Simple Parametric Model for Airfoil Shape Description
NASA Astrophysics Data System (ADS)
Ziemkiewicz, David
2017-12-01
We show a simple, analytic equation describing a class of two-dimensional shapes well suited for representation of aircraft airfoil profiles. Our goal was to create a description characterized by a small number of parameters with easily understandable meaning, providing a tool to alter the shape with optimization procedures as well as manual tweaks by the designer. The generated shapes are well suited for numerical analysis with 2D flow solving software such as XFOIL.
An analytical treatment for three neutrino oscillations in the Earth
NASA Astrophysics Data System (ADS)
Aguilar-Arevalo, A. A.; D'Olivo, J. C.; Supanitsky, A. D.
2012-08-01
A simple, and at the same time accurate, description of the Earth matter effects on the oscillations between three neutrino flavors is given in terms of the Magnus expansion for the evolution operator.
On the theory of evolution of particulate systems
NASA Astrophysics Data System (ADS)
Buyevich, Yuri A.; Alexandrov, Dmitri V.
2017-04-01
An analytical method for the description of particulate systems at sufficiently long times is developed. This method allows us to obtain very simple analytical expressions for the particle distribution function. The method under consideration can be applied to a number of practically important problems including evaporation of a polydisperse mist, dissolution of dispersed solids, combustion of dispersed propellants, physical and chemical transformation of powders and phase transitions in metastable materials.
Oblique Impact Ejecta Flow Fields: An Application of Maxwells Z Model
NASA Technical Reports Server (NTRS)
Anderson, J. L. B.; Schultz, P. H.; Heineck, J. T.
2001-01-01
Oblique impact flow fields show an evolution from asymmetric to symmetric ejecta flow. This evolution can be put into the simple analytical description of the evolving flow field origin using the Maxwell Z Model. Additional information is contained in the original extended abstract.
On the use of Lagrangian variables in descriptions of unsteady boundary-layer separation
NASA Technical Reports Server (NTRS)
Cowley, Stephen J.; Vandommelen, Leon L.; Lam, Shui T.
1990-01-01
The Lagrangian description of unsteady boundary layer separation is reviewed from both analytical and numerical perspectives. It is explained in simple terms how particle distortion gives rise to unsteady separation, and why a theory centered on Lagrangian coordinates provides the clearest description of this phenomenon. Some of the more recent results for unsteady three dimensional compressible separation are included. The different forms of separation that can arise from symmetries are emphasized. A possible description of separation is also included when the detaching vorticity layer exits the classical boundary layer region, but still remains much closer to the surface than a typical body-lengthscale.
Analysis of Mathematical Modelling on Potentiometric Biosensors
Mehala, N.; Rajendran, L.
2014-01-01
A mathematical model of potentiometric enzyme electrodes for a nonsteady condition has been developed. The model is based on the system of two coupled nonlinear time-dependent reaction diffusion equations for Michaelis-Menten formalism that describes the concentrations of substrate and product within the enzymatic layer. Analytical expressions for the concentration of substrate and product and the corresponding flux response have been derived for all values of parameters using the new homotopy perturbation method. Furthermore, the complex inversion formula is employed in this work to solve the boundary value problem. The analytical solutions obtained allow a full description of the response curves for only two kinetic parameters (unsaturation/saturation parameter and reaction/diffusion parameter). Theoretical descriptions are given for the two limiting cases (zero and first order kinetics) and relatively simple approaches for general cases are presented. All the analytical results are compared with simulation results using Scilab/Matlab program. The numerical results agree with the appropriate theories. PMID:25969765
Analysis of mathematical modelling on potentiometric biosensors.
Mehala, N; Rajendran, L
2014-01-01
A mathematical model of potentiometric enzyme electrodes for a nonsteady condition has been developed. The model is based on the system of two coupled nonlinear time-dependent reaction diffusion equations for Michaelis-Menten formalism that describes the concentrations of substrate and product within the enzymatic layer. Analytical expressions for the concentration of substrate and product and the corresponding flux response have been derived for all values of parameters using the new homotopy perturbation method. Furthermore, the complex inversion formula is employed in this work to solve the boundary value problem. The analytical solutions obtained allow a full description of the response curves for only two kinetic parameters (unsaturation/saturation parameter and reaction/diffusion parameter). Theoretical descriptions are given for the two limiting cases (zero and first order kinetics) and relatively simple approaches for general cases are presented. All the analytical results are compared with simulation results using Scilab/Matlab program. The numerical results agree with the appropriate theories.
A simple analytical model for signal amplification by reversible exchange (SABRE) process.
Barskiy, Danila A; Pravdivtsev, Andrey N; Ivanov, Konstantin L; Kovtunov, Kirill V; Koptyug, Igor V
2016-01-07
We demonstrate an analytical model for the description of the signal amplification by reversible exchange (SABRE) process. The model relies on a combined analysis of chemical kinetics and the evolution of the nuclear spin system during the hyperpolarization process. The presented model for the first time provides rationale for deciding which system parameters (i.e. J-couplings, relaxation rates, reaction rate constants) have to be optimized in order to achieve higher signal enhancement for a substrate of interest in SABRE experiments.
Automation effects in a multiloop manual control system
NASA Technical Reports Server (NTRS)
Hess, R. A.; Mcnally, B. D.
1986-01-01
An experimental and analytical study was undertaken to investigate human interaction with a simple multiloop manual control system in which the human's activity was systematically varied by changing the level of automation. The system simulated was the longitudinal dynamics of a hovering helicopter. The automation-systems-stabilized vehicle responses from attitude to velocity to position and also provided for display automation in the form of a flight director. The control-loop structure resulting from the task definition can be considered a simple stereotype of a hierarchical control system. The experimental study was complemented by an analytical modeling effort which utilized simple crossover models of the human operator. It was shown that such models can be extended to the description of multiloop tasks involving preview and precognitive human operator behavior. The existence of time optimal manual control behavior was established for these tasks and the role which internal models may play in establishing human-machine performance was discussed.
Modern analytical chemistry in the contemporary world
NASA Astrophysics Data System (ADS)
Šíma, Jan
2016-12-01
Students not familiar with chemistry tend to misinterpret analytical chemistry as some kind of the sorcery where analytical chemists working as modern wizards handle magical black boxes able to provide fascinating results. However, this approach is evidently improper and misleading. Therefore, the position of modern analytical chemistry among sciences and in the contemporary world is discussed. Its interdisciplinary character and the necessity of the collaboration between analytical chemists and other experts in order to effectively solve the actual problems of the human society and the environment are emphasized. The importance of the analytical method validation in order to obtain the accurate and precise results is highlighted. The invalid results are not only useless; they can often be even fatal (e.g., in clinical laboratories). The curriculum of analytical chemistry at schools and universities is discussed. It is referred to be much broader than traditional equilibrium chemistry coupled with a simple description of individual analytical methods. Actually, the schooling of analytical chemistry should closely connect theory and practice.
An accurate analytic description of neutrino oscillations in matter
NASA Astrophysics Data System (ADS)
Akhmedov, E. Kh.; Niro, Viviana
2008-12-01
A simple closed-form analytic expression for the probability of two-flavour neutrino oscillations in a matter with an arbitrary density profile is derived. Our formula is based on a perturbative expansion and allows an easy calculation of higher order corrections. The expansion parameter is small when the density changes relatively slowly along the neutrino path and/or neutrino energy is not very close to the Mikheyev-Smirnov-Wolfenstein (MSW) resonance energy. Our approximation is not equivalent to the adiabatic approximation and actually goes beyond it. We demonstrate the validity of our results using a few model density profiles, including the PREM density profile of the Earth. It is shown that by combining the results obtained from the expansions valid below and above the MSW resonance one can obtain a very good description of neutrino oscillations in matter in the entire energy range, including the resonance region.
NASA Astrophysics Data System (ADS)
Gagatsos, Christos N.; Karanikas, Alexandros I.; Kordas, Georgios; Cerf, Nicolas J.
2016-02-01
In spite of their simple description in terms of rotations or symplectic transformations in phase space, quadratic Hamiltonians such as those modelling the most common Gaussian operations on bosonic modes remain poorly understood in terms of entropy production. For instance, determining the quantum entropy generated by a Bogoliubov transformation is notably a hard problem, with generally no known analytical solution, while it is vital to the characterisation of quantum communication via bosonic channels. Here we overcome this difficulty by adapting the replica method, a tool borrowed from statistical physics and quantum field theory. We exhibit a first application of this method to continuous-variable quantum information theory, where it enables accessing entropies in an optical parametric amplifier. As an illustration, we determine the entropy generated by amplifying a binary superposition of the vacuum and a Fock state, which yields a surprisingly simple, yet unknown analytical expression.
Phenomenology of wall-bounded Newtonian turbulence.
L'vov, Victor S; Pomyalov, Anna; Procaccia, Itamar; Zilitinkevich, Sergej S
2006-01-01
We construct a simple analytic model for wall-bounded turbulence, containing only four adjustable parameters. Two of these parameters are responsible for the viscous dissipation of the components of the Reynolds stress tensor. The other two parameters control the nonlinear relaxation of these objects. The model offers an analytic description of the profiles of the mean velocity and the correlation functions of velocity fluctuations in the entire boundary region, from the viscous sublayer, through the buffer layer, and further into the log-law turbulent region. In particular, the model predicts a very simple distribution of the turbulent kinetic energy in the log-law region between the velocity components: the streamwise component contains a half of the total energy whereas the wall-normal and cross-stream components contain a quarter each. In addition, the model predicts a very simple relation between the von Kármán slope k and the turbulent velocity in the log-law region v+ (in wall units): v+=6k. These predictions are in excellent agreement with direct numerical simulation data and with recent laboratory experiments.
NASA Astrophysics Data System (ADS)
Dutta, Ivy; Chowdhury, Anirban Roy; Kumbhakar, Dharmadas
2013-03-01
Using Chebyshev power series approach, accurate description for the first higher order (LP11) mode of graded index fibers having three different profile shape functions are presented in this paper and applied to predict their propagation characteristics. These characteristics include fractional power guided through the core, excitation efficiency and Petermann I and II spot sizes with their approximate analytic formulations. We have shown that where two and three Chebyshev points in LP11 mode approximation present fairly accurate results, the values based on our calculations involving four Chebyshev points match excellently with available exact numerical results.
Analytic descriptions of cylindrical electromagnetic waves in a nonlinear medium
Xiong, Hao; Si, Liu-Gang; Yang, Xiaoxue; Wu, Ying
2015-01-01
A simple but highly efficient approach for dealing with the problem of cylindrical electromagnetic waves propagation in a nonlinear medium is proposed based on an exact solution proposed recently. We derive an analytical explicit formula, which exhibiting rich interesting nonlinear effects, to describe the propagation of any amount of cylindrical electromagnetic waves in a nonlinear medium. The results obtained by using the present method are accurately concordant with the results of using traditional coupled-wave equations. As an example of application, we discuss how a third wave affects the sum- and difference-frequency generation of two waves propagation in the nonlinear medium. PMID:26073066
Nursing education: contradictions and challenges of pedagogical practice.
Pinto, Joelma Batista Tebaldi; Pepe, Alda Muniz
2007-01-01
This study deals with the nursing curriculum, pedagogical practice and education. Nowadays, this theme has taken up considerable space in academic debates. Thus, this study aimed to get empirical knowledge and provide an analytical description of the academic reality of nursing education at Santa Cruz State University in the undergraduate nursing course. This is a descriptive study, which may provide a new view of the problem, with careful observation, description, and exploration of the situation aspects, interpreting the reality, without interfering in it and, consequently, being open to new studies. Descriptive statistics with simple frequency and percentage calculation was applied. In summary, results indicate that professors and students have difficulties to evaluate the curriculum. In addition, the curriculum under study is characterized as a collection curriculum, with a pedagogical practice predominantly directed at the traditional model. Hence, nursing education still shows features of the biomedical-technical model.
Brief communication: Skeletal biology past and present: Are we moving in the right direction?
Hens, Samantha M; Godde, Kanya
2008-10-01
In 1982, Spencer's edited volume A History of American Physical Anthropology: 1930-1980 allowed numerous authors to document the state of our science, including a critical examination of skeletal biology. Some authors argued that the first 50 years of skeletal biology were characterized by the descriptive-historical approach with little regard for processual problems and that technological and statistical analyses were not rooted in theory. In an effort to determine whether Spencer's landmark volume impacted the field of skeletal biology, a content analysis was carried out for the American Journal of Physical Anthropology from 1980 to 2004. The percentage of skeletal biology articles is similar to that of previous decades. Analytical articles averaged only 32% and are defined by three criteria: statistical analysis, hypothesis testing, and broader explanatory context. However, when these criteria were scored individually, nearly 80% of papers attempted a broader theoretical explanation, 44% tested hypotheses, and 67% used advanced statistics, suggesting that the skeletal biology papers in the journal have an analytical emphasis. Considerable fluctuation exists between subfields; trends toward a more analytical approach are witnessed in the subfields of age/sex/stature/demography, skeletal maturation, anatomy, and nonhuman primate studies, which also increased in frequency, while paleontology and pathology were largely descriptive. Comparisons to the International Journal of Osteoarchaeology indicate that there are statistically significant differences between the two journals in terms of analytical criteria. These data indicate a positive shift in theoretical thinking, i.e., an attempt by most to explain processes rather than present a simple description of events.
Fast Quantum Algorithm for Predicting Descriptive Statistics of Stochastic Processes
NASA Technical Reports Server (NTRS)
Williams Colin P.
1999-01-01
Stochastic processes are used as a modeling tool in several sub-fields of physics, biology, and finance. Analytic understanding of the long term behavior of such processes is only tractable for very simple types of stochastic processes such as Markovian processes. However, in real world applications more complex stochastic processes often arise. In physics, the complicating factor might be nonlinearities; in biology it might be memory effects; and in finance is might be the non-random intentional behavior of participants in a market. In the absence of analytic insight, one is forced to understand these more complex stochastic processes via numerical simulation techniques. In this paper we present a quantum algorithm for performing such simulations. In particular, we show how a quantum algorithm can predict arbitrary descriptive statistics (moments) of N-step stochastic processes in just O(square root of N) time. That is, the quantum complexity is the square root of the classical complexity for performing such simulations. This is a significant speedup in comparison to the current state of the art.
Cavity Optical Pulse Extraction: ultra-short pulse generation as seeded Hawking radiation.
Eilenberger, Falk; Kabakova, Irina V; de Sterke, C Martijn; Eggleton, Benjamin J; Pertsch, Thomas
2013-01-01
We show that light trapped in an optical cavity can be extracted from that cavity in an ultrashort burst by means of a trigger pulse. We find a simple analytic description of this process and show that while the extracted pulse inherits its pulse length from that of the trigger pulse, its wavelength can be completely different. Cavity Optical Pulse Extraction is thus well suited for the development of ultrashort laser sources in new wavelength ranges. We discuss similarities between this process and the generation of Hawking radiation at the optical analogue of an event horizon with extremely high Hawking temperature. Our analytic predictions are confirmed by thorough numerical simulations.
Cavity Optical Pulse Extraction: ultra-short pulse generation as seeded Hawking radiation
Eilenberger, Falk; Kabakova, Irina V.; de Sterke, C. Martijn; Eggleton, Benjamin J.; Pertsch, Thomas
2013-01-01
We show that light trapped in an optical cavity can be extracted from that cavity in an ultrashort burst by means of a trigger pulse. We find a simple analytic description of this process and show that while the extracted pulse inherits its pulse length from that of the trigger pulse, its wavelength can be completely different. Cavity Optical Pulse Extraction is thus well suited for the development of ultrashort laser sources in new wavelength ranges. We discuss similarities between this process and the generation of Hawking radiation at the optical analogue of an event horizon with extremely high Hawking temperature. Our analytic predictions are confirmed by thorough numerical simulations. PMID:24060831
Contact Kinetics in Fractal Macromolecules.
Dolgushev, Maxim; Guérin, Thomas; Blumen, Alexander; Bénichou, Olivier; Voituriez, Raphaël
2015-11-13
We consider the kinetics of first contact between two monomers of the same macromolecule. Relying on a fractal description of the macromolecule, we develop an analytical method to compute the mean first contact time for various molecular sizes. In our theoretical description, the non-Markovian feature of monomer motion, arising from the interactions with the other monomers, is captured by accounting for the nonequilibrium conformations of the macromolecule at the very instant of first contact. This analysis reveals a simple scaling relation for the mean first contact time between two monomers, which involves only their equilibrium distance and the spectral dimension of the macromolecule, independently of its microscopic details. Our theoretical predictions are in excellent agreement with numerical stochastic simulations.
Locomotion of C. elegans: A Piecewise-Harmonic Curvature Representation of Nematode Behavior
Padmanabhan, Venkat; Khan, Zeina S.; Solomon, Deepak E.; Armstrong, Andrew; Rumbaugh, Kendra P.; Vanapalli, Siva A.; Blawzdziewicz, Jerzy
2012-01-01
Caenorhabditis elegans, a free-living soil nematode, displays a rich variety of body shapes and trajectories during its undulatory locomotion in complex environments. Here we show that the individual body postures and entire trails of C. elegans have a simple analytical description in curvature representation. Our model is based on the assumption that the curvature wave is generated in the head segment of the worm body and propagates backwards. We have found that a simple harmonic function for the curvature can capture multiple worm shapes during the undulatory movement. The worm body trajectories can be well represented in terms of piecewise sinusoidal curvature with abrupt changes in amplitude, wavevector, and phase. PMID:22792224
New hybrid voxelized/analytical primitive in Monte Carlo simulations for medical applications
NASA Astrophysics Data System (ADS)
Bert, Julien; Lemaréchal, Yannick; Visvikis, Dimitris
2016-05-01
Monte Carlo simulations (MCS) applied in particle physics play a key role in medical imaging and particle therapy. In such simulations, particles are transported through voxelized phantoms derived from predominantly patient CT images. However, such voxelized object representation limits the incorporation of fine elements, such as artificial implants from CAD modeling or anatomical and functional details extracted from other imaging modalities. In this work we propose a new hYbrid Voxelized/ANalytical primitive (YVAN) that combines both voxelized and analytical object descriptions within the same MCS, without the need to simultaneously run two parallel simulations, which is the current gold standard methodology. Given that YVAN is simply a new primitive object, it does not require any modifications on the underlying MC navigation code. The new proposed primitive was assessed through a first simple MCS. Results from the YVAN primitive were compared against an MCS using a pure analytical geometry and the layer mass geometry concept. A perfect agreement was found between these simulations, leading to the conclusion that the new hybrid primitive is able to accurately and efficiently handle phantoms defined by a mixture of voxelized and analytical objects. In addition, two application-based evaluation studies in coronary angiography and intra-operative radiotherapy showed that the use of YVAN was 6.5% and 12.2% faster than the layered mass geometry method, respectively, without any associated loss of accuracy. However, the simplification advantages and differences in computational time improvements obtained with YVAN depend on the relative proportion of the analytical and voxelized structures used in the simulation as well as the size and number of triangles used in the description of the analytical object meshes.
I'll take that to go: Big data bags and minimal identifiers for exchange of large, complex datasets
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chard, Kyle; D'Arcy, Mike; Heavner, Benjamin D.
Big data workflows often require the assembly and exchange of complex, multi-element datasets. For example, in biomedical applications, the input to an analytic pipeline can be a dataset consisting thousands of images and genome sequences assembled from diverse repositories, requiring a description of the contents of the dataset in a concise and unambiguous form. Typical approaches to creating datasets for big data workflows assume that all data reside in a single location, requiring costly data marshaling and permitting errors of omission and commission because dataset members are not explicitly specified. We address these issues by proposing simple methods and toolsmore » for assembling, sharing, and analyzing large and complex datasets that scientists can easily integrate into their daily workflows. These tools combine a simple and robust method for describing data collections (BDBags), data descriptions (Research Objects), and simple persistent identifiers (Minids) to create a powerful ecosystem of tools and services for big data analysis and sharing. We present these tools and use biomedical case studies to illustrate their use for the rapid assembly, sharing, and analysis of large datasets.« less
A simple model for strong ground motions and response spectra
Safak, Erdal; Mueller, Charles; Boatwright, John
1988-01-01
A simple model for the description of strong ground motions is introduced. The model shows that response spectra can be estimated by using only four parameters of the ground motion, the RMS acceleration, effective duration and two corner frequencies that characterize the effective frequency band of the motion. The model is windowed band-limited white noise, and is developed by studying the properties of two functions, cumulative squared acceleration in the time domain, and cumulative squared amplitude spectrum in the frequency domain. Applying the methods of random vibration theory, the model leads to a simple analytical expression for the response spectra. The accuracy of the model is checked by using the ground motion recordings from the aftershock sequences of two different earthquakes and simulated accelerograms. The results show that the model gives a satisfactory estimate of the response spectra.
Lloyd, Jeffrey T.; Clayton, John D.; Austin, Ryan A.; ...
2015-07-10
Background: The shock response of metallic single crystals can be captured using a micro-mechanical description of the thermoelastic-viscoplastic material response; however, using a such a description within the context of traditional numerical methods may introduce a physical artifacts. Advantages and disadvantages of complex material descriptions, in particular the viscoplastic response, must be framed within approximations introduced by numerical methods. Methods: Three methods of modeling the shock response of metallic single crystals are summarized: finite difference simulations, steady wave simulations, and algebraic solutions of the Rankine-Hugoniot jump conditions. For the former two numerical techniques, a dislocation density based framework describes themore » rate- and temperature-dependent shear strength on each slip system. For the latter analytical technique, a simple (two-parameter) rate- and temperature-independent linear hardening description is necessarily invoked to enable simultaneous solution of the governing equations. For all models, the same nonlinear thermoelastic energy potential incorporating elastic constants of up to order 3 is applied. Results: Solutions are compared for plate impact of highly symmetric orientations (all three methods) and low symmetry orientations (numerical methods only) of aluminum single crystals shocked to 5 GPa (weak shock regime) and 25 GPa (overdriven regime). Conclusions: For weak shocks, results of the two numerical methods are very similar, regardless of crystallographic orientation. For strong shocks, artificial viscosity affects the finite difference solution, and effects of transverse waves for the lower symmetry orientations not captured by the steady wave method become important. The analytical solution, which can only be applied to highly symmetric orientations, provides reasonable accuracy with regards to prediction of most variables in the final shocked state but, by construction, does not provide insight into the shock structure afforded by the numerical methods.« less
Variational description of the positive column with two-stem ionization
NASA Technical Reports Server (NTRS)
Crawford, F. W.
1979-01-01
The ionization balance in diffusion dominated discharges which depends on both one and two step ionization processes is considered. The Spenke diffusion equation (D sq delta n + neutrino n + sq kn =0) describing such conditions is solved by the Rayleigh-Ritz variational method. Simple analytic approximations to the density profile, and the similarity relation between neutrino,k,D and the discharge dimensions, are derived for planar and cylindrical geometry, and compared with exact computations for certain limiting cases.
NASA Astrophysics Data System (ADS)
Robotham, A. S. G.; Howlett, Cullan
2018-06-01
In this short note we publish the analytic quantile function for the Navarro, Frenk & White (NFW) profile. All known published and coded methods for sampling from the 3D NFW PDF use either accept-reject, or numeric interpolation (sometimes via a lookup table) for projecting random Uniform samples through the quantile distribution function to produce samples of the radius. This is a common requirement in N-body initial condition (IC), halo occupation distribution (HOD), and semi-analytic modelling (SAM) work for correctly assigning particles or galaxies to positions given an assumed concentration for the NFW profile. Using this analytic description allows for much faster and cleaner code to solve a common numeric problem in modern astronomy. We release R and Python versions of simple code that achieves this sampling, which we note is trivial to reproduce in any modern programming language.
Fall Velocities of Hydrometeors in the Atmosphere: Refinements to a Continuous Analytical Power Law.
NASA Astrophysics Data System (ADS)
Khvorostyanov, Vitaly I.; Curry, Judith A.
2005-12-01
This paper extends the previous research of the authors on the unified representation of fall velocities for both liquid and crystalline particles as a power law over the entire size range of hydrometeors observed in the atmosphere. The power-law coefficients are determined as continuous analytical functions of the Best or Reynolds number or of the particle size. Here, analytical expressions are formulated for the turbulent corrections to the Reynolds number and to the power-law coefficients that describe the continuous transition from the laminar to the turbulent flow around a falling particle. A simple analytical expression is found for the correction of fall velocities for temperature and pressure. These expressions and the resulting fall velocities are compared with observations and other calculations for a range of ice crystal habits and sizes. This approach provides a continuous analytical power-law description of the terminal velocities of liquid and crystalline hydrometeors with sufficiently high accuracy and can be directly used in bin-resolving models or incorporated into parameterizations for cloud- and large-scale models and remote sensing techniques.
Active Tailoring of Lift Distribution to Enhance Cruise Performance
NASA Technical Reports Server (NTRS)
Flamm, Jeffrey D. (Technical Monitor); Pfeiffer, Neal J.; Christians, Joel G.
2005-01-01
During Phase I of this project, Raytheon Aircraft Company (RAC) has analytically and experimentally evaluated key components of a system that could be implemented for active tailoring of wing lift distribution using low-drag, trailing-edge modifications. Simple systems such as those studied by RAC could be used to enhance the cruise performance of a business jet configuration over a range of typical flight conditions. The trailing-edge modifications focus on simple, deployable mechanisms comprised of extendable small flap panels over portions of the span that could be used to subtly but positively optimize the lift and drag characteristics. The report includes results from low speed wind tunnel testing of the trailing-edge devices, descriptions of potential mechanisms for automation, and an assessment of the technology.
DNA DAMAGE QUANTITATION BY ALKALINE GEL ELECTROPHORESIS.
DOE Office of Scientific and Technical Information (OSTI.GOV)
SUTHERLAND,B.M.; BENNETT,P.V.; SUTHERLAND, J.C.
2004-03-24
Physical and chemical agents in the environment, those used in clinical applications, or encountered during recreational exposures to sunlight, induce damages in DNA. Understanding the biological impact of these agents requires quantitation of the levels of such damages in laboratory test systems as well as in field or clinical samples. Alkaline gel electrophoresis provides a sensitive (down to {approx} a few lesions/5Mb), rapid method of direct quantitation of a wide variety of DNA damages in nanogram quantities of non-radioactive DNAs from laboratory, field, or clinical specimens, including higher plants and animals. This method stems from velocity sedimentation studies of DNAmore » populations, and from the simple methods of agarose gel electrophoresis. Our laboratories have developed quantitative agarose gel methods, analytical descriptions of DNA migration during electrophoresis on agarose gels (1-6), and electronic imaging for accurate determinations of DNA mass (7-9). Although all these components improve sensitivity and throughput of large numbers of samples (7,8,10), a simple version using only standard molecular biology equipment allows routine analysis of DNA damages at moderate frequencies. We present here a description of the methods, as well as a brief description of the underlying principles, required for a simplified approach to quantitation of DNA damages by alkaline gel electrophoresis.« less
s -wave scattering length of a Gaussian potential
NASA Astrophysics Data System (ADS)
Jeszenszki, Peter; Cherny, Alexander Yu.; Brand, Joachim
2018-04-01
We provide accurate expressions for the s -wave scattering length for a Gaussian potential well in one, two, and three spatial dimensions. The Gaussian potential is widely used as a pseudopotential in the theoretical description of ultracold-atomic gases, where the s -wave scattering length is a physically relevant parameter. We first describe a numerical procedure to compute the value of the s -wave scattering length from the parameters of the Gaussian, but find that its accuracy is limited in the vicinity of singularities that result from the formation of new bound states. We then derive simple analytical expressions that capture the correct asymptotic behavior of the s -wave scattering length near the bound states. Expressions that are increasingly accurate in wide parameter regimes are found by a hierarchy of approximations that capture an increasing number of bound states. The small number of numerical coefficients that enter these expressions is determined from accurate numerical calculations. The approximate formulas combine the advantages of the numerical and approximate expressions, yielding an accurate and simple description from the weakly to the strongly interacting limit.
Polymers at interfaces and in colloidal dispersions.
Fleer, Gerard J
2010-09-15
This review is an extended version of the Overbeek lecture 2009, given at the occasion of the 23rd Conference of ECIS (European Colloid and Interface Society) in Antalya, where I received the fifth Overbeek Gold Medal awarded by ECIS. I first summarize the basics of numerical SF-SCF: the Scheutjens-Fleer version of Self-Consistent-Field theory for inhomogeneous systems, including polymer adsorption and depletion. The conformational statistics are taken from the (non-SCF) DiMarzio-Rubin lattice model for homopolymer adsorption, which enumerates the conformational details exactly by a discrete propagator for the endpoint distribution but does not account for polymer-solvent interaction and for the volume-filling constraint. SF-SCF corrects for this by adjusting the field such that it becomes self-consistent. The model can be generalized to more complex systems: polydispersity, brushes, random and block copolymers, polyelectrolytes, branching, surfactants, micelles, membranes, vesicles, wetting, etc. On a mean-field level the results are exact; the disadvantage is that only numerical data are obtained. Extensions to excluded-volume polymers are in progress. Analytical approximations for simple systems are based upon solving the Edwards diffusion equation. This equation is the continuum variant of the lattice propagator, but ignores the finite segment size (analogous to the Poisson-Boltzmann equation without a Stern layer). By using the discrete propagator for segments next to the surface as the boundary condition in the continuum model, the finite segment size can be introduced into the continuum description, like the ion size in the Stern-Poisson-Boltzmann model. In most cases a ground-state approximation is needed to find analytical solutions. In this way realistic analytical approximations for simple cases can be found, including depletion effects that occur in mixtures of colloids plus non-adsorbing polymers. In the final part of this review I discuss a generalization of the free-volume theory (FVT) for the phase behavior of colloids and non-adsorbing polymer. In FVT the polymer is considered to be ideal: the osmotic pressure Pi follows the Van 't Hoff law, the depletion thickness delta equals the radius of gyration. This restricts the validity of FVT to the so-called colloid limit (polymer much smaller than the colloids). We have been able to find simple analytical approximations for Pi and delta which account for non-ideality and include established results for the semidilute limit. So we could generalize FVT to GFVT, and can now also describe the so-called protein limit (polymer larger than the 'protein-like' colloids), where the binodal polymer concentrations scale in a simple way with the polymer/colloid size ratio. For an intermediate case (polymer size approximately colloid size) we could give a quantitative description of careful experimental data. Copyright 2010 Elsevier B.V. All rights reserved.
Geometerial description for a proposed aeroassist flight experiment vehicle
NASA Technical Reports Server (NTRS)
Cheatwood, F. M.; Dejarnette, F. J.; Hamilton, H. H., II
1986-01-01
One geometry currently under consideration for the Aeroassist Flight Experiment (AFE) vehicle is composed of several segments of simple general conics: an ellipsoidal nose tangent to an elliptical cone and a base skirt with the base plane raked relative to the body axis. An analytic representation for the body coordinates and first and second partial derivatives of this configuration has been developed. Equations are given which define the body radius and partial derivatives for a prescribed axial and circumferential position on the vehicle. The results for a sample case are tabulated and presented graphically.
Preparing Earth Data Scientists for 'The Sexiest Job of the 21st Century'
NASA Technical Reports Server (NTRS)
Kempler, Steven
2014-01-01
What Exactly do Earth Data Scientists do, and What do They Need to Know, to do It? There is not one simple answer, but there are many complex answers. Data Science, and data analytics, are new and nebulas, and takes on different characteristics depending on: The subject matter being analyzed, the maturity of the research, and whether the employed subject specific analytics is descriptive, diagnostic, discoveritive, predictive, or prescriptive, in nature. In addition, in a, thus far, business driven paradigm shift, university curriculums teaching data analytics pertaining to Earth science have, as a whole, lagged behind, andor have varied in approach.This presentation attempts to breakdown and identify the many activities that Earth Data Scientists, as a profession, encounter, as well as provide case studies of specific Earth Data Scientist and data analytics efforts. I will also address the educational preparation, that best equips future Earth Data Scientists, needed to further Earth science heterogeneous data research and applications analysis. The goal of this presentation is to describe the actual need for Earth Data Scientists and the practical skills to perform Earth science data analytics, thus hoping to initiate discussion addressing a baseline set of needed expertise for educating future Earth Data Scientists.
NASA Technical Reports Server (NTRS)
Migneault, G. E.
1979-01-01
Emulation techniques are proposed as a solution to a difficulty arising in the analysis of the reliability of highly reliable computer systems for future commercial aircraft. The difficulty, viz., the lack of credible precision in reliability estimates obtained by analytical modeling techniques are established. The difficulty is shown to be an unavoidable consequence of: (1) a high reliability requirement so demanding as to make system evaluation by use testing infeasible, (2) a complex system design technique, fault tolerance, (3) system reliability dominated by errors due to flaws in the system definition, and (4) elaborate analytical modeling techniques whose precision outputs are quite sensitive to errors of approximation in their input data. The technique of emulation is described, indicating how its input is a simple description of the logical structure of a system and its output is the consequent behavior. The use of emulation techniques is discussed for pseudo-testing systems to evaluate bounds on the parameter values needed for the analytical techniques.
Manipulation of the polarization of intense laser beams via optical wave mixing in plasmas
NASA Astrophysics Data System (ADS)
Michel, Pierre; Divol, Laurent; Turnbull, David; Moody, John
2014-10-01
When intense laser beams overlap in plasmas, the refractive index modulation created by the beat wave via the ponderomotive force can lead to optical wave mixing phenomena reminiscent of those used in crystals and photorefractive materials. Using a vector analysis, we present a full analytical description of the modification of the polarization state of laser beams crossing at arbitrary angles in a plasma. We show that plasmas can be used to provide full control of the polarization state of a laser beam, and give simple analytical estimates and practical considerations for the design of novel photonics devices such as plasma polarizers and plasma waveplates. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract No. DE-AC52-07NA27344.
Perez, Liliana I; Echarri, Rodolfo M; Garea, María T; Santiago, Guillermo D
2011-03-01
This work shows that all first- and second-order nongeometric effects on propagation, total or partial reflection, and transmission can be understood and evaluated considering the superposition of two plane waves. It also shows that this description yields results that are qualitatively and quantitatively compatible with those obtained by Fourier analysis of beams with Gaussian intensity distribution in any type of interface. In order to show this equivalence, we start by describing the first- and second-order nongeometric effects, and we calculate them analytically by superposing two plane waves. Finally, these results are compared with those obtained for the nongeometric effects of Gaussian beams in isotropic interfaces and are applied to different types of interfaces. A simple analytical expression for the angular shift is obtained considering the transmission of an extraordinary beam in a uniaxial-isotropic interface.
Morales, Daniel R.; Pacurariu, Alexandra; Kurz, Xavier
2017-01-01
Aims Evaluating the public health impact of regulatory interventions is important but there is currently no common methodological approach to guide this evaluation. This systematic review provides a descriptive overview of the analytical methods for impact research. Methods We searched MEDLINE and EMBASE for articles with an empirical analysis evaluating the impact of European Union or non‐European Union regulatory actions to safeguard public health published until March 2017. References from systematic reviews and articles from other known sources were added. Regulatory interventions, data sources, outcomes of interest, methodology and key findings were extracted. Results From 1246 screened articles, 229 were eligible for full‐text review and 153 articles in English language were included in the descriptive analysis. Over a third of articles studied analgesics and antidepressants. Interventions most frequently evaluated are regulatory safety communications (28.8%), black box warnings (23.5%) and direct healthcare professional communications (10.5%); 55% of studies measured changes in drug utilization patterns, 27% evaluated health outcomes, and 18% targeted knowledge, behaviour or changes in clinical practice. Unintended consequences like switching therapies or spill‐over effects were rarely evaluated. Two‐thirds used before–after time series and 15.7% before–after cross‐sectional study designs. Various analytical approaches were applied including interrupted time series regression (31.4%), simple descriptive analysis (28.8%) and descriptive analysis with significance tests (23.5%). Conclusion Whilst impact evaluation of pharmacovigilance and product‐specific regulatory interventions is increasing, the marked heterogeneity in study conduct and reporting highlights the need for scientific guidance to ensure robust methodologies are applied and systematic dissemination of results occurs. PMID:29105853
Universality of Generalized Parton Distributions in Light-Front Holographic QCD
NASA Astrophysics Data System (ADS)
de Téramond, Guy F.; Liu, Tianbo; Sufian, Raza Sabbir; Dosch, Hans Günter; Brodsky, Stanley J.; Deur, Alexandre; Hlfhs Collaboration
2018-05-01
The structure of generalized parton distributions is determined from light-front holographic QCD up to a universal reparametrization function w (x ) which incorporates Regge behavior at small x and inclusive counting rules at x →1 . A simple ansatz for w (x ) that fulfills these physics constraints with a single-parameter results in precise descriptions of both the nucleon and the pion quark distribution functions in comparison with global fits. The analytic structure of the amplitudes leads to a connection with the Veneziano model and hence to a nontrivial connection with Regge theory and the hadron spectrum.
Universality of Generalized Parton Distributions in Light-Front Holographic QCD.
de Téramond, Guy F; Liu, Tianbo; Sufian, Raza Sabbir; Dosch, Hans Günter; Brodsky, Stanley J; Deur, Alexandre
2018-05-04
The structure of generalized parton distributions is determined from light-front holographic QCD up to a universal reparametrization function w(x) which incorporates Regge behavior at small x and inclusive counting rules at x→1. A simple ansatz for w(x) that fulfills these physics constraints with a single-parameter results in precise descriptions of both the nucleon and the pion quark distribution functions in comparison with global fits. The analytic structure of the amplitudes leads to a connection with the Veneziano model and hence to a nontrivial connection with Regge theory and the hadron spectrum.
Semi-analytical model for a slab one-dimensional photonic crystal
NASA Astrophysics Data System (ADS)
Libman, M.; Kondratyev, N. M.; Gorodetsky, M. L.
2018-02-01
In our work we justify the applicability of a dielectric mirror model to the description of a real photonic crystal. We demonstrate that a simple one-dimensional model of a multilayer mirror can be employed for modeling of a slab waveguide with periodically changing width. It is shown that this width change can be recalculated to the effective refraction index modulation. The applicability of transfer matrix method of reflection properties calculation was demonstrated. Finally, our 1-D model was employed to analyze reflection properties of a 2-D structure - a slab photonic crystal with a number of elliptic holes.
Direct Numerical Simulations of Multiphase Flows
NASA Astrophysics Data System (ADS)
Tryggvason, Gretar
2013-03-01
Many natural and industrial processes, such as rain and gas exchange between the atmosphere and oceans, boiling heat transfer, atomization and chemical reactions in bubble columns, involve multiphase flows. Often the mixture can be described as a disperse flow where one phase consists of bubbles or drops. Direct numerical simulations (DNS) of disperse flow have recently been used to study the dynamics of multiphase flows with a large number of bubbles and drops, often showing that the collective motion results in relatively simple large-scale structure. Here we review simulations of bubbly flows in vertical channels where the flow direction, as well as the bubble deformability, has profound implications on the flow structure and the total flow rate. Results obtained so far are summarized and open questions identified. The resolution for DNS of multiphase flows is usually determined by a dominant scale, such as the average bubble or drop size, but in many cases much smaller scales are also present. These scales often consist of thin films, threads, or tiny drops appearing during coalescence or breakup, or are due to the presence of additional physical processes that operate on a very different time scale than the fluid flow. The presence of these small-scale features demand excessive resolution for conventional numerical approaches. However, at small flow scales the effects of surface tension are generally strong so the interface geometry is simple and viscous forces dominate the flow and keep it simple also. These are exactly the conditions under which analytical models can be used and we will discuss efforts to combine a semi-analytical description for the small-scale processes with a fully resolved simulation of the rest of the flow. We will, in particular, present an embedded analytical description to capture the mass transfer from bubbles in liquids where the diffusion of mass is much slower than the diffusion of momentum. This results in very thin mass-boundary layers that are difficult to resolve, but the new approach allows us to simulate the mass transfer from many freely evolving bubbles and examine the effect of the interactions of the bubbles with each other and the flow. We will conclude by attempting to summarize the current status of DNS of multiphase flows. Support by NSF and DOE (CASL)
Preparing Earth Data Scientists for 'the sexiest job of the 21st century'
NASA Astrophysics Data System (ADS)
Kempler, S. J.
2014-12-01
What Exactly do Earth Data Scientists do, and What do They Need to Know, to do It? There is not one simple answer, but there are many complex answers. Data Science, and data analytics, are new and nebulas, and takes on different characteristics depending on: The subject matter being analyzed, the maturity of the research, and whether the employed subject specific analytics is descriptive, diagnostic, discoveritive, predictive, or prescriptive, in nature. In addition, in a, thus far, business driven paradigm shift, university curriculums teaching data analytics pertaining to Earth science have, as a whole, lagged behind, and/or have varied in approach. This presentation attempts to breakdown and identify the many activities that Earth Data Scientists, as a profession, encounter, as well as provide case studies of specific Earth Data Scientist and data analytics efforts. I will also address the educational preparation, that best equips future Earth Data Scientists, needed to further Earth science heterogeneous data research and applications analysis. The goal of this presentation is to describe the actual need for Earth Data Scientists and the practical skills to perform Earth science data analytics, thus hoping to initiate discussion addressing a baseline set of needed expertise for educating future Earth Data Scientists.
A novel analytical description of periodic volume coil geometries in MRI
NASA Astrophysics Data System (ADS)
Koh, D.; Felder, J.; Shah, N. J.
2018-03-01
MRI volume coils can be represented by equivalent lumped element circuits and for a variety of these circuit configurations analytical design equations have been presented. The unification of several volume coil topologies results in a two-dimensional gridded equivalent lumped element circuit which compromises the birdcage resonator, its multiple endring derivative but also novel structures like the capacitive coupled ring resonator. The theory section analyzes a general two-dimensional circuit by noting that its current distribution can be decomposed into a longitudinal and an azimuthal dependency. This can be exploited to compare the current distribution with a transfer function of filter circuits along one direction. The resonances of the transfer function coincide with the resonance of the volume resonator and the simple analytical solution can be used as a design equation. The proposed framework is verified experimentally against a novel capacitive coupled ring structure which was derived from the general circuit formulation and is proven to exhibit a dominant homogeneous mode. In conclusion, a unified analytical framework is presented that allows determining the resonance frequency of any volume resonator that can be represented by a two dimensional meshed equivalent circuit.
Charge carrier coherence and Hall effect in organic semiconductors.
Yi, H T; Gartstein, Y N; Podzorov, V
2016-03-30
Hall effect measurements are important for elucidating the fundamental charge transport mechanisms and intrinsic mobility in organic semiconductors. However, Hall effect studies frequently reveal an unconventional behavior that cannot be readily explained with the simple band-semiconductor Hall effect model. Here, we develop an analytical model of Hall effect in organic field-effect transistors in a regime of coexisting band and hopping carriers. The model, which is supported by the experiments, is based on a partial Hall voltage compensation effect, occurring because hopping carriers respond to the transverse Hall electric field and drift in the direction opposite to the Lorentz force acting on band carriers. We show that this can lead in particular to an underdeveloped Hall effect observed in organic semiconductors with substantial off-diagonal thermal disorder. Our model captures the main features of Hall effect in a variety of organic semiconductors and provides an analytical description of Hall mobility, carrier density and carrier coherence factor.
21 CFR 314.50 - Content and format of an application.
Code of Federal Regulations, 2013 CFR
2013-04-01
... the protocol and a description of the statistical analyses used to evaluate the study. If the study... application: (i) Three copies of the analytical procedures and related descriptive information contained in... the samples and to validate the applicant's analytical procedures. The related descriptive information...
21 CFR 314.50 - Content and format of an application.
Code of Federal Regulations, 2012 CFR
2012-04-01
... the protocol and a description of the statistical analyses used to evaluate the study. If the study... application: (i) Three copies of the analytical procedures and related descriptive information contained in... the samples and to validate the applicant's analytical procedures. The related descriptive information...
21 CFR 314.50 - Content and format of an application.
Code of Federal Regulations, 2014 CFR
2014-04-01
... the protocol and a description of the statistical analyses used to evaluate the study. If the study... application: (i) Three copies of the analytical procedures and related descriptive information contained in... the samples and to validate the applicant's analytical procedures. The related descriptive information...
21 CFR 314.50 - Content and format of an application.
Code of Federal Regulations, 2011 CFR
2011-04-01
... the protocol and a description of the statistical analyses used to evaluate the study. If the study... application: (i) Three copies of the analytical procedures and related descriptive information contained in... the samples and to validate the applicant's analytical procedures. The related descriptive information...
21 CFR 314.50 - Content and format of an application.
Code of Federal Regulations, 2010 CFR
2010-04-01
... the protocol and a description of the statistical analyses used to evaluate the study. If the study... application: (i) Three copies of the analytical procedures and related descriptive information contained in... the samples and to validate the applicant's analytical procedures. The related descriptive information...
Analytical Studies on the Synchronization of a Network of Linearly-Coupled Simple Chaotic Systems
NASA Astrophysics Data System (ADS)
Sivaganesh, G.; Arulgnanam, A.; Seethalakshmi, A. N.; Selvaraj, S.
2018-05-01
We present explicit generalized analytical solutions for a network of linearly-coupled simple chaotic systems. Analytical solutions are obtained for the normalized state equations of a network of linearly-coupled systems driven by a common chaotic drive system. Two parameter bifurcation diagrams revealing the various hidden synchronization regions, such as complete, phase and phase-lag synchronization are identified using the analytical results. The synchronization dynamics and their stability are studied using phase portraits and the master stability function, respectively. Further, experimental results for linearly-coupled simple chaotic systems are presented to confirm the analytical results. The synchronization dynamics of a network of chaotic systems studied analytically is reported for the first time.
NASA Technical Reports Server (NTRS)
Migneault, G. E.
1979-01-01
Emulation techniques applied to the analysis of the reliability of highly reliable computer systems for future commercial aircraft are described. The lack of credible precision in reliability estimates obtained by analytical modeling techniques is first established. The difficulty is shown to be an unavoidable consequence of: (1) a high reliability requirement so demanding as to make system evaluation by use testing infeasible; (2) a complex system design technique, fault tolerance; (3) system reliability dominated by errors due to flaws in the system definition; and (4) elaborate analytical modeling techniques whose precision outputs are quite sensitive to errors of approximation in their input data. Next, the technique of emulation is described, indicating how its input is a simple description of the logical structure of a system and its output is the consequent behavior. Use of emulation techniques is discussed for pseudo-testing systems to evaluate bounds on the parameter values needed for the analytical techniques. Finally an illustrative example is presented to demonstrate from actual use the promise of the proposed application of emulation.
Analysis of mode-locked and intracavity frequency-doubled Nd:YAG laser
NASA Technical Reports Server (NTRS)
Siegman, A. E.; Heritier, J.-M.
1980-01-01
The paper presents analytical and computer studies of the CW mode-locked and intracavity frequency-doubled Nd:YAG laser which provide new insight into the operation, including the detuning behavior, of this type of laser. Computer solutions show that the steady-state pulse shape for this laser is much closer to a truncated cosine than to a Gaussian; there is little spectral broadening for on-resonance operation; and the chirp is negligible. This leads to a simplified analytical model carried out entirely in the time domain, with atomic linewidth effects ignored. Simple analytical results for on-resonance pulse shape, pulse width, signal intensity, and harmonic conversion efficiency in terms of basic laser parameters are derived from this model. A simplified physical description of the detuning behavior is also developed. Agreement is found with experimental studies showing that the pulsewidth decreases as the modulation frequency is detuned off resonance; the harmonic power output initially increases and then decreases; and the pulse shape develops a sharp-edged asymmetry of opposite sense for opposite signs of detuning.
Barros, Wilson; Gochberg, Daniel F.; Gore, John C.
2009-01-01
The description of the nuclear magnetic resonance magnetization dynamics in the presence of long-range dipolar interactions, which is based upon approximate solutions of Bloch–Torrey equations including the effect of a distant dipolar field, has been revisited. New experiments show that approximate analytic solutions have a broader regime of validity as well as dependencies on pulse-sequence parameters that seem to have been overlooked. In order to explain these experimental results, we developed a new method consisting of calculating the magnetization via an iterative formalism where both diffusion and distant dipolar field contributions are treated as integral operators incorporated into the Bloch–Torrey equations. The solution can be organized as a perturbative series, whereby access to higher order terms allows one to set better boundaries on validity regimes for analytic first-order approximations. Finally, the method legitimizes the use of simple analytic first-order approximations under less demanding experimental conditions, it predicts new pulse-sequence parameter dependencies for the range of validity, and clarifies weak points in previous calculations. PMID:19425789
Goedecke, Thomas; Morales, Daniel R; Pacurariu, Alexandra; Kurz, Xavier
2018-03-01
Evaluating the public health impact of regulatory interventions is important but there is currently no common methodological approach to guide this evaluation. This systematic review provides a descriptive overview of the analytical methods for impact research. We searched MEDLINE and EMBASE for articles with an empirical analysis evaluating the impact of European Union or non-European Union regulatory actions to safeguard public health published until March 2017. References from systematic reviews and articles from other known sources were added. Regulatory interventions, data sources, outcomes of interest, methodology and key findings were extracted. From 1246 screened articles, 229 were eligible for full-text review and 153 articles in English language were included in the descriptive analysis. Over a third of articles studied analgesics and antidepressants. Interventions most frequently evaluated are regulatory safety communications (28.8%), black box warnings (23.5%) and direct healthcare professional communications (10.5%); 55% of studies measured changes in drug utilization patterns, 27% evaluated health outcomes, and 18% targeted knowledge, behaviour or changes in clinical practice. Unintended consequences like switching therapies or spill-over effects were rarely evaluated. Two-thirds used before-after time series and 15.7% before-after cross-sectional study designs. Various analytical approaches were applied including interrupted time series regression (31.4%), simple descriptive analysis (28.8%) and descriptive analysis with significance tests (23.5%). Whilst impact evaluation of pharmacovigilance and product-specific regulatory interventions is increasing, the marked heterogeneity in study conduct and reporting highlights the need for scientific guidance to ensure robust methodologies are applied and systematic dissemination of results occurs. © 2017 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.
Generalized Born Models of Macromolecular Solvation Effects
NASA Astrophysics Data System (ADS)
Bashford, Donald; Case, David A.
2000-10-01
It would often be useful in computer simulations to use a simple description of solvation effects, instead of explicitly representing the individual solvent molecules. Continuum dielectric models often work well in describing the thermodynamic aspects of aqueous solvation, and approximations to such models that avoid the need to solve the Poisson equation are attractive because of their computational efficiency. Here we give an overview of one such approximation, the generalized Born model, which is simple and fast enough to be used for molecular dynamics simulations of proteins and nucleic acids. We discuss its strengths and weaknesses, both for its fidelity to the underlying continuum model and for its ability to replace explicit consideration of solvent molecules in macromolecular simulations. We focus particularly on versions of the generalized Born model that have a pair-wise analytical form, and therefore fit most naturally into conventional molecular mechanics calculations.
A Simple Numerical Procedure for the Simulation of "Lifelike" Linear-Sweep Voltammograms
NASA Astrophysics Data System (ADS)
Bozzini, Benedetto P.
2000-01-01
Practical linear-sweep voltammograms seldom resemble the theoretical ones shown in textbooks. This is because several phenomena (activation, mass transport, ohmic resistance) control the kinetics over different potential ranges scanned during the potential sweep. These effects are generally treated separately in the didactic literature, yet they have never been "assembled" in a way that allows the educational use of real experiments. This makes linear-sweep voltammetric experiments almost unusable in the teaching of physical chemistry. A simple approach to the classroom description of "lifelike" experimental results is proposed in this paper. Analytical expressions of linear sweep voltammograms are provided. The actual numerical evaluations can be carried out with a pocket calculator. Two typical examples are executed and comparison with experimental data is described. This approach to teaching electrode kinetics has proved an effective tool to provide students with an insight into the effects of electrochemical parameters and operating conditions.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cimpoesu, Dorin, E-mail: cdorin@uaic.ro; Stoleriu, Laurentiu; Stancu, Alexandru
2013-12-14
We propose a generalized Stoner-Wohlfarth (SW) type model to describe various experimentally observed angular dependencies of the switching field in non-single-domain magnetic particles. Because the nonuniform magnetic states are generally characterized by complicated spin configurations with no simple analytical description, we maintain the macrospin hypothesis and we phenomenologically include the effects of nonuniformities only in the anisotropy energy, preserving as much as possible the elegance of SW model, the concept of critical curve and its geometric interpretation. We compare the results obtained with our model with full micromagnetic simulations in order to evaluate the performance and limits of our approach.
NASA Astrophysics Data System (ADS)
Polotto, Franciele; Drigo Filho, Elso; Chahine, Jorge; Oliveira, Ronaldo Junio de
2018-03-01
This work developed analytical methods to explore the kinetics of the time-dependent probability distributions over thermodynamic free energy profiles of protein folding and compared the results with simulation. The Fokker-Planck equation is mapped onto a Schrödinger-type equation due to the well-known solutions of the latter. Through a semi-analytical description, the supersymmetric quantum mechanics formalism is invoked and the time-dependent probability distributions are obtained with numerical calculations by using the variational method. A coarse-grained structure-based model of the two-state protein Tm CSP was simulated at a Cα level of resolution and the thermodynamics and kinetics were fully characterized. Analytical solutions from non-equilibrium conditions were obtained with the simulated double-well free energy potential and kinetic folding times were calculated. It was found that analytical folding time as a function of temperature agrees, quantitatively, with simulations and experiments from the literature of Tm CSP having the well-known 'U' shape of the Chevron Plots. The simple analytical model developed in this study has a potential to be used by theoreticians and experimentalists willing to explore, quantitatively, rates and the kinetic behavior of their system by informing the thermally activated barrier. The theory developed describes a stochastic process and, therefore, can be applied to a variety of biological as well as condensed-phase two-state systems.
Spacecraft formation control using analytical finite-duration approaches
NASA Astrophysics Data System (ADS)
Ben Larbi, Mohamed Khalil; Stoll, Enrico
2018-03-01
This paper derives a control concept for formation flight (FF) applications assuming circular reference orbits. The paper focuses on a general impulsive control concept for FF which is then extended to the more realistic case of non-impulsive thrust maneuvers. The control concept uses a description of the FF in relative orbital elements (ROE) instead of the classical Cartesian description since the ROE provide a direct insight into key aspects of the relative motion and are particularly suitable for relative orbit control purposes and collision avoidance analysis. Although Gauss' variational equations have been first derived to offer a mathematical tool for processing orbit perturbations, they are suitable for several different applications. If the perturbation acceleration is due to a control thrust, Gauss' variational equations show the effect of such a control thrust on the Keplerian orbital elements. Integrating the Gauss' variational equations offers a direct relation between velocity increments in the local vertical local horizontal frame and the subsequent change of Keplerian orbital elements. For proximity operations, these equations can be generalized from describing the motion of single spacecraft to the description of the relative motion of two spacecraft. This will be shown for impulsive and finite-duration maneuvers. Based on that, an analytical tool to estimate the error induced through impulsive maneuver planning is presented. The resulting control schemes are simple and effective and thus also suitable for on-board implementation. Simulations show that the proposed concept improves the timing of the thrust maneuver executions and thus reduces the residual error of the formation control.
Charge carrier coherence and Hall effect in organic semiconductors
Yi, H. T.; Gartstein, Y. N.; Podzorov, V.
2016-03-30
Hall effect measurements are important for elucidating the fundamental charge transport mechanisms and intrinsic mobility in organic semiconductors. However, Hall effect studies frequently reveal an unconventional behavior that cannot be readily explained with the simple band-semiconductor Hall effect model. Here, we develop an analytical model of Hall effect in organic field-effect transistors in a regime of coexisting band and hopping carriers. The model, which is supported by the experiments, is based on a partial Hall voltage compensation effect, occurring because hopping carriers respond to the transverse Hall electric field and drift in the direction opposite to the Lorentz force actingmore » on band carriers. We show that this can lead in particular to an underdeveloped Hall effect observed in organic semiconductors with substantial off-diagonal thermal disorder. Lastly, our model captures the main features of Hall effect in a variety of organic semiconductors and provides an analytical description of Hall mobility, carrier density and carrier coherence factor.« less
Selection by consequences, behavioral evolution, and the price equation.
Baum, William M
2017-05-01
Price's equation describes evolution across time in simple mathematical terms. Although it is not a theory, but a derived identity, it is useful as an analytical tool. It affords lucid descriptions of genetic evolution, cultural evolution, and behavioral evolution (often called "selection by consequences") at different levels (e.g., individual vs. group) and at different time scales (local and extended). The importance of the Price equation for behavior analysis lies in its ability to precisely restate selection by consequences, thereby restating, or even replacing, the law of effect. Beyond this, the equation may be useful whenever one regards ontogenetic behavioral change as evolutionary change, because it describes evolutionary change in abstract, general terms. As an analytical tool, the behavioral Price equation is an excellent aid in understanding how behavior changes within organisms' lifetimes. For example, it illuminates evolution of response rate, analyses of choice in concurrent schedules, negative contingencies, and dilemmas of self-control. © 2017 Society for the Experimental Analysis of Behavior.
NASA Astrophysics Data System (ADS)
Ludescher, J.; Tsallis, C.; Bunde, A.
2011-09-01
We consider 16 representative financial records (stocks, indices, commodities, and exchange rates) and study the distribution PQ(r) of the interoccurrence times r between daily losses below negative thresholds -Q, for fixed mean interoccurrence time RQ. We find that in all cases, PQ(r) follows the form PQ(r)~1/[(1+(q- 1)βr]1/(q-1), where β and q are universal constants that depend only on RQ, but not on a specific asset. While β depends only slightly on RQ, the q-value increases logarithmically with RQ, q=1+q0 ln(RQ/2), such that for RQ→2, PQ(r) approaches a simple exponential, PQ(r)cong2-r. The fact that PQ does not scale with RQ is due to the multifractality of the financial markets. The analytic form of PQ allows also to estimate both the risk function and the Value-at-Risk, and thus to improve the estimation of the financial risk.
A Log Logistic Survival Model Applied to Hypobaric Decompression Sickness
NASA Technical Reports Server (NTRS)
Conkin, Johnny
2001-01-01
Decompression sickness (DCS) is a complex, multivariable problem. A mathematical description or model of the likelihood of DCS requires a large amount of quality research data, ideas on how to define a decompression dose using physical and physiological variables, and an appropriate analytical approach. It also requires a high-performance computer with specialized software. I have used published DCS data to develop my decompression doses, which are variants of equilibrium expressions for evolved gas plus other explanatory variables. My analytical approach is survival analysis, where the time of DCS occurrence is modeled. My conclusions can be applied to simple hypobaric decompressions - ascents lasting from 5 to 30 minutes - and, after minutes to hours, to denitrogenation (prebreathing). They are also applicable to long or short exposures, and can be used whether the sufferer of DCS is at rest or exercising at altitude. Ultimately I would like my models to be applied to astronauts to reduce the risk of DCS during spacewalks, as well as to future spaceflight crews on the Moon and Mars.
Charge carrier coherence and Hall effect in organic semiconductors
Yi, H. T.; Gartstein, Y. N.; Podzorov, V.
2016-01-01
Hall effect measurements are important for elucidating the fundamental charge transport mechanisms and intrinsic mobility in organic semiconductors. However, Hall effect studies frequently reveal an unconventional behavior that cannot be readily explained with the simple band-semiconductor Hall effect model. Here, we develop an analytical model of Hall effect in organic field-effect transistors in a regime of coexisting band and hopping carriers. The model, which is supported by the experiments, is based on a partial Hall voltage compensation effect, occurring because hopping carriers respond to the transverse Hall electric field and drift in the direction opposite to the Lorentz force acting on band carriers. We show that this can lead in particular to an underdeveloped Hall effect observed in organic semiconductors with substantial off-diagonal thermal disorder. Our model captures the main features of Hall effect in a variety of organic semiconductors and provides an analytical description of Hall mobility, carrier density and carrier coherence factor. PMID:27025354
Bauermeister, Christoph; Schwalger, Tilo; Russell, David F; Neiman, Alexander B; Lindner, Benjamin
2013-01-01
Stochastic signals with pronounced oscillatory components are frequently encountered in neural systems. Input currents to a neuron in the form of stochastic oscillations could be of exogenous origin, e.g. sensory input or synaptic input from a network rhythm. They shape spike firing statistics in a characteristic way, which we explore theoretically in this report. We consider a perfect integrate-and-fire neuron that is stimulated by a constant base current (to drive regular spontaneous firing), along with Gaussian narrow-band noise (a simple example of stochastic oscillations), and a broadband noise. We derive expressions for the nth-order interval distribution, its variance, and the serial correlation coefficients of the interspike intervals (ISIs) and confirm these analytical results by computer simulations. The theory is then applied to experimental data from electroreceptors of paddlefish, which have two distinct types of internal noisy oscillators, one forcing the other. The theory provides an analytical description of their afferent spiking statistics during spontaneous firing, and replicates a pronounced dependence of ISI serial correlation coefficients on the relative frequency of the driving oscillations, and furthermore allows extraction of certain parameters of the intrinsic oscillators embedded in these electroreceptors.
NASA Astrophysics Data System (ADS)
Poirier, M.
2015-06-01
Density effects in ionized matter require particular attention since they modify energies, wavefunctions and transition rates with respect to the isolated-ion situation. The approach chosen in this paper is based on the ion-sphere model involving a Thomas-Fermi-like description for free electrons, the bound electrons being described by a full quantum mechanical formalism. This permits to deal with plasmas out of thermal local equilibrium, assuming only a Maxwell distribution for free electrons. For H-like ions, such a theory provides simple and rather accurate analytical approximations for the potential created by free electrons. Emphasis is put on the plasma potential rather than on the electron density, since the energies and wavefunctions depend directly on this potential. Beyond the uniform electron gas model, temperature effects may be analyzed. In the case of H-like ions, this formalism provides analytical perturbative expressions for the energies, wavefunctions and transition rates. Explicit expressions are given in the case of maximum orbital quantum number, and compare satisfactorily with results from a direct integration of the radial Schrödinger equation. Some formulas for lower orbital quantum numbers are also proposed.
Suba, Dávid; Urbányi, Zoltán; Salgó, András
2016-10-01
Capillary electrophoresis techniques are widely used in the analytical biotechnology. Different electrophoretic techniques are very adequate tools to monitor size-and charge heterogenities of protein drugs. Method descriptions and development studies of capillary zone electrophoresis (CZE) have been described in literature. Most of them are performed based on the classical one-factor-at-time (OFAT) approach. In this study a very simple method development approach is described for capillary zone electrophoresis: a "two-phase-four-step" approach is introduced which allows a rapid, iterative method development process and can be a good platform for CZE method. In every step the current analytical target profile and an appropriate control strategy were established to monitor the current stage of development. A very good platform was established to investigate intact and digested protein samples. Commercially available monoclonal antibody was chosen as model protein for the method development study. The CZE method was qualificated after the development process and the results were presented. The analytical system stability was represented by the calculated RSD% value of area percentage and migration time of the selected peaks (<0.8% and <5%) during the intermediate precision investigation. Copyright © 2016 Elsevier B.V. All rights reserved.
Mesoscopic description of random walks on combs
NASA Astrophysics Data System (ADS)
Méndez, Vicenç; Iomin, Alexander; Campos, Daniel; Horsthemke, Werner
2015-12-01
Combs are a simple caricature of various types of natural branched structures, which belong to the category of loopless graphs and consist of a backbone and branches. We study continuous time random walks on combs and present a generic method to obtain their transport properties. The random walk along the branches may be biased, and we account for the effect of the branches by renormalizing the waiting time probability distribution function for the motion along the backbone. We analyze the overall diffusion properties along the backbone and find normal diffusion, anomalous diffusion, and stochastic localization (diffusion failure), respectively, depending on the characteristics of the continuous time random walk along the branches, and compare our analytical results with stochastic simulations.
Mergers of Non-spinning Black-hole Binaries: Gravitational Radiation Characteristics
NASA Technical Reports Server (NTRS)
Baker, John G.; Boggs, William D.; Centrella, Joan; Kelly, Bernard J.; McWilliams, Sean T.; vanMeter, James R.
2008-01-01
We present a detailed descriptive analysis of the gravitational radiation from black-hole binary mergers of non-spinning black holes, based on numerical simulations of systems varying from equal-mass to a 6:1 mass ratio. Our primary goal is to present relatively complete information about the waveforms, including all the leading multipolar components, to interested researchers. In our analysis, we pursue the simplest physical description of the dominant features in the radiation, providing an interpretation of the waveforms in terms of an implicit rotating source. This interpretation applies uniformly to the full wavetrain, from inspiral through ringdown. We emphasize strong relationships among the l = m modes that persist through the full wavetrain. Exploring the structure of the waveforms in more detail, we conduct detailed analytic fitting of the late-time frequency evolution, identifying a key quantitative feature shared by the l = m modes among all mass-ratios. We identify relationships, with a simple interpretation in terms of the implicit rotating source, among the evolution of frequency and amplitude, which hold for the late-time radiation. These detailed relationships provide sufficient information about the late-time radiation to yield a predictive model for the late-time waveforms, an alternative to the common practice of modeling by a sum of quasinormal mode overtones. We demonstrate an application of this in a new effective-one-body-based analytic waveform model.
Mergers of nonspinning black-hole binaries: Gravitational radiation characteristics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Baker, John G.; Centrella, Joan; Kelly, Bernard J.
2008-08-15
We present a detailed descriptive analysis of the gravitational radiation from black-hole binary mergers of nonspinning black holes, based on numerical simulations of systems varying from equal mass to a 6 ratio 1 mass ratio. Our primary goal is to present relatively complete information about the waveforms, including all the leading multipolar components, to interested researchers. In our analysis, we pursue the simplest physical description of the dominant features in the radiation, providing an interpretation of the waveforms in terms of an implicit rotating source. This interpretation applies uniformly to the full wave train, from inspiral through ringdown. We emphasizemore » strong relationships among the l=m modes that persist through the full wave train. Exploring the structure of the waveforms in more detail, we conduct detailed analytic fitting of the late-time frequency evolution, identifying a key quantitative feature shared by the l=m modes among all mass ratios. We identify relationships, with a simple interpretation in terms of the implicit rotating source, among the evolution of frequency and amplitude, which hold for the late-time radiation. These detailed relationships provide sufficient information about the late-time radiation to yield a predictive model for the late-time waveforms, an alternative to the common practice of modeling by a sum of quasinormal mode overtones. We demonstrate an application of this in a new effective-one-body-based analytic waveform model.« less
Developing the Polynomial Expressions for Fields in the ITER Tokamak
NASA Astrophysics Data System (ADS)
Sharma, Stephen
2017-10-01
The two most important problems to be solved in the development of working nuclear fusion power plants are: sustained partial ignition and turbulence. These two phenomena are the subject of research and investigation through the development of analytic functions and computational models. Ansatz development through Gaussian wave-function approximations, dielectric quark models, field solutions using new elliptic functions, and better descriptions of the polynomials of the superconducting current loops are the critical theoretical developments that need to be improved. Euler-Lagrange equations of motion in addition to geodesic formulations generate the particle model which should correspond to the Dirac dispersive scattering coefficient calculations and the fluid plasma model. Feynman-Hellman formalism and Heaviside step functional forms are introduced to the fusion equations to produce simple expressions for the kinetic energy and loop currents. Conclusively, a polynomial description of the current loops, the Biot-Savart field, and the Lagrangian must be uncovered before there can be an adequate computational and iterative model of the thermonuclear plasma.
Expressions for Fields in the ITER Tokamak
NASA Astrophysics Data System (ADS)
Sharma, Stephen
2017-10-01
The two most important problems to be solved in the development of working nuclear fusion power plants are: sustained partial ignition and turbulence. These two phenomenon are the subject of research and investigation through the development of analytic functions and computational models. Ansatz development through Gaussian wave-function approximations, dielectric quark models, field solutions using new elliptic functions, and better descriptions of the polynomials of the superconducting current loops are the critical theoretical developments that need to be improved. Euler-Lagrange equations of motion in addition to geodesic formulations generate the particle model which should correspond to the Dirac dispersive scattering coefficient calculations and the fluid plasma model. Feynman-Hellman formalism and Heaviside step functional forms are introduced to the fusion equations to produce simple expressions for the kinetic energy and loop currents. Conclusively, a polynomial description of the current loops, the Biot-Savart field, and the Lagrangian must be uncovered before there can be an adequate computational and iterative model of the thermonuclear plasma.
A new approach to analytic, non-perturbative and gauge-invariant QCD
NASA Astrophysics Data System (ADS)
Fried, H. M.; Grandou, T.; Sheu, Y.-M.
2012-11-01
Following a previous calculation of quark scattering in eikonal approximation, this paper presents a new, analytic and rigorous approach to the calculation of QCD phenomena. In this formulation a basic distinction between the conventional "idealistic" description of QCD and a more "realistic" description is brought into focus by a non-perturbative, gauge-invariant evaluation of the Schwinger solution for the QCD generating functional in terms of the exact Fradkin representations of Green's functional G(x,y|A) and the vacuum functional L[A]. Because quarks exist asymptotically only in bound states, their transverse coordinates can never be measured with arbitrary precision; the non-perturbative neglect of this statement leads to obstructions that are easily corrected by invoking in the basic Lagrangian a probability amplitude which describes such transverse imprecision. The second result of this non-perturbative analysis is the appearance of a new and simplifying output called "Effective Locality", in which the interactions between quarks by the exchange of a "gluon bundle"-which "bundle" contains an infinite number of gluons, including cubic and quartic gluon interactions-display an exact locality property that reduces the several functional integrals of the formulation down to a set of ordinary integrals. It should be emphasized that "non-perturbative" here refers to the effective summation of all gluons between a pair of quark lines-which may be the same quark line, as in a self-energy graph-but does not (yet) include a summation over all closed-quark loops which are tied by gluon-bundle exchange to the rest of the "Bundle Diagram". As an example of the power of these methods we offer as a first analytic calculation the quark-antiquark binding potential of a pion, and the corresponding three-quark binding potential of a nucleon, obtained in a simple way from relevant eikonal scattering approximations. A second calculation, analytic, non-perturbative and gauge-invariant, of a nucleon-nucleon binding potential to form a model deuteron, will appear separately.
Validation of the replica trick for simple models
NASA Astrophysics Data System (ADS)
Shinzato, Takashi
2018-04-01
We discuss the replica analytic continuation using several simple models in order to prove mathematically the validity of the replica analysis, which is used in a wide range of fields related to large-scale complex systems. While replica analysis consists of two analytical techniques—the replica trick (or replica analytic continuation) and the thermodynamical limit (and/or order parameter expansion)—we focus our study on replica analytic continuation, which is the mathematical basis of the replica trick. We apply replica analysis to solve a variety of analytical models, and examine the properties of replica analytic continuation. Based on the positive results for these models we propose that replica analytic continuation is a robust procedure in replica analysis.
Beyramysoltan, Samira; Abdollahi, Hamid; Rajkó, Róbert
2014-05-27
Analytical self-modeling curve resolution (SMCR) methods resolve data sets to a range of feasible solutions using only non-negative constraints. The Lawton-Sylvestre method was the first direct method to analyze a two-component system. It was generalized as a Borgen plot for determining the feasible regions in three-component systems. It seems that a geometrical view is required for considering curve resolution methods, because the complicated (only algebraic) conceptions caused a stop in the general study of Borgen's work for 20 years. Rajkó and István revised and elucidated the principles of existing theory in SMCR methods and subsequently introduced computational geometry tools for developing an algorithm to draw Borgen plots in three-component systems. These developments are theoretical inventions and the formulations are not always able to be given in close form or regularized formalism, especially for geometric descriptions, that is why several algorithms should have been developed and provided for even the theoretical deductions and determinations. In this study, analytical SMCR methods are revised and described using simple concepts. The details of a drawing algorithm for a developmental type of Borgen plot are given. Additionally, for the first time in the literature, equality and unimodality constraints are successfully implemented in the Lawton-Sylvestre method. To this end, a new state-of-the-art procedure is proposed to impose equality constraint in Borgen plots. Two- and three-component HPLC-DAD data set were simulated and analyzed by the new analytical curve resolution methods with and without additional constraints. Detailed descriptions and explanations are given based on the obtained abstract spaces. Copyright © 2014 Elsevier B.V. All rights reserved.
Improved multidimensional semiclassical tunneling theory.
Wagner, Albert F
2013-12-12
We show that the analytic multidimensional semiclassical tunneling formula of Miller et al. [Miller, W. H.; Hernandez, R.; Handy, N. C.; Jayatilaka, D.; Willets, A. Chem. Phys. Lett. 1990, 172, 62] is qualitatively incorrect for deep tunneling at energies well below the top of the barrier. The origin of this deficiency is that the formula uses an effective barrier weakly related to the true energetics but correctly adjusted to reproduce the harmonic description and anharmonic corrections of the reaction path at the saddle point as determined by second order vibrational perturbation theory. We present an analytic improved semiclassical formula that correctly includes energetic information and allows a qualitatively correct representation of deep tunneling. This is done by constructing a three segment composite Eckart potential that is continuous everywhere in both value and derivative. This composite potential has an analytic barrier penetration integral from which the semiclassical action can be derived and then used to define the semiclassical tunneling probability. The middle segment of the composite potential by itself is superior to the original formula of Miller et al. because it incorporates the asymmetry of the reaction barrier produced by the known reaction exoergicity. Comparison of the semiclassical and exact quantum tunneling probability for the pure Eckart potential suggests a simple threshold multiplicative factor to the improved formula to account for quantum effects very near threshold not represented by semiclassical theory. The deep tunneling limitations of the original formula are echoed in semiclassical high-energy descriptions of bound vibrational states perpendicular to the reaction path at the saddle point. However, typically ab initio energetic information is not available to correct it. The Supporting Information contains a Fortran code, test input, and test output that implements the improved semiclassical tunneling formula.
NASA Astrophysics Data System (ADS)
Sabirov, K.; Rakhmanov, S.; Matrasulov, D.; Susanto, H.
2018-04-01
We consider the stationary sine-Gordon equation on metric graphs with simple topologies. Exact analytical solutions are obtained for different vertex boundary conditions. It is shown that the method can be extended for tree and other simple graph topologies. Applications of the obtained results to branched planar Josephson junctions and Josephson junctions with tricrystal boundaries are discussed.
21 CFR 314.94 - Content and format of an abbreviated application.
Code of Federal Regulations, 2014 CFR
2014-04-01
... bioequivalence study contained in the abbreviated new drug application, a description of the analytical and... exclusivity under section 505(j)(5)(F) of the act. (9) Chemistry, manufacturing, and controls. (i) The... the act and one copy of the analytical procedures and descriptive information needed by FDA's...
21 CFR 314.94 - Content and format of an abbreviated application.
Code of Federal Regulations, 2013 CFR
2013-04-01
... bioequivalence study contained in the abbreviated new drug application, a description of the analytical and... exclusivity under section 505(j)(5)(F) of the act. (9) Chemistry, manufacturing, and controls. (i) The... the act and one copy of the analytical procedures and descriptive information needed by FDA's...
New Tools to Prepare ACE Cross-section Files for MCNP Analytic Test Problems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brown, Forrest B.
Monte Carlo calculations using one-group cross sections, multigroup cross sections, or simple continuous energy cross sections are often used to: (1) verify production codes against known analytical solutions, (2) verify new methods and algorithms that do not involve detailed collision physics, (3) compare Monte Carlo calculation methods with deterministic methods, and (4) teach fundamentals to students. In this work we describe 2 new tools for preparing the ACE cross-section files to be used by MCNP ® for these analytic test problems, simple_ace.pl and simple_ace_mg.pl.
Modeling of hybrid vehicle fuel economy and fuel engine efficiency
NASA Astrophysics Data System (ADS)
Wu, Wei
"Near-CV" (i.e., near-conventional vehicle) hybrid vehicles, with an internal combustion engine, and a supplementary storage with low-weight, low-energy but high-power capacity, are analyzed. This design avoids the shortcoming of the "near-EV" and the "dual-mode" hybrid vehicles that need a large energy storage system (in terms of energy capacity and weight). The small storage is used to optimize engine energy management and can provide power when needed. The energy advantage of the "near-CV" design is to reduce reliance on the engine at low power, to enable regenerative braking, and to provide good performance with a small engine. The fuel consumption of internal combustion engines, which might be applied to hybrid vehicles, is analyzed by building simple analytical models that reflect the engines' energy loss characteristics. Both diesel and gasoline engines are modeled. The simple analytical models describe engine fuel consumption at any speed and load point by describing the engine's indicated efficiency and friction. The engine's indicated efficiency and heat loss are described in terms of several easy-to-obtain engine parameters, e.g., compression ratio, displacement, bore and stroke. Engine friction is described in terms of parameters obtained by fitting available fuel measurements on several diesel and spark-ignition engines. The engine models developed are shown to conform closely to experimental fuel consumption and motored friction data. A model of the energy use of "near-CV" hybrid vehicles with different storage mechanism is created, based on simple algebraic description of the components. With powertrain downsizing and hybridization, a "near-CV" hybrid vehicle can obtain a factor of approximately two in overall fuel efficiency (mpg) improvement, without considering reductions in the vehicle load.
ERIC Educational Resources Information Center
Johannessen, Kim
2010-01-01
An analytic approximation of the solution to the differential equation describing the oscillations of a simple pendulum at large angles and with initial velocity is discussed. In the derivation, a sinusoidal approximation has been applied, and an analytic formula for the large-angle period of the simple pendulum is obtained, which also includes…
40 CFR 91.414 - Raw gaseous exhaust sampling and analytical system description.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Raw gaseous exhaust sampling and... Gaseous Exhaust Test Procedures § 91.414 Raw gaseous exhaust sampling and analytical system description... the component systems. (g) The following requirements must be incorporated in each system used for raw...
40 CFR 91.414 - Raw gaseous exhaust sampling and analytical system description.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Raw gaseous exhaust sampling and... Gaseous Exhaust Test Procedures § 91.414 Raw gaseous exhaust sampling and analytical system description... the component systems. (g) The following requirements must be incorporated in each system used for raw...
40 CFR 90.421 - Dilute gaseous exhaust sampling and analytical system description.
Code of Federal Regulations, 2011 CFR
2011-07-01
... filter and HFID. Determine these gas temperatures by a temperature sensor located immediately upstream of... analytical system description. (a) General. The exhaust gas sampling system described in this section is...-CVS must conform to all of the requirements listed for the exhaust gas PDP-CVS in § 90.420 of this...
40 CFR 90.421 - Dilute gaseous exhaust sampling and analytical system description.
Code of Federal Regulations, 2010 CFR
2010-07-01
... filter and HFID. Determine these gas temperatures by a temperature sensor located immediately upstream of... analytical system description. (a) General. The exhaust gas sampling system described in this section is...-CVS must conform to all of the requirements listed for the exhaust gas PDP-CVS in § 90.420 of this...
A Descriptive-Analytic Study of the Practice Field Behavior of a Winning Female Coach.
ERIC Educational Resources Information Center
Dodds, Patt; Rife, Frank
A winning collegiate field hockey coach was observed across seventeen practice sessions through one complete competitive season. A category system for the event recording of verbal and nonverbal behaviors delivered to the team and to the sixteen individual players produced descriptive-analytic information about relative behavior frequencies for…
Survival of mutations arising during invasions.
Miller, Judith R
2010-03-01
When a neutral mutation arises in an invading population, it quickly either dies out or 'surfs', i.e. it comes to occupy almost all the habitat available at its time of origin. Beneficial mutations can also surf, as can deleterious mutations over finite time spans. We develop descriptive statistical models that quantify the relationship between the probability that a mutation will surf and demographic parameters for a cellular automaton model of surfing. We also provide a simple analytic model that performs well at predicting the probability of surfing for neutral and beneficial mutations in one dimension. The results suggest that factors - possibly including even abiotic factors - that promote invasion success may also increase the probability of surfing and associated adaptive genetic change, conditioned on such success.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Moreno-Bote, Ruben; Parga, Nestor; Center for Theoretical Neuroscience, Center for Neurobiology and Behavior, Columbia University, New York 10032-2695
2006-01-20
An analytical description of the response properties of simple but realistic neuron models in the presence of noise is still lacking. We determine completely up to the second order the firing statistics of a single and a pair of leaky integrate-and-fire neurons receiving some common slowly filtered white noise. In particular, the auto- and cross-correlation functions of the output spike trains of pairs of cells are obtained from an improvement of the adiabatic approximation introduced previously by Moreno-Bote and Parga [Phys. Rev. Lett. 92, 028102 (2004)]. These two functions define the firing variability and firing synchronization between neurons, and aremore » of much importance for understanding neuron communication.« less
Stochastic dynamics of cholera epidemics
NASA Astrophysics Data System (ADS)
Azaele, Sandro; Maritan, Amos; Bertuzzo, Enrico; Rodriguez-Iturbe, Ignacio; Rinaldo, Andrea
2010-05-01
We describe the predictions of an analytically tractable stochastic model for cholera epidemics following a single initial outbreak. The exact model relies on a set of assumptions that may restrict the generality of the approach and yet provides a realm of powerful tools and results. Without resorting to the depletion of susceptible individuals, as usually assumed in deterministic susceptible-infected-recovered models, we show that a simple stochastic equation for the number of ill individuals provides a mechanism for the decay of the epidemics occurring on the typical time scale of seasonality. The model is shown to provide a reasonably accurate description of the empirical data of the 2000/2001 cholera epidemic which took place in the Kwa Zulu-Natal Province, South Africa, with possibly notable epidemiological implications.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Xiong, Hao, E-mail: haoxiong1217@gmail.com; Fan, Yu-Wan; Yang, Xiaoxue
We investigate radiation-pressure induced generation of the frequency components at the difference-sideband in an optomechanical system, which beyond the conventional linearized description of optomechanical interactions between cavity fields and the mechanical oscillation. We analytically calculate amplitudes of these signals, and identify a simple square-root law for both the upper and lower difference-sideband generation which can describe the dependence of the intensities of these signals on the pump power. Further calculation shows that difference-sideband generation can be greatly enhanced via achieving the matching conditions. The effect of difference-sideband generation, which may have potential application for manipulation of light, is especially suitedmore » for on-chip optomechanical devices, where nonlinear optomechanical interaction in the weak coupling regime is within current experimental reach.« less
High precision analytical description of the allowed β spectrum shape
NASA Astrophysics Data System (ADS)
Hayen, Leendert; Severijns, Nathal; Bodek, Kazimierz; Rozpedzik, Dagmara; Mougeot, Xavier
2018-01-01
A fully analytical description of the allowed β spectrum shape is given in view of ongoing and planned measurements. Its study forms an invaluable tool in the search for physics beyond the standard electroweak model and the weak magnetism recoil term. Contributions stemming from finite size corrections, mass effects, and radiative corrections are reviewed. Particular focus is placed on atomic and chemical effects, where the existing description is extended and analytically provided. The effects of QCD-induced recoil terms are discussed, and cross-checks were performed for different theoretical formalisms. Special attention was given to a comparison of the treatment of nuclear structure effects in different formalisms. Corrections were derived for both Fermi and Gamow-Teller transitions, and methods of analytical evaluation thoroughly discussed. In its integrated form, calculated f values were in agreement with the most precise numerical results within the aimed for precision. The need for an accurate evaluation of weak magnetism contributions was stressed, and the possible significance of the oft-neglected induced pseudoscalar interaction was noted. Together with improved atomic corrections, an analytical description was presented of the allowed β spectrum shape accurate to a few parts in 10-4 down to 1 keV for low to medium Z nuclei, thereby extending the work by previous authors by nearly an order of magnitude.
75 FR 62520 - Combined Notice of Filings #1
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-12
... Thursday, October 7, 2010. Docket Numbers: ER10-2541-001. Applicants: Maple Analytics, LLC. Description: Maple Analytics, LLC submits tariff filing per 35: Maple Analytics, LLC Compliance Filing to be...
ERIC Educational Resources Information Center
Namwong, Pithakpong; Jarujamrus, Purim; Amatatongchai, Maliwan; Chairam, Sanoe
2018-01-01
In this article, a low-cost, simple, and rapid fabrication of paper-based analytical devices (PADs) using a wax screen-printing method is reported here. The acid-base reaction is implemented in the simple PADs to demonstrate to students the chemistry concept of a limiting reagent. When a fixed concentration of base reacts with a gradually…
Barreda-García, Susana; Miranda-Castro, Rebeca; de-Los-Santos-Álvarez, Noemí; Miranda-Ordieres, Arturo J; Lobo-Castañón, María Jesús
2018-01-01
Highly sensitive testing of nucleic acids is essential to improve the detection of pathogens, which pose a major threat for public health worldwide. Currently available molecular assays, mainly based on PCR, have a limited utility in point-of-need control or resource-limited settings. Consequently, there is a strong interest in developing cost-effective, robust, and portable platforms for early detection of these harmful microorganisms. Since its description in 2004, isothermal helicase-dependent amplification (HDA) has been successfully applied in the development of novel molecular-based technologies for rapid, sensitive, and selective detection of viruses and bacteria. In this review, we highlight relevant analytical systems using this simple nucleic acid amplification methodology that takes place at a constant temperature and that is readily compatible with microfluidic technologies. Different strategies for monitoring HDA amplification products are described. In addition, we present technological advances for integrating sample preparation, HDA amplification, and detection. Future perspectives and challenges toward point-of-need use not only for clinical diagnosis but also in food safety testing and environmental monitoring are also discussed. Graphical Abstract Expanding the analytical toolbox for the detection of DNA sequences specific of pathogens with isothermal helicase dependent amplification (HDA).
Spontaneous dissipation of elastic energy by self-localizing thermal runaway
NASA Astrophysics Data System (ADS)
Braeck, S.; Podladchikov, Y. Y.; Medvedev, S.
2009-10-01
Thermal runaway instability induced by material softening due to shear heating represents a potential mechanism for mechanical failure of viscoelastic solids. In this work we present a model based on a continuum formulation of a viscoelastic material with Arrhenius dependence of viscosity on temperature and investigate the behavior of the thermal runaway phenomenon by analytical and numerical methods. Approximate analytical descriptions of the problem reveal that onset of thermal runaway instability is controlled by only two dimensionless combinations of physical parameters. Numerical simulations of the model independently verify these analytical results and allow a quantitative examination of the complete time evolutions of the shear stress and the spatial distributions of temperature and displacement during runaway instability. Thus we find that thermal runaway processes may well develop under nonadiabatic conditions. Moreover, nonadiabaticity of the unstable runaway mode leads to continuous and extreme localization of the strain and temperature profiles in space, demonstrating that the thermal runaway process can cause shear banding. Examples of time evolutions of the spatial distribution of the shear displacement between the interior of the shear band and the essentially nondeforming material outside are presented. Finally, a simple relation between evolution of shear stress, displacement, shear-band width, and temperature rise during runaway instability is given.
Selb, Melissa; Gimigliano, Francesca; Prodinger, Birgit; Stucki, Gerold; Pestelli, Germano; Iocco, Maurizio; Boldrini, Paolo
2017-04-01
As part of international efforts to develop and implement national models including the specification of ICF-based clinical data collection tools, the Italian rehabilitation community initiated a project to develop simple, intuitive descriptions of the ICF Rehabilitation Set, highlighting the core concept of each category in user-friendly language. This paper outlines the Italian experience in developing simple, intuitive descriptions of the ICF Rehabilitation Set as an ICF-based clinical data collection tool for Italy. Consensus process. Expert conference. Multidisciplinary group of rehabilitation professionals. The first of a two-stage consensus process involved developing an initial proposal for simple, intuitive descriptions of each ICF Rehabilitation Set category based on descriptions generated in a similar process in China. Stage two involved a consensus conference. Divided into three working groups, participants discussed and voted (vote A) whether the initially proposed descriptions of each ICF Rehabilitation Set category was simple and intuitive enough for use in daily practice. Afterwards the categories with descriptions considered ambiguous i.e. not simple and intuitive enough, were divided among the working groups, who were asked to propose a new description for the allocated categories. These proposals were then voted (vote B) on in a plenary session. The last step of the consensus conference required each working group to develop a new proposal for each and the same categories with descriptions still considered ambiguous. Participants then voted (final vote) for which of the three proposed descriptions they preferred. Nineteen clinicians from diverse rehabilitation disciplines from various regions of Italy participated in the consensus process. Three ICF categories already achieved consensus in vote A, while 20 ICF categories were accepted in vote B. The remaining 7 categories were decided in the final vote. The findings were discussed in light of current efforts toward developing strategies for ICF implementation, specifically for the application of an ICF-based clinical data collection tool, not only for Italy but also for the rest of Europe. Promising as minimal standards for monitoring the impact of interventions and for standardized reporting of functioning as a relevant outcome in rehabilitation.
NASA Astrophysics Data System (ADS)
Roderick, Michael L.; Farquhar, Graham D.
2011-12-01
We use the Budyko framework to calculate catchment-scale evapotranspiration (E) and runoff (Q) as a function of two climatic factors, precipitation (P) and evaporative demand (Eo = 0.75 times the pan evaporation rate), and a third parameter that encodes the catchment properties (n) and modifies how P is partitioned between E and Q. This simple theory accurately predicted the long-term evapotranspiration (E) and runoff (Q) for the Murray-Darling Basin (MDB) in southeast Australia. We extend the theory by developing a simple and novel analytical expression for the effects on E and Q of small perturbations in P, Eo, and n. The theory predicts that a 10% change in P, with all else constant, would result in a 26% change in Q in the MDB. Future climate scenarios (2070-2099) derived using Intergovernmental Panel on Climate Change AR4 climate model output highlight the diversity of projections for P (±30%) with a correspondingly large range in projections for Q (±80%) in the MDB. We conclude with a qualitative description about the impact of changes in catchment properties on water availability and focus on the interaction between vegetation change, increasing atmospheric [CO2], and fire frequency. We conclude that the modern version of the Budyko framework is a useful tool for making simple and transparent estimates of changes in water availability.
Erratum: A Simple, Analytical Model of Collisionless Magnetic Reconnection in a Pair Plasma
NASA Technical Reports Server (NTRS)
Hesse, Michael; Zenitani, Seiji; Kuznetsova, Masha; Klimas, Alex
2011-01-01
The following describes a list of errata in our paper, "A simple, analytical model of collisionless magnetic reconnection in a pair plasma." It supersedes an earlier erratum. We recently discovered an error in the derivation of the outflow-to-inflow density ratio.
Factors affecting dental service quality.
Bahadori, Mohammadkarim; Raadabadi, Mehdi; Ravangard, Ramin; Baldacchino, Donia
2015-01-01
Measuring dental clinic service quality is the first and most important factor in improving care. The quality provided plays an important role in patient satisfaction. The purpose of this paper is to identify factors affecting dental service quality from the patients' viewpoint. This cross-sectional, descriptive-analytical study was conducted in a dental clinic in Tehran between January and June 2014. A sample of 385 patients was selected from two work shifts using stratified sampling proportional to size and simple random sampling methods. The data were collected, a self-administered questionnaire designed for the purpose of the study, based on the Parasuraman and Zeithaml's model of service quality which consisted of two parts: the patients' demographic characteristics and a 30-item questionnaire to measure the five dimensions of the service quality. The collected data were analysed using SPSS 21.0 and Amos 18.0 through some descriptive statistics such as mean, standard deviation, as well as analytical methods, including confirmatory factor. Results showed that the correlation coefficients for all dimensions were higher than 0.5. In this model, assurance (regression weight=0.99) and tangibility (regression weight=0.86) had, respectively, the highest and lowest effects on dental service quality. The Parasuraman and Zeithaml's model is suitable to measure quality in dental services. The variables related to dental services quality have been made according to the model. This is a pioneering study that uses Parasuraman and Zeithaml's model and CFA in a dental setting. This study provides useful insights and guidance for dental service quality assurance.
NASA Astrophysics Data System (ADS)
Donahue, William; Newhauser, Wayne D.; Ziegler, James F.
2016-09-01
Many different approaches exist to calculate stopping power and range of protons and heavy charged particles. These methods may be broadly categorized as physically complete theories (widely applicable and complex) or semi-empirical approaches (narrowly applicable and simple). However, little attention has been paid in the literature to approaches that are both widely applicable and simple. We developed simple analytical models of stopping power and range for ions of hydrogen, carbon, iron, and uranium that spanned intervals of ion energy from 351 keV u-1 to 450 MeV u-1 or wider. The analytical models typically reproduced the best-available evaluated stopping powers within 1% and ranges within 0.1 mm. The computational speed of the analytical stopping power model was 28% faster than a full-theoretical approach. The calculation of range using the analytic range model was 945 times faster than a widely-used numerical integration technique. The results of this study revealed that the new, simple analytical models are accurate, fast, and broadly applicable. The new models require just 6 parameters to calculate stopping power and range for a given ion and absorber. The proposed model may be useful as an alternative to traditional approaches, especially in applications that demand fast computation speed, small memory footprint, and simplicity.
Donahue, William; Newhauser, Wayne D; Ziegler, James F
2016-09-07
Many different approaches exist to calculate stopping power and range of protons and heavy charged particles. These methods may be broadly categorized as physically complete theories (widely applicable and complex) or semi-empirical approaches (narrowly applicable and simple). However, little attention has been paid in the literature to approaches that are both widely applicable and simple. We developed simple analytical models of stopping power and range for ions of hydrogen, carbon, iron, and uranium that spanned intervals of ion energy from 351 keV u(-1) to 450 MeV u(-1) or wider. The analytical models typically reproduced the best-available evaluated stopping powers within 1% and ranges within 0.1 mm. The computational speed of the analytical stopping power model was 28% faster than a full-theoretical approach. The calculation of range using the analytic range model was 945 times faster than a widely-used numerical integration technique. The results of this study revealed that the new, simple analytical models are accurate, fast, and broadly applicable. The new models require just 6 parameters to calculate stopping power and range for a given ion and absorber. The proposed model may be useful as an alternative to traditional approaches, especially in applications that demand fast computation speed, small memory footprint, and simplicity.
NASA Astrophysics Data System (ADS)
Martínez-Casado, R.; Vega, J. L.; Sanz, A. S.; Miret-Artés, S.
2007-08-01
The study of diffusion and low-frequency vibrational motions of particles on metal surfaces is of paramount importance; it provides valuable information on the nature of the adsorbate-substrate and substrate-substrate interactions. In particular, the experimental broadening observed in the diffusive peak with increasing coverage is usually interpreted in terms of a dipole-dipole-like interaction among adsorbates via extensive molecular dynamics calculations within the Langevin framework. Here we present an alternative way to interpret this broadening by means of a purely stochastic description, namely the interacting single-adsorbate approximation, where two noise sources are considered: (1) a Gaussian white noise accounting for the surface friction and temperature, and (2) a white shot noise replacing the interaction potential between adsorbates. Standard Langevin numerical simulations for flat and corrugated surfaces (with a separable potential) illustrate the dynamics of Na atoms on a Cu(100) surface which fit fairly well to the analytical expressions issued from simple models (free particle and anharmonic oscillator) when the Gaussian approximation is assumed. A similar broadening is also expected for the frustrated translational mode peaks.
Experimental characterization of deployable trusses and joints
NASA Technical Reports Server (NTRS)
Ikegami, R.; Church, S. M.; Keinholz, D. A.; Fowler, B. L.
1987-01-01
The structural dynamic properties of trusses are strongly affected by the characteristics of joints connecting the individual beam elements. Joints are particularly significant in that they are often the source of nonlinearities and energy dissipation. While the joints themselves may be physically simple, direct measurement is often necessary to obtain a mathematical description suitable for inclusion in a system model. Force state mapping is a flexible, practical test method for obtaining such a description, particularly when significant nonlinear effects are present. It involves measurement of the relationship, nonlinear or linear, between force transmitted through a joint and the relative displacement and velocity across it. An apparatus and procedure for force state mapping are described. Results are presented from tests of joints used in a lightweight, composite, deployable truss built by the Boeing Aerospace Company. The results from the joint tests are used to develop a model of a full 4-bay truss segment. The truss segment was statically and dynamically tested. The results of the truss tests are presented and compared with the analytical predictions from the model.
Lin, Chen-Yen; Halabi, Susan
2017-01-01
We propose a minimand perturbation method to derive the confidence regions for the regularized estimators for the Cox’s proportional hazards model. Although the regularized estimation procedure produces a more stable point estimate, it remains challenging to provide an interval estimator or an analytic variance estimator for the associated point estimate. Based on the sandwich formula, the current variance estimator provides a simple approximation, but its finite sample performance is not entirely satisfactory. Besides, the sandwich formula can only provide variance estimates for the non-zero coefficients. In this article, we present a generic description for the perturbation method and then introduce a computation algorithm using the adaptive least absolute shrinkage and selection operator (LASSO) penalty. Through simulation studies, we demonstrate that our method can better approximate the limiting distribution of the adaptive LASSO estimator and produces more accurate inference compared with the sandwich formula. The simulation results also indicate the possibility of extending the applications to the adaptive elastic-net penalty. We further demonstrate our method using data from a phase III clinical trial in prostate cancer. PMID:29326496
Lin, Chen-Yen; Halabi, Susan
2017-01-01
We propose a minimand perturbation method to derive the confidence regions for the regularized estimators for the Cox's proportional hazards model. Although the regularized estimation procedure produces a more stable point estimate, it remains challenging to provide an interval estimator or an analytic variance estimator for the associated point estimate. Based on the sandwich formula, the current variance estimator provides a simple approximation, but its finite sample performance is not entirely satisfactory. Besides, the sandwich formula can only provide variance estimates for the non-zero coefficients. In this article, we present a generic description for the perturbation method and then introduce a computation algorithm using the adaptive least absolute shrinkage and selection operator (LASSO) penalty. Through simulation studies, we demonstrate that our method can better approximate the limiting distribution of the adaptive LASSO estimator and produces more accurate inference compared with the sandwich formula. The simulation results also indicate the possibility of extending the applications to the adaptive elastic-net penalty. We further demonstrate our method using data from a phase III clinical trial in prostate cancer.
A simple method for estimating frequency response corrections for eddy covariance systems
W. J. Massman
2000-01-01
A simple analytical formula is developed for estimating the frequency attenuation of eddy covariance fluxes due to sensor response, path-length averaging, sensor separation, signal processing, and flux averaging periods. Although it is an approximation based on flat terrain cospectra, this analytical formula should have broader applicability than just flat-terrain...
Understanding Business Analytics
2015-01-05
analytics have been used in organizations for a variety of reasons for quite some time; ranging from the simple (generating and understanding business analytics...process. understanding business analytics 3 How well these two components are orchestrated will determine the level of success an organization has in
The Argumentative Introduction in Oral Interpretation.
ERIC Educational Resources Information Center
Mills, Daniel; Gaer, David C.
A study examined introductions used in competitive oral interpretation events. A total of 97 introductions (from four oral interpretation events at a nationally recognized Midwestern intercollegiate forensic tournament) were analyzed using four categories: Descriptive, Simple Theme, Descriptive and Simple Theme, and Argumentative Theme. Results…
Survival of mutations arising during invasions
Miller, Judith R
2010-01-01
When a neutral mutation arises in an invading population, it quickly either dies out or ‘surfs’, i.e. it comes to occupy almost all the habitat available at its time of origin. Beneficial mutations can also surf, as can deleterious mutations over finite time spans. We develop descriptive statistical models that quantify the relationship between the probability that a mutation will surf and demographic parameters for a cellular automaton model of surfing. We also provide a simple analytic model that performs well at predicting the probability of surfing for neutral and beneficial mutations in one dimension. The results suggest that factors – possibly including even abiotic factors – that promote invasion success may also increase the probability of surfing and associated adaptive genetic change, conditioned on such success. PMID:25567912
Sum-rule corrections: a route to error cancellations in correlation matrix renormalisation theory
NASA Astrophysics Data System (ADS)
Liu, C.; Liu, J.; Yao, Y. X.; Wang, C. Z.; Ho, K. M.
2017-03-01
We recently proposed the correlation matrix renormalisation (CMR) theory to efficiently and accurately calculate ground state total energy of molecular systems, based on the Gutzwiller variational wavefunction (GWF) to treat the electronic correlation effects. To help reduce numerical complications and better adapt the CMR to infinite lattice systems, we need to further refine the way to minimise the error originated from the approximations in the theory. This conference proceeding reports our recent progress on this key issue, namely, we obtained a simple analytical functional form for the one-electron renormalisation factors, and introduced a novel sum-rule correction for a more accurate description of the intersite electron correlations. Benchmark calculations are performed on a set of molecules to show the reasonable accuracy of the method.
Generation of three-dimensional delaunay meshes from weakly structured and inconsistent data
NASA Astrophysics Data System (ADS)
Garanzha, V. A.; Kudryavtseva, L. N.
2012-03-01
A method is proposed for the generation of three-dimensional tetrahedral meshes from incomplete, weakly structured, and inconsistent data describing a geometric model. The method is based on the construction of a piecewise smooth scalar function defining the body so that its boundary is the zero isosurface of the function. Such implicit description of three-dimensional domains can be defined analytically or can be constructed from a cloud of points, a set of cross sections, or a "soup" of individual vertices, edges, and faces. By applying Boolean operations over domains, simple primitives can be combined with reconstruction results to produce complex geometric models without resorting to specialized software. Sharp edges and conical vertices on the domain boundary are reproduced automatically without using special algorithms. Refs. 42. Figs. 25.
Thermodynamics sheds light on black hole dynamics
NASA Astrophysics Data System (ADS)
Cárdenas, Marcela; Julié, Félix-Louis; Deruelle, Nathalie
2018-06-01
We propose to unify two a priori distinct aspects of black hole physics: their thermodynamics, and their description as point particles, which is an essential starting point in the post-Newtonian approach to their dynamics. We will find that, when reducing a black hole to a point particle endowed with its specific effective mass, one in fact describes a black hole satisfying the first law of thermodynamics, such that its global charges, and hence its entropy, remain constant. This gives a thermodynamical interpretation of its effective mass, thus opening a promising synergy between black hole thermodynamics and the analytical approaches to the two-body problems in gravity theories. To illustrate this relationship, the Einstein-Maxwell-dilaton theory, which contains simple examples of asympotically flat, hairy black hole solutions, will serve as a laboratory.
A two-state hysteresis model from high-dimensional friction
Biswas, Saurabh; Chatterjee, Anindya
2015-01-01
In prior work (Biswas & Chatterjee 2014 Proc. R. Soc. A 470, 20130817 (doi:10.1098/rspa.2013.0817)), we developed a six-state hysteresis model from a high-dimensional frictional system. Here, we use a more intuitively appealing frictional system that resembles one studied earlier by Iwan. The basis functions now have simple analytical description. The number of states required decreases further, from six to the theoretical minimum of two. The number of fitted parameters is reduced by an order of magnitude, to just six. An explicit and faster numerical solution method is developed. Parameter fitting to match different specified hysteresis loops is demonstrated. In summary, a new two-state model of hysteresis is presented that is ready for practical implementation. Essential Matlab code is provided. PMID:26587279
Effective description of domain wall strings
NASA Astrophysics Data System (ADS)
Rodrigues, Davi R.; Abanov, Ar.; Sinova, J.; Everschor-Sitte, K.
2018-04-01
The analysis of domain wall dynamics is often simplified to one-dimensional physics. For domain walls in thin films, more realistic approaches require the description as two-dimensional objects. This includes the study of vortices and curvatures along the domain walls as well as the influence of boundary effects. Here we provide a theory in terms of soft modes that allows us to analytically study the physics of extended domain walls and their stability. By considering irregularly shaped skyrmions as closed domain walls, we analyze their plasticity and compare their dynamics with those of circular skyrmions. Our theory directly provides an analytical description of the excitation modes of magnetic skyrmions, previously accessible only through sophisticated micromagnetic numerical calculations and spectral analysis. These analytical expressions provide the scaling behavior of the different physics on parameters that experiments can test.
WHAEM: PROGRAM DOCUMENTATION FOR THE WELLHEAD ANALYTIC ELEMENT MODEL
The Wellhead Analytic Element Model (WhAEM) demonstrates a new technique for the definition of time-of-travel capture zones in relatively simple geohydrologic settings. he WhAEM package includes an analytic element model that uses superposition of (many) analytic solutions to gen...
Galaxy modelling. II. Multi-wavelength faint counts from a semi-analytic model of galaxy formation
NASA Astrophysics Data System (ADS)
Devriendt, J. E. G.; Guiderdoni, B.
2000-11-01
This paper predicts self-consistent faint galaxy counts from the UV to the submm wavelength range. The stardust spectral energy distributions described in Devriendt et al. \\citeparyear{DGS99} (Paper I) are embedded within the explicit cosmological framework of a simple semi-analytic model of galaxy formation and evolution. We begin with a description of the non-dissipative and dissipative collapses of primordial perturbations, and plug in standard recipes for star formation, stellar evolution and feedback. We also model the absorption of starlight by dust and its re-processing in the IR and submm. We then build a class of models which capture the luminosity budget of the universe through faint galaxy counts and redshift distributions in the whole wavelength range spanned by our spectra. In contrast with a rather stable behaviour in the optical and even in the far-IR, the submm counts are dramatically sensitive to variations in the cosmological parameters and changes in the star formation history. Faint submm counts are more easily accommodated within an open universe with a low value of Omega_0 , or a flat universe with a non-zero cosmological constant. We confirm the suggestion of Guiderdoni et al. \\citeparyear{GHBM98} that matching the current multi-wavelength data requires a population of heavily-extinguished, massive galaxies with large star formation rates ( ~ 500 M_sun yr-1) at intermediate and high redshift (z >= 1.5). Such a population of objects probably is the consequence of an increase of interaction and merging activity at high redshift, but a realistic quantitative description can only be obtained through more detailed modelling of such processes. This study illustrates the implementation of multi-wavelength spectra into a semi-analytic model. In spite of its simplicity, it already provides fair fits of the current data of faint counts, and a physically motivated way of interpolating and extrapolating these data to other wavelengths and fainter flux levels.
Theoretical models for supercritical fluid extraction.
Huang, Zhen; Shi, Xiao-Han; Jiang, Wei-Juan
2012-08-10
For the proper design of supercritical fluid extraction processes, it is essential to have a sound knowledge of the mass transfer mechanism of the extraction process and the appropriate mathematical representation. In this paper, the advances and applications of kinetic models for describing supercritical fluid extraction from various solid matrices have been presented. The theoretical models overviewed here include the hot ball diffusion, broken and intact cell, shrinking core and some relatively simple models. Mathematical representations of these models have been in detail interpreted as well as their assumptions, parameter identifications and application examples. Extraction process of the analyte solute from the solid matrix by means of supercritical fluid includes the dissolution of the analyte from the solid, the analyte diffusion in the matrix and its transport to the bulk supercritical fluid. Mechanisms involved in a mass transfer model are discussed in terms of external mass transfer resistance, internal mass transfer resistance, solute-solid interactions and axial dispersion. The correlations of the external mass transfer coefficient and axial dispersion coefficient with certain dimensionless numbers are also discussed. Among these models, the broken and intact cell model seems to be the most relevant mathematical model as it is able to provide realistic description of the plant material structure for better understanding the mass-transfer kinetics and thus it has been widely employed for modeling supercritical fluid extraction of natural matters. Copyright © 2012 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Pletikapić, Galja; Ivošević DeNardis, Nadica
2017-01-01
Surface analytical methods are applied to examine the environmental status of seawaters. The present overview emphasizes advantages of combining surface analytical methods, applied to a hazardous situation in the Adriatic Sea, such as monitoring of the first aggregation phases of dissolved organic matter in order to potentially predict the massive mucilage formation and testing of oil spill cleanup. Such an approach, based on fast and direct characterization of organic matter and its high-resolution visualization, sets a continuous-scale description of organic matter from micro- to nanometre scales. Electrochemical method of chronoamperometry at the dropping mercury electrode meets the requirements for monitoring purposes due to the simple and fast analysis of a large number of natural seawater samples enabling simultaneous differentiation of organic constituents. In contrast, atomic force microscopy allows direct visualization of biotic and abiotic particles and provides an insight into structural organization of marine organic matter at micro- and nanometre scales. In the future, merging data at different spatial scales, taking into account experimental input on micrometre scale, observations on metre scale and modelling on kilometre scale, will be important for developing sophisticated technological platforms for knowledge transfer, reports and maps applicable for the marine environmental protection and management of the coastal area, especially for tourism, fishery and cruiser trafficking.
NASA Astrophysics Data System (ADS)
Milani, G.; Bertolesi, E.
2017-07-01
A simple quasi analytical holonomic homogenization approach for the non-linear analysis of masonry walls in-plane loaded is presented. The elementary cell (REV) is discretized with 24 triangular elastic constant stress elements (bricks) and non-linear interfaces (mortar). A holonomic behavior with softening is assumed for mortar. It is shown how the mechanical problem in the unit cell is characterized by very few displacement variables and how homogenized stress-strain behavior can be evaluated semi-analytically.
A simple analytical aerodynamic model of Langley Winged-Cone Aerospace Plane concept
NASA Technical Reports Server (NTRS)
Pamadi, Bandu N.
1994-01-01
A simple three DOF analytical aerodynamic model of the Langley Winged-Coned Aerospace Plane concept is presented in a form suitable for simulation, trajectory optimization, and guidance and control studies. The analytical model is especially suitable for methods based on variational calculus. Analytical expressions are presented for lift, drag, and pitching moment coefficients from subsonic to hypersonic Mach numbers and angles of attack up to +/- 20 deg. This analytical model has break points at Mach numbers of 1.0, 1.4, 4.0, and 6.0. Across these Mach number break points, the lift, drag, and pitching moment coefficients are made continuous but their derivatives are not. There are no break points in angle of attack. The effect of control surface deflection is not considered. The present analytical model compares well with the APAS calculations and wind tunnel test data for most angles of attack and Mach numbers.
NASA Astrophysics Data System (ADS)
Bassiouni, Maoya; Higgins, Chad W.; Still, Christopher J.; Good, Stephen P.
2018-06-01
Vegetation controls on soil moisture dynamics are challenging to measure and translate into scale- and site-specific ecohydrological parameters for simple soil water balance models. We hypothesize that empirical probability density functions (pdfs) of relative soil moisture or soil saturation encode sufficient information to determine these ecohydrological parameters. Further, these parameters can be estimated through inverse modeling of the analytical equation for soil saturation pdfs, derived from the commonly used stochastic soil water balance framework. We developed a generalizable Bayesian inference framework to estimate ecohydrological parameters consistent with empirical soil saturation pdfs derived from observations at point, footprint, and satellite scales. We applied the inference method to four sites with different land cover and climate assuming (i) an annual rainfall pattern and (ii) a wet season rainfall pattern with a dry season of negligible rainfall. The Nash-Sutcliffe efficiencies of the analytical model's fit to soil observations ranged from 0.89 to 0.99. The coefficient of variation of posterior parameter distributions ranged from < 1 to 15 %. The parameter identifiability was not significantly improved in the more complex seasonal model; however, small differences in parameter values indicate that the annual model may have absorbed dry season dynamics. Parameter estimates were most constrained for scales and locations at which soil water dynamics are more sensitive to the fitted ecohydrological parameters of interest. In these cases, model inversion converged more slowly but ultimately provided better goodness of fit and lower uncertainty. Results were robust using as few as 100 daily observations randomly sampled from the full records, demonstrating the advantage of analyzing soil saturation pdfs instead of time series to estimate ecohydrological parameters from sparse records. Our work combines modeling and empirical approaches in ecohydrology and provides a simple framework to obtain scale- and site-specific analytical descriptions of soil moisture dynamics consistent with soil moisture observations.
High-temperature ratchets with sawtooth potentials
NASA Astrophysics Data System (ADS)
Rozenbaum, Viktor M.; Shapochkina, Irina V.; Sheu, Sheh-Yi; Yang, Dah-Yen; Lin, Sheng Hsien
2016-11-01
The concept of the effective potential is suggested as an efficient instrument to get a uniform analytical description of stochastic high-temperature on-off flashing and rocking ratchets. The analytical representation for the average particle velocity, obtained within this technique, allows description of ratchets with sharp potentials (and potentials with jumps in particular). For sawtooth potentials, the explicit analytical expressions for the average velocity of on-off flashing and rocking ratchets valid for arbitrary frequencies of potential energy fluctuations are derived; the difference in their high-frequency asymptotics is explored for the smooth and cusped profiles, and profiles with jumps. The origin of the difference as well as the appearance of the jump behavior in ratchet characteristics are interpreted in terms of self-similar universal solutions which give the continuous description of the effect. It is shown how the jump behavior in motor characteristics arises from the competition between the characteristic times of the system.
40 CFR 60.103a - Design, equipment, work practice or operational standards.
Code of Federal Regulations, 2014 CFR
2014-07-01
...) Description and simple process flow diagram showing the interconnection of the following components of the... rate. (iv) Description and simple process flow diagram showing all gas lines (including flare, purge... which lines are monitored and identify on the process flow diagram the location and type of each monitor...
40 CFR 60.103a - Design, equipment, work practice or operational standards.
Code of Federal Regulations, 2013 CFR
2013-07-01
...) Description and simple process flow diagram showing the interconnection of the following components of the... rate. (iv) Description and simple process flow diagram showing all gas lines (including flare, purge... which lines are monitored and identify on the process flow diagram the location and type of each monitor...
Analytical Applications of NMR: Summer Symposium on Analytical Chemistry.
ERIC Educational Resources Information Center
Borman, Stuart A.
1982-01-01
Highlights a symposium on analytical applications of nuclear magnetic resonance spectroscopy (NMR), discussing pulse Fourier transformation technique, two-dimensional NMR, solid state NMR, and multinuclear NMR. Includes description of ORACLE, an NMR data processing system at Syracuse University using real-time color graphics, and algorithms for…
Scaling and efficiency determine the irreversible evolution of a market
Baldovin, F.; Stella, A. L.
2007-01-01
In setting up a stochastic description of the time evolution of a financial index, the challenge consists in devising a model compatible with all stylized facts emerging from the analysis of financial time series and providing a reliable basis for simulating such series. Based on constraints imposed by market efficiency and on an inhomogeneous-time generalization of standard simple scaling, we propose an analytical model which accounts simultaneously for empirical results like the linear decorrelation of successive returns, the power law dependence on time of the volatility autocorrelation function, and the multiscaling associated to this dependence. In addition, our approach gives a justification and a quantitative assessment of the irreversible character of the index dynamics. This irreversibility enters as a key ingredient in a novel simulation strategy of index evolution which demonstrates the predictive potential of the model.
A comparison between numerically modelled and experimentally measured loss mechanisms in wave rotors
NASA Technical Reports Server (NTRS)
Paxson, Daniel E.
1993-01-01
A numerical model has been developed which is capable of predicting the performance of a wave rotor (pressure exchanger) of specified geometry over a wide range of operating conditions. The model can account for the major loss mechanisms of leakage from the tube ends, fluid viscosity, heat transfer to the tube wails, finite tube opening time, shock waves, and non-uniform port flows. It is a one dimensional flow model which follows a single tube as it rotates past the various stationary ports. Since the model is relatively simple (i.e., one dimensional) it uses little computer time. This makes it suitable for design as well as analytical purposes. This paper will present a brief description of the model then discuss a comparison between the model predictions and several wave rotor experiments.
A Comparison Between Numerically Modelled and Experimentally Measured Loss Mechanisms in Wave Rotors
NASA Technical Reports Server (NTRS)
Paxson, Daniel E.
1993-01-01
A numerical model has been developed which is capable of predicting the performance of a wave rotor (pressure exchanger) of specified geometry over a wide range of operating conditions. The model can account for the major loss mechanisms of leakage from the tube ends, fluid viscosity, heat transfer to the tube walls, finite tube opening time, shock waves, and non-uniform port flows. It is a one dimensional flow model which follows a single tube as it rotates past the various stationary ports. Since the model is relatively simple (i.e. one dimensional) it uses little computer time. This makes it suitable for design as well as analytical purposes. This paper will present a brief description of the model then discuss a comparison between the model predictions and several wave rotor experiments.
Sum-rule corrections: A route to error cancellations in correlation matrix renormalisation theory
Liu, C.; Liu, J.; Yao, Y. X.; ...
2017-01-16
Here, we recently proposed the correlation matrix renormalisation (CMR) theory to efficiently and accurately calculate ground state total energy of molecular systems, based on the Gutzwiller variational wavefunction (GWF) to treat the electronic correlation effects. To help reduce numerical complications and better adapt the CMR to infinite lattice systems, we need to further refine the way to minimise the error originated from the approximations in the theory. This conference proceeding reports our recent progress on this key issue, namely, we obtained a simple analytical functional form for the one-electron renormalisation factors, and introduced a novel sum-rule correction for a moremore » accurate description of the intersite electron correlations. Benchmark calculations are performed on a set of molecules to show the reasonable accuracy of the method.« less
Sum-rule corrections: A route to error cancellations in correlation matrix renormalisation theory
DOE Office of Scientific and Technical Information (OSTI.GOV)
Liu, C.; Liu, J.; Yao, Y. X.
Here, we recently proposed the correlation matrix renormalisation (CMR) theory to efficiently and accurately calculate ground state total energy of molecular systems, based on the Gutzwiller variational wavefunction (GWF) to treat the electronic correlation effects. To help reduce numerical complications and better adapt the CMR to infinite lattice systems, we need to further refine the way to minimise the error originated from the approximations in the theory. This conference proceeding reports our recent progress on this key issue, namely, we obtained a simple analytical functional form for the one-electron renormalisation factors, and introduced a novel sum-rule correction for a moremore » accurate description of the intersite electron correlations. Benchmark calculations are performed on a set of molecules to show the reasonable accuracy of the method.« less
Lunar ash flows - Isothermal approximation.
NASA Technical Reports Server (NTRS)
Pai, S. I.; Hsieh, T.; O'Keefe, J. A.
1972-01-01
Suggestion of the ash flow mechanism as one of the major processes required to account for some features of lunar soil. First the observational background and the gardening hypothesis are reviewed, and the shortcomings of the gardening hypothesis are shown. Then a general description of the lunar ash flow is given, and a simple mathematical model of the isothermal lunar ash flow is worked out with numerical examples to show the differences between the lunar and the terrestrial ash flow. The important parameters of the ash flow process are isolated and analyzed. It appears that the lunar surface layer in the maria is not a residual mantle rock (regolith) but a series of ash flows due, at least in part, to great meteorite impacts. The possibility of a volcanic contribution is not excluded. Some further analytic research on lunar ash flows is recommended.
Median of patient results as a tool for assessment of analytical stability.
Jørgensen, Lars Mønster; Hansen, Steen Ingemann; Petersen, Per Hyltoft; Sölétormos, György
2015-06-15
In spite of the well-established external quality assessment and proficiency testing surveys of analytical quality performance in laboratory medicine, a simple tool to monitor the long-term analytical stability as a supplement to the internal control procedures is often needed. Patient data from daily internal control schemes was used for monthly appraisal of the analytical stability. This was accomplished by using the monthly medians of patient results to disclose deviations from analytical stability, and by comparing divergences with the quality specifications for allowable analytical bias based on biological variation. Seventy five percent of the twenty analytes achieved on two COBASs INTEGRA 800 instruments performed in accordance with the optimum and with the desirable specifications for bias. Patient results applied in analytical quality performance control procedures are the most reliable sources of material as they represent the genuine substance of the measurements and therefore circumvent the problems associated with non-commutable materials in external assessment. Patient medians in the monthly monitoring of analytical stability in laboratory medicine are an inexpensive, simple and reliable tool to monitor the steadiness of the analytical practice. Copyright © 2015 Elsevier B.V. All rights reserved.
Analytical Chemistry: A Literary Approach.
ERIC Educational Resources Information Center
Lucy, Charles A.
2000-01-01
Provides an anthology of references to descriptions of analytical chemistry techniques from history, popular fiction, and film which can be used to capture student interest and frame discussions of chemical techniques. (WRM)
Continuum description of solvent dielectrics in molecular-dynamics simulations of proteins
NASA Astrophysics Data System (ADS)
Egwolf, Bernhard; Tavan, Paul
2003-02-01
We present a continuum approach for efficient and accurate calculation of reaction field forces and energies in classical molecular-dynamics (MD) simulations of proteins in water. The derivation proceeds in two steps. First, we reformulate the electrostatics of an arbitrarily shaped molecular system, which contains partially charged atoms and is embedded in a dielectric continuum representing the water. A so-called fuzzy partition is used to exactly decompose the system into partial atomic volumes. The reaction field is expressed by means of dipole densities localized at the atoms. Since these densities cannot be calculated analytically for general systems, we introduce and carefully analyze a set of approximations in a second step. These approximations allow us to represent the dipole densities by simple dipoles localized at the atoms. We derive a system of linear equations for these dipoles, which can be solved numerically by iteration. After determining the two free parameters of our approximate method we check its quality by comparisons (i) with an analytical solution, which is available for a perfectly spherical system, (ii) with forces obtained from a MD simulation of a soluble protein in water, and (iii) with reaction field energies of small molecules calculated by a finite difference method.
To address accuracy and precision using methods from analytical chemistry and computational physics.
Kozmutza, Cornelia; Picó, Yolanda
2009-04-01
In this work the pesticides were determined by liquid chromatography-mass spectrometry (LC-MS). In present study the occurrence of imidacloprid in 343 samples of oranges, tangerines, date plum, and watermelons from Valencian Community (Spain) has been investigated. The nine additional pesticides were chosen as they have been recommended for orchard treatment together with imidacloprid. The Mulliken population analysis has been applied to present the charge distribution in imidacloprid. Partitioned energy terms and the virial ratios have been calculated for certain molecules entering in interaction. A new technique based on the comparison of the decomposed total energy terms at various configurations is demonstrated in this work. The interaction ability could be established correctly in the studied case. An attempt is also made in this work to address accuracy and precision. These quantities are well-known in experimental measurements. In case precise theoretical description is achieved for the contributing monomers and also for the interacting complex structure some properties of this latter system can be predicted to quite a good accuracy. Based on simple hypothetical considerations we estimate the impact of applying computations on reducing the amount of analytical work.
Asymptotic theory of time-varying social networks with heterogeneous activity and tie allocation.
Ubaldi, Enrico; Perra, Nicola; Karsai, Márton; Vezzani, Alessandro; Burioni, Raffaella; Vespignani, Alessandro
2016-10-24
The dynamic of social networks is driven by the interplay between diverse mechanisms that still challenge our theoretical and modelling efforts. Amongst them, two are known to play a central role in shaping the networks evolution, namely the heterogeneous propensity of individuals to i) be socially active and ii) establish a new social relationships with their alters. Here, we empirically characterise these two mechanisms in seven real networks describing temporal human interactions in three different settings: scientific collaborations, Twitter mentions, and mobile phone calls. We find that the individuals' social activity and their strategy in choosing ties where to allocate their social interactions can be quantitatively described and encoded in a simple stochastic network modelling framework. The Master Equation of the model can be solved in the asymptotic limit. The analytical solutions provide an explicit description of both the system dynamic and the dynamical scaling laws characterising crucial aspects about the evolution of the networks. The analytical predictions match with accuracy the empirical observations, thus validating the theoretical approach. Our results provide a rigorous dynamical system framework that can be extended to include other processes shaping social dynamics and to generate data driven predictions for the asymptotic behaviour of social networks.
Asymptotic theory of time-varying social networks with heterogeneous activity and tie allocation
NASA Astrophysics Data System (ADS)
Ubaldi, Enrico; Perra, Nicola; Karsai, Márton; Vezzani, Alessandro; Burioni, Raffaella; Vespignani, Alessandro
2016-10-01
The dynamic of social networks is driven by the interplay between diverse mechanisms that still challenge our theoretical and modelling efforts. Amongst them, two are known to play a central role in shaping the networks evolution, namely the heterogeneous propensity of individuals to i) be socially active and ii) establish a new social relationships with their alters. Here, we empirically characterise these two mechanisms in seven real networks describing temporal human interactions in three different settings: scientific collaborations, Twitter mentions, and mobile phone calls. We find that the individuals’ social activity and their strategy in choosing ties where to allocate their social interactions can be quantitatively described and encoded in a simple stochastic network modelling framework. The Master Equation of the model can be solved in the asymptotic limit. The analytical solutions provide an explicit description of both the system dynamic and the dynamical scaling laws characterising crucial aspects about the evolution of the networks. The analytical predictions match with accuracy the empirical observations, thus validating the theoretical approach. Our results provide a rigorous dynamical system framework that can be extended to include other processes shaping social dynamics and to generate data driven predictions for the asymptotic behaviour of social networks.
NASA Astrophysics Data System (ADS)
Samsing, Johan; Askar, Abbas; Giersz, Mirek
2018-03-01
We estimate the population of eccentric gravitational wave (GW) binary black hole (BBH) mergers forming during binary–single interactions in globular clusters (GCs), using ∼800 GC models that were evolved using the MOCCA code for star cluster simulations as part of the MOCCA-Survey Database I project. By re-simulating BH binary–single interactions extracted from this set of GC models using an N-body code that includes GW emission at the 2.5 post-Newtonian level, we find that ∼10% of all the BBHs assembled in our GC models that merge at present time form during chaotic binary–single interactions, and that about half of this sample have an eccentricity >0.1 at 10 Hz. We explicitly show that this derived rate of eccentric mergers is ∼100 times higher than one would find with a purely Newtonian N-body code. Furthermore, we demonstrate that the eccentric fraction can be accurately estimated using a simple analytical formalism when the interacting BHs are of similar mass, a result that serves as the first successful analytical description of eccentric GW mergers forming during three-body interactions in realistic GCs.
Is Analytic Information Processing a Feature of Expertise in Medicine?
ERIC Educational Resources Information Center
McLaughlin, Kevin; Rikers, Remy M.; Schmidt, Henk G.
2008-01-01
Diagnosing begins by generating an initial diagnostic hypothesis by automatic information processing. Information processing may stop here if the hypothesis is accepted, or analytical processing may be used to refine the hypothesis. This description portrays analytic processing as an optional extra in information processing, leading us to…
A simple, analytical, axisymmetric microburst model for downdraft estimation
NASA Technical Reports Server (NTRS)
Vicroy, Dan D.
1991-01-01
A simple analytical microburst model was developed for use in estimating vertical winds from horizontal wind measurements. It is an axisymmetric, steady state model that uses shaping functions to satisfy the mass continuity equation and simulate boundary layer effects. The model is defined through four model variables: the radius and altitude of the maximum horizontal wind, a shaping function variable, and a scale factor. The model closely agrees with a high fidelity analytical model and measured data, particularily in the radial direction and at lower altitudes. At higher altitudes, the model tends to overestimate the wind magnitude relative to the measured data.
Simple analytical model of a thermal diode
NASA Astrophysics Data System (ADS)
Kaushik, Saurabh; Kaushik, Sachin; Marathe, Rahul
2018-05-01
Recently there is a lot of attention given to manipulation of heat by constructing thermal devices such as thermal diodes, transistors and logic gates. Many of the models proposed have an asymmetry which leads to the desired effect. Presence of non-linear interactions among the particles is also essential. But, such models lack analytical understanding. Here we propose a simple, analytically solvable model of a thermal diode. Our model consists of classical spins in contact with multiple heat baths and constant external magnetic fields. Interestingly the magnetic field is the only parameter required to get the effect of heat rectification.
Type of body fat distribution in postmenopausal women and its related factors.
Noroozi, Mahnaz; Rastegari, Zahra; Paknahad, Zamzam
2010-01-01
The type of body fat distribution has an important role for identifying risk of diseases. One of the simple anthropometric indexes for estimating type of body fat distribution is waist circumference index. This study is aimed to determine the type of body fat distribution in postmenopausal women and its related factors. This is a cross sectional descriptive analytical study. Samples were 278 postmenopausal women in Isfahan who were selected by stratified sampling and then were invited to 64 health centers of Isfahan. Data was gathered using a questionnaire and standard meter. Data was analyzed using SPSS software and descriptive and inferential statistics. Results showed that in postmenopausal women the mean of waist circumference index was 93.63 (10.66) and its range was 54 to 119 cm. There was a meaningful relation between job, educational status, total pregnancies, total deliveries, age of first pregnancy, lactation history and menopausal age with waist circumference index. Results showed that the type of body fat distribution of postmenopausal women is of android type. Considering side effects of this kind of distribution, necessary teachings about healthy eating, movement and exercises must be given to women of these ages.
Failure of Breit-Wigner and success of dispersive descriptions of the τ- → K-ηντ decays
NASA Astrophysics Data System (ADS)
Roig, Pablo
2015-11-01
The τ- → K-ηντ decays have been studied using Chiral Perturbation Theory extended by including resonances as active fields. We have found that the treatment of final state interactions is crucial to provide a good description of the data. The Breit-Wigner approximation does not resum them and neglects the real part of the corresponding chiral loop functions, which violates analyticity and leads to a failure in the confrontation with the data. On the contrary, its resummation by means of an Omnes-like exponentiation of through a dispersive representation provides a successful explanation of the measurements. These results illustrate the fact that Breit-Wigner parametrizations of hadronic data, although simple and easy to handle, lack a link with the underlying strong interaction theory and should be avoided. As a result of our analysis we determine the properties of the K* (1410) resonance with a precision competitive to its traditional extraction using τ- → (Kπ)-ντ decays, albeit the much limited statistics accumulated for the τ- → K-ηντ channel. We also predict the soon discovery of the τ- → K-η'ντ decays.
Learning in Structured Connectionist Networks
1988-04-01
the structure is too rigid and learning too difficult for cognitive modeling. Two algorithms for learning simple, feature-based concept descriptions...and learning too difficult for cognitive model- ing. Two algorithms for learning simple, feature-based concept descriptions were also implemented. The...Term Goals Recent progress in connectionist research has been encouraging; networks have success- fully modeled human performance for various cognitive
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-03
... estimated. The proposed rule will require that State agencies provide descriptive information regarding the... Burden on Respondents Section 272.12(3) requires that States provide both descriptive and analytic... analysis in the normal course of their own planning and decisionmaking. The descriptive information should...
Stochastic oscillations in models of epidemics on a network of cities
NASA Astrophysics Data System (ADS)
Rozhnova, G.; Nunes, A.; McKane, A. J.
2011-11-01
We carry out an analytic investigation of stochastic oscillations in a susceptible-infected-recovered model of disease spread on a network of n cities. In the model a fraction fjk of individuals from city k commute to city j, where they may infect, or be infected by, others. Starting from a continuous-time Markov description of the model the deterministic equations, which are valid in the limit when the population of each city is infinite, are recovered. The stochastic fluctuations about the fixed point of these equations are derived by use of the van Kampen system-size expansion. The fixed point structure of the deterministic equations is remarkably simple: A unique nontrivial fixed point always exists and has the feature that the fraction of susceptible, infected, and recovered individuals is the same for each city irrespective of its size. We find that the stochastic fluctuations have an analogously simple dynamics: All oscillations have a single frequency, equal to that found in the one-city case. We interpret this phenomenon in terms of the properties of the spectrum of the matrix of the linear approximation of the deterministic equations at the fixed point.
NASA Astrophysics Data System (ADS)
Palazzi, E.
The evaluation of atmospheric dispersion of a cloud, arising from a sudden release of flammable or toxic materials, is an essential tool for properly designing flares, vents and other safety devices and to quantify the potential risk related to the existing ones or arising from the various kinds of accidents which can occur in chemical plants. Among the methods developed to treat the important case of upward-directed jets, Hoehne's procedure for determining the behaviour and extent of flammability zone is extensively utilized, particularly concerning petrochemical plants. In a previous study, a substantial simplification of the aforesaid procedure was achieved, by correlating the experimental data with an empirical formula, allowing to obtain a mathematical description of the boundaries of the flammable cloud. Following a theoretical approach, a most general model is developed in the present work, applicable to the various kinds of design problems and/or risk evaluation regarding upward-directed releases from high velocity sources. It is also demonstrated that the model gives conservative results, if applied outside the range of the Hoehne's experimental conditions. Moreover, with simple modifications, the same approach could be easily applied to deal with the atmospheric dispersion of anyhow directed releases.
DEMONSTRATION OF THE ANALYTIC ELEMENT METHOD FOR WELLHEAD PROTECTION
A new computer program has been developed to determine time-of-travel capture zones in relatively simple geohydrological settings. The WhAEM package contains an analytic element model that uses superposition of (many) closed form analytical solutions to generate a ground-water fl...
Analytical Tools in School Finance Reform.
ERIC Educational Resources Information Center
Johns, R. L.
This paper discusses the problem of analyzing variations in the educational opportunities provided by different school districts and describes how to assess the impact of school finance alternatives through use of various analytical tools. The author first examines relatively simple analytical methods, including calculation of per-pupil…
Galy, Bertrand; Lan, André
2018-03-01
Among the many occupational risks construction workers encounter every day falling from a height is the most dangerous. The objective of this article is to propose a simple analytical design method for horizontal lifelines (HLLs) that considers anchorage flexibility. The article presents a short review of the standards and regulations/acts/codes concerning HLLs in Canada the USA and Europe. A static analytical approach is proposed considering anchorage flexibility. The analytical results are compared with a series of 42 dynamic fall tests and a SAP2000 numerical model. The experimental results show that the analytical method is a little conservative and overestimates the line tension in most cases with a maximum of 17%. The static SAP2000 results show a maximum 2.1% difference with the analytical method. The analytical method is accurate enough to safely design HLLs and quick design abaci are provided to allow the engineer to make quick on-site verification if needed.
DEMONSTRATION OF THE ANALYTIC ELEMENT METHOD FOR WELLHEAD PROJECTION - PROJECT SUMMARY
A new computer program has been developed to determine time-of-travel capture zones in relatively simple geohydrological settings. The WhAEM package contains an analytic element model that uses superposition of (many) closed form analytical solutions to generate a ground-water fl...
NASA Technical Reports Server (NTRS)
Liu, F. C.
1986-01-01
The objective of this investigation is to make analytical determination of the acceleration produced by crew motion in an orbiting space station and define design parameters for the suspension system of microgravity experiments. A simple structural model for simulation of the IOC space station is proposed. Mathematical formulation of this model provides the engineers a simple and direct tool for designing an effective suspension system.
An Analytical State Transition Matrix for Orbits Perturbed by an Oblate Spheroid
NASA Technical Reports Server (NTRS)
Mueller, A. C.
1977-01-01
An analytical state transition matrix and its inverse, which include the short period and secular effects of the second zonal harmonic, were developed from the nonsingular PS satellite theory. The fact that the independent variable in the PS theory is not time is in no respect disadvantageous, since any explicit analytical solution must be expressed in the true or eccentric anomaly. This is shown to be the case for the simple conic matrix. The PS theory allows for a concise, accurate, and algorithmically simple state transition matrix. The improvement over the conic matrix ranges from 2 to 4 digits accuracy.
Analytic and heuristic processing influences on adolescent reasoning and decision-making.
Klaczynski, P A
2001-01-01
The normative/descriptive gap is the discrepancy between actual reasoning and traditional standards for reasoning. The relationship between age and the normative/descriptive gap was examined by presenting adolescents with a battery of reasoning and decision-making tasks. Middle adolescents (N = 76) performed closer to normative ideals than early adolescents (N = 66), although the normative/descriptive gap was large for both groups. Correlational analyses revealed that (1) normative responses correlated positively with each other, (2) nonnormative responses were positively interrelated, and (3) normative and nonnormative responses were largely independent. Factor analyses suggested that performance was based on two processing systems. The "analytic" system operates on "decontextualized" task representations and underlies conscious, computational reasoning. The "heuristic" system operates on "contextualized," content-laden representations and produces "cognitively cheap" responses that sometimes conflict with traditional norms. Analytic processing was more clearly linked to age and to intelligence than heuristic processing. Implications for cognitive development, the competence/performance issue, and rationality are discussed.
Description and Recognition of the Concept of Social Capital in Higher Education System
ERIC Educational Resources Information Center
Tonkaboni, Forouzan; Yousefy, Alireza; Keshtiaray, Narges
2013-01-01
The current research is intended to describe and recognize the concept of social capital in higher education based on theoretical method in a descriptive-analytical approach. Description and Recognition of the data, gathered from theoretical and experimental studies, indicated that social capital is one of the most important indices for…
Structured Natural-Language Descriptions for Semantic Content Retrieval of Visual Materials.
ERIC Educational Resources Information Center
Tam, A. M.; Leung, C. H. C.
2001-01-01
Proposes a structure for natural language descriptions of the semantic content of visual materials that requires descriptions to be (modified) keywords, phrases, or simple sentences, with components that are grammatical relations common to many languages. This structure makes it easy to implement a collection's descriptions as a relational…
WHAEM: PROGRAM DOCUMENTATION FOR THE WELLHEAD ANALYTIC ELEMENT MODEL (EPA/600/SR-94/210)
A new computer program has been developed to determine time-of-travel capture zones in relatively simple geohydrological settings. The WhAEM package contains an analytic element model that uses superposition of (many) closed form analytical solutions to generate a groundwater flo...
Proxy-SU(3) symmetry in heavy deformed nuclei
NASA Astrophysics Data System (ADS)
Bonatsos, Dennis; Assimakis, I. E.; Minkov, N.; Martinou, Andriana; Cakirli, R. B.; Casten, R. F.; Blaum, K.
2017-06-01
Background: Microscopic calculations of heavy nuclei face considerable difficulties due to the sizes of the matrices that need to be solved. Various approximation schemes have been invoked, for example by truncating the spaces, imposing seniority limits, or appealing to various symmetry schemes such as pseudo-SU(3). This paper proposes a new symmetry scheme also based on SU(3). This proxy-SU(3) can be applied to well-deformed nuclei, is simple to use, and can yield analytic predictions. Purpose: To present the new scheme and its microscopic motivation, and to test it using a Nilsson model calculation with the original shell model orbits and with the new proxy set. Method: We invoke an approximate, analytic, treatment of the Nilsson model, that allows the above vetting and yet is also transparent in understanding the approximations involved in the new proxy-SU(3). Results: It is found that the new scheme yields a Nilsson diagram for well-deformed nuclei that is very close to the original Nilsson diagram. The specific levels of approximation in the new scheme are also shown, for each major shell. Conclusions: The new proxy-SU(3) scheme is a good approximation to the full set of orbits in a major shell. Being able to replace a complex shell model calculation with a symmetry-based description now opens up the possibility to predict many properties of nuclei analytically and often in a parameter-free way. The new scheme works best for heavier nuclei, precisely where full microscopic calculations are most challenged. Some cases in which the new scheme can be used, often analytically, to make specific predictions, are shown in a subsequent paper.
Computationally efficient thermal-mechanical modelling of selective laser melting
NASA Astrophysics Data System (ADS)
Yang, Yabin; Ayas, Can
2017-10-01
The Selective laser melting (SLM) is a powder based additive manufacturing (AM) method to produce high density metal parts with complex topology. However, part distortions and accompanying residual stresses deteriorates the mechanical reliability of SLM products. Modelling of the SLM process is anticipated to be instrumental for understanding and predicting the development of residual stress field during the build process. However, SLM process modelling requires determination of the heat transients within the part being built which is coupled to a mechanical boundary value problem to calculate displacement and residual stress fields. Thermal models associated with SLM are typically complex and computationally demanding. In this paper, we present a simple semi-analytical thermal-mechanical model, developed for SLM that represents the effect of laser scanning vectors with line heat sources. The temperature field within the part being build is attained by superposition of temperature field associated with line heat sources in a semi-infinite medium and a complimentary temperature field which accounts for the actual boundary conditions. An analytical solution of a line heat source in a semi-infinite medium is first described followed by the numerical procedure used for finding the complimentary temperature field. This analytical description of the line heat sources is able to capture the steep temperature gradients in the vicinity of the laser spot which is typically tens of micrometers. In turn, semi-analytical thermal model allows for having a relatively coarse discretisation of the complimentary temperature field. The temperature history determined is used to calculate the thermal strain induced on the SLM part. Finally, a mechanical model governed by elastic-plastic constitutive rule having isotropic hardening is used to predict the residual stresses.
Semiotics and semiology of Nursing: evaluation of undergraduate students' knowledge on procedures.
Melo, Gabriela de Sousa Martins; Tibúrcio, Manuela Pinto; Freitas, Camylla Cavalcante Soares de; Vasconcelos, Quinídia Lúcia Duarte de Almeida Quithé de; Costa, Isabel Karolyne Fernandes; Torres, Gilson de Vasconcelos
2017-04-01
to assess the knowledge of scholars on Nursing regarding simple hands hygiene (SHH), blood pressure measurement (BP), peripheral venipuncture (PV) with venous catheter and male urethral catheterization delay (UCD) procedures. quantitative study carried out between February and May 2014, with 186 undergraduate Nursing students from 5th to 9th period of a public university of Rio Grande do Norte, with application of four questionnaires. One carried out descriptive and analytic analysis. the students presented low average percentage of right answers, especially in blood pressure measurement (55.5%); SHH's average was higher than 70%. The average of correct answers was the highest in SHH (8.6), followed by UCD (7.8), PV (7.4) and BP (6.7). The questions regarding the topic "concepts" showed less correct answers when comparing it to the topic "technique steps". it is necessary to establish knowledge monitoring strategies, in order to stimulate the constant improvement.
Embedding dynamical networks into distributed models
NASA Astrophysics Data System (ADS)
Innocenti, Giacomo; Paoletti, Paolo
2015-07-01
Large networks of interacting dynamical systems are well-known for the complex behaviours they are able to display, even when each node features a quite simple dynamics. Despite examples of such networks being widespread both in nature and in technological applications, the interplay between the local and the macroscopic behaviour, through the interconnection topology, is still not completely understood. Moreover, traditional analytical methods for dynamical response analysis fail because of the intrinsically large dimension of the phase space of the network which makes the general problem intractable. Therefore, in this paper we develop an approach aiming to condense all the information in a compact description based on partial differential equations. By focusing on propagative phenomena, rigorous conditions under which the original network dynamical properties can be successfully analysed within the proposed framework are derived as well. A network of Fitzhugh-Nagumo systems is finally used to illustrate the effectiveness of the proposed method.
Aggregation and folding phase transitions of RNA molecules
NASA Astrophysics Data System (ADS)
Bundschuh, Ralf
2007-03-01
RNA is a biomolecule that is involved in nearly all aspects of cellular functions. In order to perform many of these functions, RNA molecules have to fold into specific secondary structures. This folding is driven by the tendency of the bases to form Watson-Crick base pairs. Beyond the biological importance of RNA, the relatively simple rules for structure formation of RNA make it a very interesting system from the statistical physics point of view. We will present examples of phase transitions in RNA secondary structure formation that are amenable to analytical descriptions. A special focus will be on aggregation between several RNA molecules which is important for some regulatory circuits based on RNA structure, triplet repeat diseases like Huntington's, and as a model for prion diseases. We show that depending on the relative strength of the intramolecular and the intermolecular base pairing, RNA molecules undergo a transition into an aggregated phase and quantitatively characterize this transition.
Membrane-less variable focus liquid lens with manual actuation
NASA Astrophysics Data System (ADS)
Patra, Roshan; Agarwal, Shivam; Kondaraju, Sasidhar; Bahga, Supreet Singh
2017-04-01
We present a tunable, membrane-less, mechanical-wetting liquid lens that can be actuated manually using a linear actuator such as screw or piston. The operation of the liquid lens is based on deforming the interface separating two immiscible liquids with different refractive indices, while pinning the three-phase contact line at the sharp edge of lens aperture. Our lens design improves upon the existing designs of mechanical-wetting lenses by eliminating the use of complex actuation mechanisms, without compromising on the optical performance. We demonstrate the operation of the liquid lens by tuning its power back and forth from negative to positive by simple rotation of a screw. We also present an analytical description of the focal length of the lens and validate it with detailed experimental measurements. Our experiments show that the focal length of the liquid lens can be tuned repeatably without any adverse effects of hysteresis and gravity.
Mechanical model of giant photoexpansion in a chalcogenide glass and the role of photofluidity
NASA Astrophysics Data System (ADS)
Buisson, Manuel; Gueguen, Yann; Laniel, Romain; Cantoni, Christopher; Houizot, Patrick; Bureau, Bruno; Sangleboeuf, Jean-Christophe; Lucas, Pierre
2017-07-01
An analytical model is developed to describe the phenomenon of giant photoexpansion in chalcogenide glasses. The proposed micro-mechanical model is based on the description of photoexpansion as a new type of eigenstrain, i.e. a deformation analogous to thermal expansion induced without external forces. In this framework, it is the viscoelastic flow induced by photofluidity which enable the conversion of the self-equilibrated stress into giant photoexpansion. This simple approach yields good fits to experimental data and demonstrates, for the first time, that the photoinduced viscous flow actually enhances the giant photoexpansion or the giant photocontraction as it has been suggested in the literature. Moreover, it highlights that the shear relaxation time due to photofluidity controls the expansion kinetic. This model is the first step towards describing giant photoexpansion from the point of view of mechanics and it provides the framework for investigating this phenomenon via numerical simulations.
Analytic model for a weakly dissipative shallow-water undular bore.
El, G A; Grimshaw, R H J; Kamchatnov, A M
2005-09-01
We use the integrable Kaup-Boussinesq shallow water system, modified by a small viscous term, to model the formation of an undular bore with a steady profile. The description is made in terms of the corresponding integrable Whitham system, also appropriately modified by viscosity. This is derived in Riemann variables using a modified finite-gap integration technique for the Ablowitz-Kaup-Newell-Segur (AKNS) scheme. The Whitham system is then reduced to a simple first-order differential equation which is integrated numerically to obtain an asymptotic profile of the undular bore, with the local oscillatory structure described by the periodic solution of the unperturbed Kaup-Boussinesq system. This solution of the Whitham equations is shown to be consistent with certain jump conditions following directly from conservation laws for the original system. A comparison is made with the recently studied dissipationless case for the same system, where the undular bore is unsteady.
A charge-based model of Junction Barrier Schottky rectifiers
NASA Astrophysics Data System (ADS)
Latorre-Rey, Alvaro D.; Mudholkar, Mihir; Quddus, Mohammed T.; Salih, Ali
2018-06-01
A new charge-based model of the electric field distribution for Junction Barrier Schottky (JBS) diodes is presented, based on the description of the charge-sharing effect between the vertical Schottky junction and the lateral pn-junctions that constitute the active cell of the device. In our model, the inherently 2-D problem is transformed into a simple but accurate 1-D problem which has a closed analytical solution that captures the reshaping and reduction of the electric field profile responsible for the improved electrical performance of these devices, while preserving physically meaningful expressions that depend on relevant device parameters. The validation of the model is performed by comparing calculated electric field profiles with drift-diffusion simulations of a JBS device showing good agreement. Even though other fully 2-D models already available provide higher accuracy, they lack physical insight making the proposed model an useful tool for device design.
Schenk, Emily R; Nau, Frederic; Fernandez-Lima, Francisco
2015-06-01
The ability to correlate experimental ion mobility data with candidate structures from theoretical modeling provides a powerful analytical and structural tool for the characterization of biomolecules. In the present paper, a theoretical workflow is described to generate and assign candidate structures for experimental trapped ion mobility and H/D exchange (HDX-TIMS-MS) data following molecular dynamics simulations and statistical filtering. The applicability of the theoretical predictor is illustrated for a peptide and protein example with multiple conformations and kinetic intermediates. The described methodology yields a low computational cost and a simple workflow by incorporating statistical filtering and molecular dynamics simulations. The workflow can be adapted to different IMS scenarios and CCS calculators for a more accurate description of the IMS experimental conditions. For the case of the HDX-TIMS-MS experiments, molecular dynamics in the "TIMS box" accounts for a better sampling of the molecular intermediates and local energy minima.
Numerical Modeling of Ablation Heat Transfer
NASA Technical Reports Server (NTRS)
Ewing, Mark E.; Laker, Travis S.; Walker, David T.
2013-01-01
A unique numerical method has been developed for solving one-dimensional ablation heat transfer problems. This paper provides a comprehensive description of the method, along with detailed derivations of the governing equations. This methodology supports solutions for traditional ablation modeling including such effects as heat transfer, material decomposition, pyrolysis gas permeation and heat exchange, and thermochemical surface erosion. The numerical scheme utilizes a control-volume approach with a variable grid to account for surface movement. This method directly supports implementation of nontraditional models such as material swelling and mechanical erosion, extending capabilities for modeling complex ablation phenomena. Verifications of the numerical implementation are provided using analytical solutions, code comparisons, and the method of manufactured solutions. These verifications are used to demonstrate solution accuracy and proper error convergence rates. A simple demonstration of a mechanical erosion (spallation) model is also provided to illustrate the unique capabilities of the method.
Analytical Description of Ascending Motion of Rockets in the Atmosphere
ERIC Educational Resources Information Center
Rodrigues, H.; de Pinho, M. O.; Portes, D., Jr.; Santiago, A.
2009-01-01
In continuation of a previous work, we present an analytic study of ascending vertical motion of a rocket subjected to a quadratic drag for the case where the mass-variation law is a linear function of time. We discuss the detailed analytical solution of the model differential equations in closed form. Examples of application are presented and…
Forest landscape description and inventories - a basis for landplanning and design
R. Burton Litton
1968-01-01
Describes six analytical factors and seven compositional types useful in recognition and description of scenic resources. Illustrates their application in two inventories made to aid managers and landscape architects in planning and design.
Consistent Yokoya-Chen Approximation to Beamstrahlung(LCC-0010)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Peskin, M
2004-04-22
I reconsider the Yokoya-Chen approximate evolution equation for beamstrahlung and modify it slightly to generate simple, consistent analytical approximations for the electron and photon energy spectra. I compare these approximations to previous ones, and to simulation data.I reconsider the Yokoya-Chen approximate evolution equation for beamstrahlung and modify it slightly to generate simple, consistent analytical approximations for the electron and photon energy spectra. I compare these approximations to previous ones, and to simulation data.
FAST COGNITIVE AND TASK ORIENTED, ITERATIVE DATA DISPLAY (FACTOID)
2017-06-01
approaches. As a result, the following assumptions guided our efforts in developing modeling and descriptive metrics for evaluation purposes...Application Evaluation . Our analytic workflow for evaluation is to first provide descriptive statistics about applications across metrics (performance...distributions for evaluation purposes because the goal of evaluation is accurate description , not inference (e.g., prediction). Outliers depicted
Tracy, J I; Pinsk, M; Helverson, J; Urban, G; Dietz, T; Smith, D J
2001-08-01
The link between automatic and effortful processing and nonanalytic and analytic category learning was evaluated in a sample of 29 college undergraduates using declarative memory, semantic category search, and pseudoword categorization tasks. Automatic and effortful processing measures were hypothesized to be associated with nonanalytic and analytic categorization, respectively. Results suggested that contrary to prediction strong criterion-attribute (analytic) responding on the pseudoword categorization task was associated with strong automatic, implicit memory encoding of frequency-of-occurrence information. Data are discussed in terms of the possibility that criterion-attribute category knowledge, once established, may be expressed with few attentional resources. The data indicate that attention resource requirements, even for the same stimuli and task, vary depending on the category rule system utilized. Also, the automaticity emerging from familiarity with analytic category exemplars is very different from the automaticity arising from extensive practice on a semantic category search task. The data do not support any simple mapping of analytic and nonanalytic forms of category learning onto the automatic and effortful processing dichotomy and challenge simple models of brain asymmetries for such procedures. Copyright 2001 Academic Press.
NASA Astrophysics Data System (ADS)
Toropova, L. V.; Alexandrov, D. V.
2018-05-01
The directional solidification of a ternary system with an extended phase transition region is theoretically studied. A mathematical model is developed to describe quasi-stationary solidification, and its analytical solution is constructed with allowance for a nonlinear liquids line equation. We demonstrate that the phase diagram nonlinearity leads to substantial changes of analytical solutions.
Geoscience Australia Publishes Sample Descriptions using W3C standards
NASA Astrophysics Data System (ADS)
Car, N. J.; Cox, S. J. D.; Bastrakova, I.; Wyborn, L. A.
2017-12-01
The recent revision of the W3C Semantic Sensor Network Ontology (SSN) has focused on three key concerns: Extending the scope of the ontology to include sampling and actuation as well as observation and sensing Modularizing the ontology into a simple core with few classes and properties and little formal axiomatization, supplemented by additional modules that formalize the semantics and extend the scope Alignments with several existing applications and upper ontologies These enhancements mean that SSN can now be used as the basis for publishing descriptions of geologic samples as Linked Data. Geoscience Australia maintains a database of about three million samples, collected over 50 years through projects from ocean core, terrestrial rock and hydrochemistry borehole projects, almost all of which are held in in the special-purpose GA samples repository. Access to descriptions of these samples as Linked Data has recently been enabled. The sample descriptions can be viewed in various machine-readable formalizations, including IGSN (XML & RDF), Dublin Core (XML & RDF) and SSN (RDF), as well as web landing-pages for people. Of particular importance is the support for encoding relationships between samples, and between samples and surveys, boreholes, and traverses which they are related to, as well as between samples processed for analytical purposes and their parents, siblings, and back to the original field samples. The SSN extension for Sample Relationships provides an extensible, semantically rich mechanism to capture any relationship necessary to explain the provenance of observation results obtained from samples. Sample citation is facilitated through the use of URI-based persistent identifiers which resolve to samples' landing pages. The sample system also allows PROV pingbacks to be received for samples when users of them record provenance for their actions.
The Role of Nanoparticle Design in Determining Analytical Performance of Lateral Flow Immunoassays.
Zhan, Li; Guo, Shuang-Zhuang; Song, Fayi; Gong, Yan; Xu, Feng; Boulware, David R; McAlpine, Michael C; Chan, Warren C W; Bischof, John C
2017-12-13
Rapid, simple, and cost-effective diagnostics are needed to improve healthcare at the point of care (POC). However, the most widely used POC diagnostic, the lateral flow immunoassay (LFA), is ∼1000-times less sensitive and has a smaller analytical range than laboratory tests, requiring a confirmatory test to establish truly negative results. Here, a rational and systematic strategy is used to design the LFA contrast label (i.e., gold nanoparticles) to improve the analytical sensitivity, analytical detection range, and antigen quantification of LFAs. Specifically, we discovered that the size (30, 60, or 100 nm) of the gold nanoparticles is a main contributor to the LFA analytical performance through both the degree of receptor interaction and the ultimate visual or thermal contrast signals. Using the optimal LFA design, we demonstrated the ability to improve the analytical sensitivity by 256-fold and expand the analytical detection range from 3 log 10 to 6 log 10 for diagnosing patients with inflammatory conditions by measuring C-reactive protein. This work demonstrates that, with appropriate design of the contrast label, a simple and commonly used diagnostic technology can compete with more expensive state-of-the-art laboratory tests.
Tungsten devices in analytical atomic spectrometry
NASA Astrophysics Data System (ADS)
Hou, Xiandeng; Jones, Bradley T.
2002-04-01
Tungsten devices have been employed in analytical atomic spectrometry for approximately 30 years. Most of these atomizers can be electrically heated up to 3000 °C at very high heating rates, with a simple power supply. Usually, a tungsten device is employed in one of two modes: as an electrothermal atomizer with which the sample vapor is probed directly, or as an electrothermal vaporizer, which produces a sample aerosol that is then carried to a separate atomizer for analysis. Tungsten devices may take various physical shapes: tubes, cups, boats, ribbons, wires, filaments, coils and loops. Most of these orientations have been applied to many analytical techniques, such as atomic absorption spectrometry, atomic emission spectrometry, atomic fluorescence spectrometry, laser excited atomic fluorescence spectrometry, metastable transfer emission spectroscopy, inductively coupled plasma optical emission spectrometry, inductively coupled plasma mass spectrometry and microwave plasma atomic spectrometry. The analytical figures of merit and the practical applications reported for these techniques are reviewed. Atomization mechanisms reported for tungsten atomizers are also briefly summarized. In addition, less common applications of tungsten devices are discussed, including analyte preconcentration by adsorption or electrodeposition and electrothermal separation of analytes prior to analysis. Tungsten atomization devices continue to provide simple, versatile alternatives for analytical atomic spectrometry.
Forgetfulness can help you win games.
Burridge, James; Gao, Yu; Mao, Yong
2015-09-01
We present a simple game model where agents with different memory lengths compete for finite resources. We show by simulation and analytically that an instability exists at a critical memory length, and as a result, different memory lengths can compete and coexist in a dynamical equilibrium. Our analytical formulation makes a connection to statistical urn models, and we show that temperature is mirrored by the agent's memory. Our simple model of memory may be incorporated into other game models with implications that we briefly discuss.
Simple functionalization method for single conical pores with a polydopamine layer
NASA Astrophysics Data System (ADS)
Horiguchi, Yukichi; Goda, Tatsuro; Miyahara, Yuji
2018-04-01
Resistive pulse sensing (RPS) is an interesting analytical system in which micro- to nanosized pores are used to evaluate particles or small analytes. Recently, molecular immobilization techniques to improve the performance of RPS have been reported. The problem in functionalization for RPS is that molecular immobilization by chemical reaction is restricted by the pore material type. Herein, a simple functionalization is performed using mussel-inspired polydopamine as an intermediate layer to connect the pore material with functional molecules.
Synthesis of Feedback Controller for Chaotic Systems by Means of Evolutionary Techniques
NASA Astrophysics Data System (ADS)
Senkerik, Roman; Oplatkova, Zuzana; Zelinka, Ivan; Davendra, Donald; Jasek, Roman
2011-06-01
This research deals with a synthesis of control law for three selected discrete chaotic systems by means of analytic programming. The novality of the approach is that a tool for symbolic regression—analytic programming—is used for such kind of difficult problem. The paper consists of the descriptions of analytic programming as well as chaotic systems and used cost function. For experimentation, Self-Organizing Migrating Algorithm (SOMA) with analytic programming was used.
User's guide to the Radiometric Age Data Bank (RADB)
Zartman, Robert Eugene; Cole, James C.; Marvin, Richard F.
1976-01-01
The Radiometric Age Data Bank (RADB) has been established by the U.S. Geological Survey, as a means for collecting and organizing the estimated 100,000 radiometric ages presently published for the United States. RADB has been constructed such that a complete sample description (location, rock type, etc.), literature citation, and extensive analytical data are linked to form an independent record for each sample reported in a published work. Analytical data pertinent to the potassium-argon, rubidium-strontium, uranium-thorium-lead, lead-alpha, and fission-track methods can be accommodated, singly or in combinations, for each record. Data processing is achieved using the GIPSY program (University of Oklahoma) which maintains the data file and builds, updates, searches, and prints the records using simple yet versatile command statements. Searching and selecting records is accomplished by specifying the presence, absence, or (numeric or alphabetic) value of any element of information in the data bank, and these specifications can be logically linked to develop sophisticated searching strategies. Output is available in the form of complete data records, abbreviated tests, or columnar tabulations. Samples of data-reporting forms, GIPSY command statements, output formats, and data records are presented to illustrate the comprehensive nature and versatility of the Radiometric Age Data Bank.
On the theory of drainage area for regular and non-regular points.
Bonetti, S; Bragg, A D; Porporato, A
2018-03-01
The drainage area is an important, non-local property of a landscape, which controls surface and subsurface hydrological fluxes. Its role in numerous ecohydrological and geomorphological applications has given rise to several numerical methods for its computation. However, its theoretical analysis has lagged behind. Only recently, an analytical definition for the specific catchment area was proposed (Gallant & Hutchinson. 2011 Water Resour. Res. 47 , W05535. (doi:10.1029/2009WR008540)), with the derivation of a differential equation whose validity is limited to regular points of the watershed. Here, we show that such a differential equation can be derived from a continuity equation (Chen et al. 2014 Geomorphology 219 , 68-86. (doi:10.1016/j.geomorph.2014.04.037)) and extend the theory to critical and singular points both by applying Gauss's theorem and by means of a dynamical systems approach to define basins of attraction of local surface minima. Simple analytical examples as well as applications to more complex topographic surfaces are examined. The theoretical description of topographic features and properties, such as the drainage area, channel lines and watershed divides, can be broadly adopted to develop and test the numerical algorithms currently used in digital terrain analysis for the computation of the drainage area, as well as for the theoretical analysis of landscape evolution and stability.
On the theory of drainage area for regular and non-regular points
NASA Astrophysics Data System (ADS)
Bonetti, S.; Bragg, A. D.; Porporato, A.
2018-03-01
The drainage area is an important, non-local property of a landscape, which controls surface and subsurface hydrological fluxes. Its role in numerous ecohydrological and geomorphological applications has given rise to several numerical methods for its computation. However, its theoretical analysis has lagged behind. Only recently, an analytical definition for the specific catchment area was proposed (Gallant & Hutchinson. 2011 Water Resour. Res. 47, W05535. (doi:10.1029/2009WR008540)), with the derivation of a differential equation whose validity is limited to regular points of the watershed. Here, we show that such a differential equation can be derived from a continuity equation (Chen et al. 2014 Geomorphology 219, 68-86. (doi:10.1016/j.geomorph.2014.04.037)) and extend the theory to critical and singular points both by applying Gauss's theorem and by means of a dynamical systems approach to define basins of attraction of local surface minima. Simple analytical examples as well as applications to more complex topographic surfaces are examined. The theoretical description of topographic features and properties, such as the drainage area, channel lines and watershed divides, can be broadly adopted to develop and test the numerical algorithms currently used in digital terrain analysis for the computation of the drainage area, as well as for the theoretical analysis of landscape evolution and stability.
Targeted Analyte Detection by Standard Addition Improves Detection Limits in MALDI Mass Spectrometry
Eshghi, Shadi Toghi; Li, Xingde; Zhang, Hui
2014-01-01
Matrix-assisted laser desorption/ionization has proven an effective tool for fast and accurate determination of many molecules. However, the detector sensitivity and chemical noise compromise the detection of many invaluable low-abundance molecules from biological and clinical samples. To challenge this limitation, we developed a targeted analyte detection (TAD) technique. In TAD, the target analyte is selectively elevated by spiking a known amount of that analyte into the sample, thereby raising its concentration above the noise level, where we take advantage of the improved sensitivity to detect the presence of the endogenous analyte in the sample. We assessed TAD on three peptides in simple and complex background solutions with various exogenous analyte concentrations in two MALDI matrices. TAD successfully improved the limit of detection (LOD) of target analytes when the target peptides were added to the sample in a concentration close to optimum concentration. The optimum exogenous concentration was estimated through a quantitative method to be approximately equal to the original LOD for each target. Also, we showed that TAD could achieve LOD improvements on an average of 3-fold in a simple and 2-fold in a complex sample. TAD provides a straightforward assay to improve the LOD of generic target analytes without the need for costly hardware modifications. PMID:22877355
Toghi Eshghi, Shadi; Li, Xingde; Zhang, Hui
2012-09-18
Matrix-assisted laser desorption/ionization (MALDI) has proven an effective tool for fast and accurate determination of many molecules. However, the detector sensitivity and chemical noise compromise the detection of many invaluable low-abundance molecules from biological and clinical samples. To challenge this limitation, we developed a targeted analyte detection (TAD) technique. In TAD, the target analyte is selectively elevated by spiking a known amount of that analyte into the sample, thereby raising its concentration above the noise level, where we take advantage of the improved sensitivity to detect the presence of the endogenous analyte in the sample. We assessed TAD on three peptides in simple and complex background solutions with various exogenous analyte concentrations in two MALDI matrices. TAD successfully improved the limit of detection (LOD) of target analytes when the target peptides were added to the sample in a concentration close to optimum concentration. The optimum exogenous concentration was estimated through a quantitative method to be approximately equal to the original LOD for each target. Also, we showed that TAD could achieve LOD improvements on an average of 3-fold in a simple and 2-fold in a complex sample. TAD provides a straightforward assay to improve the LOD of generic target analytes without the need for costly hardware modifications.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Crull, E W; Brown Jr., C G; Perkins, M P
2008-07-30
For short monopoles in this low-power case, it has been shown that a simple circuit model is capable of accurate predictions for the shape and magnitude of the antenna response to lightning-generated electric field coupling effects, provided that the elements of the circuit model have accurate values. Numerical EM simulation can be used to provide more accurate values for the circuit elements than the simple analytical formulas, since the analytical formulas are used outside of their region of validity. However, even with the approximate analytical formulas the simple circuit model produces reasonable results, which would improve if more accurate analyticalmore » models were used. This report discusses the coupling analysis approaches taken to understand the interaction between a time-varying EM field and a short monopole antenna, within the context of lightning safety for nuclear weapons at DOE facilities. It describes the validation of a simple circuit model using laboratory study in order to understand the indirect coupling of energy into a part, and the resulting voltage. Results show that in this low-power case, the circuit model predicts peak voltages within approximately 32% using circuit component values obtained from analytical formulas and about 13% using circuit component values obtained from numerical EM simulation. We note that the analytical formulas are used outside of their region of validity. First, the antenna is insulated and not a bare wire and there are perhaps fringing field effects near the termination of the outer conductor that the formula does not take into account. Also, the effective height formula is for a monopole directly over a ground plane, while in the time-domain measurement setup the monopole is elevated above the ground plane by about 1.5-inch (refer to Figure 5).« less
ERIC Educational Resources Information Center
Behn, Robert D.; Vaupel, James W.
1976-01-01
Description of the philosophy and general nature of a course at Drake University that emphasizes basic concepts of analytical thinking, including think, decompose, simplify, specify, and rethink problems. Some sample homework exercises are included. The journal is available from University of California Press, Berkeley, California 94720.…
Selection of Wavelengths for Optimum Precision in Simultaneous Spectrophotometric Determinations.
ERIC Educational Resources Information Center
DiTusa, Michael R.; Schilt, Alfred A.
1985-01-01
Although many textbooks include a description of simultaneous determinations employing absorption spectrophotometry and treat the mathematics necessary for analytical quantitations, treatment of analytical wavelength selection has been mostly qualitative. Therefore, a general method for selecting wavelengths for optimum precision in simultaneous…
[Developments in preparation and experimental method of solid phase microextraction fibers].
Yi, Xu; Fu, Yujie
2004-09-01
Solid phase microextraction (SPME) is a simple and effective adsorption and desorption technique, which concentrates volatile or nonvolatile compounds from liquid samples or headspace of samples. SPME is compatible with analyte separation and detection by gas chromatography, high performance liquid chromatography, and other instrumental methods. It can provide many advantages, such as wide linear scale, low solvent and sample consumption, short analytical times, low detection limits, simple apparatus, and so on. The theory of SPME is introduced, which includes equilibrium theory and non-equilibrium theory. The novel development of fiber preparation methods and relative experimental techniques are discussed. In addition to commercial fiber preparation, different newly developed fabrication techniques, such as sol-gel, electronic deposition, carbon-base adsorption, high-temperature epoxy immobilization, are presented. Effects of extraction modes, selection of fiber coating, optimization of operating conditions, method sensitivity and precision, and systematical automation, are taken into considerations in the analytical process of SPME. A simple perspective of SPME is proposed at last.
Nurses’ commitment to respecting patient dignity
Raee, Zahra; Abedi, Heidarali; Shahriari, Mohsen
2017-01-01
Background: Although respecting human dignity is a cornerstone of all nursing practices, industrialization has gradually decreased the attention paid to this subject in nursing care. Therefore, the present study aimed to investigate nurses’ commitment to respecting patient dignity in hospitals of Isfahan, Iran. Methods: This descriptive-analytical study was conducted in hospitals of Isfahan. Overall, 401 inpatients were selected by cluster sampling and then selected simple random sampling from different wards. Data were collected through a questionnaire containing the components of patient dignity, that is, patient-nurse relationships, privacy, and independence. All items were scored based on a five-point Likert scale. The collected data were analyzed using descriptive statistics and Chi-square tests. P < 0.05 were considered significant in all analyses. Findings: Most patients (91%) scored their relationships with nurses as good. Moreover, 91.8% of the participants described privacy protection as moderate/good. Only 6.5% of the subjects rated it as excellent. The majority of the patients (84.4%) believed their independence was maintained. These subjects also approved of taking part in decision-making. Conclusion: According to our findings, nurses respected patient dignity to an acceptable level. However, the conditions were less favorable in public hospitals and emergency departments. Nursing authorities and policy makers are thus required to introduce appropriate measures to improve the existing conditions. PMID:28546981
Nurses' commitment to respecting patient dignity.
Raee, Zahra; Abedi, Heidarali; Shahriari, Mohsen
2017-01-01
Although respecting human dignity is a cornerstone of all nursing practices, industrialization has gradually decreased the attention paid to this subject in nursing care. Therefore, the present study aimed to investigate nurses' commitment to respecting patient dignity in hospitals of Isfahan, Iran. This descriptive-analytical study was conducted in hospitals of Isfahan. Overall, 401 inpatients were selected by cluster sampling and then selected simple random sampling from different wards. Data were collected through a questionnaire containing the components of patient dignity, that is, patient-nurse relationships, privacy, and independence. All items were scored based on a five-point Likert scale. The collected data were analyzed using descriptive statistics and Chi-square tests. P < 0.05 were considered significant in all analyses. Most patients (91%) scored their relationships with nurses as good. Moreover, 91.8% of the participants described privacy protection as moderate/good. Only 6.5% of the subjects rated it as excellent. The majority of the patients (84.4%) believed their independence was maintained. These subjects also approved of taking part in decision-making. According to our findings, nurses respected patient dignity to an acceptable level. However, the conditions were less favorable in public hospitals and emergency departments. Nursing authorities and policy makers are thus required to introduce appropriate measures to improve the existing conditions.
LeVine, Michael V; Weinstein, Harel
2015-05-01
In performing their biological functions, molecular machines must process and transmit information with high fidelity. Information transmission requires dynamic coupling between the conformations of discrete structural components within the protein positioned far from one another on the molecular scale. This type of biomolecular "action at a distance" is termed allostery . Although allostery is ubiquitous in biological regulation and signal transduction, its treatment in theoretical models has mostly eschewed quantitative descriptions involving the system's underlying structural components and their interactions. Here, we show how Ising models can be used to formulate an approach to allostery in a structural context of interactions between the constitutive components by building simple allosteric constructs we termed Allosteric Ising Models (AIMs). We introduce the use of AIMs in analytical and numerical calculations that relate thermodynamic descriptions of allostery to the structural context, and then show that many fundamental properties of allostery, such as the multiplicative property of parallel allosteric channels, are revealed from the analysis of such models. The power of exploring mechanistic structural models of allosteric function in more complex systems by using AIMs is demonstrated by building a model of allosteric signaling for an experimentally well-characterized asymmetric homodimer of the dopamine D2 receptor.
McCarty, J; Clark, A J; Copperman, J; Guenza, M G
2014-05-28
Structural and thermodynamic consistency of coarse-graining models across multiple length scales is essential for the predictive role of multi-scale modeling and molecular dynamic simulations that use mesoscale descriptions. Our approach is a coarse-grained model based on integral equation theory, which can represent polymer chains at variable levels of chemical details. The model is analytical and depends on molecular and thermodynamic parameters of the system under study, as well as on the direct correlation function in the k → 0 limit, c0. A numerical solution to the PRISM integral equations is used to determine c0, by adjusting the value of the effective hard sphere diameter, dHS, to agree with the predicted equation of state. This single quantity parameterizes the coarse-grained potential, which is used to perform mesoscale simulations that are directly compared with atomistic-level simulations of the same system. We test our coarse-graining formalism by comparing structural correlations, isothermal compressibility, equation of state, Helmholtz and Gibbs free energies, and potential energy and entropy using both united atom and coarse-grained descriptions. We find quantitative agreement between the analytical formalism for the thermodynamic properties, and the results of Molecular Dynamics simulations, independent of the chosen level of representation. In the mesoscale description, the potential energy of the soft-particle interaction becomes a free energy in the coarse-grained coordinates which preserves the excess free energy from an ideal gas across all levels of description. The structural consistency between the united-atom and mesoscale descriptions means the relative entropy between descriptions has been minimized without any variational optimization parameters. The approach is general and applicable to any polymeric system in different thermodynamic conditions.
USDA-ARS?s Scientific Manuscript database
A wide range of analytical techniques are available for the detection, quantitation, and evaluation of vitamin K in foods. The methods vary from simple to complex depending on extraction, separation, identification and detection of the analyte. Among the extraction methods applied for vitamin K anal...
Hamilton-Jacobi modelling of relative motion for formation flying.
Kolemen, Egemen; Kasdin, N Jeremy; Gurfil, Pini
2005-12-01
A precise analytic model for the relative motion of a group of satellites in slightly elliptic orbits is introduced. With this aim, we describe the relative motion of an object relative to a circular or slightly elliptic reference orbit in the rotating Hill frame via a low-order Hamiltonian, and solve the Hamilton-Jacobi equation. This results in a first-order solution to the relative motion identical to the Clohessy-Wiltshire approach; here, however, rather than using initial conditions as our constants of the motion, we utilize the canonical momenta and coordinates. This allows us to treat perturbations in an identical manner, as in the classical Delaunay formulation of the two-body problem. A precise analytical model for the base orbit is chosen with the included effect of zonal harmonics (J(2), J(3), J(4)). A Hamiltonian describing the real relative motion is formed and by differing this from the nominal Hamiltonian, the perturbing Hamiltonian is obtained. Using the Hamilton equations, the variational equations for the new constants are found. In a manner analogous to the center manifold reduction procedure, the non-periodic part of the motion is canceled through a magnitude analysis leading to simple boundedness conditions that cancel the drift terms due to the higher order perturbations. Using this condition, the variational equations are integrated to give periodic solutions that closely approximate the results from numerical integration (1 mm/per orbit for higher order and eccentricity perturbations and 30 cm/per orbit for zonal perturbations). This procedure provides a compact and insightful analytic description of the resulting relative motion.
Fuentes Alvarez, M D; Llorente Suárez, L; Bousquets Toral, L; Artimez, M L; Rodrigo Sáez, L
1995-11-01
To determine the prevalence of alcoholism in a rural area of Asturias and the usefulness of others clinical and analytical parameters for a rapid detection of its related pathology. We conducted a cross-sectional descriptive study on a sample of 198 persons, divided into two groups (Group I: Heavy-drinkers and Group II: Moderate and nondrinkers), according with alcohol daily intake. The limit for the classification was the consumption of 80 or more grams of ethanol/day in men, and 60 g/day or more in women. Data about physical findings and blood biochemistry were collected and compared into the two groups. The prevalence of alcoholism in group I, was of 16.5% and the mean age of 54.3 +/- 11.4 years with increased proportion of males over females with a ratio of 7.25/1. The main analytical parameters useful as indicators of heavy alcohol consumption were an increase of AST, ALT, GGT, Total Cholesterol, Uric acid and gammaglobulin levels. We found a significative relation between legal problems and alcohol consumption (p < 0.005) as well as an increased prevalence of chronic obstructive lung diseases (p < 0.005). Digestive diseases as a whole, were most frequently associated with heavy alcohol consumption. This paper confirms the finding of a increased alcohol consumption in this mainly agricultural area of Asturias (Spain) in 16.5% and also confirms the usefulness of the use of simple clinical and analytical parameters for its detection in order to permit an earlier diagnostic and better use of preventive measures.
Three lessons for genetic toxicology from baseball analytics.
Dertinger, Stephen D
2017-07-01
In many respects the evolution of baseball statistics mirrors advances made in the field of genetic toxicology. From its inception, baseball and statistics have been inextricably linked. Generations of players and fans have used a number of relatively simple measurements to describe team and individual player's current performance, as well as for historical record-keeping purposes. Over the years, baseball analytics has progressed in several important ways. Early advances were based on deriving more meaningful metrics from simpler forerunners. Now, technological innovations are delivering much deeper insights. Videography, radar, and other advances that include automatic player recognition capabilities provide the means to measure more complex and useful factors. Fielders' reaction times, efficiency of the route taken to reach a batted ball, and pitch-framing effectiveness come to mind. With the current availability of complex measurements from multiple data streams, multifactorial analyses occurring via machine learning algorithms have become necessary to make sense of the terabytes of data that are now being captured in every Major League Baseball game. Collectively, these advances have transformed baseball statistics from being largely descriptive in nature to serving data-driven, predictive roles. Whereas genetic toxicology has charted a somewhat parallel course, a case can be made that greater utilization of baseball's mindset and strategies would serve our scientific field well. This paper describes three useful lessons for genetic toxicology, courtesy of the field of baseball analytics: seek objective knowledge; incorporate multiple data streams; and embrace machine learning. Environ. Mol. Mutagen. 58:390-397, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.
Rodriguez-Mozaz, Sara; de Alda, Maria J López; Barceló, Damià
2006-04-15
This work describes the application of an optical biosensor (RIver ANALyser, RIANA) to the simultaneous analysis of three relevant environmental organic pollutants, namely, the pesticides atrazine and isoproturon and the estrogen estrone, in real water samples. This biosensor is based on an indirect inhibition immunoassay which takes place at a chemically modified optical transducer chip. The spatially resolved modification of the transducer surface allows the simultaneous determination of selected target analytes by means of "total internal reflection fluorescence" (TIRF). The performance of the immunosensor method developed was evaluated against a well accepted traditional method based on solid-phase extraction followed by liquid chromatography-mass spectrometry (LC-MS). The chromatographic method was superior in terms of linearity, sensitivity and accuracy, and the biosensor method in terms of repeatability, speed, cost and automation. The application of both methods in parallel to determine the occurrence and removal of atrazine, isoproturon and estrone throughout the treatment process (sand filtration, ozonation, activated carbon filtration and chlorination) in a waterworks showed an overestimation of results in the case of the biosensor, which was partially attributed to matrix and cross-reactivity effects, in spite of the addition of ovalbumin to the sample to minimize matrix interferences. Based on the comparative performance of both techniques, the biosensor emerges as a suitable tool for fast, simple and automated screening of water pollutants without sample pretreatment. To the author's knowledge, this is the first description of the application of the biosensor RIANA in the multi-analyte configuration to the regular monitoring of pollutants in a waterworks.
DidFail: Coverage and Precision Enhancement
2017-07-07
Android developer website [4] for a detailed description of these methods. To test this approach, we developed two example apps with different complexities...broadcast receivers by performing an extra analytical step to find dynamic receivers and append descriptions of them to the manifest file before the data
NASA Astrophysics Data System (ADS)
Kanoglu, U.; Wronna, M.; Baptista, M. A.; Miranda, J. M. A.
2017-12-01
The one-dimensional analytical runup theory in combination with near shore synthetic waveforms is a promising tool for tsunami rapid early warning systems. Its application in realistic cases with complex bathymetry and initial wave condition from inverse modelling have shown that maximum runup values can be estimated reasonably well. In this study we generate a simplistic bathymetry domains which resemble realistic near-shore features. We investigate the accuracy of the analytical runup formulae to the variation of fault source parameters and near-shore bathymetric features. To do this we systematically vary the fault plane parameters to compute the initial tsunami wave condition. Subsequently, we use the initial conditions to run the numerical tsunami model using coupled system of four nested grids and compare the results to the analytical estimates. Variation of the dip angle of the fault plane showed that analytical estimates have less than 10% difference for angles 5-45 degrees in a simple bathymetric domain. These results shows that the use of analytical formulae for fast run up estimates constitutes a very promising approach in a simple bathymetric domain and might be implemented in Hazard Mapping and Early Warning.
Stress Analysis of Beams with Shear Deformation of the Flanges
NASA Technical Reports Server (NTRS)
Kuhn, Paul
1937-01-01
This report discusses the fundamental action of shear deformation of the flanges on the basis of simplifying assumptions. The theory is developed to the point of giving analytical solutions for simple cases of beams and of skin-stringer panels under axial load. Strain-gage tests on a tension panel and on a beam corresponding to these simple cases are described and the results are compared with analytical results. For wing beams, an approximate method of applying the theory is given. As an alternative, the construction of a mechanical analyzer is advocated.
IBM Watson Analytics: Automating Visualization, Descriptive, and Predictive Statistics
2016-01-01
Background We live in an era of explosive data generation that will continue to grow and involve all industries. One of the results of this explosion is the need for newer and more efficient data analytics procedures. Traditionally, data analytics required a substantial background in statistics and computer science. In 2015, International Business Machines Corporation (IBM) released the IBM Watson Analytics (IBMWA) software that delivered advanced statistical procedures based on the Statistical Package for the Social Sciences (SPSS). The latest entry of Watson Analytics into the field of analytical software products provides users with enhanced functions that are not available in many existing programs. For example, Watson Analytics automatically analyzes datasets, examines data quality, and determines the optimal statistical approach. Users can request exploratory, predictive, and visual analytics. Using natural language processing (NLP), users are able to submit additional questions for analyses in a quick response format. This analytical package is available free to academic institutions (faculty and students) that plan to use the tools for noncommercial purposes. Objective To report the features of IBMWA and discuss how this software subjectively and objectively compares to other data mining programs. Methods The salient features of the IBMWA program were examined and compared with other common analytical platforms, using validated health datasets. Results Using a validated dataset, IBMWA delivered similar predictions compared with several commercial and open source data mining software applications. The visual analytics generated by IBMWA were similar to results from programs such as Microsoft Excel and Tableau Software. In addition, assistance with data preprocessing and data exploration was an inherent component of the IBMWA application. Sensitivity and specificity were not included in the IBMWA predictive analytics results, nor were odds ratios, confidence intervals, or a confusion matrix. Conclusions IBMWA is a new alternative for data analytics software that automates descriptive, predictive, and visual analytics. This program is very user-friendly but requires data preprocessing, statistical conceptual understanding, and domain expertise. PMID:27729304
IBM Watson Analytics: Automating Visualization, Descriptive, and Predictive Statistics.
Hoyt, Robert Eugene; Snider, Dallas; Thompson, Carla; Mantravadi, Sarita
2016-10-11
We live in an era of explosive data generation that will continue to grow and involve all industries. One of the results of this explosion is the need for newer and more efficient data analytics procedures. Traditionally, data analytics required a substantial background in statistics and computer science. In 2015, International Business Machines Corporation (IBM) released the IBM Watson Analytics (IBMWA) software that delivered advanced statistical procedures based on the Statistical Package for the Social Sciences (SPSS). The latest entry of Watson Analytics into the field of analytical software products provides users with enhanced functions that are not available in many existing programs. For example, Watson Analytics automatically analyzes datasets, examines data quality, and determines the optimal statistical approach. Users can request exploratory, predictive, and visual analytics. Using natural language processing (NLP), users are able to submit additional questions for analyses in a quick response format. This analytical package is available free to academic institutions (faculty and students) that plan to use the tools for noncommercial purposes. To report the features of IBMWA and discuss how this software subjectively and objectively compares to other data mining programs. The salient features of the IBMWA program were examined and compared with other common analytical platforms, using validated health datasets. Using a validated dataset, IBMWA delivered similar predictions compared with several commercial and open source data mining software applications. The visual analytics generated by IBMWA were similar to results from programs such as Microsoft Excel and Tableau Software. In addition, assistance with data preprocessing and data exploration was an inherent component of the IBMWA application. Sensitivity and specificity were not included in the IBMWA predictive analytics results, nor were odds ratios, confidence intervals, or a confusion matrix. IBMWA is a new alternative for data analytics software that automates descriptive, predictive, and visual analytics. This program is very user-friendly but requires data preprocessing, statistical conceptual understanding, and domain expertise.
ERIC Educational Resources Information Center
Brennan, Tim
1980-01-01
A review of prior classification systems of runaways is followed by a descriptive taxonomy of runaways developed using cluster-analytic methods. The empirical types illustrate patterns of weakness in bonds between runaways and families, schools, or peer relationships. (Author)
Analytical Models of Legislative Texts for Muslim Scholars
ERIC Educational Resources Information Center
Alwan, Ammar Abdullah Naseh; Yusoff, Mohd Yakubzulkifli Bin Mohd; Al-Hami, Mohammad Said M.
2011-01-01
The significance of the analytical models in traditional Islamic studies is that they contribute in sharpening the intellectual capacity of the students of Islamic studies. Research literature in Islamic studies has descriptive side predominantly; the information is gathered and compiled and rarely analyzed properly. This weakness is because of…
Analytic and Heuristic Processing Influences on Adolescent Reasoning and Decision-Making.
ERIC Educational Resources Information Center
Klaczynski, Paul A.
2001-01-01
Examined the relationship between age and the normative/descriptive gap--the discrepancy between actual reasoning and traditional standards for reasoning. Found that middle adolescents performed closer to normative ideals than early adolescents. Factor analyses suggested that performance was based on two processing systems, analytic and heuristic…
A Simple Analytical Model for Magnetization and Coercivity of Hard/Soft Nanocomposite Magnets
DOE Office of Scientific and Technical Information (OSTI.GOV)
Park, Jihoon; Hong, Yang-Ki; Lee, Woncheol
Here, we present a simple analytical model to estimate the magnetization (σ s) and intrinsic coercivity (Hci) of a hard/soft nanocomposite magnet using the mass fraction. Previously proposed models are based on the volume fraction of the hard phase of the composite. But, it is difficult to measure the volume of the hard or soft phase material of a composite. We synthesized Sm 2Co 7/Fe-Co, MnAl/Fe-Co, MnBi/Fe-Co, and BaFe 12O 19/Fe-Co composites for characterization of their σs and Hci. The experimental results are in good agreement with the present model. Therefore, this analytical model can be extended to predict themore » maximum energy product (BH) max of hard/soft composite.« less
A Simple Analytical Model for Magnetization and Coercivity of Hard/Soft Nanocomposite Magnets
Park, Jihoon; Hong, Yang-Ki; Lee, Woncheol; ...
2017-07-10
Here, we present a simple analytical model to estimate the magnetization (σ s) and intrinsic coercivity (Hci) of a hard/soft nanocomposite magnet using the mass fraction. Previously proposed models are based on the volume fraction of the hard phase of the composite. But, it is difficult to measure the volume of the hard or soft phase material of a composite. We synthesized Sm 2Co 7/Fe-Co, MnAl/Fe-Co, MnBi/Fe-Co, and BaFe 12O 19/Fe-Co composites for characterization of their σs and Hci. The experimental results are in good agreement with the present model. Therefore, this analytical model can be extended to predict themore » maximum energy product (BH) max of hard/soft composite.« less
Experimenting with Impacts in a Conceptual Physics or Descriptive Astronomy Laboratory
ERIC Educational Resources Information Center
LoPresto, Michael C.
2016-01-01
What follows is a description of the procedure for and results of a simple experiment on the formation of impact craters designed for the laboratory portions of lower mathematical-level general education science courses such as conceptual physics or descriptive astronomy. The experiment provides necessary experience with data collection and…
A Systematic Study of Simple Combinatorial Configurations.
ERIC Educational Resources Information Center
Dubois, Jean-Guy
1984-01-01
A classification of the simple combinatorial configurations which correspond to various cases of distribution and ordering of objects into boxes is given (in French). Concrete descriptions, structured relations, translations, and formalizations are discussed. (MNS)
Analytical and Experimental Study of Near-Threshold Interactions Between Crack Closure Mechanisms
NASA Technical Reports Server (NTRS)
Newman, John A.; Riddell, William T.; Piascik, Robert S.
2003-01-01
The results of an analytical closure model that considers contributions and interactions between plasticity-, roughness-, and oxide-induced crack closure mechanisms are presented and compared with experimental data. The analytical model is shown to provide a good description of the combined influences of crack roughness, oxide debris, and plasticity in the near-threshold regime. Furthermore, analytical results indicate that closure mechanisms interact in a non-linear manner such that the total amount of closure is not the sum of closure contributions for each mechanism.
Basic Western Lviv Region Conversational Ukrainian
ERIC Educational Resources Information Center
Petryshyn, Ivan
2015-01-01
Purpose: To present the first complete Guide for studying the Western-Ukrainian Dialect and its scientific description of Phonology. Methodology: descriptive, contrastive and analytical methods of defining the peculiarities of the Dialect. Results: the regularities and the laws have been defined as to the specifics of the Western-Ukrainian Dialect…
Modern Instrumental Methods in Forensic Toxicology*
Smith, Michael L.; Vorce, Shawn P.; Holler, Justin M.; Shimomura, Eric; Magluilo, Joe; Jacobs, Aaron J.; Huestis, Marilyn A.
2009-01-01
This article reviews modern analytical instrumentation in forensic toxicology for identification and quantification of drugs and toxins in biological fluids and tissues. A brief description of the theory and inherent strengths and limitations of each methodology is included. The focus is on new technologies that address current analytical limitations. A goal of this review is to encourage innovations to improve our technological capabilities and to encourage use of these analytical techniques in forensic toxicology practice. PMID:17579968
Engine Structures Modeling Software System (ESMOSS)
NASA Technical Reports Server (NTRS)
1991-01-01
Engine Structures Modeling Software System (ESMOSS) is the development of a specialized software system for the construction of geometric descriptive and discrete analytical models of engine parts, components, and substructures which can be transferred to finite element analysis programs such as NASTRAN. The NASA Lewis Engine Structures Program is concerned with the development of technology for the rational structural design and analysis of advanced gas turbine engines with emphasis on advanced structural analysis, structural dynamics, structural aspects of aeroelasticity, and life prediction. Fundamental and common to all of these developments is the need for geometric and analytical model descriptions at various engine assembly levels which are generated using ESMOSS.
NASA Astrophysics Data System (ADS)
Baird, M. E.; Walker, S. J.; Wallace, B. B.; Webster, I. T.; Parslow, J. S.
2003-03-01
A simple model of estuarine eutrophication is built on biomechanical (or mechanistic) descriptions of a number of the key ecological processes in estuaries. Mechanistically described processes include the nutrient uptake and light capture of planktonic and benthic autotrophs, and the encounter rates of planktonic predators and prey. Other more complex processes, such as sediment biogeochemistry, detrital processes and phosphate dynamics, are modelled using empirical descriptions from the Port Phillip Bay Environmental Study (PPBES) ecological model. A comparison is made between the mechanistically determined rates of ecological processes and the analogous empirically determined rates in the PPBES ecological model. The rates generally agree, with a few significant exceptions. Model simulations were run at a range of estuarine depths and nutrient loads, with outputs presented as the annually averaged biomass of autotrophs. The simulations followed a simple conceptual model of eutrophication, suggesting a simple biomechanical understanding of estuarine processes can provide a predictive tool for ecological processes in a wide range of estuarine ecosystems.
Thermo-elastic wave model of the photothermal and photoacoustic signal
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meja, P.; Steiger, B.; Delsanto, P.P.
1996-12-31
By means of the thermo-elastic wave equation the dynamical propagation of mechanical stress and temperature can be described and applied to model the photothermal and photoacoustic signal. Analytical solutions exist only in particular cases. Using massively parallel computers it is possible to simulate the photothermal and photoacoustic signal in a most sufficient way. In this paper the method of local interaction simulation approach (LISA) is presented and selected examples of its application are given. The advantages of this method, which is particularly suitable for parallel processing, consist in reduced computation time and simple description of the photoacoustic signal in opticalmore » materials. The present contribution introduces the authors model, the formalism and some results in the 1 D case for homogeneous nonattenuative materials. The photoacoustic wave can be understood as a wave with locally limited displacement. This displacement corresponds to a temperature variation. Both variables are usually measured in photoacoustics and photothermal measurements. Therefore the temperature and displacement dependence on optical, elastic and thermal constants is analysed.« less
NASA Astrophysics Data System (ADS)
Iskandar, I.
2018-03-01
The exponential distribution is the most widely used reliability analysis. This distribution is very suitable for representing the lengths of life of many cases and is available in a simple statistical form. The characteristic of this distribution is a constant hazard rate. The exponential distribution is the lower rank of the Weibull distributions. In this paper our effort is to introduce the basic notions that constitute an exponential competing risks model in reliability analysis using Bayesian analysis approach and presenting their analytic methods. The cases are limited to the models with independent causes of failure. A non-informative prior distribution is used in our analysis. This model describes the likelihood function and follows with the description of the posterior function and the estimations of the point, interval, hazard function, and reliability. The net probability of failure if only one specific risk is present, crude probability of failure due to a specific risk in the presence of other causes, and partial crude probabilities are also included.
Large-aspect-ratio limit of neoclassical transport theory.
Wong, S K; Chan, V S
2003-06-01
This paper presents a comprehensive description of neoclassical transport theory in the banana regime for large-aspect-ratio flux surfaces of arbitrary shapes. The method of matched-asymptotic expansions is used to obtain analytical solutions for plasma distribution functions and to compute transport coefficients. The method provides justification for retaining only the part of the Fokker-Planck operator that involves the second derivative with respect to the cosine of the pitch angle for the trapped and barely circulating particles. It leads to a simple equation for the freely circulating particles with boundary conditions that embody a discontinuity separating particles moving in opposite directions. Corrections to the transport coefficients are obtained by generalizing an existing boundary layer analysis. The system of moment and field equations is consistently taken in the cylinder limit, which facilitates the discussion of the treatment of dynamical constraints. It is shown that the nonlocal nature of Ohm's law in neoclassical theory renders the mathematical problem of plasma transport with changing flux surfaces nonstandard.
Axisymmetric plasma equilibria in a Kerr metric
NASA Astrophysics Data System (ADS)
Elsässer, Klaus
2001-10-01
Plasma equilibria near a rotating black hole are considered within the multifluid description. An isothermal two-component plasma with electrons and positrons or ions is determined by four structure functions and the boundary conditions. These structure functions are the Bernoulli function and the toroidal canonical momentum per mass for each species. The quasi-neutrality assumption (no charge density, no toroidal current) allows to solve Maxwell's equations analytically for any axisymmetric stationary metric, and to reduce the fluid equations to one single scalar equation for the stream function \\chi of the positrons or ions, respectively. The basic smallness parameter is the ratio of the skin depth of electrons to the scale length of the metric and fluid quantities, and, in the case of an electron-ion plasma, the mass ratio m_e/m_i. The \\chi-equation can be solved by standard methods, and simple solutions for a Kerr geometry are available; they show characteristic flow patterns, depending on the structure functions and the boundary conditions.
Silica-Coated Plasmonic Metal Nanoparticles in Action.
Hanske, Christoph; Sanz-Ortiz, Marta N; Liz-Marzán, Luis M
2018-05-07
Hybrid colloids consisting of noble metal cores and metal oxide shells have been under intense investigation for over two decades and have driven progress in diverse research lines including sensing, medicine, catalysis, and photovoltaics. Consequently, plasmonic core-shell particles have come to play a vital role in a plethora of applications. Here, an overview is provided of recent developments in the design and utilization of the most successful class of such hybrid materials, silica-coated plasmonic metal nanoparticles. Besides summarizing common simple approaches to silica shell growth, special emphasis is put on advanced synthesis routes that either overcome typical limitations of classical methods, such as stability issues and undefined silica porosity, or grant access to particularly sophisticated nanostructures. Hereby, a description is given, how different types of silica can be used to provide noble metal particles with specific functionalities. Finally, applications of such nanocomposites in ultrasensitive analyte detection, theranostics, catalysts, and thin-film solar cells are reviewed. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kyriakou, Ioanna; Emfietzoglou, Dimitris; Nojeh, Alireza
A systematic study of electron-beam penetration and backscattering in multi-walled carbon nanotube (MWCNT) materials for beam energies of {approx}0.3 to 30 keV is presented based on event-by-event Monte Carlo simulation of electron trajectories using state-of-the-art scattering cross sections. The importance of different analytic approximations for computing the elastic and inelastic electron-scattering cross sections for MWCNTs is emphasized. We offer a simple parameterization for the total and differential elastic-scattering Mott cross section, using appropriate modifications to the Browning formula and the Thomas-Fermi screening parameter. A discrete-energy-loss approach to inelastic scattering based on dielectric theory is adopted using different descriptions of themore » differential cross section. The sensitivity of electron penetration and backscattering parameters to the underlying scattering models is examined. Our simulations confirm the recent experimental backscattering data on MWCNT forests and, in particular, the steep increase of the backscattering yield at sub-keV energies as well as the sidewalls escape effect at high-beam energies.« less
Markov Chain Monte Carlo: an introduction for epidemiologists
Hamra, Ghassan; MacLehose, Richard; Richardson, David
2013-01-01
Markov Chain Monte Carlo (MCMC) methods are increasingly popular among epidemiologists. The reason for this may in part be that MCMC offers an appealing approach to handling some difficult types of analyses. Additionally, MCMC methods are those most commonly used for Bayesian analysis. However, epidemiologists are still largely unfamiliar with MCMC. They may lack familiarity either with he implementation of MCMC or with interpretation of the resultant output. As with tutorials outlining the calculus behind maximum likelihood in previous decades, a simple description of the machinery of MCMC is needed. We provide an introduction to conducting analyses with MCMC, and show that, given the same data and under certain model specifications, the results of an MCMC simulation match those of methods based on standard maximum-likelihood estimation (MLE). In addition, we highlight examples of instances in which MCMC approaches to data analysis provide a clear advantage over MLE. We hope that this brief tutorial will encourage epidemiologists to consider MCMC approaches as part of their analytic tool-kit. PMID:23569196
HIV/AIDS knowledge and occupational risk in primary care health workers from Chile
Valdés, Baltica Cabieses; Lagunas, Lilian Ferrer; Villarroel, Luis Antonio; Acosta, Rosina Cianelli; Miner, Sarah; Silva, Margarita Bernales
2014-01-01
Objective To explore the relationship between knowledge level and occupational risk exposure to HIV/AIDS in primary care health workers. Methodology Analytical cross-sectional study. 720 health workers from Santiago answered a survey about HIV/AIDS that included: knowledge level (appropriate, inappropriate), occupational risk (with or without risk), and control variables (age, gender, health center, education and marital status). Descriptive and association analysis were performed. Odds Ratio (OR) was estimated through simple and multiple regressions logistics. Results 58.7% of the participants reported HIV occupational risk. 63.8% of the participants from the exposed group reported an appropriate level of knowledge, versus 36.1% of the non-exposed group (Adjusted OR of 3.1, IC95%OR: 2.0-4.8, p<0.0001). Technicians and cleaning staff reported a lower proportion of appropriate level of knowledge compared to the employees with college education (p<0.0001). Conclusion The level of HIV/AID occupational risk is directly associated with the level of knowledge of the disease. PMID:25284913
40 CFR 89.412 - Raw gaseous exhaust sampling and analytical system description.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Raw gaseous exhaust sampling and...-IGNITION ENGINES Exhaust Emission Test Procedures § 89.412 Raw gaseous exhaust sampling and analytical... must be incorporated in each system used for raw testing under this subpart. (1) [Reserved] (2) The...
40 CFR 89.412 - Raw gaseous exhaust sampling and analytical system description.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Raw gaseous exhaust sampling and...-IGNITION ENGINES Exhaust Emission Test Procedures § 89.412 Raw gaseous exhaust sampling and analytical... must be incorporated in each system used for raw testing under this subpart. (1) [Reserved] (2) The...
NASA Technical Reports Server (NTRS)
Meyers, A. P.; Davidson, W. A.; Gortowski, R. C.
1973-01-01
Detailed drawings of the five year tape transport are presented. Analytical tools used in the various analyses are described. These analyses include: tape guidance, tape stress over crowned rollers, tape pack stress program, response (computer) program, and control system electronics description.
Fire behavior modeling-a decision tool
Jack Cohen; Bill Bradshaw
1986-01-01
The usefulness of an analytical model as a fire management decision tool is determined by the correspondence of its descriptive capability to the specific decision context. Fire managers must determine the usefulness of fire models as a decision tool when applied to varied situations. Because the wildland fire phenomenon is complex, analytical fire spread models will...
Experimental and analytical characterization of triaxially braided textile composites
NASA Technical Reports Server (NTRS)
Masters, John E.; Fedro, Mark J.; Ifju, Peter G.
1993-01-01
There were two components, experimental and analytical, to this investigation of triaxially braided textile composite materials. The experimental portion of the study centered on measuring the materials' longitudinal and transverse tensile moduli, Poisson's ratio, and strengths. The identification of the damage mechanisms exhibited by these materials was also a prime objective of the experimental investigation. The analytical portion of the investigation utilized the Textile Composites Analysis (TECA) model to predict modulus and strength. The analytical and experimental results were compared to assess the effectiveness of the analysis. The figures contained in this paper reflect the presentation made at the conference. They may be divided into four sections: a definition of the material system tested; followed by a series of figures summarizing the experimental results (these figures contain results of a Moire interferometry study of the strain distribution in the material, examples and descriptions of the types of damage encountered in these materials, and a summary of the measured properties); a description of the TECA model follows the experimental results (this includes a series of predicted results and a comparison with measured values); and finally, a brief summary completes the paper.
A Simple Analytic Model for Estimating Mars Ascent Vehicle Mass and Performance
NASA Technical Reports Server (NTRS)
Woolley, Ryan C.
2014-01-01
The Mars Ascent Vehicle (MAV) is a crucial component in any sample return campaign. In this paper we present a universal model for a two-stage MAV along with the analytic equations and simple parametric relationships necessary to quickly estimate MAV mass and performance. Ascent trajectories can be modeled as two-burn transfers from the surface with appropriate loss estimations for finite burns, steering, and drag. Minimizing lift-off mass is achieved by balancing optimized staging and an optimized path-to-orbit. This model allows designers to quickly find optimized solutions and to see the effects of design choices.
Sigalov, G; Gendelman, O V; AL-Shudeifat, M A; Manevitch, L I; Vakakis, A F; Bergman, L A
2012-03-01
We show that nonlinear inertial coupling between a linear oscillator and an eccentric rotator can lead to very interesting interchanges between regular and chaotic dynamical behavior. Indeed, we show that this model demonstrates rather unusual behavior from the viewpoint of nonlinear dynamics. Specifically, at a discrete set of values of the total energy, the Hamiltonian system exhibits non-conventional nonlinear normal modes, whose shape is determined by phase locking of rotatory and oscillatory motions of the rotator at integer ratios of characteristic frequencies. Considering the weakly damped system, resonance capture of the dynamics into the vicinity of these modes brings about regular motion of the system. For energy levels far from these discrete values, the motion of the system is chaotic. Thus, the succession of resonance captures and escapes by a discrete set of the normal modes causes a sequence of transitions between regular and chaotic behavior, provided that the damping is sufficiently small. We begin from the Hamiltonian system and present a series of Poincaré sections manifesting the complex structure of the phase space of the considered system with inertial nonlinear coupling. Then an approximate analytical description is presented for the non-conventional nonlinear normal modes. We confirm the analytical results by numerical simulation and demonstrate the alternate transitions between regular and chaotic dynamics mentioned above. The origin of the chaotic behavior is also discussed.
Maximum Likelihood Time-of-Arrival Estimation of Optical Pulses via Photon-Counting Photodetectors
NASA Technical Reports Server (NTRS)
Erkmen, Baris I.; Moision, Bruce E.
2010-01-01
Many optical imaging, ranging, and communications systems rely on the estimation of the arrival time of an optical pulse. Recently, such systems have been increasingly employing photon-counting photodetector technology, which changes the statistics of the observed photocurrent. This requires time-of-arrival estimators to be developed and their performances characterized. The statistics of the output of an ideal photodetector, which are well modeled as a Poisson point process, were considered. An analytical model was developed for the mean-square error of the maximum likelihood (ML) estimator, demonstrating two phenomena that cause deviations from the minimum achievable error at low signal power. An approximation was derived to the threshold at which the ML estimator essentially fails to provide better than a random guess of the pulse arrival time. Comparing the analytic model performance predictions to those obtained via simulations, it was verified that the model accurately predicts the ML performance over all regimes considered. There is little prior art that attempts to understand the fundamental limitations to time-of-arrival estimation from Poisson statistics. This work establishes both a simple mathematical description of the error behavior, and the associated physical processes that yield this behavior. Previous work on mean-square error characterization for ML estimators has predominantly focused on additive Gaussian noise. This work demonstrates that the discrete nature of the Poisson noise process leads to a distinctly different error behavior.
Arrays of strongly coupled atoms in a one-dimensional waveguide
NASA Astrophysics Data System (ADS)
Ruostekoski, Janne; Javanainen, Juha
2017-09-01
We study the cooperative optical coupling between regularly spaced atoms in a one-dimensional waveguide using decompositions to subradiant and super-radiant collective excitation eigenmodes, direct numerical solutions, and analytical transfer-matrix methods. We illustrate how the spectrum of transmitted light through the waveguide, including the emergence of narrow Fano resonances, can be understood by the resonance features of the eigenmodes. We describe a method based on super-radiant and subradiant modes to engineer the optical response of the waveguide and to store light. The stopping of light is obtained by transferring an atomic excitation to a subradiant collective mode with the zero radiative resonance linewidth by controlling the level shift of an atom in the waveguide. Moreover, we obtain an exact analytic solution for the transmitted light through the waveguide for the case of a regular lattice of atoms and provide a simple description of how the light transmission may present large resonance shifts when the lattice spacing is close, but not exactly equal, to half of the wavelength of the light. Experimental imperfections such as fluctuations of the positions of the atoms and loss of light from the waveguide are easily quantified in the numerical simulations, which produce the natural result that the optical response of the atomic array tends toward the response of a gas with random atomic positions.
Frank, Nancy; Bessaire, Thomas; Tarres, Adrienne; Goyon, Alexandre; Delatour, Thierry
2017-11-01
The increasing number of food frauds using exogenous nitrogen-rich adulterants to artificially raise the protein content for economically motivated adulteration has demonstrated the need for a robust analytical methodology. This method should be applicable for quality control in operations covering a wide range of analyte concentrations to be able to analyse high levels as usually found in adulteration, as well as low levels due to contamination. The paper describes a LC-MS/MS method covering 14 nitrogen-rich adulterants using a simple and fast sample preparation based on dilution and clean-up by dispersive SPE. Quantification is carried out by isotopic dilution reaching LOQs of 0.05-0.20 mg/kg in a broad range of food matrices (infant formula, liquid milk, dairy ingredient, high protein meal, cereal, infant cereal, and meat/fish powder). Validation of seven commodity groups was performed according to SANCO 12571/2013, giving satisfactory results demonstrating the method's fitness for purpose at the validated range at contamination level. Method ruggedness was further assessed by transferring the developed method into another laboratory devoted to routine testing for quality control. Next to the method description, emphasis is placed on challenges and problems appearing during method development as well as validation. They are discussed in detail and solutions are provided.
On the analytical form of the Earth's magnetic attraction expressed as a function of time
NASA Technical Reports Server (NTRS)
Carlheim-Gyllenskold, V.
1983-01-01
An attempt is made to express the Earth's magnetic attraction in simple analytical form using observations during the 16th to 19th centuries. Observations of the magnetic inclination in the 16th and 17th centuries are discussed.
Systematic Review of Model-Based Economic Evaluations of Treatments for Alzheimer's Disease.
Hernandez, Luis; Ozen, Asli; DosSantos, Rodrigo; Getsios, Denis
2016-07-01
Numerous economic evaluations using decision-analytic models have assessed the cost effectiveness of treatments for Alzheimer's disease (AD) in the last two decades. It is important to understand the methods used in the existing models of AD and how they could impact results, as they could inform new model-based economic evaluations of treatments for AD. The aim of this systematic review was to provide a detailed description on the relevant aspects and components of existing decision-analytic models of AD, identifying areas for improvement and future development, and to conduct a quality assessment of the included studies. We performed a systematic and comprehensive review of cost-effectiveness studies of pharmacological treatments for AD published in the last decade (January 2005 to February 2015) that used decision-analytic models, also including studies considering patients with mild cognitive impairment (MCI). The background information of the included studies and specific information on the decision-analytic models, including their approach and components, assumptions, data sources, analyses, and results, were obtained from each study. A description of how the modeling approaches and assumptions differ across studies, identifying areas for improvement and future development, is provided. At the end, we present our own view of the potential future directions of decision-analytic models of AD and the challenges they might face. The included studies present a variety of different approaches, assumptions, and scope of decision-analytic models used in the economic evaluation of pharmacological treatments of AD. The major areas for improvement in future models of AD are to include domains of cognition, function, and behavior, rather than cognition alone; include a detailed description of how data used to model the natural course of disease progression were derived; state and justify the economic model selected and structural assumptions and limitations; provide a detailed (rather than high-level) description of the cost components included in the model; and report on the face-, internal-, and cross-validity of the model to strengthen the credibility and confidence in model results. The quality scores of most studies were rated as fair to good (average 87.5, range 69.5-100, in a scale of 0-100). Despite the advancements in decision-analytic models of AD, there remain several areas of improvement that are necessary to more appropriately and realistically capture the broad nature of AD and the potential benefits of treatments in future models of AD.
Bagheri, Pezhman; Mohammadi, Mohammad Reza; Shafiei, Nematollah
2017-06-01
Several documents have investigated the area of Quran study and medicine from different points of view; the present study has been assessing all the documents about Quran study and medicine, published in Iranian scientific-research journals, to create an opportunity of revising the interventions executed in this areas and targeting the decisions in order to draw a clear and more realistic vision. In this simple review study, scientific-research and general informative websites in the period of 1992-2013 were explored by taking advantage of critical keywords such as Islamic medicine and Islamic lifestyle. After the initial retrieval, 348 articles were finally ready for the evaluation process. Chi-square test was used to assess the significance of patterns differences between years of study. Minimum and maximum numbers of articles were published in 1992 (0.28 %) and 2011 (12.35 %), respectively. The level of execution of studies by using different methods was as follows: about 3.44 % qualitative, 29.59 % cross-sectional descriptive-analytical, 30.45 % review, 1.14 % case-control, 17.52 % experimental, 3.73 % cohort methods and 12.93 % were performed by other methods. The most common subject study was "The effects of fasting and Ramadan on health" (21.83 %). The most important journals hosting this field articles were the journals of medicine and refinement (27.01 %), as well as the Quran and medicine (12.64 %), respectively. Chi-square test showed significant thematic differences during the 21 years of study. Based on the available evidences, the number of descriptive papers was yet more than the analytical, interventional and scientific-comparative articles. Also, the most studies had been reviewing the medical-Islamic documents. This reflects the need for revising the search strategies of Quran study and medicine.
Schwertfeger, D M; Velicogna, Jessica R; Jesmer, Alexander H; Scroggins, Richard P; Princz, Juliska I
2016-10-18
There is an increasing interest to use single particle-inductively coupled plasma mass spectroscopy (SP-ICPMS) to help quantify exposure to engineered nanoparticles, and their transformation products, released into the environment. Hindering the use of this analytical technique for environmental samples is the presence of high levels of dissolved analyte which impedes resolution of the particle signal from the dissolved. While sample dilution is often necessary to achieve the low analyte concentrations necessary for SP-ICPMS analysis, and to reduce the occurrence of matrix effects on the analyte signal, it is used here to also reduce the dissolved signal relative to the particulate, while maintaining a matrix chemistry that promotes particle stability. We propose a simple, systematic dilution series approach where by the first dilution is used to quantify the dissolved analyte, the second is used to optimize the particle signal, and the third is used as an analytical quality control. Using simple suspensions of well characterized Au and Ag nanoparticles spiked with the dissolved analyte form, as well as suspensions of complex environmental media (i.e., extracts from soils previously contaminated with engineered silver nanoparticles), we show how this dilution series technique improves resolution of the particle signal which in turn improves the accuracy of particle counts, quantification of particulate mass and determination of particle size. The technique proposed here is meant to offer a systematic and reproducible approach to the SP-ICPMS analysis of environmental samples and improve the quality and consistency of data generated from this relatively new analytical tool.
Hertäg, Loreen; Durstewitz, Daniel; Brunel, Nicolas
2014-01-01
Computational models offer a unique tool for understanding the network-dynamical mechanisms which mediate between physiological and biophysical properties, and behavioral function. A traditional challenge in computational neuroscience is, however, that simple neuronal models which can be studied analytically fail to reproduce the diversity of electrophysiological behaviors seen in real neurons, while detailed neuronal models which do reproduce such diversity are intractable analytically and computationally expensive. A number of intermediate models have been proposed whose aim is to capture the diversity of firing behaviors and spike times of real neurons while entailing the simplest possible mathematical description. One such model is the exponential integrate-and-fire neuron with spike rate adaptation (aEIF) which consists of two differential equations for the membrane potential (V) and an adaptation current (w). Despite its simplicity, it can reproduce a wide variety of physiologically observed spiking patterns, can be fit to physiological recordings quantitatively, and, once done so, is able to predict spike times on traces not used for model fitting. Here we compute the steady-state firing rate of aEIF in the presence of Gaussian synaptic noise, using two approaches. The first approach is based on the 2-dimensional Fokker-Planck equation that describes the (V,w)-probability distribution, which is solved using an expansion in the ratio between the time constants of the two variables. The second is based on the firing rate of the EIF model, which is averaged over the distribution of the w variable. These analytically derived closed-form expressions were tested on simulations from a large variety of model cells quantitatively fitted to in vitro electrophysiological recordings from pyramidal cells and interneurons. Theoretical predictions closely agreed with the firing rate of the simulated cells fed with in-vivo-like synaptic noise.
Malá, Zdena; Gebauer, Petr
2018-01-15
This work describes for the first time a functional electrolyte system setup for anionic isotachophoresis (ITP) with electrospray-ionization mass-spectrometric (ESI-MS) detection in the neutral to medium-alkaline pH range. So far no application was published on the analysis of very weak acids by anionic ITP-MS although there is a broad spectrum of potential analytes with pK a values in the range 5-10, where application of this technique promises interesting gains in both sensitivity and specificity. The problem so far was the lack of anionic ESI-compatible ITP systems in the mentioned pH range as all typical volatile anionic system components are fully ionized at neutral and alkaline pH and thus too fast to suit as terminators. We propose an original solution of the problem based on the combination of two ITP methods: (i) use of the hydroxyl ion as a natural and ESI-compatible terminator, and (ii) use of configurations based on moving-boundary ITP. The former method ensures effective stacking of analytes by an alkaline terminator of sufficiently low mobility and the latter offers increased flexibility for tuning of the separation window and selectivity according to actual needs. A theoretical description of the proposed model is presented and applied to the design of very simple functional electrolyte configurations. The properties of example systems are demonstrated by both computer simulation and experiments with a group of model analytes. Potential effects of carbon dioxide present in the solutions are demonstrated for particular systems. Experimental results confirm that the proposed methodology is well capable of performing sensitive and selective ITP-MS analyses of very weak acidic analytes (e.g. sulfonamides or chlorophenols). Copyright © 2017 Elsevier B.V. All rights reserved.
Phonon scattering in nanoscale systems: lowest order expansion of the current and power expressions
NASA Astrophysics Data System (ADS)
Paulsson, Magnus; Frederiksen, Thomas; Brandbyge, Mads
2006-04-01
We use the non-equilibrium Green's function method to describe the effects of phonon scattering on the conductance of nano-scale devices. Useful and accurate approximations are developed that both provide (i) computationally simple formulas for large systems and (ii) simple analytical models. In addition, the simple models can be used to fit experimental data and provide physical parameters.
The Soil Foam Drainage Equation - an alternative model for unsaturated flow in porous media
NASA Astrophysics Data System (ADS)
Assouline, Shmuel; Lehmann, Peter; Hoogland, Frouke; Or, Dani
2017-04-01
The analogy between the geometry and dynamics of wet foam drainage and gravity drainage of unsaturated porous media expands modeling capabilities for capillary flows and supplements the standard Richards equation representation. The governing equation for draining foam (or a soil variant termed the soil foam drainage equation - SFDE) obviates the need for macroscopic unsaturated hydraulic conductivity function by an explicit account of diminishing flow pathway sizes as the medium gradually drains. Potential advantages of the proposed drainage foam formalism include direct description of transient flow without requiring constitutive functions; evolution of capillary cross sections that provides consistent description of self-regulating internal fluxes (e.g., towards field capacity); and a more intuitive geometrical picture of capillary flow across textural boundaries. We will present new and simple analytical expressions for drainage rates and volumes from unsaturated porous media subjected to different boundary conditions that are in good agreement with the numerical solution of the SFDE and experimental results. The foam drainage methodology expands the range of tools available for describing and quantifying unsaturated flows and provides geometrically tractable links between evolution of liquid configuration and flow dynamics in unsaturated porous media. The resulting geometrical representation of capillary drainage could improve understanding of colloid and pathogen transport. The explicit geometrical interpretation of flow pathways underlying the hydraulic functions used by the Richards equation offers new insights that benefit both approaches.
Fischhoff, Baruch
2010-09-01
The study of judgment and decision making entails three interrelated forms of research: (1) normative analysis, identifying the best courses of action, given decision makers' values; (2) descriptive studies, examining actual behavior in terms comparable to the normative analyses; and (3) prescriptive interventions, helping individuals to make better choices, bridging the gap between the normative ideal and the descriptive reality. The research is grounded in analytical foundations shared by economics, psychology, philosophy, and management science. Those foundations provide a framework for accommodating affective and social factors that shape and complement the cognitive processes of decision making. The decision sciences have grown through applications requiring collaboration with subject matter experts, familiar with the substance of the choices and the opportunities for interventions. Over the past half century, the field has shifted its emphasis from predicting choices, which can be successful without theoretical insight, to understanding the processes shaping them. Those processes are often revealed through biases that suggest non-normative processes. The practical importance of these biases depends on the sensitivity of specific decisions and the support that individuals have in making them. As a result, the field offers no simple summary of individuals' competence as decision makers, but a suite of theories and methods suited to capturing these sensitivities. Copyright © 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website. Copyright © 2010 John Wiley & Sons, Ltd.
Quality factor concept in piezoceramic transformer performance description.
Mezheritsky, Alex V
2006-02-01
A new general approach based on the quality factor concept to piezoceramic transformer (PT) performance description is proposed. The system's quality factor, material elastic anisotropy, and coupling factors of the input and output sections of an electrically excited and electrically loaded PT fully characterize its resonance and near-resonance behavior. The PT efficiency, transformation ratio, and input and output power were analytically analyzed and simulated as functions of the load and frequency for the simplest classical Langevin-type and Rosen-type PT designs. A new formulation of the electrical input impedance allows one to separate the power consumed by PT from the power transferred into the load. The system's PT quality factor takes into account losses in each PT "input-output-load" functional components. The loading process is changing PT input electrical impedance on the way that under loading the minimum series impedance is increasing and the maximum parallel impedance is decreasing coincidentally. The quality-factors ratio, between the states of fully loaded and nonloaded PT, is one of the best measures of PTs dynamic performance--practically, the lower the ratio is, the better PT efficiency. A simple and effective method for the loaded PT quality factor determination is proposed. As was found, a piezoceramic with low piezoelectric anisotropy is required to provide maximum PT efficiency and higher corresponding voltage gain. Limitations on the PT output voltage and power, caused by nonlinear effects in piezoceramics, were established.
Willis, Danny G; Sullivan-Bolyai, Susan; Knafl, Kathleen; Cohen, Marlene Z
2016-09-01
Scholars who research phenomena of concern to the discipline of nursing are challenged with making wise choices about different qualitative research approaches. Ultimately, they want to choose an approach that is best suited to answer their research questions. Such choices are predicated on having made distinctions between qualitative methodology, methods, and analytic frames. In this article, we distinguish two qualitative research approaches widely used for descriptive studies: descriptive phenomenological and qualitative description. Providing a clear basis that highlights the distinguishing features and similarities between descriptive phenomenological and qualitative description research will help students and researchers make more informed choices in deciding upon the most appropriate methodology in qualitative research. We orient the reader to distinguishing features and similarities associated with each approach and the kinds of research questions descriptive phenomenological and qualitative description research address. © The Author(s) 2016.
USDA-ARS?s Scientific Manuscript database
Current methods for generating malting quality metrics have been developed largely to support commercial malting and brewing operations, providing accurate, reproducible analytical data to guide malting and brewing production. Infrastructure to support these analytical operations often involves sub...
Analytical evaluation of current starch methods used in the international sugar industry: Part I
USDA-ARS?s Scientific Manuscript database
Several analytical starch methods currently exist in the international sugar industry that are used to prevent or mitigate starch-related processing challenges as well as assess the quality of traded end-products. These methods use simple iodometric chemistry, mostly potato starch standards, and uti...
On the Lowest Ro-Vibrational States of Protonated Methane: Experiment and Analytical Model
NASA Astrophysics Data System (ADS)
Schmiedt, Hanno; Jensen, Per; Asvany, Oskar; Schlemmer, Stephan
2016-06-01
Protonated methane, CH_5^+, is the prototype of an extremely floppy molecule. To the best of our knowledge all barriers are surmountable in the rovibrational ground state; the large amount of zero-point vibrational energy leads to large amplitude motions for many degrees of freedom. Low resolution but broad band vibrational spectroscopy [1] revealed an extremely wide range of C-H stretching vibrations. Comparison with theoretical IR spectra supported the structural motif of a CH_3 tripod and an H_2 moiety, bound to the central carbon atom by a 3c2e bond. In a more dynamic picture the five protons surround the central carbon atom without significant restrictions on the H-C-H bending or H_n-C torsional motions. The large-amplitude internal motions preclude a simple theoretical description of the type possible for more conventional molecules, such as the related spherical-top methane molecule. Recent high-resolution ro-vibrational spectra obtained in cold ion trap experiments [2] show that the observed CH_5^+ transitions belong to a very well-defined energy level scheme describing the lowest rotational and vibrational states of this enigmatic molecule. Here we analyse the experimental ground state combination differences and associate them with the motional states of CH_5^+ allowed by Fermi-Dirac statistics. A model Hamiltonian for unrestricted internal rotations in CH_5^+ yields a simple analytical expression for the energy eigenvalues, expressed in terms of new quantum numbers describing the free internal rotation. These results are compared to the experimental combination differences and the validity of the model will be discussed together with the underlying assumptions. [1] O. Asvany, P. Kumar, I. Hegemann, B. Redlich, S. Schlemmer and D. Marx, Science 309, (2005) 1219-1222 [2] O. Asvany, K.M.T. Yamada, S. Brünken, A. Potapov, S. Schlemmer, Science 347 (2015) 1346-1349
Diagnostic reasoning by hospital pharmacists: assessment of attitudes, knowledge, and skills.
Chernushkin, Kseniya; Loewen, Peter; de Lemos, Jane; Aulakh, Amneet; Jung, Joanne; Dahri, Karen
2012-07-01
Hospital pharmacists participate in activities that may be considered diagnostic. Two reasoning approaches to diagnosis have been described: non-analytic and analytic. Of the 6 analytic traditions, the probabilistic tradition has been shown to improve diagnostic accuracy and reduce unnecessary testing. To the authors' knowledge, pharmacists' attitudes toward having a diagnostic role and their diagnostic knowledge and skills have never been studied. To describe pharmacists' attitudes toward the role of diagnosis in pharmacotherapeutic problem-solving and to characterize the extent of pharmacists' knowledge and skills related to diagnostic literacy. Pharmacists working within Lower Mainland Pharmacy Services (British Columbia) who spent at least 33% of their time in direct patient care were invited to participate in a prospective observational survey. The survey sought information about demographic characteristics and attitudes toward diagnosis. Diagnostic knowledge and skills were tested by means of 3 case scenarios. The analysis included simple descriptive statistics and inferential statistics to evaluate relationships between responses and experience and training. Of 266 pharmacists invited to participate, 94 responded. The attitudes section of the survey was completed by 90 pharmacists; of these, 80 (89%) agreed with the definition of "diagnosis" proposed in the survey, and 83 (92%) agreed that it is important for pharmacists to have diagnosis-related skills. Respondents preferred an analytic to a non-analytic approach to diagnostic decision-making. The probabilistic tradition was not the preferred method in any of the 3 cases. In evaluating 5 clinical scenarios that might require diagnostic skills, on average 84% of respondents agreed that they should be involved in assessing such problems. Respondents' knowledge of and ability to apply probabilistic diagnostic tools were highest for test sensitivity (average of 61% of respondents with the correct answers) and lower for test specificity (average of 48% with correct answers) and likelihood ratios (average of 39% with correct answers). Respondents to this survey strongly believed that diagnostic skills were important for solving drug-related problems, but they demonstrated low levels of knowledge and ability to apply concepts of probabilistic diagnostic reasoning. Opportunities to expand pharmacists' knowledge of diagnostic reasoning exist, and the findings reported here indicate that pharmacists would consider such professional development valuable.
Rohr, Lana; Abdel Rahman, Rasha
2018-07-01
Humans have a unique capacity to induce intense emotional states in others by simple acts of verbal communication, and simple messages such as bad can elicit strong emotions in the addressee. However, up to now, research has mainly focused on general emotional meaning aspects and paradigms of low personal relevance (e.g., word reading), thereby possibly underestimating the impact of verbal emotion. In the present study, we recorded ERPs while presenting emotional words differing in word-inherent person descriptiveness (in that they may or may not refer to or describe a person; e.g., winner vs. sunflower). We predicted stronger emotional responses to person-descriptive words. Additionally, we enhanced the relevance of the words by embedding them in social-communicative contexts. We observed strong parallels in the characteristics of emotion and descriptiveness effects, suggesting a common underlying motivational basis. Furthermore, word-inherent person descriptiveness affected emotion processing at late elaborate stages reflected in the late positive potential, with emotion effects found only for descriptive words. The present findings underline the importance of factors determining the personal relevance of emotional words. © 2018 Society for Psychophysiological Research.
ERIC Educational Resources Information Center
Scott, Patrick B., Ed.
1991-01-01
REDUC is a cooperative network of some 23 associated centers in 17 Latin American and Caribbean countries. The REDUC coordinating center is located in Santiago, Chile. REDUC produces a bibliographic database containing analytical summaries (approximately 800 items annually) of the most important research studies and project descriptions in the…
A SIMPLE, EFFICIENT SOLUTION OF FLUX-PROFILE RELATIONSHIPS IN THE ATMOSPHERIC SURFACE LAYER
This note describes a simple scheme for analytical estimation of the surface layer similarity functions from state variables. What distinguishes this note from the many previous papers on this topic is that this method is specifically targeted for numerical models where simplici...
NASA Astrophysics Data System (ADS)
Kallinikos, N.; Isliker, H.; Vlahos, L.; Meletlidou, E.
2014-06-01
An analytical description of magnetic islands is presented for the typical case of a single perturbation mode introduced to tokamak plasma equilibrium in the large aspect ratio approximation. Following the Hamiltonian structure directly in terms of toroidal coordinates, the well known integrability of this system is exploited, laying out a precise and practical way for determining the island topology features, as required in various applications, through an analytical and exact flux surface label.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kallinikos, N.; Isliker, H.; Vlahos, L.
2014-06-15
An analytical description of magnetic islands is presented for the typical case of a single perturbation mode introduced to tokamak plasma equilibrium in the large aspect ratio approximation. Following the Hamiltonian structure directly in terms of toroidal coordinates, the well known integrability of this system is exploited, laying out a precise and practical way for determining the island topology features, as required in various applications, through an analytical and exact flux surface label.
Parametrizing growth in dark energy and modified gravity models
NASA Astrophysics Data System (ADS)
Resco, Miguel Aparicio; Maroto, Antonio L.
2018-02-01
It is well known that an extremely accurate parametrization of the growth function of matter density perturbations in Λ CDM cosmology, with errors below 0.25%, is given by f (a )=Ωmγ(a ) with γ ≃0.55 . In this work, we show that a simple modification of this expression also provides a good description of growth in modified gravity theories. We consider the model-independent approach to modified gravity in terms of an effective Newton constant written as μ (a ,k )=Geff/G and show that f (a )=β (a )Ωmγ(a ) provides fits to the numerical solutions with similar accuracy to that of Λ CDM . In the time-independent case with μ =μ (k ), simple analytic expressions for β (μ ) and γ (μ ) are presented. In the time-dependent (but scale-independent) case μ =μ (a ), we show that β (a ) has the same time dependence as μ (a ). As an example, explicit formulas are provided in the Dvali-Gabadadze-Porrati (DGP) model. In the general case, for theories with μ (a ,k ), we obtain a perturbative expansion for β (μ ) around the general relativity case μ =1 which, for f (R ) theories, reaches an accuracy below 1%. Finally, as an example we apply the obtained fitting functions in order to forecast the precision with which future galaxy surveys will be able to measure the μ parameter.
Dixon, Lance J.; Luo, Ming-xing; Shtabovenko, Vladyslav; ...
2018-03-09
Here, the energy-energy correlation (EEC) between two detectors in e +e – annihilation was computed analytically at leading order in QCD almost 40 years ago, and numerically at next-to-leading order (NLO) starting in the 1980s. We present the first analytical result for the EEC at NLO, which is remarkably simple, and facilitates analytical study of the perturbative structure of the EEC. We provide the expansion of the EEC in the collinear and back-to-back regions through next-to-leading power, information which should aid resummation in these regions.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dixon, Lance J.; Luo, Ming-xing; Shtabovenko, Vladyslav
Here, the energy-energy correlation (EEC) between two detectors in e +e – annihilation was computed analytically at leading order in QCD almost 40 years ago, and numerically at next-to-leading order (NLO) starting in the 1980s. We present the first analytical result for the EEC at NLO, which is remarkably simple, and facilitates analytical study of the perturbative structure of the EEC. We provide the expansion of the EEC in the collinear and back-to-back regions through next-to-leading power, information which should aid resummation in these regions.
School Behind Bars--A Descriptive Overview of Correctional Education in the American Prison System.
ERIC Educational Resources Information Center
Syracuse Univ. Research Corp., NY. Policy Inst.
This report, intended to be a descriptive yet analytical overview of correctional education programs, is organized into six chapters. Chapter one discusses the philosophical aspects (pro and con) of prisoner education. Chapter two traces the history of prisoner education from the roots of its beginning to the present. Chapter three presents the…
Stojanowski, Christopher M; Buikstra, Jane E
2005-09-01
This paper explores recent research trends in human osteology, based on articles published in the American Journal of Physical Anthropology (AJPA) during two 5-year intervals: 1980--1984 and 1996--2000. Topical "visibility" is measured in terms of article counts; "impact" is estimated through citation indices. Our results indicate that human osteologists continue to publish a range of methodological, analytical, and descriptive research papers that address a broad array of subjects. Analytical articles are cited more frequently than descriptive articles and thus have higher impact, reflecting the discipline's continued commitment to problem-oriented research. Differences in publication patterns exist between scholars during early and later stages of their careers. Articles published by students and Ph.D.s within 2 years of their doctoral degree are more frequently descriptive than analytical, when compared to people with longer career histories. Topics such as pathology, forensic anthropology, and biodistance modeling remain highly visible, while articles on the dentition have waned. An increase in functional research directed toward the postcranial skeleton is also reflected in our data. While continued visibility for morphological investigations is apparent, the impact of recently developed applications in bone chemistry and molecular anthropology is amply documented in our data, particularly during the more recent survey years. (c) 2005 Wiley-Liss, Inc.
NASA Astrophysics Data System (ADS)
Bisegna, Paolo; Caselli, Federica
2008-06-01
This paper presents a simple analytical expression for the effective complex conductivity of a periodic hexagonal arrangement of conductive circular cylinders embedded in a conductive matrix, with interfaces exhibiting a capacitive impedance. This composite material may be regarded as an idealized model of a biological tissue comprising tubular cells, such as skeletal muscle. The asymptotic homogenization method is adopted, and the corresponding local problem is solved by resorting to Weierstrass elliptic functions. The effectiveness of the present analytical result is proved by convergence analysis and comparison with finite-element solutions and existing models.
[A new model fo the evaluation of measurements of the neurocranium].
Seidler, H; Wilfing, H; Weber, G; Traindl-Prohazka, M; zur Nedden, D; Platzer, W
1993-12-01
A simple and user-friendly model for trigonometric description of the neurocranium based on newly defined points of measurement is presented. This model not only provides individual description, but also allows for an evaluation of developmental and phylogenetic aspects.
From Complex to Simple: Interdisciplinary Stochastic Models
ERIC Educational Resources Information Center
Mazilu, D. A.; Zamora, G.; Mazilu, I.
2012-01-01
We present two simple, one-dimensional, stochastic models that lead to a qualitative understanding of very complex systems from biology, nanoscience and social sciences. The first model explains the complicated dynamics of microtubules, stochastic cellular highways. Using the theory of random walks in one dimension, we find analytical expressions…
The path of a click stimulus from ear canal to umbo.
Milazzo, Mario; Fallah, Elika; Carapezza, Michael; Kumar, Nina S; Lei, Jason H; Olson, Elizabeth S
2017-03-01
The tympanic membrane (TM) has a key role in transmitting sounds to the inner ear, but a concise description of how the TM performs this function remains elusive. This paper probes TM operation by applying a free field click stimulus to the gerbil ear and exploring the consequent motions of the TM and umbo. Motions of the TM were measured both on radial tracks starting close to the umbo and on a grid distal and adjacent to the umbo. The experimental results confirmed the high fidelity of sound transmission from the ear canal to the umbo. A delay of 5-15 μs was seen in the onset of TM motion between points just adjacent to the umbo and mid-radial points. The TM responded with a ringing motion, with different locations possessing different primary ringing frequencies. A simple analytic model from the literature, treating the TM as a string, was used to explore the experimental results. The click-based experiments and analysis led to the following description of TM operation: A transient sound pressure on the TM causes a transient initial TM motion that is maximal ∼ at the TM's radial midpoints. Mechanical forces generated by this initial prominent TM distortion then pull the umbo inward, leading to a delayed umbo response. The initial TM deformation also gives rise to prolonged mechanical ringing on the TM that does not result in significant umbo motion, likely due to destructive interference from the range of ringing frequencies. Thus, the umbo's response is a high-fidelity representation of the transient stimulus. Because any sound can be considered as a consecutive series of clicks, this description is applicable to any sound stimulus. Copyright © 2017 Elsevier B.V. All rights reserved.
The path of a click stimulus from earcanal to umbo
Milazzo, Mario; Fallah, Elika; Carapezza, Michael; Kumar, Nina S.; Lei, Jason H.; Olson, Elizabeth S.
2017-01-01
The tympanic membrane (TM) has a key role in transmitting sounds to the inner ear, but a concise description of how the TM performs this function remains elusive. This paper probes TM operation by applying a free field click stimulus to the gerbil ear and exploring the consequent motions of the TM and umbo. Motions of the TM were measured both on radial tracks starting close to the umbo and on a grid distal and adjacent to the umbo. The experimental results confirmed the high fidelity of sound transmission from the ear canal to the umbo. A delay of 5 – 15 μs was seen in the onset of TM motion between points just adjacent to the umbo and mid-radial points. The TM responded with a ringing motion, with different locations possessing different primary ringing frequencies. A simple analytic model from the literature, treating the TM as a string, was used to explore the experimental results. The click-based experiments and analysis led to the following description of TM operation: A transient sound pressure on the TM causes a transient initial TM motion that is maximal ~ at the TM’s radial midpoints. Mechanical forces generated by this initial prominent TM distortion then pull the umbo inward, leading to a delayed umbo response. The initial TM deformation also gives rise to prolonged mechanical ringing on the TM that does not result in significant umbo motion, likely due to destructive interference from the range of ringing frequencies. Thus, the umbo’s response is a high-fidelity representation of the transient stimulus. Because any sound can be considered as a consecutive series of clicks, this description is applicable to any sound stimulus. PMID:28087416
A simple analytical thermo-mechanical model for liquid crystal elastomer bilayer structures
NASA Astrophysics Data System (ADS)
Cui, Yun; Wang, Chengjun; Sim, Kyoseung; Chen, Jin; Li, Yuhang; Xing, Yufeng; Yu, Cunjiang; Song, Jizhou
2018-02-01
The bilayer structure consisting of thermal-responsive liquid crystal elastomers (LCEs) and other polymer materials with stretchable heaters has attracted much attention in applications of soft actuators and soft robots due to its ability to generate large deformations when subjected to heat stimuli. A simple analytical thermo-mechanical model, accounting for the non-uniform feature of the temperature/strain distribution along the thickness direction, is established for this type of bilayer structure. The analytical predictions of the temperature and bending curvature radius agree well with finite element analysis and experiments. The influences of the LCE thickness and the heat generation power on the bending deformation of the bilayer structure are fully investigated. It is shown that a thinner LCE layer and a higher heat generation power could yield more bending deformation. These results may help the design of soft actuators and soft robots involving thermal responsive LCEs.
Using Presentation Software to Flip an Undergraduate Analytical Chemistry Course
ERIC Educational Resources Information Center
Fitzgerald, Neil; Li, Luisa
2015-01-01
An undergraduate analytical chemistry course has been adapted to a flipped course format. Course content was provided by video clips, text, graphics, audio, and simple animations organized as concept maps using the cloud-based presentation platform, Prezi. The advantages of using Prezi to present course content in a flipped course format are…
Data Acquisition Programming (LabVIEW): An Aid to Teaching Instrumental Analytical Chemistry.
ERIC Educational Resources Information Center
Gostowski, Rudy
A course was developed at Austin Peay State University (Tennessee) which offered an opportunity for hands-on experience with the essential components of modern analytical instruments. The course aimed to provide college students with the skills necessary to construct a simple model instrument, including the design and fabrication of electronic…
Operational Environmental Assessment
1988-09-01
Chemistry Branch - Physical Chemistry Branch " Analytical Research Division - Analytical Systems Branch - Methodology Research Branch - Spectroscopy Branch...electromagnetic frequency spec- trum and includes radio frequencies, infrared , visible light, ultraviolet, X-rays and gamma rays (in ascending order of...Verruculogen Aflatrem Picrotoxin Ciguatoxin Mycotoxins Simple Tr ichothecenes T-2 Toxin T-2 Tetraol Neosolaniol * Nivalenol Deoxynivalenol Verrucarol B-3 B lank
Numerical Simulation of the Perrin-Like Experiments
ERIC Educational Resources Information Center
Mazur, Zygmunt; Grech, Dariusz
2008-01-01
A simple model of the random Brownian walk of a spherical mesoscopic particle in viscous liquids is proposed. The model can be solved analytically and simulated numerically. The analytic solution gives the known Einstein-Smoluchowski diffusion law r[superscript 2] = 2Dt, where the diffusion constant D is expressed by the mass and geometry of a…
ERIC Educational Resources Information Center
Lavilla, Isela; Costas, Marta; Pena-Pereira, Francisco; Gil, Sandra; Bendicho, Carlos
2011-01-01
Ultrasound-assisted extraction (UAE) is introduced to upper-level analytical chemistry students as a simple strategy focused on sample preparation for trace-metal determination in biological tissues. Nickel extraction in seafood samples and quantification by electrothermal atomic absorption spectrometry (ETAAS) are carried out by a team of four…
NASA Astrophysics Data System (ADS)
Ke, Xinyou; Alexander, J. Iwan D.; Prahl, Joseph M.; Savinell, Robert F.
2015-08-01
A simple analytical model of a layered system comprised of a single passage of a serpentine flow channel and a parallel underlying porous electrode (or porous layer) is proposed. This analytical model is derived from Navier-Stokes motion in the flow channel and Darcy-Brinkman model in the porous layer. The continuities of flow velocity and normal stress are applied at the interface between the flow channel and the porous layer. The effects of the inlet volumetric flow rate, thickness of the flow channel and thickness of a typical carbon fiber paper porous layer on the volumetric flow rate within this porous layer are studied. The maximum current density based on the electrolyte volumetric flow rate is predicted, and found to be consistent with reported numerical simulation. It is found that, for a mean inlet flow velocity of 33.3 cm s-1, the analytical maximum current density is estimated to be 377 mA cm-2, which compares favorably with experimental result reported by others of ∼400 mA cm-2.
NASA Astrophysics Data System (ADS)
Patil, S. H.; Tang, K. T.; Toennies, J. P.
1999-10-01
Simple analytical wave functions satisfying appropriate boundary conditions are constructed for the ground states of one-and two-electron homonuclear molecules. Both the asymptotic condition when one electron is far away and the cusp condition when the electron coalesces with a nucleus are satisfied by the proposed wave function. For H2+, the resulting wave function is almost identical to the Guillemin-Zener wave function which is known to give very good energies. For the two electron systems H2 and He2++, the additional electron-electron cusp condition is rigorously accounted for by a simple analytic correlation function which has the correct behavior not only for r12→0 and r12→∞ but also for R→0 and R→∞, where r12 is the interelectronic distance and R, the internuclear distance. Energies obtained from these simple wave functions agree within 2×10-3 a.u. with the results of the most sophisticated variational calculations for all R and for all systems studied. This demonstrates that rather simple physical considerations can be used to derive very accurate wave functions for simple molecules thereby avoiding laborious numerical variational calculations.
Ayela, Cédric; Dubourg, Georges; Pellet, Claude; Haupt, Karsten
2014-09-03
Cantilever-type all-organic microelectromechanical systems based on molecularly imprinted polymers for specific analyte recognition are used as chemical sensors. They are produced by a simple spray-coating-shadow-masking process. Analyte binding to the cantilever generates a measurable change in its resonance frequency. This allows label-free detection by direct mass sensing of low-molecular-weight analytes at nanomolar concentrations. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Cohen, Noa; Sabhachandani, Pooja; Golberg, Alexander; Konry, Tania
2015-04-15
In this study we describe a simple lab-on-a-chip (LOC) biosensor approach utilizing well mixed microfluidic device and a microsphere-based assay capable of performing near real-time diagnostics of clinically relevant analytes such cytokines and antibodies. We were able to overcome the adsorption kinetics reaction rate-limiting mechanism, which is diffusion-controlled in standard immunoassays, by introducing the microsphere-based assay into well-mixed yet simple microfluidic device with turbulent flow profiles in the reaction regions. The integrated microsphere-based LOC device performs dynamic detection of the analyte in minimal amount of biological specimen by continuously sampling micro-liter volumes of sample per minute to detect dynamic changes in target analyte concentration. Furthermore we developed a mathematical model for the well-mixed reaction to describe the near real time detection mechanism observed in the developed LOC method. To demonstrate the specificity and sensitivity of the developed real time monitoring LOC approach, we applied the device for clinically relevant analytes: Tumor Necrosis Factor (TNF)-α cytokine and its clinically used inhibitor, anti-TNF-α antibody. Based on the reported results herein, the developed LOC device provides continuous sensitive and specific near real-time monitoring method for analytes such as cytokines and antibodies, reduces reagent volumes by nearly three orders of magnitude as well as eliminates the washing steps required by standard immunoassays. Copyright © 2014 Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Martin, Florence; Ndoye, Abdou; Wilkins, Patricia
2016-01-01
Quality Matters is recognized as a rigorous set of standards that guide the designer or instructor to design quality online courses. We explore how Quality Matters standards guide the identification and analysis of learning analytics data to monitor and improve online learning. Descriptive data were collected for frequency of use, time spent, and…
Spectral properties of thermal fluctuations on simple liquid surfaces below shot-noise levels.
Aoki, Kenichiro; Mitsui, Takahisa
2012-07-01
We study the spectral properties of thermal fluctuations on simple liquid surfaces, sometimes called ripplons. Analytical properties of the spectral function are investigated and are shown to be composed of regions with simple analytic behavior with respect to the frequency or the wave number. The derived expressions are compared to spectral measurements performed orders of magnitude below shot-noise levels, which is achieved using a novel noise reduction method. The agreement between the theory of thermal surface fluctuations and the experiment is found to be excellent, elucidating the spectral properties of the surface fluctuations. The measurement method requires relatively only a small sample both spatially (few μm) and temporally (~20 s). The method also requires relatively weak light power (~0.5 mW) so that it has a broad range of applicability, including local measurements, investigations of time-dependent phenomena, and noninvasive measurements.
Experimental evaluation of expendable supersonic nozzle concepts
NASA Technical Reports Server (NTRS)
Baker, V.; Kwon, O.; Vittal, B.; Berrier, B.; Re, R.
1990-01-01
Exhaust nozzles for expendable supersonic turbojet engine missile propulsion systems are required to be simple, short and compact, in addition to having good broad-range thrust-minus-drag performance. A series of convergent-divergent nozzle scale model configurations were designed and wind tunnel tested for a wide range of free stream Mach numbers and nozzle pressure ratios. The models included fixed geometry and simple variable exit area concepts. The experimental and analytical results show that the fixed geometry configurations tested have inferior off-design thrust-minus-drag performance in the transonic Mach range. A simple variable exit area configuration called the Axi-Quad nozzle, combining features of both axisymmetric and two-dimensional convergent-divergent nozzles, performed well over a broad range of operating conditions. Analytical predictions of the flow pattern as well as overall performance of the nozzles, using a fully viscous, compressible CFD code, compared very well with the test data.
Analytical Computation of Energy-Energy Correlation at Next-to-Leading Order in QCD
NASA Astrophysics Data System (ADS)
Dixon, Lance J.; Luo, Ming-xing; Shtabovenko, Vladyslav; Yang, Tong-Zhi; Zhu, Hua Xing
2018-03-01
The energy-energy correlation (EEC) between two detectors in e+e- annihilation was computed analytically at leading order in QCD almost 40 years ago, and numerically at next-to-leading order (NLO) starting in the 1980s. We present the first analytical result for the EEC at NLO, which is remarkably simple, and facilitates analytical study of the perturbative structure of the EEC. We provide the expansion of the EEC in the collinear and back-to-back regions through next-to-leading power, information which should aid resummation in these regions.
van de Geijn, J; Fraass, B A
1984-01-01
The net fractional depth dose (NFD) is defined as the fractional depth dose (FDD) corrected for inverse square law. Analysis of its behavior as a function of depth, field size, and source-surface distance has led to an analytical description with only seven model parameters related to straightforward physical properties. The determination of the characteristic parameter values requires only seven experimentally determined FDDs. The validity of the description has been tested for beam qualities ranging from 60Co gamma rays to 18-MV x rays, using published data from several different sources as well as locally measured data sets. The small number of model parameters is attractive for computer or hand-held calculator applications. The small amount of required measured data is important in view of practical data acquisition for implementation of a computer-based dose calculation system. The generating function allows easy and accurate generation of FDD, tissue-air ratio, tissue-maximum ratio, and tissue-phantom ratio tables.
Net fractional depth dose: a basis for a unified analytical description of FDD, TAR, TMR, and TPR
DOE Office of Scientific and Technical Information (OSTI.GOV)
van de Geijn, J.; Fraass, B.A.
The net fractional depth dose (NFD) is defined as the fractional depth dose (FDD) corrected for inverse square law. Analysis of its behavior as a function of depth, field size, and source-surface distance has led to an analytical description with only seven model parameters related to straightforward physical properties. The determination of the characteristic parameter values requires only seven experimentally determined FDDs. The validity of the description has been tested for beam qualities ranging from /sup 60/Co gamma rays to 18-MV x rays, using published data from several different sources as well as locally measured data sets. The small numbermore » of model parameters is attractive for computer or hand-held calculator applications. The small amount of required measured data is important in view of practical data acquisition for implementation of a computer-based dose calculation system. The generating function allows easy and accurate generation of FDD, tissue-air ratio, tissue-maximum ratio, and tissue-phantom ratio tables.« less
NASA Astrophysics Data System (ADS)
Nenashev, A. V.; Koshkarev, A. A.; Dvurechenskii, A. V.
2018-03-01
We suggest an approach to the analytical calculation of the strain distribution due to an inclusion in elastically anisotropic media for the case of cubic anisotropy. The idea consists in the approximate reduction of the anisotropic problem to a (simpler) isotropic problem. This gives, for typical semiconductors, an improvement in accuracy by an order of magnitude, compared to the isotropic approximation. Our method allows using, in the case of elastically anisotropic media, analytical solutions obtained for isotropic media only, such as analytical formulas for the strain due to polyhedral inclusions. The present work substantially extends the applicability of analytical results, making them more suitable for describing real systems, such as epitaxial quantum dots.
ICDA: A Platform for Intelligent Care Delivery Analytics
Gotz, David; Stavropoulos, Harry; Sun, Jimeng; Wang, Fei
2012-01-01
The identification of high-risk patients is a critical component in improving patient outcomes and managing costs. This paper describes the Intelligent Care Delivery Analytics platform (ICDA), a system which enables risk assessment analytics that process large collections of dynamic electronic medical data to identify at-risk patients. ICDA works by ingesting large volumes of data into a common data model, then orchestrating a collection of analytics that identify at-risk patients. It also provides an interactive environment through which users can access and review the analytics results. In addition, ICDA provides APIs via which analytics results can be retrieved to surface in external applications. A detailed review of ICDA’s architecture is provided. Descriptions of four use cases are included to illustrate ICDA’s application within two different data environments. These use cases showcase the system’s flexibility and exemplify the types of analytics it enables. PMID:23304296
3-D discrete analytical ridgelet transform.
Helbert, David; Carré, Philippe; Andres, Eric
2006-12-01
In this paper, we propose an implementation of the 3-D Ridgelet transform: the 3-D discrete analytical Ridgelet transform (3-D DART). This transform uses the Fourier strategy for the computation of the associated 3-D discrete Radon transform. The innovative step is the definition of a discrete 3-D transform with the discrete analytical geometry theory by the construction of 3-D discrete analytical lines in the Fourier domain. We propose two types of 3-D discrete lines: 3-D discrete radial lines going through the origin defined from their orthogonal projections and 3-D planes covered with 2-D discrete line segments. These discrete analytical lines have a parameter called arithmetical thickness, allowing us to define a 3-D DART adapted to a specific application. Indeed, the 3-D DART representation is not orthogonal, It is associated with a flexible redundancy factor. The 3-D DART has a very simple forward/inverse algorithm that provides an exact reconstruction without any iterative method. In order to illustrate the potentiality of this new discrete transform, we apply the 3-D DART and its extension to the Local-DART (with smooth windowing) to the denoising of 3-D image and color video. These experimental results show that the simple thresholding of the 3-D DART coefficients is efficient.
A computational method for optimizing fuel treatment locations
Mark A. Finney
2006-01-01
Modeling and experiments have suggested that spatial fuel treatment patterns can influence the movement of large fires. On simple theoretical landscapes consisting of two fuel types (treated and untreated) optimal patterns can be analytically derived that disrupt fire growth efficiently (i.e. with less area treated than random patterns). Although conceptually simple,...
NASA Astrophysics Data System (ADS)
Keshavarz-Motamed, Zahra
2015-11-01
Coarctation of the aorta (COA) is a congenital heart disease corresponding to a narrowing in the aorta. Cardiac catheterization is considered to be the reference standard for definitive evaluation of COA severity, based on the peak-to-peak trans-coarctation pressure gradient (PtoP TCPG) and instantaneous systolic value of trans-COA pressure gradient (TCPG). However, invasive cardiac catheterization may carry high risks given that undergoing multiple follow-up cardiac catheterizations in patients with COA is common. The objective of this study is to present an analytical description of the COA that estimates PtoP TCPG and TCPG without a need for high risk invasive data collection. Coupled Navier-Stokes and elastic deformation equations were solved analytically to estimate TCPG and PtoP TCPG. The results were validated against data measured in vitro (e.g., 90% COA: TCPG: root mean squared error (RMSE) = 3.93 mmHg; PtoP TCPG: RMSE = 7.9 mmHg). Moreover, the estimated PtoP TCPG resulted from the suggested analytical description was validated using clinical data in twenty patients with COA (maximum RMSE: 8.3 mmHg). Very good correlation and concordance were found between TCPG and PtoP TCPG obtained from the analytical formulation and in vitro and in vivo data. The suggested methodology can be considered as an alternative to cardiac catheterization and can help preventing its risks.
Transport of a decay chain in homogenous porous media: analytical solutions.
Bauer, P; Attinger, S; Kinzelbach, W
2001-06-01
With the aid of integral transforms, analytical solutions for the transport of a decay chain in homogenous porous media are derived. Unidirectional steady-state flow and radial steady-state flow in single and multiple porosity media are considered. At least in Laplace domain, all solutions can be written in closed analytical formulae. Partly, the solutions can also be inverted analytically. If not, analytical calculation of the steady-state concentration distributions, evaluation of temporal moments and numerical inversion are still possible. Formulae for several simple boundary conditions are given and visualized in this paper. The derived novel solutions are widely applicable and are very useful for the validation of numerical transport codes.
Revisiting liver anatomy and terminology of hepatectomies.
Bismuth, Henri
2013-03-01
Since the development of liver surgery, several descriptions of liver anatomical division and hepatectomies have been made, causing some confusion among surgeons. The initial anatomical description according to Couinaud is reviewed and corrected taking into account the descriptions made in the following decades. It seems that by reviewing the description of the different authors, a precise anatomical division of the liver may be achieved and a simple terminology of hepatectomies may be proposed. It is hoped that the proposal of this anatomical description and this terminology of hepatectomies may find a consensus among the liver surgical community from America, Asia, and Europe.
Exact analytic solution for non-linear density fluctuation in a ΛCDM universe
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yoo, Jaiyul; Gong, Jinn-Ouk, E-mail: jyoo@physik.uzh.ch, E-mail: jinn-ouk.gong@apctp.org
We derive the exact third-order analytic solution of the matter density fluctuation in the proper-time hypersurface in a ΛCDM universe, accounting for the explicit time-dependence and clarifying the relation to the initial condition. Furthermore, we compare our analytic solution to the previous calculation in the comoving gauge, and to the standard Newtonian perturbation theory by providing Fourier kernels for the relativistic effects. Our results provide an essential ingredient for a complete description of galaxy bias in the relativistic context.
NASA Technical Reports Server (NTRS)
Sadunas, J. A.; French, E. P.; Sexton, H.
1973-01-01
A 1/25 scale model S-2 stage base region thermal environment test is presented. Analytical results are included which reflect the effect of engine operating conditions, model scale, turbo-pump exhaust gas injection on base region thermal environment. Comparisons are made between full scale flight data, model test data, and analytical results. The report is prepared in two volumes. The description of analytical predictions and comparisons with flight data are presented. Tabulation of the test data is provided.
A Comprehensive Analytical Solution of the Nonlinear Pendulum
ERIC Educational Resources Information Center
Ochs, Karlheinz
2011-01-01
In this paper, an analytical solution for the differential equation of the simple but nonlinear pendulum is derived. This solution is valid for any time and is not limited to any special initial instance or initial values. Moreover, this solution holds if the pendulum swings over or not. The method of approach is based on Jacobi elliptic functions…
Peters, J.G.
1987-01-01
The Indiana Department of Natural Resources (IDNR) is developing water-management policies designed to assess the effects of irrigation and other water uses on water supply in the basin. In support of this effort, the USGS, in cooperation with IDNR, began a study to evaluate appropriate methods for analyzing the effects of pumping on ground-water levels and streamflow in the basin 's glacial aquifer systems. Four analytical models describe drawdown for a nonleaky, confined aquifer and fully penetrating well; a leaky, confined aquifer and fully penetrating well; a leaky, confined aquifer and partially penetrating well; and an unconfined aquifer and partially penetrating well. Analytical equations, simplifying assumptions, and methods of application are described for each model. In addition to these four models, several other analytical models were used to predict the effects of ground-water pumping on water levels in the aquifer and on streamflow in local areas with up to two pumping wells. Analytical models for a variety of other hydrogeologic conditions are cited. A digital ground-water flow model was used to describe how a numerical model can be applied to a glacial aquifer system. The numerical model was used to predict the effects of six pumping plans in 46.5 sq mi area with as many as 150 wells. Water budgets for the six pumping plans were used to estimate the effect of pumping on streamflow reduction. Results of the analytical and numerical models indicate that, in general, the glacial aquifers in the basin are highly permeable. Radial hydraulic conductivity calculated by the analytical models ranged from 280 to 600 ft/day, compared to 210 and 360 ft/day used in the numerical model. Maximum seasonal pumping for irrigation produced maximum calculated drawdown of only one-fourth of available drawdown and reduced streamflow by as much as 21%. Analytical models are useful in estimating aquifer properties and predicting local effects of pumping in areas with simple lithology and boundary conditions and with few pumping wells. Numerical models are useful in regional areas with complex hydrogeology with many pumping wells and provide detailed water budgets useful for estimating the sources of water in pumping simulations. Numerical models are useful in constructing flow nets. The choice of which type of model to use is also based on the nature and scope of questions to be answered and on the degree of accuracy required. (Author 's abstract)
Prodinger, Birgit; Reinhardt, Jan D; Selb, Melissa; Stucki, Gerold; Yan, Tiebin; Zhang, Xia; Li, Jianan
2016-06-13
A national, multi-phase, consensus process to develop simple, intuitive descriptions of International Classification of Functioning, Disability and Health (ICF) categories contained in the ICF Generic and Rehabilitation Sets, with the aim of enhancing the utility of the ICF in routine clinical practice, is presented in this study. A multi-stage, national, consensus process was conducted. The consensus process involved 3 expert groups and consisted of a preparatory phase, a consensus conference with consecutive working groups and 3 voting rounds (votes A, B and C), followed by an implementation phase. In the consensus conference, participants first voted on whether they agreed that an initially developed proposal for simple, intuitive descriptions of an ICF category was in fact simple and intuitive. The consensus conference was held in August 2014 in mainland China. Twenty-one people with a background in physical medicine and rehabilitation participated in the consensus process. Four ICF categories achieved consensus in vote A, 16 in vote B, and 8 in vote C. This process can be seen as part of a larger effort towards the system-wide implementation of the ICF in routine clinical and rehabilitation practice to allow for the regular and comprehensive evaluation of health outcomes most relevant for the monitoring of quality of care.
A Simple Sonication Improves Protein Signal in Matrix-Assisted Laser Desorption Ionization Imaging
NASA Astrophysics Data System (ADS)
Lin, Li-En; Su, Pin-Rui; Wu, Hsin-Yi; Hsu, Cheng-Chih
2018-02-01
Proper matrix application is crucial in obtaining high quality matrix-assisted laser desorption ionization (MALDI) mass spectrometry imaging (MSI). Solvent-free sublimation was essentially introduced as an approach of homogeneous coating that gives small crystal size of the organic matrix. However, sublimation has lower extraction efficiency of analytes. Here, we present that a simple sonication step after the hydration in standard sublimation protocol significantly enhances the sensitivity of MALDI MSI. This modified procedure uses a common laboratory ultrasonicator to immobilize the analytes from tissue sections without noticeable delocalization. Improved imaging quality with additional peaks above 10 kDa in the spectra was thus obtained upon sonication treatment. [Figure not available: see fulltext.
Merli, Daniele; Zamboni, Daniele; Protti, Stefano; Pesavento, Maria; Profumo, Antonella
2014-12-01
Lysergic acid diethylamide (LSD) is hardly detectable and quantifiable in biological samples because of its low active dose. Although several analytical tests are available, routine analysis of this drug is rarely performed. In this article, we report a simple and accurate method for the determination of LSD, based on adsorptive stripping voltammetry in DMF/tetrabutylammonium perchlorate, with a linear range of 1-90 ng L(-1) for deposition times of 50s. LOD of 1.4 ng L(-1) and LOQ of 4.3 ng L(-1) were found. The method can be also applied to biological samples after a simple extraction with 1-chlorobutane. Copyright © 2014 Elsevier B.V. All rights reserved.
Ground temperature measurement by PRT-5 for maps experiment
NASA Technical Reports Server (NTRS)
Gupta, S. K.; Tiwari, S. N.
1978-01-01
A simple algorithm and computer program were developed for determining the actual surface temperature from the effective brightness temperature as measured remotely by a radiation thermometer called PRT-5. This procedure allows the computation of atmospheric correction to the effective brightness temperature without performing detailed radiative transfer calculations. Model radiative transfer calculations were performed to compute atmospheric corrections for several values of the surface and atmospheric parameters individually and in combination. Polynomial regressions were performed between the magnitudes or deviations of these parameters and the corresponding computed corrections to establish simple analytical relations between them. Analytical relations were also developed to represent combined correction for simultaneous variation of parameters in terms of their individual corrections.
Collector modulation in high-voltage bipolar transistor in the saturation mode: Analytical approach
NASA Astrophysics Data System (ADS)
Dmitriev, A. P.; Gert, A. V.; Levinshtein, M. E.; Yuferev, V. S.
2018-04-01
A simple analytical model is developed, capable of replacing the numerical solution of a system of nonlinear partial differential equations by solving a simple algebraic equation when analyzing the collector resistance modulation of a bipolar transistor in the saturation mode. In this approach, the leakage of the base current into the emitter and the recombination of non-equilibrium carriers in the base are taken into account. The data obtained are in good agreement with the results of numerical calculations and make it possible to describe both the motion of the front of the minority carriers and the steady state distribution of minority carriers across the collector in the saturation mode.
Silva, Thalita G; de Araujo, William R; Muñoz, Rodrigo A A; Richter, Eduardo M; Santana, Mário H P; Coltro, Wendell K T; Paixão, Thiago R L C
2016-05-17
We report the development of a simple, portable, low-cost, high-throughput visual colorimetric paper-based analytical device for the detection of procaine in seized cocaine samples. The interference of most common cutting agents found in cocaine samples was verified, and a novel electrochemical approach was used for sample pretreatment in order to increase the selectivity. Under the optimized experimental conditions, a linear analytical curve was obtained for procaine concentrations ranging from 5 to 60 μmol L(-1), with a detection limit of 0.9 μmol L(-1). The accuracy of the proposed method was evaluated using seized cocaine samples and an addition and recovery protocol.
SU-FF-T-668: A Simple Algorithm for Range Modulation Wheel Design in Proton Therapy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nie, X; Nazaryan, Vahagn; Gueye, Paul
2009-06-01
Purpose: To develop a simple algorithm in designing the range modulation wheel to generate a very smooth Spread-Out Bragg peak (SOBP) for proton therapy.Method and Materials: A simple algorithm has been developed to generate the weight factors in corresponding pristine Bragg peaks which composed a smooth SOBP in proton therapy. We used a modified analytical Bragg peak function based on Monte Carol simulation tool-kits of Geant4 as pristine Bragg peaks input in our algorithm. A simple METLAB(R) Quad Program was introduced to optimize the cost function in our algorithm. Results: We found out that the existed analytical function of Braggmore » peak can't directly use as pristine Bragg peak dose-depth profile input file in optimization of the weight factors since this model didn't take into account of the scattering factors introducing from the range shifts in modifying the proton beam energies. We have done Geant4 simulations for proton energy of 63.4 MeV with a 1.08 cm SOBP for variation of pristine Bragg peaks which composed this SOBP and modified the existed analytical Bragg peak functions for their peak heights, ranges of R{sub 0}, and Gaussian energies {sigma}{sub E}. We found out that 19 pristine Bragg peaks are enough to achieve a flatness of 1.5% of SOBP which is the best flatness in the publications. Conclusion: This work develops a simple algorithm to generate the weight factors which is used to design a range modulation wheel to generate a smooth SOBP in protonradiation therapy. We have found out that a medium number of pristine Bragg peaks are enough to generate a SOBP with flatness less than 2%. It is potential to generate data base to store in the treatment plan to produce a clinic acceptable SOBP by using our simple algorithm.« less
Faculty Forum: The GRE Analytical Writing Test-- Description and Utilization
ERIC Educational Resources Information Center
Briihl, Deborah S.; Wasieleski, David T.
2007-01-01
The authors surveyed graduate programs to see how they use the Graduate Record Examination Analytic Writing (GRE-AW) Test. Only 35% of the graduate programs that responded use the GRE-AW test in their admission policy; of the programs not using it, most do not plan to do so. The programs using the GRE-AW rated it as medium or low in importance in…
ERIC Educational Resources Information Center
Monroy, Carlos; Rangel, Virginia Snodgrass; Whitaker, Reid
2014-01-01
In this paper, we discuss a scalable approach for integrating learning analytics into an online K-12 science curriculum. A description of the curriculum and the underlying pedagogical framework is followed by a discussion of the challenges to be tackled as part of this integration. We include examples of data visualization based on teacher usage…
Applying Descriptive Statistics to Teaching the Regional Classification of Climate.
ERIC Educational Resources Information Center
Lindquist, Peter S.; Hammel, Daniel J.
1998-01-01
Describes an exercise for college and high school students that relates descriptive statistics to the regional climatic classification. The exercise introduces students to simple calculations of central tendency and dispersion, the construction and interpretation of scatterplots, and the definition of climatic regions. Forces students to engage…
15 CFR 950.3 - National Climatic Center (NCC).
Code of Federal Regulations, 2014 CFR
2014-01-01
...; develops analytical and descriptive products to meet user requirements; and provides facilities for the... Meteorological Experiment meteorological data, Global Atmospheric Research Program basic data set, solar...
15 CFR 950.3 - National Climatic Center (NCC).
Code of Federal Regulations, 2012 CFR
2012-01-01
...; develops analytical and descriptive products to meet user requirements; and provides facilities for the... Meteorological Experiment meteorological data, Global Atmospheric Research Program basic data set, solar...
15 CFR 950.3 - National Climatic Center (NCC).
Code of Federal Regulations, 2010 CFR
2010-01-01
...; develops analytical and descriptive products to meet user requirements; and provides facilities for the... Meteorological Experiment meteorological data, Global Atmospheric Research Program basic data set, solar...
15 CFR 950.3 - National Climatic Center (NCC).
Code of Federal Regulations, 2013 CFR
2013-01-01
...; develops analytical and descriptive products to meet user requirements; and provides facilities for the... Meteorological Experiment meteorological data, Global Atmospheric Research Program basic data set, solar...
15 CFR 950.3 - National Climatic Center (NCC).
Code of Federal Regulations, 2011 CFR
2011-01-01
...; develops analytical and descriptive products to meet user requirements; and provides facilities for the... Meteorological Experiment meteorological data, Global Atmospheric Research Program basic data set, solar...
NASA Astrophysics Data System (ADS)
Bellan, Diego; Pignari, Sergio A.
2016-07-01
This work deals with the statistical characterization of real-time digital measurement of the amplitude of harmonics affected by frequency instability. In fact, in modern power systems both the presence of harmonics and frequency instability are well-known and widespread phenomena mainly due to nonlinear loads and distributed generation, respectively. As a result, real-time monitoring of voltage/current frequency spectra is of paramount importance as far as power quality issues are addressed. Within this framework, a key point is that in many cases real-time continuous monitoring prevents the application of sophisticated algorithms to extract all the information from the digitized waveforms because of the required computational burden. In those cases only simple evaluations such as peak search of discrete Fourier transform are implemented. It is well known, however, that a slight change in waveform frequency results in lack of sampling synchronism and uncertainty in amplitude estimate. Of course the impact of this phenomenon increases with the order of the harmonic to be measured. In this paper an approximate analytical approach is proposed in order to describe the statistical properties of the measured magnitude of harmonics affected by frequency instability. By providing a simplified description of the frequency behavior of the windows used against spectral leakage, analytical expressions for mean value, variance, cumulative distribution function, and probability density function of the measured harmonics magnitude are derived in closed form as functions of waveform frequency treated as a random variable.
Vieux, Florent; Dubois, Christophe; Allegre, Laëtitia; Mandon, Lionel; Ciantar, Laurent; Darmon, Nicole
2013-01-01
To assess the impact on food-related cost of meals to fulfill the new compulsory dietary standards for primary schools in France. A descriptive study assessed the relationship between the level of compliance with the standards of observed school meals and their food-related cost. An analytical study assessed the cost of series of meals published in professional journals, and complying or not with new dietary standards. The costs were based on prices actually paid for food used to prepare school meals. Food-related cost of meals. Parametric and nonparametric tests from a total of 42 and 120 series of 20 meals in the analytical and descriptive studies, respectively. The descriptive study indicated that meeting the standards was not related to cost. The analytical study showed that fulfilling the frequency guidelines increased the cost, whereas fulfilling the portion sizes criteria decreased it. Series of meals fully respecting the standards (ie, frequency and portion sizes) cost significantly less (-0.10 €/meal) than series not fulfilling them, because the standards recommend smaller portion sizes. Introducing portion sizes rules in dietary standards for school catering may help increase dietary quality without increasing the food cost of meals. Copyright © 2013 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.
Prison Radicalization: The New Extremist Training Grounds?
2007-09-01
distributing and collecting survey data , and the data analysis. The analytical methodology includes descriptive and inferential statistical methods, in... statistical analysis of the responses to identify significant correlations and relationships. B. SURVEY DATA COLLECTION To effectively access a...Q18, Q19, Q20, and Q21. Due to the exploratory nature of this small survey, data analyses were confined mostly to descriptive statistics and
Battaglia, Maurizio; Gottsmann, J.; Carbone, D.; Fernandez, J.
2008-01-01
Time-dependent gravimetric measurements can detect subsurface processes long before magma flow leads to earthquakes or other eruption precursors. The ability of gravity measurements to detect subsurface mass flow is greatly enhanced if gravity measurements are analyzed and modeled with ground-deformation data. Obtaining the maximum information from microgravity studies requires careful evaluation of the layout of network benchmarks, the gravity environmental signal, and the coupling between gravity changes and crustal deformation. When changes in the system under study are fast (hours to weeks), as in hydrothermal systems and restless volcanoes, continuous gravity observations at selected sites can help to capture many details of the dynamics of the intrusive sources. Despite the instrumental effects, mainly caused by atmospheric temperature, results from monitoring at Mt. Etna volcano show that continuous measurements are a powerful tool for monitoring and studying volcanoes.Several analytical and numerical mathematical models can beused to fit gravity and deformation data. Analytical models offer a closed-form description of the volcanic source. In principle, this allows one to readily infer the relative importance of the source parameters. In active volcanic sites such as Long Valley caldera (California, U.S.A.) and Campi Flegrei (Italy), careful use of analytical models and high-quality data sets has produced good results. However, the simplifications that make analytical models tractable might result in misleading volcanological inter-pretations, particularly when the real crust surrounding the source is far from the homogeneous/ isotropic assumption. Using numerical models allows consideration of more realistic descriptions of the sources and of the crust where they are located (e.g., vertical and lateral mechanical discontinuities, complex source geometries, and topography). Applications at Teide volcano (Tenerife) and Campi Flegrei demonstrate the importance of this more realistic description in gravity calculations. ?? 2008 Society of Exploration Geophysicists. All rights reserved.
Ghaniyoun, Aram; Shakeri, Khosro; Heidari, Mohammad
2017-09-01
Workers in social service professions are the first candidates for job burnout. The researchers believe this is due to daily exposure to stressful situations and lack of positive conditions in the workplace. It seems that psychological empowerment of staff can affect their job burnout. This study aimed to investigate the relationship between psychological empowerment and job burnout in operational staff of emergency center. This was a descriptive correlational study. A total of 1100 operational staff of emergency center were evaluated, and of which, 285 persons were selected by simple random sampling method. Data were collected using Spritzer's psychological empowerment and Maslach Burnout Inventory questionnaires. SPSS software, version 18, was used for data analysis along with descriptive analytical tests. The findings of this study revealed that the majority of units (46%) were in intermediate level in terms of empowerment. Similarly, the majority of cases had intermediate level (77.5%), and a minor percentage (8.4%) had low levels of job burnout. Based on Pearson's correlation test, there was a significant invert correlation between psychological empowerment and job burnout. This inverse and significant relationship was also observed between the four components of psychological empowerment (competence, self-determination, impact, and meaning) and job burnout. According to the results of the study, policy makers and health planners can take some measures in enhancing psychological empowerment to prevent problems associated with job burnout, by identifying stressors and strategies to deal with them.
Sine-Gordon equation and its application to tectonic stress transfer
NASA Astrophysics Data System (ADS)
Bykov, Victor G.
2014-07-01
An overview is given on remarkable progress that has been made in theoretical studies of solitons and other nonlinear wave patterns, excited during the deformation of fault block (fragmented) geological media. The models that are compliant with the classical and perturbed sine-Gordon equations have only been chosen. In these mathematical models, the rotation angle of blocks (fragments) and their translatory displacement of the medium are used as dynamic variables. A brief description of the known models and their geophysical and geodynamic applications is given. These models reproduce the kinematic and dynamic features of the traveling deformation front (kink, soliton) generated in the fragmented media. It is demonstrated that the sine-Gordon equation is applicable to the description of series of the observed seismic data, modeling of strain waves, as well as the features related to fault dynamics and the subduction slab, including slow earthquakes, periodicity of episodic tremor and slow slip (ETS) events, and migration pattern of tremors. The study shows that simple heuristic models and analytical and numerical computations can explain triggering of seismicity by transient processes, such as stress changes associated with solitary strain waves in crustal faults. The need to develop the above-mentioned new (nonlinear) mathematical models of the deformed fault and fragmented media was caused by the reason that it is impossible to explain a lot of the observed effects, particularly, slow redistribution and migration of stresses in the lithosphere, within the framework of the linear elasticity theory.
Genome Scale Modeling in Systems Biology: Algorithms and Resources
Najafi, Ali; Bidkhori, Gholamreza; Bozorgmehr, Joseph H.; Koch, Ina; Masoudi-Nejad, Ali
2014-01-01
In recent years, in silico studies and trial simulations have complemented experimental procedures. A model is a description of a system, and a system is any collection of interrelated objects; an object, moreover, is some elemental unit upon which observations can be made but whose internal structure either does not exist or is ignored. Therefore, any network analysis approach is critical for successful quantitative modeling of biological systems. This review highlights some of most popular and important modeling algorithms, tools, and emerging standards for representing, simulating and analyzing cellular networks in five sections. Also, we try to show these concepts by means of simple example and proper images and graphs. Overall, systems biology aims for a holistic description and understanding of biological processes by an integration of analytical experimental approaches along with synthetic computational models. In fact, biological networks have been developed as a platform for integrating information from high to low-throughput experiments for the analysis of biological systems. We provide an overview of all processes used in modeling and simulating biological networks in such a way that they can become easily understandable for researchers with both biological and mathematical backgrounds. Consequently, given the complexity of generated experimental data and cellular networks, it is no surprise that researchers have turned to computer simulation and the development of more theory-based approaches to augment and assist in the development of a fully quantitative understanding of cellular dynamics. PMID:24822031
Ghaniyoun, Aram; Shakeri, Khosro; Heidari, Mohammad
2017-01-01
Background: Workers in social service professions are the first candidates for job burnout. The researchers believe this is due to daily exposure to stressful situations and lack of positive conditions in the workplace. It seems that psychological empowerment of staff can affect their job burnout. This study aimed to investigate the relationship between psychological empowerment and job burnout in operational staff of emergency center. Methods: This was a descriptive correlational study. A total of 1100 operational staff of emergency center were evaluated, and of which, 285 persons were selected by simple random sampling method. Data were collected using Spritzer's psychological empowerment and Maslach Burnout Inventory questionnaires. SPSS software, version 18, was used for data analysis along with descriptive analytical tests. Results: The findings of this study revealed that the majority of units (46%) were in intermediate level in terms of empowerment. Similarly, the majority of cases had intermediate level (77.5%), and a minor percentage (8.4%) had low levels of job burnout. Based on Pearson's correlation test, there was a significant invert correlation between psychological empowerment and job burnout. This inverse and significant relationship was also observed between the four components of psychological empowerment (competence, self-determination, impact, and meaning) and job burnout. Conclusions: According to the results of the study, policy makers and health planners can take some measures in enhancing psychological empowerment to prevent problems associated with job burnout, by identifying stressors and strategies to deal with them. PMID:28970654
Vertical and pitching resonance of train cars moving over a series of simple beams
NASA Astrophysics Data System (ADS)
Yang, Y. B.; Yau, J. D.
2015-02-01
The resonant response, including both vertical and pitching motions, of an undamped sprung mass unit moving over a series of simple beams is studied by a semi-analytical approach. For a sprung mass that is very small compared with the beam, we first simplify the sprung mass as a constant moving force and obtain the response of the beam in closed form. With this, we then solve for the response of the sprung mass passing over a series of simple beams, and validate the solution by an independent finite element analysis. To evaluate the pitching resonance, we consider the cases of a two-axle model and a coach model traveling over rough rails supported by a series of simple beams. The resonance of a train car is characterized by the fact that its response continues to build up, as it travels over more and more beams. For train cars with long axle intervals, the vertical acceleration induced by pitching resonance dominates the peak response of the train traveling over a series of simple beams. The present semi-analytical study allows us to grasp the key parameters involved in the primary/sub-resonant responses. Other phenomena of resonance are also discussed in the exemplar study.
Gamage, K A A; Joyce, M J
2011-10-01
A novel analytical approach is described that accounts for self-shielding of γ radiation in decommissioning scenarios. The approach is developed with plutonium-239, cobalt-60 and caesium-137 as examples; stainless steel and concrete have been chosen as the media for cobalt-60 and caesium-137, respectively. The analytical methods have been compared MCNPX 2.6.0 simulations. A simple, linear correction factor relates the analytical results and the simulated estimates. This has the potential to greatly simplify the estimation of self-shielding effects in decommissioning activities. Copyright © 2011 Elsevier Ltd. All rights reserved.
Ultramicroelectrode Array Based Sensors: A Promising Analytical Tool for Environmental Monitoring
Orozco, Jahir; Fernández-Sánchez, César; Jiménez-Jorquera, Cecilia
2010-01-01
The particular analytical performance of ultramicroelectrode arrays (UMEAs) has attracted a high interest by the research community and has led to the development of a variety of electroanalytical applications. UMEA-based approaches have demonstrated to be powerful, simple, rapid and cost-effective analytical tools for environmental analysis compared to available conventional electrodes and standardised analytical techniques. An overview of the fabrication processes of UMEAs, their characterization and applications carried out by the Spanish scientific community is presented. A brief explanation of theoretical aspects that highlight their electrochemical behavior is also given. Finally, the applications of this transducer platform in the environmental field are discussed. PMID:22315551
Progressive Visual Analytics: User-Driven Visual Exploration of In-Progress Analytics.
Stolper, Charles D; Perer, Adam; Gotz, David
2014-12-01
As datasets grow and analytic algorithms become more complex, the typical workflow of analysts launching an analytic, waiting for it to complete, inspecting the results, and then re-Iaunching the computation with adjusted parameters is not realistic for many real-world tasks. This paper presents an alternative workflow, progressive visual analytics, which enables an analyst to inspect partial results of an algorithm as they become available and interact with the algorithm to prioritize subspaces of interest. Progressive visual analytics depends on adapting analytical algorithms to produce meaningful partial results and enable analyst intervention without sacrificing computational speed. The paradigm also depends on adapting information visualization techniques to incorporate the constantly refining results without overwhelming analysts and provide interactions to support an analyst directing the analytic. The contributions of this paper include: a description of the progressive visual analytics paradigm; design goals for both the algorithms and visualizations in progressive visual analytics systems; an example progressive visual analytics system (Progressive Insights) for analyzing common patterns in a collection of event sequences; and an evaluation of Progressive Insights and the progressive visual analytics paradigm by clinical researchers analyzing electronic medical records.
ERIC Educational Resources Information Center
Pardos, Zachary A.; Whyte, Anthony; Kao, Kevin
2016-01-01
In this paper, we address issues of transparency, modularity, and privacy with the introduction of an open source, web-based data repository and analysis tool tailored to the Massive Open Online Course community. The tool integrates data request/authorization and distribution workflow features as well as provides a simple analytics module upload…
Sample injection and electrophoretic separation on a simple laminated paper based analytical device.
Xu, Chunxiu; Zhong, Minghua; Cai, Longfei; Zheng, Qingyu; Zhang, Xiaojun
2016-02-01
We described a strategy to perform multistep operations on a simple laminated paper-based separation device by using electrokinetic flow to manipulate the fluids. A laminated crossed-channel paper-based separation device was fabricated by cutting a filter paper sheet followed by lamination. Multiple function units including sample loading, sample injection, and electrophoretic separation were integrated on a single paper based analytical device for the first time, by applying potential at different reservoirs for sample, sample waste, buffer, and buffer waste. As a proof-of-concept demonstration, mixed sample solution containing carmine and sunset yellow were loaded in the sampling channel, and then injected into separation channel followed by electrophoretic separation, by adjusting the potentials applied at the four terminals of sampling and separation channel. The effects of buffer pH, buffer concentration, channel width, and separation time on resolution of electrophoretic separation were studied. This strategy may be used to perform multistep operations such as reagent dilution, sample injection, mixing, reaction, and separation on a single microfluidic paper based analytical device, which is very attractive for building micro total analysis systems on microfluidic paper based analytical devices. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Review of Thawing Time Prediction Models Depending on Process Conditions and Product Characteristics
Kluza, Franciszek; Spiess, Walter E. L.; Kozłowicz, Katarzyna
2016-01-01
Summary Determining thawing times of frozen foods is a challenging problem as the thermophysical properties of the product change during thawing. A number of calculation models and solutions have been developed. The proposed solutions range from relatively simple analytical equations based on a number of assumptions to a group of empirical approaches that sometimes require complex calculations. In this paper analytical, empirical and graphical models are presented and critically reviewed. The conditions of solution, limitations and possible applications of the models are discussed. The graphical and semi--graphical models are derived from numerical methods. Using the numerical methods is not always possible as running calculations takes time, whereas the specialized software and equipment are not always cheap. For these reasons, the application of analytical-empirical models is more useful for engineering. It is demonstrated that there is no simple, accurate and feasible analytical method for thawing time prediction. Consequently, simplified methods are needed for thawing time estimation of agricultural and food products. The review reveals the need for further improvement of the existing solutions or development of new ones that will enable accurate determination of thawing time within a wide range of practical conditions of heat transfer during processing. PMID:27904387
Cabrera-Peralta, Jerónimo; Peña-Alvarez, Araceli
2018-05-01
A simple method for the simultaneous determination of personal care product ingredients: galaxolide, tonalide, oxybenzone, 4-methylbenzyliden camphor, padimate-o, 2-ethylhexyl methoxycinnamate, octocrylene, triclosan, and methyl triclosan in lettuce by ultrasound-assisted extraction combined with solid-phase microextraction followed by gas chromatography with mass spectrometry was developed. Lettuce was directly extracted by ultrasound-assisted extraction with methanol, this extract was combined with water, extracted by solid-phase microextraction in immersion mode, and analyzed by gas chromatography with mass spectrometry. Good linear relationships (25-250 ng/g, R 2 > 0.9702) and low detection limits (1.0-25 ng/g) were obtained for analytes along with acceptable precision for almost all analytes (RSDs < 20%). The validated method was applied for the determination of personal care product ingredients in commercial lettuce and lettuces grown in soil and irrigated with the analytes, identifying the target analytes in leaves and roots of the latter. This procedure is a miniaturized and environmentally friendly proposal which can be a useful tool for quality analysis in lettuce. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Space Trajectories Error Analysis (STEAP) Programs. Volume 1: Analytic manual, update
NASA Technical Reports Server (NTRS)
1971-01-01
Manual revisions are presented for the modified and expanded STEAP series. The STEAP 2 is composed of three independent but related programs: NOMAL for the generation of n-body nominal trajectories performing a number of deterministic guidance events; ERRAN for the linear error analysis and generalized covariance analysis along specific targeted trajectories; and SIMUL for testing the mathematical models used in the navigation and guidance process. The analytic manual provides general problem description, formulation, and solution and the detailed analysis of subroutines. The programmers' manual gives descriptions of the overall structure of the programs as well as the computational flow and analysis of the individual subroutines. The user's manual provides information on the input and output quantities of the programs. These are updates to N69-36472 and N69-36473.
NASA Astrophysics Data System (ADS)
Timpe, Nathalie F.; Stuch, Julia; Scholl, Marcus; Russek, Ulrich A.
2016-03-01
This contribution presents a phenomenological, analytical model for laser welding of polymers which is suited for a quick process quality estimation for the practitioner. Besides material properties of the polymer and processing parameters like welding pressure, feed rate and laser power the model is based on a simple few parameter description of the size and shape of the laser power density distribution (PDD) in the processing zone. The model allows an estimation of the weld seam tensile strength. It is based on energy balance considerations within a thin sheet with the thickness of the optical penetration depth on the surface of the absorbing welding partner. The joining process itself is modelled by a phenomenological approach. The model reproduces the experimentally known process windows for the main process parameters correctly. Using the parameters describing the shape of the laser PDD the critical dependence of the process windows on the PDD shape will be predicted and compared with experiments. The adaption of the model to other laser manufacturing processes where the PDD influence can be modelled comparably will be discussed.
Time Dependent Data Mining in RAVEN
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cogliati, Joshua Joseph; Chen, Jun; Patel, Japan Ketan
RAVEN is a generic software framework to perform parametric and probabilistic analysis based on the response of complex system codes. The goal of this type of analyses is to understand the response of such systems in particular with respect their probabilistic behavior, to understand their predictability and drivers or lack of thereof. Data mining capabilities are the cornerstones to perform such deep learning of system responses. For this reason static data mining capabilities were added last fiscal year (FY 15). In real applications, when dealing with complex multi-scale, multi-physics systems it seems natural that, during transients, the relevance of themore » different scales, and physics, would evolve over time. For these reasons the data mining capabilities have been extended allowing their application over time. In this writing it is reported a description of the new RAVEN capabilities implemented with several simple analytical tests to explain their application and highlight the proper implementation. The report concludes with the application of those newly implemented capabilities to the analysis of a simulation performed with the Bison code.« less
NASA Technical Reports Server (NTRS)
Noor, A. K.; Peters, J. M.
1981-01-01
Simple mixed models are developed for use in the geometrically nonlinear analysis of deep arches. A total Lagrangian description of the arch deformation is used, the analytical formulation being based on a form of the nonlinear deep arch theory with the effects of transverse shear deformation included. The fundamental unknowns comprise the six internal forces and generalized displacements of the arch, and the element characteristic arrays are obtained by using Hellinger-Reissner mixed variational principle. The polynomial interpolation functions employed in approximating the forces are one degree lower than those used in approximating the displacements, and the forces are discontinuous at the interelement boundaries. Attention is given to the equivalence between the mixed models developed herein and displacement models based on reduced integration of both the transverse shear and extensional energy terms. The advantages of mixed models over equivalent displacement models are summarized. Numerical results are presented to demonstrate the high accuracy and effectiveness of the mixed models developed and to permit a comparison of their performance with that of other mixed models reported in the literature.
Infrared emission and tidal interactions of spiral galaxies
NASA Technical Reports Server (NTRS)
Byrd, Gene G.
1987-01-01
Computer simulations of tidal interactions of spiral galaxies are used to attempt to understand recent discoveries about infrared (IR) emitting galaxies. It is found that the stronger tidal perturbation by a companion the more disk gas clouds are thrown into nucleus crossing orbits and the greater the velocity jumps crossing spiral arms. Both these tidally created characteristics would create more IR emission by high speed cloud collisions and more IR via effects of recently formed stars. This expectation at greater tidal perturbation matches the observation of greater IR emission for spiral galaxies with closer and/or more massive companions. The greater collision velocities found at stronger perturbations on the models will also result in higher dust temperature in the colliding clouds. In the IR pairs examined, most have only one member, the larger, detected and when both are detected, the larger is always the more luminous. In simulations and in a simple analytic description of the strong distance dependence of the tidal force, it is found that the big galaxy of a pair is more strongly affected than the small.
NASA Technical Reports Server (NTRS)
Kana, D. D.; Vargas, L. M.
1977-01-01
Transient excitation forces were applied separately to simple beam-and-mass launch vehicle and payload models to develop complex admittance functions for the interface and other appropriate points on the structures. These measured admittances were then analytically combined by a matrix representation to obtain a description of the coupled system dynamic characteristics. Response of the payload model to excitation of the launch vehicle model was predicted and compared with results measured on the combined models. These results are also compared with results of earlier work in which a similar procedure was employed except that steady-state sinusoidal excitation techniques were included. It is found that the method employing transient tests produces results that are better overall than the steady state methods. Furthermore, the transient method requires far less time to implement, and provides far better resolution in the data. However, the data acquisition and handling problem is more complex for this method. It is concluded that the transient test and admittance matrix prediction method can be a valuable tool for development of payload vibration tests.
Teichmüller TQFT vs. Chern-Simons theory
NASA Astrophysics Data System (ADS)
Mikhaylov, Victor
2018-04-01
Teichmüller TQFT is a unitary 3d topological theory whose Hilbert spaces are spanned by Liouville conformal blocks. It is related but not identical to PSL(2, ℝ) Chern-Simons theory. To physicists, it is known in particular in the context of 3d-3d correspondence and also in the holographic description of Virasoro conformal blocks. We propose that this theory can be defined by an analytically-continued Chern-Simons path-integral with an unusual integration cycle. On hyperbolic three-manifolds, this cycle is singled out by the requirement of invertible vielbein. Mathematically, our proposal translates a known conjecture by Andersen and Kashaev into a conjecture about the Kapustin-Witten equations. We further explain that Teichmüller TQFT is dual to complex SL(2, ℂ) Chern-Simons theory at integer level k = 1, clarifying some puzzles previously encountered in the 3d-3d correspondence literature. We also present a new simple derivation of complex Chern-Simons theories from the 6d (2,0) theory on a lens space with a transversely-holomorphic foliation.
A statistical method to estimate low-energy hadronic cross sections
NASA Astrophysics Data System (ADS)
Balassa, Gábor; Kovács, Péter; Wolf, György
2018-02-01
In this article we propose a model based on the Statistical Bootstrap approach to estimate the cross sections of different hadronic reactions up to a few GeV in c.m.s. energy. The method is based on the idea, when two particles collide a so-called fireball is formed, which after a short time period decays statistically into a specific final state. To calculate the probabilities we use a phase space description extended with quark combinatorial factors and the possibility of more than one fireball formation. In a few simple cases the probability of a specific final state can be calculated analytically, where we show that the model is able to reproduce the ratios of the considered cross sections. We also show that the model is able to describe proton-antiproton annihilation at rest. In the latter case we used a numerical method to calculate the more complicated final state probabilities. Additionally, we examined the formation of strange and charmed mesons as well, where we used existing data to fit the relevant model parameters.
Optimizations of Human Restraint Systems for Short-Period Acceleration
NASA Technical Reports Server (NTRS)
Payne, P. R.
1963-01-01
A restraint system's main function is to restrain its occupant when his vehicle is subjected to acceleration. If the restraint system is rigid and well-fitting (to eliminate slack) then it will transmit the vehicle acceleration to its occupant without modifying it in any way. Few present-day restraint systems are stiff enough to give this one-to-one transmission characteristic, and depending upon their dynamic characteristics and the nature of the vehicle's acceleration-time history, they will either magnify or attenuate the acceleration. Obviously an optimum restraint system will give maximum attenuation of an input acceleration. In the general case of an arbitrary acceleration input, a computer must be used to determine the optimum dynamic characteristics for the restraint system. Analytical solutions can be obtained for certain simple cases, however, and these cases are considered in this paper, after the concept of dynamic models of the human body is introduced. The paper concludes with a description of an analog computer specially developed for the Air Force to handle completely general mechanical restraint optimization programs of this type, where the acceleration input may be any arbitrary function of time.
An accurate behavioral model for single-photon avalanche diode statistical performance simulation
NASA Astrophysics Data System (ADS)
Xu, Yue; Zhao, Tingchen; Li, Ding
2018-01-01
An accurate behavioral model is presented to simulate important statistical performance of single-photon avalanche diodes (SPADs), such as dark count and after-pulsing noise. The derived simulation model takes into account all important generation mechanisms of the two kinds of noise. For the first time, thermal agitation, trap-assisted tunneling and band-to-band tunneling mechanisms are simultaneously incorporated in the simulation model to evaluate dark count behavior of SPADs fabricated in deep sub-micron CMOS technology. Meanwhile, a complete carrier trapping and de-trapping process is considered in afterpulsing model and a simple analytical expression is derived to estimate after-pulsing probability. In particular, the key model parameters of avalanche triggering probability and electric field dependence of excess bias voltage are extracted from Geiger-mode TCAD simulation and this behavioral simulation model doesn't include any empirical parameters. The developed SPAD model is implemented in Verilog-A behavioral hardware description language and successfully operated on commercial Cadence Spectre simulator, showing good universality and compatibility. The model simulation results are in a good accordance with the test data, validating high simulation accuracy.
Mathematical, Constitutive and Numerical Modelling of Catastrophic Landslides and Related Phenomena
NASA Astrophysics Data System (ADS)
Pastor, M.; Fernández Merodo, J. A.; Herreros, M. I.; Mira, P.; González, E.; Haddad, B.; Quecedo, M.; Tonni, L.; Drempetic, V.
2008-02-01
Mathematical and numerical models are a fundamental tool for predicting the behaviour of geostructures and their interaction with the environment. The term “mathematical model” refers to a mathematical description of the more relevant physical phenomena which take place in the problem being analyzed. It is indeed a wide area including models ranging from the very simple ones for which analytical solutions can be obtained to those more complicated requiring the use of numerical approximations such as the finite element method. During the last decades, mathematical, constitutive and numerical models have been very much improved and today their use is widespread both in industry and in research. One special case is that of fast catastrophic landslides, for which simplified methods are not able to provide accurate solutions in many occasions. Moreover, many finite element codes cannot be applied for propagation of the mobilized mass. The purpose of this work is to present an overview of the different alternative mathematical and numerical models which can be applied to both the initiation and propagation mechanisms of fast catastrophic landslides and other related problems such as waves caused by landslides.
Sindelka, Milan; Moiseyev, Nimrod
2006-04-27
We study a general problem of the translational/rotational/vibrational/electronic dynamics of a diatomic molecule exposed to an interaction with an arbitrary external electromagnetic field. The theory developed in this paper is relevant to a variety of specific applications, such as alignment or orientation of molecules by lasers, trapping of ultracold molecules in optical traps, molecular optics and interferometry, rovibrational spectroscopy of molecules in the presence of intense laser light, or generation of high order harmonics from molecules. Starting from the first quantum mechanical principles, we derive an appropriate molecular Hamiltonian suitable for description of the center of mass, rotational, vibrational, and electronic molecular motions driven by the field within the electric dipole approximation. Consequently, the concept of the Born-Oppenheimer separation between the electronic and the nuclear degrees of freedom in the presence of an electromagnetic field is introduced. Special cases of the dc/ac-field limits are then discussed separately. Finally, we consider a perturbative regime of a weak dc/ac field, and obtain simple analytic formulas for the associated Born-Oppenheimer translational/rotational/vibrational molecular Hamiltonian.
Novak, Ana; Gutiérrez-Zamora, Mercè; Domenech, Lluís; Suñé-Negre, Josep M; Miñarro, Montserrat; García-Montoya, Encarna; Llop, Josep M; Ticó, Josep R; Pérez-Lozano, Pilar
2018-02-01
A simple analytical method for simultaneous determination of phytosterols, cholesterol and squalene in lipid emulsions was developed owing to increased interest in their clinical effects. Method development was based on commonly used stationary (C 18 , C 8 and phenyl) and mobile phases (mixtures of acetonitrile, methanol and water) under isocratic conditions. Differences in stationary phases resulted in peak overlapping or coelution of different peaks. The best separation of all analyzed compounds was achieved on Zorbax Eclipse XDB C 8 (150 × 4.6 mm, 5 μm; Agilent) and ACN-H 2 O-MeOH, 80:19.5:0.5 (v/v/v). In order to achieve a shorter time of analysis, the method was further optimized and gradient separation was established. The optimized analytical method was validated and tested for routine use in lipid emulsion analyses. Copyright © 2017 John Wiley & Sons, Ltd.
ERIC Educational Resources Information Center
Al-Edwan, Zaid Suleiman
2016-01-01
The present study aimed at exploring the concepts of the security education in the textbooks of the national and civic education of the higher primary stage in Jordan. It adopted the descriptive analytical method. The study sample consisted of the textbooks of the national and civic education for the basic eighth, ninth and tenth grades. To…
Quo vadis, analytical chemistry?
Valcárcel, Miguel
2016-01-01
This paper presents an open, personal, fresh approach to the future of Analytical Chemistry in the context of the deep changes Science and Technology are anticipated to experience. Its main aim is to challenge young analytical chemists because the future of our scientific discipline is in their hands. A description of not completely accurate overall conceptions of our discipline, both past and present, to be avoided is followed by a flexible, integral definition of Analytical Chemistry and its cornerstones (viz., aims and objectives, quality trade-offs, the third basic analytical reference, the information hierarchy, social responsibility, independent research, transfer of knowledge and technology, interfaces to other scientific-technical disciplines, and well-oriented education). Obsolete paradigms, and more accurate general and specific that can be expected to provide the framework for our discipline in the coming years are described. Finally, the three possible responses of analytical chemists to the proposed changes in our discipline are discussed.
Simple waves in a two-component Bose-Einstein condensate
NASA Astrophysics Data System (ADS)
Ivanov, S. K.; Kamchatnov, A. M.
2018-04-01
We study the dynamics of so-called simple waves in a two-component Bose-Einstein condensate. The evolution of the condensate is described by Gross-Pitaevskii equations which can be reduced for these simple wave solutions to a system of ordinary differential equations which coincide with those derived by Ovsyannikov for the two-layer fluid dynamics. We solve the Ovsyannikov system for two typical situations of large and small difference between interspecies and intraspecies nonlinear interaction constants. Our analytic results are confirmed by numerical simulations.
Spin Seebeck effect in a simple ferromagnet near T c: a Ginzburg-Landau approach
NASA Astrophysics Data System (ADS)
Adachi, Hiroto; Yamamoto, Yutaka; Ichioka, Masanori
2018-04-01
A time-dependent Ginzburg-Landau theory is used to examine the longitudinal spin Seebeck effect in a simple ferromagnet in the vicinity of the Curie temperature T c. It is shown analytically that the spin Seebeck effect is proportional to the magnetization near T c, whose result is in line with the previous numerical finding. It is argued that the present result can be tested experimentally using a simple magnetic system such as EuO/Pt or EuS/Pt.
26 CFR 25.6019-4 - Description of property listed on return.
Code of Federal Regulations, 2010 CFR
2010-04-01
..., amount of principal unpaid, rate of interest and whether simple or compound, and date to which interest..., rate of interest, date or dates on which interest is payable, series number where there is more than... amount of such accrued income shall be separately set forth. Description of the seller's interest in land...
Waves and rays in plano-concave laser cavities: I. Geometric modes in the paraxial approximation
NASA Astrophysics Data System (ADS)
Barré, N.; Romanelli, M.; Lebental, M.; Brunel, M.
2017-05-01
Eigenmodes of laser cavities are studied theoretically and experimentally in two companion papers, with the aim of making connections between undulatory and geometric properties of light. In this first paper, we focus on macroscopic open-cavity lasers with localized gain. The model is based on the wave equation in the paraxial approximation; experiments are conducted with a simple diode-pumped Nd:YAG laser with a variable cavity length. After recalling fundamentals of laser beam optics, we consider plano-concave cavities with on-axis or off-axis pumping, with emphasis put on degenerate cavity lengths, where modes of different order resonate at the same frequency, and combine to form surprising transverse beam profiles. Degeneracy leads to the oscillation of so-called geometric modes whose properties can be understood, to a certain extent, also within a ray optics picture. We first provide a heuristic description of these modes, based on geometric reasoning, and then show more rigorously how to derive them analytically by building wave superpositions, within the framework of paraxial wave optics. The numerical methods, based on the Fox-Li approach, are described in detail. The experimental setup, including the imaging system, is also detailed and relatively simple to reproduce. The aim is to facilitate implementation of both the numerics and of the experiments, and to show that one can have access not only to the common higher-order modes but also to more exotic patterns.
Crowd Sourcing Data Collection through Amazon Mechanical Turk
2013-09-01
The first recognition study consisted of a Panel Study using a simple detection protocol, in which participants were presented with vignettes and, for...variability than the crowdsourcing data set, hewing more closely to the year 1 verbs of interest and simple description grammar . The DT:PS data were...Study RT: PS Recognition Task: Panel Study RT: RT Recognition Task: Round Table S3 Amazon Simple Storage Service SVPA Single Verb Present /Absent
Towards an analytical framework for tailoring supercontinuum generation.
Castelló-Lurbe, David; Vermeulen, Nathalie; Silvestre, Enrique
2016-11-14
A fully analytical toolbox for supercontinuum generation relying on scenarios without pulse splitting is presented. Furthermore, starting from the new insights provided by this formalism about the physical nature of direct and cascaded dispersive wave emission, a unified description of this radiation in both normal and anomalous dispersion regimes is derived. Previously unidentified physics of broadband spectra reported in earlier works is successfully explained on this basis. Finally, a foundry-compatible few-millimeters-long silicon waveguide allowing octave-spanning supercontinuum generation pumped at telecom wavelengths in the normal dispersion regime is designed, hence showcasing the potential of this new analytical approach.
Feng, Juanjuan; Sun, Min; Bu, Yanan; Luo, Chuannan
2016-03-01
Stir bar sorptive extraction is an environmentally friendly microextraction technique based on a stir bar with various sorbents. A commercial stirrer is a good support, but it has not been used in stir bar sorptive extraction due to difficult modification. A stirrer was modified with carbon nanoparticles by a simple carbon deposition process in flame and characterized by scanning electron microscopy and energy-dispersive X-ray spectrometry. A three-dimensional porous coating was formed with carbon nanoparticles. In combination with high-performance liquid chromatography, the stir bar was evaluated using five polycyclic aromatic hydrocarbons as model analytes. Conditions including extraction time and temperature, ionic strength, and desorption solvent were investigated by a factor-by-factor optimization method. The established method exhibited good linearity (0.01-10 μg/L) and low limits of quantification (0.01 μg/L). It was applied to detect model analytes in environmental water samples. No analyte was detected in river water, and five analytes were quantified in rain water. The recoveries of five analytes in two samples with spiked at 2 μg/L were in the range of 92.2-106% and 93.4-108%, respectively. The results indicated that the carbon nanoparticle-coated stirrer was an efficient stir bar for extraction analysis of some polycyclic aromatic hydrocarbons. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Empirical testing of an analytical model predicting electrical isolation of photovoltaic models
NASA Astrophysics Data System (ADS)
Garcia, A., III; Minning, C. P.; Cuddihy, E. F.
A major design requirement for photovoltaic modules is that the encapsulation system be capable of withstanding large DC potentials without electrical breakdown. Presented is a simple analytical model which can be used to estimate material thickness to meet this requirement for a candidate encapsulation system or to predict the breakdown voltage of an existing module design. A series of electrical tests to verify the model are described in detail. The results of these verification tests confirmed the utility of the analytical model for preliminary design of photovoltaic modules.
Sánchez, C; Ortega, B; Wei, J L; Tang, J; Capmany, J
2013-03-25
We provide an analytical study on the propagation effects of a directly modulated OOFDM signal through a dispersive fiber and subsequent photo-detection. The analysis includes the effects of the laser operation point and the interplay between chromatic dispersion and laser chirp. The final expression allows to understand the physics behind the transmission of a multi-carrier signal in the presence of residual frequency modulation and the description of the induced intermodulation distortion gives us a detailed insight into the diferent intermodulation products which impair the recovered signal at the receiver-end side. Numerical comparisons between transmission simulations results and those provided by evaluating the expression obtained are carried out for different laser operation points. Results obtained by changing the fiber length, laser parameters and using single mode fiber with negative and positive dispersion are calculated in order to demonstrate the validity and versatility of the theory provided in this paper. Therefore, a novel analytical formulation is presented as a versatile tool for the description and study of IM/DD OOFDM systems with variable design parameters.
Analytical transition-matrix treatment of electric multipole polarizabilities of hydrogen-like atoms
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kharchenko, V.F., E-mail: vkharchenko@bitp.kiev.ua
2015-04-15
The direct transition-matrix approach to the description of the electric polarization of the quantum bound system of particles is used to determine the electric multipole polarizabilities of the hydrogen-like atoms. It is shown that in the case of the bound system formed by the Coulomb interaction the corresponding inhomogeneous integral equation determining an off-shell scattering function, which consistently describes virtual multiple scattering, can be solved exactly analytically for all electric multipole polarizabilities. Our method allows to reproduce the known Dalgarno–Lewis formula for electric multipole polarizabilities of the hydrogen atom in the ground state and can also be applied to determinemore » the polarizability of the atom in excited bound states. - Highlights: • A new description for electric polarization of hydrogen-like atoms. • Expression for multipole polarizabilities in terms of off-shell scattering functions. • Derivation of integral equation determining the off-shell scattering function. • Rigorous analytic solving the integral equations both for ground and excited states. • Study of contributions of virtual multiple scattering to electric polarizabilities.« less
Oscillations and Multiple Equilibria in Microvascular Blood Flow.
Karst, Nathaniel J; Storey, Brian D; Geddes, John B
2015-07-01
We investigate the existence of oscillatory dynamics and multiple steady-state flow rates in a network with a simple topology and in vivo microvascular blood flow constitutive laws. Unlike many previous analytic studies, we employ the most biologically relevant models of the physical properties of whole blood. Through a combination of analytic and numeric techniques, we predict in a series of two-parameter bifurcation diagrams a range of dynamical behaviors, including multiple equilibria flow configurations, simple oscillations in volumetric flow rate, and multiple coexistent limit cycles at physically realizable parameters. We show that complexity in network topology is not necessary for complex behaviors to arise and that nonlinear rheology, in particular the plasma skimming effect, is sufficient to support oscillatory dynamics similar to those observed in vivo.
NASA Astrophysics Data System (ADS)
Zou, Junyan; Song, Weijia; Xie, Weiguang; Huang, Bo; Yang, Huidong; Luo, Zhi
2018-03-01
Here, we report a simple strategy to prepare highly sensitive surface-enhanced Raman spectroscopy (SERS) substrates based on Ag decorated Cu2O nanoparticles by combining two common techniques, viz, thermal oxidation growth of Cu2O nanoparticles and magnetron sputtering fabrication of a Ag nanoparticle film. Methylene blue is used as the Raman analyte for the SERS study, and the substrates fabricated under optimized conditions have very good sensitivity (analytical enhancement factor ˜108), stability, and reproducibility. A linear dependence of the SERS intensities with the concentration was obtained with an R 2 value >0.9. These excellent properties indicate that the substrate has great potential in the detection of biological and chemical substances.
Estimation of surface temperature in remote pollution measurement experiments
NASA Technical Reports Server (NTRS)
Gupta, S. K.; Tiwari, S. N.
1978-01-01
A simple algorithm has been developed for estimating the actual surface temperature by applying corrections to the effective brightness temperature measured by radiometers mounted on remote sensing platforms. Corrections to effective brightness temperature are computed using an accurate radiative transfer model for the 'basic atmosphere' and several modifications of this caused by deviations of the various atmospheric and surface parameters from their base model values. Model calculations are employed to establish simple analytical relations between the deviations of these parameters and the additional temperature corrections required to compensate for them. Effects of simultaneous variation of two parameters are also examined. Use of these analytical relations instead of detailed radiative transfer calculations for routine data analysis results in a severalfold reduction in computation costs.
Gupta, Vinita; Davancaze, Teresa; Good, Jeremy; Kalia, Navdeep; Anderson, Michael; Wallin, Jeffrey J; Brady, Ann; Song, An; Xu, Wenfeng
2016-12-01
Immune-checkpoint inhibitors are presumed to break down the tolerogenic state of immune cells by activating T-lymphocytes that release cytokines and enhance effector cell function for elimination of tumors. Measurement of cytokines is being pursued for better understanding of the mechanism of action of immune-checkpoint inhibitors, as well as to identify potential predictive biomarkers. In this study, we show bioanalytical qualification of cytokine assays in plasma on a novel multi-analyte immunoassay platform, Simple Plex ™ . The qualified assays exhibited excellent sensitivity as evidenced by measurement of all samples within the quantifiable range. The accuracy and precision were 80-120% and 10%, respectively. The qualified assays will be useful in assessing mechanism of action cancer immunotherapies.
Description of deformed nuclei in the sdg boson model
NASA Astrophysics Data System (ADS)
Li, S. C.; Kuyucak, S.
1996-02-01
We present a study of deformed nuclei in the framework of the sdg interacting boson model utilizing both numerical diagonalization and analytical {1}/{N} expansion techniques. The focus is on the description of high-spin states which have recently become computationally accessible through the use of computer algebra in the {1}/{N} expansion formalism. A systematic study is made of high-spin states in rare-earth and actinide nuclei.
Self-descriptions on LinkedIn: Recruitment or friendship identity?
Garcia, Danilo; Cloninger, Kevin M; Granjard, Alexandre; Molander-Söderholm, Kristian; Amato, Clara; Sikström, Sverker
2018-04-26
We used quantitative semantics to find clusters of words in LinkedIn users' self-descriptions to an employer or a friend. Some of these clusters discriminated between worker and friend conditions (e.g., flexible vs. caring) and between LinkedIn users with high and low education (e.g., analytical vs. messy). © 2018 The Institute of Psychology, Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.
Analytical model for minority games with evolutionary learning
NASA Astrophysics Data System (ADS)
Campos, Daniel; Méndez, Vicenç; Llebot, Josep E.; Hernández, Germán A.
2010-06-01
In a recent work [D. Campos, J.E. Llebot, V. Méndez, Theor. Popul. Biol. 74 (2009) 16] we have introduced a biological version of the Evolutionary Minority Game that tries to reproduce the intraspecific competition for limited resources in an ecosystem. In comparison with the complex decision-making mechanisms used in standard Minority Games, only two extremely simple strategies ( juveniles and adults) are accessible to the agents. Complexity is introduced instead through an evolutionary learning rule that allows younger agents to learn taking better decisions. We find that this game shows many of the typical properties found for Evolutionary Minority Games, like self-segregation behavior or the existence of an oscillation phase for a certain range of the parameter values. However, an analytical treatment becomes much easier in our case, taking advantage of the simple strategies considered. Using a model consisting of a simple dynamical system, the phase diagram of the game (which differentiates three phases: adults crowd, juveniles crowd and oscillations) is reproduced.
NASA Technical Reports Server (NTRS)
Ng, C. F.
1988-01-01
Static postbuckling and nonlinear dynamic analysis of plates are usually accomplished by multimode analyses, although the methods are complicated and do not give straightforward understanding of the nonlinear behavior. Assuming single-mode transverse displacement, a simple formula is derived for the transverse load displacement relationship of a plate under in-plane compression. The formula is used to derive a simple analytical expression for the static postbuckling displacement and nonlinear dynamic responses of postbuckled plates under sinusoidal or random excitation. Regions with softening and hardening spring behavior are identified. Also, the highly nonlinear motion of snap-through and its effects on the overall dynamic response can be easily interpreted using the single-mode formula. Theoretical results are compared with experimental results obtained using a buckled aluminum panel, using discrete frequency and broadband point excitation. Some important effects of the snap-through motion on the dynamic response of the postbuckled plates are found.
A simple stochastic weather generator for ecological modeling
A.G. Birt; M.R. Valdez-Vivas; R.M. Feldman; C.W. Lafon; D. Cairns; R.N. Coulson; M. Tchakerian; W. Xi; Jim Guldin
2010-01-01
Stochastic weather generators are useful tools for exploring the relationship between organisms and their environment. This paper describes a simple weather generator that can be used in ecological modeling projects. We provide a detailed description of methodology, and links to full C++ source code (http://weathergen.sourceforge.net) required to implement or modify...
A Simple Treatment of the Liquidity Trap for Intermediate Macroeconomics Courses
ERIC Educational Resources Information Center
Buttet, Sebastien; Roy, Udayan
2014-01-01
Several leading undergraduate intermediate macroeconomics textbooks now include a simple reduced-form New Keynesian model of short-run dynamics (alongside the IS-LM model). Unfortunately, there is no accompanying description of how the zero lower bound on nominal interest rates affects the model. In this article, the authors show how the…
ERIC Educational Resources Information Center
Datchuk, Shawn M.; Kubina, Richard M., Jr.
2017-01-01
The present study used a multiple-baseline, single-case experimental design to investigate the effects of a multicomponent intervention on construction of simple sentences and word sequences. The intervention entailed sequential delivery of sentence instruction and frequency building to a performance criterion and paragraph instruction.…
Quantitation & Case-Study-Driven Inquiry to Enhance Yeast Fermentation Studies
ERIC Educational Resources Information Center
Grammer, Robert T.
2012-01-01
We propose a procedure for the assay of fermentation in yeast in microcentrifuge tubes that is simple and rapid, permitting assay replicates, descriptive statistics, and the preparation of line graphs that indicate reproducibility. Using regression and simple derivatives to determine initial velocities, we suggest methods to compare the effects of…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Margevicius, Kristen J.; Generous, Nicholas; Abeyta, Esteban
Epidemiological modeling for infectious disease is important for disease management and its routine implementation needs to be facilitated through better description of models in an operational context. A standardized model characterization process that allows selection or making manual comparisons of available models and their results is currently lacking. A key need is a universal framework to facilitate model description and understanding of its features. Los Alamos National Laboratory (LANL) has developed a comprehensive framework that can be used to characterize an infectious disease model in an operational context. The framework was developed through a consensus among a panel of subjectmore » matter experts. In this paper, we describe the framework, its application to model characterization, and the development of the Biosurveillance Analytics Resource Directory (BARD; http://brd.bsvgateway.org/brd/), to facilitate the rapid selection of operational models for specific infectious/communicable diseases. We offer this framework and associated database to stakeholders of the infectious disease modeling field as a tool for standardizing model description and facilitating the use of epidemiological models.« less
Ram Pressure Stripping Made Easy: An Analytical Approach
NASA Astrophysics Data System (ADS)
Köppen, J.; Jáchym, P.; Taylor, R.; Palouš, J.
2018-06-01
The removal of gas by ram pressure stripping of galaxies is treated by a purely kinematic description. The solution has two asymptotic limits: if the duration of the ram pressure pulse exceeds the period of vertical oscillations perpendicular to the galactic plane, the commonly used quasi-static criterion of Gunn & Gott is obtained which uses the maximum ram pressure that the galaxy has experienced along its orbit. For shorter pulses the outcome depends on the time-integrated ram pressure. This parameter pair fully describes the gas mass fraction that is stripped from a given galaxy. This approach closely reproduces results from SPH simulations. We show that typical galaxies follow a very tight relation in this parameter space corresponding to a pressure pulse length of about 300 Myr. Thus, the Gunn & Gott criterion provides a good description for galaxies in larger clusters. Applying the analytic description to a sample of 232 Virgo galaxies from the GoldMine database, we show that the ICM provides indeed the ram pressures needed to explain the deficiencies. We also can distinguish current and past strippers, including objects whose stripping state was unknown.
Margevicius, Kristen J; Generous, Nicholas; Abeyta, Esteban; Althouse, Ben; Burkom, Howard; Castro, Lauren; Daughton, Ashlynn; Del Valle, Sara Y.; Fairchild, Geoffrey; Hyman, James M.; Kiang, Richard; Morse, Andrew P.; Pancerella, Carmen M.; Pullum, Laura; Ramanathan, Arvind; Schlegelmilch, Jeffrey; Scott, Aaron; Taylor-McCabe, Kirsten J; Vespignani, Alessandro; Deshpande, Alina
2016-01-01
Epidemiological modeling for infectious disease is important for disease management and its routine implementation needs to be facilitated through better description of models in an operational context. A standardized model characterization process that allows selection or making manual comparisons of available models and their results is currently lacking. A key need is a universal framework to facilitate model description and understanding of its features. Los Alamos National Laboratory (LANL) has developed a comprehensive framework that can be used to characterize an infectious disease model in an operational context. The framework was developed through a consensus among a panel of subject matter experts. In this paper, we describe the framework, its application to model characterization, and the development of the Biosurveillance Analytics Resource Directory (BARD; http://brd.bsvgateway.org/brd/), to facilitate the rapid selection of operational models for specific infectious/communicable diseases. We offer this framework and associated database to stakeholders of the infectious disease modeling field as a tool for standardizing model description and facilitating the use of epidemiological models. PMID:26820405
Margevicius, Kristen J; Generous, Nicholas; Abeyta, Esteban; Althouse, Ben; Burkom, Howard; Castro, Lauren; Daughton, Ashlynn; Del Valle, Sara Y; Fairchild, Geoffrey; Hyman, James M; Kiang, Richard; Morse, Andrew P; Pancerella, Carmen M; Pullum, Laura; Ramanathan, Arvind; Schlegelmilch, Jeffrey; Scott, Aaron; Taylor-McCabe, Kirsten J; Vespignani, Alessandro; Deshpande, Alina
2016-01-01
Epidemiological modeling for infectious disease is important for disease management and its routine implementation needs to be facilitated through better description of models in an operational context. A standardized model characterization process that allows selection or making manual comparisons of available models and their results is currently lacking. A key need is a universal framework to facilitate model description and understanding of its features. Los Alamos National Laboratory (LANL) has developed a comprehensive framework that can be used to characterize an infectious disease model in an operational context. The framework was developed through a consensus among a panel of subject matter experts. In this paper, we describe the framework, its application to model characterization, and the development of the Biosurveillance Analytics Resource Directory (BARD; http://brd.bsvgateway.org/brd/), to facilitate the rapid selection of operational models for specific infectious/communicable diseases. We offer this framework and associated database to stakeholders of the infectious disease modeling field as a tool for standardizing model description and facilitating the use of epidemiological models.
Margevicius, Kristen J.; Generous, Nicholas; Abeyta, Esteban; ...
2016-01-28
Epidemiological modeling for infectious disease is important for disease management and its routine implementation needs to be facilitated through better description of models in an operational context. A standardized model characterization process that allows selection or making manual comparisons of available models and their results is currently lacking. A key need is a universal framework to facilitate model description and understanding of its features. Los Alamos National Laboratory (LANL) has developed a comprehensive framework that can be used to characterize an infectious disease model in an operational context. The framework was developed through a consensus among a panel of subjectmore » matter experts. In this paper, we describe the framework, its application to model characterization, and the development of the Biosurveillance Analytics Resource Directory (BARD; http://brd.bsvgateway.org/brd/), to facilitate the rapid selection of operational models for specific infectious/communicable diseases. We offer this framework and associated database to stakeholders of the infectious disease modeling field as a tool for standardizing model description and facilitating the use of epidemiological models.« less
ERIC Educational Resources Information Center
Gron, Liz U.; Bradley, Shelly B.; McKenzie, Jennifer R.; Shinn, Sara E.; Teague, M. Warfield
2013-01-01
This paper presents the use of simple, outcome-based assessment tools to design and evaluate the first semester of a new introductory laboratory program created to teach green analytical chemistry using environmental samples. This general chemistry laboratory program, like many introductory courses, has a wide array of stakeholders within and…
ERIC Educational Resources Information Center
Lindquist, David H.
2012-01-01
Examining history from the perspective of investigators who wrestle with involved scenarios for which no simple answers exist, or from which no obvious conclusions can be drawn, allows students to understand the historiographic process and the complex nature of historical events, while gaining valuable practice in applying analytical and critical…
Durán, Gema M; Contento, Ana M; Ríos, Ángel
2013-11-01
Based on the highly sensitive fluorescence change of water-soluble CdSe/ZnS core-shell quantum dots (QD) by paraquat herbicide, a simple, rapid and reproducible methodology was developed to selectively determine paraquat (PQ) in water samples. The methodology enabled the use of simple pretreatment procedure based on the simple water solubilization of CdSe/ZnS QDs with hydrophilic heterobifunctional thiol ligands, such as 3-mercaptopropionic acid (3-MPA), using microwave irradiation. The resulting water-soluble QDs exhibit a strong fluorescence emission at 596 nm with a high and reproducible photostability. The proposed analytical method thus satisfies the need for a simple, sensible and rapid methodology to determine residues of paraquat in water samples, as required by the increasingly strict regulations for health protection introduced in recent years. The sensitivity of the method, expressed as detection limits, was as low as 3.0 ng L(-1). The lineal range was between 10-5×10(3) ng L(-1). RSD values in the range of 71-102% were obtained. The analytical applicability of proposed method was demonstrated by analyzing water samples from different procedence. Copyright © 2013 Elsevier B.V. All rights reserved.
1989-06-23
Iterations .......................... 86 3.2 Comparison between MACH and POLAR ......................... 90 3.3 Flow Chart for VSTS Algorithm...The most recent changes are: a) development of the VSTS (velocity space topology search) algorithm for calculating particle densities b) extension...with simple analytic models. The largest modification of the MACH code was the implementation of the VSTS procedure, which constituted a complete
Experimental and analytical studies for the NASA carbon fiber risk assessment
NASA Technical Reports Server (NTRS)
1980-01-01
Various experimental and analytical studies performed for the NASA carbon fiber risk assessment program are described with emphasis on carbon fiber characteristics, sensitivity of electrical equipment and components to shorting or arcing by carbon fibers, attenuation effect of carbon fibers on aircraft landing aids, impact of carbon fibers on industrial facilities. A simple method of estimating damage from airborne carbon fibers is presented.
R. Haggerty
2013-01-01
In this technical note, a steady-state analytical solution of concentrations of a parent solute reacting to a daughter solute, both of which are undergoing transport and multirate mass transfer, is presented. Although the governing equations are complicated, the resulting solution can be expressed in simple terms. A function of the ratio of concentrations, In (daughter...
Analytical study of shimmy of airplane wheels
NASA Technical Reports Server (NTRS)
Bourcier De Carbon, Christian
1952-01-01
The problem of shimmy of a castering wheel, such as the nose wheel of a tricycle gear airplane, is treated analytically. The flexibility of the tire is considered to be the primary cause of shimmy. The rather simple theory developed agrees rather well with previous experimental results. The author suggests that shimmy may be eliminated through a suitable choice of landing gear dimensions in lieu of a damper.
NASA Astrophysics Data System (ADS)
Fedyushin, B. T.
1992-01-01
The concepts developed earlier are used to propose a simple analytic model describing the spatial-temporal distribution of a mechanical load (pressure, impulse) resulting from interaction of laser radiation with a planar barrier surrounded by air. The correctness of the model is supported by a comparison with experimental results.
NASA Astrophysics Data System (ADS)
Nakada, Tomohiro; Takadama, Keiki; Watanabe, Shigeyoshi
This paper proposes the classification method using Bayesian analytical method to classify the time series data in the international emissions trading market depend on the agent-based simulation and compares the case with Discrete Fourier transform analytical method. The purpose demonstrates the analytical methods mapping time series data such as market price. These analytical methods have revealed the following results: (1) the classification methods indicate the distance of mapping from the time series data, it is easier the understanding and inference than time series data; (2) these methods can analyze the uncertain time series data using the distance via agent-based simulation including stationary process and non-stationary process; and (3) Bayesian analytical method can show the 1% difference description of the emission reduction targets of agent.
An Introduction to Path Analysis
ERIC Educational Resources Information Center
Wolfe, Lee M.
1977-01-01
The analytical procedure of path analysis is described in terms of its use in nonexperimental settings in the social sciences. The description assumes a moderate statistical background on the part of the reader. (JKS)
NASA Astrophysics Data System (ADS)
Vicsek, Tamas
1997-03-01
It is demonstrated that a wide range of experimental results on biological motion can be successfully interpreted in terms of statistical physics motivated models taking into account the relevant microscopic details of motor proteins and allowing analytic solutions. Two important examples are considered, i) the motion of a single kinesin molecule along microtubules inside individual cells and ii) muscle contraction which is a macroscopic phenomenon due to the collective action of a large number of myosin heads along actin filaments. i) Recently individual two-headed kinesin molecules have been studied in in vitro motility assays revealing a number of their peculiar transport properties. Here we propose a simple and robust model for the kinesin stepping process with elastically coupled Brownian heads showing all of these properties. The analytic treatment of our model results in a very good fit to the experimental data and practically has no free parameters. ii) Myosin is an ATPase enzyme that converts the chemical energy stored in ATP molecules into mechanical work. During muscle contraction, the myosin cross-bridges attach to the actin filaments and exert force on them yielding a relative sliding of the actin and myosin filaments. In this paper we present a simple mechanochemical model for the cross-bridge interaction involving the relevant kinetic data and providing simple analytic solutions for the mechanical properties of muscle contraction, such as the force-velocity relationship or the relative number of the attached cross-bridges. So far the only analytic formula which could be fitted to the measured force-velocity curves has been the well known Hill equation containing parameters lacking clear microscopic origin. The main advantages of our new approach are that it explicitly connects the mechanical data with the kinetic data and the concentration of the ATP and ATPase products and as such it leads to new analytic solutions which agree extremely well with a wide range of experimental curves, while the parameters of the corresponding expressions have well defined microscopic meaning.
Simple analytical relations for ship bow waves
NASA Astrophysics Data System (ADS)
Noblesse, Francis; Delhommeau, G.?Rard; Guilbaud, Michel; Hendrix, Dane; Yang, Chi
Simple analytical relations for the bow wave generated by a ship in steady motion are given. Specifically, simple expressions that define the height of a ship bow wave, the distance between the ship stem and the crest of the bow wave, the rise of water at the stem, and the bow wave profile, explicitly and without calculations, in terms of the ship speed, draught, and waterline entrance angle, are given. Another result is a simple criterion that predicts, also directly and without calculations, when a ship in steady motion cannot generate a steady bow wave. This unsteady-flow criterion predicts that a ship with a sufficiently fine waterline, specifically with waterline entrance angle 2, may generate a steady bow wave at any speed. However, a ship with a fuller waterline (25E) can only generate a steady bow wave if the ship speed is higher than a critical speed, defined in terms of αE by a simple relation. No alternative criterion for predicting when a ship in steady motion does not generate a steady bow wave appears to exist. A simple expression for the height of an unsteady ship bow wave is also given. In spite of their remarkable simplicity, the relations for ship bow waves obtained in the study (using only rudimentary physical and mathematical considerations) are consistent with experimental measurements for a number of hull forms having non-bulbous wedge-shaped bows with small flare angle, and with the authors' measurements and observations for a rectangular flat plate towed at a yaw angle.
Force 2025 and Beyond Strategic Force Design Analytic Model
2017-01-12
depiction of the core ideas of our force design model. Figure 1: Description of Force Design Model Figure 2 shows an overview of our methodology ...the F2025B Force Design Analytic Model research conducted by TRAC- MTRY and the Naval Postgraduate School. Our research develops a methodology for...designs. We describe a data development methodology that characterizes the data required to construct a force design model using our approach. We
Summary of investigations of engine response to distorted inlet conditions
NASA Technical Reports Server (NTRS)
Biesiadny, T. J.; Braithwaite, W. M.; Soeder, R. H.; Abdelwahab, M.
1986-01-01
A survey is presented of experimental and analytical experience of the NASA Lewis Research Center in engine response to inlet temperature and pressure distortions. This includes a description of the hardware and techniques employed, and a summary of the highlights of experimental investigations and analytical modeling. Distortion devices successfully simulated inlet distortion, and knowledge was gained about compression system response to different types of distortion. A list of NASA research references is included.
Processing plutonium-contaminated soil on Johnston Atoll
DOE Office of Scientific and Technical Information (OSTI.GOV)
Moroney, K.; Moroney, J. III; Turney, J.
1994-07-01
This article describes a cleanup project to process plutonium- and americium-contaminated soil on Johnston Atoll for volume reduction. Thermo Analytical`s (TMA`s) segmented gate system (SGS) for this remedial operation has been in successful on-site operation since 1992. Topics covered include the basis for development, a description of the Johnston Atoll; the significance of results; the benefits of the technology; applicability to other radiologically contaminated sites. 7 figs., 1 tab.
NASA Astrophysics Data System (ADS)
Marrocco, Michele
2007-11-01
Fluorescence correlation spectroscopy is fundamental in many physical, chemical and biological studies of molecular diffusion. However, the concept of fluorescence correlation is founded on the assumption that the analytical description of the correlation decay of diffusion can be achieved if the spatial profile of the detected volume obeys a three-dimensional Gaussian distribution. In the present Letter, the analytical result is instead proven for the fundamental Gaussian-Lorentzian profile.
Vandenabeele-Trambouze, O; Claeys-Bruno, M; Dobrijevic, M; Rodier, C; Borruat, G; Commeyras, A; Garrelly, L
2005-02-01
The need for criteria to compare different analytical methods for measuring extraterrestrial organic matter at ultra-trace levels in relatively small and unique samples (e.g., fragments of meteorites, micrometeorites, planetary samples) is discussed. We emphasize the need to standardize the description of future analyses, and take the first step toward a proposed international laboratory network for performance testing.
The Attentional Drift Diffusion Model of Simple Perceptual Decision-Making.
Tavares, Gabriela; Perona, Pietro; Rangel, Antonio
2017-01-01
Perceptual decisions requiring the comparison of spatially distributed stimuli that are fixated sequentially might be influenced by fluctuations in visual attention. We used two psychophysical tasks with human subjects to investigate the extent to which visual attention influences simple perceptual choices, and to test the extent to which the attentional Drift Diffusion Model (aDDM) provides a good computational description of how attention affects the underlying decision processes. We find evidence for sizable attentional choice biases and that the aDDM provides a reasonable quantitative description of the relationship between fluctuations in visual attention, choices and reaction times. We also find that exogenous manipulations of attention induce choice biases consistent with the predictions of the model.
Truth and probability in evolutionary games
NASA Astrophysics Data System (ADS)
Barrett, Jeffrey A.
2017-01-01
This paper concerns two composite Lewis-Skyrms signalling games. Each consists in a base game that evolves a language descriptive of nature and a metagame that coevolves a language descriptive of the base game and its evolving language. The first composite game shows how a pragmatic notion of truth might coevolve with a simple descriptive language. The second shows how a pragmatic notion of probability might similarly coevolve. Each of these pragmatic notions is characterised by the particular game and role that it comes to play in the game.
77 FR 61791 - System of Records; Presidential Management Fellows Program
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-11
... program personnel for the following reasons: a. To determine basic program eligibility and to evaluate... descriptive statistics and analytical studies in support of the function for which the records are collected...
Moving from Descriptive to Causal Analytics: Case Study of the Health Indicators Warehouse
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schryver, Jack C.; Shankar, Mallikarjun; Xu, Songhua
The KDD community has described a multitude of methods for knowledge discovery on large datasets. We consider some of these methods and integrate them into an analyst s workflow that proceeds from the data-centric descriptive level to the model-centric causal level. Examples of the workflow are shown for the Health Indicators Warehouse, which is a public database for community health information that is a potent resource for conducting data science on a medium scale. We demonstrate the potential of HIW as a source of serious visual analytics efforts by showing correlation matrix visualizations, multivariate outlier analysis, multiple linear regression ofmore » Medicare costs, and scatterplot matrices for a broad set of health indicators. We conclude by sketching the first steps toward a causal dependence hypothesis.« less
Bubble motion in a rotating liquid body. [ground based tests for space shuttle experiments
NASA Technical Reports Server (NTRS)
Annamalai, P.; Subramanian, R. S.; Cole, R.
1982-01-01
The behavior of a single gas bubble inside a rotating liquid-filled sphere has been investigated analytically and experimentally as part of ground-based investigations aimed at aiding in the design and interpretation of Shuttle experiments. In the analysis, a quasi-static description of the motion of a bubble was developed in the limit of small values of the Taylor number. A series of rotation experiments using air bubbles and silicone oils were designed to match the conditions specified in the analysis, i.e., the bubble size, sphere rotation rate, and liquid kinematic viscosity were chosen such that the Taylor number was much less than unity. The analytical description predicts the bubble velocity and its asymptotic location. It is shown that the asymptotic position is removed from the axis of rotation.
Firing rate dynamics in recurrent spiking neural networks with intrinsic and network heterogeneity.
Ly, Cheng
2015-12-01
Heterogeneity of neural attributes has recently gained a lot of attention and is increasing recognized as a crucial feature in neural processing. Despite its importance, this physiological feature has traditionally been neglected in theoretical studies of cortical neural networks. Thus, there is still a lot unknown about the consequences of cellular and circuit heterogeneity in spiking neural networks. In particular, combining network or synaptic heterogeneity and intrinsic heterogeneity has yet to be considered systematically despite the fact that both are known to exist and likely have significant roles in neural network dynamics. In a canonical recurrent spiking neural network model, we study how these two forms of heterogeneity lead to different distributions of excitatory firing rates. To analytically characterize how these types of heterogeneities affect the network, we employ a dimension reduction method that relies on a combination of Monte Carlo simulations and probability density function equations. We find that the relationship between intrinsic and network heterogeneity has a strong effect on the overall level of heterogeneity of the firing rates. Specifically, this relationship can lead to amplification or attenuation of firing rate heterogeneity, and these effects depend on whether the recurrent network is firing asynchronously or rhythmically firing. These observations are captured with the aforementioned reduction method, and furthermore simpler analytic descriptions based on this dimension reduction method are developed. The final analytic descriptions provide compact and descriptive formulas for how the relationship between intrinsic and network heterogeneity determines the firing rate heterogeneity dynamics in various settings.
Structural analysis and design of multivariable control systems: An algebraic approach
NASA Technical Reports Server (NTRS)
Tsay, Yih Tsong; Shieh, Leang-San; Barnett, Stephen
1988-01-01
The application of algebraic system theory to the design of controllers for multivariable (MV) systems is explored analytically using an approach based on state-space representations and matrix-fraction descriptions. Chapters are devoted to characteristic lambda matrices and canonical descriptions of MIMO systems; spectral analysis, divisors, and spectral factors of nonsingular lambda matrices; feedback control of MV systems; and structural decomposition theories and their application to MV control systems.
Light-emitting diodes for analytical chemistry.
Macka, Mirek; Piasecki, Tomasz; Dasgupta, Purnendu K
2014-01-01
Light-emitting diodes (LEDs) are playing increasingly important roles in analytical chemistry, from the final analysis stage to photoreactors for analyte conversion to actual fabrication of and incorporation in microdevices for analytical use. The extremely fast turn-on/off rates of LEDs have made possible simple approaches to fluorescence lifetime measurement. Although they are increasingly being used as detectors, their wavelength selectivity as detectors has rarely been exploited. From their first proposed use for absorbance measurement in 1970, LEDs have been used in analytical chemistry in too many ways to make a comprehensive review possible. Hence, we critically review here the more recent literature on their use in optical detection and measurement systems. Cloudy as our crystal ball may be, we express our views on the future applications of LEDs in analytical chemistry: The horizon will certainly become wider as LEDs in the deep UV with sufficient intensity become available.
Class and Home Problems: Humidification, a True "Home" Problem for p. Chemical Engineer
ERIC Educational Resources Information Center
Condoret, Jean-Stephane
2012-01-01
The problem of maintaining hygrothermal comfort in a house is addressed using the chemical engineer's toolbox. A simple dynamic modelling proved to give a good description of the humidification of the house in winter, using a domestic humidifier. Parameters of the model were identified from a simple experiment. Surprising results, especially…
ERIC Educational Resources Information Center
Sobrero, Patricio; Valverde, Claudio
2013-01-01
A simple and cheap laboratory class is proposed to illustrate the lethal effect of UV radiation on bacteria and the operation of different DNA repair mechanisms. The class is divided into two sessions, an initial 3-hour experimental session and a second 2-hour analytical session. The experimental session involves two separate experiments: one…
Analytical expressions for stability regions in the Ince-Strutt diagram of Mathieu equation
NASA Astrophysics Data System (ADS)
Butikov, Eugene I.
2018-04-01
Simple analytical expressions are suggested for transition curves that separate, in the Ince-Strutt diagram, different types of solutions to the famous Mathieu equation. The derivations of these expressions in this paper rely on physically meaningful periodic solutions describing various regular motions of a familiar nonlinear mechanical system—a rigid planar pendulum with a vertically oscillating pivot. The paper is accompanied by a relevant simulation program.
Analytical solutions of Landau (1+1)-dimensional hydrodynamics
Wong, Cheuk-Yin; Sen, Abhisek; Gerhard, Jochen; ...
2014-12-17
To help guide our intuition, summarize important features, and point out essential elements, we review the analytical solutions of Landau (1+1)-dimensional hydrodynamics and exhibit the full evolution of the dynamics from the very beginning to subsequent times. Special emphasis is placed on the matching and the interplay between the Khalatnikov solution and the Riemann simple wave solution at the earliest times and in the edge regions at later times.
ERIC Educational Resources Information Center
Cepriá, Gemma; Salvatella, Luis
2014-01-01
All pH calculations for simple acid-base systems used in introductory courses on general or analytical chemistry can be carried out by using a general procedure requiring the use of predominance diagrams. In particular, the pH is calculated as the sum of an independent term equaling the average pK[subscript a] values of the acids involved in the…
Dawan, Phanphruk; Satarpai, Thiphol; Tuchinda, Patoomratana; Shiowatana, Juwadee; Siripinyanond, Atitaya
2017-01-01
A new analytical platform based on the use of thin-layer chromatography (TLC) coupled with paper-based analytical device (PAD) was developed for the determination of total capsaicinoids in chilli samples. This newly developed TLC-PAD is simple and low-cost without any requirement of special instrument or skillful person. The analysis consisted of two steps, i.e., extraction of capsaicinoids from chilli samples by using ethanol as solvent and separation of capsaicinoids by thin-layer chromatography (TLC) and elution of capsaicinoids from the TLC plate with in situ colorimetric detection of capsaicinoids on the PAD. For colorimetric detection, Folin-Ciocalteu reagent was used to detect phenolic functional group of capsaicinoids yielding the blue color. The blue color on the PAD was imaged by a scanner followed by evaluation of its grayscale intensity value by ImageJ program. This newly developed TLC-PAD method provided a linear range from 50 to 1000mgL -1 capsaicinoids with the limit of detection as low as 50mgL -1 capsaicinoids. The proposed method was applied to determine capsaicinoids in dried chilli and seasoning powder samples and the results were in good agreement with those obtained by HPLC method. Copyright © 2016 Elsevier B.V. All rights reserved.
Analytic Neutrino Oscillation Probabilities in Matter: Revisited
DOE Office of Scientific and Technical Information (OSTI.GOV)
Parke, Stephen J.; Denton, Peter B.; Minakata, Hisakazu
2018-01-02
We summarize our recent paper on neutrino oscillation probabilities in matter, explaining the importance, relevance and need for simple, highly accurate approximations to the neutrino oscillation probabilities in matter.
NASA Astrophysics Data System (ADS)
Yahaya, NZ; Ramli, MR; Razak, NNANA; Abbas, Z.
2018-04-01
The Finite Element Method, FEM has been successfully used to model a simple rectangular microstrip sensor to determine the moisture content of Hevea rubber latex. The FEM simulation of sensor and samples was implemented by using COMSOL Multiphysics software. The simulation includes the calculation of magnitude and phase of reflection coefficient and was compared to analytical method. The results show a good agreement in finding the magnitude and phase of reflection coefficient when compared with analytical results. Field distributions of both the unloaded sensor as well as the sensor loaded with different percentages of moisture content were visualized using FEM in conjunction with COMSOL software. The higher the amount of moisture content in the sample the more the electric loops were observed.
NASA Astrophysics Data System (ADS)
El-Nashar, Hassan F.
2017-06-01
We consider a system of three nonidentical coupled phase oscillators in a ring topology. We explore the conditions that must be satisfied in order to obtain the phases at the transition to a synchrony state. These conditions lead to the correct mathematical expressions of phases that aid to find a simple analytic formula for critical coupling when the oscillators transit to a synchronization state having a common frequency value. The finding of a simple expression for the critical coupling allows us to perform a linear stability analysis at the transition to the synchronization stage. The obtained analytic forms of the eigenvalues show that the three coupled phase oscillators with periodic boundary conditions transit to a synchrony state when a saddle-node bifurcation occurs.
Qualitative methods in quantum theory
DOE Office of Scientific and Technical Information (OSTI.GOV)
Migdal, A.B.
The author feels that the solution of most problems in theoretical physics begins with the application of qualitative methods - dimensional estimates and estimates made from simple models, the investigation of limiting cases, the use of the analytic properties of physical quantities, etc. This book proceeds in this spirit, rather than in a formal, mathematical way with no traces of the sweat involved in the original work left to show. The chapters are entitled Dimensional and model approximations, Various types of perturbation theory, The quasi-classical approximation, Analytic properties of physical quantities, Methods in the many-body problem, and Qualitative methods inmore » quantum field theory. Each chapter begins with a detailed introduction, in which the physical meaning of the results obtained in that chapter is explained in a simple way. 61 figures. (RWR)« less
Prediction of thermal cycling induced matrix cracking
NASA Technical Reports Server (NTRS)
Mcmanus, Hugh L.
1992-01-01
Thermal fatigue has been observed to cause matrix cracking in laminated composite materials. A method is presented to predict transverse matrix cracks in composite laminates subjected to cyclic thermal load. Shear lag stress approximations and a simple energy-based fracture criteria are used to predict crack densities as a function of temperature. Prediction of crack densities as a function of thermal cycling is accomplished by assuming that fatigue degrades the material's inherent resistance to cracking. The method is implemented as a computer program. A simple experiment provides data on progressive cracking of a laminate with decreasing temperature. Existing data on thermal fatigue is also used. Correlations of the analytical predictions to the data are very good. A parametric study using the analytical method is presented which provides insight into material behavior under cyclical thermal loads.
A Two-Variable Grading Scheme.
ERIC Educational Resources Information Center
Applebaum, David C.
1979-01-01
Explains a flexible two-part grading scheme which attempts to mix the best of both the descriptive and analytical treatments of an introductory astronomy course, to allow for differences in the academic backgrounds of the students. (GA)
Deep Space Telecommunications Systems Engineering
NASA Technical Reports Server (NTRS)
Yuen, J. H. (Editor)
1982-01-01
Descriptive and analytical information useful for the optimal design, specification, and performance evaluation of deep space telecommunications systems is presented. Telemetry, tracking, and command systems, receiver design, spacecraft antennas, frequency selection, interference, and modulation techniques are addressed.
Preliminary Description of Stresses in Railroad Rail
DOT National Transportation Integrated Search
1976-11-01
One portion of the Federal Railroad Administration's (FRA) Track Performance Improvement Program is the development of engineering and analytic techniques required for the design and maintenance of railroad track of increased integrity and safety. Un...
77 FR 73694 - Privacy Act of 1974: Update Existing System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-11
... survey response, and in the production of summary descriptive statistics and analytical studies in... participation in an agency's Upward Mobility Program or other personnel program designed to broaden an employee...
Analytical, Numerical, and Experimental Results on Turbulent Boundary Layers
1976-07-01
a pitot pressure rake where the spacing between probe centers was 0.5 in. near the wall and 1.0 in. away from the wall. Recently, measurements have...Pressure Gradient, Part II. Analysis- of the Experimental Data." BRL R 1543, June 1971. 51. Allen, J. M. " Pitot -Probe Displacement in a Supersonic Turbulent...numbers; (4) a description of the data reduction of pitot pressure measurements utilizing these analytical results in order to obtain velocity
PAUSE: Predictive Analytics Using SPARQL-Endpoints
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sukumar, Sreenivas R; Ainsworth, Keela; Bond, Nathaniel
2014-07-11
This invention relates to the medical industry and more specifically to methods of predicting risks. With the impetus towards personalized and evidence-based medicine, the need for a framework to analyze/interpret quantitative measurements (blood work, toxicology, etc.) with qualitative descriptions (specialist reports after reading images, bio-medical knowledgebase, etc.) to predict diagnostic risks is fast emerging. We describe a software solution that leverages hardware for scalable in-memory analytics and applies next-generation semantic query tools on medical data.
Numerical and analytical bounds on threshold error rates for hypergraph-product codes
NASA Astrophysics Data System (ADS)
Kovalev, Alexey A.; Prabhakar, Sanjay; Dumer, Ilya; Pryadko, Leonid P.
2018-06-01
We study analytically and numerically decoding properties of finite-rate hypergraph-product quantum low density parity-check codes obtained from random (3,4)-regular Gallager codes, with a simple model of independent X and Z errors. Several nontrivial lower and upper bounds for the decodable region are constructed analytically by analyzing the properties of the homological difference, equal minus the logarithm of the maximum-likelihood decoding probability for a given syndrome. Numerical results include an upper bound for the decodable region from specific heat calculations in associated Ising models and a minimum-weight decoding threshold of approximately 7 % .
Effect of particle inertia on turbulence in a suspension.
L'vov, Victor S; Ooms, Gijs; Pomyalov, Anna
2003-04-01
We propose a one-fluid analytical model for a turbulently flowing dilute suspension, based on a modified Navier-Stokes equation with a k-dependent effective density of suspension rho(eff)(k) and an additional damping term proportional, variant gamma(p)(k), representing the fluid-particle friction (described by Stokes law). The statistical description of turbulence within the model is simplified by a modification of the usual closure procedure based on the Richardson-Kolmogorov picture of turbulence with a differential approximation for the energy transfer term. The resulting ordinary differential equation for the energy budget is solved analytically for various important limiting cases and numerically in the general case. In the inertial interval of scales, we describe analytically two competing effects: the energy suppression due to the fluid-particle friction and the energy enhancement during the cascade process due to decrease of the effective density of the small-scale motions. An additional suppression or enhancement of the energy density may occur in the viscous subrange, caused by the variation of the extent of the inertial interval due to the combined effect of the fluid-particle friction and the decrease of the kinematic viscosity of the suspensions. The analytical description of the complicated interplay of these effects supported by numerical calculations is presented. Our findings allow one to rationalize the qualitative picture of the isotropic homogeneous turbulence of dilute suspensions as observed in direct numerical simulations.
Post-analytical Issues in Hemostasis and Thrombosis Testing.
Favaloro, Emmanuel J; Lippi, Giuseppe
2017-01-01
Analytical concerns within hemostasis and thrombosis testing are continuously decreasing. This is essentially attributable to modern instrumentation, improvements in test performance and reliability, as well as the application of appropriate internal quality control and external quality assurance measures. Pre-analytical issues are also being dealt with in some newer instrumentation, which are able to detect hemolysis, icteria and lipemia, and, in some cases, other issues related to sample collection such as tube under-filling. Post-analytical issues are generally related to appropriate reporting and interpretation of test results, and these are the focus of the current overview, which provides a brief description of these events, as well as guidance for their prevention or minimization. In particular, we propose several strategies for improved post-analytical reporting of hemostasis assays and advise that this may provide the final opportunity to prevent serious clinical errors in diagnosis.
Nonlinear estimation for arrays of chemical sensors
NASA Astrophysics Data System (ADS)
Yosinski, Jason; Paffenroth, Randy
2010-04-01
Reliable detection of hazardous materials is a fundamental requirement of any national security program. Such materials can take a wide range of forms including metals, radioisotopes, volatile organic compounds, and biological contaminants. In particular, detection of hazardous materials in highly challenging conditions - such as in cluttered ambient environments, where complex collections of analytes are present, and with sensors lacking specificity for the analytes of interest - is an important part of a robust security infrastructure. Sophisticated single sensor systems provide good specificity for a limited set of analytes but often have cumbersome hardware and environmental requirements. On the other hand, simple, broadly responsive sensors are easily fabricated and efficiently deployed, but such sensors individually have neither the specificity nor the selectivity to address analyte differentiation in challenging environments. However, arrays of broadly responsive sensors can provide much of the sensitivity and selectivity of sophisticated sensors but without the substantial hardware overhead. Unfortunately, arrays of simple sensors are not without their challenges - the selectivity of such arrays can only be realized if the data is first distilled using highly advanced signal processing algorithms. In this paper we will demonstrate how the use of powerful estimation algorithms, based on those commonly used within the target tracking community, can be extended to the chemical detection arena. Herein our focus is on algorithms that not only provide accurate estimates of the mixture of analytes in a sample, but also provide robust measures of ambiguity, such as covariances.
ERIC Educational Resources Information Center
Harper, Roosevelt
2014-01-01
This research study examined the specific categories of IT control deficiencies and their related effects on financial reporting. The approach to this study was considered non-experimental, an approach sometimes called descriptive. Descriptive statistics are used to describe the basic features of the data in a study, providing simple summaries…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tanizaki, Yuya; Nishimura, Hiromichi; Verbaarschot, Jacobus J. M.
We propose new gradient flows that define Lefschetz thimbles and do not blow up in a finite flow time. Here, we study analytic properties of these gradient flows, and confirm them by numerical tests in simple examples.
Analytical and multibody modeling for the power analysis of standing jumps.
Palmieri, G; Callegari, M; Fioretti, S
2015-01-01
Two methods for the power analysis of standing jumps are proposed and compared in this article. The first method is based on a simple analytical formulation which requires as input the coordinates of the center of gravity in three specified instants of the jump. The second method is based on a multibody model that simulates the jumps processing the data obtained by a three-dimensional (3D) motion capture system and the dynamometric measurements obtained by the force platforms. The multibody model is developed with OpenSim, an open-source software which provides tools for the kinematic and dynamic analyses of 3D human body models. The study is focused on two of the typical tests used to evaluate the muscular activity of lower limbs, which are the counter movement jump and the standing long jump. The comparison between the results obtained by the two methods confirms that the proposed analytical formulation is correct and represents a simple tool suitable for a preliminary analysis of total mechanical work and the mean power exerted in standing jumps.
Analytically tractable climate-carbon cycle feedbacks under 21st century anthropogenic forcing
NASA Astrophysics Data System (ADS)
Lade, Steven J.; Donges, Jonathan F.; Fetzer, Ingo; Anderies, John M.; Beer, Christian; Cornell, Sarah E.; Gasser, Thomas; Norberg, Jon; Richardson, Katherine; Rockström, Johan; Steffen, Will
2018-05-01
Changes to climate-carbon cycle feedbacks may significantly affect the Earth system's response to greenhouse gas emissions. These feedbacks are usually analysed from numerical output of complex and arguably opaque Earth system models. Here, we construct a stylised global climate-carbon cycle model, test its output against comprehensive Earth system models, and investigate the strengths of its climate-carbon cycle feedbacks analytically. The analytical expressions we obtain aid understanding of carbon cycle feedbacks and the operation of the carbon cycle. Specific results include that different feedback formalisms measure fundamentally the same climate-carbon cycle processes; temperature dependence of the solubility pump, biological pump, and CO2 solubility all contribute approximately equally to the ocean climate-carbon feedback; and concentration-carbon feedbacks may be more sensitive to future climate change than climate-carbon feedbacks. Simple models such as that developed here also provide workbenches
for simple but mechanistically based explorations of Earth system processes, such as interactions and feedbacks between the planetary boundaries, that are currently too uncertain to be included in comprehensive Earth system models.
A predictive analytic model for the solar modulation of cosmic rays
Cholis, Ilias; Hooper, Dan; Linden, Tim
2016-02-23
An important factor limiting our ability to understand the production and propagation of cosmic rays pertains to the effects of heliospheric forces, commonly known as solar modulation. The solar wind is capable of generating time- and charge-dependent effects on the spectrum and intensity of low-energy (≲10 GeV) cosmic rays reaching Earth. Previous analytic treatments of solar modulation have utilized the force-field approximation, in which a simple potential is adopted whose amplitude is selected to best fit the cosmic-ray data taken over a given period of time. Making use of recently available cosmic-ray data from the Voyager 1 spacecraft, along withmore » measurements of the heliospheric magnetic field and solar wind, we construct a time-, charge- and rigidity-dependent model of solar modulation that can be directly compared to data from a variety of cosmic-ray experiments. Here, we provide a simple analytic formula that can be easily utilized in a variety of applications, allowing us to better predict the effects of solar modulation and reduce the number of free parameters involved in cosmic-ray propagation models.« less
Analytical study of the critical behavior of the nonlinear pendulum
NASA Astrophysics Data System (ADS)
Lima, F. M. S.
2010-11-01
The dynamics of a simple pendulum consisting of a small bob and a massless rigid rod has three possible regimes depending on its total energy E: Oscillatory (when E is not enough for the pendulum to reach the top position), "perpetual ascent" when E is exactly the energy needed to reach the top, and nonoscillatory for greater energies. In the latter regime, the pendulum rotates periodically without velocity inversions. In contrast to the oscillatory regime, for which an exact analytic solution is known, the other two regimes are usually studied by solving the equation of motion numerically. By applying conservation of energy, I derive exact analytical solutions to both the perpetual ascent and nonoscillatory regimes and an exact expression for the pendulum period in the nonoscillatory regime. Based on Cromer's approximation for the large-angle pendulum period, I find a simple approximate expression for the decrease of the period with the initial velocity in the nonoscillatory regime, valid near the critical velocity. This expression is used to study the critical slowing down, which is observed near the transition between the oscillatory and nonoscillatory regimes.
Parra-Robles, J; Ajraoui, S; Deppe, M H; Parnell, S R; Wild, J M
2010-06-01
Models of lung acinar geometry have been proposed to analytically describe the diffusion of (3)He in the lung (as measured with pulsed gradient spin echo (PGSE) methods) as a possible means of characterizing lung microstructure from measurement of the (3)He ADC. In this work, major limitations in these analytical models are highlighted in simple diffusion weighted experiments with (3)He in cylindrical models of known geometry. The findings are substantiated with numerical simulations based on the same geometry using finite difference representation of the Bloch-Torrey equation. The validity of the existing "cylinder model" is discussed in terms of the physical diffusion regimes experienced and the basic reliance of the cylinder model and other ADC-based approaches on a Gaussian diffusion behaviour is highlighted. The results presented here demonstrate that physical assumptions of the cylinder model are not valid for large diffusion gradient strengths (above approximately 15 mT/m), which are commonly used for (3)He ADC measurements in human lungs. (c) 2010 Elsevier Inc. All rights reserved.
Zor, Erhan; Morales-Narváez, Eden; Zamora-Gálvez, Alejandro; Bingol, Haluk; Ersoz, Mustafa; Merkoçi, Arben
2015-09-16
Due to their size and difficulty to obtain, cost/effective biological or synthetic receptors (e.g., antibodies or aptamers, respectively), organic toxic compounds (e.g., less than 1 kDa) are generally challenging to detect using simple platforms such as biosensors. This study reports on the synthesis and characterization of a novel multifunctional composite material, magnetic silica beads/graphene quantum dots/molecularly imprinted polypyrrole (mSGP). mSGP is engineered to specifically and effectively capture and signal small molecules due to the synergy among chemical, magnetic, and optical properties combined with molecular imprinting of tributyltin (291 Da), a hazardous compound, selected as a model analyte. Magnetic and selective properties of the mSGP composite can be exploited to capture and preconcentrate the analyte onto its surface, and its photoluminescent graphene quantum dots, which are quenched upon analyte recognition, are used to interrogate the presence of the contaminant. This multifunctional material enables a rapid, simple and sensitive platform for small molecule detection, even in complex mediums such as seawater, without any sample treatment.
AN ANALYTIC MODEL OF DUSTY, STRATIFIED, SPHERICAL H ii REGIONS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rodríguez-Ramírez, J. C.; Raga, A. C.; Lora, V.
2016-12-20
We study analytically the effect of radiation pressure (associated with photoionization processes and with dust absorption) on spherical, hydrostatic H ii regions. We consider two basic equations, one for the hydrostatic balance between the radiation-pressure components and the gas pressure, and another for the balance among the recombination rate, the dust absorption, and the ionizing photon rate. Based on appropriate mathematical approximations, we find a simple analytic solution for the density stratification of the nebula, which is defined by specifying the radius of the external boundary, the cross section of dust absorption, and the luminosity of the central star. Wemore » compare the analytic solution with numerical integrations of the model equations of Draine, and find a wide range of the physical parameters for which the analytic solution is accurate.« less
NASA Technical Reports Server (NTRS)
Sulyma, P. R.; Mcanally, J. V.
1975-01-01
The streamline divergence program was developed to demonstrate the capability to trace inviscid surface streamlines and to calculate outflow-corrected laminar and turbulent convective heating rates on surfaces subjected to exhaust plume impingement. The analytical techniques used in formulating this program are discussed. A brief description of the streamline divergence program is given along with a user's guide. The program input and output for a sample case are also presented.
The attentional drift-diffusion model extends to simple purchasing decisions.
Krajbich, Ian; Lu, Dingchao; Camerer, Colin; Rangel, Antonio
2012-01-01
How do we make simple purchasing decisions (e.g., whether or not to buy a product at a given price)? Previous work has shown that the attentional drift-diffusion model (aDDM) can provide accurate quantitative descriptions of the psychometric data for binary and trinary value-based choices, and of how the choice process is guided by visual attention. Here we extend the aDDM to the case of purchasing decisions, and test it using an eye-tracking experiment. We find that the model also provides a reasonably accurate quantitative description of the relationship between choice, reaction time, and visual fixations using parameters that are very similar to those that best fit the previous data. The only critical difference is that the choice biases induced by the fixations are about half as big in purchasing decisions as in binary choices. This suggests that a similar computational process is used to make binary choices, trinary choices, and simple purchasing decisions.
The Attentional Drift-Diffusion Model Extends to Simple Purchasing Decisions
Krajbich, Ian; Lu, Dingchao; Camerer, Colin; Rangel, Antonio
2012-01-01
How do we make simple purchasing decisions (e.g., whether or not to buy a product at a given price)? Previous work has shown that the attentional drift-diffusion model (aDDM) can provide accurate quantitative descriptions of the psychometric data for binary and trinary value-based choices, and of how the choice process is guided by visual attention. Here we extend the aDDM to the case of purchasing decisions, and test it using an eye-tracking experiment. We find that the model also provides a reasonably accurate quantitative description of the relationship between choice, reaction time, and visual fixations using parameters that are very similar to those that best fit the previous data. The only critical difference is that the choice biases induced by the fixations are about half as big in purchasing decisions as in binary choices. This suggests that a similar computational process is used to make binary choices, trinary choices, and simple purchasing decisions. PMID:22707945
Internal quality assurance in diagnostic microbiology: A simple approach for insightful data
Scherz, Valentin; Durussel, Christian
2017-01-01
Given the importance of microbiology results on patient care, high quality standards are expected. Internal quality assurance (IQA) could mitigate the limitations of internal quality control, competency assessment and external quality assurance, adding a longitudinal insight, including pre- and post-analytical steps. Here, we implemented an IQA program in our clinical microbiology facilities with blind resubmission of routine samples during 22 months. One-hundred-and-twenty-one out of 123 (98.4%) serological analyses and 112 out of 122 (91.8%) molecular analyses were concordant. Among the discordances in molecular biology analyses, 6 results were low positive samples that turned out negative, likely due to stochastic repartition of nucleic acids. Moreover, one identified retranscription error led us to implement automated results transmission from the Applied Biosystems instruments to the laboratory information system (LIS). Regarding Gram stain microscopy, 560 out of 745 (75.2%) of compared parameters were concordant. As many as 67 out of 84 (79.8%) pairs of culture results were similar, including 16 sterile pairs, 27 having identical identification or description and semi-quantification and 24 only showing variations in semi-quantification with identical description or identification of colonies. Seventeen pairs had diverging identification or description of colonies. Culture was twice only done for one member of the pairs. Regarding antibiotic susceptibility testing, a major discrepancy was observed in 5 out of 48 results (10.4%). In conclusion, serological tests were highly reproducible. Molecular diagnosis also revealed to be robust except when the amounts of nucleic acids present in the sample were close to the limits of detection. Conventional microbiology was less robust with major discrepancies reaching 39.5% of the samples for microscopy. Similarly, culture and antibiotic susceptibility testing were prone to discrepancies. This work was ground for reconsidering multiples aspects of our practices and demonstrates the importance of IQA to complete the other quality management procedures. PMID:29135992
Internal quality assurance in diagnostic microbiology: A simple approach for insightful data.
Scherz, Valentin; Durussel, Christian; Greub, Gilbert
2017-01-01
Given the importance of microbiology results on patient care, high quality standards are expected. Internal quality assurance (IQA) could mitigate the limitations of internal quality control, competency assessment and external quality assurance, adding a longitudinal insight, including pre- and post-analytical steps. Here, we implemented an IQA program in our clinical microbiology facilities with blind resubmission of routine samples during 22 months. One-hundred-and-twenty-one out of 123 (98.4%) serological analyses and 112 out of 122 (91.8%) molecular analyses were concordant. Among the discordances in molecular biology analyses, 6 results were low positive samples that turned out negative, likely due to stochastic repartition of nucleic acids. Moreover, one identified retranscription error led us to implement automated results transmission from the Applied Biosystems instruments to the laboratory information system (LIS). Regarding Gram stain microscopy, 560 out of 745 (75.2%) of compared parameters were concordant. As many as 67 out of 84 (79.8%) pairs of culture results were similar, including 16 sterile pairs, 27 having identical identification or description and semi-quantification and 24 only showing variations in semi-quantification with identical description or identification of colonies. Seventeen pairs had diverging identification or description of colonies. Culture was twice only done for one member of the pairs. Regarding antibiotic susceptibility testing, a major discrepancy was observed in 5 out of 48 results (10.4%). In conclusion, serological tests were highly reproducible. Molecular diagnosis also revealed to be robust except when the amounts of nucleic acids present in the sample were close to the limits of detection. Conventional microbiology was less robust with major discrepancies reaching 39.5% of the samples for microscopy. Similarly, culture and antibiotic susceptibility testing were prone to discrepancies. This work was ground for reconsidering multiples aspects of our practices and demonstrates the importance of IQA to complete the other quality management procedures.
A nonaffine network model for elastomers undergoing finite deformations
NASA Astrophysics Data System (ADS)
Davidson, Jacob D.; Goulbourne, N. C.
2013-08-01
In this work, we construct a new physics-based model of rubber elasticity to capture the strain softening, strain hardening, and deformation-state dependent response of rubber materials undergoing finite deformations. This model is unique in its ability to capture large-stretch mechanical behavior with parameters that are connected to the polymer chemistry and can also be easily identified with the important characteristics of the macroscopic stress-stretch response. The microscopic picture consists of two components: a crosslinked network of Langevin chains and an entangled network with chains confined to a nonaffine tube. These represent, respectively, changes in entropy due to thermally averaged chain conformations and changes in entropy due to the magnitude of these conformational fluctuations. A simple analytical form for the strain energy density is obtained using Rubinstein and Panyukov's single-chain description of network behavior. The model only depends on three parameters that together define the initial modulus, extent of strain softening, and the onset of strain hardening. Fits to large stretch data for natural rubber, silicone rubber, VHB 4905 (polyacrylate rubber), and b186 rubber (a carbon black-filled rubber) are presented, and a comparison is made with other similar constitutive models of large-stretch rubber elasticity. We demonstrate that the proposed model provides a complete description of elastomers undergoing large deformations for different applied loading configurations. Moreover, since the strain energy is obtained using a clear set of physical assumptions, this model may be tested and used to interpret the results of computer simulation and experiments on polymers of known microscopic structure.
Coping methods to stress among patients on hemodialysis and peritoneal dialysis.
Parvan, Kobra; Ahangar, Ronak; Hosseini, Fahimeh Alsadat; Abdollahzadeh, Farahnaz; Ghojazadeh, Morteza; Jasemi, Madineh
2015-03-01
Dialysis patients need to deal and cope with various aspects of their disease. Identifying the adaptation methods provides valuable information for planning specific treatment and medical care delivery and improving the performance of medical teams. The present study aims to evaluate the coping strategies to stress among patients undergoing hemodialysis (HD) and peritoneal dialysis (PD) at the Imam Reza Educational-Medical Hospital, Tabriz, West Azarbaijan, Iran. This descriptive and analytical study was conducted on 70 patients in the year 2012. The subjects were selected through census method and simple random sampling method. Data were collected using a customized questionnaire and consisted of demographic information and the Jalowiec Coping Scale (JCS) through a structured interview. Descriptive and inferential statistics were used to analyze the data in SPSS (version 13). The mean score of frequency of use of the coping strategy as "sometimes used" for the HD patients was 70.94 ± 18.91 and also for PD patients as "seldom used" was 58.70 ± 12.66. The mean score of helpfulness of coping strategies in the HD group was 49.57 ± 19.42 as "slightly helpful", whereas in the PD group it was 37.21 ± 14.38 as "slightly helpful" Furthermore, both groups used the emotion-oriented coping styles more frequently than the problem-oriented methods. HD patients used coping methods more frequently than the PD patients. The majority of patients used emotion-oriented coping strategies to deal with stress factors. Use of educational, counseling and supportive programs to assist in coping techniques can facilitate the coping process with stress factors in dialysis patients.
Project Management in NASA: The system and the men
NASA Technical Reports Server (NTRS)
Pontious, R. H.; Barnes, L. B.
1973-01-01
An analytical description of the NASA project management system is presented with emphasis on the human element. The NASA concept of project management, program managers, and the problems and strengths of the NASA system are discussed.
Projectiles, pendula, and special relativity
NASA Astrophysics Data System (ADS)
Price, Richard H.
2005-05-01
The kind of flat-earth gravity used in introductory physics appears in an accelerated reference system in special relativity. From this viewpoint, we work out the special relativistic description of a ballistic projectile and a simple pendulum, two examples of simple motion driven by earth-surface gravity. The analysis uses only the basic mathematical tools of special relativity typical of a first-year university course.
Developing an Emergency Physician Productivity Index Using Descriptive Health Analytics.
Khalifa, Mohamed
2015-01-01
Emergency department (ED) crowding became a major barrier to receiving timely emergency care. At King Faisal Specialist Hospital and Research Center, Saudi Arabia, we identified variables and factors affecting crowding and performance to develop indicators to help evaluation and improvement. Measuring efficiency of work and activity of throughput processes; it was important to develop an ED physician productivity index. Data on all ED patients' encounters over the last six months of 2014 were retrieved and descriptive health analytics methods were used. Three variables were identified for their influence on productivity and performance; Number of Treated Patients per Physician, Patient Acuity Level and Treatment Time. The study suggested a formula to calculate the productivity index of each physician through dividing the Number of Treated Patients by Patient Acuity Level squared and Treatment Time to identify physicians with low productivity index and investigate causes and factors.
Classical Dynamics of Fullerenes
NASA Astrophysics Data System (ADS)
Sławianowski, Jan J.; Kotowski, Romuald K.
2017-06-01
The classical mechanics of large molecules and fullerenes is studied. The approach is based on the model of collective motion of these objects. The mixed Lagrangian (material) and Eulerian (space) description of motion is used. In particular, the Green and Cauchy deformation tensors are geometrically defined. The important issue is the group-theoretical approach to describing the affine deformations of the body. The Hamiltonian description of motion based on the Poisson brackets methodology is used. The Lagrange and Hamilton approaches allow us to formulate the mechanics in the canonical form. The method of discretization in analytical continuum theory and in classical dynamics of large molecules and fullerenes enable us to formulate their dynamics in terms of the polynomial expansions of configurations. Another approach is based on the theory of analytical functions and on their approximations by finite-order polynomials. We concentrate on the extremely simplified model of affine deformations or on their higher-order polynomial perturbations.
Artemyev, A V; Neishtadt, A I; Zelenyi, L M; Vainchtein, D L
2010-12-01
We present an analytical and numerical study of the surfatron acceleration of nonrelativistic charged particles by electromagnetic waves. The acceleration is caused by capture of particles into resonance with one of the waves. We investigate capture for systems with one or two waves and provide conditions under which the obtained results can be applied to systems with more than two waves. In the case of a single wave, the once captured particles never leave the resonance and their velocity grows linearly with time. However, if there are two waves in the system, the upper bound of the energy gain may exist and we find the analytical value of that bound. We discuss several generalizations including the relativistic limit, different wave amplitudes, and a wide range of the waves' wavenumbers. The obtained results are used for qualitative description of some phenomena observed in the Earth's magnetosphere. © 2010 American Institute of Physics.
The Use and Abuse of Limits of Detection in Environmental Analytical Chemistry
Brown, Richard J. C.
2008-01-01
The limit of detection (LoD) serves as an important method performance measure that is useful for the comparison of measurement techniques and the assessment of likely signal to noise performance, especially in environmental analytical chemistry. However, the LoD is only truly related to the precision characteristics of the analytical instrument employed for the analysis and the content of analyte in the blank sample. This article discusses how other criteria, such as sampling volume, can serve to distort the quoted LoD artificially and make comparison between various analytical methods inequitable. In order to compare LoDs between methods properly, it is necessary to state clearly all of the input parameters relating to the measurements that have been used in the calculation of the LoD. Additionally, the article discusses that the use of LoDs in contexts other than the comparison of the attributes of analytical methods, in particular when reporting analytical results, may be confusing, less informative than quoting the actual result with an accompanying statement of uncertainty, and may act to bias descriptive statistics. PMID:18690384
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ekechukwu, A.
This document proposes to provide a listing of available sources which can be used to validate analytical methods and/or instrumentation for beryllium determination. A literature review was conducted of available standard methods and publications used for method validation and/or quality control. A comprehensive listing of the articles, papers, and books reviewed is given in Appendix 1. Available validation documents and guides are listed in the appendix; each has a brief description of application and use. In the referenced sources, there are varying approaches to validation and varying descriptions of validation at different stages in method development. This discussion focuses onmore » validation and verification of fully developed methods and instrumentation that have been offered up for use or approval by other laboratories or official consensus bodies such as ASTM International, the International Standards Organization (ISO) and the Association of Official Analytical Chemists (AOAC). This review was conducted as part of a collaborative effort to investigate and improve the state of validation for measuring beryllium in the workplace and the environment. Documents and publications from the United States and Europe are included. Unless otherwise specified, all documents were published in English.« less
ERIC Educational Resources Information Center
Edwards, Mark Evan; Weber, Bruce; Bernell, Stephanie
2007-01-01
An existing measure of food insecurity with hunger in the United States may serve as an effective indicator of quality of life. State level differences in that measure can reveal important differences in quality of life across places. In this study, we advocate and demonstrate two simple methods by which analysts can explore state-specific…
NASA Astrophysics Data System (ADS)
Nakwaski, W.
1988-11-01
An analysis is made of the thermal conductivity of quaternary solid solutions (alloys) allowing for their disordered structure on the basis of a phenomenological analysis proposed by Abeles. This method is applied to a quaternary solid solution In1 - xGaxAsyP1 - y. A simple analytic expression is derived for the thermal conductivity of this material.
Biktashev, Vadim N
2014-04-01
We consider a simple mathematical model of gradual Darwinian evolution in continuous time and continuous trait space, due to intraspecific competition for common resource in an asexually reproducing population in constant environment, while far from evolutionary stable equilibrium. The model admits exact analytical solution. In particular, Gaussian distribution of the trait emerges from generic initial conditions.
Simple apparatus for polarization sensing of analytes
NASA Astrophysics Data System (ADS)
Gryczynski, Zygmunt; Gryczynski, Ignacy; Lakowicz, Joseph R.
2000-09-01
We describe a simple device for fluorescence sensing based on an unexpansive light source, a dual photocell and a Watson bridge. The emission is detected from two fluorescent samples, one of which changes intensity in response to the analyte. The emission from these two samples is observed through two orthogonally oriented polarizers and an analyzer polarizer. The latter polarizer is rotated to yield equal intensities from both sides of the dual photocell, as determined by a zero voltage from the Watson bridge. Using this device, we are able to measure fluorescein concentration to an accuracy near 2% at 1 (mu) M fluorescein, and pH values accurate to +/- 0.02 pH units. We also use this approach with a UV hand lamp and a glucose-sensitive protein to measure glucose concentrations near 2 (mu) M to an accuracy of +/- 0.1 (mu) M. This approach requires only simple electronics, which can be battery powered. Additionally, the method is generic, and can be applied with any fluorescent sample that displays a change in intensity. One can imagine this approach being used to develop portable point-of-care clinical devices.
Huertas-Pérez, José Fernando; Arroyo-Manzanares, Natalia; Hitzler, Dominik; Castro-Guerrero, Francisco Germán; Gámiz-Gracia, Laura; García-Campaña, Ana M
2018-04-15
A fast and simple analytical method was developed and characterized for the determination of aflatoxins (B 1 , B 2 , G 1 and G 2 ) in rice. The procedure is based on a simple solid-liquid extraction without further clean-up, and analysis by ultra-high performance liquid chromatography coupled with fluorescence detection. Fluorescence emission of aflatoxins B 1 and G 1 was enhanced by post-column chemical derivatization using pyridinium bromide perbromide. The analytical method was satisfactorily characterized in white and brown rice. Under optimum conditions, external calibration in solvent could be used for quantification purposes and limits of quantification were below the maximum contents established by the European Union regulation for these contaminants/commodity group combination (0.07-0.14 µg/kg for white rice and 0.20-0.28 µg/kg for brown rice). Recovery studies carried out at three different concentration levels (0.5, 2 and 5 µg/kg) showed values in the range of 84.5-105.3%, and RSDs ≤ 5%. Copyright © 2017 Elsevier Ltd. All rights reserved.
Computer Classification of Triangles and Quadrilaterals--A Challenging Application
ERIC Educational Resources Information Center
Dennis, J. Richard
1978-01-01
Two computer exercises involving the classification of geometric figures are given. The mathematics required is relatively simple but comes from several areas--synthetic geometry, analytic geometry, and linear algebra. (MN)
The Earth's Magnetic Field: A Simple Measurement of Its Strength
ERIC Educational Resources Information Center
Chamberlain, William G., III
1978-01-01
This laboratory exercise for junior or senior high school students forms a basis for expansion of concepts, offers opportunities for analytical thinking, and presents possibilities for independent thinking. (BB)
Malá, Zdena; Gebauer, Petr
2017-10-06
Capillary isotachophoresis (ITP) is an electrophoretic technique offering high sensitivity due to permanent stacking of the migrating analytes. Its combination with electrospray-ionization mass-spectrometric (ESI-MS) detection is limited by the narrow spectrum of ESI-compatible components but can be compensated by experienced system architecture. This work describes a methodology for sensitive analysis of hydroxyderivatives of s-triazine herbicides, based on implementation of the concepts of moving-boundary isotachophoresis and of H + as essential terminating component into cationic ITP with ESI-MS detection. Theoretical description of such kind of system is given and equations for zone-related boundary mobilities are derived, resulting in a much more general definition of the effective mobility of the terminating H + zone than used so far. Explicit equations allowing direct calculation for selected simple systems are derived. The presented theory allows prediction of stacking properties of particular systems and easy selection of suitable electrolyte setups. A simple ESI-compatible system composed of acetic acid and ammonium with H + and ammonium as a mixed terminator was selected for the analysis of 2-hydroxyatrazine and 2-hydroxyterbutylazine, degradation products of s-triazine herbicides. The proposed method was tested with direct injection without any sample pretreatment and provided excellent linearity and high sensitivity with limits of detection below 100ng/L (0.5nM). Example analyses of unspiked and spiked drinking and river water are shown. Copyright © 2017 Elsevier B.V. All rights reserved.
Method for the simulation of blood platelet shape and its evolution during activation
Muliukov, Artem R.; Litvinenko, Alena L.; Nekrasov, Vyacheslav M.; Chernyshev, Andrei V.; Maltsev, Valeri P.
2018-01-01
We present a simple physically based quantitative model of blood platelet shape and its evolution during agonist-induced activation. The model is based on the consideration of two major cytoskeletal elements: the marginal band of microtubules and the submembrane cortex. Mathematically, we consider the problem of minimization of surface area constrained to confine the marginal band and a certain cellular volume. For resting platelets, the marginal band appears as a peripheral ring, allowing for the analytical solution of the minimization problem. Upon activation, the marginal band coils out of plane and forms 3D convoluted structure. We show that its shape is well approximated by an overcurved circle, a mathematical concept of closed curve with constant excessive curvature. Possible mechanisms leading to such marginal band coiling are discussed, resulting in simple parametric expression for the marginal band shape during platelet activation. The excessive curvature of marginal band is a convenient state variable which tracks the progress of activation. The cell surface is determined using numerical optimization. The shapes are strictly mathematically defined by only three parameters and show good agreement with literature data. They can be utilized in simulation of platelets interaction with different physical fields, e.g. for the description of hydrodynamic and mechanical properties of platelets, leading to better understanding of platelets margination and adhesion and thrombus formation in blood flow. It would also facilitate precise characterization of platelets in clinical diagnosis, where a novel optical model is needed for the correct solution of inverse light-scattering problem. PMID:29518073
Asay window: A new spall diagnostic
NASA Astrophysics Data System (ADS)
McCluskey, Craig W.; Wilke, Mark D.; Anderson, William W.; Byers, Mark E.; Holtkamp, David B.; Rigg, Paulo A.; Furnish, Michael D.; Romero, Vincent T.
2006-11-01
By changing from the metallic foil of the Asay foil diagnostic, which can detect ejecta from a shocked surface, to a lithium fluoride (LiF) or polymethyl methacrylate (PMMA) window, it is possible to detect multiple spall layers and interlayer rubble. Past experiments to demonstrate this diagnostic have used high explosives (HEs) to shock metals to produce multiple spall layers. Because the exact characteristics of HE-induced spall layers cannot be predetermined, two issues exist in the quantitative interpretation of the data. First, to what level of fidelity is the Asay window method capable of providing quantitative information about spall layers, possibly separated by rubble, and second, contingent on the first, can an analytic technique be developed to convert the data to a meaningful description of spall from a given experiment? In this article, we address the first issue. A layered projectile fired from a gas gun was used to test the new diagnostic's accuracy and repeatability. We impacted a LiF or PMMA window viewed by a velocity interferometer system for any reflector (VISAR) probe with a projectile consisting of four thin stainless steel disks spaced apart 200μm with either vacuum or polyethylene. The window/surface interface velocity measured with a VISAR probe was compared with calculations. The good agreement observed between the adjusted calculation and the measured data indicates that, in principle and given enough prior information, it is possible to use the Asay window data to model a density distribution from spalled material with simple hydrodynamic models and only simple adjustments to nominal predictions.
Major advances in testing of dairy products: milk component and dairy product attribute testing.
Barbano, D M; Lynch, J M
2006-04-01
Milk component analysis is relatively unusual in the field of quantitative analytical chemistry because an analytical test result determines the allocation of very large amounts of money between buyers and sellers of milk. Therefore, there is high incentive to develop and refine these methods to achieve a level of analytical performance rarely demanded of most methods or laboratory staff working in analytical chemistry. In the last 25 yr, well-defined statistical methods to characterize and validate analytical method performance combined with significant improvements in both the chemical and instrumental methods have allowed achievement of improved analytical performance for payment testing. A shift from marketing commodity dairy products to the development, manufacture, and marketing of value added dairy foods for specific market segments has created a need for instrumental and sensory approaches and quantitative data to support product development and marketing. Bringing together sensory data from quantitative descriptive analysis and analytical data from gas chromatography olfactometry for identification of odor-active compounds in complex natural dairy foods has enabled the sensory scientist and analytical chemist to work together to improve the consistency and quality of dairy food flavors.
Validating Analytical Protocols to Determine Selected Pesticides and PCBs Using Routine Samples.
Pindado Jiménez, Oscar; García Alonso, Susana; Pérez Pastor, Rosa María
2017-01-01
This study aims at providing recommendations concerning the validation of analytical protocols by using routine samples. It is intended to provide a case-study on how to validate the analytical methods in different environmental matrices. In order to analyze the selected compounds (pesticides and polychlorinated biphenyls) in two different environmental matrices, the current work has performed and validated two analytical procedures by GC-MS. A description is given of the validation of the two protocols by the analysis of more than 30 samples of water and sediments collected along nine months. The present work also scopes the uncertainty associated with both analytical protocols. In detail, uncertainty of water sample was performed through a conventional approach. However, for the sediments matrices, the estimation of proportional/constant bias is also included due to its inhomogeneity. Results for the sediment matrix are reliable, showing a range 25-35% of analytical variability associated with intermediate conditions. The analytical methodology for the water matrix determines the selected compounds with acceptable recoveries and the combined uncertainty ranges between 20 and 30%. Analyzing routine samples is rarely applied to assess trueness of novel analytical methods and up to now this methodology was not focused on organochlorine compounds in environmental matrices.
Analytical Tools Interface for Landscape Assessments
Environmental management practices are trending away from simple, local-scale assessments toward complex, multiple-stressor regional assessments. Landscape ecology provides the theory behind these assessments while geographic information systems (GIS) supply the tools to implemen...
Matrix Theory of Small Oscillations
ERIC Educational Resources Information Center
Chavda, L. K.
1978-01-01
A complete matrix formulation of the theory of small oscillations is presented. Simple analytic solutions involving matrix functions are found which clearly exhibit the transients, the damping factors, the Breit-Wigner form for resonances, etc. (BB)
fMRI activation patterns in an analytic reasoning task: consistency with EEG source localization
NASA Astrophysics Data System (ADS)
Li, Bian; Vasanta, Kalyana C.; O'Boyle, Michael; Baker, Mary C.; Nutter, Brian; Mitra, Sunanda
2010-03-01
Functional magnetic resonance imaging (fMRI) is used to model brain activation patterns associated with various perceptual and cognitive processes as reflected by the hemodynamic (BOLD) response. While many sensory and motor tasks are associated with relatively simple activation patterns in localized regions, higher-order cognitive tasks may produce activity in many different brain areas involving complex neural circuitry. We applied a recently proposed probabilistic independent component analysis technique (PICA) to determine the true dimensionality of the fMRI data and used EEG localization to identify the common activated patterns (mapped as Brodmann areas) associated with a complex cognitive task like analytic reasoning. Our preliminary study suggests that a hybrid GLM/PICA analysis may reveal additional regions of activation (beyond simple GLM) that are consistent with electroencephalography (EEG) source localization patterns.
Deciphering mRNA Sequence Determinants of Protein Production Rate
NASA Astrophysics Data System (ADS)
Szavits-Nossan, Juraj; Ciandrini, Luca; Romano, M. Carmen
2018-03-01
One of the greatest challenges in biophysical models of translation is to identify coding sequence features that affect the rate of translation and therefore the overall protein production in the cell. We propose an analytic method to solve a translation model based on the inhomogeneous totally asymmetric simple exclusion process, which allows us to unveil simple design principles of nucleotide sequences determining protein production rates. Our solution shows an excellent agreement when compared to numerical genome-wide simulations of S. cerevisiae transcript sequences and predicts that the first 10 codons, which is the ribosome footprint length on the mRNA, together with the value of the initiation rate, are the main determinants of protein production rate under physiological conditions. Finally, we interpret the obtained analytic results based on the evolutionary role of the codons' choice for regulating translation rates and ribosome densities.
A Review of Numerical Simulation and Analytical Modeling for Medical Devices Safety in MRI
Kabil, J.; Belguerras, L.; Trattnig, S.; Pasquier, C.; Missoffe, A.
2016-01-01
Summary Objectives To review past and present challenges and ongoing trends in numerical simulation for MRI (Magnetic Resonance Imaging) safety evaluation of medical devices. Methods A wide literature review on numerical and analytical simulation on simple or complex medical devices in MRI electromagnetic fields shows the evolutions through time and a growing concern for MRI safety over the years. Major issues and achievements are described, as well as current trends and perspectives in this research field. Results Numerical simulation of medical devices is constantly evolving, supported by calculation methods now well-established. Implants with simple geometry can often be simulated in a computational human model, but one issue remaining today is the experimental validation of these human models. A great concern is to assess RF heating on implants too complex to be traditionally simulated, like pacemaker leads. Thus, ongoing researches focus on alternative hybrids methods, both numerical and experimental, with for example a transfer function method. For the static field and gradient fields, analytical models can be used for dimensioning simple implants shapes, but limited for complex geometries that cannot be studied with simplifying assumptions. Conclusions Numerical simulation is an essential tool for MRI safety testing of medical devices. The main issues remain the accuracy of simulations compared to real life and the studies of complex devices; but as the research field is constantly evolving, some promising ideas are now under investigation to take up the challenges. PMID:27830244
Makino, Yukiko
2012-03-01
A simple and sensitive HPLC technique was developed for the qualitative determination of ephedrine and pseudoephedrine (ephedrines), used as precursors of clandestine d-methamphetamine hydrochloride of high purity. Good separation of ephedrines from bulk d-methamphetamine was achieved, without any extraction or derivatization procedure on a CAPCELLPACK C18 MGII (250 × 4.6 mm) column. The mobile phase consisted of 50 mM KH2 PO4-acetonitrile (94:6 v/v %) using an isocratic pump system within 20 min for detecting two analytes. One run took about 50 min as it was necessary to wash out overloaded methamphetamine for column conditioning. The analytes were detected by UV absorbance measurement at 210 nm. A sample (20 mg) was simply dissolved in 1 mL of water, and a 50 μL aliquot of the solution was injected into the HPLC. The detection limits for ephedrine and pseudoephedrine in bulk d-methamphetamine were as low as 3 ppm each. This analytical separation technique made it possible to detect ephedrine and/or pseudoephedrine in seven samples of high-purity d-methamphetamine hydrochloride seized in Japan. The presence of trace ephedrines in illicit methamphetamine may strongly indicate a synthetic route via ephedrine in methamphetamine profiling. This method is simple and sensitive, requiring only commonly available equipment, and should be useful for high-purity methamphetamine profiling. Copyright © 2011 John Wiley & Sons, Ltd.
ERIC Educational Resources Information Center
Maus, Fred Everett
2010-01-01
Philosopher Richard Shusterman's book "Body Consciousness" is the most recent and most extensive addition to Shusterman's project of "somaesthetics," an area of philosophy dealing with experiences of embodiment. Shusterman distinguishes three aspects of somaesthetics. Analytic somaesthetics is a "descriptive and theoretical enterprise"; pragmatic…
40 CFR 79.11 - Information and assurances to be provided by the fuel manufacturer.
Code of Federal Regulations, 2010 CFR
2010-07-01
... description (or identification, in the case of a generally accepted method) of a suitable analytical technique... sold, offered for sale, or introduced into commerce for use in motor vehicles manufactured after model...
General Solution of the Rayleigh Equation for the Description of Bubble Oscillations Near a Wall
NASA Astrophysics Data System (ADS)
Garashchuk, Ivan; Sinelshchikov, Dmitry; Kudryashov, Nikolay
2018-02-01
We consider a generalization of the Rayleigh equation for the description of the dynamics of a spherical gas bubble oscillating near an elastic or rigid wall. We show that in the non-dissipative case, i.e. neglecting the liquid viscosity and compressibility, it is possible to construct the general analytical solution of this equation. The corresponding general solution is expressed via the Weierstrass elliptic function. We analyze the dependence of this solution properties on the physical parameters.
NASA Technical Reports Server (NTRS)
Weller, T.
1977-01-01
The applicability and adequacy of several computer techniques in predicting satisfactorily the nonlinear/inelastic response of angle ply laminates were evaluated. The analytical predictions were correlated with the results of a test program on the inelastic response under axial compression of a large variety of graphite-epoxy and boron-epoxy angle ply laminates. These comparison studies indicate that neither of the abovementioned analyses can satisfactorily predict either the mode of response or the ultimate stress value corresponding to a particular angle ply laminate configuration. Consequently, also the simple failure mechanisms assumed in the analytical models were not verified.
NASA Astrophysics Data System (ADS)
Wu, Peng; Zhang, Yunchang; Lv, Yi; Hou, Xiandeng
2006-12-01
A simple, low cost and highly sensitive method based on cloud point extraction (CPE) for separation/preconcentration and thermospray flame quartz furnace atomic absorption spectrometry was proposed for the determination of ultratrace cadmium in water and urine samples. The analytical procedure involved the formation of analyte-entrapped surfactant micelles by mixing the analyte solution with an ammonium pyrrolidinedithiocarbamate (APDC) solution and a Triton X-114 solution. When the temperature of the system was higher than the cloud point of Triton X-114, the complex of cadmium-PDC entered the surfactant-rich phase and thus separation of the analyte from the matrix was achieved. Under optimal chemical and instrumental conditions, the limit of detection was 0.04 μg/L for cadmium with a sample volume of 10 mL. The analytical results of cadmium in water and urine samples agreed well with those by ICP-MS.
Analytical model for the density distribution in the Io plasma torus
NASA Technical Reports Server (NTRS)
Mei, YI; Thorne, Richard M.; Bagenal, Fran
1995-01-01
An analytical model is developed for the diffusive equilibrium plasma density distribution in the Io plasma torus. The model has been employed successfully to follow the ray path of plasma waves in the multi-ion Jovian magnetosphere; it would also be valuable for other studies of the Io torus that require a smooth and continuous description of the plasma density and its gradients. Validity of the analytical treatment requires that the temperature of thermal electrons be much lower than the ion temperature and that superthermal electrons be much less abundant than the thermal electrons; these two conditions are satisfied in the warm outer region of the Io torus from L = 6 to L = 10. The analytical solutions agree well with exact numerical calculations for the most dense portion of the Io torus within 30 deg of the equator.
Simple Benchmark Specifications for Space Radiation Protection
NASA Technical Reports Server (NTRS)
Singleterry, Robert C. Jr.; Aghara, Sukesh K.
2013-01-01
This report defines space radiation benchmark specifications. This specification starts with simple, monoenergetic, mono-directional particles on slabs and progresses to human models in spacecraft. This report specifies the models and sources needed to what the team performing the benchmark needs to produce in a report. Also included are brief descriptions of how OLTARIS, the NASA Langley website for space radiation analysis, performs its analysis.
Prediction of the thermal environment and thermal response of simple panels exposed to radiant heat
NASA Technical Reports Server (NTRS)
Turner, Travis L.; Ash, Robert L.
1989-01-01
A method of predicting the radiant heat flux distribution produced by a bank of tubular quartz heaters was applied to a radiant system consisting of a single unreflected lamp irradiating a flat metallic incident surface. In this manner, the method was experimentally verified for various radiant system parameter settings and used as a source of input for a finite element thermal analysis. Two finite element thermal analyses were applied to a thermal system consisting of a thin metallic panel exposed to radiant surface heating. A two-dimensional steady-state finite element thermal analysis algorithm, based on Galerkin's Method of Weighted Residuals (GFE), was formulated specifically for this problem and was used in comparison to the thermal analyzers of the Engineering Analysis Language (EAL). Both analyses allow conduction, convection, and radiation boundary conditions. Differences in the respective finite element formulation are discussed in terms of their accuracy and resulting comparison discrepancies. The thermal analyses are shown to perform well for the comparisons presented here with some important precautions about the various boundary condition models. A description of the experiment, corresponding analytical modeling, and resulting comparisons are presented.
NASA Astrophysics Data System (ADS)
Wilson, Robert H.; Vishwanath, Karthik; Mycek, Mary-Ann
2009-02-01
Monte Carlo (MC) simulations are considered the "gold standard" for mathematical description of photon transport in tissue, but they can require large computation times. Therefore, it is important to develop simple and efficient methods for accelerating MC simulations, especially when a large "library" of related simulations is needed. A semi-analytical method involving MC simulations and a path-integral (PI) based scaling technique generated time-resolved reflectance curves from layered tissue models. First, a zero-absorption MC simulation was run for a tissue model with fixed scattering properties in each layer. Then, a closed-form expression for the average classical path of a photon in tissue was used to determine the percentage of time that the photon spent in each layer, to create a weighted Beer-Lambert factor to scale the time-resolved reflectance of the simulated zero-absorption tissue model. This method is a unique alternative to other scaling techniques in that it does not require the path length or number of collisions of each photon to be stored during the initial simulation. Effects of various layer thicknesses and absorption and scattering coefficients on the accuracy of the method will be discussed.
Volterra series truncation and kernel estimation of nonlinear systems in the frequency domain
NASA Astrophysics Data System (ADS)
Zhang, B.; Billings, S. A.
2017-02-01
The Volterra series model is a direct generalisation of the linear convolution integral and is capable of displaying the intrinsic features of a nonlinear system in a simple and easy to apply way. Nonlinear system analysis using Volterra series is normally based on the analysis of its frequency-domain kernels and a truncated description. But the estimation of Volterra kernels and the truncation of Volterra series are coupled with each other. In this paper, a novel complex-valued orthogonal least squares algorithm is developed. The new algorithm provides a powerful tool to determine which terms should be included in the Volterra series expansion and to estimate the kernels and thus solves the two problems all together. The estimated results are compared with those determined using the analytical expressions of the kernels to validate the method. To further evaluate the effectiveness of the method, the physical parameters of the system are also extracted from the measured kernels. Simulation studies demonstrates that the new approach not only can truncate the Volterra series expansion and estimate the kernels of a weakly nonlinear system, but also can indicate the applicability of the Volterra series analysis in a severely nonlinear system case.
Termination of the solar wind in the hot, partially ionized interstellar medium. Ph.D. Thesis
NASA Technical Reports Server (NTRS)
Lombard, C. K.
1974-01-01
Theoretical foundations for understanding the problem of the termination of the solar wind are reexamined in the light of most recent findings concerning the states of the solar wind and the local interstellar medium. The investigation suggests that a simple extention of Parker's (1961) analytical model provides a useful approximate description of the combined solar wind, interstellar wind plasma flowfield under conditions presently thought to occur. A linear perturbation solution exhibiting both the effects of photoionization and charge exchange is obtained for the supersonic solar wind. A numerical algorithm is described for computing moments of the non-equilibrium hydrogen distribution function and associated source terms for the MHD equations. Computed using the algorithm in conjunction with the extended Parker solution to approximate the plasma flowfield, profiles of hydrogen number density are given in the solar wind along the upstream and downstream axes of flow with respect to the direction of the interstellar wind. Predictions of solar Lyman-alpha backscatter intensities to be observed at 1 a.u. have been computed, in turn, from a set of such hydrogen number density profiles varied over assumed conditions of the interstellar wind.
Local structure controls the nonaffine shear and bulk moduli of disordered solids
NASA Astrophysics Data System (ADS)
Schlegel, M.; Brujic, J.; Terentjev, E. M.; Zaccone, A.
2016-01-01
Paradigmatic model systems, which are used to study the mechanical response of matter, are random networks of point-atoms, random sphere packings, or simple crystal lattices; all of these models assume central-force interactions between particles/atoms. Each of these models differs in the spatial arrangement and the correlations among particles. In turn, this is reflected in the widely different behaviours of the shear (G) and compression (K) elastic moduli. The relation between the macroscopic elasticity as encoded in G, K and their ratio, and the microscopic lattice structure/order, is not understood. We provide a quantitative analytical connection between the local orientational order and the elasticity in model amorphous solids with different internal microstructure, focusing on the two opposite limits of packings (strong excluded-volume) and networks (no excluded-volume). The theory predicts that, in packings, the local orientational order due to excluded-volume causes less nonaffinity (less softness or larger stiffness) under compression than under shear. This leads to lower values of G/K, a well-documented phenomenon which was lacking a microscopic explanation. The theory also provides an excellent one-parameter description of the elasticity of compressed emulsions in comparison with experimental data over a broad range of packing fractions.
Sleep Respiratory Disorders and Clinical Profile in Patients with Type 2 Diabetes Mellitus
Fontela, Paula Caitano; Winkelmann, Eliane Roseli; Pretto, Luciana Meggiolaro; Berlezi, Evelise Moraes
2014-01-01
Introduction Sleep respiratory disorders (SRDs) are often found in patients with type 2 diabetes mellitus (T2DM). Objective The aim was to establish the prevalence of risk to develop an SRD using the Clinical Berlin Questionnaire (CBQ) and Epworth Sleepiness Scale (ESS) in patients with T2DM and verifying the correlation of anthropometric measurements and life quality (LQ) with ESS. Methods A descriptive and analytical study of a case series evaluating 208 patients with T2DM, submitted to clinical and biochemical evaluation and implementation of CBQ, ESS, and WHOQOL-bref to evaluate LQ. Results Mean age was 60.8 ± 8.8 years, and 65.4% were women. Most diabetics were overweight (36.1%), and 29.8% were class I obese. One-third had positive risk signals for a SRD, with 87.0 and 34.1% having high risk in CBQ and sleep disorders in ESS, respectively. There was a significant difference in the general LQ between the low- and high-risk groups in the CBQ. Conclusion In this scenario, it is noteworthy that the active search for sleep disorders must start from simple methods, such as application of protocols. PMID:25992154
Experimental and theoretical study of iron and mild steel combustion in oxygen flows
NASA Astrophysics Data System (ADS)
El-Rabii, Hazem; Kazakov, Kirill A.; Muller, Maryse
2017-03-01
The effects of oxygen flow speed and pressure on the iron and mild steel combustion are investigated experimentally and theoretically. The studied specimens are vertical cylindrical rods subjected to an axial oxygen flow and ignited at the upper end by laser irradiation. Three main stages of the combustion process have been identified experimentally: (1) induction period, during which the rod is heated until an intensive metal oxidation begins at its upper end; (2) static combustion, during which a laminar liquid "cap'' slowly grows on the upper rod end, and, after the liquid cap detachment from the sample; (3) dynamic combustion, which is characterized by a rapid metal consumption and turbulent liquid motions. An analytical description of these stages is given. In particular, a model of the dynamic combustion is constructed based on the turbulent oxygen transport through the liquid metal-oxide flow. This model yields a simple expression for the fraction of metal burned in the process and allows one to calculate the normal propagation speed of the solid metal-liquid interface as a function of the oxygen flow speed and pressure. A comparison of the theory with the experimental results is made, and its potential application is mentioned.
[Model of Analysis and Prevention of Accidents - MAPA: tool for operational health surveillance].
de Almeida, Ildeberto Muniz; Vilela, Rodolfo Andrade de Gouveia; da Silva, Alessandro José Nunes; Beltran, Sandra Lorena
2014-12-01
The analysis of work-related accidents is important for accident surveillance and prevention. Current methods of analysis seek to overcome reductionist views that see these occurrences as simple events explained by operator error. The objective of this paper is to analyze the Model of Analysis and Prevention of Accidents (MAPA) and its use in monitoring interventions, duly highlighting aspects experienced in the use of the tool. The descriptive analytical method was used, introducing the steps of the model. To illustrate contributions and or difficulties, cases where the tool was used in the context of service were selected. MAPA integrates theoretical approaches that have already been tried in studies of accidents by providing useful conceptual support from the data collection stage until conclusion and intervention stages. Besides revealing weaknesses of the traditional approach, it helps identify organizational determinants, such as management failings, system design and safety management involved in the accident. The main challenges lie in the grasp of concepts by users, in exploring organizational aspects upstream in the chain of decisions or at higher levels of the hierarchy, as well as the intervention to change the determinants of these events.
Walters, William J; Christensen, Villy
2018-01-01
Ecotracer is a tool in the Ecopath with Ecosim (EwE) software package used to simulate and analyze the transport of contaminants such as methylmercury or radiocesium through aquatic food webs. Ecotracer solves the contaminant dynamic equations simultaneously with the biomass dynamic equations in Ecosim/Ecospace. In this paper, we give a detailed description of the Ecotracer module and analyze the performance on two problems of differing complexity. Ecotracer was modified from previous versions to more accurately model contaminant excretion, and new numerical integration algorithms were implemented to increase accuracy and robustness. To test the mathematical robustness of the computational algorithm, Ecotracer was tested on a simple problem for which we know an analytical solution. These results demonstrated the effectiveness of the program numerics. A much more complex model, the release of the cesium radionuclide 137 Cs from the Fukushima Dai-ichi nuclear accident, was also modeled and analyzed. A comparison of the Ecotracer results to sampled 137 Cs measurements in the coastal ocean area around Fukushima show the promise of the tool but also highlight some important limitations. Copyright © 2017 Elsevier Ltd. All rights reserved.
On the interpretation of domain averaged Fermi hole analyses of correlated wavefunctions.
Francisco, E; Martín Pendás, A; Costales, Aurora
2014-03-14
Few methods allow for a physically sound analysis of chemical bonds in cases where electron correlation may be a relevant factor. The domain averaged Fermi hole (DAFH) analysis, a tool firstly proposed by Robert Ponec in the 1990's to provide interpretations of the chemical bonding existing between two fragments Ω and Ω' that divide the real space exhaustively, is one of them. This method allows for a partition of the delocalization index or bond order between Ω and Ω' into one electron contributions, but the chemical interpretation of its parameters has been firmly established only for single determinant wavefunctions. In this paper we report a general interpretation based on the concept of excluded density that is also valid for correlated descriptions. Both analytical models and actual computations on a set of simple molecules (H2, N2, LiH, and CO) are discussed, and a classification of the possible DAFH situations is presented. Our results show that this kind of analysis may reveal several correlated assisted bonding patterns that might be difficult to detect using other methods. In agreement with previous knowledge, we find that the effective bond order in covalent links decreases due to localization of electrons driven by Coulomb correlation.
Potential Flow Theory and Operation Guide for the Panel Code PMARC. Version 14
NASA Technical Reports Server (NTRS)
Ashby, Dale L.
1999-01-01
The theoretical basis for PMARC, a low-order panel code for modeling complex three-dimensional bodies, in potential flow, is outlined. PMARC can be run on a wide variety of computer platforms, including desktop machines, workstations, and supercomputers. Execution times for PMARC vary tremendously depending on the computer resources used, but typically range from several minutes for simple or moderately complex cases to several hours for very large complex cases. Several of the advanced features currently included in the code, such as internal flow modeling, boundary layer analysis, and time-dependent flow analysis, including problems involving relative motion, are discussed in some detail. The code is written in Fortran77, using adjustable-size arrays so that it can be easily redimensioned to match problem requirements and computer hardware constraints. An overview of the program input is presented. A detailed description of the input parameters is provided in the appendices. PMARC results for several test cases are presented along with analytic or experimental data, where available. The input files for these test cases are given in the appendices. PMARC currently supports plotfile output formats for several commercially available graphics packages. The supported graphics packages are Plot3D, Tecplot, and PmarcViewer.
NASA Technical Reports Server (NTRS)
Loeser, H. R.
1986-01-01
The Botany Facility allows the growth of higher plants and fungi over a period of 6 months maximum. It is a payload planned for the second flight of the Eureca platform around 1990. Major tasks of the Life Support Subsystem (LSS) of the Botany Facility include the control of the pressure and composition of the atmosphere within the plant/fungi growth chambers, control of the temperature and humidity of the air and the regulation of the soil water content within specified limits. Previous studies have shown that various LSS concepts are feasible ranging from heavy, simple and cheap to light, complex and expensive solutions. A summary of those concepts is given. A new approach to accomplish control of the temperature and humidity of the air within the growth chambers based on water reclamation is discussed. This reclamation is achieved by condensation with a heat pump and capillary transport of the condensate back into the soil of the individual growth chamber. Some analytical estimates are given in order to obtain guidelines for circulation flow rates and to determine the specific power consumption.
Kinetic Energy Transfer Process in a Double Shell Leading to Robust Burn
NASA Astrophysics Data System (ADS)
Montgomery, D. S.; Daughton, W. S.; Albright, B. J.; Wilson, D. C.; Loomis, E. N.; Merritt, E. C.; Dodd, E. S.; Kirkpatrick, R. C.; Watt, R. G.; Rosen, M. D.
2017-10-01
A goal of double shell capsule implosions is to impart sufficient internal energy to the D-T fuel at stagnation in order to obtain robust α-heating and burn with low hot spot convergence, C.R. < 10. A simple description of the kinetic energy transfer from the outer shell to the inner shell is found using shock physics and adiabatic compression, and compares well with 1D modeling. An isobaric model for the stagnation phase of the inner shell is used to determine the ideal partition of internal energy in the D-T fuel. Robust burn of the fuel requires, at minimum, that α-heating exceeds the rate of cooling by expansion of the hot spot so that the yield occurs before the hot spot disassembles, which is then used to define a minimum requirement for robust burn. One potential advantage of a double shell capsule compared to single shell capsules is the use of a heavy metal pusher, which may lead to a longer hot spot disassembly time. We present these analytic results and compare them to 1D and 2D radiation-hydrodynamic simulations. Work performed under the auspices of DOE by LANL under contract DE-AC52-06NA25396.
Modelling ecological systems in a changing world
Evans, Matthew R.
2012-01-01
The world is changing at an unprecedented rate. In such a situation, we need to understand the nature of the change and to make predictions about the way in which it might affect systems of interest; often we may also wish to understand what might be done to mitigate the predicted effects. In ecology, we usually make such predictions (or forecasts) by making use of mathematical models that describe the system and projecting them into the future, under changed conditions. Approaches emphasizing the desirability of simple models with analytical tractability and those that use assumed causal relationships derived statistically from data currently dominate ecological modelling. Although such models are excellent at describing the way in which a system has behaved, they are poor at predicting its future state, especially in novel conditions. In order to address questions about the impact of environmental change, and to understand what, if any, action might be taken to ameliorate it, ecologists need to develop the ability to project models into novel, future conditions. This will require the development of models based on understanding the processes that result in a system behaving the way it does, rather than relying on a description of the system, as a whole, remaining valid indefinitely. PMID:22144381
Writing analytic element programs in Python.
Bakker, Mark; Kelson, Victor A
2009-01-01
The analytic element method is a mesh-free approach for modeling ground water flow at both the local and the regional scale. With the advent of the Python object-oriented programming language, it has become relatively easy to write analytic element programs. In this article, an introduction is given of the basic principles of the analytic element method and of the Python programming language. A simple, yet flexible, object-oriented design is presented for analytic element codes using multiple inheritance. New types of analytic elements may be added without the need for any changes in the existing part of the code. The presented code may be used to model flow to wells (with either a specified discharge or drawdown) and streams (with a specified head). The code may be extended by any hydrogeologist with a healthy appetite for writing computer code to solve more complicated ground water flow problems. Copyright © 2009 The Author(s). Journal Compilation © 2009 National Ground Water Association.
Let's Go Off the Grid: Subsurface Flow Modeling With Analytic Elements
NASA Astrophysics Data System (ADS)
Bakker, M.
2017-12-01
Subsurface flow modeling with analytic elements has the major advantage that no grid or time stepping are needed. Analytic element formulations exist for steady state and transient flow in layered aquifers and unsaturated flow in the vadose zone. Analytic element models are vector-based and consist of points, lines and curves that represent specific features in the subsurface. Recent advances allow for the simulation of partially penetrating wells and multi-aquifer wells, including skin effect and wellbore storage, horizontal wells of poly-line shape including skin effect, sharp changes in subsurface properties, and surface water features with leaky beds. Input files for analytic element models are simple, short and readable, and can easily be generated from, for example, GIS databases. Future plans include the incorporation of analytic element in parts of grid-based models where additional detail is needed. This presentation will give an overview of advanced flow features that can be modeled, many of which are implemented in free and open-source software.
NASA Technical Reports Server (NTRS)
Lautenschlager, L.; Perry, C. R., Jr. (Principal Investigator)
1981-01-01
The development of formulae for the reduction of multispectral scanner measurements to a single value (vegetation index) for predicting and assessing vegetative characteristics is addressed. The origin, motivation, and derivation of some four dozen vegetation indices are summarized. Empirical, graphical, and analytical techniques are used to investigate the relationships among the various indices. It is concluded that many vegetative indices are very similar, some being simple algebraic transforms of others.
A pipette-based calibration system for fast-scan cyclic voltammetry with fast response times.
Ramsson, Eric S
2016-01-01
Fast-scan cyclic voltammetry (FSCV) is an electrochemical technique that utilizes the oxidation and/or reduction of an analyte of interest to infer rapid changes in concentrations. In order to calibrate the resulting oxidative or reductive current, known concentrations of an analyte must be introduced under controlled settings. Here, I describe a simple and cost-effective method, using a Petri dish and pipettes, for the calibration of carbon fiber microelectrodes (CFMs) using FSCV.
Fabrication of plasmonic cavity arrays for SERS analysis
NASA Astrophysics Data System (ADS)
Li, Ning; Feng, Lei; Teng, Fei; Lu, Nan
2017-05-01
The plasmonic cavity arrays are ideal substrates for surface enhanced Raman scattering analysis because they can provide hot spots with large volume for analyte molecules. The large area increases the probability to make more analyte molecules on hot spots and leads to a high reproducibility. Therefore, to develop a simple method for creating cavity arrays is important. Herein, we demonstrate how to fabricate a V and W shape cavity arrays by a simple method based on self-assembly. Briefly, the V and W shape cavity arrays are respectively fabricated by taking KOH etching on a nanohole and a nanoring array patterned silicon (Si) slides. The nanohole array is generated by taking a reactive ion etching on a Si slide assembled with monolayer of polystyrene (PS) spheres. The nanoring array is generated by taking a reactive ion etching on a Si slide covered with a monolayer of octadecyltrichlorosilane before self-assembling PS spheres. Both plasmonic V and W cavity arrays can provide large hot area, which increases the probability for analyte molecules to deposit on the hot spots. Taking 4-Mercaptopyridine as analyte probe, the enhancement factor can reach 2.99 × 105 and 9.97 × 105 for plasmonic V cavity and W cavity array, respectively. The relative standard deviations of the plasmonic V and W cavity arrays are 6.5% and 10.2% respectively according to the spectra collected on 20 random spots.
Fabrication of plasmonic cavity arrays for SERS analysis.
Li, Ning; Feng, Lei; Teng, Fei; Lu, Nan
2017-05-05
The plasmonic cavity arrays are ideal substrates for surface enhanced Raman scattering analysis because they can provide hot spots with large volume for analyte molecules. The large area increases the probability to make more analyte molecules on hot spots and leads to a high reproducibility. Therefore, to develop a simple method for creating cavity arrays is important. Herein, we demonstrate how to fabricate a V and W shape cavity arrays by a simple method based on self-assembly. Briefly, the V and W shape cavity arrays are respectively fabricated by taking KOH etching on a nanohole and a nanoring array patterned silicon (Si) slides. The nanohole array is generated by taking a reactive ion etching on a Si slide assembled with monolayer of polystyrene (PS) spheres. The nanoring array is generated by taking a reactive ion etching on a Si slide covered with a monolayer of octadecyltrichlorosilane before self-assembling PS spheres. Both plasmonic V and W cavity arrays can provide large hot area, which increases the probability for analyte molecules to deposit on the hot spots. Taking 4-Mercaptopyridine as analyte probe, the enhancement factor can reach 2.99 × 10 5 and 9.97 × 10 5 for plasmonic V cavity and W cavity array, respectively. The relative standard deviations of the plasmonic V and W cavity arrays are 6.5% and 10.2% respectively according to the spectra collected on 20 random spots.
Dervisevic, Muamer; Senel, Mehmet; Sagir, Tugba; Isik, Sevim
2017-04-15
The detection of cancer cells through important molecular recognition target such as sialic acid is significant for the clinical diagnosis and treatment. There are many electrochemical cytosensors developed for cancer cells detection but most of them have complicated fabrication processes which results in poor reproducibility and reliability. In this study, a simple, low-cost, and highly sensitive electrochemical cytosensor was designed based on boronic acid-functionalized polythiophene. In cytosensors fabrication simple single-step procedure was used which includes coating pencil graphite electrode (PGE) by means of electro-polymerization of 3-Thienyl boronic acid and Thiophen. Electrochemical impedance spectroscopy and cyclic voltammetry were used as an analytical methods to optimize and measure analytical performances of PGE/P(TBA 0.5 Th 0.5 ) based electrode. Cytosensor showed extremely good analytical performances in detection of cancer cells with linear rage of 1×10 1 to 1×10 6 cellsmL -1 exhibiting low detection limit of 10 cellsmL -1 and incubation time of 10min. Next to excellent analytical performances, it showed high selectivity towards AGS cancer cells when compared to HEK 293 normal cells and bone marrow mesenchymal stem cells (BM-hMSCs). This method is promising for future applications in early stage cancer diagnosis. Copyright © 2016 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Pekşen, Ertan; Yas, Türker; Kıyak, Alper
2014-09-01
We examine the one-dimensional direct current method in anisotropic earth formation. We derive an analytic expression of a simple, two-layered anisotropic earth model. Further, we also consider a horizontally layered anisotropic earth response with respect to the digital filter method, which yields a quasi-analytic solution over anisotropic media. These analytic and quasi-analytic solutions are useful tests for numerical codes. A two-dimensional finite difference earth model in anisotropic media is presented in order to generate a synthetic data set for a simple one-dimensional earth. Further, we propose a particle swarm optimization method for estimating the model parameters of a layered anisotropic earth model such as horizontal and vertical resistivities, and thickness. The particle swarm optimization is a naturally inspired meta-heuristic algorithm. The proposed method finds model parameters quite successfully based on synthetic and field data. However, adding 5 % Gaussian noise to the synthetic data increases the ambiguity of the value of the model parameters. For this reason, the results should be controlled by a number of statistical tests. In this study, we use probability density function within 95 % confidence interval, parameter variation of each iteration and frequency distribution of the model parameters to reduce the ambiguity. The result is promising and the proposed method can be used for evaluating one-dimensional direct current data in anisotropic media.
Conservative Analytical Collision Probabilities for Orbital Formation Flying
NASA Technical Reports Server (NTRS)
Carpenter, J. Russell
2004-01-01
The literature offers a number of approximations for analytically and/or efficiently computing the probability of collision between two space objects. However, only one of these techniques is a completely analytical approximation that is suitable for use in the preliminary design phase, when it is more important to quickly analyze a large segment of the trade space than it is to precisely compute collision probabilities. Unfortunately, among the types of formations that one might consider, some combine a range of conditions for which this analytical method is less suitable. This work proposes a simple, conservative approximation that produces reasonable upper bounds on the collision probability in such conditions. Although its estimates are much too conservative under other conditions, such conditions are typically well suited for use of the existing method.
Pre-concentration technique for reduction in "Analytical instrument requirement and analysis"
NASA Astrophysics Data System (ADS)
Pal, Sangita; Singha, Mousumi; Meena, Sher Singh
2018-04-01
Availability of analytical instruments for a methodical detection of known and unknown effluents imposes a serious hindrance in qualification and quantification. Several analytical instruments such as Elemental analyzer, ICP-MS, ICP-AES, EDXRF, ion chromatography, Electro-analytical instruments which are not only expensive but also time consuming, required maintenance, damaged essential parts replacement which are of serious concern. Move over for field study and instant detection installation of these instruments are not convenient to each and every place. Therefore, technique such as pre-concentration of metal ions especially for lean stream elaborated and justified. Chelation/sequestration is the key of immobilization technique which is simple, user friendly, most effective, least expensive, time efficient; easy to carry (10g - 20g vial) to experimental field/site has been demonstrated.
Conservative Analytical Collision Probability for Design of Orbital Formations
NASA Technical Reports Server (NTRS)
Carpenter, J. Russell
2004-01-01
The literature offers a number of approximations for analytically and/or efficiently computing the probability of collision between two space objects. However, only one of these techniques is a completely analytical approximation that is suitable for use in the preliminary design phase, when it is more important to quickly analyze a large segment of the trade space than it is to precisely compute collision probabilities. Unfortunately, among the types of formations that one might consider, some combine a range of conditions for which this analytical method is less suitable. This work proposes a simple, conservative approximation that produces reasonable upper bounds on the collision probability in such conditions. Although its estimates are much too conservative under other conditions, such conditions are typically well suited for use of the existing method.
NASA Technical Reports Server (NTRS)
Sheverev, V. A.; Khromov, N. A.; Kojiro, D. R.; Fonda, Mark (Technical Monitor)
2002-01-01
Admixtures to helium of 100 ppm and 5 ppm of nitrogen, and 100 ppm and 10 ppm of carbon monoxide were identified and measured in the helium discharge afterglow using an electrical probe placed into the plasma. For nitrogen and carbon monoxide gases, the measured electron energy spectra display distinct characteristic peaks (fingerprints). Location of the peaks on the energy scale is determined by the ionization energies of the analyte molecules. Nitrogen and carbon monoxide fingerprints were also observed in a binary mixture of these gases in helium, and the relative concentration analytes has been predicted. The technically simple and durable method is considered a good candidate for a number of analytical applications, and in particular, in GC and for analytical flight instrumentation.
SIMPL Systems, or: Can We Design Cryptographic Hardware without Secret Key Information?
NASA Astrophysics Data System (ADS)
Rührmair, Ulrich
This paper discusses a new cryptographic primitive termed SIMPL system. Roughly speaking, a SIMPL system is a special type of Physical Unclonable Function (PUF) which possesses a binary description that allows its (slow) public simulation and prediction. Besides this public key like functionality, SIMPL systems have another advantage: No secret information is, or needs to be, contained in SIMPL systems in order to enable cryptographic protocols - neither in the form of a standard binary key, nor as secret information hidden in random, analog features, as it is the case for PUFs. The cryptographic security of SIMPLs instead rests on (i) a physical assumption on their unclonability, and (ii) a computational assumption regarding the complexity of simulating their output. This novel property makes SIMPL systems potentially immune against many known hardware and software attacks, including malware, side channel, invasive, or modeling attacks.
Improved Design of Tunnel Supports : Executive Summary
DOT National Transportation Integrated Search
1979-12-01
This report focuses on improvement of design methodologies related to the ground-structure interaction in tunneling. The design methods range from simple analytical and empirical methods to sophisticated finite element techniques as well as an evalua...
System safety engineering analysis handbook
NASA Technical Reports Server (NTRS)
Ijams, T. E.
1972-01-01
The basic requirements and guidelines for the preparation of System Safety Engineering Analysis are presented. The philosophy of System Safety and the various analytic methods available to the engineering profession are discussed. A text-book description of each of the methods is included.
The Exponential Expansion of Simulation in Research
2012-12-01
exponential growth of computing power. Although other analytic approaches also benefit from this trend, keyword searches of several scholarly search ... engines reveal that the reliance on simulation is increasing more rapidly. A descriptive analysis paints a compelling picture: simulation is frequently
DESCRIPTION OF ATMOSPHERIC TRANSPORT PROCESSES IN EULERIAN AIR QUALITY MODELS
Key differences among many types of air quality models are the way atmospheric advection and turbulent diffusion processes are treated. Gaussian models use analytical solutions of the advection-diffusion equations. Lagrangian models use a hypothetical air parcel concept effecti...
Adverse outcome pathway networks: Development, analytics, and applications
Product Description:The US EPA is developing more cost effective and efficient ways to evaluate chemical safety using high throughput and computationally based testing strategies. An important component of this approach is the ability to translate chemical effects on fundamental ...
Coupled Particle Transport and Pattern Formation in a Nonlinear Leaky-Box Model
NASA Technical Reports Server (NTRS)
Barghouty, A. F.; El-Nemr, K. W.; Baird, J. K.
2009-01-01
Effects of particle-particle coupling on particle characteristics in nonlinear leaky-box type descriptions of the acceleration and transport of energetic particles in space plasmas are examined in the framework of a simple two-particle model based on the Fokker-Planck equation in momentum space. In this model, the two particles are assumed coupled via a common nonlinear source term. In analogy with a prototypical mathematical system of diffusion-driven instability, this work demonstrates that steady-state patterns with strong dependence on the magnetic turbulence but a rather weak one on the coupled particles attributes can emerge in solutions of a nonlinearly coupled leaky-box model. The insight gained from this simple model may be of wider use and significance to nonlinearly coupled leaky-box type descriptions in general.
[In defence of the diagnosis of simple schizophrenia: reflections on a case presentation].
Martínez Serrano, José; Medina Garrido, María L; Consuegra Sánchez, Rosario; Del Cerro Oñate, Matias; López-Mesa, José L; González Matás, Juana
2012-01-01
Since the first case descriptions of dementia praecox (Diem, 1903), the diagnosis of simple schizophrenia has continued to be controversial. The questioning of its descriptive validity and its reliability, as well as its infrequent use, has led to it being eliminated as a sub-type of schizophrenia in the DSM-III. Criteria for the diagnosis of «simple deteriorative disorder» are currently included in the DSM-IV-TR as a disorder requiring more studies for its possible inclusion. An attempt is made, using a clinical case, to perform a historical review of the concept of simple schizophrenia, and at the same what has led to the reflection on the possible reasons for the controversy, and a potential route to resolve it. Using a controversial clinical case, which meets ICD-10 clinical criteria for simple schizophrenia (and those of the DSM-IV-TR for the simple deteriorative disorder), we reflect on the symptoms and diagnostic difficulties. A literature review and update on the subjects was also performed. Our patient highlights, by the absence in the clinical picture of the most obvious positive psychotic symptoms, the tendency by psychiatrists to identify the diagnosis of schizophrenia with the presence of the same, at least at some time during its evolution. The use of neuroimaging tests was useful to assess the level of deterioration and prognosis of the patient. Considering simple schizophrenia in the differential diagnosis of other chronic deteriorative disorders could increase its recognition in the initial phases. The use of neuropsychological function tests, and looking for typical deteriorative patterns of the schizophrenia spectrum, could help to increase the reliability of the diagnosis. Copyright © 2011 SEP y SEPB. Published by Elsevier Espana. All rights reserved.
An analytic performance model of disk arrays and its application
NASA Technical Reports Server (NTRS)
Lee, Edward K.; Katz, Randy H.
1991-01-01
As disk arrays become widely used, tools for understanding and analyzing their performance become increasingly important. In particular, performance models can be invaluable in both configuring and designing disk arrays. Accurate analytic performance models are desirable over other types of models because they can be quickly evaluated, are applicable under a wide range of system and workload parameters, and can be manipulated by a range of mathematical techniques. Unfortunately, analytical performance models of disk arrays are difficult to formulate due to the presence of queuing and fork-join synchronization; a disk array request is broken up into independent disk requests which must all complete to satisfy the original request. We develop, validate, and apply an analytic performance model for disk arrays. We derive simple equations for approximating their utilization, response time, and throughput. We then validate the analytic model via simulation and investigate the accuracy of each approximation used in deriving the analytical model. Finally, we apply the analytical model to derive an equation for the optimal unit of data striping in disk arrays.
NASA Astrophysics Data System (ADS)
Falugi, P.; Olaru, S.; Dumur, D.
2010-08-01
This article proposes an explicit robust predictive control solution based on linear matrix inequalities (LMIs). The considered predictive control strategy uses different local descriptions of the system dynamics and uncertainties and thus allows the handling of less conservative input constraints. The computed control law guarantees constraint satisfaction and asymptotic stability. The technique is effective for a class of nonlinear systems embedded into polytopic models. A detailed discussion of the procedures which adapt the partition of the state space is presented. For the practical implementation the construction of suitable (explicit) descriptions of the control law are described upon concrete algorithms.
A simple geometrical model describing shapes of soap films suspended on two rings
NASA Astrophysics Data System (ADS)
Herrmann, Felix J.; Kilvington, Charles D.; Wildenberg, Rebekah L.; Camacho, Franco E.; Walecki, Wojciech J.; Walecki, Peter S.; Walecki, Eve S.
2016-09-01
We measured and analysed the stability of two types of soap films suspended on two rings using the simple conical frusta-based model, where we use common definition of conical frustum as a portion of a cone that lies between two parallel planes cutting it. Using frusta-based we reproduced very well-known results for catenoid surfaces with and without a central disk. We present for the first time a simple conical frusta based spreadsheet model of the soap surface. This very simple, elementary, geometrical model produces results surprisingly well matching the experimental data and known exact analytical solutions. The experiment and the spreadsheet model can be used as a powerful teaching tool for pre-calculus and geometry students.
Orthodontics for the dog. Treatment methods.
Ross, D L
1986-09-01
This article considers the prevention of orthodontic problems, occlusal adjustments, simple tooth movements, rotational techniques, tipping problems, adjustment of crown height, descriptions of common orthodontic appliances, and problems associated with therapy.
Describing contrast across scales
NASA Astrophysics Data System (ADS)
Syed, Sohaib Ali; Iqbal, Muhammad Zafar; Riaz, Muhammad Mohsin
2017-06-01
Due to its sensitive nature against illumination and noise distributions, contrast is not widely used for image description. On the contrary, the human perception of contrast along different spatial frequency bandwidths provides a powerful discriminator function that can be modeled in a robust manner against local illumination. Based upon this observation, a dense local contrast descriptor is proposed and its potential in different applications of computer vision is discussed. Extensive experiments reveal that this simple yet effective description performs well in comparison with state of the art image descriptors. We also show the importance of this description in multiresolution pansharpening framework.
Simple Analytic Expressions for the Magnetic Field of a Circular Current Loop
NASA Technical Reports Server (NTRS)
Simpson, James C.; Lane, John E.; Immer, Christopher D.; Youngquist, Robert C.
2001-01-01
Analytic expressions for the magnetic induction (magnetic flux density, B) of a simple planar circular current loop have been published in Cartesian and cylindrical coordinates [1,2], and are also known implicitly in spherical coordinates [3]. In this paper, we present explicit analytic expressions for B and its spatial derivatives in Cartesian, cylindrical, and spherical coordinates for a filamentary current loop. These results were obtained with extensive use of Mathematica "TM" and are exact throughout all space outside of the conductor. The field expressions reduce to the well-known limiting cases and satisfy V · B = 0 and V x B = 0 outside the conductor. These results are general and applicable to any model using filamentary circular current loops. Solenoids of arbitrary size may be easily modeled by approximating the total magnetic induction as the sum of those for the individual loops. The inclusion of the spatial derivatives expands their utility to magnetohydrodynamics where the derivatives are required. The equations can be coded into any high-level programming language. It is necessary to numerically evaluate complete elliptic integrals of the first and second kind, but this capability is now available with most programming packages.