Sample records for simulation helps explain

  1. Adding Badging to a Marketing Simulation to Increase Motivation to Learn

    ERIC Educational Resources Information Center

    Saxton, M. Kim

    2015-01-01

    Badging has become a popular tool for obtaining social recognition for personal accomplishments. This innovation describes a way to add badging to a marketing simulation to increase student motivation to achieve the simulation's goals. Assessments indicate that badging both motivates students to perform better and helps explain students' perceived…

  2. Ultrasonic Phased Array Inspection Simulations of Welded Components at NASA

    NASA Technical Reports Server (NTRS)

    Roth, D. J.; Tokars, R. P.; Martin, R. E.; Rauser, R. W.; Aldrin, J. C.; Schumacher, E. J.

    2009-01-01

    Comprehensive and accurate inspections of welded components have become of increasing importance as NASA develops new hardware such as Ares rocket segments for future exploration missions. Simulation and modeling will play an increased role in the future for nondestructive evaluation in order to better understand the physics of the inspection process and help explain the experimental results. It will also help to prove or disprove the feasibility for an inspection method or inspection scenario, help optimize inspections, and allow to a first approximation limits of detectability. This study presents simulation and experimental results for an ultrasonic phased array inspection of a critical welded structure important for NASA future exploration vehicles.

  3. Statistical Literacy: Simulations with Dolphins

    ERIC Educational Resources Information Center

    Strayer, Jeremy; Matuszewski, Amber

    2016-01-01

    In this article, Strayer and Matuszewski present a six-phase strategy that teachers can use to help students develop a conceptual understanding of inferential hypothesis testing through simulation. As Strayer and Matuszewski discuss the strategy, they describe each phase in general, explain how they implemented the phase while teaching their…

  4. Modeling Education on the Real World.

    ERIC Educational Resources Information Center

    Hunter, Beverly

    1983-01-01

    Discusses educational applications of computer simulation and model building for grades K to 8, with emphasis on the usefulness of the computer simulation language, micro-DYNAMO, for programing and understanding the models which help to explain social and natural phenomena. A new textbook for junior-senior high school students is noted. (EAO)

  5. Ames Lab 101: osgBullet

    ScienceCinema

    McCorkle, Doug

    2017-12-27

    Ames Laboratory scientist Doug McCorkle explains osgBullet, a 3-D virtual simulation software, and how it helps engineers design complex products and systems in a realistic, real-time virtual environment.

  6. Ultrasonic Phased Array Inspection Experiments and Simulations for AN Isogrid Structural Element with Cracks

    NASA Astrophysics Data System (ADS)

    Roth, D. J.; Tokars, R. P.; Martin, R. E.; Rauser, R. W.; Aldrin, J. C.; Schumacher, E. J.

    2010-02-01

    In this investigation, a T-shaped aluminum alloy isogrid stiffener element used in aerospace applications was inspected with ultrasonic phased array methods. The isogrid stiffener element had various crack configurations emanating from bolt holes. Computational simulation methods were used to mimic the experiments in order to help understand experimental results. The results of this study indicate that it is at least partly feasible to interrogate this type of geometry with the given flaw configurations using phased array ultrasonics. The simulation methods were critical in helping explain the experimental results and, with some limitation, can be used to predict inspection results.

  7. A Computer Simulation to Help in Teaching Induction Phenomena

    ERIC Educational Resources Information Center

    Mihas, Pavlos

    2003-01-01

    The motion of a magnet through a coil is analysed through a model of magnetic monopoles. The magnetic flux of a monopole passing through a loop is explained and also its rate of change. By a superposition of voltages produced by the monopoles on the coils the shape of the voltage versus time graph is explained. Also examined is the interaction of…

  8. Ultrasonic Phased Array Inspection for an Isogrid Structural Element with Cracks

    NASA Technical Reports Server (NTRS)

    Roth, D. J.; Tokars, R. P.; Martin, R. E.; Rauser, R. W.; Aldrin, J. C.; Schumacher, E. J.

    2010-01-01

    In this investigation, a T-shaped aluminum alloy isogrid stiffener element used in aerospace applications was inspected with ultrasonic phased array methods. The isogrid stiffener element had various crack configurations emanating from bolt holes. Computational simulation methods were used to mimic the experiments in order to help understand experimental results. The results of this study indicate that it is at least partly feasible to interrogate this type of geometry with the given flaw configurations using phased array ultrasonics. The simulation methods were critical in helping explain the experimental results and, with some limitation, can be used to predict inspection results.

  9. Teaching Ionic Solvation Structure with a Monte Carlo Liquid Simulation Program

    NASA Astrophysics Data System (ADS)

    Serrano, Agostinho; Santos, Flávia M. T.; Greca, Ileana M.

    2004-09-01

    It is shown how basic aspects of ionic solvation structure, a fundamental topic for understanding different concepts and levels of representations of chemical structure and transformation, can be taught with the help of a Monte Carlo simulation package for molecular liquids. By performing a pair distribution function analysis of the solvation of Na + , Cl , and Ar in water, it is shown that it is feasible to explain the differences in solvation for these differently charged solutes. Visual representations of the solvated ions can also be employed to help the teaching activity. This may serve as an introduction to the study of solvation structure in chemistry undergraduate courses. The advantages of using tested, up-to-date scientific simulation programs as the fundamental bricks in the construction of virtual laboratories is also discussed.

  10. Start-to-end simulation of the shot-noise driven microbunching instability experiment at the Linac Coherent Light Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Qiang, J.; Ding, Y.; Emma, P.

    The shot-noise driven microbunching instability can significantly degrade electron beam quality in x-ray free electron laser light sources. Experiments were carried out at the Linac Coherent Light Source (LCLS) to study this instability. Here in this paper, we present start-to-end simulations of the shot-noise driven microbunching instability experiment at the LCLS using the real number of electrons. The simulation results reproduce the measurements quite well. A microbunching self-heating mechanism is also illustrated in the simulation, which helps explain the experimental observation.

  11. Start-to-end simulation of the shot-noise driven microbunching instability experiment at the Linac Coherent Light Source

    DOE PAGES

    Qiang, J.; Ding, Y.; Emma, P.; ...

    2017-05-23

    The shot-noise driven microbunching instability can significantly degrade electron beam quality in x-ray free electron laser light sources. Experiments were carried out at the Linac Coherent Light Source (LCLS) to study this instability. Here in this paper, we present start-to-end simulations of the shot-noise driven microbunching instability experiment at the LCLS using the real number of electrons. The simulation results reproduce the measurements quite well. A microbunching self-heating mechanism is also illustrated in the simulation, which helps explain the experimental observation.

  12. A Proposed Design for an Interim Space Rescue Ferry Vehicle.

    DTIC Science & Technology

    1985-12-01

    Mussack of the SOS Lab deserves credit for helping me to determine the effects of plume impingement on vehicle control. Jack Tiffany, head of the AFIT... Effective Thruster Forces .. .......... . 85 XV. Simulation Results--Solo MMU/Primary Control Mode ....... .................... 91 XVI. Simulation...will be made as explained in 2 and 3 (9:2-34--36). Figure 2.7 does not reflect the effects of a limb motion filter, which briefly delays AAH response

  13. A laminar cortical model of stereopsis and 3D surface perception: closure and da Vinci stereopsis.

    PubMed

    Cao, Yongqiang; Grossberg, Stephen

    2005-01-01

    A laminar cortical model of stereopsis and 3D surface perception is developed and simulated. The model describes how monocular and binocular oriented filtering interact with later stages of 3D boundary formation and surface filling-in in the LGN and cortical areas V1, V2, and V4. It proposes how interactions between layers 4, 3B, and 2/3 in V1 and V2 contribute to stereopsis, and how binocular and monocular information combine to form 3D boundary and surface representations. The model includes two main new developments: (1) It clarifies how surface-to-boundary feedback from V2 thin stripes to pale stripes helps to explain data about stereopsis. This feedback has previously been used to explain data about 3D figure-ground perception. (2) It proposes that the binocular false match problem is subsumed under the Gestalt grouping problem. In particular, the disparity filter, which helps to solve the correspondence problem by eliminating false matches, is realized using inhibitory interneurons as part of the perceptual grouping process by horizontal connections in layer 2/3 of cortical area V2. The enhanced model explains all the psychophysical data previously simulated by Grossberg and Howe (2003), such as contrast variations of dichoptic masking and the correspondence problem, the effect of interocular contrast differences on stereoacuity, Panum's limiting case, the Venetian blind illusion, stereopsis with polarity-reversed stereograms, and da Vinci stereopsis. It also explains psychophysical data about perceptual closure and variations of da Vinci stereopsis that previous models cannot yet explain.

  14. An interactive learning environment for health care professionals.

    PubMed Central

    Cobbs, E.; Pincetl, P.; Silverman, B.; Liao, R. L.; Motta, C.

    1994-01-01

    This article summarizes experiences to date with building and deploying a clinical simulator that medical students use as part of a 3rd year primary care rotation. The simulated microworld helps students and health care professionals gain experience with and learn meta-cognitive skills for the care of complex patient populations that require treatment in the biopsychosocial-value dimensions. We explain lessons learned and next steps resulting from use of the program by over 300 users to date. PMID:7949975

  15. Monte Carlo errors with less errors

    NASA Astrophysics Data System (ADS)

    Wolff, Ulli; Alpha Collaboration

    2004-01-01

    We explain in detail how to estimate mean values and assess statistical errors for arbitrary functions of elementary observables in Monte Carlo simulations. The method is to estimate and sum the relevant autocorrelation functions, which is argued to produce more certain error estimates than binning techniques and hence to help toward a better exploitation of expensive simulations. An effective integrated autocorrelation time is computed which is suitable to benchmark efficiencies of simulation algorithms with regard to specific observables of interest. A Matlab code is offered for download that implements the method. It can also combine independent runs (replica) allowing to judge their consistency.

  16. Dynamics of Unusual Debris Flows on Martian Sand Dunes

    NASA Technical Reports Server (NTRS)

    Miyamoto, Hideaki; Dohm, James M.; Baker, Victor R.; Beyer, Ross A.; Bourke, Mary

    2004-01-01

    Gullies that dissect sand dunes in Russell impact crater often display debris flow-like deposits in their distal reaches. The possible range of both the rheological properties and the flow rates are estimated using a numerical simulation code of a Bingham plastic flow to help explain the formation of these features. Our simulated results are best explained by a rapid debris flow. For example, a debris flow with the viscosity of 10(exp 2) Pa s and the yield strength of 10(exp 2) Pa can form the observed deposits with a flow rate of 0.5 cu m/s sustained over several minutes and total discharged water volume on the order of hundreds of cubic meters, which may be produced by melting a surface layer of interstitial ice within the dune deposits to several centimeters depth.

  17. Assessing influences on social vulnerability to wildfire using surveys, spatial data and wildfire simulations.

    PubMed

    Paveglio, Travis B; Edgeley, Catrin M; Stasiewicz, Amanda M

    2018-05-01

    A growing body of research focuses on identifying patterns among human populations most at risk from hazards such as wildfire and the factors that help explain performance of mitigations that can help reduce that risk. Emerging policy surrounding wildfire management emphasizes the need to better understand such social vulnerability-or human populations' potential exposure to and sensitivity from wildfire-related impacts, including their ability to reduce negative impacts from the hazard. Studies of social vulnerability to wildfire often pair secondary demographic data with a variety of vegetation and wildfire simulation models to map potential risk. However, many of the assumptions made by those researchers about the demographic, spatial or perceptual factors that influence social vulnerability to wildfire have not been fully evaluated or tested against objective measures of potential wildfire risk. The research presented here utilizes self-reported surveys, GIS data, and wildfire simulations to test the relationships between select perceptual, demographic, and property characteristics of property owners against empirically simulated metrics for potential wildfire related damages or exposure. We also evaluate how those characteristics relate to property owners' performance of mitigations or support for fire management. Our results suggest that parcel characteristics provide the most significant explanation of variability in wildfire exposure, sensitivity and overall wildfire risk, while the positive relationship between income or property values and components of social vulnerability stands in contrast to typical assumptions from existing literature. Respondents' views about agency or government management helped explain a significant amount of variance in wildfire sensitivity, while the importance of wildfire risk in selecting a residence was an important influence on mitigation action. We use these and other results from our effort to discuss updated considerations for determining social vulnerability to wildfire and articulate alternative means to collect such information. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. [Application of fluid mechanics and simulation: urinary tract and ureteral catheters.

    PubMed

    Gómez-Blanco, J C; Martínez-Reina, J; Cruz, D; Blas Pagador, J; Sánchez-Margallo, F M; Soria, F

    2016-10-01

    The mechanics of urine during its transport from the renal pelvis to the bladder is of great interest for urologists. The knowledge of the different physical variables and their interrelationship, both in physiologic movements and pathologies, will help a better diagnosis and treatment. The objective of this chapter is to show the physics principles and their most relevant basic relations in urine transport, and to bring them over the clinical world. For that, we explain the movement of urine during peristalsis, ureteral obstruction and in a ureter with a stent. This explanation is based in two tools used in bioengineering: the theoretical analysis through the Theory of concontinuous media and Ffluid mechanics and computational simulation that offers a practical solution for each scenario. Moreover, we review other contributions of bioengineering to the field of Urology, such as physical simulation or additive and subtractive manufacturing techniques. Finally, we list the current limitations for these tools and the technological development lines with more future projection. In this chapter we aim to help urologists to understand some important concepts of bioengineering, promoting multidisciplinary cooperation to offer complementary tools that help in diagnosis and treatment of diseases.

  19. Understanding the extraocular muscles and oculomotor, trochlear, and abducens nerves through a simulation in physical examination training: an innovative approach.

    PubMed

    Zhang, Niu; He, Xiaohua

    2010-01-01

    The purpose of this study was to investigate the effect of an innovative exhibitory eye model simulation in a physical examination laboratory format on explaining Listing's Law concerning the individual extraocular muscle action and the rationale for cranial nerve testing. Participants were 71 volunteers in the third quarter of a chiropractic training program. The study involved a specially designed eyeball model used to explain the movements of individual extraocular muscles based on Listing's law and their cranial innervations in conjunction with the physical examination. Pre- and post-written tests were used to assess participants' understanding of the subjects taught. The test results were compared with those of nonparticipants who also took the same pre- and posttests. An independent samples t-test of the posttest showed a significant difference between the groups. The study group students achieved higher scores than their counterparts in the control group. Using an innovative approach to explain Listing's law and rationale for cranial nerve tests can improve physical examination skill and help produce more effective written test results.

  20. Intentional strategies that make co-actors more predictable: the case of signaling.

    PubMed

    Pezzulo, Giovanni; Dindo, Haris

    2013-08-01

    Pickering & Garrod (P&G) explain dialogue dynamics in terms of forward modeling and prediction-by-simulation mechanisms. Their theory dissolves a strict segregation between production and comprehension processes, and it links dialogue to action-based theories of joint action. We propose that the theory can also incorporate intentional strategies that increase communicative success: for example, signaling strategies that help remaining predictable and forming common ground.

  1. Role of Updraft Velocity in Temporal Variability of Global Cloud Hydrometeor Number

    NASA Technical Reports Server (NTRS)

    Sullivan, Sylvia C.; Lee, Dong Min; Oreopoulos, Lazaros; Nenes, Athanasios

    2016-01-01

    Understanding how dynamical and aerosol inputs affect the temporal variability of hydrometeor formation in climate models will help to explain sources of model diversity in cloud forcing, to provide robust comparisons with data, and, ultimately, to reduce the uncertainty in estimates of the aerosol indirect effect. This variability attribution can be done at various spatial and temporal resolutions with metrics derived from online adjoint sensitivities of droplet and crystal number to relevant inputs. Such metrics are defined and calculated from simulations using the NASA Goddard Earth Observing System Model, Version 5 (GEOS-5) and the National Center for Atmospheric Research Community Atmosphere Model Version 5.1 (CAM5.1). Input updraft velocity fluctuations can explain as much as 48% of temporal variability in output ice crystal number and 61% in droplet number in GEOS-5 and up to 89% of temporal variability in output ice crystal number in CAM5.1. In both models, this vertical velocity attribution depends strongly on altitude. Despite its importance for hydrometeor formation, simulated vertical velocity distributions are rarely evaluated against observations due to the sparsity of relevant data. Coordinated effort by the atmospheric community to develop more consistent, observationally based updraft treatments will help to close this knowledge gap.

  2. When does power disparity help or hurt group performance?

    PubMed

    Tarakci, Murat; Greer, Lindred L; Groenen, Patrick J F

    2016-03-01

    Power differences are ubiquitous in social settings. However, the question of whether groups with higher or lower power disparity achieve better performance has thus far received conflicting answers. To address this issue, we identify 3 underlying assumptions in the literature that may have led to these divergent findings, including a myopic focus on static hierarchies, an assumption that those at the top of hierarchies are competent at group tasks, and an assumption that equality is not possible. We employ a multimethod set of studies to examine these assumptions and to understand when power disparity will help or harm group performance. First, our agent-based simulation analyses show that by unpacking these common implicit assumptions in power research, we can explain earlier disparate findings--power disparity benefits group performance when it is dynamically aligned with the power holder's task competence, and harms group performance when held constant and/or is not aligned with task competence. Second, our empirical findings in both a field study of fraud investigation groups and a multiround laboratory study corroborate the simulation results. We thereby contribute to research on power by highlighting a dynamic understanding of power in groups and explaining how current implicit assumptions may lead to opposing findings. (c) 2016 APA, all rights reserved).

  3. Role of updraft velocity in temporal variability of global cloud hydrometeor number

    DOE PAGES

    Sullivan, Sylvia C.; Lee, Dongmin; Oreopoulos, Lazaros; ...

    2016-05-16

    Understanding how dynamical and aerosol inputs affect the temporal variability of hydrometeor formation in climate models will help to explain sources of model diversity in cloud forcing, to provide robust comparisons with data, and, ultimately, to reduce the uncertainty in estimates of the aerosol indirect effect. This variability attribution can be done at various spatial and temporal resolutions with metrics derived from online adjoint sensitivities of droplet and crystal number to relevant inputs. Such metrics are defined and calculated from simulations using the NASA Goddard Earth Observing System Model, Version 5 (GEOS-5) and the National Center for Atmospheric Research Communitymore » Atmosphere Model Version 5.1 (CAM5.1). Input updraft velocity fluctuations can explain as much as 48% of temporal variability in output ice crystal number and 61% in droplet number in GEOS-5 and up to 89% of temporal variability in output ice crystal number in CAM5.1. In both models, this vertical velocity attribution depends strongly on altitude. Despite its importance for hydrometeor formation, simulated vertical velocity distributions are rarely evaluated against observations due to the sparsity of relevant data. Finally, coordinated effort by the atmospheric community to develop more consistent, observationally based updraft treatments will help to close this knowledge gap.« less

  4. Role of updraft velocity in temporal variability of global cloud hydrometeor number

    NASA Astrophysics Data System (ADS)

    Sullivan, Sylvia C.; Lee, Dongmin; Oreopoulos, Lazaros; Nenes, Athanasios

    2016-05-01

    Understanding how dynamical and aerosol inputs affect the temporal variability of hydrometeor formation in climate models will help to explain sources of model diversity in cloud forcing, to provide robust comparisons with data, and, ultimately, to reduce the uncertainty in estimates of the aerosol indirect effect. This variability attribution can be done at various spatial and temporal resolutions with metrics derived from online adjoint sensitivities of droplet and crystal number to relevant inputs. Such metrics are defined and calculated from simulations using the NASA Goddard Earth Observing System Model, Version 5 (GEOS-5) and the National Center for Atmospheric Research Community Atmosphere Model Version 5.1 (CAM5.1). Input updraft velocity fluctuations can explain as much as 48% of temporal variability in output ice crystal number and 61% in droplet number in GEOS-5 and up to 89% of temporal variability in output ice crystal number in CAM5.1. In both models, this vertical velocity attribution depends strongly on altitude. Despite its importance for hydrometeor formation, simulated vertical velocity distributions are rarely evaluated against observations due to the sparsity of relevant data. Coordinated effort by the atmospheric community to develop more consistent, observationally based updraft treatments will help to close this knowledge gap.

  5. Time domain simulation of novel photovoltaic materials

    NASA Astrophysics Data System (ADS)

    Chung, Haejun

    Thin-film silicon-based solar cells have operated far from the Shockley- Queisser limit in all experiments to date. Novel light-trapping structures, however, may help address this limitation. Finite-difference time domain simulation methods offer the potential to accurately determine the light-trapping potential of arbitrary dielectric structures, but suffer from materials modeling problems. In this thesis, existing dispersion models for novel photovoltaic materials will be reviewed, and a novel dispersion model, known as the quadratic complex rational function (QCRF), will be proposed. It has the advantage of accurately fitting experimental semiconductor dielectric values over a wide bandwidth in a numerically stable fashion. Applying the proposed dispersion model, a statistically correlated surface texturing method will be suggested, and light absorption rates of it will be explained. In future work, these designs will be combined with other structures and optimized to help guide future experiments.

  6. Who is that masked educator? Deconstructing the teaching and learning processes of an innovative humanistic simulation technique.

    PubMed

    McAllister, Margaret; Searl, Kerry Reid; Davis, Susan

    2013-12-01

    Simulation learning in nursing has long made use of mannequins, standardized actors and role play to allow students opportunity to practice technical body-care skills and interventions. Even though numerous strategies have been developed to mimic or amplify clinical situations, a common problem that is difficult to overcome in even the most well-executed simulation experiences, is that students may realize the setting is artificial and fail to fully engage, remember or apply the learning. Another problem is that students may learn technical competence but remain uncertain about communicating with the person. Since communication capabilities are imperative in human service work, simulation learning that only achieves technical competence in students is not fully effective for the needs of nursing education. Furthermore, while simulation learning is a burgeoning space for innovative practices, it has been criticized for the absence of a basis in theory. It is within this context that an innovative simulation learning experience named "Mask-Ed (KRS simulation)", has been deconstructed and the active learning components examined. Establishing a theoretical basis for creative teaching and learning practices provides an understanding of how, why and when simulation learning has been effective and it may help to distinguish aspects of the experience that could be improved. Three conceptual theoretical fields help explain the power of this simulation technique: Vygotskian sociocultural learning theory, applied theatre and embodiment. Copyright © 2013 Elsevier Ltd. All rights reserved.

  7. Monsoon Variability in the Arabian Sea from Global 0.08 deg HYCOM Simulations

    DTIC Science & Technology

    2015-09-30

    modes to help explain the series of events leading up to the anomalous behavior in the SC, the GW and upwelling strength . WORK COMPLETED...Number: N00014-15-1-2189 LONG-TERM GOALS The Arabian Sea upper ocean circulation switches direction seasonally due to the change in direction ...of the prevailing winds associated with the Indian Monsoon. Predictability of the monsoon circulation however is uncertain due to incomplete

  8. Linking Native and Invader Traits Explains Native Spider Population Responses to Plant Invasion.

    PubMed

    Smith, Jennifer N; Emlen, Douglas J; Pearson, Dean E

    2016-01-01

    Theoretically, the functional traits of native species should determine how natives respond to invader-driven changes. To explore this idea, we simulated a large-scale plant invasion using dead spotted knapweed (Centaurea stoebe) stems to determine if native spiders' web-building behaviors could explain differences in spider population responses to structural changes arising from C. stoebe invasion. After two years, irregular web-spiders were >30 times more abundant and orb weavers were >23 times more abundant on simulated invasion plots compared to controls. Additionally, irregular web-spiders on simulated invasion plots built webs that were 4.4 times larger and 5.0 times more likely to capture prey, leading to >2-fold increases in recruitment. Orb-weavers showed no differences in web size or prey captures between treatments. Web-spider responses to simulated invasion mimicked patterns following natural invasions, confirming that C. stoebe's architecture is likely the primary attribute driving native spider responses to these invasions. Differences in spider responses were attributable to differences in web construction behaviors relative to historic web substrate constraints. Orb-weavers in this system constructed webs between multiple plants, so they were limited by the overall quantity of native substrates but not by the architecture of individual native plant species. Irregular web-spiders built their webs within individual plants and were greatly constrained by the diminutive architecture of native plant substrates, so they were limited both by quantity and quality of native substrates. Evaluating native species traits in the context of invader-driven change can explain invasion outcomes and help to identify factors limiting native populations.

  9. Linking Native and Invader Traits Explains Native Spider Population Responses to Plant Invasion

    PubMed Central

    Emlen, Douglas J.; Pearson, Dean E.

    2016-01-01

    Theoretically, the functional traits of native species should determine how natives respond to invader-driven changes. To explore this idea, we simulated a large-scale plant invasion using dead spotted knapweed (Centaurea stoebe) stems to determine if native spiders’ web-building behaviors could explain differences in spider population responses to structural changes arising from C. stoebe invasion. After two years, irregular web-spiders were >30 times more abundant and orb weavers were >23 times more abundant on simulated invasion plots compared to controls. Additionally, irregular web-spiders on simulated invasion plots built webs that were 4.4 times larger and 5.0 times more likely to capture prey, leading to >2-fold increases in recruitment. Orb-weavers showed no differences in web size or prey captures between treatments. Web-spider responses to simulated invasion mimicked patterns following natural invasions, confirming that C. stoebe’s architecture is likely the primary attribute driving native spider responses to these invasions. Differences in spider responses were attributable to differences in web construction behaviors relative to historic web substrate constraints. Orb-weavers in this system constructed webs between multiple plants, so they were limited by the overall quantity of native substrates but not by the architecture of individual native plant species. Irregular web-spiders built their webs within individual plants and were greatly constrained by the diminutive architecture of native plant substrates, so they were limited both by quantity and quality of native substrates. Evaluating native species traits in the context of invader-driven change can explain invasion outcomes and help to identify factors limiting native populations. PMID:27082240

  10. Simulating Hadronic-to-Quark-Matter with Burn-UD: Recent work and astrophysical applications

    NASA Astrophysics Data System (ADS)

    Welbanks, Luis; Ouyed, Amir; Koning, Nico; Ouyed, Rachid

    2017-06-01

    We present the new developments in Burn-UD, our in-house hydrodynamic combustion code used to model the phase transition of hadronic-to-quark matter. Our two new modules add neutrino transport and the time evolution of a (u, d, s) quark star (QS). Preliminary simulations show that the inclusion of neutrino transport points towards new hydrodynamic instabilities that increase the burning speed. A higher burning speed could elicit the deflagration to detonation of a neutron star (NS) into a QS. We propose that a Quark-Nova (QN: the explosive transition of a NS to a QS) could help us explain the most energetic astronomical events to this day: superluminous supernovae (SLSNe). Our models consider a QN occurring in a massive binary, experiencing two common envelope stages and a QN occurring after the supernova explosion of a Wolf-Rayet (WO) star. Both models have been successful in explaining the double humped light curves of over half a dozen SLSNe. We also introduce SiRop our r-process simulation code and propose that a QN site has the hot temperatures and neutron densities required to make it an ideal site for the r-process.

  11. Kinetic simulations of gas breakdown in the dense plasma focus

    NASA Astrophysics Data System (ADS)

    Bennett, N.; Blasco, M.; Breeding, K.; DiPuccio, V.; Gall, B.; Garcia, M.; Gardner, S.; Gatling, J.; Hagen, E. C.; Luttman, A.; Meehan, B. T.; Molnar, S.; O'Brien, R.; Ormond, E.; Robbins, L.; Savage, M.; Sipe, N.; Welch, D. R.

    2017-06-01

    The first fully kinetic, collisional, and electromagnetic simulations of the breakdown phase of a MA-scale dense plasma focus are described and shown to agree with measured electrical characteristics, including breakdown time. In the model, avalanche ionization is driven by cathode electron emission, and this results in incomplete gas breakdown along the insulator. This reinforces the importance of the conditioning process that creates a metallic layer on the insulator surface. The simulations, nonetheless, help explain the relationship between the gas pressure, the insulator length, and the coaxial gap width. Previously, researchers noted three breakdown patterns related to pressure. Simulation and analytical results show that at low pressures, long ionization path lengths lead to volumetric breakdown, while high pressures lead to breakdown across the relatively small coaxial electrode gap. In an intermediate pressure regime, ionization path lengths are comparable to the insulator length which promotes ideal breakdown along the insulator surface.

  12. Assessing the dispersive and electrostatic components of the cohesive energy of ionic liquids using molecular dynamics simulations and molar refraction data.

    PubMed

    Shimizu, Karina; Tariq, Mohammad; Costa Gomes, Margarida F; Rebelo, Luís P N; Canongia Lopes, José N

    2010-05-06

    Molecular dynamics simulations were used to calculate the density and the cohesive molar internal energy of seventeen different ionic liquids in the liquid phase. The results were correlated with previously reported experimental density and molar refraction data. The link between the dispersive component of the total cohesive energy of the fluid and the corresponding molar refraction was established in an unequivocal way. The results have shown that the two components of the total cohesive energy (dispersive and electrostatic) exhibit strikingly different trends and ratios along different families of ionic liquids, a notion that may help explain their diverse behavior toward different molecular solutes and solvents.

  13. Tuning the critical solution temperature of polymers by copolymerization

    NASA Astrophysics Data System (ADS)

    Schulz, Bernhard; Chudoba, Richard; Heyda, Jan; Dzubiella, Joachim

    2015-12-01

    We study statistical copolymerization effects on the upper critical solution temperature (CST) of generic homopolymers by means of coarse-grained Langevin dynamics computer simulations and mean-field theory. Our systematic investigation reveals that the CST can change monotonically or non-monotonically with copolymerization, as observed in experimental studies, depending on the degree of non-additivity of the monomer (A-B) cross-interactions. The simulation findings are confirmed and qualitatively explained by a combination of a two-component Flory-de Gennes model for polymer collapse and a simple thermodynamic expansion approach. Our findings provide some rationale behind the effects of copolymerization and may be helpful for tuning CST behavior of polymers in soft material design.

  14. Metallicity gradient of the thick disc progenitor at high redshift

    NASA Astrophysics Data System (ADS)

    Kawata, Daisuke; Allende Prieto, Carlos; Brook, Chris B.; Casagrande, Luca; Ciucă, Ioana; Gibson, Brad K.; Grand, Robert J. J.; Hayden, Michael R.; Hunt, Jason A. S.

    2018-01-01

    We have developed a novel Markov Chain Monte Carlo chemical 'painting' technique to explore possible radial and vertical metallicity gradients for the thick disc progenitor. In our analysis, we match an N-body simulation to the data from the Apache Point Observatory Galactic Evolution Experiment survey. We assume that the thick disc has a constant scaleheight and has completed its formation at an early epoch, after which time radial mixing of its stars has taken place. Under these assumptions, we find that the initial radial metallicity gradient of the thick disc progenitor should not be negative, but either flat or even positive, to explain the current negative vertical metallicity gradient of the thick disc. Our study suggests that the thick disc was built-up in an inside-out and upside-down fashion, and older, smaller and thicker populations are more metal poor. In this case, star-forming discs at different epochs of the thick disc formation are allowed to have different radial metallicity gradients, including a negative one, which helps to explain a variety of slopes observed in high-redshift disc galaxies. This scenario helps to explain the positive slope of the metallicity-rotation velocity relation observed for the Galactic thick disc. On the other hand, radial mixing flattens the slope of an existing gradient.

  15. ISS Double-Gimbaled CMG Subsystem Simulation Using the Agile Development Method

    NASA Technical Reports Server (NTRS)

    Inampudi, Ravi

    2016-01-01

    This paper presents an evolutionary approach in simulating a cluster of 4 Control Moment Gyros (CMG) on the International Space Station (ISS) using a common sense approach (the agile development method) for concurrent mathematical modeling and simulation of the CMG subsystem. This simulation is part of Training systems for the 21st Century simulator which will provide training for crew members, instructors, and flight controllers. The basic idea of how the CMGs on the space station are used for its non-propulsive attitude control is briefly explained to set up the context for simulating a CMG subsystem. Next different reference frames and the detailed equations of motion (EOM) for multiple double-gimbal variable-speed control moment gyroscopes (DGVs) are presented. Fixing some of the terms in the EOM becomes the special case EOM for ISS's double-gimbaled fixed speed CMGs. CMG simulation development using the agile development method is presented in which customer's requirements and solutions evolve through iterative analysis, design, coding, unit testing and acceptance testing. At the end of the iteration a set of features implemented in that iteration are demonstrated to the flight controllers thus creating a short feedback loop and helping in creating adaptive development cycles. The unified modeling language (UML) tool is used in illustrating the user stories, class designs and sequence diagrams. This incremental development approach of mathematical modeling and simulating the CMG subsystem involved the development team and the customer early on, thus improving the quality of the working CMG system in each iteration and helping the team to accurately predict the cost, schedule and delivery of the software.

  16. A Statistical-Physics Approach to Language Acquisition and Language Change

    NASA Astrophysics Data System (ADS)

    Cassandro, Marzio; Collet, Pierre; Galves, Antonio; Galves, Charlotte

    1999-02-01

    The aim of this paper is to explain why Statistical Physics can help understanding two related linguistic questions. The first question is how to model first language acquisition by a child. The second question is how language change proceeds in time. Our approach is based on a Gibbsian model for the interface between syntax and prosody. We also present a simulated annealing model of language acquisition, which extends the Triggering Learning Algorithm recently introduced in the linguistic literature.

  17. The dark side of transparency: How and when pay administration practices affect employee helping.

    PubMed

    Bamberger, Peter; Belogolovsky, Elena

    2017-04-01

    This study examines a long-standing contention of practitioners and scholars alike, namely that pay transparency may adversely affect employees' tendency to offer assistance to coworkers. Drawing from research on social comparison, information vividness, and envy, we develop and test a moderated-mediation model positing that transparency adversely affects the amount of help individuals afford to peers who, based on pay for performance, are paid more than them. Testing our hypotheses in the context of a multiround simulation-based laboratory experiment, we find that this adverse effect of pay transparency on helping is largely explained by transparency's positive association with episodic envy, but only when individual differences grounded in differential social value orientations, specifically those regarding individualism beliefs and prosocial motivation, are taken into consideration. Implications for theory and practice are discussed. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  18. Matched Comparison Group Design Standards in Systematic Reviews of Early Childhood Interventions.

    PubMed

    Thomas, Jaime; Avellar, Sarah A; Deke, John; Gleason, Philip

    2017-06-01

    Systematic reviews assess the quality of research on program effectiveness to help decision makers faced with many intervention options. Study quality standards specify criteria that studies must meet, including accounting for baseline differences between intervention and comparison groups. We explore two issues related to systematic review standards: covariate choice and choice of estimation method. To help systematic reviews develop/refine quality standards and support researchers in using nonexperimental designs to estimate program effects, we address two questions: (1) How well do variables that systematic reviews typically require studies to account for explain variation in key child and family outcomes? (2) What methods should studies use to account for preexisting differences between intervention and comparison groups? We examined correlations between baseline characteristics and key outcomes using Early Childhood Longitudinal Study-Birth Cohort data to address Question 1. For Question 2, we used simulations to compare two methods-matching and regression adjustment-to account for preexisting differences between intervention and comparison groups. A broad range of potential baseline variables explained relatively little of the variation in child and family outcomes. This suggests the potential for bias even after accounting for these variables, highlighting the need for systematic reviews to provide appropriate cautions about interpreting the results of moderately rated, nonexperimental studies. Our simulations showed that regression adjustment can yield unbiased estimates if all relevant covariates are used, even when the model is misspecified, and preexisting differences between the intervention and the comparison groups exist.

  19. Evaluating the Characteristics of Social Vulnerability to Wildfire: Demographics, Perceptions, and Parcel Characteristics.

    PubMed

    Paveglio, Travis B; Prato, Tony; Edgeley, Catrin; Nalle, Darek

    2016-09-01

    A large body of research focuses on identifying patterns of human populations most at risk from hazards and the factors that help explain performance of mitigations that can help reduce that risk. One common concept in such studies is social vulnerability-human populations' potential exposure to, sensitivity from and ability to reduce negative impacts from a hazard. While there is growing interest in social vulnerability for wildfire, few studies have critically evaluated the characteristics that scholars often indicate influence social vulnerability to that hazard. This research utilizes surveys, wildfire simulations, and GIS data to test the relationships between select demographic, perceptual and parcel characteristics of property owners against empirically simulated metrics for wildfire exposure or wildfire-related damages and their performance of mitigation actions. Our results from Flathead County, MT, USA, suggest that parcel characteristics such as property value, building value, and the year structures were built explaining a significant amount of the variance in elements of social vulnerability. Demographic characteristics commonly used in social vulnerability analysis did not have significant relationships with measures of wildfire exposure or vulnerability. Part-time or full-time residency, age, perceived property risk, and year of development were among the few significant determinants of residents' performance of fuel reduction mitigations, although the significance of these factors varied across the levels of fuel reduction performed by homeowners. We use these and other results to argue for a renewed focus on the finer-scale characteristics that expose some populations to wildfire risk more than others.

  20. Evaluating the Characteristics of Social Vulnerability to Wildfire: Demographics, Perceptions, and Parcel Characteristics

    NASA Astrophysics Data System (ADS)

    Paveglio, Travis B.; Prato, Tony; Edgeley, Catrin; Nalle, Darek

    2016-09-01

    A large body of research focuses on identifying patterns of human populations most at risk from hazards and the factors that help explain performance of mitigations that can help reduce that risk. One common concept in such studies is social vulnerability—human populations' potential exposure to, sensitivity from and ability to reduce negative impacts from a hazard. While there is growing interest in social vulnerability for wildfire, few studies have critically evaluated the characteristics that scholars often indicate influence social vulnerability to that hazard. This research utilizes surveys, wildfire simulations, and GIS data to test the relationships between select demographic, perceptual and parcel characteristics of property owners against empirically simulated metrics for wildfire exposure or wildfire-related damages and their performance of mitigation actions. Our results from Flathead County, MT, USA, suggest that parcel characteristics such as property value, building value, and the year structures were built explaining a significant amount of the variance in elements of social vulnerability. Demographic characteristics commonly used in social vulnerability analysis did not have significant relationships with measures of wildfire exposure or vulnerability. Part-time or full-time residency, age, perceived property risk, and year of development were among the few significant determinants of residents' performance of fuel reduction mitigations, although the significance of these factors varied across the levels of fuel reduction performed by homeowners. We use these and other results to argue for a renewed focus on the finer-scale characteristics that expose some populations to wildfire risk more than others.

  1. Modeling Chagas Disease at Population Level to Explain Venezuela's Real Data

    PubMed Central

    González-Parra, Gilberto; Chen-Charpentier, Benito M.; Bermúdez, Moises

    2015-01-01

    Objectives In this paper we present an age-structured epidemiological model for Chagas disease. This model includes the interactions between human and vector populations that transmit Chagas disease. Methods The human population is divided into age groups since the proportion of infected individuals in this population changes with age as shown by real prevalence data. Moreover, the age-structured model allows more accurate information regarding the prevalence, which can help to design more specific control programs. We apply this proposed model to data from the country of Venezuela for two periods, 1961–1971, and 1961–1991 taking into account real demographic data for these periods. Results Numerical computer simulations are presented to show the suitability of the age-structured model to explain the real data regarding prevalence of Chagas disease in each of the age groups. In addition, a numerical simulation varying the death rate of the vector is done to illustrate prevention and control strategies against Chagas disease. Conclusion The proposed model can be used to determine the effect of control strategies in different age groups. PMID:26929912

  2. Lesson "Balance in Nature

    NASA Astrophysics Data System (ADS)

    Chapanova, V.

    2012-04-01

    Lesson "Balance in Nature" This simulation game-lesson (Balance in Nature) gives an opportunity for the students to show creativity, work independently, and to create models and ideas. It creates future-oriented thought connected to their experience, allowing them to propose solutions for global problems and personal responsibility for their activities. The class is divided in two teams. Each team chooses questions. 1. Question: Pollution in the environment. 2. Question: Care for nature and climate. The teams work on the chosen tasks. They make drafts, notes and formulate their solutions on small pieces of paper, explaining the impact on nature and society. They express their points of view using many different opinions. This generates alternative thoughts and results in creative solutions. With the new knowledge and positive behaviour defined, everybody realizes that they can do something positive towards nature and climate problems and the importance of individuals for solving global problems is evident. Our main goal is to recover the ecological balance, and everybody explains his or her own well-grounded opinions. In this work process the students obtain knowledge, skills and more responsible behaviour. This process, based on his or her own experience, dialogue and teamwork, helps the participant's self-development. Making the model "human↔ nature" expresses how human activities impact the natural Earth and how these impacts in turn affect society. Taking personal responsibility, we can reduce global warming and help the Earth. By helping nature we help ourselves. Teacher: Veselina Boycheva-Chapanova " Saint Patriarch Evtimii" Scholl Str. "Ivan Vazov"-19 Plovdiv Bulgaria

  3. Promotion of cooperation induced by appropriate payoff aspirations in a small-world networked game

    NASA Astrophysics Data System (ADS)

    Chen, Xiaojie; Wang, Long

    2008-01-01

    Based on learning theory, we adopt a stochastic learning updating rule to investigate the evolution of cooperation in the Prisoner’s Dilemma game on Newman-Watts small-world networks with different payoff aspiration levels. Interestingly, simulation results show that the mechanism of intermediate aspiration promoting cooperation resembles a resonancelike behavior, and there exists a ping-pong vibration of cooperation for large payoff aspiration. To explain the nontrivial dependence of the cooperation level on the aspiration level, we investigate the fractions of links, provide analytical results of the cooperation level, and find that the simulation results are in close agreement with analytical ones. Our work may be helpful in understanding the cooperative behavior induced by the aspiration level in society.

  4. Simulation of Cooling Rate Effects on Ti-48Al-2Cr-2Nb Crack Formation in Direct Laser Deposition

    NASA Astrophysics Data System (ADS)

    Yan, Lei; Li, Wei; Chen, Xueyang; Zhang, Yunlu; Newkirk, Joe; Liou, Frank; Dietrich, David

    2017-03-01

    Transient temperature history is vital in direct laser deposition (DLD) as it reveals the cooling rate at specific temperatures. Cooling rate directly relates to phase transformation and types of microstructure formed in deposits. In this paper, finite element analysis simulation was employed to study the transient temperature history and cooling rate at different experimental setups in the Ti-48Al-2Cr-2Nb DLD process. An innovative prediction strategy was developed to model with a moving Gaussian distribution heat source and element birth and death technology in ANSYS®, and fabricate crack-free deposits. This approach helps to understand and analyze the impact of cooling rate and also explain phase information gathered from x-ray diffraction.

  5. Indirect and Direct Signatures of Young Planets in Protoplanetary Disks

    NASA Astrophysics Data System (ADS)

    Zhu, Zhaohuan; Stone, James M.; Dong, Ruobing; Rafikov, Roman; Bai, Xue-Ning

    2015-12-01

    Directly finding young planets around protostars is challenging since protostars are highly variable and obscured by dust. However, young planets will interact with protoplanetary disks, inducing disk features such as gaps, spiral arms, and asymmetric features, which are much easier to be detected. Transitional disks, which are protoplanetary disks with gaps and holes, are excellent candidates for finding young planets. Although these disks have been studied extensively in observations (e.g. using Subaru, VLT, ALMA, EVLA), theoretical models still need to be developed to explain observations. We have constructed numerical simulations, including dust particle dynamics and MHD effects, to study planet-disk interaction, with an emphasis on explaining observations. Our simulations have successfully reproduced spiral arms, gaps and asymmetric features observed in transitional disks. Furthermore, by comparing with observations, we have constrained protoplanetary disk properties and pinpoint potential planets in these disks. We will present progress in constructing global simulations to study transitional disks, including using our recently developed Athena++ code with static-mesh-refinement for MHD. Finally we suggest that accreting circumplanetary disks can release an observable amount of energy and could be the key to detect young planets directly. We will discuss how JWST and next generation telescopes can help to find these young planets with circumplanetary disks.

  6. Patients whom neurologists find difficult to help

    PubMed Central

    Carson, A; Stone, J; Warlow, C; Sharpe, M

    2004-01-01

    Objective: To test the hypothesis that patients whose symptoms were less explained by organic disease would be perceived as more difficult to help. Methods: In a consecutive series of 300 new neurology outpatients, neurologists indicated on four point Likert-type scales how "difficult to help" they found the patient and to what extent the patient's symptoms were explained by organic disease. The patients' demographics, health status, number of somatic symptoms, and mental state were also assessed. Results: The neurologists rated 143 patients (48%) as "not at all difficult" to help, 111 (37%) as "somewhat difficult", 27 (9%) as "very difficult", and 18 (6%) as "extremely difficult". A logistic regression model was constructed and the hypothesis that patients whose symptoms were less explained by organic disease would be perceived as more difficult to help was supported. The only other measured variable that contributed to perceived difficulty was physical disability, but it explained only a small amount of the variance. Conclusions: Neurologists find patients whose symptoms are not explained by organic disease more difficult to help than their other patients. PMID:15548505

  7. Adaptive constructive processes and the future of memory.

    PubMed

    Schacter, Daniel L

    2012-11-01

    Memory serves critical functions in everyday life but is also prone to error. This article examines adaptive constructive processes, which play a functional role in memory and cognition but can also produce distortions, errors, and illusions. The article describes several types of memory errors that are produced by adaptive constructive processes and focuses in particular on the process of imagining or simulating events that might occur in one's personal future. Simulating future events relies on many of the same cognitive and neural processes as remembering past events, which may help to explain why imagination and memory can be easily confused. The article considers both pitfalls and adaptive aspects of future event simulation in the context of research on planning, prediction, problem solving, mind-wandering, prospective and retrospective memory, coping and positivity bias, and the interconnected set of brain regions known as the default network. PsycINFO Database Record (c) 2012 APA, all rights reserved.

  8. Simulation of ozone production in a complex circulation region using nested grids

    NASA Astrophysics Data System (ADS)

    Taghavi, M.; Cautenet, S.; Foret, G.

    2003-07-01

    During ESCOMPTE precampaign (15 June to 10 July 2000), three days of intensive pollution (IOP0) have been observed and simulated. The comprehensive RAMS model, version 4.3, coupled online with a chemical module including 29 species, has been used to follow the chemistry of the zone polluted over southern France. This online method can be used because the code is paralleled and the SGI 3800 computer is very powerful. Two runs have been performed: run1 with one grid and run2 with two nested grids. The redistribution of simulated chemical species (ozone, carbon monoxide, sulphur dioxide and nitrogen oxides) was compared to aircraft measurements and surface stations. The 2-grid run has given substantially better results than the one-grid run only because the former takes the outer pollutants into account. This online method helps to explain dynamics and to retrieve the chemical species redistribution with a good agreement.

  9. Simulation of ozone production in a complex circulation region using nested grids

    NASA Astrophysics Data System (ADS)

    Taghavi, M.; Cautenet, S.; Foret, G.

    2004-06-01

    During the ESCOMPTE precampaign (summer 2000, over Southern France), a 3-day period of intensive observation (IOP0), associated with ozone peaks, has been simulated. The comprehensive RAMS model, version 4.3, coupled on-line with a chemical module including 29 species, is used to follow the chemistry of the polluted zone. This efficient but time consuming method can be used because the code is installed on a parallel computer, the SGI 3800. Two runs are performed: run 1 with a single grid and run 2 with two nested grids. The simulated fields of ozone, carbon monoxide, nitrogen oxides and sulfur dioxide are compared with aircraft and surface station measurements. The 2-grid run looks substantially better than the run with one grid because the former takes the outer pollutants into account. This on-line method helps to satisfactorily retrieve the chemical species redistribution and to explain the impact of dynamics on this redistribution.

  10. The Atlas of Physiology and Pathophysiology: Web-based multimedia enabled interactive simulations.

    PubMed

    Kofranek, Jiri; Matousek, Stanislav; Rusz, Jan; Stodulka, Petr; Privitzer, Pavol; Matejak, Marek; Tribula, Martin

    2011-11-01

    The paper is a presentation of the current state of development for the Atlas of Physiology and Pathophysiology (Atlas). Our main aim is to provide a novel interactive multimedia application that can be used for biomedical education where (a) simulations are combined with tutorials and (b) the presentation layer is simplified while the underlying complexity of the model is retained. The development of the Atlas required the cooperation of many professionals including teachers, system analysts, artists, and programmers. During the design of the Atlas, tools were developed that allow for component-based creation of simulation models, creation of interactive multimedia and their final coordination into a compact unit based on the given design. The Atlas is a freely available online application, which can help to explain the function of individual physiological systems and the causes and symptoms of their disorders. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  11. Musculoskeletal simulation can help explain selective muscle degeneration in Duchenne muscular dystrophy.

    PubMed

    Hu, Xiao; Blemker, Silvia S

    2015-08-01

    Duchenne muscular dystrophy (DMD) is a genetic disease that occurs due to the deficiency of the dystrophin protein. Although dystrophin is deficient in all muscles, it is unclear why degeneration progresses differently across muscles in DMD. We hypothesized that each muscle undergoes a different degree of eccentric contraction during gait, which could contribute to the selective degeneration in lower limb muscle, as indicated by various amounts of fatty infiltration. By comparing eccentric contractions quantified from a previous multibody dynamic musculoskeletal gait simulation and fat fractions quantified in a recent imaging study, our preliminary analyses show a strong correlation between eccentric contractions during gait and lower limb muscle fat fractions, supporting our hypothesis. This knowledge is critical for developing safe exercise regimens for the DMD population. This study also provides supportive evidence for using multiscale modeling and simulation of the musculoskeletal system in future DMD research. © 2015 Wiley Periodicals, Inc.

  12. Breaking the Supermassive Black Hole Speed Limit

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smidt, Joseph

    A new computer simulation helps explain the existence of puzzling supermassive black holes observed in the early universe. The simulation is based on a computer code used to understand the coupling of radiation and certain materials. “Supermassive black holes have a speed limit that governs how fast and how large they can grow,” said Joseph Smidt of the Theoretical Design Division at Los Alamos National Laboratory. “The relatively recent discovery of supermassive black holes in the early development of the universe raised a fundamental question, how did they get so big so fast?” Using computer codes developed at Los Alamosmore » for modeling the interaction of matter and radiation related to the Lab’s stockpile stewardship mission, Smidt and colleagues created a simulation of collapsing stars that resulted in supermassive black holes forming in less time than expected, cosmologically speaking, in the first billion years of the universe.« less

  13. Simulation of fundamental atomization mechanisms in fuel sprays

    NASA Technical Reports Server (NTRS)

    Childs, Robert, E.; Mansour, Nagi N.

    1988-01-01

    Growth of instabilities on the liquid/gas interface in the initial region of fuel sprays is studied by means of numerical simulations. The simulations are based on solutions of the variable-density incompressible Navier-Stokes equations, which are obtained with a new numerical algorithm. The simulations give good agreement with analytical results for the instabilities on a liquid cylinder induced by surface tension and wind-induced instabilities. The effects of boundary layers on the wind-induced instabilities are investigated. It is found that a boundary layer reduces the growth rate for a single interface, and a comparison with inviscid theory suggests that boundary layer effects may be significantly more important than surface tension effects. The results yield a better estimate than inviscid theory for the drop sizes as reported for diesel sprays. Results for the planar jet show that boundary layer effects hasten the growth of Squire's 'symmetric' mode, which is responsible for jet disintegration. This result helps explain the rapid atomization which occurs in swirl and air-blast atomizers.

  14. Vertical Structure of Radiation-pressure-dominated Thin Disks: Link between Vertical Advection and Convective Stability

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gong, Hong-Yu; Gu, Wei-Min, E-mail: guwm@xmu.edu.cn

    2017-04-20

    In the classic picture of standard thin accretion disks, viscous heating is balanced by radiative cooling through the diffusion process, and the radiation-pressure-dominated inner disk suffers convective instability. However, recent simulations have shown that, owing to the magnetic buoyancy, the vertical advection process can significantly contribute to energy transport. In addition, in comparing the simulation results with the local convective stability criterion, no convective instability has been found. In this work, following on from simulations, we revisit the vertical structure of radiation-pressure-dominated thin disks and include the vertical advection process. Our study indicates a link between the additional energy transportmore » and the convectively stable property. Thus, the vertical advection not only significantly contributes to the energy transport, but it also plays an important role in making the disk convectively stable. Our analyses may help to explain the discrepancy between classic theory and simulations on standard thin disks.« less

  15. Watching the Solvation of Atoms in Liquids One Solvent Molecule at a Time

    NASA Astrophysics Data System (ADS)

    Bragg, Arthur E.; Glover, William J.; Schwartz, Benjamin J.

    2010-06-01

    We use mixed quantum-classical molecular dynamics simulations and ultrafast transient hole-burning spectroscopy to build a molecular-level picture of the motions of solvent molecules around Na atoms in liquid tetrahydrofuran. We find that even at room temperature, the solvation of Na atoms occurs in discrete steps, with the number of solvent molecules nearest the atom changing one at a time. This explains why the rate of solvent relaxation differs for different initial nonequilibrium states, and reveals how the solvent helps determine the identity of atomic species in liquids.

  16. On the Contribution of Large-Scale Structure to Strong Gravitational Lensing

    NASA Astrophysics Data System (ADS)

    Faure, C.; Kneib, J.-P.; Hilbert, S.; Massey, R.; Covone, G.; Finoguenov, A.; Leauthaud, A.; Taylor, J. E.; Pires, S.; Scoville, N.; Koekemoer, Anton M.

    2009-04-01

    We study the correlation between the locations of galaxy-galaxy strong-lensing candidates and tracers of large-scale structure from both weak lensing (WL) or X-ray emission. The Cosmological Evolution Survey (COSMOS) is a unique data set, combining deep, high resolution and contiguous imaging in which strong lenses have been discovered, plus unparalleled multiwavelength coverage. To help interpret the COSMOS data, we have also produced mock COSMOS strong- and WL observations, based on ray-tracing through the Millennium Simulation. In agreement with the simulations, we find that strongly lensed images with the largest angular separations are found in the densest regions of the COSMOS field. This is explained by a prevalence among the lens population in dense environments of elliptical galaxies with high total-to-stellar mass ratios, which can deflect light through larger angles. However, we also find that the overall fraction of elliptical galaxies with strong gravitational lensing is independent of the local mass density; this observation is not true of the simulations, which predict an increasing fraction of strong lenses in dense environments. The discrepancy may be a real effect, but could also be explained by various limitations of our analysis. For example, our visual search of strong lens systems could be incomplete and suffer from selection bias; the luminosity function of elliptical galaxies may differ between our real and simulated data; or the simplifying assumptions and approximations used in our lensing simulations may be inadequate. Work is therefore ongoing. Automated searches for strong lens systems will be particularly important in better constraining the selection function.

  17. May common model biases reduce CMIP5's ability to simulate the recent Pacific La Niña-like cooling?

    NASA Astrophysics Data System (ADS)

    Luo, Jing-Jia; Wang, Gang; Dommenget, Dietmar

    2018-02-01

    Over the recent three decades sea surface temperate (SST) in the eastern equatorial Pacific has decreased, which helps reduce the rate of global warming. However, most CMIP5 model simulations with historical radiative forcing do not reproduce this Pacific La Niña-like cooling. Based on the assumption of "perfect" models, previous studies have suggested that errors in simulated internal climate variations and/or external radiative forcing may cause the discrepancy between the multi-model simulations and the observation. But the exact causes remain unclear. Recent studies have suggested that observed SST warming in the other two ocean basins in past decades and the thermostat mechanism in the Pacific in response to increased radiative forcing may also play an important role in driving this La Niña-like cooling. Here, we investigate an alternative hypothesis that common biases of current state-of-the-art climate models may deteriorate the models' ability and can also contribute to this multi-model simulations-observation discrepancy. Our results suggest that underestimated inter-basin warming contrast across the three tropical oceans, overestimated surface net heat flux and underestimated local SST-cloud negative feedback in the equatorial Pacific may favor an El Niño-like warming bias in the models. Effects of the three common model biases do not cancel one another and jointly explain 50% of the total variance of the discrepancies between the observation and individual models' ensemble mean simulations of the Pacific SST trend. Further efforts on reducing common model biases could help improve simulations of the externally forced climate trends and the multi-decadal climate fluctuations.

  18. Developing approaches for linear mixed modeling in landscape genetics through landscape-directed dispersal simulations

    USGS Publications Warehouse

    Row, Jeffrey R.; Knick, Steven T.; Oyler-McCance, Sara J.; Lougheed, Stephen C.; Fedy, Bradley C.

    2017-01-01

    Dispersal can impact population dynamics and geographic variation, and thus, genetic approaches that can establish which landscape factors influence population connectivity have ecological and evolutionary importance. Mixed models that account for the error structure of pairwise datasets are increasingly used to compare models relating genetic differentiation to pairwise measures of landscape resistance. A model selection framework based on information criteria metrics or explained variance may help disentangle the ecological and landscape factors influencing genetic structure, yet there are currently no consensus for the best protocols. Here, we develop landscape-directed simulations and test a series of replicates that emulate independent empirical datasets of two species with different life history characteristics (greater sage-grouse; eastern foxsnake). We determined that in our simulated scenarios, AIC and BIC were the best model selection indices and that marginal R2 values were biased toward more complex models. The model coefficients for landscape variables generally reflected the underlying dispersal model with confidence intervals that did not overlap with zero across the entire model set. When we controlled for geographic distance, variables not in the underlying dispersal models (i.e., nontrue) typically overlapped zero. Our study helps establish methods for using linear mixed models to identify the features underlying patterns of dispersal across a variety of landscapes.

  19. Cell light scattering characteristic numerical simulation research based on FDTD algorithm

    NASA Astrophysics Data System (ADS)

    Lin, Xiaogang; Wan, Nan; Zhu, Hao; Weng, Lingdong

    2017-01-01

    In this study, finite-difference time-domain (FDTD) algorithm has been used to work out the cell light scattering problem. Before beginning to do the simulation contrast, finding out the changes or the differences between normal cells and abnormal cells which may be cancerous or maldevelopment is necessary. The preparation of simulation are building up the simple cell model of cell which consists of organelles, nucleus and cytoplasm and setting up the suitable precision of mesh. Meanwhile, setting up the total field scattering field source as the excitation source and far field projection analysis group is also important. Every step need to be explained by the principles of mathematic such as the numerical dispersion, perfect matched layer boundary condition and near-far field extrapolation. The consequences of simulation indicated that the position of nucleus changed will increase the back scattering intensity and the significant difference on the peak value of scattering intensity may result from the changes of the size of cytoplasm. The study may help us find out the regulations based on the simulation consequences and the regulations can be meaningful for early diagnosis of cancers.

  20. Realization of a Complex Control & Diagnosis System on Simplified Hardware

    NASA Astrophysics Data System (ADS)

    Stetter, R.; Swamy Prasad, M.

    2015-11-01

    Energy is an important factor in today's industrial environment. Pump systems account for about 20% of the total industrial electrical energy consumption. Several studies show that with proper monitoring, control and maintenance, the efficiency of pump systems can be increased. Controlling pump systems with intelligent systems can help to reduce a pump's energy consumption by up to one third of its original consumption. The research in this paper was carried out in the scope of a research project which involves modelling and simulation of pump systems. This paper focuses on the future implementation of modelling capabilities in PLCs (programmable logic controllers). The whole project aims to use a pump itself as the sensor rather than introducing external sensors into the system, which would increase the cost considerably. One promising approach for an economic and robust industrial implementation of this intelligence is the use of PLCs. PLCs can be simulated in multiple ways; in this project, Codesys was chosen for several reasons which are explained in this paper. The first part of this paper explains the modelling of a pump itself, the process load of the asynchronous motor with a control system, and the simulation possibilities of the motor in Codesys. The second part describes the simulation and testing of a system realized. The third part elaborates the Codesys system structure and interfacing of the system with external files. The final part consists of comparing the result with an earlier Matlab/SIMULINK model and original test data.

  1. Evolutionary robotics simulations help explain why reciprocity is rare in nature

    PubMed Central

    André, Jean-Baptiste; Nolfi, Stefano

    2016-01-01

    The relative rarity of reciprocity in nature, contrary to theoretical predictions that it should be widespread, is currently one of the major puzzles in social evolution theory. Here we use evolutionary robotics to solve this puzzle. We show that models based on game theory are misleading because they neglect the mechanics of behavior. In a series of experiments with simulated robots controlled by artificial neural networks, we find that reciprocity does not evolve, and show that this results from a general constraint that likely also prevents it from evolving in the wild. Reciprocity can evolve if it requires very few mutations, as is usually assumed in evolutionary game theoretic models, but not if, more realistically, it requires the accumulation of many adaptive mutations. PMID:27616139

  2. Chapter 24: Two- and Three-Dimensional Electronic Modeling of Thin-Film Solar Cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kanevce, Ana; Metzger, Wyatt K

    2016-07-22

    Modeling can provide physical insight to device operation, help distinguish important material properties from unimportant properties, predict trends, and help interpret experimental data. Numerical modeling is also useful to simulate different electro-optical experiments, in the presence of grain boundaries (GBs) and nonplanar junctions and geometries, and to help interpret data obtained in such experiments. This chapter presents methods for effective multidimensional modeling. The first step in creating a computational model is defining and providing discretization of a 2D area or a 3D volume. Two main approaches to the discretization have been used for studying solar cells: equivalent-circuit modeling and solvingmore » semiconductor equations. The chapter gives some examples of problems that were addressed with 2D or 3D modeling and the knowledge that was gained through them. Multidimensional modeling including GBs and other material variations is necessary to explain the device physics and experimental results present in diverse thin-film technologies.« less

  3. Visualization of the Invisible, Explanation of the Unknown, Ruggedization of the Unstable: Sensitivity Analysis, Virtual Tryout and Robust Design through Systematic Stochastic Simulation

    NASA Astrophysics Data System (ADS)

    Zwickl, Titus; Carleer, Bart; Kubli, Waldemar

    2005-08-01

    In the past decade, sheet metal forming simulation became a well established tool to predict the formability of parts. In the automotive industry, this has enabled significant reduction in the cost and time for vehicle design and development, and has helped to improve the quality and performance of vehicle parts. However, production stoppages for troubleshooting and unplanned die maintenance, as well as production quality fluctuations continue to plague manufacturing cost and time. The focus therefore has shifted in recent times beyond mere feasibility to robustness of the product and process being engineered. Ensuring robustness is the next big challenge for the virtual tryout / simulation technology. We introduce new methods, based on systematic stochastic simulations, to visualize the behavior of the part during the whole forming process — in simulation as well as in production. Sensitivity analysis explains the response of the part to changes in influencing parameters. Virtual tryout allows quick exploration of changed designs and conditions. Robust design and manufacturing guarantees quality and process capability for the production process. While conventional simulations helped to reduce development time and cost by ensuring feasible processes, robustness engineering tools have the potential for far greater cost and time savings. Through examples we illustrate how expected and unexpected behavior of deep drawing parts may be tracked down, identified and assigned to the influential parameters. With this knowledge, defects can be eliminated or springback can be compensated e.g.; the response of the part to uncontrollable noise can be predicted and minimized. The newly introduced methods enable more reliable and predictable stamping processes in general.

  4. On the recent warming in the subcloud layer entropy and vertically integrated moist static energy over South Asian Monsoon region.

    NASA Astrophysics Data System (ADS)

    Konduru, R.; Gupta, A.; Matsumoto, J.; Takahashi, H. G.

    2017-12-01

    In order to explain monsoon circulation, surface temperature gradients described as most traditional concept. However, it cannot explain certain important aspects of monsoon circulation. Later, convective quasi-equilibrium framework and vertically integrated atmospheric energy budget has become recognized theories to explain the monsoon circulation. In this article, same theories were analyzed and observed for the duration 1979-2010 over south Asian summer monsoon region. With the help of NCEP-R2, NOAA 20th Century, and Era-Interim reanalysis an important feature was noticed pertained to subcloud layer entropy and vertical moist static energy. In the last 32 years, subcloud layer entropy and vertically integrated moist static energy has shown significant seasonal warming all over the region with peak over the poleward flank of the cross-equatorial cell. The important reason related to the warming was found to be increase in surface enthalpy fluxes. Instead, other dynamical contributions pertained to the warming was also observed. Increase in positive anomalies of vertical advection of moist static energy over northern Bay of Bengal, Central India, Peninsular India, Eastern Arabian Sea, and Equatorial Indian Ocean was found to be an important dynamic factor contributing for warming of vertically integrated moist static energy. Along with it vertical moist stability has also supported the argument. Similar interpretations were perceived in the AMIP simulation of CCSM4 model. Further modeling experiments on this warming will be helpful to know the exact mechanism behind it.

  5. Analysis of Adhesive Characteristics of Asphalt Based on Atomic Force Microscopy and Molecular Dynamics Simulation.

    PubMed

    Xu, Meng; Yi, Junyan; Feng, Decheng; Huang, Yudong; Wang, Dongsheng

    2016-05-18

    Asphalt binder is a very important building material in infrastructure construction; it is commonly mixed with mineral aggregate and used to produce asphalt concrete. Owing to the large differences in physical and chemical properties between asphalt and aggregate, adhesive bonds play an important role in determining the performance of asphalt concrete. Although many types of adhesive bonding mechanisms have been proposed to explain the interaction forces between asphalt binder and mineral aggregate, few have been confirmed and characterized. In comparison with chemical interactions, physical adsorption has been considered to play a more important role in adhesive bonding between asphalt and mineral aggregate. In this study, the silicon tip of an atomic force microscope was used to represent silicate minerals in aggregate, and a nanoscale analysis of the characteristics of adhesive bonding between asphalt binder and the silicon tip was conducted via an atomic force microscopy (AFM) test and molecular dynamics (MD) simulations. The results of the measurements and simulations could help in better understanding of the bonding and debonding procedures in asphalt-aggregate mixtures during hot mixing and under traffic loading. MD simulations on a single molecule of a component of asphalt and monocrystalline silicon demonstrate that molecules with a higher atomic density and planar structure, such as three types of asphaltene molecules, can provide greater adhesive strength. However, regarding the real components of asphalt binder, both the MD simulations and AFM test indicate that the colloidal structural behavior of asphalt also has a large influence on the adhesion behavior between asphalt and silicon. A schematic model of the interaction between asphalt and silicon is presented, which can explain the effect of aging on the adhesion behavior of asphalt.

  6. What variables affect public perceptions for EMS meeting general community needs?

    PubMed

    Blau, Gary; Hochner, Arthur; Portwood, James

    2012-01-01

    In the fall, 2010, a phone survey of 928 respondents examined two research questions: does the general public perceive Emergency Medical Services (EMS) as meeting their community needs? And what factors or correlates help to explain EMS meeting community needs? To maximize geographical representation across the contiguous United States, a clustered stratified sampling strategy was used based upon zip codes across the 48 states. Results showed strong support by the sample for perceiving that EMS was meeting their general community needs. 17 percent of the variance in EMS meeting community needs was collectively explained by the demographic and perceptual variables in the regression model. Of the correlates tested, the strongest relationship was found between greater admiration for EMS professionals and higher perception of EMS meeting community needs. Study limitations included sampling households with only landline (no cell) phones, using a simulated emergency situation, and not collecting gender data.

  7. Strong control of Southern Ocean cloud reflectivity by ice-nucleating particles

    NASA Astrophysics Data System (ADS)

    Vergara-Temprado, Jesús; Miltenberger, Annette K.; Furtado, Kalli; Grosvenor, Daniel P.; Shipway, Ben J.; Hill, Adrian A.; Wilkinson, Jonathan M.; Field, Paul R.; Murray, Benjamin J.; Carslaw, Ken S.

    2018-03-01

    Large biases in climate model simulations of cloud radiative properties over the Southern Ocean cause large errors in modeled sea surface temperatures, atmospheric circulation, and climate sensitivity. Here, we combine cloud-resolving model simulations with estimates of the concentration of ice-nucleating particles in this region to show that our simulated Southern Ocean clouds reflect far more radiation than predicted by global models, in agreement with satellite observations. Specifically, we show that the clouds that are most sensitive to the concentration of ice-nucleating particles are low-level mixed-phase clouds in the cold sectors of extratropical cyclones, which have previously been identified as a main contributor to the Southern Ocean radiation bias. The very low ice-nucleating particle concentrations that prevail over the Southern Ocean strongly suppress cloud droplet freezing, reduce precipitation, and enhance cloud reflectivity. The results help explain why a strong radiation bias occurs mainly in this remote region away from major sources of ice-nucleating particles. The results present a substantial challenge to climate models to be able to simulate realistic ice-nucleating particle concentrations and their effects under specific meteorological conditions.

  8. Strong control of Southern Ocean cloud reflectivity by ice-nucleating particles

    PubMed Central

    Miltenberger, Annette K.; Furtado, Kalli; Grosvenor, Daniel P.; Shipway, Ben J.; Hill, Adrian A.; Wilkinson, Jonathan M.; Field, Paul R.

    2018-01-01

    Large biases in climate model simulations of cloud radiative properties over the Southern Ocean cause large errors in modeled sea surface temperatures, atmospheric circulation, and climate sensitivity. Here, we combine cloud-resolving model simulations with estimates of the concentration of ice-nucleating particles in this region to show that our simulated Southern Ocean clouds reflect far more radiation than predicted by global models, in agreement with satellite observations. Specifically, we show that the clouds that are most sensitive to the concentration of ice-nucleating particles are low-level mixed-phase clouds in the cold sectors of extratropical cyclones, which have previously been identified as a main contributor to the Southern Ocean radiation bias. The very low ice-nucleating particle concentrations that prevail over the Southern Ocean strongly suppress cloud droplet freezing, reduce precipitation, and enhance cloud reflectivity. The results help explain why a strong radiation bias occurs mainly in this remote region away from major sources of ice-nucleating particles. The results present a substantial challenge to climate models to be able to simulate realistic ice-nucleating particle concentrations and their effects under specific meteorological conditions. PMID:29490918

  9. Characterization of Bitumen Micro-Mechanical Behaviors Using AFM, Phase Dynamics Theory and MD Simulation.

    PubMed

    Hou, Yue; Wang, Linbing; Wang, Dawei; Guo, Meng; Liu, Pengfei; Yu, Jianxin

    2017-02-21

    Fundamental understanding of micro-mechanical behaviors in bitumen, including phase separation, micro-friction, micro-abrasion, etc., can help the pavement engineers better understand the bitumen mechanical performances at macroscale. Recent researches show that the microstructure evolution in bitumen will directly affect its surface structure and micro-mechanical performance. In this study, the bitumen microstructure and micro-mechanical behaviors are studied using Atomic Force Microscopy (AFM) experiments, Phase Dynamics Theory and Molecular Dynamics (MD) Simulation. The AFM experiment results show that different phase-structure will occur at the surface of the bitumen samples under certain thermodynamic conditions at microscale. The phenomenon can be explained using the phase dynamics theory, where the effects of stability parameter and temperature on bitumen microstructure and micro-mechanical behavior are studied combined with MD Simulation. Simulation results show that the saturates phase, in contrast to the naphthene aromatics phase, plays a major role in bitumen micro-mechanical behavior. A high stress zone occurs at the interface between the saturates phase and the naphthene aromatics phase, which may form discontinuities that further affect the bitumen frictional performance.

  10. Characterization of Bitumen Micro-Mechanical Behaviors Using AFM, Phase Dynamics Theory and MD Simulation

    PubMed Central

    Hou, Yue; Wang, Linbing; Wang, Dawei; Guo, Meng; Liu, Pengfei; Yu, Jianxin

    2017-01-01

    Fundamental understanding of micro-mechanical behaviors in bitumen, including phase separation, micro-friction, micro-abrasion, etc., can help the pavement engineers better understand the bitumen mechanical performances at macroscale. Recent researches show that the microstructure evolution in bitumen will directly affect its surface structure and micro-mechanical performance. In this study, the bitumen microstructure and micro-mechanical behaviors are studied using Atomic Force Microscopy (AFM) experiments, Phase Dynamics Theory and Molecular Dynamics (MD) Simulation. The AFM experiment results show that different phase-structure will occur at the surface of the bitumen samples under certain thermodynamic conditions at microscale. The phenomenon can be explained using the phase dynamics theory, where the effects of stability parameter and temperature on bitumen microstructure and micro-mechanical behavior are studied combined with MD Simulation. Simulation results show that the saturates phase, in contrast to the naphthene aromatics phase, plays a major role in bitumen micro-mechanical behavior. A high stress zone occurs at the interface between the saturates phase and the naphthene aromatics phase, which may form discontinuities that further affect the bitumen frictional performance. PMID:28772570

  11. Susceptibility to enhanced chemical migration from depression-focused preferential flow, High Plains aquifer

    USGS Publications Warehouse

    Gurdak, Jason J.; Walvoord, Michelle Ann; McMahon, Peter B.

    2008-01-01

    Aquifer susceptibility to contamination is controlled in part by the inherent hydrogeologic properties of the vadose zone, which includes preferential-flow pathways. The purpose of this study was to investigate the importance of seasonal ponding near leaky irrigation wells as a mechanism for depression-focused preferential flow and enhanced chemical migration through the vadose zone of the High Plains aquifer. Such a mechanism may help explain the widespread presence of agrichemicals in recently recharged groundwater despite estimates of advective chemical transit times through the vadose zone from diffuse recharge that exceed the historical period of agriculture. Using a combination of field observations, vadose zone flow and transport simulations, and probabilistic neural network modeling, we demonstrated that vadose zone transit times near irrigation wells range from 7 to 50 yr, which are one to two orders of magnitude faster than previous estimates based on diffuse recharge. These findings support the concept of fast and slow transport zones and help to explain the previous discordant findings of long vadose zone transit times and the presence of agrichemicals at the water table. Using predictions of aquifer susceptibility from probabilistic neural network models, we delineated approximately 20% of the areal extent of the aquifer to have conditions that may promote advective chemical transit times to the water table of <50 yr if seasonal ponding and depression-focused flow exist. This aquifer-susceptibility map may help managers prioritize areas for groundwater monitoring or implementation of best management practices.

  12. Aggregated N-of-1 randomized controlled trials: modern data analytics applied to a clinically valid method of intervention effectiveness.

    PubMed

    Cushing, Christopher C; Walters, Ryan W; Hoffman, Lesa

    2014-03-01

    Aggregated N-of-1 randomized controlled trials (RCTs) combined with multilevel modeling represent a methodological advancement that may help bridge science and practice in pediatric psychology. The purpose of this article is to offer a primer for pediatric psychologists interested in conducting aggregated N-of-1 RCTs. An overview of N-of-1 RCT methodology is provided and 2 simulated data sets are analyzed to demonstrate the clinical and research potential of the methodology. The simulated data example demonstrates the utility of aggregated N-of-1 RCTs for understanding the clinical impact of an intervention for a given individual and the modeling of covariates to explain why an intervention worked for one patient and not another. Aggregated N-of-1 RCTs hold potential for improving the science and practice of pediatric psychology.

  13. Influence of Ionization and Beam Quality on Interaction of TW-Peak CO2 Laser with Hydrogen Plasma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Samulyak, Roman

    3D numerical simulations of the interaction of a powerful CO2 laser with hydrogen jets demonstrating the role of ionization and laser beam quality are presented. Simulations are performed in support of the plasma wakefield accelerator experiments being conducted at the BNL Accelerator Test Facility (ATF). The CO2 laser at BNL ATF has several potential advantages for laser wakefield acceleration compared to widely used solid-state lasers. SPACE, a parallel relativistic Particle-in-Cell code, developed at SBU and BNL, has been used in these studies. A novelty of the code is its set of efficient atomic physics algorithms that compute ionization and recombinationmore » rates on the grid and transfer them to particles. The primary goal of the initial BNL experiments was to characterize the plasma density by measuring the sidebands in the spectrum of the probe laser. Simulations, that resolve hydrogen ionization and laser spectra, help explain several trends that were observed in the experiments.« less

  14. Rediscovery of the doldrums in storm-resolving simulations over the tropical Atlantic

    NASA Astrophysics Data System (ADS)

    Klocke, Daniel; Brueck, Matthias; Hohenegger, Cathy; Stevens, Bjorn

    2017-12-01

    The doldrums — a zone of calm and variable winds in the deep tropics between the trades — were of key importance to nineteenth century maritime travel. As a result, the region was a focus in atmospheric science at that time. However, as sailing ships were replaced by steamboats, scientific interest shifted to the heavy precipitating storms within the doldrums: the deep convective systems of the intertropical convergence zone. Now, in storm-system-resolving simulations over a period of two months that cover a large part of the tropical Atlantic, the doldrums are one of the most prominent features. The doldrums are substantially less pronounced in coarser-resolution simulations that use a parameterization for convection, despite their large-scale extent. We conclude that explicitly representing the storm scale dynamics and their coupling to the surface wind on the storm-system scales helps to maintain the systems of winds that define the doldrums. We suggest that the lack of these wind systems could explain the persistent tropical precipitation biases in climate models.

  15. Kinetic simulations of gas breakdown in the dense plasma focus

    DOE PAGES

    Bennett, N.; Blasco, M.; Breeding, K.; ...

    2017-06-09

    We describe the first fully-kinetic, collisional, and electromagnetic simulations of the breakdown phase of a MA-scale dense plasma focus and are shown to agree with measured electrical characteristics, including breakdown time. In the model, avalanche ionization is driven by cathode electron emission and this results in incomplete gas breakdown along the insulator. This reinforces the importance of the conditioning process that creates a metallic layer on the insulator surface. The simulations, nonetheless, help explain the relationship between the gas pressure, the insulator length, and the coaxial gap width. In the past, researchers noted three breakdown patterns related to pressure. Simulationmore » and analytic results show that at low pressures, long ionization path lengths lead to volumetric breakdown, while high pressures lead to breakdown across the relatively small coaxial electrode gap. In an intermediate pressure regime, ionization path lengths are comparable to the insulator length which promotes ideal breakdown along the insulator surface.« less

  16. Circadian Misalignment Increases C-Reactive Protein and Blood Pressure in Chronic Shift Workers.

    PubMed

    Morris, Christopher J; Purvis, Taylor E; Mistretta, Joseph; Hu, Kun; Scheer, Frank A J L

    2017-04-01

    Shift work is a risk factor for inflammation, hypertension, and cardiovascular disease. This increased risk cannot be fully explained by classical risk factors. Shift workers' behavioral and environmental cycles are typically misaligned relative to their endogenous circadian system. However, there is little information on the impact of acute circadian misalignment on cardiovascular disease risk in shift workers, independent of differences in work stress, food quality, and other factors that are likely to differ between night and day shifts. Thus, our objectives were to determine the independent effect of circadian misalignment on 24-h high-sensitivity C-reactive protein (hs-CRP; a marker of systemic inflammation) and blood pressure levels-cardiovascular disease risk factors-in chronic shift workers. Chronic shift workers undertook two 3-day laboratory protocols that simulated night work, comprising 12-hour inverted behavioral and environmental cycles (circadian misalignment) or simulated day work (circadian alignment), using a randomized, crossover design. Circadian misalignment increased 24-h hs-CRP by 11% ( p < 0.0001). Circadian misalignment increased 24-h systolic blood pressure (SBP) and diastolic blood pressure (DBP) by 1.4 mmHg and 0.8 mmHg, respectively (both p ≤ 0.038). The misalignment-mediated increase in 24-h SBP was primarily explained by an increase in SBP during the wake period (+1.7 mmHg; p = 0.017), whereas the misalignment-mediated increase in 24-h DBP was primarily explained by an increase in DBP during the sleep opportunity (+1.8 mmHg; p = 0.005). Circadian misalignment per se increases hs-CRP and blood pressure in shift workers. This may help explain the increased inflammation, hypertension, and cardiovascular disease risk in shift workers.

  17. Using Computer Simulations for Promoting Model-based Reasoning. Epistemological and Educational Dimensions

    NASA Astrophysics Data System (ADS)

    Develaki, Maria

    2017-11-01

    Scientific reasoning is particularly pertinent to science education since it is closely related to the content and methodologies of science and contributes to scientific literacy. Much of the research in science education investigates the appropriate framework and teaching methods and tools needed to promote students' ability to reason and evaluate in a scientific way. This paper aims (a) to contribute to an extended understanding of the nature and pedagogical importance of model-based reasoning and (b) to exemplify how using computer simulations can support students' model-based reasoning. We provide first a background for both scientific reasoning and computer simulations, based on the relevant philosophical views and the related educational discussion. This background suggests that the model-based framework provides an epistemologically valid and pedagogically appropriate basis for teaching scientific reasoning and for helping students develop sounder reasoning and decision-taking abilities and explains how using computer simulations can foster these abilities. We then provide some examples illustrating the use of computer simulations to support model-based reasoning and evaluation activities in the classroom. The examples reflect the procedure and criteria for evaluating models in science and demonstrate the educational advantages of their application in classroom reasoning activities.

  18. Impact of the Indian part of the summer MJO on West Africa using nudged climate simulations

    NASA Astrophysics Data System (ADS)

    Mohino, Elsa; Janicot, Serge; Douville, Hervé; Li, Laurent Z. X.

    2012-06-01

    Observational evidence suggests a link between the summer Madden Julian Oscillation (MJO) and anomalous convection over West Africa. This link is further studied with the help of the LMDZ atmospheric general circulation model. The approach is based on nudging the model towards the reanalysis in the Asian monsoon region. The simulation successfully captures the convection associated with the summer MJO in the nudging region. Outside this region the model is free to evolve. Over West Africa it simulates convection anomalies that are similar in magnitude, structure, and timing to the observed ones. In accordance with the observations, the simulation shows that 15-20 days after the maximum increase (decrease) of convection in the Indian Ocean there is a significant reduction (increase) in West African convection. The simulation strongly suggests that in addition to the eastward-moving MJO signal, the westward propagation of a convectively coupled equatorial Rossby wave is needed to explain the overall impact of the MJO on convection over West Africa. These results highlight the use of MJO events to potentially predict regional-scale anomalous convection and rainfall spells over West Africa with a time lag of approximately 15-20 days.

  19. Focused didactic training for skills lab student tutors – which techniques are considered helpful?

    PubMed Central

    Heni, Martin; Lammerding-Köppel, Maria; Celebi, Nora; Shiozawa, Thomas; Riessen, Reimer; Nikendei, Christoph; Weyrich, Peter

    2012-01-01

    Objective: Peer-assisted learning is widely used in medical education. However, little is known about an appropriate didactic preparation for peer tutors. We herein describe the development of a focused didactic training for skills lab tutors in Internal Medicine and report on a retrospective survey about the student tutors’ acceptance and the perceived transferability of attended didactic training modules. Methods: The course consisted of five training modules: ‘How to present and explain effectively’: the student tutors had to give a short presentation with subsequent video analysis and feedback in order to learn methods of effective presentation. ‘How to explain precisely’: Precise explanation techniques were trained by exercises of exact description of geometric figures and group feedback. ‘How to explain on impulse’: Spontaneous teaching presentations were simulated and feedback was given. ‘Peyton’s 4 Step Approach’: Peyton‘s Method for explanation of practical skills was introduced and trained by the participants. ‘How to deal with critical incidents’: Possibilities to deal with critical teaching situations were worked out in group sessions. Twenty-three student tutors participated in the retrospective survey by filling out an electronic questionnaire, after at least 6 months of teaching experience. Results: The exercise ‘How to present and explain effectively’ received the student tutors’ highest rating for their improvement of didactic qualification and was seen to be most easily transferable into the skills lab environment. This module was rated as the most effective module by nearly half of the participants. It was followed by ‘Peyton’s 4 Step Approach’ , though it was also seen to be the most delicate method in regard to its transfer into the skills lab owing to time concerns. However, it was considered to be highly effective. The other modules received lesser votes by the tutors as the most helpful exercise in improving their didactic qualification for skills lab teaching. Conclusion: We herein present a pilot concept for a focused didactic training of peer tutors and present results of a retrospective survey among our skills lab tutors about the distinct training modules. This report might help other faculties to design didactic courses for skills lab student tutors. PMID:22737196

  20. Focused didactic training for skills lab student tutors - which techniques are considered helpful?

    PubMed

    Heni, Martin; Lammerding-Köppel, Maria; Celebi, Nora; Shiozawa, Thomas; Riessen, Reimer; Nikendei, Christoph; Weyrich, Peter

    2012-01-01

    Peer-assisted learning is widely used in medical education. However, little is known about an appropriate didactic preparation for peer tutors. We herein describe the development of a focused didactic training for skills lab tutors in Internal Medicine and report on a retrospective survey about the student tutors' acceptance and the perceived transferability of attended didactic training modules. The course consisted of five training modules: 1. 'How to present and explain effectively': the student tutors had to give a short presentation with subsequent video analysis and feedback in order to learn methods of effective presentation. 2. 'How to explain precisely': Precise explanation techniques were trained by exercises of exact description of geometric figures and group feedback. 3. 'How to explain on impulse': Spontaneous teaching presentations were simulated and feedback was given. 4. 'Peyton's 4 Step Approach': Peyton's Method for explanation of practical skills was introduced and trained by the participants. 5. 'How to deal with critical incidents': Possibilities to deal with critical teaching situations were worked out in group sessions. Twenty-three student tutors participated in the retrospective survey by filling out an electronic questionnaire, after at least 6 months of teaching experience. The exercise 'How to present and explain effectively' received the student tutors' highest rating for their improvement of didactic qualification and was seen to be most easily transferable into the skills lab environment. This module was rated as the most effective module by nearly half of the participants. It was followed by 'Peyton's 4 Step Approach' , though it was also seen to be the most delicate method in regard to its transfer into the skills lab owing to time concerns. However, it was considered to be highly effective. The other modules received lesser votes by the tutors as the most helpful exercise in improving their didactic qualification for skills lab teaching. We herein present a pilot concept for a focused didactic training of peer tutors and present results of a retrospective survey among our skills lab tutors about the distinct training modules. This report might help other faculties to design didactic courses for skills lab student tutors.

  1. Development of a simulation of the surficial groundwater system for the CONUS

    NASA Astrophysics Data System (ADS)

    Zell, W.; Sanford, W. E.

    2016-12-01

    Water resource and environmental managers across the country face a variety of questions involving groundwater availability and/or groundwater transport pathways. Emerging management questions require prediction of groundwater response to changing climate regimes (e.g., how drought-induced water-table recession may degrade near-stream vegetation and result in increased wildfire risks), while existing questions can require identification of current groundwater contributions to surface water (e.g., groundwater linkages between landscape contaminant inputs and receiving streams may help explain in-stream phenomena such as fish intersex). At present, few national-coverage simulation tools exist to help characterize groundwater contributions to receiving streams and predict potential changes in base-flow regimes under changing climate conditions. We will describe the Phase 1 development of a simulation of the water table and shallow groundwater system for the entire CONUS. We use national-scale datasets such as the National Recharge Map and the Map Database for Surficial Materials in the CONUS to develop groundwater flow (MODFLOW) and transport (MODPATH) models that are calibrated against groundwater level and stream elevation data from NWIS and NHD, respectively. Phase 1 includes the development of a national transmissivity map for the surficial groundwater system and examines the impact of model-grid resolution on the simulated steady-state discharge network (and associated recharge areas) and base-flow travel time distributions for different HUC scales. In the course of developing the transmissivity map we show that transmissivity in fractured bedrock systems is dependent on depth to water. Subsequent phases of this work will simulate water table changes at a monthly time step (using MODIS-dependent recharge estimates) and serve as a critical complement to surface-water-focused USGS efforts to provide national coverage hydrologic modeling tools.

  2. Effect of Molecular Rotation on Charge Transport Phenomena

    NASA Astrophysics Data System (ADS)

    Garg, O. P.; Lamba, Vijay Kr; Kaushik, D. K.

    2015-12-01

    The study of electron transport properties of molecular systems could be explained on the basis of the Landauer formalism. Unfortunately, due to the complexity of the experimental setup, most of these measurements have no control over the details of the electrode geometry, rotation of molecules, variation in angle of contacts, effect of fano resonances associated with side groups attached to rigid backbones, which results in a spectrum of IV-characteristics. Theoretical models can therefore help to understand and helps to develop new applications such as molecular sensors, etc. Thus we used simulation methods that generate the required structural ensemble, which is then analyzed with Green’s function methods to characterize the electronic transport properties. In present work we had discussed applications of this approach to understand the conductance in molecular system in the direction of controlling electron transport through molecules and studied the effect of rotation of sandwiched molecule.

  3. Estimation of Transformation Temperatures in Ti-Ni-Pd Shape Memory Alloys

    NASA Astrophysics Data System (ADS)

    Narayana, P. L.; Kim, Seong-Woong; Hong, Jae-Keun; Reddy, N. S.; Yeom, Jong-Taek

    2018-03-01

    The present study focused on estimating the complex nonlinear relationship between the composition and phase transformation temperatures of Ti-Ni-Pd shape memory alloys by artificial neural networks (ANN). The ANN models were developed by using the experimental data of Ti-Ni-Pd alloys. It was found that the predictions are in good agreement with the trained and unseen test data of existing alloys. The developed model was able to simulate new virtual alloys to quantitatively estimate the effect of Ti, Ni, and Pd on transformation temperatures. The transformation temperature behavior of these virtual alloys is validated by conducting new experiments on the Ti-rich thin film that was deposited using multi target sputtering equipment. The transformation behavior of the film was measured by varying the composition with the help of aging treatment. The predicted trend of transformational temperatures was explained with the help of experimental results.

  4. Simulation of crash tests for high impact levels of a new bridge safety barrier

    NASA Astrophysics Data System (ADS)

    Drozda, Jiří; Rotter, Tomáš

    2017-09-01

    The purpose is to show the opportunity of a non-linear dynamic impact simulation and to explain the possibility of using finite element method (FEM) for developing new designs of safety barriers. The main challenge is to determine the means to create and validate the finite element (FE) model. The results of accurate impact simulations can help to reduce necessary costs for developing of a new safety barrier. The introductory part deals with the creation of the FE model, which includes the newly-designed safety barrier and focuses on the application of an experimental modal analysis (EMA). The FE model has been created in ANSYS Workbench and is formed from shell and solid elements. The experimental modal analysis, which was performed on a real pattern, was employed for measuring the modal frequencies and shapes. After performing the EMA, the FE mesh was calibrated after comparing the measured modal frequencies with the calculated ones. The last part describes the process of the numerical non-linear dynamic impact simulation in LS-DYNA. This simulation was validated after comparing the measured ASI index with the calculated ones. The aim of the study is to improve professional public knowledge about dynamic non-linear impact simulations. This should ideally lead to safer, more accurate and profitable designs.

  5. Permafrost carbon as a missing link to explain CO 2 changes during the last deglaciation

    NASA Astrophysics Data System (ADS)

    Crichton, K. A.; Bouttes, N.; Roche, D. M.; Chappellaz, J.; Krinner, G.

    2016-09-01

    The atmospheric concentration of CO2 increased from 190 to 280 ppm between the last glacial maximum 21,000 years ago and the pre-industrial era. This CO2 rise and its timing have been linked to changes in the Earth’s orbit, ice sheet configuration and volume, and ocean carbon storage. The ice-core record of δ13CO2 (refs ,) in the atmosphere can help to constrain the source of carbon, but previous modelling studies have failed to capture the evolution of δ13CO2 over this period. Here we show that simulations of the last deglaciation that include a permafrost carbon component can reproduce the ice core records between 21,000 and 10,000 years ago. We suggest that thawing permafrost, due to increasing summer insolation in the northern hemisphere, is the main source of CO2 rise between 17,500 and 15,000 years ago, a period sometimes referred to as the Mystery Interval. Together with a fresh water release into the North Atlantic, much of the CO2 variability associated with the Bølling-Allerod/Younger Dryas period ~15,000 to ~12,000 years ago can also be explained. In simulations of future warming we find that the permafrost carbon feedback increases global mean temperature by 10-40% relative to simulations without this feedback, with the magnitude of the increase dependent on the evolution of anthropogenic carbon emissions.

  6. [A new medical education using a lung sound auscultation simulator called "Mr. Lung"].

    PubMed

    Yoshii, Chiharu; Anzai, Takashi; Yatera, Kazuhiro; Kawajiri, Tatsunori; Nakashima, Yasuhide; Kido, Masamitsu

    2002-09-01

    We developed a lung sound auscultation simulator "Mr. Lung" in 2001. To improve the auscultation skills of lung sounds, we utilized this new device in our educational training facility. From June 2001 to March 2002, we used "Mr. Lung" for our small group training in which one hundred of the fifth year medical students were divided into small groups from which one group was taught every other week. The class consisted of ninety-minute training periods for auscultation of lung sounds. At first, we explained the classification of lung sounds, and then auscultation tests were performed. Namely, students listened to three cases of abnormal or adventitious lung sounds on "Mr. Lung" through their stethoscopes. Next they answered questions corresponding to the portion and quality of the sounds. Then, we explained the correct answers and how to differentiate lung sounds on "Mr. Lung". Additionally, at the beginning and the end of the lecture, five degrees of self-assessment for the auscultation of the lung sounds were performed. The ratio of correct answers for lung sounds were 36.9% for differences between bilateral lung sounds, 52.5% for coarse crackles, 34.1% for fine crackles, 69.2% for wheezes, 62.1% for rhonchi and 22.2% for stridor. Self-assessment scores were significantly higher after the class than before. The ratio of correct lung sound answers was surprisingly low among medical students. We believe repetitive auscultation of the simulator to be extremely helpful for medical education.

  7. The Motor System: The Whole and its Parts

    PubMed Central

    Otten, E.

    2001-01-01

    Our knowledge of components of the human motor system has been growing steadily, but our understanding of its integration into a system is lagging behind. It is suggested that a combination of measurements of forces and movements of the motor system in a functionally meaningful environment in conjunction with computer simulations of the motor system may help us in understanding motor system properties. Neurotrauma can be seen as a natural deviation, with recovery as a slow path to yet another deviant state of the motor system. In that form they may be useful in explaining the close interaction between form and function of the human motor system. PMID:11530882

  8. Coarse-Grained Models for Protein-Cell Membrane Interactions

    PubMed Central

    Bradley, Ryan; Radhakrishnan, Ravi

    2015-01-01

    The physiological properties of biological soft matter are the product of collective interactions, which span many time and length scales. Recent computational modeling efforts have helped illuminate experiments that characterize the ways in which proteins modulate membrane physics. Linking these models across time and length scales in a multiscale model explains how atomistic information propagates to larger scales. This paper reviews continuum modeling and coarse-grained molecular dynamics methods, which connect atomistic simulations and single-molecule experiments with the observed microscopic or mesoscale properties of soft-matter systems essential to our understanding of cells, particularly those involved in sculpting and remodeling cell membranes. PMID:26613047

  9. What determines the direction of minimum variance of the magnetic field fluctuations in the solar wind?

    NASA Technical Reports Server (NTRS)

    Grappin, R.; Velli, M.

    1995-01-01

    The solar wind is not an isotropic medium; two symmetry axis are provided, first the radial direction (because the mean wind is radial) and second the spiral direction of the mean magnetic field, which depends on heliocentric distance. Observations show very different anisotropy directions, depending on the frequency waveband; while the large-scale velocity fluctuations are essentially radial, the smaller scale magnetic field fluctuations are mostly perpendicular to the mean field direction, which is not the expected linear (WkB) result. We attempt to explain how these properties are related, with the help of numerical simulations.

  10. Analysis of polarized-light effects in glass-promoting solutions with applications to cryopreservation and organ banking.

    PubMed

    Solanki, Prem K; Rabin, Yoed

    2018-01-01

    This study presents experimental results and an analysis approach for polarized light effects associated with thermomechanical stress during cooling of glass promoting solutions, with applications to cryopreservation and tissue banking in a process known as vitrification. Polarized light means have been previously integrated into the cryomacroscope-a visualization device to detect physical effects associated with cryopreservation success, such as crystallization, fracture formation, and contamination. The experimental study concerns vitrification in a cuvette, which is a rectangular container. Polarized light modeling in the cuvette is based on subdividing the tridimensional (3D) domain into a series of planar (2D) problems, for which a mathematical solution is available in the literature. The current analysis is based on tracking the accumulated changes in light polarization and magnitude, as it passes through the sequence of planar problems. Results of this study show qualitative agreement in light intensity history and distribution between experimental data and simulated results. The simulated results help explaining differences between 2D and 3D effects in photoelasticity, most notably, the counterintuitive observation that high stress areas may correlate with low light intensity regions based on the particular experimental conditions. Finally, it is suggested that polarized-light analysis must always be accompanied by thermomechanical stress modeling in order to explain 3D effects.

  11. Analysis of polarized-light effects in glass-promoting solutions with applications to cryopreservation and organ banking

    PubMed Central

    2018-01-01

    This study presents experimental results and an analysis approach for polarized light effects associated with thermomechanical stress during cooling of glass promoting solutions, with applications to cryopreservation and tissue banking in a process known as vitrification. Polarized light means have been previously integrated into the cryomacroscope—a visualization device to detect physical effects associated with cryopreservation success, such as crystallization, fracture formation, and contamination. The experimental study concerns vitrification in a cuvette, which is a rectangular container. Polarized light modeling in the cuvette is based on subdividing the tridimensional (3D) domain into a series of planar (2D) problems, for which a mathematical solution is available in the literature. The current analysis is based on tracking the accumulated changes in light polarization and magnitude, as it passes through the sequence of planar problems. Results of this study show qualitative agreement in light intensity history and distribution between experimental data and simulated results. The simulated results help explaining differences between 2D and 3D effects in photoelasticity, most notably, the counterintuitive observation that high stress areas may correlate with low light intensity regions based on the particular experimental conditions. Finally, it is suggested that polarized-light analysis must always be accompanied by thermomechanical stress modeling in order to explain 3D effects. PMID:29912973

  12. Anatomy of the binary black hole recoil: A multipolar analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schnittman, Jeremy D.; Buonanno, Alessandra; Meter, James R. van

    2008-02-15

    We present a multipolar analysis of the gravitational recoil computed in recent numerical simulations of binary black hole coalescence, for both unequal masses and nonzero, nonprecessing spins. We show that multipole moments up to and including l=4 are sufficient to accurately reproduce the final recoil velocity (within {approx_equal}2%) and that only a few dominant modes contribute significantly to it (within {approx_equal}5%). We describe how the relative amplitudes, and more importantly, the relative phases, of these few modes control the way in which the recoil builds up throughout the inspiral, merger, and ringdown phases. We also find that the numerical resultsmore » can be reproduced by an 'effective Newtonian' formula for the multipole moments obtained by replacing the radial separation in the Newtonian formulas with an effective radius computed from the numerical data. Beyond the merger, the numerical results are reproduced by a superposition of three Kerr quasinormal modes. Analytic formulas, obtained by expressing the multipole moments in terms of the fundamental quasinormal modes of a Kerr black hole, are able to explain the onset and amount of 'antikick' for each of the simulations. Lastly, we apply this multipolar analysis to help explain the remarkable difference between the amplitudes of planar and nonplanar kicks for equal-mass spinning black holes.« less

  13. New insight of Arctic cloud parameterization from regional climate model simulations, satellite-based, and drifting station data

    NASA Astrophysics Data System (ADS)

    Klaus, D.; Dethloff, K.; Dorn, W.; Rinke, A.; Wu, D. L.

    2016-05-01

    Cloud observations from the CloudSat and CALIPSO satellites helped to explain the reduced total cloud cover (Ctot) in the atmospheric regional climate model HIRHAM5 with modified cloud physics. Arctic climate conditions are found to be better reproduced with (1) a more efficient Bergeron-Findeisen process and (2) a more generalized subgrid-scale variability of total water content. As a result, the annual cycle of Ctot is improved over sea ice, associated with an almost 14% smaller area average than in the control simulation. The modified cloud scheme reduces the Ctot bias with respect to the satellite observations. Except for autumn, the cloud reduction over sea ice improves low-level temperature profiles compared to drifting station data. The HIRHAM5 sensitivity study highlights the need for improving accuracy of low-level (<700 m) cloud observations, as these clouds exert a strong impact on the near-surface climate.

  14. Translating cognitive neuroscience to the driver’s operational environment: a neuroergonomics approach

    PubMed Central

    Lees, Monica N.; Cosman, Joshua D.; Lee, John D.; Rizzo, Matthew; Fricke, Nicola

    2012-01-01

    Neuroergonomics provides a multidisciplinary translational approach that merges elements of neuroscience, human factors, cognitive psychology, and ergonomics to study brain structure and function in everyday environments. Driving safety, particularly that of older drivers with cognitive impairments, is a fruitful application domain for neuroergonomics. Driving makes demands on multiple cognitive processes that are often studied in isolation and so presents a useful challenge in generalizing findings from controlled laboratory tasks to predict safety outcomes. Neurology and the cognitive sciences help explain the mechanisms of cognitive breakdowns that undermine driving safety. Ergonomics complements this explanation with the tools for systematically exploring the various layers of complexity that define the activity of driving. A variety of tools, such as part task simulators, driving simulators, and instrumented vehicles provide a window into cognition in the natural settings needed to assess the generalizability of laboratory findings and can provide an array of potential interventions to increase safety. PMID:21291157

  15. Identification of groundwater parameters at Columbus, Mississippi, using a 3D inverse flow and transport model

    USGS Publications Warehouse

    Barlebo, H.C.; Rosbjerg, D.; Hill, M.C.

    1996-01-01

    An extensive amount of data including hydraulic heads, hydraulic conductivities and concentrations of several solutes from controlled injections have been collected during the MADE 1 and MADE 2 experiments at a heterogeneous site near Columbus, Mississippi. In this paper the use of three-dimensional inverse groundwater models including simultaneous estimation of flow and transport parameters is proposed to help identify the dominant characteristics at the site. Simulations show that using a hydraulic conductivity distribution obtained from 2187 borehole flowmeter tests directly in the model produces poor matches to the measured hydraulic heads and tritium concentrations. Alternatively, time averaged hydraulic head maps are used to define zones of constant hydraulic conductivity to be estimated. Preliminary simulations suggest that in the case of conservative transport many, but not all, of the major plume characteristics can be explained by large-scale heterogeneity in recharge and hydraulic conductivity.

  16. Simulation Study of Magnetic Fields Generated by the Electromagnetic Filamentation Instability

    NASA Technical Reports Server (NTRS)

    Nishikawa, K.-I.; Ramirez-Ruiz, E.; Hardee, P.; Hededal, C. B.; Mizuno, Y.; Fishman, G. J.

    2007-01-01

    We have investigated the effects of plasma instabilities driven by rapid e(sup plus or minus) pair cascades, which arise in the environment of GRB sources as a result of back-scattering of a seed fraction of the original spectrum. The injection of e(sup plus or minus) pairs induces strong streaming motions in the ambient medium. One therefore expects the pair-enriched medium ahead of the forward shock to be strongly sheared on length scales comparable to the radiation front thickness. Using three-dimensional particle-in-cell simulations, we show that plasma instabilities driven by these streaming e(sup plus or minus) pairs are responsible for the excitation of near-equipartition, turbulent magnetic fields. Our results reveal the importance of the electromagnetic filamentation instability in ensuring an effective coupling between e(sup plus or minus) pairs and ions, and may help explain the origin of large upstream fields in GRB shocks.

  17. Laboratory Studies of Anomalous Entrainment in Cumulus Cloud Flows

    NASA Astrophysics Data System (ADS)

    Diwan, Sourabh S.; Narasimha, Roddam; Bhat, G. S.; Sreenivas, K. R.

    2011-12-01

    Entrainment in cumulus clouds has been a subject of investigation for the last sixty years, and continues to be a central issue in current research. The development of a laboratory facility that can simulate cumulus cloud evolution enables us to shed light on the problem. The apparatus for the purpose is based on a physical model of cloud flow as a plume with off-source diabatic heating that is dynamically similar to the effect of latent-heat release in natural clouds. We present a critical review of the experimental data so far obtained in such facilities on the variation of the entrainment coefficient in steady diabatic jets and plumes. Although there are some unexplained differences among different data sets, the dominant trend of the results compares favourably with recent numerical simulations on steady-state deep convection, and helps explain certain puzzles in the fluid dynamics of clouds.

  18. The impact of confounder selection in propensity scores when applied to prospective cohort studies in pregnancy.

    PubMed

    Xu, Ronghui; Hou, Jue; Chambers, Christina D

    2018-06-01

    Our work was motivated by small cohort studies on the risk of birth defects in infants born to pregnant women exposed to medications. We controlled for confounding using propensity scores (PS). The extremely rare events setting renders the matching or stratification infeasible. In addition, the PS itself may be formed via different approaches to select confounders from a relatively long list of potential confounders. We carried out simulation experiments to compare different combinations of approaches: IPW or regression adjustment, with 1) including all potential confounders without selection, 2) selection based on univariate association between the candidate variable and the outcome, 3) selection based on change in effects (CIE). The simulation showed that IPW without selection leads to extremely large variances in the estimated odds ratio, which help to explain the empirical data analysis results that we had observed. Copyright © 2018 Elsevier Inc. All rights reserved.

  19. Influence of plasma shock wave on the morphology of laser drilling in different environments

    NASA Astrophysics Data System (ADS)

    Zhai, Zhaoyang; Wang, Wenjun; Mei, Xuesong; Wang, Kedian; Yang, Huizhu

    2017-05-01

    Nanosecond pulse laser was used to study nickel-based alloy drilling and compare processing results of microholes in air environment and water environment. Through analysis and comparison, it's found that environmental medium had obvious influence on morphology of laser drilling. High-speed camera was used to shoot plasma morphology during laser drilling process, theoretical formula was used to calculate boundary dimension of plasma and shock wave velocity, and finally parameters were substituted into computational fluid dynamics simulation software to obtain solutions. Obtained analysis results could intuitively explain different morphological features and forming reasons between laser drilling in air environment and water environment in the experiment from angle of plasma shock waves. By comparing simulation results and experimental results, it could help to get an understanding of formation mechanism of microhole morphology, thus providing basis for further improving process optimization of laser drilling quality.

  20. Sonoporation at Small and Large Length Scales: Effect of Cavitation Bubble Collapse on Membranes.

    PubMed

    Fu, Haohao; Comer, Jeffrey; Cai, Wensheng; Chipot, Christophe

    2015-02-05

    Ultrasound has emerged as a promising means to effect controlled delivery of therapeutic agents through cell membranes. One possible mechanism that explains the enhanced permeability of lipid bilayers is the fast contraction of cavitation bubbles produced on the membrane surface, thereby generating large impulses, which, in turn, enhance the permeability of the bilayer to small molecules. In the present contribution, we investigate the collapse of bubbles of different diameters, using atomistic and coarse-grained molecular dynamics simulations to calculate the force exerted on the membrane. The total impulse can be computed rigorously in numerical simulations, revealing a superlinear dependence of the impulse on the radius of the bubble. The collapse affects the structure of a nearby immobilized membrane, and leads to partial membrane invagination and increased water permeation. The results of the present study are envisioned to help optimize the use of ultrasound, notably for the delivery of drugs.

  1. Reproductive constraints, direct fitness and indirect fitness benefits explain helping behaviour in the primitively eusocial wasp, Polistes canadensis.

    PubMed

    Sumner, Seirian; Kelstrup, Hans; Fanelli, Daniele

    2010-06-07

    A key step in the evolution of sociality is the abandonment of independent breeding in favour of helping. In cooperatively breeding vertebrates and primitively eusocial insects, helpers are capable of leaving the group and reproducing independently, and yet many do not. A fundamental question therefore is why do helpers help? Helping behaviour may be explained by constraints on independent reproduction and/or benefits to individuals from helping. Here, we examine simultaneously the reproductive constraints and fitness benefits underlying helping behaviour in a primitively eusocial paper wasp. We gave 31 helpers the opportunity to become egg-layers on their natal nests by removing nestmates. This allowed us to determine whether helpers are reproductively constrained in any way. We found that age strongly influenced whether an ex-helper could become an egg-layer, such that young ex-helpers could become egg-layers while old ex-helpers were less able. These differential reproductive constraints enabled us to make predictions about the behaviours of ex-helpers, depending on the relative importance of direct and indirect fitness benefits. We found little evidence that indirect fitness benefits explain helping behaviour, as 71 per cent of ex-helpers left their nests before the end of the experiment. In the absence of reproductive constraints, however, young helpers value direct fitness opportunities over indirect fitness. We conclude that a combination of reproductive constraints and potential for future direct reproduction explain helping behaviour in this species. Testing several competing explanations for helping behaviour simultaneously promises to advance our understanding of social behaviour in animal groups.

  2. Can theories of visual representation help to explain asymmetries in amygdala function?

    PubMed

    McMenamin, Brenton W; Marsolek, Chad J

    2013-06-01

    Emotional processing differs between the left and right hemispheres of the brain, and functional differences have been reported more specifically between the left and right amygdalae, subcortical structures heavily implicated in emotional processing. However, the empirical pattern of amygdalar asymmetries is inconsistent with extant theories of emotional asymmetries. Here we review this discrepancy, and we hypothesize that hemispheric differences in visual object processing help to explain the previously reported functional differences between the left and right amygdalae. The implication that perceptual factors play a large role in determining amygdalar asymmetries may help to explain amygdalar dysfunction in the development and maintenance of posttraumatic stress disorder.

  3. Negotiation and appeasement can be more effective drivers of sociality than kin selection.

    PubMed

    Quiñones, Andrés E; van Doorn, G Sander; Pen, Ido; Weissing, Franz J; Taborsky, Michael

    2016-02-05

    Two alternative frameworks explain the evolution of cooperation in the face of conflicting interests. Conflicts can be alleviated by kinship, the alignment of interests by virtue of shared genes, or by negotiation strategies, allowing mutually beneficial trading of services or commodities. Although negotiation often occurs in kin-structured populations, the interplay of kin- and negotiation-based mechanisms in the evolution of cooperation remains an unresolved issue. Inspired by the biology of a cooperatively breeding fish, we developed an individual-based simulation model to study the evolution of negotiation-based cooperation in relation to different levels of genetic relatedness. We show that the evolution of negotiation strategies leads to an equilibrium where subordinates appease dominants by conditional cooperation, resulting in high levels of help and low levels of aggression. This negotiation-based equilibrium can be reached both in the absence of relatedness and in a kin-structured population. However, when relatedness is high, evolution often ends up in an alternative equilibrium where subordinates help their kin unconditionally. The level of help at this kin-selected equilibrium is considerably lower than at the negotiation-based equilibrium, and it corresponds to a level reached when responsiveness is prevented from evolving in the simulations. A mathematical invasion analysis reveals that, quite generally, the alignment of payoffs due to the relatedness of interaction partners tends to impede selection for harsh but effective punishment of defectors. Hence kin structure will often hamper rather than facilitate the evolution of productive cooperation. © 2016 The Author(s).

  4. Negotiation and appeasement can be more effective drivers of sociality than kin selection

    PubMed Central

    van Doorn, G. Sander; Pen, Ido; Weissing, Franz J.

    2016-01-01

    Two alternative frameworks explain the evolution of cooperation in the face of conflicting interests. Conflicts can be alleviated by kinship, the alignment of interests by virtue of shared genes, or by negotiation strategies, allowing mutually beneficial trading of services or commodities. Although negotiation often occurs in kin-structured populations, the interplay of kin- and negotiation-based mechanisms in the evolution of cooperation remains an unresolved issue. Inspired by the biology of a cooperatively breeding fish, we developed an individual-based simulation model to study the evolution of negotiation-based cooperation in relation to different levels of genetic relatedness. We show that the evolution of negotiation strategies leads to an equilibrium where subordinates appease dominants by conditional cooperation, resulting in high levels of help and low levels of aggression. This negotiation-based equilibrium can be reached both in the absence of relatedness and in a kin-structured population. However, when relatedness is high, evolution often ends up in an alternative equilibrium where subordinates help their kin unconditionally. The level of help at this kin-selected equilibrium is considerably lower than at the negotiation-based equilibrium, and it corresponds to a level reached when responsiveness is prevented from evolving in the simulations. A mathematical invasion analysis reveals that, quite generally, the alignment of payoffs due to the relatedness of interaction partners tends to impede selection for harsh but effective punishment of defectors. Hence kin structure will often hamper rather than facilitate the evolution of productive cooperation. PMID:26729929

  5. Simulating the role of visual selective attention during the development of perceptual completion

    PubMed Central

    Schlesinger, Matthew; Amso, Dima; Johnson, Scott P.

    2014-01-01

    We recently proposed a multi-channel, image-filtering model for simulating the development of visual selective attention in young infants (Schlesinger, Amso & Johnson, 2007). The model not only captures the performance of 3-month-olds on a visual search task, but also implicates two cortical regions that may play a role in the development of visual selective attention. In the current simulation study, we used the same model to simulate 3-month-olds’ performance on a second measure, the perceptual unity task. Two parameters in the model – corresponding to areas in the occipital and parietal cortices – were systematically varied while the gaze patterns produced by the model were recorded and subsequently analyzed. Three key findings emerged from the simulation study. First, the model successfully replicated the performance of 3-month-olds on the unity perception task. Second, the model also helps to explain the improved performance of 2-month-olds when the size of the occluder in the unity perception task is reduced. Third, in contrast to our previous simulation results, variation in only one of the two cortical regions simulated (i.e. recurrent activity in posterior parietal cortex) resulted in a performance pattern that matched 3-month-olds. These findings provide additional support for our hypothesis that the development of perceptual completion in early infancy is promoted by progressive improvements in visual selective attention and oculomotor skill. PMID:23106728

  6. Simulating the role of visual selective attention during the development of perceptual completion.

    PubMed

    Schlesinger, Matthew; Amso, Dima; Johnson, Scott P

    2012-11-01

    We recently proposed a multi-channel, image-filtering model for simulating the development of visual selective attention in young infants (Schlesinger, Amso & Johnson, 2007). The model not only captures the performance of 3-month-olds on a visual search task, but also implicates two cortical regions that may play a role in the development of visual selective attention. In the current simulation study, we used the same model to simulate 3-month-olds' performance on a second measure, the perceptual unity task. Two parameters in the model - corresponding to areas in the occipital and parietal cortices - were systematically varied while the gaze patterns produced by the model were recorded and subsequently analyzed. Three key findings emerged from the simulation study. First, the model successfully replicated the performance of 3-month-olds on the unity perception task. Second, the model also helps to explain the improved performance of 2-month-olds when the size of the occluder in the unity perception task is reduced. Third, in contrast to our previous simulation results, variation in only one of the two cortical regions simulated (i.e. recurrent activity in posterior parietal cortex) resulted in a performance pattern that matched 3-month-olds. These findings provide additional support for our hypothesis that the development of perceptual completion in early infancy is promoted by progressive improvements in visual selective attention and oculomotor skill. © 2012 Blackwell Publishing Ltd.

  7. Explaining Helping Behavior in a Cooperative Learning Classroom Setting Using Attribution Theory

    ERIC Educational Resources Information Center

    Ahles, Paula M.; Contento, Jann M.

    2006-01-01

    This recently completed study examined whether attribution theory can explain helping behavior in an interdependent classroom environment that utilized a cooperative-learning model. The study focused on student participants enrolled in 6 community college communication classes taught by the same instructor. Three levels of cooperative-learning…

  8. Strong control of Southern Ocean cloud reflectivity by ice-nucleating particles.

    PubMed

    Vergara-Temprado, Jesús; Miltenberger, Annette K; Furtado, Kalli; Grosvenor, Daniel P; Shipway, Ben J; Hill, Adrian A; Wilkinson, Jonathan M; Field, Paul R; Murray, Benjamin J; Carslaw, Ken S

    2018-03-13

    Large biases in climate model simulations of cloud radiative properties over the Southern Ocean cause large errors in modeled sea surface temperatures, atmospheric circulation, and climate sensitivity. Here, we combine cloud-resolving model simulations with estimates of the concentration of ice-nucleating particles in this region to show that our simulated Southern Ocean clouds reflect far more radiation than predicted by global models, in agreement with satellite observations. Specifically, we show that the clouds that are most sensitive to the concentration of ice-nucleating particles are low-level mixed-phase clouds in the cold sectors of extratropical cyclones, which have previously been identified as a main contributor to the Southern Ocean radiation bias. The very low ice-nucleating particle concentrations that prevail over the Southern Ocean strongly suppress cloud droplet freezing, reduce precipitation, and enhance cloud reflectivity. The results help explain why a strong radiation bias occurs mainly in this remote region away from major sources of ice-nucleating particles. The results present a substantial challenge to climate models to be able to simulate realistic ice-nucleating particle concentrations and their effects under specific meteorological conditions. Copyright © 2018 the Author(s). Published by PNAS.

  9. RF breakdown in "cold" slow wave structures operating at travelling wave mode of TM01

    NASA Astrophysics Data System (ADS)

    Yuan, Yuzhang; Zhang, Jun; Zhong, Huihuang; Zhang, Dian; Bai, Zhen; Zhu, Danni

    2018-01-01

    RF breakdown experiments and simulations in "cold" slow wave structures (SWSs) are executed. All the SWSs are designed as traveling wave structures, which operate at the π/2 mode of TM01 waves. The experimental results indicate that the input microwave energy is mainly absorbed, not reflected by the RF breakdown process in traveling wave SWSs. Both larger magnitude of Es-max and more numbers of periods of SWSs aggravate the microwave absorption in the breakdown process and bring about a shorter transmission pulse width. We think that the critical surface E-field of the multi-period SWSs is 1 MV/cm. However, little correlation between RF breakdown effects and Bext is observed in the experiments. The simulation conditions are coincident with the experimental setup. Explosive emissions of electrons in the rounded corner of SWSs together with the ionization of the gas layer close to it supply the breakdown plasma. The gas layer consists of water vapor and hydrogen gas and has a pressure of 1 Pa. Different kinds of circumstances of SWSs are simulated. We mainly concern about the characteristic of the plasma and its influence on microwave power. Comprehensive simulation results are obtained. The simulation results match the experimental results basically and are helpful in explaining the RF breakdown phenomenon physically.

  10. Episodic accretion in binary protostars emerging from self-gravitating solar mass cores

    NASA Astrophysics Data System (ADS)

    Riaz, R.; Vanaverbeke, S.; Schleicher, D. R. G.

    2018-06-01

    Observations show a large spread in the luminosities of young protostars, which are frequently explained in the context of episodic accretion. We tested this scenario with numerical simulations that follow the collapse of a solar mass molecular cloud using the GRADSPH code, thereby varying the strength of the initial perturbations and temperature of the cores. A specific emphasis of this paper is to investigate the role of binaries and multiple systems in the context of episodic accretion and to compare their evolution to the evolution in isolated fragments. Our models form a variety of low-mass protostellar objects including single, binary, and triple systems in which binaries are more active in exhibiting episodic accretion than isolated protostars. We also find a general decreasing trend in the average mass accretion rate over time, suggesting that the majority of the protostellar mass is accreted within the first 105 years. This result can potentially help to explain the surprisingly low average luminosities in the majority of the protostellar population.

  11. Understanding and planning ecological restoration of plant-pollinator networks.

    PubMed

    Devoto, Mariano; Bailey, Sallie; Craze, Paul; Memmott, Jane

    2012-04-01

    Theory developed from studying changes in the structure and function of communities during natural or managed succession can guide the restoration of particular communities. We constructed 30 quantitative plant-flower visitor networks along a managed successional gradient to identify the main drivers of change in network structure. We then applied two alternative restoration strategies in silico (restoring for functional complementarity or redundancy) to data from our early successional plots to examine whether different strategies affected the restoration trajectories. Changes in network structure were explained by a combination of age, tree density and variation in tree diameter, even when variance explained by undergrowth structure was accounted for first. A combination of field data, a network approach and numerical simulations helped to identify which species should be given restoration priority in the context of different restoration targets. This combined approach provides a powerful tool for directing management decisions, particularly when management seeks to restore or conserve ecosystem function. © 2012 Blackwell Publishing Ltd/CNRS.

  12. Spatial Distribution of Large Cloud Drops

    NASA Technical Reports Server (NTRS)

    Marshak, A.; Knyazikhin, Y.; Larsen, M.; Wiscombe, W.

    2004-01-01

    By analyzing aircraft measurements of individual drop sizes in clouds, we have shown in a companion paper (Knyazikhin et al., 2004) that the probability of finding a drop of radius r at a linear scale l decreases as l(sup D(r)) where 0 less than or equal to D(r) less than or equal to 1. This paper shows striking examples of the spatial distribution of large cloud drops using models that simulate the observed power laws. In contrast to currently used models that assume homogeneity and therefore a Poisson distribution of cloud drops, these models show strong drop clustering, the more so the larger the drops. The degree of clustering is determined by the observed exponents D(r). The strong clustering of large drops arises naturally from the observed power-law statistics. This clustering has vital consequences for rain physics explaining how rain can form so fast. It also helps explain why remotely sensed cloud drop size is generally biased and why clouds absorb more sunlight than conventional radiative transfer models predict.

  13. Kinship, parental manipulation and evolutionary origins of eusociality

    PubMed Central

    Kapheim, Karen M.; Nonacs, Peter; Smith, Adam R.; Wayne, Robert K.; Wcislo, William T.

    2015-01-01

    One of the hallmarks of eusociality is that workers forego their own reproduction to assist their mother in raising siblings. This seemingly altruistic behaviour may benefit workers if gains in indirect fitness from rearing siblings outweigh the loss of direct fitness. If worker presence is advantageous to mothers, however, eusociality may evolve without net benefits to workers. Indirect fitness benefits are often cited as evidence for the importance of inclusive fitness in eusociality, but have rarely been measured in natural populations. We compared inclusive fitness of alternative social strategies in the tropical sweat bee, Megalopta genalis, for which eusociality is optional. Our results show that workers have significantly lower inclusive fitness than females that found their own nests. In mathematical simulations based on M. genalis field data, eusociality cannot evolve with reduced intra-nest relatedness. The simulated distribution of alternative social strategies matched observed distributions of M. genalis social strategies when helping behaviour was simulated as the result of maternal manipulation, but not as worker altruism. Thus, eusociality in M. genalis is best explained through kin selection, but the underlying mechanism is likely maternal manipulation. PMID:25694620

  14. A Measurement and Simulation Based Methodology for Cache Performance Modeling and Tuning

    NASA Technical Reports Server (NTRS)

    Waheed, Abdul; Yan, Jerry; Saini, Subhash (Technical Monitor)

    1998-01-01

    We present a cache performance modeling methodology that facilitates the tuning of uniprocessor cache performance for applications executing on shared memory multiprocessors by accurately predicting the effects of source code level modifications. Measurements on a single processor are initially used for identifying parts of code where cache utilization improvements may significantly impact the overall performance. Cache simulation based on trace-driven techniques can be carried out without gathering detailed address traces. Minimal runtime information for modeling cache performance of a selected code block includes: base virtual addresses of arrays, virtual addresses of variables, and loop bounds for that code block. Rest of the information is obtained from the source code. We show that the cache performance predictions are as reliable as those obtained through trace-driven simulations. This technique is particularly helpful to the exploration of various "what-if' scenarios regarding the cache performance impact for alternative code structures. We explain and validate this methodology using a simple matrix-matrix multiplication program. We then apply this methodology to predict and tune the cache performance of two realistic scientific applications taken from the Computational Fluid Dynamics (CFD) domain.

  15. Simulating indoor concentrations of NO(2) and PM(2.5) in multifamily housing for use in health-based intervention modeling.

    PubMed

    Fabian, P; Adamkiewicz, G; Levy, J I

    2012-02-01

    Residents of low-income multifamily housing can have elevated exposures to multiple environmental pollutants known to influence asthma. Simulation models can characterize the health implications of changing indoor concentrations, but quantifying the influence of interventions on concentrations is challenging given complex airflow and source characteristics. In this study, we simulated concentrations in a prototype multifamily building using CONTAM, a multizone airflow and contaminant transport program. Contaminants modeled included PM(2.5) and NO(2) , and parameters included stove use, presence and operability of exhaust fans, smoking, unit level, and building leakiness. We developed regression models to explain variability in CONTAM outputs for individual sources, in a manner that could be utilized in simulation modeling of health outcomes. To evaluate our models, we generated a database of 1000 simulated households with characteristics consistent with Boston public housing developments and residents and compared the predicted levels of NO(2) and PM(2.5) and their correlates with the literature. Our analyses demonstrated that CONTAM outputs could be readily explained by available parameters (R(2) between 0.89 and 0.98 across models), but that one-compartment box models would mischaracterize concentrations and source contributions. Our study quantifies the key drivers for indoor concentrations in multifamily housing and helps to identify opportunities for interventions. Many low-income urban asthmatics live in multifamily housing that may be amenable to ventilation-related interventions such as weatherization or air sealing, wall and ceiling hole repairs, and exhaust fan installation or repair, but such interventions must be designed carefully given their cost and their offsetting effects on energy savings as well as indoor and outdoor pollutants. We developed models to take into account the complex behavior of airflow patterns in multifamily buildings, which can be used to identify and evaluate environmental and non-environmental interventions targeting indoor air pollutants which can trigger asthma exacerbations. © 2011 John Wiley & Sons A/S.

  16. Saturn's F Ring Core: Calm in the Midst of Chaos

    NASA Technical Reports Server (NTRS)

    Cuzzi, J. N.; Whizin, A. D.; Hogan, R. C.; Dobrovolskis, A. R.; Dones, L.; Showalter. M. R.; Colwell, J. E.; Scargle, J. D.

    2013-01-01

    The long-term stability of the narrow F Ring core has been hard to understand. Instead of acting as "shepherds", Prometheus and Pandora together stir the vast preponderance of the region into a chaotic state, consistent with the orbits of newly discovered objects like S/2004S6. We show how a comb of very narrow radial locations of high stability in semimajor axis is embedded within this otherwise chaotic region. The stability of these semimajor axes relies fundamentally on the unusual combination of rapid apse precession and long synodic period which characterizes the region. This situation allows stable "antiresonances" to fall on or very close to traditional Lindblad resonances which, under more common circumstances, are destabilizing. We present numerical integrations of tens of thousands of test particles over tens of thousands of Prometheus orbits that map out the effect. The stable antiresonance zones are most stable in a subset of the region where Prometheus first-order resonances are least cluttered by Pandora resonances. This region of optimum stability is paradoxically closer to Prometheus than a location more representative of "torque balance", helping explain a longstanding paradox. One stable zone corresponds closely to the currently observed semimajor axis of the F Ring core. While the model helps explain the stability of the narrow F Ring core, it does not explain why the F Ring material all shares a common apse longitude; we speculate that collisional damping at the preferred semimajor axis (not included in the current simulations) may provide that final step. Essentially, we find that the F Ring core is not confined by a combination of Prometheus and Pandora, but a combination of Prometheus and precession.

  17. Simulation of B Cell Affinity Maturation Explains Enhanced Antibody Cross-Reactivity Induced by the Polyvalent Malaria Vaccine AMA1

    DTIC Science & Technology

    2014-07-01

    cell decisions in lymphoid tissue. Mol. Cell . Biol. 28: 4040–4051. 22. Kosmrlj, A., A. K. Jha, E. S. Huseby, M. Kardar, and A. K. Chakraborty. 2008. How...JUL 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE Simulation of B Cell Affinity Maturation Explains...8-98) Prescribed by ANSI Std Z39-18 The Journal of Immunology Simulation of B Cell Affinity Maturation Explains Enhanced Antibody Cross-Reactivity

  18. Reviews

    NASA Astrophysics Data System (ADS)

    2007-01-01

    WE RECOMMEND The Cloudspotter's Guide Not a reference book, but well written and pleasing to read. The Virtual Physical Laboratory This free CD contains useful simulations for the classroom. The Science of Ice Cream A comprehensive text suitable for A-level students. Singapore Science Centre A must-see centre for physics enthusiasts in Singapore. Weatherbytes A DVD containing five programmes explaining the weather. WORTH A LOOK How Teachers Learn Best, An Ongoing Professional Development Model A book to help you spot a school with good CPD opportunities. Fifex LED Array An expensive but well-made LED array. School Stop-Clock A sturdy clock suitable for a variety of timing experiments. WEB WATCH A collection of websites related to light.

  19. An application for multi-person task synchronization

    NASA Technical Reports Server (NTRS)

    Brown, Robert L.; Doyle, Dee

    1990-01-01

    Computer applications are studied that will enable a group of people to synchronize their actions when following a predefined task sequence. It is assumed that the people involved only have computer workstations available to them for communication. Hence, the approach is to study how the computer can be used to help a group remain synchronized. A series of applications were designed and developed that can be used as vehicles for experimentation. An example of how this technique can be used for a remote coaching capability is explained in a report describing an experiment that simulated a Life Sciences experiment on-board Space Station Freedom, with a ground based principal investigator providing the expertise by coaching the on-orbit mission specialist.

  20. Switching behavior and novel stable states of magnetic hexagonal nanorings

    NASA Astrophysics Data System (ADS)

    Yasir Rafique, M.; Pan, Liqing; Guo, Zhengang

    2017-06-01

    Micromagnetic simulations for Cobalt hexagonal shape nanorings show onion (O) and vortex state (V) along with new state named "tri-domain state". The tri-domain state is observed in sufficiently large width of ring. The magnetic reversible mechanism and transition of states are explained with help of vector field display. The transitions from one state to other occur by propagation of domain wall. The vertical parts of hexagonal rings play important role in developing the new "tri-domain" state. The behaviors of switching fields from onion to tri-domain (HO-Tr), tri-domain to vortex state (HTr-V) and vortex to onion state and "states size" are discussed in term of geometrical parameter of ring.

  1. Students Losing Interest? How to Help them Adapt to Changes in the Classroom.

    ERIC Educational Resources Information Center

    Fawcett, Gay

    1999-01-01

    Discusses how reform affects students and how teachers can help them adapt to change. After explaining the principles of change and how they affect students, the paper examines the stages of change (comfortable dependence, anxiety, and comfortable independence); discusses students and the process of change; explains the supports that students need…

  2. Learning Science through the PDEODE Teaching Strategy: Helping Students Make Sense of Everyday Situations

    ERIC Educational Resources Information Center

    Costu, Bayram

    2008-01-01

    The aim of this study was to investigate effectiveness of PDEODE (Predict-Discuss-Explain-Observe-Discuss-Explain) teaching strategy in helping students make sense of everyday situations. For this, condensation concept was chosen among many science concepts since it is related to many everyday-life events. Forty-eight eleventh graders students…

  3. In silico evolution of biochemical networks

    NASA Astrophysics Data System (ADS)

    Francois, Paul

    2010-03-01

    We use computational evolution to select models of genetic networks that can be built from a predefined set of parts to achieve a certain behavior. Selection is made with the help of a fitness defining biological functions in a quantitative way. This fitness has to be specific to a process, but general enough to find processes common to many species. Computational evolution favors models that can be built by incremental improvements in fitness rather than via multiple neutral steps or transitions through less fit intermediates. With the help of these simulations, we propose a kinetic view of evolution, where networks are rapidly selected along a fitness gradient. This mathematics recapitulates Darwin's original insight that small changes in fitness can rapidly lead to the evolution of complex structures such as the eye, and explain the phenomenon of convergent/parallel evolution of similar structures in independent lineages. We will illustrate these ideas with networks implicated in embryonic development and patterning of vertebrates and primitive insects.

  4. The Fate of Exploding White Dwarfs

    NASA Astrophysics Data System (ADS)

    Fisher, Robert

    2018-01-01

    Type Ia supernovae play an important role as standardizable candles for cosmology, providing one of the most important probes into the nature of dark energy. Yet, the nature of the stellar progenitors which give rise to Type Ia supernovae remains elusive. For decades, the leading model explaining Type Ia supernovae properties consisted of a white dwarf accreting to near the Chandrasekhar mass, in the single-degenerate channel. More recently, a variety of lines of evidence point instead towards merging binary white dwarfs, in the double-degenerate channel, as the progenitors of most Type Ia supernovae. In this talk, I will focus upon recent advances at the interface between observation and theory which will help crack the Type Ia progenitor problem. In particular, I will present new insights obtained from recent multidimensional numerical simulations of both the double-degenerate and single-degenerate channels which I have undertaken with my students and collaborators. I will discuss how new models and observations will help elucidate the long-standing mystery of Type supernovae.

  5. Agent-based model of diffusion of N-acyl homoserine lactones in a multicellular environment of Pseudomonas aeruginosa and Candida albicans.

    PubMed

    Pérez-Rodríguez, Gael; Dias, Sónia; Pérez-Pérez, Martín; Fdez-Riverola, Florentino; Azevedo, Nuno F; Lourenço, Anália

    2018-03-08

    Experimental incapacity to track microbe-microbe interactions in structures like biofilms, and the complexity inherent to the mathematical modelling of those interactions, raises the need for feasible, alternative modelling approaches. This work proposes an agent-based representation of the diffusion of N-acyl homoserine lactones (AHL) in a multicellular environment formed by Pseudomonas aeruginosa and Candida albicans. Depending on the spatial location, C. albicans cells were variably exposed to AHLs, an observation that might help explain why phenotypic switching of individual cells in biofilms occurred at different time points. The simulation and algebraic results were similar for simpler scenarios, although some statistical differences could be observed (p < 0.05). The model was also successfully applied to a more complex scenario representing a small multicellular environment containing C. albicans and P. aeruginosa cells encased in a 3-D matrix. Further development of this model may help create a predictive tool to depict biofilm heterogeneity at the single-cell level.

  6. JASMINE simulator

    NASA Astrophysics Data System (ADS)

    Yamada, Yoshiyuki; Gouda, Naoteru; Yano, Taihei; Kobayashi, Yukiyasu; Tsujimoto, Takuji; Suganuma, Masahiro; Niwa, Yoshito; Sako, Nobutada; Hatsutori, Yoichi; Tanaka, Takashi

    2006-06-01

    We explain simulation tools in JASMINE project (JASMINE simulator). The JASMINE project stands at the stage where its basic design will be determined in a few years. Then it is very important to simulate the data stream generated by astrometric fields at JASMINE in order to support investigations into error budgets, sampling strategy, data compression, data analysis, scientific performances, etc. Of course, component simulations are needed, but total simulations which include all components from observation target to satellite system are also very important. We find that new software technologies, such as Object Oriented(OO) methodologies are ideal tools for the simulation system of JASMINE(the JASMINE simulator). In this article, we explain the framework of the JASMINE simulator.

  7. Developing a theory of the societal lifecycle of cigarette smoking : explaining and anticipating trends using information feedback.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brodsky, Nancy S.; Glass, Robert John, Jr.; Zagonel, Aldo A.

    Cigarette smoking presented the most significant public health challenge in the United States in the 20th Century and remains the single most preventable cause of morbidity and mortality in this country. A number of System Dynamics models exist that inform tobacco control policies. We reviewed them and discuss their contributions. We developed a theory of the societal lifecycle of smoking, using a parsimonious set of feedback loops to capture historical trends and explore future scenarios. Previous work did not explain the long-term historical patterns of smoking behaviors. Much of it used stock-and-flow to represent the decline in prevalence in themore » recent past. With noted exceptions, information feedbacks were not embedded in these models. We present and discuss our feedback-rich conceptual model and illustrate the results of a series of simulations. A formal analysis shows phenomena composed of different phases of behavior with specific dominant feedbacks associated with each phase. We discuss the implications of our society's current phase, and conclude with simulations of what-if scenarios. Because System Dynamics models must contain information feedback to be able to anticipate tipping points and to help identify policies that exploit leverage in a complex system, we expanded this body of work to provide an endogenous representation of the century-long societal lifecycle of smoking.« less

  8. Tuning of Terahertz Resonances of Pyridyl Benzamide Derivatives by Electronegative Atom Substitution

    NASA Astrophysics Data System (ADS)

    Dash, Jyotirmayee; Ray, Shaumik; Devi, Nirmala; Basutkar, Nitin; Gonnade, Rajesh G.; Ambade, Ashootosh V.; Pesala, Bala

    2018-05-01

    N-(pyridin-2-yl) benzamide (Ph2AP)-based organic molecules with prominent terahertz (THz) signatures (less than 5 THz) have been synthesized. The THz resonances are tuned by substituting the most electronegative atom, fluorine, at ortho (2F-Ph2AP), meta (3F-Ph2AP), and para (4F-Ph2AP) positions in a Ph2AP molecule. Substitution of fluorine helps in varying the charge distribution of the atoms forming hydrogen bond and hence strength of the hydrogen bond is varied which helps in tuning the THz resonances. The tuning of lower THz resonances of 2F-Ph2AP, 3F-Ph2AP, and 4F-Ph2AP has been explained in terms of compliance constant (relaxed force constant). Four-molecule cluster simulations have been carried out using Gaussian09 software to calculate the compliance constant of the hydrogen bonds. Crystal structure simulations of the above molecules using CRYSTAL14 software have been carried out to understand the origin of THz resonances. It has been observed that THz resonances are shifted to higher frequencies with stronger hydrogen bonds. The study shows that 3F-Ph2AP and 4F-Ph2AP have higher hydrogen bond strength and hence the THz resonances originating due to stretching of intermolecular hydrogen bonds have been shifted to higher frequencies compared to 2F-Ph2AP. The methodology presented here will help in designing novel organic molecules by substituting various electronegative atoms in order to achieve prominent THz resonances.

  9. Full particle simulations of quasi-perpendicular shocks

    NASA Astrophysics Data System (ADS)

    Lembège, B.

    This tutorial-style review is dedicated to the different strategies and constraints used for analysing the dynamics of a collisionless shocks with full particle simulations. Main results obtained with such simulations can be found in published materials (recent references are provided in this text); these will be only quoted herein in order to illustrate a few aspects of these simulations. Thanks to the large improvement of super computers, full particle simulations reveal to be quite helpful for analyzing in details the dynamics of collisionless shocks. The main characteristics of such codes can be shortly reminded as follows: one resolves the full set of Poisson and Maxwell's equations without any approximation. Two approaches are commonly used for resolving this equation's set, more precisely the space derivatives: (i) the finite difference approach and (ii) the use of FFT's (Fast Fourier Transform). Two advantages of approach (ii) are that FFT's are highly optimized in supercomputers libraries, and these allow to separate all fields components into two groups: the longitudinal electrostatic component El (solution of Poisson equation) and the transverse electromagnetic components Et and Bt solutions of the Maxwell's equations (so called "fields pusher"). Such a separation is quite helpful in the post processing stage necessary for the data analysis, as will be explained in the presentation. both ions and electrons populations are treated as individual finite-size particles and suffer the effects of all fields via the Lorentz force, so called "particle pusher", which is applied to each particle. Because of the large number of particles commonly used, the particle pusher represents the most expensive part of the calculations on which most efforts of optimisation needs to be performed (in terms of "vectorisation" or of "parallelism"). Relativistic effects may be included in this force via the use of particle momemtum. Each particle has three velocity components (vx, vy, vz), but may have 1, 2 or 3 space coordinates (x, y, z) according to the dimension of the code of concern.

  10. Modelling Cognitive Style in a Peer Help Network.

    ERIC Educational Resources Information Center

    Bull, Susan; McCalla, Gord

    2002-01-01

    Explains I-Help, a computer-based peer help network where students can ask and answer questions about assignments and courses based on the metaphor of a help desk. Highlights include cognitive style; user modeling in I-Help; matching helpers to helpees; and types of questions. (Contains 64 references.) (LRW)

  11. Decoding the Neoliberal Subjectivity in Self-Helping Adult Learners

    ERIC Educational Resources Information Center

    Lee, Moosung

    2017-01-01

    This article explores and explains the subjectivity of self-helping adult learners, as depicted in contemporary, best-selling self-help books. It interrogates how those self-help texts embody particular features of self-helping subjectivity by appropriating neoliberalist perspectives on self and the world. It illuminates four salient features of…

  12. Analogue modelling for localization of deformation in the extensional pull-apart basins: comparison with the west part of NAF, Turkey

    NASA Astrophysics Data System (ADS)

    Bulkan, Sibel; Storti, Fabrizio; Cavozzi, Cristian; Vannucchi, Paola

    2017-04-01

    Analogue modelling remains one of the best methods for investigating progressive deformation of pull apart systems in strike slip faults that are poorly known. Analogue model experiments for the North Anatolian Fault (NAF) system around the Sea of Marmara are extremely rare in the geological literature. Our purpose in this work is to monitor the relation between the horizontal propagation and branching of the strike slip fault, and the structural and topographic expression resulting from this process. These experiments may provide insights into the geometric evolution and kinematic of west part of the NAF system. For this purpose, we run several 3D sand box experiments, appropriately scaled. Plexiglass sheets were purposely cut to simulate the geometry of the NAF. Silicone was placed on the top of these to simulate the viscous lower crust, while the brittle upper crust was simulated with pure dry sand. Dextral relative fault motion was imposed as well using different velocities to reproduce different strain rates and pull apart formation at the releasing bend. Our experiments demonstrate the variation of the shear zone shapes and how the master-fault propagates during the deformation, helping to cover the gaps between geodetic and geologic slip information. Lower crustal flow may explain how the deformation is transferred to the upper crust, and stress partitioned among the strike slip faults and pull-apart basin systems. Stress field evolution seems to play an interesting role to help strain localization. We compare the results of these experiments with natural examples around the western part of NAF and with seismic observations.

  13. Silicon etch with chromium ions generated by a filtered or non-filtered cathodic arc discharge

    PubMed Central

    Scopece, Daniele; Döbeli, Max; Passerone, Daniele; Maeder, Xavier; Neels, Antonia; Widrig, Beno; Dommann, Alex; Müller, Ulrich; Ramm, Jürgen

    2016-01-01

    Abstract The pre-treatment of substrate surfaces prior to deposition is important for the adhesion of physical vapour deposition coatings. This work investigates Si surfaces after the bombardment by energetic Cr ions which are created in cathodic arc discharges. The effect of the pre-treatment is analysed by X-ray diffraction, Rutherford backscattering spectroscopy, scanning electron microscopy and in-depth X-ray photoemission spectroscopy and compared for Cr vapour produced from a filtered and non-filtered cathodic arc discharge. Cr coverage as a function of ion energy was also predicted by TRIDYN Monte Carlo calculations. Discrepancies between measured and simulated values in the transition regime between layer growth and surface removal can be explained by the chemical reactions between Cr ions and the Si substrate or between the substrate surface and the residual gases. Simulations help to find optimum and more stable parameters for specific film and substrate combinations faster than trial-and-error procedure. PMID:27877854

  14. In the Absence of Writhe, DNA Relieves Torsional Stress with Localized, Sequence-Dependent Structural Failure to Preserve B-form

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Randall, Graham L.; Zechiedrich, E. L.; Pettitt, Bernard M.

    2009-09-01

    To understand how underwinding and overwinding the DNA helix affects its structure, we simulated 19 independent DNA systems with fixed degrees of twist using molecular dynamics in a system that does not allow writhe. Underwinding DNA induced spontaneous, sequence-dependent base flipping and local denaturation, while overwinding DNA induced the formation of Pauling-like DNA (P-DNA). The winding resulted in a bimodal state simultaneously including local structural failure and B-form DNA for both underwinding and extreme overwinding. Our simulations suggest that base flipping and local denaturation may provide a landscape influencing protein recognition of DNA sequence to affect, for examples, replication, transcriptionmore » and recombination. Additionally, our findings help explain results from singlemolecule experiments and demonstrate that elastic rod models are strictly valid on average only for unstressed or overwound DNA up to P-DNA formation. Finally, our data support a model in which base flipping can result from torsional stress.« less

  15. Slow Cooling in Low Metallicity Clouds: An Origin of Globular Cluster Bimodality?

    NASA Astrophysics Data System (ADS)

    Fernandez, Ricardo; Bryan, Greg L.

    2018-05-01

    We explore the relative role of small-scale fragmentation and global collapse in low-metallicity clouds, pointing out that in such clouds the cooling time may be longer than the dynamical time, allowing the cloud to collapse globally before it can fragment. This, we suggest, may help to explain the formation of the low-metallicity globular cluster population, since such dense stellar systems need a large amount of gas to be collected in a small region (without significant feedback during the collapse). To explore this further, we carry out numerical simulations of low-metallicity Bonner-Ebert stable gas clouds, demonstrating that there exists a critical metallicity (between 0.001 and 0.01 Z⊙) below which the cloud collapses globally without fragmentation. We also run simulations including a background radiative heating source, showing that this can also produce clouds that do not fragment, and that the critical metallicity - which can exceed the no-radiation case - increases with the heating rate.

  16. Velocity mode transition of dynamic crack propagation in hyperviscoelastic materials: A continuum model study

    PubMed Central

    Kubo, Atsushi; Umeno, Yoshitaka

    2017-01-01

    Experiments of crack propagation in rubbers have shown that a discontinuous jump of crack propagation velocity can occur as energy release rate increases, which is known as the “mode transition” phenomenon. Although it is believed that the mode transition is strongly related to the mechanical properties, the nature of the mode transition had not been revealed. In this study, dynamic crack propagation on an elastomer was investigated using the finite element method (FEM) with a hyperviscoelastic material model. A series of pure shear test was carried out numerically with FEM simulations and crack velocities were measured under various values of tensile strain. As a result, our FEM simulations successfully reproduced the mode transition. The success of realising the mode transition phenomenon by a simple FEM model, which was achieved for the first time ever, helped to explain that the phenomenon occurs owing to a characteristic non-monotonic temporal development of principal stress near the crack tip. PMID:28186205

  17. Insights into the transmission of respiratory infectious diseases through empirical human contact networks

    PubMed Central

    Huang, Chunlin; Liu, Xingwu; Sun, Shiwei; Li, Shuai Cheng; Deng, Minghua; He, Guangxue; Zhang, Haicang; Wang, Chao; Zhou, Yang; Zhao, Yanlin; Bu, Dongbo

    2016-01-01

    In this study, we present representative human contact networks among Chinese college students. Unlike schools in the US, human contacts within Chinese colleges are extremely clustered, partly due to the highly organized lifestyle of Chinese college students. Simulations of influenza spreading across real contact networks are in good accordance with real influenza records; however, epidemic simulations across idealized scale-free or small-world networks show considerable overestimation of disease prevalence, thus challenging the widely-applied idealized human contact models in epidemiology. Furthermore, the special contact pattern within Chinese colleges results in disease spreading patterns distinct from those of the US schools. Remarkably, class cancelation, though simple, shows a mitigating power equal to quarantine/vaccination applied on ~25% of college students, which quantitatively explains its success in Chinese colleges during the SARS period. Our findings greatly facilitate reliable prediction of epidemic prevalence, and thus should help establishing effective strategies for respiratory infectious diseases control. PMID:27526868

  18. Ram Pressure Stripping of Galaxy JO201

    NASA Astrophysics Data System (ADS)

    Zhong, Greta; Tonnesen, Stephanie; Jaffé, Yara; Bellhouse, Callum; Bianca Poggianti

    2017-01-01

    Despite the discovery of the morphology-density relation more than 30 years ago, the process driving the evolution of spiral galaxies into S0s in clusters is still widely debated. Ram pressure stripping--the removal of a galaxy's interstellar medium by the pressure of the intracluster medium through which it orbits--may help explain galactic evolution and quenching in clusters. MUSE (Multi Unit Spectroscopic Explorer) observational data of galaxy JO201 in cluster Abell 85 reveal it to be a jellyfish galaxy--one with an H-alpha emitting gas tail on only one side. We model the possible orbits for this galaxy, constrained by the cluster mass profile, line of sight velocity, and projected distance from the cluster center. Using Enzo, an adaptive mesh refinement hydrodynamics code, we simulate effects of ram pressure on this galaxy for a range of possible orbits. We present comparisons of both the morphology and velocity structure of our simulated galaxy to the observations of H-alpha emission.

  19. Velocity mode transition of dynamic crack propagation in hyperviscoelastic materials: A continuum model study

    NASA Astrophysics Data System (ADS)

    Kubo, Atsushi; Umeno, Yoshitaka

    2017-02-01

    Experiments of crack propagation in rubbers have shown that a discontinuous jump of crack propagation velocity can occur as energy release rate increases, which is known as the “mode transition” phenomenon. Although it is believed that the mode transition is strongly related to the mechanical properties, the nature of the mode transition had not been revealed. In this study, dynamic crack propagation on an elastomer was investigated using the finite element method (FEM) with a hyperviscoelastic material model. A series of pure shear test was carried out numerically with FEM simulations and crack velocities were measured under various values of tensile strain. As a result, our FEM simulations successfully reproduced the mode transition. The success of realising the mode transition phenomenon by a simple FEM model, which was achieved for the first time ever, helped to explain that the phenomenon occurs owing to a characteristic non-monotonic temporal development of principal stress near the crack tip.

  20. Velocity mode transition of dynamic crack propagation in hyperviscoelastic materials: A continuum model study.

    PubMed

    Kubo, Atsushi; Umeno, Yoshitaka

    2017-02-10

    Experiments of crack propagation in rubbers have shown that a discontinuous jump of crack propagation velocity can occur as energy release rate increases, which is known as the "mode transition" phenomenon. Although it is believed that the mode transition is strongly related to the mechanical properties, the nature of the mode transition had not been revealed. In this study, dynamic crack propagation on an elastomer was investigated using the finite element method (FEM) with a hyperviscoelastic material model. A series of pure shear test was carried out numerically with FEM simulations and crack velocities were measured under various values of tensile strain. As a result, our FEM simulations successfully reproduced the mode transition. The success of realising the mode transition phenomenon by a simple FEM model, which was achieved for the first time ever, helped to explain that the phenomenon occurs owing to a characteristic non-monotonic temporal development of principal stress near the crack tip.

  1. Liquid-Gas-Like Phase Transition in Sand Flow Under Microgravity

    NASA Astrophysics Data System (ADS)

    Huang, Yu; Zhu, Chongqiang; Xiang, Xiang; Mao, Wuwei

    2015-06-01

    In previous studies of granular flow, it has been found that gravity plays a compacting role, causing convection and stratification by density. However, there is a lack of research and analysis of the characteristics of different particles' motion under normal gravity contrary to microgravity. In this paper, we conduct model experiments on sand flow using a model test system based on a drop tower under microgravity, within which the characteristics and development processes of granular flow under microgravity are captured by high-speed cameras. The configurations of granular flow are simulated using a modified MPS (moving particle simulation), which is a mesh-free, pure Lagrangian method. Moreover, liquid-gas-like phase transitions in the sand flow under microgravity, including the transitions to "escaped", "jumping", and "scattered" particles are highlighted, and their effects on the weakening of shear resistance, enhancement of fluidization, and changes in particle-wall and particle-particle contact mode are analyzed. This study could help explain the surface geology evolution of small solar bodies and elucidate the nature of granular interaction.

  2. Distinct mechanisms explain the control of reach speed planning: evidence from a race model framework.

    PubMed

    Venkataratamani, Prasanna Venkhatesh; Murthy, Aditya

    2018-05-16

    Previous studies have investigated the computational architecture underlying the voluntary control of reach movements that demands a change in position or direction of movement planning. Here we used a novel task, where subjects either had to increase or decrease the movement speed according to a change in target color that occurred randomly during a trial. The applicability of different race models to such a speed redirect task was assessed. We found that the predictions of an independent race model that instantiated an abort and re-plan strategy was consistent with all aspects of performance in the fast to slow speed condition. The results from modeling indicated a peculiar asymmetry, in that while the fast to slow speed change required inhibition, none of the standard race models were able to explain how movements changed from slow to fast speeds. Interestingly, a weighted averaging model that simulated the gradual merge of two kinematic plans explained behavior in the slow to fast speed task. In summary, our work shows how a race model framework can provide an understanding of how the brain controls of different aspects of reach movement planning and help distinguish between an abort and re-plan strategy from merging of plans.

  3. All-atom simulations and free-energy calculations of coiled-coil peptides with lipid bilayers: binding strength, structural transition, and effect on lipid dynamics

    NASA Astrophysics Data System (ADS)

    Woo, Sun Young; Lee, Hwankyu

    2016-03-01

    Peptides E and K, which are synthetic coiled-coil peptides for membrane fusion, were simulated with lipid bilayers composed of lipids and cholesterols at different ratios using all-atom models. We first calculated free energies of binding from umbrella sampling simulations, showing that both E and K peptides tend to adsorb onto the bilayer surface, which occurs more strongly in the bilayer composed of smaller lipid headgroups. Then, unrestrained simulations show that K peptides more deeply insert into the bilayer with partially retaining the helical structure, while E peptides less insert and predominantly become random coils, indicating the structural transition from helices to random coils, in quantitative agreement with experiments. This is because K peptides electrostatically interact with lipid phosphates, as well as because hydrocarbons of lysines of K peptide are longer than those of glutamic acids of E peptide and thus form stronger hydrophobic interactions with lipid tails. This deeper insertion of K peptide increases the bilayer dynamics and a vacancy below the peptide, leading to the rearrangement of smaller lipids. These findings help explain the experimentally observed or proposed differences in the insertion depth, binding strength, and structural transition of E and K peptides, and support the snorkeling effect.

  4. All-atom simulations and free-energy calculations of coiled-coil peptides with lipid bilayers: binding strength, structural transition, and effect on lipid dynamics.

    PubMed

    Woo, Sun Young; Lee, Hwankyu

    2016-03-01

    Peptides E and K, which are synthetic coiled-coil peptides for membrane fusion, were simulated with lipid bilayers composed of lipids and cholesterols at different ratios using all-atom models. We first calculated free energies of binding from umbrella sampling simulations, showing that both E and K peptides tend to adsorb onto the bilayer surface, which occurs more strongly in the bilayer composed of smaller lipid headgroups. Then, unrestrained simulations show that K peptides more deeply insert into the bilayer with partially retaining the helical structure, while E peptides less insert and predominantly become random coils, indicating the structural transition from helices to random coils, in quantitative agreement with experiments. This is because K peptides electrostatically interact with lipid phosphates, as well as because hydrocarbons of lysines of K peptide are longer than those of glutamic acids of E peptide and thus form stronger hydrophobic interactions with lipid tails. This deeper insertion of K peptide increases the bilayer dynamics and a vacancy below the peptide, leading to the rearrangement of smaller lipids. These findings help explain the experimentally observed or proposed differences in the insertion depth, binding strength, and structural transition of E and K peptides, and support the snorkeling effect.

  5. Understanding the Role of Chaos Theory in Military Decision Making

    DTIC Science & Technology

    2009-01-01

    Because chaos is bounded, planners can create allowances for system noise. The existence of strange and normal chaotic attractors helps explain why... strange and normal chaotic attractors helps explain why system turbulence is uneven or concentrated around specific solution regions. Finally, the...give better understanding of the implications of chaos: sensitivity to initial conditions, strange attractors , and constants of motion. By showing the

  6. Understanding the Central Equatorial African long-term drought using AMIP-type simulations

    NASA Astrophysics Data System (ADS)

    Hua, Wenjian; Zhou, Liming; Chen, Haishan; Nicholson, Sharon E.; Jiang, Yan; Raghavendra, Ajay

    2018-02-01

    Previous studies show that Indo-Pacific sea surface temperature (SST) variations may help to explain the observed long-term drought during April-May-June (AMJ) since the 1990s over Central equatorial Africa (CEA). However, the underlying physical mechanisms for this drought are still not clear due to observation limitations. Here we use the AMIP-type simulations with 24 ensemble members forced by observed SSTs from the ECHAM4.5 model to explore the likely physical processes that determine the rainfall variations over CEA. We not only examine the ensemble mean (EM), but also compare the "good" and "poor" ensemble members to understand the intra-ensemble variability. In general, EM and the "good" ensemble member can simulate the drought and associated reduced vertical velocity and anomalous anti-cyclonic circulation in the lower troposphere. However, the "poor" ensemble members cannot simulate the drought and associated circulation patterns. These contrasts indicate that the drought is tightly associated with the tropical Walker circulation and atmospheric teleconnection patterns. If the observational circulation patterns cannot be reproduced, the CEA drought will not be captured. Despite the large intra-ensemble spread, the model simulations indicate an essential role of SST forcing in causing the drought. These results suggest that the long-term drought may result from tropical Indo-Pacific SST variations associated with the enhanced and westward extended tropical Walker circulation.

  7. NASA Missions Have Their Eyes Peeled on Pluto Artist Concept

    NASA Image and Video Library

    2015-07-09

    This artist concept shows NASA fleet of observatories busily gathering data before and after July 14, 2015 to help piece together what we know about Pluto, and what features New Horizons data might help explain. What's icy, has "wobbly" potato-shaped moons, and is arguably the world's favorite dwarf planet? The answer is Pluto, and NASA's New Horizons is speeding towards the edge of our solar system for a July 14 flyby. It won't be making observations alone; NASA's fleet of observatories will be busy gathering data before and after to help piece together what we know about Pluto, and what features New Horizons data might help explain. http://photojournal.jpl.nasa.gov/catalog/PIA19703

  8. Large and small-scale structures and the dust energy balance problem in spiral galaxies

    NASA Astrophysics Data System (ADS)

    Saftly, W.; Baes, M.; De Geyter, G.; Camps, P.; Renaud, F.; Guedes, J.; De Looze, I.

    2015-04-01

    The interstellar dust content in galaxies can be traced in extinction at optical wavelengths, or in emission in the far-infrared. Several studies have found that radiative transfer models that successfully explain the optical extinction in edge-on spiral galaxies generally underestimate the observed FIR/submm fluxes by a factor of about three. In order to investigate this so-called dust energy balance problem, we use two Milky Way-like galaxies produced by high-resolution hydrodynamical simulations. We create mock optical edge-on views of these simulated galaxies (using the radiative transfer code SKIRT), and we then fit the parameters of a basic spiral galaxy model to these images (using the fitting code FitSKIRT). The basic model includes smooth axisymmetric distributions along a Sérsic bulge and exponential disc for the stars, and a second exponential disc for the dust. We find that the dust mass recovered by the fitted models is about three times smaller than the known dust mass of the hydrodynamical input models. This factor is in agreement with previous energy balance studies of real edge-on spiral galaxies. On the other hand, fitting the same basic model to less complex input models (e.g. a smooth exponential disc with a spiral perturbation or with random clumps), does recover the dust mass of the input model almost perfectly. Thus it seems that the complex asymmetries and the inhomogeneous structure of real and hydrodynamically simulated galaxies are a lot more efficient at hiding dust than the rather contrived geometries in typical quasi-analytical models. This effect may help explain the discrepancy between the dust emission predicted by radiative transfer models and the observed emission in energy balance studies for edge-on spiral galaxies.

  9. Protoplanetary Disks and Planet Formation a Computational Perspective

    NASA Astrophysics Data System (ADS)

    Backus, Isaac

    In this thesis I present my research on the early stages of planet formation. Using advanced computational modeling techniques, I study global gas and gravitational dynamics in proto- planetary disks (PPDs) on length scales from the radius of Jupiter to the size of the solar system. In that environment, I investigate the formation of gas giants and the migration, enhancement, and distribution of small solids--the precursors to planetesimals and gas giant cores. I examine numerical techniques used in planet formation and PPD modeling, especially methods for generating initial conditions (ICs) in these unstable, chaotic systems. Disk simulation outcomes may depend strongly on ICs, which may explain results in the literature. I present the largest suite of high resolution PPD simulations to-date and argue that direct fragmentations of PPDs around M-Dwarfs is a plausible path to rapidly forming gas giants. I implement dust physics to track the migration of centimeter and smaller dust grains in very high resolution PPD simulations. While current dust methods are slow, with strict resolution and/or time-stepping requirements, and have some serious numerical issues, we can still demonstrate that dust does not concentrate at the pressure maxima of spiral arms, an indication that spiral features observed in the dust component are at least as well resolved in the gas. Additionally, coherent spiral arms do not limit dust settling. We suggest a novel mechanism for disk fragmentation at large radii driven by dust accretion from the surrounding nebula. We also investigate self induced dust traps, a mechanism which may help explain the growth of solids beyond meter sizes. We argue that current apparent demonstrations of this mechanism may be due to numerical artifacts and require further investigation.

  10. Theory of Planned Behavior including self-stigma and perceived barriers explain help-seeking behavior for sexual problems in Iranian women suffering from epilepsy.

    PubMed

    Lin, Chung-Ying; Oveisi, Sonia; Burri, Andrea; Pakpour, Amir H

    2017-03-01

    To apply the Theory of Planned Behavior (TPB) and the two additional concepts self-stigma and perceived barriers to the help-seeking behavior for sexual problems in women with epilepsy. In this 18-month follow-up study, TPB elements, including attitude, subjective norm, perceived behavioral control, and behavioral intention along with self-stigma and perceived barriers in seeking help for sexual problems were assessed in n=818 women with epilepsy (94.0% aged ≤40years). The basic TPB model (model 1) and the TPB model additionally including self-stigma and perceived barriers (Model 2) were analyzed using structural equation modeling (SEM). Both SEM models showed satisfactory model fits. According to model, attitude, subjective norms, perceived behavioral control, and intention explained 63.1% of the variance in help-seeking behavior. Variance was slightly higher (64.5%) when including self-stigma and perceived barriers (model 2). In addition, the fit indices of the models were better highlighting the importance of self-stigma and perceived barriers in help-seeking behavior for sexual problems. Theory of Planned Behavior is useful in explaining help-seeking behavior for sexual problems in women with epilepsy. Self-stigma and perceived barriers are additional factors that should be considered in future interventions aiming to adopt TPB to improve help-seeking behavior for sexual problems. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Going Online: Helping Technical Communicators Help Translators.

    ERIC Educational Resources Information Center

    Flint, Patricia; Lord van Slyke, Melanie; Starke-Meyerring, Doreen; Thompson, Aimee

    1999-01-01

    Explains why technical communicators should help translators. Offers tips for creating "translation-friendly" documentation. Describes the research and design process used by the authors to create an online tutorial that provides technical communicators at a medical technology company the information they need to help them write and…

  12. Molecular understanding of osmosis in semipermeable membranes.

    PubMed

    Raghunathan, A V; Aluru, N R

    2006-07-14

    We investigate single-file osmosis of water through a semipermeable membrane with an uncharged, a positively and a negatively charged nanopore. Molecular dynamics simulations indicate that the osmotic flux through a negatively charged pore (J_) is higher compared to the osmotic flux in a positively charged pore (J+) followed by the osmotic flux in the uncharged pore (J(0)), i.e., J_ > J+ > J(0). The molecular mechanisms governing osmosis, steady state osmosis, and the observed osmotic flux dependence on the nanopore charge are explained by computing all the molecular interactions involved and identifying the molecular interactions that play an important role during and after osmosis. This study helps in a fundamental understanding of osmosis and in the design of advanced nanoporous membranes for various applications of osmosis.

  13. Dielectric Sensors Based on Electromagnetic Energy Tunneling

    PubMed Central

    Siddiqui, Omar; Kashanianfard, Mani; Ramahi, Omar

    2015-01-01

    We show that metallic wires embedded in narrow waveguide bends and channels demonstrate resonance behavior at specific frequencies. The electromagnetic energy at these resonances tunnels through the narrow waveguide channels with almost no propagation losses. Under the tunneling behavior, high-intensity electromagnetic fields are produced in the vicinity of the metallic wires. These intense field resonances can be exploited to build highly sensitive dielectric sensors. The sensor operation is explained with the help of full-wave simulations. A practical setup consisting of a 3D waveguide bend is presented to experimentally observe the tunneling phenomenon. The tunneling frequency is predicted by determining the input impedance minima through a variational formula based on the Green function of a probe-excited parallel plate waveguide. PMID:25835188

  14. Collisionless reconnection in a quasi-neutral sheet near marginal stability

    NASA Technical Reports Server (NTRS)

    Pritchett, P. L.; Coroniti, F. V.; Pellat, R.; Karimabadi, H.

    1989-01-01

    Particle simulations are used to investigate the process of collisionless reconnection in a magnetotail configuration which includes a pressure gradient along the tail axis and tail flaring. In the absence of electron stabilization effects, the tearing mode is stabilized when the ion gyrofrequency in the normal field exceeds the growth rate in the corresponding one-dimensional current sheet. The presence of a low-frequency electromagnetic perturbation in the lobes can serve to destabilize a marginally stable current sheet by producing an extended neutral-sheet region which can then undergo reconnection. These results help to explain how X-type neutral lines, such as those associated with the onset of magnetospheric substorms, can be formed in the near-earth plasma sheet.

  15. Diary of a Wimpy Cycle

    NASA Technical Reports Server (NTRS)

    Hathaway, David; Upton, Lisa

    2013-01-01

    The cause of the low and extended minimum in solar activity between Sunspot Cycles 23 and 24 was the small size of Sunspot Cycle 24 itself - small cycles start late and leave behind low minima. Cycle 24 is small because the polar fields produced during Cycle 23 were substantially weaker than those produced during the previous cycles and those (weak) polar fields are the seeds for the activity of the following cycle. Here we discuss the observed characteristics of Cycle 24 and contrast them to the characteristics of previous cycles. We present observations and Magnetic Flux Transport simulations with data assimilated from SOHO/MDI and SDO/HMI that help to explain these differences and point the way to predictions of future activity levels.

  16. Kinship, parental manipulation and evolutionary origins of eusociality.

    PubMed

    Kapheim, Karen M; Nonacs, Peter; Smith, Adam R; Wayne, Robert K; Wcislo, William T

    2015-03-22

    One of the hallmarks of eusociality is that workers forego their own reproduction to assist their mother in raising siblings. This seemingly altruistic behaviour may benefit workers if gains in indirect fitness from rearing siblings outweigh the loss of direct fitness. If worker presence is advantageous to mothers, however, eusociality may evolve without net benefits to workers. Indirect fitness benefits are often cited as evidence for the importance of inclusive fitness in eusociality, but have rarely been measured in natural populations. We compared inclusive fitness of alternative social strategies in the tropical sweat bee, Megalopta genalis, for which eusociality is optional. Our results show that workers have significantly lower inclusive fitness than females that found their own nests. In mathematical simulations based on M. genalis field data, eusociality cannot evolve with reduced intra-nest relatedness. The simulated distribution of alternative social strategies matched observed distributions of M. genalis social strategies when helping behaviour was simulated as the result of maternal manipulation, but not as worker altruism. Thus, eusociality in M. genalis is best explained through kin selection, but the underlying mechanism is likely maternal manipulation. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  17. Simulating CRN derived erosion rates in a transient Andean catchment using the TTLEM model

    NASA Astrophysics Data System (ADS)

    Campforts, Benjamin; Vanacker, Veerle; Herman, Frédéric; Schwanghart, Wolfgang; Tenrorio Poma, Gustavo; Govers, Gerard

    2017-04-01

    Assessing the impact of mountain building and erosion on the earth surface is key to reconstruct and predict terrestrial landscape evolution. Landscape evolution models (LEMs) are an essential tool in this research effort as they allow to integrate our growing understanding of physical processes governing erosion and transport of mass across the surface. The recent development of several LEMs opens up new areas of research in landscape evolution. Here, we want to seize this opportunity by answering a fundamental research question: does a model designed to simulate landscape evolution over geological timescales allows to simulate spatially varying erosion rates at a millennial timescale? We selected the highly transient Paute catchment in the Southeastern Ecuadorian Andes as a study area. We found that our model (TTLEM) is capable to better explain the spatial patterns of ca. 30 Cosmogenic Radio Nuclide (CRN) derived catchment wide erosion rates in comparison to a classical, statistical approach. Thus, the use of process-based landscape evolution models may not only be of great help to understand long-term landscape evolution but also in understanding spatial and temporal variations in sediment fluxes at the millennial time scale.

  18. Influence of large-scale zonal flows on the evolution of stellar and planetary magnetic fields

    NASA Astrophysics Data System (ADS)

    Petitdemange, Ludovic; Schrinner, Martin; Dormy, Emmanuel; ENS Collaboration

    2011-10-01

    Zonal flows and magnetic field are present in various objects as accretion discs, stars and planets. Observations show a huge variety of stellar and planetary magnetic fields. Of particular interest is the understanding of cyclic field variations, as known from the sun. They are often explained by an important Ω-effect, i.e., by the stretching of field lines because of strong differential rotation. We computed the dynamo coefficients for an oscillatory dynamo model with the help of the test-field method. We argue that this model is of α2 Ω -type and here the Ω-effect alone is not responsible for its cyclic time variation. More general conditions which lead to dynamo waves in global direct numerical simulations are presented. Zonal flows driven by convection in planetary interiors may lead to secondary instabilities. We showed that a simple, modified version of the MagnetoRotational Instability, i.e., the MS-MRI can develop in planteray interiors. The weak shear yields an instability by its constructive interaction with the much larger rotation rate of planets. We present results from 3D simulations and show that 3D MS-MRI modes can generate wave pattern at the surface of the spherical numerical domain. Zonal flows and magnetic field are present in various objects as accretion discs, stars and planets. Observations show a huge variety of stellar and planetary magnetic fields. Of particular interest is the understanding of cyclic field variations, as known from the sun. They are often explained by an important Ω-effect, i.e., by the stretching of field lines because of strong differential rotation. We computed the dynamo coefficients for an oscillatory dynamo model with the help of the test-field method. We argue that this model is of α2 Ω -type and here the Ω-effect alone is not responsible for its cyclic time variation. More general conditions which lead to dynamo waves in global direct numerical simulations are presented. Zonal flows driven by convection in planetary interiors may lead to secondary instabilities. We showed that a simple, modified version of the MagnetoRotational Instability, i.e., the MS-MRI can develop in planteray interiors. The weak shear yields an instability by its constructive interaction with the much larger rotation rate of planets. We present results from 3D simulations and show that 3D MS-MRI modes can generate wave pattern at the surface of the spherical numerical domain. The first author thanks DFG and PlanetMag project for financial support.

  19. High Selection Pressure Promotes Increase in Cumulative Adaptive Culture

    PubMed Central

    Vegvari, Carolin; Foley, Robert A.

    2014-01-01

    The evolution of cumulative adaptive culture has received widespread interest in recent years, especially the factors promoting its occurrence. Current evolutionary models suggest that an increase in population size may lead to an increase in cultural complexity via a higher rate of cultural transmission and innovation. However, relatively little attention has been paid to the role of natural selection in the evolution of cultural complexity. Here we use an agent-based simulation model to demonstrate that high selection pressure in the form of resource pressure promotes the accumulation of adaptive culture in spite of small population sizes and high innovation costs. We argue that the interaction of demography and selection is important, and that neither can be considered in isolation. We predict that an increase in cultural complexity is most likely to occur under conditions of population pressure relative to resource availability. Our model may help to explain why culture change can occur without major environmental change. We suggest that understanding the interaction between shifting selective pressures and demography is essential for explaining the evolution of cultural complexity. PMID:24489724

  20. Multilevel processes and cultural adaptation: Examples from past and present small-scale societies.

    PubMed

    Reyes-García, V; Balbo, A L; Gomez-Baggethun, E; Gueze, M; Mesoudi, A; Richerson, P; Rubio-Campillo, X; Ruiz-Mallén, I; Shennan, S

    2016-12-01

    Cultural adaptation has become central in the context of accelerated global change with authors increasingly acknowledging the importance of understanding multilevel processes that operate as adaptation takes place. We explore the importance of multilevel processes in explaining cultural adaptation by describing how processes leading to cultural (mis)adaptation are linked through a complex nested hierarchy, where the lower levels combine into new units with new organizations, functions, and emergent properties or collective behaviours. After a brief review of the concept of "cultural adaptation" from the perspective of cultural evolutionary theory and resilience theory, the core of the paper is constructed around the exploration of multilevel processes occurring at the temporal, spatial, social and political scales. We do so by examining small-scale societies' case studies. In each section, we discuss the importance of the selected scale for understanding cultural adaptation and then present an example that illustrates how multilevel processes in the selected scale help explain observed patterns in the cultural adaptive process. We end the paper discussing the potential of modelling and computer simulation for studying multilevel processes in cultural adaptation.

  1. Information spreading in complex networks with participation of independent spreaders

    NASA Astrophysics Data System (ADS)

    Ma, Kun; Li, Weihua; Guo, Quantong; Zheng, Xiaoqi; Zheng, Zhiming; Gao, Chao; Tang, Shaoting

    2018-02-01

    Information diffusion dynamics in complex networks is often modeled as a contagion process among neighbors which is analogous to epidemic diffusion. The attention of previous literature is mainly focused on epidemic diffusion within one network, which, however neglects the possible interactions between nodes beyond the underlying network. The disease can be transmitted to other nodes by other means without following the links in the focal network. Here we account for this phenomenon by introducing the independent spreaders in a susceptible-infectious-recovered contagion process. We derive the critical epidemic thresholds on Erdős-Rényi and scale-free networks as a function of infectious rate, recovery rate and the activeness of independent spreaders. We also present simulation results on ER and SF networks, as well as on a real-world email network. The result shows that the extent to which a disease can infect might be more far-reaching, than we can explain in terms of link contagion only. Besides, these results also help to explain how activeness of independent spreaders can affect the diffusion process, which can be used to explore many other dynamical processes.

  2. Multilevel processes and cultural adaptation: Examples from past and present small-scale societies

    PubMed Central

    Reyes-García, V.; Balbo, A. L.; Gomez-Baggethun, E.; Gueze, M.; Mesoudi, A.; Richerson, P.; Rubio-Campillo, X.; Ruiz-Mallén, I.; Shennan, S.

    2016-01-01

    Cultural adaptation has become central in the context of accelerated global change with authors increasingly acknowledging the importance of understanding multilevel processes that operate as adaptation takes place. We explore the importance of multilevel processes in explaining cultural adaptation by describing how processes leading to cultural (mis)adaptation are linked through a complex nested hierarchy, where the lower levels combine into new units with new organizations, functions, and emergent properties or collective behaviours. After a brief review of the concept of “cultural adaptation” from the perspective of cultural evolutionary theory and resilience theory, the core of the paper is constructed around the exploration of multilevel processes occurring at the temporal, spatial, social and political scales. We do so by examining small-scale societies’ case studies. In each section, we discuss the importance of the selected scale for understanding cultural adaptation and then present an example that illustrates how multilevel processes in the selected scale help explain observed patterns in the cultural adaptive process. We end the paper discussing the potential of modelling and computer simulation for studying multilevel processes in cultural adaptation. PMID:27774109

  3. Shedding light on the different behavior of ionic and nonionic surfactants in emulsion polymerization: from atomistic simulations to experimental observations.

    PubMed

    Magi Meconi, Giulia; Ballard, Nicholas; Asua, José M; Zangi, Ronen

    2017-12-06

    Although surfactants are known to play a vital role in polymerization reactions carried out in dispersed media, many aspects of their use are poorly understood, perhaps none more so than the vastly different action of ionic and nonionic surfactants in emulsion polymerization. In this work, we combine experimental measurements of emulsion polymerization of styrene with atomistic molecular dynamics simulations to better understand the behavior of surfactants at monomer/polymer-water interfaces. In a batch emulsion polymerization of styrene, the nonionic surfactant Disponil AFX 1080 leads to two nucleation periods, in contrast to the behavior observed for the ionic surfactant SDS. This can be explained by the absorption of the nonionic surfactant into the organic phase at the early stages of the polymerization reaction which is then released as the reaction progresses. Indeed, we find that the partition coefficient of the surfactant between the organic phase and water increases with the amount of monomer in the former, and preferential partitioning is detected to organic phases containing at least 55% styrene. Results from molecular dynamics simulations confirm that spontaneous dissolution of the non-ionic surfactant into a styrene-rich organic phase occurs above a critical concentration of the surfactant adsorbed at the interface. Above this critical concentration, a linear correlation between the amount of surfactant adsorbed at the interface and that absorbed inside the organic phase is observed. To facilitate this absorption into a completely hydrophobic medium, water molecules accompany the intruding surfactants. Similar simulations but with the ionic surfactant instead did not result in any absorption of the surfactant into a neat styrene phase, likely because of its strongly hydrophilic head group. The unusual partitioning behavior of nonionic surfactants explains a number of observable features of emulsion polymerization reactions which use nonionic surfactants and should help with future development of processes for improved control over polymerization.

  4. Simulations Help School Leaders Hone People Skills: Simulations Help School Leaders Practice "Tough Conversations"

    ERIC Educational Resources Information Center

    Sparks, Sarah D.

    2011-01-01

    This article reports on a simulation training program for school leaders at Syracuse University. The project is creating a series of parent, teacher, student, and community-member roles to help principals and teachers learn how to handle tricky conversations. Supported by a three-year grant from the U.S. Department of Education's Institute of…

  5. Factors influencing intention to help and helping behaviour in witnesses of bullying in nursing settings.

    PubMed

    Báez-León, Carmen; Moreno-Jiménez, Bernardo; Aguirre-Camacho, Aldo; Olmos, Ricardo

    2016-12-01

    The role played by witnesses of bullying in nursing settings remains little studied, despite their potential relevance in explaining the onset and development of bullying. The objective of this study was to develop a model to account for witnesses' intention to help and helping behaviour in response to bullying in a nursing setting. Three hundred and thirty-seven witnesses completed self-report measures of variables predicting intention to help and helping behaviour. A full structural model was constructed using structural equation modelling. The intention to help victims was elicited by tension, group identity, support to peers' initiative to intervene and absence of fear of retaliation. However, engagement in helping behaviour was only predicted by the absence of fear of retaliation. This study shows that witnesses of bullying in nursing settings do not remain impassive, but their experienced discomfort and intention to help victims is not sufficient to predict helping behaviour. Fear of possible retaliation if intervening in favour of victims constitutes a crucial factor explaining witnesses' hesitation to help victims. Several implications for the implementation of policies directed at eradicating bullying in nursing settings are discussed. © 2016 John Wiley & Sons Ltd.

  6. The Differential role of parenting, peers, and temperament for explaining interindividual differences in 18-months-olds' comforting and helping.

    PubMed

    Schuhmacher, Nils; Collard, Jenny; Kärtner, Joscha

    2017-02-01

    This study analyzes temperamental and social correlates of 18-month-olds' (N=58) instrumental helping (i.e., handing over out-of-reach objects) and comforting (i.e., alleviating experimenter's distress). While out-of-reach helping as a basic type of prosocial behavior was not associated with any of the social and temperamental variables, comforting was associated with maternal responsible parenting, day care attendance, and temperamental fear, accounting for 34% of the total variance in a corresponding regression model. The data of the present study suggest that, while simple instrumental helping seems to be a robust developmental phenomenon, comforting is associated with specific social experiences and child temperament that constitute interindividual differences and thereby help to explain the domain-specific development of prosociality. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. The role of ecosystem-atmosphere interactions in simulated Amazonian precipitation decrease and forest dieback under global climate warming

    NASA Astrophysics Data System (ADS)

    Betts, R. A.; Cox, P. M.; Collins, M.; Harris, P. P.; Huntingford, C.; Jones, C. D.

    A suite of simulations with the HadCM3LC coupled climate-carbon cycle model is used to examine the various forcings and feedbacks involved in the simulated precipitation decrease and forest dieback. Rising atmospheric CO2 is found to contribute 20% to the precipitation reduction through the physiological forcing of stomatal closure, with 80% of the reduction being seen when stomatal closure was excluded and only radiative forcing by CO2 was included. The forest dieback exerts two positive feedbacks on the precipitation reduction; a biogeophysical feedback through reduced forest cover suppressing local evaporative water recycling, and a biogeochemical feedback through the release of CO2 contributing to an accelerated global warming. The precipitation reduction is enhanced by 20% by the biogeophysical feedback, and 5% by the carbon cycle feedback from the forest dieback. This analysis helps to explain why the Amazonian precipitation reduction simulated by HadCM3LC is more extreme than that simulated in other GCMs; in the fully-coupled, climate-carbon cycle simulation, approximately half of the precipitation reduction in Amazonia is attributable to a combination of physiological forcing and biogeophysical and global carbon cycle feedbacks, which are generally not included in other GCM simulations of future climate change. The analysis also demonstrates the potential contribution of regional-scale climate and ecosystem change to uncertainties in global CO2 and climate change projections. Moreover, the importance of feedbacks suggests that a human-induced increase in forest vulnerability to climate change may have implications for regional and global scale climate sensitivity.

  8. Helping Children Be Successful in Math: A Parent's Guide

    ERIC Educational Resources Information Center

    Online Submission, 2008

    2008-01-01

    Family involvement in children's math education is critical to helping kids succeed. "Helping Children Be Successful in Math" explains why--and how. (Contains 5 endnotes.) [Abstract modified to meet ERIC guidelines. This document was produced by DreamBox Learning, Inc.

  9. Could Trends in Time Children Spend with Parents Help Explain the Black-White Gap in Human Capital? Evidence from the American Time Use Survey

    ERIC Educational Resources Information Center

    Patterson, Richard W.

    2017-01-01

    It is widely believed that the time children spend with parents significantly impacts human capital formation. If time varies significantly between black and white children, this may help explain the large racial gap in test scores and wages. In this study, I use data from the American Time Use Survey to examine the patterns in the time black and…

  10. Dynamics of receptor-operated Ca(2+) currents through TRPC channels controlled via the PI(4,5)P2-PLC signaling pathway.

    PubMed

    Mori, Masayuki X; Itsuki, Kyohei; Hase, Hideharu; Sawamura, Seishiro; Kurokawa, Tatsuki; Mori, Yasuo; Inoue, Ryuji

    2015-01-01

    Transient receptor potential canonical (TRPC) channels are Ca(2+)-permeable, nonselective cation channels that carry receptor-operated Ca(2+) currents (ROCs) triggered by receptor-induced, phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2]. Within the vasculature, TRPC channel ROCs contribute to smooth muscle cell depolarization, vasoconstriction, and vascular remodeling. However, TRPC channel ROCs exhibit a variable response to receptor-stimulation, and the regulatory mechanisms governing TRPC channel activity remain obscure. The variability of ROCs may be explained by their complex regulation by PI(4,5)P2 and its metabolites, which differentially affect TRPC channel activity. To resolve the complex regulation of ROCs, the use of voltage-sensing phosphoinositide phosphatases and model simulation have helped to reveal the time-dependent contribution of PI(4,5)P2 and the possible role of PI(4,5)P2 in the regulation of ROCs. These approaches may provide unprecedented insight into the dynamics of PI(4,5)P2 regulation of TRPC channels and the fundamental mechanisms underlying transmembrane ion flow. Within that context, we summarize the regulation of TRPC channels and their coupling to receptor-mediated signaling, as well as the application of voltage-sensing phosphoinositide phosphatases to this research. We also discuss the controversial bidirectional effects of PI(4,5)P2 using a model simulation that could explain the complicated effects of PI(4,5)P2 on different ROCs.

  11. "I Can Comprehend...I Just Can't Read Big Words."

    ERIC Educational Resources Information Center

    Allen, Janet

    2003-01-01

    Explains how to help students understand the relationship between figuring out words and the ability to comprehend a text. Describes how to solidify the word-learning/comprehension connection via explaining, modeling, and supporting transfer to independence. Concludes that explaining, modeling, and supporting transfer to independence form the…

  12. The Impact of Help Seeking on Individual Task Performance: The Moderating Effect of Help Seekers' Logics of Action

    ERIC Educational Resources Information Center

    Geller, Dvora; Bamberger, Peter A.

    2012-01-01

    Drawing from achievement-goal theory and the social psychological literature on help seeking, we propose that it is the variance in the logic underpinning employees' help seeking that explains divergent findings regarding the relationship between help seeking and task performance. Using a sample of 110 newly hired customer contact employees, a…

  13. Helping for Change

    ERIC Educational Resources Information Center

    Neuringer, Allen; Oleson, Kathryn C.

    2010-01-01

    In "Helping for Change," Allen Neuringer and Kathryn Oleson describe another strategy that individuals can use to achieve their green goals. You might ask, "How can helping someone else help me change when I'm in the habit of not fulfilling my own promises?" The authors answer that question by explaining how the social reinforcement in a helping…

  14. Rare Event Simulation for T-cell Activation

    NASA Astrophysics Data System (ADS)

    Lipsmeier, Florian; Baake, Ellen

    2009-02-01

    The problem of statistical recognition is considered, as it arises in immunobiology, namely, the discrimination of foreign antigens against a background of the body's own molecules. The precise mechanism of this foreign-self-distinction, though one of the major tasks of the immune system, continues to be a fundamental puzzle. Recent progress has been made by van den Berg, Rand, and Burroughs (J. Theor. Biol. 209:465-486, 2001), who modelled the probabilistic nature of the interaction between the relevant cell types, namely, T-cells and antigen-presenting cells (APCs). Here, the stochasticity is due to the random sample of antigens present on the surface of every APC, and to the random receptor type that characterises individual T-cells. It has been shown previously (van den Berg et al. in J. Theor. Biol. 209:465-486, 2001; Zint et al. in J. Math. Biol. 57:841-861, 2008) that this model, though highly idealised, is capable of reproducing important aspects of the recognition phenomenon, and of explaining them on the basis of stochastic rare events. These results were obtained with the help of a refined large deviation theorem and were thus asymptotic in nature. Simulations have, so far, been restricted to the straightforward simple sampling approach, which does not allow for sample sizes large enough to address more detailed questions. Building on the available large deviation results, we develop an importance sampling technique that allows for a convenient exploration of the relevant tail events by means of simulation. With its help, we investigate the mechanism of statistical recognition in some depth. In particular, we illustrate how a foreign antigen can stand out against the self background if it is present in sufficiently many copies, although no a priori difference between self and nonself is built into the model.

  15. Algorithmic procedures for Bayesian MEG/EEG source reconstruction in SPM☆

    PubMed Central

    López, J.D.; Litvak, V.; Espinosa, J.J.; Friston, K.; Barnes, G.R.

    2014-01-01

    The MEG/EEG inverse problem is ill-posed, giving different source reconstructions depending on the initial assumption sets. Parametric Empirical Bayes allows one to implement most popular MEG/EEG inversion schemes (Minimum Norm, LORETA, etc.) within the same generic Bayesian framework. It also provides a cost-function in terms of the variational Free energy—an approximation to the marginal likelihood or evidence of the solution. In this manuscript, we revisit the algorithm for MEG/EEG source reconstruction with a view to providing a didactic and practical guide. The aim is to promote and help standardise the development and consolidation of other schemes within the same framework. We describe the implementation in the Statistical Parametric Mapping (SPM) software package, carefully explaining each of its stages with the help of a simple simulated data example. We focus on the Multiple Sparse Priors (MSP) model, which we compare with the well-known Minimum Norm and LORETA models, using the negative variational Free energy for model comparison. The manuscript is accompanied by Matlab scripts to allow the reader to test and explore the underlying algorithm. PMID:24041874

  16. The limitation of the proposed collection efficiency for fiber probes on the visible and near-infrared diffuse spectroscopy

    NASA Astrophysics Data System (ADS)

    Zhang, Linna; Ding, Hongyan; Lin, Ling; Wang, Yimin; Guo, Xin

    2017-12-01

    A fiber is usually used as a probe in visible and near-infrared diffuse spectra measurement. However, the use of different fiber probes in the same measurement may cause data mismatch problems. Our group has researched the influence of the parameters of fiber probe, including the aperture angle, on the diffuse spectrum by a modified Monte Carlo model. To eliminate the influence of the aperture angle, we proposed a fitted equation of correction coefficient to correct its difference in practical range. However, we did not discuss the limitation of this method. In this work, we explored the collection efficiency in different optical environment with Monte Carlo simulation method, and find the suitable conditions-weak absorbing and strong scattering media, for the proposed collection efficiency. Furthermore, we tried to explain the stability of the collection efficiency in this condition. This work gives suitable conditions for the collection efficiency. The use of collection efficiency can help reduce the influence of different measurement systems and is also helpful to the model translation.

  17. Predicting Help-Seeking Attitudes Toward Mental Health Services Among American Indian Older Adults: Is Andersen's Behavioral Model a Good Fit?

    PubMed

    Roh, Soonhee; Burnette, Catherine E; Lee, Kyoung Hag; Lee, Yeon-Shim; Martin, James I; Lawler, Michael J

    2017-01-01

    American Indian (AI) older adults are vulnerable to mental health disparities, yet very little is known about the factors associated with help-seeking for mental health services among them. The purpose of this study was to investigate the utility of Andersen's Behavioral Model in explaining AI older adults' help-seeking attitudes toward professional mental health services. Hierarchical regression analysis was used to examine predisposing, enabling, and need variables as predictors of help-seeking attitudes toward mental health services in a sample of 233 AI older adults from the Midwest. The model was found to have limited utility in the context of older AI help-seeking attitudes, as the proportion of explained variance was low. Gender, perceived stigma, social support, and physical health were significant predictors, whereas age, perceived mental health, and health insurance were not. © The Author(s) 2014.

  18. Cartilage.

    ERIC Educational Resources Information Center

    Caplan, Arnold I.

    1984-01-01

    Cartilage is a fundamental biological material that helps to shape the body and then helps to support it. Its fundamental properties of strength and resilience are explained in terms of the tissue's molecular structure. (JN)

  19. Content-Free Computer Supports for Self-Explaining: Modifiable Typing Interface and Prompting

    ERIC Educational Resources Information Center

    Chou, Chih-Yueh; Liang, Hung-Ta

    2009-01-01

    Self-explaining, which asks students to generate explanations while reading a text, is a self-constructive activity and is helpful for students' learning. Studies have revealed that prompts by a human tutor promote students' self-explanations. However, most studies on self-explaining focus on spoken self-explanations. This study investigates the…

  20. Consumer preference for seeds and seedlings of rare species impacts tree diversity at multiple scales.

    PubMed

    Young, Hillary S; McCauley, Douglas J; Guevara, Roger; Dirzo, Rodolfo

    2013-07-01

    Positive density-dependent seed and seedling predation, where herbivores selectively eat seeds or seedlings of common species, is thought to play a major role in creating and maintaining plant community diversity. However, many herbivores and seed predators are known to exhibit preferences for rare foods, which could lead to negative density-dependent predation. In this study, we first demonstrate the occurrence of increased predation of locally rare tree species by a widespread group of insular seed and seedling predators, land crabs. We then build computer simulations based on these empirical data to examine the effects of such predation on diversity patterns. Simulations show that herbivore preferences for locally rare species are likely to drive scale-dependent effects on plant community diversity: at small scales these foraging patterns decrease plant community diversity via the selective consumption of rare plant species, while at the landscape level they should increase diversity, at least for short periods, by promoting clustered local dominance of a variety of species. Finally, we compared observed patterns of plant diversity at the site to those obtained via computer simulations, and found that diversity patterns generated under simulations were highly consistent with observed diversity patterns. We posit that preference for rare species by herbivores may be prevalent in low- or moderate-diversity systems, and that these effects may help explain diversity patterns across different spatial scales in such ecosystems.

  1. Aqueous Molecular Dynamics Simulations of the M. tuberculosis Enoyl-ACP Reductase-NADH System and Its Complex with a Substrate Mimic or Diphenyl Ethers Inhibitors

    PubMed Central

    da Silva Lima, Camilo Henrique; de Alencastro, Ricardo Bicca; Kaiser, Carlos Roland; de Souza, Marcus Vinícius Nora; Rodrigues, Carlos Rangel; Albuquerque, Magaly Girão

    2015-01-01

    Molecular dynamics (MD) simulations of 12 aqueous systems of the NADH-dependent enoyl-ACP reductase from Mycobacterium tuberculosis (InhA) were carried out for up to 20–40 ns using the GROMACS 4.5 package. Simulations of the holoenzyme, holoenzyme-substrate, and 10 holoenzyme-inhibitor complexes were conducted in order to gain more insight about the secondary structure motifs of the InhA substrate-binding pocket. We monitored the lifetime of the main intermolecular interactions: hydrogen bonds and hydrophobic contacts. Our MD simulations demonstrate the importance of evaluating the conformational changes that occur close to the active site of the enzyme-cofactor complex before and after binding of the ligand and the influence of the water molecules. Moreover, the protein-inhibitor total steric (ELJ) and electrostatic (EC) interaction energies, related to Gly96 and Tyr158, are able to explain 80% of the biological response variance according to the best linear equation, pKi = 7.772 − 0.1885 × Gly96 + 0.0517 × Tyr158 (R2 = 0.80; n = 10), where interactions with Gly96, mainly electrostatic, increase the biological response, while those with Tyr158 decrease. These results will help to understand the structure-activity relationships and to design new and more potent anti-TB drugs. PMID:26457706

  2. Separator Reconnection at Earth's Dayside Magnetopause and the Tail: MMS Observations Compared to Global 3D Simulations

    NASA Astrophysics Data System (ADS)

    Buzulukova, N.; Dorelli, J.; Glocer, A.

    2017-12-01

    We present the results of global high resolution resistive magnetohydrodynamics (MHD BATS-R-US) simulations of Earth's magnetosphere. We extract location of magnetic separators with RECONX tool and compare the results with observations from the Magnetospheric Multiscale (MMS). A few cases are analysed including a southward IMF magnetopause crossing during October 16, 2015 that was previously identified as an electron diffusion region (EDR) event. The simulation predicts a complex time-dependent magnetic topology consisting of multiple separators and flux ropes. Despite the topological complexity, the predicted distance between MMS and the primary separator is less than 0.5 Earth radii. The simulation shows that the existence of IMF Bx results in a duskward shift of the location of the topological separator. The results are explained by a combined effect of solar wind draping and pile-up effect that modify the current density across the magnetopause and affect the location of the separator. The RECONX tool also is used to extract the separator location in the geomagnetic tail, and relate transient tail structures (bursty bulk flows) to the location of separator. These results suggest that global magnetic topology, rather than local magnetic geometry alone, determines the location of the separator reconnection both at the dayside magnetopause and in the tail. We show that the resistive MHD model helps to understand the global context of local MMS observations.

  3. Modeling the role of parallel processing in visual search.

    PubMed

    Cave, K R; Wolfe, J M

    1990-04-01

    Treisman's Feature Integration Theory and Julesz's Texton Theory explain many aspects of visual search. However, these theories require that parallel processing mechanisms not be used in many visual searches for which they would be useful, and they imply that visual processing should be much slower than it is. Most importantly, they cannot account for recent data showing that some subjects can perform some conjunction searches very efficiently. Feature Integration Theory can be modified so that it accounts for these data and helps to answer these questions. In this new theory, which we call Guided Search, the parallel stage guides the serial stage as it chooses display elements to process. A computer simulation of Guided Search produces the same general patterns as human subjects in a number of different types of visual search.

  4. A parametric study of transonic blade-vortex interaction noise

    NASA Technical Reports Server (NTRS)

    Lyrintzis, A. S.

    1991-01-01

    Several parameters of transonic blade-vortex interactions (BVI) are being studied and some ideas for noise reduction are introduced and tested using numerical simulation. The model used is the two-dimensional high frequency transonic small disturbance equation with regions of distributed vorticity (VTRAN2 code). The far-field noise signals are obtained by using the Kirchhoff method with extends the numerical 2-D near-field aerodynamic results to the linear acoustic 3-D far-field. The BVI noise mechanisms are explained and the effects of vortex type and strength, and angle of attack are studied. Particularly, airfoil shape modifications which lead to noise reduction are investigated. The results presented are expected to be helpful for better understanding of the nature of the BVI noise and better blade design.

  5. Influence of deep sedimentary basins, crustal thining, attenuation, and topography on regional phases: selected examples from theEastern Mediteranean and the Caspian Sea Regions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goldstein, P.; Schultz, C.; Larsen, S.

    1997-07-15

    Monitoring of a CTBT will require transportable seismic identification techniques, especially in regions where there is limited data. Unfortunately, most existing techniques are empirical and can not be used reliably in new regions. Our goal is to help develop transportable regional identification techniques by improving our ability to predict the behavior of regional phases and discriminants in diverse geologic regions and in regions with little or no data. Our approach is to use numerical modeling to understand the physical basis for regional wave propagation phenomena and to use this understanding to help explain observed behavior of regional phases and discriminants.more » In this paper, we focus on results from simulations of data in selected regions and investigate the sensitivity of these regional simulations to various features of the crustal structure. Our initial models use teleseismically estimated source locations, mechanisms, and durations and seismological structures that have been determined by others. We model the Mb 5.9, October 1992, Cairo Egypt earthquake at a station at Ankara Turkey (ANTO) using a two-dimensional crustal model consisting of a water layer over a deep sedimentary basin with a thinning crust beneath the basin. Despite the complex tectonics of the Eastern Mediterranean region, we find surprisingly good agreement between the observed data and synthetics based on this relatively smooth two-dimensional model.« less

  6. Tools and procedures for visualization of proteins and other biomolecules.

    PubMed

    Pan, Lurong; Aller, Stephen G

    2015-04-01

    Protein, peptides, and nucleic acids are biomolecules that drive biological processes in living organisms. An enormous amount of structural data for a large number of these biomolecules has been described with atomic precision in the form of structural "snapshots" that are freely available in public repositories. These snapshots can help explain how the biomolecules function, the nature of interactions between multi-molecular complexes, and even how small-molecule drugs can modulate the biomolecules for clinical benefits. Furthermore, these structural snapshots serve as inputs for sophisticated computer simulations to turn the biomolecules into moving, "breathing" molecular machines for understanding their dynamic properties in real-time computer simulations. In order for the researcher to take advantage of such a wealth of structural data, it is necessary to gain competency in the use of computer molecular visualization tools for exploring the structures and visualizing three-dimensional spatial representations. Here, we present protocols for using two common visualization tools--the Web-based Jmol and the stand-alone PyMOL package--as well as a few examples of other popular tools. Copyright © 2015 John Wiley & Sons, Inc.

  7. Simulation of a small cold-leg-break experiment at the PMK-2 test facility using the RELAP5 and ATHLET codes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ezsoel, G.; Guba, A.; Perneczky, L.

    Results of a small-break loss-of-coolant accident experiment, conducted on the PMK-2 integral-type test facility are presented. The experiment simulated a 1% break in the cold leg of a VVER-440-type reactor. The main phenomena of the experiment are discussed, and in the case of selected events, a more detailed interpretation with the help of measured void fraction, obtained by a special measurement device, is given. Two thermohydraulic computer codes, RELAP5 and ATHLET, are used for posttest calculations. The aim of these calculations is to investigate the code capability for modeling natural circulation phenomena in VVER-440-type reactors. Therefore, the results of themore » experiment and both calculations are compared. Both codes predict most of the transient events well, with the exception that RELAP5 fails to predict the dryout period in the core. In the experiment, the hot- and cold-leg loop-seal clearing is accompanied by natural circulation instabilities, which can be explained by means of the ATHLET calculation.« less

  8. Electric Field Fluctuations in Water

    NASA Astrophysics Data System (ADS)

    Thorpe, Dayton; Limmer, David; Chandler, David

    2013-03-01

    Charge transfer in solution, such as autoionization and ion pair dissociation in water, is governed by rare electric field fluctuations of the solvent. Knowing the statistics of such fluctuations can help explain the dynamics of these rare events. Trajectories short enough to be tractable by computer simulation are virtually certain not to sample the large fluctuations that promote rare events. Here, we employ importance sampling techniques with classical molecular dynamics simulations of liquid water to study statistics of electric field fluctuations far from their means. We find that the distributions of electric fields located on individual water molecules are not in general gaussian. Near the mean this non-gaussianity is due to the internal charge distribution of the water molecule. Further from the mean, however, there is a previously unreported Bjerrum-like defect that stabilizes certain large fluctuations out of equilibrium. As expected, differences in electric fields acting between molecules are gaussian to a remarkable degree. By studying these differences, though, we are able to determine what configurations result not only in large electric fields, but also in electric fields with long spatial correlations that may be needed to promote charge separation.

  9. Leakiness of Pinned Neighboring Surface Nanobubbles Induced by Strong Gas-Surface Interaction.

    PubMed

    Maheshwari, Shantanu; van der Hoef, Martin; Rodrı Guez Rodrı Guez, Javier; Lohse, Detlef

    2018-03-27

    The stability of two neighboring surface nanobubbles on a chemically heterogeneous surface is studied by molecular dynamics (MD) simulations of binary mixtures consisting of Lennard-Jones (LJ) particles. A diffusion equation-based stability analysis suggests that two nanobubbles sitting next to each other remain stable, provided the contact line is pinned, and that their radii of curvature are equal. However, many experimental observations seem to suggest some long-term kind of ripening or shrinking of the surface nanobubbles. In our MD simulations we find that the growth/dissolution of the nanobubbles can occur due to the transfer of gas particles from one nanobubble to another along the solid substrate. That is, if the interaction between the gas and the solid is strong enough, the solid-liquid interface can allow for the existence of a "tunnel" which connects the liquid-gas interfaces of the two nanobubbles to destabilize the system. The crucial role of the gas-solid interaction energy is a nanoscopic element that hitherto has not been considered in any macroscopic theory of surface nanobubbles and may help to explain experimental observations of the long-term ripening.

  10. Dwarf Galaxies and the Cosmic Web

    NASA Astrophysics Data System (ADS)

    Benítez-Llambay, Alejandro; Navarro, Julio F.; Abadi, Mario G.; Gottlöber, Stefan; Yepes, Gustavo; Hoffman, Yehuda; Steinmetz, Matthias

    2013-02-01

    We use a cosmological simulation of the formation of the Local Group of Galaxies to identify a mechanism that enables the removal of baryons from low-mass halos without appealing to feedback or reionization. As the Local Group forms, matter bound to it develops a network of filaments and pancakes. This moving web of gas and dark matter drifts and sweeps a large volume, overtaking many halos in the process. The dark matter content of these halos is unaffected but their gas can be efficiently removed by ram pressure. The loss of gas is especially pronounced in low-mass halos due to their lower binding energy and has a dramatic effect on the star formation history of affected systems. This "cosmic web stripping" may help to explain the scarcity of dwarf galaxies compared with the numerous low-mass halos expected in ΛCDM and the large diversity of star formation histories and morphologies characteristic of faint galaxies. Although our results are based on a single high-resolution simulation, it is likely that the hydrodynamical interaction of dwarf galaxies with the cosmic web is a crucial ingredient so far missing from galaxy formation models.

  11. Numerical Simulation and Scaling Analysis of Cell Printing

    NASA Astrophysics Data System (ADS)

    Qiao, Rui; He, Ping

    2011-11-01

    Cell printing, i.e., printing three dimensional (3D) structures of cells held in a tissue matrix, is gaining significant attention in the biomedical community. The key idea is to use inkjet printer or similar devices to print cells into 3D patterns with a resolution comparable to the size of mammalian cells. Achieving such a resolution in vitro can lead to breakthroughs in areas such as organ transplantation. Although the feasibility of cell printing has been demonstrated recently, the printing resolution and cell viability remain to be improved. Here we investigate a unit operation in cell printing, namely, the impact of a cell-laden droplet into a pool of highly viscous liquids. The droplet and cell dynamics are quantified using both direct numerical simulation and scaling analysis. These studies indicate that although cell experienced significant stress during droplet impact, the duration of such stress is very short, which helps explain why many cells can survive the cell printing process. These studies also revealed that cell membrane can be temporarily ruptured during cell printing, which is supported by indirect experimental evidence.

  12. QUAL-NET, a high temporal-resolution eutrophication model for large hydrographic networks

    NASA Astrophysics Data System (ADS)

    Minaudo, Camille; Curie, Florence; Jullian, Yann; Gassama, Nathalie; Moatar, Florentina

    2018-04-01

    To allow climate change impact assessment of water quality in river systems, the scientific community lacks efficient deterministic models able to simulate hydrological and biogeochemical processes in drainage networks at the regional scale, with high temporal resolution and water temperature explicitly determined. The model QUALity-NETwork (QUAL-NET) was developed and tested on the Middle Loire River Corridor, a sub-catchment of the Loire River in France, prone to eutrophication. Hourly variations computed efficiently by the model helped disentangle the complex interactions existing between hydrological and biological processes across different timescales. Phosphorus (P) availability was the most constraining factor for phytoplankton development in the Loire River, but simulating bacterial dynamics in QUAL-NET surprisingly evidenced large amounts of organic matter recycled within the water column through the microbial loop, which delivered significant fluxes of available P and enhanced phytoplankton growth. This explained why severe blooms still occur in the Loire River despite large P input reductions since 1990. QUAL-NET could be used to study past evolutions or predict future trajectories under climate change and land use scenarios.

  13. Linking market interaction intensity of 3D Ising type financial model with market volatility

    NASA Astrophysics Data System (ADS)

    Fang, Wen; Ke, Jinchuan; Wang, Jun; Feng, Ling

    2016-11-01

    Microscopic interaction models in physics have been used to investigate the complex phenomena of economic systems. The simple interactions involved can lead to complex behaviors and help the understanding of mechanisms in the financial market at a systemic level. This article aims to develop a financial time series model through 3D (three-dimensional) Ising dynamic system which is widely used as an interacting spins model to explain the ferromagnetism in physics. Through Monte Carlo simulations of the financial model and numerical analysis for both the simulation return time series and historical return data of Hushen 300 (HS300) index in Chinese stock market, we show that despite its simplicity, this model displays stylized facts similar to that seen in real financial market. We demonstrate a possible underlying link between volatility fluctuations of real stock market and the change in interaction strengths of market participants in the financial model. In particular, our stochastic interaction strength in our model demonstrates that the real market may be consistently operating near the critical point of the system.

  14. Impact of resistive MHD plasma response on perturbation field sidebands

    DOE PAGES

    Orlov, D. M.; Evans, T. E.; Moyer, R. A.; ...

    2016-06-03

    Here, single fluid linear simulations of a KSTAR RMP ELM suppressed discharge with the M3D-C 1 resistive magnetohydrodynamic code have been performed for the first time. The simulations show that the application of the n = 1 perturbation using the KSTAR in-vessel control coils (IVCC), which apply modest levels of n = 3 sidebands (~20% of the n = 1), leads to levels of n = 3 sideband that are comparable to the n = 1 when plasma response is included. This is due to the reduced level of screening of the rational-surface-resonant n = 3 component relative to themore » rational-surface-resonant n = 1 component. The n = 3 sidebands could play a similar role in ELM suppression on KSTAR as the toroidal sidebands (n = 1, 2, 4) in DIII-D n = 3 ELM suppression with missing I-coil segments. This result may help to explain the uniqueness of ELM suppression with n = 1 perturbations in KSTAR since the effective perturbation is a mixed n = 1/n = 3 perturbation similar to n = 3 ELM suppression in DIII-D.« less

  15. Simulation modeling to understand how selective foraging by beaver can drive the structure and function of a willow community

    USGS Publications Warehouse

    Peinetti, H.R.; Baker, B.W.; Coughenour, M.B.

    2009-01-01

    Beaver-willow (Castor-Salix) communities are a unique and vital component of healthy wetlands throughout the Holarctic region. Beaver selectively forage willow to provide fresh food, stored winter food, and construction material. The effects of this complex foraging behavior on the structure and function of willow communities is poorly understood. Simulation modeling may help ecologists understand these complex interactions. In this study, a modified version of the SAVANNA ecosystem model was developed to better understand how beaver foraging affects the structure and function of a willow community in a simulated riparian ecosystem in Rocky Mountain National Park, Colorado (RMNP). The model represents willow in terms of plant and stem dynamics and beaver foraging in terms of the quantity and quality of stems cut to meet the energetic and life history requirements of beaver. Given a site where all stems were equally available, the model suggested a simulated beaver family of 2 adults, 2 yearlings, and 2 kits required a minimum of 4 ha of willow (containing about10 stems m-2) to persist in a steady-state condition. Beaver created a willow community where the annual net primary productivity (ANPP) was 2 times higher and plant architecture was more diverse than the willow community without beaver. Beaver foraging created a plant architecture dominated by medium size willow plants, which likely explains how beaver can increase ANPP. Long-term simulations suggested that woody biomass stabilized at similar values even though availability differed greatly at initial condition. Simulations also suggested that willow ANPP increased across a range of beaver densities until beaver became food limited. Thus, selective foraging by beaver increased productivity, decreased biomass, and increased structural heterogeneity in a simulated willow community.

  16. Investigation of polarization effects in the gramicidin A channel from ab initio molecular dynamics simulations.

    PubMed

    Timko, Jeff; Kuyucak, Serdar

    2012-11-28

    Polarization is an important component of molecular interactions and is expected to play a particularly significant role in inhomogeneous environments such as pores and interfaces. Here we investigate the effects of polarization in the gramicidin A ion channel by performing quantum mechanics/molecular mechanics molecular dynamics (MD) simulations and comparing the results with those obtained from classical MD simulations with non-polarizable force fields. We consider the dipole moments of backbone carbonyl groups and channel water molecules as well as a number of structural quantities of interest. The ab initio results show that the dipole moments of the carbonyl groups and water molecules are highly sensitive to the hydrogen bonds (H-bonds) they participate in. In the absence of a K(+) ion, water molecules in the channel are quite mobile, making the H-bond network highly dynamic. A central K(+) ion acts as an anchor for the channel waters, stabilizing the H-bond network and thereby increasing their average dipole moments. In contrast, the K(+) ion has little effect on the dipole moments of the neighboring carbonyl groups. The weakness of the ion-peptide interactions helps to explain the near diffusion-rate conductance of K(+) ions through the channel. We also address the sampling issue in relatively short ab initio MD simulations. Results obtained from a continuous 20 ps ab initio MD simulation are compared with those generated by sampling ten windows from a much longer classical MD simulation and running each window for 2 ps with ab initio MD. Both methods yield similar results for a number of quantities of interest, indicating that fluctuations are fast enough to justify the short ab initio MD simulations.

  17. Parent and Student Guide to High School Superintendent Suspension Hearings.

    ERIC Educational Resources Information Center

    Advocates for Children of New York, Inc., Long Island City.

    This guide has been written to help parents represent their children at New York City Board of Education hearings. The guide explains the rights of parents and children and explains the steps a parent should take in representing the child. It only applies to regular education high school suspensions. Sections of the guide explain: (1) reasons a…

  18. Losing physics Pictionary

    NASA Astrophysics Data System (ADS)

    2017-06-01

    Physics is often best explained with the help of a diagram, as anyone who has ever tried to explain the photoelectric effect will attest to. Drawing Physics by Don S Lemons looks back on how this has been the case throughout history.

  19. Break-even Analysis: A Practical Tool for Administrators of Continuing Education.

    ERIC Educational Resources Information Center

    Noel, James

    1982-01-01

    Explains how break-even analysis can help the continuing education administrator in planning by clarifying the relationship between costs, volume, and surplus revenues. Also explains the concepts of fixed, variable, and semivariable costs. (CT)

  20. The Elements of Effective Communication

    ERIC Educational Resources Information Center

    Hunter, Madeline

    1969-01-01

    Explains elements of helping children communicate: (1) recognize the need for child sending a message, (2) help him to put the message into language, (3) allow transmission of the message, and (4) decode the message. (DR)

  1. Nonlinear simulations of Jupiter's 5-micron hot spots

    NASA Technical Reports Server (NTRS)

    Showman, A. P.; Dowling, T. E.

    2000-01-01

    Large-scale nonlinear simulations of Jupiter's 5-micron hot spots produce long-lived coherent structures that cause subsidence in local regions, explaining the low cloudiness and the dryness measured by the Galileo probe inside a hot spot. Like observed hot spots, the simulated coherent structures are equatorially confined, have periodic spacing, propagate west relative to the flow, are generally confined to one hemisphere, and have an anticyclonic gyre on their equatorward side. The southern edge of the simulated hot spots develops vertical shear of up to 70 meters per second in the eastward wind, which can explain the results of the Galileo probe Doppler wind experiment.

  2. Unexpected extreme events drive the inter-annual variabilty in carbon exchange at the Pine forest in Netherlands.

    NASA Astrophysics Data System (ADS)

    Sethi, Sanjna; Moors, Eddy; Jamir, Chubamenla

    2017-04-01

    The carbon exchange between vegetation and the atmosphere tends to vary on an annual basis. This change is a continuous process its trend emerging over a period of years can be analysed. In any such trend over a prolonged period, some years stand out more than the others on account of extreme events. Explaining deviations from the expected average emissions may help to understand the drivers behind these interannual deviations. Such noticeable deviations in trend maybe on account of extreme events and need to be analysed in overall context of the ecosystem. This research's focus is to identify the main drivers responsible for the deviations, and how extreme events impact the variability over a prolonged period of time. The hypothesis being that extreme events are driving these deviations. Carbon flux data done for multiple years (1997-2015) for a site at the Loobos Pine Forest is used and compared with an ecosystem model, LPJ-GUESS (Lund-Potsdam-Jena General Ecosystem Simulator) to understand if the deviation of measured data from the simulated data is on account of extreme events on a monthly and daily basis. A Principal Component Analysis is performed on the identified deviations between measured and simulated carbon exchange to pin point the main cause behind their occurrence.​

  3. Understanding the impact of Fc glycosylation on its conformational changes by molecular dynamics simulations and bioinformatics.

    PubMed

    Zhang, Yubo

    2015-12-01

    N-linked glycosylation of Fc at N297 plays an important role in its effector function, aberrance of which would cause disease pathogenesis. Here, we performed all-atom molecular dynamics simulations to explore the effects of Fc glycosylation on its dynamics behaviors. Firstly, equilibrium simulations suggested that Fc deglycosylation was able to induce residual flexibility in its CH2 domain. Besides, the free energy landscape revealed three minimum energy wells in deglycosylated Fc, representing its "open", "semi-closed" and "closed" states. However, we could only observe the "open" state of glycosylated Fc. Supportively, principal component analysis emphasized the prominent motion of delyclosylated Fc and dynamically depicted how it changed from the "open" state to its "closed" state. Secondly, we studied the recognition mechanism of the Fc binding to its partners. Energy decomposition analysis identified key residues of Fc to recognize its two partners P13 and P34. Evidently, electrostatic potential surfaces showed that electrostatic attraction helped to stabilize the interaction between Fc and its partners. Also, relative binding free energies explained different binding affinities in Fc-P13 and Fc-P34. Collectively, these results together provided the structural basis for understanding conformational changes of deglycosylated Fc and the recognition mechanism of the Fc binding to its partners.

  4. Different sensitivities of snowpacks to warming in Mediterranean climate mountain areas

    NASA Astrophysics Data System (ADS)

    López-Moreno, J. I.; Gascoin, S.; Herrero, J.; Sproles, E. A.; Pons, M.; Alonso-González, E.; Hanich, L.; Boudhar, A.; Musselman, K. N.; Molotch, N. P.; Sickman, J.; Pomeroy, J.

    2017-07-01

    In this study we quantified the sensitivity of snow to climate warming in selected mountain sites having a Mediterranean climate, including the Pyrenees in Spain and Andorra, the Sierra Nevada in Spain and California (USA), the Atlas in Morocco, and the Andes in Chile. Meteorological observations from high elevations were used to simulate the snow energy and mass balance (SEMB) and calculate its sensitivity to climate. Very different climate sensitivities were evident amongst the various sites. For example, reductions of 9%-19% and 6-28 days in the mean snow water equivalent (SWE) and snow duration, respectively, were found per °C increase. Simulated changes in precipitation (±20%) did not affect the sensitivities. The Andes and Atlas Mountains have a shallow and cold snowpack, and net radiation dominates the SEMB; and explains their relatively low sensitivity to climate warming. The Pyrenees and USA Sierra Nevada have a deeper and warmer snowpack, and sensible heat flux is more important in the SEMB; this explains the much greater sensitivities of these regions. Differences in sensitivity help explain why, in regions where climate models project relatively greater temperature increases and drier conditions by 2050 (such as the Spanish Sierra Nevada and the Moroccan Atlas Mountains), the decline in snow accumulation and duration is similar to other sites (such as the Pyrenees and the USA Sierra Nevada), where models project stable precipitation and more attenuated warming. The snowpack in the Andes (Chile) exhibited the lowest sensitivity to warming, and is expected to undergo only moderate change (a decrease of <12% in mean SWE, and a reduction of < 7 days in snow duration under RCP 4.5). Snow accumulation and duration in the other regions are projected to decrease substantially (a minimum of 40% in mean SWE and 15 days in snow duration) by 2050.

  5. Why does it run in families? Explaining family similarity in help-seeking behaviour by shared circumstances, socialisation and selection.

    PubMed

    Cardol, Mieke; Groenewegen, Peter P; Spreeuwenberg, Peter; Van Dijk, Liset; Van Den Bosch, Wil J H M; De Bakker, Dinny H

    2006-08-01

    Why do contact frequencies with general practice of family members resemble each other? Many aspects related to the clustering of health-care utilisation within families have been studied, but the underlying mechanisms have not been addressed. This article considers whether family similarity in contact frequency with general practice can be explained as (a) a result of shared circumstances, (b) through socialisation, and (c) through homogeneity of background characteristics. Data from the second Dutch national survey of general practice were used to test these mechanisms empirically. This survey recorded all consultations in 2001 for 104 general practices in the Netherlands, serving 385,461 patients. Information about socio-demographic characteristics was collected by means of a patient survey. In a random sample, an extended health interview took place (n=12,699). Overall, we were able to show that having determinants in common through socialisation and shared circumstances can explain similarity in contact frequencies within families, but not all hypotheses could be confirmed. In specific terms, this study shows that resemblances in contact frequencies within families can be best explained by spending more time together (socialisation) and parents and children consulting a general practitioner simultaneously (circumstances of the moment). For general practitioners, the mechanisms identified can serve as a framework for a family case history. The importance of the mechanism of socialisation in explaining similarities in help-seeking behaviour between family members points to the significance of knowledge and health beliefs underlying consultation behaviour. An integrated framework including these aspects can help to better explain health behaviour.

  6. Training across Cultures: What To Expect.

    ERIC Educational Resources Information Center

    Weech, William A.

    2001-01-01

    Discusses four critical dimensions that help explain the variation in cultural expectations: (1) egalitarianism versus hierarchy; (2) individualism versus collectivism; (3) achievement versus relationship orientation; and (4) loose versus tight structure. Explains how to apply these dimensions in training. (JOW)

  7. A Primer on Simulation and Gaming.

    ERIC Educational Resources Information Center

    Barton, Richard F.

    In a primer intended for the administrative professions, for the behavioral sciences, and for education, simulation and its various aspects are defined, illustrated, and explained. Man-model simulation, man-computer simulation, all-computer simulation, and analysis are discussed as techniques for studying object systems (parts of the "real…

  8. Breeding Young as a Survival Strategy during Earth’s Greatest Mass Extinction

    NASA Astrophysics Data System (ADS)

    Botha-Brink, Jennifer; Codron, Daryl; Huttenlocker, Adam K.; Angielczyk, Kenneth D.; Ruta, Marcello

    2016-04-01

    Studies of the effects of mass extinctions on ancient ecosystems have focused on changes in taxic diversity, morphological disparity, abundance, behaviour and resource availability as key determinants of group survival. Crucially, the contribution of life history traits to survival during terrestrial mass extinctions has not been investigated, despite the critical role of such traits for population viability. We use bone microstructure and body size data to investigate the palaeoecological implications of changes in life history strategies in the therapsid forerunners of mammals before and after the Permo-Triassic Mass Extinction (PTME), the most catastrophic crisis in Phanerozoic history. Our results are consistent with truncated development, shortened life expectancies, elevated mortality rates and higher extinction risks amongst post-extinction species. Various simulations of ecological dynamics indicate that an earlier onset of reproduction leading to shortened generation times could explain the persistence of therapsids in the unpredictable, resource-limited Early Triassic environments, and help explain observed body size distributions of some disaster taxa (e.g., Lystrosaurus). Our study accounts for differential survival in mammal ancestors after the PTME and provides a methodological framework for quantifying survival strategies in other vertebrates during major biotic crises.

  9. Numerical models of caldera deformation: Effects of multiphase and multicomponent hydrothermal fluid flow

    USGS Publications Warehouse

    Hutnak, M.; Hurwitz, S.; Ingebritsen, S.E.; Hsieh, P.A.

    2009-01-01

    Ground surface displacement (GSD) in large calderas is often interpreted as resulting from magma intrusion at depth. Recent advances in geodetic measurements of GSD, notably interferometric synthetic aperture radar, reveal complex and multifaceted deformation patterns that often require complex source models to explain the observed GSD. Although hydrothermal fluids have been discussed as a possible deformation agent, very few quantitative studies addressing the effects of multiphase flow on crustal mechanics have been attempted. Recent increases in the power and availability of computing resources allow robust quantitative assessment of the complex time-variant thermal interplay between aqueous fluid flow and crustal deformation. We carry out numerical simulations of multiphase (liquid-gas), multicomponent (H 2O-CO2) hydrothermal fluid flow and poroelastic deformation using a range of realistic physical parameters and processes. Hydrothermal fluid injection, circulation, and gas formation can generate complex, temporally and spatially varying patterns of GSD, with deformation rates, magnitudes, and geometries (including subsidence) similar to those observed in several large calderas. The potential for both rapid and gradual deformation resulting from magma-derived fluids suggests that hydrothermal fluid circulation may help explain deformation episodes at calderas that have not culminated in magmatic eruption.

  10. Reliability and the adaptive utility of discrimination among alarm callers.

    PubMed

    Blumstein, Daniel T; Verneyre, Laure; Daniel, Janice C

    2004-09-07

    Unlike individually distinctive contact calls, or calls that aid in the recognition of young by their parents, the function or functions of individually distinctive alarm calls is less obvious. We conducted three experiments to study the importance of caller reliability in explaining individual-discriminative abilities in the alarm calls of yellow-bellied marmots (Marmota flaviventris). In our first two experiments, we found that calls from less reliable individuals and calls from individuals calling from a greater simulated distance were more evocative than calls from reliable individuals or nearby callers. These results are consistent with the hypothesis that marmots assess the reliability of callers to help them decide how much time to allocate to independent vigilance. The third experiment demonstrated that the number of callers influenced responsiveness, probably because situations where more than a single caller calls, are those when there is certain to be a predator present. Taken together, the results from all three experiments demonstrate the importance of reliability in explaining individual discrimination abilities in yellow-bellied marmots. Marmots' assessment of reliability acts by influencing the time allocated to individual assessment and thus the time not allocated to other activities.

  11. Reliability and the adaptive utility of discrimination among alarm callers.

    PubMed Central

    Blumstein, Daniel T.; Verneyre, Laure; Daniel, Janice C.

    2004-01-01

    Unlike individually distinctive contact calls, or calls that aid in the recognition of young by their parents, the function or functions of individually distinctive alarm calls is less obvious. We conducted three experiments to study the importance of caller reliability in explaining individual-discriminative abilities in the alarm calls of yellow-bellied marmots (Marmota flaviventris). In our first two experiments, we found that calls from less reliable individuals and calls from individuals calling from a greater simulated distance were more evocative than calls from reliable individuals or nearby callers. These results are consistent with the hypothesis that marmots assess the reliability of callers to help them decide how much time to allocate to independent vigilance. The third experiment demonstrated that the number of callers influenced responsiveness, probably because situations where more than a single caller calls, are those when there is certain to be a predator present. Taken together, the results from all three experiments demonstrate the importance of reliability in explaining individual discrimination abilities in yellow-bellied marmots. Marmots' assessment of reliability acts by influencing the time allocated to individual assessment and thus the time not allocated to other activities. PMID:15315902

  12. Breeding Young as a Survival Strategy during Earth's Greatest Mass Extinction.

    PubMed

    Botha-Brink, Jennifer; Codron, Daryl; Huttenlocker, Adam K; Angielczyk, Kenneth D; Ruta, Marcello

    2016-04-05

    Studies of the effects of mass extinctions on ancient ecosystems have focused on changes in taxic diversity, morphological disparity, abundance, behaviour and resource availability as key determinants of group survival. Crucially, the contribution of life history traits to survival during terrestrial mass extinctions has not been investigated, despite the critical role of such traits for population viability. We use bone microstructure and body size data to investigate the palaeoecological implications of changes in life history strategies in the therapsid forerunners of mammals before and after the Permo-Triassic Mass Extinction (PTME), the most catastrophic crisis in Phanerozoic history. Our results are consistent with truncated development, shortened life expectancies, elevated mortality rates and higher extinction risks amongst post-extinction species. Various simulations of ecological dynamics indicate that an earlier onset of reproduction leading to shortened generation times could explain the persistence of therapsids in the unpredictable, resource-limited Early Triassic environments, and help explain observed body size distributions of some disaster taxa (e.g., Lystrosaurus). Our study accounts for differential survival in mammal ancestors after the PTME and provides a methodological framework for quantifying survival strategies in other vertebrates during major biotic crises.

  13. A Multi-Stage Method for Connecting Participatory Sensing and Noise Simulations

    PubMed Central

    Hu, Mingyuan; Che, Weitao; Zhang, Qiuju; Luo, Qingli; Lin, Hui

    2015-01-01

    Most simulation-based noise maps are important for official noise assessment but lack local noise characteristics. The main reasons for this lack of information are that official noise simulations only provide information about expected noise levels, which is limited by the use of large-scale monitoring of noise sources, and are updated infrequently. With the emergence of smart cities and ubiquitous sensing, the possible improvements enabled by sensing technologies provide the possibility to resolve this problem. This study proposed an integrated methodology to propel participatory sensing from its current random and distributed sampling origins to professional noise simulation. The aims of this study were to effectively organize the participatory noise data, to dynamically refine the granularity of the noise features on road segments (e.g., different portions of a road segment), and then to provide a reasonable spatio-temporal data foundation to support noise simulations, which can be of help to researchers in understanding how participatory sensing can play a role in smart cities. This study first discusses the potential limitations of the current participatory sensing and simulation-based official noise maps. Next, we explain how participatory noise data can contribute to a simulation-based noise map by providing (1) spatial matching of the participatory noise data to the virtual partitions at a more microscopic level of road networks; (2) multi-temporal scale noise estimations at the spatial level of virtual partitions; and (3) dynamic aggregation of virtual partitions by comparing the noise values at the relevant temporal scale to form a dynamic segmentation of each road segment to support multiple spatio-temporal noise simulations. In this case study, we demonstrate how this method could play a significant role in a simulation-based noise map. Together, these results demonstrate the potential benefits of participatory noise data as dynamic input sources for noise simulations on multiple spatio-temporal scales. PMID:25621604

  14. A multi-stage method for connecting participatory sensing and noise simulations.

    PubMed

    Hu, Mingyuan; Che, Weitao; Zhang, Qiuju; Luo, Qingli; Lin, Hui

    2015-01-22

    Most simulation-based noise maps are important for official noise assessment but lack local noise characteristics. The main reasons for this lack of information are that official noise simulations only provide information about expected noise levels, which is limited by the use of large-scale monitoring of noise sources, and are updated infrequently. With the emergence of smart cities and ubiquitous sensing, the possible improvements enabled by sensing technologies provide the possibility to resolve this problem. This study proposed an integrated methodology to propel participatory sensing from its current random and distributed sampling origins to professional noise simulation. The aims of this study were to effectively organize the participatory noise data, to dynamically refine the granularity of the noise features on road segments (e.g., different portions of a road segment), and then to provide a reasonable spatio-temporal data foundation to support noise simulations, which can be of help to researchers in understanding how participatory sensing can play a role in smart cities. This study first discusses the potential limitations of the current participatory sensing and simulation-based official noise maps. Next, we explain how participatory noise data can contribute to a simulation-based noise map by providing (1) spatial matching of the participatory noise data to the virtual partitions at a more microscopic level of road networks; (2) multi-temporal scale noise estimations at the spatial level of virtual partitions; and (3) dynamic aggregation of virtual partitions by comparing the noise values at the relevant temporal scale to form a dynamic segmentation of each road segment to support multiple spatio-temporal noise simulations. In this case study, we demonstrate how this method could play a significant role in a simulation-based noise map. Together, these results demonstrate the potential benefits of participatory noise data as dynamic input sources for noise simulations on multiple spatio-temporal scales.

  15. Exploring the MIS M2 glaciation occurring during a warm and high atmospheric CO2 Pliocene background climate

    NASA Astrophysics Data System (ADS)

    Tan, Ning; Ramstein, Gilles; Dumas, Christophe; Contoux, Camille; Ladant, Jean-Baptiste; Sepulchre, Pierre; Zhang, Zhongshi; De Schepper, Stijn

    2017-08-01

    Prior to the Northern Hemisphere glaciation around ∼2.7 Ma, a large global glaciation corresponding to a 20 to 60 m sea-level drop occurred during Marine Isotope Stage (MIS) M2 (3.312-3.264 Ma), interrupted the period of global warmth and high CO2 concentration (350-450 ppmv) of the mid Piacenzian. Unlike the late Quaternary glaciations, the M2 glaciation only lasted 50 kyrs and occurred under uncertain CO2 concentration (220-390 ppmv). The mechanisms causing the onset and termination of the M2 glaciation remain enigmatic, but a recent geological hypothesis suggests that the re-opening and closing of the shallow Central American Seaway (CAS) might have played a key role. In this article, thanks to a series of climate simulations carried out using a fully coupled Atmosphere Ocean General Circulation Model (GCM) and a dynamic ice sheet model, we show that re-opening of the shallow CAS helps precondition the low-latitude oceanic circulation and affects the related northward energy transport, but cannot alone explain the onset of the M2 glaciation. The presence of a shallow open CAS, together with favourable orbital parameters, 220 ppmv of CO2 concentration, and the related vegetation and ice sheet feedback, led to a global ice sheet build-up producing a global sea-level drop in the lowest range of proxy-derived estimates. More importantly, our results show that the simulated closure of the CAS has a negligible impact on the NH ice sheet melt and cannot explain the MIS M2 termination.

  16. Research of the impact of coupling between unit cells on performance of linear-to-circular polarization conversion metamaterial with half transmission and half reflection

    NASA Astrophysics Data System (ADS)

    Guo, Mengchao; Zhou, Kan; Wang, Xiaokun; Zhuang, Haiyan; Tang, Dongming; Zhang, Baoshan; Yang, Yi

    2018-04-01

    In this paper, the impact of coupling between unit cells on the performance of linear-to-circular polarization conversion metamaterial with half transmission and half reflection is analyzed by changing the distance between the unit cells. An equivalent electrical circuit model is then built to explain it based on the analysis. The simulated results show that, when the distance between the unit cells is 23 mm, this metamaterial converts half of the incident linearly-polarized wave into reflected left-hand circularly-polarized wave and converts the other half of it into transmitted left-hand circularly-polarized wave at 4.4 GHz; when the distance is 28 mm, this metamaterial reflects all of the incident linearly-polarized wave at 4.4 GHz; and when the distance is 32 mm, this metamaterial converts half of the incident linearly-polarized wave into reflected right-hand circularly-polarized wave and converts the other half of it into transmitted right-hand circularly-polarized wave at 4.4 GHz. The tunability is realized successfully. The analysis shows that the changes of coupling between unit cells lead to the changes of performance of this metamaterial. The coupling between the unit cells is then considered when building the equivalent electrical circuit model. The built equivalent electrical circuit model can be used to perfectly explain the simulated results, which confirms the validity of it. It can also give help to the design of tunable polarization conversion metamaterials.

  17. The variance of the locally measured Hubble parameter explained with different estimators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Odderskov, Io; Hannestad, Steen; Brandbyge, Jacob, E-mail: isho07@phys.au.dk, E-mail: sth@phys.au.dk, E-mail: jacobb@phys.au.dk

    We study the expected variance of measurements of the Hubble constant, H {sub 0}, as calculated in either linear perturbation theory or using non-linear velocity power spectra derived from N -body simulations. We compare the variance with that obtained by carrying out mock observations in the N-body simulations, and show that the estimator typically used for the local Hubble constant in studies based on perturbation theory is different from the one used in studies based on N-body simulations. The latter gives larger weight to distant sources, which explains why studies based on N-body simulations tend to obtain a smaller variancemore » than that found from studies based on the power spectrum. Although both approaches result in a variance too small to explain the discrepancy between the value of H {sub 0} from CMB measurements and the value measured in the local universe, these considerations are important in light of the percent determination of the Hubble constant in the local universe.« less

  18. My Brother Bit Me! Parenting Siblings. Study Guide.

    ERIC Educational Resources Information Center

    Schrank, Louise Welsh

    This videotape viewers' guide is intended to help facilitate instruction in managing sibling conflict. The guide first provides an overview of the 19-minute videotape which explains how parents can help children learn to solve conflicts on their own and why parents need to establish clear family policies to help siblings get along and maintain…

  19. Online Help to End-Users in a Networked Environment.

    ERIC Educational Resources Information Center

    Meyer, Paul

    1991-01-01

    Discusses the need for online help for end-users based on experiences with an online public access catalog (OPAC) at the University of Cape Town libraries. The concept of end users is examined, the role of search intermediaries in information systems is explained, and online help and systems design is discussed. (LRW)

  20. Bereaved Adults' Evaluations of Grief Management Messages: Effects of Message Person Centeredness, Recipient Individual Differences, and Contextual Factors

    ERIC Educational Resources Information Center

    Rack, Jessica; Burleson, Brant; Bodie, Graham; Holmstrom, Amanda; Servaty-Seib, Heather

    2008-01-01

    This study identifies grief management strategies that bereaved adults evaluate as more and less helpful, assesses whether the person centeredness of these strategies explains their helpfulness, and determines whether strategy helpfulness varies as a function of demographic, personality, and situational factors. Participants (105 bereaved young…

  1. A role for affect in the link between episodic simulation and prosociality.

    PubMed

    Gaesser, Brendan; DiBiase, Haley D; Kensinger, Elizabeth A

    2017-09-01

    Prospection and prosociality are hallmarks of our species. Little is known, however, about how our ability to imagine or simulate specific future events contributes to our capacity for prosociality. Here, we investigated this relationship, revealing how the affective response that arises from a simulated prosocial event motivates a willingness to help a person in need. Across two experiments, people reported being more willing to help in specific situations after simulating future helping events that elicited positive (versus negative or neutral) affect. Positive affect increased engagement of theory of mind for the person in need, which in turn informed prosocial responses. Moreover, the subjective experience of scene imagery and theory of mind systematically couple together depending on the affective valence of future simulations, providing new insight into how affective valence guides a prosocial function of episodic simulation.

  2. pysimm: A Python Package for Simulation of Molecular Systems

    NASA Astrophysics Data System (ADS)

    Fortunato, Michael; Colina, Coray

    pysimm, short for python simulation interface for molecular modeling, is a python package designed to facilitate the structure generation and simulation of molecular systems through convenient and programmatic access to object-oriented representations of molecular system data. This poster presents core features of pysimm and design philosophies that highlight a generalized methodology for incorporation of third-party software packages through API interfaces. The integration with the LAMMPS simulation package is explained to demonstrate this methodology. pysimm began as a back-end python library that powered a cloud-based application on nanohub.org for amorphous polymer simulation. The extension from a specific application library to general purpose simulation interface is explained. Additionally, this poster highlights the rapid development of new applications to construct polymer chains capable of controlling chain morphology such as molecular weight distribution and monomer composition.

  3. Combining Interactive Thermodynamics Simulations with Screencasts and Conceptests

    ERIC Educational Resources Information Center

    Falconer, John L.

    2016-01-01

    More than 40 interactive "Mathematica" simulations were prepared for chemical engineering thermodynamics, screencasts were prepared that explain how to use each simulation, and more than 100 ConcepTests were prepared that utilize the simulations. They are located on www.LearnChemE.com. The purposes of these simulations are to clarify…

  4. Evolutionary genomics of Entamoeba

    PubMed Central

    Weedall, Gareth D.; Hall, Neil

    2011-01-01

    Entamoeba histolytica is a human pathogen that causes amoebic dysentery and leads to significant morbidity and mortality worldwide. Understanding the genome and evolution of the parasite will help explain how, when and why it causes disease. Here we review current knowledge about the evolutionary genomics of Entamoeba: how differences between the genomes of different species may help explain different phenotypes, and how variation among E. histolytica parasites reveals patterns of population structure. The imminent expansion of the amount genome data will greatly improve our knowledge of the genus and of pathogenic species within it. PMID:21288488

  5. Investigation on wind energy-compressed air power system.

    PubMed

    Jia, Guang-Zheng; Wang, Xuan-Yin; Wu, Gen-Mao

    2004-03-01

    Wind energy is a pollution free and renewable resource widely distributed over China. Aimed at protecting the environment and enlarging application of wind energy, a new approach to application of wind energy by using compressed air power to some extent instead of electricity put forward. This includes: explaining the working principles and characteristics of the wind energy-compressed air power system; discussing the compatibility of wind energy and compressor capacity; presenting the theoretical model and computational simulation of the system. The obtained compressor capacity vs wind power relationship in certain wind velocity range can be helpful in the designing of the wind power-compressed air system. Results of investigations on the application of high-pressure compressed air for pressure reduction led to conclusion that pressure reduction with expander is better than the throttle regulator in energy saving.

  6. Computational neurobiology is a useful tool in translational neurology: the example of ataxia

    PubMed Central

    Brown, Sherry-Ann; McCullough, Louise D.; Loew, Leslie M.

    2014-01-01

    Hereditary ataxia, or motor incoordination, affects approximately 150,000 Americans and hundreds of thousands of individuals worldwide with onset from as early as mid-childhood. Affected individuals exhibit dysarthria, dysmetria, action tremor, and diadochokinesia. In this review, we consider an array of computational studies derived from experimental observations relevant to human neuropathology. A survey of related studies illustrates the impact of integrating clinical evidence with data from mouse models and computational simulations. Results from these studies may help explain findings in mice, and after extensive laboratory study, may ultimately be translated to ataxic individuals. This inquiry lays a foundation for using computation to understand neurobiochemical and electrophysiological pathophysiology of spinocerebellar ataxias and may contribute to development of therapeutics. The interdisciplinary analysis suggests that computational neurobiology can be an important tool for translational neurology. PMID:25653585

  7. An Empirical Agent-Based Model to Simulate the Adoption of Water Reuse Using the Social Amplification of Risk Framework.

    PubMed

    Kandiah, Venu; Binder, Andrew R; Berglund, Emily Z

    2017-10-01

    Water reuse can serve as a sustainable alternative water source for urban areas. However, the successful implementation of large-scale water reuse projects depends on community acceptance. Because of the negative perceptions that are traditionally associated with reclaimed water, water reuse is often not considered in the development of urban water management plans. This study develops a simulation model for understanding community opinion dynamics surrounding the issue of water reuse, and how individual perceptions evolve within that context, which can help in the planning and decision-making process. Based on the social amplification of risk framework, our agent-based model simulates consumer perceptions, discussion patterns, and their adoption or rejection of water reuse. The model is based on the "risk publics" model, an empirical approach that uses the concept of belief clusters to explain the adoption of new technology. Each household is represented as an agent, and parameters that define their behavior and attributes are defined from survey data. Community-level parameters-including social groups, relationships, and communication variables, also from survey data-are encoded to simulate the social processes that influence community opinion. The model demonstrates its capabilities to simulate opinion dynamics and consumer adoption of water reuse. In addition, based on empirical data, the model is applied to investigate water reuse behavior in different regions of the United States. Importantly, our results reveal that public opinion dynamics emerge differently based on membership in opinion clusters, frequency of discussion, and the structure of social networks. © 2017 Society for Risk Analysis.

  8. Understanding resonance graphs using Easy Java Simulations (EJS) and why we use EJS

    NASA Astrophysics Data System (ADS)

    Wee, Loo Kang; Lee, Tat Leong; Chew, Charles; Wong, Darren; Tan, Samuel

    2015-03-01

    This paper reports a computer model simulation created using Easy Java Simulation (EJS) for learners to visualize how the steady-state amplitude of a driven oscillating system varies with the frequency of the periodic driving force. The simulation shows (N = 100) identical spring-mass systems being subjected to (1) a periodic driving force of equal amplitude but different driving frequencies, and (2) different amounts of damping. The simulation aims to create a visually intuitive way of understanding how the series of amplitude versus driving frequency graphs are obtained by showing how the displacement of the system changes over time as it transits from the transient to the steady state. A suggested ‘how to use’ the model is added to help educators and students in their teaching and learning, where we explain the theoretical steady-state equation time conditions when the model begins to allow data recording of maximum amplitudes to closely match the theoretical equation, and the steps to collect different runs of the degree of damping. We also discuss two of the design features in our computer model: displaying the instantaneous oscillation together with the achieved steady-state amplitudes, and the explicit world view overlay with scientific representation with different degrees of damping runs. Three advantages of using EJS include: (1) open source codes and creative commons attribution licenses for scaling up of interactively engaging educational practices; (2) the models made can run on almost any device, including Android and iOS; and (3) it allows the redefinition of physics educational practices through computer modeling.

  9. Quantitative Comparison of the Variability in Observed and Simulated Shortwave Reflectance

    NASA Technical Reports Server (NTRS)

    Roberts, Yolanda, L.; Pilewskie, P.; Kindel, B. C.; Feldman, D. R.; Collins, W. D.

    2013-01-01

    The Climate Absolute Radiance and Refractivity Observatory (CLARREO) is a climate observation system that has been designed to monitor the Earth's climate with unprecedented absolute radiometric accuracy and SI traceability. Climate Observation System Simulation Experiments (OSSEs) have been generated to simulate CLARREO hyperspectral shortwave imager measurements to help define the measurement characteristics needed for CLARREO to achieve its objectives. To evaluate how well the OSSE-simulated reflectance spectra reproduce the Earth s climate variability at the beginning of the 21st century, we compared the variability of the OSSE reflectance spectra to that of the reflectance spectra measured by the Scanning Imaging Absorption Spectrometer for Atmospheric Cartography (SCIAMACHY). Principal component analysis (PCA) is a multivariate decomposition technique used to represent and study the variability of hyperspectral radiation measurements. Using PCA, between 99.7%and 99.9%of the total variance the OSSE and SCIAMACHY data sets can be explained by subspaces defined by six principal components (PCs). To quantify how much information is shared between the simulated and observed data sets, we spectrally decomposed the intersection of the two data set subspaces. The results from four cases in 2004 showed that the two data sets share eight (January and October) and seven (April and July) dimensions, which correspond to about 99.9% of the total SCIAMACHY variance for each month. The spectral nature of these shared spaces, understood by examining the transformed eigenvectors calculated from the subspace intersections, exhibit similar physical characteristics to the original PCs calculated from each data set, such as water vapor absorption, vegetation reflectance, and cloud reflectance.

  10. A multimodel intercomparison of resolution effects on precipitation: simulations and theory

    DOE PAGES

    Rauscher, Sara A.; O?Brien, Travis A.; Piani, Claudio; ...

    2016-02-27

    An ensemble of six pairs of RCM experiments performed at 25 and 50 km for the period 1961–2000 over a large European domain is examined in order to evaluate the effects of resolution on the simulation of daily precipitation statistics. Application of the non-parametric two-sample Kolmorgorov–Smirnov test, which tests for differences in the location and shape of the probability distributions of two samples, shows that the distribution of daily precipitation differs between the pairs of simulations over most land areas in both summer and winter, with the strongest signal over southern Europe. Two-dimensional histograms reveal that precipitation intensity increases with resolutionmore » over almost the entire domain in both winter and summer. In addition, the 25 km simulations have more dry days than the 50 km simulations. The increase in dry days with resolution is indicative of an improvement in model performance at higher resolution, while the more intense precipitation exceeds observed values. The systematic increase in precipitation extremes with resolution across all models suggests that this response is fundamental to model formulation. Simple theoretical arguments suggest that fluid continuity, combined with the emergent scaling properties of the horizontal wind field, results in an increase in resolved vertical transport as grid spacing decreases. This increase in resolution-dependent vertical mass flux then drives an intensification of convergence and resolvable-scale precipitation as grid spacing decreases. In conclusion, this theoretical result could help explain the increasingly, and often anomalously, large stratiform contribution to total rainfall observed with increasing resolution in many regional and global models.« less

  11. Plasma Science and Innovation Center (PSI-Center) at Washington, Wisconsin, and Utah State, ARRA Supplement

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sovinec, Carl

    The objective of the Plasma Science and Innovation Center (PSI-Center) is to develop and deploy computational models that simulate conditions in smaller, concept-exploration plasma experiments. The PSIC group at the University of Wisconsin-Madison, led by Prof. Carl Sovinec, uses and enhances the Non-Ideal Magnetohydrodynamics with Rotation, Open Discussion (NIMROD) code, to simulate macroscopic plasma dynamics in a number of magnetic confinement configurations. These numerical simulations provide information on how magnetic fields and plasma flows evolve over all three spatial dimensions, which supplements the limited access of diagnostics in plasma experiments. The information gained from simulation helps explain how plasma evolves.more » It is also used to engineer more effective plasma confinement systems, reducing the need for building many experiments to cover the physical parameter space. The ultimate benefit is a more cost-effective approach to the development of fusion energy for peaceful power production. The supplemental funds provided by the American Recovery and Reinvestment Act of 2009 were used to purchase computer components that were assembled into a 48-core system with 256 Gb of shared memory. The system was engineered and constructed by the group's system administrator at the time, Anthony Hammond. It was successfully used by then graduate student, Dr. John O'Bryan, for computing magnetic relaxation dynamics that occur during experimental tests of non-inductive startup in the Pegasus Toroidal Experiment (pegasus.ep.wisc.edu). Dr. O'Bryan's simulations provided the first detailed explanation of how the driven helical filament of electrical current evolves into a toroidal tokamak-like plasma configuration.« less

  12. A multimodel intercomparison of resolution effects on precipitation: simulations and theory

    NASA Astrophysics Data System (ADS)

    Rauscher, Sara A.; O'Brien, Travis A.; Piani, Claudio; Coppola, Erika; Giorgi, Filippo; Collins, William D.; Lawston, Patricia M.

    2016-10-01

    An ensemble of six pairs of RCM experiments performed at 25 and 50 km for the period 1961-2000 over a large European domain is examined in order to evaluate the effects of resolution on the simulation of daily precipitation statistics. Application of the non-parametric two-sample Kolmorgorov-Smirnov test, which tests for differences in the location and shape of the probability distributions of two samples, shows that the distribution of daily precipitation differs between the pairs of simulations over most land areas in both summer and winter, with the strongest signal over southern Europe. Two-dimensional histograms reveal that precipitation intensity increases with resolution over almost the entire domain in both winter and summer. In addition, the 25 km simulations have more dry days than the 50 km simulations. The increase in dry days with resolution is indicative of an improvement in model performance at higher resolution, while the more intense precipitation exceeds observed values. The systematic increase in precipitation extremes with resolution across all models suggests that this response is fundamental to model formulation. Simple theoretical arguments suggest that fluid continuity, combined with the emergent scaling properties of the horizontal wind field, results in an increase in resolved vertical transport as grid spacing decreases. This increase in resolution-dependent vertical mass flux then drives an intensification of convergence and resolvable-scale precipitation as grid spacing decreases. This theoretical result could help explain the increasingly, and often anomalously, large stratiform contribution to total rainfall observed with increasing resolution in many regional and global models.

  13. Conflict Management Strategies in the ICU Differ Between Palliative Care Specialists and Intensivists.

    PubMed

    Chiarchiaro, Jared; White, Douglas B; Ernecoff, Natalie C; Buddadhumaruk, Praewpannarai; Schuster, Rachel A; Arnold, Robert M

    2016-05-01

    Conflict is common between physicians and surrogate decision makers around end-of-life care in ICU. Involving experts in conflict management improve outcomes, but little is known about what differences in conflict management styles may explain the benefit. We used simulation to examine potential differences in how palliative care specialists manage conflict with surrogates about end-of-life treatment decisions in ICUs compared with intensivists. Subjects participated in a high-fidelity simulation of conflict with a surrogate in an ICU. In this simulation, a medical actor portrayed a surrogate decision maker during an ICU family meeting who refuses to follow an advance directive that clearly declines advanced life-sustaining therapies. We audiorecorded the simulation encounters and applied a coding framework to quantify conflict management behaviors, which was organized into two categories: task-focused communication and relationship building. We used negative binomial modeling to determine whether there were differences between palliative care specialists' and intensivists' use of task-focused communication and relationship building. Single academic medical center ICU. Palliative care specialists and intensivists. None. We enrolled 11 palliative care specialists and 25 intensivists. The palliative care specialists were all attending physicians. The intensivist group consisted of 11 attending physicians, 9 pulmonary and critical care fellows, and 5 internal medicine residents rotating in the ICU. We excluded five residents from the primary analysis in order to reduce confounding due to training level. Physicians' mean age was 37 years with a mean of 8 years in practice. Palliative care specialists used 55% fewer task-focused communication statements (incidence rate ratio, 0.55; 95% CI, 0.36-0.83; p = 0.005) and 48% more relationship-building statements (incidence rate ratio, 1.48; 95% CI, 0.89-2.46; p = 0.13) compared with intensivists. We found that palliative care specialists engage in less task-focused communication when managing conflict with surrogates compared with intensivists. These differences may help explain the benefit of palliative care involvement in conflict and could be the focus of interventions to improve clinicians' conflict resolution skills.

  14. Conflict Management Strategies in the ICU Differ Between Palliative Care Specialists and Intensivists

    PubMed Central

    Chiarchiaro, Jared; White, Douglas B.; Ernecoff, Natalie C.; Buddadhumaruk, Praewpannarai; Schuster, Rachel A.; Arnold, Robert M.

    2016-01-01

    OBJECTIVE Conflict is common between physicians and surrogate decision makers around end-of-life care in intensive care units (ICU). Involving experts in conflict management improve outcomes, but little is known about what differences in conflict management styles may explain the benefit. We used simulation to examine potential differences in how palliative care specialists manage conflict with surrogates about end-of-life treatment decisions in ICUs compared with intensivists. DESIGN Subjects participated in a high-fidelity simulation of conflict with a surrogate in an ICU. In this simulation, a medical actor portrayed a surrogate decision maker during an ICU family meeting who refuses to follow an advance directive that clearly declines advanced life-sustaining therapies. We audio-recorded the simulation encounters and applied a coding framework to quantify conflict management behaviors, which was organized into two categories: task-focused communication and relationship-building. We used negative binomial modeling to determine whether there were differences between palliative care specialists’ and intensivists’ use of task-focused communication and relationship building. SETTING Single academic medical center ICU PARTICIPANTS Palliative care specialists and intensivists INTERVENTIONS none MEASUREMENTS and MAIN RESULTS We enrolled 11 palliative care specialists and 25 intensivists. The palliative care specialists were all attending physicians. The intensivist group consisted of 11 attending physicians, 9 pulmonary and critical care fellows, and 5 internal medicine residents rotating in the intensive care unit. We excluded the 5 residents from the primary analysis in order to reduce confounding due to training level. Physicians’ mean age was 37 years with a mean of 8 years in practice. Palliative care specialists used 55% fewer task-focused communication statements (Incidence Rate Ratio 0.55, 95% CI 0.36–0.83, p= 0.005) and 48% more relationship building statements (Incidence Rate Ratio 1.48, 95% CI 0.89–2.46, p=0.13) compared with intensivists. CONCLUSIONS We found that palliative care specialists engage in less task-focused communication when managing conflict with surrogates compared to intensivists. These differences may help explain the benefit of palliative care involvement in conflict and could be the focus of interventions to improve clinicians’ conflict resolution skills. PMID:26765500

  15. Decisions on control of foot-and-mouth disease informed using model predictions.

    PubMed

    Halasa, T; Willeberg, P; Christiansen, L E; Boklund, A; Alkhamis, M; Perez, A; Enøe, C

    2013-11-01

    The decision on whether or not to change the control strategy, such as introducing emergency vaccination, is perhaps one of the most difficult decisions faced by the veterinary authorities during a foot-and-mouth disease (FMD) epidemic. A simple tool that may predict the epidemic outcome and consequences would be useful to assist the veterinary authorities in the decision-making process. A previously proposed simple quantitative tool based on the first 14 days outbreaks (FFO) of FMD was used with results from an FMD simulation exercise. Epidemic outcomes included the number of affected herds, epidemic duration, geographical size and costs. The first 14 days spatial spread (FFS) was also included to further support the prediction. The epidemic data was obtained from a Danish version (DTU-DADS) of a pre-existing FMD simulation model (Davis Animal Disease Spread - DADS) adapted to model the spread of FMD in Denmark. The European Union (EU) and Danish regulations for FMD control were used in the simulation. The correlations between FFO and FFS and the additional number of affected herds after day 14 following detection of the first infected herd were 0.66 and 0.82, respectively. The variation explained by the FFO at day 14 following detection was high (P-value<0.001). This indicates that the FFO may take a part in the decision of whether or not to intensify FMD control, for instance by introducing emergency vaccination and/or pre-emptive depopulation, which might prevent a "catastrophic situation". A significant part of the variation was explained by supplementing the model with the FFS (P-value<0.001). Furthermore, the type of the index-herd was also a significant predictor of the epidemic outcomes (P-value<0.05). The results of the current study suggest that national veterinary authorities should consider to model their national situation and to use FFO and FFS to help planning and updating their contingency plans and FMD emergency control strategies. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Agent-based and phylogenetic analyses reveal how HIV-1 moves between risk groups: injecting drug users sustain the heterosexual epidemic in Latvia

    PubMed Central

    Graw, Frederik; Leitner, Thomas; Ribeiro, Ruy M.

    2012-01-01

    Injecting drug users (IDU) are a driving force for the spread of HIV-1 in Latvia and other Baltic States, accounting for a majority of cases. However, in recent years, heterosexual cases have increased disproportionately. It is unclear how the changes in incidence patterns in Latvia can be explained, and how important IDU are for the heterosexual sub-epidemic. We introduce a novel epidemic model and use phylogenetic analyses in parallel to examine the spread of HIV-1 in Latvia between 1987 and 2010. Using a hybrid framework with a mean-field description for the susceptible population and an agent-based model for the infecteds, we track infected individuals and follow transmission histories dynamically formed during the simulation. The agent-based simulations and the phylogenetic analysis show that more than half of the heterosexual transmissions in Latvia were caused by IDU, which sustain the heterosexual epidemic. Indeed, we find that heterosexual clusters are characterized by short transmission chains with up to 63% of the chains dying out after the first introduction. In the simulations, the distribution of transmission chain sizes follows a power law distribution, which is confirmed by the phylogenetic data. Our models indicate that frequent introductions reduced the extinction probability of an autonomously spreading heterosexual HIV-1 epidemic, which now has the potential to dominate the spread of the overall epidemic in the future. Furthermore, our model shows that social heterogeneity of the susceptible population can explain the shift in HIV-1 incidence in Latvia over the course of the epidemic. Thus, the decrease in IDU incidence may be due to local heterogeneities in transmission, rather than the implementation of control measures. Increases in susceptibles, through social or geographic movement of IDU, could lead to a boost in HIV-1 infections in this risk group. Targeting individuals that bridge social groups would help prevent further spread of the epidemic. PMID:22664069

  17. Agent-based and phylogenetic analyses reveal how HIV-1 moves between risk groups: injecting drug users sustain the heterosexual epidemic in Latvia.

    PubMed

    Graw, Frederik; Leitner, Thomas; Ribeiro, Ruy M

    2012-06-01

    Injecting drug users (IDUs) are a driving force for the spread of HIV-1 in Latvia and other Baltic States, accounting for a majority of cases. However, in recent years, heterosexual cases have increased disproportionately. It is unclear how the changes in incidence patterns in Latvia can be explained, and how important IDUs are for the heterosexual sub-epidemic. We introduce a novel epidemic model and use phylogenetic analyses in parallel to examine the spread of HIV-1 in Latvia between 1987 and 2010. Using a hybrid framework with a mean-field description for the susceptible population and an agent-based model for the infecteds, we track infected individuals and follow transmission histories dynamically formed during the simulation. The agent-based simulations and the phylogenetic analysis show that more than half of the heterosexual transmissions in Latvia were caused by IDU, which sustain the heterosexual epidemic. Indeed, we find that heterosexual clusters are characterized by short transmission chains with up to 63% of the chains dying out after the first introduction. In the simulations, the distribution of transmission chain sizes follows a power law distribution, which is confirmed by the phylogenetic data. Our models indicate that frequent introductions reduced the extinction probability of an autonomously spreading heterosexual HIV-1 epidemic, which now has the potential to dominate the spread of the overall epidemic in the future. Furthermore, our model shows that social heterogeneity of the susceptible population can explain the shift in HIV-1 incidence in Latvia over the course of the epidemic. Thus, the decrease in IDU incidence may be due to local heterogeneities in transmission, rather than the implementation of control measures. Increases in susceptibles, through social or geographic movement of IDU, could lead to a boost in HIV-1 infections in this risk group. Targeting individuals that bridge social groups would help prevent further spread of the epidemic. Copyright © 2012 Elsevier B.V. All rights reserved.

  18. Using Computer Simulations in Drug Education Lessons.

    ERIC Educational Resources Information Center

    Bentz, Glenda D.

    1989-01-01

    Discussion of drug education for fifth grade students focuses on a computer simulation in which students role-play adolescents encountering various situations where there is drug or alcohol involvement. Activities in the simulation are explained, and discussion groups that occur following the simulation are described. (LRW)

  19. The New England Climate Adaptation Project: Enhancing Local Readiness to Adapt to Climate Change through Role-Play Simulations

    NASA Astrophysics Data System (ADS)

    Rumore, D.; Kirshen, P. H.; Susskind, L.

    2014-12-01

    Despite scientific consensus that the climate is changing, local efforts to prepare for and manage climate change risks remain limited. How we can raise concern about climate change risks and enhance local readiness to adapt to climate change's effects? In this presentation, we will share the lessons learned from the New England Climate Adaptation Project (NECAP), a participatory action research project that tested science-based role-play simulations as a tool for educating the public about climate change risks and simulating collective risk management efforts. NECAP was a 2-year effort involving the Massachusetts Institute of Technology, the Consensus Building Institute, the National Estuarine Research Reserve System, and four coastal New England municipalities. During 2012-2013, the NECAP team produced downscaled climate change projections, a summary risk assessment, and a stakeholder assessment for each partner community. Working with local partners, we used these assessments to create a tailored, science-based role-play simulation for each site. Through a series of workshops in 2013, NECAP engaged between 115-170 diverse stakeholders and members of the public in each partner municipality in playing the simulation and a follow up conversation about local climate change risks and possible adaptation strategies. Data were collected through before-and-after surveys administered to all workshop participants, follow-up interviews with 25 percent of workshop participants, public opinion polls conducted before and after our intervention, and meetings with public officials. This presentation will report our research findings and explain how science-based role-play simulations can be used to help communicate local climate change risks and enhance local readiness to adapt.

  20. Diagnostic Hypothesis Generation and Human Judgment

    ERIC Educational Resources Information Center

    Thomas, Rick P.; Dougherty, Michael R.; Sprenger, Amber M.; Harbison, J. Isaiah

    2008-01-01

    Diagnostic hypothesis-generation processes are ubiquitous in human reasoning. For example, clinicians generate disease hypotheses to explain symptoms and help guide treatment, auditors generate hypotheses for identifying sources of accounting errors, and laypeople generate hypotheses to explain patterns of information (i.e., data) in the…

  1. Topical Backgrounder: How Safe Am I? Helping Communities Evaluate Chemical Risks

    EPA Pesticide Factsheets

    Part of the May 1999 Guides to Environmental Risk Management Series created by the National Safety Council. Explains how RMPs will help prevent emergency chemical releases, reduce risk from exposure to hazards, and minimize consequences.

  2. Numerical analyses of evolution of unsteady flow structures in the wake of flapping starling wing model

    NASA Astrophysics Data System (ADS)

    Krishnan, Krishnamoorthy; Naqavi, Iftekhar Z.; Gurka, Roi

    2017-11-01

    Understanding the physics of flapping wings at moderate Reynolds number flows takes on greater importance in the context of avian aerodynamics as well as in the design of miniature-aerial-vehicles. Analyzing the characteristics of wake vortices generated downstream of flapping wings can help to explain the unsteady contribution to the aerodynamics loads. In this study, numerical simulations of flow over a bio-inspired pseudo-2D flapping wing model was conducted to characterize the evolution of unsteady flow structures in the downstream wake of flapping wing. The wing model was based on a European starling's wing and wingbeat kinematics were incorporated to simulate a free-forward flight. The starling's wingbeat kinematics were extracted from experiments conducted in a wind tunnel where freely flying starling was measured using high-speed PIV as well as high-speed imaging yielding a series of kinematic images sampled at 500 Hz. The average chord of the wing section was 6 cm and simulations were carried out at a Reynolds number of 54,000, reduced frequency of 0.17, and Strouhal number of 0.16. Large eddy simulation was performed using a second order, finite difference code ParLES. Characteristics of wake vortex structures during the different phases of the wing strokes were examined. The role of wingbeat kinematics in the configuration of downstream vortex patterns is discussed. Evaluated wake topology and lift-drag characteristics are compared with the starling's wind tunnel results.

  3. The role of imagistic simulation in scientific thought experiments.

    PubMed

    Clement, John J

    2009-10-01

    Interest in thought experiments (TEs) derives from the paradox: "How can findings that carry conviction result from a new experiment conducted entirely within the head?" Historical studies have established the importance of TEs in science but have proposed disparate hypotheses concerning the source of knowledge in TEs, ranging from empiricist to rationalist accounts. This article analyzes TEs in think-aloud protocols of scientifically trained experts to examine more fine-grained information about their use. Some TEs appear powerful enough to discredit an existing theory-a disconfirmatory purpose. In addition, confirmatory and generative purposes were identified for other TEs. One can also use details in transcript data, including imagery reports and gestures, to provide evidence for a central role played by imagistic simulations in many TEs, and to suggest that these simulations can generate new knowledge using several sources, including the "extended application" of perceptual motor schemas, implicit prior knowledge, and spatial reasoning operations, in contrast to formal arguments. These sources suggest what it means for TEs to be grounded in embodied processes that can begin to explain the paradox above. This leads to a rationalistic view of TEs as using productive internal reasoning, but the view also acknowledges the historical role that experience with the world can play in forming certain schemas used in TEs. Understanding such processes could help provide a foundation for developing a larger model of scientific investigation processes grounded on imagistic simulation (Clement, 2008). Copyright © 2009 Cognitive Science Society, Inc.

  4. Muscle-tendon mechanics explain unexpected effects of exoskeleton assistance on metabolic rate during walking.

    PubMed

    Jackson, Rachel W; Dembia, Christopher L; Delp, Scott L; Collins, Steven H

    2017-06-01

    The goal of this study was to gain insight into how ankle exoskeletons affect the behavior of the plantarflexor muscles during walking. Using data from previous experiments, we performed electromyography-driven simulations of musculoskeletal dynamics to explore how changes in exoskeleton assistance affected plantarflexor muscle-tendon mechanics, particularly for the soleus. We used a model of muscle energy consumption to estimate individual muscle metabolic rate. As average exoskeleton torque was increased, while no net exoskeleton work was provided, a reduction in tendon recoil led to an increase in positive mechanical work performed by the soleus muscle fibers. As net exoskeleton work was increased, both soleus muscle fiber force and positive mechanical work decreased. Trends in the sum of the metabolic rates of the simulated muscles correlated well with trends in experimentally observed whole-body metabolic rate ( R 2 =0.9), providing confidence in our model estimates. Our simulation results suggest that different exoskeleton behaviors can alter the functioning of the muscles and tendons acting at the assisted joint. Furthermore, our results support the idea that the series tendon helps reduce positive work done by the muscle fibers by storing and returning energy elastically. We expect the results from this study to promote the use of electromyography-driven simulations to gain insight into the operation of muscle-tendon units and to guide the design and control of assistive devices. © 2017. Published by The Company of Biologists Ltd.

  5. Visible Near-infrared Spectral Evolution of Irradiated Mixed Ices and Application to Kuiper Belt Objects and Jupiter Trojans

    NASA Astrophysics Data System (ADS)

    Poston, Michael J.; Mahjoub, Ahmed; Ehlmann, Bethany L.; Blacksberg, Jordana; Brown, Michael E.; Carlson, Robert W.; Eiler, John M.; Hand, Kevin P.; Hodyss, Robert; Wong, Ian

    2018-04-01

    Understanding the history of Kuiper Belt Objects and Jupiter Trojans will help to constrain models of solar system formation and dynamical evolution. Laboratory simulations of a possible thermal and irradiation history of these bodies were conducted on ice mixtures while monitoring their spectral properties. These simulations tested the hypothesis that the presence or absence of sulfur explains the two distinct visible near-infrared spectral groups observed in each population and that Trojans and KBOs share a common formation location. Mixed ices consisting of water, methanol, and ammonia, in mixtures both with and without hydrogen sulfide, were deposited and irradiated with 10 keV electrons. Deposition and initial irradiation were performed at 50 K to simulate formation at 20 au in the early solar system, then heated to Trojan-like temperatures and irradiated further. Finally, irradiation was concluded and resulting samples were observed during heating to room temperature. Results indicated that the presence of sulfur resulted in steeper spectral slopes. Heating through the 140–200 K range decreased the slopes and total reflectance for both mixtures. In addition, absorption features at 410, 620, and 900 nm appeared under irradiation, but only in the H2S-containing mixture. These features were lost with heating once irradiation was concluded. While the results reported here are consistent with the hypothesis, additional work is needed to address uncertainties and to simulate conditions not included in the present work.

  6. Design analysis and simulation study of an efficiency enhanced L-band MILO

    NASA Astrophysics Data System (ADS)

    Dixit, Gargi; Kumar, Arjun; Jain, P. K.

    2017-01-01

    In this article, an experimental L-band compact magnetically insulated transmission line oscillator (MILO) has been simulated using the 3D PIC simulation code "Particle Studio," and an improvement in the device efficiency has been obtained. The detailed interaction and operating mechanism describing the role of sub-assemblies have been explained. The performance of the device was found to be the function of the distance between the end-surface of the cathode and the beam-dump disk. During simulation, a high power microwave of the TM01 mode is generated with the peak RF-power of 6 GW and the power conversion efficiency of 19.2%, at the operating voltage of ˜600 kV and at the current of 52 kA. For better impedance matching or maximum power transfer, four stubs have been placed at the λg/4 distance from the extractor cavity, which results in the stable RF power output. In this work, an improved L-band MILO along with a new type beam-dump disk is selected for performance improvement with typical design parameters and beam parameters. The total peak power of improved MILO is 7 GW, and the maximum power conversion efficiency is 22.4%. This improvement is achieved due to the formation of the virtual cathode at the load side, which helps in modulating the energy of electrons owing to maximum reflection of electrons from the mesh or foil.

  7. Episodic simulation and episodic memory can increase intentions to help others.

    PubMed

    Gaesser, Brendan; Schacter, Daniel L

    2014-03-25

    Empathy plays an important role in human social interaction. A multifaceted construct, empathy includes a prosocial motivation or intention to help others in need. Although humans are often willing to help others in need, at times (e.g., during intergroup conflict), empathic responses are diminished or absent. Research examining the cognitive mechanisms underlying prosocial tendencies has focused on the facilitating roles of perspective taking and emotion sharing but has not previously elucidated the contributions of episodic simulation and memory to facilitating prosocial intentions. Here, we investigated whether humans' ability to construct episodes by vividly imagining (episodic simulation) or remembering (episodic memory) specific events also supports a willingness to help others. Three experiments provide evidence that, when participants were presented with a situation depicting another person's plight, the act of imagining an event of helping the person or remembering a related past event of helping others increased prosocial intentions to help the present person in need, compared with various control conditions. We also report evidence suggesting that the vividness of constructed episodes--rather than simply heightened emotional reactions or degree of perspective taking--supports this effect. Our results shed light on a role that episodic simulation and memory can play in fostering empathy and begin to offer insight into the underlying mechanisms.

  8. Developing a Problem-Based Learning Simulation: An Economics Unit on Trade

    ERIC Educational Resources Information Center

    Maxwell, Nan L.; Mergendoller, John R.; Bellisimo, Yolanda

    2004-01-01

    This article argues that the merger of simulations and problem-based learning (PBL) can enhance both active-learning strategies. Simulations benefit by using a PBL framework to promote student-directed learning and problem-solving skills to explain a simulated dilemma with multiple solutions. PBL benefits because simulations structure the…

  9. Practical and Creative Simulations for Training Personnel in Deafblindness.

    ERIC Educational Resources Information Center

    Olson, Joyce; Grondin, Jennifer

    This monograph describes how to conduct simulations that allow individuals to experience what it is like to have deafblindness. It begins by discussing the philosophy and benefits of simulations and explains the two different types of simulations. The first type of simulation gives a generic overview of the impact of deafblindness on learning and…

  10. Simulation Methodology in Nursing Education and Adult Learning Theory

    ERIC Educational Resources Information Center

    Rutherford-Hemming, Tonya

    2012-01-01

    Simulation is often used in nursing education as a teaching methodology. Simulation is rooted in adult learning theory. Three learning theories, cognitive, social, and constructivist, explain how learners gain knowledge with simulation experiences. This article takes an in-depth look at each of these three theories as each relates to simulation.…

  11. Helping Your Older Family Member Handle Finances. A Pacific Northwest Extension Publication. PNW 344.

    ERIC Educational Resources Information Center

    Schmall, Vicki L.; Nay, Tim

    This booklet is designed to help individuals help older family members handle their finances. Presented first are 10 guidelines for keeping the tension involved in intervening in an older relative's finances to a minimum. The following financial/legal instruments are explained: joint bank accounts, powers of attorney (including durable powers of…

  12. Visual perception and consciousness in dermatopathology: mechanisms of figure-ground segregation account for errors in diagnosis.

    PubMed

    Böer, Almut

    2009-02-01

    Visual perception has been the object of research in psychology for almost a century. Little has been written, however, about the effects of perceptive phenomena on methods in medicine that utilize interpretation of two-dimensional images for diagnosis. Starting from the work by Edgar Rubin in the beginning of the last century, this article gives a summary of observations of psychologists who investigated the mechanisms of so-called "figure-ground segregation." These unconscious mechanisms follow rules that explain why certain structures are perceived consciously as a figure, whereas other structures surrounding such a figure are neglected and not perceived consciously in detail. Perception of a structure as a figure can be due to, for example, a convex shape of its contour, proximity of lines around it, closed contours, a simple shape, and attribution of meaning to a structure. In examples from the practice of dermatopathology, those unconscious mechanisms of figure-ground segregation will be shown to be relevant to diagnosis of sections of tissue. The mechanisms help to explain why, for example, ill-defined and concave-shaped structures, stromal differences of neoplasms, interstitial infiltrates and deposits, and simulators of common diseases are often difficult to recognize at first sight. Teachers of dermatopathology need to be aware of these unconscious mechanisms of visual perception because they explain why novices struggle with certain diagnoses and differential diagnoses. Proper instruction about these phenomena, early in the process of training, will prevent a student from being frustrated with misperceptions.

  13. Discrete-Event Simulation in Chemical Engineering.

    ERIC Educational Resources Information Center

    Schultheisz, Daniel; Sommerfeld, Jude T.

    1988-01-01

    Gives examples, descriptions, and uses for various types of simulation systems, including the Flowtran, Process, Aspen Plus, Design II, GPSS, Simula, and Simscript. Explains similarities in simulators, terminology, and a batch chemical process. Tables and diagrams are included. (RT)

  14. From Large-scale to Protostellar Disk Fragmentation into Close Binary Stars

    NASA Astrophysics Data System (ADS)

    Sigalotti, Leonardo Di G.; Cruz, Fidel; Gabbasov, Ruslan; Klapp, Jaime; Ramírez-Velasquez, José

    2018-04-01

    Recent observations of young stellar systems with the Atacama Large Millimeter/submillimeter Array (ALMA) and the Karl G. Jansky Very Large Array are helping to cement the idea that close companion stars form via fragmentation of a gravitationally unstable disk around a protostar early in the star formation process. As the disk grows in mass, it eventually becomes gravitationally unstable and fragments, forming one or more new protostars in orbit with the first at mean separations of 100 au or even less. Here, we report direct numerical calculations down to scales as small as ∼0.1 au, using a consistent Smoothed Particle Hydrodynamics code, that show the large-scale fragmentation of a cloud core into two protostars accompanied by small-scale fragmentation of their circumstellar disks. Our results demonstrate the two dominant mechanisms of star formation, where the disk forming around a protostar (which in turn results from the large-scale fragmentation of the cloud core) undergoes eccentric (m = 1) fragmentation to produce a close binary. We generate two-dimensional emission maps and simulated ALMA 1.3 mm continuum images of the structure and fragmentation of the disks that can help explain the dynamical processes occurring within collapsing cloud cores.

  15. Algorithmic procedures for Bayesian MEG/EEG source reconstruction in SPM.

    PubMed

    López, J D; Litvak, V; Espinosa, J J; Friston, K; Barnes, G R

    2014-01-01

    The MEG/EEG inverse problem is ill-posed, giving different source reconstructions depending on the initial assumption sets. Parametric Empirical Bayes allows one to implement most popular MEG/EEG inversion schemes (Minimum Norm, LORETA, etc.) within the same generic Bayesian framework. It also provides a cost-function in terms of the variational Free energy-an approximation to the marginal likelihood or evidence of the solution. In this manuscript, we revisit the algorithm for MEG/EEG source reconstruction with a view to providing a didactic and practical guide. The aim is to promote and help standardise the development and consolidation of other schemes within the same framework. We describe the implementation in the Statistical Parametric Mapping (SPM) software package, carefully explaining each of its stages with the help of a simple simulated data example. We focus on the Multiple Sparse Priors (MSP) model, which we compare with the well-known Minimum Norm and LORETA models, using the negative variational Free energy for model comparison. The manuscript is accompanied by Matlab scripts to allow the reader to test and explore the underlying algorithm. © 2013. Published by Elsevier Inc. All rights reserved.

  16. Webcams as a tool for teaching in Optometry training

    NASA Astrophysics Data System (ADS)

    Gargallo, A.; Arines, J.

    2015-04-01

    Clinical Optometry lab training is devoted to develop the students skills needed in eye healthcare professional practice. Nevertheless, students always find difficulties in the management of some optometric instruments and in the understanding of the evaluation techniques. Moreover, teachers also have problems in explaining the eye evaluation tests or making demonstrations of instruments handling. In order to facilitate the learning process, webcams adapted to the optometric devices represent a helpful and useful tool. In this work we present the use of webcams in some of the most common clinical test in Optometry as ocular refraction, colour vision test, eye health evaluation with slip-lamp, retinoscopy, ophthalmoscopy and contact lens fitting. Our experience shows that with this simple approach we can do things easier: show the instrument handling to all the students at the same time; take pictures or videos of different eye health conditions or exploratory routines for posterior visualization with all the students; recreate visual experience of the patient during optometric exam; simulate colour vision pathologies; increase the interactions between students allowing them to help and correct each other; and also record the final routine exam in order to make possible its revision with the students.

  17. Colour for Behavioural Success.

    PubMed

    Dresp-Langley, Birgitta; Reeves, Adam

    2018-01-01

    Colour information not only helps sustain the survival of animal species by guiding sexual selection and foraging behaviour but also is an important factor in the cultural and technological development of our own species. This is illustrated by examples from the visual arts and from state-of-the-art imaging technology, where the strategic use of colour has become a powerful tool for guiding the planning and execution of interventional procedures. The functional role of colour information in terms of its potential benefits to behavioural success across the species is addressed in the introduction here to clarify why colour perception may have evolved to generate behavioural success. It is argued that evolutionary and environmental pressures influence not only colour trait production in the different species but also their ability to process and exploit colour information for goal-specific purposes. We then leap straight to the human primate with insight from current research on the facilitating role of colour cues on performance training with precision technology for image-guided surgical planning and intervention. It is shown that local colour cues in two-dimensional images generated by a surgical fisheye camera help individuals become more precise rapidly across a limited number of trial sets in simulator training for specific manual gestures with a tool. This facilitating effect of a local colour cue on performance evolution in a video-controlled simulator (pick-and-place) task can be explained in terms of colour-based figure-ground segregation facilitating attention to local image parts when more than two layers of subjective surface depth are present, as in all natural and surgical images.

  18. Colour for Behavioural Success

    PubMed Central

    Reeves, Adam

    2018-01-01

    Colour information not only helps sustain the survival of animal species by guiding sexual selection and foraging behaviour but also is an important factor in the cultural and technological development of our own species. This is illustrated by examples from the visual arts and from state-of-the-art imaging technology, where the strategic use of colour has become a powerful tool for guiding the planning and execution of interventional procedures. The functional role of colour information in terms of its potential benefits to behavioural success across the species is addressed in the introduction here to clarify why colour perception may have evolved to generate behavioural success. It is argued that evolutionary and environmental pressures influence not only colour trait production in the different species but also their ability to process and exploit colour information for goal-specific purposes. We then leap straight to the human primate with insight from current research on the facilitating role of colour cues on performance training with precision technology for image-guided surgical planning and intervention. It is shown that local colour cues in two-dimensional images generated by a surgical fisheye camera help individuals become more precise rapidly across a limited number of trial sets in simulator training for specific manual gestures with a tool. This facilitating effect of a local colour cue on performance evolution in a video-controlled simulator (pick-and-place) task can be explained in terms of colour-based figure-ground segregation facilitating attention to local image parts when more than two layers of subjective surface depth are present, as in all natural and surgical images. PMID:29770183

  19. Water-Energy-Food Nexus: Compelling Issues for Geophysical Research

    NASA Astrophysics Data System (ADS)

    Akhbari, M.; Grigg, N. S.; Waskom, R.

    2014-12-01

    The joint security of water, food, and energy systems is an urgent issue everywhere, and strong drivers of development and land use change, exacerbated by climate change, require new knowledge to achieve integrated solution using a nexus-based approach to assess inter-dependencies. Effective research-based decision support tools are essential to identify the major issues and interconnections to help in implementation of the nexus approach. The major needs are models and data to clearly and unambiguously present decision scenarios to local cooperative groups of farmers, electric energy generators and water officials for joint decisions. These can be developed by integrated models to link hydrology, land use, energy use, cropping simulation, and optimization with economic objectives and socio-physical constraints. The first step in modeling is to have a good conceptual model and then to get data. As the linking of models increases uncertainties, each one should be supplied with adequate data at suitable spatial and temporal resolutions. Most models are supplied with data by geophysical scientists, such as hydrologists, geologists, atmospheric scientists, soil scientists, and climatologists, among others. Outcomes of a recently-completed project to study the water-energy-food nexus will be explained to illuminate the model and data needs to inform future management actions across the nexus. The project included a workshop of experts from government, business, academia, and the non-profit sector who met to define and explain nexus interactions and needs. An example of the findings is that data inconsistencies among sectors create barriers to integrated planning. A nexus-based systems model is needed to outline sectoral inter-dependencies and identify data demands and gaps. Geophysical scientists can help to create this model and take leadership on designing data systems to facilitate sharing and enable integrated management.

  20. Moving stimuli are less effectively masked using traditional continuous flash suppression (CFS) compared to a moving Mondrian mask (MMM): a test case for feature-selective suppression and retinotopic adaptation.

    PubMed

    Moors, Pieter; Wagemans, Johan; de-Wit, Lee

    2014-01-01

    Continuous flash suppression (CFS) is a powerful interocular suppression technique, which is often described as an effective means to reliably suppress stimuli from visual awareness. Suppression through CFS has been assumed to depend upon a reduction in (retinotopically specific) neural adaptation caused by the continual updating of the contents of the visual input to one eye. In this study, we started from the observation that suppressing a moving stimulus through CFS appeared to be more effective when using a mask that was actually more prone to retinotopically specific neural adaptation, but in which the properties of the mask were more similar to those of the to-be-suppressed stimulus. In two experiments, we find that using a moving Mondrian mask (i.e., one that includes motion) is more effective in suppressing a moving stimulus than a regular CFS mask. The observed pattern of results cannot be explained by a simple simulation that computes the degree of retinotopically specific neural adaptation over time, suggesting that this kind of neural adaptation does not play a large role in predicting the differences between conditions in this context. We also find some evidence consistent with the idea that the most effective CFS mask is the one that matches the properties (speed) of the suppressed stimulus. These results question the general importance of retinotopically specific neural adaptation in CFS, and potentially help to explain an implicit trend in the literature to adapt one's CFS mask to match one's to-be-suppressed stimuli. Finally, the results should help to guide the methodological development of future research where continuous suppression of moving stimuli is desired.

  1. A video to improve patient and surrogate understanding of cardiopulmonary resuscitation choices in the ICU: a randomized controlled trial.

    PubMed

    Wilson, Michael E; Krupa, Artur; Hinds, Richard F; Litell, John M; Swetz, Keith M; Akhoundi, Abbasali; Kashyap, Rahul; Gajic, Ognjen; Kashani, Kianoush

    2015-03-01

    To determine if a video depicting cardiopulmonary resuscitation and resuscitation preference options would improve knowledge and decision making among patients and surrogates in the ICU. Randomized, unblinded trial. Single medical ICU. Patients and surrogate decision makers in the ICU. The usual care group received a standard pamphlet about cardiopulmonary resuscitation and cardiopulmonary resuscitation preference options plus routine code status discussions with clinicians. The video group received usual care plus an 8-minute video that depicted cardiopulmonary resuscitation, showed a simulated hospital code, and explained resuscitation preference options. One hundred three patients and surrogates were randomized to usual care. One hundred five patients and surrogates were randomized to video plus usual care. Median total knowledge scores (0-15 points possible for correct answers) in the video group were 13 compared with 10 in the usual care group, p value of less than 0.0001. Video group participants had higher rates of understanding the purpose of cardiopulmonary resuscitation and resuscitation options and terminology and could correctly name components of cardiopulmonary resuscitation. No statistically significant differences in documented resuscitation preferences following the interventions were found between the two groups, although the trial was underpowered to detect such differences. A majority of participants felt that the video was helpful in cardiopulmonary resuscitation decision making (98%) and would recommend the video to others (99%). A video depicting cardiopulmonary resuscitation and explaining resuscitation preference options was associated with improved knowledge of in-hospital cardiopulmonary resuscitation options and cardiopulmonary resuscitation terminology among patients and surrogate decision makers in the ICU, compared with receiving a pamphlet on cardiopulmonary resuscitation. Patients and surrogates found the video helpful in decision making and would recommend the video to others.

  2. Comparison of fabric skins for the simulation of sweating on thermal manikins

    NASA Astrophysics Data System (ADS)

    Koelblen, Barbara; Psikuta, Agnes; Bogdan, Anna; Annaheim, Simon; Rossi, René M.

    2017-09-01

    Sweating is an important thermoregulatory process helping to dissipate heat and, thus, to prevent overheating of the human body. Simulations of human thermo-physiological responses in hot conditions or during exercising are helpful for assessing heat stress; however, realistic sweating simulation and evaporative cooling is needed. To this end, thermal manikins dressed with a tight fabric skin can be used, and the properties of this skin should help human-like sweat evaporation simulation. Four fabrics, i.e., cotton with elastane, polyester, polyamide with elastane, and a skin provided by a manikin manufacturer (Thermetrics) were compared in this study. The moisture management properties of the fabrics have been investigated in basic tests with regard to all phases of sweating relevant for simulating human thermo-physiological responses, namely, onset of sweating, fully developed sweating, and drying. The suitability of the fabrics for standard tests, such as clothing evaporative resistance measurements, was evaluated based on tests corresponding to the middle phase of sweating. Simulations with a head manikin coupled to a thermo-physiological model were performed to evaluate the overall performance of the skins. The results of the study showed that three out of four evaluated fabrics have adequate moisture management properties with regard to the simulation of sweating, which was confirmed in the coupled simulation with the head manikin. The presented tests are helpful for comparing the efficiency of different fabrics to simulate sweat-induced evaporative cooling on thermal manikins.

  3. Counseling Groups for African American Women: A Focus on Spirituality.

    ERIC Educational Resources Information Center

    Williams, Carmen Braun; Frame, Marsha Wiggins; Green, Evelyn

    1999-01-01

    Explains cultural and spiritual traditions within African American women's experience that form the foundation for group counseling strategies. Reviews literature regarding African American women's experience in groups. Explains group interventions such as art, music, dance, imagery, journaling, and rituals that can help transcend, empower, and…

  4. A comprehensive combined experimental and computational framework for pre-clinical wear simulation of total knee replacements.

    PubMed

    Abdelgaied, A; Fisher, J; Jennings, L M

    2018-02-01

    A more robust pre-clinical wear simulation framework is required in order to simulate wider and higher ranges of activities, observed in different patient populations such as younger more active patients. Such a framework will help to understand and address the reported higher failure rates for younger and more active patients (National_Joint_Registry, 2016). The current study has developed and validated a comprehensive combined experimental and computational framework for pre-clinical wear simulation of total knee replacements (TKR). The input mechanical (elastic modulus and Poisson's ratio) and wear parameters of the moderately cross-linked ultra-high molecular weight polyethylene (UHMWPE) bearing material were independently measured from experimental studies under realistic test conditions, similar to the loading conditions found in the total knee replacements. The wear predictions from the computational wear simulation were validated against the direct experimental wear measurements for size 3 Sigma curved total knee replacements (DePuy, UK) in an independent experimental wear simulation study under three different daily activities; walking, deep squat, and stairs ascending kinematic conditions. The measured compressive mechanical properties of the moderately cross-linked UHMWPE material were more than 20% lower than that reported in the literature under tensile test conditions. The pin-on-plate wear coefficient of moderately cross-linked UHMWPE was significantly dependant of the contact stress and the degree of cross-shear at the articulating surfaces. The computational wear predictions for the TKR from the current framework were consistent and in a good agreement with the independent full TKR experimental wear simulation measurements, with 0.94 coefficient of determination of the framework. In addition, the comprehensive combined experimental and computational framework was able to explain the complex experimental wear trends from the three different daily activities investigated. Therefore, such a framework can be adopted as a pre-clinical simulation approach to optimise different designs, materials, as well as patient's specific total knee replacements for a range of activities. Copyright © 2017. Published by Elsevier Ltd.

  5. Games Children Play: How Games and Sport Help Children Develop.

    ERIC Educational Resources Information Center

    Brooking-Payne, Kim

    This book presents games for children, teenagers, and adults, explaining how each game can help children develop in a holistic way. It begins by discussing tips for teaching games, how to deal with children who break the rules, and what type of equipment to use. The book provides help on how to approach play within each of the different age…

  6. Kennedy Space Center ITC-1 Internship Overview

    NASA Technical Reports Server (NTRS)

    Ni, Marcus

    2011-01-01

    As an intern for Priscilla Elfrey in the ITC-1 department, I was involved in many activities that have helped me to develop many new skills. I supported four different projects during my internship, which included the Center for Life Cycle Design (CfLCD), SISO Space Interoperability Smackdown, RTI Teacher Mentor Program, and the Discrete Event Simulation Integrated Visualization Environment Team (DIVE). I provided the CfLCD with web based research on cyber security initiatives involving simulation, education for young children, cloud computing, Otronicon, and Science, Technology, Engineering, and Mathematics (STEM) education initiatives. I also attended STEM meetings regarding simulation courses, and educational course enhancements. To further improve the SISO Simulation event, I provided observation feedback to the technical advisory board. I also helped to set up a chat federation for HLA. The third project involved the RTI Teacher Mentor program, which I helped to organize. Last, but not least, I worked with the DIVE team to develop new software to help visualize discrete event simulations. All of these projects have provided experience on an interdisciplinary level ranging from speech and communication to solving complex problems using math and science.

  7. Not Exactly Rocket Science.

    ERIC Educational Resources Information Center

    Barbian, Jeff

    2001-01-01

    Explains how low-tech experiential methods thrive in companies interested in fostering the human touch. Examples include NASA's paper airplane simulation, total immersion simulation, and fantasy multisensory environments. (JOW)

  8. Using Ratio Analysis to Evaluate Financial Performance.

    ERIC Educational Resources Information Center

    Minter, John; And Others

    1982-01-01

    The ways in which ratio analysis can help in long-range planning, budgeting, and asset management to strengthen financial performance and help avoid financial difficulties are explained. Types of ratios considered include balance sheet ratios, net operating ratios, and contribution and demand ratios. (MSE)

  9. Helping effort increases with relatedness in bell miners, but ‘unrelated’ helpers of both sexes still provide substantial care

    PubMed Central

    Wright, Jonathan; McDonald, Paul G.; te Marvelde, Luc; Kazem, Anahita J. N.; Bishop, Charles M.

    2010-01-01

    Indirect fitness benefits from kin selection can explain why non-breeding individuals help raise the young of relatives. However, the evolution of helping by non-relatives requires direct fitness benefits, for example via group augmentation. Here, we examine nest visit rates, load sizes and prey types delivered by breeding pairs and their helpers in the cooperatively breeding bell miner (Manorina melanophrys). In this system, males remain in their natal colony while young females typically disperse, and helpers of both sexes often assist at multiple nests concurrently. We found extremely clear evidence for the expected effect of genetic relatedness on individual helping effort per nest within colonies. This positive incremental effect of kinship was facultative—i.e. largely the result of within-individual variation in helping effort. Surprisingly, no sex differences were detectable in any aspect of helping, and even non-relatives provided substantial aid. Helpers and breeders of both sexes regulated their provisioning effort by responding visit-by-visit to changes in nestling begging. Helping behaviour in bell miners therefore appears consistent with adaptive cooperative investment in the brood, and kin-selected care by relatives. Similar investment by ‘unrelated’ helpers of both sexes argues against direct fitness benefits, but is perhaps explained by kin selection at the colony level. PMID:19846458

  10. You and I can see and help explain beautiful lights in the funny space air

    NASA Astrophysics Data System (ADS)

    MacDonald, E.

    2016-12-01

    Did you know there is exciting air and lights in space? The lights happen a little more every 11 years give or take. We are not sure how this happens. There is a lot we don't know about the air, the sun, and the space between. My job is to build stuff that flies in this funny air and then try to explain it better. This is important because the funny space air can make our space houses and other stuff break. My job number two is to help people see these cool lights in space using the phones in our pockets. They are so beautiful and we can explain them better working together. I hope you get to see these funny green and red lights in space!

  11. The Role of Influenza in the Delay between Low Temperature and Ischemic Heart Disease: Evidence from Simulation and Mortality Data from Japan

    PubMed Central

    Imai, Chisato; Barnett, Adrian G.; Hashizume, Masahiro; Honda, Yasushi

    2016-01-01

    Many studies have found that cardiovascular deaths mostly occur within a few days of exposure to heat, whereas cold-related deaths can occur up to 30 days after exposure. We investigated whether influenza infection could explain the delayed cold effects on ischemic heart diseases (IHD) as they can trigger IHD. We hypothesized two pathways between cold exposure and IHD: a direct pathway and an indirect pathway through influenza infection. We created a multi-state model of the pathways and simulated incidence data to examine the observed delayed patterns in cases. We conducted cross-correlation and time series analysis with Japanese daily pneumonia and influenza (P&I) mortality data to help validate our model. Simulations showed the IHD incidence through the direct pathway occurred mostly within 10 days, while IHD through influenza infection peaked at 4–6 days, followed by delayed incidences of up to 20–30 days. In the mortality data from Japan, P&I lagged IHD in cross-correlations. Time series analysis showed strong delayed cold effects in the older population. There was also a strong delay on intense days of influenza which was more noticeable in the older population. Influenza can therefore be a plausible explanation for the delayed association between cold exposure and cardiovascular mortality. PMID:27136571

  12. Molecular dynamics growth modeling of InAs1-xSbx-based type-II superlattice

    NASA Astrophysics Data System (ADS)

    Ciani, Anthony J.; Grein, Christoph H.; Irick, Barry; Miao, Maosheng; Kioussis, Nicholas

    2017-09-01

    Type-II strained-layer superlattices (T2SL) based on InAs1-xSbx are a promising photovoltaic detector material technology for thermal imaging; however, Shockley-Read-Hall recombination and generation rates are still too high for thermal imagers based on InAs1-xSbx T2SL to reach their ideal performance. Molecular dynamics simulations using the Stillinger-Weber (SW) empirical potentials are a useful tool to study the growth of tetrahedral coordinated crystals and the nonequilibrium formation of defects within them, including the long-range effects of strain. SW potentials for the possible atomic interactions among {Ga, In, As, Sb} were developed by fitting to ab initio calculations of elastically distorted zinc blende and diamond unit cells. The SW potentials were tested against experimental observations of molecular beam epitaxial (MBE) growth and then used to simulate the MBE growth of InAs/InAs0.5Sb0.5 T2SL on GaSb substrates over a range of processes parameters. The simulations showed and helped to explain Sb cross-incorporation into the InAs T2SL layers, Sb segregation within the InAsSb layers, and identified medium-range defect clusters involving interstitials and their induction of interstitial-vacancy pairs. Defect formation was also found to be affected by growth temperature and flux stoichiometry.

  13. Causes and implications of the growing divergence between climate model simulations and observations

    NASA Astrophysics Data System (ADS)

    Curry, Judith

    2014-03-01

    For the past 15+ years, there has been no increase in global average surface temperature, which has been referred to as a 'hiatus' in global warming. By contrast, estimates of expected warming in the first several decades of 21st century made by the IPCC AR4 were 0.2C/decade. This talk summarizes the recent CMIP5 climate model simulation results and comparisons with observational data. The most recent climate model simulations used in the AR5 indicate that the warming stagnation since 1998 is no longer consistent with model projections even at the 2% confidence level. Potential causes for the model-observation discrepancies are discussed. A particular focus of the talk is the role of multi-decadal natural internal variability on the climate variability of the 20th and early 21st centuries. The ``stadium wave'' climate signal is described, which propagates across the Northern Hemisphere through a network of ocean, ice, and atmospheric circulation regimes that self-organize into a collective tempo. The stadium wave hypothesis provides a plausible explanation for the hiatus in warming and helps explain why climate models did not predict this hiatus. Further, the new hypothesis suggests how long the hiatus might last. Implications of the hiatus are discussed in context of climate model sensitivity to CO2 forcing and attribution of the warming that was observed in the last quarter of the 20th century.

  14. SynBioSS designer: a web-based tool for the automated generation of kinetic models for synthetic biological constructs

    PubMed Central

    Weeding, Emma; Houle, Jason

    2010-01-01

    Modeling tools can play an important role in synthetic biology the same way modeling helps in other engineering disciplines: simulations can quickly probe mechanisms and provide a clear picture of how different components influence the behavior of the whole. We present a brief review of available tools and present SynBioSS Designer. The Synthetic Biology Software Suite (SynBioSS) is used for the generation, storing, retrieval and quantitative simulation of synthetic biological networks. SynBioSS consists of three distinct components: the Desktop Simulator, the Wiki, and the Designer. SynBioSS Designer takes as input molecular parts involved in gene expression and regulation (e.g. promoters, transcription factors, ribosome binding sites, etc.), and automatically generates complete networks of reactions that represent transcription, translation, regulation, induction and degradation of those parts. Effectively, Designer uses DNA sequences as input and generates networks of biomolecular reactions as output. In this paper we describe how Designer uses universal principles of molecular biology to generate models of any arbitrary synthetic biological system. These models are useful as they explain biological phenotypic complexity in mechanistic terms. In turn, such mechanistic explanations can assist in designing synthetic biological systems. We also discuss, giving practical guidance to users, how Designer interfaces with the Registry of Standard Biological Parts, the de facto compendium of parts used in synthetic biology applications. PMID:20639523

  15. Protonation-modulated localization of excess electrons in histidine aqueous solutions revealed by ab initio molecular dynamics simulations: anion-centered versus cation-centered localization.

    PubMed

    Gao, Liang; Bu, Yuxiang

    2017-05-31

    In this work, we present an ab initio molecular dynamics simulation study on the interaction of an excess electron (EE) with histidine in its aqueous solution. Two different configurations of histidine (imidazole group protonated or not) are considered to reflect its different existing forms in neutral or slightly acidic surroundings. The simulation results indicate that localizations of EEs in different aqueous histidine solutions are quite different and are strongly affected by protonation of the side chain imidazole group and are thus pH-controlled. In neutral aqueous histidine solution, an EE localizes onto the carboxyl anionic group of the amino acid backbone after a relatively lengthy diffuse state, performing just like in an aliphatic amino acid solution. But in weakly acidic solution in which the side chain imidazole group is protonated, an EE undergoes a short lifetime diffuse state and finally localizes on the protonated imidazole group. We carefully examine these two different localization dynamics processes and analyze the competition between different dominating groups in their corresponding electron localization mechanisms. To explain the difference, we investigate the frontier molecular orbitals of these two systems and find that their energy levels and compositions are important to determine these differences. These findings can provide helpful information to understand the interaction mechanisms of low energy EEs with amino acids and even oligopeptides, especially with aromatic rings.

  16. Labels, Gender-Role Conflict, Stigma, and Attitudes Toward Seeking Psychological Help in Men.

    PubMed

    Wahto, Rachel; Swift, Joshua K

    2016-05-01

    Despite a comparable need, research has indicated that on average men hold more negative attitudes toward psychological help seeking than women. Several researchers have suggested that the gender gap in service use and attitudes could be addressed through efforts to better market psychological services to men; however, a limited number of studies have tested this hypothesis. This study examined whether altering the labels for mental health providers (psychologist or counselor), settings (mental health clinic or counseling center), and treatments (problem or feeling focused) could result in less perceived stigma (social and self) by men. Participants, 165 male college students, were asked to read one of eight randomly assigned vignettes that described a man who was experiencing symptoms of depression and was considering seeking help. The vignettes differed in the labels that were used to describe the help that was being considered. Participants then completed measures assessing the stigma (self and social) associated with the treatment, and their preexisting experience of gender-role conflict and attitudes toward psychological help seeking. In summary, perceived stigma did not depend on the type of label that was used; however, 59% of the variance in attitudes was predicted by self-stigma (uniquely explaining 11%), gender-role conflict (uniquely explaining 10%), and social stigma (uniquely explaining 5%). Specifically, higher levels of gender-role conflict, social stigma, and self-stigma were associated with more negative attitudes toward psychological help seeking. Based on the demographics of the sample, these findings primarily have implications for Caucasian college-educated young adult men. Further limitations with the study and recommendations for future research are discussed. © The Author(s) 2014.

  17. A systems approach to healthcare: agent-based modeling, community mental health, and population well-being.

    PubMed

    Silverman, Barry G; Hanrahan, Nancy; Bharathy, Gnana; Gordon, Kim; Johnson, Dan

    2015-02-01

    Explore whether agent-based modeling and simulation can help healthcare administrators discover interventions that increase population wellness and quality of care while, simultaneously, decreasing costs. Since important dynamics often lie in the social determinants outside the health facilities that provide services, this study thus models the problem at three levels (individuals, organizations, and society). The study explores the utility of translating an existing (prize winning) software for modeling complex societal systems and agent's daily life activities (like a Sim City style of software), into a desired decision support system. A case study tests if the 3 levels of system modeling approach is feasible, valid, and useful. The case study involves an urban population with serious mental health and Philadelphia's Medicaid population (n=527,056), in particular. Section 3 explains the models using data from the case study and thereby establishes feasibility of the approach for modeling a real system. The models were trained and tuned using national epidemiologic datasets and various domain expert inputs. To avoid co-mingling of training and testing data, the simulations were then run and compared (Section 4.1) to an analysis of 250,000 Philadelphia patient hospital admissions for the year 2010 in terms of re-hospitalization rate, number of doctor visits, and days in hospital. Based on the Student t-test, deviations between simulated vs. real world outcomes are not statistically significant. Validity is thus established for the 2008-2010 timeframe. We computed models of various types of interventions that were ineffective as well as 4 categories of interventions (e.g., reduced per-nurse caseload, increased check-ins and stays, etc.) that result in improvement in well-being and cost. The 3 level approach appears to be useful to help health administrators sort through system complexities to find effective interventions at lower costs. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Investigation of post hydraulic fracturing well cleanup physics in the Cana Woodford Shale

    NASA Astrophysics Data System (ADS)

    Lu, Rong

    Hydraulic fracturing was first carried out in the 1940s and has gained popularity in current development of unconventional resources. Flowing back the fracturing fluids is critical to a frac job, and determining well cleanup characteristics using the flowback data can help improve frac design. It has become increasingly important as a result of the unique flowback profiles observed in some shale gas plays due to the unconventional formation characteristics. Computer simulation is an efficient and effective way to tackle the problem. History matching can help reveal some mechanisms existent in the cleanup process. The Fracturing, Acidizing, Stimulation Technology (FAST) Consortium at Colorado School of Mines previously developed a numerical model for investigating the hydraulic fracturing process, cleanup, and relevant physics. It is a three-dimensional, gas-water, coupled fracture propagation-fluid flow simulator, which has the capability to handle commonly present damage mechanisms. The overall goal of this research effort is to validate the model on real data and to investigate the dominant physics in well cleanup for the Cana Field, which produces from the Woodford Shale in Oklahoma. To achieve this goal, first the early time delayed gas production was explained and modeled, and a simulation framework was established that included all three relevant damage mechanisms for a slickwater fractured well. Next, a series of sensitivity analysis of well cleanup to major reservoir, fracture, and operational variables was conducted; five of the Cana wells' initial flowback data were history matched, specifically the first thirty days' gas and water producing rates. Reservoir matrix permeability, net pressure, Young's modulus, and formation pressure gradient were found to have an impact on the gas producing curve's shape, in different ways. Some moderately good matches were achieved, with the outcome of some unknown reservoir information being proposed using the corresponding inputs from the history matching study. It was also concluded that extended shut-in durations after fracturing all the stages do not delay production in the overall situation. The success of history matching will further knowledge of well cleanup characteristics in the Cana Field, enable the future usage of this tool in other hydraulically fractured gas wells, and help operators optimize the flowback operations. Future improvements can be achieved by further developing the current simulator so that it has the capability of optimizing its grids setting every time the user changes the inputs, which will result in better stability when the relative permeability setting is modified.

  19. The cathode plasma simulation

    NASA Astrophysics Data System (ADS)

    Suksila, Thada

    Since its invention at the University of Stuttgart, Germany in the mid-1960, scientists have been trying to understand and explain the mechanism of the plasma interaction inside the magnetoplasmadynamics (MPD) thruster. Because this thruster creates a larger level of efficiency than combustion thrusters, this MPD thruster is the primary cadidate thruster for a long duration (planetary) spacecraft. However, the complexity of this thruster make it difficult to fully understand the plasma interaction in an MPD thruster while operating the device. That is, there is a great deal of physics involved: the fluid dynamics, the electromagnetics, the plasma dynamics, and the thermodynamics. All of these physics must be included when an MPD thruster operates. In recent years, a computer simulation helped scientists to simulate the experiments by programing the physics theories and comparing the simulation results with the experimental data. Many MPD thruster simulations have been conducted: E. Niewood et al.[5], C. K. J. Hulston et al.[6], K. D. Goodfellow[3], J Rossignol et al.[7]. All of these MPD computer simulations helped the scientists to see how quickly the system responds to the new design parameters. For this work, a 1D MPD thruster simulation was developed to find the voltage drop between the cathode and the plasma regions. Also, the properties such as thermal conductivity, electrical conductivity and heat capacity are temperature and pressure dependent. These two conductivity and heat capacity are usually definded as constant values in many other models. However, this 1D and 2D cylindrical symmetry MPD thruster simulations include both temperature and pressure effects to the electrical, thermal conductivities and heat capacity values interpolated from W. F. Ahtye [4]. Eventhough, the pressure effect is also significant; however, in this study the pressure at 66 Pa was set as a baseline. The 1D MPD thruster simulation includes the sheath region, which is the interface between the plasma and the cathode regions. This sheath model [3] has been fully combined in the 1D simulation. That is, the sheath model calculates the heat flux and the sheath voltage by giving the temperature and the current density. This sheath model must be included in the simulation, as the sheath region is treated differently from the main plasma region. For our 2D cylindrical symmetry simulation, the dimensions of the cathode, the anode, the total current, the pressure, the type of gases, the work function can be changed in the input process as needed for particular interested. Also, the sheath model is still included and fully integrated in this 2D cylindrical symmetry simulation at the cathode surface grids. In addition, the focus of the 2D cylindrical symmetry simulation is to connect the properties on the plasma and the cathode regions on the cathode surface until the MPD thruster reach steady state and estimate the plasma arc attachement edge, electroarc edge, on the cathode surface. Finally, we can understand more about the behavior of an MPD thruster under many different conditions of 2D cylindrical symmetry MPD thruster simulations.

  20. Leakiness of Pinned Neighboring Surface Nanobubbles Induced by Strong Gas–Surface Interaction

    PubMed Central

    2018-01-01

    The stability of two neighboring surface nanobubbles on a chemically heterogeneous surface is studied by molecular dynamics (MD) simulations of binary mixtures consisting of Lennard-Jones (LJ) particles. A diffusion equation-based stability analysis suggests that two nanobubbles sitting next to each other remain stable, provided the contact line is pinned, and that their radii of curvature are equal. However, many experimental observations seem to suggest some long-term kind of ripening or shrinking of the surface nanobubbles. In our MD simulations we find that the growth/dissolution of the nanobubbles can occur due to the transfer of gas particles from one nanobubble to another along the solid substrate. That is, if the interaction between the gas and the solid is strong enough, the solid–liquid interface can allow for the existence of a “tunnel” which connects the liquid–gas interfaces of the two nanobubbles to destabilize the system. The crucial role of the gas–solid interaction energy is a nanoscopic element that hitherto has not been considered in any macroscopic theory of surface nanobubbles and may help to explain experimental observations of the long-term ripening. PMID:29438620

  1. Numerical simulation of formation and preservation of Ningwu ice cave, Shanxi, China

    NASA Astrophysics Data System (ADS)

    Yang, S.; Shi, Y.

    2015-04-01

    Ice caves exist in locations where annual average temperature in higher than 0 °C. An example is Ningwu ice cave, Shanxi Province, the largest ice cave in China. In order to quantitatively explain the mechanism of formation and preservation of the ice cave, we use Finite Element Method to simulate the heat transfer process at this ice cave. There are two major control factors. First, there is the seasonal asymmetric heat transfer. Heat is transferred into the ice cave from outside, very inefficiently by conduction in spring, summer and fall. In winter, thermal convection occurs that transfers heat very efficiently out of the ice cave, thus cooling it down. Secondly, ice-water phase change provides a heat barrier for heat transfer into the cave in summer. The calculation also helps to evaluate effects of global warming, tourists, etc. for sustainable development of ice cave as tourism resource. In some other ice caves in China, managers installed air-tight doors at these ice caves entrance intending to "protect" these caves, but this prevent cooling down these caves in winters and these cave ices will entirely melt within tens of years.

  2. Options for reducing food waste by quality-controlled logistics using intelligent packaging along the supply chain.

    PubMed

    Heising, Jenneke K; Claassen, G D H; Dekker, Matthijs

    2017-10-01

    Optimising supply chain management can help to reduce food waste. This paper describes how intelligent packaging can be used to reduce food waste when used in supply chain management based on quality-controlled logistics (QCL). Intelligent packaging senses compounds in the package that correlate with the critical quality attribute of a food product. The information on the quality of each individual packaged food item that is provided by the intelligent packaging can be used for QCL. In a conceptual approach it is explained that monitoring food quality by intelligent packaging sensors makes it possible to obtain information about the variation in the quality of foods and to use a dynamic expiration date (IP-DED) on a food package. The conceptual approach is supported by quantitative data from simulations on the effect of using the information of intelligent packaging in supply chain management with the goal to reduce food waste. This simulation shows that by using the information on the quality of products that is provided by intelligent packaging, QCL can substantially reduce food waste. When QCL is combined with dynamic pricing based on the predicted expiry dates, a further waste reduction is envisaged.

  3. The evaporatively driven cloud-top mixing layer

    NASA Astrophysics Data System (ADS)

    Mellado, Juan Pedro

    2010-11-01

    Turbulent mixing caused by the local evaporative cooling at the top cloud-boundary of stratocumuli will be discussed. This research is motivated by the lack of a complete understanding of several phenomena in that important region, which translates into an unacceptable variability of order one in current models, including those employed in climate research. The cloud-top mixing layer is a simplified surrogate to investigate, locally, particular aspects of the fluid dynamics at the boundary between the stratocumulus clouds and the upper cloud-free air. In this work, direct numerical simulations have been used to study latent heat effects. The problem is the following: When the cloud mixes with the upper cloud-free layer, relatively warm and dry, evaporation tends to cool the mixture and, if strong enough, the buoyancy reversal instability develops. This instability leads to a turbulent convection layer growing next to the upper boundary of the cloud, which is, in several aspects, similar to free convection below a cold horizontal surface. In particular, results show an approximately self-preserving behavior that is characterized by the molecular buoyancy flux at the inversion base, fact that helps to explain the difficulties found when doing large-eddy simulations of this problem using classical subgrid closures.

  4. Visualizing turbulent mixing of gases and particles

    NASA Technical Reports Server (NTRS)

    Ma, Kwan-Liu; Smith, Philip J.; Jain, Sandeep

    1995-01-01

    A physical model and interactive computer graphics techniques have been developed for the visualization of the basic physical process of stochastic dispersion and mixing from steady-state CFD calculations. The mixing of massless particles and inertial particles is visualized by transforming the vector field from a traditionally Eulerian reference frame into a Lagrangian reference frame. Groups of particles are traced through the vector field for the mean path as well as their statistical dispersion about the mean position by using added scalar information about the root mean square value of the vector field and its Lagrangian time scale. In this way, clouds of particles in a turbulent environment are traced, not just mean paths. In combustion simulations of many industrial processes, good mixing is required to achieve a sufficient degree of combustion efficiency. The ability to visualize this multiphase mixing can not only help identify poor mixing but also explain the mechanism for poor mixing. The information gained from the visualization can be used to improve the overall combustion efficiency in utility boilers or propulsion devices. We have used this technique to visualize steady-state simulations of the combustion performance in several furnace designs.

  5. On the dynamics of small-scale vorticity in isotropic turbulence

    NASA Technical Reports Server (NTRS)

    Jimenez, Javier; Wray, A. A.

    1994-01-01

    It was previously shown that the strong vorticity in isotropic turbulence is organized into tubular vortices ('worms') whose properties were characterized through the use of full numerical simulations at several Reynolds numbers. At the time most of the observations were kinematic, and several scaling laws were discovered for which there was no theoretical explanation. In the meantime, further analysis of the same fields yielded new information on the generation of the vortices, and it was realized that even if they had to be formed by stretching, they were at any given moment actually compressed at many points of their axes. This apparent contradiction was partially explained by postulating axial inertial waves induced by the nonuniformity of the vortex cores, which helped to 'spread' the axial strain and allowed the vortices to remain compact even if not uniformly stretched. The existence of such solutions was recently proved numerically. The present report discusses a set of new numerical simulations of isotropic turbulence, and a reanalysis of the old ones, in an effort to prove or disprove the presence of these waves in actual turbulent flows and to understand the dynamics, as opposed to the kinematics, of the vortices.

  6. DWARF GALAXIES AND THE COSMIC WEB

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Benitez-Llambay, Alejandro; Abadi, Mario G.; Navarro, Julio F.

    2013-02-01

    We use a cosmological simulation of the formation of the Local Group of Galaxies to identify a mechanism that enables the removal of baryons from low-mass halos without appealing to feedback or reionization. As the Local Group forms, matter bound to it develops a network of filaments and pancakes. This moving web of gas and dark matter drifts and sweeps a large volume, overtaking many halos in the process. The dark matter content of these halos is unaffected but their gas can be efficiently removed by ram pressure. The loss of gas is especially pronounced in low-mass halos due tomore » their lower binding energy and has a dramatic effect on the star formation history of affected systems. This 'cosmic web stripping' may help to explain the scarcity of dwarf galaxies compared with the numerous low-mass halos expected in {Lambda}CDM and the large diversity of star formation histories and morphologies characteristic of faint galaxies. Although our results are based on a single high-resolution simulation, it is likely that the hydrodynamical interaction of dwarf galaxies with the cosmic web is a crucial ingredient so far missing from galaxy formation models.« less

  7. Hypernetted-chain-like closure of Ornstein-Zernike equation in multibody dissipative particle dynamics

    NASA Astrophysics Data System (ADS)

    Mo, Chao-jie; Qin, Li-zi; Yang, Li-jun

    2017-10-01

    We have derived a hypernetted-chain-like (HNC-like) approximate closure of the Ornstein-Zernike equation for multibody dissipative particle dynamics (MDPD) system in which the classic closures are not directly practicable. We first point out that the Percus's method is applicable to MDPD system in which particles interact with a density-dependent potential. And then an HNC-like closure is derived using Percus's idea and the saddle-point approximation of particle free energy. This HNC-like closure is compared with results of previous researchers, and in many cases, it demonstrates better agreement with computer simulation results. The HNC-like closure is used to predict the cluster crystallization in MDPD. We determine whether the cluster crystallization will happen in a system utilizing the widely applicable Hansen-Verlet freezing criterion and by observing the radial distribution function. The conclusions drawn from the results of the HNC-like closure are in agreement with computer simulation results. We evaluate different weight functions to determine whether they are prone to cluster crystallization. A new effective density-dependent pairwise potential is also proposed to help to explain the tendency to cluster crystallization of MDPD systems.

  8. Using Metaphors to Explain Molecular Testing to Cancer Patients.

    PubMed

    Pinheiro, Ana P M; Pocock, Rachel H; Dixon, Margie D; Shaib, Walid L; Ramalingam, Suresh S; Pentz, Rebecca D

    2017-04-01

    Molecular testing to identify targetable molecular alterations is routine practice for several types of cancer. Explaining the underlying molecular concepts can be difficult, and metaphors historically have been used in medicine to provide a common language between physicians and patients. Although previous studies have highlighted the use and effectiveness of metaphors to help explain germline genetic concepts to the general public, this study is the first to describe the use of metaphors to explain molecular testing to cancer patients in the clinical setting. Oncologist-patient conversations about molecular testing were recorded, transcribed verbatim, and coded. If a metaphor was used, patients were asked to explain it and assess its helpfulness. Sixty-six patients participated. Nine oncologists used metaphors to describe molecular testing; 25 of 66 (38%) participants heard a metaphor, 13 of 25 (52%) were questioned, 11 of 13 (85%) demonstrated understanding and reported the metaphor as being useful. Seventeen metaphors (bus driver, boss, switch, battery, circuit, broken light switch, gas pedal, key turning off an engine, key opening a lock, food for growth, satellite and antenna, interstate, alternate circuit, traffic jam, blueprint, room names, Florida citrus) were used to explain eight molecular testing terms (driver mutations, targeted therapy, hormones, receptors, resistance, exon specificity, genes, and cancer signatures). Because metaphors have proven to be a useful communication tool in other settings, these 17 metaphors may be useful for oncologists to adapt to their own setting to explain molecular testing terms. The Oncologist 2017;22:445-449 Implications for Practice: This article provides a snapshot of 17 metaphors that proved useful in describing 8 complicated molecular testing terms at 3 sites. As complex tumor sequencing becomes standard of care in clinics and widely used in clinical research, the use of metaphors may prove a useful communication tool, as it has in other settings. Although this study had a small sample, almost all of the patients who were exposed to metaphors in explaining molecular testing reported it as being helpful to their understanding. These 17 metaphors are examples of potentially useful communication tools that oncologists can adapt to their own practice. © AlphaMed Press 2017.

  9. Automated Guidance for Thermodynamics Essays: Critiquing versus Revisiting

    ERIC Educational Resources Information Center

    Donnelly, Dermot F.; Vitale, Jonathan M.; Linn, Marcia C.

    2015-01-01

    Middle school students struggle to explain thermodynamics concepts. In this study, to help students succeed, we use a natural language processing program to analyze their essays explaining the aspects of thermodynamics and provide guidance based on the automated score. The 346 sixth-grade students were assigned to either the critique condition…

  10. Successful Inaugural Major Comprehensive Campaigns: How Organizational Learning Theory Helps Explain the Process

    ERIC Educational Resources Information Center

    Razafimanjato, Laza Johany

    2016-01-01

    This qualitative study consisted of two case studies of southern public metropolitan universities, which successfully completed inaugural major comprehensive fundraising campaigns. The purpose of the study was to explore how the process of initiating and competing an inaugural comprehensive fundraising campaign was explained by organizational…

  11. Examining Job Embeddedness Survey Items for an Adventure Education Population

    ERIC Educational Resources Information Center

    Wilson, Jackson

    2010-01-01

    Dysfunctional voluntary employee turnover is an issue that leads to major direct and indirect costs (e.g., Sagie, Birati, & Tziner, 2002). Although job satisfaction has classically been the predominant construct used to explain turnover, recently a new construct, job embeddedness, has been relatively successful at helping explain additional…

  12. Explaining Ramps with Models

    ERIC Educational Resources Information Center

    Campbell, Todd; Neilson, Drew

    2016-01-01

    In this article Campbell and Neilson discuss several design strategies developed or adopted that were found particularly helpful when sequencing a unit that focused on learning about motion and acceleration. Students were expected to predict, observe, and explain why a ball traveled down one ramp faster than the other. Before engaging students,…

  13. Managing Corporate Risk through Better Knowledge Management

    ERIC Educational Resources Information Center

    Neef, Dale

    2005-01-01

    Purpose: To explain how progressive companies are using a combination of knowledge and risk management (KRM) systems and techniques in order to help them to prevent, or respond most effectively to, ethical or reputation-damaging incidents. Design/methodology/approach: The paper explains KRM, develops a corporate integrity framework, and then…

  14. Numerical simulation model of hyperacute/acute stage white matter infarction.

    PubMed

    Sakai, Koji; Yamada, Kei; Oouchi, Hiroyuki; Nishimura, Tsunehiko

    2008-01-01

    Although previous studies have revealed the mechanisms of changes in diffusivity (apparent diffusion coefficient [ADC]) in acute brain infarction, changes in diffusion anisotropy (fractional anisotropy [FA]) in white matter have not been examined. We hypothesized that membrane permeability as well as axonal swelling play important roles, and we therefore constructed a simulation model using random walk simulation to replicate the diffusion of water molecules. We implemented a numerical diffusion simulation model of normal and infarcted human brains using C++ language. We constructed this 2-pool model using simple tubes aligned in a single direction. Random walk simulation diffused water. Axon diameters and membrane permeability were then altered in step-wise fashion. To estimate the effects of axonal swelling, axon diameters were changed from 6 to 10 microm. Membrane permeability was altered from 0% to 40%. Finally, both elements were combined to explain increasing FA in the hyperacute stage of white matter infarction. The simulation demonstrated that simple water shift into the intracellular space reduces ADC and increases FA, but not to the extent expected from actual human cases (ADC approximately 50%; FA approximately +20%). Similarly, membrane permeability alone was insufficient to explain this phenomenon. However, a combination of both factors successfully replicated changes in diffusivity indices. Both axonal swelling and reduced membrane permeability appear important in explaining changes in ADC and FA based on eigenvalues in hyperacute-stage white matter infarction.

  15. Moral imagination: Facilitating prosocial decision-making through scene imagery and theory of mind.

    PubMed

    Gaesser, Brendan; Keeler, Kerri; Young, Liane

    2018-02-01

    How we imagine and subjectively experience the future can inform how we make decisions in the present. Here, we examined a prosocial effect of imagining future episodes in motivating moral decisions about helping others in need, as well as the underlying cognitive mechanisms. Across three experiments we found that people are more willing to help others in specific situations after imagining helping them in those situations. Manipulating the spatial representation of imagined future episodes in particular was effective at increasing intentions to help others, suggesting that scene imagery plays an important role in the prosocial effect of episodic simulation. Path modeling analyses revealed that episodic simulation interacts with theory of mind in facilitating prosocial responses but can also operate independently. Moreover, we found that our manipulations of the imagined helping episode increased actual prosocial behavior, which also correlated with changes in reported willingness to help. Based on these findings, we propose a new model that begins to capture the multifaceted mechanisms by which episodic simulation contributes to prosocial decision-making, highlighting boundaries and promising future directions to explore. Implications for research in moral cognition, imagination, and patients with impairments in episodic simulation are discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Helping Them Grow.

    ERIC Educational Resources Information Center

    Brodkin, Adele M.; And Others

    1995-01-01

    Three articles discuss how to help elementary students grow. The first explains how teachers can weave a broader safety net for children with chaotic lives. The second presents year-end cooperative games for testing students' communication skills. The third offers take-home summer activities for parents and children. (SM)

  17. Erikson's Psychosocial Theories Help Explain Early Adolescence.

    ERIC Educational Resources Information Center

    Manning, M. Lee

    1988-01-01

    Middle school educators can design a learning environment for early adolescents based on Erik Erikson's social development theories, which divide human life into eight psychological stages. The identity versus role confusion stage characterizing adolescence will significantly determine the developing person's future. Schools can help learners…

  18. Grief: Helping Young Children Cope

    ERIC Educational Resources Information Center

    Wood, Frances B.

    2008-01-01

    In their role as caregivers supporting the children they teach, it is important for teachers to understand the grieving process and recognize symptoms of grief. The author explains Elisabeth Kubler-Ross's five stages of grief and offers 10 classroom strategies to help young children cope with their feelings.

  19. Child Development and Counseling.

    ERIC Educational Resources Information Center

    Elkind, David

    1980-01-01

    Outlines three constructs, the assumptive reality of childhood and the imaginary audience and personal fable of adolescence, which help explain normal and problem behavior. Counselors are asked to accept the young person's view of reality as valid and help him/her distinguish between personal and social reality. (Author)

  20. Infertility: A Crisis with No Resolution.

    ERIC Educational Resources Information Center

    Butler, Robert R.; Koraleski, Stephanie

    1990-01-01

    Discusses helpful ways for mental health counselors to work with infertile clients, explaining nature of infertility, psychological crisis it provokes, common reactions of infertile clients, and strategies to help clients cope. Discusses specific strategies for assessing clients' potential for suicide or self-destructive acts and improving their…

  1. The DYNAMO Simulation Language--An Alternate Approach to Computer Science Education.

    ERIC Educational Resources Information Center

    Bronson, Richard

    1986-01-01

    Suggests the use of computer simulation of continuous systems as a problem solving approach to computer languages. Outlines the procedures that the system dynamics approach employs in computer simulations. Explains the advantages of the special purpose language, DYNAMO. (ML)

  2. European temperature records of the past five centuries based on documentary information compared to climate simulations

    NASA Astrophysics Data System (ADS)

    Zorita, E.

    2009-09-01

    Two European temperature records for the past half-millennium, January-to-April air temperature for Stockholm (Sweden) and seasonal temperature for a Central European region, both derived from the analysis of documentary sources combined with long instrumental records, are compared with the output of forced (solar, volcanic, greenhouse gases) climate simulations with the model ECHO-G. The analysis is complemented with the long (early)-instrumental record of Central England Temperature (CET). Both approaches to study past climates (simulations and reconstructions) are burdened with uncertainties. The main objective of this comparative analysis is to identify robust features and weaknesses that may help to improve models and reconstruction methods. The results indicate a general agreement between simulations and the reconstructed Stockholm and CET records regarding the long-term temperature trend over the recent centuries, suggesting a reasonable choice of the amplitude of the solar forcing in the simulations and sensitivity of the model to the external forcing. However, the Stockholm reconstruction and the CET record also show a long and clear multi-decadal warm episode peaking around 1730, which is absent in the simulations. The uncertainties associated with the reconstruction method or with the simulated internal climate variability cannot easily explain this difference. Regarding the interannual variability, the Stockholm series displays in some periods higher amplitudes than the simulations but these differences are within the statistical uncertainty and further decrease if output from a regional model driven by the global model is used. The long-term trends in the simulations and reconstructions of the Central European temperature agree less well. The reconstructed temperature displays, for all seasons, a smaller difference between the present climate and past centuries than the simulations. Possible reasons for these differences may be related to a limitation of the traditional technique for converting documentary evidence to temperature values to capture long-term climate changes, because the documents often reflect temperatures relative to the contemporary authors' own perception of what constituted 'normal' conditions. By contrast, the simulated and reconstructed inter-annual variability is in rather good agreement.

  3. Rapid Dye Regeneration Mechanism of Dye-Sensitized Solar Cells.

    PubMed

    Jeon, Jiwon; Park, Young Choon; Han, Sang Soo; Goddard, William A; Lee, Yoon Sup; Kim, Hyungjun

    2014-12-18

    During the light-harvesting process of dye-sensitized solar cells (DSSCs), the hole localized on the dye after the charge separation yields an oxidized dye, D(+). The fast regeneration of D(+) using the redox pair (typically the I(-)/I3(-) couple) is critical for the efficient DSSCs. However, the kinetic processes of dye regeneration remain uncertain, still promoting vigorous debates. Here, we use molecular dynamics simulations to determine that the inner-sphere electron-transfer pathway provides a rapid dye regeneration route of ∼4 ps, where penetration of I(-) next to D(+) enables an immediate electron transfer, forming a kinetic barrier. This explains the recently reported ultrafast dye regeneration rate of a few picoseconds determined experimentally. We expect that our MD based comprehensive understanding of the dye regeneration mechanism will provide a helpful guideline in designing TiO2-dye-electrolyte interfacial systems for better performing DSSCs.

  4. e(sup +/-) Pair Loading and the Origin of the Upstream Magnetic Field in GRB Shocks

    NASA Technical Reports Server (NTRS)

    Ramirez-Ruiz, Enrico; Nishikawa, Ken-Ichi; Hededal, Christian B.

    2006-01-01

    We investigate here the effects of plasma instabilities driven by rapid e(sup +/-) pair cascades, which arise in the environment of GRB sources as a result of back-scattering of a seed fraction of their original spectrum. The injection of e(sup +/-) pairs induces strong streaming motions in the ambient medium. One therefore expects the pair-enriched medium ahead of the forward shock to be strongly sheared on length scales comparable to the radiation front thickness. Using three-dimensional particle-in-cell simulations, we show that plasma instabilities driven by these streaming e(sup +/-) pairs are responsible for the excitation of near-equipartition, turbulent magnetic fields. Our results reveal the importance of the electromagnetic filamentation instability in ensuring an effective coupling between e(sup +/-) pairs and ions, and may help explain the origin of large upstream fields in GRB shocks.

  5. e+/- Pair Loading and the Origin of the Upstream Field in GRB Shocks

    NASA Technical Reports Server (NTRS)

    Ramirez-Ruiz, Enrico; Nishikawa, Ken-Ichi; Hededal, Christian B.

    2006-01-01

    We investigate here the effects of plasma instabilities driven by rapid e(sup plus or minus) pair cascades, which arise in the environment of GRB sources as a result of back-scattering of a seed fraction of their original spectrum. The injection of e(sup plus or minus) pairs induces strong streaming motions in the ambient medium. One therefore expects the pair-enriched medium ahead of the forward shock to be strongly sheared on length scales comparable to the radiation front thickness. Using three-dimensional particle-in-cell simulations, we show that plasma instabilities driven by these streaming e(sup plus or minus) pairs are responsible for the excitation of near-equipartition, turbulent magnetic fields. Our results reveal the importance of the electromagnetic filamentation instability in ensuring an effective coupling between e(sup plus or minus) pairs and ions, and may help explain the origin of large upstream fields in GRB shocks.

  6. Application of MODFLOW for oil reservoir simulation during the Deepwater Horizon Crisis

    USGS Publications Warehouse

    Hsieh, Paul A.

    2011-01-01

    When the Macondo well was shut in on July 15, 2010, the shut-in pressure recovered to a level that indicated the possibility of oil leakage out of the well casing into the surrounding formation. Such a leak could initiate a hydraulic fracture that might eventually breach the seafloor, resulting in renewed and uncontrolled oil flow into the Gulf of Mexico. To help evaluate whether or not to reopen the well, a MODFLOW model was constructed within 24 h after shut in to analyze the shut-in pressure. The model showed that the shut-in pressure can be explained by a reasonable scenario in which the well did not leak after shut in. The rapid response provided a scientific analysis for the decision to keep the well shut, thus ending the oil spill resulting from the Deepwater Horizon blow out.

  7. Experimental study and modeling of atomic-scale friction in zigzag and armchair lattice orientations of MoS2.

    PubMed

    Li, Meng; Shi, Jialin; Liu, Lianqing; Yu, Peng; Xi, Ning; Wang, Yuechao

    2016-01-01

    Physical properties of two-dimensional materials, such as graphene, black phosphorus, molybdenum disulfide (MoS 2 ) and tungsten disulfide, exhibit significant dependence on their lattice orientations, especially for zigzag and armchair lattice orientations. Understanding of the atomic probe motion on surfaces with different orientations helps in the study of anisotropic materials. Unfortunately, there is no comprehensive model that can describe the probe motion mechanism. In this paper, we report a tribological study of MoS 2 in zigzag and armchair orientations. We observed a characteristic power spectrum and friction force values. To explain our results, we developed a modified, two-dimensional, stick-slip Tomlinson model that allows simulation of the probe motion on MoS 2 surfaces by combining the motion in the Mo layer and S layer. Our model fits well with the experimental data and provides a theoretical basis for tribological studies of two-dimensional materials.

  8. The Mediated MIMIC Model for Understanding the Underlying Mechanism of DIF.

    PubMed

    Cheng, Ying; Shao, Can; Lathrop, Quinn N

    2016-02-01

    Due to its flexibility, the multiple-indicator, multiple-causes (MIMIC) model has become an increasingly popular method for the detection of differential item functioning (DIF). In this article, we propose the mediated MIMIC model method to uncover the underlying mechanism of DIF. This method extends the usual MIMIC model by including one variable or multiple variables that may completely or partially mediate the DIF effect. If complete mediation effect is found, the DIF effect is fully accounted for. Through our simulation study, we find that the mediated MIMIC model is very successful in detecting the mediation effect that completely or partially accounts for DIF, while keeping the Type I error rate well controlled for both balanced and unbalanced sample sizes between focal and reference groups. Because it is successful in detecting such mediation effects, the mediated MIMIC model may help explain DIF and give guidance in the revision of a DIF item.

  9. The Mediated MIMIC Model for Understanding the Underlying Mechanism of DIF

    PubMed Central

    Cheng, Ying; Shao, Can; Lathrop, Quinn N.

    2015-01-01

    Due to its flexibility, the multiple-indicator, multiple-causes (MIMIC) model has become an increasingly popular method for the detection of differential item functioning (DIF). In this article, we propose the mediated MIMIC model method to uncover the underlying mechanism of DIF. This method extends the usual MIMIC model by including one variable or multiple variables that may completely or partially mediate the DIF effect. If complete mediation effect is found, the DIF effect is fully accounted for. Through our simulation study, we find that the mediated MIMIC model is very successful in detecting the mediation effect that completely or partially accounts for DIF, while keeping the Type I error rate well controlled for both balanced and unbalanced sample sizes between focal and reference groups. Because it is successful in detecting such mediation effects, the mediated MIMIC model may help explain DIF and give guidance in the revision of a DIF item.

  10. [Modeling in value-based medicine].

    PubMed

    Neubauer, A S; Hirneiss, C; Kampik, A

    2010-03-01

    Modeling plays an important role in value-based medicine (VBM). It allows decision support by predicting potential clinical and economic consequences, frequently combining different sources of evidence. Based on relevant publications and examples focusing on ophthalmology the key economic modeling methods are explained and definitions are given. The most frequently applied model types are decision trees, Markov models, and discrete event simulation (DES) models. Model validation includes besides verifying internal validity comparison with other models (external validity) and ideally validation of its predictive properties. The existing uncertainty with any modeling should be clearly stated. This is true for economic modeling in VBM as well as when using disease risk models to support clinical decisions. In economic modeling uni- and multivariate sensitivity analyses are usually applied; the key concepts here are tornado plots and cost-effectiveness acceptability curves. Given the existing uncertainty, modeling helps to make better informed decisions than without this additional information.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Porter, Edward K.; Cornish, Neil J.

    Massive black hole binaries are key targets for the space based gravitational wave Laser Interferometer Space Antenna (LISA). Several studies have investigated how LISA observations could be used to constrain the parameters of these systems. Until recently, most of these studies have ignored the higher harmonic corrections to the waveforms. Here we analyze the effects of the higher harmonics in more detail by performing extensive Monte Carlo simulations. We pay particular attention to how the higher harmonics impact parameter correlations, and show that the additional harmonics help mitigate the impact of having two laser links fail, by allowing for anmore » instantaneous measurement of the gravitational wave polarization with a single interferometer channel. By looking at parameter correlations we are able to explain why certain mass ratios provide dramatic improvements in certain parameter estimations, and illustrate how the improved polarization measurement improves the prospects for single interferometer operation.« less

  12. Analysis of Surface and Bulk Behavior in Ni-Pd Alloys

    NASA Technical Reports Server (NTRS)

    Bozzolo, Guillermo; Noebe, Rondald D.

    2003-01-01

    The most salient features of the surface structure and bulk behavior of Ni-Pd alloys have been studied using the BFS method for alloys. Large-scale atomistic simulations were performed to investigate surface segregation profiles as a function of temperature, crystal face, and composition. Pd enrichment of the first layer was observed in (111) and (100) surfaces, and enrichment of the top two layers occurred for (110) surfaces. In all cases, the segregation profile shows alternate planes enriched and depleted in Pd. In addition, the phase structure of bulk Ni-Pd alloys as a function of temperature and composition was studied. A weak ordering tendency was observed at low temperatures, which helps explain the compositional oscillations in the segregation profiles. Finally, based on atom-by-atom static energy calculations, a comprehensive explanation for the observed surface and bulk features will be presented in terms of competing chemical and strain energy effects.

  13. How Should Resident Physicians Respond to Patients' Discomfort and Students' Moral Distress When Learning Procedures in Academic Medical Settings?

    PubMed

    Miller, Bonnie M

    2017-06-01

    In this scenario, a medical student, Lauren, experiences moral distress because she feels that learning to perform a procedure on a patient who requested not to be used for "practice" puts her own interests above the patient's. Lauren might also worry that the resident physician is misrepresenting her abilities. The resident physician could help alleviate Lauren's distress and align her interests with the patient's by more clearly explaining the training situation to the patient and seeking the patient's approval. Lauren might also manage the situation by assuring the patient of the resident's supervisory role. This article argues that trainees should have the opportunities to practice procedures and difficult conversations in simulated settings and that institutions should support a culture of "speaking up" to ensure patients' and learners' safety. © 2017 American Medical Association. All Rights Reserved.

  14. Free energy landscape and localization of nanoparticles at block copolymer model defects.

    PubMed

    Kim, Yongjoo; Chen, Hsieh; Alexander-Katz, Alfredo

    2014-05-14

    Nanoparticle localization in block copolymer model defects is studied using self-consistent field theory simulations. In particular we study the nanoparticle free energy landscape for three different model defects: X, T, Y shape defects. Our results indicate that nanoparticles can be strongly bound to certain locations in these defects. The symmetry of the defects affects in a non-trivial fashion the "stiffness of the trap", with the X shape defect displaying the deepest energy well. The T and Y defects exhibit orientations along which the potential energy well is rather shallow. Furthermore, we find that the free energy well is tunable by the size of the nanoparticles. Our results help to explain recent experimental observations in block copolymer templated assembly of nanoparticles. Furthermore, they may open new avenues to assemble arbitrary heterogeneous patterns with precise nanoparticle positions by carefully controlling the morphology of a block copolymer system by using directed self-assembly techniques.

  15. Modelling a hydropower plant with reservoir with the micropower optimisation model (HOMER)

    NASA Astrophysics Data System (ADS)

    Canales, Fausto A.; Beluco, Alexandre; Mendes, Carlos André B.

    2017-08-01

    Hydropower with water accumulation is an interesting option to consider in hybrid systems, because it helps dealing with the intermittence characteristics of renewable energy resources. The software HOMER (version Legacy) is extensively used in research works related to these systems, but it does not include a specific option for modelling hydro with reservoir. This paper describes a method for modelling a hydropower plant with reservoir with HOMER by adapting an existing procedure used for modelling pumped storage. An example with two scenarios in southern Brazil is presented for illustrating and validating the method explained in this paper. The results validate the method by showing a direct correspondence between an equivalent battery and the reservoir. The refill of the reservoir, its power output as a function of the flow rate and installed hydropower capacity are effectively simulated, indicating an adequate representation of a hydropower plant with reservoir is possible with HOMER.

  16. The evolution of social learning mechanisms and cultural phenomena in group foragers.

    PubMed

    van der Post, Daniel J; Franz, Mathias; Laland, Kevin N

    2017-02-10

    Advanced cognitive abilities are widely thought to underpin cultural traditions and cumulative cultural change. In contrast, recent simulation models have found that basic social influences on learning suffice to support both cultural phenomena. In the present study we test the predictions of these models in the context of skill learning, in a model with stochastic demographics, variable group sizes, and evolved parameter values, exploring the cultural ramifications of three different social learning mechanisms. Our results show that that simple forms of social learning such as local enhancement, can generate traditional differences in the context of skill learning. In contrast, we find cumulative cultural change is supported by observational learning, but not local or stimulus enhancement, which supports the idea that advanced cognitive abilities are important for generating this cultural phenomenon in the context of skill learning. Our results help to explain the observation that animal cultures are widespread, but cumulative cultural change might be rare.

  17. Modeling fast and slow earthquakes at various scales

    PubMed Central

    IDE, Satoshi

    2014-01-01

    Earthquake sources represent dynamic rupture within rocky materials at depth and often can be modeled as propagating shear slip controlled by friction laws. These laws provide boundary conditions on fault planes embedded in elastic media. Recent developments in observation networks, laboratory experiments, and methods of data analysis have expanded our knowledge of the physics of earthquakes. Newly discovered slow earthquakes are qualitatively different phenomena from ordinary fast earthquakes and provide independent information on slow deformation at depth. Many numerical simulations have been carried out to model both fast and slow earthquakes, but problems remain, especially with scaling laws. Some mechanisms are required to explain the power-law nature of earthquake rupture and the lack of characteristic length. Conceptual models that include a hierarchical structure over a wide range of scales would be helpful for characterizing diverse behavior in different seismic regions and for improving probabilistic forecasts of earthquakes. PMID:25311138

  18. Modeling fast and slow earthquakes at various scales.

    PubMed

    Ide, Satoshi

    2014-01-01

    Earthquake sources represent dynamic rupture within rocky materials at depth and often can be modeled as propagating shear slip controlled by friction laws. These laws provide boundary conditions on fault planes embedded in elastic media. Recent developments in observation networks, laboratory experiments, and methods of data analysis have expanded our knowledge of the physics of earthquakes. Newly discovered slow earthquakes are qualitatively different phenomena from ordinary fast earthquakes and provide independent information on slow deformation at depth. Many numerical simulations have been carried out to model both fast and slow earthquakes, but problems remain, especially with scaling laws. Some mechanisms are required to explain the power-law nature of earthquake rupture and the lack of characteristic length. Conceptual models that include a hierarchical structure over a wide range of scales would be helpful for characterizing diverse behavior in different seismic regions and for improving probabilistic forecasts of earthquakes.

  19. Numerical simulation of microstructural damage and tensile strength of snow

    NASA Astrophysics Data System (ADS)

    Hagenmuller, Pascal; Theile, Thiemo C.; Schneebeli, Martin

    2014-01-01

    This contribution uses finite-element analysis to simulate microstructural failure processes and the tensile strength of snow. The 3-D structure of snow was imaged by microtomography. Modeling procedures used the elastic properties of ice with bond fracture assumptions as inputs. The microstructure experiences combined tensile and compressive stresses in response to macroscopic tensile stress. The simulated nonlocalized failure of ice lattice bonds before or after reaching peak stress creates a pseudo-plastic yield curve. This explains the occurrence of acoustic events observed in advance of global failure. The measured and simulated average tensile strengths differed by 35%, a typical range for strength measurements in snow given its low Weibull modulus. The simulation successfully explains damage, fracture nucleation, and strength according to the geometry of the microstructure of snow and the mechanical properties of ice. This novel method can be applied to more complex snow structures including the weak layers that cause avalanches.

  20. How Psychological Resources Mediate and Perceived Social Support Moderates the Relationship between Depressive Symptoms and Help-Seeking Intentions in College Students

    ERIC Educational Resources Information Center

    Kenny, Rachel; Dooley, Barbara; Fitzgerald, Amanda

    2016-01-01

    There is a high prevalence of depression among college students, which is linked to lower levels of help-seeking intentions. However, there has been a lack of research examining variables that may help explain this relationship. The present study aimed to address this gap by examining whether psychological resources (optimism and self-esteem)…

  1. ACARA user's manual

    NASA Technical Reports Server (NTRS)

    Stalnaker, Dale K.

    1993-01-01

    ACARA (Availability, Cost, and Resource Allocation) is a computer program which analyzes system availability, lifecycle cost (LCC), and resupply scheduling using Monte Carlo analysis to simulate component failure and replacement. This manual was written to: (1) explain how to prepare and enter input data for use in ACARA; (2) explain the user interface, menus, input screens, and input tables; (3) explain the algorithms used in the program; and (4) explain each table and chart in the output.

  2. Navigating Tensions Between Conceptual and Metaconceptual Goals in the Use of Models

    NASA Astrophysics Data System (ADS)

    Delgado, Cesar

    2015-04-01

    Science education involves learning about phenomena at three levels: concrete (facts and generalizations), conceptual (concepts and theories), and metaconceptual (epistemology) (Snir et al. in J Sci Educ Technol 2(2):373-388, 1993). Models are key components in science, can help build conceptual understanding, and may also build metaconceptual understanding. Technology can transform teaching and learning by turning models into interactive simulations that learners can investigate. This paper identifies four characteristics of models and simulations that support conceptual learning but misconstrue models and science at a metaconceptual level. Ahistorical models combine the characteristics of several historical models; they conveniently compile ideas but misrepresent the history of science (Gilbert in Int J Sci Math Educ 2(2):115-130, 2004). Teleological models explain behavior in terms of a final cause; they can lead to useful heuristics but imply purpose in processes driven by chance and probability (Talanquer in Int J Sci Educ 29(7):853-870, 2007). Epistemological overreach occurs when models or simulations imply greater certainty and knowledge about phenomena than warranted; conceptualizing nature as being well known (e.g., having a mathematical structure) poses the danger of conflating model and reality or data and theory. Finally, models are inevitably ontologically impoverished. Real-world deviations and many variables are left out of models, as models' role is to simplify. Models and simulations also lose much of the sensory data present in phenomena. Teachers, designers, and professional development designers and facilitators must thus navigate the tension between conceptual and metaconceptual learning when using models and simulations. For each characteristic, examples are provided, along with recommendations for instruction and design. Prompts for explicit reflective activities around models are provided for each characteristic

  3. Molecular dynamics simulations of the auxin-binding protein 1 in complex with indole-3-acetic acid and naphthalen-1-acetic acid.

    PubMed

    Grandits, Melanie; Oostenbrink, Chris

    2014-10-01

    Auxin-binding protein 1 (ABP1) is suggested to be an auxin receptor which plays an important role in several processes in green plants. Maize ABP1 was simulated with the natural auxin indole-3-acetic acid (IAA) and the synthetic analog naphthalen-1-acetic acid (NAA), to elucidate the role of the KDEL sequence and the helix at the C-terminus. The KDEL sequence weakens the intermolecular interactions between the monomers but stabilizes the C-terminal helix. Conformational changes at the C-terminus occur within the KDEL sequence and are influenced by the binding of the simulated ligands. This observation helps to explain experimental findings on ABP1 interactions with antibodies that are modulated by the presence of auxin, and supports the hypothesis that ABP1 acts as an auxin receptor. Stable hydrogen bonds between the monomers are formed between Glu40 and Glu62, Arg10 and Thr97, Lys39, and Glu62 in all simulations. The amino acids Ile22, Leu25, Trp44, Pro55, Ile130, and Phe149 are located in the binding pocket and are involved in hydrophobic interactions with the ring system of the ligand. Trp151 is stably involved in a face to end interaction with the ligand. The calculated free energy of binding using the linear interaction energy approach showed a higher binding affinity for NAA as compared to IAA. Our simulations confirm the asymmetric behavior of the two monomers, the stronger interaction of NAA than IAA and offers insight into the possible mechanism of ABP1 as an auxin receptor. © 2014 Wiley Periodicals, Inc.

  4. Analyzing Strategic Business Rules through Simulation Modeling

    NASA Astrophysics Data System (ADS)

    Orta, Elena; Ruiz, Mercedes; Toro, Miguel

    Service Oriented Architecture (SOA) holds promise for business agility since it allows business process to change to meet new customer demands or market needs without causing a cascade effect of changes in the underlying IT systems. Business rules are the instrument chosen to help business and IT to collaborate. In this paper, we propose the utilization of simulation models to model and simulate strategic business rules that are then disaggregated at different levels of an SOA architecture. Our proposal is aimed to help find a good configuration for strategic business objectives and IT parameters. The paper includes a case study where a simulation model is built to help business decision-making in a context where finding a good configuration for different business parameters and performance is too complex to analyze by trial and error.

  5. Dune formation on the Cooper Creek floodplain, Strzelecki Desert, Australia - first results of morphodynamic simulations

    NASA Astrophysics Data System (ADS)

    Kryger, Mateusz; Bubenzer, Olaf; Parteli, Eric

    2017-04-01

    Linear Dunes, which align longitudinally to the resultant wind vector, are the prevailing type of the south-north trending and partially vegetated dunes in the Strzelecki Desert, Australia. However, particularly on the Cooper Creek floodplain near Innamincka, striking complex dune features consisting of transversely oriented east-west trending dunes occur. These transverse dunes extend over several kilometers and are superimposed by linear dunes that elongate northwards and are separated by sandy swales. The aeolian features in the Strzelecki Desert are the result of interrelated late quaternary aeolian and fluvial activity and serve, thus, as archives providing information about variations in palaeoclimate and potential changes in fluvial sediment supply and wind strength and directionality. However, since the dunes are currently mostly stabilized by vegetation, it is uncertain whether their formation can be explained by the contemporary wind systems. To understand the dynamic processes underlying the genesis of the dune field in the Strzelecki Desert, the role of vegetation and the wind regimes leading to the observed dune patterns must be elucidated. Here we investigate the formative processes of the dune features occurring on the Cooper Creek floodplain by means of morphodynamic modeling of aeolian sand transport and dune formation in presence of vegetation growth. Our simulations show that a source-bordering dune can be formed out of the sediments of seasonally exposed sandbars of the palaeo-Cooper system by a unidirectional wind, which explains the emergence of the transverse dunes in the field. Moreover, a shift in the wind regime to obtuse bidirectional wind flows combined with a rapid decrease in the vegetation cover leads to the formation of linear dunes on the surface and in the lee of the transverse dunes. These linear dunes elongate over several kilometers downwind as a result of the seasonal wind changes. The dune shapes obtained in our simulations agree well with the real dune morphologies when a low vegetation growth rate is applied in the model. Although geochronological investigations, reported in the literature, on the Cooper Creek floodplain did not show the linear dunes declining in age downwind (which suggests the adjacent swales or the transverse dune to be the sediment source), our simulations show that strikingly similar linear dune morphologies can be obtained by sediment influx due to saltation alone. In this case, the bars of the palaeo-Cooper system might as well have served as the sediment source for the formation of the linear dunes. Therefore, our results suggest that a long-distance transport extension model could also explain the linear dune formation, while previous geochronological investigations supported the wind-rift vertical extension and wind-rift vertical accretion models. The morphodynamic simulations may thus not only help to reconstruct the palaeoenvironment of the northern Strzelecki Desert, but also provide insights for the interpretation of the sediment archives located on the Cooper Creek alluvial fan.

  6. Hydraulic continuity and biological effects of low strength very low frequency electromagnetic waves: Case of microbial biofilm growth in water treatment.

    PubMed

    Gérard, Merlin; Noamen, Omri; Evelyne, Gonze; Eric, Valette; Gilles, Cauffet; Marc, Henry

    2015-10-15

    This study aims to elucidate the interactions between water, subjected to electromagnetic waves of very low frequency (VLF) (kHz) with low strength electromagnetic fields (3.5 mT inside the coils), and the development of microbial biofilms in this exposed water. Experimental results demonstrate that in water exposed to VLF electromagnetic waves, the biomass of biofilm is limited if hydraulic continuity is achieved between the electromagnetic generator and the biofilm media. The measured amount of the biofilm's biomass is approximately a factor two lower for exposed biofilm than the non-exposed biofilm. Measurements of electromagnetic fields in the air and simulations exhibit very low intensities of fields (<10 nT and 2 V/m) in the biofilm-exposed region at a distance of 1 m from the electromagnetic generator. Exposure to electric and magnetic fields of the quoted intensities cannot explain thermal and ionizing effects on the biofilm. A variable electrical potential with a magnitude close to 20 mV was detected in the tank in hydraulic continuity with the electromagnetic generator. The application of quantum field theory may help to explain the observed effects in this case. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Simulation-Based Mission Rehearsal as a Human Activity System.

    DTIC Science & Technology

    1996-09-01

    explain this demonstrated importance of the people involved in MR, a human activity system model of simulation-based rehearsal was developed. It provides...Implications of this human activity system view are discussed, including: places in the mission preparation process where simulation can benefit operations

  8. For Parents: An Introduction to Kindergarten.

    ERIC Educational Resources Information Center

    New Brunswick Dept. of Education, Fredericton. Student Services Branch.

    This booklet for parents explains the activities that take place in kindergarten and the characteristics of kindergarten staff. Also discussed is the manner in which the activities and staff help children develop. Activities considered center around dramatic play; children helping themselves and others; pets; cooking; snacks; exercise; reading and…

  9. Images of Atoms.

    ERIC Educational Resources Information Center

    Wright, Tony

    2003-01-01

    Recommends using a simple image, such as the fuzzy atom ball to help students develop a useful understanding of the molecular world. Explains that the image helps students easily grasp ideas about atoms and molecules and leads naturally to more advanced ideas of atomic structure, chemical bonding, and quantum physics. (Author/NB)

  10. The Joy of Moving, Singing, and Being Silly.

    ERIC Educational Resources Information Center

    Liebler, Scott

    1997-01-01

    Explains how moving, singing, and having fun build character, confidence, and coordination while helping children grow up feeling good about themselves. These activities provide an integrated, multisensory approach to learning. Employing a variety of fun and effective activities also helps children release stress and tension. (TJQ)

  11. Issues and Strategies Involved in Helping Homeless Parents of Young Children Strengthen Their Self-Esteem

    ERIC Educational Resources Information Center

    Swick, Kevin J.

    2009-01-01

    Homeless parents of young children face many stressors that erode their self-esteem. This article articulates these stressors and how they negatively impact homeless parents and their children. Strategies for helping parents empower themselves and their children are explained.

  12. Reaching Resistant Youth through Writing.

    ERIC Educational Resources Information Center

    Skramstad, Teresa

    1998-01-01

    A teacher recounts her experiences with students who were successful telling their stories through writing and using their writing as a vehicle for expressing their emotions. Explains how helping students "find their voices" through writing can crack tough exteriors and help youth reconnect to school and themselves. (Author/MKA)

  13. Perceived justice and popular support for public health laws: a case study around comprehensive smoke-free legislation in Mexico City.

    PubMed

    Thrasher, James F; Besley, John C; González, Wendy

    2010-03-01

    The World Health Organization's Framework Convention on Tobacco Control promotes comprehensive smoke-free laws. The effective implementation of these laws requires citizen participation and support. Risk communication research suggests that citizens' perceptions of the fairness of smoke-free laws would help explain their support for the law. This study aimed to assess the factors that correlate with citizens' perceptions of the distributive, procedural and interpersonal justice of smoke-free laws, as well as how these perceptions are related to support for and intention to help enforce these laws. Study data came from a cross-sectional, population-based survey of 800 Mexico City inhabitants before a comprehensive smoke-free policy was implemented there in 2008. Structural equation modeling was used to estimate the bivariate and multivariate adjusted paths relating study variables. In the final multivariate model, the three justice concepts mediated the influence of smoking status, perceived dangers of secondhand smoke exposure, strength of home smoking ban, and perceived rights of smokers on the two distal constructs of support for smoke-free policy and intention to help enforce it. Statistically significant paths were estimated from distributive and procedural justice to support for the law and intention help enforce it. The path from interpersonal justice to support for the law was not significant, but the path to intention to help enforce the law was. Finally, the path from support for the law to the intention to enforce it was statistically significant. These results suggest that three distinct dimensions of perceived justice help explain citizen support for smoke-free policies. These dimensions of perceived justice may explain the conditions under which smoke-free policies are effectively implemented and could help shape the focus for communication strategies that aim to ensure effective implementation of this and other public health policies. 2009 Elsevier Ltd. All rights reserved.

  14. 3D simulation for solitons used in optical fibers

    NASA Astrophysics Data System (ADS)

    Vasile, F.; Tebeica, C. M.; Schiopu, P.; Vladescu, M.

    2016-12-01

    In this paper is described 3D simulation for solitions used in optical fibers. In the scientific works is started from nonlinear propagation equation and the solitons represents its solutions. This paper presents the simulation of the fundamental soliton in 3D together with simulation of the second order soliton in 3D. These simulations help in the study of the optical fibers for long distances and in the interactions between the solitons. This study helps the understanding of the nonlinear propagation equation and for nonlinear waves. These 3D simulations are obtained using MATLAB programming language, and we can observe fundamental difference between the soliton and the second order/higher order soliton and in their evolution.

  15. A Simulation of Coevolution Using Playing Cards

    ERIC Educational Resources Information Center

    Tatina, Robert

    2007-01-01

    In this article, the author describes a simulation of a coevolutionary "arms race" and introduce a way of teaching it that lets students use the theory of natural selection to explain the outcomes of the simulation. The simulation uses the numerical cards from an UNO[R] playing card deck to represent the speeds of individuals in populations of…

  16. Simulation Using Novel Equipment Designed to Explain Spirometric Abnormalities in Respiratory Disease Enhances Learning in Higher Cognitive Domains

    ERIC Educational Resources Information Center

    Jamison, J. P.; Stewart, M. T.

    2015-01-01

    Simulation of disorders of respiratory mechanics shown by spirometry provides insight into the pathophysiology of disease but some clinically important disorders have not been simulated and none have been formally evaluated for education. We have designed simple mechanical devices which, along with existing simulators, enable all the main…

  17. Defining Environmental Education. Workshop Resource Manual.

    ERIC Educational Resources Information Center

    Disinger, John F.; Monroe, Martha C.

    This booklet is one in a series of resource manuals to help teacher educators conduct environmental education (EE) teacher workshops or promote EE programs. This unit is an orientation to the field of EE. It offers a definition of EE and some ways to explain its value to educators and environmental managers. The unit explains current and…

  18. Using Teacher-Developed Corpora in the CBI Classroom

    ERIC Educational Resources Information Center

    Salsbury, Tom; Crummer, Crista

    2008-01-01

    This article argues for the use of teacher-generated corpora in content-based courses. Using a content course for engineering and architecture students as an example, the article explains how a corpus consisting of texts from textbooks and journal articles helped students learn grammar, vocabulary, and writing. The article explains how the corpus…

  19. "Shalom Achshav"--The Rituals of the Israeli Peace Movement.

    ERIC Educational Resources Information Center

    Frank, David A.

    Noting that rhetorical critics have ignored the study of nonwestern movements and have failed to construct theories that help to explain and interpret the rhetorical form of such movements, this paper synthesizes concepts from rhetorical theory and anthropology to explain the linguistic process that made up the 1978 Israeli peace movement. The…

  20. New From Online: Toying With Chemistry

    ERIC Educational Resources Information Center

    Harris, Julie; Kehoe, Steven

    2005-01-01

    Toys which can help to learn the basics and more in-depth chemistry concept are investigated and explained, which are also available online on the website. Some of the examples are simple LCD clock powered by citric acid of lemon, crystal radio made from simple household materials, firework, homemade snow globe, which explains the properties of…

  1. Organizing to Use Facebook Advertisements: A Planning Tool for Extension Professionals, Businesses, and Communities

    ERIC Educational Resources Information Center

    Barnes, James

    2016-01-01

    The purpose of this article is to explain how Extension professionals, businesses, and communities can use Facebook advertisements effectively. The article is a planning tool that introduces Facebook's Advertiser Help Center, explains some applicable key concepts, and suggests best practices to apply before launching a Facebook advertising…

  2. Contradictions between and within School and University Activity Systems Helping to Explain Students' Difficulty with Advanced Mathematics

    ERIC Educational Resources Information Center

    Jooganah, Kamila; Williams, Julian S.

    2016-01-01

    This article explores how contradictions, as framed by activity theory (Engeström, 1987), can explain first-year undergraduate students' experiences of learning advanced mathematics. Analysing qualitative interview and observational data of students and lecturers based in one university mathematics department, we argue that contradictions between…

  3. NASFAA's Cash for College.

    ERIC Educational Resources Information Center

    National Association of Student Financial Aid Administrators, Washington, DC.

    This guide advises students about college costs and how to pay them. The booklet explains financial aid and how it can help a student reach his or her educational goals. Merit-based and need-based aid programs are described, and the family's expected financial contribution is explained. The process of obtaining and completing the Free Application…

  4. Changing Our Minds: The Struggle To Generate a Humanistic Neuroscience Language through Metaphors from Quantum Physics.

    ERIC Educational Resources Information Center

    Liston, Delores D.

    While the physiological explanations from neuroscience help explain the mechanisms of learning, they fall short of explaining the sociocultural and phenomenological factors that determine a stressful versus a challenging interpretation of experience. For this reason, neuroscience seems less than useful to classroom teachers. A major obstacle in…

  5. Testing the Two-Layer Model for Correcting Near Cloud Reflectance Enhancement Using LES SHDOM Simulated Radiances

    NASA Technical Reports Server (NTRS)

    Wen, Guoyong; Marshak, Alexander; Varnai, Tamas; Levy, Robert

    2016-01-01

    A transition zone exists between cloudy skies and clear sky; such that, clouds scatter solar radiation into clear-sky regions. From a satellite perspective, it appears that clouds enhance the radiation nearby. We seek a simple method to estimate this enhancement, since it is so computationally expensive to account for all three-dimensional (3-D) scattering processes. In previous studies, we developed a simple two-layer model (2LM) that estimated the radiation scattered via cloud-molecular interactions. Here we have developed a new model to account for cloud-surface interaction (CSI). We test the models by comparing to calculations provided by full 3-D radiative transfer simulations of realistic cloud scenes. For these scenes, the Moderate Resolution Imaging Spectroradiometer (MODIS)-like radiance fields were computed from the Spherical Harmonic Discrete Ordinate Method (SHDOM), based on a large number of cumulus fields simulated by the University of California, Los Angeles (UCLA) large eddy simulation (LES) model. We find that the original 2LM model that estimates cloud-air molecule interactions accounts for 64 of the total reflectance enhancement and the new model (2LM+CSI) that also includes cloud-surface interactions accounts for nearly 80. We discuss the possibility of accounting for cloud-aerosol radiative interactions in 3-D cloud-induced reflectance enhancement, which may explain the remaining 20 of enhancements. Because these are simple models, these corrections can be applied to global satellite observations (e.g., MODIS) and help to reduce biases in aerosol and other clear-sky retrievals.

  6. CO-ORBITING PLANES OF SUB-HALOS ARE SIMILARLY UNLIKELY AROUND PAIRED AND ISOLATED HOSTS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pawlowski, Marcel S.; McGaugh, Stacy S., E-mail: marcel.pawlowski@case.edu

    2014-07-01

    Sub-halos in dark-matter-based cosmological simulations tend to be distributed approximately isotropically around their host. The existence of highly flattened, co-orbiting planes of satellite galaxies has therefore been identified as a possible problem for these cosmological models, but so far studies have not considered the hosts' environments. That satellite planes are now known around both major galaxies in the Local Group raises the question whether they are more likely to be found around paired hosts. In a first attempt to investigate this possibility, we focus on the flattening and orbital coherence of the 11 brightest satellite galaxies of the vast polarmore » structure (VPOS) around the Milky Way (MW). We search for VPOS analogs in the ''Exploring the Local Volume in Simulations'' suite of cosmological simulations, which consist of 24 paired and 24 isolated host halos. We do not find significant differences between the properties of sub-halo distributions around paired and isolated hosts. The observed flattening and the observed orbital alignment are each reproduced by only 0.2%-2% of paired and isolated systems incorporating the obscuration of satellites by randomly oriented galactic disks. Only 1 of all 4800 analyzed realizations (0.02%) reproduces both parameters simultaneously, but the average orbital pole of this sub-halo system does not align as well with the normal to the plane fit as observed. That the MW is part of a galaxy pair thus does not help to explain the existence of the VPOS if the satellite galaxies are identified with sub-halos found in dissipationless simulations.« less

  7. Linking long-term planetary N-body simulations with periodic orbits: application to white dwarf pollution

    NASA Astrophysics Data System (ADS)

    Antoniadou, Kyriaki I.; Veras, Dimitri

    2016-12-01

    Mounting discoveries of debris discs orbiting newly formed stars and white dwarfs (WDs) showcase the importance of modelling the long-term evolution of small bodies in exosystems. WD debris discs are, in particular, thought to form from very long-term (0.1-5.0 Gyr) instability between planets and asteroids. However, the time-consuming nature of N-body integrators which accurately simulate motion over Gyrs necessitates a judicious choice of initial conditions. The analytical tools known as periodic orbits can circumvent the guesswork. Here, we begin a comprehensive analysis directly linking periodic orbits with N-body integration outcomes with an extensive exploration of the planar circular restricted three-body problem (CRTBP) with an outer planet and inner asteroid near or inside of the 2:1 mean motion resonance. We run nearly 1000 focused simulations for the entire age of the Universe (14 Gyr) with initial conditions mapped to the phase space locations surrounding the unstable and stable periodic orbits for that commensurability. In none of our simulations did the planar CRTBP architecture yield a long-time-scale (≳0.25 per cent of the age of the Universe) asteroid-star collision. The pericentre distance of asteroids which survived beyond this time-scale (≈35 Myr) varied by at most about 60 per cent. These results help affirm that collisions occur too quickly to explain WD pollution in the planar CRTBP 2:1 regime, and highlight the need for further periodic orbit studies with the eccentric and inclined TBP architectures and other significant orbital period commensurabilities.

  8. A driving simulator study of driver performance on deceleration lanes.

    PubMed

    Calvi, A; Benedetto, A; De Blasiis, M R

    2012-03-01

    Deceleration lanes are important because they help drivers transition from high-speed lanes to low-speed ramps. Although they are designed to allow vehicles to depart the freeway safely and efficiently, many studies report high accident rates on exit ramps with the highest percentage of crashes taking place in deceleration lanes. This paper describes the results of a driving simulator study that focused on driving performance while approaching a divergence area and decelerating during the exiting maneuver. Three different traffic scenarios were simulated to analyze the influence of traffic volume on driving performance. Thirty drivers drove in the simulator in these scenarios while data on their lateral position, speed and deceleration were collected. Our results indicate there are considerable differences between the main assumptions of models generally used to design deceleration lanes and actual driving performance. In particular, diverging drivers begin to decelerate before arriving at the deceleration lane, causing interference with the main flow. Moreover, speeds recorded at the end of the deceleration lane exceed those for which the ramp's curves are designed; this creates risky driving conditions that could explain the high crash rates found in studies of exit ramps. Finally, statistical analyses demonstrate significant influences of traffic volume on some aspects of exiting drivers' performance: lower traffic volume results in elevated exiting speed and deceleration, and diverging drivers begin to decelerate earlier along the main lane when traffic volume is low. However, speeds at the end of the deceleration lane and the site of lane changing are not significantly influenced by traffic volume. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Using rainfall simulations to understand the relationship between precipitation, soil crust and infiltration in four agricultural soils

    NASA Astrophysics Data System (ADS)

    Angulo-Martinez, Marta; Alastrué, Juan; Moret-Fernández, David; Beguería, Santiago; López, Mariví; Navas, Ana

    2017-04-01

    Rainfall simulation experiments were carried out in order to study soil crust formation and its relation with soil infiltration parameters—sorptivity (S) and hydraulic conductivity (K)—on four common agricultural soils with contrasted properties; namely, Cambisol, Gypsisol, Solonchak, and Solonetz. Three different rainfall simulations, replicated three times each of them, were performed over the soils. Prior to rainfall simulations all soils were mechanically tilled with a rototiller to create similar soil surface conditions and homogeneous soils. Rainfall simulation parameters were monitored in real time by a Thies Laser Precipitation Monitor, allowing a complete characterization of simulated rainfall microphysics (drop size and velocity distributions) and integrated variables (accumulated rainfall, intensity and kinetic energy). Once soils dried after the simulations, soil penetration resistance was measured and soil hydraulic parameters, S and K, were estimated using the disc infiltrometry technique. There was little variation in rainfall parameters among simulations. Mean intensity and mean median diameter (D50) varied in simulations 1 ( 0.5 bar), 2 ( 0.8 bar) and 3 ( 1.2 bar) from 26.5 mm h-1 and 0.43 mm (s1) to 40.5 mm h-1 and 0.54 mm (s2) and 41.1 mm h-1 and 0.56 mm for (s3), respectively. Crust formation by soil was explained by D50 and subsequently by the total precipitation amount and the percentage of silt and clay in soil, being Cambisol and Gypsisol the soils that showed more increase in penetration resistance by simulation. All soils showed similar S values by simulations which were explained by rainfall intensity. Different patterns of K were shown by the four soils, which were explained by the combined effect of D50 and intensity, together with soil physico-chemical properties. This study highlights the importance of monitoring all precipitation parameters to determine their effect on different soil processes.

  10. Increased ventilation of Antarctic deep water during the warm mid-Pliocene.

    PubMed

    Zhang, Zhongshi; Nisancioglu, Kerim H; Ninnemann, Ulysses S

    2013-01-01

    The mid-Pliocene warm period is a recent warm geological period that shares similarities with predictions of future climate. It is generally held the mid-Pliocene Atlantic Meridional Overturning Circulation must have been stronger, to explain a weak Atlantic meridional δ(13)C gradient and large northern high-latitude warming. However, climate models do not simulate such stronger Atlantic Meridional Overturning Circulation, when forced with mid-Pliocene boundary conditions. Proxy reconstructions allow for an alternative scenario that the weak δ(13)C gradient can be explained by increased ventilation and reduced stratification in the Southern Ocean. Here this alternative scenario is supported by simulations with the Norwegian Earth System Model (NorESM-L), which simulate an intensified and slightly poleward shifted wind field off Antarctica, giving enhanced ventilation and reduced stratification in the Southern Ocean. Our findings challenge the prevailing theory and show how increased Southern Ocean ventilation can reconcile existing model-data discrepancies about Atlantic Meridional Overturning Circulation while explaining fundamental ocean features.

  11. Increased ventilation of Antarctic deep water during the warm mid-Pliocene

    PubMed Central

    Zhang, Zhongshi; Nisancioglu, Kerim H.; Ninnemann, Ulysses S.

    2013-01-01

    The mid-Pliocene warm period is a recent warm geological period that shares similarities with predictions of future climate. It is generally held the mid-Pliocene Atlantic Meridional Overturning Circulation must have been stronger, to explain a weak Atlantic meridional δ13C gradient and large northern high-latitude warming. However, climate models do not simulate such stronger Atlantic Meridional Overturning Circulation, when forced with mid-Pliocene boundary conditions. Proxy reconstructions allow for an alternative scenario that the weak δ13C gradient can be explained by increased ventilation and reduced stratification in the Southern Ocean. Here this alternative scenario is supported by simulations with the Norwegian Earth System Model (NorESM-L), which simulate an intensified and slightly poleward shifted wind field off Antarctica, giving enhanced ventilation and reduced stratification in the Southern Ocean. Our findings challenge the prevailing theory and show how increased Southern Ocean ventilation can reconcile existing model-data discrepancies about Atlantic Meridional Overturning Circulation while explaining fundamental ocean features. PMID:23422667

  12. Evaluating the Relationship between Simulation and Clinical Decision-Making in Physical Therapy Students

    ERIC Educational Resources Information Center

    Macauley, Kelly

    2017-01-01

    Physical therapy students are frequently ill-prepared to practice in the dynamic healthcare environment immediately after graduation. Implementing other teaching modalities may help to better prepare physical therapy graduates. Medical student and nursing education have effectively used simulation to help prepare students effectively for clinical…

  13. Conceptual Modeling Framework for E-Area PA HELP Infiltration Model Simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dyer, J. A.

    A conceptual modeling framework based on the proposed E-Area Low-Level Waste Facility (LLWF) closure cap design is presented for conducting Hydrologic Evaluation of Landfill Performance (HELP) model simulations of intact and subsided cap infiltration scenarios for the next E-Area Performance Assessment (PA).

  14. Application of molecular simulation to investigate chrome(III)-crosslinked collagen problems

    NASA Astrophysics Data System (ADS)

    Ding, Yun-Qiao; Chen, Cheng-Lung; Gu, Qi-Rui; Liao, Jun-Min; Chuang, Po-Hsiang

    2014-04-01

    Molecular dynamics simulation with a modified CHARMM (Chemistry at Harvard Macromolecular Mechanics) force field was carried out to investigate the properties of chrome-tanned collagen in comparison with chrome-free collagen under hydrated and dehydrated conditions. An attempt has been made to explain the microcosmic origins of the various properties of the chromium(III)-crosslinked collagen. The present simulation describes the clear crosslinking topology of polychromiums to peptide chains, identifies the linking site and the capacity of the linkage, explains why the efficiency is not 100% in a practical tanning process and provides a new viewpoint on the crosslinking of the polychromium with the side chains of the collagen.

  15. Ready, Willing, and Able

    ERIC Educational Resources Information Center

    Bouffard, Suzanne M.; Savitz-Romer, Mandy

    2012-01-01

    Where students are in their development shapes how they behave and whether they succeed. An awareness of how students develop identity and motivation can help educators guide students as they set goals for the future. Bouffard and Savitz-Romer share strategies for helping students see themselves as college graduates. They also explain how the…

  16. A Token Manual for Behavior Analysis Classrooms.

    ERIC Educational Resources Information Center

    Bushell, Don, Jr.

    This dual language manual, written in both Spanish and English, will help the teacher in a Behavior Analysis classroom utilize the Token System to motivate, reinforce, and foster independence in pupils' learning activities. The rationale and procedures for earning, giving, and exchanging tokens is clearly explained. The use of helpful accessories…

  17. Moving On: Young People and Substance Abuse

    ERIC Educational Resources Information Center

    Daley, Kathryn; Chamberlain, Chris

    2009-01-01

    To help explain why some young people move from recreational drug use to substance abuse, twelve in-depth interviews were conducted with young people who had experienced problematic substance use. The data were supplemented by statistical data on 111 young people. The researchers found a variety of "structural" factors that help explain…

  18. Library Dream Machines: Helping Students Master Super Online Catalogs.

    ERIC Educational Resources Information Center

    Webb, T. D.

    1992-01-01

    Describes how automation has transformed the library and how super-catalogs have affected the process of doing research. Explains how faculty and librarians can work together to help students to use the available databases effectively, by teaching them Boolean logic, standard record formats, filing rules, etc. (DMM)

  19. Talking about the Facts of Education Data with School Board Members

    ERIC Educational Resources Information Center

    Data Quality Campaign, 2014

    2014-01-01

    The Data Quality Campaign and the National School Boards Association's Center for Public Education prepared this document to help school board members respond to questions about education data, explain its importance to improving school and student performance, and understand how boards can help ensure student privacy.

  20. How Advertising History Helps Explain Current Practices.

    ERIC Educational Resources Information Center

    Lanfranco, Leonard W.

    Students majoring in advertising can benefit from a study of that field in its historical context because such study helps them to understand current practices and to foresee future developments. One model of teaching advertising history within a required course about advertising and society begins with some basic definitions of the advertising…

  1. Museum Theatre: Telling Stories through Objects.

    ERIC Educational Resources Information Center

    Schindel, Dorothy Napp

    2002-01-01

    Explains that Museum Theatre's goal is to teach through drama by using experiential interpretive strategies that bypass the lecture format. Outlines a production of Museum Theatre which helped a museum redefine itself. Concludes that Museum Theatre helps shift the focus of programming from simple object display to an emphasis on the human…

  2. The Benefits of Scientific Modeling

    ERIC Educational Resources Information Center

    Kenyon, Lisa; Schwarz, Christina; Hug, Barbara

    2008-01-01

    When students are engaged in scientific modeling, they are able to notice patterns and develop and revise representations that become useful models to predict and explain--making their own scientific knowledge stronger, helping them to think critically, and helping them know more about the nature of science. To illustrate, this article describes a…

  3. From Hospital to School: How a Transition Liaison Can Help.

    ERIC Educational Resources Information Center

    Stuart, Judy L.; Goodsitt, Jodi L.

    1996-01-01

    The role of the transition liaison professional, who is knowledgeable in medical terminology, hospital procedures, and educational/community services for helping children with chronic illnesses, is explained. Discussion covers effects of recent laws, the need for a formal discharge program and planning model, and the many functions of the…

  4. School of Law

    ERIC Educational Resources Information Center

    Olsen, Ken

    2005-01-01

    This article explains how Street Law helps teachers to defuse tensions between students and police through a combination of education, empathy, and expertise. Street Law was born at Georgetown in 1972. Every year, it sends two dozen law students like Courtney Donovan into Washington, D.C., high schools to help teach the year long course. Street…

  5. Multiphysics modeling of two-phase film boiling within porous corrosion deposits

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jin, Miaomiao, E-mail: mmjin@mit.edu; Short, Michael, E-mail: hereiam@mit.edu

    2016-07-01

    Porous corrosion deposits on nuclear fuel cladding, known as CRUD, can cause multiple operational problems in light water reactors (LWRs). CRUD can cause accelerated corrosion of the fuel cladding, increase radiation fields and hence greater exposure risk to plant workers once activated, and induce a downward axial power shift causing an imbalance in core power distribution. In order to facilitate a better understanding of CRUD's effects, such as localized high cladding surface temperatures related to accelerated corrosion rates, we describe an improved, fully-coupled, multiphysics model to simulate heat transfer, chemical reactions and transport, and two-phase fluid flow within these deposits.more » Our new model features a reformed assumption of 2D, two-phase film boiling within the CRUD, correcting earlier models' assumptions of single-phase coolant flow with wick boiling under high heat fluxes. This model helps to better explain observed experimental values of the effective CRUD thermal conductivity. Finally, we propose a more complete set of boiling regimes, or a more detailed mechanism, to explain recent CRUD deposition experiments by suggesting the new concept of double dryout specifically in thick porous media with boiling chimneys. - Highlights: • A two-phase model of CRUD's effects on fuel cladding is developed and improved. • This model eliminates the formerly erroneous assumption of wick boiling. • Higher fuel cladding temperatures are predicted when accounting for two-phase flow. • Double-peaks in thermal conductivity vs. heat flux in experiments are explained. • A “double dryout” mechanism in CRUD is proposed based on the model and experiments.« less

  6. Factors affecting nutrient trends in major rivers of the Chesapeake Bay Watershed

    USGS Publications Warehouse

    Sprague, Lori A.; Langland, M.J.; Yochum, S.E.; Edwards, R.E.; Blomquist, J.D.; Phillips, S.W.; Shenk, G.W.; Preston, S.D.

    2000-01-01

    Trends in nutrient loads and flow-adjusted concentrations in the major rivers entering Chesapeake Bay were computed on the basis of water-quality data collected between 1985 and 1998 at 29 monitoring stations in the Susquehanna, Potomac, James, Rappahannock, York, Patuxent, and Choptank River Basins. Two computer models?the Chesapeake Bay Watershed Model (WSM) and the U.S. Geological Survey?s 'Spatially Referenced Regressions on Watershed attributes' (SPARROW) Model?were used to help explain the major factors affecting the trends. Results from WSM simulations provided information on temporal changes in contributions from major nutrient sources, and results from SPARROW model simulations provided spatial detail on the distribution of nutrient yields in these basins. Additional data on nutrient sources, basin characteristics, implementation of management practices, and ground-water inputs to surface water were analyzed to help explain the trends. The major factors affecting the trends were changes in nutrient sources and natural variations in streamflow. The dominant source of nitrogen and phosphorus from 1985 to 1998 in six of the seven tributary basins to Chesapeake Bay was determined to be agriculture. Because of the predominance of agricultural inputs, changes in agricultural nutrient sources such as manure and fertilizer, combined with decreases in agricultural acreage and implementation of best management practices (BMPs), had the greatest impact on the trends in flow-adjusted nutrient concentrations. Urban acreage and population, however, were noted to be increasing throughout the Chesapeake Bay Watershed, and as a result, delivered loads of nutrients from urban areas increased during the study period. Overall, agricultural nutrient management, in combination with load decreases from point sources due to facility upgrades and the phosphate detergent ban, led to downward trends in flow-adjusted nutrient concentrations atmany of the monitoring stations in the watershed. The loads of nutrients, however, were not reduced significantly at most of the monitoring stations. This is due primarily to higher streamflow in the latter years of the monitoring period, which led to higher loading in those years.Results of this study indicate a need for more detailed information on BMP effectiveness under a full range of hydrologic conditions and in different areas of the watershed; an internally consistent fertilizer data set; greater consideration of the effects of watershed processes on nutrient transport; a refinement of current modeling efforts; and an expansion of the non-tidal monitoring network in the Chesapeake Bay Watershed.

  7. Effects of aging on the relation between episodic simulation and prosocial intentions.

    PubMed

    Gaesser, Brendan; Dodds, Haley; Schacter, Daniel L

    2017-10-01

    Imagining helping a person in need can facilitate prosocial intentions. Here we investigated how this effect can change with aging. We found that, similar to young adults, older adults were more willing to help a person in need when they imagined helping that person compared to a baseline condition that did not involve helping, but not compared to a conceptual helping control condition. Controlling for heightened emotional concern in older adults revealed an age-related difference in the effect of imagining on willingness to help. While we observed age-related condition effects, we also found that the subjective vividness of scene imagery predicted willingness to help for both age groups. Our findings provide insight into the relations among episodic simulation, healthy aging, emotion, and prosociality. Implications for effects of episodic memory and aging on social decision-making are discussed.

  8. A Study of the Pre-Licensure Nursing Students' Perception of the Simulation Learning Environment as Helpful in Achieving Clinical Competencies and Their Perception of the Impact of the Level of Fidelity

    ERIC Educational Resources Information Center

    Crary, Wendy M.

    2012-01-01

    The research question of this study was: to what degree do nursing students perceive using the High Fidelity Simulation (HFS) learning environment to be helpful in their ability to achieve clinical competency. The research sub-questions (7) explored the students' demographics as an influence on rating of reality and helpfulness and the…

  9. Bereaved adults' evaluations of grief management messages: effects of message person centeredness, recipient individual differences, and contextual factors.

    PubMed

    Rack, Jessica J; Burleson, Brant R; Bodie, Graham D; Holmstrom, Amanda J; Servaty-Seib, Heather

    2008-01-01

    This study identifies grief management strategies that bereaved adults evaluate as more and less helpful, assesses whether the person centeredness of these strategies explains their helpfulness, and determines whether strategy helpfulness varies as a function of demographic, personality, and situational factors. Participants (105 bereaved young adults) assessed the helpfulness of 16 grief management strategies; these strategies were coded for their degree of person centeredness. Strategy person centeredness was strongly correlated with helpfulness. Strategy helpfulness varied as a function of participant gender and the disruptiveness of the decedent's death, but not as a function of need for cognition or decedent closeness.

  10. Asymmetric Eyewall Vertical Motion in a High-Resolution Simulation of Hurricane Bonnie (1998)

    NASA Technical Reports Server (NTRS)

    Braun, Scott A.; Montgomery, Michael T.; Pu, Zhao-Xia

    2003-01-01

    This study examines a high-resolution simulation of Hurricane Bonnie. Results from the simulation will be compared to the conceptual model of Heymsfield et al. (2001) to determine the extent to which this conceptual model explains vertical motions and precipitation growth in the eyewall.

  11. Simulation/Gaming in the EAP Writing Class: Benefits and Drawbacks.

    ERIC Educational Resources Information Center

    Salies, Tania Gastao

    2002-01-01

    Describes an integrated use of simulation/gaming in an English for Academic Purposes (EAP) class, analyzes benefits and drawbacks, and suggest how the technique could apply to other specific contexts. Explains how international students ran a simulation on gun control; discusses the debriefing process; and considers motivation, metacognitive…

  12. Confronting Global Issues: A Multipurpose IR Simulation

    ERIC Educational Resources Information Center

    Shellman, Stephen M.; Turan, Kursad

    2006-01-01

    This article describes an international relations simulation that focuses on threats of transnational insurgent organizations, the future of the Iraqi regime, and the effect of globalization on foreign policies. It contains both the Simulation Director's Guide and the Participant's Guide. The guides explain the steps taken to run the simulation…

  13. Zero-gravity movement studies

    NASA Technical Reports Server (NTRS)

    Badler, N. I.; Fishwick, P.; Taft, N.; Agrawala, M.

    1985-01-01

    The use of computer graphics to simulate the movement of articulated animals and mechanisms has a number of uses ranging over many fields. Human motion simulation systems can be useful in education, medicine, anatomy, physiology, and dance. In biomechanics, computer displays help to understand and analyze performance. Simulations can be used to help understand the effect of external or internal forces. Similarly, zero-gravity simulation systems should provide a means of designing and exploring the capabilities of hypothetical zero-gravity situations before actually carrying out such actions. The advantage of using a simulation of the motion is that one can experiment with variations of a maneuver before attempting to teach it to an individual. The zero-gravity motion simulation problem can be divided into two broad areas: human movement and behavior in zero-gravity, and simulation of articulated mechanisms.

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hubbard, Alexander, E-mail: ahubbard@amnh.org

    The meteoritical record shows both iron partitioning and tungsten isotopic partitioning between the matrix and chondrules. Tungsten is not abundant enough to have driven its own isotopic partitioning, but if tungsten were correlated with iron then ferromagnetic interaction grains could help explain both observations. We derive a practical parameterization for the increase in particle–particle collision rates caused by mutually attracting particle magnetic dipole moments. While the appropriate magnetic parameters remain uncertain, we show that ambient magnetic fields in protoplanetary disks are expected to be strong enough to magnetize iron metal bearing dust grains sufficiently to drive large increases in theirmore » collision rates. Such increased collision rates between iron-metal-rich grains could help preserve primordial iron and W isotopic inhomogeneities, and would help explain why the meteoritical record shows their partitioning in the solar nebula. The importance of magnetic interactions for larger grains whose growth is balanced by fragmentation is less clear and will require future laboratory or numerical studies.« less

  15. INSIDE-OUT PLANET FORMATION. III. PLANET–DISK INTERACTION AT THE DEAD ZONE INNER BOUNDARY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hu, Xiao; Tan, Jonathan C.; Chatterjee, Sourav

    The Kepler mission has discovered more than 4000 exoplanet candidates. Many of them are in systems with tightly packed inner planets. Inside-out planet formation (IOPF) has been proposed as a scenario to explain these systems. It involves sequential in situ planet formation at the local pressure maximum of a retreating dead zone inner boundary (DZIB). Pebbles accumulate at this pressure trap, which builds up a pebble ring and then a planet. The planet is expected to grow in mass until it opens a gap, which helps to both truncate pebble accretion and also induce DZIB retreat that sets the location ofmore » formation of the next planet. This simple scenario may be modified if the planet undergoes significant migration from its formation location. Thus, planet–disk interactions play a crucial role in the IOPF scenario. Here we present numerical simulations that first assess the degree of migration for planets of various masses that are forming at the DZIB of an active accretion disk, where the effective viscosity is undergoing a rapid increase in the radially inward direction. We find that torques exerted on the planet by the disk tend to trap the planet at a location very close to the initial pressure maximum where it formed. We then study gap opening by these planets to assess at what mass a significant gap is created. Finally, we present a simple model for DZIB retreat due to penetration of X-rays from the star to the disk midplane. Overall, these simulations help to quantify both the mass scale of first (“Vulcan”) planet formation and the orbital separation to the location of second planet formation.« less

  16. Inside-out Planet Formation. III. Planet-Disk Interaction at the Dead Zone Inner Boundary

    NASA Astrophysics Data System (ADS)

    Hu, Xiao; Zhu, Zhaohuan; Tan, Jonathan C.; Chatterjee, Sourav

    2016-01-01

    The Kepler mission has discovered more than 4000 exoplanet candidates. Many of them are in systems with tightly packed inner planets. Inside-out planet formation (IOPF) has been proposed as a scenario to explain these systems. It involves sequential in situ planet formation at the local pressure maximum of a retreating dead zone inner boundary (DZIB). Pebbles accumulate at this pressure trap, which builds up a pebble ring and then a planet. The planet is expected to grow in mass until it opens a gap, which helps to both truncate pebble accretion and also induce DZIB retreat that sets the location of formation of the next planet. This simple scenario may be modified if the planet undergoes significant migration from its formation location. Thus, planet-disk interactions play a crucial role in the IOPF scenario. Here we present numerical simulations that first assess the degree of migration for planets of various masses that are forming at the DZIB of an active accretion disk, where the effective viscosity is undergoing a rapid increase in the radially inward direction. We find that torques exerted on the planet by the disk tend to trap the planet at a location very close to the initial pressure maximum where it formed. We then study gap opening by these planets to assess at what mass a significant gap is created. Finally, we present a simple model for DZIB retreat due to penetration of X-rays from the star to the disk midplane. Overall, these simulations help to quantify both the mass scale of first (“Vulcan”) planet formation and the orbital separation to the location of second planet formation.

  17. Combining Self-Explaining with Computer Architecture Diagrams to Enhance the Learning of Assembly Language Programming

    ERIC Educational Resources Information Center

    Hung, Y.-C.

    2012-01-01

    This paper investigates the impact of combining self explaining (SE) with computer architecture diagrams to help novice students learn assembly language programming. Pre- and post-test scores for the experimental and control groups were compared and subjected to covariance (ANCOVA) statistical analysis. Results indicate that the SE-plus-diagram…

  18. Scaffolding Learning for Practitioner-Scholars: The Philosophy and Design of a Qualitative Research Methods Course

    ERIC Educational Resources Information Center

    Slayton, Julie; Samkian, Artineh

    2017-01-01

    We present our approach to a qualitative research methods course to prepare practitioner-scholars for their dissertation and independent research. We explain how an instructor's guide provides consistency and rigor, and in-class activities to scaffold learning, and helps faculty connect the content to students' out-of-school lives. We explain how…

  19. College Collaboration with Gifted Programs: Deaf Studies Unit (Part 2)

    ERIC Educational Resources Information Center

    Buisson, Gerald J.; Salgo, Jennifer

    2012-01-01

    The present article is the second in a 2-part series. Part 1 explained the needs of students in gifted education programs (GEPs), the concept of interest-area mentorship, and how mentors help meet gifted elementary-school students' needs in light of National Association for Gifted Children standards. Part 2 explains that the goals and standards…

  20. Understanding and Managing Learning Disabilities in Adults. Professional Practices in Adult Education and Human Resource Development Series.

    ERIC Educational Resources Information Center

    Jordan, Dale R.

    This book reviews learning disabilities (LD) in adults and makes suggestions for helping adults cope with these disabilities. Each chapter covers a type of learning disability or related syndrome or explains characteristics of the brain. Chapter 1 explains several types of specific learning disabilities that make classroom performance difficult…

  1. 78 FR 30300 - Agency Information Collection Activities; Proposed Collection; Comment Request; Implementation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ....regulations.gov to obtain a copy of the draft collection of information, submit or view public comments... helpful for preparing your comments: (i) Explain your views as clearly as possible and provide specific... and/or data you used that support your views. (iv) If you estimate potential burden or costs, explain...

  2. Parental Involvement: What Counts, Who Counts It, and Does It Help?

    ERIC Educational Resources Information Center

    Flessa, Joseph

    2008-01-01

    When asked to explain why so many urban schools show unsatisfactory results on academic or social measures, principals routinely and quickly turn to descriptions of parents. In other words, when seeking to explain why work within a school is so difficult or why reform initiatives have been unsuccessful, many principals point outside the school.…

  3. Exploring the MACH Model's Potential as a Metacognitive Tool to Help Undergraduate Students Monitor Their Explanations of Biological Mechanisms

    ERIC Educational Resources Information Center

    Trujillo, Caleb M.; Anderson, Trevor R.; Pelaez, Nancy J.

    2016-01-01

    When undergraduate biology students learn to explain biological mechanisms, they face many challenges and may overestimate their understanding of living systems. Previously, we developed the MACH model of four components used by expert biologists to explain mechanisms: Methods, Analogies, Context, and How. This study explores the implementation of…

  4. A Live Threat Violence Simulation Exercise for Psychiatric Outpatient Departments: A Valuable Aid to Training in Violence Prevention.

    PubMed

    Feinstein, Robert E; Yager, Joel

    2017-10-30

    Violence in psychiatric outpatient settings is a ubiquitous concern. This article describes the development, implementation, and evaluation of a live threat violence simulation exercise, designed to reduce the risk of future outpatient clinic violence and minimize the effects of future incidents on staff. The psychiatric outpatient clinic at the University of Colorado Hospital developed, implemented, and evaluated a 4-hour live violence threat simulation exercise as a companion to a 7-hour violence prevention program. The simulation includes an orientation, two threat simulation scenarios, three debriefings, satisfaction surveys, problem identification, action plans, and annual safety and process improvements. The authors have conducted live violence simulation exercises from 2011-2016, and have collected survey data about our annual simulation exercise from 2014-2016. Each year ≥ 52% of participants responded, and each year ≥ 90% of respondents rated the simulation as "very helpful/helpful", ≥ 86% believed themselves to be "much better/better" prepared to deal with violent episodes, and < 2% of participants experienced post-simulation side effects such as worries about past trauma; anxiety; sleep problems; increase in workplace concerns. From 2011-2016, the clinic experienced 4 major violent episodes and 36 episodes of potential violence with no staff injuries and minimal psychological sequelae to one staff member. Violence prevention efforts and the development of close police/staff relationships may have contributed to these fortunate outcomes. Satisfaction surveys suggest that the simulations are very helpful/helpful, with participants feeling much better/ better prepared to manage violence. The exercises led the authors to initiate staff safety related behavioral changes as well as physical space and safety processes improvements. The violence prevention program and simulation exercises have promoted excellent relationships with police and a consistent safety record over six years. This approach may be useful for other psychiatric outpatient departments.

  5. Prediction and Prevention of Chemical Reaction Hazards: Learning by Simulation.

    ERIC Educational Resources Information Center

    Shacham, Mordechai; Brauner, Neima; Cutlip, Michael B.

    2001-01-01

    Points out that chemical hazards are the major cause of accidents in chemical industry and describes a safety teaching approach using a simulation. Explains a problem statement on exothermic liquid-phase reactions. (YDS)

  6. Testing the World with Simulations.

    ERIC Educational Resources Information Center

    Roberts, Nancy

    1983-01-01

    Explains the three main concepts of the system dynamics approach to model building (dynamics, feedback, and systems) and the basic steps to problem solving by simulation applicable to all educational levels. Some DYNAMO commands are briefly described. (EAO)

  7. Modeling the Cerebellar Microcircuit: New Strategies for a Long-Standing Issue.

    PubMed

    D'Angelo, Egidio; Antonietti, Alberto; Casali, Stefano; Casellato, Claudia; Garrido, Jesus A; Luque, Niceto Rafael; Mapelli, Lisa; Masoli, Stefano; Pedrocchi, Alessandra; Prestori, Francesca; Rizza, Martina Francesca; Ros, Eduardo

    2016-01-01

    The cerebellar microcircuit has been the work bench for theoretical and computational modeling since the beginning of neuroscientific research. The regular neural architecture of the cerebellum inspired different solutions to the long-standing issue of how its circuitry could control motor learning and coordination. Originally, the cerebellar network was modeled using a statistical-topological approach that was later extended by considering the geometrical organization of local microcircuits. However, with the advancement in anatomical and physiological investigations, new discoveries have revealed an unexpected richness of connections, neuronal dynamics and plasticity, calling for a change in modeling strategies, so as to include the multitude of elementary aspects of the network into an integrated and easily updatable computational framework. Recently, biophysically accurate "realistic" models using a bottom-up strategy accounted for both detailed connectivity and neuronal non-linear membrane dynamics. In this perspective review, we will consider the state of the art and discuss how these initial efforts could be further improved. Moreover, we will consider how embodied neurorobotic models including spiking cerebellar networks could help explaining the role and interplay of distributed forms of plasticity. We envisage that realistic modeling, combined with closed-loop simulations, will help to capture the essence of cerebellar computations and could eventually be applied to neurological diseases and neurorobotic control systems.

  8. Modeling the Cerebellar Microcircuit: New Strategies for a Long-Standing Issue

    PubMed Central

    D’Angelo, Egidio; Antonietti, Alberto; Casali, Stefano; Casellato, Claudia; Garrido, Jesus A.; Luque, Niceto Rafael; Mapelli, Lisa; Masoli, Stefano; Pedrocchi, Alessandra; Prestori, Francesca; Rizza, Martina Francesca; Ros, Eduardo

    2016-01-01

    The cerebellar microcircuit has been the work bench for theoretical and computational modeling since the beginning of neuroscientific research. The regular neural architecture of the cerebellum inspired different solutions to the long-standing issue of how its circuitry could control motor learning and coordination. Originally, the cerebellar network was modeled using a statistical-topological approach that was later extended by considering the geometrical organization of local microcircuits. However, with the advancement in anatomical and physiological investigations, new discoveries have revealed an unexpected richness of connections, neuronal dynamics and plasticity, calling for a change in modeling strategies, so as to include the multitude of elementary aspects of the network into an integrated and easily updatable computational framework. Recently, biophysically accurate “realistic” models using a bottom-up strategy accounted for both detailed connectivity and neuronal non-linear membrane dynamics. In this perspective review, we will consider the state of the art and discuss how these initial efforts could be further improved. Moreover, we will consider how embodied neurorobotic models including spiking cerebellar networks could help explaining the role and interplay of distributed forms of plasticity. We envisage that realistic modeling, combined with closed-loop simulations, will help to capture the essence of cerebellar computations and could eventually be applied to neurological diseases and neurorobotic control systems. PMID:27458345

  9. A Relationship Between Hemisphericity and Psycho-Epistemology.

    ERIC Educational Resources Information Center

    Rancourt, Richard; Dionne, Jean-Paul

    This review of two distinct areas of research--brain research and psycho-epistemology--indicates a possible link between the two which may potentially help to identify an as yet unknown molar trait which could be responsible for divergent opinions regarding teaching and learning theories, and may help to explain differential achievement when these…

  10. New Guide Helps Industry Link with Department of Energy Labs

    Science.gov Websites

    . industry access to a "virtual" laboratory that can be tailored to meet specific requirements for Laboratory Coordinating Council. The guide explains how the DOE's Laboratory Coordinating Council gives U.S steel. Laboratory resources are available to help American companies address new opportunities, improve

  11. Conservation.

    ERIC Educational Resources Information Center

    Camp Fire Girls, Inc., New York, NY.

    The first section of this manual has been developed to help leaders and youth examine and gradually understand some of the more complex environmental factors. It helps to explain what things are where and why, why a certain project has been suggested, whether it is a practical one for a given place, and what must be known before it can be…

  12. 34 CFR 75.101 - Information in the application notice that helps an applicant apply.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false Information in the application notice that helps an... an application notice: (1) How an applicant can get an application package that contains: (i... program, an application notice for the program explains how an applicant can get the preapplication form...

  13. 34 CFR 75.101 - Information in the application notice that helps an applicant apply.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false Information in the application notice that helps an... an application notice: (1) How an applicant can get an application package that contains: (i... program, an application notice for the program explains how an applicant can get the preapplication form...

  14. 34 CFR 75.101 - Information in the application notice that helps an applicant apply.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Information in the application notice that helps an... an application notice: (1) How an applicant can get an application package that contains: (i... program, an application notice for the program explains how an applicant can get the preapplication form...

  15. 34 CFR 75.101 - Information in the application notice that helps an applicant apply.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false Information in the application notice that helps an... an application notice: (1) How an applicant can get an application package that contains: (i... program, an application notice for the program explains how an applicant can get the preapplication form...

  16. 34 CFR 75.101 - Information in the application notice that helps an applicant apply.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Information in the application notice that helps an... an application notice: (1) How an applicant can get an application package that contains: (i... program, an application notice for the program explains how an applicant can get the preapplication form...

  17. How Language Limits Our Understanding of Environmental Education.

    ERIC Educational Resources Information Center

    Bowers, Chet

    2001-01-01

    Develops a theory of metaphor that helps explain how environmental education contributes to the double bind of helping to address environmental problems while at the same time reinforcing the use of the language-thought patterns that underlie the digital phase of the Industrial Revolution that we are now entering on a global scale. (Author/SAH)

  18. Dying and Death: Helping Children Cope.

    ERIC Educational Resources Information Center

    Ledezma, Melissa L.

    This paper suggests strategies for helping children understand death. The early experiences of childhood build the foundation on which the child establishes a healthy orientation towards life and living. Grieving parents are often so upset by their own loss that they do not carefully explain death to their children. Parents may feel that the child…

  19. RCB stars from double degenerate white dwarf mergers

    NASA Astrophysics Data System (ADS)

    Staff, Jan; Wiggins, Brandon K.; Marcello, Dominic; Motl, Patrick; Clayton, Geoffrey C.

    2018-01-01

    We have conducted grid based and SPH based hydrodynamic simulations of white dwarf mergers, to investigate the role of dredge-up and mixing during the merger. The goal is to test if sufficiently little 16O can be brought up to the surface to explain the observed 16O to 18O ratio of order unity found in RCB stars. In all simulations, the total mass is ~< 1 M⊙. By initializing both the grid based and the SPH simulations with the same setup, we can compare the results from these different methods. In most of the simulations, more than 0.01 M⊙ of 16O is brought up to the surface. Hence a similar mass of 18O must be produced in order to explain the observed oxygen ratio. However,in SPH simulations where the accretor is a hybrid He/CO white dwarf, much less 16O is brought to the surface, making this an excellent candidate for the progenitor of RCB stars.

  20. Localization of one-photon state in space and Einstein-Podolsky-Rosen paradox in spontaneous parametric down conversion

    NASA Technical Reports Server (NTRS)

    Penin, A. N.; Reutova, T. A.; Sergienko, A. V.

    1992-01-01

    An experiment on one-photon state localization in space using a correlation technique in Spontaneous Parametric Down Conversion (SPDC) process is discussed. Results of measurements demonstrate an idea of the Einstein-Podolsky-Rosen (EPR) paradox for coordinate and momentum variables of photon states. Results of the experiment can be explained with the help of an advanced wave technique. The experiment is based on the idea that two-photon states of optical electromagnetic fields arising in the nonlinear process of the spontaneous parametric down conversion (spontaneous parametric light scattering) can be explained by quantum mechanical theory with the help of a single wave function.

  1. Iron and its complexation by phenolic cellular metabolites

    PubMed Central

    Chobot, Vladimir

    2010-01-01

    Iron is a transition metal that forms chelates and complexes with various organic compounds, also with phenolic plant secondary metabolites. The ligands of iron affect the redox potential of iron. Electrons may be transferred either to hydroxyl radicals, hydrogen peroxide or molecular oxygen. In the first case, oxidative stress is decreased, in the latter two cases, oxidative stress is increased. This milieu-dependent mode of action may explain the non-linear mode of action of juglone and other secondary metabolites. Attention to this phenomenon may help to explain idiosyncratic and often nonlinear effects that result in biological assays. Current chemical assays are discussed that help to explore these aspects of redox chemistry. PMID:20592800

  2. Localization of one-photon state in space and Einstein-Podolsky-Rosen paradox in spontaneous parametric down conversion

    NASA Astrophysics Data System (ADS)

    Penin, A. N.; Reutova, T. A.; Sergienko, A. V.

    1992-02-01

    An experiment on one-photon state localization in space using a correlation technique in Spontaneous Parametric Down Conversion (SPDC) process is discussed. Results of measurements demonstrate an idea of the Einstein-Podolsky-Rosen (EPR) paradox for coordinate and momentum variables of photon states. Results of the experiment can be explained with the help of an advanced wave technique. The experiment is based on the idea that two-photon states of optical electromagnetic fields arising in the nonlinear process of the spontaneous parametric down conversion (spontaneous parametric light scattering) can be explained by quantum mechanical theory with the help of a single wave function.

  3. Understanding Decision-Making in Specialized Domestic Violence Courts: Can Contemporary Theoretical Frameworks Help Guide These Decisions?

    PubMed

    Pinchevsky, Gillian M

    2016-05-22

    This study fills a gap in the literature by exploring the utility of contemporary courtroom theoretical frameworks-uncertainty avoidance, causal attribution, and focal concerns-for explaining decision-making in specialized domestic violence courts. Using data from two specialized domestic violence courts, this study explores the predictors of prosecutorial and judicial decision-making and the extent to which these factors are congruent with theoretical frameworks often used in studies of court processing. Findings suggest that these theoretical frameworks only partially help explain decision-making in the courts under study. A discussion of the findings and implications for future research is provided. © The Author(s) 2016.

  4. Breaking Frame in a Role-Play Simulation: A Language Socialization Perspective

    ERIC Educational Resources Information Center

    Schick, Laurie

    2008-01-01

    This article uses key concepts developed in frame analysis and language socialization theories to reconceptualize role-play simulation as socialization practice. The reconceptualization includes (a) an effort to explain an unexpected response to a role-play simulation on the topic of bullying and (b) a discussion regarding how this explanation…

  5. Demonstrating Computer Simulation Development for Intermediate and Middle School Applications.

    ERIC Educational Resources Information Center

    Fyffe, Darrel W.; And Others

    This discussion of the use of microcomputers to simulate complex situations for classroom use describes the advantages of using simulations, including their adaptability to many subject areas and content fields, their power to explain complex concepts, and their ability to provide variations for individual users. As an example, seven objectives…

  6. Modeling a Full Coronal Loop Observed with Hinode EIS and SDO AIA

    NASA Technical Reports Server (NTRS)

    Alexander, Caroline; Winebarger, Amy R.

    2015-01-01

    Physical parameters measured from an observation of a coronal loop from Gupta et al. (2015) using Hinode/EIS and SDO/AIA were used as input for the hydrodynamic, impulsively heating NRLSOFM 1-­d loop model. The model was run at eight different energy inputs and used the measured quantities of temperature (0.73 MK), density (10(sup 8.5)cm(sup -3) and minimum loop lifetime to evaluate the success of the model at recreating the observations. The loop was measured by us to have an unprojected length of 236 Mm and was assumed to be almost perpendicular to the solar surface (tilt of 3.5 degrees) and have a dipolar geometry. Our results show that two of our simulation runs (with input energies of 0.01 and 0.02 ergs cm(sup -3)S(sup -1) closely match the temperature/density combination exhibited by the loop observation. However, our simulated loops only remain in the temperature sensitive region of the Mg 278.4 Angstrom filter for 500 and 800 seconds respectively which is less than the 1200 seconds that the loop is observed for with EIS in order to make the temperature/density measurements over the loop's entire length. This leads us to conclude that impulsive heating of a single loop is not complex enough to explain this observation. Additional steady heating or a collection of additional strands along the line-­of-­sight would help to align the simulation with the observation.

  7. Atomistic simulation of the thermal conductivity in amorphous SiO2 matrix/Ge nanocrystal composites

    NASA Astrophysics Data System (ADS)

    Kuryliuk, Vasyl V.; Korotchenkov, Oleg A.

    2017-04-01

    We use nonequilibrium molecular dynamics computer simulations with the Tersoff potential aiming to provide a comprehensive picture of the thermal conductivity of amorphous SiO2 (a-SiO2) matrix with embedded Ge nanocrystals (nc-Ge). The modelling predicts the a-SiO2 matrix thermal conductivity in a temperature range of 50 < T < 500 K yielding a fair agreement with experiment at around room temperature. It is worth noticing that the predicted room-temperature thermal conductivity in a-SiO2 is in very good agreement with the experimental result, which is in marked contrast with the thermal conductivity calculated employing the widely used van Beest-Kramer-van Santen (BKS) potential. We show that the thermal conductivity of composite nc-Ge/a-SiO2 systems decreases steadily with increasing the volume fraction of Ge inclusions, indicative of enhanced interface scattering of phonons imposed by embedded Ge nanocrystals. We also observe that increasing the volume fractions above a certain threshold value results in a progressively increased thermal conductivity of the nanocomposite, which can be explained by increasing volume fraction of a better thermally conducting Ge. Finally, non-equilibrium molecular dynamics simulations with the Tersoff potential are promising for computing the thermal conductivity of nanocomposites based on amorphous SiO2 and can be readily scaled to more complex composite structures with embedded nanoparticles, which thus help design nanocomposites with desired thermal properties.

  8. Kinetic characteristics of debris flows as exemplified by field investigations and discrete element simulation of the catastrophic Jiweishan rockslide, China

    NASA Astrophysics Data System (ADS)

    Zou, Zongxing; Tang, Huiming; Xiong, Chengren; Su, Aijun; Criss, Robert E.

    2017-10-01

    The Jiweishan rockslide of June 5, 2009 in China provides an important opportunity to elucidate the kinetic characteristics of high-speed, long-runout debris flows. A 2D discrete element model whose mechanical parameters were calibrated using basic field data was used to simulate the kinetic behavior of this catastrophic landslide. The model output shows that the Jiweishan debris flow lasted about 3 min, released a gravitational potential energy of about 6 × 10^13 J with collisions and friction dissipating approximately equal amounts of energy, and had a maximum fragment velocity of 60-70 m/s, almost twice the highest velocity of the overall slide mass (35 m/s). Notable simulated characteristics include the high velocity and energy of the slide material, the preservation of the original positional order of the slide blocks, the inverse vertical grading of blocks, and the downslope sorting of the slide deposits. Field observations that verify these features include uprooted trees in the frontal collision area of the air-blast wave, downslope reduction of average clast size, and undamaged plants atop huge blocks that prove their lack of downslope tumbling. The secondary acceleration effect and force chains derived from the numerical model help explain these deposit features and the long-distance transport. Our back-analyzed frictions of the motion path in the PFC model provide a reference for analyzing and predicting the motion of similar geological hazards.

  9. Teaching Reinforcement of Stochastic Behavior Using Monte Carlo Simulation.

    ERIC Educational Resources Information Center

    Fox, William P.; And Others

    1996-01-01

    Explains a proposed block of instruction that would give students in industrial engineering, operations research, systems engineering, and applied mathematics the basic understanding required to begin more advanced courses in simulation theory or applications. (DDR)

  10. Numerical Simulation and Mechanical Design for TPS Electron Beam Position Monitors

    NASA Astrophysics Data System (ADS)

    Hsueh, H. P.; Kuan, C. K.; Ueng, T. S.; Hsiung, G. Y.; Chen, J. R.

    2007-01-01

    Comprehensive study on the mechanical design and numerical simulation for the high resolution electron beam position monitors are key steps to build the newly proposed 3rd generation synchrotron radiation research facility, Taiwan Photon Source (TPS). With more advanced electromagnetic simulation tool like MAFIA tailored specifically for particle accelerator, the design for the high resolution electron beam position monitors can be tested in such environment before they are experimentally tested. The design goal of our high resolution electron beam position monitors is to get the best resolution through sensitivity and signal optimization. The definitions and differences between resolution and sensitivity of electron beam position monitors will be explained. The design consideration is also explained. Prototype deign has been carried out and the related simulations were also carried out with MAFIA. The results are presented here. Sensitivity as high as 200 in x direction has been achieved in x direction at 500 MHz.

  11. Formation of specific amino acid sequences during carbodiimide-mediated condensation of amino acids in aqueous solution, and computer-simulated sequence generation

    NASA Astrophysics Data System (ADS)

    Hartmann, Jürgen; Nawroth, Thomas; Dose, Klaus

    1984-12-01

    Carbodiimide-mediated peptide synthesis in aqueous solution has been studied with respect to self-ordering of amino acids. The copolymerisation of amino acids in the presence of glutamic acid or pyroglutamic acid leads to short pyroglutamyl peptides. Without pyroglutamic acid the formation of higher polymers is favoured. The interactions of the amino acids and the peptides, however, are very complex. Therefore, the experimental results are rather difficult to explain. Some of the experimental results, however, can be explained with the aid of computer simulation programs. Regarding only the tripeptide fraction the copolymerisation of pyroGlu, Ala and Leu, as well as the simulated copolymerisation lead to pyroGlu-Ala-Leu as the main reaction product. The amino acid composition of the insoluble peptides formed during the copolymerisation of Ser, Gly, Ala, Val, Phe, Leu and Ile corresponds in part to the computer-simulated copolymerisation data.

  12. Variation of high-power aluminum-wire array Z-pinch dynamics with wire number, load mass, and array radius

    NASA Astrophysics Data System (ADS)

    Sanford, T. W. L.; Mock, R. C.; Marder, B. M.; Nash, T. J.; Spielman, R. B.; Peterson, D. L.; Roderick, N. F.; Hammer, J. H.; De Groot, J. S.; Mosher, D.; Whitney, K. G.; Apruzese, J. P.

    1997-05-01

    A systematic study of annular aluminum-wire z-pinches on the Saturn accelerator shows that the quality of the implosion, (as measured by the radial convergence, the radiated energy, pulse width, and power), increases with wire number. Radiation magnetohydrodynamic (RMHC) xy simulations suggest that the implosion transitions from that of individual wire plasmas to that of a continuous plasma shell when the interwire spacing is reduced below ˜1.4 mm. In this "plasma-shell regime," many of the global radiation and plasma characteristics are in agreement with those simulated by 2D-RMHC rz simulations. In this regime, measured changes in the radiation pulse width with variations in load mass and array radius are consistent with the simulations and are explained by the development of 2D fluid motion in the rz plane. Associated variations in the K-shell yield are qualitatively explained by simple radiation-scaling models.

  13. The impact of help seeking on individual task performance: the moderating effect of help seekers' logics of action.

    PubMed

    Geller, Dvora; Bamberger, Peter A

    2012-03-01

    Drawing from achievement-goal theory and the social psychological literature on help seeking, we propose that it is the variance in the logic underpinning employees' help seeking that explains divergent findings regarding the relationship between help seeking and task performance. Using a sample of 110 newly hired customer contact employees, a prospective study design, and archival performance data, we found no evidence of a hypothesized main effect of help seeking on performance. However, we did find that the help seeking-performance relationship was conditioned by the degree to which help seekers endorse 2 alternative help-seeking logics (autonomous vs. dependent logic) such that the level of help seeking is more strongly related to performance among those either more strongly endorsing an autonomous help-seeking logic or more weakly endorsing a dependent help-seeking logic.

  14. Assessing Model Data Fit of Unidimensional Item Response Theory Models in Simulated Data

    ERIC Educational Resources Information Center

    Kose, Ibrahim Alper

    2014-01-01

    The purpose of this paper is to give an example of how to assess the model-data fit of unidimensional IRT models in simulated data. Also, the present research aims to explain the importance of fit and the consequences of misfit by using simulated data sets. Responses of 1000 examinees to a dichotomously scoring 20 item test were simulated with 25…

  15. Development and validation of the Simulation Learning Effectiveness Scale for nursing students.

    PubMed

    Pai, Hsiang-Chu

    2016-11-01

    To develop and validate the Simulation Learning Effectiveness Scale, which is based on Bandura's social cognitive theory. A simulation programme is a significant teaching strategy for nursing students. Nevertheless, there are few evidence-based instruments that validate the effectiveness of simulation learning in Taiwan. This is a quantitative descriptive design. In Study 1, a nonprobability convenience sample of 151 student nurses completed the Simulation Learning Effectiveness Scale. Exploratory factor analysis was used to examine the factor structure of the instrument. In Study 2, which involved 365 student nurses, confirmatory factor analysis and structural equation modelling were used to analyse the construct validity of the Simulation Learning Effectiveness Scale. In Study 1, exploratory factor analysis yielded three components: self-regulation, self-efficacy and self-motivation. The three factors explained 29·09, 27·74 and 19·32% of the variance, respectively. The final 12-item instrument with the three factors explained 76·15% of variance. Cronbach's alpha was 0·94. In Study 2, confirmatory factor analysis identified a second-order factor termed Simulation Learning Effectiveness Scale. Goodness-of-fit indices showed an acceptable fit overall with the full model (χ 2 /df (51) = 3·54, comparative fit index = 0·96, Tucker-Lewis index = 0·95 and standardised root-mean-square residual = 0·035). In addition, teacher's competence was found to encourage learning, and self-reflection and insight were significantly and positively associated with Simulation Learning Effectiveness Scale. Teacher's competence in encouraging learning also was significantly and positively associated with self-reflection and insight. Overall, theses variable explained 21·9% of the variance in the student's learning effectiveness. The Simulation Learning Effectiveness Scale is a reliable and valid means to assess simulation learning effectiveness for nursing students. The Simulation Learning Effectiveness Scale can be used to examine nursing students' learning effectiveness and serve as a basis to improve student's learning efficiency through simulation programmes. Future implementation research that focuses on the relationship between learning effectiveness and nursing competence in nursing students is recommended. © 2016 John Wiley & Sons Ltd.

  16. Microwave Polarized Signatures Generated within Cloud Systems: SSM/I Observations Interpreted with Radiative Transfer Simulations

    NASA Technical Reports Server (NTRS)

    Prigent, Catherine; Pardo, Juan R.; Mishchenko, Michael I.; Rossow, Willaim B.; Hansen, James E. (Technical Monitor)

    2001-01-01

    Special Sensor Microwave /Imager (SSM/I) observations in cloud systems are studied over the tropics. Over optically thick cloud systems, presence of polarized signatures at 37 and 85 GHz is evidenced and analyzed with the help of cloud top temperature and optical thickness extracted from visible and IR satellite observations. Scattering signatures at 85 GHz (TbV(85) less than or = 250 K) are associated with polarization differences greater than or = 6 K, approx. 50%, of the time over ocean and approx. 40% over land. In addition. over thick clouds the polarization difference at 37 GHz is rarely negligible. The polarization differences at 37 and 85 GHz do not stem from the surface but are generated in regions of relatively homogeneous clouds having high liquid water content. To interpret the observations, a radiative transfer model that includes the scattering by non-spherical particles is developed. based on the T-matrix approach and using the doubling and adding method. In addition to handling randomly and perfectly oriented particles, this model can also simulate the effect of partial orientation of the hydrometeors. Microwave brightness temperatures are simulated at SSM/I frequencies and are compared with the observations. Polarization differences of approx. 2 K can be simulated at 37 GHz over a rain layer, even using spherical drops. The polarization difference is larger for oriented non-spherical particles. The 85 GHz simulations are very sensitive to the ice phase of the cloud. Simulations with spherical particles or with randomly oriented non-spherical ice particles cannot replicate the observed polarization differences. However, with partially oriented non-spherical particles, the observed polarized signatures at 85 GHz are explained, and the sensitivity of the scattering characteristics to the particle size, asphericity, and orientation is analyzed. Implications on rain and ice retrievals are discussed.

  17. Saving robots improves laparoscopic performance: transfer of skills from a serious game to a virtual reality simulator.

    PubMed

    IJgosse, Wouter M; van Goor, Harry; Luursema, Jan-Maarten

    2018-01-18

    Residents find it hard to commit to structural laparoscopic skills training. Serious gaming has been proposed as a solution on the premise that it is effective and more motivating than traditional simulation. We establish construct validity for the laparoscopic serious game Underground by comparing laparoscopic simulator performance for a control group and an Underground training group. A four-session laparoscopic basic skills course is part of the medical master students surgical internship at the Radboud University Medical Centre. Four cohorts, representing 107 participants, were assigned to either the Underground group or the control group. The control group trained on the FLS video trainer and the LapSim virtual reality simulator for four sessions. The Underground group played Underground for three sessions followed by a transfer session on the FLS video trainer and the LapSim. To assess the effect of engaging in serious gameplay on performance on two validated laparoscopic simulators, initial performance on the FLS video trainer and the LapSim was compared between the control group (first session) and the Underground group (fourth session). We chose task duration as a proxy for laparoscopic performance. The Underground group outperformed the control group on all three LapSim tasks: Camera navigation F(1) = 12.71, p < .01; Instrument navigation F(1) = 8.04, p < .01; and Coordination F(1) = 6.36, p = .01. There was no significant effect of playing Underground for performance on the FLS video trainer Peg Transfer task, F(1) = 0.28, p = .60. We demonstrated skills transfer between a serious game and validated laparoscopic simulator technology. Serious gaming may become a valuable, cost-effective addition to the skillslab, if transfer to the operating room can be established. Additionally, we discuss sources of transferable skills to help explain our and previous findings.

  18. Hamstring Muscle Fatigue and Central Motor Output during a Simulated Soccer Match

    PubMed Central

    Marshall, Paul W. M.; Lovell, Ric; Jeppesen, Gitte K.; Andersen, Kristoffer; Siegler, Jason C.

    2014-01-01

    Purpose To examine changes in hamstring muscle fatigue and central motor output during a 90-minute simulated soccer match, and the concomitant changes in hamstring maximal torque and rate of torque development. Method Eight amateur male soccer players performed a 90-minute simulated soccer match, with measures performed at the start of and every 15-minutes during each half. Maximal torque (Nm) and rate of torque development (RTD; Nm.s–1) were calculated from maximal isometric knee flexor contractions performed at 10° of flexion. Hamstring peripheral fatigue was assessed from changes in the size and shape of the resting twitch (RT). Hamstring central motor output was quantified from voluntary activation (%) and normalized biceps femoris (BF) and medial hamstrings (MH) electromyographic amplitudes (EMG/M). Results Maximal torque was reduced at 45-minutes by 7.6±9.4% (p<0.05). RTD in time intervals of 0–25, 0–50, and 0–75 ms post-contraction onset were reduced after 15-minutes in the first-half between 29.6 to 46.2% (p<0.05), and were further reduced at the end of the second-half (p<0.05). Maximal EMG/M was reduced for biceps femoris only concomitant to the time-course of reductions in maximal torque (p = 0.007). The rate of EMG rise for BF and MH was reduced in early time periods (0–75 ms) post-contraction onset (p<0.05). No changes were observed for the size and shape of the RT, indicating no hamstring peripheral fatigue. Conclusion Centrally mediated reductions in maximal torque and rate of torque development provide insight into factors that may explain hamstring injury risk during soccer. Of particular interest were early reductions during the first-half of hamstring rate of torque development, and the decline in maximal EMG/M of biceps femoris in the latter stages of the half. These are important findings that may help explain why the hamstrings are particularly vulnerable to strain injury during soccer. PMID:25047547

  19. Why humans might help strangers

    PubMed Central

    Raihani, Nichola J.; Bshary, Redouan

    2015-01-01

    Humans regularly help strangers, even when interactions are apparently unobserved and unlikely to be repeated. Such situations have been simulated in the laboratory using anonymous one-shot games (e.g., prisoner’s dilemma) where the payoff matrices used make helping biologically altruistic. As in real-life, participants often cooperate in the lab in these one-shot games with non-relatives, despite that fact that helping is under negative selection under these circumstances. Two broad explanations for such behavior prevail. The “big mistake” or “mismatch” theorists argue that behavior is constrained by psychological mechanisms that evolved predominantly in the context of repeated interactions with known individuals. In contrast, the cultural group selection theorists posit that humans have been selected to cooperate in anonymous one-shot interactions due to strong between-group competition, which creates interdependence among in-group members. We present these two hypotheses before discussing alternative routes by which humans could increase their direct fitness by cooperating with strangers under natural conditions. In doing so, we explain why the standard lab games do not capture real-life in various important aspects. First, asymmetries in the cost of perceptual errors regarding the context of the interaction (one-shot vs. repeated; anonymous vs. public) might have selected for strategies that minimize the chance of making costly behavioral errors. Second, helping strangers might be a successful strategy for identifying other cooperative individuals in the population, where partner choice can turn strangers into interaction partners. Third, in contrast to the assumptions of the prisoner’s dilemma model, it is possible that benefits of cooperation follow a non-linear function of investment. Non-linear benefits result in negative frequency dependence even in one-shot games. Finally, in many real-world situations individuals are able to parcel investments such that a one-shot interaction is turned into a repeated game of many decisions. PMID:25750619

  20. Qualitative Assessment of a 3D Simulation Program: Faculty, Students, and Bio-Organic Reaction Animations

    ERIC Educational Resources Information Center

    Günersel, Adalet B.; Fleming, Steven A.

    2013-01-01

    Research shows that computer-based simulations and animations are especially helpful in fields such as chemistry where concepts are abstract and cannot be directly observed. Bio-Organic Reaction Animations (BioORA) is a freely available 3D visualization software program developed to help students understand the chemistry of biomolecular events.…

  1. Explaining the Gender Gap in Help to Parents: The Importance of Employment

    ERIC Educational Resources Information Center

    Sarkisian, Natalia; Gerstel, Naomi

    2004-01-01

    Although it is well established that adult daughters spend more time giving assistance to their parents than do sons, the sources of this gender gap are not well understood. This paper asks: To what extent can this gap be explained by structural variation, especially the different rates of employment and kinds of jobs that women and men tend to…

  2. Superintendent Suspensions: Elementary and Junior High School Students. A Guide for Parents and Students.

    ERIC Educational Resources Information Center

    Advocates for Children of New York, Inc., Long Island City.

    This guide has been written to help parents represent their children at New York City Board of Education hearings. The guide explains the rights of parents and children and explains the steps a parent should take in representing the child. It only applies to regular education junior high, intermediate, and elementary school suspensions. Sections…

  3. Explaining the Positive Relationship Between Fourth-Grade Children's Body Mass Index and Energy Intake at School-Provided Meals (Breakfast and Lunch)

    ERIC Educational Resources Information Center

    Guinn, Caroline H.; Baxter, Suzanne D.; Royer, Julie A.; Hitchcock, David B.

    2013-01-01

    Background: A 2010 publication showed a positive relationship between children's body mass index (BMI) and energy intake at school-provided meals (as assessed by direct meal observations). To help explain that relationship, we investigated 7 outcome variables concerning aspects of school-provided meals: energy content of items selected, number of…

  4. The Role of Loneliness in the Relationship between Anxiety and Depression in Clinical and School-Based Youth

    ERIC Educational Resources Information Center

    Ebesutani, Chad; Fierstein, Matthew; Viana, Andres G.; Trent, Lindsay; Young, John; Sprung, Manuel

    2015-01-01

    Identifying mechanisms that explain the relationship between anxiety and depression are needed. The Tripartite Model is one model that has been proposed to help explain the association between these two problems, positing a shared component called negative affect. The objective of the present study was to examine the role of loneliness in relation…

  5. A role for relaxed selection in the evolution of the language capacity

    PubMed Central

    Deacon, Terrence W.

    2010-01-01

    Explaining the extravagant complexity of the human language and our competence to acquire it has long posed challenges for natural selection theory. To answer his critics, Darwin turned to sexual selection to account for the extreme development of language. Many contemporary evolutionary theorists have invoked incredibly lucky mutation or some variant of the assimilation of acquired behaviors to innate predispositions in an effort to explain it. Recent evodevo approaches have identified developmental processes that help to explain how complex functional synergies can evolve by Darwinian means. Interestingly, many of these developmental mechanisms bear a resemblance to aspects of Darwin's mechanism of natural selection, often differing only in one respect (e.g., form of duplication, kind of variation, competition/cooperation). A common feature is an interplay between processes of stabilizing selection and processes of relaxed selection at different levels of organism function. These may play important roles in the many levels of evolutionary process contributing to language. Surprisingly, the relaxation of selection at the organism level may have been a source of many complex synergistic features of the human language capacity, and may help explain why so much language information is “inherited” socially. PMID:20445088

  6. Explaining the heterogeneity of functional connectivity findings in multiple sclerosis: An empirically informed modeling study.

    PubMed

    Tewarie, Prejaas; Steenwijk, Martijn D; Brookes, Matthew J; Uitdehaag, Bernard M J; Geurts, Jeroen J G; Stam, Cornelis J; Schoonheim, Menno M

    2018-06-01

    To understand the heterogeneity of functional connectivity results reported in the literature, we analyzed the separate effects of grey and white matter damage on functional connectivity and networks in multiple sclerosis. For this, we employed a biophysical thalamo-cortical model consisting of interconnected cortical and thalamic neuronal populations, informed and amended by empirical diffusion MRI tractography data, to simulate functional data that mimic neurophysiological signals. Grey matter degeneration was simulated by decreasing within population connections and white matter degeneration by lowering between population connections, based on lesion predilection sites in multiple sclerosis. For all simulations, functional connectivity and functional network organization are quantified by phase synchronization and network integration, respectively. Modeling results showed that both cortical and thalamic grey matter damage induced a global increase in functional connectivity, whereas white matter damage induced an initially increased connectivity followed by a global decrease. Both white and especially grey matter damage, however, induced a decrease in network integration. These empirically informed simulations show that specific topology and timing of structural damage are nontrivial aspects in explaining functional abnormalities in MS. Insufficient attention to these aspects likely explains contradictory findings in multiple sclerosis functional imaging studies so far. © 2018 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

  7. Modelling and Simulation of the Dynamics of the Antigen-Specific T Cell Response Using Variable Structure Control Theory.

    PubMed

    Anelone, Anet J N; Spurgeon, Sarah K

    2016-01-01

    Experimental and mathematical studies in immunology have revealed that the dynamics of the programmed T cell response to vigorous infection can be conveniently modelled using a sigmoidal or a discontinuous immune response function. This paper hypothesizes strong synergies between this existing work and the dynamical behaviour of engineering systems with a variable structure control (VSC) law. These findings motivate the interpretation of the immune system as a variable structure control system. It is shown that dynamical properties as well as conditions to analytically assess the transition from health to disease can be developed for the specific T cell response from the theory of variable structure control. In particular, it is shown that the robustness properties of the specific T cell response as observed in experiments can be explained analytically using a VSC perspective. Further, the predictive capacity of the VSC framework to determine the T cell help required to overcome chronic Lymphocytic Choriomeningitis Virus (LCMV) infection is demonstrated. The findings demonstrate that studying the immune system using variable structure control theory provides a new framework for evaluating immunological dynamics and experimental observations. A modelling and simulation tool results with predictive capacity to determine how to modify the immune response to achieve healthy outcomes which may have application in drug development and vaccine design.

  8. MHD SIMULATIONS OF CORONAL SUPRA-ARCADE DOWNFLOWS INCLUDING ANISOTROPIC THERMAL CONDUCTION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zurbriggen, E.; Costa, A.; Schneiter, M.

    2016-11-20

    Coronal supra-arcade downflows (SADs) are observed as dark trails descending toward hot turbulent-fan-shaped regions. Due to the large temperature values and gradients in these fan regions, the thermal conduction (TC) should be very efficient. While several models have been proposed to explain the triggering and the evolution of SADs, none of these scenarios address a systematic consideration of TC. Thus, we accomplish this task numerically simulating the evolution of SADs within this framework. That is, SADs are conceived as voided (subdense) cavities formed by nonlinear waves triggered by downflowing bursty localized reconnection events in a perturbed hot fan. We generatemore » a properly turbulent fan, obtained by a stirring force that permits control of the energy and vorticity input in the medium where SADs develop. We include anisotropic TC and consider plasma properties consistent with observations. Our aim is to study whether it is possible to prevent SADs from vanishing by thermal diffusion. We find that this will be the case, depending on the turbulence parameters, in particular if the magnetic field lines are able to envelope the voided cavities, thermally isolating them from the hot environment. Velocity shear perturbations that are able to generate instabilities of the Kelvin–Helmholtz type help to produce magnetic islands, extending the lifetime of SADs.« less

  9. Amplification of perpendicular and parallel magnetic fields by cosmic ray currents

    NASA Astrophysics Data System (ADS)

    Matthews, J. H.; Bell, A. R.; Blundell, K. M.; Araudo, A. T.

    2017-08-01

    Cosmic ray (CR) currents through magnetized plasma drive strong instabilities producing amplification of the magnetic field. This amplification helps explain the CR energy spectrum as well as observations of supernova remnants and radio galaxy hotspots. Using magnetohydrodynamic simulations, we study the behaviour of the non-resonant hybrid (NRH) instability (also known as the Bell instability) in the case of CR currents perpendicular and parallel to the initial magnetic field. We demonstrate that extending simulations of the perpendicular case to 3D reveals a different character to the turbulence from that observed in 2D. Despite these differences, in 3D the perpendicular NRH instability still grows exponentially far into the non-linear regime with a similar growth rate to both the 2D perpendicular and 3D parallel situations. We introduce some simple analytical models to elucidate the physical behaviour, using them to demonstrate that the transition to the non-linear regime is governed by the growth of thermal pressure inside dense filaments at the edges of the expanding loops. We discuss our results in the context of supernova remnants and jets in radio galaxies. Our work shows that the NRH instability can amplify magnetic fields to many times their initial value in parallel and perpendicular shocks.

  10. Development and validation of a computational model to study the effect of foot constraint on ankle injury due to external rotation.

    PubMed

    Wei, Feng; Hunley, Stanley C; Powell, John W; Haut, Roger C

    2011-02-01

    Recent studies, using two different manners of foot constraint, potted and taped, document altered failure characteristics in the human cadaver ankle under controlled external rotation of the foot. The posterior talofibular ligament (PTaFL) was commonly injured when the foot was constrained in potting material, while the frequency of deltoid ligament injury was higher for the taped foot. In this study an existing multibody computational modeling approach was validated to include the influence of foot constraint, determine the kinematics of the joint under external foot rotation, and consequently obtain strains in various ligaments. It was hypothesized that the location of ankle injury due to excessive levels of external foot rotation is a function of foot constraint. The results from this model simulation supported this hypothesis and helped to explain the mechanisms of injury in the cadaver experiments. An excessive external foot rotation might generate a PTaFL injury for a rigid foot constraint, and an anterior deltoid ligament injury for a pliant foot constraint. The computational models may be further developed and modified to simulate the human response for different shoe designs, as well as on various athletic shoe-surface interfaces, so as to provide a computational basis for optimizing athletic performance with minimal injury risk.

  11. Effects of Stretching Speed on Mechanical Rupture of Phospholipid/Cholesterol Bilayers: Molecular Dynamics Simulation

    PubMed Central

    Shigematsu, Taiki; Koshiyama, Kenichiro; Wada, Shigeo

    2015-01-01

    Rupture of biological cell membrane under mechanical stresses is critical for cell viability. It is triggered by local rearrangements of membrane molecules. We investigated the effects of stretching speed on mechanical rupture of phospholipid/cholesterol bilayers using unsteady molecular dynamics simulations. We focused on pore formation, the trigger of rupture, in a 40 mol% cholesterol-including bilayer. The unsteady stretching was modeled by proportional and temporal scaling of atom positions at stretching speeds from 0.025 to 30 m/s. The effects of the stretching speed on the critical areal strain, where the pore forms, is composed of two regimes. At low speeds (<1.0 m/s), the critical areal strain is insensitive to speed, whereas it significantly increases at higher speeds. Also, the strain is larger than that of a pure bilayer, regardless of the stretching speeds, which qualitatively agrees with available experimental data. Transient recovery of the cholesterol and phospholipid molecular orientations was evident at lower speeds, suggesting the formation of a stretch-induced interdigitated gel-like phase. However, this recovery was not confirmed at higher speeds or for the pure bilayer. The different responses of the molecular orientations may help explain the two regimes for the effect of stretching speed on pore formation. PMID:26471872

  12. Understanding the interactions of different substrates with wild-type and mutant acylaminoacyl peptidase using molecular dynamics simulations.

    PubMed

    Zhu, Jingxuan; Wang, Yan; Li, Xin; Han, Weiwei; Zhao, Li

    2017-12-20

    Acylaminoacylpeptidase (AAP) belongs to peptidase protein family, which can degrade amyloid β-peptide forms in the brains of patients, and hence leads to Alzheimer's disease. And so, AAP is considered to be a novel target in the design of drugs against Alzheimer's disease. In this investigation, six molecular dynamics simulations were used to find that the interaction between the wild-type and R526V AAP with two different substrates (p-nitrophenylcaprylate and Ac-Leu-p-nitroanilide). Our results were as follows: firstly, Ac-Leu-p-nitroanilide bound to R526V AAP to form a more disordered loop (residues 552-562) in the α/β-hydrolase fold like of AAP, which caused an open and inactive AAP domain form, secondly, binding p-nitrophenylcaprylate and Ac-Leu-p-nitroanilide to AAP can decrease the flexibility of residues 225-250, 260-270, and 425-450, in which the ordered secondary structures may contain the suitable geometrical structure and so it is useful to serine attack. Our theoretical results showed that the binding of the two substrates can induce specific conformational changes responsible for the diverse AAP catalytic specificity. These theoretical substrate-induced structural diversities can help explain the abilities of AAPs to recognize and hydrolyze extremely different substrates.

  13. Selectivity and self-diffusion of CO2 and H2 in a mixture on a graphite surface

    PubMed Central

    Trinh, Thuat T.; Vlugt, Thijs J. H.; Hägg, May-Britt; Bedeaux, Dick; Kjelstrup, Signe

    2013-01-01

    We performed classical molecular dynamics (MD) simulations to understand the mechanism of adsorption from a gas mixture of CO2 and H2 (mole fraction of CO2 = 0.30) and diffusion along a graphite surface, with the aim to help enrich industrial off-gases in CO2, separating out H2. The temperature of the system in the simulation covered typical industrial conditions for off-gas treatment (250–550 K). The interaction energy of single molecules CO2 or H2 on graphite surface was calculated with classical force fields (FFs) and with Density Functional Theory (DFT). The results were in good agreement. The binding energy of CO2 on graphite surface is three times larger than that of H2. At lower temperatures, the selectivity of CO2 over H2 is five times larger than at higher temperatures. The position of the dividing surface was used to explain how the adsorption varies with pore size. In the temperature range studied, the self-diffusion coefficient of CO2 is always smaller than of H2. The temperature variation of the selectivities and the self-diffusion coefficient imply that the carbon molecular sieve membrane can be used for gas enrichment of CO2. PMID:24790965

  14. Inhibition Kinetics and Emodin Cocrystal Structure of a Type II Polyketide Ketoreductase†,‡

    PubMed Central

    Korman, Tyler Paz; Tan, Yuhong; Wong, Justin; Luo, Rui; Tsai, Shiou-Chuan

    2008-01-01

    Type II polyketides are a class of natural products that include pharmaceutically important aromatic compounds such as the antibiotic tetracycline and antitumor compound doxorubicin. The type II polyketide synthase (PKS) is a complex consisting of 5–10 standalone domains homologous to fatty acid synthase (FAS). Polyketide ketoreductase (KR) provides regio- and stereochemical diversity during the reduction. How the type II polyketide KR specifically reduces only the C9 carbonyl group is not well understood. The cocrystal structures of actinorhodin polyketide ketoreductase (actKR) bound with NADPH or NADP+ and the inhibitor emodin were solved with the wild type and P94L mutant of actKR, revealing the first observation of a bent p-quinone in an enzyme active site. Molecular dynamics simulation help explain the origin of the bent geometry. Extensive screening for in vitro substrates shows that unlike FAS KR, the actKR prefers bicyclic substrates. Inhibition kinetics indicate that actKR follows an ordered Bi Bi mechanism. Together with docking simulations that identified a potential phosphopantetheine binding groove, the structural and functional studies reveal that the C9 specificity is a result of active site geometry and substrate ring constraints. The results lay the foundation for the design of novel aromatic polyketide natural products with different reduction patterns. PMID:18205400

  15. Inhibition Kinetics And Emodin Cocrystal Structure of a Type II Polyketide Ketoreductase

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Korman, T.P.; Tan, Y.-H.; Wong, J.

    Type II polyketides are a class of natural products that include pharmaceutically important aromatic compounds such as the antibiotic tetracycline and antitumor compound doxorubicin. The type II polyketide synthase (PKS) is a complex consisting of 5-10 standalone domains homologous to fatty acid synthase (FAS). Polyketide ketoreductase (KR) provides regio- and stereochemical diversity during the reduction. How the type II polyketide KR specifically reduces only the C9 carbonyl group is not well understood. The cocrystal structures of actinorhodin polyketide ketoreductase (actKR) bound with NADPH or NADP{sup +} and the inhibitor emodin were solved with the wild type and P94L mutant ofmore » actKR, revealing the first observation of a bent p-quinone in an enzyme active site. Molecular dynamics simulation help explain the origin of the bent geometry. Extensive screening for in vitro substrates shows that unlike FAS KR, the actKR prefers bicyclic substrates. Inhibition kinetics indicate that actKR follows an ordered Bi Bi mechanism. Together with docking simulations that identified a potential phosphopantetheine binding groove, the structural and functional studies reveal that the C9 specificity is a result of active site geometry and substrate ring constraints. The results lay the foundation for the design of novel aromatic polyketide natural products with different reduction patterns.« less

  16. A study of water uptake by selected superdisintegrants from the sub-molecular to the particulate level.

    PubMed

    Barmpalexis, P; Syllignaki, P; Kachrimanis, K

    2018-06-01

    Water diffusion through the matrix of three superdisintegrants, namely sodium starch glycolate (SSG), croscarmellose sodium (cCMC-Na) and crospovidone (cPVP), was studied at the sub-molecular level using Attenuated Total Reflectance (ATR)-FTIR spectroscopy and molecular dynamics simulations, and the results were correlated to water uptake studies conducted at the particulate level using Parallel Exponential Kinetics (PEK) modeling in dynamic moisture sorption studies and optical microscopy. ATR-FTIR studies indicated that water diffuses inside cPVP by a single fast acting process, while in SSG and cCMC-Na, a slow and a fast process acting simultaneously, were identified. The same pattern regarding the rate of water uptake for all superdisintegrants was found also at the particulate level by PEK modeling. Moreover, molecular dynamics simulation helped elucidate the hydrogen bonding patterns formed between water-SSG and water-cCMC-Na, mainly via their carboxylic oxygen atoms and secondarily via their hydroxyl groups, while cPVP formed hydrogen bonds only through carbonyl oxygen. Finally, cPVP chains showed significant flexibility during hydration, while cCMC-Na and SSG chains retain their conformation to some extent, explaining the extensive swelling observed also at the particulate level by optical microscopy hydration studies.

  17. Simulation of High-Latitude Hydrological Processes in the Torne-Kalix Basin: PILPS Phase 2(e). 3; Equivalent Model Representation and Sensitivity Experiments

    NASA Technical Reports Server (NTRS)

    Bowling, Laura C.; Lettenmaier, Dennis P.; Nijssen, Bart; Polcher, Jan; Koster, Randal D.; Lohmann, Dag; Houser, Paul R. (Technical Monitor)

    2002-01-01

    The Project for Intercomparison of Land Surface Parameterization Schemes (PILPS) Phase 2(e) showed that in cold regions the annual runoff production in Land Surface Schemes (LSSs) is closely related to the maximum snow accumulation, which in turn is controlled in large part by winter sublimation. To help further explain the relationship between snow cover, turbulent exchanges and runoff production, a simple equivalent model-(SEM) was devised to reproduce the seasonal and annual fluxes simulated by 13 LSSs that participated in PILPS Phase 2(e). The design of the SEM relates the annual partitioning of precipitation and energy in the LSSs to three primary parameters: snow albedo, effective aerodynamic resistance and evaporation efficiency. Isolation of each of the parameters showed that the annual runoff production was most sensitive to the aerodynamic resistance. The SEM was somewhat successful in reproducing the observed LSS response to a decrease in shortwave radiation and changes in wind speed forcings. SEM parameters derived from the reduced shortwave forcings suggested that increased winter stability suppressed turbulent heat fluxes over snow. Because winter sensible heat fluxes were largely negative, reductions in winter shortwave radiation imply an increase in annual average sensible heat.

  18. Influence of specimen thickness on the fatigue behavior of notched steel plates subjected to laser shock peening

    NASA Astrophysics Data System (ADS)

    Granados-Alejo, V.; Rubio-González, C.; Vázquez-Jiménez, C. A.; Banderas, J. A.; Gómez-Rosas, G.

    2018-05-01

    The influence of specimen thickness on the fatigue crack initiation of 2205 duplex stainless steel notched specimens subjected to laser shock peening (LSP) was investigated. The purpose was to examine the effectiveness of LSP on flat components with different thicknesses. For the LSP treatment a Nd:YAG pulsed laser operating at 10 Hz with 1064 nm of wavelength was used; pulse density was 2500 pulses/cm2. The LSP setup was the waterjet arrangement without sample coating. Residual stress distribution as a function of depth was determined by the hole drilling method. Notched specimens 2, 3 and 4 mm thick were LSP treated on both faces and then fatigue loading was applied with R = 0.1. Experimental fatigue lives were compared with life predictions from finite element simulation. A good comparison of the predicted and experimental fatigue lives was observed. LSP finite element simulation helps in explaining the influence of thickness on fatigue lives in terms of equivalent plastic strain distribution variations associated with the change in thickness. It is demonstrated that specimen size effect is an important issue in applying LSP on real components. Reducing the specimen thickness, the fatigue life improvement induced by LSP is significantly increased. Fatigue life extension up to 300% is observed on thin specimens with LSP.

  19. Evolution of Size and Chemical Composition of Copper Concentrate Particles Oxidized Under Simulated Flash Smelting Conditions

    NASA Astrophysics Data System (ADS)

    Pérez-Tello, Manuel; Parra-Sánchez, Víctor R.; Sánchez-Corrales, Víctor M.; Gómez-Álvarez, Agustín; Brown-Bojórquez, Francisco; Parra-Figueroa, Roberto A.; Balladares-Varela, Eduardo R.; Araneda-Hernández, Eugenia A.

    2018-04-01

    An experimental study was conducted to elucidate the evolution of size and chemical composition of La Caridad copper concentrate particles during oxidation under simulated flash smelting conditions. Input variables tested included particle size and oxygen concentration in the process gas. The response variables included the size distributions, chemical composition, and morphology of the reacted particles at seven locations along a laboratory reactor. Particles with initial size < 45 µm contained mostly chalcopyrite, they increased their mean size and decreased the amount of dust in the population during oxidation. This was explained by a reaction path involving rapid melting followed by collision and coalescence of reacting droplets during flight. Particles with sizes > 45 µm contained varying amounts of chalcopyrite and pyrite, and tended to either maintain or decrease their mean size upon oxidation. When size reduction was observed, dust was produced because of fragmentation, and the particles showed no evidence of collisions during flight. The main oxidation products detected in the particles consisted of matte, cuprospinel, and magnetite. A plot of the mean size divided by the mean size in the feed against the fraction of sulfur eliminated generalized the experimental data so far reported in the literature, and helped identify the reaction path followed by the particles.

  20. Using negative emotional feedback to modify risky behavior of young moped riders.

    PubMed

    Megías, Alberto; Cortes, Abilio; Maldonado, Antonio; Cándido, Antonio

    2017-05-19

    The aim of this research was to investigate whether the use of messages with negative emotional content is effective in promoting safe behavior of moped riders and how exactly these messages modulate rider behavior. Participants received negative feedback when performing risky behaviors using a computer task. The effectiveness of this treatment was subsequently tested in a riding simulator. The results demonstrated how riders receiving negative feedback had a lower number of traffic accidents than a control group. The reduction in accidents was accompanied by a set of changes in the riding behavior. We observed a lower average speed and greater respect for speed limits. Furthermore, analysis of the steering wheel variance, throttle variance, and average braking force provided evidence for a more even and homogenous riding style. This greater abidance of traffic regulations and friendlier riding style could explain some of the causes behind the reduction in accidents. The use of negative emotional feedback in driving schools or advanced rider assistance systems could enhance riding performance, making riders aware of unsafe practices and helping them to establish more accurate riding habits. Moreover, the combination of riding simulators and feedback-for example, in the training of novice riders and traffic offenders-could be an efficient tool to improve their hazard perception skills and promote safer behaviors.

  1. Global lake evaporation accelerated by changes in surface energy allocation in a warmer climate

    NASA Astrophysics Data System (ADS)

    Wang, Wei; Lee, Xuhui; Xiao, Wei; Liu, Shoudong; Schultz, Natalie; Wang, Yongwei; Zhang, Mi; Zhao, Lei

    2018-06-01

    Lake evaporation is a sensitive indicator of the hydrological response to climate change. Variability in annual lake evaporation has been assumed to be controlled primarily by the incoming surface solar radiation. Here we report simulations with a numerical model of lake surface fluxes, with input data based on a high-emissions climate change scenario (Representative Concentration Pathway 8.5). In our simulations, the global annual lake evaporation increases by 16% by the end of the century, despite little change in incoming solar radiation at the surface. We attribute about half of this projected increase to two effects: periods of ice cover are shorter in a warmer climate and the ratio of sensible to latent heat flux decreases, thus channelling more energy into evaporation. At low latitudes, annual lake evaporation is further enhanced because the lake surface warms more slowly than the air, leading to more long-wave radiation energy available for evaporation. We suggest that an analogous change in the ratio of sensible to latent heat fluxes in the open ocean can help to explain some of the spread among climate models in terms of their sensitivity of precipitation to warming. We conclude that an accurate prediction of the energy balance at the Earth's surface is crucial for evaluating the hydrological response to climate change.

  2. An Authentic RFLP Lab for High School or College Biology Students.

    ERIC Educational Resources Information Center

    Guilfoile, Patrick G.; Plum, Stephen

    1998-01-01

    Explains how students can perform an alternative authentic DNA fingerprinting analysis. Presents restriction fragment length polymorphism (RFLP) analysis and can serve as a simulated molecular epidemiology laboratory or as a simulated forensic laboratory exercise. (DDR)

  3. Does individualism help explain differences in employers' stigmatizing attitudes toward disability across Chinese and American cities?

    PubMed

    Rao, Deepa; Horton, Randall A; Tsang, Hector W H; Shi, Kan; Corrigan, Patrick W

    2010-11-01

    Stigmatizing attitudes toward people with disabilities can jeopardize such individuals' well-being and recovery through denial of employment and community isolation. By shaping social norms that define group membership, the construct of individualism may partially explain differences in stigmatizing attitudes across cultures. Further, widespread globalization has brought intensely individualistic social practices to certain segments of non-Western cultures. This paper examines whether the construct of individualism can help to explain cross-cultural differences in stigmatizing attitudes observed between American and Chinese employers. Employers (N = 879) from Beijing, Hong Kong, and Chicago provided information on their attitudes toward hiring people with disabilities, and path analyses were conducted to examine potential mediating relationships. Path analyses indicated that vertical individualism, along with perceived responsibility for acquiring a condition, partially mediated the relationship between culture and employers' negative attitudes about job candidates with disabilities. These results suggested that greater espousal of competitive and individualist values may drive stigmatizing attitudes across cultures. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

  4. Does Individualism Help Explain Differences in Employers' Stigmatizing Attitudes Toward Disability Across Chinese and American Cities?

    PubMed Central

    Rao, Deepa; Horton, Randall A.; Tsang, Hector W.H.; Shi, Kan; Corrigan, Patrick W.

    2011-01-01

    Purpose Stigmatizing attitudes toward people with disabilities can jeopardize such individuals' well-being and recovery through denial of employment and community isolation. By shaping social norms that define group membership, the construct of individualism may partially explain differences in stigmatizing attitudes across cultures. Further, widespread globalization has brought intensely individualistic social practices to certain segments of non-Western cultures. This paper examines whether the construct of individualism can help to explain cross-cultural differences in stigmatizing attitudes observed between American and Chinese employers. Design Employers (N = 879) from Beijing, Hong Kong, and Chicago provided information on their attitudes toward hiring people with disabilities, and Path Analyses were conducted to examine potential mediating relationships. Results Path analyses indicated that vertical individualism, along with perceived responsibility for acquiring a condition, partially mediated the relationship between culture and employers' negative attitudes about job candidates with disabilities. Conclusion These results suggested that greater espousal of competitive and individualist values may drive stigmatizing attitudes across cultures. PMID:21171794

  5. Population Well-Being Measures Help Explain Geographic Disparities In Life Expectancy At The County Level

    PubMed Central

    Arora, Anita; Spatz, Erica; Herrin, Jeph; Riley, Carley; Roy, Brita; Kell, Kenneth; Coberley, Carter; Rula, Elizabeth; Krumholz, Harlan M.

    2016-01-01

    Geographic disparities in life expectancy are substantial and not fully explained by differences in race and socioeconomic status. To develop policies that address these inequalities, it is essential to identify other factors that account for this variation. In this study we investigated whether population well-being—a comprehensive measure of physical, mental, and social health—helps explain geographic variation in life expectancy. At the county level, we found that for every 1-standarddeviation (4.2-point) increase in the well-being score, life expectancy was 1.9 years higher for females and 2.6 years higher for males. Life expectancy and well-being remained positively associated, even after race, poverty, and education were controlled for. In addition, well-being partially mediated the established associations of race, poverty, and education with life expectancy. These findings highlight well-being as an important metric of a population’s health and longevity and as a promising focus for intervention. PMID:27834249

  6. Educational Attainment: Success to the Successful

    ERIC Educational Resources Information Center

    Anthony, Peter; Gould, David; Smith, Gina

    2013-01-01

    Systems archetypes are patterns of structure found in systems that are helpful in understanding some of the dynamics within them. The intent of this study was to examine educational attainment data using the success-to-the-successful archetype as a model to see if it helps to explain the inequality observed in the data. Data covering 1990 to 2009…

  7. Afraid To Be Heard: The Selectively Mute Child.

    ERIC Educational Resources Information Center

    Longo, Sharon L.

    2001-01-01

    Presents facts about selective mutism, an anxiety disorder believed to be caused by low levels of serotonin in the brain, discussing its effects on school children, explaining how to get the necessary help (e.g., talking to health professionals and becoming educated about the disorder), and noting what parents can do (e.g., help raise the child's…

  8. Who Is Likely to Help and Hurt? Profiles of African American Adolescents with Prosocial and Aggressive Behavior

    ERIC Educational Resources Information Center

    Belgrave, Faye Z.; Nguyen, Anh B.; Johnson, Jessica L.; Hood, Kristina

    2011-01-01

    Prosocial behavior and aggression among children and adolescents are important indicators of social and interpersonal competence. The goal of this study was to investigate whether there are different prototypes among African American adolescents that can help explain prosocial and aggressive (relational and overt) behaviors. Also of interest was…

  9. Generics Pricing: The Greek Paradox.

    PubMed

    Karafyllis, Ioannis; Variti, Lamprini

    2017-01-01

    This paper explains and develops a methodological framework to help evaluate the performance of generic pharmaceutical policies and the correct evaluation of generics sales. Until today erroneous recording of generics does not help proper pricing and their penetration in the Greek market. This classifies Greece on the outliners in every study or comparison that is referred on papers or studies.

  10. [Parenting Information: Teenagers. Informacion Para los Padres: Sobre los Jovenes.

    ERIC Educational Resources Information Center

    Moreno, Steve

    These four booklets are devoted specifically to the concerns of parents and their teenage children and are part of a series of 22 booklets designed specifically to help parents understand their children and help them to learn. "Parents--Learn about Your Teenager" (booklet #6) explains the changes which occur during the teen years and the…

  11. Biomass and health based forest cover delineation using spectral un-mixing

    Treesearch

    Mohan Tiruveedhula; Joseph Fan; Ravi R. Sadasivuni; Surya S. Durbha; David L. Evans

    2009-01-01

    Remote sensing is a well-suited source of information on various forest characteristics such as forest cover type, leaf area, biomass, and health. The use of appropriate layers helps to quantify the variables of interest. For example, normalized difference vegetation index (NDVI) and greenness help explain variability in biomass as well as health of forests....

  12. Analyzing Forces on Amusement Park Rides with Mobile Devices

    ERIC Educational Resources Information Center

    Vieyra, Rebecca E.; Vieyra, Chrystian

    2014-01-01

    Mobile device accelerometers are a simple and easy way for students to collect accurate and detailed data on an amusement park ride. The resulting data can be graphed to assist in the creation of force diagrams to help students explain their physical sensations while on the ride. This type of activity can help students overcome some of the…

  13. Teaching English for and with Communities

    ERIC Educational Resources Information Center

    Salas, Spencer; Safaradan, Majid; de le Torre Ugarte, Ana Maria

    2008-01-01

    This article is a reflection of English teaching in Chiclayo, Peru, at a not-for-profit cultural center. It starts with a brief explanation of the authors' desire to help transform the community through English teaching. The article then explains the concept of civic education and offers a three-tiered approach that has been designed to help the…

  14. Evolution. Animal Life in Action[TM]. Schlessinger Science Library. [Videotape].

    ERIC Educational Resources Information Center

    2000

    This 23-minute videotape for grades 5-8, presents the myriad of animal life that exists on the planet. Students can view and perform experiments and investigations that help explain animal traits and habits. The story of evolution starts with the study of fossils that helps scientists link today's living organisms with those of the past. Students…

  15. Individual Differences in Toddlers' Prosociality: Experiences in Early Relationships Explain Variability in Prosocial Behavior

    ERIC Educational Resources Information Center

    Newton, Emily K.; Thompson, Ross A.; Goodman, Miranda

    2016-01-01

    Latent class logistic regression analysis was used to investigate sources of individual differences in profiles of prosocial behavior. Eighty-seven 18-month-olds were observed in tasks assessing sharing with a neutral adult, instrumentally helping a neutral adult, and instrumentally helping a sad adult. Maternal mental state language (MSL) and…

  16. Teachers' Behavior and Pupils' Achievement Motivation as Determinants of Intended Helping Behavior in Physical Education

    ERIC Educational Resources Information Center

    Kokkonen, Juha A.; Kokkonen, Marja T.; Telama, Risto K.; Liukkonen, Jarmo O.

    2013-01-01

    The present two-wave longitudinal study examined the extent to which physical education (PE) teachers' democratic and socially supportive behavior, pupils' goal orientations, and the perceived motivational climate in PE explained differences in pupils' intended helping behavior by gender in PE classes. The results of 105 boys and 109 girls based…

  17. Development of a novel humanoid-robot simulator for endoscope with pharyngeal reflex and real-life responses.

    PubMed

    Ueki, Masaru; Uehara, Kazutake; Isomoto, Hajime

    2018-05-15

    In recent years, there has been a growing need for skills quantification of endoscopic specialist. Various educational simulators have been created to help increase the endoscopy performance of medical students and trainees. Recent research seems to show that the use of simulators helps increase the skill level of endoscopists, while improving patient safety 1, 2 . However, previous simulators lack sufficient realism and are unable to replicate natural human reactions during endoscopy or quantify endoscopic skills. We developed a novel humanoid-robot simulator (named mikoto ® ) with pharyngeal reflexes and real-life responses to endoscopy. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  18. Uncertainty of future projections of species distributions in mountainous regions.

    PubMed

    Tang, Ying; Winkler, Julie A; Viña, Andrés; Liu, Jianguo; Zhang, Yuanbin; Zhang, Xiaofeng; Li, Xiaohong; Wang, Fang; Zhang, Jindong; Zhao, Zhiqiang

    2018-01-01

    Multiple factors introduce uncertainty into projections of species distributions under climate change. The uncertainty introduced by the choice of baseline climate information used to calibrate a species distribution model and to downscale global climate model (GCM) simulations to a finer spatial resolution is a particular concern for mountainous regions, as the spatial resolution of climate observing networks is often insufficient to detect the steep climatic gradients in these areas. Using the maximum entropy (MaxEnt) modeling framework together with occurrence data on 21 understory bamboo species distributed across the mountainous geographic range of the Giant Panda, we examined the differences in projected species distributions obtained from two contrasting sources of baseline climate information, one derived from spatial interpolation of coarse-scale station observations and the other derived from fine-spatial resolution satellite measurements. For each bamboo species, the MaxEnt model was calibrated separately for the two datasets and applied to 17 GCM simulations downscaled using the delta method. Greater differences in the projected spatial distributions of the bamboo species were observed for the models calibrated using the different baseline datasets than between the different downscaled GCM simulations for the same calibration. In terms of the projected future climatically-suitable area by species, quantification using a multi-factor analysis of variance suggested that the sum of the variance explained by the baseline climate dataset used for model calibration and the interaction between the baseline climate data and the GCM simulation via downscaling accounted for, on average, 40% of the total variation among the future projections. Our analyses illustrate that the combined use of gridded datasets developed from station observations and satellite measurements can help estimate the uncertainty introduced by the choice of baseline climate information to the projected changes in species distribution.

  19. Uncertainty of future projections of species distributions in mountainous regions

    PubMed Central

    Tang, Ying; Viña, Andrés; Liu, Jianguo; Zhang, Yuanbin; Zhang, Xiaofeng; Li, Xiaohong; Wang, Fang; Zhang, Jindong; Zhao, Zhiqiang

    2018-01-01

    Multiple factors introduce uncertainty into projections of species distributions under climate change. The uncertainty introduced by the choice of baseline climate information used to calibrate a species distribution model and to downscale global climate model (GCM) simulations to a finer spatial resolution is a particular concern for mountainous regions, as the spatial resolution of climate observing networks is often insufficient to detect the steep climatic gradients in these areas. Using the maximum entropy (MaxEnt) modeling framework together with occurrence data on 21 understory bamboo species distributed across the mountainous geographic range of the Giant Panda, we examined the differences in projected species distributions obtained from two contrasting sources of baseline climate information, one derived from spatial interpolation of coarse-scale station observations and the other derived from fine-spatial resolution satellite measurements. For each bamboo species, the MaxEnt model was calibrated separately for the two datasets and applied to 17 GCM simulations downscaled using the delta method. Greater differences in the projected spatial distributions of the bamboo species were observed for the models calibrated using the different baseline datasets than between the different downscaled GCM simulations for the same calibration. In terms of the projected future climatically-suitable area by species, quantification using a multi-factor analysis of variance suggested that the sum of the variance explained by the baseline climate dataset used for model calibration and the interaction between the baseline climate data and the GCM simulation via downscaling accounted for, on average, 40% of the total variation among the future projections. Our analyses illustrate that the combined use of gridded datasets developed from station observations and satellite measurements can help estimate the uncertainty introduced by the choice of baseline climate information to the projected changes in species distribution. PMID:29320501

  20. Conformational Transition Pathway in the Activation Process of Allosteric Glucokinase

    PubMed Central

    Shi, Ting; Zhao, Yaxue; Chen, Yingyi; Li, Xiaobai; Liu, Xinyi; Huang, Zhimin; Zhang, Jian

    2013-01-01

    Glucokinase (GK) is a glycolytic enzyme that plays an important role in regulating blood glucose level, thus acting as a potentially attractive target for drug discovery in the treatment of diabetes of the young type 2 and persistent hyperinsulinemic hypoglycemia of infancy. To characterize the activation mechanism of GK from the super-open state (inactive state) to the closed state (active state), a series of conventional molecular dynamics (MD) and targeted MD (TMD) simulations were performed on this enzyme. Conventional MD simulation showed a specific conformational ensemble of GK when the enzyme is inactive. Seven TMD simulations depicted a reliably conformational transition pathway of GK from the inactive state to the active state, and the components important to the conformational change of GK were identified by analyzing the detailed structures of the TMD trajectories. In combination with the inactivation process, our findings showed that the whole conformational pathway for the activation-inactivation-activation of GK is a one-direction circulation, and the active state is less stable than the inactive state in the circulation. Additionally, glucose was demonstrated to gradually modulate its binding pose with the help of residues in the large domain and connecting region of GK during the activation process. Furthermore, the obtained energy barriers were used to explain the preexisting equilibrium and the slow binding kinetic process of the substrate by GK. The simulated results are in accordance with the recent findings from the mutagenesis experiments and kinetic analyses. Our observations reveal a complicated conformational process in the allosteric protein, resulting in new knowledge about the delicate mechanisms for allosteric biological macromolecules that will be useful in drug design for targeting allosteric proteins. PMID:23409066

  1. Solid H2 in the interstellar medium

    NASA Astrophysics Data System (ADS)

    Füglistaler, A.; Pfenniger, D.

    2018-06-01

    Context. Condensation of H2 in the interstellar medium (ISM) has long been seen as a possibility, either by deposition on dust grains or thanks to a phase transition combined with self-gravity. H2 condensation might explain the observed low efficiency of star formation and might help to hide baryons in spiral galaxies. Aims: Our aim is to quantify the solid fraction of H2 in the ISM due to a phase transition including self-gravity for different densities and temperatures in order to use the results in more complex simulations of the ISM as subgrid physics. Methods: We used molecular dynamics simulations of fluids at different temperatures and densities to study the formation of solids. Once the simulations reached a steady state, we calculated the solid mass fraction, energy increase, and timescales. By determining the power laws measured over several orders of magnitude, we extrapolated to lower densities the higher density fluids that can be simulated with current computers. Results: The solid fraction and energy increase of fluids in a phase transition are above 0.1 and do not follow a power law. Fluids out of a phase transition are still forming a small amount of solids due to chance encounters of molecules. The solid mass fraction and energy increase of these fluids are linearly dependent on density and can easily be extrapolated. The timescale is below one second, the condensation can be considered instantaneous. Conclusions: The presence of solid H2 grains has important dynamic implications on the ISM as they may be the building blocks for larger solid bodies when gravity is included. We provide the solid mass fraction, energy increase, and timescales for high density fluids and extrapolation laws for lower densities.

  2. Training Social Workers, Clients, and Students in the Use of Rural Natural Helping Networks.

    ERIC Educational Resources Information Center

    Morris, Judson H.; Hilbert, Judith Cicero

    A manual, geared toward training social workers going into rural areas, provides a brief discussion of the natural helping relationships found in rural communities and a simulation game to be used in acquainting social workers, clients, and students with the rural network. Objectives of the simulation game, Nets and Links, are to train people to…

  3. Developing iPad-Based Physics Simulations That Can Help People Learn Newtonian Physics Concepts

    ERIC Educational Resources Information Center

    Lee, Young-Jin

    2015-01-01

    The aims of this study are: (1) to develop iPad-based computer simulations called iSimPhysics that can help people learn Newtonian physics concepts; and (2) to assess its educational benefits and pedagogical usefulness. To facilitate learning, iSimPhysics visualizes abstract physics concepts, and allows for conducting a series of computer…

  4. Fast-ion stabilization of tokamak plasma turbulence

    NASA Astrophysics Data System (ADS)

    Di Siena, A.; Görler, T.; Doerk, H.; Poli, E.; Bilato, R.

    2018-05-01

    A significant reduction of the turbulence-induced anomalous heat transport has been observed in recent studies of magnetically confined plasmas in the presence of a significant fast-ion fractions. Therefore, the control of fast-ion populations with external heating might open the way to more optimistic scenarios for future fusion devices. However, little is known about the parameter range of relevance of these fast-ion effects which are often only highlighted in correlation with substantial electromagnetic fluctuations. Here, a significant fast ion induced stabilization is also found in both linear and nonlinear electrostatic gyrokinetic simulations which cannot be explained with the conventional assumptions based on pressure profile and dilution effects. Strong wave-fast particle resonant interactions are observed for realistic parameters where the fast particle trace approximation clearly failed and explained with the help of a reduced Vlasov model. In contrast to previous interpretations, fast particles can actively modify the Poisson field equation—even at low fast particle densities where dilution tends to be negligible and at relatively high temperatures, i.e. T  <  30T e . Further key parameters controlling the role of the fast ions are identified in the following and various ways of further optimizing their beneficial impact are explored. Finally, possible extensions into the electromagnetic regime are briefly discussed and the relevance of these findings for ITER standard scenarios is highlighted.

  5. Alpha-Helical Protein Networks Are Self-Protective and Flaw-Tolerant

    PubMed Central

    Ackbarow, Theodor; Sen, Dipanjan; Thaulow, Christian; Buehler, Markus J.

    2009-01-01

    Alpha-helix based protein networks as they appear in intermediate filaments in the cell’s cytoskeleton and the nuclear membrane robustly withstand large deformation of up to several hundred percent strain, despite the presence of structural imperfections or flaws. This performance is not achieved by most synthetic materials, which typically fail at much smaller deformation and show a great sensitivity to the existence of structural flaws. Here we report a series of molecular dynamics simulations with a simple coarse-grained multi-scale model of alpha-helical protein domains, explaining the structural and mechanistic basis for this observed behavior. We find that the characteristic properties of alpha-helix based protein networks are due to the particular nanomechanical properties of their protein constituents, enabling the formation of large dissipative yield regions around structural flaws, effectively protecting the protein network against catastrophic failure. We show that the key for these self protecting properties is a geometric transformation of the crack shape that significantly reduces the stress concentration at corners. Specifically, our analysis demonstrates that the failure strain of alpha-helix based protein networks is insensitive to the presence of structural flaws in the protein network, only marginally affecting their overall strength. Our findings may help to explain the ability of cells to undergo large deformation without catastrophic failure while providing significant mechanical resistance. PMID:19547709

  6. Slowing down of North Pacific climate variability and its implications for abrupt ecosystem change.

    PubMed

    Boulton, Chris A; Lenton, Timothy M

    2015-09-15

    Marine ecosystems are sensitive to stochastic environmental variability, with higher-amplitude, lower-frequency--i.e., "redder"--variability posing a greater threat of triggering large ecosystem changes. Here we show that fluctuations in the Pacific Decadal Oscillation (PDO) index have slowed down markedly over the observational record (1900-present), as indicated by a robust increase in autocorrelation. This "reddening" of the spectrum of climate variability is also found in regionally averaged North Pacific sea surface temperatures (SSTs), and can be at least partly explained by observed deepening of the ocean mixed layer. The progressive reddening of North Pacific climate variability has important implications for marine ecosystems. Ecosystem variables that respond linearly to climate forcing will have become prone to much larger variations over the observational record, whereas ecosystem variables that respond nonlinearly to climate forcing will have become prone to more frequent "regime shifts." Thus, slowing down of North Pacific climate variability can help explain the large magnitude and potentially the quick succession of well-known abrupt changes in North Pacific ecosystems in 1977 and 1989. When looking ahead, despite model limitations in simulating mixed layer depth (MLD) in the North Pacific, global warming is robustly expected to decrease MLD. This could potentially reverse the observed trend of slowing down of North Pacific climate variability and its effects on marine ecosystems.

  7. Age-specific bone tumour incidence rates are governed by stem cell exhaustion influencing the supply and demand of progenitor cells.

    PubMed

    Richardson, Richard B

    2014-07-01

    Knudson's carcinogenic model, which simulates incidence rates for retinoblastoma, provides compelling evidence for a two-stage mutational process. However, for more complex cancers, existing multistage models are less convincing. To fill this gap, I hypothesize that neoplasms preferentially arise when stem cell exhaustion creates a short supply of progenitor cells at ages of high proliferative demand. To test this hypothesis, published datasets were employed to model the age distribution of osteochondroma, a benign lesion, and osteosarcoma, a malignant one. The supply of chondrogenic stem-like cells in femur growth plates of children and adolescents was evaluated and compared with the progenitor cell demand of longitudinal bone growth. Similarly, the supply of osteoprogenitor cells from birth to old age was compared with the demands of bone formation. Results show that progenitor cell demand-to-supply ratios are a good risk indicator, exhibiting similar trends to the unimodal and bimodal age distributions of osteochondroma and osteosarcoma, respectively. The hypothesis also helps explain Peto's paradox and the finding that taller individuals are more prone to cancers and have shorter lifespans. The hypothesis was tested, in the manner of Knudson, by its ability to convincingly explain and demonstrate, for the first time, a bone tumour's bimodal age-incidence curve. Crown Copyright © 2014. Published by Elsevier Ireland Ltd. All rights reserved.

  8. Investigation of relationships between fMRI brain networks in the spectral domain using ICA and Granger causality reveals distinct differences between schizophrenia patients and healthy controls

    PubMed Central

    Demirci, Oguz; Stevens, Michael C.; Andreasen, Nancy C.; Michael, Andrew; Liu, Jingyu; White, Tonya; Pearlson, Godfrey D.; Clark, Vincent P.; Calhoun, Vince D.

    2009-01-01

    Functional network connectivity (FNC) is an approach that examines the relationships between brain networks (as opposed to functional connectivity (FC) that focuses upon the relationships between single voxels). FNC may help explain the complex relationships between distributed cerebral sites in the brain and possibly provide new understanding of neurological and psychiatric disorders such as schizophrenia. In this paper, we use independent component analysis (ICA) to extract the time courses of spatially independent components and then use these in Granger causality test (GCT) to investigate causal relationships between brain activation networks. We present results using both simulations and fMRI data of 155 subjects obtained during two different tasks. Unlike previous research, causal relationships are presented over different portions of the frequency spectrum in order to differentiate high and low frequency effects and not merged in a scalar. The results obtained using Sternberg item recognition paradigm (SIRP) and auditory oddball (AOD) tasks showed FNC differentiations between schizophrenia and control groups, and explained how the two groups differed during these tasks. During the SIRP task, secondary visual and cerebellum activation networks served as hubs and included most complex relationships between the activated regions. Secondary visual and temporal lobe activations replaced these components during the AOD task. PMID:19245841

  9. A Group Simulation of the Development of the Geologic Time Scale.

    ERIC Educational Resources Information Center

    Bennington, J. Bret

    2000-01-01

    Explains how to demonstrate to students that the relative dating of rock layers is redundant. Uses two column diagrams to simulate stratigraphic sequences from two different geological time scales and asks students to complete the time scale. (YDS)

  10. Possible role of the W-Z-top-quark bags in baryogenesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Flambaum, Victor V.; Shuryak, Edward; Department of Physics, State University of New York, Stony Brook, New York 11794

    2010-10-01

    The heaviest members of the standard model--the gauge bosons W, Z and the top quarks and antiquarks--may form collective baglike excitations of the Higgs vacuum provided their number is large enough, at both zero and finite temperatures. Since the Higgs vacuum expectation value is significantly modified inside them, they are called 'bags'. In this work we argue that creation of such objects can explain certain numerical studies of cosmological baryogenesis. Using as an example a hybrid model combining inflationary preheating with cold electroweak transition, we identify 'spots of unbroken phase' found in numerical studies of this scenario with such W-Zmore » bags. We argue that the baryon number violation should happen predominantly inside these objects, and we show that the rates calculated in numerical simulations can be analytically explained using finite-size, pure gauge sphaleron solutions, developed previously in the QCD context by Carter, Ostrovsky, and Shuryak. Furthermore, we point out significant presence of the top quarks/antiquarks in these bags (which were not included in those numerical studies). Although the basic sphaleron exponent remains unchanged by the tops' presence, we find that tops help to stabilize them for a longer time. Another enhancement of the transition rate comes from the 'recycling'' of the tops in the topological transition. Inclusion of the fermions (tops) enhances the sphaleron rate by up to 2 orders of magnitude. Finally, we discuss the magnitude of the CP violation needed to explain the observed baryonic asymmetry of the Universe and give arguments that the difference in the top-antitop population in the bag of the right magnitude can arise both from CP asymmetries in the top decays and in top propagation into the bags, due to the Farrar-Shaposhnikov effect.« less

  11. A dynamic processes study of PM retention by trees under different wind conditions.

    PubMed

    Xie, Changkun; Kan, Liyan; Guo, Jiankang; Jin, Sijia; Li, Zhigang; Chen, Dan; Li, Xin; Che, Shengquan

    2018-02-01

    Particulate matter (PM) is one of the most serious environmental problems, exacerbating respiratory and vascular illnesses. Plants have the ability to reduce non-point source PM pollution through retention on leaves and branches. Studies of the dynamic processes of PM retention by plants and the mechanisms influencing this process will help to improve the efficiency of urban greening for PM reduction. We examined dynamic processes of PM retention and the major factors influencing PM retention by six trees with different branch structure characteristics in wind tunnel experiments at three different wind speeds. The results showed that the changes of PM numbers retained by plant leaves over time were complex dynamic processes for which maximum values could exceed minimum values by over 10 times. The average value of PM measured in multiple periods and situations can be considered a reliable indicator of the ability of the plant to retain PM. The dynamic processes were similar for PM 10 and PM 2.5 . They could be clustered into three groups simulated by continually-rising, inverse U-shaped, and U-shaped polynomial functions, respectively. The processes were the synthetic effect of characteristics such as species, wind speed, period of exposure and their interactions. Continually-rising functions always explained PM retention in species with extremely complex branch structure. Inverse U-shaped processes explained PM retention in species with relatively simple branch structure and gentle wind. The U-shaped processes mainly explained PM retention at high wind speeds and in species with a relatively simple crown. These results indicate that using plants with complex crowns in urban greening and decreasing wind speed in plant communities increases the chance of continually-rising or inverse U-shaped relationships, which have a positive effect in reducing PM pollution. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Extract useful knowledge from agro-hydrological simulations data for decision making

    NASA Astrophysics Data System (ADS)

    Gascuel-odoux, C.; Bouadi, T.; Cordier, M.; Quiniou, R.

    2013-12-01

    In recent years, models have been developed and used to test the effect of scenarios and help stakeholders in decision making. Agro-hydrological models have guided agricultural water management by testing the effect of landscape structure and farming system changes on water quantity and quality. Such models generate a large amount of data but few are stored and are often not customized for stakeholders, so that a great amount of information is lost from the simulation process or not transformed in a usable format. A first approach, already published (Trepos et al., 2012), has been developed to identify object oriented tree patterns, that represent surface flow and pollutant pathways from plot to plot, involved in water pollution by herbicides. A simulation model (Gascuel-odoux et al., 2009) predicted herbicide transfer rate, defined as the proportion of applied herbicide that reaches water courses. The predictions were used as a set of learning examples for symbolic learning techniques to induce rules based on qualitative and quantitative attributes and explain two extreme classes in transfer rate. Two automatic symbolic learning techniques were used: the inductive logic programming approach to induce spatial tree patterns, and an attribute-value method to induce aggregated attributes of the trees. A visualization interface allows the users to identify rules explaining contamination and mitigation measures improving the current situation. A second approach has been recently developed to analyse directly the simulated data (Bouadi et al, submitted). A data warehouse called N-catch has been built to store and manage simulation data from the agro-hydrological model TNT2 (Beaujouan et al., 2002). 44 output key simulated variables are stored per plot and at a daily time step on a 50 squared km area, i.e, 8 GB of storage size. After identifying the set of multileveled dimensions integrating hierarchical structures and relationships among related dimension levels, N-Catch has been designed using the open source Business Intelligence Platform Pentaho. We show how to use online analytical processing (OLAP) to access and exploit, intuitively and quickly, the multidimensional and aggregated data from the N-Catch data warehouse. We illustrate how the data warehouse can be used to explore spatio-temporal dimensions efficiently and to discover new knowledge at multiple levels of simulation. OLAP tool can be used to synthesize environmental information and understand nitrogen emissions in water bodies by generating comparative and personalized views of historical data. This DWH is currently extended with data mining or information retrieval methods as Skyline queries to perform advanced analyses (Bouadi et al., 2012). Bouadi et al. N-Catch: A Data Warehouse for Multilevel Analysis of Simulated Nitrogen Data from an Agro-hydrological Model. Submitted. Bouadi et al., 2012) Bouadi, T., Cordier, M., and Quiniou, R. (2012). Incremental computation of skyline queries with dynamic preferences. In DEXA (1), pages 219-233. Trepos et al. 2012. Mining simulation data by rule induction to determine critical source areas of stream water pollution by herbicides. Computers and Electronics in Agriculture 86, 75-88.

  13. Divining Testimony? The Impact of Interviewing Props on Children’s Reports of Touching

    PubMed Central

    Poole, Debra Ann; Bruck, Maggie

    2012-01-01

    There is a long-held assumption that objects help bridge the gap between what children know and what they can (or are willing to) explain. In this review, we present research on the extent to which two types of objects used as props in investigative interviews of children, anatomical dolls and body (human figure) diagrams, actually help children report accurate information about autobiographical events. We explain why available research does not instill confidence that props are the best solution to interviewing challenges, and we consider practitioners’ and policy-makers responses to this evidence. Finally, we discuss the types of developmental research that are necessary to advance the field of evidence-based interviewing of children. PMID:23144526

  14. Therapeutic Assessment of a Violent Criminal Offender: Managing the Cultural Narrative of Evil.

    PubMed

    Chudzik, Lionel

    2016-01-01

    Therapeutic Assessment (TA) emphasizes the importance of the clinical relationship and the core values of collaboration, respect, humility, compassion, and curiosity, which guide all aspects of the endeavor (Finn, 2007 ). Those values are not easy to apply with violent offenders. However, this article explains how TA can significantly contribute to the treatment of those clients by helping the therapist avoid common cultural narratives about evil. We see that these culturally based myths permit us to explain violent behaviors, but also prevent us from treating them because they lead us to a circular countertransference-transference process. Through a clinical case, I show how the TA process can help us to work empathically with violent people while addressing the dangerousness effectively.

  15. Explain the Behavior Intention to Use e-Learning Technologies: A Unified Theory of Acceptance and Use of Technology Perspective

    ERIC Educational Resources Information Center

    Shaqrah, Amin A.

    2015-01-01

    The purpose of this study is to explain the behavior intention to use e-learning technologies. In order to achieve a better view and validate the study, researcher attempts to give details of how technology acceptance models help Jordanian trainees firms in accepting e-learning technology, and how if applied will result more attention to usage…

  16. A Model of Situational Willingness to Communicate (WTC) in the Study Abroad Context

    ERIC Educational Resources Information Center

    Robson, Graham

    2015-01-01

    The use of structural modeling has helped to explain constructs leading to Willingness to Communicate (WTC) in L1 and L2 contexts. When WTC was conceptualized as a trait in the L1, more personality variables were used in models. When WTC moved into the realm of second language, researchers still used trait measurements to explain the construct,…

  17. Seedling growth responses to light and mineral N form are predicted by species ecologies and can help explain tree diversity

    Treesearch

    Michael B. Walters; John L. Willis; Kurt W. Gottschalk

    2014-01-01

    Tree species distributions and diversity could be explained by rank changes in performance over multiple spatiotemporal resource gradients, i.e., resource partitioning. For 14 species planted in 45 harvest gap and closed canopy locations in a mesic northern hardwood forest community, Michigan, USA, we asked the following questions: (i) are species growth responses to...

  18. Aviation Safety Simulation Model

    NASA Technical Reports Server (NTRS)

    Houser, Scott; Yackovetsky, Robert (Technical Monitor)

    2001-01-01

    The Aviation Safety Simulation Model is a software tool that enables users to configure a terrain, a flight path, and an aircraft and simulate the aircraft's flight along the path. The simulation monitors the aircraft's proximity to terrain obstructions, and reports when the aircraft violates accepted minimum distances from an obstruction. This model design facilitates future enhancements to address other flight safety issues, particularly air and runway traffic scenarios. This report shows the user how to build a simulation scenario and run it. It also explains the model's output.

  19. Adaptive and Rational Anticipations in Risk Management Systems and Economy

    NASA Astrophysics Data System (ADS)

    Dubois, Daniel M.; Holmberg, Stig C.

    2010-11-01

    The global financial crisis of year 2009 is explained as a result of uncoordinated risk management decisions in business firms and economic organisations. The underlying reason for this can be found in the current financial system. As the financial market has lost much of its direct coupling to the concrete economy it provides misleading information to economic decision makers at all levels. Hence, the financial system has moved from a state of moderate and slow cyclical fluctuations into a state of fast and chaotic ones. Those misleading decisions can further be described, but not explained, by help of adaptive and rational expectations from macroeconomic theory. In this context, AE, the Adaptive Expectations are related to weak passive Exo-anticipation, and RE, the Rational expectations can be related to a strong, active and design oriented anticipation. The shortcomings of conventional cures, which builds on a reactive paradigm, have already been demonstrated in economic literature and are here further underlined by help of Ashby's "Law of Requisite Variety", Weaver's distinction between systems of "Disorganized Complexity" and those of "Organized Complexity", and Klir's "Reconstructability Analysis". Anticipatory decision-making is hence here proposed as a replacement to current expectation based and passive risk management. An anticipatory model of the business cycle is presented for supporting that proposition. The model, which is an extension of the Kaldor-Kalecki model, includes both retardation and anticipation. While cybernetics with the feedback process in control system deals with an explicit goal or purpose given to a system, the anticipatory system discussed here deals with a behaviour for which the future state of the system is built by the system itself, without explicit goal. A system with weak anticipation is based on a predictive model of the system, while a system with strong anticipation builds its own future by itself. Numerical simulations on computer confirm the feasibility of this approach. Hence, functional differential equations with both retardation and anticipation are found to be useful tools for modelling financial systems.

  20. What controls the very quick runoff response in the Meuse basin?

    NASA Astrophysics Data System (ADS)

    Bouaziz, Laurène; Hrachowitz, Markus; Schellekens, Jaap; Weerts, Albrecht; Savenije, Hubert

    2017-04-01

    Currently, the hydrological model used in the operational forecasting system of the river Meuse is lumped and does not account for the heterogeneity of the landscape, topography and vegetation. Previous studies have shown the importance of model structure distribution in different hydrological response units (HRUs) to improve model simulations. These HRUs take into account the different dominant runoff generation processes that occur in different parts of the landscape. The conceptualization of a runoff response with a very rapid time scale is essential to model the rapid runoff generated by very high intensity rainfall events. The parameterization of this rapid runoff response in the different sub-catchments of the Meuse is very sensitive due to the non-linearity of this threshold process and to the spatio-temporal variability of high-intensity rain events. In this study, we formulate several hypotheses on what controls the very quick runoff response in the Meuse basin and we try to use additional sources of data to test the a-priori assumptions that we made in the conceptualization of the HRUs in our hydrological model and to facilitate model parameterization. We hypothesize that by using appropriate runoff signatures, we may be able to assess the importance of the threshold response in the different catchments. The selection of specific storm events is useful to split the runoff in different time scales to improve the a-priori estimation of the very rapid runoff parameterization. Linking these differences to topographic and physiographic properties of the catchment like soil texture and land use may help us to explain the difference in observed spatial patterns. Especially the assessment of the fraction of roads and paved areas that cross the different hydrological response units may help to explain the observed spatial patterns. Additionally, we believe that deriving permanent and temporary wet areas using the Modified Normalized Difference Water Index (MNDWI) may guide us in strengthening or adapting the assumptions we made concerning the HRU classes.

  1. Public opinion: Country comparisons

    NASA Astrophysics Data System (ADS)

    Hopkins, Debbie

    2015-11-01

    Climate change awareness, risk perception and policy support vary between and within countries. National-scale comparisons can help to explain this variability and be used to develop targeted interventions.

  2. Plugging Leaks.

    ERIC Educational Resources Information Center

    Fitzemeyer, Ted

    2000-01-01

    Explains how routine maintenance can help schools and universities avoid plumbing disasters. Common trouble spots and preventive techniques are discussed, as are tips for making repairs without disrupting school activities. (GR)

  3. Simbios: an NIH national center for physics-based simulation of biological structures.

    PubMed

    Delp, Scott L; Ku, Joy P; Pande, Vijay S; Sherman, Michael A; Altman, Russ B

    2012-01-01

    Physics-based simulation provides a powerful framework for understanding biological form and function. Simulations can be used by biologists to study macromolecular assemblies and by clinicians to design treatments for diseases. Simulations help biomedical researchers understand the physical constraints on biological systems as they engineer novel drugs, synthetic tissues, medical devices, and surgical interventions. Although individual biomedical investigators make outstanding contributions to physics-based simulation, the field has been fragmented. Applications are typically limited to a single physical scale, and individual investigators usually must create their own software. These conditions created a major barrier to advancing simulation capabilities. In 2004, we established a National Center for Physics-Based Simulation of Biological Structures (Simbios) to help integrate the field and accelerate biomedical research. In 6 years, Simbios has become a vibrant national center, with collaborators in 16 states and eight countries. Simbios focuses on problems at both the molecular scale and the organismal level, with a long-term goal of uniting these in accurate multiscale simulations.

  4. Simbios: an NIH national center for physics-based simulation of biological structures

    PubMed Central

    Delp, Scott L; Ku, Joy P; Pande, Vijay S; Sherman, Michael A

    2011-01-01

    Physics-based simulation provides a powerful framework for understanding biological form and function. Simulations can be used by biologists to study macromolecular assemblies and by clinicians to design treatments for diseases. Simulations help biomedical researchers understand the physical constraints on biological systems as they engineer novel drugs, synthetic tissues, medical devices, and surgical interventions. Although individual biomedical investigators make outstanding contributions to physics-based simulation, the field has been fragmented. Applications are typically limited to a single physical scale, and individual investigators usually must create their own software. These conditions created a major barrier to advancing simulation capabilities. In 2004, we established a National Center for Physics-Based Simulation of Biological Structures (Simbios) to help integrate the field and accelerate biomedical research. In 6 years, Simbios has become a vibrant national center, with collaborators in 16 states and eight countries. Simbios focuses on problems at both the molecular scale and the organismal level, with a long-term goal of uniting these in accurate multiscale simulations. PMID:22081222

  5. Training value of a fixed-based flight simulator with a dynamic seat

    DOT National Transportation Integrated Search

    2007-08-20

    In this paper, we first explain that pilots experience airplane motion via multiple perceptual systems, which makes motion a candidate for simulation via stimulation of only a subset of these systems. Next, we discuss the relative merit of vestibular...

  6. Numerical investigation of the hydrodynamics of carangiform swimming in the transitional and inertial flow regimes.

    PubMed

    Borazjani, Iman; Sotiropoulos, Fotis

    2008-05-01

    We employ numerical simulation to investigate the hydrodynamics of carangiform locomotion as the relative magnitude of viscous and inertial forces, i.e. the Reynolds number (Re), and the tail-beat frequency, i.e. the Strouhal number (St), are systematically varied. The model fish is a three-dimensional (3D) mackerel-like flexible body undulating with prescribed experimental kinematics of carangiform type. Simulations are carried out for three Re spanning the transitional and inertial flow regimes, Re=300 and 4000 (viscous flow), and infinity (inviscid flow). For each Re there is a critical Strouhal number, St*, at which the net mean force becomes zero, making constant-speed self-propulsion possible. St* is a decreasing function of Re and approaches the range of St at which most carangiform swimmers swim in nature (St approximately 0.25) only as Re approaches infinity. The propulsive efficiency at St* is an increasing function of Re while the power required for swimming is decreasing with Re. For all Re, however, the swimming power is shown to be significantly greater than that required to tow the rigid body at the same speed. We also show that the variation of the total drag and its viscous and form components with St depend on the Re. For Re=300, body undulations increase the drag over the rigid body level, while significant drag reduction is observed for Re=4000. This difference is shown to be due to the fact that at sufficiently high Re the drag force variation with St is dominated by its form component variation, which is reduced by undulatory swimming for St>0.2. Finally, our simulations clarify the 3D structure of various wake patterns observed in experiments--single and double row vortices--and suggest that the wake structure depends primarily on the St. Our numerical findings help elucidate the results of previous experiments with live fish, underscore the importance of scale (Re) effects on the hydrodynamic performance of carangiform swimming, and help explain why in nature this mode of swimming is typically preferred by fast swimmers.

  7. Performance factors in associative learning: assessment of the sometimes competing retrieval model.

    PubMed

    Witnauer, James E; Wojick, Brittany M; Polack, Cody W; Miller, Ralph R

    2012-09-01

    Previous simulations revealed that the sometimes competing retrieval model (SOCR; Stout & Miller, Psychological Review, 114, 759-783, 2007), which assumes local error reduction, can explain many cue interaction phenomena that elude traditional associative theories based on total error reduction. Here, we applied SOCR to a new set of Pavlovian phenomena. Simulations used a single set of fixed parameters to simulate each basic effect (e.g., blocking) and, for specific experiments using different procedures, used fitted parameters discovered through hill climbing. In simulation 1, SOCR was successfully applied to basic acquisition, including the overtraining effect, which is context dependent. In simulation 2, we applied SOCR to basic extinction and renewal. SOCR anticipated these effects with both fixed parameters and best-fitting parameters, although the renewal effects were weaker than those observed in some experiments. In simulation 3a, feature-negative training was simulated, including the often observed transition from second-order conditioning to conditioned inhibition. In simulation 3b, SOCR predicted the observation that conditioned inhibition after feature-negative and differential conditioning depends on intertrial interval. In simulation 3c, SOCR successfully predicted failure of conditioned inhibition to extinguish with presentations of the inhibitor alone under most circumstances. In simulation 4, cue competition, including blocking (4a), recovery from relative validity (4b), and unblocking (4c), was simulated. In simulation 5, SOCR correctly predicted that inhibitors gain more behavioral control than do excitors when they are trained in compound. Simulation 6 demonstrated that SOCR explains the slower acquisition observed following CS-weak shock pairings.

  8. Laser-induced asymmetric faceting and growth of a nano-protrusion on a tungsten tip

    NASA Astrophysics Data System (ADS)

    Yanagisawa, Hirofumi; Zadin, Vahur; Kunze, Karsten; Hafner, Christian; Aabloo, Alvo; Kim, Dong Eon; Kling, Matthias F.; Djurabekova, Flyura; Osterwalder, Jürg; Wuensch, Walter

    2016-12-01

    Irradiation of a sharp tungsten tip by a femtosecond laser and exposed to a strong DC electric field led to reproducible surface modifications. By a combination of field emission microscopy and scanning electron microscopy, we observed asymmetric surface faceting with sub-ten nanometer high steps. The presence of faceted features mainly on the laser-exposed side implies that the surface modification was driven by a laser-induced transient temperature rise on a scale of a couple of picoseconds in the tungsten tip apex. Moreover, we identified the formation of a nano-tip a few nanometers high located at one of the corners of a faceted plateau. The results of simulations emulating the experimental conditions are consistent with the experimental observations. The presented technique would be a new method to fabricate a nano-tip especially for generating coherent electron pulses. The features may also help to explain the origin of enhanced field emission, which leads to vacuum arcs, in high electric field devices such as radio-frequency particle accelerators.

  9. A CME-Driven Solar Wind Disturbance Observed at both Low and High Heliographic Latitudes

    NASA Technical Reports Server (NTRS)

    Gosling, J. T.; McComas, D. J.; Phillips, J. L.; Pizzo, V. J.; Goldstein, B. E.; Forsyth, R. J.; Lepping, R. P.

    1995-01-01

    A solar wind disturbance produced by a fast coronal mass ejection, CME, that departed from the Sun on February 20, 1994 was observed in the ecliptic plane at 1 AU by IMP 8 and at high heliographic latitudes at 3.53 AU by Ulysses. In the ecliptic the disturbance included a strong forward shock but no reverse shock, while at high latitudes the disturbance was bounded by a relatively weak forward-reverse shock pair. It is clear that the disturbance in the ecliptic plane was driven primarily by the relative speed between the CME and a slower ambient solar wind ahead, whereas at higher latitudes the disturbance was driven by expansion of the CME. The combined IMP 8 and Ulysses observations thus provide a graphic illustration of how a single fast CME can produce very different types of solar wind disturbances at low and high heliographic latitudes. Simple numerical simulations help explain observed differences at the two spacecraft.

  10. Experimental study and modeling of atomic-scale friction in zigzag and armchair lattice orientations of MoS2

    PubMed Central

    Li, Meng; Shi, Jialin; Liu, Lianqing; Yu, Peng; Xi, Ning; Wang, Yuechao

    2016-01-01

    Abstract Physical properties of two-dimensional materials, such as graphene, black phosphorus, molybdenum disulfide (MoS2) and tungsten disulfide, exhibit significant dependence on their lattice orientations, especially for zigzag and armchair lattice orientations. Understanding of the atomic probe motion on surfaces with different orientations helps in the study of anisotropic materials. Unfortunately, there is no comprehensive model that can describe the probe motion mechanism. In this paper, we report a tribological study of MoS2 in zigzag and armchair orientations. We observed a characteristic power spectrum and friction force values. To explain our results, we developed a modified, two-dimensional, stick-slip Tomlinson model that allows simulation of the probe motion on MoS2 surfaces by combining the motion in the Mo layer and S layer. Our model fits well with the experimental data and provides a theoretical basis for tribological studies of two-dimensional materials. PMID:27877869

  11. Diversity of neighborhoods promotes cooperation in evolutionary social dilemmas

    NASA Astrophysics Data System (ADS)

    Ma, Yongjuan; Lu, Jun; Shi, Lei

    2017-02-01

    Explaining the evolution of cooperative behavior is one of the most important and interesting problems in a myriad of disciplines, such as evolutionary biology, mathematics, statistical physics, social science and economics Up to now, there have been a great number of works aiming to this issue with the help of evolutionary game theory. However, vast majority of existing literatures simply assume that the interaction neighborhood and replacement neighborhood are symmetric, which seems inconsistent with real-world cases. In this paper, we consider the asymmetrical neighborhood: player of type A, whose factor is controlled by a parameter τ, has four interaction neighbors and four replacement neighbors, while player of type B, whose factor is controlled by a parameter 1 - τ, possess eight interaction neighbors and four replacement neighbors. By means of numerous Monte Carlo simulations, we found that middle τ can make the cooperation reach the highest level While for this finding, its robustness can be further validated in more games.

  12. A stellar audit: the computation of encounter rates for 47 Tucanae and omega Centauri

    NASA Astrophysics Data System (ADS)

    Davies, Melvyn B.; Benz, Willy

    1995-10-01

    Using King-Mitchie models, we compute encounter rates between the various stellar species in the globular clusters omega Cen and 47 Tuc. We also compute event rates for encounters between single stars and a population of primordial binaries. Using these rates, and what we have learnt from hydrodynamical simulations of encounters performed earlier, we compute the production rates of objects such as low-mass X-ray binaries (LMXBs), smothered neutron stars and blue stragglers (massive main-sequence stars). If 10 per cent of the stars are contained in primordial binaries, the production rate of interesting objects from encounters involving these binaries is as large as that from encounters between single stars. For example, encounters involving binaries produce a significant number of blue stragglers in both globular cluster models. The number of smothered neutron stars may exceed the number of LMXBs by a factor of 5-20, which may help to explain why millisecond pulsars are observed to outnumber LMXBs in globular clusters.

  13. Human comment dynamics in on-line social systems

    NASA Astrophysics Data System (ADS)

    Wu, Ye; Zhou, Changsong; Chen, Maoying; Xiao, Jinghua; Kurths, Jürgen

    2010-12-01

    Human comment is studied using data from ‘tianya’ which is one of the most popular on-line social systems in China. We found that the time interval between two consecutive comments on the same topic, called inter-event time, follows a power-law distribution. This result shows that there is no characteristic decay time on a topic. It allows for very long periods without comments that separate bursts of intensive comments. Furthermore, the frequency of a different ID commenting on a topic also follows a power-law distribution. It indicates that there are some “hubs” in the topic who lead the direction of the public opinion. Based on the personal comments habit, a model is introduced to explain these phenomena. The numerical simulations of the model fit well with the empirical results. Our findings are helpful for discovering regular patterns of human behavior in on-line society and the evolution of the public opinion on the virtual as well as real society.

  14. Band alignment of rutile and anatase TiO2

    NASA Astrophysics Data System (ADS)

    Scanlon, David O.; Dunnill, Charles W.; Buckeridge, John; Shevlin, Stephen A.; Logsdail, Andrew J.; Woodley, Scott M.; Catlow, C. Richard A.; Powell, Michael. J.; Palgrave, Robert G.; Parkin, Ivan P.; Watson, Graeme W.; Keal, Thomas W.; Sherwood, Paul; Walsh, Aron; Sokol, Alexey A.

    2013-09-01

    The most widely used oxide for photocatalytic applications owing to its low cost and high activity is TiO2. The discovery of the photolysis of water on the surface of TiO2 in 1972 launched four decades of intensive research into the underlying chemical and physical processes involved. Despite much collected evidence, a thoroughly convincing explanation of why mixed-phase samples of anatase and rutile outperform the individual polymorphs has remained elusive. One long-standing controversy is the energetic alignment of the band edges of the rutile and anatase polymorphs of TiO2 (ref. ). We demonstrate, through a combination of state-of-the-art materials simulation techniques and X-ray photoemission experiments, that a type-II, staggered, band alignment of ~ 0.4 eV exists between anatase and rutile with anatase possessing the higher electron affinity, or work function. Our results help to explain the robust separation of photoexcited charge carriers between the two phases and highlight a route to improved photocatalysts.

  15. Risk adjustment policy options for casemix funding: international lessons in financing reform.

    PubMed

    Antioch, Kathryn M; Ellis, Randall P; Gillett, Steve; Borovnicar, Daniel; Marshall, Ric P

    2007-09-01

    This paper explores modified hospital casemix payment formulae that would refine the diagnosis-related group (DRG) system in Victoria, Australia, which already makes adjustments for teaching, severity and demographics. We estimate alternative casemix funding methods using multiple regressions for individual hospital episodes from 2001 to 2003 on 70 high-deficit DRGs, focussing on teaching hospitals where the largest deficits have occurred. Our casemix variables are diagnosis- and procedure-based severity markers, counts of diagnoses and procedures, disease types, complexity, day outliers, emergency admission and "transfers in." The results are presented for four policy options that vary according to whether all of the dollars or only some are reallocated, whether all or some hospitals are used and whether the alternatives augment or replace existing payments. While our approach identifies variables that help explain patient cost variations, hospital-level simulations suggest that the approaches explored would only reduce teaching hospital underpayment by about 10%. The implications of various policy options are discussed.

  16. Giant fluctuations and structural effects in a flocking epithelium

    NASA Astrophysics Data System (ADS)

    Giavazzi, Fabio; Malinverno, Chiara; Corallino, Salvatore; Ginelli, Francesco; Scita, Giorgio; Cerbino, Roberto

    2017-09-01

    Epithelial cells cultured in a monolayer are very motile in isolation but reach a near-jammed state when mitotic division increases their number above a critical threshold. We have recently shown that a monolayer can be reawakened by over-expression of a single protein, RAB5A, a master regulator of endocytosis. This reawakening of motility was explained in terms of a flocking transition that promotes the emergence of a large-scale collective migratory pattern. Here we focus on the impact of this reawakening on the structural properties of the monolayer. We find that the unjammed monolayer is characterised by a fluidisation at the single cell level, and by enhanced non-equilibrium large-scale number fluctuations at a larger length scale. Also, with the help of numerical simulations, we trace back the origin of these fluctuations to the self-propelled active nature of the constituents, and to the existence of a local alignment mechanism, leading to the spontaneous breaking of the orientational symmetry.

  17. Transport of solar electrons in the turbulent interplanetary magnetic field

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ablaßmayer, J.; Tautz, R. C., E-mail: robert.c.tautz@gmail.com; Dresing, N., E-mail: dresing@physik.uni-kiel.de

    2016-01-15

    The turbulent transport of solar energetic electrons in the interplanetary magnetic field is investigated by means of a test-particle Monte-Carlo simulation. The magnetic fields are modeled as a combination of the Parker field and a turbulent component. In combination with the direct calculation of diffusion coefficients via the mean-square displacements, this approach allows one to analyze the effect of the initial ballistic transport phase. In that sense, the model complements the main other approach in which a transport equation is solved. The major advancement is that, by recording the flux of particles arriving at virtual detectors, intensity and anisotropy-time profilesmore » can be obtained. Observational indications for a longitudinal asymmetry can thus be explained by tracing the diffusive spread of the particle distribution. The approach may be of future help for the systematic interpretation of observations for instance by the solar terrestrial relations observatory (STEREO) and advanced composition explorer (ACE) spacecrafts.« less

  18. The Impact of PTSD Symptoms on Women's Safer-Sex Negotiation: Influence of Ethnicity

    PubMed Central

    Horsey, Katie J.; Palmieri, Patrick A.; Hobfoll, Stevan E.

    2010-01-01

    PTSD has been shown to predict later self reported sexual risk behavior, yet behavioral research is lacking in this area. The present study investigated the impact of PTSD severity on negotiation and interpersonal skills effectiveness in simulated high-risk sexual situations among 368 inner-city women. Participants engaged in role-play scenarios involving 1) refusing sex without a condom, 2) abstaining from drinking prior to sex, and 3) refusing sex until both partners were tested for HIV. Interviews were audio taped and rated along dimensions of negotiation effectiveness by blind raters. Hierarchical linear regression analyses were conducted to investigate the impact of PTSD and ethnicity on 4 theoretically derived skill sets 1) assertiveness, 2) using health and preparedness skills 3) social joining skills and 4) higher order negotiation skills. Generally, results indicated that PTSD severity predicted poorer rated negotiation effectiveness among European Americans, but not African Americans. African Americans' expectations that may prepare them for facing more hardship may help explain ethnic differences. PMID:22267974

  19. Fast neutron sensitivity of neutron detectors based on Boron-10 converter layers

    NASA Astrophysics Data System (ADS)

    Mauri, G.; Messi, F.; Kanaki, K.; Hall-Wilton, R.; Karnickis, E.; Khaplanov, A.; Piscitelli, F.

    2018-03-01

    In the last few years many detector technologies for thermal neutron detection have been developed in order to face the shortage of 3He, which is now much less available and more expensive. Moreover the 3He-based detectors can not fulfil the requirements in performance, e.g. the spatial resolution and the counting rate capability needed for the new instruments. The Boron-10-based gaseous detectors have been proposed as a suitable choice. This and other alternative technologies are being developed at ESS. Higher intensities mean higher signals but higher background as well. The signal-to-background ratio is an important feature to study, in particular the γ-ray and the fast neutron contributions. This paper investigates, for the first time, the fast neutrons sensitivity of 10B-based thermal neutron detector. It presents the study of the detector response as a function of energy threshold and the underlying physical mechanisms. The latter are explained with the help of theoretical considerations and simulations.

  20. An explanation of unstable wetting fronts in soils

    NASA Astrophysics Data System (ADS)

    Steenhuis, Tammo; Parlange, Jean-Yves; Kung, Samuel; Stoof, Cathelijne; Baver, Christine

    2016-04-01

    Despite the findings of Raats on unstable wetting front almost a half a century ago, simulating wetting fronts in soils is still an area of active research. One of the critical questions currently is whether Darcy law is valid at the wetting front. In this talk, we pose that in many cases for dry soils, Darcy's law does not apply because the pressure field across the front is not continuous. Consequently, the wetting front pressure is not dependent on the pressure ahead of the front but is determined by the radius of water meniscuses and the dynamic contact angle of the water. If we further assume since the front is discontinuous, that water flows at one pore at the time, then by using the modified Hoffman relationship - relating the dynamic contact angle to the pore water velocity - we find the elevated pressures at the wetting front typical for unstable flows that are similar to those observed experimentally in small diameter columns. The theory helps also explain the funnel flow phenomena observed in layered soils.

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