXN~N L-.-4 .- 1N C -. of 0-4Nɘ � ( L’O -00 t CO m 0 O 00 000 m4 COO 0( if IM C...00 c 0> 0a 0I 0 C>0 0 GOq’ it en-4N( -4 o o o- o0 oa W-a oo o oo 0 4)Q C IMP e-4i ca I- L N cl NNNN1 "N LC’ N OXeJ C1, ENc , N cN 16- L- ) to Of Im en-4

Identifying Military and Combat-Specific Risk Factors for Child Adjustment: Comparing High and Low Risk Military Families and Civilian Families

DTIC Science & Technology

2013-06-01

families (N=200) and civilian dual parent families (N=200). The objectives of this study are to: 1) identify and measure developmentally salient skills ...identify and measure developmentally salient skills that are indicators of current adaptation among preschool and early childhood boys and girls of... Skill Achievement i. Preschool Aged children 1. Self regulation: the 36-item Early Childhood Behavior Questionnaire – Very Short Form (CBQ-VSF

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 1. (102 Construction, Inc.-American National Management)

DTIC Science & Technology

1989-01-01

KTN M4 I- M MN 0 .1-4 4 r-ON- a N r-r- 00 ’- 400 N- cma 0C00 N PN- (0 *mm" 44)- I nI 40 4 , , , 1 -4 w - 1-4 m N -4 N~ Moo0 U, 0)IIO0 I ( -4 N C1) -40...0 -4 If 40M( II, 0. 0t 4 M 00m 0.-40-4 a- 0 C-4"ONNN00 - 400 4T Nl oil I 05( 1 C, 0 -. 1i 0D -4C >C -40 -4-4--4 -4 -4- 40 -40C>-J! 0-1 0 0>~I 51 I...0 40 If 0 10 M I I 0> InaO< < 4n 444U U’)nU"UU oU 40 CON ( D0a C>Q 0- r0 ?- NUn 11 < CO-4 II CI >0 0 - - 400 - "-4 - 4-0 4 0 >-0) O)N t I 41110 -4 If

Geographic List of Prime Contract Awards. Oct 1992-Sep 1993. FY 1993. (Air Force Academy, Colorado-Washington, DC). Part 3

DTIC Science & Technology

1994-03-01

0 0 a a. aL OC I ccN( N NjN W4~)4l~4v)4 (4(Vf) qq nn %V) 4(4f) V) t4)m (W aN in(0cl N r bPP % Pr. .r% 4ý a. PI% N.r.r Pr%I. P.. r... ar..a r, .. P a...J4 It) 0 Ut00 .1 IfI WOW04 160.4 .4 -4.4 .4 .4C4n -4.-4.4 (n -4 N-4 N P, Ln W Lfl40q 4OD Y 0) -0. 0 M Cn6 6 100400 11. O ffa I W6 co0 o it >- iI U I

All Prime Contract Awards by State or Country, Place and Contractor. Part 4. (San Buenaventura, California-Ventura, California)

DTIC Science & Technology

1989-01-01

40 .4M %-4- -4h Ch4 InN0NN N .- 4 .W 00-o4< -s~ ti4N 40 N -,4- -.4.4"N -f 4000000a -4N -4 -- 4N < I 1 Go4N 61 U0000 (AN *0)d 40 40- IRSN ...4NCI -4 4-4I.I -40 -4-I4 -I-I .- 4-4-4 -1-4 4.4 -NN II K M -40,4 K n $13 IN 00>->-)-* fie IV> 4 La f4>)-* PON IRSN mu(00* IGO. KEIO-4o oz2 02 0222Z

Community Noise Exposure Resulting from Aircraft Operations. Volume 5. Acoustic Data on Air Force Propeller Aircraft

DTIC Science & Technology

1978-02-01

6 .- 6 a . I a- S 0 I I C3 uI nm0 14 * N N 𔃾 nInA󈧒 C3 f6 - ~ S C3S00 0c h )4 a1 SnI S i LU 14 0 I0 w 1 .- 4 1- pejz I C SW4 - #N0Wa*% 0( IW -W~ x...m #a CAC3 * DtoKIDft4 lp 3 I f6 . lt-C3 lat *0- IL 0 19 9 9 999 **9 U% .49 9999 I (A o3 0-1.1 N N .80* us-Ia. , NF0In m UN O.4 " 0.2 4% 1 I 1 WI "i I4...G OPIA0 0* N.4C " DI 0.3, 0=6s (A 6 4 6 4 .4 *L 7 I I f6 1 0 CLx 2 W N M9 0% *ON 40 MNca.4t C3 GON 00’p.*!fU ON N I o x11 j eS .4 4 I 6& ILI’N I L5

Reduced gas seepages in serpentinized peridotite complexes: Evidences for multiple origins of the H2-CH4-N2 gas mixtures

NASA Astrophysics Data System (ADS)

Deville, E.; Vacquand, C.; Beaumont, V.; Francois, G.; Sissmann, O.; Pillot, D.; Arcilla, C. A.; Prinzhofer, A.

2017-12-01

A comparative study of reduced gas seepages associated to serpentinized ultrabasic rocks was conducted in the ophiolitic complexes of Oman, the Philippines, Turkey and New Caledonia. This study is based on analyzes of the gas chemical composition, noble gases contents, and stable isotopes of carbon, hydrogen and nitrogen. These gas seepages are mostly made of mixtures of three main components which are H2, CH4 and N2 in various proportions. The relative contents of the three main gas components show 4 distinct families of gas mixtures (H2-rich, N2-rich, N2-H2-CH4 and H2-CH4). These families are interpreted as reflecting different zones of gas generation within or below the ophiolitic complexes. In the H2-rich family associated noble gases display signatures close to the value of air. In addition to the atmospheric component, mantle and crustal contributions are present in the N2-rich, N2-H2-CH4 and H2-CH4 families. H2-bearing gases are either associated to ultra-basic (pH 10-12) spring waters or they seep directly in fracture systems from the ophiolitic rocks. In ophiolitic contexts, ultrabasic rocks provide an adequate environment with available Fe2+ and high pH conditions that favor H2 production. CH4 is produced either directly by reaction of dissolved CO2 with basic-ultrabasic rocks during the serpentinization process or in a second step by H2-CO2 interaction. H2 is present in the gas when no more carbon is available in the system to generate CH4 (conditions of strong carbon restriction). The N2-rich family is associated with relatively high contents of crustal 4He. In this family N2 is interpreted as issued mainly from sediments located below the ophiolitic units.

Stable divalent germanium, tin and lead amino(ether)-phenolate monomeric complexes: structural features, inclusion heterobimetallic complexes, and ROP catalysis.

PubMed

Wang, Lingfang; Roşca, Sorin-Claudiu; Poirier, Valentin; Sinbandhit, Sourisak; Dorcet, Vincent; Roisnel, Thierry; Carpentier, Jean-François; Sarazin, Yann

2014-03-21

Stable germanium(II) and lead(II) amido complexes {LO(i)}M(N(SiMe3)2) (M = Ge(II), Pb(II)) bearing amino(ether)phenolate ligands are readily available using the proteo-ligands {LO(i)}H of general formula 2-CH2NR2-4,6-tBu2-C6H2OH (i = 1, NR2 = N((CH2)2OCH3)2; i = 2, NR2 = NEt2; i = 3, NR2 = aza-15-crown-5) and M(N(SiMe3)2)2 precursors. The molecular structures of these germylenes and plumbylenes, as well as those of {LO(3)}GeCl, {LO(3)}SnCl and of the congeneric {LO(4)}Sn(II)(N(SiMe3)2) where NR2 = aza-12-crown-4, have been determined crystallographically. All complexes are monomeric, with 3-coordinate metal centres. The phenolate systematically acts as a N^O(phenolate) bidentate ligand, with no interactions between the metal and the O(side-arm) atoms in these cases (for {LO(1)}(-), {LO(3)}(-) and {LO(4)}(-)) where they could potentially arise. For each family, the lone pair of electrons essentially features ns(2) character, and there is little, if any, hybridization of the valence orbitals. Heterobimetallic complexes {LO(3)}M(N(SiMe3)2)·LiOTf, where the Li(+) cation sits inside the tethered crown-ether, were prepared by reaction of {LO(3)}M(N(SiMe3)2) and LiOTf (M = Ge(II), Sn(II)). The inclusion of Li(+) (featuring a close contact with the triflate anion) in the macrocycle bears no influence on the coordination sphere of the divalent tetrel element. In association with iPrOH, the amido germylenes, stannylenes and plumbylenes catalyse the controlled polymerisation of L- and racemic lactide. The activity increases linearly according to Ge(II) ≪ Sn(II) ≪ Pb(II). The simple germylenes generate very sluggish catalysts, but the activity is significantly boosted if the heterobimetallic complex {LO(3)}Ge(N(SiMe3)2)·LiOTf is used instead. On the other hand, with 10-25 equiv. of iPrOH, the plumbylenes afford highly active binary catalysts, converting 1000 or 5000 equiv. of monomer at 60 °C within 3 or 45 min, respectively, in a controlled fashion.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 88. Part 3. (Bakers Constr. Co., Inc.-Burns Lumber Co., Inc.)

DTIC Science & Technology

1988-01-01

00000 00000000 uI Wo m0 1 00000000004. "m0.-.4- 4~. - I WOO0 I *-4-4--4--4* -4O r- () )Mcc4-44 cc W CO ww wwww www w I4 L 0 -1 1 r- , fr r- - - w , f- r...34 NNNC0 N N -4 00 w 0 N4 4c1 Woe) I (0W -i - WWW V t’- N In 0 In (0 In CL I WOMI 1 -𔃾 4 M𔄁CI) M C C’ n (0 M" -4 (𔄁 .0 ’WON 0 444444 44400! 4 o cn...10)00 CN go* O N 00N 00(0 00(0 V N 00W 001- 0’)0 f00 10000t 0N WWW OWY -4 e-4 -4W -4 m 0 0 l D-4 -0 C-10 ON 4WC r-’I i-xm I I m c .-0 .-4 N -4/ rn

All Prime Contract Awards by State or Country, Place, and Contractor, FY 88. Part 19. (Abington, Virginia - Yorktown, Virginia)

DTIC Science & Technology

1988-01-01

00( z Q I 40(1 I (0 C-1 (0 N-Np- -4 0) 11- (D(D (D LA Ln Ln m (n (70 -4 0) (D 044ɘ (1 10)N( 4AC 000 -4N- -.0 LADO C OOOONNNNOOOO q*0C0 400 W440(1Or...I4CD-4 0 I - ENC -4N CI I -INr~ .- ENNN "’-4NN4C1 -- ENC -4 1N cl -EN .4NC4 N 4 40M0O) I >NC >NN4 >NC’ >NNN S >NN, >N" >NC >NC >N4C > 4N I40000004 0 00 0...LI-00COW0 W I mocli IZOOOOOOOOOOOOUWIAOOO eNc - oco - ɘ wooocw - 0 CL I MON l0OOOOOOOOOOOmz u)O - -u -4 L) CL C) wzzzzmu I MO-4 1 1-1 < < 1-1 < < z

All Prime Contract Awards by State or Country, Place and Contractor. Part 7. (Aiea, Hawaii-Zion, Illinois)

DTIC Science & Technology

1989-01-01

000 oao 0000 ’ 0 10 1 a I 0> I 01300011N 1 in 21 14-4 4140 (D 0 0 N1 -4 U) C1) (n N W I U)rK>U 11 0-4 -44-4-4 q-4 0-4-4-4 0.4 -4-4 0.-I 44O N N N in...4 if4-00 )r )(O c 00 -4 00 NO 0M 04 ,P-4 (4M (07) (0 r- on 1,-4 144(I0M4 if4-4 ."(-10 t VI = 141 Mx 00 Ni 20 4441 00 M 1 V 00 N 00 < 4140 ) I(0-4l if 4...00 4 44 It -0440 M 0 100 0 100 I0 (10 000000 140000 4140 MOO w- SI - x M fit0 mI M0 -40 1-400 -4 I -0 .n Z-400 0 0 -40 󈧬 045 I4’ (04 II .-4N 0 c

Dollar Summary of Prime Contract Awards by Contractor, State or Country, and Place, FY 85. Part 5 (Seaward Construction - Zytron Corporation).

DTIC Science & Technology

1985-01-01

4𔃺 00 1.C~ f6 Ln N a do00 0 wa n a L 00 43n 0) -ci e4 N1 C14 00 a ~. OD.4 , c I LL. z :i% -4- j i - 0) r -- - 0 I 0 0 00 N oc 0)) co 0)01 00 0 0 ~ J...0 1 1. F6 O. II -F- . I- I .- I I. .C. . . . . . . . . "A6%4 % UU- W4 w CL8 8:0 I 4 I Wt C V 08 I 8 I I e Cl dc m I ) I I Coc (D 0 C nI 4 ( a (4t 4...tLI 0 Z am a - o -4 I I,- - a4 C 0 C-4- acca a O-c 0)( C -. Na( an1 c . -.4 N. Nm ca ’. -. %--ca4-4 0 - a E I Ua an .0- 4 C r- Na C)G I-0C 0 0 0’ 0 ) 0

What Comes Beyond the Standard Models, Proceedings to the 9th Workshop held in Bled, Slovenia.

NASA Astrophysics Data System (ADS)

Mankoc Borstnik, Norma; Nielsen, Holger Bech; Froggatt, Colin D.; Lukman, Dragan

2006-12-01

Contents: 1. Child Universes in the Laboratory (S. Ansoldi and E.I. Guendelman) 2. Relation between Finestructure Constants at the Planck Scale from Multiple Point Principle (D.L. Bennett, L.V. Laperashvili and H.B. Nielsen) 3. On the Origin of Families of Fermions and Their Mass Matrices -- Approximate Analyses of Properties of Four Families Within Approach Unifying Spins and Charges (M. Breskvar, D. Lukman and N.S. Mankoc Borstnik) 4. Cosmoparticle Physics: Cross-disciplinary Study of Physics Beyond the Standard Model (M.Yu. Khlopov) 5. Discussion Section on 4th Generation (M.Yu. Khlopov) 6. Involution Requirement on a Boundary Makes Massless Fermions Compactified on a Finite Flat Disk Mass Protected (N.S. Mankoc Borstnik and H.B. Nielsen) 7. How Can Group Theory be Generalized so Perhaps Providing Further Information About Our Universe? (R. Mirman) 8. Future Dependent Initial Conditions from Imaginary Part in Lagrangian (H.B. Nielsen and M. Ninomiya) 9. Coupling Self-tuning to Critical Lines From Highly Compact Extra Dimensions (K. Petrov)

Prime Contract Awards by State or Country, Place and Contractor. Part 4 (Salinas, California - Lompoc Valley, California), FY1991

DTIC Science & Technology

1991-01-01

1 L)if I M4’) 100 < of ICO 1a" 0..( crI of ) " i X I- H 011 WCN I(A z EfmE 1 3 I4 o 0f mIi I mcON I’ ~0L4C0L0O)0AIC)0’N𔃾LN-C.4)-4CCLC)4)00~C ofI z...00n Inn~~U~f Gn)fUU U o LU L) NLL a 00 4N N m oo---444444--.4- COO- - -4 4 4 4- - - - 0.o0 04o- 4M 100 NO moo0 0 j IX N11- 10000c N 4 0000 4 -ON -0)000...2j O il to N I ciI- $._ I 1-4_ J ZN 100 N13 U 11 wo x IN4 0 Na (0, 21 - 4co()0r na >c4r-I 0- o ni 7 .- - 4ɘ . D 0 0 $_r 044 81 CN NfC)0 Y o - * 4r 0

CPD -20 1123 (Albus 1) Is a Bright He-B Subdwarf

NASA Astrophysics Data System (ADS)

Vennes, Stéphane; Kawka, Adéla; Smith, J. Allyn

2007-10-01

Based on photometric and astrometric data it has been proposed that Albus 1 (also known as CPD -20 1123) might be a hot white dwarf similar to G191-B2B or, alternatively, a hot subdwarf. We obtained a series of optical spectra showing that CPD -20 1123 is a bright He-B subdwarf. We analyzed the H I Balmer and He I line spectra and measured Teff = 19,800 +/- 400 K, logg=4.55+/-0.10, and logN(He)/N(H)=0.15+/-0.15. This peculiar object belongs to a family of evolved helium-rich stars that may be the products of double-degenerate mergers, or, alternatively, the products of post horizontal- or giant-branch evolution.

Two solvable problems of planar geometrical optics.

PubMed

Borghero, Francesco; Bozis, George

2006-12-01

In the framework of geometrical optics we consider a two-dimensional transparent inhomogeneous isotropic medium (dispersive or not). We show that (i) for any family belonging to a certain class of planar monoparametric families of monochromatic light rays given in the form f(x,y)=c of any definite color and satisfying a differential condition, all the refractive index profiles n=n(x,y) allowing for the creation of the given family can be found analytically (inverse problem) and that (ii) for any member of a class of two-dimensional refractive index profiles n=n(x,y) satisfying a differential condition, all the compatible families of light rays can be found analytically (direct problem). We present appropriate examples.

All Prime Contract Awards by State or Country, Place and Contractor. Part 6. (Alachua, Florida-Winder, Georgia)

DTIC Science & Technology

1989-01-01

0-4 N :: fIilNN N N N NNN N N N- N N N NQ’ C.-1-4 48 2 2 2 2 z z2 22 M 2 2 2 Zof 0-40 It 104 0 44 4 0 N 4L 0) M 8 It 000 filico!I 00 !d x zaW < K 011...1)2-4 -4 < tuN V)M-4 fl.11) ..- 42 1, (0N MM tcOC’)U)00-4mU)2-0 0) 00 0) i1 inC-U)N0) .4 It I N <Cj ifm-4U)’Lnw)(04) ON -44 4t00 0-4-4 -4-4 - 0 0...8217N N 4U-4.-4-4 tUN (UO) M 4-4.--4I-4-4 -4 dUO 0101 UN0I 0-4N00 11.0 0 -4 00000 --4 0 -hC A 0 _4(. 4 (A 000/00(000000() u ( , -0 ., r-at I M -4 4 C f

A Test program to Determine the Feasibility of Installing Utility Meters in Military Family Housing, Developing Energy Ceilings, and Operating a Penalty Billing System for Occupants who Overconsume Energy. Volume I.

DTIC Science & Technology

1980-03-01

replacement of existing breaker boxes with preassembled meter sockets and disconnect switches. At Fort Eustis, the electric meters were also provided...entered a common box were found to be installed on the wrong side. The latter problem was a result of improper wiring during construction which had not...o ’t i thi v 4k mh i Ae n1 r, ow it k ’ips As Ii~’ !I rt ~’ o~w t hs e aIo , 1kwh ’liuensl Mos ’ ilowwI kmit’ one .%%lok isnh,’s no ______Alt_10 _00

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 6. (Dobbins Lou, Inc.-Fahey Machinery Co., Inc.)

DTIC Science & Technology

1989-01-01

0 (-4N4- H0 -.4C.) -. 4 a) () -40) -4 0 ) w 0N %- M C(00) z to IG0 -Iff1 ._40 N I 0 -4 4 5 0 ) L0)) 0 .-. 01-4~ . 0 .4NCJ0) 1-1-4 -4-4 0 )’ ao I -4N... 0 -4 00 0 -n O Olo(c x( c -d0 41r- -C4 N00 to II0 0 - I N N C1,1 0 r -4 -4 r-U 1 0 ... .J0)00N MLI-I0-41 1 00 o0 30- 30 30)mv0v-, 0 a o 5 Qo oN 0114/81 M...100000000000 4I <_1B4.4 110 0D 0n 0n 0 0 00 ofl W I Owl>u if ON 0C Or0N ON" 0 -I

Siblings' Power and Influence in Polyadic Family Conflict during Early Childhood

ERIC Educational Resources Information Center

Della Porta, Sandra; Howe, Nina

2017-01-01

This study examined sibling behavior during polyadic family conflicts (involving three or more family members) by identifying operational conflict elements (i.e., roles, topic), power strategies, effective influence of power, and social domain argumentation. Polyadic conflict sequences (n = 210) were identified in 35/39 families with two siblings…

Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Jacobus Pharmaceutical Co. Inc. - Level 6 Systems Inc.). Part 11

DTIC Science & Technology

1994-03-01

LL:9 131 -a31 nC I COO.-4 1c4) 000000000000 heGo0(0 -. 100 JO L)O u10 (/.2 - ) _j u 0) I U CIO00-a 111 flnUn ( ( n A A n n(n w 0 (0( 0 4<< 4 04< 04411 0...0 0 0000 .- ~ 0 0 0-440 : N1 coo0 If 0-•I .,o®H. II OOf N HO 4444 4 444 4 OH 100 H N N LA.I 04c1I 100LH 0 0 0 0 0 0 0 0 00 0 C N 1 0 01wL’ULI 0. (n 1...0 03 I • (• I 0 0 00 0 0 00 000000 0 0 0 0 II U..-4(I) 100 00 00le 00 00 000 0000000 00 00 00 00 If I u -4N II N N NN N N NN N INNNN N N N N II I 0

All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 16. Aberdeen, North Carolina-Youngstown Municipal, Ohio.

DTIC Science & Technology

1987-01-01

04 0 01 0 00 00 00 ’ .4 C4 C* 4 -4- 4 C44--4 N NCV - 4 .4 3 Ca a* 0 3)I O 0 30 30 0 - OO O 310 30 30 03 1-lu 13 04 0 0 0 00< OC < -C) 0 C 0 Ct...c)- )c v ncv )c)c 4C)c)( )mmc N N N 4 - N Nan 1 0 -4 1 -4 4-4-4 -4-4 -4 4-4-4- 4. -- 4-4 - 4 -4 - -4 4 -4 -4 N"N N" " N NNN -4I I 0-.0 a to N1 Nl m1...Nl N1 N N Web U00 0 0) 00-i 00000000-I 0 0 0 0 0 0-I 0 o 0_)10 0 004C 000000004 0 0 0 0 0 04C 0 100000 0 0 001 - 000000001- 0 0a 0 0 0 01- 0 I 0 0 0

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1987. Part 8. General Fire Extinguisher Del.-Hawthorne of Missouri, Incorporated.

DTIC Science & Technology

1987-01-01

0-4 .4n~(D r-4.4.4.--00-4N -4O4N4N Q 103 (n 0 l 0 I I toN (n oC 00 0 000000c000 o 0000 00 4i 0000000000000000000000000 00000000 -0 1I00007mo 00...Ij 0 0 00 0000 0 o 7Ŕ CA 00O Io L) ’- I- 4n (oWI W rh - 4 -4 - "oi Io DO Io .- D 01 4NCA 00 01 n0) 0) 0) z0 NI -4 coo N I3 OO I y)W( -4 -0 -4 4 4 0 0...4 00 00 C’) C) 0D 0-4 000 In 0 0 0- 00030 00000 蓐 M40) 1 Co W- Inco COW(D’ CO I CIDr CO r-Cr--- 0 pC-- pD (-pW r--r.-ow0 -4) ow ow 0000 COCOCO

New optimal asymmetric quantum codes constructed from constacyclic codes

NASA Astrophysics Data System (ADS)

Xu, Gen; Li, Ruihu; Guo, Luobin; Lü, Liangdong

2017-02-01

In this paper, we propose the construction of asymmetric quantum codes from two families of constacyclic codes over finite field 𝔽q2 of code length n, where for the first family, q is an odd prime power with the form 4t + 1 (t ≥ 1 is integer) or 4t - 1 (t ≥ 2 is integer) and n1 = q2+1 2; for the second family, q is an odd prime power with the form 10t + 3 or 10t + 7 (t ≥ 0 is integer) and n2 = q2+1 5. As a result, families of new asymmetric quantum codes [[n,k,dz/dx

M-X Environmental Technical Report. Socioeconomic Impact Estimates for Millard County, Utah. Detailed Tables.

DTIC Science & Technology

1980-12-22

rv a N NOm r 0. I N e V. 0 o’lN N’) Nvci 4 10 d DNV ’C N M’ CL1 NON .1 N C ’i C’ N’C a,(’N 090 MOO .(~0 ~ N Ird 0 V 0 -14 v 0 .0 m 0 N 4M N I C- lt V W...73 , 043 0 43 4 43 7 - o 0 03 4 z. 4C 3 4) 33 04- - . 7- 7 4 0 77 Q3 00 3E0 -~ I I’ ’ ’iwL a. -. - .4 4. I- L, 2.7 Uz; .3 z 7 2 Zj C) Ia 4 - I .. C I...u 0 mCulu 0 Cun 0 ,u’ m 0 Il -’D Cu N. Cu 0. C- C’ rv 0 .N u m. Cu r.0 M )0. 0 L W Io (n - -’Cuu ( VM -J -. I m -Im I 0 NO t ND 0..00 0 NOM 0 m n O 0

Acquisition, Contracting/Manufacturing Job Series 0801, 0896, 1102, 1103, 1105, 1106, 1150, 1910

DTIC Science & Technology

1992-06-01

S TA TES 7AAIJR FORCE 0 OLPH AFS OCC UPA TIONA L SUR VEY REPOR T ELECT SEP2 8199 , A JOB SERIES 0801, 0896... a , ’ SM ad 140 ’ a 0 z z z U 4. 10 .4 -4 𔃺 .m L %T𔃺. .4 I 0 m 3w 44. Z ca l Ns 𔃺.40 0’ I I I s I I I 1 z 0 : ac SM z. %n a ol N IN N ’p 4 41 1 4 44...WA .4 I.-U. 0 Z 40 1- z ~ .4 .4 I @ 0 S I .4 I S I I I S N N I S iN .J N 00 cc " C0 LAI0U 0 0 z 0 z SM c 0 at.L z 04 u 0 0 zCC

All Prime Contract Awards by State or Country, Place, and Contractor. Part 5 (Vineburg, California-Wyoming, Delaware)

DTIC Science & Technology

1990-01-01

4 a:: wi :t mo 400 N erntiofl0o~Nco cf),4In m in N It N O0) I I C) q N! 1 )-11uIto00 N qt 1- 0 0 0) 15.1 C: c 40 N Me o- -4 CV) 00 I M100 00 Nf 04 NCV ...00.-4 1 61 4 t wt it 4 q**- 0 nCV ) ..I)0)00 I- M m0Y) m0I00m0MCV00m000Y00mIn00Y00000m000000000) IL.4 (-4 NNINNNNNNNNN 00 00000C004- q- .. 4-4- 4 - 44...4N N ൰CV N N 4 .40 8&.NC40000 NCV )(’ am 000 N> in 24 Z.C’%> a EI*0 woo E E E E E 9 III - I Coc 1140 -i at 0 0 -mN 06* 00 Is40 10 V V 1L a. UI *6

A Systematic Approach to Achieving High Performance Hybrid Lighting Phosphors with Excellent Thermal- and Photostability

DOE PAGES

Fang, Yang; Liu, Wei; Teat, Simon J.; ...

2016-12-07

We have designed and synthesized a family of high-performance inorganic-organic hybrid phosphor materials composed of extended and robust networks of one-, two- and three-dimensions. Following a bottom-up solution-based synthetic approach, these structures are constructed by connecting highly emissive Cu 4I 4 cubic clusters via carefully selected ligands that form strong Cu-N bonds. They emit intensive yellow-orange light with high luminescence quantum efficiency, coupled with large Stokes shift which greatly reduces self-absorption. They also demonstrate exceptionally high framework- and photo-stability, comparable to those of commercial phosphors. The high stabilities are the result of significantly enhanced Cu-N bonds, as confirmed by themore » DFT binding energy and electron density calculations. Possible emission mechanisms are analyzed based on the results of theoretical calculations and optical experiments. Two-component white phosphors obtained by blending blue and yellow emitters reach an internal quantum yield (IQY) as high as 82% and correlated color temperature (CCT) as low as 2534 K. The performance level of this sub-family exceeds all other types of Cu-I based hybrid systems. The combined advantages make them excellent candidates as alternative rare-earth element (REE) free phosphors for possible use in energy-efficient lighting devices.« less

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 88. Part 19. (Synertech Associates, Inc.-Tucker Equipment Co., Inc.)

DTIC Science & Technology

1988-01-01

1-r. -wOq* o 0 v-* vvqtq "V so 400960 I- WO La U," 5 U),U 1, 0 wwo Uft www owm flm w woqa : C0 NNO N "NN N - 0 000WIWo m’ V 0 U, -4-4- mmmmm0 -4 1-4...Om 0 000000000iini 50-4 I N N4 N -44-4 -4 -4-4 -4 N -4 -4 NN4 Nl NN N NN 50000 I -4 -4 -4 - -4 -4 -4 -4 -4 4-4 -4 4 -f -4 44444- 50000 5 -4 N 4 N -4 -4...PP=P 100.4 1 0000 00 ,00-0 1 0000 00 I00w I -4-4-4-4 .4- 500-t 1 444- .4.4 500(4 5 N N -4 N C4NN 4 N (4N N N NNNNC1 -4.4 N4 NINNNNNNNN SO)ON 5 CC4 NNN

Alpha List of Prime Contract Awards. Oct 91 - Sep 92. FY 92. (Thayer Electric Service Inc - Universal Applicators Inc)

DTIC Science & Technology

1993-01-01

NOi 0 00 0 in0 00 0 0 43 SOONj N- I-) I*6-1 0 m I.- N O S I 00 ()= 1-1 (n) I-" N z O 0 2r de 00 U) Ge 0 z 0 NE 1 ONC Nw 0 ma 00 0 ZU. 1.- 0 140 < N 66...Zn Zo) X-4 Zo Z 7-4 20n Z(.V 0 ’U I 00-4 a cc 4 Woom cc ca 0 Woo de In GO GC. zC5 c-4 Cie o ac IA. 0 - 1 100-04 H . Col wmoo W-4 W I- I- W 0 WOU. 2...I de H-I WO.- II 004 N00 )0 nt -c 4i n& ni 4c e ntn nc 4r tq iw )- &q t- 1t n 0OO0eMM 0.wmiw - cc Nc - 44 nL - 1- 4- 4- 4- - 4- 404 0 0- t0 0 C4 0r In

All Prime Contract Awards by State or Country, Place, and Contractor, FY 85. Part 15 (Altus, Oklahoma - Zelienople, Pennsylvania).

DTIC Science & Technology

1985-01-01

Iso CM I m -4 0N 4 MNNNNNN"N-4-4 aN ION w O 40 UNNN liN 40.4 4 OR 60 4 14 .-4 -4 ..4 -4f -4 I-’ 1 0 0 0 0 0 0 0 0 0 -i aJC 0 4 1 4 i q--4-4--4 -- 4...4 azo azo ixN 0 .0 woo 000 0zo 01( C’) -I .4 0i~o x-0 0 4 N - ((0 04 03(0 ()I 1 -0 -4 0~00 x -0 0 04 " .(A 0 04 0.0 .4 0’( 4C I m i 41013 ə 3tr irn

Dollar Summary of Federal Supply Classification and Service Category by Company. FY 87. Part 3. Q504-R505.

DTIC Science & Technology

1987-01-01

I 0) (N 4 ) mc4 (N (N -C140 t 4 u ( N -4 C𔃾 -4 in * L4 I V) 0’ 10-LI V) In V / ) V )U 0: L LJ u jw ’ ’ WI w wLi LL ~ ’ OIL )u )UC Uu L C- 0- C WI...AVAILABILITY OF ABSTRACT 121. ABSTRACT SECURITY CLASSIFICATION 0 UNCLASSIFIED/UNLIMITED El SAME AS RPT. E -DTIC USERS I 22a. NAME OF RESPONSIBLE INDIVIDUAL...c 4 nI I , w- 0 0 -4 N’ m F,- m~ m0 m0 m v t-- (0 v m0 m0 w0 - i4l m w -a I I LI (( I C14 ( i F- ( i -4 -.4 (N4

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells

PubMed Central

Vaeth, Martin; Schliesser, Ulrike; Müller, Gerd; Reissig, Sonja; Satoh, Kazuki; Tuettenberg, Andrea; Jonuleit, Helmut; Waisman, Ari; Müller, Martin R.; Serfling, Edgar; Sawitzki, Birgit S.; Berberich-Siebelt, Friederike

2012-01-01

Several lines of evidence suggest nuclear factor of activated T-cells (NFAT) to control regulatory T cells: thymus-derived naturally occurring regulatory T cells (nTreg) depend on calcium signals, the Foxp3 gene harbors several NFAT binding sites, and the Foxp3 (Fork head box P3) protein interacts with NFAT. Therefore, we investigated the impact of NFAT on Foxp3 expression. Indeed, the generation of peripherally induced Treg (iTreg) by TGF-β was highly dependent on NFAT expression because the ability of CD4+ T cells to differentiate into iTreg diminished markedly with the number of NFAT family members missing. It can be concluded that the expression of Foxp3 in TGF-β–induced iTreg depends on the threshold value of NFAT rather than on an individual member present. This is specific for iTreg development, because frequency of nTreg remained unaltered in mice lacking NFAT1, NFAT2, or NFAT4 alone or in combination. Different from expectation, however, the function of both nTreg and iTreg was independent on robust NFAT levels, reflected by less nuclear NFAT in nTreg and iTreg. Accordingly, absence of one or two NFAT members did not alter suppressor activity in vitro or during colitis and transplantation in vivo. This scenario emphasizes an inhibition of high NFAT activity as treatment for autoimmune diseases and in transplantation, selectively targeting the proinflammatory conventional T cells, while keeping Treg functional. PMID:22991461

Transducer Workshop (15th), Held in Cocoa Beach, Florida on June 20-22, 1989

DTIC Science & Technology

1989-06-01

PROjECT TASK WORK UNITELEMENT NO NO NO ACCESS;ON NO 11 TITLE (Include Security Classification) FIFTEENTH TRANSDUCER WORKSHOP (UNCLASSIFIED) 12 ...8217 -17 - N~G m1 N𔃾 C𔃾L Nr - -4 -4 m in aO aO as I ’ (,40 m’ I𔃺 m C c l0 a (n I O1 E4 -1.- C’l- 1~ 4 ~ - 4 (𔃾 -4 N -4 N-- (4 0. 0011 4 I 0 U u $4C 4) 4...senso’ ! C n I c T . v p Thrill s Fro, mu, b e i ’rv e~ in te f i ld1 us i nr : er ;’nFiree’ I t h andI he In o e’ v pe ra t ed’ PT RON I? T - L i r

Peer Ratings: Scoring Strategy Development and Reliability Demonstration on Air Force Basic Trainees

DTIC Science & Technology

1980-09-01

C5 co 00. I~ O O 0D,~Oo w0%0%v%0 ooD o to tD ~o % % D otvi i..I.0. N P.% . N.NP IV o0 ;% o0 4 0*0c 20. 6.z w) m"w t w ma +i f f f osaV 0Vc 4 Gc 44Nq u o...IN -~ 0 v , ( 6 I ft CS alo K1 0 .4-4 .4 -4N fIN I NNN JNN NN N N N iN N N10% JAJ N CJN N NN IJ Wb S -t m.mŘ 00 0 NPN o em O m w ti .S 0...444 .4 .4...no o n o m1 " o 4 ~ a. T onl W* W)in I CID.,N JM M M *. A tD ~ 0~@ ~ ~ ~ s. co44%fJ N U M *S4 IIELAA~ N .*C C#SG’ U~l.. a 0j 0A I~MAI l~Al AlMt M MM M

Identification and Functional Characterisation of Novel Glucokinase Mutations Causing Maturity-Onset Diabetes of the Young in Slovakia

PubMed Central

Valentínová, Lucia; Beer, Nicola L.; Staník, Juraj; Tribble, Nicholas D.; van de Bunt, Martijn; Hučková, Miroslava; Barrett, Amy; Klimeš, Iwar; Gašperíková, Daniela; Gloyn, Anna L.

2012-01-01

Heterozygous glucokinase (GCK) mutations cause a subtype of maturity-onset diabetes of the young (GCK-MODY). Over 600 GCK mutations have been reported of which ∼65% are missense. In many cases co-segregation has not been established and despite the importance of functional studies in ascribing pathogenicity for missense variants these have only been performed for <10% of mutations. The aim of this study was to determine the minimum prevalence of GCK-MODY amongst diabetic subjects in Slovakia by sequencing GCK in 100 Slovakian probands with a phenotype consistent with GCK-MODY and to explore the pathogenicity of identified variants through family and functional studies. Twenty-two mutations were identified in 36 families (17 missense) of which 7 (I110N, V200A, N204D, G258R, F419S, c.580-2A>C, c.1113–1114delGC) were novel. Parental DNA was available for 22 probands (covering 14/22 mutations) and co-segregation established in all cases. Bioinformatic analysis predicted all missense mutations to be damaging. Nine (I110N, V200A, N204D, G223S, G258R, F419S, V244G, L315H, I436N) mutations were functionally evaluated. Basic kinetic analysis explained pathogenicity for 7 mutants which showed reduced glucokinase activity with relative activity indices (RAI) between 0.6 to <0.001 compared to wild-type GCK (1.0). For the remaining 2 mutants additional molecular mechanisms were investigated. Differences in glucokinase regulatory protein (GKRP) –mediated-inhibition of GCK were observed for both L315H & I436N when compared to wild type (IC50 14.6±0.1 mM & 20.3±1.6 mM vs.13.3±0.1 mM respectively [p<0.03]). Protein instability as assessed by thermal lability studies demonstrated that both L315H and I436N show marked thermal instability compared to wild-type GCK (RAI at 55°C 8.8±0.8% & 3.1±0.4% vs. 42.5±3.9% respectively [p<0.001]). The minimum prevalence of GCK-MODY amongst Slovakian patients with diabetes was 0.03%. In conclusion, we have identified 22 GCK mutations in 36 Slovakian probands and demonstrate that combining family, bioinformatic and functional studies can aid the interpretation of variants identified by molecular diagnostic screening. PMID:22493702

Dollar Summary of Prime Contract Awards by State, Place and Contractor, FY 85. Part 1 (Alexandria, Alabama - Yorkville, Illinois.

DTIC Science & Technology

1985-01-01

m - zago zi 9zs 0 m U)l 4c140 0 "< z( . 40 21 I z)-0 "o 0 W 0 >W~ zl "I 00 (04It06 lN t04 01 U (i C0...IU I. In 4c * NO a 05 ’ 44 E - I I A 0 CO I q~o c N M inI5V F z I. I. . .- 01 I- 0. 0 -1Nc4 .4 CL C N- (ogo - C- z I.- w R a. A0 w . z 0 0-I" 14.$A I9...a.n GoCV)t-0 a C1 m n m ’ I. CVI CV in OD) N C) 4 0 ~ ~~ a . r a O aca 40 Z au ’ FJ.. *.4hmN 0- I : N 1 04 1 I. *c’ a-J a 00C)r P oI 4 a . 9 -4 .a a

Structural and electronic properties of armchair graphene nanoribbons under uniaxial strain

NASA Astrophysics Data System (ADS)

Qu, Li-Hua; Zhang, Jian-Min; Xu, Ke-Wei; Ji, Vincent

2014-02-01

We theoretically investigate the structures, relative stabilities and electronic properties of the armchair graphene nanoribbons (AGNRs) under uniaxial strain via first-principles calculations. The results show that, although each bond length decreases (increases) with increasing compression (tension) strain especially for the axial bonds a1, a4 and a7, the ribbon geometrical width d increases (decreases) with increasing compression (tension) strain due to the rotation of the zigzag bonds a2, a3, a5 and a6. For each nanoribbon, as expected, the lowest average energy corresponds to the unstrained state and the larger contract (elongate) deformation corresponds to the higher average energy. At a certain strain, the average energy increases with decreasing the ribbon width n. The average energy increases quadratically with the absolute value of the uniaxial strain, showing an elastic behavior. The dependence of the band gap on the strain is sensitive to the ribbon width n which can be classified into three distinct families n=3I, 3I+1 and 3I+2, where I is an integer. The ribbon width leads to oscillatory band gaps due to quantum confinement effect.

A Review of Parametric Oscillators and Mixers and an Evaluation of Materials for 2 - 6 micrometer Applications

DTIC Science & Technology

1974-07-01

44 ’a N -1 - ’ O𔃺 0 IU U O hl af f T o 8 N0 N 0!I .II . I N tD . N - -- N" N c00 0 ’~ 0 t4 .W 1 A 0 0 40 Q, Z.- 4 cc I n In m-" In w) ’n 41 N z0...Id 36 - 12 (Ref 39) Ref. 39,40 Id 14 I Id36 td Jsine (Type I) _____1 36__ _ _ _ _ __ _ _ _ _ _ _ 36 AgGaSe 2 T2m Negative Id 36 = 3 (Ref 41) Ref...4~~C’.-4.4 ’-tCl -40 (4C’J’J.l00 .-4.I.- 00 H. 04MrIrI"c) ý - 2- td Ln oo N o 0 NC 4’.OC4 V- N-: - C4 ~s ~~ NV.%D a 0t- 4 - n &nIfVl r cN O 1t N

Geographic List of Prime Contract Awards. Oct 91 - Sep 92. FY92. (Fort Hood Texas - Northfield Vermont)

DTIC Science & Technology

1993-01-01

00N00LALAm00)LA0 -- n, o-, nc4-- n( )m-zTI o-ir -- * 0)CIO 1C) -- i-s a) CI W N 1wo jini nI-I 0 o o01 o ,w 4-1t in WL L L L 0 00 0 0 A 0 01"C4 0 ’ ~ 0C14r...411 N ,N 1`4 NJ I Q -4-4 to >-.-- zzzzzzz z zz ZZ ZZ> >>--> - Uf C41I 0-40 11 au Mə <<- JINI 4- (04 4N014INN Uf 00(n o U n (inl ý4 - I4-4- 4 -4 i...N Is 1(000o atoz z z z z z z z zz z motto00 It 7) 00 0U)..VN(to-4 N l (a0 000 0 0 In01C* an 0 Ga I(00 Gao If 0)C0an.0(0 In O0NC 0 0 0 -*MM’ N o A IC

Dollar Summary of Prime Contract Awards by State, County, Contractor and Place. Part 2 (Alachua-Menominee)

DTIC Science & Technology

1990-01-01

0c -4 -40)4- * L Iit m * 40 404 CD to I 4 0)0m (a 04) a~ CV -1*c 𔃾 I4 C)II tun I nco -4 0V) C) m 0 01~~~~~e CO I ON N000 N0l I2I4 N 0 CO In 40) - 0 0...WO a.I-1W z o -0z zw1- " WWM4- oo mx04C’)4Ua Ŕ(1~f 0004-NBaN’a004’N004-4-0Z flC’ Wa K- ) II= 0 I N a N(𔃻P- zAw ~ 0 -aQfl4-4N 0 a -00(’)0t7- N ofa a0

All Prime Contract Awards by State or Country, Place, and Contractor, FY 88. Part 2. (Acampo, California-Loma Linda, California).

DTIC Science & Technology

1988-01-01

0 0 I 000(1 I -fN.-40)31(00 r- 00 M 00 In) 347 NO (0 In n ) U 4I0m0om I N 0 140ONN C, 0-4 0 -4 N4 0 NNO4O~ 0 00 0 I30m0om I qct o 04NŔ) 0) CON N1 C...C1400l400 -4 ce0 J-4Im o 0-4 If0U0UV000u 40 O0 l dx c c e c e ~ e d 0 x0 " -0 (DO(L -J I Mo-I I >-I-Ww(ccn~ nOWO 0 w AnD0o oo u w n0n Ln n ww , r- t- 00 w00

A Systematic Review of Family Meeting Tools in Palliative and Intensive Care Settings

PubMed Central

Singer, Adam E.; Ash, Tayla; Ochotorena, Claudia; Lorenz, Karl A.; Chong, Kelly; Shreve, Scott T.; Ahluwalia, Sangeeta C.

2015-01-01

Purpose Family meetings can be challenging, requiring a range of skills and participation. We sought to identify tools available to aid the conduct of family meetings in palliative, hospice, and intensive care unit settings. Methods We systematically reviewed PubMed for articles describing family meeting tools and abstracted information on tool type, usage, and content. Results We identified 16 articles containing 23 tools in 7 categories: meeting guide (n = 8), meeting planner (n = 5), documentation template (n = 4), meeting strategies (n = 2), decision aid/screener (n = 2), family checklist (n = 1), and training module (n = 1). We found considerable variation across tools in usage and content and a lack of tools supporting family engagement. Conclusion There is need to standardize family meeting tools and develop tools to help family members effectively engage in the process. PMID:26213225

A Systematic Review of Family Meeting Tools in Palliative and Intensive Care Settings.

PubMed

Singer, Adam E; Ash, Tayla; Ochotorena, Claudia; Lorenz, Karl A; Chong, Kelly; Shreve, Scott T; Ahluwalia, Sangeeta C

2016-09-01

Family meetings can be challenging, requiring a range of skills and participation. We sought to identify tools available to aid the conduct of family meetings in palliative, hospice, and intensive care unit settings. We systematically reviewed PubMed for articles describing family meeting tools and abstracted information on tool type, usage, and content. We identified 16 articles containing 23 tools in 7 categories: meeting guide (n = 8), meeting planner (n = 5), documentation template (n = 4), meeting strategies (n = 2), decision aid/screener (n = 2), family checklist (n = 1), and training module (n = 1). We found considerable variation across tools in usage and content and a lack of tools supporting family engagement. There is need to standardize family meeting tools and develop tools to help family members effectively engage in the process. © The Author(s) 2015.

All Prime Contract Awards by State or Country, Place and Contractor. Part 20. (Aberdeen, Washington, Riverton, Wyoming)

DTIC Science & Technology

1989-01-01

Operations and Reports REPORT NUMBER Arlington, VA 22202-4302 DIOR/ST 1 -89-PT- 20 9 . SPONSORIKIG/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSORING...NNNNNNNNNNNNNNNNNNNNNNNNNN’ L 0( O(N -4 - .-4 11 =W-II ’.. C -40 >C 00 0000 =1C>0 000000000 aC>C.a 0 0 000> . nIif If 0I LAI 10 it Inf- it < <<Z nI O : zzz zz zZZZZZ ZZ...4. 4 .- I - > -4 > -4.-I-4 > -4 > -4 > -4 > -4 >-4 001 ’, I ((0 : WI ON NNN N N 0404N OI I N NCJ a )NNN 47N a) O )N W N ON) " )NNi >1 03Ico < II 9 nL

Far-Field Acoustic Data for the Texas ASE, Inc. Hush-House. Supplement.

DTIC Science & Technology

1982-04-01

wJ t* = -W 0 0.0 cu x. C. m 4!T a. 1 1I IA r2 m0 r t S ’ (A WA w. ". .9 wL * . ac ti 40 I m. aL O 0.14 .) . w -4 En 1 4~~~ 0n an ~ .~( LL (AU. a.3W 0...I I I A (P8%48~t N0I f IS I I coI N m M V4 MO N MM M 6N I 1 0 1 0 .* . .. . . I N 1) %0JO e 10kainM rt w tSY (n0 En " I N W M V 0 4tF . I4 Ilg~g w r 1...A m~ommm at a-at t- * * I m* m a 5 1. tS go .W m 0A400. 0* eN d W) I 4 z 5 -?ZX5OGs II*PII. 1 0 5 OR I ’. Of . I of 50 I * V)A9Ct. 1;4 44944a so ~ ~ 1

Prime Contract Awards by State or Country, Place and Contractor. Part 17 (Clifton, Virginia - Greenland), FY1991

DTIC Science & Technology

1991-01-01

performing identifying major subjects in the report. the research , or credited with the content of the report. If editor or compiler, this should follow...000 n InanI nn i W0u n in O) i n i in n InfIn in U S ((04C U n Wf) W)infi in! l 1AlIl in an n in in in inin In In I U .. I (D IfD U 1 NN4 CNN N...34 .4 cc -4_ j_ -. 1 -. _0jN Kj 000 r44- -4 4- - NC0 ("IN~ P.P.P.P.P.I-4 00 jI -4 U. K (0 I cocaN KfC 00 0000000-4& 00 00 000 -ct00 0 0n R 00 K)0 00 sN

Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Food Services INc. - Greenbay Supply Co. Inc.). Part 8

DTIC Science & Technology

1994-03-01

C4 IaN I-INY "-I4..4.4.4 1 4 0 0 0 0 0 0 0 0 IL K m0 I 00.4 0 "-t W In x G 1-0000 i-10100 I-0 00 0 000n qoo ~ U 40 I in0.-4 It -I.. XINz dE £0 Zqt0 V0...14 W 0. I 004’ 1: ONO-40- -4 CU)00 --4 -. 4 0) .- NN 0 0) (flN0-- N-W4V .- 400-Nd0) 4-4- .4 N -4 471 14 I cacao 1O OH I to00No aI .as 411 1: 1 0W N...uI 1 00 0 a) " Z >.Z= 2C sZ >tZZ z Z 2C z CZ Z CZ z cacao o . go• Je 0 c 0 qto .19 Co M• $_ .o0 Su 0 I IŕO 0 00 0 ONO N 0 00 W ! "-C" (a a HI 1000

Work, family, support, and depression: employed mothers in Israel, Korea, and the United States.

PubMed

O'Brien, Karen M; Ganginis Del Pino, Heather V; Yoo, Sung-Kyung; Cinamon, Rachel Gali; Han, Young-Joo

2014-07-01

Our research revealed differences in work-family constructs for employed mothers in 3 countries, Israel (N = 105), Korea (N = 298), and the United States (N = 305). Although levels of work-family conflict were comparable, the Korean women had the lowest levels of work-family enrichment compared with the Israeli and American mothers. Moreover, Korean women reported the most depression and the least support from both spouses and employers. Spousal support mediated the relationship between work-family conflict and depression for employed mothers in Israel, Korea, and the United States. As hypothesized by conservation of resources theory (Hobfoll, 1989, 1998, 2001), threat of resource loss (operationalized as work-family conflict) was related to depression more strongly than was resource gain (i.e., work-family enrichment). PsycINFO Database Record (c) 2014 APA, all rights reserved.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 6 (Colson Equipment Inc-Delta Engineering Inc)

DTIC Science & Technology

1990-01-01

4NN cow -i =0 an 0 10 fta e ~ fw w w 0-4N a NaL00N0 nop-- N- Do 00) (0 00 (0 ft - 4. = 4N0 a Vtfttf. fftfftfttfVftfft v . ,C)e)mmmmV V)f ft co0 ft ft...4 i N CNNNN N * 0 Oft Kx 0C 0 0C 44 C -cc0 44 4C *ON W W 0 A 0C K U3-4 :oz 02 02 0-’- 0- 0)- 0- 02z 0) - 0---- 0)- K c) : M.f K fta ftI 0M 0 Mt 0 ft... FMD MIo 4 0c U010- L. to P I -- N-4 to 140 w Mc-I. .0-4- .- 4-II-a-4 ccI Co .-I -40 am U 0 I M0 Rr a 0 0 0n~n~ 000w4 n InnOf~n~ 00 00 0- M C C U I

All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 14. Adelphia, New Jersey-White Sands Missile Range, New Mexico.

DTIC Science & Technology

1987-01-01

N N N N N N N4 03100 9 0) 0 N000.J Nc 0 N0. N- 0 0... 0 N 0 0 cacao 010 0 00041 0 00-1 04 0 04- 0 041 0 0 i101001 0 0 0001- 0 004C 01- 0 01- 0 01- 0 0...hJ0000th 00 (I 0000000 9L I A004 I .4-4-el *-40 L) I in0 *.-44.4-eco L4.- " -0 M -eem-m4-e-4e-4- De ) ma~ *40) 0 *.m4 N 0001 CL 40 100 000O 0-00-0-0 x04...1-. Ln 4) 01 q 4 N de I l -*I 01 &1 ago 01 0 402 0 0 too1 up 4 4A ~ OA >. II U0 Z9 1’ 1 1o 0 0 30~~~ ~q 010. N 0. 1 (14- 1 (( 04 41N 01( 0 01( 3.4 0m

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1985. Part 5 (Columbia Asphalt & Gravel Inc - Dela Tek Inc).

DTIC Science & Technology

1985-01-01

40 40 4000 1 O- 4 00 000 0 C 40 40 ca c 1- Q 4- - In In In o - In 0 co l. 40 l N N 𔃺 C)3 0 0N In In IN N I N I 𔃺’ D coca In4 Of4 I 4 W 4 W 1 NWWI. 4...1( n r- PP, - P - - - )0 00 awl-I qt0( Coo 0- -I41-- <- M (0 " 00000000mm) C 00 000 om- -1-4I I.NOI1)1) W1 ’. * * (0 .17 0000 -CM 0.3 0C4C - Coala Ow... coca r-. 4.-U, M LA4( 44( 0I NY NN4 NNic N N ( C) N (0" M (0 04o -44 3 4( 4 44 44 4d -C 4 33 4 -4(0 K m( -4 43l CK00 0) 00 00 0 0 0 00 0 0U 0)co C I

Prime Contract Awards Alphabetically by Contractor, State or Country, and Place. Part 16 (South Dakota [State of], Brookings, South Dakota - Tekna, Mountain View, California), FY1991

DTIC Science & Technology

1991-01-01

4 - %-) N6- NN 4 .4 C.4 0 .4N Ho. up r-( r- N4 Nn NO. N N- NN M 040 H >.A WIx 0 -Cl 4c. q*j r- W W4 en H~C t-4OHI C00 C4 (D V 00 000~0 o CO a ccN H𔃺...I- I-- ə IW C-4 /) I-I. z I.- 2 z 2 Z z 3 IS I We-i if < 00 1-1 0 #-4 1-0 I- 1-4 0- < IS I Web Uo IP- I-- If M" ISO a a a 0 0 a 1-i ,0W UZ IS Z 2w 2...C4 C4 C4 Cj C-4 e4 C4 C4 C,4 cm ൌ (4 cli 04 " cli cm CS1 C4 e4 cm C14 c4cljcqclI"NNe4rqNN CIA CS1 C4 eq C14 C14 C4 C4 N C4 CSI eq C4 1 131 wix

All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 22. Antigua AN-Indonesia.

DTIC Science & Technology

1987-01-01

r. -4 N * I0 (4 0 0 (40 N ONO0 C,40 NN04O -4 Nl N4 N MM0C’ IN 0000 In W 0O0. ONLI LA 0) 0 0 N 0 OhP Z I (4M1 0-4 00 0 -40 -40 00 𔃾 𔃾 0 -4 0 I V w4 a...30 40 afl *00n ’ 𔃺am mem *0nI 3*( 0’(((((( C󈧄 W 03 W W to(0 Wu-M c 00 ininn tom IM IO co I I t- M0 l0 0 -4 0 𔃺 0) IoN ONCYNINNNN 0-4-4-4 ONNN N

Dollar Summary of Prime Contract Awards over $25,000 by Contractor, State or Country, and Place. Part 1 (102 Construction Inc, Oklahoma City, Oklahoma -- Bay Cities Refuse Co, Sunnyvale AFS, California), FY1991

DTIC Science & Technology

1991-01-01

L I-m 0d 0 td 4 10.1-4 4L o ) 0-40 # 2 I XI i( iC c u :W ( W .1 1- Ie ix W0- cc -4- (00 0 0-0 CO I E 00N0 00((0 UU) 0 0 0 3 00 o *zz a txa...43 td 00 0N -4 t - ) CZ IS WI - IL < (M I. 1.- (0 (0 z -- 0 0N f 1 Ii Iu -4 --4z L 0 I CI D- = 0- x I- c ow ( I- I I e 0 I.I. w 0 1Q4 0 0- I0.- C )C...LU 05 01t- 0 00 -4-4 o~c cc I- I c P:M 0 4e 1 C1 cl-4 -4 44 N I c 00 td E(0 c0 10 00 w 4 4- N N < 4-0 -4-4 - 0 c I 44 - 9 -I M IA- I 00 E >I (,C. 14

A novel method of optimizing patient- and family-centered care in the ICU.

PubMed

Allen, Steven R; Pascual, Jose; Martin, Niels; Reilly, Patrick; Luckianow, Gina; Datner, Elizabeth; Davis, Kimberly A; Kaplan, Lewis J

2017-03-01

Patient- and family-centered care permeates critical care where there are often multiple teams involved in management. A method of facilitating information sharing to support shared decision making is essential in appropriately rendering care.This study sought to determine whether incorporating family members on rounds in the intensive care unit (ICU) improves patient and family knowledge and whether doing so improves team time management and satisfaction with the process. A nonrandomized comparative before-and-after trial of incorporating family members on rounds (July to December 2009 vs January to July 2010) in a single quarternary center's surgical ICU assessed (1) family members' knowledge, (2) nurse's and physician's satisfaction with the intervention, (3) frequency and timing of family meetings, and (4) physician's workflow. Intensive care unit demographics and use were similar between time frames. Presurvey (n = 412 family members; 49 nurses) and postsurvey (n = 427 family members; 47 nurses) were coupled with presurvey (n = 5) and postsurvey (n = 6) physicians' informal feedback. Family knowledge of the clinical course and plans increased from 146 (35.4%) of 412 to 374 (87.6%) of 427 (p < 0.0001). Nurses were nearly uniformly satisfied with planned family interaction on rounds (presurvey: 9/49 [18.4%] vs postsurvey: 46/47 [97.9%]; p < 0.0001). Family meetings per week outside of rounds substantially decreased from a mean of 5.3 ± 2.7 to 0.3 ± 0.9; p < 0.001). Goals of therapy including end-of-life care became an element frequently discussed on rounds with families (presurvey: 9.4% ± 4.7% vs postsurvey: 82.5% ± 14.8%; p < 0.0001). One intensivist was dissatisfied with the process. Incorporating family members on rounds in the ICU improves communication and satisfaction and shifts the team's time away from family communication events outside of rounds, condensing most of those activities within the rounding structure. Critical care nurses and intensivists were principally satisfied with the process. Therapeutic, level III.

Official Guard and Reserve Manpower Strengths and Statistics. Fiscal Year 1982 Summary

DTIC Science & Technology

1982-01-01

DI ’a D~ U.. O 14( 11) f.IF) U0 0F)Cn D.4- F- aIaDP iDC n l 4. wlU a’ ý w fN 0 n C K) T) -P" F CW a l ) Nn w) (’o F-4 o( C...CIn OW~I ;0 - 4MT 4i on 0. H WI l - 0 PI4 .4C) .4i 4 4 N W’)NNP) t .’ P2-iP I flD N 4I LL. (F L0 Di0C )t Di YW 0 4 O %W nll)ýP ON sý4 )"C I LP ,I N 6...8217 V) 4K 1L 6; - N In 4ý v4 w4 O0a vC l 4440 4K 6K1 I DI 4’ tflLi 4M 49 ii 4. ;c 4i 0 W 4 M. wIL In 0q x~ 4i w. cc 4 4j 64 6 w0 ~ 0’Ir 0 .4’ m 4 V 4

A New Class of SINEs with snRNA Gene-Derived Heads

PubMed Central

Kojima, Kenji K.

2015-01-01

Eukaryotic genomes are colonized by various transposons including short interspersed elements (SINEs). The 5′ region (head) of the majority of SINEs is derived from one of the three types of RNA genes—7SL RNA, transfer RNA (tRNA), or 5S ribosomal RNA (rRNA)—and the internal promoter inside the head promotes the transcription of the entire SINEs. Here I report a new group of SINEs whose heads originate from either the U1 or U2 small nuclear RNA gene. These SINEs, named SINEU, are distributed among crocodilians and classified into three families. The structures of the SINEU-1 subfamilies indicate the recurrent addition of a U1- or U2-derived sequence onto the 5′ end of SINEU-1 elements. SINEU-1 and SINEU-3 are ancient and shared among alligators, crocodiles, and gharials, while SINEU-2 is absent in the alligator genome. SINEU-2 is the only SINE family that was active after the split of crocodiles and gharials. All SINEU families, especially SINEU-3, are preferentially inserted into a family of Mariner DNA transposon, Mariner-N4_AMi. A group of Tx1 non-long terminal repeat retrotransposons designated Tx1-Mar also show target preference for Mariner-N4_AMi, indicating that SINEU was mobilized by Tx1-Mar. PMID:26019167

A New Class of SINEs with snRNA Gene-Derived Heads.

PubMed

Kojima, Kenji K

2015-05-27

Eukaryotic genomes are colonized by various transposons including short interspersed elements (SINEs). The 5' region (head) of the majority of SINEs is derived from one of the three types of RNA genes--7SL RNA, transfer RNA (tRNA), or 5S ribosomal RNA (rRNA)--and the internal promoter inside the head promotes the transcription of the entire SINEs. Here I report a new group of SINEs whose heads originate from either the U1 or U2 small nuclear RNA gene. These SINEs, named SINEU, are distributed among crocodilians and classified into three families. The structures of the SINEU-1 subfamilies indicate the recurrent addition of a U1- or U2-derived sequence onto the 5' end of SINEU-1 elements. SINEU-1 and SINEU-3 are ancient and shared among alligators, crocodiles, and gharials, while SINEU-2 is absent in the alligator genome. SINEU-2 is the only SINE family that was active after the split of crocodiles and gharials. All SINEU families, especially SINEU-3, are preferentially inserted into a family of Mariner DNA transposon, Mariner-N4_AMi. A group of Tx1 non-long terminal repeat retrotransposons designated Tx1-Mar also show target preference for Mariner-N4_AMi, indicating that SINEU was mobilized by Tx1-Mar. © The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Reduced dimensionality tailored HN(C)N experiments for facile backbone resonance assignment of proteins through unambiguous identification of sequential HSQC peaks

NASA Astrophysics Data System (ADS)

Kumar, Dinesh

2013-12-01

Two novel reduced dimensionality (RD) tailored HN(C)N [S.C. Panchal, N.S. Bhavesh, R.V. Hosur, Improved 3D triple resonance experiments, HNN and HN(C)N, for HN and 15N sequential correlations in (13C, 15N) labeled proteins: application to unfolded proteins, J. Biomol. NMR 20 (2001) 135-147] experiments are proposed to facilitate the backbone resonance assignment of proteins both in terms of its accuracy and speed. These experiments - referred here as (4,3)D-hNCOcaNH and (4,3)D-hNcoCANH - exploit the linear combination of backbone 15N and 13C‧/13Cα chemical shifts simultaneously to achieve higher peak dispersion and randomness along their respective F1 dimensions. Simply, this has been achieved by modulating the backbone 15N(i) chemical shifts with that of 13C‧ (i - 1)/13Cα (i - 1) spins following the established reduced dimensionality NMR approach [T. Szyperski, D.C. Yeh, D.K. Sukumaran, H.N. Moseley, G.T. Montelione, Reduced-dimensionality NMR spectroscopy for high-throughput protein resonance assignment, Proc. Natl. Acad. Sci. USA 99 (2002) 8009-8014]. Though the modification is simple it has resulted an ingenious improvement of HN(C)N both in terms of peak dispersion and easiness of establishing the sequential connectivities. The increased dispersion along F1 dimension solves two purposes here: (i) resolves the ambiguities arising because of degenerate 15N chemical shifts and (ii) reduces the signal overlap in F2(15N)-F3(1H) planes (an important requisite in HN(C)N based assignment protocol for facile and unambiguous identification of sequentially connected HSQC peaks). The performance of both these experiments and the assignment protocol has been demonstrated using bovine apo Calbindin-d9k (75 aa) and urea denatured UNC60B (a 152 amino acid ADF/cofilin family protein of Caenorhabditis elegans), as representatives of folded and unfolded protein systems, respectively.

Prime Contract Awards by State or Country, Place and Contractor. Part 18 (Germany - Yugoslavia), FY1991

DTIC Science & Technology

1991-01-01

04 IN C> enC o 0 0f0 C. 0 40 el 40 0000ufen>.0l u 0 -M4N0)I N 0 44 N > 40 0 00 C> 0 CD 4 -OOC>OC N M-INO- N 0 0 .-eflO eneOC a 0D C> No 0 -o404-441...0 1 04 D N40 U0 00000000000 >C10 0 00 0 000000 0 U I GO-* U -4M-4000C 40 0 0 0 00. -4 > 0C𔃺C m- I~ I ~ c) U 4 C1) c) M’c 40 0000cn-4 V) c enC m C...m’).4 If 11 I00)r N Z -4 -4-4 -4N040 C, eNc -40 N k "c’) 0 N .o"N-I -4C0N10 -4 W N I (0 If 0 0) ()0)() 0 In 0) 0) -411 (0(0(0 soLAn 00 N0() 00 C’J-4

Geographic List of Prime Contract Awards. Oct 1992-Sep 1993. FY 1993. (Alpine, Utah-Pulaski, Virginia). Part 12

DTIC Science & Technology

1994-03-01

0in0 Aco00) o Y 1)-0 ONmN(0iOn 00 001Y)0 00C 00c 00 cca00 C. 11 0 IC (0 V 4JM-% II C4O(4 M00 0 MMN,-4.V-4 -- JCM 4JNCQ + 4-(n 4j tv1 +) (47 +3(4M + 347 ...0.440 0 0 0 0 N I mo wN 0 L) x- 4 lON I WOW 0... 4- u - U l ON I coI- 0I 0 Ný NOWO a .j 0 cc 0 4K lOO mo 4i I-- U. I-- 511 0oot- I. 4 1- I6- Ci I floON N

All Prime Contract Awards by State or Country, Place and Contractor. Part 5. (Adobe, Colorado-Washington, DC)

DTIC Science & Technology

1989-01-01

U000000004000 0 4.001000000000 I- ft I COW Is f00 L00CO LOC Looooooooooo L0 O O OO O O 0 mf :4 Ir rr r or- ft fCl) I4 r’.4. I-- P. I.-4 -4 P P4’ P P0... LOC L o L&-oca L00 L00 L0 L0 LO O1- N1 ).3 - a00 N V 04 04 0-4 04444l- 044q 0-*- 04t 0-0 04W 0 I-N C. 3004 Na e L O C Q L LO LO0 . L0 NI3004 Nt Ŕ = mo... LOC La ) La)C N 1 a-4N< Nt 0-4 0 4 4 .4 I 040 0-4 *to 0-4 000( 00 0a) Nt 1 0- A4c N " N -j- 4d.q- 4- 41- -I-I "IN -to Ř.4 -4 -4111 -4-4 -4N 0 1 Q0

Interlevel Correlations of Temperature and Density, Surface to 60 KM

DTIC Science & Technology

1980-05-14

N 4 W ON . .4 4. 40 N 2NW N N 0.04’ 44 0N4 I N no In CTnO 0y a. N N~ Wq I N 4 M ANA. 4N 4 4 N *f~ 0 I No0 N N won N N I 1 00A N 2 U 0 N In W 04* ON m...40. d 5- 14𔃺 ’ 4’C 110*0 44.4102 . itm 4m, 0 0 4wID oU MI .0 a’n ’. UI tao M u . o0’ Nj It%U’ .4n N 0 1. ow 4LJ N.41 .4 a MMM _j 0 D4 Z P2 0 w0 w

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1987. Part 5. Conti Corporation-Donley-Bundy & Associates.

DTIC Science & Technology

1987-01-01

8217 I ( 0 0 . C . -. - (0 (0 c.-.C.C. U- C.) 0 *Y 0 040 Ni N0 .0 0000 0 t- 0 0 (0(0(000 (1 I C.) In 00 Go0 (n m LflOo -4-4 W0 en 0 0 c c r’)) NN CV C4 4...8217-. 0 00 60 00 z~- 00 m - i n 6 -400 c -4 -4 -4-4-4-4 ɜ -4c 04 N-NN-NI N-N-N-N- I6 oo I UOO Ow 0 A WCUA0Zc A r c L < W WC AW0( 60 6 N EN 0 00u0 60 < : 0...w0 = 4 - I 7 - = v N u>N Wn (O WA M M 40 WM< 0of 0ci 0 0 0)N U00 0L) 4Y 0 0 knn - -so w0I M < 6 0-14 -1N ON N O 4NNN< 10~4 ɘɜ EN " N NN N 00NNN0

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 88. Part 6. (Data-Easton Machine Corporation)

DTIC Science & Technology

1988-01-01

City, State, and ZIP Code) 7b. ADDRESS (City, State, and ZIP Code) Arlington, VA 22202-4302 8a. NAME OF FUNDING/SPONSORING 8b. OFFICE SYMBOL 9 ...to u 0 300- I cInr 1- IL71 O0 0 1= I v V- EU 10001- I 0 M fa V CE0 1 CI o 100 3(- 9 -4 3-. 3t-4 -4 CA4 4 -4 W-4 - .. 4’.-I-4 00.f.4 4-I 0-I I...I 00003’ 44-.4.44 r4 r0) 1- 00 U44a ( 9 WLAC’) o .,’r-r-- r-3=-.-r 00 r- i-. I’- 1-’o- 411Wa0(1 I M ( t1nC n S 0M U n . (n(C’In (1n n ( 0nL C) 0 M1 M

Geographic List of Prime Contract Awards. Oct 91 - Sep 92. FY92. (San Juan California - Yale New Haven Conn)

DTIC Science & Technology

1993-01-01

414 -4-- - - 4 4 4 4 N Ř I-. I 00(0 if w0 Coto (0(0(0(000woo 0D0(((000(((0000((000(c(DW-I (0 M of4 0001 0 acca " 00 0 0 0 0 00 0 0 00 0 0 0 0 00 - 0...w l" I"r---0 InNC- (00C -.1~00oC I,-0C 0)00> f7 )(NNN,14NNNN( 1I0 o(0-4 tig>- LL- 000o - Nt ý <U- (0 in -J >(0o In4. 0y) 44 xaCp000000 CL if I(00-4...007 W10 M 1 )-4 -TM f7 - -400 "d N"t, -If N 4 40( N -4NC .4 -4040)0N0040- -ION N l 4-4 in 0 -4 ൏ NIO it xo - 0 NI0 I 0. 1 0 00 -4-4 NOCIA0 -4o N-I -4N

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 19 (Swanda Brothers Incorporated-TRT Telecommunications Corp)

DTIC Science & Technology

1990-01-01

0000000000 400c 00) -4000C20 (400000 N44V 010 "- K W Io0-4 Kfc oc a c In00000 i4 00 oo %nw 00 000000 0000 (30 Ji K a 1 0-4 KH00000000000 -W4C4- CD0 anw000...44440444444UUU44444 Kf I W-ONO KIf KfC t -4 -4N K. N K I M-40410 K11 K I 00-4iri4I &, mO &n o In in in in 0 In o inY) )ofIn in in o In In 0 DIn 0oIn In...44444444444444 N44 4 *ON co a 4 .- c) in di n I n t t i i An in t mnam bfIn wi wi wmi wa w) wI In in Infin in in In0 S doaN w4 4’m 113(’ a C) VMmmMV MI

Department of the Navy FY 1995 Budget Estimates. Justification of Estimates, Research, Development, Test and Evaluation, Navy Descriptive Summaries

DTIC Science & Technology

1994-02-01

t,- r- 0N o 1nCO10 in %D ’DatLin 0 H-0 -4 ’ 100 o o% it -4 NoI c4 01- o ja iv 0 -14 H 4 ý4 .-4 - 4.j .-- .-4 .I.4 -H - 0 . 4 ~0 4 z z4 Cn E4-4- Oz~0...N (N(40( 4MM MM MHO F4t4W > 1% (N4 r4 E’ M 4 z E-4 0 t 00000 00000w000000000z 0000 1010 010.0 m00011 u 0100to 0as, 0 . z0( N 100 w0C’ 000000000000000...H 0. 04 04 0 w- 100 4 -0 4 ac 0% n~U .- 40% i -4in a inN . I in00 -4- ~.-4N -4 ). 4-4-..4~4-0inini 4 n -1 -- 00 Oi n4 n~i 000000 O000000C6000000>040

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 20 (Tru & Associates Inc-VTM Group Joint Venture)

DTIC Science & Technology

1990-01-01

000w0c0000000w ( 0 6 S Coco to t to 00000 c, -0000.00.J 04 NN - N000NNCJ 04 000000000 00000 WW U SY NN N N N 4 4 C91000 000000cl.0 40 050 00 0 a0 0 0C 4 O...If106000 N4 06 -a M.’ 4 400 cl NV Mqt CI1- 0t SY MI-I.-IF- Sn-4 "- N W 0I N 000S4o-I CAN 10 000 0oCo 600 3Ni In6 < O OM UUUUm COOw 11 .1 NS 064C U-a...00a1.6 r-2 = Nabe O U0 I 4NC U I 1C)050.410󈧒 Wq(0 I w to0 I C’) ow 0 1 -I I 0 I0 0U I 0 4N U~Nocc0001-004n0Nl-INO -4 M(Y) 0D0 G 01- r-_-1 -40 M01

Prime Contract Awards by State or Country, Place and Contractor. Part 7 (Lake Park, Georgia - New Haven, Indiana), FY1991

DTIC Science & Technology

1991-01-01

4 N3- 4 U n t -C 1.U.00 00L00 * 0Goa oCI LAdo .C000 4 G-4 00 -4 WW4 L.4000 0L o 30 U in0(Y) U, 0 -4-4-4-4-4.4CF 0 0M - 00 0 M f 044- (Dcu4 01 UI (U0...m rfin In in tri j3li I M) 1 16-1-4 N-4 - 00 enC 0 -4- m-N N N4-4- 1 - 4- - 4- -4 --4-4 4- dI 6) I I Im~ 1 4 1I -N 0 -4 CL 4 - 4 -0 ccw r-t- 1" w 0 m...4 -4NN4N4C UN4 uD U-1 -4- 4-IN .4- 4 O -4 1 0 K 1, () 4 0 C. l u ) i N4 0 -in 000 = - =D mN 31 Pi-.- -4 ENC - 0D K 0. 1 04t Km -0 1- .1 -0Cl 1- 0 1-0

Syntheses, structures, and 1H, 13C{ 1H} and 119Sn{ 1H} NMR chemical shifts of a family of trimethyltin alkoxide, amide, halide and cyclopentadienyl compounds

DOE PAGES

Lichtscheidl, Alejandro G.; Janicke, Michael T.; Scott, Brian L.; ...

2015-08-21

The synthesis and full characterization, including Nuclear Magnetic Resonance (NMR) data ( 1H, 13C{ 1H} and 119Sn{ 1H}), for a series of Me 3SnX (X = O-2,6-tBu 2C 6H 3 (1), (Me 3Sn)N(2,6- iPr 2C 6H 3) (3), NH-2,4,6- tBu 3C 6H 2 (4), N(SiMe 3) 2 (5), NEt 2, C 5Me 5 (6), Cl, Br, I, and SnMe 3) compounds in benzene-d 6, toluene-d 8, dichloromethane-d 2, chloroform-d 1, acetonitrile-d 3, and tetrahydrofuran-d 8 are reported. The X-ray crystal structures of Me 3Sn(O-2,6- tBu 2C 6H 3) (1), Me 3Sn(O-2,6- iPr 2C 6H 3) (2), and (Me 3Sn)(NH-2,4,6- tBumore » 3C 6H 2) (4) are also presented. As a result, these compiled data complement existing literature data and ease the characterization of these compounds by routine NMR experiments.« less

Let-7i attenuates human brain microvascular endothelial cell damage in oxygen glucose deprivation model by decreasing toll-like receptor 4 expression.

PubMed

Xiang, Wei; Tian, Canhui; Peng, Shunli; Zhou, Liang; Pan, Suyue; Deng, Zhen

2017-11-04

The let-7 family of microRNAs (miRNAs) plays an important role on endothelial cell function. However, there have been few studies on their role under ischemic conditions. In this study, we demonstrate that let-7i, belonging to the let-7 family, rescues human brain microvascular endothelial cells (HBMECs) in an oxygen-glucose deprivation (OGD) model. Our data show that the expression of let-7 family miRNAs was downregulated after OGD. Overexpression of let-7i significantly alleviated cell death and improved survival of OGD-treated HBMECs. Let-7i also protected permeability in an in vitro blood brain barrier (BBB) model. Further, let-7i downregulated the expression of toll-like receptor 4 (TLR4), an inflammation trigger. Moreover, overexpression of let-7i decreased matrix metallopeptidase 9 (MMP9) and inducible nitric oxide synthase (iNOS) expression under OGD. Upon silencing TLR4 expression in HBMECs, the anti-inflammatory effect of let-7i was abolished. Our research suggests that let-7i promotes OGD-induced inflammation via downregulating TLR4 expression. Copyright © 2017 Elsevier Inc. All rights reserved.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1987. Part 14. Okinawa Kankyo-Pultrusions Corporation.

DTIC Science & Technology

1987-01-01

1 00 aca Y. 0 139-4-4M ᝰ  ɘ-4-400-4-4-f 1(2 z 0 I= 09 Cie w I -IC Cn 10-4 w U 000 0 r, 0 0 1 4c cn 1 4c C-) cn ZLn com -4-0-0 0.00 CL in 0 0 (L...0 No N N) (O(ONNC ". N1 NL C -I 4 (nI Z- -’ A Mz - COm 0140 -4,- n( I o )MN&1 0 I n 00 04 - J " cc t 0140 1(4 14C .4’ NNN NN 80104000 0-4 N () 0 (0 V...j 0 0 .4 0 00 MO 3 0 <-Cc00m-cc-c <- x, ~4.-C < x-I-x-C < < 0 N 0N 3 0N ON 1- 0 304 Com 004 0.4 l’ 0 ) 0- t- - 0 0 1’ ) 1-o 0 0 0 3 30 *4U, 0 0 0) -4

Prime Contract Awards by State or Country, Place and Contractor. Part 13 (New London, Ohio - Westerly, Rhode Island), FY1991

DTIC Science & Technology

1991-01-01

u I (04q N -iLifLn-i0)00 .- Cl) -- If .’t- -- 400 r1I- -4-. M(𔄁 . "I XN 1,- 1I to I (04e 11 1f4.-400𔃾 in -f o~n InJ N L0304 toN 0n (no U O 4 vUN 0...o CN M C) a) "൒ -’ 14"to0" C>(W P 00(W0t- 00m 0- --4 C~nC’ r-- KooN 400 0 -4-4 a0(D0)( w 4(1(0 -4 * 4m( 0-4 m0000000CC>C0 -4"K 4OI 41 CC D>)- 000C

Alloionema californicum n. sp. (Nematoda: Alloionematidae): a new alloionematid from USA.

PubMed

Nermuť, Jiří; Půža, Vladimír; Mráček, Zdeněk; Lewis, Edwin

2016-11-07

A new species of the family Alloionematidae was isolated from a rotten winged gourd at White Crane Garden, San Francisco, USA, sampled by Christopher Nelson in November 2010, and a live culture is deposited in Félix Lab Strain Database (http://www.justbio.com/worms/index.php), IBENS, Paris, France. Specimens from the culture have been examined. Both morphologically and molecularly, the nematode described herein as Alloionema californicum n. sp. differs from the other alloionematid species, A. appendiculatum and Neoalloionema tricaudatum. It is characterised by having a narrow stoma, 2.5-3.5 or 4 times longer than broad in adults or dauer juveniles respectively. Lateral fields are not present in adults but occur as one prominent ridge in dauers. Males have no bursa, six pairs of genital papillae and one single papilla. Dauers have large apparent phasmids in the middle of the tail. The ecology of the newly described species is unknown but probably it is a saprobic bacteriophagous nematode preferring rotting organic material.

All Prime Contract Awards by State or Country, and Contractor. Part 7. (Adel Georgia - La Grange Illinois)

DTIC Science & Technology

1990-01-01

Ien’) I C)(o0)N00.-40oC’) 0 -iN4 C’ ) In .-4 00 T’ 0000 11I 1 IeC )- Ir Oi404-i" N - C’) 0> N 00 1i Iec (, it 0 -4 N CN ) In t0) 00I,_ ON)l 0 -4 Tr(0 vt...N 2N Z* 0-4 ZN c" D-4 U) 11. o zo 61010 - C> 0000 .40 cno000 ILOC 1-40 (00 40 00, LL M( -.1 ck -4 W-1U0-11 I KL) .000 4ɘ -000 20 0 0) -to co0 ZNC 1

Intergenerational transmission of family meal patterns from adolescence to parenthood: longitudinal associations with parents' dietary intake, weight-related behaviours and psychosocial well-being.

PubMed

Berge, Jerica M; Miller, Jonathan; Watts, Allison; Larson, Nicole; Loth, Katie A; Neumark-Sztainer, Dianne

2018-02-01

The present study examined longitudinal associations between four family meal patterns (i.e. never had regular family meals, started having regular family meals, stopped having regular family meals, maintained having regular family meals) and young adult parents' dietary intake, weight-related behaviours and psychosocial well-being. In addition, family meal patterns of parents were compared with those of non-parents. Analysis of data from the longitudinal Project EAT (Eating and Activity in Adolescents and Young Adults) study. Linear and logistic regressions were used to examine the associations between family meal patterns and parents' dietary intake, weight-related behaviours and psychosocial well-being. School and in-home settings. At baseline (1998; EAT-I), adolescents (n 4746) from socio-economically and racially/ethnically diverse households completed a survey and anthropometric measurements at school. At follow-up (2015; EAT-IV), participants who were parents (n 726) and who were non-parents with significant others (n 618) completed an online survey. Young adult parents who reported having regular family meals as an adolescent and as a parent ('maintainers'), or who started having regular family meals with their own families ('starters'), reported more healthful dietary, weight-related and psychosocial outcomes compared with young adults who never reported having regular family meals ('nevers'; P<0·05). In addition, parents were more likely to be family meal starters than non-parents. Results suggest that mental and physical health benefits of having regular family meals may be realized as a parent whether the routine of regular family meals is carried forward from adolescence into parenthood, or if the routine is started in parenthood.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 15 (Mountain States Caulking Inc-Pangborn Corp)

DTIC Science & Technology

1990-01-01

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Revised Height/Weight Sizing Programs for Men’s Protective Flight Garments

DTIC Science & Technology

1979-04-01

V 0 4 HHH HHH H-HT rIrIr- - -4 NN 04i$ 04 - 𔃾 E-’ 0)4 Hl m II I III I IlI I II k 0 [ xl :Iz U() -4C , C) 0>’D) C, 000 000 000 0 0 1" (0C N2 0 04 CN... xl - to 0 ajg ). 14P)f 4 m i-j C oP) t 0 t 0-. N aa H H N 00 Lii <- V) .4 Z. aI- : LI- N , . W. Wl 0 ŕ mI C CD0z IL C wA0ICO ~ ~ ~ ~ J toA C ~C o N to...LiL U)- 0 x4 9 0) I Lu WI c.o~ to~0. 04 1-- 0 U)M*gtov 0II to 40t 0II- .4 Xl ; *0N4 IL oWES MC c I-- w ( 0 lot 3. "I LL I Xwl 0 " LL4 N 1- 1 04 N 140 w

Methods of producing epoxides from alkenes using a two-component catalyst system

DOEpatents

Kung, Mayfair C.; Kung, Harold H.; Jiang, Jian

2013-07-09

Methods for the epoxidation of alkenes are provided. The methods include the steps of exposing the alkene to a two-component catalyst system in an aqueous solution in the presence of carbon monoxide and molecular oxygen under conditions in which the alkene is epoxidized. The two-component catalyst system comprises a first catalyst that generates peroxides or peroxy intermediates during oxidation of CO with molecular oxygen and a second catalyst that catalyzes the epoxidation of the alkene using the peroxides or peroxy intermediates. A catalyst system composed of particles of suspended gold and titanium silicalite is one example of a suitable two-component catalyst system.

"Where Is My Daddy's House?" Preschool-Age Children of Divorce and Transitional Phenomena--A Study.

ERIC Educational Resources Information Center

Stirtzinger, Ruth

1986-01-01

Presents study comparing preschool-age children of divorce not living in family home (N=4) with children (N=4) remaining in home. Those not in home showed specific discrete longing for it. After divorce the family home may allow the preschool-age child the necessary mental image of access to both his parents despite decreasing family structure.…

Anthropometric Survey of the Imperial Iranian Armed Forces. Volume 2. Statistical Data

DTIC Science & Technology

1971-03-01

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All Prime Contract Awards by State or Country, Place, and Contractor, Fiscal Year 1985. Part 20 (Antilles - Israel).

DTIC Science & Technology

1985-01-01

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Development and Evaluation of Adeno-HTLV-III Hybrid Virus and Non- Cytopathic HTLV-III Mutant for Vaccine Use

DTIC Science & Technology

1988-10-28

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Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 7. (Fahey Watts Architects-General Contract and Sales)

DTIC Science & Technology

1989-01-01

0 -m Il 5 ))40 . I: 0 40-4-4 -x000) of I 00-4qN< 66 ."eN *-4NI g - *N .40)-4 .4 U1.4 MOMO t00 m m’ C-eq an .- 4-4 eqI 0 .-44 1 ::-4...991 M (0N lice x W (A 4 4C (5n ( U) n44 1-44e mlt w. < Z 91 (0N eq4 c 0 a >- 0 0u >- >- 00X 1- 0 1-0o 1- cc I-- 0 0 C I M C14 91 -4 W. cc . 5 0D 0 -. 1 .1...001 - 00 IO 0 ( NC1n1- 1-1 C90 1 M 4 I 9(no0 1-- 0 4C 0 . 4 4 ~i 0 - 5 <C 4 ZNNZ 0 91 0 j

Family Correlates of Adjustment Profiles in Mexican-Origin Female Adolescents

ERIC Educational Resources Information Center

Bamaca-Colbert, Mayra Y.; Gayles, Jochebed G.; Lara, Rebecca

2011-01-01

This study used a person-centered approach to examine patterns of adjustment along psychological (i.e., depression, self-esteem, anxiety) and academic (i.e., academic motivation) domains in a sample (N = 338) of Mexican-origin female adolescents. Four adjustment profiles were identified. A "High Functioning" (n = 173) group, which…

List of Inspected Tank Barges and Tankships

DTIC Science & Technology

1980-01-01

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Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acrylamide in human colorectal cancer cells in vitro and in vivo

PubMed Central

Chen, Chun-Han; Lee, Chia-Hwa; Liou, Jing-Ping; Teng, Che-Ming; Pan, Shiow-Lin

2015-01-01

Upregulation of class I histone deacetylases (HDAC) correlates with poor prognosis in colorectal cancer (CRC) patients. Previous study revealed that (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acrylamide (Compound 11) is a potent and selective class I HDAC inhibitor, exhibited significant anti-proliferative activity in various human cancer cell lines. In current study, we demonstrated that compound 11 exhibited significant anti-proliferative and cytotoxic activity in CRC cells. Notably, compound 11 was less potent than SAHA in inhibiting HDAC6 as evident from the lower expression of acetyl-α-tubulin, suggesting higher selectivity for class I HDACs. Mechanistically, compound 11 induced cell-cycle arrest at the G2/M phase, activated both intrinsic- and extrinsic-apoptotic pathways, altered the expression of Bcl-2 family proteins and exerted a potent inhibitory effect on survival signals (p-Akt, p-ERK) in CRC cells. Moreover, we provide evidence that compound 11 suppressed motility, decreased mesenchymal markers (N-cadherin and vimentin) and increased epithelial marker (E-cadherin) through down-regulation of Akt. The anti-tumor activity and underlying molecular mechanisms of compound 11 were further confirmed using the HCT116 xenograft model in vivo. Our findings provide evidence of the significant anti-tumor activity of compound 11 in a preclinical model, supporting its potential as a novel therapeutic agent for CRC. PMID:26462017

Prime Contract Awards by State or Country, Place and Contractor. Part 14 (West Warwick, Rhode Island - Katy, Texas), FY1991

DTIC Science & Technology

1991-01-01

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All Prime Contract Awards by State or Country, Place, and Contractor, FY 88. Part 9. (Athens, Maine-Woodbine, Maryland).

DTIC Science & Technology

1988-01-01

Mon MOlA mIooo (00 (000000 (0 00 (0 (000 (0000000000 IW001(mo(0 W00000000 (00 WO000 mo00 mo00 000000000 I(00LA41 0 0000000 0 000 00 00 000000000(fl(0LA4...tv. - 4- 4 4q r.4q 444l 4q. vC .Ct .44v 4444-4av T-a8 MOLA (0 I -(1N4NN l -N j -NN 4N 04 NNNNNN 0 "CVNN NN N N NNN NN4N0 4CJC- ~ l V"N N "N N I(Oin< wL...4 0"t -0 󈧈 44444 -04 V0 𔃾 V V 0I (00InCO i cNNNNN"~ CN EN EN C4NNNN cN .N .N .ENl 1 l cc c cC c0 0 1 (00In< i V00000 -4 0 to Ln MOLA M ’Wn Ln on n

Microcomputer Based Ship-Board Gun Control System.

DTIC Science & Technology

1981-03-01

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Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (HSU Ronald Construction Co. - Jacobson & Son Yard Service). Part 10

DTIC Science & Technology

1994-03-01

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Prime Contractors with Awards Over $25,000 by Name, Location, and Contract Number. Part 6. (Kenett Corporation-Mid South Dredging, Inc.)

DTIC Science & Technology

1989-01-01

o 04 - a. 4CJC zAw IL I 0.H 8 :3~~ z I0 0.DC 49 .I QE C-) w z zn 04. .. .4.4.4 . 44 ~ t .00.0c. -3 cc) C> t10 N r- OD C,-4 IZD CD - 0n 00 040 -O...U 4-4 4- - tun OD 0 m4 00 C)I C0 0 OD N0 -4t ) DO U) 4 (Ii tc CtD( -C -4 OD -DC tNkn ( IQr-O N0 c. ( z oe) 6 -r- 0) -Cjj < 0 4 4 m4 -4t 0 O m- t4 (n...r0 N n 00 L)) 0 00 0) 0 0 0 C6EuI C 40 . tun a, U - UrC 400 0% 41 4.- v1 0 )Z( 1 ,, Cli (no 0 4i W0 L- 3U 4 0 0I 0 I a. am u. U 0 0- H-I -CrU t wC0. UZ

Robust Multivariable Controller Design via Implicit Model-Following Methods.

DTIC Science & Technology

1983-12-01

followers, such as: II-7 , Ai ".......... . - ,. * . . , -. ,., 4’ . L7 XJ •:-, - J - / ( -+(Y -m)-- ( _ym + UTUc-]dt (11-13) A design method based on...Im r4 aI AI wS I I C.) 0 N 0N ON0N% I4 A’. I 0L- t-00 o% 0 ON 000 LA0 Naj UzN W4 c * r- In Go .% m * m . \\ C-. 0 cm a 0 ’no L- 00 *- \\ 14 0 0 ’-C Go N...0 t’. ~ - V’’. LALA -f . ONZ LA 41 0 \\ NL 0n I a A A N aI ’ nN? Z . =. 4 1 -I -0 I. I %a .0 1 - .a to. ot .b t o ob oto ob o11 cc-. "-f cccX dc c t I

Unsociable Work? Nonstandard Work Schedules, Family Relationships, and Children's Well-Being

ERIC Educational Resources Information Center

Strazdins, Lyndall; Clements, Mark S.; Korda, Rosemary J.; Broom, Dorothy H.; D'Souza, Rennie M.

2006-01-01

Many children live in families where one or both parents work evenings, nights, or weekends. Do these work schedules affect family relationships or well-being? Using cross-sectional survey data from dual-earner Canadian families (N=4,306) with children aged 2-11 years (N=6,156), we compared families where parents worked standard weekday times with…

Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (American Telecom Corp - Barker Frank Associates). Part 2.

DTIC Science & Technology

1994-03-01

n 0 a)N NN ION (~ Y( " ( - oN " -11WLJIC 100.4 I(1 N N N N (0( 0 YC YC i(0 (00 -0U~ -qa000000 If)n)0 0) 0)0C) v C.O leNr -.1. N to I w00-4 11 1,0 000...WOOO-4 4W0 I m0 1 o 0N 4 n cn 0 e.-I leNr * " 4j 1 0 cm 11 to t100 e40000 1 0o o 10 0to 100000 10 10 I,1-KU 1 - 110 0 0 -w 4 41’ w Vcn 11 1 1 cn)eU It

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 88. Part 7. (Eastport International-Flint Electric Membership Corp.)

DTIC Science & Technology

1988-01-01

0 00--400000000000000-40000000000 0 q’mwavI m 00 00000(00000000000000000(0O ANIWOV I (00400550 1 0 0 5 0 t~sWOqU I NNNM C𔃻".)O)a s...4 N J 5 ’ 5 M - -4 1100-4 1 040N ,-4 N4 N 44444444-l444444444---------- -4 1 0 -40 1 <  <<ɜ< 4c 190-40 1 -4 -4- -44-4 -4 -4 -4 es!-4 -4-4 -4...009’.. I NNIN-4 NS N (7N4-4 NNN.- Cl- INN-4 "-4-4 -4 .J4 " NN NNNNNN4NC 0 N 󈧄o( 0 I >->->-"- . 5 .’ . . ....... D.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1985. Part 11 (International Computer Corp - Kloze N S Inc).

DTIC Science & Technology

1985-01-01

N 0 mC. m.( m( m0 C) (0 (0 (0 0 Nf.0 r. cNNr4NO (0 en (0 MSP (0 *50 -W (0 -1 0 0 0 0 NC) 000 0 "-4 0 I(( (0 (1 1) P7 L) (0 in 4. -.4-4 m -& (D U (0... acCA -4N NN CcC4c xC4 NN N4 10L 0 ( Z-4 -I 4N . ".. (0 N 1-.U -4 .4 co -lOI m a) a) mne M 0. N r. I0 I0 I 0- 0. nc c n CI C% 004 0 00 0 04 " "N . .0

Snakefly diversity in Early Cretaceous amber from Spain (Neuropterida, Raphidioptera)

PubMed Central

la Fuente, Ricardo Pérez-de; Peñalver, Enrique; Delclòs, Xavier; Engel, Michael S.

2012-01-01

Abstract The Albian amber from Spain presently harbors the greatest number and diversity of amber adult fossil snakeflies (Raphidioptera). Within Baissopteridae, Baissoptera? cretaceoelectra sp. n., from the Peñacerrada I outcrop (Moraza, Burgos), is the first amber inclusion belonging to the family and described from western Eurasia, thus substantially expanding the paleogeographical range of the family formerly known from the Cretaceous of Brazil and eastern Asia. Within the family Mesoraphidiidae, Necroraphidia arcuata gen. et sp. n. and Amarantoraphidia ventolina gen. et sp. n. are described from the El Soplao outcrop (Rábago, Cantabria), whereas Styporaphidia? hispanica sp. n. and Alavaraphidia imperterrita gen. et sp. n. are describedfrom Peñacerrada I. In addition, three morphospecies are recognized from fragmentary remains. The following combinations are restored: Yanoraphidia gaoi Ren, 1995, stat. rest., Mesoraphidia durlstonensis Jepson, Coram and Jarzembowski, 2009, stat. rest., and Mesoraphidia heteroneura Ren, 1997, stat. rest. The singularity of this rich paleodiversity could be due to the paleogeographic isolation of the Iberian territory and also the prevalence of wildfires during the Cretaceous. PMID:22787417

Annual Report 1983.

DTIC Science & Technology

1984-01-01

Ft- Vi9i m4V r i 4 - 4 P. 04" Vie Vi bl I- VilO~~~C 4 44ii ~ ~ V : A Vi". . st~ 󈧬 04 ie 4N. 0@ PP 4’ A P .. V i 𔃺 itp 4 V? VN V~ 𔃾 -- T Vi~i 37 400...In aD (0110 ffO Inc-an c* c.c- 1 ON d r3’ .In C4 IN c-a. ŝI vn -1~ ’o -. --i c- nON c-.n4 I 1 C!~ N- Ibm --~- -I. 1 ) n r - r4 D1- 10( Ci 4I 1tO1 .9I...have been developed for the IBM 6195 and the Data General S14U systems. A coder for the Corps’ Harris computers should be available shortly. Examples

Prime Contract Awards Alphabetically by Contractor, State or Country, and Place. Part 8 (Giordano Associates Inc, Long Branch, New Jersey - Hewlett Packard Company, Cupertino, California), FY1991

DTIC Science & Technology

1991-01-01

0F- CDin in V0 55 I (0-I U 41000* 0- F-3-r 4 - InIL. Ln f4 F-LLI-4.-4f-F- ". U 0L I M-4 U 4-I0 F- F-4 04 InU.4c 04 = O w I4n400... 4 : (0-4 U W- InIIL...1cI- I.- F- I.- 0D I- I- hi I M i-4 a 2( 20 O 20 ZOCCCOOOOOOOO 0 zOWWQDQDCOOOOOI U3 1 S i-4 55 c% WN"h4 W -4 w - 4 MCMrM)M.MCM)M’M-4 4 4 4 hi -4 hi-4-4...0 0 00 0 0 00 0 0 00 0 0 M- 55 i-4 II mm ic x x xx xx x (n NI in4 N -400 -40CD -440 -4 00 0 00 C 0 00 0 0 0 000 .4ɚ 0aC 4 D0 00 000 4N S n0-I K 000A

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 3 (Ashley Steel Inc-Bettencourt R E Inc)

DTIC Science & Technology

1990-01-01

Jin -JIn -j In -j In -1 O -. 100 -. 1000 I,. Hf - M (-4 Hic -.1JC ~In -JO0 . JCI -J in -.i n .1(1 -i in -JO0 . .04 .J044C C)~ 11(0M-4 ’wCD w LC W0...co 10.oc *< < 04-. <g < 4 4c 4( < � in- inIB- N N NNNNNNN con 004Co 100 * I0-4C)0B00 0 000 00 0-0 00 C00000C000 0 *I-4 Cl0 0c 0 000 0 0. 0...oI 011 0JN 0 r- r- -. 0cI 00 0.4 0 " NNN C S S N CYINSC4 04 NS C4 - M 0-4"ə L- a WjIn .. (D(0(0 CC4 >.N XN ( -000000 0 -N 1 100 -4N4 lUli < tg N -4C

The Army Study Program.

DTIC Science & Technology

1983-05-31

a- - - - - m .aKU i~ n I n i n K K iK G. (J- zow w w w m m cc co n CD a) w u u w w w v IA a :aP aj I 4p . V 4 p IV V A 4 4 v I . V a t1 1 4 acca n...xi W Uc -K. U4 0-0)0- 0- 4 -01 4 02 - n U ) U x14 4, 04:1)6 hi u 0) ki V3 1 z- P7 a. ** hi * U,0 .04 K hi 0 Z) hiJ 0. U W 9 4 W 0. U a Cc z A. 4A 0

4. Historic American Buildings Survey, N.E. Baldwin, Photographer, November 1939, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Historic American Buildings Survey, N.E. Baldwin, Photographer, November 1939, GENERAL VIEW OF WATERVLIET SHAKERS SOUTH FAMILY, FROM BARN - closer-up, Gift of New York State Department of Education. - Shaker South Family, General Views, Watervliet Shaker Road, Colonie Township, Watervliet, Albany County, NY

Investigation of magnetic properties in the case of three families of 1-dimensional magnets: M(II)A(4,4'-bipyridine); M = iron, cobalt, nickel, copper; A = chloride, nitrogen, (ox)

NASA Astrophysics Data System (ADS)

Danilovic, Dusan S.

Magnetic properties of three families of metal-organic coordinated networks which have the general form of M(II)A(4,4'-bipyridine), where M=Fe, Ni, Co, and Cu and A=Cl2, (ox) and (N3)2, are studied in this dissertation. Novel Ni(N3)2(4,4'-bipyridine), Co(N3)2(4,4'-bipyridine) and Cu(N 3)2(4,4'-bipyridine) have been synthesized. We applied different synthesis procedures and produced Ni, Co, and Cu azide compounds for the first time, thus leaving the hydrothermal route procedure. Powder x-ray diffraction at room temperature was done in order to establish the crystal structure of the members of these three families. It was found that all of them crystallize in orthorhombic structure, where transitional metals have an octahedral coordination. Since all three families have identical crystal structure we got opportunity to examine how ligands facilitate magnetic interaction between metallic centers and also to test existing magnetic theoretical models. Since 4,4'-bipyridine is much longer than other ligands, our systems can be considered as 1-D magnetic systems. Their interchain magnetic interactions are very weak, and they order magnetically at very low temperatures of the order of few K. Measurements of M(H) at temperatures T=1.9K and T=2K and chi(T) in different external magnetic fields in zero field and field cooled modes have been made. In the case of MCl2(4,4'-bipyridine) family of compounds, we observed ferromagnetic interactions between metal ions within the chains and antiferromagnetic interactions between adjacent chains. M(ox)(4,4'-bipyridine) family of metal-organic compounds has antiferromagnetic interactions between the transitional metal ions within the chain, while weak ferromagnetic interaction exists between the chains. All members in the M(N3)2(4,4'-bipyridine) family except in the case of the copper compound were found to have ferromagnetic interactions between metal ions within the chains and then antiferromagnetic interactions between adjacent chains. The copper compound does not show magnetic ordering in the temperature range we considered. All the metal ions in these compounds were detected in high spin states. The magnetic susceptibility data was fit to appropriate 1-D models, which in the case of MCl2(4,4'-bipyridine) and M(N3)2(4,4'-bipyridine) were the Classical Spin Fisher model, and the Bonner Fisher model in the case M(ox)(4,4'-bipyridine). The experimental results and fitting to the appropriate model with the accuracy of 0.995 suggests that shorter Cl-M-Cl distances facilitate ferromagnetic interactions, which are more sensitive to the total spin value then to the sole distance between metal ions. The magnetic behavior of M(N3) 2(4,4'-bipyridine) family of coordinated metal-organic compounds is very interesting because family members exhibit both ferromagnetic and antiferromagnetic behavior. The ferromagnetic characteristics decrease with decreasing spin. Fitting the results for all compounds of the M(ox)(4,4'-bipyridine) family have shown that strong anisotropy exists in all of them, being highest in Ni(ox)(4,'4-bipyridine) and lowest in Co(ox)(4,4'-bipyridine). Specific heat measurements were performed in the case of cobalt and copper azide compounds and then compared with previously obtained results for the iron coordinated network of the same family. Although none of these compounds show the characteristic lambda shaped transition indicating magnetic ordering, all of them have unusually large values of the constant gamma, which indicates significant magnetic contribution to the observed specific heat, since the free electron contribution in these observed families is negligible. We have concluded that total spin of the transitional metal plays a more important role than the distance between ions within the chain in determining magnitude of interaction, and that (N3)2 is a better facilitator of ferromagnetic interaction between ions than Cl2.

All Prime Contract Awards by State or Country, Place, and Contractor, FY 85. Part 6 (Alachua, Florida - Winder, Georgia).

DTIC Science & Technology

1985-01-01

4aC I 00 < M Uz 00(000000cc0000000001. U 0LALLAAOO 104I < 40(0OO0O4NN0.I-C10 ml W N00NNNN-4-I - M I .00 . . ~ .’l ~ C 0 0 .0- . .. . WWW W0r.000O LA...40 -4 -4 -V4I, 0.2c W~n r-. CLn U). C CC rA. IA. I ca 0 sO N 4 r4-4 4 --*L -qU l4 .00)L . m -IU NY mQ 4 *ww4CI www "Mm<)C, C’ oC)Co ) -IC44 -40 .. 40)C...10 ) -4 0 N 0 * C 1) 0 0N0 0 N 0 0 00’ mo oo* 𔃺 (0’ 4-’ in L4)4)-)- -n =0 0 0M- =OO- = 0. 30w~ww -4c) -4w www -40) -4-4n~ - -4mmac L44 0-- 403 01 0

All Prime Contract Awards by State or Country, Place, and Contractor, FY 85. Part 5 (Arapahoe, Colorado - Washington, D.C.).

DTIC Science & Technology

1985-01-01

444444. < MW 0 U 0. U <- OU cI- 0 < :412 8-4 M" I= Ul N >9 ? -4 cc0 a* N - 00 W(0 w.1 co. o U jNNc)InD9- i901I 00 0-4 <-4 Ufl." 20 > -4 ado 30 CI0 1... Porno .....) 4 : W&P 040( 0-I4 4004444 44040000004-44-40.44.44.44-44.44.--4-4.4.4-4.-44-4-4.40.44- I.- do I I a -’ ~ ~ N I , ICPN -440flOo r ntOO40 0-N

Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (W & G Machine Co. nc. - Zycad Corporation). Part 20

DTIC Science & Technology

1994-03-01

c.JN- W)’ " L ncqc ncn Vcn )s-4 Lii de I a I O Mow -11 " ’-I-- - - I- In- 02) o- ’-4 (()0)M (1010))n)0)) I’_ 1,- 11 # coo Ny 0 4c & cc 4 w f M -C (0(0...11<WF. ’ 0( -IN~n~n 4N.4.~404I 4 to <( I-- 0 1-- 0.1 l’- If! W(ON 1ZI D( X23v- eC >:I. z~ n > 3-> z > x XO a x De > 0 u " (0Oa I 0 0 0...0u00...0- CL CL CL U L) L) " N I wo" 00 L) 3c 0-4 W N I wo-4 NIB < w 0 -1 < ce Cie cc 0 _4 CL V Cn OD (D tn Ln I-to > rý 3c 0) LLIOC)OOO Lu Ln z qw z co11

41 CFR 301-31.7 - May my family and I occupy lodging at different locations?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false May my family and I occupy lodging at different locations? 301-31.7 Section 301-31.7 Public Contracts and Property Management...-THREATENED LAW ENFORCEMENT/INVESTIGATIVE EMPLOYEES § 301-31.7 May my family and I occupy lodging at different...

Caspase-6 Activation in Familial Alzheimer Disease Brains Carrying Amyloid Precursor Protein, Presenilin I or Presenilin II Mutations

PubMed Central

Albrecht, Steffen; Bogdanovic, Nenad; Ghetti, Bernardino; Winblad, Bengt; LeBlanc, Andréa C.

2010-01-01

We previously demonstrated the activation of Caspase-6 in the hippocampus and cortex in cases of mild, moderate, severe and very severe Alzheimer disease (AD). To determine whether Caspase-6 is also activated in familial AD, we performed an immunohistochemical analysis of active Caspase-6 and Tau cleaved by Caspase-6 in temporal cortex and hippocampal tissue sections from cases of familial AD. The cases included 5 carrying the amyloid precursor protein K670N, M671L Swedish mutation, 1 carrying the amyloid precursor protein E693G Arctic mutation, 2 each carrying the Presenilin I M146V, F105L, A431E, V261F, Y115C mutations, and 1 with the Presenilin II N141I mutation. Active Caspase-6 immunoreactivity was found in all cases. Caspase-6 immunoreactivity was observed in neuritic plaques or cotton wool plaques in some cases, neuropil threads and neurofibrillary tangles. These results indicate that Caspase-6 is activated in familial forms of AD, as previously observed in sporadic forms. Since sporadic and familial AD cases have similar pathological features, these results support a fundamental role of Caspase-6 in the pathophysiology of both familial and sporadic AD. PMID:19915487

Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease.

PubMed

Martin, E R; Scott, W K; Nance, M A; Watts, R L; Hubble, J P; Koller, W C; Lyons, K; Pahwa, R; Stern, M B; Colcher, A; Hiner, B C; Jankovic, J; Ondo, W G; Allen, F H; Goetz, C G; Small, G W; Masterman, D; Mastaglia, F; Laing, N G; Stajich, J M; Ribble, R C; Booze, M W; Rogala, A; Hauser, M A; Zhang, F; Gibson, R A; Middleton, L T; Roses, A D; Haines, J L; Scott, B L; Pericak-Vance, M A; Vance, J M

2001-11-14

The human tau gene, which promotes assembly of neuronal microtubules, has been associated with several rare neurologic diseases that clinically include parkinsonian features. We recently observed linkage in idiopathic Parkinson disease (PD) to a region on chromosome 17q21 that contains the tau gene. These factors make tau a good candidate for investigation as a susceptibility gene for idiopathic PD, the most common form of the disease. To investigate whether the tau gene is involved in idiopathic PD. Among a sample of 1056 individuals from 235 families selected from 13 clinical centers in the United States and Australia and from a family ascertainment core center, we tested 5 single-nucleotide polymorphisms (SNPs) within the tau gene for association with PD, using family-based tests of association. Both affected (n = 426) and unaffected (n = 579) family members were included; 51 individuals had unclear PD status. Analyses were conducted to test individual SNPs and SNP haplotypes within the tau gene. Family-based tests of association, calculated using asymptotic distributions. Analysis of association between the SNPs and PD yielded significant evidence of association for 3 of the 5 SNPs tested: SNP 3, P =.03; SNP 9i, P =.04; and SNP 11, P =.04. The 2 other SNPs did not show evidence of significant association (SNP 9ii, P =.11, and SNP 9iii, P =.87). Strong evidence of association was found with haplotype analysis, with a positive association with one haplotype (P =.009) and a negative association with another haplotype (P =.007). Substantial linkage disequilibrium (P<.001) was detected between 4 of the 5 SNPs (SNPs 3, 9i, 9ii, and 11). This integrated approach of genetic linkage and positional association analyses implicates tau as a susceptibility gene for idiopathic PD.

Official Guard and Reserve Manpower Strengths and Statistics: FY 1989 Summary

DTIC Science & Technology

1989-01-01

S0- 5.8 co It0. 0 m a* t7 N 𔃾 in o𔃾 t N o - n-K, 0 mI- IZ 0 N m i an N 0o cm a, . KZK UK 14i N~’ 47 𔃾 N 0’ 0 D- 0 00a, c KlS K K I NNN 7n 𔃾 𔃾 No...W C, 00C0F)a*P m 00 on 0..0.....P00Mlso0 do w .P- 638%1 P 1 KZK ~ ~ P)goMK II- .8 4N i 40. 8 4 I.5M!.4M0󈧣U . * . P) woo- 3. 30 K 30A- N C4 in4C i K

All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 10. Aberdeen, Maryland-Woodbine, Maryland.

DTIC Science & Technology

1987-01-01

NAME OF FUNDING/SPONSORING 8b. OFFICE SYMBOL 9 . PROCUREMENT INSTRUMENT IDENTIFICATION NUMBER ORGANIZATION (If applicable) Bc. ADDRESS (City, State...8217.io 000 0 00 01: 4 ,4.100000000000000000 4 10 20 ZO 000Q cc0 Z0 0 ’ 14 C,4-J0000000000000000000 9 < ɜ "ə 4< "ɜ ".x4 In4 L) 444 0 < -J.0 0 KO:x Z (D...o( .i.- 04M 5- 3I- ap 3- (V) 00) 40 0- 9 ) m .v-C 1I 0 0 0 0 N N N N N N MOO< 1 l -4-4O~ 0.-I -4 0N 0 (.-L4W-4 0-N D -N 0-NI <I v-4- oo- 4- - "- p ᝰ

Dollar Summary of Prime Contract Awards by Contractor, State or Country, and Place. Part 5 (Matthew Electric Supply Co-Quantum Research Inc

DTIC Science & Technology

1990-01-01

t4Ie~ r-)6 f- 016240 C c 6-) 0. N. ’)M 40 0 - < qt U..6 ON’)t V- Mw iS.m MM m M w N M v v n I 6- 06.- I wI td -. -N 6 ma toC’ (G. 0- 0g 00 Z-6- o...Into 064 - WI ’a OW)C’IC 00 CO 0 (0( 0- > ’ 0 4 0 td 00 6 4 00 0-4 0 N-N0 0-L) 6-46 4Z ,L- V6 U. 4 I I- 06 so6 00 00 M0 a( 00 E 6-4~1 >- I-- (0- ow...0L L. 0eC) - ) ~ U 0 1- 09 0) .- 4 N (C-0 U) m<t~ (3 4 ans U 06 LL. c I 4 -4 C’). -4 00- 4a 0L to I.L 4 C - w Co- LL a) C 0 > 4 5r~ 5 >O td - - .. >Ci

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 2. (American Nucleonics Corp.-Beachler Mark Associates)

DTIC Science & Technology

1989-01-01

Inn In -4 MOI -e4.~~3fm >U 6-z a ~ Wz ;w<<* -4.c 00)00 P.U~ 11.0U 22 02A4UZ z222 >Z 2222 02 * 00 U 0.-411)M)00 P. 0) U)n In C0U)M)004 0o RtO P 0)1a L o...z2 22222222zzz B 40 I W) 11 222 2 222 Z 222zz Z zzzzz2ZZZZ 11 1 Com 00n00 IV0) rto 04 l (0-4q O0 ()N04 0 ) I 0(0-4in0)-0000 B- >I woo B 11400) Rt...400o cc00. C X a vs I M-4 N X LU 4 0ULI L.. I.L. g,-4N-41U’I 4 N x 0U 5 cc N .40-4 N 2NGO(0 U-4 <-4 0)4 k ~N00004 (1 X wo Cci *00 IT4000 If .0 I 0-4

Does It Matter Where You Work? A Comparison of How Three Work Venues (Traditional Office, Virtual Office, and Home Office) Influence Aspects of Work and Personal/Family Life.

ERIC Educational Resources Information Center

Hill, E. Jeffrey; Ferris, Maria; Martinson, Vjollca

2003-01-01

A comparison was made of IBM employees in traditional offices (n=4,316), virtual offices (n=767), and home offices (n=441). Home office teleworking helped balance work and family and enhanced business performance with cost savings. Virtual office teleworking was associated with less work-family balance and less successful personal/family life.…

Alpha List of Prime Contract Awards. Oct 91 - Sep 92. FY 92 (Branscome Julius Inc - Chriscott Supply)

DTIC Science & Technology

1993-01-01

821702I0(04o ItIT 4444 9 0 cCNi "NIN 04 (0J a𔃻 47f-f a 1 >,Of enC o<i 020z0 o 0000 N 0)100 43 1)(1C) ’(1)V ý-lIA N! (’l( 0) -4 M LA 0. (-10 4-I I -4 -4...I I enC > N41a r0))00) 4 o mm q 7 40)0 ID)0)(0r-NO4 m0) 0 04( o r- N I m 0"-4-4(1)0) 0(1 4)100 II CDC>00 00 00 00 000t00 0I0to- -4--4-41000 10 11 D0>1...0004 11--4 WO"CN, .- 4 -4 -4.-4 -4IUU 0n C) A-r- M M c ( n00 nU,0) In.-4 W4 it0 1I (00 4 it 0 m ENc --IO <>" ൈ ý 0 0’-441 -4 m F" -4 t NN04C’JO< 1ý- Ul

FAA Air Traffic Activity

DTIC Science & Technology

1992-09-01

d, 0 U 0 E-4- 1-4 p/7. .4 H, , , I I F T 1 1 I1 - - B1 -4 c nI a W I~ 0" Q o6 0G 0 00 24 Q N~nIn 1--- U 00 :C% F’-4 -. 07 ;T4 LIn E1-6 TABLE 1-5 30...0 RUGBY ................................... ........................... ND N ZMP 43 0 0 42 1 RUSHFORD MUNICIPAL ..................... MN N ZMP 1 0 0

All Prime Contract Awards by State or Country, Place, and Contractor. Part 21 (Stafford Virginia-Yellowstone Park)

DTIC Science & Technology

1990-01-01

40000 -loco � 000 00"e00000 a Ir-4 N 4 c 40~C) ,0oe c c C)CV V CV C-i-4 caninannananmwa m wnan W* IC04N4 U Ncv ~f0cv(’)mmma) ’. -4-4-4-4-1 *4NN .0...MC’) U N 40 N C’) Ncv ) 0 -IN ON ON C0 0-44.-I- ON0 : cc 04) U C’) -I 04. OP. NO4.0 0-I N4. I--Cv) Vq44.4..4. 644 m : a 4) -I 00 ao -4.40 M a -40 00...IZ .- JvvvZ IW NCV 8 Nl P.C c’S r 0P r-0 P. P.- 0r 4W5 0>3ON -IN -N OV)N NN O-NN -IN NN OIN ONNNNNNN .8 .c co 04 C4 O( I 04W Nz z z zz z zz z zz z z zz

Joint Test Project Report of Combat Air Support Target Acquisition Program. SEEKVAL. Aided Visual Terrain Table Experiments (IB1). Volume 2.

DTIC Science & Technology

1975-09-01

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Parent–Child Relationships in Stepfather Families and Adolescent Adjustment: A Latent Class Analysis

PubMed Central

Amato, Paul R.; King, Valarie; Thorsen, Maggie L.

2015-01-01

In the current study the authors drew on Waves I and III from Add Health to examine the closeness of parent–adolescent relationships in married mother–stepfather families (N = 1,934). They used latent class analysis to identify family constellations defined by adolescents’ relationships with all of their parents: mothers, stepfathers, and biological nonresident fathers. In particular, the authors (a) identified the most common underlying patterns of adolescent–parent relationships in stepfamilies; (b) determined the background characteristics that predict membership in these groups; and (c) examined how adolescents in these groups fare with respect to depressive symptoms, delinquency, and substance use. The results indicate that adolescents’ relationships can be represented with 4 latent classes. Adolescents in these classes differ on measures of adjustment, and many of these differences persist into the early adult years. PMID:27022199

All Prime Contract Awards by State or Country, Place, and Contractor, FY 85. Part 18 (Addison, Vermont - Wytheville, Virginia).

DTIC Science & Technology

1985-01-01

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All Prime Contract Awards by State or Country, Place, and Contractor. Part 17 (Abbeville S. Carolina-Eldorado Texas)

DTIC Science & Technology

1990-01-01

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POROUS ALUMINOPHOSPHATES :From Molecular Sieves to Designed Acid Catalysts

NASA Astrophysics Data System (ADS)

Pastore, H. O.; Coluccia, S.; Marchese, L.

2005-08-01

This review covers the synthesis, characterization, and physico-chemical properties of microporous and mesoporous aluminophosphates and silicoaluminophosphates molecular sieves. Particular emphasis is given to the materials that have found applications as acid catalysts. We consider the evolution of the synthesis procedures from the first discoveries to the current methodologies and give perspectives for new possible synthesis strategies. Emphasis is given to the use of specially prepared precursors/reactants designed for the use as molecular sieves. Experimental (especially MAS-NMR and FTIR spectroscopy) and theoretical approaches to the description of the Si insertion into the ALPO framework and to the acidic properties of SAPOs and MeAPSOs materials are discussed.

Overground Excess Sound Attenuation (ESA). Volume 1. Experimental Study for Flat Grassy Terrains.

DTIC Science & Technology

1987-06-01

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Development and Validation of Quality Criteria for Providing Patient- and Family-centered Injury Care.

PubMed

Boyd, Jamie M; Burton, Rachael; Butler, Barb L; Dyer, Dianne; Evans, David C; Felteau, Melissa; Gruen, Russell L; Jaffe, Kenneth M; Kortbeek, John; Lang, Eddy; Lougheed, Val; Moore, Lynne; Narciso, Michelle; Oxland, Peter; Rivara, Frederick P; Roberts, Derek; Sarakbi, Diana; Vine, Karen; Stelfox, Henry T

2017-08-01

The aim of this study was to develop and evaluate the content validity of quality criteria for providing patient- and family-centered injury care. Quality criteria have been developed for clinical injury care, but not patient- and family-centered injury care. Using a modified Research AND Development Corporation (RAND)/University of California, Los Angeles (UCLA) Appropriateness Methodology, a panel of 16 patients, family members, injury and quality of care experts serially rated and revised criteria for patient- and family-centered injury care identified from patient and family focus groups. The criteria were then sent to 384 verified trauma centers in the United States, Canada, Australia, and New Zealand for evaluation. A total of 46 criteria were rated and revised by the panel over 4 rounds of review producing 14 criteria related to clinical care (n = 4; transitions of care, pain management, patient safety, provider competence), communication (n = 3; information for patients/families; communication of discharge plans to patients/families, communication between hospital and community providers), holistic care (n = 4; patient hygiene, kindness and respect, family access to patient, social and spiritual support) and end-of-life care (n = 3; decision making, end-of-life care, family follow-up). Medical directors, managers, or coordinators representing 254 trauma centers (66% response rate) rated 12 criteria to be important (95% of responses) for patient- and family-centered injury care. Fewer centers rated family access to the patient (80%) and family follow-up after patient death (65%) to be important criteria. Fourteen-candidate quality criteria for patient- and family-centered injury care were developed and shown to have content validity. These may be used to guide quality improvement practices.

CHALLENGES OF DSD: DIVERSE PERCEPTIONS ACROSS STAKEHOLDERS

PubMed Central

Kogan, Barry A.; Gardner, Melissa; Alpern, Adrianne N.; Cohen, Laura M.; Grimley, Mary Beth; Quittner, Alexandra L.; Sandberg, David E.

2012-01-01

Background/Aims Disorders of Sex Development (DSD) are congenital conditions in which chromosomal, gonadal, or anatomic sex development is atypical. Optimal management is patient- and family-centered and delivered by interdisciplinary teams. The present pilot study elicits concerns held by important stakeholders on issues affecting young patients with DSD and their families. Methods Content from focus groups with expert clinicians (pediatric urologists [n=7], pediatric endocrinologists [n=10], mental health professionals [n=4]), DSD patient advocates (n=4), and interviews with parents of DSD-affected children (newborn to 6 yrs; n=11) was coded and content-analyzed to identify health-related quality of life issues. Results Key stressors varied across stakeholder groups. In general, family-centered issues were noted more than child-centered. In the child-centered domain, providers worried more about physical functioning; family and advocates emphasized gender concerns and body image. In the family-centered domain, parental concerns about medication management outweighed those of providers. Advocates reported more stressors regarding communication/information than other stakeholders. Conclusion Variability exists across stakeholder groups in the key concerns affecting young children/families with DSD. Interdisciplinary DSD healthcare team development should account for varying perspectives when counseling families and planning treatment. PMID:22832323

REMBASS Commandability. Trade Off Analysis (TOA)/Trade Off Determination (TOD)

DTIC Science & Technology

1977-12-15

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Family learning: the missing exemplar

NASA Astrophysics Data System (ADS)

Dentzau, Michael W.

2013-06-01

As a supporter of informal and alternative learning environments for science learning I am pleased to add to the discussion generated by Adriana Briseño-Garzón's article, "More than science: family learning in a Mexican science museum". I am keenly aware of the value of active family involvement in education in general, and science education in particular, and the portrait provided from a Mexican science museum adds to the literature of informal education through a specific sociocultural lens. I add, however, that while acknowledging the powerful the role of family in Latin American culture, the issue transcends these confines and is instead a cross-cutting topic within education as a whole. I also discuss the ease at which in an effort to call attention to cultural differences one can, by the very act, unintentionally marginalize others.

All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 5. Air Force Academy, Colorado-Wilmington, Delaware.

DTIC Science & Technology

1987-01-01

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How Are Self-Efficacy and Family Involvement Associated with Less Sexual Risk Taking among Ethnic Minority Adolescents?

ERIC Educational Resources Information Center

Van Campen, Kali S.; Romero, Andrea J.

2012-01-01

The current study investigates the protective influences of family involvement (i.e., parental monitoring, communication, closeness, and family proximity) and sexual self-efficacy on the risky sexual behavior of ethnic minority (predominantly Mexican-origin) adolescents in the southwestern United States (N = 122). Results indicate that whereas…

Prime Contract Awards Over $25,000 by Major System, Contractor and State Part 2 (AVG NAVY-SMR NAVY)

DTIC Science & Technology

1990-01-01

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All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 4. Sage Hen, California-Yolo, California.

DTIC Science & Technology

1987-01-01

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Family structure and risk behaviors: the role of the family meal in assessing likelihood of adolescent risk behaviors.

PubMed

Goldfarb, Samantha; Tarver, Will L; Sen, Bisakha

2014-01-01

Previous literature has asserted that family meals are a key protective factor for certain adolescent risk behaviors. It is suggested that the frequency of eating with the family is associated with better psychological well-being and a lower risk of substance use and delinquency. However, it is unclear whether there is evidence of causal links between family meals and adolescent health-risk behaviors. The purpose of this article is to review the empirical literature on family meals and adolescent health behaviors and outcomes in the US. A SEARCH WAS CONDUCTED IN FOUR ACADEMIC DATABASES: Social Sciences Full Text, Sociological Abstracts, PsycINFO®, and PubMed/MEDLINE. We included studies that quantitatively estimated the relationship between family meals and health-risk behaviors. Data were extracted on study sample, study design, family meal measurement, outcomes, empirical methods, findings, and major issues. Fourteen studies met the inclusion criteria for the review that measured the relationship between frequent family meals and various risk-behavior outcomes. The outcomes considered by most studies were alcohol use (n=10), tobacco use (n=9), and marijuana use (n=6). Other outcomes included sexual activity (n=2); depression, suicidal ideation, and suicide attempts (n=4); violence and delinquency (n=4); school-related issues (n=2); and well-being (n=5). The associations between family meals and the outcomes of interest were most likely to be statistically significant in unadjusted models or models controlling for basic family characteristics. Associations were less likely to be statistically significant when other measures of family connectedness were included. Relatively few analyses used sophisticated empirical techniques available to control for confounders in secondary data. More research is required to establish whether or not the relationship between family dinners and risky adolescent behaviors is an artifact of underlying confounders. We recommend that researchers make more frequent use of sophisticated methods to reduce the problem of confounders in secondary data, and that the scope of adolescent problem behaviors also be further widened.

Official Guard and Reserve Manpower Strengths and Statistics, FY 1985 Summary

DTIC Science & Technology

1985-01-01

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Increased Pre- and Early-Adolescent Stress in Youth with a Family History of Substance Use Disorder and Early Substance Use Initiation.

PubMed

Charles, Nora E; Mathias, Charles W; Acheson, Ashley; Bray, Bethany C; Ryan, Stacy R; Lake, Sarah L; Liang, Yuanyuan; Dougherty, Donald M

2015-10-01

Individuals with a family history of substance use disorders (Family History Positive) are more likely to have early-onset substance use (i.e., prior to age 15), which may contribute to their higher rates of substance use disorders. One factor that may differentiate Family History Positive youth who engage in early-onset substance use from other Family History Positive youth is exposure to stressors. The aim of this study was to quantify how exposure to stressors from age 11-15 varies as a function of family history of substance use disorders and early-onset substance use. Self-reported stressors were prospectively compared in a sample of predominately (78.9%) Hispanic youth that included 68 Family History Positive youth (50% female) who initiated substance use by age 15 and demographically matched non-users with (n = 136; 52.9% female) and without (n = 75; 54.7% female) family histories of substance use disorders. Stressors were assessed at 6-month intervals for up to 4 years. Both the severity of stressors and the degree to which stressors were caused by an individual's own behavior were evaluated. All three groups differed from one another in overall exposure to stressors and rates of increase in stressors over time, with Family History Positive youth who engaged in early-onset substance use reporting the greatest exposure to stressors. Group differences were more pronounced for stressors caused by the participants' behavior. Family History Positive users had higher cumulative severity of stressors of this type, both overall and across time. These results indicate greater exposure to stressors among Family History Positive youth with early-onset substance use, and suggest that higher rates of behavior-dependent stressors may be particularly related to early-onset use.

Increased Pre- and Early-Adolescent Stress in Youth with a Family History of Substance Use Disorder and Early Substance Use Initiation

PubMed Central

Charles, Nora E.; Mathias, Charles W.; Acheson, Ashley; Bray, Bethany C.; Ryan, Stacy R.; Lake, Sarah L.; Liang, Yuanyuan; Dougherty, Donald M.

2015-01-01

Individuals with a family history of substance use disorders (Family History Positive) are more likely to have early-onset substance use (i.e., prior to age 15), which may contribute to their higher rates of substance use disorders. One factor that may differentiate Family History Positive youth who engage in early-onset substance use from other Family History Positive youth is exposure to stressors. The aim of this study was to quantify how exposure to stressors from age 11 to 15 varies as a function of family history of substance use disorders and early-onset substance use. Self-reported stressors were prospectively compared in a sample of predominately (78.9%) Hispanic youth that included 68 Family History Positive youth (50% female) who initiated substance use by age 15 and demographically matched non-users with (n=136; 52.9% female) and without (n=75; 54.7% female) family histories of substance use disorders. Stressors were assessed at 6-month intervals for up to 4 years. Both the severity of stressors and the degree to which stressors were caused by an individual’s own behavior were evaluated. All three groups differed from one another in overall exposure to stressors and rates of increase in stressors over time, with Family History Positive youth who engaged in early-onset substance use reporting the greatest exposure to stressors. Group differences were more pronounced for stressors caused by the participants’ behavior. Family History Positive users had higher cumulative severity of stressors of this type, both overall and across time. These results indicate greater exposure to stressors among Family History Positive youth with early-onset substance use, and suggest that higher rates of behavior-dependent stressors may be particularly related to early-onset use. PMID:25788123

Tinker AFB, Oklahoma City, Oklahoma. Revised Uniform Summary of Surface Weather Observations (RUSSWO)

DTIC Science & Technology

1975-06-11

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AGARD (Advisory Group for Aerospace Research and Development) Guide to Aerospace and Defence Technical Report Series in NATO Countries.

DTIC Science & Technology

1987-05-01

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Training Extract AFSC 791X0 Public Affairs.

DTIC Science & Technology

1985-09-01

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Subcontracting Opportunities with DoD Major Prime Contractors

DTIC Science & Technology

1991-01-01

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Department of the Navy FY 1994 Budget Estimates. Military Personnel, Navy. Justification of Estimates Submitted to Congress April 1993

DTIC Science & Technology

1993-04-01

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Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 8 (Electronic Design Inc-Florida North Shipyards)

DTIC Science & Technology

1990-01-01

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Inorganic Reactants for Synthesis of Novel Fluorocarbon Derivatives.

DTIC Science & Technology

1980-05-13

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Evaluation of EMP/EMI Requirements versus Corrosion Prevention Methods

DTIC Science & Technology

1992-10-07

TO 1-1-1, Cleaning of Aerospace Equipment. (Basic Issue. 29 Jun 79, Change 18, 3 Sep 87). b. TO 1-1-2, Corrosion Prevention and Control by Aerospace...n% 414) 1413 4- 0 CC ,r to > u I >V 41-41q41" 41 O1 0O4) 1 E Lfl 4) ... JJ ( E-4 I- I4 S- 4r4zzu V z m 0 : 29 Table 5. Location of Test Areas on E-3...Nm " -x -! r •i A26 I NIN II I~ w- cA27 I I I II i -N .3O Is I/n A280 mU < I 1) I __ _ __ A28 I I I < 0 N w I I I Ti NA III

Prime Contract Awards Alphabetically by Contractor, State or Country, and Place. Part 11 (Lemmon Company, Sellersville Pennsylvania - McEwen Construction, Beale AFB, California), FY1991

DTIC Science & Technology

1991-01-01

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Heterometallic cerium(IV) perrhenate, permanganate, and molybdate complexes supported by the imidodiphosphinate ligand [N(i-Pr2PO)2]-.

PubMed

Wang, Guo-Cang; Sung, Herman H Y; Dai, Feng-Rong; Chiu, Wai-Hang; Wong, Wai-Yeung; Williams, Ian D; Leung, Wa-Hung

2013-03-04

Heterometallic cerium(IV) perrhenate, permanganate, and molybdate complexes containing the imidodiphosphinate ligand [N(i-Pr2PO)2](-) have been synthesized, and their reactivity was investigated. Treatment of Ce[N(i-Pr2PO)2]3Cl (1) with AgMO4 (M = Re, Mn) afforded Ce[N(i-Pr2PO)2]3(ReO4) (2) or Ce2[N(i-Pr2PO)2]6(MnO4)2 (3). In the solid state, 3 is composed of a [Ce2{N(i-Pr2PO)2}6(MnO4)](+) moiety featuring a weak Ce-OMn interaction [Ce-OMn distance = 2.528(8) Å] and a noncoordinating MnO4(-) counteranion. While 3 is stable in the solid state and acetonitrile solution, it decomposes readily in other organic solvents, such as CH2Cl2. 3 can oxidize ethylbenzene to acetophenone at room temperature. Treatment of 1 with AgBF4, followed by reaction with [n-Bu4N]2[MoO4], afforded [Ce{N(i-Pr2PO)2}3]2(μ-MoO4) (4). Reaction of trans-Ce[N(i-Pr2PO)2]2(NO3)2 (5), which was prepared from (NH4)2Ce(NO3)6 and K[N(i-Pr2PO)2], with 2 equiv of [n-Bu4N][Cp*MoO3] yielded trans-Ce[N(i-Pr2PO)2]2(Cp*MoO3)2 (6). 4 can catalyze the oxidation of methyl phenyl sulfide with tert-butyl hydroperoxide with high selectivity. The crystal structures of complexes 3-6 have been determined.

Enhancement and Bandwidth Compression of Noisy Speech by Estimation of Speech and Its Model Parameters

DTIC Science & Technology

1978-08-01

110 V.4.1 Motivation for the Revision 110 V.4.2 Estimation of s(i)’s(j) by E[s(i) s(j) la ,v 111 V.4.3 RLMAP Estimation Procedure 114 V.5 Extension to...and .ne distinction will be left to the context in which it is used. -83- P(Sola,g,si) = p~s(N-1,0) la ,g,s(-!,-p)) N-i = i p (s (n) Ia,g, s(n-1, -p...s(n) la ,g,s(n-!,n-p)) - 1 (si) T 2 2 exp[- -I- (s(n)-a *s(n-1,n-p)) (4-5) (2"rg /2g From equations (4-4) and (4-5), a 1 NI T 2 (Ig ) 22 N/Iexp

The AFGL Four Color Infrared Sky Survey: Catalog of Observations at 4. 2, 11.0, 19.8 and 27.4 micrometers

DTIC Science & Technology

1976-09-17

m 0 La ro - - -- - - - - -NNý ý7- miC4’ to in Uve 0 11Nmm 1 v m rvv 0I " m0 -in mC4-- m ko So int 0i~ m1 Li fnMf 4090WMT -N M M G T w m m O O t nvi...Woi’CDr’ nq:;; IT0 C -1-4400 4 l1 1 in L v00N’I0qI W10𔃺(IN 010 n 0(to 0 g NNr m O~ InI 01’ N C a M0 N014n r(N TOi~ni~i N ChIT n0n N m v0 W0101 N

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mebarki, F.; Forest, M.G.; Josso, N.

The androgen insensivity syndrome (AIS) is a recessive X-linked disorder resulting from a deficient function of the androgen receptor (AR). The human AR gene has 3 functional domains: N-terminal encoded by exon 1, DNA-binding domain encoded by exons 2 and 3, and androgen-binding domain encoded by exons 4 to 8. In order to characterize the molecular defects of the AR gene in AIS, the entire coding regions and the intronic bording sequences of the AR gene were amplified by PCR before automatic direct sequencing in 45 patients. Twenty seven different point mutations were found in 32 unrelated AIS patients: 18more » with a complete form (CAIS), 14 with a partial form (PAIS); 18 of these mutations are novel mutations, not published to date. Only 3 mutations were repeatedly found: R804H in 3 families; M780I in 3 families and R774C in 2 families. For 26 patients out of the 32 found to have a mutation, maternal DNA was collected and sequenced: 6 de novo mutations were detected (i.e. 23% of the cases). Finally, no mutation was detected in 13 patients (29%): 7 with CAIS and 6 familial severe PAIS. The latter all presented with perineal hypospadias, micropenis, 4 out of 6 being raised as girl. Diagnosis of AIS in these 13 families in whom no mutation was detected is supported by the following criteria: clinical data, familial history (2 or 3 index cases in the same family), familial segregation of the polymorphic CAG repeat of the AR gene. Mutations in intronic regions or the promoter of the AR gene could not explain all cases of AIS without mutations in the AR coding regions, because AR binding (performed in 9 out of 13) was normal in 6, suggesting the synthesis of an AR protein. This situation led us to speculate that another X-linked factor associated with the AR could be implicated in some cases of AIS.« less

Progression along the Bipolar Spectrum: A Longitudinal Study of Predictors of Conversion from Bipolar Spectrum Conditions to Bipolar I and II Disorders

PubMed Central

Alloy, Lauren B.; Urošević, Snežana; Abramson, Lyn Y.; Jager-Hyman, Shari; Nusslock, Robin; Whitehouse, Wayne G.; Hogan, Michael

2011-01-01

Little longitudinal research has examined progression to more severe bipolar disorders in individuals with “soft” bipolar spectrum conditions. We examine rates and predictors of progression to bipolar I and II diagnoses in a non-patient sample of college-age participants (n = 201) with high General Behavior Inventory scores and childhood or adolescent onset of “soft” bipolar spectrum disorders followed longitudinally for 4.5 years from the Longitudinal Investigation of Bipolar Spectrum (LIBS) project. Of 57 individuals with initial cyclothymia or bipolar disorder not otherwise specified (BiNOS) diagnoses, 42.1% progressed to a bipolar II diagnosis and 10.5% progressed to a bipolar I diagnosis. Of 144 individuals with initial bipolar II diagnoses, 17.4% progressed to a bipolar I diagnosis. Consistent with hypotheses derived from the clinical literature and the Behavioral Approach System (BAS) model of bipolar disorder, and controlling for relevant variables (length of follow-up, initial depressive and hypomanic symptoms, treatment-seeking, and family history), high BAS sensitivity (especially BAS Fun Seeking) predicted a greater likelihood of progression to bipolar II disorder, whereas early age of onset and high impulsivity predicted a greater likelihood of progression to bipolar I (high BAS sensitivity and Fun-Seeking also predicted progression to bipolar I when family history was not controlled). The interaction of high BAS and high Behavioral Inhibition System (BIS) sensitivities also predicted greater likelihood of progression to bipolar I. We discuss implications of the findings for the bipolar spectrum concept, the BAS model of bipolar disorder, and early intervention efforts. PMID:21668080

All Prime Contract Awards by State or Country, Place, and Contractor, FY 88. Part 1. (Aliceville, Alabama-Sevier, Arkansas).

DTIC Science & Technology

1988-01-01

W0(D1- 4V444-t * 400O-4 1 X:00P-- (01 - r-r- Z 30 I- L 0U) uU)z 04 * Wu n ) enC ’)4 z 00002 IN-4I0o--q I (DUU 4ni 0000 0N 4 < WOOOOO 0 X:0 2000 -.4...0 o04ɘ c) I 4NN 0)N 00 - NNrN r- "C4TN)C C4 LAN (IN rN (N- 0) r4 W I DCI) ’(00 000 0000 oco lADO (00 LAO 4 0 0O 0)0 Ln CO OIDC 1 O n IM< L < 0"-<ɘ...0 - a0 C-) 11000 ’t4 LADO f-O 0 <am IINLA 3 r U-0- - ( w< <- n(00l NLA (𔃺(<N< 00N7 O <OC <-LLA 0 140" I CI) (0 LA Ln -O.40 ) Ln- L a0 0Y) D(0

Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (1079 Construction Corp - American Technology Corp.). Part 1

DTIC Science & Technology

1994-03-01

4 YuN0 H CJa- La.0Lm La. 00 0 00oa 0 0 0000 0 N 0’a-4 cy 4 00 0 00 0 0 0000 0 0ON 4 m6U CIO acca anaH )N P. P 0 v N N Nn N CaM i0 111191 CA In S as...P 1 0t In’n’’n’’nl" fI4)4)Il" ffM f Nf I1co0(Go11 0, =.4 NN o0 x- 0 <ý 0C’)V I-In 40 (0 444 4444t444 44444L 0.. 1’ (00e 11 -4L >.. ItJN I-4 4) 1-4 to4

Distribution of Gene Mutations Associated with Familial Normosmic Idiopathic Hypogonadotropic Hypogonadism

PubMed Central

Gürbüz, Fatih; Kotan, L. Damla; Mengen, Eda; Şıklar, Zeynep; Berberoğlu, Merih; Dökmetaş, Sebila; Kılıçlı, Mehmet Fatih; Güven, Ayla; Kirel, Birgül; Saka, Nurçin; Poyrazoğlu, Şükran; Cesur, Yaşar; Doğan, Murat; Özen, Samim; Özbek, Mehmet Nuri; Demirbilek, Hüseyin; Kekil, M. Burcu; Temiz, Fatih; Önenli Mungan, Neslihan; Yüksel, Bilgin; Topaloğlu, Ali Kemal

2012-01-01

Objective: Normosmic idiopathic hypogonadotropic hypogonadism (nIHH) is characterized by failure of initiation or maintenance of puberty due to insufficient gonadotropin release, which is not associated with anosmia/hyposmia. The objective of this study was to determine the distribution of causative mutations in a hereditary form of nIHH. Methods: In this prospective collaborative study, 22 families with more than one affected individual (i.e. multiplex families) with nIHH were recruited and screened for genes known or suspected to be strong candidates for nIHH. Results: Mutations were identified in five genes (GNRHR, TACR3, TAC3, KISS1R, and KISS1) in 77% of families with autosomal recessively inherited nIHH. GNRHR and TACR3 mutations were the most common two causative mutations occurring with about equal frequency. Conclusions: Mutations in these five genes account for about three quarters of the causative mutations in nIHH families with more than one affected individual. This frequency is significantly greater than the previously reported rates in all inclusive (familial plus sporadic) cohorts. GNRHR and TACR3 should be the first two genes to be screened for diagnostic purposes. Identification of causative mutations in the remaining families will shed light on the regulation of puberty. Conflict of interest:None declared. PMID:22766261

Secretory overexpression and isotopic labeling of the chimeric relaxin family peptide R3/I5 in Pichia pastoris.

PubMed

Guo, Yu-Qi; Wu, Qing-Ping; Shao, Xiao-Xia; Shen, Ting; Liu, Ya-Li; Xu, Zeng-Guang; Guo, Zhan-Yun

2015-06-01

Relaxin family peptides are a group of peptide hormones with divergent biological functions. Mature relaxin family peptides are typically composed of two polypeptide chains with three disulfide linkages, rendering their preparation a challenging task. In the present study, we established an efficient approach for preparation of the chimeric relaxin family peptide R3/I5 through secretory overexpression in Pichia pastoris and in vitro enzymatic maturation. A designed single-chain R3/I5 precursor containing the B-chain of human relaxin-3 and the A-chain of human INSL5 was overexpressed in PichiaPink strain 1 by high-density fermentation in a two-liter fermenter, and approximately 200 mg of purified precursor was obtained from one liter of the fermentation supernatant. We also developed an economical approach for preparation of the uniformly (15)N-labeled R3/I5 precursor by culturing in shaking flasks, and approximately 15 mg of purified (15)N-labeled precursor was obtained from one liter of the culture supernatant. After purification by cation ion-exchange chromatography and reverse-phase high performance liquid chromatography, the R3/I5 precursor was converted to the mature two-chain form by sequential treatment with endoproteinase Lys-C and carboxypeptidase B. The mature R3/I5 peptide had an α-helix-dominated conformation and retained full receptor-binding and receptor activation activities. Thus, Pichia overexpression was an efficient approach for sample preparation and isotopic labeling of the chimeric R3/I5 peptide. This approach could also be extended to the preparation of other relaxin family peptides in future studies.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1987. Part 11. Kodet Architectural Group-Mantech Field Engineering.

DTIC Science & Technology

1987-01-01

8217’ C4J C >)> Cm (0 C’) C- ir40 0 -4-4N (4 0 0 .- .>’ .- . ~ - - C 4NL.4- N04.. (0 M’) C -00)0 N U C -(D tD C ,’ m0 0- r, O N N 0 V I- CNFL O4 .0 U 0...10 0646I 0- -I WN 0 Z-D0 I-C’ C-C’) 01 O 6-0 C’)’ C’) 0 ’-40 0l11 0 0 CD C’)U CC C ) TD N0l 06 N- 0.60 00 00000 on 00 0, C. C 000 00 00 000) _𔃺 -’l) U...W LJ "- C C :34 N m4 1 0 w 4 n-it un w N nN r, v 3- 4bD )n0wt400 040 cCO 0n 00 V cl 00a) C)O0LA m-4 I4 N 0413 4 VMPP,?-0V VN 4 (D W 04 4O(D0) 00 cc -4

Prime Contract Awards by State or Country, Place and Contractor. Part 2 (Murfreesboro, Arkansas - Livermore, California), FY1991

DTIC Science & Technology

1991-01-01

0 01 01010 01 CD01 00 01 010 0 < % 5 N0 I 0000 H 01 01 0 0 --00-4 -4 C> 0 -00. 00 o %00 10 %- I 0000...I’-001t- 0 -4 00 0 K I0Mon If N4 -4-IC’-I 0P 5 1 0 4NN C4 I <-4 "iM’)-4 -4 M 04 004JNN-4N-4 -4 -4-4 cc Ks I 0 (i on It 00 IC’)o0 W W0 Oc’-4NS C 0 ...it 1-- - Oil 00000000 -4 -4 -- 0 ) ()00) 0 - S -4 o 5 (-N IS 0001 . o C 0 000 0 0 0 100C,00 0

All Prime Contract Awards by State or Country, Place and Contractor. Part 3. (Lemon Grove, California-San Bruno, California)

DTIC Science & Technology

1989-01-01

NNJ Ql B 0- 4yo if 0(( 4 I 0. -4 (71 11 I 0-400M1U c) M-0(1 0 00c 0 0> 0 00 00Q 00 000 Q II -40041 0> 00 0 0> 0 00 c 00 00 00 0 0 O--1NA it N NNP, N N...a oil I Cc01 l4 4 02 I-4 4 04 wt l i 4V oil I -4cO’ it 0 co n 4. N -4 Qs 0 00 m 0r 4Yo -,C4-ti 0J11 41(< m 1100-4 4a’ C-000 - ON0 (1-0 * 0 -4 4(0 C4

Mean Conditions and Turbulence Statistics at Vandenberg AFB, California,

DTIC Science & Technology

1984-11-01

2NN M N NN ’CN N NN N4 I’~tJN NN NIJN I pIi JN’ W’N NCJ’ ViNNCJ m I’N’(I N’N CJ N N N C’ 0 ’o CD22 REPRODUCEDU AT CG0VFRr4?A.FJ1 uvrF 11.4 PiJ0t’ N

Alternate Implosion Models for the Plane Parallel Diode.

DTIC Science & Technology

1982-04-02

higher density regions, perhaps altering the spectral mix of line and continuum radiation. 3) Examine the effect of the chemical potential (properly...inclusion of previous time levels (i-i, i-2...) in an estimate of AF would be a means of filtering the noise that might develop in this variable, and...NN’N NO G~l-0NNV . OO’)N aQ.’)4Ŕ N 4 . * .~ 0 I’) MMIs )NN4 P).N 44 NN 4 0. 00(0 0-0 NN 1 OWEI) ~4N Vi N 0 vm -N 0. 0N0 M a 40 0 I.) 0.0. N Nflmwo ONNOM

Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Martinez Architects Inc. - Nihon Boshoku Kogyo KK)

DTIC Science & Technology

1994-03-01

0 0 .-4 -4 -’.-4 00 00 0 00 0 0 0 0 0 0 00 0 0 0 u If C 1 00Of I 11-NW CV) CV) NoNm N NC~ f qCqC f V)m()C O n( CV)’C) enC’ m’ Of m C") Oil I O C0...1 C Y)im mn c )0)()o 0 mmmmmfmmmmmmmmmmm om m) Of mY )1)O )C)CY 7 Y f 11 C I 0 W 110 If I nc-N 11LU) 00 (n If I CO N i’l11- < Go Co- oil I toON w I...0ý-4-4.-00 0 0 0 0 4.4.4.4000000000 UII1 lCo l II MlNN1 meym N C Cl MCl C.) NN N l(14~llll~~ Oil I cool II-..001001000 (T) 01) 01 01 01

Projections of Demand for Waterborne Transportation, Ohio River Basin, 1980, 1990, 2000, 2020, 2040. Volume 11. Group IX. Feed and Food Products, NEC.

DTIC Science & Technology

1980-12-01

9HIORIVER BASIN 198p, 199, N40, 2029. Prepared for U.S. ARMY CORPS OF ENGINEERS OHIO RIVER DIVISO, HUNTINGTON DISTRICT Contract N DAcW69:78136 by Robert...m c w a 0 %0 -. r, 0 *.. m 0 m 0 0 MI 0% 0 %Dr- 00 HN 0 V4 1 0 I I a, ID %D m .0 4 o 𔃺w0 -Wl N -W 0 H M 0 40 W4 0 N 0 10 0 : C!o 9 11 Ni C!0.-I 0 9...9 ox 0) ON V; .1 C4 .11 at w -I 0 o 4J 0n In ~ Hn In 0CO0 . . 0 4 0 40 0 i 0 0 0D -I 4 14 N N 0’ m 0 40r- N .,I U, mZ 4 0 0 004 H N0 000 CW 0 00 O a

All Prime Contract Awards by State or Country, Place and Contractor. Part 11. (Aitkin, Minnesota-Zephyr Cove, Nevada)

DTIC Science & Technology

1989-01-01

0 )N 41 nuuu~f~01Xflininu33x33:33330I- ( 5 0 CL L . CL.CL 0ilto1 0 N 11000000000000000000000011 2 0 ) 0 ) 0 ) 0 ) 0 ) 011Z2 I00N 11 z00 000000 0000...4 4 4 4 4 4 44 IIC1 ( 0 -NOI 5 )(~ )) C)’C1: 00c ’ I 0 00 000M 00 0 0 0 00 0 0 0 0 I.I < 0 -~l 0 - 00 00 00 0000000000000000000L.I.. WU-I A 40-eN Ii~ mj X00...I m N 1(A) 04 ɜ a I-I -. Z .8 - --. 1-1 - 1--.1-.1-

Amino acid based MOFs: synthesis, structure, single crystal to single crystal transformation, magnetic and related studies in a family of cobalt and nickel aminoisophthales.

PubMed

Sarma, Debajit; Ramanujachary, K V; Lofland, S E; Magdaleno, Travis; Natarajan, Srinivasan

2009-12-21

Four new 5-aminoisophthalates of cobalt and nickel have been prepared employing hydro/solvothermal methods: [Co(2)(C(8)H(5)NO(4))(2)(C(4)H(4)N(2))(H(2)O)(2)].3H(2)O (I), [Ni(2)(C(8)H(5)NO(4))(2)(C(4)H(4)N(2))(H(2)O)(2)].3H(2)O (II), [Co(2)(H(2)O)(mu(3)-OH)(2)(C(8)H(5)NO(4))] (III), and [Ni(2)(H(2)O)(mu(3)-OH)(2)(C(8)H(5)NO(4))] (IV). Compounds I and II are isostructural, having anion-deficient CdCl(2) related layers bridged by a pyrazine ligand, giving rise to a bilayer arrangement. Compounds III and IV have one-dimensional M-O(H)-M chains connected by the 5-aminoisophthalate units forming a three-dimensional structure. The coordinated as well as the lattice water molecules of I and II could be removed and inserted by simple heating-cooling cycles under the atmospheric conditions. The removal of the coordinated water molecule is accompanied by changes in the coordination environment around the M(2+) (M = Co, Ni) and color of the samples (purple to blue, Co; green to dark yellow, Ni). This change has been examined by a variety of techniques that include in situ single crystal to single crystal transformation studies and in situ IR and UV-vis spectroscopic studies. Magnetic studies indicate antiferromagnetic behavior in I and II, a field-induced magnetism in III, and a canted antiferromagnetic behavior in IV.

Department of the Navy Justification of Estimates FY 1992/FY 1992 Budget Estimates Submitted to Congress February 1991, Operation and Maintenance, Navy. Book 2.

DTIC Science & Technology

1991-02-01

LLI LALI IU - >~ -j w -. .. z ., . Iz - m < LLLI LL . 1 -j 01L oo= CC 0 z U.. 14) rowLI w a UmU..0 961V 9ZV--I e0ohozi in 1 01 1 00,01r0...n.&...en e...0 N . 0n a. f. O aj,, 0 t i..a n 4It . en *.i ci I! 1 .e r: 1di.. 0C-cr40 n t110 Il -o mni. -W w 42 n~r 0,’. nir w 𔃺 U 01 10 000000 0 - n 0.c in-e ..4...i in M -i I’i -4. Nt oia 011 0 0 0 0 1 4 I n ,e O 0 0 0 0 0 = 0 O10e e00 0.00 1 0 .. ..00 1 10 0, n 0 0 0 r aeiei..i1er in 10Non N-n0..4, 0010 z n

Solid state coordination chemistry: structural consequences of variations in tether length in the oxovanadium-copper-bisterpy-[O3P(CH2)nPO3]4- system, n= 1-6 (bisterpy = 2,2':4',4'':2'',2'''-quarterpyridyl-6',6''-di-2-pyridine).

PubMed

Ouellette, Wayne; Koo, Bon-Kweon; Burkholder, Eric; Golub, Vladimir; O'Connor, C J; Zubieta, Jon

2004-05-21

Hydrothermal reactions of Na3VO4, an appropriate Cu(II) source, bisterpy and an organodiphosphonate, H2O3P(CH2)nPO3H2 (n = 1-6) yielded a family of materials of the type [Cu2(bisterpy)]4+/VxOy(n-)/[O3P(CH2)nPO3]4-. This family of bimetallic oxides is characterized by an unusual structural diversity. The oxides [[Cu2(bisterpy)]V2O4[O3PCH2PO3H]2] (1), [[Cu2(bisterpy)(H2O)]VO2[O3P(CH2)3PO3][HO3P(CH2)3PO3H2

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 5. (Comtech Microwave Corp.-DOB Corporation)

DTIC Science & Technology

1989-01-01

8217)N1-orn-4 04-4.-4 on 0 (D c’)N"U) N CV3 If1. I moo0 If 0o c) 4N ( 4 -4 .4 -40 -4Nci-4 -414) 003a4a1 moo If Nn -4 >3 100 Coc 1’) -4,1 a01)0 t mo 4 0)N...Col01ə ’ IfN 1.- 0 r,0 a - 0 1" 0 4 0NC14 M M 40000o r-NjN I,_-4 " 411.I’ 14 iI 400fto 1 0 140 10 4000 10000 ol 100 1 t I-N a 401<-4 110) (0 00 00 10...1-1-1-1-1-1-1- . 1- j-1-1-1 - . . -j -. 0 )JJ . J. 1 . . . . j . met M)-4 44 000 a 0 0 0 0 0 0 0 0 00 0 0 0 0 0 0 0 0 C.4 If ( 44< 100 00 00 -j4 of

All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 9. Abilene, Kansas-Yarmouth, Maine.

DTIC Science & Technology

1987-01-01

8217) 00) 00() W-4 4I 0C04 I CNNeNN".40 c.-4 c N C-4 cO -.4-40 C.40(co0~ C(O C.-4 C.4 C-4 I 00 I C-.4-4" "N 4c c .4 CN C O c ENc C-4-4< C.4-I.44C c - C-I C...34-N 04 >4 w 0 w104 -4 𔃾 1 (0O04 I E -4.4 -4,4< E-4 -4 4 EC’m ENc E -4 EN U MN m 00 .CD ’-4 CN4 = N 1I (O0004 W WW M ID~(0o WC~o .C4 .CI =(L =CC, us N...4000C4 0-44 0 0 0004 ’)n . enc (j -0 c0 0 7 3(0029 000- 00-44--C Z(co1-10- 4 0 4. 00001-< 0- 0q 0Nca co 0c 0 0m~ 00 00rc . nwu> UM )mmc 10 4 (. o r)00

Prime Contract Awards Alphabetically by Contractor, State or Country, and Place. Part 18 (University of Virginia, Carsonville, Virginia - Zymark Corporation, Hopkinton, Massachusetts), FY1991

DTIC Science & Technology

1991-01-01

C 44 ) C4 04 444)c_ _) I LC.) InflQAQ -4 < -4 -4< a 4 c - I 0)-CI I~ 000 10) 1" W .) 0 0007 10 10 LA LAY) LADO I I aH0 HO cc.4-4r 0 n r -I0 07 nc oq 0...4 (D C) -. C-4 0 IN -, r) IN N4 I3U to 04 a c( 0v o00 E co o CL0 to0 Or. Mb" be - -0) -oIn 3 1 0 3 1.W4 00 LC L.N 1C,) ENc >-0 I-N 0.0 L 6--4 L...4N E c’ m.40704mmo7 41,07 00C 0)07 -4 W07 ENC 0 If w4 6 04 66 AS0) .=07 00o momI-4-.c) 00) 4--4.-4 -40 0(D al 064 - XN0 0)1 C6 8 I CO. H:30 00 U-4

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 11 (Hilton Systems Inc -International Industries Inc)

DTIC Science & Technology

1990-01-01

A11 10 m 4(1 CI (00 10 <D 0 1(0 (4 -1 -*It j-I -ti j 1 -114 -14 1N N r > KfC i i-I - of ’D I <( m it 4 44 LAO<< U)U IL- C LAO L𔃻 ~ I- Ai>> tor)> LNMMM...4 if Z InIn In in n toIn tr onIn In Z.10- 01 o( c > ) In In n InfLn InL In I n 20 C ZIn InfIn Z In 11. if-c I (0-4 11Ir nV no U1(1() on C )() 0 I a1

Peculiarities of RFLP of highly repetitive DNA in crow genomes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chelomina, G.N.; Kryukov, A.P.; Ivanov, S.V.

1995-02-01

We present a study of the structural organization of highly repetitive DNA in genomes of hooded crow Corvus cornix L., carrion crow C. corone L., and jungle crow C. macrorhynchos Wagl. RFLP and blot-hybridization with {sup 32}P-labeled Msp I fragment from hooded crow nDNA suggest the interspecific structural conservatism of the most repetitive DNA. The family of repeats we studied had tandem organization and the same (210 bp) period of reiteration for a set of restriction enzymes. However, in parallel to the general similarity of restriction patterns, there are species-specific peculiarities. The repetitive family revealed (Alu I, BsuR I, andmore » Msp I fragments) has quantitative RFLP of nDNA and interspecific differences in the extent of the multimer {open_quotes}ladder{close_quotes} pattern of Msp I fragments. The latter is more pronounced in nDNA of carrion crow than in that of phylogenetically distant jungle crow and closely related hooded crow. This suggests a recent amplification event for highly organized homological repeats in crow genomes. 10 refs., 2 figs.« less

Prime Contract Awards Alphabetically by Contractor, By State or Country, and Place, FY 84. Part 4. (Eastern Car Construction Company - General Displays Company).

DTIC Science & Technology

1984-01-01

8217(-O0I0D 0 <C 4 4 00 0i)-0 N Z ( N- 10 00 *- ZO I o Q) <C W0Z -001 - 00 -0001- o j -ZO 0O0O- F- z0 CCi)00 4 - i co0 0: O (1) CL C00I De ) 0 I) -WL)C 0 0m 0...000 04440000 Iu.0 -, 0 0 0 DZIL DE CD LbLL Z D Z Z DI z 00 U IQC )()M-r q- Ml P, - (1 A -Nv -NvN 0.4 N. 0 0 )o C0nNO0n 00 L0 0-V o D-000-00ON -’ . 0 In...00000 00 NO ... OO 000 40 KO < DE ~ - -# 4c M Wi) wC - V0 00) 0)Ci) 0 0 ( 0N 0 )0)0I i N If N C) W _j O~D 10 0 x JN00 00 0-1 40 0 0 4- j <iWi- -O woo

Fourth standard model family neutrino at future linear colliders

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ciftci, A.K.; Ciftci, R.; Sultansoy, S.

2005-09-01

It is known that flavor democracy favors the existence of the fourth standard model (SM) family. In order to give nonzero masses for the first three-family fermions flavor democracy has to be slightly broken. A parametrization for democracy breaking, which gives the correct values for fundamental fermion masses and, at the same time, predicts quark and lepton Cabibbo-Kobayashi-Maskawa (CKM) matrices in a good agreement with the experimental data, is proposed. The pair productions of the fourth SM family Dirac ({nu}{sub 4}) and Majorana (N{sub 1}) neutrinos at future linear colliders with {radical}(s)=500 GeV, 1 TeV, and 3 TeV are considered.more » The cross section for the process e{sup +}e{sup -}{yields}{nu}{sub 4}{nu}{sub 4}(N{sub 1}N{sub 1}) and the branching ratios for possible decay modes of the both neutrinos are determined. The decays of the fourth family neutrinos into muon channels ({nu}{sub 4}(N{sub 1}){yields}{mu}{sup {+-}}W{sup {+-}}) provide cleanest signature at e{sup +}e{sup -} colliders. Meanwhile, in our parametrization this channel is dominant. W bosons produced in decays of the fourth family neutrinos will be seen in detector as either di-jets or isolated leptons. As an example, we consider the production of 200 GeV mass fourth family neutrinos at {radical}(s)=500 GeV linear colliders by taking into account di-muon plus four jet events as signatures.« less

Efficient production of acetone-butanol-ethanol (ABE) from cassava by a fermentation-pervaporation coupled process.

PubMed

Li, Jing; Chen, Xiangrong; Qi, Benkun; Luo, Jianquan; Zhang, Yuming; Su, Yi; Wan, Yinhua

2014-10-01

Production of acetone-butanol-ethanol (ABE) from cassava was investigated with a fermentation-pervaporation (PV) coupled process. ABE products were in situ removed from fermentation broth to alleviate the toxicity of solvent to the Clostridium acetobutylicum DP217. Compared to the batch fermentation without PV, glucose consumption rate and solvent productivity increased by 15% and 21%, respectively, in batch fermentation-PV coupled process, while in continuous fermentation-PV coupled process running for 304 h, the substrate consumption rate, solvent productivity and yield increased by 58%, 81% and 15%, reaching 2.02 g/Lh, 0.76 g/Lh and 0.38 g/g, respectively. Silicalite-1 filled polydimethylsiloxane (PDMS)/polyacrylonitrile (PAN) membrane modules ensured media recycle without significant fouling, steadily generating a highly concentrated ABE solution containing 201.8 g/L ABE with 122.4 g/L butanol. After phase separation, a final product containing 574.3g/L ABE with 501.1g/L butanol was obtained. Therefore, the fermentation-PV coupled process has the potential to decrease the cost in ABE production. Copyright © 2014 Elsevier Ltd. All rights reserved.

Geographic List of Prime Contract Awards. Oct 92-Sep 93. FY 93. (Amos, Kentucky-Montgomery County, Maryland). Part 6

DTIC Science & Technology

1994-03-01

r 11 c I0-eJI C1 31 00000P0) 0 (icc C) Cr) M 0 W( D(DE DW D0)o I o0)0 II.’I1)cc jinI 11 ) C\\LC\\m NA NI C111 Mr (’*4 Y MCJMMMMM (nr (YiC ) (ici MCici...0 00 0 0 III0-Ic14򒰌 OW 000 00 00 000 00 00 000> 00 0 00 11 1 l-4N II 1 N N, NN N 4 N NNN > II 10-i- 11 >- z co11111 - I\\ jINI ,-t 0 11 N N 00 Nc 4ɚ...I 0011C U.L 11 c I caoc II 00 11 E I Gao 0r, 1 -- -I .- ---- -- - - - - - - -- ----- 114- I COLD4l II 000000000000000000000000000000000000000000 00 1

Estimating USAF Aircraft Recoverable Spares Investment.

DTIC Science & Technology

1980-08-01

ITEMS Multiple Regression Equation RCCAVI - 178.44118(AC)’ 39843(AVFAC) ൰ 62 2 e 27003 (IB ) + 2.4257(1R e 1.0 9 99 (IF/A) + 1.1 8 11 (1C) + 1.100...79- I M In *~Nt M h IOOO N1 0 , C 0 0 30~ It- N t- INN0010 - t 10 N M mt00 01 0,󈧈 01c 0 0 0000’ ast-00 10%I I t~-.. ~ ISO ~ tO It- . lO tfls4 I1 MD...0K 0 4 #40 D Jr *0 2z < I 0 -I - . - - I 0 I IN , 0 H0 PA C, :,C n BCY -4 0 -a C I z nL Z4 w11 00 WI Z4 4 ) L. zWI W -98- w Iq IN N05 IsO I 5I 00 0 1

Carbonitride based phosphors and light emitting devices using the same

DOEpatents

Li, Yuanqiang; Tian, Yongchi; Romanelli, Michael Dennis

2013-08-20

Disclosed herein is a novel group of carbidonitride phosphors and light emitting devices which utilize these phosphors. In certain embodiments, the present invention is directed to a novel family of carbidonitride-based phosphors expressed as follows: Ca.sub.1-xAl.sub.x-xySi.sub.1-x+xyN.sub.2-x-xyC.sub.xy:A; (1) Ca.sub.1-x-zNa.sub.zM(III).sub.x-xy-zSi.sub.1-x+xy+zN.sub.2-x-xyC.sub.xy:- A; (2) M(II).sub.1-x-zM(I).sub.zM(III).sub.x-xy-zSi.sub.1-x+xy+zN.sub.2-x- -xyC.sub.xy:A; (3) M(II).sub.1-x-zM(I).sub.zM(III).sub.x-xy-zSi.sub.1-x+xy+zN.sub.2-x-xy-2w/- 3C.sub.xyO.sub.w-v/2H.sub.v:A; and (4) M(II).sub.1-x-zM(I).sub.zM(III).sub.x-xy-zSi.sub.1-x+xy+zN.sub.2-x-xy-2w/- 3-v/3C.sub.xyO.sub.wH.sub.v:A, (4a) wherein 0xy+z, and 0

All Prime Contract Awards by State or Country, Place, and Contractor. Part 13 (Allendale, New Jersey -Otero, New Mexico)

DTIC Science & Technology

1990-01-01

N R CA (A CAl (no L4 0 Ij)4Q # j)C U n<U U uM0 ii C-4 ɘ :: 0. H00 .- -Wt .- -()0 M L 1 L -0 nI n L 4( I M 1((0 11 44 4 44 4 44 4 4 z4 4 0) ISO ...0 > ə IMN C13 0t Z 0 044>>~ 0000c 1,41 1IM" Ŗ 1- ) I-- I-- I.- I- U4 Io 14- (I), isL)0z 00 I- ISO ION It -~W ) f z i IION N/ 0A 0 1. 2 0 on 01-- w 0...ZI o M cv ISO . CL ’) C) cn0 000 2>C) 1 0 0 -6 co C1 mI ii 2 W- 0) 0 1-4 0 0404 0 O DU)C> (c In < wi coC’ II La.) Z"I 00 I-I > w o .Joo40 C) loo oo w>0C

Stratifying empiric risk of schizophrenia among first degree relatives using multiple predictors in two independent Indian samples.

PubMed

Bhatia, Triptish; Gettig, Elizabeth A; Gottesman, Irving I; Berliner, Jonathan; Mishra, N N; Nimgaonkar, Vishwajit L; Deshpande, Smita N

2016-12-01

Schizophrenia (SZ) has an estimated heritability of 64-88%, with the higher values based on twin studies. Conventionally, family history of psychosis is the best individual-level predictor of risk, but reliable risk estimates are unavailable for Indian populations. Genetic, environmental, and epigenetic factors are equally important and should be considered when predicting risk in 'at risk' individuals. To estimate risk based on an Indian schizophrenia participant's family history combined with selected demographic factors. To incorporate variables in addition to family history, and to stratify risk, we constructed a regression equation that included demographic variables in addition to family history. The equation was tested in two independent Indian samples: (i) an initial sample of SZ participants (N=128) with one sibling or offspring; (ii) a second, independent sample consisting of multiply affected families (N=138 families, with two or more sibs/offspring affected with SZ). The overall estimated risk was 4.31±0.27 (mean±standard deviation). There were 19 (14.8%) individuals in the high risk group, 75 (58.6%) in the moderate risk and 34 (26.6%) in the above average risk (in Sample A). In the validation sample, risks were distributed as: high (45%), moderate (38%) and above average (17%). Consistent risk estimates were obtained from both samples using the regression equation. Familial risk can be combined with demographic factors to estimate risk for SZ in India. If replicated, the proposed stratification of risk may be easier and more realistic for family members. Copyright © 2016. Published by Elsevier B.V.

Equivalence Measurement Studies (Sections 1 - 4)

DTIC Science & Technology

1975-04-01

W ~ 4JJJ~4 $44 D-4C C - 4 0>N 01-a.O1- m .00 0 ca r4 ~V4) 14) 0 0 i4) 00 >... > Q)- 0 4) .ir 10 4 cc0 >%4 -,4 %4 . cI r.P 0 >t (0 4) la b 0 C)CU t4 2r...complicates some channel measurement 3-38 > 0. r~ri 04 c~0 CP co 0 Cft) 444 0 C a~ Q~ 0 0 w a. -0 40Cn I~F . " - 4, I 0 -- .2 C, W 4-J P- E -4 LA -- ý4...we readily find that ýi(t) T(F,t) y(t) +n (t) (4.15) where n(t) 77(t) ® h(t) (4.16) 4-6 4.) N. 4. ( C-7 Q) C14) La -4 4J- P4~ CNN P4 4.5 W4-4 P4 N N

Models of the Learner in Computer-Assisted Instruction

DTIC Science & Technology

1975-12-01

De ~.elopment Center San Diego, California 92152 !4" N il 0 ’U ’ UNCI.ASbp kW ILL SECURITY CLASSIVICATION OF TNO;S PAA;E 11%.. Daea t,,i...d) fREAD...and computer programaing . Advo.itional efforts are being, made to extend this approach to less formal subiect matter such as South American geography...Laubsch’s call for a time-dependent forgetting process. Despite the inclusion of a forgetting process, presentation strategies based on the family of

Childhood emotional maltreatment and mental disorders: Results from a nationally representative adult sample from the United States.

PubMed

Taillieu, Tamara L; Brownridge, Douglas A; Sareen, Jitender; Afifi, Tracie O

2016-09-01

Child maltreatment is a public health concern with well-established sequelae. However, compared to research on physical and sexual abuse, far less is known about the long-term impact of emotional maltreatment on mental health. The overall purpose of this study was to examine the association of emotional abuse, emotional neglect, and both emotional abuse and neglect with other types of child maltreatment, a family history of dysfunction, and lifetime diagnoses of several Axis I and Axis II mental disorders. Data were from the National Epidemiological Survey on Alcohol and Related Conditions collected in 2004 and 2005 (n=34,653). The most prevalent form of emotional maltreatment was emotional neglect only (6.2%), followed by emotional abuse only (4.8%), and then both emotional abuse and neglect (3.1%). All categories of emotional maltreatment were strongly related to other forms of child maltreatment (odds ratios [ORs] ranged from 2.1 to 68.0) and a history of family dysfunction (ORs ranged from 2.2 to 8.3). In models adjusting for sociodemographic characteristics, all categories of emotional maltreatment were associated with increased odds of almost every mental disorder assessed in this study (adjusted ORs ranged from 1.2 to 7.4). Many relationships remained significant independent of experiencing other forms of child maltreatment and a family history of dysfunction (adjusted ORs ranged from 1.2 to 3.0). The effects appeared to be greater for active (i.e., emotional abuse) relative to passive (i.e., emotional neglect) forms of emotional maltreatment. Childhood emotional maltreatment, particularly emotionally abusive acts, is associated with increased odds of lifetime diagnoses of several Axis I and Axis II mental disorders. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 14 (Markel Corporation-Odkro Mountain Optech Inc)

DTIC Science & Technology

1990-01-01

4-4 -- 40 -NN04OC4 Ř-f CI () I 0-4- 00 a cf-E40>-4 -4 -4 -400 D0 0a0CD0 00---4.40-0 ) so I Com ’ 11 00 0027)00 a F C 0 0 )00 0 00 CO)0)000)0a)000Y 0...to )000 COM M 00)m 0)00)0 M) 4 03 0 0I(a It 2 2222 Z 2 ZZ 2222 Z 2 2 Z 1 aLn 10 0> 0> 0 0L I jz0 rL) f W N CfI 00CC040 4 N 0-4 IIMO U) L))))C 030 M11...I-m ONO 00 00.C>< -401 - I < 4 Ill 1 1 1 1 1-ltf H4 9 .4 0 (0) (0 ("n-5 Inew .)>(i : "N . .NN .NNNNNN) ON! .mnN0"NNN 04T Com 0.-4 om ~4 U wOlN0 0 0 0

The N355K atlastin 1 mutation is associated with hereditary sensory neuropathy and pyramidal tract features.

PubMed

Leonardis, L; Auer-Grumbach, M; Papić, L; Zidar, J

2012-07-01

  Mutations in atlastin-1 (ATL-1), a gene known to cause pure, early-onset autosomal dominant hereditary spastic paraplegia SPG3A, have been recently reported to cause hereditary sensory neuropathy I (HSN I). We describe the detailed clinical and electrophysiologic findings in the first family with ulcero-mutilating sensory neuropathy carrying the c. C1065A, p.N355K mutation in ATL-1.   Detailed clinical and electrophysiologic studies were performed in affected and at-risk family members. Motor and sensory nerve conductions studies (NCS) were carried out in upper and lower limbs. ATL-1 was screened for mutations by direct sequencing.   Ten patients were found to carry the N355K mutation. With the exception of the two youngest patients, all had trophic skin changes in the feet consisting mainly of painless ulcers. Frequently, amputation of toes, feet, or even more proximal parts of the lower legs became necessary. A variable degree of increased muscle tone was observed in younger patients, whilst some older affected individuals only presented with hyperreflexia of patellar tendon reflexes. NCS revealed signs of an axonal motor and sensory neuropathies.   Our family carrying the N355K ATL1 mutation, which was initially diagnosed as HSN I, enlarges the SPG3A phenotype. We therefore suggest that patients with HSN I excluded for more common causes of HSN I, and in particular, affected individuals who exhibit additional pyramidal tract features should also be screened for mutations in ATL1. © 2012 The Author(s) European Journal of Neurology © 2012 EFNS.

Halogen Substitution Effects on N2 O Schiff Base Ligands in Unprecedented Abrupt FeII Spin Crossover Complexes.

PubMed

Phonsri, Wasinee; Macedo, David S; Vignesh, Kuduva R; Rajaraman, Gopalan; Davies, Casey G; Jameson, Guy N L; Moubaraki, Boujemaa; Ward, Jas S; Kruger, Paul E; Chastanet, Guillaume; Murray, Keith S

2017-05-23

A family of halogen-substituted Schiff base iron(II) complexes, [Fe II (qsal-X) 2 ], (qsal-X=5-X-N-(8-quinolyl)salicylaldimines)) in which X=F (1), Cl (2), Br (3) or I (4) has been investigated in detail. Compound 1 shows a temperature invariant high spin state, whereas the others all show abrupt spin transitions, at or above room temperature, namely, 295 K (X=I) up to 342 K (X=Br), these being some of the highest T 1/2 values obtained, to date, for Fe II N/O species. We have recently reported subtle symmetry breaking in [Fe II (qsal-Cl) 2 ] 2 with two spin transition steps occurring at 308 and 316 K. A photomagnetic study reveals almost full HS conversion of [Fe II (qsal-I) 2 ] 4 at low temperature (T(LIESST)=54 °K). The halogen substitution effects on the magnetic properties, as well as the crystal packing of the [Fe II (qsal-X) 2 ] compounds and theoretical calculations, are discussed in depth, giving important knowledge for the design of new spin crossover materials. In comparison to the well known iron(III) analogues, [Fe III (qsal-X) 2 ] + , the two extra π-π and P4AE interactions found in [Fe II (qsal-X) 2 ] compounds, are believed to be accountable for the spin transitions occurring at ambient temperatures. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

A System Approach to Navy Medical Education and Training. Appendix 4. Task Inventory Booklet (Form N20-Nurses).

DTIC Science & Technology

1974-08-31

AD-AG G 60 TECHN0141CS INC OAKTON VA F/G 5/9 A SYSTEM APPROACH TO NA Y M4EDICAL EDUCATION AND TRAINING. APPEN--ETC(Ul AUG 74 N00014-69-C-026...nf0 f -4 n -9 i n ISe-rial N"- 0233 _________ 5 i.1 1 NAME R y , n-M TASK ANALYSIS BACKGROUND ,NTN 6- DATA SHEET , 2S . "I S13 •6 - 1. Use No. 2 pencil...n f f t nftft nI= .4 .- i i 0193466760i01A- E Y 1 5 . ...N ! 2 9 2j 7- U u~ U U ’U -U M S D U U . W M 2 MU.U~ .t . • I I s. U, -.UM

All Prime Contract Awards by State or Country, Place, and Contractor, FY 85. Part 4 (Sandia, California - Yuba City, California).

DTIC Science & Technology

1985-01-01

4 40 v-4 N 0 -4 0 0 0 .4 coo coo N 0NNN N 0O.4 4 07 4 4 ’ ൷ 0 04 44 4 4 40-441* C4 4 .4 07-4 . 4-4 .4N 4 440 U00 0 0 0) 40) C. * IP InI w n WEQ...4 l NN N - 4C -N N -.4 N 10-4oIN N 14 (0 If ( 0 IL) IP 0 o- to) (0 (0 IO L) LI 1N .4 (0 -4 -4 -4 (0- (0 (0 -. 4 -4 4 V . (0 0l 40 CV) -It P.M 04 I -N...so 40 000Co0o0a* wo 46 4M6 0VV w* V * w 4. 600006-4 O00C,0Co0oCNCDO009-0 009 0i 009.-- 00000000009I, r- - , - 0p IP . 6j 0 04u ~ w w w w w o o m -- 0 0

Survey of United States Army Reserve (USAR) Troop Program Unit (TPU) soldiers 1989. Tabulation of Questionnaire Responses: Cross-Sectional Sample: Noncommissioned Officers (E5-E9)

DTIC Science & Technology

1989-09-30

rmJ tun )0( C0 I tow n 0 W 0 orI0~ C 0) 1! 41 4-1 0 C 0>.~ 5 114 n EL..it I~* 0o *1t0 VS I~L LC) C . L1 I 0 to -w 4. la~ L 0 c0 . ID I v- " I L-C 5. w 4...8217 II- : .. j . . . . . .I ~ L I 1 0 . 6 -I-41CIW-OW-NO C O’ 0Y O L t- 4 cc 0) 4 I1 0N6 l 0p 0 o 0 0 U ’ L I ii- L4 0~ .0N(WOWZNN 02’ 0~ ~ ZaW ~n0

The Joint US/UK 1990 Epoch world Magnetic Model

DTIC Science & Technology

1991-10-01

N cE’ "- 4 94 0 -a N fP 9u 1 I. - 4 4I opN uI uI - - - - - - -- - 9 IrI 06 ~. -A 9u. f3 0. v’ u4 -3 .0- 4 CC 00 ’C. -u -29 G- 01 W’ 10’ WCC...RE/R AR=AOR**2 C C BR=0O. BT=0O. BP=0O. BPP =O. C DO 70 N=1,MAXORD AR=AR*AOR DO 60 M=0O,N C COMPUTE UNNORMALIZED, ASSOCIATED LEGENDRE POLYNOMIALS AND...N- 1) ELSEI PP(N)=CT*PP(N I )-K(N,M)*PP(N-.2) END IF PARP=AR*PP(N) BPP = BPP +FM(M)*TEMP2*PARP ENDIF C CI 60 CONTINUE 70 CONTINUE CI C IF (ST .EQ. 0.0

EIF2AK4 Mutations in Pulmonary Capillary Hemangiomatosis

PubMed Central

Best, D. Hunter; Sumner, Kelli L.; Austin, Eric D.; Chung, Wendy K.; Brown, Lynette M.; Borczuk, Alain C.; Rosenzweig, Erika B.; Bayrak-Toydemir, Pinar; Mao, Rong; Cahill, Barbara C.; Tazelaar, Henry D.; Leslie, Kevin O.; Hemnes, Anna R.; Robbins, Ivan M.

2014-01-01

Background: Pulmonary capillary hemangiomatosis (PCH) is a rare disease of capillary proliferation of unknown cause and with a high mortality. Families with multiple affected individuals with PCH suggest a heritable cause although the genetic etiology remains unknown. Methods: We used exome sequencing to identify a candidate gene for PCH in a family with two affected brothers. We then screened 11 unrelated patients with familial (n = 1) or sporadic (n = 10) PCH for mutations. Results: Using exome sequencing, we identified compound mutations in eukaryotic translation initiation factor 2 α kinase 4 (EIF2AK4) (formerly known as GCN2) in both affected brothers. Both parents and an unaffected sister were heterozygous carriers. In addition, we identified two EIF2AK4 mutations in each of two of 10 unrelated individuals with sporadic PCH. EIF2AK4 belongs to a family of kinases that regulate angiogenesis in response to cellular stress. Conclusions: Mutations in EIF2AK4 are likely to cause autosomal-recessive PCH in familial and some nonfamilial cases. PMID:24135949

F-111D, DT and E Evaluation of Environmental Control, Airframe, Flight Control, and Secondary Power Subsystems. Appendix 2

DTIC Science & Technology

1973-12-01

la J\\ j ue J r •« t « i •••••• •••• O I Pt I A # «4 M f «I n # f^ A « | 19 «4«| # 4 K 4 N **tl 4 | «4 M ^ w...8217^•««40tV\\ lA ^n«o t𔃺«4 J ^ N- -n T» o *ma# j ra j- vO ŗ <<l ^ OfO ^ Lj ^ »/I «^ ^- O < - • • • •• • ••JJ-J-J...3 ’H i J J J -I -I • J O J\\ J- t i ^ lt) lA -*(T» »ft^lft-O^lÄO^AC» -■« Ift M «ft ♦ .fv n 3 J3 J) ^ .i> 0 J) to »O \\D iD

Novel GNE mutations in Italian families with autosomal recessive hereditary inclusion-body myopathy.

PubMed

Broccolini, Aldobrando; Ricci, Enzo; Cassandrini, Denise; Gliubizzi, Carla; Bruno, Claudio; Tonoli, Emmanuel; Silvestri, Gabriella; Pescatori, Mario; Rodolico, Carmelo; Sinicropi, Stefano; Servidei, Serenella; Zara, Federico; Minetti, Carlo; Tonali, Pietro A; Mirabella, Massimiliano

2004-06-01

The most common form of autosomal recessive (AR) hereditary inclusion-body myopathy (HIBM), originally described in Persian-Jewish families, is characterized by onset in early adult life with weakness and atrophy of distal lower limb muscles, which progress proximally and relatively spare the quadriceps. AR HIBM is associated with mutations in the UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase gene (GNE) on chromosome 9p12-13. In the present study we have identified seven novel GNE mutations in patients from five unrelated Italian families with clinical and pathologic features indicative of AR HIBM. Four were missense mutations (c.1556A>G [p.N519S], c.79C>T [p.P27S], c.1798G>A [p.A600T] and c.616G>A [p.G206S]), two consisted in a single-base deletion (c.616delG [p.G206fsX4] and c.1130delT [p.I377fsX16]) and one in an intronic single-base insertion (c.1070+2dupT). These latter findings further extend the type of GNE mutations associated with HIBM. Furthermore, in one patient we also identified the c.737G>A [p.R246Q] missense mutation that corresponds to the one previously reported in a family from the Bahamas. Interestingly, in two of our families distinct mutations affected nucleotide c.616 in exon 3 (c.616delG and c.616G>A). The possibility of specific portions of the gene being more prone to mutations remains to be elucidated. Copyright 2004 Wiley-Liss, Inc.

Report of mass communication Ceylon: October 1969-December 31, 1970.

PubMed

1971-01-01

Experience with media usage by the FPA (Family Planning Association of Ceylon between October 1969 and December 1970 is summarized. During this time, the Association purchased 100-200 column inches each of contract advertising space in 26 newspapers. The press has published 268 press release, I.P.P.F., U.N., features and international press clipping in addition to specialized medical articles on family planning methods and 8 articles by FPA office-bearers. In January 1970; the Association launched local radio's first 5-minute daily commercial in Sinhala and Tamil. The program was repeated from April to July 1970. A series of 5 slides on family planning has been shown in movie theathers and more sets are being prepared for viewing. Posters have been used on buses and are currently on display on the National Railways project. Folders, leaflect, and poster calendars have been produced and used. Family Planning stickers have put up in 700 barber saloons. The FPA had stalls in the 1970 3-day National Exhibition at Batticaloa, the 4-day U.N. Poster Exhibition at Badulla, and the 2-week Ceylon Medical College Centenary Exhibition in Colombo. The Information Unit of FPA has answered 18, 541 written inquiries. A family planning communication us regularly dispatched to members of the Cabinet, government and opposition members of parliament, senators, chairmen of local bodies, and key trade union officials.

Geographic List of Prime Contract Awards. Oct 91 - Sep 92. FY92. (Utica New York - Copan Oklahoma)

DTIC Science & Technology

1993-01-01

0 0 NISNN ISUSI0001 i 4 4 4 4 4 . is 000i z2 L 4 ZZZ2zzzzzzz 00 2 000V is -S -4 00=- 55 N4 N 4.N -4 .-4 N * LaJ 00( 11 N Z 2-6 zN ZN.. Z 4 ZN Z...qN0 is 0) .-. M0 in P- 4P 55 -44- 1-O-0( P, P- r, 11r-w-f’- * N-4 0- NO4" is q oo I-. 1-. -4 -4 4,4 14w- N -4 Go c000 N 41 I C-SO is 0 0 0 0 40...00000000000000 00 M00000000000000 M M M -4"<J05 M0- (400 55 ,ZNNZCZZCZZZZZZZZ’Z4C’JZZZZZZZZ NZZZZZZ𔃾 .1CC 01[0-TMM -Nf . 0 0-4w(to4 55 LALA L AOLOLO00

Investigation of the Effect of Low Level Maritime Haze on DMSP VHR and LF Imagery.

DTIC Science & Technology

1980-09-09

LA S LO i-4 CNJ 0) r m~X LA3 crj (N > Co -i s- - -I CN r -~ 4J. 4-4 C) 4-) >1 Cl) 0H 9 -r-( Nl NV C 0 MN (1)0 r4 s-4 L 4-)4 Uv) Cu...be approximated as : 5-12 o 0 LA r40 oD (n rn N .4 .-4 0 C14.. LA Ln LA N- 0N 0C) LA 4 . l4-) r-. LA en C4 N . 049 0 1 E-4~ . (1 0 .t 0 ’p .r LA LA LA ...w CN C1 04 .00 C4.) r -4 O N~ ’. r - CA a ’.0 LA w m~ N1 Q4-1 Ř .4.4 Q) I- Q) in - r-4 O 4 1d𔃺 -4 0 0 4J *-0 0~

Association of Urinary N-Domain Angiotensin I-Converting Enzyme with Plasma Inflammatory Markers and Endothelial Function

PubMed Central

Fernandes, Fernanda B; Plavnik, Frida L; Teixeira, Andressa MS; Christofalo, Dejaldo MJ; Ajzen, Sergio A; Higa, Elisa MS; Ronchi, Fernanda A; Sesso, Ricardo CC; Casarini, Dulce E

2008-01-01

The aim of this study was to investigate the association between urinary 90 kDa N-domain Angiotensin I-converting enzyme (ACE) form with C-reactive protein (CRP) and homocysteine plasma levels (Hcy), urinary nitric oxide (NOu), and endothelial function (EF) in normotensive subjects. Forty healthy subjects were evaluated through brachial Doppler US to test the response to reactive hyperemia and a panel of blood tests to determine CRP and Hcy levels, NOu, and urinary ACE. They were divided into groups according to the presence (ACE90+) or absence (ACE90–) of the 90 kDa ACE, the presence (FH+) or absence (FH–) of family history of hypertension, and the presence or absence of these two variables FH+/ACE90+ and FH–/ACE90–. We found an impaired endothelial dilatation in subjects who presented the 90 kDa N-domain ACE as follows: 11.4% ± 5.3% in ACE90+ compared with 17.6% ± 7.1% in ACE90– group and 12.4% ± 5.6% in FH+/ACE90+ compared with 17.7% ± 6.2% in FH–/ACE90– group, P < 0.05. Hcy and CRP levels were statistically significantly lower in FH+/ACE90+ than in FH–/ACE90– group, as follows: 10.0 ± 2.3 μM compared with 12.7 ± 1.5 μM, and 1.3 ± 1.8 mg/L compared with 3.6 ± 2.0 mg/L, respectively. A correlation between flow-mediated dilatation (FMD) and CRP, Hcy, and NOu levels was not found. Our study suggests a reduction in the basal NO production confirmed by NOu analysis in subjects with the 90 kDa N-domain ACE isoform alone or associated with a family history of hypertension. Our data suggest that the presence of the 90 kDa N-domain ACE itself may have a negative impact on flow-mediated dilatation stimulated by reactive hyperemia. PMID:18475311

H1N1: An Overview

DTIC Science & Technology

2009-08-07

Health • Prevention, Preparation and Mitigation » Seasonal Influenza » Pandemic Influenza 8/7/2009 2 Approved for Public Release, Distribution...health challenges in managing seasonal influenza and pandemics E h i ti l i di id l h lth t t i d l i th t• mp as ze some prac ca n v ua ea s ra...eg es an p ann ng a may protect employees and their families during the fall influenza season and beyond ROE: • Questions at anytime Disclaimers

Prime Contract Awards Alphabetically by Contractor, State or Country, and Place. Part 2 (American Management Systems Inc, Arlington, Virginia - Basil & Trataros JV, Loring AFB, Maine), FY1991

DTIC Science & Technology

1991-01-01

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Exact Performance of General Second-Order Processors for Gaussian Inputs

DTIC Science & Technology

1983-10-15

general than the characteristic function considered in [3, eq. 5], which itself required a very lengthy analytic treatment to get the probability...8217 1970 13=2*12 1980 I4 = N/I3 1990 FOR 15=1 TO 12 2000 I6=(:i5-l)*I4+l 2010 IF I6<=H2 THEN 2050 2020 N6 = -CCN4-I6-1 > 2030 N7 = - Ca6 -Nl-i;’ 2040...GOTO 2070 2050 N6= ca6 -i:j 2060 H7=-C(N3-I6-1) 2070 FOR 17=0 TO H-I3 STEP I 2080 18=17+15 2090 19=18+12 2100 N8 = X(I8-n-Xa9-l> 2110 N9 = Ya8-l

An Investigation of the Feasibility of Implementing Substantial Finite Element Codes on Popular Microcomputers.

DTIC Science & Technology

1982-10-01

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Fathering and the Pediatric Cancer Experience.

DTIC Science & Technology

1979-12-01

avoidance of the family as the consequence. Management of the child in the family involved in chronic illness is no easy task. A team of professionals...in fathers began with my own family and the special fatherK I had. 4t ACKNOWLEDGMENTS I wish to express my appreciation to all the following people for...friends of the Graduate Program for continued support. To my four study fathers and their families for their time, energy, and frankness. To my family for

Domestic Base Factors. Fiscal Year 1980. Volume I.

DTIC Science & Technology

1981-03-01

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Anthropometry of Women of the U.S. Army--1977. Report Number 3. Bivariate Frequency Tables

DTIC Science & Technology

1977-07-01

U4 (\\ 4. 4 (I ’ a -1 Or L - l CLJ U. L. C.)~V * . -4 W- (V (N 4 ’ ( .4~-. U., 𔃾 (- L4+ + LU. B S- AV ILBL UOYu rr~ 4.4 4~4 4~) 4- - flJ 41.4 -J 4...0 4 ^* 04L I I 4 x v0 -- 4.44- . 4- 4. . 4- 4. 4 411 I~tfl \\Jr4(A 0 N~LI S 19 Id -4 o ,4 UNN6 A NI t4 . I P.. A 4N ,j td t󈧄’- 4 (v. LA In .4 10...J %. td 0A I.- 𔃾 0 - 40 CI (TIU LA m r N?)MLA 4 0% x > co ~ r" (M -4- ) 4 (A Li * F4 ~ LA v4 𔃺 *LA %D M (%J V 4 D I.- Id . - MV -4 (Ii " CA V) X F

Health Professionals Prefer to Communicate Risk-Related Numerical Information Using "1-in-X" Ratios.

PubMed

Sirota, Miroslav; Juanchich, Marie; Petrova, Dafina; Garcia-Retamero, Rocio; Walasek, Lukasz; Bhatia, Sudeep

2018-04-01

Previous research has shown that format effects, such as the "1-in-X" effect-whereby "1-in-X" ratios lead to a higher perceived probability than "N-in-N*X" ratios-alter perceptions of medical probabilities. We do not know, however, how prevalent this effect is in practice; i.e., how often health professionals use the "1-in-X" ratio. We assembled 4 different sources of evidence, involving experimental work and corpus studies, to examine the use of "1-in-X" and other numerical formats quantifying probability. Our results revealed that the use of the "1-in-X" ratio is prevalent and that health professionals prefer this format compared with other numerical formats (i.e., the "N-in-N*X", %, and decimal formats). In Study 1, UK family physicians preferred to communicate prenatal risk using a "1-in-X" ratio (80.4%, n = 131) across different risk levels and regardless of patients' numeracy levels. In Study 2, a sample from the UK adult population ( n = 203) reported that most GPs (60.6%) preferred to use "1-in-X" ratios compared with other formats. In Study 3, "1-in-X" ratios were the most commonly used format in a set of randomly sampled drug leaflets describing the risk of side effects (100%, n = 94). In Study 4, the "1-in-X" format was the most commonly used numerical expression of medical probabilities or frequencies on the UK's NHS website (45.7%, n = 2,469 sentences). The prevalent use of "1-in-X" ratios magnifies the chances of increased subjective probability. Further research should establish clinical significance of the "1-in-X" effect.

Does aging make employees more resilient to job stress? Age as a moderator in the job stressor-well-being relationship in three Finnish occupational samples.

PubMed

Mauno, Saija; Ruokolainen, Mervi; Kinnunen, Ulla

2013-01-01

This study examined whether an employee's age moderates the relationships between job stressors (i.e. job insecurity, workload, work-family conflict) and self-rated well-being (i.e. work-family enrichment, life satisfaction, job satisfaction, vigor at work). Analysis of covariance and moderated hierarchical regression analysis were used to examine the cross-sectional Finnish data collected among service sector employees (N = 1037), nurses (N = 1719), and academic employees (N = 945). In a situation of high job insecurity, the younger nurses reported higher work-family enrichment, job satisfaction, and vigor compared to their older colleagues. A similar result was also found among the service sector workers in relation to vigor at work. Thus, young age buffered against negative outcomes related to job insecurity. Moreover, older age buffered against the negative effect of high workload on job satisfaction among the service sector and against high work-family conflict on life satisfaction among the academic employees. More attention should be paid to the ability of younger employees to manage problems related to work-family imbalance and high workload, and to older employees' ability to cope with job insecurity. The findings of this study recommend different stress management interventions for older and younger employees.

Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Resource Applications In - Seton Hall University). Part 16

DTIC Science & Technology

1994-03-01

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Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Bt North America Inc. - Classified Location Domestic)

DTIC Science & Technology

1994-03-01

V4,(41, Or,.in cri nN c >1r- 0 10 f tao oinon0 40 M-4 -4 td n -w toce, of IC 𔃺 0 ca I1-&n UO0 - qtY(DC -04N I- . 30 C S-i Ur’L) . L-M4 U -4~ C...d 0o II Nca( 0 CI400W000 CD 10) Ny It 4. ev MNN.P.P rn If CIL I co00t I’l -4 co0 00000 -00 0 00C) 0 CV 4.4 Me V DCo tD H11 10 004D11 Nm Oin 000000...CO -4 0 11 -2c z .- Z 11 1 CO 0 fm 11 C z 2c z ed C z zx If I ca a 00 11 1- ed tv (d I td III 11 1 00000 11 00-t .- !`ý- W M It r- Ln Ln 0 tma N -4 -4

All Prime Contract Awards by State or Country, Place, and Contractor. Part 15 (Amity N. Dakota-Tulsa Oklahoma)

DTIC Science & Technology

1990-01-01

m2 .m2 =~Z ZZ222* .=222* .=2222 moo 400 10 0 0- 0 0 00 0 0 OHp so 0I0moo 1.- r- .1 D 0> 00󈧬.1-N c>0In 0)(000-4-4 41) I 1 400 Y ’ 0 m’ -4 N-T 4101...0 00-4a4-4.-4-0 N 14 I 00 0) 0) 0) 0)0) 0)00) 0) MEM N1 C4 0) II 0) -4r- In r 00) Nl 0 In n Njo oo in -4 r-t-N a -4 o II I M) It -4MCMn"CNNN NOj 0 U00

Associations between Relational Pronoun Usage and the Quality of Early Family Interactions.

PubMed

Galdiolo, Sarah; Roskam, Isabelle; Verhofstadt, Lesley L; De Mol, Jan; Dewinne, Laura; Vandaudenard, Sylvain

2016-01-01

Our study examined the relationships of relational pronouns used in parental conversation to the quality of early family interactions, as indexed by Family Alliance (FA). We hypothesized that more positive family interactions were associated with the use of more we-pronouns (e.g., we, us, our; we-ness ) and fewer I- and you-pronouns (e.g., I, me, you, your; separateness ) by both mothers and fathers. Our statistical model using a multilevel modeling framework and two levels of analysis (i.e., a couple level and an individual level) was tested on 47 non-referred families ( n = 31 primiparous families; child's age, M = 15.75 months, SD = 2.73) with we-ness and separateness as outcomes and FA functions as between-dyads variables. Analyses revealed that we-ness within the parental couple was only positively associated with family affect sharing while separateness was negatively associated with different FA functions (e.g., communication mistakes). Our main finding suggested that the kinds of personal pronouns used by parental couples when discussing children's education would be associated to the emotional quality of the family interactions.

Associations between Relational Pronoun Usage and the Quality of Early Family Interactions

PubMed Central

Galdiolo, Sarah; Roskam, Isabelle; Verhofstadt, Lesley L.; De Mol, Jan; Dewinne, Laura; Vandaudenard, Sylvain

2016-01-01

Our study examined the relationships of relational pronouns used in parental conversation to the quality of early family interactions, as indexed by Family Alliance (FA). We hypothesized that more positive family interactions were associated with the use of more we-pronouns (e.g., we, us, our; we-ness) and fewer I- and you-pronouns (e.g., I, me, you, your; separateness) by both mothers and fathers. Our statistical model using a multilevel modeling framework and two levels of analysis (i.e., a couple level and an individual level) was tested on 47 non-referred families (n = 31 primiparous families; child’s age, M = 15.75 months, SD = 2.73) with we-ness and separateness as outcomes and FA functions as between-dyads variables. Analyses revealed that we-ness within the parental couple was only positively associated with family affect sharing while separateness was negatively associated with different FA functions (e.g., communication mistakes). Our main finding suggested that the kinds of personal pronouns used by parental couples when discussing children’s education would be associated to the emotional quality of the family interactions. PMID:27847495

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 4. (Campbell and Parts Engineers-Comstron Corporation)

DTIC Science & Technology

1989-01-01

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Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1987. Part 19. United Ameritec Corporation-Waste Management, Incorporated.

DTIC Science & Technology

1987-01-01

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Molecular Surface Electrostatic Potentials in the Analysis of Non- Hydrogen-Bonding Noncovalent Interactions

DTIC Science & Technology

1993-12-27

the parent compound of a large family of derivatives, most of which do not cocrystallize with guest molecules (Etter, et al., 1990). Even when put into...shown below (9) instead of forming cocrystals (e.g. 10). 0/ 0 2N NO2 11 0 "N’"N NH I I’~ H H / HH S II 9 10 We have proposed that the tendency for 8 to

Outpatient Nonavailability Statement Procedures, Health Services Command Catchment Areas, Second Quarter FY 1993 with Comparisons to First Quarter FY 1993

DTIC Science & Technology

1993-04-16

9n W! 0. - 1ý z1 - 9w -u : C9 L& x u 0,0 m L3* omp m rayo co 00 0 r4U iao a, - -C9~ m iz .J J ,4cfC4z Ge .4 th in Nn ini~ N 0 . - 0M 4Im o-1~ 4a4 a...n o . 3:W N `0It C 0.O In ?K. 0 )10 S C j0 .0 > .0N ~ O -r . -~r- 0 I0-i cc0 CL.Q 0 ~ N’- t X . 0. 0.0 kn .t.O 0 N- ýA 0. O L.MwNc 0 ’ C. C’ . c, ’r...0C. 0> In .- -fn 0 00. 0. -) 0 O 0 I- nI 1 l L I.-~~ ~ Nui -j V). Un 4A𔄀 f m n U =0 -K 0 4 A.f u x ý U) 00 i n f- ’ , ý O ac -00 L) b- -C u) ý .- 𔃻

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 2 (Allied Supply Co Inc-Ashley Machine & Tool Co)

DTIC Science & Technology

1990-01-01

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Official Guard and Reserve Manpower Strengths and Statistics, FY 1987.

DTIC Science & Technology

1987-06-01

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Microfilm and Computer Full Text of Archival Documents

DTIC Science & Technology

1988-10-13

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Terminal Area Forecasts, FY 1993-2005

DTIC Science & Technology

1993-07-01

0 td U) ~ 4-) 4.J.4 0 J~ :s 0- -"C4 4o U ).4CO ) 0 u *Wý44 o 41C kdQ(n v 00 UrC~ 4) -4 0 M 0~ 4j > (D M kca 41 Ř b bO CA -A~ ..O 0 .0 Cd~ bl ~ - k...o tD ~ Hr- Nr,- `4v oH f n% oM 0( ON %D ~H w H LnODH (1 O O D DO ODG OD 00 OhOh(T ma % m %0 HC4.Ch h %Ch( i % )d% HN 4J H 1-0 %D- O M (NWN DU VO D...I ~ J)I C1 F "H OD ,- V 1 D ( -r r -4 Ch’. ON 00 -4 c,4 mu) n( (n A;1 m tD b r-4 rJ’q~~ I Nr-W L o 0 ( O HM N~ - I- IV N- M M O ’ rI % NN . OD U NCh0

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 5 (CSR INC-Colson Business Systems Inc)

DTIC Science & Technology

1990-01-01

000 00 4U I CON U4 a’ 2 3- ’- 001-- I M3 ON U4 4C 2 w w 002 CDZ Co QOUGI N U~s I 1- 1 * 0 0 2 0 000 00 < U 0 I ON U 00 2 I ZNS 0N0!0v)1.- 00000-1 Col...W of M- If’ H c -40oo04 0 0. -40 0C0 040 I Io 00 II M000M. 00 M000. 000 004M 0) 00- 000 L) IO coM 1 00 0044 f-4 in a*0) -4 0r14 - -G o I cON I l 0 0...Moo O I N ca fl00 0000 -. 0 0 0) 0U 00 0 0C) M Mj a l 4I0I ON I4 Wr 01-li N 0C-.J i -Nm-W)- r SIt2 I CON I ClI 4 0 M- I.0 1-1 1N O 01 41 39 1 IO ON

Silver(I) complexes with DNA and RNA studied by Fourier transform infrared spectroscopy and capillary electrophoresis.

PubMed Central

Arakawa, H; Neault, J F; Tajmir-Riahi, H A

2001-01-01

Ag(I) is a strong nucleic acids binder and forms several complexes with DNA such as types I, II, and III. However, the details of the binding mode of silver(I) in the Ag-polynucleotides remains unknown. Therefore, it was of interest to examine the binding of Ag(I) with calf-thymus DNA and bakers yeast RNA in aqueous solutions at pH 7.1-6.6 with constant concentration of DNA or RNA and various concentrations of Ag(I). Fourier transform infrared spectroscopy and capillary electrophoresis were used to analyze the Ag(I) binding mode, the binding constant, and the polynucleotides' structural changes in the Ag-DNA and Ag-RNA complexes. The spectroscopic results showed that in the type I complex formed with DNA, Ag(I) binds to guanine N7 at low cation concentration (r = 1/80) and adenine N7 site at higher concentrations (r = 1/20 to 1/10), but not to the backbone phosphate group. At r = 1/2, type II complexes formed with DNA in which Ag(I) binds to the G-C and A-T base pairs. On the other hand, Ag(I) binds to the guanine N7 atom but not to the adenine and the backbone phosphate group in the Ag-RNA complexes. Although a minor alteration of the sugar-phosphate geometry was observed, DNA remained in the B-family structure, whereas RNA retained its A conformation. Scatchard analysis following capillary electrophoresis showed two binding sites for the Ag-DNA complexes with K(1) = 8.3 x 10(4) M(-1) for the guanine and K(2) = 1.5 x 10(4) M(-1) for the adenine bases. On the other hand, Ag-RNA adducts showed one binding site with K = 1.5 x 10(5) M(-1) for the guanine bases. PMID:11509371

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clouston, Laura J.; Bernales, Varinia; Carlson, Rebecca K.

Expanding a family of cobalt bimetallic complexes, we report the synthesis of the Ti(III) metalloligand, Ti[N(o-(NCH2P(iPr)2)C6H4)3] (abbreviated as TiL), and three heterobimetallics that pair cobalt with an early transition metal ion: CoTiL (1), K(crypt-222)[(N2)CoVL] (2), and K(crypt-222)[(N2)CoCrL] (3). The latter two complexes, along with previously reported K(crypt-222)[(N2)CoAlL] and K(crypt-222)[(N2)Co2L], constitute an isostructural series of cobalt bimetallics that bind dinitrogen in an end-on fashion, i.e. [(N2)CoML]-. The characterization of 1–3 includes cyclic voltammetry, X-ray crystallography, and infrared spectroscopy. The [CoTiL]0/– reduction potential is extremely negative at -3.20 V versus Fc+/Fc. In the CoML series where M is a transition metal, themore » reduction potentials shift anodically as M is varied across the first-row period. Among the [(N2)CoML]- compounds, the dinitrogen ligand is weakly activated, as evidenced by N–N bond lengths between 1.110(8) and 1.135(4) Å and by N–N stretching frequencies between 1971 and 1995 cm–1. Though changes in νN2 are subtle, the extent of N2 activation decreases across the first-row period. A correlation is found between the [CoML]0/– reduction potentials and N2 activation, where the more cathodic potentials correspond to lower N–N frequencies. Theoretical calculations of the [(N2)CoML]- complexes reveal important variations in the electronic structure and Co–M interactions, which depend on the exact nature of the supporting metal ion, M.« less

Youth Attitude Tracking Study II Wave 16 -- Fall 1985. Supplementary Tabulations,

DTIC Science & Technology

1986-02-01

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Association of polymorphic variants of PTPN22, TNF and VDR genes in children with lupus nephritis: A study in Colombian family triads.

PubMed

Garavito, Gloria; Egea, Eduardo; Fang, Luis; Malagón, Clara; Olmos, Carlos; González, Luz; Guarnizo, Pilar; Aroca, Gustavo; López, Guillermo; Iglesias, Antonio

2017-06-01

Systemic lupus erythematosus is an autoimmune disease in which the severity varies according to race, sex and age of onset. This variation is also observed in the genetic markers associated with the disease, including PTPN22, VDR and TNF genes. The genetic stratification in different populations worldwide can influence the variability. To analyze the heritability of PTPN22, VDR and TNF genetic variants and their association with pediatric lupus nephritis in Colombian families. We conducted a family-based study including 46 triads (case, father and mother). The variants rs2476601 of PTPN22; rs361525 and rs1800629 of TNF, and TaqI [rs731236], ApaI [rs7975232], BsmI [rs1544410] and FokI [rs2228570] of VDR were genotyped by qPCR. The effects of overtransmission of the risk allele from parents to children and linkage disequilibrium at the VDR and TNF loci were estimated. We found that allele A of rs2476601 in PTPN22 was distributed among 8.69 % (n=16) of the parents and 19.5 % (n=18) of the cases; this allele was overtransmitted from parents to children 17 times more often than the G allele (p=0.028). TNF and VDR polymorphisms did not exhibit transmission disequilibrium. VDR TaqI, ApaI and BsmI variants exhibited linkage disequilibrium. These findings showed an association between the PTPN22 rs2476601 polymorphism and pediatric lupus nephritis due to its overtransmission in the group of families studied.

Summary of Meteorological Observations, Surface (SMOS) for Moffett Field, California

DTIC Science & Technology

1988-12-01

ini#Awintinwi *i in . o * a,* %a.P..t-a a. a ko Lr.po WWo A i P P. P. 0 P. ea a a 00000Ř cibli .0 411,"a’m Al’n ~ s-a "Is inas a I 01 .4 414 .. 0 10 1... Chit S * * * * *ell* * s-IN i 9- 140 900090T.4.4 % 9 o94 em " 014lmew n in I" .j 0 04 a4 & - o1$0.0.0 .4N9 9 0001 b. ho 1 O0 S9.SS* n*0 of a - w - U...0 9 - z’n 0--IZ 4 00* hi N Chit ~~ W a a d * z ft ’I. ’r0 I 9 w 0 -o I D X M 61 41.I&I - 31 I NA ZOO CaW .-9 C3Ng0 Q .) Q 0 Q U00O c C "LJ **** .*.. C3

Developing and Pilot Testing the Readiness and Motivation Interview for Families in Pediatric Weight Management.

PubMed

Geller, Josie; Avis, Jillian; Srikameswaran, Suja; Zelichowska, Joanna; Dartnell, Katie; Scheuerman, Bailey; Perez, Arnaldo; Rasquinha, Allison; Brown, Krista E; Chanoine, Jean-Pierre; Ball, Geoff

2015-12-01

Clinical acumen is often used to assess families' motivation prior to initiating pediatric obesity management due to a lack of available tools. The purpose of this pilot study was to (i) develop and (ii) pilot test the "Readiness and Motivation Interview for Families" (RMI-Family) in pediatric weight management. We conducted 5 focus groups with parents (n = 15), youth with obesity (n = 11), and health care providers (n = 8) to explore perceptions of barriers to making healthy behaviour changes, which led to the creation of the RMI-Family as a semi-structured interview. Five domains (treat foods, overeating, emotional eating, total physical activity, and screen time) emerged from the focus groups to inform the development of the RMI-Family, which was then pilot tested with a sample of youth with obesity and their parents (n = 11 dyads). Interviewers administered the RMI-Family to youth (age 12.8 ± 1.7 years; body mass index [BMI] z-score: 2.71 ± 0.43) and parents (age 47.1 ± 3.7 years; BMI: 33.5 ± 10.1 kg/m(2)). The RMI-Family was feasible to administer, easily understood by families, and may be a useful tool for assessing families' motivation. Research is underway to determine the psychometric properties and utility of the RMI-Family in predicting clinical outcomes in pediatric weight management.

One Interesting Family of Diophantine Triplets

ERIC Educational Resources Information Center

Deshpande, M. N.

2002-01-01

In this note properties of two sequences generated by the recurrence relation G[subscript n] +2 = 4 G[subscript n] +1 - G[subscript n], are studied. It is shown that one of the sequences leads to a family of diophantine triplets. Some interesting properties of these sequences are also established.

Bond strengths of toluenes, anilines, and phenols: to hammett or not.

PubMed

Pratt, Derek A; DiLabio, Gino A; Mulder, Peter; Ingold, K U

2004-05-01

The Hammett equation correlates the effects of Y on many different chemical properties of YC(6)H(4)ZX families of compounds. One of the most surprising is that the Z-X bond dissociation enthalpy (BDE), a homolytic property, can be correlated for some 4-YC(6)H(4)ZX families with electrophilic substituent constants, sigma(p)(+)(Y), which were largely derived from the rates of the heterolytic S(N)1 solvolyses of para-substituted cumyl chlorides. Although there is no Hammett correlation of the C-X BDEs in 4-YC(6)H(4)CH(2)X (X = H, halide, OPh) families, there are good correlations of N-X BDEs with sigma(p)(+)(Y) in 4-YC(6)H(4)NHX (X = H, CH(3), OH, F) and excellent correlations of O-X BDEs with sigma(p)(+)(Y) in 4-YC(6)H(4)OX (X = H, CH(3), CH(2)Ph) families. The reasons for this varied behavior are discussed.

Prime Contract Awards Alphabetically by Contractor, State or Country, and Place. Part 1 (102 Construction Inc, Oklahoma City, Oklahoma - American Management Systems Inc, Linthicum, Maryland), FY1991

DTIC Science & Technology

1991-01-01

20 z 00 0 0 0 U 0 Q 0 ge N iI co cm 0 I.- 1.- 00)o 0 -4 " I.- " .- Z. -4 P.- ZV F- CC a 2 $ toN U1 no 0j C o4 cI 0 F6 - C - P.- 0) 540 C) "o0 6-U M...0 40 0 0 C4 0. 0 0 0 -0 400 0 U I 4N0a a .0. Nl -.4-. .1 .4 -4-I -4 W4 -6 0.4-4 Ř U 0490 0. .OW co co) 4c Lo cco c) co) toA inL0) ACCA C I -N4C a4... f6 ION *600 0 co 0 C.) 00 - o - 46 IOMN a- x-2 Za a N o 0 -C-0 0- 1-- W41 30 10 64V 8- 4 0 0- 41 41) 0 0 0 1NIO Wr1- z 2 I- 10 20 I. 0 1- ION1 NO 4

Prime Contract Awards of $100,000 or More by Federal Supply Classification or Service Category and Purchasing Office, FY 88. Part 5. (S215-Z299).

DTIC Science & Technology

1988-01-01

4 N 00 ( AccA % 0 4 00.-.0-..4 V 41 0 -C 0 00 ~I-" . 0( rU 4c 04 w Of0"al-t c - 9-0 0 -C I.-n 0.O .- O (𔃻 30- ----- -------- - 00 N4-4 0 -4 Nj~cU -Io...top- Q -0~ f3 -I 00O.~,3loG00 (n.j -4N4N.4 w-.00 .44. ..- ’J - 0 Wa W .zO . 0S 3-4 40 :I-N so 00 0’ 0 004 PIC 4vollam " 40mnC0(’- mnvmGOmfl0Q0 -4 .1

Cyclotron production of I-123: An evaluation of the nuclear reactions which produce this isotope

NASA Technical Reports Server (NTRS)

Sodd, V. J.; Scholz, K. L.; Blue, J. W.; Wellamn, H. N.

1970-01-01

The reactions studied which produce I-123 directly were Sb-121(He-4,2n) I-123, Sb-121(He-3,n) I-123, Te-122(d,n) I-123, Te-122(He-4,p2n) I-123, Te-122(He-3,pn) I-123, and Te-123(He-3,p2n) I-123. Reactions which produce I-123 indirectly through the positron decay of 2.1-hour Xe-123 were Te-122(He-4,3n) Xe-123, Te-122(He-3,2n) Xe-123 and Te-123(He-3,3n) Xe-123. Use of the gas flow I-123 cyclotron target assembly is recommended for the production of I-123 with radiochemical purity greater than 99.995%.

M-X Environmental Technical Report. Socioeconomic Impact Estimates for Texas ROI Counties. Detailed Tables.

DTIC Science & Technology

1980-12-22

C LC0 a F L(i :> I c,. r- DC -0. _j- F 0> FL F . >m xz_ v Fj j . Z Z’- >0 D 14 4 iCC Li CO 04F _j- 4 .C(nm bC 4. u o 0j l 0 <--- m xcw -n Z 0 .j F -j... lC0 0 - (- rd WIj -I IOO 0- D 0 Id0 In miL r0 m Ii Qi W. Q N _j n z w < I S-i < N Iu m I I N jw > -N Ni Ih Ij j> L n -j> E r I ’ -I aIi ’ It 0 I ) x

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 88. Part 4. (Burnside-Ott Avi. Training Ctr.-Colcom, Inc.)

DTIC Science & Technology

1988-01-01

AD-.A207 773 D DCMNAI 773I Form Approved DOCUMENTATION PAG . OMB No. 0704-0188 la . REPORT SECURITY CLASSIFICATION lb. RESIH CTIVE MARKINGS T1TneI1...CK00 dx co00 ~00 ~0w 06300-4 Iwo 6Ŕ L-4-0 W-4 W001 La IO000 W,4 wo woo WNCI wo WO00-4 I -JO -JO _300 -1.JW -.1N -acOO -a00 -JO _aOO -JO -J.O WO.J 3 0...30 300 I 3= I LA . I.. 0 1300 300I ( IlL. :40" IN (D 000 (0 -IN t-N PN00 NW) V Ch(0 N N0 WN NN- n 44൰cN N.o 0 0) WNal anW m&o W*00W 0)0 40 Nat 0)(to c

A Latent Profile Analysis of Latino Parenting: The Infusion of Cultural Values on Family Conflict.

PubMed

Ayón, Cecilia; Williams, Lela Rankin; Marsiglia, Flavio F; Ayers, Stephanie; Kiehne, Elizabeth

The purpose of the present study was to (a) examine how acculturation and social support inform Latinos' parenting behaviors, controlling for gender and education; (b) describe parenting styles among Latino immigrants while accounting for cultural elements; and (c) test how these parenting styles are associated with family conflict. A 3 step latent profile analysis with the sample ( N = 489) revealed best fit with a 4 profile model ( n = 410) of parenting: family parenting ( n = 268, 65%), child-centered parenting ( n = 68, 17%), moderate parenting ( n = 60, 15%), and disciplinarian parenting ( n = 14, 3%). Parents' gender, acculturation, and social support significantly predicted profile membership. Disciplinarian and moderate parenting were associated with more family conflict. Recommendations include integrating culturally based parenting practices as a critical element to family interventions to minimize conflict and promote positive youth development.

Installation Restoration Program (Sites 1, 2, 3, 4, 5, 8, 13). Phase 4. Remedial Action Plan and Conceptual Documents, Edwards AFB, California

DTIC Science & Technology

1984-11-01

R &D investigations. 1.3 PHASE IV SITE DESCRIPTIONS I Three primary sites are included in this Phase IV...34C z I L . ...- I I E I I i -\\ = _ _ _ . .. .....,. . .. .. I x FIGURE 1.7 a qq"-.. .. .. .. .. .. "- _ r JI I g I I1 ,n I , I I I " I - I Br-.,,-%~l...0 0 4J 4) 44 4) V ) -H 0 4 6: 144 d 0 4 14 404)-4 -4 4 .4 N ) 4 0 4) 𔃾 4 40 4) 4) 0.0

Catapulting Shifts in Images, Understandings, and Actions for Family Members through Research-Based Drama

ERIC Educational Resources Information Center

Dupuis, Sherry L.; Gillies, Jennifer; Mitchell, Gail J.; Jonas-Simpson, Christine; Whyte, Colleen; Carson, Jennifer

2011-01-01

This article examined how images, understandings, and actions change for family members of persons with dementia after the introduction of a research-based drama called I'm Still Here. Guided by interpretivist phenomenology, a set of seven pre- and post-performance focus groups were conducted with family members (n = 48) in four cities. Findings…

Family structure and risk behaviors: the role of the family meal in assessing likelihood of adolescent risk behaviors

PubMed Central

Goldfarb, Samantha; Tarver, Will L; Sen, Bisakha

2014-01-01

Background Previous literature has asserted that family meals are a key protective factor for certain adolescent risk behaviors. It is suggested that the frequency of eating with the family is associated with better psychological well-being and a lower risk of substance use and delinquency. However, it is unclear whether there is evidence of causal links between family meals and adolescent health-risk behaviors. Purpose The purpose of this article is to review the empirical literature on family meals and adolescent health behaviors and outcomes in the US. Data sources A search was conducted in four academic databases: Social Sciences Full Text, Sociological Abstracts, PsycINFO®, and PubMed/MEDLINE. Study selection We included studies that quantitatively estimated the relationship between family meals and health-risk behaviors. Data extraction Data were extracted on study sample, study design, family meal measurement, outcomes, empirical methods, findings, and major issues. Data synthesis Fourteen studies met the inclusion criteria for the review that measured the relationship between frequent family meals and various risk-behavior outcomes. The outcomes considered by most studies were alcohol use (n=10), tobacco use (n=9), and marijuana use (n=6). Other outcomes included sexual activity (n=2); depression, suicidal ideation, and suicide attempts (n=4); violence and delinquency (n=4); school-related issues (n=2); and well-being (n=5). The associations between family meals and the outcomes of interest were most likely to be statistically significant in unadjusted models or models controlling for basic family characteristics. Associations were less likely to be statistically significant when other measures of family connectedness were included. Relatively few analyses used sophisticated empirical techniques available to control for confounders in secondary data. Conclusion More research is required to establish whether or not the relationship between family dinners and risky adolescent behaviors is an artifact of underlying confounders. We recommend that researchers make more frequent use of sophisticated methods to reduce the problem of confounders in secondary data, and that the scope of adolescent problem behaviors also be further widened. PMID:24627645

Official Guard and Reserve Manpower Strengths and Statistics: Fiscal Year 1988 Summary

DTIC Science & Technology

1988-09-01

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Prime Contract Awards over $25,000 by State, City, and Contractor. Fiscal Year 1993 (Oct-Sep). (Alachua, Florida-Wreniham, Mass.). Part 2

DTIC Science & Technology

1994-03-01

m W m = w m W < w CI OWL W=>a W Z W C~ :- au-Cc!. 4J -J-- f u m - o uwaU U CL I a 4<c c0Z O O -- W W o = = w w U W W W O C 4w zaw a U UJ Wj x l- W c...w ca Z CL 4 40) w% OO) L LL100M ZO)! % w4~ ~~~~ 0100 u :x I.-N -i I 0 4c OU N NC4cn4 )C 41a 0 CA w4 I- N< .4 ON =~~ N Ni ɘ" Ul tUn .4 "=-- N.-i N 0...8217 ca (in u m 0C c j V u I-IAU~no ý X~< "I-x 4a o0 - A 00 *’-> ao mýO 000 u DC .4" L)LIL 9 -4 0> 0-.-z t.- zaW WO U--aý U UO WL OL a4(D WýXaý anýO m tx

Revised Uniform Summary of Surface Weather Observations for Vandenberg AFB, California, MSC 723930. Parts A-F

DTIC Science & Technology

1985-05-01

4 sq Al U-X z a’ M 4n al Ni Z u 0I a, -z Con % ui1 ~o* uU cc< 0u :’_ - x LZ Wa IL aw 44 _ X1 9 .j u " ift 13 4 W WIL Of 110’~ aR e Mi Ui 6 U2, D 0 4 u...ginA r ln In n n 4 .0 at ~ N t . I- -iN 0000v 0 v0 0 A0.. 00vN4 - V 0M iNinMfN N. M a 0 P. P. 0000 00000 Samoa 000memo40 gMO P: 1. 0 m9,a a .1 z *J Z...u oa . ow i ob to- fa U F a 0 a 4 0 0 00 Co Eq Eq 0 W vw Moo f - 0 *a 1040 - d - oo - -w_--_ _ 4Fe A AV 42~ PRO i it a 1 -- ’We-- _ - - - te 03 0 0

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 85. Part 19 (Star & Stripes - Tokimori Kensetsu Co Ltd).

DTIC Science & Technology

1985-01-01

GROUP SU-TOU Accession~ F’r I$ A-.TPAC" (Continue on reverse if necessary and identify by block number) DT10 TAg F U11, A n.. el ,r I-; r i...moi-z o~- w o 0 I" 1P. o zm <wxcz xu 0 -WŔIQ~l-o&~w oC0M I- 6m < w :D < Z" V) U 4 I.-lz. ’-4 1-" EL 0 0 3-1-U-04-4 0.0-" 0 00001 00o ~ oWW4xw-w"’’- 0...4-1 COD100.-4’)S 166 V_1C’St.f l.P CS (0 cmS V) el IRS 00000000000000 tA W-"NSI IS 4 c (4800-40 a N N N N N CN CN Nm Nm N4 CNI N NNINNN * 0 0 5

Effects of P/Ni ratio and Ni content on performance of γ-Al2O3-supported nickel phosphides for deoxygenation of methyl laurate to hydrocarbons

NASA Astrophysics Data System (ADS)

Zhang, Zhena; Tang, Mingxiao; Chen, Jixiang

2016-01-01

γ-Al2O3-supported nickel phosphides (mNi-Pn) were prepared by the TPR method and tested for the deoxygenation of methyl laurate to hydrocarbons. The effects of the P/Ni ratio (n = 1.0-2.5) and Ni content (m = 5-15 wt.%) in the precursors on their structure and performance were investigated. Ni/γ-Al2O3 was also studied for comparison. It was found that the formation of AlPO4 in the precursor inhibited the reduction of phosphate and so the formation of nickel phosphides. With increasing the P/Ni ratio and Ni content, the Ni, Ni3P, Ni12P5 and Ni2P phases orderly formed, accompanying with the increases of their particle size and the amount of weak acid sites (mainly due to P-OH group), while the CO uptake and the amount of medium strong acid sites (mainly related to Ni sites) reached maximum on 10%Ni-P1.5. In the deoxygenation reaction, compared with Ni/γ-Al2O3, the mNi-Pn catalysts showed much lower activities for decarbonylation, Csbnd C hydrogenolysis and methanation due to the ligand and ensemble effects of P. The conversion and the selectivity to n-C11 and n-C12 hydrocarbons achieved maximum on 10%Ni-P 2.0 for the 10%Ni-Pn catalysts and on 8%Ni-P2.0 for the mNi-P2.0 catalysts, while the turnover frequency (TOF) of methyl laurate mainly increased with the P/Ni ratio and Ni content. We propose that TOF was influenced by the nickel phosphide phases, the catalyst acidity and the particle size as well as the synergetic effect between the Ni site and acid site. Again, the hydrodeoxygenation pathway of methyl laurate was promoted with increasing P/Ni ratio and Ni content, ascribed to the phase change in the order of Ni, Ni3P, Ni12P5 and Ni2P in the prepared catalysts.

Dollar Summary of Federal Supply Classification and Service Category by Company. Part 9 (6150-7030)

DTIC Science & Technology

1990-01-01

0If 0 0 I in0 .c a i L w I. w 0 L " IZ IK 1- - 4c 8 - 2w w w 0 c I 4 I V0z z z cc zz 0 0 1 -- I I 8- C- 9- C32m I I 1 0 2 (00 acCa IO I W z 0 hi hi w...4 O go w1. 0 a4 C 0~. 0 0 WE IAJ 0 - 60 a La a im L . C 0 # a 4 a 0 f6 I . *o a W 0P -N V- 04m N .4 C- qr .4 -4 4 qv v (IP 4 N- 94 S .4 . 0I 0. -;i

A Fixed Point Theorem in Weak Topology for Successively Recurrent System of Set-Valued Mapping Equations and Its Applications

NASA Astrophysics Data System (ADS)

Horiuchi, Kazuo

Let us introduce n (≥ 2) mappings fi(i = 1, …, n ≡ 0) defined on reflexive real Banach spaces Xi-1 and let fi : Xi-1 → Yi be completely continuous on bounded convex closed subsets X_{i-1}^{(0)} \\\\subset X_{i-1}. Moreover, let us introduce n set-valued mappings F_i : X_{i-1} \\\\times Y_i \\\\to {\\\\cal F}_c(X_i) (the family of all non-empty compact subsets of Xi), (i=1, …, n ≡ 0). Here, we have a fixed point theorem in weak topology on the successively recurrent system of set-valued mapping equations: xi ∈ Fi(xi-1, fi(xi-1)), (i=1, …, n ≡ 0). This theorem can be applied immediately to analysis of the availability of system of circular networks of channels undergone by uncertain fluctuations and to evaluation of the tolerability of behaviors of those systems.

The Analysis of Social Insurance Benefits Provided for the Indonesian Military Personnel.

DTIC Science & Technology

1984-06-01

PROVIDED FOR THE IIDONESIA TI ’ "MITRV PFRF(CM’’ VEL LLa by Edy ’loeuroho 2Tune 1’lo 4 Thesis Advisor: Shu Liao A omroved ’or ivublic rloase, distribution...8217 :’ 0O 0 N 001~10 ia me o’r-4 aCQ - r . >4 4 r’ aden Co~ ’. n (D Z? 0~ =r en N --I a 4 P4 aI Ie 0 1 I I 10 0 0100 0 0 0 0 04 4 lI I I h E- 4 0:31 I. r A

Hydrographic Data from the Pilot Study of the Coastal Transition Zone (CTZ) Program, 17-26 March 1987

DTIC Science & Technology

1989-01-30

C- o C! -0 0 0 -4i 104 Wz 0 4 P, N. *40 #A -*0 9*4 14 -*40s on f I046.. I 4n in f" *l eq r,4 "I CA 0~ 0 ~ 4 i 0 ~1 0 00 Va 4 n !=4 O .." VV " Ka ...97331 Dr. Robert L. Smith 1 Dr. Adriana Huyer I Dr. P. Michael Kosro 1 Dr. Mark R. Abbott I Dr. John S. Allen 1 Dr. Tim Cowles 1 Dr. David Kadco i Dr. Ted

Ultraviolet Lasing Transitions in Diatomic Molecules

DTIC Science & Technology

1980-01-01

N N CU co Nm N U) 0 𔃺 0 v4 40 0 M.- 4) LA 𔃺 N , Oh W N OhN 0 N ’ ) ’ (4 LA 0n Oh N 0 U) N \\0 Lm 𔃺 N \\0 P % r- r- C4 m 4 -4 -4 q 0 0 -4...calculations indicate 0 20 U,ot 10 2 p I I p0 Fig. ll. TIME (10 ඉ) Pi Ola aba for N , C-8 Mba. at 33"I A. ezefed in sir a 14 roT pmwie by (a) Modd BD0 mi (b...state is now commonly called the B state by experimentalists. Simple considerations suggest that both this

Prime Contract Awards by FSC/SVC and Purchasing Office in Excess of $100,000. FY 1992 (1005 Guns thru 30 mm -- 8130 Reels and Spools)

DTIC Science & Technology

1993-01-01

gn -*( 0Q 0 00 N 40 a a:wo to00)0 . C4 L~.4 U.U.L f6 - 1 -l 00o.00 4 Cfl4 mlC4 P. q w-i N4 r- Z-i (A N f 6-0 -IIn 4c (A (fl i N r- -I .4 C4 w-4 (no 00...V40& X U -- C -- 0. - =: z 0.V 4L CLO U U .4 .4U isQ3t lb 4. Cl . c൰VLSC io&C -4 CL > . 0O ACCa I.- (A-1.. S4 It ;: 0 0 04 06 > t I .. C ..4 0 o 1

Land Management Alternatives in the Lake Erie Drainage Basin.

DTIC Science & Technology

1979-03-01

NIB I’ ZhI N a I42 U. ... . " w °A 1 B 1 -A - a4 I B Ck hJ O I / I I ki w I o 0D o • o 0* B B ** .- - Cm Il sD + I rI I tv : LO S A z z 0 0n I o1 I N...4’A SO .Ato C~ Stall - Na.. CaCAO t-.a QC’s Ceaaa a.aa.a Dn..a * 0- - o a.av..aa.-aC, c - a a - 0 a~ S - 0 Uct.toajaO - to. - N C at a -a Ca :a...46 N. 9 . 34.8 0 1 O W"ൈ ftN de a .4 nS Sa o 0 -SIWO * 0 LiS . -’ AL 4Wf w . IS v z -wa u t fm 1- 0, M Is -. 1 , U h.S 84 C: I It C a.. W. o IL 40

Neuroprosthetics and Solutions for Spinal Cord Dysfunctions

DTIC Science & Technology

2012-08-01

SSNI. 0 1 2 3 4 5 60 0.2 0.4 0.6 0.8 1 Stimulus amplitude (µA) P( rec rui tin g a t le ast n ne uro ns ) P(n=0|I) P(n=1|I) P(n=2|I) P(n=3|I) P(n=4|I...Annual Fall Meeting. Los Angeles, CA: 2007. 15 Bourbeau DJ, Hokanson J, Weber DJ. (2008). A computational model for examining activation of peripheral

Seawater Hydraulics: Development and Evaluation of an Experimental Diver Tool System.

DTIC Science & Technology

1984-02-01

wrench was operated, it ran irregularly and with low power; third, the motor would not always tart when the valve was actuated . Investigation revealed...I’’r Iulticctlic.4X N (4M144 i , I1.401 . (L(It I A,-- II N1I I I \\k RI Cit I X I)H ( 4 Wit IN ( N I (41lnson. XXaisli,, iot , D)4 NI I M4 I lid. Ill...its primary distribution lists. SUBJECT CATEGORIES 28 ENERGY/POWER GENERATION 29 Thermal conservation (thermal engineering of buildings. HVAC I SHORE

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 8. (General Contractor, Inc.-H and H Industrial Instruments)

DTIC Science & Technology

1989-01-01

4C>Qa0 QQ aQD1> 4 0-4 - 4 - 4-o4 - 4 - 4->Q0 o00 > > > Cell . 0c4 IC1 l’(0< 40 I O O O O O O O O O O O O O O O O O O O (n3IU 1 m C𔃾 11.0 C3 xO O O O O...In it el4 យ C-4 il.J 4 44 4 4 4 44 4 4 4 X"""NI (D00)0) 000 (0 (04C) 1 U0I co-4 1I N4 4 4 4 4 44 4 4 4 r44 QNO 40 m NQ Is .1 II 0-4 11 0 0 0 0 00 0 0...C C II C0 1- 0 1- 11 to I MN 11 - 1-4 iil Wcs n z 2 i Z - I WNC 110010>C 20 C O>l 0 a 2 - 0- Oil El4 eJ 1140 1- 0 C’ I-i-i c Il linN - I it4 ". z - I

Comparative Study of the Effect of Defects on Selective Adsorption of Butanol from Butanol/Water Binary Vapor Mixtures in Silicalite-1 Films

DOE PAGES

Farzaneh, Amirfarrokh; DeJaco, Robert F.; Ohlin, Lindsay; ...

2017-08-02

A promising route for sustainable 1-butanol (butanol) production is ABE (acetone, butanol, ethanol) fermentation. However, recovery of the products is challenging because of the low concentrations obtained in the aqueous solution, thus hampering large-scale production of biobutanol. Membrane and adsorbent-based technologies using hydrophobic zeolites are interesting alternatives to traditional separation techniques (e.g., distillation) for energy-efficient separation of butanol from aqueous mixtures. To maximize the butanol over water selectivity of the material, it is important to reduce the number of hydrophilic adsorption sites. This can, for instance, be achieved by reducing the density of lattice defect sites where polar silanol groupsmore » are found. The density of silanol defects can be reduced by preparing the zeolite at neutral pH instead of using traditional synthesis solutions with high pH. In this work, binary adsorption of butanol and water in two silicalite-1 films was studied using in situ attenuated total reflectance–Fourier transform infrared (ATR-FTIR) spectroscopy under equal experimental conditions. One of the films was prepared in fluoride medium, whereas the other one was prepared at high pH using traditional synthesis conditions. The amounts of water and butanol adsorbed from binary vapor mixtures of varying composition were determined at 35 and 50 °C, and the corresponding adsorption selectivities were also obtained. Both samples showed very high selectivities (100–23 000) toward butanol under the conditions studied. The sample having low density of defects, in general, showed ca. a factor 10 times higher butanol selectivity than the sample having a higher density of defects at the same experimental conditions. This difference was due to a much lower adsorption of water in the sample with low density of internal defects. Analysis of molecular simulation trajectories provides insights on the local selectivities in the zeolite channel network and at the film surface.« less

Comparative Study of the Effect of Defects on Selective Adsorption of Butanol from Butanol/Water Binary Vapor Mixtures in Silicalite-1 Films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farzaneh, Amirfarrokh; DeJaco, Robert F.; Ohlin, Lindsay

A promising route for sustainable 1-butanol (butanol) production is ABE (acetone, butanol, ethanol) fermentation. However, recovery of the products is challenging because of the low concentrations obtained in the aqueous solution, thus hampering large-scale production of biobutanol. Membrane and adsorbent-based technologies using hydrophobic zeolites are interesting alternatives to traditional separation techniques (e.g., distillation) for energy-efficient separation of butanol from aqueous mixtures. To maximize the butanol over water selectivity of the material, it is important to reduce the number of hydrophilic adsorption sites. This can, for instance, be achieved by reducing the density of lattice defect sites where polar silanol groupsmore » are found. The density of silanol defects can be reduced by preparing the zeolite at neutral pH instead of using traditional synthesis solutions with high pH. In this work, binary adsorption of butanol and water in two silicalite-1 films was studied using in situ attenuated total reflectance–Fourier transform infrared (ATR-FTIR) spectroscopy under equal experimental conditions. One of the films was prepared in fluoride medium, whereas the other one was prepared at high pH using traditional synthesis conditions. The amounts of water and butanol adsorbed from binary vapor mixtures of varying composition were determined at 35 and 50 °C, and the corresponding adsorption selectivities were also obtained. Both samples showed very high selectivities (100–23 000) toward butanol under the conditions studied. The sample having low density of defects, in general, showed ca. a factor 10 times higher butanol selectivity than the sample having a higher density of defects at the same experimental conditions. This difference was due to a much lower adsorption of water in the sample with low density of internal defects. Analysis of molecular simulation trajectories provides insights on the local selectivities in the zeolite channel network and at the film surface.« less

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 88. Part 9. (Giusti & Renshaw Construction-Hitachi America, Ltd.)

DTIC Science & Technology

1988-01-01

0000000000000-4-4 00 C-0 C- 0 0 Mol040 9L0 I c0N IW00000000110N00O X"- wo Ci 0 izo-4 ( 0KI o WI(0ON 0 0 C4 C-C-C-C-C-C-C-L9CC-0 C-I.- OC- 0 C-LI 0001...I r- r- rl r- r- o to V -* q1t v -4 -9t -4 Ln Ln Ln Ln 0 1 wotn< I N N C,4 N -4 Ln Ln -4 V 14 -4 -4 -4 00 Lf) U) Ul) Ln I CO a c) 1 -4 04 0) -e 0) tD

Properties of Aircraft Fuels and Related Materials.

DTIC Science & Technology

1991-07-29

LA . 0I Z La u0I Z4 Li LA . L U) a:L) mi F- - L Wz N ) Mtwm Li La . N t o) a f) r en f" ’m, Mww 4v Nv NuQe...mo 000) 0 100 U4v4U1 w 70 w n(~xI I ! I- I I iI I i I I I I Ii I I I " LJLaJ La . LaJLI 0 0 L.. ao . 0 .L 0 EL 17z U. Z IV CD 0 Iqx 0 1 O0 cN.. 10. In...notice on a specific document. INCLASSIFIED ECURITY CLASSIFICATION OF THIS PAGE IForm Approved REPORT DOCUMENTATION PAGE MB No, 0704-0188 la .

Word Criticality Analysis. MOS: 67N. Skill Levels 1 & 2

DTIC Science & Technology

1981-09-01

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Baseline Noise Measurements at Vandenberg AFB, California.

DTIC Science & Technology

1988-01-01

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Prime Contract Awards by State or Country, Place and Contractor. Part 11 (Gibbsboro Air Force Station, New Jersey - Peekskill, New York), FY1991

DTIC Science & Technology

1991-01-01

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All Prime Contract Awards by State or Country, Place and Contractor. Part 1. (Alexander City, Alabama-Sevier, Arkansas)

DTIC Science & Technology

1989-01-01

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Vibration and Temperature Survey Production AH-1G Helicopter

DTIC Science & Technology

1974-03-01

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Protective Immunogenicity of Group A Streptococcal M-Related Proteins

PubMed Central

Niedermeyer, Shannon E.; Agbaosi, Tina; Hysmith, Nicholas D.; Penfound, Thomas A.; Hohn, Claudia M.; Pullen, Matthew; Bright, Michael I.; Murrell, Daniel S.; Shenep, Lori E.; Courtney, Harry S.

2015-01-01

Many previous studies have focused on the surface M proteins of group A streptococci (GAS) as virulence determinants and protective antigens. However, the majority of GAS isolates express M-related protein (Mrp) in addition to M protein, and both have been shown to be required for optimal virulence. In the current study, we evaluated the protective immunogenicity of Mrp to determine its potential as a vaccine component that may broaden the coverage of M protein-based vaccines. Sequence analyses of 33 mrp genes indicated that there are three families of structurally related Mrps (MrpI, MrpII, and MrpIII). N-terminal peptides of Mrps were cloned, expressed, and purified from M type 2 (M2) (MrpI), M4 (MrpII), and M49 (MrpIII) GAS. Rabbit antisera against the Mrps reacted at high titers with the homologous Mrp, as determined by enzyme-linked immunosorbent assay, and promoted bactericidal activity against GAS emm types expressing Mrps within the same family. Mice passively immunized with rabbit antisera against MrpII were protected against challenge infections with M28 GAS. Assays for Mrp antibodies in serum samples from 281 pediatric subjects aged 2 to 16 indicated that the Mrp immune response correlated with increasing age of the subjects. Affinity-purified human Mrp antibodies promoted bactericidal activity against a number of GAS representing different emm types that expressed an Mrp within the same family but showed no activity against emm types expressing an Mrp from a different family. Our results indicate that Mrps have semiconserved N-terminal sequences that contain bactericidal epitopes which are immunogenic in humans. These findings may have direct implications for the development of GAS vaccines. PMID:25630406

All Prime Contract Awards by State or Country, Place, and Contractor. Part 16 (Albany Oregon-Newport Rhode Isld)

DTIC Science & Technology

1990-01-01

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Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 4 (Better Insulation Services - CSP Inc)

DTIC Science & Technology

1990-01-01

0 )> 0 ) N o NOa (aP 403 5 4101, .M-I i ) W) Lu.J %" w0) WM0 Ili00 wa M 0 woo) wm w ) U. 00 CC L-00 *ILA M(-4 M6(D( (0In (-4 ( 0 ( (04 M- In (0t 0 ( 0 ...40000000000 00 I(-4N iI , 0 iti -wC) N -4 r- r- t>- NZM ɜ -01 ( 0 I n n( CO l 0 In 0 M U 5 ( 0 -40 F (*2 11 -422* nz w2Z* -422.z -%c 222222222222zz IO 0 ...P010 Itu 1-. ao 00 0 *- 044 -4n ( 0 (0w0( 0 ( 0 ( 0 ( 0 (00( 0 (

Snohomish Estuary Wetlands Study Volume III. Classification and Mapping

DTIC Science & Technology

1978-07-01

Marine plant communities form the basis for some of the most complex i food webs known to man. Because of their complexity any destruction of these plant... NCV ) Ř fv;1 4 CV r% . coI * ".444 Ř m- 0mf n4 ~ ’ oC- . -4c C4 C CJL t o% P o I-""C4enc n S qw qt "* *n *nL P o% 0zwk oU a "C-4 2 C" Iv3gMNIV~ I.z -I

Synthesis and Characterization of a Series of Structurally and Electronically Diverse Fe(II) Complexes Featuring a Family of Triphenylamido-Amine Ligands

PubMed Central

Paraskevopoulou, Patrina; Ai, Lin; Wang, Qiuwen; Pinnapareddy, Devender; Acharyya, Rama; Dinda, Rupam; Das, Purak; Çelenligil-Çetin, Remle; Floros, Georgios; Sanakis, Yiannis; Choudhury, Amitava; Rath, Nigam P.; Stavropoulos, Pericles

2009-01-01

A family of triphenylamido-amine ligands of the general stoichiometry LxH3 = [R-NH-(2-C6H4)]3N (R = 4-t-BuPh (L1H3), 3,5-t-Bu2Ph (L2H3), 3,5-(CF3)2Ph (L3H3), CO-t-Bu (L4H3) 3,5-Cl2Ph (L5H3), COPh (L6H3), CO-i-Pr (L7H3), COCF3 (L8H3), i-Pr (L9H3)) has been synthesized and characterized, featuring a rigid triphenylamido-amine scaffold and an array of stereoelectronically diverse aryl, acyl and alkyl substituents (R). These ligands are deprotonated by potassium hydride in THF or DMA and reacted with anhydrous FeCl2 to afford a series of ferrous complexes, exhibiting stoichiometric variation and structural complexity. The prevalent [(Lx)Fe(II)–solv]− structures (Lx = L1, L2, L3, L5, solv = THF; Lx = L8, solv = DMA; Lx = L6, L8, solv = MeCN), reveal a distorted trigonal bipyramidal geometry, featuring ligand-derived [N3,amidoNamine] coordination and solvent attachment trans to the Namine atom. Specifically for [(L8)Fe(II)–DMA]−, an Namido residue is coordinated as the corresponding Nimino moiety (Fe–N(Ar)=C(CF3)–O−). In contrast, compounds [(L4)Fe(II)] −, [(L6)2Fe(II)2]2−, [K(L7)2Fe(II)2]22− and [K(L9)Fe]2 are all solvent-free in their coordination sphere and exhibit four-coordinate geometries of significant diversity. In particular, [(L4)Fe(II)]− demonstrates coordination of one amidato residue via the O-atom end (Fe–O–C(t-Bu)=N(Ar)). Furthermore, [(L6)2Fe(II)2]2− and [K(L7)2Fe(II)2]22− are similar structures exhibiting bridging amidato residues (Fe–N(Ar)–C(R)=O–Fe) in dimeric structural units. Finally the structure of [K(L9)Fe]2 is the only example featuring a minimal [N3,amidoNamine] coordination sphere around each Fe(II) site. All compounds have been characterized by a variety of physicochemical techniques, including Mössbauer spectroscopy and electrochemistry, to reveal electronic attributes that are responsible for a range of Fe(II)/Fe(III) redox potentials exceeding 1.0 V. PMID:19950956

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 11. (Kalidescope Shipping, Inc.-Lous Electronics)

DTIC Science & Technology

1989-01-01

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The impact of hydroquinone on acetylcholine esterase and certain human carbonic anhydrase isoenzymes (hCA I, II, IX, and XII).

PubMed

Scozzafava, Andrea; Kalın, Pınar; Supuran, Claudiu T; Gülçin, İlhami; Alwasel, Saleh H

2015-12-01

Carbonic anhydrases (CAs) are widespread and the most studied members of a great family of metalloenzymes in higher vertebrates including humans. CAs were investigated for their inhibition of all of the catalytically active mammalian isozymes of the Zn(2+)-containing CA, (CA, EC 4.2.1.1). On the other hand, acetylcholinesterase (AChE. EC 3.1.1.7), a serine protease, is responsible for ACh hydrolysis and plays a fundamental role in impulse transmission by terminating the action of the neurotransmitter ACh at the cholinergic synapses and neuromuscular junction. In the present study, the inhibition effect of the hydroquinone (benzene-1,4-diol) on AChE activity was evaluated and effectively inhibited AChE with Ki of 1.22 nM. Also, hydroquinone strongly inhibited some human cytosolic CA isoenzymes (hCA I and II) and tumour-associated transmembrane isoforms (hCA IX, and XII), with Kis in the range between micromolar (415.81 μM) and nanomolar (706.79 nM). The best inhibition was observed in cytosolic CA II.

Mother-Child Book-Sharing and Children's Storytelling Skills in Ethnically Diverse, Low-Income Families

ERIC Educational Resources Information Center

Luo, Rufan; Tamis-LeMonda, Catherine S.; Kuchirko, Yana; Ng, Florrie F.; Liang, Eva

2014-01-01

The present study examined book-sharing interactions between mothers and their 4-year-old children from African American (n?=?62), Dominican (n?=?67), Mexican (n?=?59) and Chinese (n?=?82) low-income U.S. families, and children's independent storytelling skills one year later. Mothers' book-sharing style was analysed in terms of…

Prime Contract Awards by State or Country, Place and Contractor. Part 16 (Fort Hill, Virginia - Chesapeake, Virginia), FY1991

DTIC Science & Technology

1991-01-01

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The antisocial family tree: family histories of behavior problems in antisocial personality in the United States.

PubMed

Vaughn, Michael G; Salas-Wright, Christopher P; DeLisi, Matt; Qian, Zhengmin

2015-05-01

Multiple avenues of research (e.g., criminal careers, intergenerational family transmission, and epidemiological studies) have indicated a concentration of antisocial traits and behaviors that cluster among families and within individuals in a population. The current study draws on each of these perspectives in exploring the intergenerational contours of antisocial personality disorder across multiple generations of a large-scale epidemiological sample. The analytic sample of persons meeting criteria for antisocial personality disorder (N = 1,226) was derived from waves I and II of the National Epidemiologic Survey on Alcohol and Related Conditions. Path analytic, latent class, and multinomial models were executed to describe and elucidate family histories among persons diagnosed with antisocial personality disorder. Three classes of an antisocial family tree were found: minimal family history of problem behaviors (70.3 % of sample) who were characterized by higher socioeconomic functioning, parental and progeny behavior problems (9.4 % of sample) who were characterized by criminal behaviors, psychopathology, and substance use disorders, and multigenerational history of problem behaviors (20.3 % of sample) who were characterized by alcoholism, psychopathology, and versatile criminal offending. These findings add a typology to intergenerational studies of antisocial behavior that can assist in identifying etiological and treatment factors among those for whom crime runs in the family.

All Prime Contract Awards by State or Country, Place and Contractor. Part 10. (Abington, Massachusetts-Zeeland, Michigan)

DTIC Science & Technology

1989-01-01

IOOOOON ᝰ WO) 40L L i LLJ 14 M -4 :: 347 )0( 0 ix 4(0 0.70 4z0(0) 0 0 co L(0 M00 0)L’ 00 (0.- 4 0.4 of4C 00000 IO0 00 00 00 w00 0000 0000 0’) 00 00 0000 V...82174mw-*0 N"’- -4N CO NOWO MINIM) m’,4mmw0 -400 mmC’ -4N-401U1 LA ON I 0)00 It :) C 000 If aHc CO0 a* I N. U I moo0 It IL Q M 00 (11 1 I 00- if I H4 0

Design and Real-Time Implementation of a Baseband LPC Coder for Speech Transmission over 9600 BPS Noisy Channels. Volume II. Programming Listings.

DTIC Science & Technology

1980-02-01

cwc N (w~ mm. IDmm m w. C. msite &C-ew %a~m MCI I Di . m1a.2 ,% v oa m.1] W.k1i . . 13.M mmm r, q.W.3.44. I&1242 %D2 1.J1 M.1. ItP a b nNM - f .M2 47 4...a a a a a.a a.a0 IBM a aa a11,11 a .0 a1 . U q M4 MS K IaI u C% A4 U u0 1. w4 . N MKV Ia IO1 U a,". 44 4 .4 N m N N N N N6 N N N (M M M M U M M M CD

Structure and stability of the finite-area von Kármán street

NASA Astrophysics Data System (ADS)

Luzzatto-Fegiz, Paolo; Williamson, Charles H. K.

2012-06-01

By using a recently developed numerical method, we explore in detail the possible inviscid equilibrium flows for a Kármán street comprising uniform, large-area vortices. In order to determine stability, we make use of an energy-based stability argument (originally proposed by Lord Kelvin), whose previous implementation had been unsuccessful in determining stability for the Kármán street [P. G. Saffman and J. C. Schatzman, "Stability of a vortex street of finite vortices," J. Fluid Mech. 117, 171-186 (1982), 10.1017/S0022112082001578]. We discuss in detail the issues affecting this interpretation of Kelvin's ideas, and show that this energy-based argument cannot detect subharmonic instabilities. To find superharmonic instabilities, we employ a recently introduced approach, which constitutes a reliable implementation of Kelvin's stability ideas [P. Luzzatto-Fegiz and C. H. K. Williamson, "Stability of conservative flows and new steady fluid solutions from bifurcation diagrams exploiting a variational argument," Phys. Rev. Lett. 104, 044504 (2010), 10.1103/PhysRevLett.104.044504]. For periodic flows, this leads us to organize solutions into families with fixed impulse I, and to construct diagrams involving the flow energy E and horizontal spacing (i.e., wavelength) L. Families of large-I vortex streets exhibit a turning point in L, and terminate with "cat's eyes" vortices (as also suggested by previous investigators). However, for low-I streets, the solution families display a multitude of turning points (leading to multiple possible streets, for given L), and terminate with teardrop-shaped vortices. This is radically different from previous suggestions in the literature. These two qualitatively different limiting states are connected by a special street, whereby vortices from opposite rows touch, such that each vortex boundary exhibits three corners. Furthermore, by following the family of I = 0 streets to small L, we gain access to a large, hitherto unexplored flow regime, involving streets with L significantly smaller than previously believed possible. To elucidate in detail the possible solution regimes, we introduce a map of spacing L, versus impulse I, which we construct by numerically computing a large number of steady vortex configurations. For each constant-impulse family of steady vortices, our stability approach also reveals a single superharmonic bifurcation, leading to new families of vortex streets, which exhibit lower symmetry.

Work-family conflict and enrichment from the perspective of psychosocial resources: comparing Finnish healthcare workers by working schedules.

PubMed

Mauno, Saija; Ruokolainen, Mervi; Kinnunen, Ulla

2015-05-01

We examined work-family conflict (WFC) and work-family enrichment (WFE) by comparing Finnish nurses, working dayshifts (non-shiftworkers, n = 874) and non-dayshifts. The non-dayshift employees worked either two different dayshifts (2-shiftworkers, n = 490) or three different shifts including nightshifts (3-shiftworkers, n = 270). Specifically, we investigated whether different resources, i.e. job control, managers' work-family support, co-workers' work-family support, control at home, personal coping strategies, and schedule satisfaction, predicted differently WFC and WFE in these three groups. Results showed that lower managers' work-family support predicted higher WFC only among 3-shiftworkers, whereas lower co-workers' support associated with increased WFC only in non-shiftworkers. In addition, shiftworkers reported higher WFC than non-shiftworkers. However, the level of WFE did not vary by schedule types. Moreover, the predictors of WFE varied only very little across schedule types. Shiftwork organizations should pay more attention to family-friendly management in order to reduce WFC among shiftworkers. Copyright © 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1985. Part 7 (Electronic Methods Assoc - Freshour Construction Co Inc).

DTIC Science & Technology

1985-01-01

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Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Oank8 Elbelco Inc. - Food Service Decor & Design). Part 7

DTIC Science & Technology

1994-03-01

In = 4j 1 wow 11 (A com L) w U U) 04 ý4 0 u Ce ý4 0 0 Cie 0 Ix rý 00 .4 L) cc W 0 N C I cc" If x Q-J(Doý- x q1t (D 0 xooooý-- 0 L) 0 0 ý- CL. 0 m Ln...oCGoCOCO CON CN w 4 < 0 44 < O44 M -cvMN U (COO0-40(11 .-40 -40 OCOCCID(O 040 00W 04 NU) COM -i -444 0 N 0-4 if U.. a: a Ezz Z z 0 In0 000 a CV (0() 3n U4... coM 4)(4W-4 sN UN u m 4 - W gn N I 004- If > tcI Ny.4 -4 of0 X.4 cc (a 000000000001111111111Q0 N a I 004o- N1 as 4- -40-4 .4 -4 0 No tl 00 0

All Prime Contract Awards by State or Country, Place, and Contractor. Part 8 (La Grange Illinois-Wichita, Kansas)

DTIC Science & Technology

1990-01-01

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Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Claude Ralph - Day Francis O Co. Inc.)

DTIC Science & Technology

1994-03-01

4LLAA ( LU AC x 0 m LA (LA 0 x1 (1A)LALLCA(A( AcCA L A 0 ( tALALA01upIc (00.- U1 C(0 (D0 (0’.CD(0 (D (D (D (DW 00 0 (m (m (0CD(D0(m0w(0(20 (D0w Lo(1(0...COVcII N 44444444444 4444444444 N c04 II 44 4444 N 0041 caoacao acca 0i 0o cn I’ ID6 OOCNY 2 N4NrJNNNNNN0 NNNNNNNNNN C3 cO-4 11 L) U0 0 0 0 0 0c 0 0 0 0...0.4 .. 14൰*o0oo 00 0 0 - .4 N 4j H 4 I0cc WOO 004 INN C 10 10 100N04144443(300 t0 I0.4 ffM MN 14 100 N 0YMIn C 0 0 (1 H ma I (fl>( IIO N N NN N 0 4

A Latent Profile Analysis of Latino Parenting: The Infusion of Cultural Values on Family Conflict

PubMed Central

Ayón, Cecilia; Williams, Lela Rankin; Marsiglia, Flavio F.; Ayers, Stephanie; Kiehne, Elizabeth

2015-01-01

The purpose of the present study was to (a) examine how acculturation and social support inform Latinos’ parenting behaviors, controlling for gender and education; (b) describe parenting styles among Latino immigrants while accounting for cultural elements; and (c) test how these parenting styles are associated with family conflict. A 3 step latent profile analysis with the sample (N = 489) revealed best fit with a 4 profile model (n = 410) of parenting: family parenting (n = 268, 65%), child-centered parenting (n = 68, 17%), moderate parenting (n = 60, 15%), and disciplinarian parenting (n = 14, 3%). Parents’ gender, acculturation, and social support significantly predicted profile membership. Disciplinarian and moderate parenting were associated with more family conflict. Recommendations include integrating culturally based parenting practices as a critical element to family interventions to minimize conflict and promote positive youth development. PMID:26966343

High Efficiency, Low Power Thermoelectric Coolers.

DTIC Science & Technology

1979-01-01

NA~ 2 1128- ak ~iI I " N --- -- ... .I S/ I’ 7 I fir- 114 -- ; I ’ I J tf1 NN N .’i M i 29 MOM___I p ~p. .* S S I I Ii N *0 - i. - -i - -Y...compression seal. 3.4.2 Evacuate tube. 3.4.3 Close off vacuum valve after thirty minutes. 3.4.4 With the torch, carefully melt the contents of the tube...tube of material is cool enough to hold with the hand, close vacuum valve and use the torch to seal the tube about 2 inches above the top of the

Dredging Operations Technical Support Program. Mathematical Model of the Consolidation/Desiccation Processes in Dredged Material.

DTIC Science & Technology

1985-07-01

5695 BF(I) - BETA(LDF) * GOTO 7 5700 6 NN - N-i 5705 Ch - CI / (ES(N)-ES(NN)) 5710 AF(I) w ALPHA(N) + CM*(ALPHA(N)-ALPHA(NN)) 5715 DF(I) a BETA(N) 4...1OXP34t4SETTLEMENT DUE TO CONSOLIDATION - PF1O.4) 7845 113 FORMAT(/1OX932HSETTLEMENT DUE TO DESICCATION - PF1O.4) 7850 114 FORNAT(/1OX920HSURFACE

Dollar Summary of Prime Contract Awards by State, Place, and Contractor. Part 3 (Adrian, Michigan-Yamhill, Oregon)

DTIC Science & Technology

1989-01-01

oi ii VIc - w : < Ŕ- z I 00UL. 0 (0 C~0ə in 1r~- 0 "n af 011< 0-4 X" x 21u < o .- w j ( C )W 40 L ac iFD "IU Z W Q x 14 jw w 9L~~~ I ( -G AZZ" j 0...00 0 0 0J 0- 3- a& 0 ~~ Cc Cc Cc w-l- Cc- 1. 1 09 ac1’ 1’- 00 ac - aF - 0n I I I l))0 In 01 41 CF ’ 0 0 I -II Y . 00 I I I I 44 I I--I IL I (a 4l In...z 0n / I I b 4 < 4I(-0- ( w40 -K - no . . o1 m In oNC)C -4 -41 -4 I Z 0 " w NM N N. z) IjC mU CZt 0 m " I ZU00 r .NI-0MU) E 00) 0ww w I 0 0 xfmL"j

Assessment of association of D3 dopamine receptor MscI polymorphism with schizophrenia: Analysis of symptom ratings, family history, age at onset, and movement disorders

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gaitonde, E.J.; Mollon, J.D.; McKenna, P.J.

Several studies have reported an association between schizophrenia and homozygosity for the MscI restriction site in exon 1 of the D3 dopamine receptor gene, but other studies have failed to find this association. Recent reports have suggested that the association is most salient in male patients with a family history of schizophrenia. We examined this restriction site in a group of schizophrenic patients (n = 84) and in normal controls (n = 77). Patients were subdivided according to demographic and clinical features, particular attention being paid to movement disorders. No significant difference in allelic or genotypic distribution was seen betweenmore » the two groups. No association was seen between homozygosity and a positive family history, age at onset of illness, clinical subtype, negative symptom score, or movement disorder scores. 33 refs., 2 tabs.« less

How Parents Describe Picky Eating and Its Impact on Family Meals: A Qualitative Analysis

PubMed Central

Trofholz, Amanda C.; Schulte, Anna K.; Berge, Jerica M.

2016-01-01

Children are frequently described as being picky eaters. However, this term has been inconsistently defined in prior research. There is limited qualitative research data investigating how parent’s define picky eating, how they respond to it, or how they see picky eating impacting their child’s dietary intake or the family meal. For this study, parents (n=88) of siblings (ages 2–18 years old) were interviewed in their homes. The semi-structured interviews focused on parent feeding practices and child eating behaviors. A qualitative content analysis approach was used to analyze the data; themes regarding picky eating emerged. Results of this study show that the majority of parents (94% female; mean age 35 years) were from minority and low income homes. The following themes regarding picky eating were identified: 1) children were frequently described as being picky eaters; 2) parents defined picky eating in a variety of ways (i.e., not liking a few foods; limited intake; resisting texture or appearance of foods; resistance to new foods); 3) picky eating impacts the family meal (i.e., promotes meal-related parent stress; impacts meal preparation); and 4) parents respond to picky eating in a variety of ways (i.e., require child tries food; allow child to make separate meal; allow child not to eat; parent makes a separate meal; allows child to choose only food he/she likes; requires child to eat anyway). This study demonstrates that many parents experience child picky eating and report that it impacts family meals. It provides information on the specific ways pickiness impacts the family meal and how parents respond to pickiness. This study also provides guidance for future studies wishing to define picky eating or evaluate the prevalence of child pickiness. PMID:27889496

How parents describe picky eating and its impact on family meals: A qualitative analysis.

PubMed

Trofholz, Amanda C; Schulte, Anna K; Berge, Jerica M

2017-03-01

Children are frequently described as being picky eaters. However, this term has been inconsistently defined in prior research. There is limited qualitative research investigating how parent's define picky eating, how they respond to it, or how they see picky eating impacting their child's dietary intake or the family meal. For this study, parents (n = 88) of siblings (ages 2-18 years old) were interviewed in their homes. The semi-structured interviews focused on parent feeding practices and child eating behaviors. A qualitative content analysis approach was used to analyze the data; themes regarding picky eating emerged. Results of this study show that the majority of parents (94% female; mean age 35 years) were from minority and low income homes. The following themes regarding picky eating were identified: 1) children were frequently described as being picky eaters; 2) parents defined picky eating in a variety of ways (i.e., not liking a few foods; limited intake; resisting texture or appearance of foods; resistance to new foods); 3) picky eating impacted the family meal (i.e., promotes meal-related parent stress; impacts meal preparation); and 4) parents responded to picky eating in a variety of ways (i.e., require child tries food; allow child to make separate meal; allow child not to eat; parent makes a separate meal; allows child to choose only food he/she likes; requires child to eat anyway). This study demonstrates that many parents experience child picky eating and report that it impacts family meals. Additionally, study results provide information on the specific ways pickiness impacts the family meal and how parents respond to pickiness. This study also provides guidance for future studies wishing to define picky eating or evaluate the prevalence of child pickiness. Copyright © 2016 Elsevier Ltd. All rights reserved.

Military Families with Handicapped Children: The Reassignment Problem

DTIC Science & Technology

1981-02-01

of them ( education service center, Lub- bock Medical facilities , Lubbock State School, psychiatric facilities , etc.) 18. Additional comments: Rapidly...Attached DD ) AN 73 1473 EDITION OF I NOV6GS IS OBSOLETE UNCL 23 Oct 81 8 1 10 2oc 0 6 2 !CURITY CLASSIFICATION OF THIS PAGE (I7,n Data Entered) AIR WAR...COLLEGE AIR UNIVERSITY Report No. MS107-81 MILITARY FAMILIES WITH HANDICAPPED CHILDREN: THE REASSIGNMENT PROBLEM (A (WiDE TO SPECIAL EDUCATION AVAILABLE

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 7 (Delta Engineering Services - Electronic Design Engr)

DTIC Science & Technology

1990-01-01

M m CV) In4 4 m -nW nmU I C4 innonn 02-40 o . M 1 Ŝ if f8 r- r-4 -V ,MT "f.mmt ,m -P - .I)t )o I Mf *in 040 if -P4-m MI N--4-4-4- PI rI.PP NN 4 0 r...4 U000 0 4 NIO G0.0 se f8 a0 ag0l 000 w00 0040 00c OD 0W040o4O EW 1U-4 £a Oo* -Q4.4 100 040 COO31 00n 00313 00 0-0,0- $.-a£ 40-1 a Uls. 0 0 .4-4 M NN...01.4 0 3 .40iM16t-00t-40.-4 OW 0dM’ t& 0r 0 8o acCa 0 a o o E00 1,12 0008-4 .4 00 0(0A - 3: 60 1 000 00 00 00 0 V0 ( A 1.-*S~ Z.-0N0 -I 0N 4N A)w 0

Metal-Arc Welded Ti-6Al-4V, Ti-4Al-4V, and Ti-5Al-2 and 1/2 SN Titanium Alloys

DTIC Science & Technology

1959-05-01

x . 7 8 8 - x 2 . 1 2 i n c h ) V n o t c h Charpy i m p a c t spec imen . MATERIALS COHN* .25 . 2 3 The m a t e r i a l s u s e d d...i e d V n o t c h Charpy i m p a c t spec imen i n a s t a n d a r d i m p a c t machine w i th anvi l s modified so t h a t the center...of percussion of the pendulum coincided with the center of the impact specimen, This FIGURE 3: SUBSIZE T E N S I L E SPECIMEN FIGURE 4

A new determination of the primordial helium abundance

NASA Astrophysics Data System (ADS)

Peimbert, M.; Peimbert, A.; Luridiana, V.

2017-07-01

We present new Y values for five H II regions, from these values we determine the primordial helium abundance, YP, and obtain that YP = 0.2446 ± 0.0029, (Peimbert, A. et al. 2016, RMxAA, 52, 419). The main difference of our new value with the YP value by Peimbert, M. et al. (2007, ApJ , 666, 633) is due to the use of updated atomic physics parameters. Our YP value is consistent with that by Aver, E. et al. (2015, JCAP, 7, 11), that amounts to YP = 0.2449 ± 0.0040, but in disagreement by more than 3σ with that by Izotov, Y. I. et al. (2014, MNRAS, 443, 778), that amounts to YP = 0.2551 ± 0.0022. YP together with Big Bang Nucleosynthesis, BBN, can be used to put constraints on the number of neutrino families, Nν, and the neutron mean life, τn. The adoption of a neutron mean life of τn = 880.3 ± 1.1 (s) (Olive, K. A et al. 2014, Chinese Physics C, 38, 090001) and our YP value imply that Neff = 2.90 ± 0.22, consistent with 3 neutrino families but not with 4 neutrino families. The adoption of Neff = 3.046 (Mangano, G. and Serpico, P. D. 2011, PhLB, 701, 296) and our YP value imply that τn = 872 ± 14 (s), consistent with both high and low values of τn in the literature. An increase on the quality of the YP determination from H II regions will provide stronger constraints on the Nν and τn values.

A codon-usage variant in the (GGN){sub n} trinucleotide polymorphism of the androgen receptor gene as an aid in the prenatal diagnosis of ambiguous genitalia due to partial androgen insensitivity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lumbroso, R.; Vasiliou, M.; Beitel, L.K.

1994-09-01

Exon 1 at the X-linked androgen receptor (AR) locus encodes an N-terminal modulatory domain that contains two large homopolyamino acid tracts: (CAG;glutamine;Gln){sub 11-33} and (GGN;Glycine;Cly){sub 15-27}. Certain AR mutations cause partial androgen insensitivity (PAI) with frank genital ambiguity that may engender appreciable parental anxiety and patient morbidity. If the AR mutation in a PAI family is unknown, the AR`s intragenic trinucleotide repeat polymorphisms may be used for prenatal diagnosis. However, intergenerational instability of repeat-size may be worrisome, particularly when the information alleles differ by only a few repeats. Here, we report the discovery of a codon-usage (silent substitution) variant inmore » the GGN repeat, and describe its use as a source of complementary information for prenatal diagnosis. The standard sense sequence of the (GGN){sub n} tract is (GGT){sub 3} GGG(GGT){sub 2} (GGC){sub 9-21}. On 4 of 27 X chromosomes we noted that the internal GGT sequence was expanded to 3 or 4 repeats. We used an internal (GGT){sub 4} repeat in a total (GGN){sub 24} tract together with a (CAG){sub 20} tract to distinguish an X chromosome with a mutant AR allele from another X chromosome, bearing a normal allele, that had an internal (GGT){sub 2} repeat in a total (GGN){sub 23} tract together with a (CAG){sub 21} tract. Subsequently, we found the base change leading to a pathogenic amino acid substitution (M779I) in codon 6 of the mutant AR gene in an affected maternal aunt and the fetus at risk. This confirmed the prenatal diagnosis based on the intragenic trinucleotide repeat polymorphisms, and it strengthened the prediction of external genital ambiguity using our previous experience with M779I in another family.« less

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 88. Part 5. (Cold Spring Construction Co.-Dat Construction, Inc.)

DTIC Science & Technology

1988-01-01

0 0 00 00 00 000 000 00 Zo@00- 01 4 4 0- 4 4c cc 44 4 04C - ICON IW W.) I.- - 1- 0 ~ 0C) O - CO o@00- 1o ZL 0 0ol 40 14- 00 00ifLA1 00 00 0 0 000-4 ZN...0-4In -4 300 co 341- 0) 40 A0n 1- 1MCIC 3 .j > > > > 4c .i > 00NVO 0I00W.3N III d4 U) (16 (A 0. 1L. 00.1*. .L. 4 ICON 1 1.- 00l.- 00000000 lK’IAC0N I...0000 340M 11� 100 a5 - 3444444 0 IZEZ 3 0 CON a(0((Il(NfN00-4 N tow0 O~4(.0 ~ 1(0 alocos00 < 0" I 00000004fl.4-N00 0(09- Mm01 momoul-NM-4U

Prime Contractors with Awards Over $25,000 by Name, Location, and Contract Number, Fiscal Year 87. Part 4. Drummey Rosane Anderson, Incorporated-Gabbert Broweleit Ptrsn., Incorported PS.

DTIC Science & Technology

1987-01-01

F5 - F-’ R.4 8,4 1%s Rb’ owv.*- ~ ~ v.w~ .91 ~ ~ - l ~f ~J C\\JCIF; W...0C,( I I I~.I.I. zzzzzzzz I 0 01 04 c8&.I c.4- 8- I -’N---I I 0%- - 0I 0-1- 14 >>I "N > I164 -I I u C - I L 2 * 0I U - I3 8 F5 I N mI L) I m 910 8 1...LX~~~a L I onW~ m 144 x.-t ZC um, ’ 1 9 I- wd. w W 4WW >wu cc Zu LI0 I o L i z -c - -’ L- F5 w C. * ~ % * #- ~ ~~’ C.𔃻 1 *< -tl z Cc4. .4 ’

Highly Efficient Performance and Conversion Pathway of Photocatalytic CH3SH Oxidation on Self-Stabilized Indirect Z-Scheme g-C3N4/I3--BiOI.

PubMed

Hu, Lingling; He, Huanjunwa; Xia, Dehua; Huang, Yajing; Xu, Jiarong; Li, Haoyue; He, Chun; Yang, Wenjing; Shu, Dong; Wong, Po Keung

2018-06-06

A self-stabilized Z-scheme porous g-C 3 N 4 /I 3- -containing BiOI ultrathin nanosheets (g-C 3 N 4 /I 3- -BiOI) heterojunction photocatalyst with I 3 - /I - redox mediator was successfully synthesized by a facile solvothermal method coupling with light illumination. The structure and optical properties of g-C 3 N 4 /I 3- -BiOI composites were systematically characterized by means of X-ray diffraction, scanning electron microscopy, transmission electron microscopy, Fourier transform infrared, X-ray photoelectron spectroscopy, N 2 adsorption/desorption, UV-vis diffuse reflectance spectrum, and photoluminescence. The g-C 3 N 4 /I 3- -BiOI composites, with a heterojunction between porous g-C 3 N 4 and BiOI ultrathin nanosheets, were first applied for the photocatalytic elimination of ppm-leveled CH 3 SH under light-emitting diode visible light illumination. The g-C 3 N 4 /I 3- -BiOI heterojunction with 10% g-C 3 N 4 showed a dramatically enhanced photocatalytic activity in the removal of CH 3 SH compared with pure BiOI and g-C 3 N 4 due to its effective interfacial charge transfer and separation. The adsorption and photocatalytic oxidation of CH 3 SH over g-C 3 N 4 /I 3- -BiOI were deeply explored by in situ diffuse reflectance infrared Fourier transform spectroscopy, and the intermediates and conversion pathways were elucidated and compared. Furthermore, on the basis of reactive species trapping, electron spin resonance and Mott-Schottky experiments, it was revealed that the responsible reactive species for catalytic CH 3 SH composition were h + , • O 2 - , and 1 O 2 ; thus, the g-C 3 N 4 /I 3- -BiOI heterojunction followed an indirect all-solid state Z-scheme charge-transfer mode with self-stabilized I 3 - /I - pairs as redox mediator, which could accelerate the separation of photogenerated charge and enhance the redox reaction power of charged carriers simultaneously.

Lake Ladora and Lake Mary Phase 2 Data Addendum Site 2-17 Task No. 20 - Lower Lakes Version 3.1.

DTIC Science & Technology

1988-10-01

4 E4 1>E 0 0 m 41 a l 0 0 1. 1-0 0. A 0a L I 0a c0 C4 LI C S .-4 ItI * M 1 0 0C41 C4 0 .4 .1 L E- .0 C 5 L I4 I10L d 0 0 0 000 0 ii 0 0 8 000 0d 0kI 4...L N L S 0L 4)4N L? 4C 0) 0C 0 P) 4?10-0 0 L E- n’ 4 0 O W L IL 0 0 3, 0 CJ -i J- tD >.nx i I 009H t98 )-)I- , 00 *I080000 *000- 00 888 0 00088 00000

Resistance and Stock Propulsion on the High Speed Sealift (HSS) Hybrid Contra-Rotating Shaft-Pod (HCRSP) Concept, Model 5653-3A

DTIC Science & Technology

2008-09-01

8217 I l ALW N- N OD0 OH (N IV’ W 00 H- -W’ 0) (Nq Ht DC1 C’w H HH HrHir-1r-1C4(N N m 0H 0 E rr.. .1 0 29H0UH WP 4t or -u HH H HN wo)w i o I CW0W M IDID01...l C4 H NA a) N’ N) ~ N C14 N m m U m (0 a) m H (N U M m v IV -IN . . . . . . $-Na A F- " (N -l(04" 04 -4 -4" Ht -4 F- e~N rlN m H 0 CmN’rCr m ) m mmm...H O H-4 LALANOLAHCO)a)C"la)iL. . .N.a. .OHA.. . H.N.N.O.N.l. . 0HH H H H kel( N O L A 0 M m.) L ( 0 1 WmmN r 1 4 4w o oW W 6m o ( o,WmL A6L A 6L A L

Suicidal ideation and suicide attempts in children and adolescents with bipolar disorder: a systematic review of prevalence and incidence rates, risk factors, and targeted interventions

PubMed Central

Hauser, Marta; Galling, Britta; Correll, Christoph U

2013-01-01

Objective Pediatric bipolar disorder (PBD) is associated with poor outcomes, including suicidal ideation (SI) and suicide attempt (SA). However, frequencies and risk factors of SI/SA and targeted intervention trials for SI/SA in PBD have not been reviewed systematically. Methods We conducted a systematic PubMed review, searching for articles reporting on prevalences/incidences, correlates and intervention studies targeting SI/SA in PBD. Weighted means were calculated, followed by an exploratory meta-regression of SI and SA correlates. Results Fourteen studies (n = 1,595) with 52.1% males aged 14.4 years reported data on SI/SA prevalence (N = 13, n = 1,508) and/or correlates (N = 10, n = 1,348) in PBD. Weighted mean prevalences were: past SI = 57.4%, past SA = 21.3%, current SI = 50.4%, and current SA = 25.5%; incidences (mean: 42 months follow-up were: SI = 14.6% and SA = 14.7%. Regarding significant correlates, SI (N = 3) was associated with a higher percentage of Caucasian race, narrow (as opposed to broad) PBD phenotype, younger age, and higher quality of life than SA. Significant correlates of SA (N = 10) included female gender, older age, earlier illness onset, more severe/episodic PBD, mixed episodes, comorbid disorders, past self-injurious behavior/SI/SA, physical/sexual abuse, parental depression, family history of suicidality, and poor family functioning. Race, socioeconomic status, living situation, and life events were not clearly associated with SA. In a meta-regression analysis, bipolar I disorder and comorbid attention-deficit hyperactivity disorder were significantly associated with SA. Only one open label study targeting the reduction of SI/SA in PBD was identified. Conclusions SI and SA are highly common but under-investigated in PBD. Exploration of predictors and protective factors is imperative for the establishment of effective preventive and intervention strategies, which are urgently needed. PMID:23829436

Bird Ingestion into Large Turbofan Engines

DTIC Science & Technology

1992-05-01

4 JKT JAKARTA, INDONESIA 1 KCZ KOCHI,JAPAN 4 4 KIJ NIGATA,JAPAN 1 1 MYJ MATSUYAMA,JAPAN 2 2 NGO NAGOYA,JAPAN 2 1. 3 NRT TOKYO-NRT, JAPA-N 1 1 2...BL OEUOIj N H 1 G TODENT tip riP N I N NC 6 N iaNOMMN P112CR (lJnlE ;?Pi 1 1.4 N I HC N V:11 V 2 10I PR FO REPLED, 12? COWL RISETS FRrIPTTR 16 Nq...PRRPFHlH( 014 N 1 Nl N CU.4L I l1$0 N 1m V 2’ 1 NYC. 515 F C’L:ý O1110.PREPLITE IlINP. ID? LII N Vt’ 1 1 1: 0 LE CURL 140. V44F.PRF11O’:6 IARLLN 114

Community Detection in Sparse Random Networks

DTIC Science & Technology

2013-08-13

if, (i, j) ∈ E , meaning there is an edge between nodes i, j ∈ V. Note that W is symmetric, and we assume that Wii = 0 for all i. Under the null... Wii = 0.) Our arguments are parallel to those we used under P0, the only difficulty being that Wi is not binomial anymore. Indeed, WSi ∼ Bin(n − 1, p1...Berlin: Springer. Alon, N. and S. Gutner (2010). Balanced families of perfect hash functions and their applications. ACM Trans. Algorithms 6 (3), Art

Architecture of an Integrated Microelectronic Warfare System-on-a-Chip and Design of Key Components

DTIC Science & Technology

2004-12-01

N -modulus case results in 0 1 2 3 4 ( ii i i i i i i m e s s s s s s 1)−= + + + +L , (5.55) for an even modulus, and 0 1 2 3 4 ( 2) (i ii i...2 2 3 2 2 1 1 0 1 , , , , . N N N N N N N MRSS e e MRSS e e MRSS e e MRSS e e MRSS e e − − 1− − − = ⊕ = ⊕ = ⊕ = ⊕ = ⊕ M (5.58) Like the