Sample records for single letter codes
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Is the orthographic/phonological onset a single unit in reading aloud?
Mousikou, Petroula; Coltheart, Max; Saunders, Steven; Yen, Lisa
2010-02-01
Two main theories of visual word recognition have been developed regarding the way orthographic units in printed words map onto phonological units in spoken words. One theory suggests that a string of single letters or letter clusters corresponds to a string of phonemes (Coltheart, 1978; Venezky, 1970), while the other suggests that a string of single letters or letter clusters corresponds to coarser phonological units, for example, onsets and rimes (Treiman & Chafetz, 1987). These theoretical assumptions were critical for the development of coding schemes in prominent computational models of word recognition and reading aloud. In a reading-aloud study, we tested whether the human reading system represents the orthographic/phonological onset of printed words and nonwords as single units or as separate letters/phonemes. Our results, which favored a letter and not an onset-coding scheme, were successfully simulated by the dual-route cascaded (DRC) model (Coltheart, Rastle, Perry, Langdon, & Ziegler, 2001). A separate experiment was carried out to further adjudicate between 2 versions of the DRC model.
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Deep generative learning of location-invariant visual word recognition.
Di Bono, Maria Grazia; Zorzi, Marco
2013-01-01
It is widely believed that orthographic processing implies an approximate, flexible coding of letter position, as shown by relative-position and transposition priming effects in visual word recognition. These findings have inspired alternative proposals about the representation of letter position, ranging from noisy coding across the ordinal positions to relative position coding based on open bigrams. This debate can be cast within the broader problem of learning location-invariant representations of written words, that is, a coding scheme abstracting the identity and position of letters (and combinations of letters) from their eye-centered (i.e., retinal) locations. We asked whether location-invariance would emerge from deep unsupervised learning on letter strings and what type of intermediate coding would emerge in the resulting hierarchical generative model. We trained a deep network with three hidden layers on an artificial dataset of letter strings presented at five possible retinal locations. Though word-level information (i.e., word identity) was never provided to the network during training, linear decoding from the activity of the deepest hidden layer yielded near-perfect accuracy in location-invariant word recognition. Conversely, decoding from lower layers yielded a large number of transposition errors. Analyses of emergent internal representations showed that word selectivity and location invariance increased as a function of layer depth. Word-tuning and location-invariance were found at the level of single neurons, but there was no evidence for bigram coding. Finally, the distributed internal representation of words at the deepest layer showed higher similarity to the representation elicited by the two exterior letters than by other combinations of two contiguous letters, in agreement with the hypothesis that word edges have special status. These results reveal that the efficient coding of written words-which was the model's learning objective-is largely based on letter-level information.
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Computational models of location-invariant orthographic processing
NASA Astrophysics Data System (ADS)
Dandurand, Frédéric; Hannagan, Thomas; Grainger, Jonathan
2013-03-01
We trained three topologies of backpropagation neural networks to discriminate 2000 words (lexical representations) presented at different positions of a horizontal letter array. The first topology (zero-deck) contains no hidden layer, the second (one-deck) has a single hidden layer, and for the last topology (two-deck), the task is divided in two subtasks implemented as two stacked neural networks, with explicit word-centred letters as intermediate representations. All topologies successfully simulated two key benchmark phenomena observed in skilled human reading: transposed-letter priming and relative-position priming. However, the two-deck topology most accurately simulated the ability to discriminate words from nonwords, while containing the fewest connection weights. We analysed the internal representations after training. Zero-deck networks implement a letter-based scheme with a position bias to differentiate anagrams. One-deck networks implement a holographic overlap coding in which representations are essentially letter-based and words are linear combinations of letters. Two-deck networks also implement holographic-coding.
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The Representation of Action Plans in Long Term Memory
NASA Technical Reports Server (NTRS)
Fussfeld, G. N.; Koenig, W.; Karis, D.
1984-01-01
A sequence of experiments conducted on a two hand chord typewriter, to compare the efficiency of different coding principles employed to associate letters with their chord productions is described. This keyboard represents an effort to identify effective alternatives to the existing typewriter. It consists of two seperate 5-key panels (one for each hand), and letters are entered by typing chords composed of one to five fingers. Each panel is capable of producing the full alphabet. One group of experiments was designed to separate between perceptual and motor factors in the acivation of single letter chords. The results underline the importance of perceptual factors in the activation of motor plans. The complexity of the patterns employed to represent letters was shown to account for 50 percent of variance in the typing speeds of single letters. The theoretical implications of these results are discussed in relation to a vision based theory of action plans.
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ERIC Educational Resources Information Center
Davis, Colin J.; Bowers, Jeffrey S.
2006-01-01
Five theories of how letter position is coded are contrasted: position-specific slot-coding, Wickelcoding, open-bigram coding (discrete and continuous), and spatial coding. These theories make different predictions regarding the relative similarity of three different types of pairs of letter strings: substitution neighbors,…
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Letter order is not coded by open bigrams
Kinoshita, Sachiko; Norris, Dennis
2013-01-01
Open bigram (OB) models (e.g., SERIOL: Whitney, 2001, 2008; Binary OB, Grainger & van Heuven, 2003; Overlap OB, Grainger et al., 2006; Local combination detector model, Dehaene et al., 2005) posit that letter order in a word is coded by a set of ordered letter pairs. We report three experiments using bigram primes in the same-different match task, investigating the effects of order reversal and the number of letters intervening between the letters in the target. Reversed bigrams (e.g., fo-OF, ob-ABOLISH) produced robust priming, in direct contradiction to the assumption that letter order is coded by the presence of ordered letter pairs. Also in contradiction to the core assumption of current open bigram models, non-contiguous bigrams spanning three letters in the target (e.g., bs-ABOLISH) showed robust priming effects, equivalent in size to contiguous bigrams (e.g., bo-ABOLISH). These results question the role of open bigrams in coding letter order. PMID:23914048
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What Do Letter Migration Errors Reveal About Letter Position Coding in Visual Word Recognition?
ERIC Educational Resources Information Center
Davis, Colin J.; Bowers, Jeffrey S.
2004-01-01
Dividing attention across multiple words occasionally results in misidentifications whereby letters apparently migrate between words. Previous studies have found that letter migrations preserve within-word letter position, which has been interpreted as support for position-specific letter coding. To investigate this issue, the authors used word…
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Parafoveal letter-position coding in reading.
Snell, Joshua; Bertrand, Daisy; Grainger, Jonathan
2018-05-01
The masked-priming lexical decision task has been the paradigm of choice for investigating how readers code for letter identity and position. Insight into the temporal integration of information between prime and target words has pointed out, among other things, that readers do not code for the absolute position of letters. This conception has spurred various accounts of the word recognition process, but the results at present do not favor one account in particular. Thus, employing a new strategy, the present study moves out of the arena of temporal- and into the arena of spatial information integration. We present two lexical decision experiments that tested how the processing of six-letter target words is influenced by simultaneously presented flanking stimuli (each stimulus was presented for 150 ms). We manipulated the orthographic relatedness between the targets and flankers, in terms of both letter identity (same/different letters based on the target's outer/inner letters) and letter position (intact/reversed order of letters and of flankers, contiguous/noncontiguous flankers). Target processing was strongly facilitated by same-letter flankers, and this facilitatory effect was modulated by both letter/flanker order and contiguity. However, when the flankers consisted of the target's inner-positioned letters alone, letter order no longer mattered. These findings suggest that readers may code for the relative position of letters using words' edges as spatial points of reference. We conclude that the flanker paradigm provides a fruitful means to investigate letter-position coding in the fovea and parafovea.
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Simon-type effects: chronometric evidence for keypress schemata in typewriting.
Logan, Gordon D
2003-08-01
In 4 experiments, chronometric evidence for keypress schemata in typing was sought by presenting stimuli to be typed in positions that were displaced from a central fixation point. Reaction times were shorter when stimulus positions corresponded to keyboard locations of the letters to be typed, suggesting that position was an important part of the internal representation of the response. Experiment 1 presented single letters left and right of fixation. Experiment 2 presented single letters above and below fixation. Experiment 3 presented words left and right of fixation and found evidence of parallel activation of keypress schemata. Experiment 4 found no effect of the eccentricity of the keyboard locations and responding fingers, suggesting that response-location codes are categorical, not metric. The results are consistent with D. E. Rumelhart and D. A. Norman's (1982) theory of typewriting.
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Longcamp, Marieke; Anton, Jean-Luc; Roth, Muriel; Velay, Jean-Luc
2005-01-01
In a previous fMRI study on right-handers (Rhrs), we reported that part of the left ventral premotor cortex (BA6) was activated when alphabetical characters were passively observed and that the same region was also involved in handwriting [Longcamp, M., Anton, J. L., Roth, M., & Velay, J. L. (2003). Visual presentation of single letters activates a premotor area involved in writing. NeuroImage, 19, 1492-1500]. We therefore suggested that letter-viewing may induce automatic involvement of handwriting movements. In the present study, in order to confirm this hypothesis, we carried out a similar fMRI experiment on a group of left-handed subjects (Lhrs). We reasoned that if the above assumption was correct, visual perception of letters by Lhrs might automatically activate cortical motor areas coding for left-handed writing movements, i.e., areas located in the right hemisphere. The visual stimuli used here were either single letters, single pseudoletters, or a control stimulus. The subjects were asked to watch these stimuli attentively, and no response was required. The results showed that a ventral premotor cortical area (BA6) in the right hemisphere was specifically activated when Lhrs looked at letters and not at pseudoletters. This right area was symmetrically located with respect to the left one activated under the same circumstances in Rhrs. This finding supports the hypothesis that visual perception of written language evokes covert motor processes. In addition, a bilateral area, also located in the premotor cortex (BA6), but more ventrally and medially, was found to be activated in response to both letters and pseudoletters. This premotor region, which was not activated correspondingly in Rhrs, might be involved in the processing of graphic stimuli, whatever their degree of familiarity.
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''The W and M Are Mixing Me Up'': Use of a Visual Code in Verbal Short-Term Memory Tasks
ERIC Educational Resources Information Center
Best, W.; Howard, D.
2005-01-01
When normal participants are presented with written verbal short-term memory tasks (e.g., remembering a set of letters for immediate spoken recall) there is evidence to suggest that the information is re-coded into phonological form. This paper presents a single case study of MJK whose reading follows the pattern of phonological dyslexia. In…
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Letter position coding across modalities: the case of Braille readers.
Perea, Manuel; García-Chamorro, Cristina; Martín-Suesta, Miguel; Gómez, Pablo
2012-01-01
The question of how the brain encodes letter position in written words has attracted increasing attention in recent years. A number of models have recently been proposed to accommodate the fact that transposed-letter stimuli like jugde or caniso are perceptually very close to their base words. Here we examined how letter position coding is attained in the tactile modality via Braille reading. The idea is that Braille word recognition may provide more serial processing than the visual modality, and this may produce differences in the input coding schemes employed to encode letters in written words. To that end, we conducted a lexical decision experiment with adult Braille readers in which the pseudowords were created by transposing/replacing two letters. We found a word-frequency effect for words. In addition, unlike parallel experiments in the visual modality, we failed to find any clear signs of transposed-letter confusability effects. This dissociation highlights the differences between modalities. The present data argue against models of letter position coding that assume that transposed-letter effects (in the visual modality) occur at a relatively late, abstract locus.
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ERIC Educational Resources Information Center
Tech Directions, 2011
2011-01-01
Cryptology, or cryptography, is the study of writing and deciphering hidden messages in codes, ciphers, and writings. It is almost as old as writing itself. Ciphers are messages in which letters are rearranged or substituted for other letters or numbers. Codes are messages in which letters are replaced by letter groups, syllables, or sentences.…
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Letter Position Coding Across Modalities: The Case of Braille Readers
Perea, Manuel; García-Chamorro, Cristina; Martín-Suesta, Miguel; Gómez, Pablo
2012-01-01
Background The question of how the brain encodes letter position in written words has attracted increasing attention in recent years. A number of models have recently been proposed to accommodate the fact that transposed-letter stimuli like jugde or caniso are perceptually very close to their base words. Methodology Here we examined how letter position coding is attained in the tactile modality via Braille reading. The idea is that Braille word recognition may provide more serial processing than the visual modality, and this may produce differences in the input coding schemes employed to encode letters in written words. To that end, we conducted a lexical decision experiment with adult Braille readers in which the pseudowords were created by transposing/replacing two letters. Principal Findings We found a word-frequency effect for words. In addition, unlike parallel experiments in the visual modality, we failed to find any clear signs of transposed-letter confusability effects. This dissociation highlights the differences between modalities. Conclusions The present data argue against models of letter position coding that assume that transposed-letter effects (in the visual modality) occur at a relatively late, abstract locus. PMID:23071522
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The dependence of frequency distributions on multiple meanings of words, codes and signs
NASA Astrophysics Data System (ADS)
Yan, Xiaoyong; Minnhagen, Petter
2018-01-01
The dependence of the frequency distributions due to multiple meanings of words in a text is investigated by deleting letters. By coding the words with fewer letters the number of meanings per coded word increases. This increase is measured and used as an input in a predictive theory. For a text written in English, the word-frequency distribution is broad and fat-tailed, whereas if the words are only represented by their first letter the distribution becomes exponential. Both distribution are well predicted by the theory, as is the whole sequence obtained by consecutively representing the words by the first L = 6 , 5 , 4 , 3 , 2 , 1 letters. Comparisons of texts written by Chinese characters and the same texts written by letter-codes are made and the similarity of the corresponding frequency-distributions are interpreted as a consequence of the multiple meanings of Chinese characters. This further implies that the difference of the shape for word-frequencies for an English text written by letters and a Chinese text written by Chinese characters is due to the coding and not to the language per se.
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Orthographic Coding: Brain Activation for Letters, Symbols, and Digits.
Carreiras, Manuel; Quiñones, Ileana; Hernández-Cabrera, Juan Andrés; Duñabeitia, Jon Andoni
2015-12-01
The present experiment investigates the input coding mechanisms of 3 common printed characters: letters, numbers, and symbols. Despite research in this area, it is yet unclear whether the identity of these 3 elements is processed through the same or different brain pathways. In addition, some computational models propose that the position-in-string coding of these elements responds to general flexible mechanisms of the visual system that are not character-specific, whereas others suggest that the position coding of letters responds to specific processes that are different from those that guide the position-in-string assignment of other types of visual objects. Here, in an fMRI study, we manipulated character position and character identity through the transposition or substitution of 2 internal elements within strings of 4 elements. Participants were presented with 2 consecutive visual strings and asked to decide whether they were the same or different. The results showed: 1) that some brain areas responded more to letters than to numbers and vice versa, suggesting that processing may follow different brain pathways; 2) that the left parietal cortex is involved in letter identity, and critically in letter position coding, specifically contributing to the early stages of the reading process; and that 3) a stimulus-specific mechanism for letter position coding is operating during orthographic processing. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
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Does Kaniso activate CASINO?: input coding schemes and phonology in visual-word recognition.
Acha, Joana; Perea, Manuel
2010-01-01
Most recent input coding schemes in visual-word recognition assume that letter position coding is orthographic rather than phonological in nature (e.g., SOLAR, open-bigram, SERIOL, and overlap). This assumption has been drawn - in part - by the fact that the transposed-letter effect (e.g., caniso activates CASINO) seems to be (mostly) insensitive to phonological manipulations (e.g., Perea & Carreiras, 2006, 2008; Perea & Pérez, 2009). However, one could argue that the lack of a phonological effect in prior research was due to the fact that the manipulation always occurred in internal letter positions - note that phonological effects tend to be stronger for the initial syllable (Carreiras, Ferrand, Grainger, & Perea, 2005). To reexamine this issue, we conducted a masked priming lexical decision experiment in which we compared the priming effect for transposed-letter pairs (e.g., caniso-CASINO vs. caviro-CASINO) and for pseudohomophone transposed-letter pairs (kaniso-CASINO vs. kaviro-CASINO). Results showed a transposed-letter priming effect for the correctly spelled pairs, but not for the pseudohomophone pairs. This is consistent with the view that letter position coding is (primarily) orthographic in nature.
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Valdois, Sylviane; Lassus-Sangosse, Delphine; Lobier, Muriel
2012-05-01
Poor parallel letter-string processing in developmental dyslexia was taken as evidence of poor visual attention (VA) span, that is, a limitation of visual attentional resources that affects multi-character processing. However, the use of letter stimuli in oral report tasks was challenged on its capacity to highlight a VA span disorder. In particular, report of poor letter/digit-string processing but preserved symbol-string processing was viewed as evidence of poor visual-to-phonology code mapping, in line with the phonological theory of developmental dyslexia. We assessed here the visual-to-phonological-code mapping disorder hypothesis. In Experiment 1, letter-string, digit-string and colour-string processing was assessed to disentangle a phonological versus visual familiarity account of the letter/digit versus symbol dissociation. Against a visual-to-phonological-code mapping disorder but in support of a familiarity account, results showed poor letter/digit-string processing but preserved colour-string processing in dyslexic children. In Experiment 2, two tasks of letter-string report were used, one of which was performed simultaneously to a high-taxing phonological task. Results show that dyslexic children are similarly impaired in letter-string report whether a concurrent phonological task is simultaneously performed or not. Taken together, these results provide strong evidence against a phonological account of poor letter-string processing in developmental dyslexia. Copyright © 2012 John Wiley & Sons, Ltd.
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The use and nature of grapheme coding during sub-lexical processing and lexical access.
Commissaire, Eva; Casalis, Séverine
2018-06-01
This work aimed to investigate grapheme coding during sub-lexical processing and lexical access. Using the letter detection task in Experiment 1, we compared letter pairs that could be considered as a grapheme unit or not depending on context (referred to as weakly cohesive complex, e.g., an in chant vs cane) to real two-letter graphemes (highly cohesive complex, e.g., au in chaud) and single-letter graphemes (simple, e.g., a in place). Three experimental conditions were used, one of which was designed to prevent phonological influences. Data revealed that only highly cohesive complex graphemes were processed as units, not the weakly cohesive ones. The same pattern was found across experimental conditions in favor of an orthographic mechanism. In Experiments 2 and 3, a primed lexical decision task was used with two stimulus onset asynchronies (SOAs) and two different ranges of lexical frequency. We manipulated the number of graphemes removed from partial primes ( d**che vs do**he-DOUCHE) and relatedness. In contrast to Experiment 1, no evidence was provided in favor of a role of graphemes during lexical access. We suggest that graphemes can be conceived as sub-lexical orthographic units per se but can only be captured within a sub-lexical route to reading.
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A dual-route approach to orthographic processing.
Grainger, Jonathan; Ziegler, Johannes C
2011-01-01
In the present theoretical note we examine how different learning constraints, thought to be involved in optimizing the mapping of print to meaning during reading acquisition, might shape the nature of the orthographic code involved in skilled reading. On the one hand, optimization is hypothesized to involve selecting combinations of letters that are the most informative with respect to word identity (diagnosticity constraint), and on the other hand to involve the detection of letter combinations that correspond to pre-existing sublexical phonological and morphological representations (chunking constraint). These two constraints give rise to two different kinds of prelexical orthographic code, a coarse-grained and a fine-grained code, associated with the two routes of a dual-route architecture. Processing along the coarse-grained route optimizes fast access to semantics by using minimal subsets of letters that maximize information with respect to word identity, while coding for approximate within-word letter position independently of letter contiguity. Processing along the fined-grained route, on the other hand, is sensitive to the precise ordering of letters, as well as to position with respect to word beginnings and endings. This enables the chunking of frequently co-occurring contiguous letter combinations that form relevant units for morpho-orthographic processing (prefixes and suffixes) and for the sublexical translation of print to sound (multi-letter graphemes).
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A Dual-Route Approach to Orthographic Processing
Grainger, Jonathan; Ziegler, Johannes C.
2011-01-01
In the present theoretical note we examine how different learning constraints, thought to be involved in optimizing the mapping of print to meaning during reading acquisition, might shape the nature of the orthographic code involved in skilled reading. On the one hand, optimization is hypothesized to involve selecting combinations of letters that are the most informative with respect to word identity (diagnosticity constraint), and on the other hand to involve the detection of letter combinations that correspond to pre-existing sublexical phonological and morphological representations (chunking constraint). These two constraints give rise to two different kinds of prelexical orthographic code, a coarse-grained and a fine-grained code, associated with the two routes of a dual-route architecture. Processing along the coarse-grained route optimizes fast access to semantics by using minimal subsets of letters that maximize information with respect to word identity, while coding for approximate within-word letter position independently of letter contiguity. Processing along the fined-grained route, on the other hand, is sensitive to the precise ordering of letters, as well as to position with respect to word beginnings and endings. This enables the chunking of frequently co-occurring contiguous letter combinations that form relevant units for morpho-orthographic processing (prefixes and suffixes) and for the sublexical translation of print to sound (multi-letter graphemes). PMID:21716577
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Does location uncertainty in letter position coding emerge because of literacy training?
Perea, Manuel; Jiménez, María; Gomez, Pablo
2016-06-01
In the quest to unveil the nature of the orthographic code, a useful strategy is to examine the transposed-letter effect (e.g., JUGDE is more confusable with its base word, JUDGE, than the replacement-letter nonword JUPTE). A leading explanation of this phenomenon, which is line with models of visual attention, is that there is perceptual uncertainty at assigning letters ("objects") to positions. This mechanism would be at work not only with skilled readers but also with preliterate children. An alternative explanation is that the transposed-letter effect emerges at an orthographic level of processing as a direct consequence of literacy training. To test these accounts, we conducted a same-different matching experiment with preliterate 4-year-old children using same versus different trials (created by letter transposition or replacement). Results showed a significantly larger number of false positives (i.e., "same" responses) to transposed-letter strings than to 1/2 replacement-letter strings. Therefore, the present data favor the view that the visual processing of location information is inherently noisy and rule out an interpretation of confusability in letter position coding as emerging from literacy training. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
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47 CFR 2.926 - FCC identifier.
Code of Federal Regulations, 2012 CFR
2012-10-01
... applicant/grantee in the code assignment(s). (c) A grantee code may consist of Arabic numerals, capital... product code assigned by the grantee shall consist of a series of Arabic numerals, capital letters or a combination thereof, and may include the dash or hyphen (-). The total of Arabic numerals, capital letters and...
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47 CFR 2.926 - FCC identifier.
Code of Federal Regulations, 2014 CFR
2014-10-01
... applicant/grantee in the code assignment(s). (c) A grantee code may consist of Arabic numerals, capital... product code assigned by the grantee shall consist of a series of Arabic numerals, capital letters or a combination thereof, and may include the dash or hyphen (-). The total of Arabic numerals, capital letters and...
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47 CFR 2.926 - FCC identifier.
Code of Federal Regulations, 2013 CFR
2013-10-01
... applicant/grantee in the code assignment(s). (c) A grantee code may consist of Arabic numerals, capital... product code assigned by the grantee shall consist of a series of Arabic numerals, capital letters or a combination thereof, and may include the dash or hyphen (-). The total of Arabic numerals, capital letters and...
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49 CFR 173.52 - Classification codes and compatibility groups of explosives.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 2 2014-10-01 2014-10-01 false Classification codes and compatibility groups of... Class 1 § 173.52 Classification codes and compatibility groups of explosives. (a) The classification..., consists of the division number followed by the compatibility group letter. Compatibility group letters are...
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Does Location Uncertainty in Letter Position Coding Emerge Because of Literacy Training?
ERIC Educational Resources Information Center
Perea, Manuel; Jiménez, María; Gomez, Pablo
2016-01-01
In the quest to unveil the nature of the orthographic code, a useful strategy is to examine the transposed-letter effect (e.g., JUGDE is more confusable with its base word, JUDGE, than the replacement-letter nonword JUPTE). A leading explanation of this phenomenon, which is in line with models of visual attention, is that there is perceptual…
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Pirates at Parties: Letter Position Processing in Developing Readers
ERIC Educational Resources Information Center
Kohnen, Saskia; Castles, Anne
2013-01-01
There has been much recent interest in letter position coding in adults, but little is known about the development of this process in children learning to read. Here, the letter position coding abilities of 127 children in Grades 2, 3, and 4 (aged 7-10 years) were examined by comparing their performance in reading aloud "migratable" words (e.g.,…
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Perea, Manuel; Acha, Joana
2009-02-01
Recently, a number of input coding schemes (e.g., SOLAR model, SERIOL model, open-bigram model, overlap model) have been proposed that capture the transposed-letter priming effect (i.e., faster response times for jugde-JUDGE than for jupte-JUDGE). In their current version, these coding schemes do not assume any processing differences between vowels and consonants. However, in a lexical decision task, Perea and Lupker (2004, JML; Lupker, Perea, & Davis, 2008, L&CP) reported that transposed-letter priming effects occurred for consonant transpositions but not for vowel transpositions. This finding poses a challenge for these recently proposed coding schemes. Here, we report four masked priming experiments that examine whether this consonant/vowel dissociation in transposed-letter priming is task-specific. In Experiment 1, we used a lexical decision task and found a transposed-letter priming effect only for consonant transpositions. In Experiments 2-4, we employed a same-different task - a task which taps early perceptual processes - and found a robust transposed-letter priming effect that did not interact with consonant/vowel status. We examine the implications of these findings for the front-end of the models of visual word recognition.
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A Stimulus Sampling Theory of Letter Identity and Order
ERIC Educational Resources Information Center
Norris, Dennis; Kinoshita, Sachiko; van Casteren, Maarten
2010-01-01
Early on during word recognition, letter positions are not accurately coded. Evidence for this comes from transposed-letter (TL) priming effects, in which letter strings generated by transposing two adjacent letters (e.g., "jugde") produce large priming effects, more than primes with the letters replaced in the corresponding position (e.g.,…
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Perea, Manuel; Jiménez, María; Martín-Suesta, Miguel; Gómez, Pablo
2015-04-01
This article explores how letter position coding is attained during braille reading and its implications for models of word recognition. When text is presented visually, the reading process easily adjusts to the jumbling of some letters (jugde-judge), with a small cost in reading speed. Two explanations have been proposed: One relies on a general mechanism of perceptual uncertainty at the visual level, and the other focuses on the activation of an abstract level of representation (i.e., bigrams) that is shared by all orthographic codes. Thus, these explanations make differential predictions about reading in a tactile modality. In the present study, congenitally blind readers read sentences presented on a braille display that tracked the finger position. The sentences either were intact or involved letter transpositions. A parallel experiment was conducted in the visual modality. Results revealed a substantially greater reading cost for the sentences with transposed-letter words in braille readers. In contrast with the findings with sighted readers, in which there is a cost of transpositions in the external (initial and final) letters, the reading cost in braille readers occurs serially, with a large cost for initial letter transpositions. Thus, these data suggest that the letter-position-related effects in visual word recognition are due to the characteristics of the visual stream.
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Kawano, Tomonori
2013-03-01
There have been a wide variety of approaches for handling the pieces of DNA as the "unplugged" tools for digital information storage and processing, including a series of studies applied to the security-related area, such as DNA-based digital barcodes, water marks and cryptography. In the present article, novel designs of artificial genes as the media for storing the digitally compressed data for images are proposed for bio-computing purpose while natural genes principally encode for proteins. Furthermore, the proposed system allows cryptographical application of DNA through biochemically editable designs with capacity for steganographical numeric data embedment. As a model case of image-coding DNA technique application, numerically and biochemically combined protocols are employed for ciphering the given "passwords" and/or secret numbers using DNA sequences. The "passwords" of interest were decomposed into single letters and translated into the font image coded on the separate DNA chains with both the coding regions in which the images are encoded based on the novel run-length encoding rule, and the non-coding regions designed for biochemical editing and the remodeling processes revealing the hidden orientation of letters composing the original "passwords." The latter processes require the molecular biological tools for digestion and ligation of the fragmented DNA molecules targeting at the polymerase chain reaction-engineered termini of the chains. Lastly, additional protocols for steganographical overwriting of the numeric data of interests over the image-coding DNA are also discussed.
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Sudoku Puzzles for First-Year Organic Chemistry Students
ERIC Educational Resources Information Center
Perez, Alice L.; Lamoureux, G.
2007-01-01
Sudoku puzzle was designed to teach about amino acids and functional groups to the students of undergraduate organic chemistry students. The puzzles focus on helping the student learn the name, 3-letter code and 1-letter code of common amino acids and functional groups.
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ERIC Educational Resources Information Center
Kezilas, Yvette; McKague, Meredith; Kohnen, Saskia; Badcock, Nicholas A.; Castles, Anne
2017-01-01
Masked transposed-letter (TL) priming effects have been used to index letter position processing over the course of reading development. Whereas some studies have reported an increase in TL priming over development, others have reported a decrease. These findings have led to the development of 2 somewhat contradictory accounts of letter position…
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NASA Astrophysics Data System (ADS)
Trejos, Sorayda; Fredy Barrera, John; Torroba, Roberto
2015-08-01
We present for the first time an optical encrypting-decrypting protocol for recovering messages without speckle noise. This is a digital holographic technique using a 2f scheme to process QR codes entries. In the procedure, letters used to compose eventual messages are individually converted into a QR code, and then each QR code is divided into portions. Through a holographic technique, we store each processed portion. After filtering and repositioning, we add all processed data to create a single pack, thus simplifying the handling and recovery of multiple QR code images, representing the first multiplexing procedure applied to processed QR codes. All QR codes are recovered in a single step and in the same plane, showing neither cross-talk nor noise problems as in other methods. Experiments have been conducted using an interferometric configuration and comparisons between unprocessed and recovered QR codes have been performed, showing differences between them due to the involved processing. Recovered QR codes can be successfully scanned, thanks to their noise tolerance. Finally, the appropriate sequence in the scanning of the recovered QR codes brings a noiseless retrieved message. Additionally, to procure maximum security, the multiplexed pack could be multiplied by a digital diffuser as to encrypt it. The encrypted pack is easily decoded by multiplying the multiplexing with the complex conjugate of the diffuser. As it is a digital operation, no noise is added. Therefore, this technique is threefold robust, involving multiplexing, encryption, and the need of a sequence to retrieve the outcome.
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ERIC Educational Resources Information Center
Byrum, John D.
This paper describes two international standards for the representation of the names of languages. The first (ISO 639-1), published in 1988, provides two-letter codes for 136 languages and was produced primarily to meet terminological needs. The second (ISO 639-2) appeared in late 1998 and includes three-letter codes for 460 languages. This list…
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Kawano, Tomonori
2013-01-01
There have been a wide variety of approaches for handling the pieces of DNA as the “unplugged” tools for digital information storage and processing, including a series of studies applied to the security-related area, such as DNA-based digital barcodes, water marks and cryptography. In the present article, novel designs of artificial genes as the media for storing the digitally compressed data for images are proposed for bio-computing purpose while natural genes principally encode for proteins. Furthermore, the proposed system allows cryptographical application of DNA through biochemically editable designs with capacity for steganographical numeric data embedment. As a model case of image-coding DNA technique application, numerically and biochemically combined protocols are employed for ciphering the given “passwords” and/or secret numbers using DNA sequences. The “passwords” of interest were decomposed into single letters and translated into the font image coded on the separate DNA chains with both the coding regions in which the images are encoded based on the novel run-length encoding rule, and the non-coding regions designed for biochemical editing and the remodeling processes revealing the hidden orientation of letters composing the original “passwords.” The latter processes require the molecular biological tools for digestion and ligation of the fragmented DNA molecules targeting at the polymerase chain reaction-engineered termini of the chains. Lastly, additional protocols for steganographical overwriting of the numeric data of interests over the image-coding DNA are also discussed. PMID:23750303
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76 FR 7864 - Agency Information Collection Activities: Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-11
...: Psychiatric Unit Criteria Work Sheet and Supporting Regulations 412.25 and 412.27; Use: A limited number of... National Correct Coding Initiative in Medicaid, SMD Letter 10-017 dated September 1, 2010. Use; The Patient... State Use of National Correct Coding Initiative. A State Medicaid Director letter, 10-017 dated...
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"What" and "where" in word reading: ventral coding of written words revealed by parietal atrophy.
Vinckier, Fabien; Naccache, Lionel; Papeix, Caroline; Forget, Joaquim; Hahn-Barma, Valerie; Dehaene, Stanislas; Cohen, Laurent
2006-12-01
The visual system of literate adults develops a remarkable perceptual expertise for printed words. To delineate the aspects of this competence intrinsic to the occipitotemporal "what" pathway, we studied a patient with bilateral lesions of the occipitoparietal "where" pathway. Depending on critical geometric features of the display (rotation angle, letter spacing, mirror reversal, etc.), she switched from a good performance, when her intact ventral pathway was sufficient to encode words, to severely impaired reading, when her parietal lesions prevented the use of alternative reading strategies as a result of spatial and attentional impairments. In particular, reading was disrupted (a) by rotating word by more than 50 degrees , providing an approximation of the invariance range for words encoding in the ventral pathway; (b) by separating letters with double spaces, revealing the limits of letter grouping into perceptual wholes; (c) by mirror-reversing words, showing that words escape the default mirror-invariant representation of visual objects in the ventral pathway. Moreover, because of her parietal lesions, she was unable to discriminate mirror images of common objects, although she was excellent with reversible pseudowords, confirming that the breaking of mirror symmetry was intrinsic to the occipitotemporal cortex. Thus, charting the display conditions associated with preserved or impaired performance allowed us to infer properties of word coding in the normal ventral pathway and to delineate the roles of the parietal lobes in single-word recognition.
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ERIC Educational Resources Information Center
Kim, Young-Suk; Al Otaiba, Stephanie; Puranik, Cynthia; Folsom, Jessica Sidler; Gruelich, Luana
2014-01-01
In the present study we examined the relation between alphabet knowledge fluency (letter names and sounds) and letter writing automaticity, and unique relations of letter writing automaticity and semantic knowledge (i.e., vocabulary) to word reading and spelling over and above code-related skills such as phonological awareness and alphabet…
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Comesaña, Montserrat; Soares, Ana P; Marcet, Ana; Perea, Manuel
2016-11-01
In skilled adult readers, transposed-letter effects (jugde-JUDGE) are greater for consonant than for vowel transpositions. These differences are often attributed to phonological rather than orthographic processing. To examine this issue, we employed a scenario in which phonological involvement varies as a function of reading experience: A masked priming lexical decision task with 50-ms primes in adult and developing readers. Indeed, masked phonological priming at this prime duration has been consistently reported in adults, but not in developing readers (Davis, Castles, & Iakovidis, 1998). Thus, if consonant/vowel asymmetries in letter position coding with adults are due to phonological influences, transposed-letter priming should occur for both consonant and vowel transpositions in developing readers. Results with adults (Experiment 1) replicated the usual consonant/vowel asymmetry in transposed-letter priming. In contrast, no signs of an asymmetry were found with developing readers (Experiments 2-3). However, Experiments 1-3 did not directly test the existence of phonological involvement. To study this question, Experiment 4 manipulated the phonological prime-target relationship in developing readers. As expected, we found no signs of masked phonological priming. Thus, the present data favour an interpretation of the consonant/vowel dissociation in letter position coding as due to phonological rather than orthographic processing. © 2016 The British Psychological Society.
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ERIC Educational Resources Information Center
Jeon, Seong Taek; Hamid, Joshua; Maurer, Daphne; Lewis, Terri L.
2010-01-01
Crowding refers to impaired target recognition caused by surrounding contours. We investigated the development of crowding in central vision by comparing single-letter and crowding thresholds in groups of 5-year-olds, 8-year-olds, 11-year-olds, and adults. The task was to discriminate the orientation of a Sloan letter E. Single-letter thresholds,…
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Reading through a Noisy Channel: Why There's Nothing Special about the Perception of Orthography
ERIC Educational Resources Information Center
Norris, Dennis; Kinoshita, Sachiko
2012-01-01
The goal of research on how letter identity and order are perceived during reading is often characterized as one of "cracking the orthographic code." Here, we suggest that there is no orthographic code to crack: Words are perceived and represented as sequences of letters, just as in a dictionary. Indeed, words are perceived and represented in…
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Action and perception in literacy: A common-code for spelling and reading.
Houghton, George
2018-01-01
There is strong evidence that reading and spelling in alphabetical scripts depend on a shared representation (common-coding). However, computational models usually treat the two skills separately, producing a wide variety of proposals as to how the identity and position of letters is represented. This article treats reading and spelling in terms of the common-coding hypothesis for perception-action coupling. Empirical evidence for common representations in spelling-reading is reviewed. A novel version of the Start-End Competitive Queuing (SE-CQ) spelling model is introduced, and tested against the distribution of positional errors in Letter Position Dysgraphia, data from intralist intrusion errors in spelling to dictation, and dysgraphia because of nonperipheral neglect. It is argued that no other current model is equally capable of explaining this range of data. To pursue the common-coding hypothesis, the representation used in SE-CQ is applied, without modification, to the coding of letter identity and position for reading and lexical access, and a lexical matching rule for the representation is proposed (Start End Position Code model, SE-PC). Simulations show the model's compatibility with benchmark findings from form priming, its ability to account for positional effects in letter identification priming and the positional distribution of perseverative intrusion errors. The model supports the view that spelling and reading use a common orthographic description, providing a well-defined account of the major features of this representation. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
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Lerner, Matthew D.; Lonigan, Christopher J.
2017-01-01
Despite the importance of phonological awareness for the development of reading in alphabetic languages, little attention has been paid to its developmental origins. In this study, dual-process, latent growth models were used to examine patterns of bidirectional relations between letter knowledge and phonological awareness during preschool. The sample comprised 358 children (mean age = 48.60 months, SD = 7.26). Growth models were used to quantify the unique longitudinal relations between the initial level of each skill and growth in the other skill during the preschool year, after controlling for initial level of the same skill, vocabulary, age, and growth in the code-related skill being used as a predictor. Letter-name knowledge and phonological awareness were bi-directionally related; the initial level of each uniquely predicted growth in the other. Initial letter-sound knowledge and phonological awareness growth were not uniquely related, and vocabulary was not related to growth in phonological awareness. These findings extend the evidence of the relation between letter knowledge and phonological awareness to supra-phonemic tasks, indicating that this bidirectional relation begins at an earlier point in the development of phonological awareness than previously reported. In addition, these findings help to rule out general growth in letter knowledge and phonological awareness as an alternative explanation for the bidirectional relation between these two code-related skills. PMID:26745710
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Flexible letter-position coding is unlikely to hold for morphologically rich languages.
Hyönä, Jukka; Bertram, Raymond
2012-10-01
We agree with Frost that flexible letter-position coding is unlikely to be a universal property of word recognition across different orthographies. We argue that it is particularly unlikely in morphologically rich languages like Finnish. We also argue that dual-route models are not overly flexible and that they are well equipped to adapt to the linguistic environment at hand.
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75 FR 4693 - New Postal Product
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-29
... Post Group exceed six times the rate for the first ounce of a First-Class Mail letter. Id., para. (e... Dominant Products 1000 Market Dominant Product List First-Class Mail Single-Piece Letters/Postcards Bulk Letters/Postcards Flats Parcels Outbound Single-Piece First-Class Mail International Inbound Single-Piece...
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Rooted tRNAomes and evolution of the genetic code
Pak, Daewoo; Du, Nan; Kim, Yunsoo; Sun, Yanni
2018-01-01
ABSTRACT We advocate for a tRNA- rather than an mRNA-centric model for evolution of the genetic code. The mechanism for evolution of cloverleaf tRNA provides a root sequence for radiation of tRNAs and suggests a simplified understanding of code evolution. To analyze code sectoring, rooted tRNAomes were compared for several archaeal and one bacterial species. Rooting of tRNAome trees reveals conserved structures, indicating how the code was shaped during evolution and suggesting a model for evolution of a LUCA tRNAome tree. We propose the polyglycine hypothesis that the initial product of the genetic code may have been short chain polyglycine to stabilize protocells. In order to describe how anticodons were allotted in evolution, the sectoring-degeneracy hypothesis is proposed. Based on sectoring, a simple stepwise model is developed, in which the code sectors from a 1→4→8→∼16 letter code. At initial stages of code evolution, we posit strong positive selection for wobble base ambiguity, supporting convergence to 4-codon sectors and ∼16 letters. In a later stage, ∼5–6 letters, including stops, were added through innovating at the anticodon wobble position. In archaea and bacteria, tRNA wobble adenine is negatively selected, shrinking the maximum size of the primordial genetic code to 48 anticodons. Because 64 codons are recognized in mRNA, tRNA-mRNA coevolution requires tRNA wobble position ambiguity leading to degeneracy of the code. PMID:29372672
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Pacific Northwest (PNW) Hydrologic Landscape (HL) polygons and HL code
A five-letter hydrologic landscape code representing five indices of hydrologic form that are related to hydrologic function: climate, seasonality, aquifer permeability, terrain, and soil permeability. Each hydrologic assessment unit is classified by one of the 81 different five-letter codes representing these indices. Polygon features in this dataset were created by aggregating (dissolving boundaries between) adjacent, similarly-coded hydrologic assessment units. Climate Classes: V-Very wet, W-Wet, M-Moist, D-Dry, S-Semiarid, A-Arid. Seasonality Sub-Classes: w-Fall or winter, s-Spring. Aquifer Permeability Classes: H-High, L-Low. Terrain Classes: M-Mountain, T-Transitional, F-Flat. Soil Permeability Classes: H-High, L-Low.
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What can we learn from learning models about sensitivity to letter-order in visual word recognition?
Lerner, Itamar; Armstrong, Blair C.; Frost, Ram
2014-01-01
Recent research on the effects of letter transposition in Indo-European Languages has shown that readers are surprisingly tolerant of these manipulations in a range of tasks. This evidence has motivated the development of new computational models of reading that regard flexibility in positional coding to be a core and universal principle of the reading process. Here we argue that such approach does not capture cross-linguistic differences in transposed-letter effects, nor do they explain them. To address this issue, we investigated how a simple domain-general connectionist architecture performs in tasks such as letter-transposition and letter substitution when it had learned to process words in the context of different linguistic environments. The results show that in spite of of the neurobiological noise involved in registering letter-position in all languages, flexibility and inflexibility in coding letter order is also shaped by the statistical orthographic properties of words in a language, such as the relative prevalence of anagrams. Our learning model also generated novel predictions for targeted empirical research, demonstrating a clear advantage of learning models for studying visual word recognition. PMID:25431521
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Single-pixel imaging based on compressive sensing with spectral-domain optical mixing
NASA Astrophysics Data System (ADS)
Zhu, Zhijing; Chi, Hao; Jin, Tao; Zheng, Shilie; Jin, Xiaofeng; Zhang, Xianmin
2017-11-01
In this letter a single-pixel imaging structure is proposed based on compressive sensing using a spatial light modulator (SLM)-based spectrum shaper. In the approach, an SLM-based spectrum shaper, the pattern of which is a predetermined pseudorandom bit sequence (PRBS), spectrally codes the optical pulse carrying image information. The energy of the spectrally mixed pulse is detected by a single-pixel photodiode and the measurement results are used to reconstruct the image via a sparse recovery algorithm. As the mixing of the image signal and the PRBS is performed in the spectral domain, optical pulse stretching, modulation, compression and synchronization in the time domain are avoided. Experiments are implemented to verify the feasibility of the approach.
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The Overlap Model: A Model of Letter Position Coding
ERIC Educational Resources Information Center
Gomez, Pablo; Ratcliff, Roger; Perea, Manuel
2008-01-01
Recent research has shown that letter identity and letter position are not integral perceptual dimensions (e.g., jugde primes judge in word-recognition experiments). Most comprehensive computational models of visual word recognition (e.g., the interactive activation model, J. L. McClelland & D. E. Rumelhart, 1981, and its successors) assume that…
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ERIC Educational Resources Information Center
Valdois, Sylviane; Lassus-Sangosse, Delphine; Lobier, Muriel
2012-01-01
Poor parallel letter-string processing in developmental dyslexia was taken as evidence of poor visual attention (VA) span, that is, a limitation of visual attentional resources that affects multi-character processing. However, the use of letter stimuli in oral report tasks was challenged on its capacity to highlight a VA span disorder. In…
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49 CFR 178.910 - Marking of Large Packagings.
Code of Federal Regulations, 2014 CFR
2014-10-01
... stamped or embossed, the capital letters “UN” may be applied instead of the symbol; (ii) The code number...) The country authorizing the allocation of the mark. The letters “USA” indicate that the Large...
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49 CFR 178.910 - Marking of Large Packagings.
Code of Federal Regulations, 2013 CFR
2013-10-01
... stamped or embossed, the capital letters “UN” may be applied instead of the symbol; (ii) The code number...) The country authorizing the allocation of the mark. The letters “USA” indicate that the Large...
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Giaschi, D; Regan, D
1997-09-01
Three-month-old infants can discriminate motion-defined (MD) form, but we do not know the age at which this ability reaches adult levels. Previous psychophysical evidence suggests that different neural mechanisms are involved in the processing of luminance-defined (LD) and MD spatial form in adults. This difference may be reflected in the development of LD versus MD form identification in children. We measured speed threshold for identifying MD letters, letter-chart (i.e, Snellen) acuity for high-contrast LD letters and single-letter acuity for high- and low-contrast LD letters. Forty-seven children between 3 and 12 years of age and 20 adult subjects were tested. Development to the adult level was observed as follows: low-contrast single-letter acuity before 3 years; high-contrast single-letter acuity by 5 to 6 years; the ability to identify MD letters by 7 to 8 years; letter-chart acuity by 9 to 10 years. MD form identification continues to mature in preschool children. LD form identification also matures in this age group but with a different time course. MD letters are not equivalent to low-contrast letters developmentally. Our findings provide further support for the hypothesis that the spatial aspects of MD and LD form are processed separately to some extent.
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Target--distractor separation and feature integration in visual attention to letters.
Driver, J; Baylis, G C
1991-04-01
The interference produced by distractor letters diminishes with increasing distance from a target letter, as if the distractors fall outside an attentional spotlight focussed on the target (Eriksen and Eriksen 1974). We examine Hagenaar and Van der Heijden's (1986) claim that this distance effect is an acuity artefact. Feature integration theory (Treisman 1986) predicts that even when acuity is controlled for, distance effects should be found when interference is produced by conjoined distractor features (e.g. letter-identities), but not when interference arises from isolated distractor features (e.g. letter-strokes). The opposite pattern of results is found. A model is proposed in which both letter-strokes and letter-identities are derived in parallel. The location of letter-strokes can also be coded in parallel, but locating letter-identities may require the operation of attention.
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Don't words come easy? A psychophysical exploration of word superiority
Starrfelt, Randi; Petersen, Anders; Vangkilde, Signe
2013-01-01
Words are made of letters, and yet sometimes it is easier to identify a word than a single letter. This word superiority effect (WSE) has been observed when written stimuli are presented very briefly or degraded by visual noise. We compare performance with letters and words in three experiments, to explore the extents and limits of the WSE. Using a carefully controlled list of three letter words, we show that a WSE can be revealed in vocal reaction times even to undegraded stimuli. With a novel combination of psychophysics and mathematical modeling, we further show that the typical WSE is specifically reflected in perceptual processing speed: single words are simply processed faster than single letters. Intriguingly, when multiple stimuli are presented simultaneously, letters are perceived more easily than words, and this is reflected both in perceptual processing speed and visual short term memory (VSTM) capacity. So, even if single words come easy, there is a limit to the WSE. PMID:24027510
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Transposed-letter priming of prelexical orthographic representations.
Kinoshita, Sachiko; Norris, Dennis
2009-01-01
A prime generated by transposing two internal letters (e.g., jugde) produces strong priming of the original word (judge). In lexical decision, this transposed-letter (TL) priming effect is generally weak or absent for nonword targets; thus, it is unclear whether the origin of this effect is lexical or prelexical. The authors describe the Bayesian Reader theory of masked priming (D. Norris & S. Kinoshita, 2008), which explains why nonwords do not show priming in lexical decision but why they do in the cross-case same-different task. This analysis is followed by 3 experiments that show that priming in this task is not based on low-level perceptual similarity between the prime and target, or on phonology, to make the case that priming is based on prelexical orthographic representation. The authors then use this task to demonstrate equivalent TL priming effects for nonwords and words. The results are interpreted as the first reliable evidence based on the masked priming procedure that letter position is not coded absolutely within the prelexical, orthographic representation. The implications of the results for current letter position coding schemes are discussed.
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75 FR 3988 - New Postal Product
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-26
... agreement may contain letters, the prices paid under the agreement are higher than six times the rate for the current price of a one-ounce, single-piece First-Class Mail letter. Id., para. (e). It also...--Market Dominant Products 1000 Market Dominant Product List First-Class Mail Single-Piece Letters...
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The elaboration of motor programs for the automation of letter production.
Thibon, Laurence Séraphin; Gerber, Silvain; Kandel, Sonia
2018-01-01
We investigated how children learn to write letters. Letter writing evolves from stroke-by-stroke to whole-letter programming. Children of ages 6 to 9 (N=98) wrote letters of varying complexity on a digitizer. At ages 6 and 7 movement duration, dysfluency and trajectory increased with stroke number. This indicates that the motor program they activated mainly coded information on stroke production. Stroke number affected the older children's production much less, suggesting that they programmed stroke chunks or the whole letter. The fact that movement duration and dysfluency decreased from ages 6 to 8, and remained stable at ages 8 and 9 suggests that automation of letter writing begins at age 8. Automation seems to require the elaboration of stroke chunks and/or letter-sized motor programs. Copyright © 2017 Elsevier B.V. All rights reserved.
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Minimizing embedding impact in steganography using trellis-coded quantization
NASA Astrophysics Data System (ADS)
Filler, Tomáš; Judas, Jan; Fridrich, Jessica
2010-01-01
In this paper, we propose a practical approach to minimizing embedding impact in steganography based on syndrome coding and trellis-coded quantization and contrast its performance with bounds derived from appropriate rate-distortion bounds. We assume that each cover element can be assigned a positive scalar expressing the impact of making an embedding change at that element (single-letter distortion). The problem is to embed a given payload with minimal possible average embedding impact. This task, which can be viewed as a generalization of matrix embedding or writing on wet paper, has been approached using heuristic and suboptimal tools in the past. Here, we propose a fast and very versatile solution to this problem that can theoretically achieve performance arbitrarily close to the bound. It is based on syndrome coding using linear convolutional codes with the optimal binary quantizer implemented using the Viterbi algorithm run in the dual domain. The complexity and memory requirements of the embedding algorithm are linear w.r.t. the number of cover elements. For practitioners, we include detailed algorithms for finding good codes and their implementation. Finally, we report extensive experimental results for a large set of relative payloads and for different distortion profiles, including the wet paper channel.
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[The role of external letter positions in visual word recognition].
Perea, Manuel; Lupker, Sthephen J
2007-11-01
A key issue for any computational model of visual word recognition is the choice of an input coding schema, which is responsible for assigning letter positions. Such a schema must reflect the fact that, according to recent research, nonwords created by transposing letters (e.g., caniso for CASINO ), typically, appear to be more similar to the word than nonwords created by replacing letters (e.g., caviro ). In the present research, we initially carried out a computational analysis examining the degree to which the position of the transposition influences transposed-letter similarity effects. We next conducted a masked priming experiment with the lexical decision task to determine whether a transposed-letter priming advantage occurs when the first letter position is involved. Primes were created by either transposing the first and third letters (démula-MEDULA ) or replacing the first and third letters (bérula-MEDULA). Results showed that there was no transposed-letter priming advantage in this situation. We discuss the implications of these results for models of visual word recognition.
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ERIC Educational Resources Information Center
Grosser, George S.; Trzeciak, Gerda M.
1981-01-01
Two sets of letters, those subject to reversal/rotation and others, were tachistoscopically presented singly to normal readers and dyslexic children. The data support the hypothesis that letters subject to reversal have no special relation to dyslexia. The view that dyslexia is a developmental anomaly was supported. (Author/AL)
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A measure of short-term visual memory based on the WISC-R coding subtest.
Collaer, M L; Evans, J R
1982-07-01
Adapted the Coding subtest of the WISC-R to provide a measure of visual memory. Three hundred and five children, aged 8 through 12, were administered the Coding test using standard directions. A few seconds after completion the key was taken away, and each was given a paper with only the digits and asked to write the appropriate matching symbol below each. This was termed "Coding Recall." To provide validity data, a subgroup of 50 Ss also was administered the Attention Span for Letters subtest from the Detroit Tests of Learning Aptitude (as a test of visual memory for sequences of letters) and a Bender Gestalt recall test (as a measure of visual memory for geometric forms). Coding Recall means and standard deviations are reported separately by sex and age level. Implications for clinicans are discussed. Reservations about clinical use of the data are given in view of the possible lack of representativeness of the sample used and the limited reliability and validity of Coding Recall.
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Pacific Northwest ecoclass codes for seral and potential natural communities.
Frederick C. Hall
1998-01-01
Lists codes for identification of potential natural communities (plant association, habitat types), their seral status, and vegetation structure in and around the Pacific Northwest. Codes are a six-digit alphanumeric system using the first letter of tree species, life-form, seral status, and structure so that most codes can be directly interpreted. Seven appendices...
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Using Incremental Rehearsal to Teach Letter Sounds to English Language Learners
ERIC Educational Resources Information Center
Rahn, Naomi L.; Wilson, Jennifer; Egan, Andrea; Brandes, Dana; Kunkel, Amy; Peterson, Meredith; McComas, Jennifer
2015-01-01
This study examined the effects of incremental rehearsal (IR) on letter sound expression for one kindergarten and one first grade English learner who were below district benchmark for letter sound fluency. A single-subject multiple-baseline design across sets of unknown letter sounds was used to evaluate the effect of IR on letter-sound expression…
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Development of Early Handwriting: Visual-Motor Control During Letter Copying
Maldarelli, Jennifer E.; Kahrs, Björn A.; Hunt, Sarah C.; Lockman, Jeffrey J.
2015-01-01
Despite the importance of handwriting for school readiness and early academic progress, prior research on the development of handwriting has focused primarily on the product rather than the process by which young children write letters. In contrast, in the present work, early handwriting is viewed as involving a suite of perceptual, motor and cognitive abilities, which must work in unison if children are to write letters efficiently. To study such coordination, head-mounted eye-tracking technology was used to investigate the process of visual-motor coordination while kindergarten children (N=23) and adults (N=11) copied individual letters and strings of letters that differed in terms of their phonemic properties. Results indicated that kindergarten children were able to copy single letters efficiently, as did adults. When the cognitive demands of the task increased and children were presented with strings of letters, however, their ability to copy letters efficiently was compromised: children frequently interrupted their writing mid-letter, whereas they did not do so on single letter trials. Yet, with increasing age, children became more efficient in copying letter strings, in part by using vision more prospectively when writing. Taken together, the results illustrate how the coordination of perceptual, motor and cognitive processes contributes to advances in the development of letter writing skill. PMID:26029821
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A versus F: the effects of implicit letter priming on cognitive performance.
Ciani, Keith D; Sheldon, Kennon M
2010-03-01
It has been proposed that motivational responses outside people's conscious awareness can be primed to affect academic performance. The current research focused on the relationship between primed evaluative letters (A and F), explicit and implicit achievement motivation, and cognitive performance. Given the evaluative connotation associated with letter grades, we wanted to know if exposure to the letter A before a task could improve performance, and exposure to the letter F could impair performance. If such effects are found, we suspected that they may be rooted in implicit approach versus avoidance motivation, and occur without participants' awareness. The current research was conducted at a large research university in the USA. Twenty-three undergraduates participated in Expt 1, 32 graduate students in Expt 2, and 76 undergraduates in Expt 3. Expts 1 and 2 were conducted in classroom settings, and Expt 3 in a laboratory. In Expt 1, participants were randomly assigned to either the A or F condition. The letter manipulation came in the form of an ostensible Test Bank ID code on the cover of an analogy test, which participants were prompted to view and write on each page of their test. Expt 2 followed a similar procedure but included the neutral letter J as a third condition to serve as a control. In Expt 3, participants' letter condition was presented in the form of an ostensible Subject ID code prior to an anagram test. Expts 1-3 demonstrated that exposure to the letter A enhances performance relative to the exposure to the letter F, whereas exposure to the letter F prior to an achievement task can impair performance. This effect was demonstrated using two different types of samples (undergraduate and graduate students), in two different experimental settings (classroom and laboratory), using two different types of achievement tasks (analogy and anagram), and using two different types of letter presentation (Test Bank ID and Subject ID). Results from the funnelled debriefing, self-report goals, and word-stem completion support our position that the effect of letter on academic performance takes place outside the conscious awareness of participants. Our findings suggest that students are vulnerable to evaluative letters presented before a task, and support years of research highlighting the significant role that nonconscious processes play in achievement settings.
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Good Phonic Generalizations for Decoding
ERIC Educational Resources Information Center
Gates, Louis
2007-01-01
An exhaustive analysis of 88,641 individual letters and letter combinations within 16,928 words drawn from the Zeno, et al. word list unveiled remarkable phonic transparency. The individual letter and letter combinations sorted into just six general categories: three basic categories of vowels (single vowels, vowel digraphs, and final…
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78 FR 19288 - Letters of Authorization To Take Marine Mammals
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-29
.... ACTION: Notice of Issuance. SUMMARY: In accordance with the Marine Mammal Protection Act of 1972, as... of title 50 of the Code of Federal Regulations (CFR) and is effective through August 3, 2016. The... following companies in the Beaufort Sea and adjacent northern coast of Alaska: Beaufort Sea Letters of...
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USSR Space Life Sciences Digest. Index to issues 1-4
NASA Technical Reports Server (NTRS)
Teeter, R.; Hooke, L. R.
1986-01-01
This document is an index to issues 1 to 4 of the USSR Space Life Sciences Digest and is arranged in three sections. In section 1, abstracts from the first four issues are grouped according to subject; please note the four letter codes in the upper right hand corner of the pages. Section 2 lists the categories according to which digest entries are grouped and cites additional entries relevant to that category by four letter code and entry number in section 1. Refer to section 1 for titles and other pertinent information. Key words are indexed in section 3.
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Mosser, Joy; Lee, Grace; Pootrakul, Llana; Harfmann, Katya; Fabbro, Stephanie; Faith, Esteban Fernandez; Carr, David; Plotner, Alisha; Zirwas, Matthew; Kaffenberger, Benjamin H.
2016-01-01
Background: In an effort to avoid numerous problems associated with narrative letters of recommendation, a dermatology standardized letter of recommendation was utilized in the 2014–2015 resident application cycle. Objective: A comparison of the standardized letter of recommendation and narrative letters of recommendation from a single institution and application cycle to determine if the standardized letter of recommendation met its original goals of efficiency, applicant stratification, and validity. Methods: Eight dermatologists assessed all standardized letters of recommendation/narrative letters of recommendation pairs received during the 2014–2015 application cycle. Five readers repeated the analysis two months later. Each letter of recommendation was evaluated based on a seven question survey. Letter analysis and survey completion for each letter was timed. Results: Compared to the narrative letters of recommendation, the standardized letter of recommendation is easier to interpret (p<0.0001), has less exaggeration of applicants’ positive traits (p<0.001), and has higher inter-rater and intrarater reliability for determining applicant traits including personality, reliability, work-ethic, and global score. Standardized letters of recommendation are also faster to interpret (p<0.0001) and provide more information about the writer’s background or writer-applicant relationship than narrative letters of recommendation (p<0.001). Limitations: This study was completed at a single institution. Conclusions: The standardized letter of recommendation appears to be meeting its initial goals of 1) efficiency, 2) applicant stratification, and 3) validity. (J Clin Aesthet Dermatol. 2016;9(9):36–2.) PMID:27878060
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Reading Visual Braille with a Retinal Prosthesis
Lauritzen, Thomas Z.; Harris, Jordan; Mohand-Said, Saddek; Sahel, Jose A.; Dorn, Jessy D.; McClure, Kelly; Greenberg, Robert J.
2012-01-01
Retinal prostheses, which restore partial vision to patients blinded by outer retinal degeneration, are currently in clinical trial. The Argus II retinal prosthesis system was recently awarded CE approval for commercial use in Europe. While retinal prosthesis users have achieved remarkable visual improvement to the point of reading letters and short sentences, the reading process is still fairly cumbersome. This study investigates the possibility of using an epiretinal prosthesis to stimulate visual braille as a sensory substitution for reading written letters and words. The Argus II retinal prosthesis system, used in this study, includes a 10 × 6 electrode array implanted epiretinally, a tiny video camera mounted on a pair of glasses, and a wearable computer that processes the video and determines the stimulation current of each electrode in real time. In the braille reading system, individual letters are created by a subset of dots from a 3 by 2 array of six dots. For the visual braille experiment, a grid of six electrodes was chosen out of the 10 × 6 Argus II array. Groups of these electrodes were then directly stimulated (bypassing the camera) to create visual percepts of individual braille letters. Experiments were performed in a single subject. Single letters were stimulated in an alternative forced choice (AFC) paradigm, and short 2–4-letter words were stimulated (one letter at a time) in an open-choice reading paradigm. The subject correctly identified 89% of single letters, 80% of 2-letter, 60% of 3-letter, and 70% of 4-letter words. This work suggests that text can successfully be stimulated and read as visual braille in retinal prosthesis patients. PMID:23189036
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Reading visual braille with a retinal prosthesis.
Lauritzen, Thomas Z; Harris, Jordan; Mohand-Said, Saddek; Sahel, Jose A; Dorn, Jessy D; McClure, Kelly; Greenberg, Robert J
2012-01-01
Retinal prostheses, which restore partial vision to patients blinded by outer retinal degeneration, are currently in clinical trial. The Argus II retinal prosthesis system was recently awarded CE approval for commercial use in Europe. While retinal prosthesis users have achieved remarkable visual improvement to the point of reading letters and short sentences, the reading process is still fairly cumbersome. This study investigates the possibility of using an epiretinal prosthesis to stimulate visual braille as a sensory substitution for reading written letters and words. The Argus II retinal prosthesis system, used in this study, includes a 10 × 6 electrode array implanted epiretinally, a tiny video camera mounted on a pair of glasses, and a wearable computer that processes the video and determines the stimulation current of each electrode in real time. In the braille reading system, individual letters are created by a subset of dots from a 3 by 2 array of six dots. For the visual braille experiment, a grid of six electrodes was chosen out of the 10 × 6 Argus II array. Groups of these electrodes were then directly stimulated (bypassing the camera) to create visual percepts of individual braille letters. Experiments were performed in a single subject. Single letters were stimulated in an alternative forced choice (AFC) paradigm, and short 2-4-letter words were stimulated (one letter at a time) in an open-choice reading paradigm. The subject correctly identified 89% of single letters, 80% of 2-letter, 60% of 3-letter, and 70% of 4-letter words. This work suggests that text can successfully be stimulated and read as visual braille in retinal prosthesis patients.
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Tracking Holland Interest Codes: The Case of South African Field Guides
ERIC Educational Resources Information Center
Watson, Mark B.; Foxcroft, Cheryl D.; Allen, Lynda J.
2007-01-01
Holland believes that specific personality types seek out matching occupational environments and his theory codes personality and environment according to a six letter interest typology. Since 1985 there have been numerous American studies that have queried the validity of Holland's coding system. Research in South Africa is scarcer, despite…
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Computer-Based Learning of Spelling Skills in Children with and without Dyslexia
ERIC Educational Resources Information Center
Kast, Monika; Baschera, Gian-Marco; Gross, Markus; Jancke, Lutz; Meyer, Martin
2011-01-01
Our spelling training software recodes words into multisensory representations comprising visual and auditory codes. These codes represent information about letters and syllables of a word. An enhanced version, developed for this study, contains an additional phonological code and an improved word selection controller relying on a phoneme-based…
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Development of early handwriting: Visual-motor control during letter copying.
Maldarelli, Jennifer E; Kahrs, Björn A; Hunt, Sarah C; Lockman, Jeffrey J
2015-07-01
Despite the importance of handwriting for school readiness and early academic progress, prior research on the development of handwriting has focused primarily on the product rather than the process by which young children write letters. In contrast, in the present work, early handwriting is viewed as involving a suite of perceptual, motor, and cognitive abilities, which must work in unison if children are to write letters efficiently. To study such coordination, head-mounted eye-tracking technology was used to investigate the process of visual-motor coordination while kindergarten children (N = 23) and adults (N = 11) copied individual letters and strings of letters that differed in terms of their phonemic properties. Results indicated that kindergarten children were able to copy single letters efficiently, as did adults. When the cognitive demands of the task increased and children were presented with strings of letters, however, their ability to copy letters efficiently was compromised: Children frequently interrupted their writing midletter, whereas they did not do so on single letter trials. Yet, with increasing age, children became more efficient in copying letter strings, in part by using vision more prospectively when writing. Taken together, the results illustrate how the coordination of perceptual, motor, and cognitive processes contributes to advances in the development of letter writing skill. (c) 2015 APA, all rights reserved).
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76 FR 4395 - Postal Service Price Adjustment
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-25
... the First-Class Mail, single- piece first-ounce letter price; however, the additional-ounce rate for single-piece letters and flats increases from 17 cents to 20 cents. Id. at 12. The price of a single-piece postcard increases from 28 cents to 29 cents. Id. However, to meet the cap average increase for...
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Preliminary Classification of Army and Navy Entry-Level Occupations by the Holland Coding System.
1986-12-01
Dictionary of Holland Occupational Codes (DOHC; see Gottfredson , Holland, & Ogawa, 1982) either directly or through expert judgment. Results...publications: The Dictionary of Holland Occupational Codes (DHOC; Gottfredson , Holland, & Ogawa, 192) and The Occupations Finder (Holland, 1978). The...occupational categories ( Gottfredson et al., 1982). The agreement between the first letters codes obtained from the 1977 Occupations Finder and the
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There is no clam with coats in the calm coast: delimiting the transposed-letter priming effect.
Duñabeitia, Jon Andoni; Perea, Manuel; Carreiras, Manuel
2009-10-01
In this article, we explore the transposed-letter priming effect (e.g., jugde-JUDGE vs. jupte-JUDGE), a phenomenon that taps into some key issues on how the brain encodes letter positions and has favoured the creation of new input coding schemes. However, almost all the empirical evidence from transposed-letter priming experiments comes from nonword primes (e.g., jugde-JUDGE). Indeed, previous evidence when using word-word pairs (e.g., causal-CASUAL) is not conclusive. Here, we conducted five masked priming lexical decision experiments that examined the relationship between pairs of real words that differed only in the transposition of two of their letters (e.g., CASUAL vs. CAUSAL). Results showed that, unlike transposed-letter nonwords, transposed-letter words do not seem to affect the identification time of their transposed-letter mates. Thus, prime lexicality is a key factor that modulates the magnitude of transposed-letter priming effects. These results are interpreted under the assumption of the existence of lateral inhibition processes occurring within the lexical level-which cancels out any orthographic facilitation due to the overlapping letters. We examine the implications of these findings for models of visual-word recognition.
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Transposed Letter Priming with Horizontal and Vertical Text in Japanese and English Readers
ERIC Educational Resources Information Center
Witzel, Naoko; Qiao, Xiaomei; Forster, Kenneth
2011-01-01
It is well established that in masked priming, a target word (e.g., "JUDGE") is primed more effectively by a transposed letter (TL) prime (e.g., "jugde") than by an orthographic control prime (e.g., "junpe"). This is inconsistent with the slot coding schemes used in many models of visual word recognition. Several…
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-17
... 70857 (Nov. 27, 2012). \\7\\ See Letter from Stephen Matthews, Senior Associate General Counsel, NASDAQ.... 13, 2013. See Letter from Jeffrey S. Davis, Vice President and Deputy General Counsel, NASDAQ OMX.... O'Neill, Deputy Secretary . [FR Doc. 2013-08974 Filed 4-16-13; 8:45 am] BILLING CODE 8011-01-P ...
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Predictors of Sensitivity to Perceptual Learning in Children With Infantile Nystagmus.
Huurneman, Bianca; Boonstra, F Nienke; Goossens, Jeroen
2017-08-01
To identify predictors of sensitivity to perceptual learning on a computerized, near-threshold letter discrimination task in children with infantile nystagmus (idiopathic IN: n = 18; oculocutaneous albinism accompanied by IN: n = 18). Children were divided into two age-, acuity-, and diagnosis-matched training groups: a crowded (n = 18) and an uncrowded training group (n = 18). Training consisted of 10 sessions spread out over 5 weeks (grand total of 3500 trials). Baseline performance, age, diagnosis, training condition, and perceived pleasantness of training (training joy) were entered as linear regression predictors of training-induced changes on a single- and a crowded-letter task. An impressive 57% of the variability in improvements of single-letter visual acuity was explained by age, training condition, and training joy. Being older and training with uncrowded letters were associated with larger single-letter visual acuity improvements. More training joy was associated with a larger gain from the uncrowded training and a smaller gain from the crowded training. Fifty-six percent of the variability in crowded-letter task improvements was explained by baseline performance, age, diagnosis, and training condition. After regressing out the variability induced by training condition, baseline performance, and age, perceptual learning proved more effective for children with idiopathic IN than for children with albinism accompanied by IN. Training gains increased with poorer baseline performance in idiopaths, but not in children with albinism accompanied by IN. Age and baseline performance, but not training joy, are important prognostic factors for the effect of perceptual learning in children with IN. However, their predictive value for achieving improvements in single-letter acuity and crowded letter acuity, respectively, differs between diagnostic subgroups and training condition. These findings may help with personalized treatment of individuals likely to benefit from perceptual learning.
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Transposed-letter priming effects in reading aloud words and nonwords.
Mousikou, Petroula; Kinoshita, Sachiko; Wu, Simon; Norris, Dennis
2015-10-01
A masked nonword prime generated by transposing adjacent inner letters in a word (e.g., jugde) facilitates the recognition of the target word (JUDGE) more than a prime in which the relevant letters are replaced by different letters (e.g., junpe). This transposed-letter (TL) priming effect has been widely interpreted as evidence that the coding of letter position is flexible, rather than precise. Although the TL priming effect has been extensively investigated in the domain of visual word recognition using the lexical decision task, very few studies have investigated this empirical phenomenon in reading aloud. In the present study, we investigated TL priming effects in reading aloud words and nonwords and found that these effects are of equal magnitude for the two types of items. We take this result as support for the view that the TL priming effect arises from noisy perception of letter order within the prime prior to the mapping of orthography to phonology.
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Code-Switching in Judaeo-Arabic Documents from the Cairo Geniza
ERIC Educational Resources Information Center
Wagner, Esther-Miriam; Connolly, Magdalen
2018-01-01
This paper investigates code-switching and script-switching in medieval documents from the Cairo Geniza, written in Judaeo-Arabic (Arabic in Hebrew script), Hebrew, Arabic and Aramaic. Legal documents regularly show a macaronic style of Judaeo-Arabic, Aramaic and Hebrew, while in letters code-switching from Judaeo-Arabic to Hebrew is tied in with…
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Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 13 2013-01-01 2013-01-01 false Guide Letter to Delinquent FmHA or Its Successor Agency Under Public Law 103-354 Single Family Housing Loan Borrowers E Exhibit E to Subpart K of Part..., Subpt. K, Exh. E Exhibit E to Subpart K of Part 1944—Guide Letter to Delinquent FmHA or Its Successor...
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Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 13 2012-01-01 2012-01-01 false Guide Letter to Delinquent FmHA or Its Successor Agency Under Public Law 103-354 Single Family Housing Loan Borrowers E Exhibit E to Subpart K of Part..., Subpt. K, Exh. E Exhibit E to Subpart K of Part 1944—Guide Letter to Delinquent FmHA or Its Successor...
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Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 13 2014-01-01 2013-01-01 true Guide Letter to Delinquent FmHA or Its Successor Agency Under Public Law 103-354 Single Family Housing Loan Borrowers E Exhibit E to Subpart K of Part..., Subpt. K, Exh. E Exhibit E to Subpart K of Part 1944—Guide Letter to Delinquent FmHA or Its Successor...
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Schubert, Teresa; Badcock, Nicholas; Kohnen, Saskia
2017-10-01
Letter recognition and digit recognition are critical skills for literate adults, yet few studies have considered the development of these skills in children. We conducted a nine-alternative forced-choice (9AFC) partial report task with strings of letters and digits, with typographical symbols (e.g., $, @) as a control, to investigate the development of identity and position processing in children. This task allows for the delineation of identity processing (as overall accuracy) and position coding (as the proportion of position errors). Our participants were students in Grade 1 to Grade 6, allowing us to track the development of these abilities across the primary school years. Our data suggest that although digit processing and letter processing end up with many similarities in adult readers, the developmental trajectories for identity and position processing for the two character types differ. Symbol processing showed little developmental change in terms of identity or position accuracy. We discuss the implications of our results for theories of identity and position coding: modified receptive field, multiple-route model, and lexical tuning. Despite moderate success for some theories, considerable theoretical work is required to explain the developmental trajectories of letter processing and digit processing, which might not be as closely tied in child readers as they are in adult readers. Copyright © 2017 Elsevier Inc. All rights reserved.
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Perceptual uncertainty is a property of the cognitive system.
Perea, Manuel; Carreiras, Manuel
2012-10-01
We qualify Frost's proposals regarding letter-position coding in visual word recognition and the universal model of reading. First, we show that perceptual uncertainty regarding letter position is not tied to European languages-instead it is a general property of the cognitive system. Second, we argue that a universal model of reading should incorporate a developmental view of the reading process.
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Error-Transparent Quantum Gates for Small Logical Qubit Architectures
NASA Astrophysics Data System (ADS)
Kapit, Eliot
2018-02-01
One of the largest obstacles to building a quantum computer is gate error, where the physical evolution of the state of a qubit or group of qubits during a gate operation does not match the intended unitary transformation. Gate error stems from a combination of control errors and random single qubit errors from interaction with the environment. While great strides have been made in mitigating control errors, intrinsic qubit error remains a serious problem that limits gate fidelity in modern qubit architectures. Simultaneously, recent developments of small error-corrected logical qubit devices promise significant increases in logical state lifetime, but translating those improvements into increases in gate fidelity is a complex challenge. In this Letter, we construct protocols for gates on and between small logical qubit devices which inherit the parent device's tolerance to single qubit errors which occur at any time before or during the gate. We consider two such devices, a passive implementation of the three-qubit bit flip code, and the author's own [E. Kapit, Phys. Rev. Lett. 116, 150501 (2016), 10.1103/PhysRevLett.116.150501] very small logical qubit (VSLQ) design, and propose error-tolerant gate sets for both. The effective logical gate error rate in these models displays superlinear error reduction with linear increases in single qubit lifetime, proving that passive error correction is capable of increasing gate fidelity. Using a standard phenomenological noise model for superconducting qubits, we demonstrate a realistic, universal one- and two-qubit gate set for the VSLQ, with error rates an order of magnitude lower than those for same-duration operations on single qubits or pairs of qubits. These developments further suggest that incorporating small logical qubits into a measurement based code could substantially improve code performance.
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Data Bank 5 - Origin and Destination Survey City/Airport Nomenclature : fourth quarter : [2006-01
DOT National Transportation Integrated Search
2006-01-01
This CD presents the letter alphabetic codes, numeric codes, full name spelling (up to 30 characters), abbreviated name spelling (up to 20 characters), and geographic coordinates for all cities in flight itineraries reported in the Passenger Origin a...
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Prosody and Intonation of Western Cham
ERIC Educational Resources Information Center
Ueki, Kaori
2011-01-01
This dissertation investigates the prosodic and intonational characteristics of Western Cham (three letter code for International Organization for Standardization's ISO 639-3 code: [iso=cja]), an Austronesian language in the Chamic sub-group. I examine acoustic variables of prominence at word and postlexical levels: syllable duration, pitch…
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Military Professional Ethics, Code of Conduct, and Military Academies’ Honor Codes,
1985-04-01
1981. Mathews, Jay. Ex-POW teaches that a mind can always be free. Washington Post 1:1+, 10 January 1983. 16 Meade, Henry J. Commitment to integrity. Air...to honor code’s review. Air Force Times 45:7, 4 February 1985. Glab , John E. Honor at West Point. (Letter) New York Times 26:5, 13 September 1976
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From Grapheme to Phonological Output: Performance of Adults Who Stutter on a Word Jumble Task
McGill, Megann; Sussman, Harvey; Byrd, Courtney T.
2016-01-01
Purpose The purpose of the present study was to extend previous research by analyzing the ability of adults who stutter to use phonological working memory in conjunction with lexical access to perform a word jumble task. Method Forty English words consisting of 3-, 4-, 5-, and 6-letters (n = 10 per letter length category) were randomly jumbled using a web-based application. During the experimental task, 26 participants were asked to silently manipulate the scrambled letters to form a real word. Each vocal response was coded for accuracy and speech reaction time (SRT). Results Adults who stutter attempted to solve fewer word jumble stimuli than adults who do not stutter at the 4-letter, 5-letter, and 6-letter lengths. Additionally, adults who stutter were significantly less accurate solving word jumble tasks at the 4-letter, 5-letter, and 6-letter lengths compared to adults who do not stutter. At the longest word length (6-letter), SRT was significantly slower for the adults who stutter than the fluent controls. Conclusion Results of the current study lend further support to the notion that differences in various aspects of phonological processing, including vision-to-sound conversions, sub-vocal stimulus manipulation, and/or lexical access are compromised in adults who stutter. PMID:26963917
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39 CFR Appendix A to Subpart A of... - Mail Classification Schedule
Code of Federal Regulations, 2012 CFR
2012-07-01
... Density and Saturation Letters High Density and Saturation Flats/Parcels Carrier Route Letters Flats Not... Package Services Single-Piece Parcel Post Inbound Surface Parcel Post (at UPU rates) Bound Printed Matter... Single-Piece First-Class Mail International Standard Mail (Regular and Nonprofit) High Density and...
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14 CFR Appendix B to Part 63 - Flight Navigator Training Course Requirements
Code of Federal Regulations, 2010 CFR
2010-01-01
... include additional subjects in the ground training curriculum, such as international law, flight hygiene... weather reports. Forecasting. International Morse code: Ability to receive code groups of letters and... school subjects. (3) Each instructor who conducts flight training must hold a valid flight navigator...
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The role of visual spatial attention in adult developmental dyslexia.
Collis, Nathan L; Kohnen, Saskia; Kinoshita, Sachiko
2013-01-01
The present study investigated the nature of visual spatial attention deficits in adults with developmental dyslexia, using a partial report task with five-letter, digit, and symbol strings. Participants responded by a manual key press to one of nine alternatives, which included other characters in the string, allowing an assessment of position errors as well as intrusion errors. The results showed that the dyslexic adults performed significantly worse than age-matched controls with letter and digit strings but not with symbol strings. Both groups produced W-shaped serial position functions with letter and digit strings. The dyslexics' deficits with letter string stimuli were limited to position errors, specifically at the string-interior positions 2 and 4. These errors correlated with letter transposition reading errors (e.g., reading slat as "salt"), but not with the Rapid Automatized Naming (RAN) task. Overall, these results suggest that the dyslexic adults have a visual spatial attention deficit; however, the deficit does not reflect a reduced span in visual-spatial attention, but a deficit in processing a string of letters in parallel, probably due to difficulty in the coding of letter position.
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Quantum and Private Capacities of Low-Noise Channels
NASA Astrophysics Data System (ADS)
Leditzky, Felix; Leung, Debbie; Smith, Graeme
2018-04-01
We determine both the quantum and the private capacities of low-noise quantum channels to leading orders in the channel's distance to the perfect channel. It has been an open problem for more than 20 yr to determine the capacities of some of these low-noise channels such as the depolarizing channel. We also show that both capacities are equal to the single-letter coherent information of the channel, again to leading orders. We thus find that, in the low-noise regime, superadditivity and degenerate codes have a negligible benefit for the quantum capacity, and shielding does not improve the private capacity beyond the quantum capacity, in stark contrast to the situation when noisier channels are considered.
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Thurlow, W R
1980-01-01
Experiments with keyboard arrangements of letters show that simple alphabetic letter-key sequences with 4 to 5 letters in a row lead to most rapid visual search performance. Such arrangements can be used on keyboards operated by the index finger of one hand. Arrangement of letters in words offers a promising alternative because these arrangements can be readily memorized and can result in small interletter distances on the keyboard for frequently occurring letter sequences. Experiments on operation of keyboards show that a space or shift key operated by the left hand (which also holds the communication device) results in faster keyboard operation than when space or shift keys on the front of the keyboard (operated by right hand) are used. Special problems of the deaf-blind are discussed. Keyboard arrangements are investigated, and matching tactual codes are suggested.
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Selected DOE headquarters publications
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1979-04-01
This publication provides listings of (mainly policy and programmatic) publications which have been issued by headquarters organizations of the Department of Energy; assigned a DOE/XXX- type report number code, where XXX is the 1- to 4-letter code for the issuing headquarters organization; received by the Energy Library; and made available to the public.
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Bulimia nervosa: friend or foe? The pros and cons of bulimia nervosa.
Serpell, Lucy; Treasure, Janet
2002-09-01
The aim of the current study was to use a qualitative approach to investigate the attitude of people with bulimia nervosa (BN) to their illness. Patients with BN were asked to write two letters to their bulimia, one addressing it as a friend and the other addressing it as an enemy. We used a coding scheme to classify themes in letters of people with anorexia nervosa (AN) to group together themes expressed by those with BN. We revised the coding scheme to include themes that were not present in the letters of people with AN. There were both similarities and differences in the themes described by AN and BN patients. Two positive themes (BN allowing the individuals to eat and not get fat and BN as a way of dealing with boredom) and two negative themes (shame or low self-esteem resulting from BN and obsessive thoughts of weight and shape) were added to the coding scheme to account for these differences. The positive and negative aspects of BN differ in some important ways from those expressed by patients with AN. The meaning of these differences is discussed with reference to the wider symptom pattern of BN compared with AN and their importance with reference to motivation for change is outlined. Copyright 2002 by Wiley Periodicals, Inc.
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Chazard, Emmanuel; Mouret, Capucine; Ficheur, Grégoire; Schaffar, Aurélien; Beuscart, Jean-Baptiste; Beuscart, Régis
2014-04-01
Medical free-text records enable to get rich information about the patients, but often need to be de-identified by removing the Protected Health Information (PHI), each time the identification of the patient is not mandatory. Pattern matching techniques require pre-defined dictionaries, and machine learning techniques require an extensive training set. Methods exist in French, but either bring weak results or are not freely available. The objective is to define and evaluate FASDIM, a Fast And Simple De-Identification Method for French medical free-text records. FASDIM consists in removing all the words that are not present in the authorized word list, and in removing all the numbers except those that match a list of protection patterns. The corresponding lists are incremented in the course of the iterations of the method. For the evaluation, the workload is estimated in the course of records de-identification. The efficiency of the de-identification is assessed by independent medical experts on 508 discharge letters that are randomly selected and de-identified by FASDIM. Finally, the letters are encoded after and before de-identification according to 3 terminologies (ATC, ICD10, CCAM) and the codes are compared. The construction of the list of authorized words is progressive: 12h for the first 7000 letters, 16 additional hours for 20,000 additional letters. The Recall (proportion of removed Protected Health Information, PHI) is 98.1%, the Precision (proportion of PHI within the removed token) is 79.6% and the F-measure (harmonic mean) is 87.9%. In average 30.6 terminology codes are encoded per letter, and 99.02% of those codes are preserved despite the de-identification. FASDIM gets good results in French and is freely available. It is easy to implement and does not require any predefined dictionary. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.
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Symbol processing in the left angular gyrus: evidence from passive perception of digits.
Price, Gavin R; Ansari, Daniel
2011-08-01
Arabic digits are one of the most ubiquitous symbol sets in the world. While there have been many investigations into the neural processing of the semantic information digits represent (e.g. through numerical comparison tasks), little is known about the neural mechanisms which support the processing of digits as visual symbols. To characterise the component neurocognitive mechanisms which underlie numerical cognition, it is essential to understand the processing of digits as a visual category, independent of numerical magnitude processing. The 'Triple Code Model' (Dehaene, 1992; Dehaene and Cohen, 1995) posits an asemantic visual code for processing Arabic digits in the ventral visual stream, yet there is currently little empirical evidence in support of this code. This outstanding question was addressed in the current functional Magnetic Resonance (fMRI) study by contrasting brain responses during the passive viewing of digits versus letters and novel symbols at short (50 ms) and long (500 ms) presentation times. The results of this study reveal increased activation for familiar symbols (digits and letters) relative to unfamiliar symbols (scrambled digits and letters) at long presentation durations in the left dorsal Angular gyrus (dAG). Furthermore, increased activation for Arabic digits was observed in the left ventral Angular gyrus (vAG) in comparison to letters, scrambled digits and scrambled letters at long presentation durations, but no digit specific activation in any region at short presentation durations. These results suggest an absence of a digit specific 'Visual Number Form Area' (VNFA) in the ventral visual cortex, and provide evidence for the role of the left ventral AG during the processing of digits in the absence of any explicit processing demands. We conclude that Arabic digit processing depends specifically on the left AG rather than a ventral visual stream VNFA. Copyright © 2011 Elsevier Inc. All rights reserved.
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Accurate Reading with Sequential Presentation of Single Letters
Price, Nicholas S. C.; Edwards, Gemma L.
2012-01-01
Rapid, accurate reading is possible when isolated, single words from a sentence are sequentially presented at a fixed spatial location. We investigated if reading of words and sentences is possible when single letters are rapidly presented at the fovea under user-controlled or automatically controlled rates. When tested with complete sentences, trained participants achieved reading rates of over 60 wpm and accuracies of over 90% with the single letter reading (SLR) method and naive participants achieved average reading rates over 30 wpm with greater than 90% accuracy. Accuracy declined as individual letters were presented for shorter periods of time, even when the overall reading rate was maintained by increasing the duration of spaces between words. Words in the lexicon that occur more frequently were identified with higher accuracy and more quickly, demonstrating that trained participants have lexical access. In combination, our data strongly suggest that comprehension is possible and that SLR is a practicable form of reading under conditions in which normal scanning of text is not possible, or for scenarios with limited spatial and temporal resolution such as patients with low vision or prostheses. PMID:23115548
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Basic Reading Instruction for Students in Automotive Occupations. Student's Handbook.
ERIC Educational Resources Information Center
General Behavioral Systems, Inc., Torrance, CA.
The basic reading course outlined in this student handbook emphasizes the decoding process. The contents consist of a letter-and-sound spelling chart and 87 course modules which are based on single-letter and letter-combination sounds. Many of the modules include exercises, and some contain reading material. (JM)
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Is the Orthographic/Phonological Onset a Single Unit in Reading Aloud?
ERIC Educational Resources Information Center
Mousikou, Petroula; Coltheart, Max; Saunders, Steven; Yen, Lisa
2010-01-01
Two main theories of visual word recognition have been developed regarding the way orthographic units in printed words map onto phonological units in spoken words. One theory suggests that a string of single letters or letter clusters corresponds to a string of phonemes (Coltheart, 1978; Venezky, 1970), while the other suggests that a string of…
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ERIC Educational Resources Information Center
Petersen, Anders; Andersen, Tobias S.
2012-01-01
The psychometric function of single-letter identification is typically described as a function of stimulus intensity. However, the effect of stimulus exposure duration on letter identification remains poorly described. This is surprising because the effect of exposure duration has played a central role in modeling performance in whole and partial…
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Lee, Joseph G. L.; Ranney, Leah M.; Goldstein, Adam O.
2016-01-01
Importance: Single cigarettes, which are sold without warning labels and often evade taxes, can serve as a gateway for youth smoking. The Family Smoking Prevention and Tobacco Control Act of 2009 gives the US Food and Drug Administration (FDA) authority to regulate the manufacture, distribution, and marketing of tobacco products, including prohibiting the sale of single cigarettes. To enforce these regulations, the FDA conducted over 335 661 inspections between 2010 and September 30, 2014, and allocated over $115 million toward state inspections contracts. Objective: To examine differences in single cigarette violations across states and determine if likely correlates of single cigarette sales predict single cigarette violations at the state level. Design: Cross-sectional study of publicly available FDA warning letters from January 1 to July 31, 2014. Setting: All 50 states and the District of Columbia. Participants: Tobacco retailer inspections conducted by FDA (n = 33 543). Exposure(s) for Observational Studies: State cigarette tax, youth smoking prevalence, poverty, and tobacco production. Main Outcome(s) and Measure(s): State proportion of FDA warning letters issued for single cigarette violations. Results: There are striking differences in the number of single cigarette violations found by state, with 38 states producing no warning letters for selling single cigarettes even as state policymakers developed legislation to address retailer sales of single cigarettes. The state proportion of warning letters issued for single cigarettes is not predicted by state cigarette tax, youth smoking, poverty, or tobacco production, P = .12. Conclusions and Relevance: Substantial, unexplained variation exists in violations of single cigarette sales among states. These data suggest the possibility of differences in implementation of FDA inspections and the need for stronger quality monitoring processes across states implementing FDA inspections. PMID:25744967
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Baker, Hannah M; Lee, Joseph G L; Ranney, Leah M; Goldstein, Adam O
2016-02-01
Single cigarettes, which are sold without warning labels and often evade taxes, can serve as a gateway for youth smoking. The Family Smoking Prevention and Tobacco Control Act of 2009 gives the US Food and Drug Administration (FDA) authority to regulate the manufacture, distribution, and marketing of tobacco products, including prohibiting the sale of single cigarettes. To enforce these regulations, the FDA conducted over 335,661 inspections between 2010 and September 30, 2014, and allocated over $115 million toward state inspections contracts. To examine differences in single cigarette violations across states and determine if likely correlates of single cigarette sales predict single cigarette violations at the state level. Cross-sectional study of publicly available FDA warning letters from January 1 to July 31, 2014. All 50 states and the District of Columbia. Tobacco retailer inspections conducted by FDA (n = 33 543). State cigarette tax, youth smoking prevalence, poverty, and tobacco production. State proportion of FDA warning letters issued for single cigarette violations. There are striking differences in the number of single cigarette violations found by state, with 38 states producing no warning letters for selling single cigarettes even as state policymakers developed legislation to address retailer sales of single cigarettes. The state proportion of warning letters issued for single cigarettes is not predicted by state cigarette tax, youth smoking, poverty, or tobacco production, P = .12. Substantial, unexplained variation exists in violations of single cigarette sales among states. These data suggest the possibility of differences in implementation of FDA inspections and the need for stronger quality monitoring processes across states implementing FDA inspections. © The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
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Automaticity in reading and the Stroop task: testing the limits of involuntary word processing.
Brown, Tracy L; Joneleit, Kelly; Robinson, Cathy S; Brown, Carli Rose
2002-01-01
We investigated the parameters of involuntary word reading in the Stroop task in 7 experiments. Experiments 1-4 varied response modality and the presence of congruent word trials in a test of the claim that presenting a Stroop color word with only one letter in the target color eliminates the Stroop effect. Experiments 5 and 6 addressed the roles of spatial attention and orthographic processing as possible mechanisms behind the reduction of Stroop effects with the single-letter format. Experiment 7 investigated the limits of involuntary reading under optimal conditions for selective processing of rectangular color patch targets. We found that the single-letter format reduced but never eliminated Stroop effects, spatial attention but not orthographic processing plays a role in the effect of the single-letter format, and word reading is not completely prevented even with austere presentation conditions. We conclude with a defense of the involuntariness criterion for automaticity in the Stroop task, particularly when word reading is viewed in the context of a skilled performance.
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Brault Foisy, Lorie-Marlène; Ahr, Emmanuel; Masson, Steve; Houdé, Olivier; Borst, Grégoire
2017-10-01
Children tend to confuse reversible letters such as b and d when they start learning to read. According to some authors, mirror errors are a consequence of the mirror generalization (MG) process that allows one to recognize objects independently of their left-right orientation. Although MG is advantageous for the visual recognition of objects, it is detrimental for the visual recognition of reversible letters. Previous studies comparing novice and expert readers demonstrated that MG must be inhibited to discriminate reversible single letters. In this study, we investigated whether MG must also be inhibited by novice readers to discriminate between two pseudowords containing reversible letters. Readable pseudowords, rather than words, were used to mimic early non-automatic stages of reading when reading is achieved by decoding words through grapheme-phoneme pairing and combination. We designed a negative priming paradigm in which school-aged children (10-year-olds) were asked to judge whether two pseudowords were identical on the prime and whether two animals were identical on the probe. Children required more time to determine that two animals were mirror images of each other when preceded by pseudowords containing the reversible letter b or d than when preceded by different pseudowords containing the control letter f or t (Experiment 1) or by different pseudowords that differed only by the target letter f or k (Experiment 2). These results suggest that MG must be inhibited to discriminate between pseudowords containing reversible letters, generalizing the findings regarding single letters to a context more representative of the early stages of reading. Copyright © 2017 Elsevier Inc. All rights reserved.
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1989-05-31
for the effects. Most of the pqychophysiological research has examined event-related potentials (ERPs). Bashore (Chapter 7 ), Ragot (Chapter 8), and...flanking noise letters I signaled a response that was incongruent with the resTcnse i:.dicated b., a target letter. Bashore (Chapter 7 ) describes a...forms. First, compatibility effects have been used as estimates of interhemispheric transmission time (Bashore, I Chapter 7 ). The logic, articulated
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Word and Pseudoword Superiority Effects: Evidence From a Shallow Orthography Language.
Ripamonti, Enrico; Luzzatti, Claudio; Zoccolotti, Pierluigi; Traficante, Daniela
2017-08-03
The Word Superiority Effect (WSE) denotes better recognition of a letter embedded in a word rather than in a pseudoword. Along with WSE, also a Pseudoword Superiority Effect (PSE) has been described: it is easier to recognize a letter in a legal pseudoword than in an unpronounceable nonword. At the current state of the art, both WSE and PSE have been mainly tested with English speakers. The present study uses the Reicher-Wheeler paradigm with native speakers of Italian (a shallow orthography language). Differently from English and French, we found WSE for RTs only, whereas PSE was significant for both accuracy and reaction times (RTs). This finding indicates that, in the Reicher-Wheeler task, readers of a shallow orthography language can effectively rely on both the lexical and the sublexical routes. As to the effect of letter position, a clear advantage for the first letter position emerged, a finding suggesting a fine-grained processing of the letter strings with coding of letter position, and indicating the role of visual acuity and crowding factors.
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The locus of impairment in English developmental letter position dyslexia
Kezilas, Yvette; Kohnen, Saskia; McKague, Meredith; Castles, Anne
2014-01-01
Many children with reading difficulties display phonological deficits and struggle to acquire non-lexical reading skills. However, not all children with reading difficulties have these problems, such as children with selective letter position dyslexia (LPD), who make excessive migration errors (such as reading slime as “smile”). Previous research has explored three possible loci for the deficit – the phonological output buffer, the orthographic input lexicon, and the orthographic-visual analysis stage of reading. While there is compelling evidence against a phonological output buffer and orthographic input lexicon deficit account of English LPD, the evidence in support of an orthographic-visual analysis deficit is currently limited. In this multiple single-case study with three English-speaking children with developmental LPD, we aimed to both replicate and extend previous findings regarding the locus of impairment in English LPD. First, we ruled out a phonological output buffer and an orthographic input lexicon deficit by administering tasks that directly assess phonological processing and lexical guessing. We then went on to directly assess whether or not children with LPD have an orthographic-visual analysis deficit by modifying two tasks that have previously been used to localize processing at this level: a same-different decision task and a non-word reading task. The results from these tasks indicate that LPD is most likely caused by a deficit specific to the coding of letter positions at the orthographic-visual analysis stage of reading. These findings provide further evidence for the heterogeneity of dyslexia and its underlying causes. PMID:24917802
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A new brain-computer interface design using fuzzy ARTMAP.
Palaniappan, Ramaswamy; Paramesran, Raveendran; Nishida, Shogo; Saiwaki, Naoki
2002-09-01
This paper proposes a new brain-computer interface (BCI) design using fuzzy ARTMAP (FA) neural network, as well as an application of the design. The objective of this BCI-FA design is to classify the best three of the five available mental tasks for each subject using power spectral density (PSD) values of electroencephalogram (EEG) signals. These PSD values are extracted using the Wiener-Khinchine and autoregressive methods. Ten experiments employing different triplets of mental tasks are studied for each subject. The findings show that the average BCI-FA outputs for four subjects gave less than 6% of error using the best triplets of mental tasks identified from the classification performances of FA. This implies that the BCI-FA can be successfully used with a tri-state switching device. As an application, a proposed tri-state Morse code scheme could be utilized to translate the outputs of this BCI-FA design into English letters. In this scheme, the three BCI-FA outputs correspond to a dot and a dash, which are the two basic Morse code alphabets and a space to denote the end (or beginning) of a dot or a dash. The construction of English letters using this tri-state Morse code scheme is determined only by the sequence of mental tasks and is independent of the time duration of each mental task. This is especially useful for constructing letters that are represented as multiple dots or dashes. This combination of BCI-FA design and the tri-state Morse code scheme could be developed as a communication system for paralyzed patients.
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Kezilas, Yvette; McKague, Meredith; Kohnen, Saskia; Badcock, Nicholas A; Castles, Anne
2017-02-01
Masked transposed-letter (TL) priming effects have been used to index letter position processing over the course of reading development. Whereas some studies have reported an increase in TL priming over development, others have reported a decrease. These findings have led to the development of 2 somewhat contradictory accounts of letter position development: the lexical tuning hypothesis and the multiple-route model. One factor that may be contributing to these discrepancies is the use of baseline primes that substitute letters in the target word, which may confound the effect of changes in letter position processing over development with those of letter identity. The present study included an identity prime (e.g., listen-LISTEN), in addition to the standard two-substituted-letter (2SL; e.g., lidfen-LISTEN) and all-letter-different (ALD; e.g., rodfup-LISTEN) baselines, to remove the potential confound between letter position and letter identity information in determining the effect of the TL prime. Priming effects were measured in a lexical decision task administered to children aged 7-12 and a group of university students. Using inverse transformed response times, targets preceded by a TL prime were responded to significantly faster than those preceded by 2SL and ALD primes, and priming remained stable across development. In contrast, targets preceded by a TL prime were responded to significantly slower than those preceded by an ID prime, and this reaction-time cost increased significantly over development, with adults showing the largest cost. These findings are consistent with a lexical tuning account of letter position development, and are inconsistent with the multiple-route model. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
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Illusory conjunctions in simultanagnosia: coarse coding of visual feature location?
McCrea, Simon M; Buxbaum, Laurel J; Coslett, H Branch
2006-01-01
Simultanagnosia is a disorder characterized by an inability to see more than one object at a time. We report a simultanagnosic patient (ED) with bilateral posterior infarctions who produced frequent illusory conjunctions on tasks involving form and surface features (e.g., a red T) and form alone. ED also produced "blend" errors in which features of one familiar perceptual unit appeared to migrate to another familiar perceptual unit (e.g., "RO" read as "PQ"). ED often misread scrambled letter strings as a familiar word (e.g., "hmoe" read as "home"). Finally, ED's success in reporting two letters in an array was inversely related to the distance between the letters. These findings are consistent with the hypothesis that ED's illusory reflect coarse coding of visual feature location that is ameliorated in part by top-down information from object and word recognition systems; the findings are also consistent, however, with Treisman's Feature Integration Theory. Finally, the data provide additional support for the claim that the dorsal parieto-occipital cortex is implicated in the binding of visual feature information.
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Visual-Attentional Span and Lexical Decision in Skilled Adult Readers
ERIC Educational Resources Information Center
Holmes, Virginia M.; Dawson, Georgia
2014-01-01
The goal of the study was to examine the association between visual-attentional span and lexical decision in skilled adult readers. In the span tasks, an array of letters was presented briefly and recognition or production of a single cued letter (partial span) or production of all letters (whole span) was required. Independently of letter…
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Attentional blink in children with attention deficit hyperactivity disorder.
Amador-Campos, Juan A; Aznar-Casanova, J Antonio; Bezerra, Izabela; Torro-Alves, Nelson; Sánchez, Manuel M
2015-01-01
To explore the temporal mechanism of attention in children with attention deficit hyperactivity disorder (ADHD) and controls using a rapid serial visual presentation (RSVP) task in which two letters (T1 and T2) were presented in close temporal proximity among distractors (attentional blink [AB]). Thirty children aged between 9 and 13 years (12 with ADHD combined type and 18 controls) took part in the study. Both groups performed two kinds of RSVP task. In the single task, participants simply had to identify a target letter (T1), whereas in the dual task, they had to identify a target letter (T1) and a probe letter (T2). The ADHD and control groups were equivalent in their single-task performance. However, in the dual-task condition, there were significant between-group differences in the rate of detection of the probe letter (T2) at lag + 1 and lag + 4. The ADHD group exhibited a larger overall AB compared with controls. Our findings provide support for a link between ADHD and attentional blink.
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Family Access to a Dentist Study (FADS): A Multi-Center Randomized Controlled Trial
Nelson, Suchitra; Riedy, Christine; Albert, Jeffrey M; Lee, Wonik; Slusar, Mary Beth; Curtan, Shelley; Ferretti, Gerald; Cunha-Cruz, Joana; Milgrom, Peter
2015-01-01
Introduction Many low-income parent/caregivers do not understand the importance of cavity-free primary (baby) teeth and the chronic nature of dental caries (tooth decay). As a consequence, dental preventive and treatment utilization is low even when children are screened in schools and referred for care. This study aims to test a referral letter and Dental Information Guide (DIG) designed using the Common-Sense Model of Self-Regulation (CSM) framework to improve caregivers’ illness perception of dental caries and increase utilization of care by children with restorative dental needs. Methods A multi-site randomized controlled trial with caregivers of Kindergarten to 4th grade children in urban Ohio and rural Washington State will compare five arms: (1) CSM referral letter alone; (2) CSM referral letter + DIG; (3) reduced CSM referral letter alone; (4) reduced CSM referral letter + DIG; (5) standard (control) referral. At baseline, children will be screened at school to determine restorative dental needs. If in need of treatment, caregivers will be randomized to study arms and an intervention packet will be sent home. The primary outcome will be dental care based on a change in oral health status by clinical examination 7 months post-screening (ICDAS sealant codes 1 and 2; restoration codes 3–8; extraction). Enrollment commenced summer 2015 with results in summer 2016. Conclusion This study uses the CSM framework to develop and test behavioral interventions to increase dental utilization among low-income caregivers. If effective this simple intervention has broad applicability in clinical and community-based settings. PMID:26500170
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Family Access to a Dentist Study (FADS): A multi-center randomized controlled trial.
Nelson, Suchitra; Riedy, Christine; Albert, Jeffrey M; Lee, Wonik; Slusar, Mary Beth; Curtan, Shelley; Ferretti, Gerald; Cunha-Cruz, Joana; Milgrom, Peter
2015-11-01
Many low-income parent/caregivers do not understand the importance of cavity-free primary (baby) teeth and the chronic nature of dental caries (tooth decay). As a consequence, dental preventive and treatment utilization is low even when children are screened in schools and referred for care. This study aims to test a referral letter and Dental Information Guide (DIG) designed using the Common-Sense Model of Self-Regulation (CSM) framework to improve caregivers' illness perception of dental caries and increase utilization of care by children with restorative dental needs. A multi-site randomized controlled trial with caregivers of Kindergarten to 4th grade children in urban Ohio and rural Washington State will compare five arms: (1) CSM referral letter alone; (2) CSM referral letter+DIG; (3) reduced CSM referral letter alone; (4) reduced CSM referral letter+DIG; and (5) standard (control) referral. At baseline, children will be screened at school to determine restorative dental needs. If in need of treatment, caregivers will be randomized to study arms and an intervention packet will be sent home. The primary outcome will be dental care based on a change in oral health status by clinical examination 7 months post-screening (ICDAS sealant codes 1 and 2; restoration codes 3-8; extraction). Enrollment commenced summer 2015 with results in summer 2016. This study uses the CSM framework to develop and test behavioral interventions to increase dental utilization among low-income caregivers. If effective this simple intervention has broad applicability in clinical and community-based settings. Copyright © 2015 Elsevier Inc. All rights reserved.
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Thompson, Robert; Tanimoto, Steven; Abbott, Robert; Nielsen, Kathleen; Lyman, Ruby Dawn; Geselowitz, Kira; Habermann, Katrien; Mickail, Terry; Raskind, Marshall; Peverly, Stephen; Nagy, William; Berninger, Virginia
2017-01-01
This study in programmatic research on technology-supported instruction first identified, through pretesting using evidence-based criteria, students with persisting specific learning disabilities (SLDs) in written language during middle childhood (grades 4-6) and early adolescence (grades 7-9). Participants then completed computerized writing instruction and posttesting. The 12 computer lessons varied output modes (letter production by stylus alternating with hunt and peck keyboarding versus by pencil with grooves alternating with touch typing on keyboard), input (read or heard source material), and task (notes or summaries). Posttesting and coded notes and summaries showed the effectiveness of computerized writing instruction on both writing tasks for multiple modes of language input and letter production output for improving letter production and related writing skills.
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Thompson, Robert; Tanimoto, Steven; Abbott, Robert; Nielsen, Kathleen; Lyman, Ruby Dawn; Geselowitz, Kira; Habermann, Katrien; Mickail, Terry; Raskind, Marshall; Peverly, Stephen; Nagy, William; Berninger, Virginia
2017-01-01
This study in programmatic research on technology-supported instruction first identified, through pretesting using evidence-based criteria, students with persisting specific learning disabilities (SLDs) in written language during middle childhood (grades 4-6) and early adolescence (grades 7-9). Participants then completed computerized writing instruction and posttesting. The 12 computer lessons varied output modes (letter production by stylus alternating with hunt and peck keyboarding versus by pencil with grooves alternating with touch typing on keyboard), input (read or heard source material), and task (notes or summaries). Posttesting and coded notes and summaries showed the effectiveness of computerized writing instruction on both writing tasks for multiple modes of language input and letter production output for improving letter production and related writing skills. PMID:27434553
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Bioterrorism-related Inhalational Anthrax in an Elderly Woman, Connecticut, 2001
Mead, Paul; Armstrong, Gregory L.; Painter, John; Kelley, Katherine A.; Hoffmaster, Alex R.; Mayo, Donald; Barden, Diane; Ridzon, Renee; Parashar, Umesh; Teshale, Eyasu Habtu; Williams, Jen; Noviello, Stephanie; Perz, Joseph F.; Mast, Eric E.; Swerdlow, David L.; Hadler, James L.
2003-01-01
On November 20, 2001, inhalational anthrax was confirmed in an elderly woman from rural Connecticut. To determine her exposure source, we conducted an extensive epidemiologic, environmental, and laboratory investigation. Molecular subtyping showed that her isolate was indistinguishable from isolates associated with intentionally contaminated letters. No samples from her home or community yielded Bacillus anthracis, and she received no first-class letters from facilities known to have processed intentionally contaminated letters. Environmental sampling in the regional Connecticut postal facility yielded B. anthracis spores from 4 (31%) of 13 sorting machines. One extensively contaminated machine primarily processes bulk mail. A second machine that does final sorting of bulk mail for her zip code yielded B. anthracis on the column of bins for her carrier route. The evidence suggests she was exposed through a cross-contaminated bulk mail letter. Such cross-contamination of letters and postal facilities has implications for managing the response to future B. anthracis–contaminated mailings. PMID:12781007
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Code of Federal Regulations, 2010 CFR
2010-10-01
... solids, discharged by gravity Under pressure of more than 10 kPa (1.45 psig) For liquids Rigid 11 21 31 Flexible 13 (2) Intermediate bulk container code letter designations are as follows: “A” means steel (all types and surface treatments). “B” means aluminum. “C” means natural wood. “D” means plywood. “F” means...
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Evidence-Based Reading and Writing Assessment for Dyslexia in Adolescents and Young Adults
Nielsen, Kathleen; Abbott, Robert; Griffin, Whitney; Lott, Joe; Raskind, Wendy; Berninger, Virginia W.
2016-01-01
The same working memory and reading and writing achievement phenotypes (behavioral markers of genetic variants) validated in prior research with younger children and older adults in a multi-generational family genetics study of dyslexia were used to study 81 adolescent and young adults (ages 16 to 25) from that study. Dyslexia is impaired word reading and spelling skills below the population mean and ability to use oral language to express thinking. These working memory predictor measures were given and used to predict reading and writing achievement: Coding (storing and processing) heard and spoken words (phonological coding), read and written words (orthographic coding), base words and affixes (morphological coding), and accumulating words over time (syntax coding); Cross-Code Integration (phonological loop for linking phonological name and orthographic letter codes and orthographic loop for linking orthographic letter codes and finger sequencing codes), and Supervisory Attention (focused and switching attention and self-monitoring during written word finding). Multiple regressions showed that most predictors explained individual difference in at least one reading or writing outcome, but which predictors explained unique variance beyond shared variance depended on outcome. ANOVAs confirmed that research-supported criteria for dyslexia validated for younger children and their parents could be used to diagnose which adolescents and young adults did (n=31) or did not (n=50) meet research criteria for dyslexia. Findings are discussed in reference to the heterogeneity of phenotypes (behavioral markers of genetic variables) and their application to assessment for accommodations and ongoing instruction for adolescents and young adults with dyslexia. PMID:26855554
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Electroencephalography: Subdural Multi-Electrode Brain Chip.
1995-12-01
showing a blind subject reading Braille letters that had been inserted into his visual cortex by stimulating appropriate sets of electrodes. The...subject in Dobelle’s experiment 50 had been blind for 10 years and was able to read Braille at 30 letters a minute using a 64 electrode array for...Evans, "’ Braille ’ Reading by a Blind Volunteer by Visual cortex Stimulation," Nature, 259: 111-112 (January 1976). A.K. Engel, et al. "Temporal Coding
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Effect of Assessment Task and Letter Writing Ability on Preschool Children's Spelling Performance
ERIC Educational Resources Information Center
Puranik, Cynthia; Apel, Kenn
2010-01-01
The purpose of this study was to examine whether spelling performance in preschool children varied as a function of the method of assessment and letter writing ability. The authors manipulated the motoric element and memory demands of the task by having children spell single words using letter tiles, orally, and by writing. The authors also…
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Bindman, Samantha W.; Hindman, Annemarie H.; Aram, Dorit; Morrison, Frederick J.
2013-01-01
Parental writing support was examined over time and in relation to children’s language and literacy skills. Seventy-seven parents and their preschoolers were videotaped writing an invitation together twice during one year. Parental writing support was coded at the level of the letter to document parents’ graphophonemic support (letter–sound correspondence), print support (letter formation), and demand for precision (expectation for correcting writing errors). Parents primarily relied on only a couple print (i.e., parent writing the letter alone) and graphophonemic (i.e., saying the word as a whole, dictating letters as children write) strategies. Graphophonemic and print support in preschool predicted children’s decoding skills, and graphophonemic support also predicted children’s future phonological awareness. Neither type of support predicted children’s vocabulary scores. Demand for precision occurred infrequently and was unrelated to children’s outcomes. Findings demonstrate the importance of parental writing support for augmenting children’s literacy skills. PMID:25045186
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Northwest range-plant symbols adapted to automatic data processing.
George A. Garrison; Jon M. Skovlin
1960-01-01
Many range technicians, agronomists, foresters, biologists, and botanists of various educational institutions and government agencies in the Northwest have been using a four-letter symbol list or code compiled 12 years ago from records of plants collected by the U.S. Forest Service in Oregon and Washington, This code has served well as a means of entering plant names...
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ERIC Educational Resources Information Center
Ishitani, Terry T.
2010-01-01
This study applied hierarchical linear modeling to investigate the effect of congruence on intrinsic and extrinsic aspects of job satisfaction. Particular focus was given to differences in job satisfaction by gender and by Holland's first-letter codes. The study sample included nationally represented 1462 female and 1280 male college graduates who…
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ERIC Educational Resources Information Center
Hounsell, D.; And Others
This guide for teachers to the tape indexing system (TANDEM) in use at the Modern Languages Department at Portsmouth Polytechnic focuses on tape classification, numbering, labeling, and shelving system procedures. The appendixes contain information on: (1) the classification system and related codes, (2) color and letter codes, (3) marking of tape…
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NASA Astrophysics Data System (ADS)
Ćwikiel, K.; Matlak, M.
2006-03-01
We comment the Letter 'A novel experimental method: electrochemical detection of phase transition in ferroelectric single crystals', Chem. Phys. Lett. 384 (2004) 262 by K. Gatner and R. Jakubas. We indicate that the method used in this Letter is not 'A novel method' but the application of the method described in Refs. [M. Matlak, M. Pietruszka, E. Rówiński, Phys. Rev. B 63 (2001) 52101; M. Matlak, M. Pietruszka, E. Rówiński, Phys. Stat. Sol. A 184 (2001) 335; W. Gaweł, E. Zaleska, Z. Sztuba, Met. Sci. Eng. A 324 (2002) 255], well known to Gatner, but not cited in the commented Letter. Additionally Gatner, cooperating with us, has used our TGS samples and published the results in the commented Letter without our knowledge and permission.
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Berninger, Virginia W; Abbott, Robert D; Jones, Janine; Wolf, Beverly J; Gould, Laura; Anderson-Youngstrom, Marci; Shimada, Shirley; Apel, Kenn
2006-01-01
The first findings from a 5-year, overlapping-cohorts longitudinal study of typical language development are reported for (a) the interrelationships among Language by Ear (listening), Mouth (speaking), Eye (reading), and Hand (writing) in Cohort 1 in 1st and 3rd grade and Cohort 2 in 3rd and 5th grade; (b) the interrelationships among three modes of Language by Hand (writing manuscript letters with pen and keyboard and cursive letters with pen) in each cohort in the same grade levels as (a); and (c) the ability of the 1st graders in Cohort 1 and the 3rd graders in Cohort 2 to apply fast mapping in learning to spell pseudowords. Results showed that individual differences in Listening Comprehension, Oral Expression, Reading Comprehension, and Written Expression are stable developmentally, but each functional language system is only moderately correlated with the others. Likewise, manuscript writing, cursive writing, and keyboarding are only moderately correlated, and each has a different set of unique neuropsychological predictors depending on outcome measure and grade level. Results support the use of the following neuropsychological measures in assessing handwriting modes: orthographic coding, rapid automatic naming, finger succession (grapho-motor planning for sequential finger movements), inhibition, inhibition/switching, and phonemes skills (which may facilitate transfer of abstract letter identities across letter formats and modes of production). Both 1st and 3rd graders showed evidence of fast mapping of novel spoken word forms onto written word forms over 3 brief sessions (2 of which involved teaching) embedded in the assessment battery; and this fast mapping explained unique variance in their spelling achievement over and beyond their orthographic and phonological coding abilities and correlated significantly with current and next-year spelling achievement.
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Comment on ``Deterministic Single-Photon Source for Distributed Quantum Networking''
NASA Astrophysics Data System (ADS)
Kimble, H. J.
2003-06-01
A Comment on the Letter by
Axel Kuhn, Markus Hennrich, and Gerhard Rempe, Phys. Rev. Lett. PRLTAO 0031-9007 89, 067901 (2002). The authors of the Letter offer a Reply. -
[A case of pure agraphia due to left parietal lobe infarction].
Yaguchi, H; Bando, M; Kubo, T; Ohi, M; Suzuki, K
1998-06-01
We reported a case of a 63-year-old right handed man with pure agraphia due to the left parietal lobe infarction. The characteristics of agraphia in the patient were as follows. 1) The written letters were generally recognizable and well formed. 2) He succeeded in pointing to single Kana letter named by the examiner from the Japanese syllabary, but missed in pointing to Kana words. 3) Further, it took more time for the patient to point to even single Kana letter than for the control. 4) Most errors in Kana writing was substitution. Errors in Kanji writing are partial lacking or no response. But his ability in Kanji writing was facilitated by visual cues. He was unable to describe the Hen (a left-hand radical) and Tsukuri (the body) of some Kanji letters and to name some Kanji letters when their Hen and Tsukuri were orally given. We classified pure agraphia into two types out of some references. In one type (Type 1), letters in writing are poorly formed, but the ability to make words with the methods other than writing, for example spelling with anagrams or typing are preserved. In another type (Type 2), letters in writing were well-formed, but spelling with anagrams or typing were abnormal. Type 1 agraphia could result from the only deficit of graphic motor engram, while type 2 agraphia could be caused by the deficits other than graphic motor engram. Agraphia in this case belongs to the type 2. The features of agraphia in this case suggested that his agraphia was caused by a disorder in recalling graphemes of letters, and in arranging at least of Kana-letters.
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[Design and implementation of controlling smart car systems using P300 brain-computer interface].
Wang, Jinjia; Yang, Chengjie; Hu, Bei
2013-04-01
Using human electroencephalogram (EEG) to control external devices in order to achieve a variety of functions has been focus of the field of brain-computer interface (BCI) research. P300 is experiments which stimulate the eye to produce EEG by using letters flashing, and then identify the corresponding letters. In this paper, some improvements based on the P300 experiments were made??. Firstly, the matrix of flashing letters were modified into words which represent a certain sense. Secondly, the BCI2000 procedures were added with the corresponding source code. Thirdly, the smart car systems were designed using the radiofrequency signal. Finally it was realized that the evoked potentials were used to control the state of the smart car.
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Peden, Ann R
2018-03-01
Dr. Hildegard Peplau, considered to be our first modern Nurse theorist and the Mother of Psychiatric Nursing, was a prolific writer, engaging in correspondence with colleagues and students who sought her professional and theoretical expertise. Through these letters, she influenced psychiatric nursing while maintaining a broad international network of professional colleagues. An analysis of letters, written between 1990 and 1998, provides insights into Peplau's last decade of professional life and a model of how to support the next generation of nurse scholars. Using content analysis, 24 letters received between 1990 and 1998 were read, reread, and coded. Recurring themes were identified. Three themes were identified. These include Peplau, the Person: Living a Life of Professional Balance; Lighting a Spark: Investing in the Next Generation; and Work in the Vineyards of Nursing: Maintaining a Life of Scholarship. The letters depict Peplau's keen intellect, her wide professional network, her leisure time spent with family and friends, and her own work to assure that her theoretical legacy continued. Peplau's insights continue to be relevant as psychiatric mental health nursing leaders engage in activities to support the next generation of scholars and leaders.
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Evaluation of the DRAGON code for VHTR design analysis.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Taiwo, T. A.; Kim, T. K.; Nuclear Engineering Division
2006-01-12
This letter report summarizes three activities that were undertaken in FY 2005 to gather information on the DRAGON code and to perform limited evaluations of the code performance when used in the analysis of the Very High Temperature Reactor (VHTR) designs. These activities include: (1) Use of the code to model the fuel elements of the helium-cooled and liquid-salt-cooled VHTR designs. Results were compared to those from another deterministic lattice code (WIMS8) and a Monte Carlo code (MCNP). (2) The preliminary assessment of the nuclear data library currently used with the code and libraries that have been provided by themore » IAEA WIMS-D4 Library Update Project (WLUP). (3) DRAGON workshop held to discuss the code capabilities for modeling the VHTR.« less
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This August 9, 2016 letter from EPA approves, with modifications, the petition from Poet Biorefining-Fostoria, LLC, regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the Clean Air Act for renewable fuel (D-code 6)
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This August 9, 2016 letter from EPA approves,wtih modifications, the petition from Poet Biorefining-Leipsic, LLC, regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs
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Joule Unlimited Technologies Approval
This March 29 letter from EPA approves the petition from Joule Unlimited Technologies, Inc. regarding ethanol produced through the Joule Helioculture Process under the Clean Air Act for renewable fuel [D-code 5] RINs under the RFS program.
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Letter-Sound Reading: Teaching Preschool Children Print-to-Sound Processing
2015-01-01
This intervention study investigated the growth of letter sound reading and growth of consonant–vowel–consonant (CVC) word decoding abilities for a representative sample of 41 US children in preschool settings. Specifically, the study evaluated the effectiveness of a 3-step letter-sound teaching intervention in teaching pre-school children to decode, or read, single letters. The study compared a control group, which received the preschool’s standard letter-sound instruction, to an intervention group which received a 3-step letter-sound instruction intervention. The children’s growth in letter-sound reading and CVC word decoding abilities were assessed at baseline and 2, 4, 6 and 8 weeks. When compared to the control group, the growth of letter-sound reading ability was slightly higher for the intervention group. The rate of increase in letter-sound reading was significantly faster for the intervention group. In both groups, too few children learned to decode any CVC words to allow for analysis. Results of this study support the use of the intervention strategy in preschools for teaching children print-to-sound processing. PMID:26839494
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2014-02-26
through RF filtering . Subsequently, this modulated signal is used in a cutback experiment with a passive fiber . Studies describing enhancement factors...to filter out higher order modes [3]. However, in order to maintain single-mode (diffraction limited) operation, conventional step-index fiber core...Letters 36, 2686-2688 (2011). [3] J. P. Koplaw, D. Kliner, and L. Goldberg, “Single-mode operation of a coiled multimode fiber amplifier,” Optics Letters
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This May 9, 2016 letter from EPA approves the petition from Didion Ethanol, LLC, regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs under the RFS program.
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This September 19, 2016 letter from EPA approves the petition from Poet Biorefining-Lake Crystal, regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs under the RFS
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Orthographic similarity: the case of "reversed anagrams".
Morris, Alison L; Still, Mary L
2012-07-01
How orthographically similar are words such as paws and swap, flow and wolf, or live and evil? According to the letter position coding schemes used in models of visual word recognition, these reversed anagrams are considered to be less similar than words that share letters in the same absolute or relative positions (such as home and hose or plan and lane). Therefore, reversed anagrams should not produce the standard orthographic similarity effects found using substitution neighbors (e.g., home, hose). Simulations using the spatial coding model (Davis, Psychological Review 117, 713-758, 2010), for example, predict an inhibitory masked-priming effect for substitution neighbor word pairs but a null effect for reversed anagrams. Nevertheless, we obtained significant inhibitory priming using both stimulus types (Experiment 1). We also demonstrated that robust repetition blindness can be obtained for reversed anagrams (Experiment 2). Reversed anagrams therefore provide a new test for models of visual word recognition and orthographic similarity.
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Infant formula companies battle for breast.
1996-01-01
The infant formula manufacturer Mead Johnson has filed a lawsuit in Ontario courts against its competitor Ross Abbott for false advertising of its new Similac brand of infant formula. Mead Johnson contends that the Ross Abbott advertisement of Similac as providing benefits similar to mother's milk is false and misleading. Breast feeding specialists agree with Mead Johnson's claim. Yet, one year earlier, Mead Johnson claimed that its infant formula is modeled after mother's milk. The Infant Feeding Action Coalition (INFACT) Canada had complained to the Competition Bureau that called for Mead Johnson to cease its claim. Court documents reveal that both companies disregard the World Health Organization (WHO) International Code of Marketing of Breast Milk Substitutes. This code prohibits manufacturers from advertising directly to pregnant women and mothers. Two Ross Abbott spokespersons have different responses to their advertising practices: increasing emphasis on consumer promotion and support of the principle and objective of the WHO Code. Both companies have sought support of health professionals in Canada. In July 1996 Mead Johnson sent letters to about 7000 clinicians declaring "as someone who cares about infant health and nutrition as much as we do" and "...the most alarming concern is that, although there is no scientific basis for such claims, mothers believe them to be true." Ross Abbott responded to these letters by sending physicians letters declaring "Our business is built on trust, and we assure you that you may trust in Similac Advance and the benefits we have ascribed to it." The two companies will meet again in court on September 30, 1996.
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Scaltritti, Michele; Balota, David A.
2013-01-01
This present study examined accuracy and response latency of letter processing as a function of position within a horizontal array. In a series of 4 Experiments, target-strings were briefly (33 ms for Experiment 1 to 3, 83 ms for Experiment 4) displayed and both forward and backward masked. Participants then made a two alternative forced choice. The two alternative responses differed just in one element of the string, and position of mismatch was systematically manipulated. In Experiment 1, words of different lengths (from 3 to 6 letters) were presented in separate blocks. Across different lengths, there was a robust advantage in performance when the alternative response was different for the letter occurring at the first position, compared to when the difference occurred at any other position. Experiment 2 replicated this finding with the same materials used in Experiment 1, but with words of different lengths randomly intermixed within blocks. Experiment 3 provided evidence of the first position advantage with legal nonwords and strings of consonants, but did not provide any first position advantage for non-alphabetic symbols. The lack of a first position advantage for symbols was replicated in Experiment 4, where target-strings were displayed for a longer duration (83 ms). Taken together these results suggest that the first position advantage is a phenomenon that occurs specifically and selectively for letters, independent of lexical constraints. We argue that the results are consistent with models that assume a processing advantage for coding letters in the first position, and are inconsistent with the commonly held assumption in visual word recognition models that letters are equally processed in parallel independent of letter position. PMID:24012723
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Schumann, Anja; John, Ulrich; Ulbricht, Sabina; Rüge, Jeannette; Bischof, Gallus; Meyer, Christian
2008-11-01
This study examines tailored feedback letters of a smoking cessation intervention that is conceptually based on the transtheoretical model, from a content-based perspective. Data of 2 population-based intervention studies, both randomized controlled trials, with total N=1044 were used. The procedure of the intervention, the tailoring principle for the feedback letters, and the content of the intervention materials are described in detail. Theoretical and empirical frequencies of unique feedback letters are presented. The intervention system was able to generate a total of 1040 unique letters with normative feedback only, and almost half a million unique letters with normative and ipsative feedback. Almost every single smoker in contemplation, preparation, action, and maintenance had an empirically unique combination of tailoring variables and received a unique letter. In contrast, many smokers in precontemplation shared a combination of tailoring variables and received identical letters. The transtheoretical model provides an enormous theoretical and empirical variability of tailoring. However, tailoring for a major subgroup of smokers, i.e. those who do not intend to quit, needs improvement. Conceptual ideas for additional tailoring variables are discussed.
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Montana Advanced Biofuels Great Falls Approval
This November 20, 2015 letter from EPA approves the petition from Montana Advanced Biofuels, LLC, Great Falls facility, regarding ethanol produced through a dry mill process, qualifying under the Clean Air Act for advanced biofuel (D-code 5) and renewable
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Reading Acquisition and Beyond: Decoding Includes Cognition.
ERIC Educational Resources Information Center
Perfetti, Charles A.
1984-01-01
Focuses on (1) the acquisition and use of word representations and (2) the acquisition of the alphabetic code. Urges that instruction provide conditions to promote the learning of three types of representation--word forms, letter patterns, and mapping. (RDN)
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This November 19, 2015 letter from EPA approves the petition from CORN, LP, Goldfield facility, regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs under the RFS pro
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Berninger, V W
1988-10-01
A microcomputerized experiment, administered to 45 children in the 2nd, 5th, and 8th month of first grade, manipulated three variables: (a) stimulus unit (whole word or letter-by-letter presentation), (b) nature of stimulus information (phonically regular words, phonically irregular words, nonsense words, and letter strings, which differ in whether phonemic, orthographic, semantic, and/or name codes are available), and (c) linguistic task (lexical decision, naming, and written reproduction). Letter-by-letter presentation resulted in more accurate lexical decision and naming but not more accurate written reproduction. Interactions between nature of stimulus information and linguistic task occurred. Throughout the year, accuracy was greater for lexical decision than for naming or written reproduction. The superiority of lexical decision cannot be attributed to the higher probability of correct responses on a binary choice task because only consistently correct responses on repeated trials were analyzed. The earlier development of lexical decision, a receptive task, than of naming or written reproduction, production tasks, suggests that hidden units (Hinton & Sejnowski, 1986) in tertiary cortical areas may abstract visual-linguistic associations in printed words before production units in primary cortical areas can produce printed words orally or graphically.
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Lonigan, Christopher J.; Purpura, David J.; Wilson, Shauna B.; Walker, Patricia M.; Clancy-Menchetti, Jeanine
2013-01-01
Many preschool children are at risk for reading problems because of inadequate emergent literacy skills. Evidence supports the effectiveness of interventions to promote these skills, but questions remain about which intervention components work and whether combining intervention components will result in larger gains. In this study, 324 preschoolers (mean age = 54.32 months, SD = 5.88) from low-income backgrounds (46% girls and 54% boys; 82% African American, 14% White, and 4% other) were randomized to combinations of meaning-focused (dialogic reading or shared reading) and code-focused (phonological awareness, letter knowledge, or both) interventions or a control group. Interventions had statistically significant positive impacts only on measures of their respective skill domains. Combinations of interventions did not enhance outcomes across domains, indicating instructional needs in all areas of weakness for young children at risk for later reading difficulties. Less time for each intervention in the combined phonological awareness and letter knowledge intervention conditions, however, did not result in reduced effects relative to nearly twice as much time for each intervention when children received either only the phonological awareness intervention or only the letter knowledge intervention. This finding suggests that a relatively compact code-focused intervention can address the needs of children with weaknesses in both domains. PMID:23073367
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Phonologically-Based Priming in the Same-Different Task With L1 Readers.
Lupker, Stephen J; Nakayama, Mariko; Yoshihara, Masahiro
2018-02-01
The present experiment provides an investigation of a promising new tool, the masked priming same-different task, for investigating the orthographic coding process. Orthographic coding is the process of establishing a mental representation of the letters and letter order in the word being read which is then used by readers to access higher-level (e.g., semantic) information about that word. Prior research (e.g., Norris & Kinoshita, 2008) had suggested that performance in this task may be based entirely on orthographic codes. As reported by Lupker, Nakayama, and Perea (2015a), however, in at least some circumstances, phonological codes also play a role. Specifically, even though their 2 languages are completely different orthographically, Lupker et al.'s Japanese-English bilinguals showed priming in this task when masked L1 primes were phonologically similar to L2 targets. An obvious follow-up question is whether Lupker et al.'s effect might have resulted from a strategy that was adopted by their bilinguals to aid in processing of, and memory for, the somewhat unfamiliar L2 targets. In the present experiment, Japanese readers responded to (Japanese) Kanji targets with phonologically identical primes (on "related" trials) being presented in a completely different but highly familiar Japanese script, Hiragana. Once again, significant priming effects were observed, indicating that, although performance in the masked priming same-different task may be mainly based on orthographic codes, phonological codes can play a role even when the stimuli being matched are familiar words from a reader's L1. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
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Mishler, Ada D; Neider, Mark B
2017-11-01
The redundant signals effect, a speed-up in response times with multiple targets compared to a single target in one display, is well-documented, with some evidence suggesting that it can occur even in conceptual processing when targets are presented bilaterally. The current study was designed to determine whether or not category-based redundant signals can speed up processing even without bilateral presentation. Toward that end, participants performed a go/no-go visual task in which they responded only to members of the target category (i.e., they responded only to numbers and did not respond to letters). Numbers and letters were presented along an imaginary vertical line in the center of the visual field. When the single signal trials contained a nontarget letter (Experiment 1), there was a significant redundant signals effect. The effect was not significant when the single-signal trials did not contain a nontarget letter (Experiments 2 and 3). The results indicate that, when targets are defined categorically and not presented bilaterally, the redundant signals effect may be an effect of reducing the presence of information that draws attention away from the target. This suggests that redundant signals may not speed up conceptual processing when interhemispheric presentation is not available. Copyright © 2017 Elsevier B.V. All rights reserved.
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Miscommunication across Cultures: The Case of Marketing in Indian English. Revised.
ERIC Educational Resources Information Center
Frank, Jane
A study of intercultural business communication problems compared three examples of direct marketing sales letters similar in function, format, content, and targeted recipient but originating in different cultures (India, England, and the United States) and companies. The letters were directed to a single prospective purchaser of "Who's…
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Contracting for Audit Services.
ERIC Educational Resources Information Center
Heifetz, Harry S.
1987-01-01
The Single Audit Act of 1984 requires most school districts receiving over $25,000 in federal funds to undergo financial audits. This article highlights requirements for selecting certified public accountants to perform the audit and suggests factors to be considered before drafting a contract or letter of engagement. A sample letter is included.…
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77 FR 64362 - Postal Rate and Classification Changes
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-19
.... Promotions As part of this filing, the Postal Service seeks approval of six promotions during calendar year.... Table 6--First-Class Mail Price Changes Percent First-class mail product change Single-Piece Letters and...-piece letter mail (including the Forever stamp), increases by one cent under the Postal Service's plan...
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Interactive Hangman Teaches Amino Acid Structures and Abbreviations
ERIC Educational Resources Information Center
Pennington, Britney O.; Sears, Duane; Clegg, Dennis O.
2014-01-01
We developed an interactive exercise to teach students how to draw the structures of the 20 standard amino acids and to identify the one-letter abbreviations by modifying the familiar game of "Hangman." Amino acid structures were used to represent single letters throughout the game. To provide additional practice in identifying…
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Code of Federal Regulations, 2010 CFR
2010-01-01
... financial management assistance. These services may assist you in resolving your present delinquency in your... delinquency. If you want to participate in this program, please sign the attached copy of this letter and...
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Resource Letter SPE-1: Single-Photon Experiments in the Undergraduate Laboratory
NASA Astrophysics Data System (ADS)
Galvez, Enrique J.
2014-11-01
This Resource Letter lists undergraduate-laboratory adaptations of landmark optical experiments on the fundamentals of quantum physics. Journal articles and websites give technical details of the adaptations, which offer students unique hands-on access to testing fundamental concepts and predictions of quantum mechanics. A selection of the original research articles that led to the implementations is included. These developments have motivated a rethinking of the way quantum mechanics is taught, so this Resource Letter also lists textbooks that provide these new approaches.
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Letter and symbol identification: No evidence for letter-specific crowding mechanisms.
Castet, Eric; Descamps, Marine; Denis-Noël, Ambre; Colé, Pascale
2017-09-01
It has been proposed that letters, as opposed to symbols, trigger specialized crowding processes, boosting identification of the first and last letters of words. This hypothesis is based on evidence that single-letter accuracy as a function of within-string position has a W shape (the classic serial position function [SPF] in psycholinguistics) whereas an inverted V shape is obtained when measured with symbols. Our main goal was to test the robustness of the latter result. Our hypothesis was that any letter/symbol difference might result from short-term visual memory processes (due to the partial report [PR] procedures used in SPF studies) rather than from crowding. We therefore removed the involvement of short-term memory by precueing target-item position and compared SPFs with precueing and postcueing. Perimetric complexity was stringently matched between letters and symbols. In postcueing conditions similar to previous studies, we did not reproduce the inverted V shape for symbols: Clear-cut W shapes were observed with an overall smaller accuracy for symbols compared to letters. This letter/symbol difference was dramatically reduced in precueing conditions in keeping with our prediction. Our results are not consistent with the claim that letter strings trigger specialized crowding processes. We argue that PR procedures are not fit to isolate crowding processes.
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1992-01-01
component and the forces it carried perform creditably, but losses were far smaller than anticipated. The units carried out their as- signed missions...problem of navigation was to be made as simple as possible. For security reasons each site was given a code name. Call signs were assigned to the site...boats. Each of these car- ried a Eureka beacon and a green holophane light, sending the as- signed code letter. These boats, serving as definite
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The effect of letter string length and report condition on letter recognition accuracy.
Raghunandan, Avesh; Karmazinaite, Berta; Rossow, Andrea S
Letter sequence recognition accuracy has been postulated to be limited primarily by low-level visual factors. The influence of high level factors such as visual memory (load and decay) has been largely overlooked. This study provides insight into the role of these factors by investigating the interaction between letter sequence recognition accuracy, letter string length and report condition. Letter sequence recognition accuracy for trigrams and pentagrams were measured in 10 adult subjects for two report conditions. In the complete report condition subjects reported all 3 or all 5 letters comprising trigrams and pentagrams, respectively. In the partial report condition, subjects reported only a single letter in the trigram or pentagram. Letters were presented for 100ms and rendered in high contrast, using black lowercase Courier font that subtended 0.4° at the fixation distance of 0.57m. Letter sequence recognition accuracy was consistently higher for trigrams compared to pentagrams especially for letter positions away from fixation. While partial report increased recognition accuracy in both string length conditions, the effect was larger for pentagrams, and most evident for the final letter positions within trigrams and pentagrams. The effect of partial report on recognition accuracy for the final letter positions increased as eccentricity increased away from fixation, and was independent of the inner/outer position of a letter. Higher-level visual memory functions (memory load and decay) play a role in letter sequence recognition accuracy. There is also suggestion of additional delays imposed on memory encoding by crowded letter elements. Copyright © 2016 Spanish General Council of Optometry. Published by Elsevier España, S.L.U. All rights reserved.
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12 CFR 160.120 - Letters of credit and other independent undertakings to pay against documents.
Code of Federal Regulations, 2012 CFR
2012-01-01
...: the applicable version of Article 5 of the Uniform Commercial Code (UCC) (1962, as amended 1990) or revised Article 5 of the UCC (as amended 1995) (available from West Publishing Co.); the Uniform Customs...
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12 CFR 160.120 - Letters of credit and other independent undertakings to pay against documents.
Code of Federal Regulations, 2013 CFR
2013-01-01
...: the applicable version of Article 5 of the Uniform Commercial Code (UCC) (1962, as amended 1990) or revised Article 5 of the UCC (as amended 1995) (available from West Publishing Co.); the Uniform Customs...
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12 CFR 160.120 - Letters of credit and other independent undertakings to pay against documents.
Code of Federal Regulations, 2014 CFR
2014-01-01
...: the applicable version of Article 5 of the Uniform Commercial Code (UCC) (1962, as amended 1990) or revised Article 5 of the UCC (as amended 1995) (available from West Publishing Co.); the Uniform Customs...
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ERIC Educational Resources Information Center
Lorenzen, Elizabeth A.; And Others
Directed especially at graduating college seniors, this paper contains information about employment interviews and how to prepare for them. Subjects discussed include the following: preparing for interviews (analyzing strengths and weaknesses, gathering information about the company); points to remember (dress codes, follow up thank-you letters);…
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Gillespie, Alex; Reader, Tom W
2016-01-01
Background Letters of complaint written by patients and their advocates reporting poor healthcare experiences represent an under-used data source. The lack of a method for extracting reliable data from these heterogeneous letters hinders their use for monitoring and learning. To address this gap, we report on the development and reliability testing of the Healthcare Complaints Analysis Tool (HCAT). Methods HCAT was developed from a taxonomy of healthcare complaints reported in a previously published systematic review. It introduces the novel idea that complaints should be analysed in terms of severity. Recruiting three groups of educated lay participants (n=58, n=58, n=55), we refined the taxonomy through three iterations of discriminant content validity testing. We then supplemented this refined taxonomy with explicit coding procedures for seven problem categories (each with four levels of severity), stage of care and harm. These combined elements were further refined through iterative coding of a UK national sample of healthcare complaints (n= 25, n=80, n=137, n=839). To assess reliability and accuracy for the resultant tool, 14 educated lay participants coded a referent sample of 125 healthcare complaints. Results The seven HCAT problem categories (quality, safety, environment, institutional processes, listening, communication, and respect and patient rights) were found to be conceptually distinct. On average, raters identified 1.94 problems (SD=0.26) per complaint letter. Coders exhibited substantial reliability in identifying problems at four levels of severity; moderate and substantial reliability in identifying stages of care (except for ‘discharge/transfer’ that was only fairly reliable) and substantial reliability in identifying overall harm. Conclusions HCAT is not only the first reliable tool for coding complaints, it is the first tool to measure the severity of complaints. It facilitates service monitoring and organisational learning and it enables future research examining whether healthcare complaints are a leading indicator of poor service outcomes. HCAT is freely available to download and use. PMID:26740496
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Restaurant Policies and Practices for Serving Raw Fish in Minnesota.
Hedeen, Nicole
2016-10-01
The number of restaurants serving sushi within Minnesota is continuously increasing. The practices and protocols of serving raw fish are complex and require detailed planning to ensure that food served to patrons will not cause illness. Although the popularity of sushi is increasing, there is a lack of research on food safety issues pertaining to preparation of raw fish and sushi rice. To address this gap, the Minnesota Department of Health Environmental Health Specialists Network Food program collected descriptive data on restaurant practices and policies concerning the service of raw fish and sushi rice in 40 Minnesota restaurants. At each restaurant, a specialist interviewed a restaurant manager, conducted an observation of the sushi prep areas in the restaurant kitchen, and reviewed parasite destruction letters and invoices from fish supplier(s). Over half of the restaurants (59%) were missing one or more of the parasite destruction letters from their fish supplier(s) guaranteeing that fish had been properly frozen to the time and temperature requirements in the Minnesota Food Code. A total of 42 parasite destruction letters from suppliers were observed; 10% were considered "adequate" letters. The majority of the letters were missing details pertaining to the types of fish frozen, the length of time fish were frozen, or details on what temperatures fish were held frozen or a combination of all three. Most restaurants were using time as a public health control for their sushi rice. For those restaurants using time as a public health control, 26% had a written procedure on-site, and approximately 53% were keeping track of time. Bare hand contact during sushi prep was observed in 17% of restaurants, and in more than 40% of the restaurants, at least one fish was mislabeled on the menu. Findings from this study indicate that many Minnesota restaurants are not complying with the Food Code requirements pertaining to parasite destruction for the service of raw fish or the use of time as a public health control for sushi rice.
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Richards, Todd L; Abbott, Robert D; Yagle, Kevin; Peterson, Dan; Raskind, Wendy; Berninger, Virginia W
2017-01-01
To understand mental self-government of the developing reading and writing brain, correlations of clustering coefficients on fMRI reading or writing tasks with BASC 2 Adaptivity ratings (time 1 only) or working memory components (time 1 before and time 2 after instruction previously shown to improve achievement and change magnitude of fMRI connectivity) were investigated in 39 students in grades 4 to 9 who varied along a continuum of reading and writing skills. A Philips 3T scanner measured connectivity during six leveled fMRI reading tasks (subword-letters and sounds, word-word-specific spellings or affixed words, syntax comprehension-with and without homonym foils or with and without affix foils, and text comprehension) and three fMRI writing tasks-writing next letter in alphabet, adding missing letter in word spelling, and planning for composing. The Brain Connectivity Toolbox generated clustering coefficients based on the cingulo-opercular (CO) network; after controlling for multiple comparisons and movement, significant fMRI connectivity clustering coefficients for CO were identified in 8 brain regions bilaterally (cingulate gyrus, superior frontal gyrus, middle frontal gyrus, inferior frontal gyrus, superior temporal gyrus, insula, cingulum-cingulate gyrus, and cingulum-hippocampus). BASC2 Parent Ratings for Adaptivity were correlated with CO clustering coefficients on three reading tasks (letter-sound, word affix judgments and sentence comprehension) and one writing task (writing next letter in alphabet). Before instruction, each behavioral working memory measure (phonology, orthography, morphology, and syntax coding, phonological and orthographic loops for integrating internal language and output codes, and supervisory focused and switching attention) correlated significantly with at least one CO clustering coefficient. After instruction, the patterning of correlations changed with new correlations emerging. Results show that the reading and writing brain's mental government, supported by both CO Adaptive Control and multiple working memory components, had changed in response to instruction during middle childhood/early adolescence.
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Powers, Martha; Saberi, Poune; Pepino, Richard; Strupp, Emily; Bugos, Eva; Cannuscio, Carolyn C
2015-06-01
Pennsylvania sits atop the Marcellus Shale, a reservoir of natural gas that was untapped until the 2004 introduction of unconventional natural gas drilling operations (UNGDO) in the state. Colloquially known as fracking, UNGDO is a controversial process that employs large volumes of water to fracture the shale and capture gas; it has become a multi-billion dollar industry in Pennsylvania. We analyzed letters to the editor of the most widely circulated local newspaper in the most heavily drilled county in Pennsylvania (Bradford County) in order to characterize residents' concerns and their involvement in popular epidemiology--the process by which citizens investigate risks associated with a perceived environmental threat. We reviewed 215 letters to the editor that referenced natural gas operations and were published by The Daily Review between January 1, 2008 and June 8, 2013. We used NVivo 10 to code and analyze letters and identify major themes. Nvivo is qualitative data analysis software (http://www.qsrinternational.com/products_nvivo.aspx) that allows researchers to code and analyze "unstructured" data, including text files of any type (e.g., interview transcripts, news articles, letters, archival materials) as well as photographs and videos. Nvivo can be used to classify, sort, query, comment on, and share data across a research group. Letters demonstrated citizen engagement in beginning and intermediate stages of lay epidemiology, as well as discord and stress regarding four main issues: socio-economic impacts, perceived threats to water, population growth and implications, and changes to the rural landscape. Residents called for stronger scientific evidence and a balance of economic development and health and environmental protections. Citizens' distress regarding UNGDO appeared to be exacerbated by a dearth of information to guide economic growth and health, environmental, and social concerns. This analysis proposes locally informed questions to guide future surveillance and research.
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The unique role of lexical accessibility in predicting kindergarten emergent literacy.
Verhoeven, Ludo; van Leeuwe, Jan; Irausquin, Rosemarie; Segers, Eliane
The goal of this longitudinal study was to examine how lexical quality predicts the emergence of literacy abilities in 169 Dutch kindergarten children before formal reading instruction has started. At the beginning of the school year, a battery of precursor measures associated with lexical quality was related to the emergence of letter knowledge and word decoding. Confirmatory factor analysis evidenced five domains related to lexical quality, i.e., vocabulary, phonological coding, phonological awareness, lexical retrieval and phonological working memory. Structural equation modeling showed that the development of letter knowledge during the year could be predicted from children's phonological awareness and lexical retrieval, and the emergence of word decoding from their phonological awareness and letter knowledge. It is concluded that it is primarily the accessibility of phonological representations in the mental lexicon that predicts the emergence of literacy in kindergarten.
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Intellectual system of identification of Arabic graphics
NASA Astrophysics Data System (ADS)
Abdoullayeva, Gulchin G.; Aliyev, Telman A.; Gurbanova, Nazakat G.
2001-08-01
The studies made by using the domain of graphic images allowed creating facilities of the artificial intelligence for letters, letter combinations etc. for various graphics and prints. The work proposes a system of recognition and identification of symbols of the Arabic graphics, which has its own specificity as compared to Latin and Cyrillic ones. The starting stage of the recognition and the identification is coding with further entry of information into a computer. Here the problem of entry is one of the essentials. For entry of a large volume of information in the unit of time a scanner is usually employed. Along with the scanner the authors suggest their elaboration of technical facilities for effective input and coding of the information. For refinement of symbols not identified from the scanner mostly for a small bulk of information the developed coding devices are used directly in the process of writing. The functional design of the software is elaborated on the basis of the heuristic model of the creative activity of a researcher and experts in the description and estimation of states of the weakly formalizable systems on the strength of the methods of identification and of selection of geometric features.
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Reading Ability and the Utilization of Orthographic Structure in Reading. Technical Report No. 515.
ERIC Educational Resources Information Center
Massaro, Dominic W.; Taylor, Glen A.
Previous research has demonstrated that readers utilize orthographic structure in their perceptual recognition of letter strings. Two experiments were conducted to assess whether this utilization varied with reading ability. Anagrams of words were made to create strings that orthogonally combined high and low single letter positional frequency and…
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Brief Experimental Analysis of Written Letter Formation: Single-Case Demonstration
ERIC Educational Resources Information Center
Burns, Matthew K.; Ganuza, Zoila M.; London, Rachel M.
2009-01-01
Many students experience difficulty in acquiring basic writing skills and educators need to efficiently address those deficits by implementing an intervention with a high likelihood for success. The current article demonstrates the utility of using a brief experimental analysis (BEA) to identify a letter-formation intervention for a second-grade…
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Crowding Affects Letters and Symbols Differently
ERIC Educational Resources Information Center
Grainger, Jonathan; Tydgat, Ilse; Issele, Joanna
2010-01-01
Five experiments examined crowding effects with letter and symbol stimuli. Experiments 1 through 3 compared 2-alternative forced-choice (2AFC) identification accuracy for isolated targets presented left and right of fixation with targets flanked either by 2 other items of the same category or a single item situated to the right or left of targets.…
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Park, Joonkoo; Chiang, Crystal; Brannon, Elizabeth M.; Woldorff, Marty G.
2014-01-01
Recent functional magnetic resonance imaging research has demonstrated that letters and numbers are preferentially processed in distinct regions and hemispheres in the visual cortex. In particular, the left visual cortex preferentially processes letters compared to numbers, while the right visual cortex preferentially processes numbers compared to letters. Because letters and numbers are cultural inventions and are otherwise physically arbitrary, such a double dissociation is strong evidence for experiential effects on neural architecture. Here, we use the high temporal resolution of event-related potentials (ERPs) to investigate the temporal dynamics of the neural dissociation between letters and numbers. We show that the divergence between ERP traces to letters and numbers emerges very early in processing. Letters evoked greater N1 waves (latencies 140–170 ms) than did numbers over left occipital channels, while numbers evoked greater N1s than letters over the right, suggesting letters and numbers are preferentially processed in opposite hemispheres early in visual encoding. Moreover, strings of letters, but not single letters, elicited greater P2 ERP waves, (starting around 250 ms) than numbers did over the left hemisphere, suggesting that the visual cortex is tuned to selectively process combinations of letters, but not numbers, further along in the visual processing stream. Additionally, the processing of both of these culturally defined stimulus types differentiated from similar but unfamiliar visual stimulus forms (false fonts) even earlier in the processing stream (the P1 at 100 ms). These findings imply major cortical specialization processes within the visual system driven by experience with reading and mathematics. PMID:24669789
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Park, Joonkoo; Chiang, Crystal; Brannon, Elizabeth M; Woldorff, Marty G
2014-10-01
Recent fMRI research has demonstrated that letters and numbers are preferentially processed in distinct regions and hemispheres in the visual cortex. In particular, the left visual cortex preferentially processes letters compared with numbers, whereas the right visual cortex preferentially processes numbers compared with letters. Because letters and numbers are cultural inventions and are otherwise physically arbitrary, such a double dissociation is strong evidence for experiential effects on neural architecture. Here, we use the high temporal resolution of ERPs to investigate the temporal dynamics of the neural dissociation between letters and numbers. We show that the divergence between ERP traces to letters and numbers emerges very early in processing. Letters evoked greater N1 waves (latencies 140-170 msec) than did numbers over left occipital channels, whereas numbers evoked greater N1s than letters over the right, suggesting letters and numbers are preferentially processed in opposite hemispheres early in visual encoding. Moreover, strings of letters, but not single letters, elicited greater P2 ERP waves (starting around 250 msec) than numbers did over the left hemisphere, suggesting that the visual cortex is tuned to selectively process combinations of letters, but not numbers, further along in the visual processing stream. Additionally, the processing of both of these culturally defined stimulus types differentiated from similar but unfamiliar visual stimulus forms (false fonts) even earlier in the processing stream (the P1 at 100 msec). These findings imply major cortical specialization processes within the visual system driven by experience with reading and mathematics.
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Implied reading direction and prioritization of letter encoding.
Holcombe, Alex O; Nguyen, Elizabeth H L; Goodbourn, Patrick T
2017-10-01
Capacity limits hinder processing of multiple stimuli, contributing to poorer performance for identifying two briefly presented letters than for identifying a single letter. Higher accuracy is typically found for identifying the letter on the left, which has been attributed to a right-hemisphere dominance for selective attention. Here, we use rapid serial visual presentation (RSVP) of letters in two locations at once. The letters to be identified are simultaneous and cued by rings. In the first experiment, we manipulated implied reading direction by rotating or mirror-reversing the letters to face to the left rather than to the right. The left-side performance advantage was eliminated. In the second experiment, letters were positioned above and below fixation, oriented such that they appeared to face downward (90° clockwise rotation) or upward (90° counterclockwise rotation). Again consistent with an effect of implied reading direction, performance was better for the top position in the downward condition, but not in the upward condition. In both experiments, mixture modeling of participants' report errors revealed that attentional sampling from the two locations was approximately simultaneous, ruling out the theory that the letter on one side was processed first, followed by a shift of attention to sample the other letter. Thus, the orientation of the letters apparently controls not when the letters are sampled from the scene, but rather the dynamics of a subsequent process, such as tokenization or memory consolidation. Implied reading direction appears to determine the letter prioritized at a high-level processing bottleneck. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
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12 CFR 390.267 - Letters of credit and other independent undertakings to pay against documents.
Code of Federal Regulations, 2014 CFR
2014-01-01
... applicable version of Article 5 of the Uniform Commercial Code (UCC) (1962, as amended 1990) or revised Article 5 of the UCC (as amended 1995) (available from West Publishing Co., 1/800/328-4880); the Uniform...
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12 CFR 390.267 - Letters of credit and other independent undertakings to pay against documents.
Code of Federal Regulations, 2012 CFR
2012-01-01
... applicable version of Article 5 of the Uniform Commercial Code (UCC) (1962, as amended 1990) or revised Article 5 of the UCC (as amended 1995) (available from West Publishing Co., 1/800/328-4880); the Uniform...
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12 CFR 390.267 - Letters of credit and other independent undertakings to pay against documents.
Code of Federal Regulations, 2013 CFR
2013-01-01
... applicable version of Article 5 of the Uniform Commercial Code (UCC) (1962, as amended 1990) or revised Article 5 of the UCC (as amended 1995) (available from West Publishing Co., 1/800/328-4880); the Uniform...
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FIR Filter of DS-CDMA UWB Modem Transmitter
NASA Astrophysics Data System (ADS)
Kang, Kyu-Min; Cho, Sang-In; Won, Hui-Chul; Choi, Sang-Sung
This letter presents low-complexity digital pulse shaping filter structures of a direct sequence code division multiple access (DS-CDMA) ultra wide-band (UWB) modem transmitter with a ternary spreading code. The proposed finite impulse response (FIR) filter structures using a look-up table (LUT) have the effect of saving the amount of memory by about 50% to 80% in comparison to the conventional FIR filter structures, and consequently are suitable for a high-speed parallel data process.
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New syndrome decoder for (n, 1) convolutional codes
NASA Technical Reports Server (NTRS)
Reed, I. S.; Truong, T. K.
1983-01-01
The letter presents a new syndrome decoding algorithm for the (n, 1) convolutional codes (CC) that is different and simpler than the previous syndrome decoding algorithm of Schalkwijk and Vinck. The new technique uses the general solution of the polynomial linear Diophantine equation for the error polynomial vector E(D). A recursive, Viterbi-like, algorithm is developed to find the minimum weight error vector E(D). An example is given for the binary nonsystematic (2, 1) CC.
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Beneventi, Harald; Tønnessen, Finn Egil; Ersland, Lars
2009-01-01
Dyslexia is primarily associated with a phonological processing deficit. However, the clinical manifestation also includes a reduced verbal working memory (WM) span. It is unclear whether this WM impairment is caused by the phonological deficit or a distinct WM deficit. The main aim of this study was to investigate neuronal activation related to phonological storage and rehearsal of serial order in WM in a sample of 13-year-old dyslexic children compared with age-matched nondyslexic children. A sequential verbal WM task with two tasks was used. In the Letter Probe task, the probe consisted of a single letter and the judgment was for the presence or absence of that letter in the prior sequence of six letters. In the Sequence Probe (SP) task, the probe consisted of all six letters and the judgment was for a match of their serial order with the temporal order in the prior sequence. Group analyses as well as single-subject analysis were performed with the statistical parametric mapping software SPM2. In the Letter Probe task, the dyslexic readers showed reduced activation in the left precentral gyrus (BA6) compared to control group. In the Sequence Probe task, the dyslexic readers showed reduced activation in the prefrontal cortex and the superior parietal cortex (BA7) compared to the control subjects. Our findings suggest that a verbal WM impairment in dyslexia involves an extended neural network including the prefrontal cortex and the superior parietal cortex. Reduced activation in the left BA6 in both the Letter Probe and Sequence Probe tasks may be caused by a deficit in phonological processing. However, reduced bilateral activation in the BA7 in the Sequence Probe task only could indicate a distinct working memory deficit in dyslexia associated with temporal order processing.
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The PIG in sPrInG: evidence on letter grouping from the reading of buried words.
Humphreys, Glyn W; Mayall, Kate; Cooper, Adam C G
2003-12-01
We introduce a novel procedure for investigating factors that determine selective attention to letters in words. Participants were presented with words (in Experiments 1 and 3) and nonwords (in Experiment 2) that contained a buried word whose letters differed in color relative to the other letters present (e.g., pig, in spring). The strings were presented in single case or mixed case, keeping the letters of the buried words in one case (SpRiNg). The time in which the whole stimulus was named was shorter for same-case than for mixed-case strings (for spring: spring < SpRiNg). In contrast, the time in which buried words were named was shorter in mixed- than in same-case strings (for pig: spring > SpRiNg). Across items, the effects of case mixing were negatively correlated across the two tasks. The positive effect of case mixing for buried words also occurred irrespective of whether the whole string was a word or a nonword, and there were contributions from similarity of both letter size and case. The results suggest that case mixing can facilitate selective attention to letters, which is otherwise disrupted by size- and case-based grouping across letter strings. The study provides evidence for letter grouping using size and case information.
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Is visual image segmentation a bottom-up or an interactive process?
Vecera, S P; Farah, M J
1997-11-01
Visual image segmentation is the process by which the visual system groups features that are part of a single shape. Is image segmentation a bottom-up or an interactive process? In Experiments 1 and 2, we presented subjects with two overlapping shapes and asked them to determine whether two probed locations were on the same shape or on different shapes. The availability of top-down support was manipulated by presenting either upright or rotated letters. Subjects were fastest to respond when the shapes corresponded to familiar shapes--the upright letters. In Experiment 3, we used a variant of this segmentation task to rule out the possibility that subjects performed same/different judgments after segmentation and recognition of both letters. Finally, in Experiment 4, we ruled out the possibility that the advantage for upright letters was merely due to faster recognition of upright letters relative to rotated letters. The results suggested that the previous effects were not due to faster recognition of upright letters; stimulus familiarity influenced segmentation per se. The results are discussed in terms of an interactive model of visual image segmentation.
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Lott, Susan Nitzberg; Carney, Aimee Syms; Glezer, Laurie S; Friedman, Rhonda B
2010-11-01
BACKGROUND: Letter-by-letter readers identify each letter of the word they are reading serially in left to right order before recognizing the word. When their letter naming is also impaired, letter-by-letter reading is inaccurate and can render even single word reading very poor. Tactile and/or kinesthetic strategies have been reported to improve reading in these patients, but only under certain conditions or for a limited set of stimuli. AIMS: The primary aim of the current study was to determine whether a tactile/kinesthetic treatment could significantly improve reading specifically under normal reading conditions, i.e. reading untrained words presented in free vision and read without overt use of the strategy. METHODS #ENTITYSTARTX00026; PROCEDURES: Three chronic letter-by-letter readers participated in a tactile/kinesthetic treatment aimed at first improving letter naming accuracy (phase 1) and then letter-by-letter reading speed (phase 2). In a multiple case series design, accuracy and speed of reading untrained words without overt use of the trained tactile/kinesthetic strategy was assessed before phase 1, after phase 1 and again after phase 2. OUTCOMES #ENTITYSTARTX00026; RESULTS: All three patients significantly improved both their speed and accuracy reading untrained words without overt use of the trained tactile/kinesthetic strategy. All three patients required the additional practice in phase 2 to achieve significant improvement. Treatment did not target sentence level reading, yet two of the three patients became so adept that they could read entire sentences. CONCLUSIONS: This study replicates previous findings on the efficacy of tactile/kinesthetic treatment for letter-by-letter readers with poor letter naming. It further demonstrates that this treatment can alter cognitive processing such that words never specifically trained can be read in free vision without overtly using the trained strategy. The data suggest that an important element in achieving this level of generalization is continuing training beyond the point of initial mastery (i.e. accurate letter naming).
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Lott, Susan Nitzberg; Carney, Aimee Syms; Glezer, Laurie S.; Friedman, Rhonda B.
2010-01-01
Background Letter-by-letter readers identify each letter of the word they are reading serially in left to right order before recognizing the word. When their letter naming is also impaired, letter-by-letter reading is inaccurate and can render even single word reading very poor. Tactile and/or kinesthetic strategies have been reported to improve reading in these patients, but only under certain conditions or for a limited set of stimuli. Aims The primary aim of the current study was to determine whether a tactile/kinesthetic treatment could significantly improve reading specifically under normal reading conditions, i.e. reading untrained words presented in free vision and read without overt use of the strategy. Methods & Procedures Three chronic letter-by-letter readers participated in a tactile/kinesthetic treatment aimed at first improving letter naming accuracy (phase 1) and then letter-by-letter reading speed (phase 2). In a multiple case series design, accuracy and speed of reading untrained words without overt use of the trained tactile/kinesthetic strategy was assessed before phase 1, after phase 1 and again after phase 2. Outcomes & Results All three patients significantly improved both their speed and accuracy reading untrained words without overt use of the trained tactile/kinesthetic strategy. All three patients required the additional practice in phase 2 to achieve significant improvement. Treatment did not target sentence level reading, yet two of the three patients became so adept that they could read entire sentences. Conclusions This study replicates previous findings on the efficacy of tactile/kinesthetic treatment for letter-by-letter readers with poor letter naming. It further demonstrates that this treatment can alter cognitive processing such that words never specifically trained can be read in free vision without overtly using the trained strategy. The data suggest that an important element in achieving this level of generalization is continuing training beyond the point of initial mastery (i.e. accurate letter naming). PMID:21170161
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Green, Nancy
2005-04-01
We developed a Bayesian network coding scheme for annotating biomedical content in layperson-oriented clinical genetics documents. The coding scheme supports the representation of probabilistic and causal relationships among concepts in this domain, at a high enough level of abstraction to capture commonalities among genetic processes and their relationship to health. We are using the coding scheme to annotate a corpus of genetic counseling patient letters as part of the requirements analysis and knowledge acquisition phase of a natural language generation project. This paper describes the coding scheme and presents an evaluation of intercoder reliability for its tag set. In addition to giving examples of use of the coding scheme for analysis of discourse and linguistic features in this genre, we suggest other uses for it in analysis of layperson-oriented text and dialogue in medical communication.
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Is a Genome a Codeword of an Error-Correcting Code?
Kleinschmidt, João H.; Silva-Filho, Márcio C.; Bim, Edson; Herai, Roberto H.; Yamagishi, Michel E. B.; Palazzo, Reginaldo
2012-01-01
Since a genome is a discrete sequence, the elements of which belong to a set of four letters, the question as to whether or not there is an error-correcting code underlying DNA sequences is unavoidable. The most common approach to answering this question is to propose a methodology to verify the existence of such a code. However, none of the methodologies proposed so far, although quite clever, has achieved that goal. In a recent work, we showed that DNA sequences can be identified as codewords in a class of cyclic error-correcting codes known as Hamming codes. In this paper, we show that a complete intron-exon gene, and even a plasmid genome, can be identified as a Hamming code codeword as well. Although this does not constitute a definitive proof that there is an error-correcting code underlying DNA sequences, it is the first evidence in this direction. PMID:22649495
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33 CFR 401.68 - Explosives permission letter.
Code of Federal Regulations, 2014 CFR
2014-07-01
..., DEPARTMENT OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Dangerous Cargo § 401.68 Explosives... Dangerous Goods Regulations (Canada), the United States regulations under the Dangerous Cargo Act and the International Maritime Dangerous Goods Code, may be made to the St. Lawrence Seaway Management Corporation, 202...
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33 CFR 401.68 - Explosives Permission Letter.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., DEPARTMENT OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Dangerous Cargo § 401.68 Explosives... Regulations respecting the Carriage of Dangerous Goods, the United States Regulations under the Dangerous Cargo Act and the International Maritime Dangerous Goods Code may be made to the Saint Lawrence Seaway...
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33 CFR 401.68 - Explosives Permission Letter.
Code of Federal Regulations, 2012 CFR
2012-07-01
..., DEPARTMENT OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Dangerous Cargo § 401.68 Explosives... Regulations respecting the Carriage of Dangerous Goods, the United States Regulations under the Dangerous Cargo Act and the International Maritime Dangerous Goods Code may be made to the Saint Lawrence Seaway...
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Going Digital - The Transition from Mark IV to DBBC at Onsala
NASA Astrophysics Data System (ADS)
Kareinen, Niko; Haas, Rüdiger; La Porta, Laura; Bertarini, Alessandra
2014-12-01
The Onsala Space Observatory is currently equipped with both a VLBI Mark IV rack and a digital BBC (DBBC). The Mark IV rack at Onsala has been used operationally for both astronomical and geodetic VLBI for more than 40 years. In 2011, Onsala purchased a DBBC and we started to test it and to gain experience with the new device, both for astronomical and geodetic VLBI. The DBBC was upgraded several times and the Field System (FS) interface was implemented. We did parallel recordings, with both the old Mark IV/Mark 5A system and the new DBBC/Mark 5B+ system, during numerous geodetic VLBI sessions. Several R1, T2, and Euro sessions were correlated during the last two years by the Bonn correlator with Onsala being included both as an analog station (two-letter code On) and as a digital station (two-letter code Od). We present results from these parallel sessions, both results from the original correlation and results from the analysis of the corresponding databases.
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Teaching Adults to Read Braille Using Phonological Methods: Single-Case Studies
ERIC Educational Resources Information Center
Crawford, Shauna; Elliott, Robert T.
2009-01-01
Four women with visual impairments were taught 13 braille letters as phonemes and another 13 braille letters as graphemes and then were taught 10 braille words as onset-rime and another 10 braille words as whole words. Phoneme and onset-rime instruction resulted in faster and more accurate performance. (Contains 1 table and 2 figures.)
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ERIC Educational Resources Information Center
Crump, Matthew J. C.; Logan, Gordon D.
2010-01-01
Routine actions are commonly assumed to be controlled by hierarchically organized processes and representations. In the domain of typing theories, word-level information is assumed to activate the constituent keystrokes required to type each letter in a word. We tested this assumption directly using a novel single-letter probe technique. Subjects…
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ERIC Educational Resources Information Center
Lauer, Patricia A.; And Others
1976-01-01
This experiment attempts to maximize orthographic while reducing semantic bases for processing by using lists of words from a single category (girl's first names), presenting the first letter as a cue for each word during both study and recall trials, and blocking together all words with the same first letter. (Author)
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Learning to identify contrast-defined letters in peripheral vision
Chung, Susana T.L.; Levi, Dennis M.; Li, Roger W.
2009-01-01
Performance for identifying luminance-defined letters in peripheral vision improves with training. The purpose of the present study was to examine whether performance for identifying contrast-defined letters also improves with training in peripheral vision, and whether any improvement transfers to luminance-defined letters. Eight observers were trained to identify contrast-defined letters presented singly at 10° eccentricity in the inferior visual field. Before and after training, we measured observers’ thresholds for identifying luminance-defined and contrast-defined letters, embedded within a field of white luminance noise (maximum luminance contrast = 0, 0.25, and 0.5), at the same eccentric location. Each training session consisted of 10 blocks (100 trials per block) of identifying contrast-defined letters at a background noise contrast of 0.5. Letters (x-height = 4.2°) were the 26 lowercase letters of the Times-Roman alphabet. Luminance-defined letters were generated by introducing a luminance difference between the stimulus letter and its mid-gray background. The background noise covered both the letter and its background. Contrast-defined letters were generated by introducing a differential noise contrast between the group of pixels that made up the stimulus letter and the group of pixels that made up the background. Following training, observers showed a significant reduction in threshold for identifying contrast-defined letters (p < 0.0001). Averaged across observers and background noise contrasts, the reduction was 25.8%, with the greatest reduction (32%) occurring at the trained background noise contrast. There was virtually no transfer of improvement to luminance-defined letters, or to an untrained letter size (2× original), or an untrained retinal location (10° superior field). In contrast, learning transferred completely to the untrained contralateral eye. Our results show that training improves performance for identifying contrast-defined letters in peripheral vision. This perceptual learning effect seems to be stimulus-specific, as it shows no transfer to the identification of luminance-defined letters. The complete interocular transfer, and the retinotopic (retinal location) and size specificity of the learning effect are consistent with the properties of neurons in early visual area V2. PMID:16337252
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2011-04-01
from the survey litho code list if a survey form was sent or independently if only a letter was sent. Ticket Numbers for Web Survey Access Prior...variables BATCH, SERIAL, and LITHO uniquely identify each returned survey. LITHO is the lithocode scanned from the survey. BATCH and SERIAL are the...Uned 593 LEADERSAT Tabs: Leadership Satisfaction Scale- Q11 176 LITHO * Litho code 1086 MAILTYP* Mail Type 1087 MENTOR 12. [12] Do you have a
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Orhan, Umut; Erdogmus, Deniz; Roark, Brian; Purwar, Shalini; Hild, Kenneth E.; Oken, Barry; Nezamfar, Hooman; Fried-Oken, Melanie
2013-01-01
Event related potentials (ERP) corresponding to a stimulus in electroencephalography (EEG) can be used to detect the intent of a person for brain computer interfaces (BCI). This paradigm is widely utilized to build letter-by-letter text input systems using BCI. Nevertheless using a BCI-typewriter depending only on EEG responses will not be sufficiently accurate for single-trial operation in general, and existing systems utilize many-trial schemes to achieve accuracy at the cost of speed. Hence incorporation of a language model based prior or additional evidence is vital to improve accuracy and speed. In this paper, we study the effects of Bayesian fusion of an n-gram language model with a regularized discriminant analysis ERP detector for EEG-based BCIs. The letter classification accuracies are rigorously evaluated for varying language model orders as well as number of ERP-inducing trials. The results demonstrate that the language models contribute significantly to letter classification accuracy. Specifically, we find that a BCI-speller supported by a 4-gram language model may achieve the same performance using 3-trial ERP classification for the initial letters of the words and using single trial ERP classification for the subsequent ones. Overall, fusion of evidence from EEG and language models yields a significant opportunity to increase the word rate of a BCI based typing system. PMID:22255652
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Kaspar, Mathias; Fette, Georg; Güder, Gülmisal; Seidlmayer, Lea; Ertl, Maximilian; Dietrich, Georg; Greger, Helmut; Puppe, Frank; Störk, Stefan
2018-04-17
Heart failure is the predominant cause of hospitalization and amongst the leading causes of death in Germany. However, accurate estimates of prevalence and incidence are lacking. Reported figures originating from different information sources are compromised by factors like economic reasons or documentation quality. We implemented a clinical data warehouse that integrates various information sources (structured parameters, plain text, data extracted by natural language processing) and enables reliable approximations to the real number of heart failure patients. Performance of ICD-based diagnosis in detecting heart failure was compared across the years 2000-2015 with (a) advanced definitions based on algorithms that integrate various sources of the hospital information system, and (b) a physician-based reference standard. Applying these methods for detecting heart failure in inpatients revealed that relying on ICD codes resulted in a marked underestimation of the true prevalence of heart failure, ranging from 44% in the validation dataset to 55% (single year) and 31% (all years) in the overall analysis. Percentages changed over the years, indicating secular changes in coding practice and efficiency. Performance was markedly improved using search and permutation algorithms from the initial expert-specified query (F1 score of 81%) to the computer-optimized query (F1 score of 86%) or, alternatively, optimizing precision or sensitivity depending on the search objective. Estimating prevalence of heart failure using ICD codes as the sole data source yielded unreliable results. Diagnostic accuracy was markedly improved using dedicated search algorithms. Our approach may be transferred to other hospital information systems.
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49 CFR 700.3 - Availability of documents, assistance, and information.
Code of Federal Regulations, 2012 CFR
2012-10-01
... segments dedicated to the following topics: Amtrak's computer system and its communication codes; interline... concerns in a letter or other written communication directed to the appropriate vice president or to the Director of Corporate Communications. Amtrak will bring such communications to the attention of the...
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49 CFR 700.3 - Availability of documents, assistance, and information.
Code of Federal Regulations, 2013 CFR
2013-10-01
... segments dedicated to the following topics: Amtrak's computer system and its communication codes; interline... concerns in a letter or other written communication directed to the appropriate vice president or to the Director of Corporate Communications. Amtrak will bring such communications to the attention of the...
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49 CFR 700.3 - Availability of documents, assistance, and information.
Code of Federal Regulations, 2011 CFR
2011-10-01
... segments dedicated to the following topics: Amtrak's computer system and its communication codes; interline... concerns in a letter or other written communication directed to the appropriate vice president or to the Director of Corporate Communications. Amtrak will bring such communications to the attention of the...
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49 CFR 700.3 - Availability of documents, assistance, and information.
Code of Federal Regulations, 2014 CFR
2014-10-01
... segments dedicated to the following topics: Amtrak's computer system and its communication codes; interline... concerns in a letter or other written communication directed to the appropriate vice president or to the Director of Corporate Communications. Amtrak will bring such communications to the attention of the...
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Code of Federal Regulations, 2013 CFR
2013-01-01
... or territory code, followed by two or three letters and four additional numbers. Official APHIS... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Definitions. 81.1 Section 81.1 Animals... § 81.1 Definitions. These definitions are applicable to this part: Accredited veterinarian. A...
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Code of Federal Regulations, 2014 CFR
2014-01-01
... or territory code, followed by two or three letters and four additional numbers. Official APHIS... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Definitions. 81.1 Section 81.1 Animals... § 81.1 Definitions. These definitions are applicable to this part: Accredited veterinarian. A...
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Fox, Adam T; Palmer, Roger D; Crossley, James G M; Sekaran, Devanitha; Trewavas, Eira S; Davies, Helena A
2004-08-01
To improve the quality of outpatient letters used as communication between hospital and primary care doctors. On 2 separate occasions, 15 unselected outpatient letters written by each of 7 hospital practitioners were rated by another hospital doctor and a general practitioner (GP) using the Sheffield Assessment Instrument for Letters (SAIL). Individualised feedback was provided to participants following the rating of the first set of letters. The audit cycle was completed 3 months later without forewarning by repeat assessment by the same hospital and GP assessors using the SAIL tool to see if there was any improvement in correspondence. Single centre: general paediatric outpatient department in a large district general hospital. All 7 doctors available for reassessment completed the audit loop, each providing 15 outpatient letters per assessment. The mean of the quality scores, derived for each letter from the summation of a 20-point checklist and a global score, improved from 23.3 (95% CI 22.1-24.4) to 26.6 (95% CI 25.8-27.4) (P = 0.001). The SAIL provides a feasible and reliable method of assessing the quality and content of outpatient clinic letters. This study demonstrates that it can also provide feedback with a powerful educational impact. This approach holds real potential for appraisal and revalidation, providing an effective means for the quality improvement required by clinical governance.
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Bernard, Jean-Baptiste; Aguilar, Carlos; Castet, Eric
2016-01-01
Reading speed is dramatically reduced when readers cannot use their central vision. This is because low visual acuity and crowding negatively impact letter recognition in the periphery. In this study, we designed a new font (referred to as the Eido font) in order to reduce inter-letter similarity and consequently to increase peripheral letter recognition performance. We tested this font by running five experiments that compared the Eido font with the standard Courier font. Letter spacing and x-height were identical for the two monospaced fonts. Six normally-sighted subjects used exclusively their peripheral vision to run two aloud reading tasks (with eye movements), a letter recognition task (without eye movements), a word recognition task (without eye movements) and a lexical decision task. Results show that reading speed was not significantly different between the Eido and the Courier font when subjects had to read single sentences with a round simulated gaze-contingent central scotoma (10° diameter). In contrast, Eido significantly decreased perceptual errors in peripheral crowded letter recognition (-30% errors on average for letters briefly presented at 6° eccentricity) and in peripheral word recognition (-32% errors on average for words briefly presented at 6° eccentricity). PMID:27074013
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Bernard, Jean-Baptiste; Aguilar, Carlos; Castet, Eric
2016-01-01
Reading speed is dramatically reduced when readers cannot use their central vision. This is because low visual acuity and crowding negatively impact letter recognition in the periphery. In this study, we designed a new font (referred to as the Eido font) in order to reduce inter-letter similarity and consequently to increase peripheral letter recognition performance. We tested this font by running five experiments that compared the Eido font with the standard Courier font. Letter spacing and x-height were identical for the two monospaced fonts. Six normally-sighted subjects used exclusively their peripheral vision to run two aloud reading tasks (with eye movements), a letter recognition task (without eye movements), a word recognition task (without eye movements) and a lexical decision task. Results show that reading speed was not significantly different between the Eido and the Courier font when subjects had to read single sentences with a round simulated gaze-contingent central scotoma (10° diameter). In contrast, Eido significantly decreased perceptual errors in peripheral crowded letter recognition (-30% errors on average for letters briefly presented at 6° eccentricity) and in peripheral word recognition (-32% errors on average for words briefly presented at 6° eccentricity).
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EFFECT OF METHOD OF READING TRAINING ON INITIAL LEARNING AND TRANSFER.
ERIC Educational Resources Information Center
JEFFREY, W.E.; SAMUELS, S. JAY
IN A THREE-STAGE STUDY OF THE EFFECTS OF THE PHONIC AND LOOK-SAY METHODS OF READING ON THE TRANSFER OF READING SKILLS, 60 KINDERGARTEN CHILDREN WERE DIVIDED INTO A LETTER GROUP, A WORD GROUP, AND A CONTROL GROUP. MATERIALS USED WERE SIX GRAPHEMES DESIGNED DIFFERENTLY FROM ENGLISH LETTERS AND ASSIGNED TO SIX SINGLE ENGLISH PHONEMES. DURING STAGE…
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The neural correlate of colour distances revealed with competing synaesthetic and real colours.
Laeng, Bruno; Hugdahl, Kenneth; Specht, Karsten
2011-03-01
Synaesthetes claim to perceive illusory colours when reading alphanumeric symbols so that two colours are said to be bound to the same letter or digit (i.e., the colour of the ink, e.g., black, and an additional, synaesthetic, colour). To explore the neural correlates of this phenomenon, we used a Stroop single-letter colour-naming task and found that distances in colour space between the illusory and real colours of a letter target (as computed from either the RGB or CIExyY coordinates of colours) systematically influenced the degree of neuronal activation in colour-processing brain regions. The synaesthetes also activated the same fronto-parietal network during the classic colour-word Stroop task and single-letter tasks. We conclude that the same neural substrate that supports the conscious experience of colour, as triggered by physical wavelength, supports the experience of synaesthetic colours. Thus, two colour attributes (one that is wavelength-dependent and one that is illusory) can be bound to the same stimulus position and simultaneously engage the colour areas in proportion to their similarity in colour space. Copyright © 2009 Elsevier Srl. All rights reserved.
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Ziegler, Johannes C; Bertrand, Daisy; Lété, Bernard; Grainger, Jonathan
2014-04-01
The present study used a variant of masked priming to track the development of 2 marker effects of orthographic and phonological processing from Grade 1 through Grade 5 in a cross-sectional study. Pseudohomophone (PsH) priming served as a marker for phonological processing, whereas transposed-letter (TL) priming was a marker for coarse-grained orthographic processing. The results revealed a clear developmental picture. First, the PsH priming effect was significant and remained stable across development, suggesting that phonology not only plays an important role in early reading development but continues to exert a robust influence throughout reading development. This finding challenges the view that more advanced readers should rely less on phonological information than younger readers. Second, the TL priming effect increased monotonically with grade level and reading age, which suggests greater reliance on coarse-grained orthographic coding as children become better readers. Thus, TL priming effects seem to be a good marker effect for children's ability to use coarse-grained orthographic coding to speed up direct lexical access in alphabetic languages. The results were predicted by the dual-route model of orthographic processing, which suggests that direct orthographic access is achieved through coarse-grained orthographic coding that tolerates some degree of flexibility in letter order. PsycINFO Database Record (c) 2014 APA, all rights reserved.
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Wavelet domain textual coding of Ottoman script images
NASA Astrophysics Data System (ADS)
Gerek, Oemer N.; Cetin, Enis A.; Tewfik, Ahmed H.
1996-02-01
Image coding using wavelet transform, DCT, and similar transform techniques is well established. On the other hand, these coding methods neither take into account the special characteristics of the images in a database nor are they suitable for fast database search. In this paper, the digital archiving of Ottoman printings is considered. Ottoman documents are printed in Arabic letters. Witten et al. describes a scheme based on finding the characters in binary document images and encoding the positions of the repeated characters This method efficiently compresses document images and is suitable for database research, but it cannot be applied to Ottoman or Arabic documents as the concept of character is different in Ottoman or Arabic. Typically, one has to deal with compound structures consisting of a group of letters. Therefore, the matching criterion will be according to those compound structures. Furthermore, the text images are gray tone or color images for Ottoman scripts for the reasons that are described in the paper. In our method the compound structure matching is carried out in wavelet domain which reduces the search space and increases the compression ratio. In addition to the wavelet transformation which corresponds to the linear subband decomposition, we also used nonlinear subband decomposition. The filters in the nonlinear subband decomposition have the property of preserving edges in the low resolution subband image.
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Lennox, Maria; Westerveld, Marleen F; Trembath, David
2018-04-01
This study examined the effectiveness of a classroom-based intervention programme aimed at improving the oral language and emergent literacy skills of students from low socio-economic, culturally diverse backgrounds within their first formal year of schooling ("prep"). Data from 137 students were available for analysis. Participants were from three primary schools located in Queensland, Australia. Eight classes were allocated to intervention and two classes acted as a business as usual control. All students received literacy instruction as per the Australian Curriculum. However, the intervention group received 24 weeks of scripted, classroom-based, book-based intervention targeting code- and meaning-related emergent literacy skills. All students were assessed individually pre- and post-intervention on code-related measures (i.e. letter identification and phonological awareness) and meaning-related measures (i.e. vocabulary, oral narrative comprehension and retell). All students made significant improvement over time for all measures. Students in the intervention group showed significantly more progress than the business as usual group on all measures, except for letter identification and oral narrative comprehension. This classroom-based book-based intervention can improve the code- and meaning-related emergent literacy skills of prep students from low socio-economic backgrounds and provide these students with the building blocks for successful literacy acquisition.
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78 FR 20332 - Changes in Flood Hazard Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-04
...), as shown on the Flood Insurance Rate Maps (FIRMs), and where applicable, in the supporting Flood... a Letter of Map Revision (LOMR), in accordance with Title 44, Part 65 of the Code of Federal... inspection at both the online location and the respective community map repository address listed in the...
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Episodic Contributions to Sequential Control: Learning from a Typist's Touch
ERIC Educational Resources Information Center
Crump, Matthew J. C.; Logan, Gordon D.
2010-01-01
Sequential control over routine action is widely assumed to be controlled by stable, highly practiced representations. Our findings demonstrate that the processes controlling routine actions in the domain of skilled typing can be flexibly manipulated by memory processes coding recent experience with typing particular words and letters. In two…
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Sudan: Humanitarian Crisis, Peace Talks, Terrorism, and U.S. Policy
2002-03-19
Congressional Research Service ˜ The Library of Congress CRS Issue Brief for Congress Received through the CRS Web Order Code IB98043 Sudan...as articulated by President Clinton in a 1996 letter to President Isaias of Eritrea supports regional efforts and seeks to isolate the NIF regime for
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Sudan: Humanitarian Crisis, Peace Talks, Terrorism, and U.S. Policy
2002-05-08
Congressional Research Service ˜ The Library of Congress Issue Brief for Congress Received through the CRS Web Order Code IB98043 Sudan...U.S. policy toward Sudan as articulated by President Clinton in a 1996 letter to President Isaias of Eritrea supports regional efforts and seeks to
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Management Oversight but Not Management
ERIC Educational Resources Information Center
McAdams, Donald R.
2004-01-01
Good board members and effective boards do not micromanage, but they are trustees for the public. They must accept responsibility for establishing and maintaining high ethical standards for themselves and all school district employees. They must ensure that everyone follows the law in letter and spirit. This means ethics codes,…
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1 CFR 21.11 - Standard organization of the Code of Federal Regulations.
Code of Federal Regulations, 2012 CFR
2012-01-01
... consists of the following structural units: (a) Titles, which are numbered consecutively in Arabic... are lettered consecutively in capitals throughout the chapter; (e) Parts, which are numbered in Arabic... Arabic throughout each part. A section number includes the number of the part followed by a period and...
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1 CFR 21.11 - Standard organization of the Code of Federal Regulations.
Code of Federal Regulations, 2011 CFR
2011-01-01
... consists of the following structural units: (a) Titles, which are numbered consecutively in Arabic... are lettered consecutively in capitals throughout the chapter; (e) Parts, which are numbered in Arabic... Arabic throughout each part. A section number includes the number of the part followed by a period and...
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1 CFR 21.11 - Standard organization of the Code of Federal Regulations.
Code of Federal Regulations, 2014 CFR
2014-01-01
... consists of the following structural units: (a) Titles, which are numbered consecutively in Arabic... are lettered consecutively in capitals throughout the chapter; (e) Parts, which are numbered in Arabic... Arabic throughout each part. A section number includes the number of the part followed by a period and...
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1 CFR 21.11 - Standard organization of the Code of Federal Regulations.
Code of Federal Regulations, 2013 CFR
2013-01-01
... consists of the following structural units: (a) Titles, which are numbered consecutively in Arabic... are lettered consecutively in capitals throughout the chapter; (e) Parts, which are numbered in Arabic... Arabic throughout each part. A section number includes the number of the part followed by a period and...
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Letter report on a straw-man modification of an ATC transponder for discrete address use
DOT National Transportation Integrated Search
1974-05-01
An experimental evaluation has been made of an RCA AVQ-65 airtraffic control transponder modified, in Mode D, so as to reply if and only if interrogated with its own preset reply code. Successful operation of the modified transponder was verified, an...
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47 CFR 13.207 - Preparing an examination.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Preparing an examination. (a) Each telegraphy message and each written question set administered to an... may obtain the written question sets from a supplier or other COLEM. (c) A telegraphy examination must... examination. Each five letters of the alphabet must be counted as one word or one code group. Each numeral...
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47 CFR 13.207 - Preparing an examination.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Preparing an examination. (a) Each telegraphy message and each written question set administered to an... may obtain the written question sets from a supplier or other COLEM. (c) A telegraphy examination must... examination. Each five letters of the alphabet must be counted as one word or one code group. Each numeral...
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47 CFR 13.207 - Preparing an examination.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Preparing an examination. (a) Each telegraphy message and each written question set administered to an... may obtain the written question sets from a supplier or other COLEM. (c) A telegraphy examination must... examination. Each five letters of the alphabet must be counted as one word or one code group. Each numeral...
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47 CFR 13.207 - Preparing an examination.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Preparing an examination. (a) Each telegraphy message and each written question set administered to an... may obtain the written question sets from a supplier or other COLEM. (c) A telegraphy examination must... examination. Each five letters of the alphabet must be counted as one word or one code group. Each numeral...
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Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Lot number. 987.102 Section 987.102 Agriculture... RIVERSIDE COUNTY, CALIFORNIA Administrative Rules Definitions § 987.102 Lot number. Lot number is synonymous with code and means a combination of letters or numbers, or both, acceptable to the Committee, showing...
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Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 8 2011-01-01 2011-01-01 false Lot number. 987.102 Section 987.102 Agriculture... RIVERSIDE COUNTY, CALIFORNIA Administrative Rules Definitions § 987.102 Lot number. Lot number is synonymous with code and means a combination of letters or numbers, or both, acceptable to the Committee, showing...
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Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 8 2013-01-01 2013-01-01 false Lot number. 987.102 Section 987.102 Agriculture... RIVERSIDE COUNTY, CALIFORNIA Administrative Rules Definitions § 987.102 Lot number. Lot number is synonymous with code and means a combination of letters or numbers, or both, acceptable to the Committee, showing...
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Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 8 2014-01-01 2014-01-01 false Lot number. 987.102 Section 987.102 Agriculture... RIVERSIDE COUNTY, CALIFORNIA Administrative Rules Definitions § 987.102 Lot number. Lot number is synonymous with code and means a combination of letters or numbers, or both, acceptable to the Committee, showing...
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Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 8 2012-01-01 2012-01-01 false Lot number. 987.102 Section 987.102 Agriculture... RIVERSIDE COUNTY, CALIFORNIA Administrative Rules Definitions § 987.102 Lot number. Lot number is synonymous with code and means a combination of letters or numbers, or both, acceptable to the Committee, showing...
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The Flip Side of Holland Type Congruence: Incongruence and Job Satisfaction
ERIC Educational Resources Information Center
Dik, Bryan J.; Strife, Samantha Roberts; Hansen, Jo-Ida C.
2010-01-01
This study examined the relationship between Holland type (Realistic, Investigative, Artistic, Social, Enterprising, and Conventional; Holland, 1959, 1997) congruence and incongruence (i.e., lack of ft between an occupation's 3-letter Holland code and a person's lowest 3 Holland interest types) and tested whether incongruence predicts unique…
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How to Write: A Barely Annotated Bibliography. Research Report.
ERIC Educational Resources Information Center
Miller, Lance A.
The references in this bibliography tend toward practical or "how to" strategies for writing. The 718 references are listed alphabetically in the bibliography section, with each citation followed by a code denoting its topical categories: (1) general "how to write," (2) "how to write" business letters, (3) stylistics,…
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Comparing the visual spans for faces and letters
He, Yingchen; Scholz, Jennifer M.; Gage, Rachel; Kallie, Christopher S.; Liu, Tingting; Legge, Gordon E.
2015-01-01
The visual span—the number of adjacent text letters that can be reliably recognized on one fixation—has been proposed as a sensory bottleneck that limits reading speed (Legge, Mansfield, & Chung, 2001). Like reading, searching for a face is an important daily task that involves pattern recognition. Is there a similar limitation on the number of faces that can be recognized in a single fixation? Here we report on a study in which we measured and compared the visual-span profiles for letter and face recognition. A serial two-stage model for pattern recognition was developed to interpret the data. The first stage is characterized by factors limiting recognition of isolated letters or faces, and the second stage represents the interfering effect of nearby stimuli on recognition. Our findings show that the visual span for faces is smaller than that for letters. Surprisingly, however, when differences in first-stage processing for letters and faces are accounted for, the two visual spans become nearly identical. These results suggest that the concept of visual span may describe a common sensory bottleneck that underlies different types of pattern recognition. PMID:26129858
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The level of audiovisual print-speech integration deficits in dyslexia.
Kronschnabel, Jens; Brem, Silvia; Maurer, Urs; Brandeis, Daniel
2014-09-01
The classical phonological deficit account of dyslexia is increasingly linked to impairments in grapho-phonological conversion, and to dysfunctions in superior temporal regions associated with audiovisual integration. The present study investigates mechanisms of audiovisual integration in typical and impaired readers at the critical developmental stage of adolescence. Congruent and incongruent audiovisual as well as unimodal (visual only and auditory only) material was presented. Audiovisual presentations were single letters and three-letter (consonant-vowel-consonant) stimuli accompanied by matching or mismatching speech sounds. Three-letter stimuli exhibited fast phonetic transitions as in real-life language processing and reading. Congruency effects, i.e. different brain responses to congruent and incongruent stimuli were taken as an indicator of audiovisual integration at a phonetic level (grapho-phonological conversion). Comparisons of unimodal and audiovisual stimuli revealed basic, more sensory aspects of audiovisual integration. By means of these two criteria of audiovisual integration, the generalizability of audiovisual deficits in dyslexia was tested. Moreover, it was expected that the more naturalistic three-letter stimuli are superior to single letters in revealing group differences. Electrophysiological and hemodynamic (EEG and fMRI) data were acquired simultaneously in a simple target detection task. Applying the same statistical models to event-related EEG potentials and fMRI responses allowed comparing the effects detected by the two techniques at a descriptive level. Group differences in congruency effects (congruent against incongruent) were observed in regions involved in grapho-phonological processing, including the left inferior frontal and angular gyri and the inferotemporal cortex. Importantly, such differences also emerged in superior temporal key regions. Three-letter stimuli revealed stronger group differences than single letters. No significant differences in basic measures of audiovisual integration emerged. Convergence of hemodynamic and electrophysiological signals appeared to be limited and mainly occurred for highly significant and large effects in visual cortices. The findings suggest efficient superior temporal tuning to audiovisual congruency in controls. In impaired readers, however, grapho-phonological conversion is effortful and inefficient, although basic audiovisual mechanisms seem intact. This unprecedented demonstration of audiovisual deficits in adolescent dyslexics provides critical evidence that the phonological deficit might be explained by impaired audiovisual integration at a phonetic level, especially for naturalistic and word-like stimulation. Copyright © 2014 Elsevier Ltd. All rights reserved.
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Orthography affects second language speech: Double letters and geminate production in English.
Bassetti, Bene
2017-11-01
Second languages (L2s) are often learned through spoken and written input, and L2 orthographic forms (spellings) can lead to non-native-like pronunciation. The present study investigated whether orthography can lead experienced learners of English L2 to make a phonological contrast in their speech production that does not exist in English. Double consonants represent geminate (long) consonants in Italian but not in English. In Experiment 1, native English speakers and English L2 speakers (Italians) were asked to read aloud English words spelled with a single or double target consonant letter, and consonant duration was compared. The English L2 speakers produced the same consonant as shorter when it was spelled with a single letter, and longer when spelled with a double letter. Spelling did not affect consonant duration in native English speakers. In Experiment 2, effects of orthographic input were investigated by comparing 2 groups of English L2 speakers (Italians) performing a delayed word repetition task with or without orthographic input; the same orthographic effects were found in both groups. These results provide arguably the first evidence that L2 orthographic forms can lead experienced L2 speakers to make a contrast in their L2 production that does not exist in the language. The effect arises because L2 speakers are affected by the interaction between the L2 orthographic form (number of letters), and their native orthography-phonology mappings, whereby double consonant letters represent geminate consonants. These results have important implications for future studies investigating the effects of orthography on native phonology and for L2 phonological development models. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
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Towards a Universal Model of Reading
Frost, Ram
2013-01-01
In the last decade, reading research has seen a paradigmatic shift. A new wave of computational models of orthographic processing that offer various forms of noisy position or context-sensitive coding, have revolutionized the field of visual word recognition. The influx of such models stems mainly from consistent findings, coming mostly from European languages, regarding an apparent insensitivity of skilled readers to letter-order. Underlying the current revolution is the theoretical assumption that the insensitivity of readers to letter order reflects the special way in which the human brain encodes the position of letters in printed words. The present paper discusses the theoretical shortcomings and misconceptions of this approach to visual word recognition. A systematic review of data obtained from a variety of languages demonstrates that letter-order insensitivity is not a general property of the cognitive system, neither it is a property of the brain in encoding letters. Rather, it is a variant and idiosyncratic characteristic of some languages, mostly European, reflecting a strategy of optimizing encoding resources, given the specific structure of words. Since the main goal of reading research is to develop theories that describe the fundamental and invariant phenomena of reading across orthographies, an alternative approach to model visual word recognition is offered. The dimensions of a possible universal model of reading, which outlines the common cognitive operations involved in orthographic processing in all writing systems, are discussed. PMID:22929057
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Towards a universal model of reading.
Frost, Ram
2012-10-01
In the last decade, reading research has seen a paradigmatic shift. A new wave of computational models of orthographic processing that offer various forms of noisy position or context-sensitive coding have revolutionized the field of visual word recognition. The influx of such models stems mainly from consistent findings, coming mostly from European languages, regarding an apparent insensitivity of skilled readers to letter order. Underlying the current revolution is the theoretical assumption that the insensitivity of readers to letter order reflects the special way in which the human brain encodes the position of letters in printed words. The present article discusses the theoretical shortcomings and misconceptions of this approach to visual word recognition. A systematic review of data obtained from a variety of languages demonstrates that letter-order insensitivity is neither a general property of the cognitive system nor a property of the brain in encoding letters. Rather, it is a variant and idiosyncratic characteristic of some languages, mostly European, reflecting a strategy of optimizing encoding resources, given the specific structure of words. Since the main goal of reading research is to develop theories that describe the fundamental and invariant phenomena of reading across orthographies, an alternative approach to model visual word recognition is offered. The dimensions of a possible universal model of reading, which outlines the common cognitive operations involved in orthographic processing in all writing systems, are discussed.
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Weight bias in graduate school admissions.
Burmeister, Jacob M; Kiefner, Allison E; Carels, Robert A; Musher-Eizenman, Dara R
2013-05-01
Whether weight bias occurs in the graduate school admissions process is explored here. Specifically, we examined whether body mass index (BMI) was related to letter of recommendation quality and the number of admissions offers applicants received after attending in-person interviews. Participants were 97 applicants to a psychology graduate program at a large university in the United States. They reported height, weight, and information about their applications to psychology graduate programs. Participants' letters of recommendation were coded for positive and negative statements as well as overall quality. Higher BMI significantly predicted fewer post-interview offers of admission into psychology graduate programs. Results also suggest this relationship is stronger for female applicants. BMI was not related to overall quality or the number of stereotypically weight-related adjectives in letters of recommendation. Surprisingly, higher BMI was related to more positive adjectives in letters. The first evidence that individuals interviewing applicants to graduate programs may systematically favor thinner applicants is provided here. A conscious or unconscious bias against applicants with extra body weight is a plausible explanation. Stereotype threat and social identity threat are also discussed as explanations for the relationship between BMI and interview success. Copyright © 2012 The Obesity Society.
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VARiD: a variation detection framework for color-space and letter-space platforms.
Dalca, Adrian V; Rumble, Stephen M; Levy, Samuel; Brudno, Michael
2010-06-15
High-throughput sequencing (HTS) technologies are transforming the study of genomic variation. The various HTS technologies have different sequencing biases and error rates, and while most HTS technologies sequence the residues of the genome directly, generating base calls for each position, the Applied Biosystem's SOLiD platform generates dibase-coded (color space) sequences. While combining data from the various platforms should increase the accuracy of variation detection, to date there are only a few tools that can identify variants from color space data, and none that can analyze color space and regular (letter space) data together. We present VARiD--a probabilistic method for variation detection from both letter- and color-space reads simultaneously. VARiD is based on a hidden Markov model and uses the forward-backward algorithm to accurately identify heterozygous, homozygous and tri-allelic SNPs, as well as micro-indels. Our analysis shows that VARiD performs better than the AB SOLiD toolset at detecting variants from color-space data alone, and improves the calls dramatically when letter- and color-space reads are combined. The toolset is freely available at http://compbio.cs.utoronto.ca/varid.
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Child's Letter to President John F. Kennedy about Physical Fitness
ERIC Educational Resources Information Center
McNatt, Missy
2009-01-01
On March 3, 1963, nine-year-old Jack Chase of Torrance, California, wrote a letter to President John F. Kennedy. In his single-page note, featured in this article, Jack described his plans for staying physically fit. He said he would walk to school, the store, and the library "because I know a strong boy makes a strong man and a strong man makes a…
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Resource Letter: LBOT-1: Laser-based optical tweezers
Lang, Matthew J.; Block, Steven M.
2006-01-01
This Resource Letter provides a guide to the literature on optical tweezers, also known as laser-based, gradient-force optical traps. Journal articles and books are cited for the following main topics: general papers on optical tweezers, trapping instrument design, optical detection methods, optical trapping theory, mechanical measurements, single molecule studies, and sections on biological motors, cellular measurements and additional applications of optical tweezers. PMID:16971965
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Resource Letter: LBOT-1: Laser-based optical tweezers.
Lang, Matthew J; Block, Steven M
2003-03-01
This Resource Letter provides a guide to the literature on optical tweezers, also known as laser-based, gradient-force optical traps. Journal articles and books are cited for the following main topics: general papers on optical tweezers, trapping instrument design, optical detection methods, optical trapping theory, mechanical measurements, single molecule studies, and sections on biological motors, cellular measurements and additional applications of optical tweezers.
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76 FR 74704 - Folded Self-Mailers and Unenveloped Mailpieces
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-01
....14.8 or 3.14.9b through 3.14.9f. 3.15.2 Letter-Size Mailpieces With Tear-Off Strips When letter-size mailpieces have tear-off strips on the leading and/or trailing edge, any unfolded edges must be sealed with.... b. Tear-off strips may be up to \\9/16\\ inch (0.5625) wide. c. Tear lines (single lines of...
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Using Arden Syntax for the Generation of Intelligent Intensive Care Discharge Letters.
Kraus, Stefan; Castellanos, Ixchel; Albermann, Matthias; Schuettler, Christina; Prokosch, Hans-Ulrich; Staudigel, Martin; Toddenroth, Dennis
2016-01-01
Discharge letters are an important means of communication between physicians and nurses from intensive care units and their colleagues from normal wards. The patient data management system (PDMS) used at our local intensive care units provides an export tool to create discharge letters by inserting data items from electronic medical records into predefined templates. Local intensivists criticized the limitations of this tool regarding the identification and the further processing of clinically relevant data items for a flexible creation of discharge letters. As our PDMS supports Arden Syntax, and the demanded functionalities are well within the scope of this standard, we set out to investigate the suitability of Arden Syntax for the generation of discharge letters. To provide an easy-to-understand facility for integrating data items into document templates, we created an Arden Syntax interface function which replaces the names of previously defined variables with their content in a way that permits arbitrary custom formatting by clinical users. Our approach facilitates the creation of flexible text sections by conditional statements, as well as the integration of arbitrary HTML code and dynamically generated graphs. The resulting prototype enables clinical users to apply the full set of Arden Syntax language constructs to identify and process relevant data items in a way that far exceeds the capabilities of the PDMS export tool. The generation of discharge letters is an uncommon area of application for Arden Syntax, considerably differing from its original purpose. However, we found our prototype well suited for this task and plan to evaluate it in clinical production after the next major release change of our PDMS.
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78 FR 20334 - Changes in Flood Hazard Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-04
... a Letter of Map Revision (LOMR), in accordance with Title 44, Part 65 of the Code of Federal... in a newspaper of local circulation, any person has ninety (90) days in which to request through the........... 060299 areas San Joaquin Vogel, Chairman, Public Works Docs/12-09-2566P- County (12-09- San Joaquin...
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Building Needs for the Handicapped.
ERIC Educational Resources Information Center
Windham Southeast Supervisory Union, Brattleboro, VT.
Listed in the document are specific building needs for the handicapped. It is explained that the detailed survey forms can be used to determine building accessibility for a wide range of handicapping conditions. Survey information includes the specific building need (e.g. 12 foot wide parking space) and the letter code for affected function. Space…
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UCC2B: The Impact on Information Professionals.
ERIC Educational Resources Information Center
Ebbinghouse, Carol
1998-01-01
Discusses the impact of the Uniform Commercial Code (UCC) Article 2B, dealing with licenses of information and software contracts, on information professionals. Mass market licenses, copyrights, standard form contracts, and impact on first sale are examined. A sidebar lists key World Wide Web sites and includes a sample letter of concern. (LRW)
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The Use of Final-Letter Braille Contractions: A Case Study
ERIC Educational Resources Information Center
Tallon, Emily M.; Herzberg, Tina S.
2013-01-01
Louis Braille developed a six-dot braille code in the early 1800s, thus creating an effective way for persons who are visually impaired to communicate through reading and writing (Holbrook, D'Andrea, & Sanford, 2011). Students with visual impairments require braille instruction from teachers of students with visual impairments, who are responsible…
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-03
... type of switch software) to provide payphone specific coding digits for per-call compensation. The... Information; [cir] RF Exposure Information; [cir] Operational Description; [cir] Cover Letters; [cir] Software Defined Radio/Cognitive Radio Files In general, an applicant's submission is as follows: (a) FCC Form 731...
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78 FR 32673 - Changes in Flood Hazard Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-31
... a Letter of Map Revision (LOMR), in accordance with Title 44, Part 65 of the Code of Federal Regulations (44 CFR Part 65). The LOMR will be used by insurance agents and others to calculate appropriate... Act of 1968, 42 U.S.C. 4001 et seq., and with 44 CFR Part 65. [[Page 32674
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ERIC Educational Resources Information Center
Wang, Ling; Blackwell, Aleka Akoyunoglou
2015-01-01
Native speakers of alphabetic languages, which use letters governed by grapheme-phoneme correspondence rules, often find it particularly challenging to learn a logographic language whose writing system employs symbols with no direct sound-to-spelling connection but links to the visual and semantic information. The visuospatial properties of…
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49 CFR 381.210 - How do I request a waiver?
Code of Federal Regulations, 2010 CFR
2010-10-01
... a written request (for example, a typed or handwritten (printed) letter), which includes all of the...) Principal place of business for the motor carrier or other entity (street address, city, State, and zip code... written statement that: (1) Describes the unique, non-emergency event for which the waiver would be used...
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40 CFR 147.1350 - State-administered programs-Class II wells.
Code of Federal Regulations, 2014 CFR
2014-07-01
...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (1) Montana...) Letter dated March 8, 1996, from MBOGC independent counsel to USEPA, Region VIII; “Re: EPA comments of... Administrator of the MBOGC and the attached proposed replacement language for the MOA; “Re: Responses to EPA...
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40 CFR 147.300 - State-administered program-Class II wells.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr... Colorado Assistant Attorney General to the Acting Regional Counsel, EPA Region VIII, “Re: Class II Well...) Letter from Colorado Assistant Attorney General to the Acting Regional Counsel, EPA Region VIII, “Re...
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40 CFR 147.1350 - State-administered programs-Class II wells.
Code of Federal Regulations, 2012 CFR
2012-07-01
...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (1) Montana...) Letter dated March 8, 1996, from MBOGC independent counsel to USEPA, Region VIII; “Re: EPA comments of... Administrator of the MBOGC and the attached proposed replacement language for the MOA; “Re: Responses to EPA...
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40 CFR 147.300 - State-administered program-Class II wells.
Code of Federal Regulations, 2014 CFR
2014-07-01
..., call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr... Colorado Assistant Attorney General to the Acting Regional Counsel, EPA Region VIII, “Re: Class II Well...) Letter from Colorado Assistant Attorney General to the Acting Regional Counsel, EPA Region VIII, “Re...
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40 CFR 147.1350 - State-administered programs-Class II wells.
Code of Federal Regulations, 2010 CFR
2010-07-01
...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (1) Montana...) Letter dated March 8, 1996, from MBOGC independent counsel to USEPA, Region VIII; “Re: EPA comments of... Administrator of the MBOGC and the attached proposed replacement language for the MOA; “Re: Responses to EPA...
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40 CFR 147.1350 - State-administered programs-Class II wells.
Code of Federal Regulations, 2013 CFR
2013-07-01
...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (1) Montana...) Letter dated March 8, 1996, from MBOGC independent counsel to USEPA, Region VIII; “Re: EPA comments of... Administrator of the MBOGC and the attached proposed replacement language for the MOA; “Re: Responses to EPA...
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40 CFR 147.300 - State-administered program-Class II wells.
Code of Federal Regulations, 2013 CFR
2013-07-01
..., call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr... Colorado Assistant Attorney General to the Acting Regional Counsel, EPA Region VIII, “Re: Class II Well...) Letter from Colorado Assistant Attorney General to the Acting Regional Counsel, EPA Region VIII, “Re...
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40 CFR 147.300 - State-administered program-Class II wells.
Code of Federal Regulations, 2012 CFR
2012-07-01
..., call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr... Colorado Assistant Attorney General to the Acting Regional Counsel, EPA Region VIII, “Re: Class II Well...) Letter from Colorado Assistant Attorney General to the Acting Regional Counsel, EPA Region VIII, “Re...
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40 CFR 147.1350 - State-administered programs-Class II wells.
Code of Federal Regulations, 2011 CFR
2011-07-01
...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (1) Montana...) Letter dated March 8, 1996, from MBOGC independent counsel to USEPA, Region VIII; “Re: EPA comments of... Administrator of the MBOGC and the attached proposed replacement language for the MOA; “Re: Responses to EPA...
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77 FR 6171 - Petition for Waiver of Compliance
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-07
...] Petition for Waiver of Compliance In accordance with Part 211 of Title 49 of the Code of Federal... request for a waiver of compliance from certain requirements of its safety standards. In a letter dated... permanent waiver of compliance for one switching locomotive (HVRM 11) from the requirements of 49 CFR part...
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Cardiac ultrasonography over 4G wireless networks using a tele-operated robot
Panayides, Andreas S.; Jossif, Antonis P.; Christoforou, Eftychios G.; Vieyres, Pierre; Novales, Cyril; Voskarides, Sotos; Pattichis, Constantinos S.
2016-01-01
This Letter proposes an end-to-end mobile tele-echography platform using a portable robot for remote cardiac ultrasonography. Performance evaluation investigates the capacity of long-term evolution (LTE) wireless networks to facilitate responsive robot tele-manipulation and real-time ultrasound video streaming that qualifies for clinical practice. Within this context, a thorough video coding standards comparison for cardiac ultrasound applications is performed, using a data set of ten ultrasound videos. Both objective and subjective (clinical) video quality assessment demonstrate that H.264/AVC and high efficiency video coding standards can achieve diagnostically-lossless video quality at bitrates well within the LTE supported data rates. Most importantly, reduced latencies experienced throughout the live tele-echography sessions allow the medical expert to remotely operate the robot in a responsive manner, using the wirelessly communicated cardiac ultrasound video to reach a diagnosis. Based on preliminary results documented in this Letter, the proposed robotised tele-echography platform can provide for reliable, remote diagnosis, achieving comparable quality of experience levels with in-hospital ultrasound examinations. PMID:27733929
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Mid-Infrared Photonic Devices Fabricated by Ultrafast Laser Inscription
2016-07-01
active and passive photonic devices in single crystal, ceramic and glass substrates. This range of devices span applications such as: astrophysics [16...waveguide has been published this year in Applied Physics Letters. Reference: Macdonald, J.R., et al., Compact mid-infrared Cr:ZnSe channel...waveguide laser. Applied Physics Letters, 2013. 102(16): p. 161110. High efficiency circular cladding WG laser The initial demonstration of square double
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Daffner, Kirk R; Alperin, Brittany R; Mott, Katherine K; Holcomb, Phillip J
2014-01-22
Older adults exhibit diminished ability to inhibit the processing of visual stimuli that are supposed to be ignored. The extent to which age-related changes in early visual processing contribute to impairments in selective attention remains to be determined. Here, 103 adults, 18-85 years of age, completed a color selective attention task in which they were asked to attend to a specified color and respond to designated target letters. An optimal approach would be to initially filter according to color and then process letter forms in the attend color to identify targets. An asymmetric N170 ERP component (larger amplitude over left posterior hemisphere sites) was used as a marker of the early automatic processing of letter forms. Young and middle-aged adults did not generate an asymmetric N170 component. In contrast, young-old and old-old adults produced a larger N170 over the left hemisphere. Furthermore, older adults generated a larger N170 to letter than nonletter stimuli over the left, but not right hemisphere. More asymmetric N170 responses predicted greater allocation of late selection resources to target letters in the ignore color, as indexed by P3b amplitude. These results suggest that unlike their younger counterparts, older adults automatically process stimuli as letters early in the selection process, when it would be more efficient to attend to color only. The inability to ignore letters early in the processing stream helps explain the age-related increase in subsequent processing of target letter forms presented in the ignore color.
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The sugar code: Why glycans are so important.
Gabius, Hans-Joachim
2018-02-01
The cell surface is the platform for presentation of biochemical signals that are required for intercellular communication. Their profile necessarily needs to be responsive to internal and external factors in a highly dynamic manner. The structural features of the signals must meet the criterion of high-density information coding in a minimum of space. Thus, only biomolecules that can generate many different oligomers ('words') from few building blocks ('letters') qualify to meet this challenge. Examining the respective properties of common biocompounds that form natural oligo- and polymers comparatively, starting with nucleotides and amino acids (the first and second alphabets of life), comes up with sugars as clear frontrunner. The enzymatic machinery for the biosynthesis of sugar chains can indeed link monosaccharides, the letters of the third alphabet of life, in a manner to reach an unsurpassed number of oligomers (complex carbohydrates or glycans). Fittingly, the resulting glycome of a cell can be likened to a fingerprint. Conjugates of glycans with proteins and sphingolipids (glycoproteins and glycolipids) are ubiquitous in Nature. This implies a broad (patho)physiologic significance. By looking at the signals, at the writers and the erasers of this information as well as its readers and ensuing consequences, this review intends to introduce a broad readership to the principles of the concept of the sugar code. Copyright © 2017 Elsevier B.V. All rights reserved.
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Viewing hybrid systems as products of control systems and automata
NASA Technical Reports Server (NTRS)
Grossman, R. L.; Larson, R. G.
1992-01-01
The purpose of this note is to show how hybrid systems may be modeled as products of nonlinear control systems and finite state automata. By a hybrid system, we mean a network of consisting of continuous, nonlinear control system connected to discrete, finite state automata. Our point of view is that the automata switches between the control systems, and that this switching is a function of the discrete input symbols or letters that it receives. We show how a nonlinear control system may be viewed as a pair consisting of a bialgebra of operators coding the dynamics, and an algebra of observations coding the state space. We also show that a finite automata has a similar representation. A hybrid system is then modeled by taking suitable products of the bialgebras coding the dynamics and the observation algebras coding the state spaces.
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2015-01-15
Shi, University of Texas - Austin Thermal and Thermoelectric Properties and Applications of Two-Dimensional Materials beyond Graphene 11:45 – 1:15 pm...M., et al., Large and tunable photo- thermoelectric effect in single-layer MoS2, Nano Letters (2013) [4] Castellanos-Gomez, A., et al., Isolation...phosphorus field- effect transistors. Nano Letters (2014) [6] Buscema M., et al., Photovoltaic effect in few-layer black phosphorus PN junctions
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ERIC Educational Resources Information Center
Suortti, Outi; Lipponen, Lasse
2014-01-01
The present study is the first part of a longitudinal research project investigating whether children become more aware of phonemes or rhyming when they learn letters or letter sounds or even begin to read, and if so how. For the present paper, the phonological awareness of young children aged 2-6 years was analyzed, particularly their auditory…
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1989-02-01
Doctor of Philosophy in the Department of Experimental and Clinical Psychology in the Graduate School of the University of Alabama. Ii. Table of...6 In contrast to this popular single buffer account, other authors have offered more complex descriptions of the mechanisms involved in the processing...experiment exploring sex differences in retention of verbal and spatial information in short-term memory. Males remembered letter identity and letter
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50 CFR 23.74 - How can I trade internationally in personal sport-hunted trophies?
Code of Federal Regulations, 2014 CFR
2014-10-01
... certificate must contain all the information that is given on the tag. (2) African elephant (Loxodonta... sport-hunted trophies of African elephant. The trophy ivory must be legibly marked by means of punch... corresponding two-letter ISO country code; the last two digits of the year in which the elephant was harvested...
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Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 19 2010-07-01 2010-07-01 false Sampling Plans for Selective Enforcement Auditing of Light-Duty Vehicles XI Appendix XI to Part 86 Protection of Environment ENVIRONMENTAL... Enforcement Auditing of Light-Duty Vehicles 40% AQL Table 1—Sampling Plan Code Letter Annual sales of...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-22
... principal author of these regulations is Nathan Rosen of the Office of Associate Chief Counsel (Procedure... with a 30-day letter that proposes to disallow the charitable contribution deduction resulting in a... contribution was paid during the tax year. Therefore, this deduction is not allowable.'' The information in the...
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40 CFR 147.2551 - State-administered program-Class II wells.
Code of Federal Regulations, 2012 CFR
2012-07-01
..., call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr..., “Re: Application for Primacy in the Regulation of Class II Injection Wells,” March 8, 1982; (5) Letter from State Oil and Gas Supervisor, Wyoming Oil and Gas Conservation Commission, to EPA Region VIII, “Re...
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40 CFR 147.2551 - State-administered program-Class II wells.
Code of Federal Regulations, 2010 CFR
2010-07-01
..., call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr..., “Re: Application for Primacy in the Regulation of Class II Injection Wells,” March 8, 1982; (5) Letter from State Oil and Gas Supervisor, Wyoming Oil and Gas Conservation Commission, to EPA Region VIII, “Re...
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40 CFR 147.2551 - State-administered program-Class II wells.
Code of Federal Regulations, 2013 CFR
2013-07-01
..., call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr..., “Re: Application for Primacy in the Regulation of Class II Injection Wells,” March 8, 1982; (5) Letter from State Oil and Gas Supervisor, Wyoming Oil and Gas Conservation Commission, to EPA Region VIII, “Re...
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40 CFR 147.2551 - State-administered program-Class II wells.
Code of Federal Regulations, 2014 CFR
2014-07-01
..., call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr..., “Re: Application for Primacy in the Regulation of Class II Injection Wells,” March 8, 1982; (5) Letter from State Oil and Gas Supervisor, Wyoming Oil and Gas Conservation Commission, to EPA Region VIII, “Re...
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40 CFR 147.2551 - State-administered program-Class II wells.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr..., “Re: Application for Primacy in the Regulation of Class II Injection Wells,” March 8, 1982; (5) Letter from State Oil and Gas Supervisor, Wyoming Oil and Gas Conservation Commission, to EPA Region VIII, “Re...
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Nudging guideline-concordant antibiotic prescribing: a randomized clinical trial.
Meeker, Daniella; Knight, Tara K; Friedberg, Mark W; Linder, Jeffrey A; Goldstein, Noah J; Fox, Craig R; Rothfeld, Alan; Diaz, Guillermo; Doctor, Jason N
2014-03-01
"Nudges" that influence decision making through subtle cognitive mechanisms have been shown to be highly effective in a wide range of applications, but there have been few experiments to improve clinical practice. To investigate the use of a behavioral "nudge" based on the principle of public commitment in encouraging the judicious use of antibiotics for acute respiratory infections (ARIs). Randomized clinical trial in 5 outpatient primary care clinics. A total of 954 adults had ARI visits during the study timeframe: 449 patients were treated by clinicians randomized to the posted commitment letter (335 in the baseline period, 114 in the intervention period); 505 patients were treated by clinicians randomized to standard practice control (384 baseline, 121 intervention). The intervention consisted of displaying poster-sized commitment letters in examination rooms for 12 weeks. These letters, featuring clinician photographs and signatures, stated their commitment to avoid inappropriate antibiotic prescribing for ARIs. Antibiotic prescribing rates for antibiotic-inappropriate ARI diagnoses in baseline and intervention periods, adjusted for patient age, sex, and insurance status. Baseline rates were 43.5% and 42.8% for control and poster, respectively. During the intervention period, inappropriate prescribing rates increased to 52.7% for controls but decreased to 33.7% in the posted commitment letter condition. Controlling for baseline prescribing rates, we found that the posted commitment letter resulted in a 19.7 absolute percentage reduction in inappropriate antibiotic prescribing rate relative to control (P = .02). There was no evidence of diagnostic coding shift, and rates of appropriate antibiotic prescriptions did not diminish over time. Displaying poster-sized commitment letters in examination rooms decreased inappropriate antibiotic prescribing for ARIs. The effect of this simple, low-cost intervention is comparable in magnitude to costlier, more intensive quality-improvement efforts. clinicaltrials.gov identifier: NCT01767064.
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Kerzel, Dirk; Gauch, Angélique; Buetti, Simona
2010-10-01
Improvements of perceptual performance following the presentation of peripheral cues have been ascribed to accelerated accrual of information, enhanced contrast perception, and decision bias. We investigated effects of peripheral cues on the perception of Gabor and letter stimuli. Non-predictive, peripheral cues improved perceptual accuracy when the stimuli were masked. In contrast, peripheral cues degraded perception of low-contrast letters and did not affect the perception of low-contrast Gabors. The results suggest that involuntary attention accelerates accrual of information but are not entirely consistent with the idea that involuntary attention enhances subjective contrast. Rather, peripheral cues may cause crowding with single letter targets of low contrast. Further, we investigated the effect of the amount of uncertainty on involuntary attention. Cueing effects were (initially) larger when there were more possible target locations. In addition, cueing effects were larger when error feedback was absent and observers had no knowledge of results. Despite these strategic factors, location uncertainty was not sufficient to produce cueing effects, showing that location uncertainty paired with non-predictive cues reveals perceptual and not (only) decisional processes.
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Philosophical Intelligence: Letters, Print, and Experiment during Napoleon's Continental Blockade.
Watts, Iain P
2015-12-01
This essay investigates scientific exchanges between Britain and France from 1806 to 1814, at the height of the Napoleonic Wars. It argues for a picture of scientific communication that sees letters and printed texts not as separate media worlds, but as interconnected bearers of time-critical information within a single system of intelligence gathering and experimental practice. During this period, Napoleon Bonaparte's Continental System blockade severed most links between Britain and continental Europe, yet scientific communications continued--particularly on electrochemistry, a subject of fierce rivalry between Britain and France. The essay traces these exchanges using the archive of a key go-between, the English man of science Sir Charles Blagden. The first two sections look at Blagden's letter-writing operation, reconstructing how he harnessed connections with neutral American diplomats, merchants, and the State to get scientific intelligence between London and Paris. The third section, following Blagden's words from Britain to France to America, looks at how information in letters cross-fertilized with information in print. The final section considers how letters and print were used together to solve the difficult practical problem of replicating experiments across the blockade.
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Known-plaintext attack on a joint transform correlator encrypting system.
Barrera, John Fredy; Vargas, Carlos; Tebaldi, Myrian; Torroba, Roberto; Bolognini, Nestor
2010-11-01
We demonstrate in this Letter that a joint transform correlator shows vulnerability to known-plaintext attacks. An unauthorized user, who intercepts both an object and its encrypted version, can obtain the security key code mask. In this contribution, we conduct a hybrid heuristic attack scheme merge to a Gerchberg-Saxton routine to estimate the encrypting key to decode different ciphertexts encrypted with that same key. We also analyze the success of this attack for different pairs of plaintext-ciphertext used to get the encrypting code. We present simulation results for the decrypting procedure to demonstrate the validity of our analysis.
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Zhang, Chenchu; Hu, Yanlei; Du, Wenqiang; Wu, Peichao; Rao, Shenglong; Cai, Ze; Lao, Zhaoxin; Xu, Bing; Ni, Jincheng; Li, Jiawen; Zhao, Gang; Wu, Dong; Chu, Jiaru; Sugioka, Koji
2016-09-13
Rapid integration of high-quality functional devices in microchannels is in highly demand for miniature lab-on-a-chip applications. This paper demonstrates the embellishment of existing microfluidic devices with integrated micropatterns via femtosecond laser MRAF-based holographic patterning (MHP) microfabrication, which proves two-photon polymerization (TPP) based on spatial light modulator (SLM) to be a rapid and powerful technology for chip functionalization. Optimized mixed region amplitude freedom (MRAF) algorithm has been used to generate high-quality shaped focus field. Base on the optimized parameters, a single-exposure approach is developed to fabricate 200 × 200 μm microstructure arrays in less than 240 ms. Moreover, microtraps, QR code and letters are integrated into a microdevice by the advanced method for particles capture and device identification. These results indicate that such a holographic laser embellishment of microfluidic devices is simple, flexible and easy to access, which has great potential in lab-on-a-chip applications of biological culture, chemical analyses and optofluidic devices.
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NASA Astrophysics Data System (ADS)
Zhang, Chenchu; Hu, Yanlei; Du, Wenqiang; Wu, Peichao; Rao, Shenglong; Cai, Ze; Lao, Zhaoxin; Xu, Bing; Ni, Jincheng; Li, Jiawen; Zhao, Gang; Wu, Dong; Chu, Jiaru; Sugioka, Koji
2016-09-01
Rapid integration of high-quality functional devices in microchannels is in highly demand for miniature lab-on-a-chip applications. This paper demonstrates the embellishment of existing microfluidic devices with integrated micropatterns via femtosecond laser MRAF-based holographic patterning (MHP) microfabrication, which proves two-photon polymerization (TPP) based on spatial light modulator (SLM) to be a rapid and powerful technology for chip functionalization. Optimized mixed region amplitude freedom (MRAF) algorithm has been used to generate high-quality shaped focus field. Base on the optimized parameters, a single-exposure approach is developed to fabricate 200 × 200 μm microstructure arrays in less than 240 ms. Moreover, microtraps, QR code and letters are integrated into a microdevice by the advanced method for particles capture and device identification. These results indicate that such a holographic laser embellishment of microfluidic devices is simple, flexible and easy to access, which has great potential in lab-on-a-chip applications of biological culture, chemical analyses and optofluidic devices.
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Sawamura, Jitsuki; Morishita, Shigeru; Ishigooka, Jun
2014-05-07
Previously, we suggested prototypal models that describe some clinical states based on group postulates. Here, we demonstrate a group/category theory-like model for molecular/genetic biology as an alternative application of our previous model. Specifically, we focus on deoxyribonucleic acid (DNA) base sequences. We construct a wallpaper pattern based on a five-letter cruciform motif with letters C, A, T, G, and E. Whereas the first four letters represent the standard DNA bases, the fifth is introduced for ease in formulating group operations that reproduce insertions and deletions of DNA base sequences. A basic group Z5 = {r, u, d, l, n} of operations is defined for the wallpaper pattern, with which a sequence of points can be generated corresponding to changes of a base in a DNA sequence by following the orbit of a point of the pattern under operations in group Z5. Other manipulations of DNA sequence can be treated using a vector-like notation 'Dj' corresponding to a DNA sequence but based on the five-letter base set; also, 'Dj's are expressed graphically. Insertions and deletions of a series of letters 'E' are admitted to assist in describing DNA recombination. Likewise, a vector-like notation Rj can be constructed for sequences of ribonucleic acid (RNA). The wallpaper group B = {Z5×∞, ●} (an ∞-fold Cartesian product of Z5) acts on Dj (or Rj) yielding changes to Dj (or Rj) denoted by 'Dj◦B(j→k) = Dk' (or 'Rj◦B(j→k) = Rk'). Based on the operations of this group, two types of groups-a modulo 5 linear group and a rotational group over the Gaussian plane, acting on the five bases-are linked as parts of the wallpaper group for broader applications. As a result, changes, insertions/deletions and DNA (RNA) recombination (partial/total conversion) are described. As an exploratory study, a notation for the canonical "central dogma" via a category theory-like way is presented for future developments. Despite the large incompleteness of our methodology, there is fertile ground to consider a symmetry model for genetic coding based on our specific wallpaper group. A more integrated formulation containing "central dogma" for future molecular/genetic biology remains to be explored.
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Awadh, Faris H R; Phénix, Thierry; Antzaka, Alexia; Lallier, Marie; Carreiras, Manuel; Valdois, Sylviane
2016-01-01
In delineating the amount of orthographic information that can be processed in parallel during a single fixation, the visual attention (VA) span acts as a key component of the reading system. Previous studies focused on the contribution of VA span to normal and pathological reading in monolingual and bilingual children from different European languages, without direct cross-language comparison. In the current paper, we explored modulations of VA span abilities in three languages -French, Spanish, and Arabic- that differ in transparency, reading direction and writing systems. The participants were skilled adult readers who were native speakers of French, Spanish or Arabic. They were administered tasks of global and partial letter report, single letter identification and text reading. Their VA span abilities were assessed using tasks that require the processing of briefly presented five consonant strings (e.g., R S H F T). All five consonants had to be reported in global report but a single cued letter in partial report. Results showed that VA span was reduced in Arabic readers as compared to French or Spanish readers who otherwise show a similar high performance in the two report tasks. The analysis of VA span response patterns in global report showed a left-right asymmetry in all three languages. A leftward letter advantage was found in French and Spanish but a rightward advantage in Arabic. The response patterns were symmetric in partial report, regardless of the language. Last, a significant relationship was found between VA span abilities and reading speed but only for French. The overall findings suggest that the size of VA span, the shape of VA span response patterns and the VA Span-reading relationship are modulated by language-specific features.
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Awadh, Faris H. R.; Phénix, Thierry; Antzaka, Alexia; Lallier, Marie; Carreiras, Manuel; Valdois, Sylviane
2016-01-01
In delineating the amount of orthographic information that can be processed in parallel during a single fixation, the visual attention (VA) span acts as a key component of the reading system. Previous studies focused on the contribution of VA span to normal and pathological reading in monolingual and bilingual children from different European languages, without direct cross-language comparison. In the current paper, we explored modulations of VA span abilities in three languages –French, Spanish, and Arabic– that differ in transparency, reading direction and writing systems. The participants were skilled adult readers who were native speakers of French, Spanish or Arabic. They were administered tasks of global and partial letter report, single letter identification and text reading. Their VA span abilities were assessed using tasks that require the processing of briefly presented five consonant strings (e.g., R S H F T). All five consonants had to be reported in global report but a single cued letter in partial report. Results showed that VA span was reduced in Arabic readers as compared to French or Spanish readers who otherwise show a similar high performance in the two report tasks. The analysis of VA span response patterns in global report showed a left-right asymmetry in all three languages. A leftward letter advantage was found in French and Spanish but a rightward advantage in Arabic. The response patterns were symmetric in partial report, regardless of the language. Last, a significant relationship was found between VA span abilities and reading speed but only for French. The overall findings suggest that the size of VA span, the shape of VA span response patterns and the VA Span-reading relationship are modulated by language-specific features. PMID:27014125
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Effect of stimulus configuration on crowding in strabismic amblyopia.
Norgett, Yvonne; Siderov, John
2017-11-01
Foveal vision in strabismic amblyopia can show increased levels of crowding, akin to typical peripheral vision. Target-flanker similarity and visual-acuity test configuration may cause the magnitude of crowding to vary in strabismic amblyopia. We used custom-designed visual acuity tests to investigate crowding in observers with strabismic amblyopia. LogMAR was measured monocularly in both eyes of 11 adults with strabismic or mixed strabismic/anisometropic amblyopia using custom-designed letter tests. The tests used single-letter and linear formats with either bar or letter flankers to introduce crowding. Tests were presented monocularly on a high-resolution display at a test distance of 4 m, using standardized instructions. For each condition, five letters of each size were shown; testing continued until three letters of a given size were named incorrectly. Uncrowded logMAR was subtracted from logMAR in each of the crowded tests to highlight the crowding effect. Repeated-measures ANOVA showed that letter flankers and linear presentation individually resulted in poorer performance in the amblyopic eyes (respectively, mean normalized logMAR = 0.29, SE = 0.07, mean normalized logMAR = 0.27, SE = 0.07; p < 0.05) and together had an additive effect (mean = 0.42, SE = 0.09, p < 0.001). There was no difference across the tests in the fellow eyes (p > 0.05). Both linear presentation and letter rather than bar flankers increase crowding in the amblyopic eyes of people with strabismic amblyopia. These results suggest the influence of more than one mechanism contributing to crowding in linear visual-acuity charts with letter flankers.
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Impact of referral letters on scheduling of hospital appointments: a randomised control trial.
Jiwa, Moyez; Meng, Xingqiong; O'Shea, Carolyn; Magin, Parker; Dadich, Ann; Pillai, Vinita
2014-07-01
Communication is essential for triage, but intervention trials to improve it are scarce. Referral Writer (RW), a referral letter software program, enables documentation of clinical data and extracts relevant patient details from clinical software. To evaluate whether specialists are more confident about scheduling appointments when they receive more information in referral letters. Single-blind, parallel-groups, controlled design with a 1:1 randomisation. Australian GPs watched video vignettes virtually. GPs wrote referral letters after watching vignettes of patients with cancer symptoms. Letter content was scored against a benchmark. The proportions of referral letters triagable by a specialist with confidence, and in which the specialist was confident the patient had potentially life-limiting pathology were determined. Categorical outcomes were tested with χ(2) and continuous outcomes with t-tests. A random-effects logistic model assessed the influence of group randomisation (RW versus control), GP demographics, clinical specialty, and specialist referral assessor on specialist confidence in the information provided. The intervention (RW) group referred more patients and scored significantly higher on information relayed (mean difference 21.6 [95% confidence intervals {CI} = 20.1 to 23.2]). There was no difference in the proportion of letters for which specialists were confident they had sufficient information for appointment scheduling (RW 77.7% versus control 80.6%, P = 0.16). In the logistic model, limited agreement among specialists contributed substantially to the observed differences in appointment scheduling (P = 35% [95% CI 16% to 59%]). In isolation, referral letter templates are unlikely to improve the scheduling of specialist appointments, even when more information is relayed. © British Journal of General Practice 2014.
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Characterization of Transient Plasma Ignition Flame Kernel Growth for Varying Inlet Conditions
2009-12-01
unlimited 12b. DISTRIBUTION CODE A 13. ABSTRACT (maximum 200 words) Pulse detonation engines ( PDEs ) have the...Instruments NPS - Naval Postgraduate School PDC - Pulse Detonation Combustor PDE - Pulse Detonation Engine Phi The Greek letter Φ PSIA...produced little to no new chemical propulsion developments; only improvements to existing architectures. The Pulse Detonation Engine ( PDE ) is a
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ERIC Educational Resources Information Center
Commission of the European Communities, Brussels (Belgium).
This document presents an overview of the principal labor market measures taken by the 15 member states of the European Union since the publication of the 1995 overview. In each section, individual countries' actions are discussed separately, with code letters indicating the country name. The following topics are among those discussed in the…
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-13
...\\ See Letter from Stephen Matthews, Senior Associate General Counsel, NASDAQ OMX, dated Jan. 15, 2013... from Jeffrey S. Davis, Vice President and Deputy General Counsel, NASDAQ OMX, dated Feb. 27, 2013. \\10.... O'Neill, Deputy Secretary. [FR Doc. 2013-13999 Filed 6-12-13; 8:45 am] BILLING CODE 8011-01-P ...
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[Respect of patient's dignity in the hospital].
Duguet, A-M
2010-12-01
Every code of ethics of health professionals in France considers the respect of dignity as a fundamental duty. The French 2002 Law on patient rights says that the person has the right to respect of dignity and of private life. After a presentation of the articles of ethics codes regarding dignity, this paper presents recommendations to deliver medical care in situations where dignity might be endangered such as for patients hospitalized in psychiatric services without consent, or for medical examination of prisoners or medical care to vulnerable patients unable to express their will, especially in palliative care or at the end of life. Respect of dignity after death is illustrated by the reflection conducted by the Espace Ethique de l'AP-HP (Paris area hospitals) and in the Chart of the mortuary yard. A survey of the patients' letters of complaint received by the emergency service of the Toulouse University Hospital showed that, in five years, there were 188 letters and 18 pointed out infringements to the dignity of the person. The health professional team is now aware of this obligation, and in the accreditation of the hospitals, the respect of dignity is one of the indicators of the quality of medical care.
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Masked priming effects are modulated by expertise in the script.
Perea, Manuel; Abu Mallouh, Reem; Garcı A-Orza, Javier; Carreiras, Manuel
2011-05-01
In a recent study using a masked priming same-different matching task, Garcı´a-Orza, Perea, and Munoz (2010) found a transposition priming effect for letter strings, digit strings, and symbol strings, but not for strings of pseudoletters (i.e., EPRI-ERPI produced similar response times to the control pair EDBI-ERPI). They argued that the mechanism responsible for position coding in masked priming is not operative with those "objects" whose identity cannot be attained rapidly. To assess this hypothesis, Experiment 1 examined masked priming effects in Arabic for native speakers of Arabic, whereas participants in Experiments 2 and 3 were lower intermediate learners of Arabic and readers with no knowledge of Arabic, respectively. Results showed a masked priming effect only for readers who are familiar with the Arabic script. Furthermore, transposed-letter priming in native speakers of Arabic only occurred when the order of the root letters was kept intact. In Experiments 3-7, we examined why masked repetition priming is absent for readers who are unfamiliar with the Arabic script. We discuss the implications of these findings for models of visual-word recognition.
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A Chemical Alphabet for Macromolecular Communications.
Giannoukos, Stamatios; McGuiness, Daniel Tunç; Marshall, Alan; Smith, Jeremy; Taylor, Stephen
2018-06-08
Molecular communications in macroscale environments is an emerging field of study driven by the intriguing prospect of sending coded information over olfactory networks. For the first time, this article reports two signal modulation techniques (on-off keying-OOK, and concentration shift keying-CSK) which have been used to encode and transmit digital information using odors over distances of 1-4 m. Molecular transmission of digital data was experimentally investigated for the letter "r" with a binary value of 01110010 (ASCII) for a gas stream network channel (up to 4 m) using mass spectrometry (MS) as the main detection-decoding system. The generation and modulation of the chemical signals was achieved using an automated odor emitter (OE) which is based on the controlled evaporation of a chemical analyte and its diffusion into a carrier gas stream. The chemical signals produced propagate within a confined channel to reach the demodulator-MS. Experiments were undertaken for a range of volatile organic compounds (VOCs) with different diffusion coefficient values in air at ambient conditions. Representative compounds investigated include acetone, cyclopentane, and n-hexane. For the first time, the binary code ASCII (American Standard Code for Information Interchange) is combined with chemical signaling to generate a molecular representation of the English alphabet. Transmission experiments of fixed-width molecular signals corresponding to letters of the alphabet over varying distances are shown. A binary message corresponding to the word "ion" was synthesized using chemical signals and transmitted within a physical channel over a distance of 2 m.
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Clique-Based Neural Associative Memories with Local Coding and Precoding.
Mofrad, Asieh Abolpour; Parker, Matthew G; Ferdosi, Zahra; Tadayon, Mohammad H
2016-08-01
Techniques from coding theory are able to improve the efficiency of neuroinspired and neural associative memories by forcing some construction and constraints on the network. In this letter, the approach is to embed coding techniques into neural associative memory in order to increase their performance in the presence of partial erasures. The motivation comes from recent work by Gripon, Berrou, and coauthors, which revisited Willshaw networks and presented a neural network with interacting neurons that partitioned into clusters. The model introduced stores patterns as small-size cliques that can be retrieved in spite of partial error. We focus on improving the success of retrieval by applying two techniques: doing a local coding in each cluster and then applying a precoding step. We use a slightly different decoding scheme, which is appropriate for partial erasures and converges faster. Although the ideas of local coding and precoding are not new, the way we apply them is different. Simulations show an increase in the pattern retrieval capacity for both techniques. Moreover, we use self-dual additive codes over field [Formula: see text], which have very interesting properties and a simple-graph representation.
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Impact of referral letters on scheduling of hospital appointments: a randomised control trial
Jiwa, Moyez; Meng, Xingqiong; O’Shea, Carolyn; Magin, Parker; Dadich, Ann; Pillai, Vinita
2014-01-01
Background Communication is essential for triage, but intervention trials to improve it are scarce. Referral Writer (RW), a referral letter software program, enables documentation of clinical data and extracts relevant patient details from clinical software. Aim To evaluate whether specialists are more confident about scheduling appointments when they receive more information in referral letters. Design and setting Single-blind, parallel-groups, controlled design with a 1:1 randomisation. Australian GPs watched video vignettes virtually. Method GPs wrote referral letters after watching vignettes of patients with cancer symptoms. Letter content was scored against a benchmark. The proportions of referral letters triagable by a specialist with confidence, and in which the specialist was confident the patient had potentially life-limiting pathology were determined. Categorical outcomes were tested with χ2 and continuous outcomes with t-tests. A random-effects logistic model assessed the influence of group randomisation (RW versus control), GP demographics, clinical specialty, and specialist referral assessor on specialist confidence in the information provided. Results The intervention (RW) group referred more patients and scored significantly higher on information relayed (mean difference 21.6 [95% confidence intervals {CI} = 20.1 to 23.2]). There was no difference in the proportion of letters for which specialists were confident they had sufficient information for appointment scheduling (RW 77.7% versus control 80.6%, P = 0.16). In the logistic model, limited agreement among specialists contributed substantially to the observed differences in appointment scheduling (P = 35% [95% CI 16% to 59%]). Conclusion In isolation, referral letter templates are unlikely to improve the scheduling of specialist appointments, even when more information is relayed. PMID:24982494
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Double Negative Materials (DNM), Phenomena and Applications
2009-07-01
Nanoparticles Formed by Pairs Of Concentric Double-Negative (DNG), Single-Negative ( SNG ) and/or Double-Positive (DPS) Metamaterial Layers.” J. Appl...material RRL Rapid Research Letters SHG second-harmonic generation SNG single-negative SSR split-ring resonator A-1 Appendix A. October 2008...Pairs of Concentric Double-Negative (DNG), Single-Negative ( SNG ), and/or Double-Positive (DPS) Metamaterial Layers.” J. Appl. Phys. 97, no. 9 (May
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BSPS Program (ESI-Mass Spectrometry) Biological Sample Data Analysis; Disruption of Bacteria Spores
2005-10-01
the original usage of the translational as a broad description of the entire process by which the polymer of the three-letter code in the mRNA is...translated. There is extensive review of post transnational modifications of proteins by Finn Wold(1981)24, given as in vivo chemical modifications... thiolation , biotin, bromination, carbamylation, deamidation, methylation, glu- cosylation, lipoyl, phosphorylation,, pyridoxal phosphate
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2009-02-19
Virginia 22203-1995 The Windy Island Soliton Experiment (WISE): Shallow Water and Basin Experiment Configuration and Preliminary Observations...case letters) The Windy Island Soliton Experiment (WISE): Shallow water and Basin Experiment Configuration and Preliminary Observations 5. FUNDING...release; distribution is unlimited 12b. DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) The Windy Islands Soliton Experiment (WISE) was
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Color-Coded Vowels and Spelling with Visual Cues in Beginning Reading.
ERIC Educational Resources Information Center
Turner, Ann Coffeen
Twenty-four beginning readers participated in a study of the effectiveness of cued learning. The study was carried out in two phases--a letter-learning phase and a word-learning phase. The children were taught one at a time by the same teacher over a four-year period. During the word-learning phase, one fourth of the children used a vowels-only…
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Mind wandering in text comprehension under dual-task conditions.
Dixon, Peter; Li, Henry
2013-01-01
In two experiments, subjects responded to on-task probes while reading under dual-task conditions. The secondary task was to monitor the text for occurrences of the letter e. In Experiment 1, reading comprehension was assessed with a multiple-choice recognition test; in Experiment 2, subjects recalled the text. In both experiments, the secondary task replicated the well-known "missing-letter effect" in which detection of e's was less effective for function words and the word "the." Letter detection was also more effective when subjects were on task, but this effect did not interact with the missing-letter effect. Comprehension was assessed in both the dual-task conditions and in control single-task conditions. In the single-task conditions, both recognition (Experiment 1) and recall (Experiment 2) was better when subjects were on task, replicating previous research on mind wandering. Surprisingly, though, comprehension under dual-task conditions only showed an effect of being on task when measured with recall; there was no effect on recognition performance. Our interpretation of this pattern of results is that subjects generate responses to on-task probes on the basis of a retrospective assessment of the contents of working memory. Further, we argue that under dual-task conditions, the contents of working memory is not closely related to the reading processes required for accurate recognition performance. These conclusions have implications for models of text comprehension and for the interpretation of on-task probe responses.
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Mind wandering in text comprehension under dual-task conditions
Dixon, Peter; Li, Henry
2013-01-01
In two experiments, subjects responded to on-task probes while reading under dual-task conditions. The secondary task was to monitor the text for occurrences of the letter e. In Experiment 1, reading comprehension was assessed with a multiple-choice recognition test; in Experiment 2, subjects recalled the text. In both experiments, the secondary task replicated the well-known “missing-letter effect” in which detection of e's was less effective for function words and the word “the.” Letter detection was also more effective when subjects were on task, but this effect did not interact with the missing-letter effect. Comprehension was assessed in both the dual-task conditions and in control single-task conditions. In the single-task conditions, both recognition (Experiment 1) and recall (Experiment 2) was better when subjects were on task, replicating previous research on mind wandering. Surprisingly, though, comprehension under dual-task conditions only showed an effect of being on task when measured with recall; there was no effect on recognition performance. Our interpretation of this pattern of results is that subjects generate responses to on-task probes on the basis of a retrospective assessment of the contents of working memory. Further, we argue that under dual-task conditions, the contents of working memory is not closely related to the reading processes required for accurate recognition performance. These conclusions have implications for models of text comprehension and for the interpretation of on-task probe responses. PMID:24101909
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An examination of iconic memory in children with autism spectrum disorders.
McMorris, Carly A; Brown, Stephanie M; Bebko, James M
2013-08-01
Iconic memory is the ability to accurately recall a number of items after a very brief visual exposure. Previous research has examined these capabilities in typically developing (TD) children and individuals with intellectual disabilities (ID); however, there is limited research on these abilities in children with Autism Spectrum Disorders (ASD). Twenty-one TD and eighteen ASD children were presented with circular visual arrays of letters for 100 ms and were asked to recall as many letters as possible or a single letter that was cued for recall. Groups did not differ in the number of items recalled, the rate of information decay, or speed of information processing. These findings suggest that iconic memory is an intact skill for children with ASD, a result that has implications for subsequent information processing.
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Lupker, Stephen J; Pexman, Penny M
2010-09-01
Performance in a lexical decision task is crucially dependent on the difficulty of the word-nonword discrimination. More wordlike nonwords cause not only a latency increase for words but also, as reported by Stone and Van Orden (1993), larger word frequency effects. Several current models of lexical decision making can explain these types of results in terms of a single mechanism, a mechanism driven by the nature of the interactions within the lexicon. In 2 experiments, we replicated Stone and Van Orden's increased frequency effect using both pseudohomophones (e.g., BEEST) and transposed-letter nonwords (e.g., JUGDE) as the more wordlike nonwords. In a 3rd experiment, we demonstrated that simply increasing word latencies without changing the difficulty of the word-nonword discrimination does not produce larger frequency effects. These results are reasonably consistent with many current models. In contrast, neither pseudohomophones nor transposed-letter nonwords altered the size of semantic priming effects across 4 additional experiments, posing a challenge to models that would attempt to explain both nonword difficulty effects and semantic priming effects in lexical decision tasks in terms of a single, lexically driven mechanism. (c) 2010 APA, all rights reserved).
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Nudging Guideline-Concordant Antibiotic Prescribing
Meeker, Daniella; Knight, Tara K.; Friedberg, Mark W.; Linder, Jeffrey A.; Goldstein, Noah J.; Fox, Craig R.; Rothfeld, Alan; Diaz, Guillermo; Doctor, Jason N.
2015-01-01
IMPORTANCE “Nudges” that influence decision making through subtle cognitive mechanisms have been shown to be highly effective in a wide range of applications, but there have been few experiments to improve clinical practice. OBJECTIVE To investigate the use of a behavioral “nudge” based on the principle of public commitment in encouraging the judicious use of antibiotics for acute respiratory infections (ARIs). DESIGN, SETTING, AND PARTICIPANTS Randomized clinical trial in 5 outpatient primary care clinics. A total of 954 adults had ARI visits during the study timeframe: 449 patients were treated by clinicians randomized to the posted commitment letter (335 in the baseline period, 114 in the intervention period); 505 patients were treated by clinicians randomized to standard practice control (384 baseline, 121 intervention). INTERVENTIONS The intervention consisted of displaying poster-sized commitment letters in examination rooms for 12 weeks. These letters, featuring clinician photographs and signatures, stated their commitment to avoid inappropriate antibiotic prescribing for ARIs. MAIN OUTCOMES AND MEASURES Antibiotic prescribing rates for antibiotic-inappropriate ARI diagnoses in baseline and intervention periods, adjusted for patient age, sex, and insurance status. RESULTS Baseline rates were 43.5% and 42.8% for control and poster, respectively. During the intervention period, inappropriate prescribing rates increased to 52.7% for controls but decreased to 33.7% in the posted commitment letter condition. Controlling for baseline prescribing rates, we found that the posted commitment letter resulted in a 19.7 absolute percentage reduction in inappropriate antibiotic prescribing rate relative to control (P = .02). There was no evidence of diagnostic coding shift, and rates of appropriate antibiotic prescriptions did not diminish over time. CONCLUSIONS AND RELEVANCE Displaying poster-sized commitment letters in examination rooms decreased inappropriate antibiotic prescribing for ARIs. The effect of this simple, low-cost intervention is comparable in magnitude to costlier, more intensive quality-improvement efforts. TRIAL REGISTRATION clinicaltrials.gov identifier: NCT01767064 PMID:24474434
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Code of Federal Regulations, 2011 CFR
2011-01-01
... Agency Under Public Law 103-354 Single Family Housing Loan Borrowers E Exhibit E to Subpart K of Part... Agency Under Public Law 103-354 Single Family Housing Loan Borrowers Dear (name of borrower): This is to.... Their counseling services include advice on debt levels and credit purchases, consumer and cost...
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Fin-line PIN-diode attenuators and switches for 94 GHz range
NASA Astrophysics Data System (ADS)
Meinel, H.; Callsen, H.
1982-06-01
The letter reports new results of fin-line PIN-diode attenuators and switches for the 94 GHz range. Design and performance of SPST and SPDT switches - single pole single throw and single pole double throw, respectively - will be presented. The attenuation of the SPST switch, for example, can be adjusted between 2 and 35 dB over the entire waveguide band from 75 to 110 GHz.
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Comparison of the optical parameters of a CaF{sub 2} single crystal and optical ceramics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Palashov, O V; Khazanov, E A; Mukhin, I B
Single crystal and optical ceramic CaF{sub 2} samples are studied by the method of thermally induced depolarisation of laser radiation at 1076 nm. The absorption coefficients of the single crystal and ceramics are estimated as {alpha} < 4.5x10{sup -4} cm{sup -1} and {alpha} < 1.33x10{sup -3} cm{sup -1}, respectively. (letters)
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Porto-Ferreira, Francisco Augusto; de Almeida-Neto, Cesar; Murphy, Edward L.; de Camargo Montebello, Sandra; Nogueira, Fátima Aparecida Hangai; Koga da Silva, Edina Mariko; MacFarland, William; Custer, Brian
2016-01-01
Introduction Low return rates for notification and counseling among donors with reactive serologic screening tests have been reported worldwide. A randomized trial to test the effectiveness of text message, letter or telephone call reminders to improve return among non-responding first-time blood donors with reactive serologic tests was conducted. Methods Donors with serologically reactive screening test results who had a cell phone and resided in the metropolitan telephone area code of São Paulo in the period from August 2013 through July 2014 were eligible. A consecutive sample of first-time donors with reactive screening tests who had not responded to a standard letter requesting the donor return to the blood center were randomly assigned to receive a text, a new letter or a telephone call requesting return for notification and counseling. Return rates were measured over the subsequent 30 days. Results Return following a phone call reminder was better than a text message (39.8% vs. 28.4%; OR=1.66; 95%CI 1.05–2.64) but not better than a letter (39.8% vs. 34.4%; OR=1.32; 95%CI 0.83–2.12). Older age was a predictor of higher rate of return with each year increase in age associated with a 2% increase in the odds of return (OR=1.02; 95%CI 1.01–1.04). Conclusion In non-responding serologic reactive donors, telephone call led to a higher return rate than text message. The results of this study suggest that use of text messages, while attractive for its simplicity, will not lead to increased donor notification success following serologically reactive marker results from blood donation in Brazil. PMID:27774609
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2014-01-01
Background Previously, we suggested prototypal models that describe some clinical states based on group postulates. Here, we demonstrate a group/category theory-like model for molecular/genetic biology as an alternative application of our previous model. Specifically, we focus on deoxyribonucleic acid (DNA) base sequences. Results We construct a wallpaper pattern based on a five-letter cruciform motif with letters C, A, T, G, and E. Whereas the first four letters represent the standard DNA bases, the fifth is introduced for ease in formulating group operations that reproduce insertions and deletions of DNA base sequences. A basic group Z5 = {r, u, d, l, n} of operations is defined for the wallpaper pattern, with which a sequence of points can be generated corresponding to changes of a base in a DNA sequence by following the orbit of a point of the pattern under operations in group Z5. Other manipulations of DNA sequence can be treated using a vector-like notation ‘Dj’ corresponding to a DNA sequence but based on the five-letter base set; also, ‘Dj’s are expressed graphically. Insertions and deletions of a series of letters ‘E’ are admitted to assist in describing DNA recombination. Likewise, a vector-like notation Rj can be constructed for sequences of ribonucleic acid (RNA). The wallpaper group B = {Z5×∞, ●} (an ∞-fold Cartesian product of Z5) acts on Dj (or Rj) yielding changes to Dj (or Rj) denoted by ‘Dj◦B(j→k) = Dk’ (or ‘Rj◦B(j→k) = Rk’). Based on the operations of this group, two types of groups—a modulo 5 linear group and a rotational group over the Gaussian plane, acting on the five bases—are linked as parts of the wallpaper group for broader applications. As a result, changes, insertions/deletions and DNA (RNA) recombination (partial/total conversion) are described. As an exploratory study, a notation for the canonical “central dogma” via a category theory-like way is presented for future developments. Conclusions Despite the large incompleteness of our methodology, there is fertile ground to consider a symmetry model for genetic coding based on our specific wallpaper group. A more integrated formulation containing “central dogma” for future molecular/genetic biology remains to be explored. PMID:24885369
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Changing the Engineering Student Culture with Respect to Academic Integrity and Ethics.
VanDeGrift, Tammy; Dillon, Heather; Camp, Loreal
2017-08-01
Engineers create airplanes, buildings, medical devices, and software, amongst many other things. Engineers abide by a professional code of ethics to uphold people's safety and the reputation of the profession. Likewise, students abide by a code of academic integrity while learning the knowledge and necessary skills to prepare them for the engineering and computing professions. This paper reports on studies designed to improve the engineering student culture with respect to academic integrity and ethics. To understand the existing culture at a university in the USA, a survey based on a national survey about cheating was administered to students. The incidences of self-reported cheating and incidences of not reporting others who cheat show the culture is similar to other institutions. Two interventions were designed and tested in an introduction to an engineering course: two case studies that students discussed in teams and the whole class, and a letter of recommendation assignment in which students wrote about themselves (character, strengths, examples of ethical decisions) three years into the future. Students were surveyed after the two interventions. Results show that first-year engineering students appreciate having a code of academic integrity and they want to earn their degree without cheating, yet less than half of the students would report on another cheating student. The letter of recommendation assignment had some impact on getting students to think about ethics, their character, and their actions. Future work in changing the student culture will continue in both a top-down (course interventions) and bottom-up (student-driven interventions) manner.
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Murphy, S F; Lenihan, L; Orefuwa, F; Colohan, G; Hynes, I; Collins, C G
2017-05-01
The discharge letter is a key component of the communication pathway between the hospital and primary care. Accuracy and timeliness of delivery are crucial to ensure continuity of patient care. Electronic discharge summaries (EDS) and prescriptions have been shown to improve quality of discharge information for general practitioners (GPs). The aim of this study was to evaluate the effect of a new EDS on GP satisfaction levels and accuracy of discharge diagnosis. A GP survey was carried out whereby semi-structured interviews were conducted with 13 GPs from three primary care centres who receive a high volume of discharge letters from the hospital. A chart review was carried out on 90 charts to compare accuracy of ICD-10 coding of Non-Consultant Hospital Doctors (NCHDs) with that of trained Hopital In-Patient Enquiry (HIPE) coders. GP satisfaction levels were over 90 % with most aspects of the EDS, including amount of information (97 %), accuracy (95 %), GP information and follow-up (97 %) and medications (91 %). 70 % of GPs received the EDS within 2 weeks. ICD-10 coding of discharge diagnosis by NCHDs had an accuracy of 33 %, compared with 95.6 % when done by trained coders (p < 0.00001). The introduction of the EDS and prescription has led to improved quality of timeliness of communication with primary care. It has led to a very high satisfaction rating with GPs. ICD-10 coding was found to be grossly inaccurate when carried out by NCHDs and it is more appropriate for this task to be carried out by trained coders.
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Construction of FuzzyFind Dictionary using Golay Coding Transformation for Searching Applications
NASA Astrophysics Data System (ADS)
Kowsari, Kamram
2015-03-01
searching through a large volume of data is very critical for companies, scientists, and searching engines applications due to time complexity and memory complexity. In this paper, a new technique of generating FuzzyFind Dictionary for text mining was introduced. We simply mapped the 23 bits of the English alphabet into a FuzzyFind Dictionary or more than 23 bits by using more FuzzyFind Dictionary, and reflecting the presence or absence of particular letters. This representation preserves closeness of word distortions in terms of closeness of the created binary vectors within Hamming distance of 2 deviations. This paper talks about the Golay Coding Transformation Hash Table and how it can be used on a FuzzyFind Dictionary as a new technology for using in searching through big data. This method is introduced by linear time complexity for generating the dictionary and constant time complexity to access the data and update by new data sets, also updating for new data sets is linear time depends on new data points. This technique is based on searching only for letters of English that each segment has 23 bits, and also we have more than 23-bit and also it could work with more segments as reference table.
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Hattenbach, Lars-Olof; Feltgen, Nicolas; Bertelmann, Thomas; Schmitz-Valckenberg, Steffen; Berk, Hüsnü; Eter, Nicole; Lang, Gabriele E; Rehak, Matus; Taylor, Simon R; Wolf, Armin; Weiss, Claudia; Paulus, Eva-Maria; Pielen, Amelie; Hoerauf, Hans
2018-02-01
To compare the efficacy and safety of ranibizumab 0.5 mg versus dexamethasone 0.7 mg according to their European labels in macular oedema secondary to branch retinal vein occlusion (BRVO) in a 6-month, phase IIIb, randomized trial. Patients received either monthly ranibizumab for 3 months followed by Pro re nata (PRN) treatment (n = 126) or a sustained-release dexamethasone implant followed by PRN sham injections (n = 118). Main outcomes were mean average change in best-corrected visual acuity (BCVA) from baseline to month 1 through month 6, mean changes in BCVA and foveal centre point thickness (FCPT), and adverse events (AEs). There was no difference in BCVA gains between the treatments prior to month 3. Best-corrected visual acuity (BCVA) gain with dexamethasone declined thereafter. From month 3 to month 6, mean BCVA change from baseline was significantly higher with ranibizumab than with dexamethasone [raw means (standard deviation):+16.2 (±11) letters versus +9.3 (±10.1) letters]. At month 6, the difference in BCVA gains from baseline was +17.3 letters in the ranibizumab versus +9.2 letters in the dexamethasone group. Patients in the ranibizumab group received a mean of 2.94 loading injections and 1.74 PRN retreatment injections, while those in the dexamethasone group received a single loading injection. Elevated intraocular pressure (IOP) and AEs were more frequent with dexamethasone than ranibizumab treatment. Ranibizumab PRN resulted in greater visual acuity (VA) gains in macular oedema following BRVO compared with single-dose dexamethasone over a 6-month study period, observed from month 3, when administered according to their European label. In clinical practice, retreatment with dexamethasone may be required prior to this point. © 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
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Lobier, Muriel; Peyrin, Carole; Le Bas, Jean-François; Valdois, Sylviane
2012-07-01
The visual front-end of reading is most often associated with orthographic processing. The left ventral occipito-temporal cortex seems to be preferentially tuned for letter string and word processing. In contrast, little is known of the mechanisms responsible for pre-orthographic processing: the processing of character strings regardless of character type. While the superior parietal lobule has been shown to be involved in multiple letter processing, further data is necessary to extend these results to non-letter characters. The purpose of this study is to identify the neural correlates of pre-orthographic character string processing independently of character type. Fourteen skilled adult readers carried out multiple and single element visual categorization tasks with alphanumeric (AN) and non-alphanumeric (nAN) characters under fMRI. The role of parietal cortex in multiple element processing was further probed with a priori defined anatomical regions of interest (ROIs). Participants activated posterior parietal cortex more strongly for multiple than single element processing. ROI analyses showed that bilateral SPL/BA7 was more strongly activated for multiple than single element processing, regardless of character type. In contrast, no multiple element specific activity was found in inferior parietal lobules. These results suggests that parietal mechanisms are involved in pre-orthographic character string processing. We argue that in general, attentional mechanisms are involved in visual word recognition, as an early step of word visual analysis. Copyright © 2012 Elsevier Ltd. All rights reserved.
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Starrfelt, Randi; Klargaard, Solja K; Petersen, Anders; Gerlach, Christian
2018-02-01
Recent models suggest that face and word recognition may rely on overlapping cognitive processes and neural regions. In support of this notion, face recognition deficits have been demonstrated in developmental dyslexia. Here we test whether the opposite association can also be found, that is, impaired reading in developmental prosopagnosia. We tested 10 adults with developmental prosopagnosia and 20 matched controls. All participants completed the Cambridge Face Memory Test, the Cambridge Face Perception test and a Face recognition questionnaire used to quantify everyday face recognition experience. Reading was measured in four experimental tasks, testing different levels of letter, word, and text reading: (a) single word reading with words of varying length,(b) vocal response times in single letter and short word naming, (c) recognition of single letters and short words at brief exposure durations (targeting the word superiority effect), and d) text reading. Participants with developmental prosopagnosia performed strikingly similar to controls across the four reading tasks. Formal analysis revealed a significant dissociation between word and face recognition, as the difference in performance with faces and words was significantly greater for participants with developmental prosopagnosia than for controls. Adult developmental prosopagnosics read as quickly and fluently as controls, while they are seemingly unable to learn efficient strategies for recognizing faces. We suggest that this is due to the differing demands that face and word recognition put on the perceptual system. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
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Kahn-Horwitz, Janina; Shimron, Joseph; Sparks, Richard L
2006-06-01
This study examined individual differences among beginning readers of English as a foreign language (EFL). The study concentrated on the effects of underlying first language (L1) knowledge as well as EFL letter and vocabulary knowledge. Phonological and morphological awareness, spelling, vocabulary knowledge, and word reading in Hebrew L1, in addition to knowledge of EFL letters and EFL vocabulary, were measured. The study also investigated the effect of socioeconomic background (SES) on beginning EFL readers. Participants included 145 fourth graders from three schools representing two socioeconomic backgrounds in the north of Israel. The results indicate that knowledge of English letters played a more prominent role than knowledge of Hebrew L1 components in differentiating between strong and weak EFL readers. The Linguistic Coding Differences Hypothesis was supported by L1 phonological awareness, word reading, and vocabulary knowledge appearing as part of discriminating functions. The presence of English vocabulary knowledge as part of the discriminant functions provides support for English word reading being more than just a decoding task for EFL beginner readers. Socioeconomic status differentiated the groups for EFL word recognition but not for EFL reading comprehension.
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A working memory account of the interaction between numbers and spatial attention.
van Dijck, Jean-Philippe; Abrahamse, Elger L; Acar, Freya; Ketels, Boris; Fias, Wim
2014-01-01
Rather than reflecting the long-term memory construct of a mental number line, it has been proposed that the relation between numbers and space is of a more temporary nature and constructed in working memory during task execution. In three experiments we further explored the viability of this working memory account. Participants performed a speeded dot detection task with dots appearing left or right, while maintaining digits or letters in working memory. Just before presentation of the dot, these digits or letters were used as central cues. These experiments show that the "attentional SNARC-effect" (where SNARC is the spatial-numerical association of response codes) is not observed when only the lastly perceived number cue--and no serially ordered sequence of cues--is maintained in working memory (Experiment 1). It is only when multiple items (numbers in Experiment 2; letters in Experiment 3) are stored in working memory in a serially organized way that the attentional cueing effect is observed as a function of serial working memory position. These observations suggest that the "attentional SNARC-effect" is strongly working memory based. Implications for theories on the mental representation of numbers are discussed.
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Khelifi, Rachid; Sparrow, Laurent; Casalis, Séverine
2015-11-01
We assessed third and fifth graders' processing of parafoveal word information using a lexical decision task. On each trial, a preview word was first briefly presented parafoveally in the left or right visual field before a target word was displayed. Preview and target words could be identical, share the first three letters, or have no letters in common. Experiment 1 showed that developing readers receive the same word recognition benefit from parafoveal previews as expert readers. The impact of a change of case between preview and target in Experiment 2 showed that in all groups of readers, the preview benefit resulted from the identification of letters at an abstract level rather than from facilitation at a purely visual level. Fifth graders identified more letters from the preview than third graders. The results are interpreted within the framework of the interactive activation model. In particular, we suggest that although the processing of parafoveal information led to letter identification in developing readers, the processes involved may differ from those in expert readers. Although expert readers' processing of parafoveal information led to activation at the level of lexical representations, no such activation was observed in developing readers. Copyright © 2015 Elsevier Inc. All rights reserved.
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1988-09-01
CIT C 15 Name of local city. InCSrATE C 2 Name of local state as tw letter abbreviatiom. SIC ZIP C 10 Loa ZIP code. Five or nine digits . InC_ PHKtE C 15...record: 10 Database Dictimary for C: \\ BASE\\PAS1E.MF Field Nane Type Width Decimal Coments PMSCODE C 2 Third and fourth digits of PAS code. ON C 3...Version: 3.01 Date: 09/01/88 Time: 21:34 Report Libary : C: ASE\\GPO.RP1 Date: 08/28/88 Time: 11:32 PRMNT OFTICNS CflRL-PRINrM Nmber of copies: 1 Starting
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Approximated transport-of-intensity equation for coded-aperture x-ray phase-contrast imaging.
Das, Mini; Liang, Zhihua
2014-09-15
Transport-of-intensity equations (TIEs) allow better understanding of image formation and assist in simplifying the "phase problem" associated with phase-sensitive x-ray measurements. In this Letter, we present for the first time to our knowledge a simplified form of TIE that models x-ray differential phase-contrast (DPC) imaging with coded-aperture (CA) geometry. The validity of our approximation is demonstrated through comparison with an exact TIE in numerical simulations. The relative contributions of absorption, phase, and differential phase to the acquired phase-sensitive intensity images are made readily apparent with the approximate TIE, which may prove useful for solving the inverse phase-retrieval problem associated with these CA geometry based DPC.
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Word and pseudoword superiority effects reflected in the ERP waveform
Coch, Donna; Mitra, Priya
2010-01-01
A variant of the Reicher-Wheeler task was used to determine when in the event-related potential (ERP) waveform indices of word and pseudoword superiority effects might be present, and whether ERP measures of superiority effects correlated with standardized behavioral measures of orthographic fluency and single word reading. ERPs were recorded to briefly presented, masked letter strings that included real words (DARK/PARK), pseudowords (DARL/PARL), nonwords (RDKA/RPKA), and letter-in-xs (DXXX, PXXX) stimuli. Participants decided which of two letters occurred at a given position in the string (here, forced-choice alternatives D and P). Behaviorally, both word (more accurate choices for letters in words than in baseline nonwords or letter-in-xs) and pseudoword (more accurate choices for letters in pseudowords than in baseline conditions) superiority effects were observed. Electrophysiologically, effects of orthographic regularity and familiarity were apparent as early as the P150 time window (100–160 ms), an effect of lexicality was observed as early as the N200 time window (160–200 ms), and peak amplitude of the N300 and N400 also differentiated word and pseudoword as compared to baseline stimuli. Further, the size of the P150 and N400 ERP word superiority effects was related to standardized behavioral measures of fluency and reading. Results suggest that orthographic fluency is reflected in both lower-level, sublexical, perceptual processing and higher-level, lexical processing in fluently reading adults. PMID:20211607
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Montgomery, Catharine; Fisk, John E; Newcombe, Russell; Murphy, Phillip N
2005-10-01
Recent theoretical models suggest that the central executive may not be a unified structure. The present study explored the nature of central executive deficits in ecstasy users. In study 1, 27 ecstasy users and 34 non-users were assessed using tasks to tap memory updating (computation span; letter updating) and access to long-term memory (a semantic fluency test and the Chicago Word Fluency Test). In study 2, 51 ecstasy users and 42 non-users completed tasks that assess mental set switching (number/letter and plus/minus) and inhibition (random letter generation). MANOVA revealed that ecstasy users performed worse on both tasks used to assess memory updating and on tasks to assess access to long-term memory (C- and S-letter fluency). However, notwithstanding the significant ecstasy group-related effects, indices of cocaine and cannabis use were also significantly correlated with most of the executive measures. Unexpectedly, in study 2, ecstasy users performed significantly better on the inhibition task, producing more letters than non-users. No group differences were observed on the switching tasks. Correlations between indices of ecstasy use and number of letters produced were significant. The present study provides further support for ecstasy/polydrug-related deficits in memory updating and in access to long-term memory. The surplus evident on the inhibition task should be treated with some caution, as this was limited to a single measure and has not been supported by our previous work.
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Interpreting instructional cues in task switching procedures: the role of mediator retrieval.
Logan, Gordon D; Schneider, Darryl W
2006-03-01
In 3 experiments the role of mediators in task switching with transparent and nontransparent cues was examined. Subjects switched between magnitude (greater or less than 5) and parity (odd or even) judgments of single digits. A cue-target congruency effect indicated mediator use: subjects responded faster to congruent cue-target combinations (e.g., ODD-3) than to incongruent cue-target combinations (e.g., ODD-4). Experiment 1 revealed significant congruency effects with transparent word cues (ODD, EVEN, HIGH, and LOW) and with relatively transparent letter cues (O, E, H, and L) but not with nontransparent letter cues (D, V, G, and W). Experiment 2 revealed significant congruency effects after subjects who were trained with nontransparent letter cues were informed of the relations between cues and word mediators halfway through the experiment. Experiment 3 showed that congruency effects with relatively transparent letter cues diminished over 10 sessions of practice, suggesting that subjects used mediators less as practice progressed. The results are discussed in terms of the role of mediators in interpreting instructional cues.
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Optical levitation of a microdroplet containing a single quantum dot.
Minowa, Yosuke; Kawai, Ryoichi; Ashida, Masaaki
2015-03-15
We demonstrate the optical levitation or trapping in helium gas of a single quantum dot (QD) within a liquid droplet. Bright single photon emission from the levitated QD in the droplet was observed for more than 200 s. The observed photon count rates are consistent with the value theoretically estimated from the two-photon-action cross section. This Letter presents the realization of an optically levitated solid-state quantum emitter.
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Bock, Otmar L; Dalecki, Marc
2015-04-01
It is known that in mental-rotation tasks, subjects mentally transform the displayed material until it appears "upright" and then make a judgment. Here we evaluate, by using three typical mental rotation tasks with different degrees of embodiment, whether "upright" is coded to a gravitational or egocentric reference frame, or a combination of both. Observers stood erect or were whole-body tilted by 60°, with their left ear down. In either posture, they saw stimuli presented at different orientation angles in their frontal plane: in condition LETTER, they judged whether the stimuli were normal or mirror-reversed letters, in condition HAND whether they represented a left or a right hand, and in condition SCENE whether a weapon laid left or right in front of a displayed person. Data confirm that reaction times are modulated by stimulus orientation angle, and the modulation curve in LETTER and HAND differs from that in SCENE. More importantly, during 60° body tilt, the modulation curve shifted 12° away from the gravitational towards the egocentric vertical reference; this shift was comparable in all three conditions and independent of the degree of embodiment. We conclude that mental rotation in all conditions relied on a similar spatial reference, which seems to be a weighted average of the gravitational and the egocentric vertical, with a higher weight given to the former. Copyright © 2015 Elsevier B.V. All rights reserved.
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Brain mechanisms of recovery from pure alexia: A single case study with multiple longitudinal scans.
Cohen, Laurent; Dehaene, Stanislas; McCormick, Samantha; Durant, Szonya; Zanker, Johannes M
2016-10-01
Pure alexia is an acquired reading disorder, typically due to a left occipito-temporal lesion affecting the Visual Word Form Area (VWFA). It is unclear whether the VWFA acts as a unique bottleneck for reading, or whether alternative routes are available for recovery. Here, we address this issue through the single-case longitudinal study of a neuroscientist who experienced pure alexia and participated in 17 behavioral, 9 anatomical, and 9 fMRI assessment sessions over a period of two years. The origin of the impairment was assigned to a small left fusiform lesion, accompanied by a loss of VWFA responsivity and by the degeneracy of the associated white matter pathways. fMRI experiments allowed us to image longitudinally the visual perception of words, as compared to other classes of stimuli, as well as the mechanisms of letter-by-letter reading. The progressive improvement of reading was not associated with the re-emergence of a new area selective to words, but with increasing responses in spared occipital cortex posterior to the lesion and in contralateral right occipital cortex. Those regions showed a non-specific increase of activations over time and an increase in functional correlation with distant language areas. Those results confirm the existence of an alternative occipital route for reading, bypassing the VWFA, but they also point to its key limitation: the patient remained a slow letter-by-letter reader, thus supporting the critical importance of the VWFA for the efficient parallel recognition of written words. Copyright © 2016 Elsevier Ltd. All rights reserved.
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Metzker, Manja; Dreisbach, Gesine
2011-06-01
Recently, it was proposed that the Simon effect would result not only from two interfering processes, as classical dual-route models assume, but from three processes. It was argued that priming from the spatial code to the nonspatial code might facilitate the identification of the nonspatial stimulus feature in congruent Simon trials. In the present study, the authors provide evidence that the identification of the nonspatial information can be facilitated by the activation of an associated spatial code. In three experiments, participants first associated centrally presented animal and fruit pictures with spatial responses. Subsequently, participants decided whether laterally presented letter strings were words (animal, fruit, or other words) or nonwords; stimulus position could be congruent or incongruent to the associated spatial code. As hypothesized, animal and fruit words were identified faster at congruent than at incongruent stimulus positions from the association phase. The authors conclude that the activation of the spatial code spreads to the nonspatial code, resulting in facilitated stimulus identification in congruent trials. These results speak to the assumption of a third process involved in the Simon task.
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Zhang, Chenchu; Hu, Yanlei; Du, Wenqiang; Wu, Peichao; Rao, Shenglong; Cai, Ze; Lao, Zhaoxin; Xu, Bing; Ni, Jincheng; Li, Jiawen; Zhao, Gang; Wu, Dong; Chu, Jiaru; Sugioka, Koji
2016-01-01
Rapid integration of high-quality functional devices in microchannels is in highly demand for miniature lab-on-a-chip applications. This paper demonstrates the embellishment of existing microfluidic devices with integrated micropatterns via femtosecond laser MRAF-based holographic patterning (MHP) microfabrication, which proves two-photon polymerization (TPP) based on spatial light modulator (SLM) to be a rapid and powerful technology for chip functionalization. Optimized mixed region amplitude freedom (MRAF) algorithm has been used to generate high-quality shaped focus field. Base on the optimized parameters, a single-exposure approach is developed to fabricate 200 × 200 μm microstructure arrays in less than 240 ms. Moreover, microtraps, QR code and letters are integrated into a microdevice by the advanced method for particles capture and device identification. These results indicate that such a holographic laser embellishment of microfluidic devices is simple, flexible and easy to access, which has great potential in lab-on-a-chip applications of biological culture, chemical analyses and optofluidic devices. PMID:27619690
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Coding for Single-Line Transmission
NASA Technical Reports Server (NTRS)
Madison, L. G.
1983-01-01
Digital transmission code combines data and clock signals into single waveform. MADCODE needs four standard integrated circuits in generator and converter plus five small discrete components. MADCODE allows simple coding and decoding for transmission of digital signals over single line.
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McClure, Jennifer B; Anderson, Melissa L
2018-02-08
Most smokers do not use evidence-based smoking cessation treatment. Increasing utilization of these services is an important public health goal. Health care systems and insurers are well positioned to support this goal within their patient populations. We tested whether a brief, mail-based intervention increased utilization of tobacco cessation services among insured smokers. Adult smokers were identified via automated health plan data and randomized to one of five treatment arms (n = 4767). Randomization was stratified by gender, age, and type of health plan coverage. Three arms received a letter containing motivational content and treatment referral information. Motivational content emphasized either the financial, health, or values-based benefits of quitting. One arm received a referral letter with no motivational content, and one arm received no letter. Enrollment in the referred tobacco cessation program was monitored for 5 months. Treatment was available to all participants through their insurance. Across all four letter conditions, 0.8% of participants enrolled in tobacco treatment compared to 0.9% in the no letter reference group (p = .69). No single letter condition was superior to the others (p = .71), but treatment uptake was greater among participants who received their care and coverage from the health plan versus those with insurance coverage only (1.2% vs. 0.3%, p < .01). A one-time, mailed letter is not a cost-effective strategy for promoting use of covered smoking cessation treatment within large health plan populations, particularly when the message source is an insurance provider only and does not also provide clinical care. Health plans and insurers should consider alternative outreach efforts to promote treatment uptake among smokers. TRN registered retrospectively with ISRCTN registry ( www.isrctn.com ). Registered on 11/01/2018. Registration number: ISRCTN32311137 .
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Wernick, M; Hale, P; Anticich, N; Busch, S; Merriman, L; King, B; Pegg, T
2016-05-01
There is little existing research on the role that secondary care letters have in ensuring patient understanding of chronic health conditions. To determine whether minimising the use of medical terminology in medical correspondence improved patient understanding and anxiety/depression scores. A single-centre, non-blinded, randomised crossover design assessed health literacy, EQ-5D scores and the impact of the 'translated' letter on the doctor's professionalism, the patient's relationship with their general practitioner (GP) and their perceived impact on chronic disease management. Patients were crossed over between their 'translated' and original letter. Sixty patients were recruited. Use of a 'translated' letter reduced mean terms not understood from 7.78 to 1.76 (t(58) = 4.706, P < 0.001). Most patients (78.0%) preferred the 'translated' letter, with 69.5% patients perceiving an enhancement in their doctor's professionalism (z = 2.864, P = 0.004), 69.0% reporting a positive influence on relationship with their GP (z = 2.943, P = 0.003) and 79.7% reporting an increase in perceived ability to manage their chronic health condition with the 'translated' letter (z = 4.601, P < 0.001). There was no effect on EQ-5D depression/anxiety scores. Minimising the use of medical terminology in medical correspondence significantly improved patient understanding and perception of their ability to manage their chronic health condition. Although there was no impact on EQ-5D depression/anxiety scores, overwhelming patient preference for the 'translated' letter indicates a need for minimisation of medical terminology in medical correspondence for patients with chronic health conditions. © 2016 Royal Australasian College of Physicians.
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Spatial-frequency requirements for reading revisited
Kwon, MiYoung; Legge, Gordon E.
2012-01-01
Blur is one of many visual factors that can limit reading in both normal and low vision. Legge et al. [Legge, G. E., Pelli, D. G., Rubin, G. S., & Schleske, M. M. (1985). Psychophysics of reading. I. Normal vision. Vision Research, 25, 239–252.] measured reading speed for text that was low-pass filtered with a range of cutoff spatial frequencies. Above 2 cycles per letter (CPL) reading speed was constant at its maximum level, but decreased rapidly for lower cutoff frequencies. It remains unknown why the critical cutoff for reading speed is near 2 CPL. The goal of the current study was to ask whether the spatial-frequency requirement for rapid reading is related to the effects of cutoff frequency on letter recognition and the size of the visual span. Visual span profiles were measured by asking subjects to recognize letters in trigrams (random strings of three letters) flashed for 150 ms at varying letter positions left and right of the fixation point. Reading speed was measured with Rapid Serial Visual Presentation (RSVP). The size of the visual span and reading speed were measured for low-pass filtered stimuli with cutoff frequencies from 0.8 to 8 CPL. Low-pass letter recognition data, obtained under similar testing conditions, were available from our previous study (Kwon & Legge, 2011). We found that the spatial-frequency requirement for reading is very similar to the spatial-frequency requirements for the size of the visual span and single letter recognition. The critical cutoff frequencies for reading speed, the size of the visual span and a contrast-invariant measure of letter recognition were all near 1.4 CPL, which is lower than the previous estimate of 2 CPL for reading speed. Although correlational in nature, these results are consistent with the hypothesis that the size of the visual span is closely linked to reading speed. PMID:22521659
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Unconditional security of a three state quantum key distribution protocol.
Boileau, J-C; Tamaki, K; Batuwantudawe, J; Laflamme, R; Renes, J M
2005-02-04
Quantum key distribution (QKD) protocols are cryptographic techniques with security based only on the laws of quantum mechanics. Two prominent QKD schemes are the Bennett-Brassard 1984 and Bennett 1992 protocols that use four and two quantum states, respectively. In 2000, Phoenix et al. proposed a new family of three-state protocols that offers advantages over the previous schemes. Until now, an error rate threshold for security of the symmetric trine spherical code QKD protocol has been shown only for the trivial intercept-resend eavesdropping strategy. In this Letter, we prove the unconditional security of the trine spherical code QKD protocol, demonstrating its security up to a bit error rate of 9.81%. We also discuss how this proof applies to a version of the trine spherical code QKD protocol where the error rate is evaluated from the number of inconclusive events.
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Engineering and Design: Indoor Radon Prevention and Mitigation
1993-09-15
slabs on grade, capillary water barrier below floor slabs on grade, dampproofing or waterproofing and protection board on below grade walls, sealants in...will be lapped 12 inches and sealed with adhesives or pressure sensitive tape and sealed at foundation walls with mastic. Capillary water barrier will...Systems, Letter Codes B, C, and D. Sub- slab suction systems consist of 4 inch diameter perforated PVC pipe laid in the capillary water barrier below floor
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Crude oil produced by church not exempt from windfall profit tax
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1985-09-01
Private Letter Ruling 8515003 does not exempt crude oil produced by an agency of a convention of churches from the windfall profits tax. The Internal Revenue Service concluded that not all of the proceeds were dedicated for the benefit of a qualifying charitable organization since some went to build a home for the elderly, although some went to fund educational scholarships. The Code does not allow partial tax exemptions.
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2016-05-03
using additional English resources. 2. Background The Babel program1 is an international collaborative effort sponsored by the US Intelligence Advanced...phenomenon is not as well studied for English / African language pairs, but some results are available8,9. 3. Experimental Setup The Swahili analysis...word pronunciations. From the analysis it was concluded that in most cases English words were pronounced using standard English letter-to-sound rules
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2011-10-01
working memory),(Vanderploeg et al., 2005) Wechsler Adult Intelligence Scale III (WAIS-III) items: Digit Symbol Coding, Digit Span, Letter-Number...EFFORT William C. Walker, MD, Principal Investigator September, 2008 20 (see: VCU sub-award) David X. Cifu, MD Co-Investigator September, 2008...group for our purposes. The neuropsychological battery will consist of the following standardized, validated, tests of proven reliability: Wechsler Test
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1985-12-31
34 Optics Letters, 2 (1), 1-3 (1978). 7. Grossberg, S., "Adaptive Resonance in Development, Perception and Cognition ," SIAM-AMS Proc., 13, 107-156...Illusions," Biol. Cybernetics, 23, 187-202, (1976b). 11. Grossberg, S., "How Does A Brain Build a Cognitive Code?", Psychol. Review, 87 (1), 1-51 (1980...34perceptron" (F. Rosenblatt, Principles of Neurodynamics ), workers in the neural network field have been seeking to understand how neural networks can perform
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Thomassen, K I
The SSPX Thermistor is a glass encapsulated bead thermistor made by Thermometrics, a BR 14 P A 103 J. The BR means ruggedized bead structure, 14 is the nominal bead diameter in mils, P refers to opposite end leads, A is the material system code letter, 103 refers to its 10 k{Omega} zero-power resistance at 25 C, and the tolerance letter J indicates {+-} 5% at 25 C. It is football shaped, with height ->, and is viewed through a slot of height h = 0.01 inches. The slot is perpendicular to the long axis of the bead, and ismore » a distance s {approx} 0.775 cm in front of the thermistor. So plasma is viewed over a large angle along the slot, but over a small angle {alpha} perpendicular to the slot. The angle {alpha} is given by 2s tan{alpha} = -> + h.« less
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Beaton, Derek; Dunlop, Joseph; Abdi, Hervé
2016-12-01
For nearly a century, detecting the genetic contributions to cognitive and behavioral phenomena has been a core interest for psychological research. Recently, this interest has been reinvigorated by the availability of genotyping technologies (e.g., microarrays) that provide new genetic data, such as single nucleotide polymorphisms (SNPs). These SNPs-which represent pairs of nucleotide letters (e.g., AA, AG, or GG) found at specific positions on human chromosomes-are best considered as categorical variables, but this coding scheme can make difficult the multivariate analysis of their relationships with behavioral measurements, because most multivariate techniques developed for the analysis between sets of variables are designed for quantitative variables. To palliate this problem, we present a generalization of partial least squares-a technique used to extract the information common to 2 different data tables measured on the same observations-called partial least squares correspondence analysis-that is specifically tailored for the analysis of categorical and mixed ("heterogeneous") data types. Here, we formally define and illustrate-in a tutorial format-how partial least squares correspondence analysis extends to various types of data and design problems that are particularly relevant for psychological research that include genetic data. We illustrate partial least squares correspondence analysis with genetic, behavioral, and neuroimaging data from the Alzheimer's Disease Neuroimaging Initiative. R code is available on the Comprehensive R Archive Network and via the authors' websites. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
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Common constraints limit Korean and English character recognition in peripheral vision.
He, Yingchen; Kwon, MiYoung; Legge, Gordon E
2018-01-01
The visual span refers to the number of adjacent characters that can be recognized in a single glance. It is viewed as a sensory bottleneck in reading for both normal and clinical populations. In peripheral vision, the visual span for English characters can be enlarged after training with a letter-recognition task. Here, we examined the transfer of training from Korean to English characters for a group of bilingual Korean native speakers. In the pre- and posttests, we measured visual spans for Korean characters and English letters. Training (1.5 hours × 4 days) consisted of repetitive visual-span measurements for Korean trigrams (strings of three characters). Our training enlarged the visual spans for Korean single characters and trigrams, and the benefit transferred to untrained English symbols. The improvement was largely due to a reduction of within-character and between-character crowding in Korean recognition, as well as between-letter crowding in English recognition. We also found a negative correlation between the size of the visual span and the average pattern complexity of the symbol set. Together, our results showed that the visual span is limited by common sensory (crowding) and physical (pattern complexity) factors regardless of the language script, providing evidence that the visual span reflects a universal bottleneck for text recognition.
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Common constraints limit Korean and English character recognition in peripheral vision
He, Yingchen; Kwon, MiYoung; Legge, Gordon E.
2018-01-01
The visual span refers to the number of adjacent characters that can be recognized in a single glance. It is viewed as a sensory bottleneck in reading for both normal and clinical populations. In peripheral vision, the visual span for English characters can be enlarged after training with a letter-recognition task. Here, we examined the transfer of training from Korean to English characters for a group of bilingual Korean native speakers. In the pre- and posttests, we measured visual spans for Korean characters and English letters. Training (1.5 hours × 4 days) consisted of repetitive visual-span measurements for Korean trigrams (strings of three characters). Our training enlarged the visual spans for Korean single characters and trigrams, and the benefit transferred to untrained English symbols. The improvement was largely due to a reduction of within-character and between-character crowding in Korean recognition, as well as between-letter crowding in English recognition. We also found a negative correlation between the size of the visual span and the average pattern complexity of the symbol set. Together, our results showed that the visual span is limited by common sensory (crowding) and physical (pattern complexity) factors regardless of the language script, providing evidence that the visual span reflects a universal bottleneck for text recognition. PMID:29327041
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Tracing information flow on a global scale using Internet chain-letter data
Liben-Nowell, David; Kleinberg, Jon
2008-01-01
Although information, news, and opinions continuously circulate in the worldwide social network, the actual mechanics of how any single piece of information spreads on a global scale have been a mystery. Here, we trace such information-spreading processes at a person-by-person level using methods to reconstruct the propagation of massively circulated Internet chain letters. We find that rather than fanning out widely, reaching many people in very few steps according to “small-world” principles, the progress of these chain letters proceeds in a narrow but very deep tree-like pattern, continuing for several hundred steps. This suggests a new and more complex picture for the spread of information through a social network. We describe a probabilistic model based on network clustering and asynchronous response times that produces trees with this characteristic structure on social-network data. PMID:18353985
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Vařeková, Radka Svobodová; Jaiswal, Deepti; Sehnal, David; Ionescu, Crina-Maria; Geidl, Stanislav; Pravda, Lukáš; Horský, Vladimír; Wimmerová, Michaela; Koča, Jaroslav
2014-07-01
Structure validation has become a major issue in the structural biology community, and an essential step is checking the ligand structure. This paper introduces MotiveValidator, a web-based application for the validation of ligands and residues in PDB or PDBx/mmCIF format files provided by the user. Specifically, MotiveValidator is able to evaluate in a straightforward manner whether the ligand or residue being studied has a correct annotation (3-letter code), i.e. if it has the same topology and stereochemistry as the model ligand or residue with this annotation. If not, MotiveValidator explicitly describes the differences. MotiveValidator offers a user-friendly, interactive and platform-independent environment for validating structures obtained by any type of experiment. The results of the validation are presented in both tabular and graphical form, facilitating their interpretation. MotiveValidator can process thousands of ligands or residues in a single validation run that takes no more than a few minutes. MotiveValidator can be used for testing single structures, or the analysis of large sets of ligands or fragments prepared for binding site analysis, docking or virtual screening. MotiveValidator is freely available via the Internet at http://ncbr.muni.cz/MotiveValidator. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.
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Poletti, Michele
2016-01-01
The fifth edition of theDiagnostic and Statistical Manual of Mental Disordersgrouped specific learning disabilities in the single diagnostic category of specific learning disorder (SLD), with specifiers for impairments in reading, written expression, and mathematics. This study aimed at investigating the intellectual profile, assessed with the fourth edition of theWechsler Intelligence Scale for Children(WISC-IV), of 172 children with a diagnosis of SLD, compared to 74 clinical referral controls. WISC-IV intellectual functioning in children with SLD was characterized by a significant discrepancy between general ability and cognitive proficiency (General Ability Index [GAI] > Cognitive Proficiency Index [CPI]), and worse performances on the Similarities, Digit Span, Letter-Number Sequencing, and Coding subtests, supporting models of multiple cognitive deficits at the basis of neurodevelopmental disorders as SLD. GAI was the best and more conservative measure provided by the WISC-IV to identify intellectual functioning in children with SLD, and the intellectual discrepancy between GAI and CPI could be considered a "cognitive sign" for the presence of SLD in a single diagnostic category. Cognitive deficits differed in subtypes of impairment (reading, written expression, and mathematics), supporting their distinction for empirical, educational, and rehabilitative purposes. These findings need further replication in larger samples and in comparison to typically developing children. © Hammill Institute on Disabilities 2014.
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Seeing red: Relearning to read in a case of Balint's Syndrome.
Rose, Anita; Wilson, Barbara A; Manolov, Rumen; Florschutz, Gerhard
2016-06-18
Balint's Syndrome is a rare condition, often associated with hypoxic brain damage. The major characteristic is an inability to localise objects in space, another is simultanagnosia frequently resulting in reading difficulties. We present RN, a 37 year old woman whose major problem with reading was her inability to recognise individual letters correctly in either lower or upper case. We noted, however, that she was better if the letters were shown in red type. The aims were to determine if RN could relearn letters of the alphabet, investigate whether colour affected her ability to learn, and to explore more specifically whether the red type also helped her to read words. Using a single case experimental ABA design, we first determined that the optimal font for RN was size 16. In the baseline (A) phase, we assessed her ability to read all lower and upper case letters of the alphabet in black ink. In the intervention (B) phase we used font size 16 in red ink and an errorless learning approach to teaching the letters. Sessions ran 5 times per week (20 minutes per session). The intervention was then applied to picture recognition and word reading with four sets of 10 words and corresponding pictures. A consistent difference was noted between initial baseline and intervention. Improvement carried over when we returned to baseline. Using red type and an errorless learning approach enabled RN to re-learn letters of the alphabet and read words she was previously unable to read. This did not however generalise to her everyday life.
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Grouping in object recognition: the role of a Gestalt law in letter identification.
Pelli, Denis G; Majaj, Najib J; Raizman, Noah; Christian, Christopher J; Kim, Edward; Palomares, Melanie C
2009-02-01
The Gestalt psychologists reported a set of laws describing how vision groups elements to recognize objects. The Gestalt laws "prescribe for us what we are to recognize 'as one thing'" (Kohler, 1920). Were they right? Does object recognition involve grouping? Tests of the laws of grouping have been favourable, but mostly assessed only detection, not identification, of the compound object. The grouping of elements seen in the detection experiments with lattices and "snakes in the grass" is compelling, but falls far short of the vivid everyday experience of recognizing a familiar, meaningful, named thing, which mediates the ordinary identification of an object. Thus, after nearly a century, there is hardly any evidence that grouping plays a role in ordinary object recognition. To assess grouping in object recognition, we made letters out of grating patches and measured threshold contrast for identifying these letters in visual noise as a function of perturbation of grating orientation, phase, and offset. We define a new measure, "wiggle", to characterize the degree to which these various perturbations violate the Gestalt law of good continuation. We find that efficiency for letter identification is inversely proportional to wiggle and is wholly determined by wiggle, independent of how the wiggle was produced. Thus the effects of three different kinds of shape perturbation on letter identifiability are predicted by a single measure of goodness of continuation. This shows that letter identification obeys the Gestalt law of good continuation and may be the first confirmation of the original Gestalt claim that object recognition involves grouping.
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Grouping in object recognition: The role of a Gestalt law in letter identification
Pelli, Denis G.; Majaj, Najib J.; Raizman, Noah; Christian, Christopher J.; Kim, Edward; Palomares, Melanie C.
2009-01-01
The Gestalt psychologists reported a set of laws describing how vision groups elements to recognize objects. The Gestalt laws “prescribe for us what we are to recognize ‘as one thing’” (Köhler, 1920). Were they right? Does object recognition involve grouping? Tests of the laws of grouping have been favourable, but mostly assessed only detection, not identification, of the compound object. The grouping of elements seen in the detection experiments with lattices and “snakes in the grass” is compelling, but falls far short of the vivid everyday experience of recognizing a familiar, meaningful, named thing, which mediates the ordinary identification of an object. Thus, after nearly a century, there is hardly any evidence that grouping plays a role in ordinary object recognition. To assess grouping in object recognition, we made letters out of grating patches and measured threshold contrast for identifying these letters in visual noise as a function of perturbation of grating orientation, phase, and offset. We define a new measure, “wiggle”, to characterize the degree to which these various perturbations violate the Gestalt law of good continuation. We find that efficiency for letter identification is inversely proportional to wiggle and is wholly determined by wiggle, independent of how the wiggle was produced. Thus the effects of three different kinds of shape perturbation on letter identifiability are predicted by a single measure of goodness of continuation. This shows that letter identification obeys the Gestalt law of good continuation and may be the first confirmation of the original Gestalt claim that object recognition involves grouping. PMID:19424881
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New genetic variants associated with prostate cancer
Researchers have newly identified 23 common genetic variants -- one-letter changes in DNA known as single-nucleotide polymorphisms or SNPs -- that are associated with risk of prostate cancer. These results come from an analysis of more than 10 million SNP
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Fifth Single-Shell Tank Integrity Project Expert Panel Meeting August 28-29, 2014
DOE Office of Scientific and Technical Information (OSTI.GOV)
Martin, Todd M.; Gunter, Jason R.; Boomer, Kayle D.
On August 28th and 29th, 2014 the Single-Shell Tank Integrity Project (SSTIP) Expert Panel (Panel) convened in Richland, Washington. This was the Panel’s first meeting since 2011 and, as a result, was focused primarily on updating the Panel on progress in response to the past recommendations (Single-Shell Tank Integrity Expert Panel Report, RPP-RPT-45921, Rev 0, May 2010). This letter documents the Panel’s discussions and feedback on Phase I activities and results.
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Origin of the defects-induced ferromagnetism in un-doped ZnO single crystals
NASA Astrophysics Data System (ADS)
Zhan, Peng; Xie, Zheng; Li, Zhengcao; Wang, Weipeng; Zhang, Zhengjun; Li, Zhuoxin; Cheng, Guodong; Zhang, Peng; Wang, Baoyi; Cao, Xingzhong
2013-02-01
We clarified, in this Letter, that in un-doped ZnO single crystals after thermal annealing in flowing argon, the defects-induced room-temperature ferromagnetism was originated from the surface defects and specifically, from singly occupied oxygen vacancies denoted as F+, by the optical and electrical properties measurements as well as positron annihilation analysis. In addition, a positive linear relationship was observed between the ferromagnetism and the F+ concentration, which is in support with the above clarification.
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Seismic Constraints on Shallow Crustal Processes at the East Pacific Rise.
1994-02-01
also put me up in his house and introduced me to the local microbreweries . Will Wilcock provided the codes for attenuation tomography used in Chapter 4...and also kept the internet busy answering all of my questions. John Collins has patiently responded to all my queries about reflectivity. Through the...Gerard Fryer. Chapter 4 is in press in Geophysical Research Letters, with co-authors Will Wilcock and G.M. Purdy. I plan on submitting a revised
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NASA Technical Reports Server (NTRS)
Kelly, Michael P.
2011-01-01
Topics covered include: Develop Program/Project Quality Assurance Surveillance Plans The work activities performed by the developer and/or his suppliers are subject to evaluation and audit by government-designated representatives. CSO supports project by selecting on-site supplier representative s by one of several methods: (1) a Defense Contract Management Agency (DCMA) person via a Letter Of Delegation (LOD), (2) an independent assurance contractor (IAC) via a contract Audits, Assessments, and Assurance (A3) Contract Code 300 Mission Assurance Support Contract (MASC)
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Program Descriptions for Interactive Signal and Pattern Analysis and Recognition System (ISPARS).
1984-03-01
procedures for the ISPARS components developed at the David Taylor Naval Ship Reserach and Development Center (DTNSRDC), which are not documented in other...an alphabetic character. Some commands may consist of a letter and one or two two-digit numbers, separated by a space as specified in the table. 81 I-I... PAPERS INTENDED FOR IN- TERNAL USE. THEY CARRY AN IDENTIFYING NUMBER WHICH INDICATES THEIR TYPE AND THE NUMERICAL CODE OF THE ORIGINATING DEPARTMENT
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Letter to the editor : Impartial review is key.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Crabtree, G. W.; Materials Science Division
The News Feature, 'Misconduct in physics: Time to wise up? [Nature 418, 120-121; 2002], raises important issues that the physical-science community must face. Argonne National Laboratory's code of ethics calls for a response very similar to that of Bell Labs, namely: 'The Laboratory director may appoint an ad-hoc scientific review committee to investigate internal or external charges of scientific misconduct, fraud, falsification of data, misinterpretation of data, or other activities involving scientific or technical matters.'
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Intersystem Interference Reduction for Overlaid HAPS-Terrestrial CDMA System
NASA Astrophysics Data System (ADS)
Huang, Jeng-Ji; Wang, Wei-Ting; Li, Mingfu; Shiung, David; Ferng, Huei-Wen
In this letter, we propose that directional antennas, combined with power management, be incorporated to reduce intersystem interference in a shared band overlaid high altitude platform station (HAPS)-terrestrial code division multiple access (CDMA) system. To eliminate the HAPS to terrestrial interference, the HAPS is accessed only via directional antennas under the proposed scheme. By doing so, the uplink power to the HAPS can accordingly be increased, so that the terrestrial to HAPS interference is also effectively suppressed.
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Too little, too late: reduced visual span and speed characterize pure alexia.
Starrfelt, Randi; Habekost, Thomas; Leff, Alexander P
2009-12-01
Whether normal word reading includes a stage of visual processing selectively dedicated to word or letter recognition is highly debated. Characterizing pure alexia, a seemingly selective disorder of reading, has been central to this debate. Two main theories claim either that 1) Pure alexia is caused by damage to a reading specific brain region in the left fusiform gyrus or 2) Pure alexia results from a general visual impairment that may particularly affect simultaneous processing of multiple items. We tested these competing theories in 4 patients with pure alexia using sensitive psychophysical measures and mathematical modeling. Recognition of single letters and digits in the central visual field was impaired in all patients. Visual apprehension span was also reduced for both letters and digits in all patients. The only cortical region lesioned across all 4 patients was the left fusiform gyrus, indicating that this region subserves a function broader than letter or word identification. We suggest that a seemingly pure disorder of reading can arise due to a general reduction of visual speed and span, and explain why this has a disproportionate impact on word reading while recognition of other visual stimuli are less obviously affected.
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Too Little, Too Late: Reduced Visual Span and Speed Characterize Pure Alexia
Habekost, Thomas; Leff, Alexander P.
2009-01-01
Whether normal word reading includes a stage of visual processing selectively dedicated to word or letter recognition is highly debated. Characterizing pure alexia, a seemingly selective disorder of reading, has been central to this debate. Two main theories claim either that 1) Pure alexia is caused by damage to a reading specific brain region in the left fusiform gyrus or 2) Pure alexia results from a general visual impairment that may particularly affect simultaneous processing of multiple items. We tested these competing theories in 4 patients with pure alexia using sensitive psychophysical measures and mathematical modeling. Recognition of single letters and digits in the central visual field was impaired in all patients. Visual apprehension span was also reduced for both letters and digits in all patients. The only cortical region lesioned across all 4 patients was the left fusiform gyrus, indicating that this region subserves a function broader than letter or word identification. We suggest that a seemingly pure disorder of reading can arise due to a general reduction of visual speed and span, and explain why this has a disproportionate impact on word reading while recognition of other visual stimuli are less obviously affected. PMID:19366870
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Accommodative performance for chromatic displays.
Lovasik, J V; Kergoat, H
1988-01-01
Over the past few years, video display units (VDUs) have been incorporated into many varieties of workplaces and occupational demands. The success of electro-optical displays in facilitating and improving job performance has spawned interest in extracting further advantage from VDUs by incorporating colour coding into such communication systems. However, concerns have been raised about the effect of chromatic stimuli on the visual comfort and task efficiency, because of the chromatic aberration inherent in the optics of the human eye. In this study, we used a computer aided laser speckle optometer system to measure the accommodative responses to brightness-matched chromatic letters displayed on a high-resolution RGB monitor. Twenty, visually normal, paid volunteers in a 22-35 year age category served as subjects. Stimuli were 14, 21, 28 minutes of arc letters presented in a 'monochromatic' (white, red, green or blue, on a black background) or 'multichromatic' (blue-red, blue-green, red-green, foreground-background combinations) mode at 40 and 80 cm viewing distances. The results demonstrated that while the accommodative responses were strongly influenced by the foreground-background colour combination, the group-averaged dioptric difference across colours was relatively small. Further, accommodative responses were not guided in any systematic fashion by the size of letters presented for fixation. Implications of these findings for display designs are discussed.
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75 FR 5236 - New Postal Product
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-02
... Description] Premium Stamped Stationery [Reserved for Product Description] Premium Stamped Cards [Reserved for... determine whether such an agreement (1) Improves the net financial position of the Postal Service or... Descriptions First-Class Mail [Reserved for Class Description] Single-Piece Letters/Postcards [Reserved for...
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Single-shot speckle reduction in numerical reconstruction of digitally recorded holograms: comment.
Maycock, Jonathan; Hennelly, Bryan; McDonald, John
2015-09-01
We comment on a recent Letter by Hincapie et al. [Opt. Lett.40, 1623 (2015)], in which the authors proposed a method to reduce the speckle noise in digital holograms. This method was previously published by us in Maycock ["Improving reconstructions of digital holograms," Ph.D. thesis (National University of Ireland, 2012)] and Maycock and Hennelly [Improving Reconstructions of Digital Holograms: Speckle Reduction and Occlusions in Digital Holography (Lambert Academic, 2014)]. We also wish to highlight an important limitation of the method resulting from the superposition of different perspectives of the object/scene, which was not addressed in their Letter.
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Letter-case information and the identification of brand names.
Perea, Manuel; Jiménez, María; Talero, Fernanda; López-Cañada, Soraya
2015-02-01
A central tenet of most current models of visual-word recognition is that lexical units are activated on the basis of case-invariant abstract letter representations. Here, we examined this assumption by using a unique type of words: brand names. The rationale of the experiments is that brand names are archetypically printed either in lowercase (e.g., adidas) or uppercase (e.g., IKEA). This allows us to present the brand names in their standard or non-standard case configuration (e.g., adidas, IKEA vs. ADIDAS, ikea, respectively). We conducted two experiments with a brand-decision task ('is it a brand name?'): a single-presentation experiment and a masked priming experiment. Results in the single-presentation experiment revealed faster identification times of brand names in their standard case configuration than in their non-standard case configuration (i.e., adidas faster than ADIDAS; IKEA faster than ikea). In the masked priming experiment, we found faster identification times of brand names when they were preceded by an identity prime that matched its standard case configuration than when it did not (i.e., faster response times to adidas-adidas than to ADIDAS-adidas). Taken together, the present findings strongly suggest that letter-case information forms part of a brand name's graphemic information, thus posing some limits to current models of visual-word recognition. © 2014 The British Psychological Society.
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Materials science: Crystals aligned through graphene
NASA Astrophysics Data System (ADS)
Lee, Minjoo Larry
2017-04-01
Graphene has been used as a 'transparent' layer that allows single crystals of a material to be grown on a substrate, and then lifted off -- in much the same way that baking paper lets cakes be removed easily from tins. See Letter p.340
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An Open Letter to the Cancer Community Regarding Community Clinical Trials
The National Cancer Institute (NCI) is in the process of combining its two community-based research networks to create a single network that builds on the strengths of the Community Clinical Oncology Program/Minority-Based Community Clinical Oncology Prog
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The Mismatch between Assessment and Grading.
ERIC Educational Resources Information Center
Seeley, Marcia M.
1994-01-01
Teachers are receiving mixed messages about assessment. Encouraged to use alternative assessment practices, they are expected to express a student's progress in a single letter grade. Interviews with eight urban middle school teachers participating in the QUASAR (Quantitative Understanding: Amplifying Student Achievement and Reasoning) Project…
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Informational structure of genetic sequences and nature of gene splicing
NASA Astrophysics Data System (ADS)
Trifonov, E. N.
1991-10-01
Only about 1/20 of DNA of higher organisms codes for proteins, by means of classical triplet code. The rest of DNA sequences is largely silent, with unclear functions, if any. The triplet code is not the only code (message) carried by the sequences. There are three levels of molecular communication, where the same sequence ``talks'' to various bimolecules, while having, respectively, three different appearances: DNA, RNA and protein. Since the molecular structures and, hence, sequence specific preferences of these are substantially different, the original DNA sequence has to carry simultaneously three types of sequence patterns (codes, messages), thus, being a composite structure in which one had the same letter (nucleotide) is frequently involved in several overlapping codes of different nature. This multiplicity and overlapping of the codes is a unique feature of the Gnomic, language of genetic sequences. The coexisting codes have to be degenerate in various degrees to allow an optimal and concerted performance of all the encoded functions. There is an obvious conflict between the best possible performance of a given function and necessity to compromise the quality of a given sequence pattern in favor of other patterns. It appears that the major role of various changes in the sequences on their ``ontogenetic'' way from DNA to RNA to protein, like RNA editing and splicing, or protein post-translational modifications is to resolve such conflicts. New data are presented strongly indicating that the gene splicing is such a device to resolve the conflict between the code of DNA folding in chromatin and the triplet code for protein synthesis.
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A Comparison of Two Chord Keyboard Coding Systems for Alphanumeric Data Entry.
1987-06-01
These rates were achieved while typing new material with no more than two errors per minute. No IBM machine has yet been marketed using this chord...type", subject’s typing rates on the standard typewriter ranged from 54.5 CPM to 176.5 CPM for mixed alphanumeric data. Nine of the ten subjects...dot Keyboard and the Standard Keyboard Material Keyboard Entry Rate All Letters Alpha-dot Keyboard 65.25 CPM Mixed Alpha/Numeric Text Alpha-dot
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An Interactive Activation Model of the Effect of Context in Perception. Part 2
1980-07-15
nonword strings are often seen with letters transposed if the transposition will produce legal strings (Estes, 1975a; c.f. experiment by Stevens reported...Activation Model Rumelhart & McClelland Part II 90 References Anderson, J. A. Neural models with cognitive implications. In D. LaBerge & S. J. Samuels...Washington, DC 20372 Coe391 Dr. Gory PoockNavy Personnel R&D Center Operations Research Department LT Steven D. Harris. MSC, USN San Diego, CA 92152 Code
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1980-03-01
Oceanography Center (FNOC) is currently testing and evaluating a computerized flight plan system, referred to, for short, as OPARS. This sytem , developed to...replace the Lockheed Jetplan flight plan sytem , provides users at remote sites with direct access to the FNOC computer via 11 telephone lines. The...validity, but only for format. For example, an entry of ABCE , as the four- letter identification code for the destination airfield, would be accepted
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1979-04-17
i I tie frlr. o, -J*:, i io s )r *i r -is 1 :1 iv 71 1, q. Q’ " n -’ d to - ’ln t i: s ’I osl o SA A~S: 11,0% unid-rs! n d i of ?rint, d c ,,.I tt...readings off dosimeter Coordinate scales Callsigns-suffices Three-letter codes Exmples Calculations Markings Radio comunications Range cards Notes Messages V
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Wong, Ngo Yin; Xing, Hang; Tan, Li Huey; Lu, Yi
2013-02-27
While much work has been devoted to nanoscale assembly of functional materials, selective reversible assembly of components in the nanoscale pattern at selective sites has received much less attention. Exerting such a reversible control of the assembly process will make it possible to fine-tune the functional properties of the assembly and to realize more complex designs. Herein, by taking advantage of different binding affinities of biotin and desthiobiotin toward streptavidin, we demonstrate selective and reversible decoration of DNA origami tiles with streptavidin, including revealing an encrypted Morse code "NANO" and reversible exchange of uppercase letter "I" with lowercase "i". The yields of the conjugations are high (>90%), and the process is reversible. We expect this versatile conjugation technique to be widely applicable with different nanomaterials and templates.
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Li, Ying
2016-09-16
Fault-tolerant quantum computing in systems composed of both Majorana fermions and topologically unprotected quantum systems, e.g., superconducting circuits or quantum dots, is studied in this Letter. Errors caused by topologically unprotected quantum systems need to be corrected with error-correction schemes, for instance, the surface code. We find that the error-correction performance of such a hybrid topological quantum computer is not superior to a normal quantum computer unless the topological charge of Majorana fermions is insusceptible to noise. If errors changing the topological charge are rare, the fault-tolerance threshold is much higher than the threshold of a normal quantum computer and a surface-code logical qubit could be encoded in only tens of topological qubits instead of about 1,000 normal qubits.
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RNA-protein interactions in an unstructured context.
Zagrovic, Bojan; Bartonek, Lukas; Polyansky, Anton A
2018-05-31
Despite their importance, our understanding of noncovalent RNA-protein interactions is incomplete. This especially concerns the binding between RNA and unstructured protein regions, a widespread class of such interactions. Here, we review the recent experimental and computational work on RNA-protein interactions in an unstructured context with a particular focus on how such interactions may be shaped by the intrinsic interaction affinities between individual nucleobases and protein side chains. Specifically, we articulate the claim that the universal genetic code reflects the binding specificity between nucleobases and protein side chains and that, in turn, the code may be seen as the Rosetta stone for understanding RNA-protein interactions in general. © 2018 The Authors. FEBS Letters published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.
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Unique sudden onsets capture attention even when observers are in feature-search mode.
Spalek, Thomas M; Yanko, Matthew R; Poiese, Paola; Lagroix, Hayley E P
2012-01-01
Two sources of attentional capture have been proposed: stimulus-driven (exogenous) and goal-oriented (endogenous). A resolution between these modes of capture has not been straightforward. Even such a clearly exogenous event as the sudden onset of a stimulus can be said to capture attention endogenously if observers operate in singleton-detection mode rather than feature-search mode. In four experiments we show that a unique sudden onset captures attention even when observers are in feature-search mode. The displays were rapid serial visual presentation (RSVP) streams of differently coloured letters with the target letter defined by a specific colour. Distractors were four #s, one of the target colour, surrounding one of the non-target letters. Capture was substantially reduced when the onset of the distractor array was not unique because it was preceded by other sets of four grey # arrays in the RSVP stream. This provides unambiguous evidence that attention can be captured both exogenously and endogenously within a single task.
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7 CFR 1775.12 - Grant processing.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 12 2010-01-01 2010-01-01 false Grant processing. 1775.12 Section 1775.12 Agriculture... (CONTINUED) TECHNICAL ASSISTANCE GRANTS Grant Application Processing § 1775.12 Grant processing. (a) Single State applications. (1) Grant applications submitted at the State level will receive a letter...
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USDA-ARS?s Scientific Manuscript database
We appreciate the opportunity to respond to the letter from Dr. Krawinkel regarding our recent publication on the vitamin A equivalency of Golden Rice. In this study we utilized stable isotope methodologies and a single serving (per subject) of Golden Rice (a transgenic rice that produces beta-caro...
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Three-dimensional time reversal communications in elastic media
Anderson, Brian E.; Ulrich, Timothy J.; Le Bas, Pierre-Yves; ...
2016-02-23
Our letter presents a series of vibrational communication experiments, using time reversal, conducted on a set of cast iron pipes. Time reversal has been used to provide robust, private, and clean communications in many underwater acoustic applications. Also, the use of time reversal to communicate along sections of pipes and through a wall is demonstrated here in order to overcome the complications of dispersion and multiple scattering. These demonstrations utilize a single source transducer and a single sensor, a triaxial accelerometer, enabling multiple channels of simultaneous communication streams to a single location.
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NASA Astrophysics Data System (ADS)
Baraffe, I.; Pratt, J.; Goffrey, T.; Constantino, T.; Folini, D.; Popov, M. V.; Walder, R.; Viallet, M.
2017-08-01
We study lithium depletion in low-mass and solar-like stars as a function of time, using a new diffusion coefficient describing extra-mixing taking place at the bottom of a convective envelope. This new form is motivated by multi-dimensional fully compressible, time-implicit hydrodynamic simulations performed with the MUSIC code. Intermittent convective mixing at the convective boundary in a star can be modeled using extreme value theory, a statistical analysis frequently used for finance, meteorology, and environmental science. In this Letter, we implement this statistical diffusion coefficient in a one-dimensional stellar evolution code, using parameters calibrated from multi-dimensional hydrodynamic simulations of a young low-mass star. We propose a new scenario that can explain observations of the surface abundance of lithium in the Sun and in clusters covering a wide range of ages, from ˜50 Myr to ˜4 Gyr. Because it relies on our physical model of convective penetration, this scenario has a limited number of assumptions. It can explain the observed trend between rotation and depletion, based on a single additional assumption, namely, that rotation affects the mixing efficiency at the convective boundary. We suggest the existence of a threshold in stellar rotation rate above which rotation strongly prevents the vertical penetration of plumes and below which rotation has small effects. In addition to providing a possible explanation for the long-standing problem of lithium depletion in pre-main-sequence and main-sequence stars, the strength of our scenario is that its basic assumptions can be tested by future hydrodynamic simulations.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Baraffe, I.; Pratt, J.; Goffrey, T.
We study lithium depletion in low-mass and solar-like stars as a function of time, using a new diffusion coefficient describing extra-mixing taking place at the bottom of a convective envelope. This new form is motivated by multi-dimensional fully compressible, time-implicit hydrodynamic simulations performed with the MUSIC code. Intermittent convective mixing at the convective boundary in a star can be modeled using extreme value theory, a statistical analysis frequently used for finance, meteorology, and environmental science. In this Letter, we implement this statistical diffusion coefficient in a one-dimensional stellar evolution code, using parameters calibrated from multi-dimensional hydrodynamic simulations of a youngmore » low-mass star. We propose a new scenario that can explain observations of the surface abundance of lithium in the Sun and in clusters covering a wide range of ages, from ∼50 Myr to ∼4 Gyr. Because it relies on our physical model of convective penetration, this scenario has a limited number of assumptions. It can explain the observed trend between rotation and depletion, based on a single additional assumption, namely, that rotation affects the mixing efficiency at the convective boundary. We suggest the existence of a threshold in stellar rotation rate above which rotation strongly prevents the vertical penetration of plumes and below which rotation has small effects. In addition to providing a possible explanation for the long-standing problem of lithium depletion in pre-main-sequence and main-sequence stars, the strength of our scenario is that its basic assumptions can be tested by future hydrodynamic simulations.« less
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Targeting the prostate for destruction through a vascular address
Arap, Wadih; Haedicke, Wolfgang; Bernasconi, Michele; Kain, Renate; Rajotte, Daniel; Krajewski, Stanislaw; Ellerby, H. Michael; Bredesen, Dale E.; Pasqualini, Renata; Ruoslahti, Erkki
2002-01-01
Organ specific drug targeting was explored in mice as a possible alternative to surgery to treat prostate diseases. Peptides that specifically recognize the vasculature in the prostate were identified from phage-displayed peptide libraries by selecting for phage capable of homing into the prostate after an i.v. injection. One of the phage selected in this manner homed to the prostate 10–15 times more than to other organs. Unselected phage did not show this preference. The phage bound also to vasculature in the human prostate. The peptide displayed by the prostate-homing phage, SMSIARL (single letter code), was synthesized and shown to inhibit the homing of the phage when co-injected into mice with the phage. Systemic treatment of mice with a chimeric peptide consisting of the SMSIARL homing peptide, linked to a proapoptotic peptide that disrupts mitochondrial membranes, caused tissue destruction in the prostate, but not in other organs. The chimeric peptide delayed the development of the cancers in prostate cancer-prone transgenic mice (TRAMP mice). These results suggest that it may be possible to develop an alternative to surgical prostate resection and that such a treatment may also reduce future cancer risk. PMID:11830668
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The Left Occipitotemporal Cortex Does Not Show Preferential Activity for Words
Petersen, Steven E.; Schlaggar, Bradley L.
2012-01-01
Regions in left occipitotemporal (OT) cortex, including the putative visual word form area, are among the most commonly activated in imaging studies of single-word reading. It remains unclear whether this part of the brain is more precisely characterized as specialized for words and/or letters or contains more general-use visual regions having properties useful for processing word stimuli, among others. In Analysis 1, we found no evidence of greater activity in left OT regions for words or letter strings relative to other high–spatial frequency high-contrast stimuli, including line drawings and Amharic strings (which constitute the Ethiopian writing system). In Analysis 2, we further investigated processing characteristics of OT cortex potentially useful in reading. Analysis 2 showed that a specific part of OT cortex 1) is responsive to visual feature complexity, measured by the number of strokes forming groups of letters or Amharic strings and 2) processes learned combinations of characters, such as those in words and pseudowords, as groups but does not do so in consonant and Amharic strings. Together, these results indicate that while regions of left OT cortex are not specialized for words, at least part of OT cortex has properties particularly useful for processing words and letters. PMID:22235035
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Computer Processing of Esperanto Text.
ERIC Educational Resources Information Center
Sherwood, Bruce
1981-01-01
Basic aspects of computer processing of Esperanto are considered in relation to orthography and computer representation, phonetics, morphology, one-syllable and multisyllable words, lexicon, semantics, and syntax. There are 28 phonemes in Esperanto, each represented in orthography by a single letter. The PLATO system handles diacritics by using a…
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Pollatsek, Alexander; Perea, Manuel; Carreiras, Manuel
2005-04-01
Evidence for an early involvement of phonology in word identification usually relies on the comparison between a target word preceded by a homophonic prime and an orthographic control (rait-RATE vs. raut-RATE). This comparison rests on the assumption that the two control primes are equally orthographically similar to the target. Here, we tested for phonological effects with a masked priming paradigm in which orthographic similarity between priming conditions was perfectly controlled at the letter level and in which identification of the prime was virtually at chance for both stimulus onset asynchronies (SOAs) (66 and 50 msec). In the key prime-target pairs, each prime differed from the target by one vowel letter, but one changed the sound of the initial c, and the other did not (cinal-CANAL vs. conal-CANAL). In the control prime-target pairs, the primes had the identical vowel manipulation, but neither changed the initial consonant sound (pinel-PANEL vs. ponel-PANEL). For both high- and low-frequency words, lexical decision responses to the target were slower when the prime changed the sound of the c than when it did not, whereas there was no difference for the controls at both SOAs. However, this phonological effect was small and was not significant when the SOA was 50 msec. The pattern of data is consistent with an early phonological coding of primes that occurs just a little later than orthographic coding.
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Lee, Joseph G L; Baker, Hannah M; Ranney, Leah M; Goldstein, Adam O
2015-10-08
Retailer noncompliance with limited US tobacco regulations on advertising and labeling was historically patterned by neighborhood in ways that promote health disparities. In 2010, the US Food and Drug Administration (FDA) began enforcing stronger tobacco retailer regulations under the Family Smoking Prevention and Tobacco Control Act of 2009. However, recent research has found no differences in compliance by neighborhood characteristics for FDA advertising and labeling inspections. We sought to investigate the neighborhood characteristics associated with retailer noncompliance with specific FDA advertising and labeling inspections (ie, violations of bans on self-service displays, selling single cigarettes, false or mislabeled products, vending machines, flavored cigarettes, and free samples). We coded FDA advertising and labeling warning letters (n = 718) for type of violations and geocoded advertising and labeling inspections from January 1 through July 31, 2014 (N = 33,543). Using multilevel models, we examined cross-sectional associations between types of violations and neighborhood characteristics previously associated with disparities (ie, percentage black, Latino, under the poverty line, and younger than 18 years). Retailer advertising and labeling violations are patterned by who lives in the neighborhood; regulated tobacco products are more likely to be stored behind the counter as the percentage of black or Latino residents increases, and single cigarettes are more often available for purchase in neighborhoods as the percentage of black, poor, or young residents increases. Contrary to previous null findings, noncompliance with FDA advertising and labeling regulations is patterned by neighborhood characteristics, sometimes in opposite directions. Given the low likelihood of self-service violations in the same neighborhoods that have high likelihood of single cigarette sales, we suggest targeted approaches to FDA retailer inspections and education campaigns.
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Baker, Hannah M.; Ranney, Leah M.; Goldstein, Adam O.
2015-01-01
Introduction Retailer noncompliance with limited US tobacco regulations on advertising and labeling was historically patterned by neighborhood in ways that promote health disparities. In 2010, the US Food and Drug Administration (FDA) began enforcing stronger tobacco retailer regulations under the Family Smoking Prevention and Tobacco Control Act of 2009. However, recent research has found no differences in compliance by neighborhood characteristics for FDA advertising and labeling inspections. We sought to investigate the neighborhood characteristics associated with retailer noncompliance with specific FDA advertising and labeling inspections (ie, violations of bans on self-service displays, selling single cigarettes, false or mislabeled products, vending machines, flavored cigarettes, and free samples). Methods We coded FDA advertising and labeling warning letters (n = 718) for type of violations and geocoded advertising and labeling inspections from January 1 through July 31, 2014 (N = 33,543). Using multilevel models, we examined cross-sectional associations between types of violations and neighborhood characteristics previously associated with disparities (ie, percentage black, Latino, under the poverty line, and younger than 18 years). Results Retailer advertising and labeling violations are patterned by who lives in the neighborhood; regulated tobacco products are more likely to be stored behind the counter as the percentage of black or Latino residents increases, and single cigarettes are more often available for purchase in neighborhoods as the percentage of black, poor, or young residents increases. Conclusion Contrary to previous null findings, noncompliance with FDA advertising and labeling regulations is patterned by neighborhood characteristics, sometimes in opposite directions. Given the low likelihood of self-service violations in the same neighborhoods that have high likelihood of single cigarette sales, we suggest targeted approaches to FDA retailer inspections and education campaigns. PMID:26447548
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Code of Federal Regulations, 2010 CFR
2010-04-01
... 25 Indians 1 2010-04-01 2010-04-01 false May a tribe create and adopt a single heir rule without adopting a tribal probate code? 18.301 Section 18.301 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR PROBATE TRIBAL PROBATE CODES Approval of Single Heir Rule § 18.301 May a tribe create and adopt a...
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Single-Particle Mobility Edge in a One-Dimensional Quasiperiodic Optical Lattice
NASA Astrophysics Data System (ADS)
Lüschen, Henrik P.; Scherg, Sebastian; Kohlert, Thomas; Schreiber, Michael; Bordia, Pranjal; Li, Xiao; Das Sarma, S.; Bloch, Immanuel
2018-04-01
A single-particle mobility edge (SPME) marks a critical energy separating extended from localized states in a quantum system. In one-dimensional systems with uncorrelated disorder, a SPME cannot exist, since all single-particle states localize for arbitrarily weak disorder strengths. However, in a quasiperiodic system, the localization transition can occur at a finite detuning strength and SPMEs become possible. In this Letter, we find experimental evidence for the existence of such a SPME in a one-dimensional quasiperiodic optical lattice. Specifically, we find a regime where extended and localized single-particle states coexist, in good agreement with theoretical simulations, which predict a SPME in this regime.
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Random breakup of microdroplets for single-cell encapsulation
NASA Astrophysics Data System (ADS)
Um, Eujin; Lee, Seung-Goo; Park, Je-Kyun
2010-10-01
Microfluidic droplet-based technology enables encapsulation of cells in the isolated aqueous chambers surrounded by immiscible fluid but single-cell encapsulation efficiency is usually less than 30%. In this letter, we introduce a simple microgroove structure to break droplets into random sizes which further allows collecting of single-cell [Escherichia coli (E. coli)] containing droplets by their size differences. Pinched-flow separation method is integrated to sort out droplets of certain sizes which have high probability of containing one cell. Consequently, we were able to obtain more than 50% of droplets having single E. coli inside, keeping the proportion of multiple-cell containing droplets less than 16%.
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CARES/LIFE Software Commercialization
NASA Technical Reports Server (NTRS)
1995-01-01
The NASA Lewis Research Center has entered into a letter agreement with BIOSYM Technologies Inc. (now merged with Molecular Simulations Inc. (MSI)). Under this agreement, NASA will provide a developmental copy of the CARES/LIFE computer program to BIOSYM for evaluation. This computer code predicts the time-dependent reliability of a thermomechanically loaded component. BIOSYM will become familiar with CARES/LIFE, provide results of computations useful in validating the code, evaluate it for potential commercialization, and submit suggestions for improvements or extensions to the code or its documentation. If BIOSYM/Molecular Simulations reaches a favorable evaluation of CARES/LIFE, NASA will enter into negotiations for a cooperative agreement with BIOSYM/Molecular Simulations to further develop the code--adding features such as a user-friendly interface and other improvements. This agreement would give BIOSYM intellectual property rights in the modified codes, which they could protect and then commercialize. NASA would provide BIOSYM with the NASA-developed source codes and would agree to cooperate with BIOSYM in further developing the code. In return, NASA would receive certain use rights in the modified CARES/LIFE program. Presently BIOSYM Technologies Inc. has been involved with integration issues concerning its merger with Molecular Simulations Inc., since both companies used to compete in the computational chemistry market, and to some degree, in the materials market. Consequently, evaluation of the CARES/LIFE software is on hold for a month or two while the merger is finalized. Their interest in CARES continues, however, and they expect to get back to the evaluation by early November 1995.
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Simultaneous RGB lasing from a single-chip polymer device.
Yamashita, Kenichi; Takeuchi, Nobutaka; Oe, Kunishige; Yanagi, Hisao
2010-07-15
This Letter describes the fabrication and operation of a single-chip white-laser device. The laser device has a multilayered structure consisting of three laser layers. Each laser layer comprises polymer claddings and a waveguide core doped with organic dye. In each laser layer, grating corrugations were fabricated by UV-nanoimprint lithography that act as distributed-feedback cavity structures. Under optical pumping, lasing output with red, green, and blue colors was simultaneously obtained from the sample edge.
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Patient preferences for partner notification.
Apoola, A; Radcliffe, K W; Das, S; Robshaw, V; Gilleran, G; Kumari, B S; Boothby, M; Rajakumar, R
2006-08-01
To identify patient preferences for notification of sexual contacts when a sexually transmitted infection (STI) is diagnosed. A questionnaire survey of 2544 patients attending three large genitourinary clinics at Derby, Birmingham, and Coventry in the United Kingdom. The median age of the respondents was 24 with 1474 (57.9%) women, 1835 (72.1%) white, 1826 (71.8%) single. The most favoured method of partner notification was patient referral, which was rated a "good" method by 65.8% when they had to be contacted because a sexual partner has an STI. Notifying contacts by letter as a method of provider partner notification is more acceptable than phoning, text messaging, or email. Respondents with access to mobile telephones, private emails, and private letters were more likely to rate a method of partner notification using that mode of communication as "good" compared to those without. With provider referral methods of partner notification respondents preferred to receive a letter, email, or text message asking them to contact the clinic rather than a letter, email or text message informing them that they may have an STI. Most respondents think that being informed directly by a partner is the best method of being notified of the risk of an STI. Some of the newer methods may not be acceptable to all but a significant minority of respondents prefer these methods of partner notification. The wording of letters, emails, or text messages when used for partner notification has an influence on the acceptability of the method and may influence success of the partner notification method. Services should be flexible enough to utilise the patients' preferred method of partner notification.
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Braun, Mischa; Weinrich, Christiane; Finke, Carsten; Ostendorf, Florian; Lehmann, Thomas-Nicolas; Ploner, Christoph J
2011-03-01
Converging evidence from behavioral and imaging studies suggests that within the human medial temporal lobe (MTL) the hippocampal formation may be particularly involved in recognition memory of associative information. However, it is unclear whether the hippocampal formation processes all types of associations or whether there is a specialization for processing of associations involving spatial information. Here, we investigated this issue in six patients with postsurgical lesions of the right MTL affecting the hippocampal formation and in ten healthy controls. Subjects performed a battery of delayed match-to-sample tasks with two delays (900/5,000 ms) and three set sizes. Subjects were requested to remember either single features (colors, locations, shapes, letters) or feature associations (color-location, color-shape, color-letter). In the single-feature conditions, performance of patients did not differ from controls. In the association conditions, a significant delay-dependent deficit in memory of color-location associations was found. This deficit was largely independent of set size. By contrast, performance in the color-shape and color-letter conditions was normal. These findings support the hypothesis that a region within the right MTL, presumably the hippocampal formation, does not equally support all kinds of visual memory but rather has a bias for processing of associations involving spatial information. Recruitment of this region during memory tasks appears to depend both on processing type (associative/nonassociative) and to-be-remembered material (spatial/nonspatial). Copyright © 2010 Wiley-Liss, Inc.
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One Approach to Teaching the Specific Language Disabled Adult Language Arts.
ERIC Educational Resources Information Center
Peterson, Binnie L.
1981-01-01
One approach never before used in adult language arts instruction--the Slingerland Simultaneous Multisensory Technique--has been found useful for specific language disabled adults in multisensory programs at Anchorage Community College. The Slingerland method builds from single sight, sound, and feel of letters through combinations, encoding,…
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2012-06-01
this report. The property measurements that have been focused on were the assessment of density ( Archimedes ). grain structure {optical and SEM...Scintillator", Materials Letters 60 1960-1963 (2006) [15] J.S. Reed, Forming Processes, Chapter 20 in Introduction to the Principles of Ceramic
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Abstract Graphemic Representations Support Preparation of Handwritten Responses
ERIC Educational Resources Information Center
Shen, Xingjia Rachel; Damian, Marcus F.; Stadthagen-Gonzalez, Hans
2013-01-01
Some evidence suggests that the written production of single words involves not only the ordered retrieval of individual letters, but that abstract, higher-level linguistic properties of the words also influence responses. We report five experiments using the "implicit priming" task adopted from the spoken domain to investigate response…
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Basic Processes in Reading: The Effect of Interletter Spacing
ERIC Educational Resources Information Center
Risko, Evan F.; Lanthier, Sophie N.; Besner, Derek
2011-01-01
Reading is acutely sensitive to the amount of space between letters within a string. In the present investigation, we explore the impairment caused by increasing interletter spacing when reading single words and nonwords aloud. Specifically, 2 hypotheses are tested: (a) whether increasing interletter spacing induces serial processing while reading…
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Wong, Ngo Yin; Xing, Hang; Tan, Li Huey; Lu, Yi
2013-01-01
While much work has been devoted to nanoscale assembly of functional materials, selective reversible assembly of components in the nanoscale pattern at selective sites has received much less attention. Exerting such a reversible control of the assembly process will make it possible to fine-tune the functional properties of the assembly and to realize more complex designs. Herein, by taking advantage of different binding affinities of biotin and desthiobiotin toward streptavidin, we demonstrate selective and reversible decoration of DNA origami tiles with streptavidin, including revealing an encrypted Morse code “NANO” and reversible exchange of uppercase letter “I” with lowercase “i”. The yields of the conjugations are high (> 90%) and the process is reversible. We expect this versatile conjugation technique to be widely applicable with different nanomaterials and templates. PMID:23373425
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Neely, J. R.; Hornung, R.; Black, A.
This document serves as a detailed companion to the powerpoint slides presented as part of the ASC L2 milestone review for Integrated Codes milestone #4782 titled “Assess Newly Emerging Programming and Memory Models for Advanced Architectures on Integrated Codes”, due on 9/30/2014, and presented for formal program review on 9/12/2014. The program review committee is represented by Mike Zika (A Program Project Lead for Kull), Brian Pudliner (B Program Project Lead for Ares), Scott Futral (DEG Group Lead in LC), and Mike Glass (Sierra Project Lead at Sandia). This document, along with the presentation materials, and a letter of completionmore » signed by the review committee will act as proof of completion for this milestone.« less
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Randomized controlled trial of a dose consolidation program.
Delate, Thomas; Fairman, Kathleen A; Carey, Shelly M; Motheral, Brenda R
2004-01-01
To evaluate the effectiveness and financial impact of a drug dose consolidation (optimization) program using letter intervention. This pilot program in a large, mid-Atlantic health plan utilized a randomized controlled trial research design. A review of adjudicated pharmacy claims records was performed monthly for 3 consecutive months from November 2002 through February 2003 to identify inefficient (i.e., >once-daily) regimens for any one of 68 dosage strengths of 37 single-source maintenance drugs with once-daily dosing recommendations. Prescribers who had prescribed one or more inefficient regimens were identified and randomized to one of the 2 intervention arms or a control arm. Prescribers in both intervention arms were sent personalized letters with information on their patients. inefficient regimens and suggested dose consolidation options. Patients of prescribers in one intervention arm received a complementary, patient-oriented letter. Pharmacy claims for patients in all arms were examined at 180 days after the date of the letter mailing for conversion to an efficient (once-daily) regimen. Financial modeling analysis calculated net savings as changes in pharmacy expenditures minus administrative costs. A total of 2,614 inefficient regimens, representing 6.7% of claims for the targeted medications, were identified. The rate of consolidation to a suggested dosing option was lower for the Physician Letter arm (7.3%) than for the Physician/Member Letter arm (10.2%) (P = 0.046). Both intervention arms had higher consolidation rates than the Control arm (3.9%) (P = 0.018 and P = 0.000, respectively.). Approximately 30% of the regimens in each study arm were never refilled after being targeted. Financial modeling indicated that a dose consolidation intervention could save 0.03 dollars to 0.07 dollars per member per month (PMPM) in 2003 dollars with full medication compliance but only 0.02 dollars to 0.03 dollars PMPM when savings were calculated with realistic, partial compliance rates. Subanalyses performed at the drug therapy class level revealed few opportunities to justify implementing a dose consolidation program. After taking into consideration program administrative costs, high rates of refill discontinuation, and dose consolidation that occurs naturally without intervention, the results indicated that a letter-based dose consolidation program did not appreciably decrease pharmacy expenditures.
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The Coast Artillery Journal. Volume 56, Number 6, June 1922
1922-06-01
lay-June, 1922. Le fonctionnement des services a l’interieur de la D. A. (IV).-Be-4, ::\\lay, 1922. Ligeros Apuntes Sobre la Instruccion de Planas...34 which is contained in paragraph 101 to 105,both inclusive . As the items we have considered so far would not occupy a half- hour’s drill period let us...two-arm SemaPhore Code. 1 Letters A-G inclusive . Note that in this course the let- 2 A-H, Z. ters are grouped as nearly as 3 A-I, X, Z. possible with
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2015-07-09
49, pp. 873-885, Apr. 2003. [23] G. N. Karystinos and D. A. Pados, “New bounds on the total squared correlation and optimum design of DS - CDMA binary...bounds on DS - CDMA binary signature sets,” Designs, Codes and Cryptography, vol. 30, pp. 73-84, Aug. 2003. [25] V. P. Ipatov, “On the Karystinos-Pados...bounds and optimal binary DS - CDMA signature ensembles,” IEEE Commun. Letters, vol. 8, pp. 81-83, Feb. 2004. [26] G. N. Karystinos and D. A. Pados
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ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. House Committee on Education and Labor.
This is a Congressional hearing to review and receive comment on H.R. 6190, legislation that would amend Title 38, United States Code, to exempt GI bill educational benefits from the determination of a veteran's eligibility for Federal educational benefits. Testimony includes statements, prepared statements, letters, and supplemental materials…
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Frassinetti, L; Predebon, I; Koguchi, H; Yagi, Y; Hirano, Y; Sakakita, H; Spizzo, G; White, R B
2006-10-27
The quasi-single-helicity (QSH) state of a reversed-field pinch (RFP) plasma is a regime in which the RFP configuration can be sustained by a dynamo produced mainly by a single tearing mode and in which a helical structure with well-defined magnetic flux surfaces arises. In this Letter, we show that spontaneous transitions to the QSH regime enhance the particle confinement. This improvement is originated by the simultaneous and cooperative action of the increase of the magnetic island and the reduction of the magnetic stochasticity.
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Coding stimulus amplitude by correlated neural activity
NASA Astrophysics Data System (ADS)
Metzen, Michael G.; Ávila-Åkerberg, Oscar; Chacron, Maurice J.
2015-04-01
While correlated activity is observed ubiquitously in the brain, its role in neural coding has remained controversial. Recent experimental results have demonstrated that correlated but not single-neuron activity can encode the detailed time course of the instantaneous amplitude (i.e., envelope) of a stimulus. These have furthermore demonstrated that such coding required and was optimal for a nonzero level of neural variability. However, a theoretical understanding of these results is still lacking. Here we provide a comprehensive theoretical framework explaining these experimental findings. Specifically, we use linear response theory to derive an expression relating the correlation coefficient to the instantaneous stimulus amplitude, which takes into account key single-neuron properties such as firing rate and variability as quantified by the coefficient of variation. The theoretical prediction was in excellent agreement with numerical simulations of various integrate-and-fire type neuron models for various parameter values. Further, we demonstrate a form of stochastic resonance as optimal coding of stimulus variance by correlated activity occurs for a nonzero value of noise intensity. Thus, our results provide a theoretical explanation of the phenomenon by which correlated but not single-neuron activity can code for stimulus amplitude and how key single-neuron properties such as firing rate and variability influence such coding. Correlation coding by correlated but not single-neuron activity is thus predicted to be a ubiquitous feature of sensory processing for neurons responding to weak input.
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Augmented burst-error correction for UNICON laser memory. [digital memory
NASA Technical Reports Server (NTRS)
Lim, R. S.
1974-01-01
A single-burst-error correction system is described for data stored in the UNICON laser memory. In the proposed system, a long fire code with code length n greater than 16,768 bits was used as an outer code to augment an existing inner shorter fire code for burst error corrections. The inner fire code is a (80,64) code shortened from the (630,614) code, and it is used to correct a single-burst-error on a per-word basis with burst length b less than or equal to 6. The outer code, with b less than or equal to 12, would be used to correct a single-burst-error on a per-page basis, where a page consists of 512 32-bit words. In the proposed system, the encoding and error detection processes are implemented by hardware. A minicomputer, currently used as a UNICON memory management processor, is used on a time-demanding basis for error correction. Based upon existing error statistics, this combination of an inner code and an outer code would enable the UNICON system to obtain a very low error rate in spite of flaws affecting the recorded data.
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Experimental demonstration of a single-spike hard-X-ray free-electron laser starting from noise
Marinelli, A.; MacArthur, J.; Emma, P.; ...
2017-10-09
In this letter, we report the experimental demonstration of single-spike hard-X-ray free-electron laser pulses starting from noise with multi-eV bandwidth. Here, this is accomplished by shaping a low-charge electron beam with a slotted emittance spoiler and by adjusting the transport optics to optimize the beam-shaping accuracy. Based on elementary free-electron laser scaling laws, we estimate the pulse duration to be less than 1 fs full-width at half-maximum.
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Mitri, F G
2013-11-01
The concern addressed in the present commentary is to point out the omission of the azimuthal component Fφ of the axial acoustic radiation force provided in M. Azarpeyvand, M. A. Alibakhshi, R. Self, "Effects of multi-scattering on the performance of a single-beam acoustic manipulation device," IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 59, no. 8, pp. 1741-1749, 2012, which may suggest a miscalculation of the radiation force function Ym and its related numerical computations.
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Experimental demonstration of a single-spike hard-X-ray free-electron laser starting from noise
DOE Office of Scientific and Technical Information (OSTI.GOV)
Marinelli, A.; MacArthur, J.; Emma, P.
In this letter, we report the experimental demonstration of single-spike hard-X-ray free-electron laser pulses starting from noise with multi-eV bandwidth. Here, this is accomplished by shaping a low-charge electron beam with a slotted emittance spoiler and by adjusting the transport optics to optimize the beam-shaping accuracy. Based on elementary free-electron laser scaling laws, we estimate the pulse duration to be less than 1 fs full-width at half-maximum.
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Mechanistic Insights into Human Brain Impact Dynamics through Modal Analysis
NASA Astrophysics Data System (ADS)
Laksari, Kaveh; Kurt, Mehmet; Babaee, Hessam; Kleiven, Svein; Camarillo, David
2018-03-01
Although concussion is one of the greatest health challenges today, our physical understanding of the cause of injury is limited. In this Letter, we simulated football head impacts in a finite element model and extracted the most dominant modal behavior of the brain's deformation. We showed that the brain's deformation is most sensitive in low frequency regimes close to 30 Hz, and discovered that for most subconcussive head impacts, the dynamics of brain deformation is dominated by a single global mode. In this Letter, we show the existence of localized modes and multimodal behavior in the brain as a hyperviscoelastic medium. This dynamical phenomenon leads to strain concentration patterns, particularly in deep brain regions, which is consistent with reported concussion pathology.
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Schlernitzauer, M; Bierhals, A J; Geary, M D; Prigerson, H G; Stack, J A; Miller, M D; Pasternak, R E; Reynolds, C F
1998-01-01
The authors compared various strategies for recruiting elderly subjects with bereavement-related depression into a randomized clinical trial. Over 5 years, they empaneled 65 patients from a total of 441 subjects screened (14.7%). Response to media advertisements was the single most effective strategy (54% of subjects). Another effective, but labor-intensive, strategy was using letters to bereaved spouses found through newspaper obituaries (14%); another 14% were referred by friends who had seen study advertisements. Information letters to healthcare providers yielded no study participants. Pathways to study participation did not differ as a function of race or gender and did not influence study retention or remission rates. Our experience suggests that successful intake depends on a personal mode of recruitment.
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Waldorff, Frans Boch; Siersma, Volkert; Nielsen, Bente; Steenstrup, Annette Plesner; Bro, Flemming
2009-12-01
The aim of the present study was to evaluate whether three reminder letters mailed to GPs after dissemination of a Dementia Guideline increased the GPs' use of the corresponding e-learning programme (ELP). Single-blinded randomized trial among all GPs in Copenhagen Municipality from 1 November 2006 to 1 May 2007. A total of 15 of 320 GPs (4.7%) had a web-based logon during the study period. The intervention group had a significantly increased frequency of web-based logons (P = 0.0192) equivalent to a hazard ratio of 8.0 (95% CI: 1.03-66.1; P = 0.047). NNT was calculated to 22.2. We could not detect any significant differences in any of the secondary outcomes. Three reminder letters added to a nation-wide dissemination increased the probability for a GP logon in the ELP by a Factor 8. However, in total, only a small proportion used the ELP. Thus, further research is needed in order to consider future implementation strategies for Internet-based Continuous Medical Education activities among not primed GPs.
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Congress Seeks Tales of Piracy
ERIC Educational Resources Information Center
Read, Brock
2007-01-01
This month, leaders of two committees in the U.S. House of Representatives sent letters warning of an epidemic of online music and movie piracy to 19 colleges, singling out those schools that, in the eyes of entertainment-industry officials, have been unable to stop students from illegally downloading music and movies. Enclosed with each message…
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50 CFR Appendix E to Part 404 - Content and Syntax for Papaha
Code of Federal Regulations, 2011 CFR
2011-10-01
... field text CORAL SHIPREP // A Ship Vessel name/call sign/flag/IMO number/Federal documentation or State..., suffixed with the letter N (indicating north), followed by a single /, and a five-digit group giving... of persons on board // W/15// Table E.1 Notes *Categories of hazardous cargoes means goods classified...
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Single Molecule Detection Using a Silicon Nanopore-Nanotransistor Integrated Circuit
2006-01-01
indicates the dipole moment of the DNA bases projected along the pore axis. During this simulation 14 bases translocated through the pore. The letters...recorded S tU signals are plotted versus time on the top figure. The bottom figure indicates C" the dipole moment of DNA bases 0 - projected along the
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-30
... facilities; (2) supplier relationships; (3) management; and (4) customer base.\\6\\ \\6\\ See Letter from Hebei...; and (4) customer base.\\8\\ Although no single factor will necessarily provide a dispositive indication... management, suppliers, customer base, and production facilities that the Department considers in its...
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9 CFR 108.4 - Preparation of blueprints.
Code of Federal Regulations, 2014 CFR
2014-01-01
... regular blueprint paper or a good grade of white paper of any one of the American standard trimmed sizes... blueprint is revised. Indicate the scale used. (b) Use a single sheet of paper for each floor of all... floor. (e) Identify all rooms by letters or numbers. (f) Show the location of important stationary...
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9 CFR 108.4 - Preparation of blueprints.
Code of Federal Regulations, 2011 CFR
2011-01-01
... regular blueprint paper or a good grade of white paper of any one of the American standard trimmed sizes... blueprint is revised. Indicate the scale used. (b) Use a single sheet of paper for each floor of all... floor. (e) Identify all rooms by letters or numbers. (f) Show the location of important stationary...
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Components of Attention Modulated by Temporal Expectation
ERIC Educational Resources Information Center
Sørensen, Thomas Alrik; Vangkilde, Signe; Bundesen, Claus
2015-01-01
By varying the probabilities that a stimulus would appear at particular times after the presentation of a cue and modeling the data by the theory of visual attention (Bundesen, 1990), Vangkilde, Coull, and Bundesen (2012) provided evidence that the speed of encoding a singly presented stimulus letter into visual short-term memory (VSTM) is…
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Rising, Kindle; Rapcsak, Steven Z.; Beeson, Pélagie M.
2015-01-01
Purpose Damage to left ventral occipito-temporal cortex can give rise to written language impairment characterized by pure alexia/letter-by-letter (LBL) reading, as well as surface alexia and agraphia. The purpose of this study was to examine the therapeutic effects of a combined treatment approach to address concurrent LBL reading with surface alexia/agraphia. Method Simultaneous treatment to address slow reading and errorful spelling was administered to 3 individuals with reading and spelling impairments after left ventral occipito-temporal damage due to posterior cerebral artery stroke. Single-word reading/spelling accuracy, reading latencies, and text reading were monitored as outcome measures for the combined effects of multiple oral re-reading treatment and interactive spelling treatment. Results After treatment, participants demonstrated faster and more accurate single-word reading and improved text-reading rates. Spelling accuracy also improved, particularly for untrained irregular words, demonstrating generalization of the trained interactive spelling strategy. Conclusion This case series characterizes concomitant LBL with surface alexia/agraphia and demonstrates a successful treatment approach to address both the reading and spelling impairment. PMID:26110814
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Kim, Esther S; Rising, Kindle; Rapcsak, Steven Z; Beeson, Pélagie M
2015-10-01
Damage to left ventral occipito-temporal cortex can give rise to written language impairment characterized by pure alexia/letter-by-letter (LBL) reading, as well as surface alexia and agraphia. The purpose of this study was to examine the therapeutic effects of a combined treatment approach to address concurrent LBL reading with surface alexia/agraphia. Simultaneous treatment to address slow reading and errorful spelling was administered to 3 individuals with reading and spelling impairments after left ventral occipito-temporal damage due to posterior cerebral artery stroke. Single-word reading/spelling accuracy, reading latencies, and text reading were monitored as outcome measures for the combined effects of multiple oral re-reading treatment and interactive spelling treatment. After treatment, participants demonstrated faster and more accurate single-word reading and improved text-reading rates. Spelling accuracy also improved, particularly for untrained irregular words, demonstrating generalization of the trained interactive spelling strategy. This case series characterizes concomitant LBL with surface alexia/agraphia and demonstrates a successful treatment approach to address both the reading and spelling impairment.
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Barnhardt, Terrence M
2005-10-01
Three experiments explored the distinction between identification and production processes (e.g., Gabrieli et al., 1999). A stem decision test was introduced, in which participants were asked to state whether there were any English words that began with the presented three-letter stems. In Experiment 1, stem decision priming was robust for single-solution stems, but much reduced for many-solution stems. In Experiment 2, the solutions effect in stem decision was replicated in a within-subjects design, as was the contrast between the presence of priming in a many-solution stem completion test and the absence of priming in a many-solution stem decision test. In Experiment 3, for each critical many-solution stem in the stem decision test, participants studied three words that began with those three letters. Again, priming was not observed. These results were consistent with the notions that (a) many-solution stem completion relies on production processes, (b) the stem decision test eliminates production processes, and (c) single-solution priming relies on identification processes, regardless of whether the test is stem completion or stem decision.
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Flexible radio-frequency single-crystal germanium switch on plastic substrates
NASA Astrophysics Data System (ADS)
Qin, Guoxuan; Cai, Tianhao; Yuan, Hao-Chih; Seo, Jung-Hun; Ma, Jianguo; Ma, Zhenqiang
2014-04-01
This Letter presents the realization and characterizations of the flexible radio-frequency (RF)/microwave switches on plastic substrates employing single-crystal germanium (Ge) nanomembranes. The fabricated flexible Ge single-pole, single-throw (SPST) switches display high frequency responses (e.g., insertion loss of <1.3 dB at up to 30 GHz and isolation >10 dB at up to ˜13 GHz). RF performance tradeoff exists for the flexible Ge switches and the major affecting parameters are determined. The flexible Ge SPST switch shows better RF property to that of the flexible Si SPST switch. Underlying mechanism is investigated by theoretical analysis and modeling of switches with different structures.
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I Karipidis, Iliana; Pleisch, Georgette; Röthlisberger, Martina; Hofstetter, Christoph; Dornbierer, Dario; Stämpfli, Philipp; Brem, Silvia
2017-02-01
Learning letter-speech sound correspondences is a major step in reading acquisition and is severely impaired in children with dyslexia. Up to now, it remains largely unknown how quickly neural networks adopt specific functions during audiovisual integration of linguistic information when prereading children learn letter-speech sound correspondences. Here, we simulated the process of learning letter-speech sound correspondences in 20 prereading children (6.13-7.17 years) at varying risk for dyslexia by training artificial letter-speech sound correspondences within a single experimental session. Subsequently, we acquired simultaneously event-related potentials (ERP) and functional magnetic resonance imaging (fMRI) scans during implicit audiovisual presentation of trained and untrained pairs. Audiovisual integration of trained pairs correlated with individual learning rates in right superior temporal, left inferior temporal, and bilateral parietal areas and with phonological awareness in left temporal areas. In correspondence, a differential left-lateralized parietooccipitotemporal ERP at 400 ms for trained pairs correlated with learning achievement and familial risk. Finally, a late (650 ms) posterior negativity indicating audiovisual congruency of trained pairs was associated with increased fMRI activation in the left occipital cortex. Taken together, a short (<30 min) letter-speech sound training initializes audiovisual integration in neural systems that are responsible for processing linguistic information in proficient readers. To conclude, the ability to learn grapheme-phoneme correspondences, the familial history of reading disability, and phonological awareness of prereading children account for the degree of audiovisual integration in a distributed brain network. Such findings on emerging linguistic audiovisual integration could allow for distinguishing between children with typical and atypical reading development. Hum Brain Mapp 38:1038-1055, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
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Rothenbuehler, Simon P; Waeber, David; Brinkmann, Christian K; Wolf, Sebastian; Wolf-Schnurrbusch, Ute E K
2009-05-01
To demonstrate not only prevention of vision loss but also improvement in best-corrected visual acuity (BCVA) after treatment with ranibizumab on a variable-dosing regimen over 24 months in patients with age-related macular degeneration (AMD). Interventional case series. Institutional. One hundred and thirty-eight eyes of 138 patients treated intravitreally with 0.5 mg ranibizumab (Lucentis; Novartis, Basel, Switzerland). Age above 50 years, BCVA 0.2 to 1.2 logarithm of the minimal angle of resolution (logMAR), primary or recurrent subfoveal choroidal neovascularization (CNV) secondary to AMD. After single initial treatment, monthly follow-up examination. Retreatment in case of one of the following: sign of subretinal fluid or intraretinal edema, increase in central retinal thickness (CRT) on optical coherence tomography (OCT), active CNV on fluorescein angiography, increase of metamorphopsia, and loss of BCVA > 5 letters on Early Treatment Diabetic Retinopathy Study (ETDRS) chart. Compared with baseline: proportion of eyes gaining > or = 15 letters, proportion of eyes losing or gaining < 15 letters, change in CRT. After 24 months, 30% of eyes gained > or = 15 letters. After 24 months, 55% of eyes lost or gained < 15 letters. Mean CRT of 386 +/- 145 microm at baseline was significantly reduced to 211 +/- 39 microm after 24 months (P = .036). Mean injection number per patient was 5.6 +/- 2.9 and 4.3 +/- 3.8 from baseline to month 12 and month 12 to 24, respectively. Intravitreal ranibizumab on a variable-dosing regimen was effective in significantly increasing mean BVCA and reducing CRT. This beneficial outcome was achieved with a low-rate of mild ocular adverse effects among our patients.
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Precursors of Reading Difficulties in Czech and Slovak Children At-Risk of Dyslexia.
Moll, Kristina; Thompson, Paul A; Mikulajova, Marina; Jagercikova, Zuzana; Kucharska, Anna; Franke, Helena; Hulme, Charles; Snowling, Margaret J
2016-05-01
Children with preschool language difficulties are at high risk of literacy problems; however, the nature of the relationship between delayed language development and dyslexia is not understood. Three hundred eight Slovak and Czech children were recruited into three groups: family risk of dyslexia, speech/language difficulties and controls, and were assessed three times from kindergarten until Grade 1. There was a twofold increase in probability of reading problems in each risk group. Precursors of 'dyslexia' included difficulties in oral language and code-related skills (phoneme awareness, letter-knowledge and rapid automatized naming); poor performance in phonological memory and vocabulary was observed in both affected and unaffected high-risk peers. A two-group latent variable path model shows that early language skills predict code-related skills, which in turn predict literacy skills. Findings suggest that dyslexia in Slavic languages has its origins in early language deficits, and children who succumb to reading problems show impaired code-related skills before the onset of formal reading instruction. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.
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Information trade-offs for optical quantum communication.
Wilde, Mark M; Hayden, Patrick; Guha, Saikat
2012-04-06
Recent work has precisely characterized the achievable trade-offs between three key information processing tasks-classical communication (generation or consumption), quantum communication (generation or consumption), and shared entanglement (distribution or consumption), measured in bits, qubits, and ebits per channel use, respectively. Slices and corner points of this three-dimensional region reduce to well-known protocols for quantum channels. A trade-off coding technique can attain any point in the region and can outperform time sharing between the best-known protocols for accomplishing each information processing task by itself. Previously, the benefits of trade-off coding that had been found were too small to be of practical value (viz., for the dephasing and the universal cloning machine channels). In this Letter, we demonstrate that the associated performance gains are in fact remarkably high for several physically relevant bosonic channels that model free-space or fiber-optic links, thermal-noise channels, and amplifiers. We show that significant performance gains from trade-off coding also apply when trading photon-number resources between transmitting public and private classical information simultaneously over secret-key-assisted bosonic channels. © 2012 American Physical Society
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Learning to Write Letters: Examination of Student and Letter Factors
Puranik, Cynthia S.; Petscher, Yaacov; Lonigan, Christopher J.
2016-01-01
Learning to write the letters of the alphabet is an important part of learning how to write conventionally. In this study, we investigated critical factors in the development of letter-writing skills using exploratory item response models to simultaneously account for variance in responses due to differences between students and between letters. Letter-writing skills were assessed in 415 preschool children aged 3 to 5 years. At the student level, we examined the contribution of letter-name knowledge, letter-sound knowledge, and phonological awareness to letter-writing skills. At the letter level, we examined seven intrinsic and extrinsic factors in understanding how preschool children learn to write alphabet letters: first letter of name, letters in name, letter order, textual frequency, number of strokes, symmetry, and letter type. Results indicated that variation in letter-writing skills was accounted for more by differences between students rather than by differences between letters, with most of the variability accounted for by letter-name knowledge and age. Although significant, the contribution of letter-sound knowledge and phonological awareness was relatively small. Student-level mechanisms underlying the acquisition of letter-writing skills are similar to the mechanisms underlying the learning of letter sounds. However, letter characteristics, which appear to play a major role in the learning of letter names and letter sounds, did not appear to influence learning how to write letters in a substantial way. The exception was if the letter was in the child’s name. PMID:25181463
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Mitochondrial Genomes of Kinorhyncha: trnM Duplication and New Gene Orders within Animals.
Popova, Olga V; Mikhailov, Kirill V; Nikitin, Mikhail A; Logacheva, Maria D; Penin, Aleksey A; Muntyan, Maria S; Kedrova, Olga S; Petrov, Nikolai B; Panchin, Yuri V; Aleoshin, Vladimir V
2016-01-01
Many features of mitochondrial genomes of animals, such as patterns of gene arrangement, nucleotide content and substitution rate variation are extensively used in evolutionary and phylogenetic studies. Nearly 6,000 mitochondrial genomes of animals have already been sequenced, covering the majority of animal phyla. One of the groups that escaped mitogenome sequencing is phylum Kinorhyncha-an isolated taxon of microscopic worm-like ecdysozoans. The kinorhynchs are thought to be one of the early-branching lineages of Ecdysozoa, and their mitochondrial genomes may be important for resolving evolutionary relations between major animal taxa. Here we present the results of sequencing and analysis of mitochondrial genomes from two members of Kinorhyncha, Echinoderes svetlanae (Cyclorhagida) and Pycnophyes kielensis (Allomalorhagida). Their mitochondrial genomes are circular molecules approximately 15 Kbp in size. The kinorhynch mitochondrial gene sequences are highly divergent, which precludes accurate phylogenetic inference. The mitogenomes of both species encode a typical metazoan complement of 37 genes, which are all positioned on the major strand, but the gene order is distinct and unique among Ecdysozoa or animals as a whole. We predict four types of start codons for protein-coding genes in E. svetlanae and five in P. kielensis with a consensus DTD in single letter code. The mitochondrial genomes of E. svetlanae and P. kielensis encode duplicated methionine tRNA genes that display compensatory nucleotide substitutions. Two distant species of Kinorhyncha demonstrate similar patterns of gene arrangements in their mitogenomes. Both genomes have duplicated methionine tRNA genes; the duplication predates the divergence of two species. The kinorhynchs share a few features pertaining to gene order that align them with Priapulida. Gene order analysis reveals that gene arrangement specific of Priapulida may be ancestral for Scalidophora, Ecdysozoa, and even Protostomia.
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Mitochondrial Genomes of Kinorhyncha: trnM Duplication and New Gene Orders within Animals
Popova, Olga V.; Mikhailov, Kirill V.; Nikitin, Mikhail A.; Logacheva, Maria D.; Penin, Aleksey A.; Muntyan, Maria S.; Kedrova, Olga S.; Petrov, Nikolai B.; Panchin, Yuri V.
2016-01-01
Many features of mitochondrial genomes of animals, such as patterns of gene arrangement, nucleotide content and substitution rate variation are extensively used in evolutionary and phylogenetic studies. Nearly 6,000 mitochondrial genomes of animals have already been sequenced, covering the majority of animal phyla. One of the groups that escaped mitogenome sequencing is phylum Kinorhyncha—an isolated taxon of microscopic worm-like ecdysozoans. The kinorhynchs are thought to be one of the early-branching lineages of Ecdysozoa, and their mitochondrial genomes may be important for resolving evolutionary relations between major animal taxa. Here we present the results of sequencing and analysis of mitochondrial genomes from two members of Kinorhyncha, Echinoderes svetlanae (Cyclorhagida) and Pycnophyes kielensis (Allomalorhagida). Their mitochondrial genomes are circular molecules approximately 15 Kbp in size. The kinorhynch mitochondrial gene sequences are highly divergent, which precludes accurate phylogenetic inference. The mitogenomes of both species encode a typical metazoan complement of 37 genes, which are all positioned on the major strand, but the gene order is distinct and unique among Ecdysozoa or animals as a whole. We predict four types of start codons for protein-coding genes in E. svetlanae and five in P. kielensis with a consensus DTD in single letter code. The mitochondrial genomes of E. svetlanae and P. kielensis encode duplicated methionine tRNA genes that display compensatory nucleotide substitutions. Two distant species of Kinorhyncha demonstrate similar patterns of gene arrangements in their mitogenomes. Both genomes have duplicated methionine tRNA genes; the duplication predates the divergence of two species. The kinorhynchs share a few features pertaining to gene order that align them with Priapulida. Gene order analysis reveals that gene arrangement specific of Priapulida may be ancestral for Scalidophora, Ecdysozoa, and even Protostomia. PMID:27755612
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Quality of head injury coding from autopsy reports with AIS © 2005 update 2008.
Schick, Sylvia; Humrich, Anton; Graw, Matthias
2018-02-28
ABSTACT Objective: Coding injuries from autopsy reports of traffic accident victims according to Abbreviated Injury Scale AIS © 2005 update 2008 [1] is quite time consuming. The suspicion arose, that many issues leading to discussion between coder and control reader were based on information required by the AIS that was not documented in the autopsy reports. To quantify this suspicion, we introduced an AIS-detail-indicator (AIS-DI). To each injury in the AIS Codebook one letter from A to N was assigned indicating the level of detail. Rules were formulated to receive repeatable assignments. This scheme was applied to a selection of 149 multiply injured traffic fatalities. The frequencies of "not A" codes were calculated for each body region and it was analysed, why the most detailed level A had not been coded. As a first finding, the results of the head region are presented. 747 AIS head injury codes were found in 137 traffic fatalities, and 60% of these injuries were coded with an AIS-DI of level A. There are three different explanations for codes of AIS-DI "not A": Group 1 "Missing information in autopsy report" (5%), Group 2 "Clinical data required by AIS" (20%), and Group 3 "AIS system determined" (15%). Groups 1 and 2 show consequences for the ISS in 25 cases. Other body regions might perform differently. The AIS-DI can indicate the quality of the underlying data basis and, depending on the aims of different AIS users it can be a helpful tool for quality checks.
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Low-dose caffeine discrimination and self-reported mood effects in normal volunteers.
Silverman, K; Griffiths, R R
1992-01-01
A caffeine versus placebo discrimination procedure was used to determine the lowest caffeine dose that could produce discrimination and self-reported mood effects in normal volunteers. During daily sessions under double-blind conditions, caffeine-abstinent subjects orally ingested a capsule containing 178 mg caffeine or placebo. Before beginning discrimination training, the compounds were identified to subjects by letter codes. Fifteen, 30, and 45 min after capsule ingestion, subjects guessed the capsule's letter code. Correct guesses at 45 min earned money. After each session, subjects received a supplementary capsule containing caffeine or placebo to ensure that, within each phase of the study, subjects received the same daily dose of caffeine equal to the training dose. Five of the 15 subjects acquired the caffeine versus placebo discrimination within the first 20 sessions (greater than or equal to 75% correct); 6 other subjects acquired the discrimination with additional training. Nine subjects who acquired the discrimination were subsequently trained at progressively lower caffeine doses. In general, the lowest dose to produce discrimination (greater than or equal to 75% correct) was also the lowest dose to produce self-reported mood effects: 4 subjects showed discrimination and self-reported mood effects at 100 mg caffeine, 2 at 56 mg, 1 at 32 mg, and 1 at 18 mg. One of these subjects also showed self-reported mood effects at 10 mg. The present study documents discriminative stimulus and self-reported mood effects of caffeine at doses below those previously shown to affect any behavior in normal volunteers. PMID:1548451
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Electrophysiological evidence for differential processing of numerical quantity and order in humans.
Turconi, Eva; Jemel, Boutheina; Rossion, Bruno; Seron, Xavier
2004-09-01
It is yet unclear whether the processing of number magnitude and order rely on common or different functional processes and neural substrates. On the one hand, recent neuroimaging studies show that quantity and order coding activate the same areas in the parietal and prefrontal cortices. On the other hand, evidence from developmental and neuropsychological studies suggest dissociated mechanisms for processing quantity and order information. To clarify this issue, the present study investigated the spatio-temporal course of quantity and order coding operations using event-related potentials (ERPs). Twenty-four subjects performed a quantity task (classifying numbers as smaller or larger than 15) and an order task on the same material (classifying numbers as coming before or after 15), as well as a control order task on letters (classifying letters as coming before or after M). Behavioral results showed a classical distance effect (decreasing reaction times [RTs] with increasing distance from the standard) for all tasks. In agreement with previous electrophysiological evidence, this effect was significant on a P2 parietal component for numerical material. However, the difference between processing numbers close or far from the target appeared earlier and was larger on the left hemisphere for quantity processing, while it was delayed and bilateral for order processing. There was also a significant distance effect in all tasks on parietal sites for the following P3 component elicited by numbers, but this effect was larger on prefrontal areas for the order judgment. In conclusion, both quantity and order show similar behavioral effects, but they are associated with different spatio-temporal courses in parietal and prefrontal cortices.
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Solís, D; Jiménez-Barbero, J; Kaltner, H; Romero, A; Siebert, H C; von der Lieth, C W; Gabius, H J
2001-01-01
The term 'code' in biological information transfer appears to be tightly and hitherto exclusively connected with the genetic code based on nucleotides and translated into functional activities via proteins. However, the recent appreciation of the enormous coding capacity of oligosaccharide chains of natural glycoconjugates has spurred to give heed to a new concept: versatile glycan assembly by the genetically encoded glycosyltransferases endows cells with a probably not yet fully catalogued array of meaningful messages. Enciphered by sugar receptors such as endogenous lectins the information of code words established by a series of covalently linked monosaccharides as letters for example guides correct intra- and intercellular routing of glycoproteins, modulates cell proliferation or migration and mediates cell adhesion. Evidently, the elucidation of the structural frameworks and the recognition strategies within the operation of the sugar code poses a fascinating conundrum. The far-reaching impact of this recognition mode on the level of cells, tissues and organs has fueled vigorous investigations to probe the subtleties of protein-carbohydrate interactions. This review presents information on the necessarily concerted approach using X-ray crystallography, molecular modeling, nuclear magnetic resonance spectroscopy, thermodynamic analysis and engineered ligands and receptors. This part of the treatise is flanked by exemplarily chosen insights made possible by these techniques. Copyright 2001 S. Karger AG, Basel
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The Effects of Test Trial and Processing Level on Immediate and Delayed Retention.
Chang, Sau Hou
2017-03-01
The purpose of the present study was to investigate the effects of test trial and processing level on immediate and delayed retention. A 2 × 2 × 2 mixed ANOVAs was used with two between-subject factors of test trial (single test, repeated test) and processing level (shallow, deep), and one within-subject factor of final recall (immediate, delayed). Seventy-six college students were randomly assigned first to the single test (studied the stimulus words three times and took one free-recall test) and the repeated test trials (studied the stimulus words once and took three consecutive free-recall tests), and then to the shallow processing level (asked whether each stimulus word was presented in capital letter or in small letter) and the deep processing level (whether each stimulus word belonged to a particular category) to study forty stimulus words. The immediate test was administered five minutes after the trials, whereas the delayed test was administered one week later. Results showed that single test trial recalled more words than repeated test trial in immediate final free-recall test, participants in deep processing performed better than those in shallow processing in both immediate and delayed retention. However, the dominance of single test trial and deep processing did not happen in delayed retention. Additional study trials did not further enhance the delayed retention of words encoded in deep processing, but did enhance the delayed retention of words encoded in shallow processing.
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The Effects of Test Trial and Processing Level on Immediate and Delayed Retention
Chang, Sau Hou
2017-01-01
The purpose of the present study was to investigate the effects of test trial and processing level on immediate and delayed retention. A 2 × 2 × 2 mixed ANOVAs was used with two between-subject factors of test trial (single test, repeated test) and processing level (shallow, deep), and one within-subject factor of final recall (immediate, delayed). Seventy-six college students were randomly assigned first to the single test (studied the stimulus words three times and took one free-recall test) and the repeated test trials (studied the stimulus words once and took three consecutive free-recall tests), and then to the shallow processing level (asked whether each stimulus word was presented in capital letter or in small letter) and the deep processing level (whether each stimulus word belonged to a particular category) to study forty stimulus words. The immediate test was administered five minutes after the trials, whereas the delayed test was administered one week later. Results showed that single test trial recalled more words than repeated test trial in immediate final free-recall test, participants in deep processing performed better than those in shallow processing in both immediate and delayed retention. However, the dominance of single test trial and deep processing did not happen in delayed retention. Additional study trials did not further enhance the delayed retention of words encoded in deep processing, but did enhance the delayed retention of words encoded in shallow processing. PMID:28344679
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Adams, Sarah C.; Kiefer, Markus
2012-01-01
Recent studies challenged the classical notion of automaticity and indicated that even unconscious automatic semantic processing is under attentional control to some extent. In line with our attentional sensitization model, these data suggest that a sensitization of semantic pathways by a semantic task set is necessary for subliminal semantic priming to occur while non-semantic task sets attenuate priming. In the present study, we tested whether masked semantic priming is also reduced by phonological task sets using the previously developed induction task paradigm. This would substantiate the notion that attention to semantics is necessary for eliciting unconscious semantic priming. Participants first performed semantic and phonological induction tasks that should either activate a semantic or a phonological task set. Subsequent to the induction task, a masked prime word, either associated or non-associated with the following lexical decision target word, was presented. Across two experiments, we varied the nature of the phonological induction task (word phonology vs. letter phonology) to assess whether the attentional focus on the entire word vs. single letters modulates subsequent masked semantic priming. In both experiments, subliminal semantic priming was only found subsequent to the semantic induction task, but was attenuated following either phonological induction task. These results indicate that attention to phonology attenuates subsequent semantic processing of unconsciously presented primes whether or not attention is directed to the entire word or to single letters. The present findings therefore substantiate earlier evidence that an attentional orientation toward semantics is necessary for subliminal semantic priming to be elicited. PMID:22952461
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VizieR Online Data Catalog: Blazars in the Swift-BAT hard X-ray sky (Maselli+, 2010)
NASA Astrophysics Data System (ADS)
Maselli, A.; Cusumano, G.; Massaro, E.; La Parola, V.; Segreto, A.; Sbarufatti, B.
2010-06-01
We reported the list of hard X-ray blazars obtained adopting sigma=3 as detection threshold: with this choice a number of three spurious sources over a total of 121 blazars is expected. Each blazar is identified by a three-letter code, where the first two are BZ for blazar and the third one specifies the type, followed by the truncated equatorial coordinates (J2000). The codes are defined in the "Note (1)" below. We obtained 69 FSRQs, 24 BL Lac objects and 28 blazars of uncertain classification, representing 4.4%, 2.4% and 11.0% of the corresponding populations classified in the BZCAT, respectively. This sample has been compared with other lists and catalogues found in literature (Tueller et al., 2010, Cat. J/ApJS/186/378, Ajello et al. 2009ApJ...699..603A, Cusumano et al., 2010, Cat. J/A+A/510/A48). (1 data file).
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Schurz, Matthias; Sturm, Denise; Richlan, Fabio; Kronbichler, Martin; Ladurner, Gunther; Wimmer, Heinz
2010-01-01
Based on our previous work, we expected the Visual Word Form Area (VWFA) in the left ventral visual pathway to be engaged by both whole-word recognition and by serial sublexical coding of letter strings. To examine this double function, a phonological lexical decision task (i.e., “Does xxx sound like an existing word?”) presented short and long letter strings of words, pseudohomophones, and pseudowords (e.g., Taxi, Taksi and Tazi). Main findings were that the length effect for words was limited to occipital regions and absent in the VWFA. In contrast, a marked length effect for pseudowords was found throughout the ventral visual pathway including the VWFA, as well as in regions presumably engaged by visual attention and silent-articulatory processes. The length by lexicality interaction on brain activation corresponds to well-established behavioral findings of a length by lexicality interaction on naming latencies and speaks for the engagement of the VWFA by both lexical and sublexical processes. PMID:19896538
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Schurz, Matthias; Sturm, Denise; Richlan, Fabio; Kronbichler, Martin; Ladurner, Gunther; Wimmer, Heinz
2010-02-01
Based on our previous work, we expected the Visual Word Form Area (VWFA) in the left ventral visual pathway to be engaged by both whole-word recognition and by serial sublexical coding of letter strings. To examine this double function, a phonological lexical decision task (i.e., "Does xxx sound like an existing word?") presented short and long letter strings of words, pseudohomophones, and pseudowords (e.g., Taxi, Taksi and Tazi). Main findings were that the length effect for words was limited to occipital regions and absent in the VWFA. In contrast, a marked length effect for pseudowords was found throughout the ventral visual pathway including the VWFA, as well as in regions presumably engaged by visual attention and silent-articulatory processes. The length by lexicality interaction on brain activation corresponds to well-established behavioral findings of a length by lexicality interaction on naming latencies and speaks for the engagement of the VWFA by both lexical and sublexical processes. Copyright (c) 2009 Elsevier Inc. All rights reserved.
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The optimal duration of frequency-volume charts related to compliance and reliability.
van Haarst, Ernst P; Bosch, J L H Ruud
2014-03-01
To assess Frequency-volume charts (FVCs) for the yield of additional recorded days and the ideal duration of recording related to compliance and reliability. Of 500 consecutive urologic outpatients willing to complete a 7-day FVC, 378 FVCs were evaluable. During seven consecutive days every voiding time and volume were recorded. Missed entries were indicated with a coded letter, thereby assessing the true frequency and compliance. Reliability is the agreement of the day-to-day FVC parameters with the 7-day FVC pattern. Single-day reliability was assessed and used in the Spearman-Brown formula. FVCs of 228 male and 150 females were evaluated. Mean age was 55.2 years (standard deviation [SD]: 16.2 years), and mean 24-hr urine production was 1,856 ml (SD: 828 ml). The percentage of patients with complete FVCs decreased from 78% on day 2 to 58% on day 7, and dropped below 70% after 4 days. Single-day reliability was r = 0.63 for nocturnal urine production, r = 0.72 for 24-hr urine production, and r = 0.80 for mean voided volume. At 5 days, reliability of 90% was achieved for all parameters. With each additional day, FVCs showed a decrease in compliance and an increase in reliability. At day 3, reliability of 80% was achieved for all FVC parameters, but compliance dropped to 73%. Beyond 5 days, the yield of additional recorded days was limited. We advocate an FVC duration of 3 days, but the duration may be shortened or extended depending on the goal of the FVC. © 2013 Wiley Periodicals, Inc.
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Pitchiaya, Sethuramasundaram; Krishnan, Vishalakshi; Custer, Thomas C.; Walter, Nils G.
2013-01-01
Non-coding RNAs (ncRNAs) recently were discovered to outnumber their protein-coding counterparts, yet their diverse functions are still poorly understood. Here we report on a method for the intracellular Single-molecule High Resolution Localization and Counting (iSHiRLoC) of microRNAs (miRNAs), a conserved, ubiquitous class of regulatory ncRNAs that controls the expression of over 60% of all mammalian protein coding genes post-transcriptionally, by a mechanism shrouded by seemingly contradictory observations. We present protocols to execute single particle tracking (SPT) and single-molecule counting of functional microinjected, fluorophore-labeled miRNAs and thereby extract diffusion coefficients and molecular stoichiometries of micro-ribonucleoprotein (miRNP) complexes from living and fixed cells, respectively. This probing of miRNAs at the single molecule level sheds new light on the intracellular assembly/disassembly of miRNPs, thus beginning to unravel the dynamic nature of this important gene regulatory pathway and facilitating the development of a parsimonious model for their obscured mechanism of action. PMID:23820309
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Yang, Qi; Al Amin, Abdullah; Chen, Xi; Ma, Yiran; Chen, Simin; Shieh, William
2010-08-02
High-order modulation formats and advanced error correcting codes (ECC) are two promising techniques for improving the performance of ultrahigh-speed optical transport networks. In this paper, we present record receiver sensitivity for 107 Gb/s CO-OFDM transmission via constellation expansion to 16-QAM and rate-1/2 LDPC coding. We also show the single-channel transmission of a 428-Gb/s CO-OFDM signal over 960-km standard-single-mode-fiber (SSMF) without Raman amplification.
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Kim, Sang Hyun
2013-09-01
The purpose of this study was to investigate applicants' behavioral characteristics based on the evaluation of cognitive, affective and social domain shown in self introduction letter and professor's recommendation letter. Self introduction letters and professor's recommendation letters of 109 applicants students who applied to medical school were collected. Frequency analysis and simple correlation were done in self introduction letter and professor's recommendation letter. Frequency analysis showed affective characteristics were most often mentioned in self introduction letter, and cognitive characteristics were most frequently described in professor's recommendation letter. There was a strong correlation between cognitive domains of self introduction letter and cognitive domain of professor's recommendation letter. There was a strong correlation between affective domain of self introduction letter and cognitive domain professor's recommendation letter. It is very important to make full use of self introduction letter and professor's recommendation letter for selecting medical students. Through the frequency analysis and simple correlation, more specific guidelines need to be suggested in order to secure fairness and objectivity in the evaluation of self-introduction letter and professor's recommendation letter.
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Simultaneous Semi-Distributed Model Calibration Guided by ...
Modelling approaches to transfer hydrologically-relevant information from locations with streamflow measurements to locations without such measurements continues to be an active field of research for hydrologists. The Pacific Northwest Hydrologic Landscapes (PNW HL) provide a solid conceptual classification framework based on our understanding of dominant processes. A Hydrologic Landscape code (5 letter descriptor based on physical and climatic properties) describes each assessment unit area, and these units average area 60km2. The core function of these HL codes is to relate and transfer hydrologically meaningful information between watersheds without the need for streamflow time series. We present a novel approach based on the HL framework to answer the question “How can we calibrate models across separate watersheds simultaneously, guided by our understanding of dominant processes?“. We should be able to apply the same parameterizations to assessment units of common HL codes if 1) the Hydrologic Landscapes contain hydrologic information transferable between watersheds at a sub-watershed-scale and 2) we use a conceptual hydrologic model and parameters that reflect the hydrologic behavior of a watershed. In this study, This work specifically tests the ability or inability to use HL-codes to inform and share model parameters across watersheds in the Pacific Northwest. EPA’s Western Ecology Division has published and is refining a framework for defining la
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[Potentially addictive drugs on reimbursable prescription for chronic severe pain].
Persheim, Marthe Sæther; Helland, Arne; Spigset, Olav; Slørdal, Lars
2013-01-22
Changes in the Norwegian drug reimbursement system in 2008 included the establishment of a new reimbursement code (-71) which authorises coverage of expenditures for potentially addictive drugs in patients with severe, predominantly non-malignant, chronic pain. This reform has hitherto not been evaluated. We assessed national data on drug reimbursements in accordance with code -71 for the period 2008-2011, and anonymised copies of all confirmation letters granting reimbursements according to code -71 in Central Norway (three counties) for 2010. Approximately 1300 individual applicants' gender and age, diagnosis, potentially addictive drug applied for, drug dose, and identity and specialty of the prescribing physician, were recorded. From the time of establishment, reimbursement code -71 has been utilised by an increasing number of individuals, encompassing close to 10,000 subjects in 3rd quarter 2011. Almost one-third of the approved applications were for pregabalin, and the rest were for various opioids. The diagnoses were most often derived from the musculoskeletal and nervous systems, and were often nonspecific. A considerable number of treatment regimens were not in accordance with current principles for the management of chronic non-malignant pain, and drug doses were at times remarkably high. Aspects of this drug reimbursement regulation should be closely monitored, and may be in need of changes.
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-19
..., particularly in times of market stress, and exacerbate market volatility.\\8\\ \\7\\ See BATS Letter at 2; Deutsche... Volatility Guard to work within the parameters of the recently adopted single-stock circuit breakers, and to... of individual exchange volatility moderators in times of market stress. In addition, as noted above...
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Simple Proof of Jury Test for Complex Polynomials
NASA Astrophysics Data System (ADS)
Choo, Younseok; Kim, Dongmin
Recently some attempts have been made in the literature to give simple proofs of Jury test for real polynomials. This letter presents a similar result for complex polynomials. A simple proof of Jury test for complex polynomials is provided based on the Rouché's Theorem and a single-parameter characterization of Schur stability property for complex polynomials.
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Phonological Processing Skills as Predictors of Literacy amongst Arabic Speaking Bahraini Children
ERIC Educational Resources Information Center
al Mannai, Haya; Everatt, John
2005-01-01
This paper reports a study of the reading and spelling skills of grades 1-3 Arabic-speaking children in Bahrain. Children were tested on their literacy skills (single word reading and spelling), their ability to decode letter strings (non-word reading) and measures of phonological awareness, short-term memory, speed of processing and non-verbal…
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ERIC Educational Resources Information Center
Potter, Lee Ann
2005-01-01
President Ronald Reagan nominated a woman to serve on the United States Supreme Court. He did so through a single-page form letter, completed in part by hand and in part by typewriter, announcing Sandra Day O'Connor as his nominee. While the document serves as evidence of a historic event, it is also a tangible illustration of abstract concepts…
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Neglect Dyslexia: Frequency, Association with Other Hemispatial Neglects, and Lesion Localization
ERIC Educational Resources Information Center
Lee, Byung Hwa; Suh, Mee Kyung; Kim, Eun-Joo; Seo, Sang Won; Choi, Kyung Mook; Kim, Gyeong-Moon; Chung, Chin-Sang; Heilman, Kenneth M.; Na, Duk L.
2009-01-01
Patients with right hemisphere injury often omit or misread words on the left side of a page or the beginning letters of single words (neglect dyslexia). Our study involving a large sample of acute right hemisphere stroke investigated (1) the frequency of neglect dyslexia (ND), (2) the association between ND and other types of contralesional…
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Author Correction: Single-molecule imaging by optical absorption
NASA Astrophysics Data System (ADS)
Celebrano, Michele; Kukura, Philipp; Renn, Alois; Sandoghdar, Vahid
2018-05-01
In the Supplementary Video initially published with this Letter, the right-hand panel displaying the fluorescence emission was not showing on some video players due to a formatting problem; this has now been fixed. The video has also now been amended to include colour scale bars for both the left- (differential transmission signal) and right-hand panels.
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ERIC Educational Resources Information Center
Lorenzen, Elizabeth A.; And Others
This paper describes the various types of correspondence used in the job search process and provides guidelines and samples of each type. Types of letters discussed include cover letters (including letters of application and prospecting letters), networking letters, thank-you letters, acceptance letters, withdrawal letters, and rejection of offer…
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Overcoming the effect of letter confusability in letter-by-letter reading: a rehabilitation study.
Harris, Lara; Olson, Andrew; Humphreys, Glyn
2013-01-01
Patients who read in a letter-by-letter manner can demonstrate effects of lexical variables when reading words comprised of low confusability letters, suggesting the capacity to process low-confusability words in parallel across the letters (Fiset, Arguin, & McCabe, 2006). Here a series of experiments is presented investigating letter confusability effects in MAH, a patient with expressive and receptive aphasia who shows reduced reading accuracy with longer words, and DM, a relatively "pure" alexic patient. Two rehabilitation studies were employed: (i) a word-level therapy and (ii) a letter-level therapy designed to improve discrimination of individual letters. The word-level treatment produced generalised improvement to low-confusability words only, but the serial processing treatment produced improvement on both high and low confusability words. The results add support to the hypothesis that letter confusability plays a key role in letter-by-letter reading, and suggest that a rehabilitation method aimed at reducing ambiguities in letter identification may be particularly effective for treating letter-by-letter reading.
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Optimization of multicast optical networks with genetic algorithm
NASA Astrophysics Data System (ADS)
Lv, Bo; Mao, Xiangqiao; Zhang, Feng; Qin, Xi; Lu, Dan; Chen, Ming; Chen, Yong; Cao, Jihong; Jian, Shuisheng
2007-11-01
In this letter, aiming to obtain the best multicast performance of optical network in which the video conference information is carried by specified wavelength, we extend the solutions of matrix games with the network coding theory and devise a new method to solve the complex problems of multicast network switching. In addition, an experimental optical network has been testified with best switching strategies by employing the novel numerical solution designed with an effective way of genetic algorithm. The result shows that optimal solutions with genetic algorithm are accordance with the ones with the traditional fictitious play method.
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2012-01-01
The aim of this letter is to facilitate the standardisation of Abbreviated Injury Scale (AIS) codesets used to code injuries in trauma registries. We have compiled a definitive list of the changes which have been implemented between the AIS 2005 and Update 2008 versions. While the AIS 2008 codeset appears to have remained consistent since its release, we have identified discrepancies between the codesets in copies of AIS 2005 dictionaries. As a result, we recommend that use of the AIS 2005 should be discontinued in favour of the Update 2008 version. PMID:22301065
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Ringdal, Kjetil G; Hestnes, Morten; Palmer, Cameron S
2012-02-02
The aim of this letter is to facilitate the standardisation of Abbreviated Injury Scale (AIS) codesets used to code injuries in trauma registries. We have compiled a definitive list of the changes which have been implemented between the AIS 2005 and Update 2008 versions. While the AIS 2008 codeset appears to have remained consistent since its release, we have identified discrepancies between the codesets in copies of AIS 2005 dictionaries. As a result, we recommend that use of the AIS 2005 should be discontinued in favour of the Update 2008 version.
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NASA Technical Reports Server (NTRS)
Roman, N. G.; Warren, W. H., Jr.
1983-01-01
A revised and corrected version of the machine-readable catalog has been prepared. Cross identifications of the GC stars to the HD and DM catalogs have been replaced by data from the new SAO-HD-GC-DM Cross Index (Roman, Warren and Schofield 1983), including component identifications for multiple SAO entries having identical DM numbers in the SAO Catalog, supplemental Bonner Durchmusterung stars (lower case letter designations) and codes for multiple HD stars. Additional individual corrections have been incorporated based upon errors found during analyses of other catalogs.
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Hung, Yu-Han; Tseng, Chin-Hao; Hwang, Sheng-Kwang
2018-06-01
This Letter investigates an optically injected semiconductor laser for conversion from non-orthogonally to orthogonally polarized optical single-sideband modulation. The underlying mechanism relies solely on nonlinear laser characteristics and, thus, only a typical semiconductor laser is required as the key conversion unit. This conversion can be achieved for a broadly tunable frequency range up to at least 65 GHz. After conversion, the microwave phase quality, including linewidth and phase noise, is mostly preserved, and simultaneous microwave amplification up to 23 dB is feasible.
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Nanodiamonds with photostable, sub-gigahertz linewidth quantum emitters
NASA Astrophysics Data System (ADS)
Tran, Toan Trong; Kianinia, Mehran; Bray, Kerem; Kim, Sejeong; Xu, Zai-Quan; Gentle, Angus; Sontheimer, Bernd; Bradac, Carlo; Aharonovich, Igor
2017-11-01
Single-photon emitters with narrow linewidths are highly sought after for applications in quantum information processing and quantum communications. In this letter, we report on a bright, highly polarized near infrared single photon emitter embedded in diamond nanocrystals with a narrow, sub-GHz optical linewidth at 10 K. The observed zero-phonon line at ˜780 nm is optically stable under low power excitation and blue shifts as the excitation power increases. Our results highlight the prospect for using new near infrared color centers in nanodiamonds for quantum applications.
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The sensitivity of gas sensor based on single ZnO nanowire modulated by helium ion radiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Liao, L.; Lu, H. B.; Li, J. C.
2007-10-22
In this letter, we present a gas sensor using a single ZnO nanowire as a sensing unit. This ZnO nanowire-based sensor has quick and high sensitive response to H{sub 2}S in air at room temperature. It has also been found that the gas sensitivity of the ZnO nanowires could be modulated and enhanced by He{sup +} implantation at an appropriate dose. A possible explanation is given based on the modulation model of the depletion layer.
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Following insects around: tools and techniques of eighteenth-century natural history.
Terrall, Mary
2010-12-01
This paper examines the movement of the materials, ideas and practices that went into the construction of natural-historical observations in Paris and the French provinces--in particular, observations of insects. The paired notions of circulation and locality expose the complex dynamic at play in the production of knowledge about these mundane creatures. I show how the movement of things and people problematizes the notion of a single 'centre of calculation', even where a dominant figure like Réaumur was managing collections and producing authoritative texts. Réaumur was indeed managing the flow of observations, letters and specimens from his privileged vantage point in Paris, but he was not the only one doing the processing, and the objects and knowledge flowed in all directions. The paper uses correspondence among eighteenth-century naturalists of various sorts to get at the dynamics of circulation, tracing the movements of insects, bits of text or narrative, drawings, letters, questions, apparatus, books and people. My title refers to the activities of naturalists, who had to follow insects around in order to observe them, and to my own activity in following the insects in their movement through letters, conversations, specimen jars, drawings and texts. My research depends on the accumulation of details about experimental and observational practice, culled from the masses of letters that moved continually around Europe, much as the science of insects depended on the accumulation of details about insects--their physiology, habits, metamorphosis and place in the human economy and the economy of nature.
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Liu, Pou; Kantola, Kalle; Fukuda, Toshio; Arai, Fumihito
2009-05-01
We report that a series of in situ nanofabrication techniques of nanostructures, including cutting, bending and soldering of carbon nanotubes (CNTs), inside a field emission scanning electron microscope (FE-SEM) used for nanoassembly of nanostructures. The CNTs can be cut with electron beam assisted with oxygen gas. The cutting was developed for the bending of CNT, if some conditions of the cutting technique are changed. These include the increase of the acceleration voltage and/or setting the oxygen gas nozzle farther from the sample, and/or reducing the irradiation time. Using the proposed bending method angles larger than 90 degrees can be formed and the location of the kink can be set accurately. It is also shown that tungsten can be deposited on a substrate by the electron-beam-induced deposition, if the oxygen of the proposed cutting technique is replaced by W(CO)6. In this paper, these three nanofabrication methods were employed in the creation of a two dimensional (2D) nanostructure, the letters N and U, and a three dimensional (3D) nanostructure, the letter N. The 2D letters were constructed from 6 CNTs assembled on a substrate while the 3D letter N was bended from a single CNT and fixed to stand on a substrate. Based on the high performance of the proposed techniques, it is suggested that the cutting, bending, and soldering techniques inside SEM will become widely utilized in the fabrication and assembly of nanodevices and in the characterization of nanomaterials.
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Lexical access via letter naming in a profoundly alexic and anomic patient: a treatment study.
Greenwald, M L; Gonzalez Rothi, L J
1998-11-01
We report the results of a letter naming treatment designed to facilitate letter-by-letter reading in an aphasic patient with no reading ability. Patient M.R.'s anomia for written letters reflected two loci of impairment within visual naming: impaired letter activation from print (a deficit commonly seen in pure alexic patients who read letter by letter) and impaired access to phonology via semantics (documented in a severe multimodality anomia). Remarkably, M.R. retained an excellent ability to pronounce orally spelled words, demonstrating that abstract letter identities could be activated normally via spoken letter names, and also that lexical phonological representations were intact when accessed via spoken letter names. M.R.'s training in oral naming of written letters resulted in significant improvement in her oral naming of trained letters. Importantly, as M.R.'s letter naming improved, she became able to employ letter-by-letter reading as a compensatory strategy for oral word reading. M.R.'s success in letter naming and letter-by-letter reading suggests that other patients with a similar pattern of spared and impaired cognitive abilities may benefit from a similar treatment. Moreover, this study highlights the value of testing the pronunciation of orally spelled words in localizing the source of prelexical reading impairment and in predicting the functional outcome of treatment for impaired letter activation in reading.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Earl, Christopher; Might, Matthew; Bagusetty, Abhishek
This study presents Nebo, a declarative domain-specific language embedded in C++ for discretizing partial differential equations for transport phenomena on multiple architectures. Application programmers use Nebo to write code that appears sequential but can be run in parallel, without editing the code. Currently Nebo supports single-thread execution, multi-thread execution, and many-core (GPU-based) execution. With single-thread execution, Nebo performs on par with code written by domain experts. With multi-thread execution, Nebo can linearly scale (with roughly 90% efficiency) up to 12 cores, compared to its single-thread execution. Moreover, Nebo’s many-core execution can be over 140x faster than its single-thread execution.
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Earl, Christopher; Might, Matthew; Bagusetty, Abhishek; ...
2016-01-26
This study presents Nebo, a declarative domain-specific language embedded in C++ for discretizing partial differential equations for transport phenomena on multiple architectures. Application programmers use Nebo to write code that appears sequential but can be run in parallel, without editing the code. Currently Nebo supports single-thread execution, multi-thread execution, and many-core (GPU-based) execution. With single-thread execution, Nebo performs on par with code written by domain experts. With multi-thread execution, Nebo can linearly scale (with roughly 90% efficiency) up to 12 cores, compared to its single-thread execution. Moreover, Nebo’s many-core execution can be over 140x faster than its single-thread execution.
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2013-01-01
Background Primary care databases are a major source of data for epidemiological and health services research. However, most studies are based on coded information, ignoring information stored in free text. Using the early presentation of rheumatoid arthritis (RA) as an exemplar, our objective was to estimate the extent of data hidden within free text, using a keyword search. Methods We examined the electronic health records (EHRs) of 6,387 patients from the UK, aged 30 years and older, with a first coded diagnosis of RA between 2005 and 2008. We listed indicators for RA which were present in coded format and ran keyword searches for similar information held in free text. The frequency of indicator code groups and keywords from one year before to 14 days after RA diagnosis were compared, and temporal relationships examined. Results One or more keyword for RA was found in the free text in 29% of patients prior to the RA diagnostic code. Keywords for inflammatory arthritis diagnoses were present for 14% of patients whereas only 11% had a diagnostic code. Codes for synovitis were found in 3% of patients, but keywords were identified in an additional 17%. In 13% of patients there was evidence of a positive rheumatoid factor test in text only, uncoded. No gender differences were found. Keywords generally occurred close in time to the coded diagnosis of rheumatoid arthritis. They were often found under codes indicating letters and communications. Conclusions Potential cases may be missed or wrongly dated when coded data alone are used to identify patients with RA, as diagnostic suspicions are frequently confined to text. The use of EHRs to create disease registers or assess quality of care will be misleading if free text information is not taken into account. Methods to facilitate the automated processing of text need to be developed and implemented. PMID:23964710
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Summary statistics in the attentional blink.
McNair, Nicolas A; Goodbourn, Patrick T; Shone, Lauren T; Harris, Irina M
2017-01-01
We used the attentional blink (AB) paradigm to investigate the processing stage at which extraction of summary statistics from visual stimuli ("ensemble coding") occurs. Experiment 1 examined whether ensemble coding requires attentional engagement with the items in the ensemble. Participants performed two sequential tasks on each trial: gender discrimination of a single face (T1) and estimating the average emotional expression of an ensemble of four faces (or of a single face, as a control condition) as T2. Ensemble coding was affected by the AB when the tasks were separated by a short temporal lag. In Experiment 2, the order of the tasks was reversed to test whether ensemble coding requires more working-memory resources, and therefore induces a larger AB, than estimating the expression of a single face. Each condition produced a similar magnitude AB in the subsequent gender-discrimination T2 task. Experiment 3 additionally investigated whether the previous results were due to participants adopting a subsampling strategy during the ensemble-coding task. Contrary to this explanation, we found different patterns of performance in the ensemble-coding condition and a condition in which participants were instructed to focus on only a single face within an ensemble. Taken together, these findings suggest that ensemble coding emerges automatically as a result of the deployment of attentional resources across the ensemble of stimuli, prior to information being consolidated in working memory.
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Déruaz, Anouk; Goldschmidt, Mira; Whatham, Andrew R; Mermoud, Christophe; Lorincz, Erika N; Schnider, Armin; Safran, Avinoam B
2006-11-23
Reading with a central scotoma involves the use of preferred retinal loci (PRLs) that enable both letter resolution and global viewing of word. Spontaneously developed PRLs however often privilege spatial resolution and, as a result, visual span is commonly limited by the position of the scotoma. In this study we designed and performed the pilot trial of a training procedure aimed at modifying oculomotor behavior in subjects with central field loss. We use an additional fixation point which, when combined with the initial PRL, allows the fulfillment of both letter resolution and global viewing of words. The training procedure comprises ten training sessions conducted with the scanning laser ophthalmoscope (SLO). Subjects have to read single letters and isolated words varying in length, by combining the use of their initial PRL with the one of an examiner's selected trained retinal locus (TRL). We enrolled five subjects to test for the feasibility of the training technique. They showed stable maculopathy and persisting major reading difficulties despite previous orthoptic rehabilitation. We evaluated ETDRS visual acuity, threshold character size for single letters and isolated words, accuracy for paragraphed text reading and reading strategies before, immediately after SLO training, and three months later. Training the use of multiple PRLs in patients with central field loss is feasible and contributes to adapt oculomotor strategies during reading related tasks. Immediately after SLO training subjects used in combination with their initial PRL the examiner's selected TRL and other newly self-selected PRLs. Training gains were also reflected in ETDRS acuity, threshold character size for words of different lengths and in paragraphed text reading. Interestingly, subjects benefited variously from the training procedure and gains were retained differently as a function of word length. We designed a new procedure for training patients with central field loss using scanning laser ophthalmoscopy. Our initial results on the acquisition of newly self-selected PRLs and the development of new oculomotor behaviors suggest that the procedure aiming primarily at developing an examiner's selected TRL might have initiated a more global functional adaptation process.
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Letter names and phonological awareness help children to learn letter-sound relations.
Cardoso-Martins, Cláudia; Mesquita, Tereza Cristina Lara; Ehri, Linnea
2011-05-01
Two experimental training studies with Portuguese-speaking preschoolers in Brazil were conducted to investigate whether children benefit from letter name knowledge and phonological awareness in learning letter-sound relations. In Experiment 1, two groups of children were compared. The experimental group was taught the names of letters whose sounds occur either at the beginning (e.g., the letter /be/) or in the middle (e.g., the letter /'eli/) of the letter name. The control group was taught the shapes of the letters but not their names. Then both groups were taught the sounds of the letters. Results showed an advantage for the experimental group, but only for beginning-sound letters. Experiment 2 investigated whether training in phonological awareness could boost the learning of letter sounds, particularly middle-sound letters. In addition to learning the names of beginning- and middle-sound letters, children in the experimental group were taught to categorize words according to rhyme and alliteration, whereas controls were taught to categorize the same words semantically. All children were then taught the sounds of the letters. Results showed that children who were given phonological awareness training found it easier to learn letter sounds than controls. This was true for both types of letters, but especially for middle-sound letters. Copyright © 2011. Published by Elsevier Inc.
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Schubert, Teresa; Reilhac, Caroline; McCloskey, Michael
2018-06-01
How are reading and writing related? In this study, we address the relationship between letter identification and letter production, uncovering a link in which production information can be used to identify letters presented dynamically. By testing an individual with a deficit in letter identification, we identified a benefit which would be masked by ceiling effects in unimpaired readers. In Experiment 1 we found that letter stimuli defined by the direction of dot motion (tiny dots within letter move leftward, background dots move rightward) provided no advantage over static letters. In Experiment 2, we tested dynamic stimuli in which the letter shapes emerged over time: drawn as they would be written, drawn in reverse, or with the letter shape filled in randomly. Improved identification was observed only for letters drawn as they are typically written. These results demonstrate that information about letter production can be integrated into letter identification, and point to bi-directional connections between stored letter production information (used for writing) and abstract letter identity representations (used in both reading and writing). The links from stored production information to abstract letter identities allow the former to activate the latter. We also consider the implications of our results for remediation of acquired letter identification deficits, including letter-drawing treatments and the underlying cause of their efficacy. Copyright © 2018 Elsevier Ltd. All rights reserved.
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Bočková, Martina; Chládek, Jan; Jurák, Pavel; Halámek, Josef; Štillová, Klára; Baláž, Marek; Chrastina, Jan; Rektor, Ivan
2015-03-01
Cognitive adverse effects were reported after the deep brain stimulation (DBS) of the anterior nucleus of the thalamus (AN) in epilepsy. As the AN may have an influence on widespread neocortical networks, we hypothesized that the AN, in addition to its participation in memory processing, may also participate in cognitive activities linked with the frontal neocortical structures. The aim of this study was to investigate whether the AN might participate in complex motor-cognitive activities. Three pharmacoresistant epilepsy patients implanted with AN-DBS electrodes performed two tasks involving the writing of single letters: (1) copying letters from a monitor; and (2) writing of any letter other than that appearing on the monitor. The cognitive load of the second task was increased. The task-related oscillatory changes and evoked potentials were assessed. Local event-related alpha and beta desynchronization were more expressed during the second task while the lower gamma synchronization decreased. The local field event-related potentials were elicited by the two tasks without any specific differences. The AN participates in cognitive networks processing complex motor-cognitive tasks. Attention should be paid to executive functions in subjects undergoing AN-DBS.
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Directed educational training improves coding and billing skills for residents.
Benke, James R; Lin, Sandra Y; Ishman, Stacey L
2013-03-01
To determine if coding and billing acumen improves after a single directed educational training session. Case-control series. Fourteen otolaryngology practitioners including trainees each completed two clinical scenarios before and after a directed educational session covering basic skills and common mistakes in otolaryngology billing and coding. Ten practitioners had never coded before; while, four regularly billed and coded in a clinical setting. Individuals with no previous billing experience had a mean score of 54% (median 55%) before the educational session which was significantly lower than that of the experienced billers who averaged 82% (median 83%, p=0.002). After the educational billing and coding session, the inexperienced billers mean score improved to 62% (median, 67%) which was still statistically lower than that of the experienced billers who averaged 76% (median 75%, p=0.039). The inexperienced billers demonstrated a significant improvement in their total score after the intervention (P=0.019); however, the change observed in experienced billers before and after the educational intervention was not significant (P=0.469). Billing and coding skill was improved after a single directed education session. Residents, who are not responsible for regular billing and coding, were found to have the greatest improvement in skill. However, providers who regularly bill and code had no significant improvement after this session. These data suggest that a single 90min billing and coding education session is effective in preparing those with limited experience to competently bill and code. Copyright © 2012. Published by Elsevier Ireland Ltd.
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Fast decoding techniques for extended single-and-double-error-correcting Reed Solomon codes
NASA Technical Reports Server (NTRS)
Costello, D. J., Jr.; Deng, H.; Lin, S.
1984-01-01
A problem in designing semiconductor memories is to provide some measure of error control without requiring excessive coding overhead or decoding time. For example, some 256K-bit dynamic random access memories are organized as 32K x 8 bit-bytes. Byte-oriented codes such as Reed Solomon (RS) codes provide efficient low overhead error control for such memories. However, the standard iterative algorithm for decoding RS codes is too slow for these applications. Some special high speed decoding techniques for extended single and double error correcting RS codes. These techniques are designed to find the error locations and the error values directly from the syndrome without having to form the error locator polynomial and solve for its roots.
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ERIC Educational Resources Information Center
Evans, Mary Ann; Bell, Michelle; Shaw, Deborah; Moretti, Shelley; Page, Jodi
2006-01-01
In this study 149 kindergarten children were assessed for knowledge of letter names and letter sounds, phonological awareness, and cognitive abilities. Through this it examined child and letter characteristics influencing the acquisition of alphabetic knowledge in a naturalistic context, the relationship between letter-sound knowledge and…
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Single-channel voice-response-system program documentation volume I : system description
DOT National Transportation Integrated Search
1977-01-01
This report documents the design and implementation of a Voice Response System (VRS) using Adaptive Differential Pulse Code Modulation (ADPCM) voice coding. Implemented on a Digital Equipment Corporation PDP-11/20,R this VRS system supports a single ...
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Effects of Letter-Identification Training on Letter Naming in Prereading Children
ERIC Educational Resources Information Center
Hayashi, Yusuke; Schmidt, Anna C.; Saunders, Kathryn J.
2013-01-01
Three prereading children who named 0 to 3 of 20 targeted letters were taught to select the 20 printed letters when they heard spoken letter names. For all participants, letter-identification training resulted in naming for the majority of letters.
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-01
... accepted. Submissions must be submitted in English by the applicable deadlines set forth in this notice. To... Intent to Testify,'' ``Pre-hearing brief'' or a ``Post hearing brief.'' Submissions must be in English, with the total submission not to exceed 30 single-spaced standard letter-size pages in 12-point type...
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Effects of Head Rotation on Space- and Word-Based Reading Errors in Spatial Neglect
ERIC Educational Resources Information Center
Reinhart, Stefan; Keller, Ingo; Kerkhoff, Georg
2010-01-01
Patients with right hemisphere lesions often omit or misread words on the left side of a text or the beginning letters of single words which is termed neglect dyslexia (ND). Two types of reading errors are typically observed in ND: omissions and word-based reading errors. The prior are considered as space-based omission errors on the…
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ERIC Educational Resources Information Center
Weinzierl, Christiane; Kerkhoff, Georg; van Eimeren, Lucia; Keller, Ingo; Stenneken, Prisca
2012-01-01
Unilateral spatial neglect frequently involves a lateralised reading disorder, neglect dyslexia (ND). Reading of single words in ND is characterised by left-sided omissions and substitutions of letters. However, it is unclear whether the distribution of error types and positions within a word shows a unique pattern of ND when directly compared to…
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ERIC Educational Resources Information Center
Butler, E. A.
A man's work shapes him far more profoundly than any other single influence in his life. There are many ways in which a person can find himself in the wrong job, but time, thought, and action invested before accepting a position can help the job seeker avoid many of the common errors. The introductory letter and resume can make or break a career.…
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1994-05-01
1979. 110 42. Williams, A.E., and Saravane, I., Debris Chlaraiatiaon SUt&y NRL Letter Rleport 4680-196,1990. 43. Weanzel, A.B., and Dean , J.K., Behind...Commerce, National Bureau of Standards, Washington, D.C., 1971. 52. Stull , D.X, and Sinke, G.C., *Thermodynamic Properties of the Elements", in Advances in
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-19
... manufactured for BioCryst Pharmaceuticals, Inc. (BioCryst) for intravenous (IV) administration in certain adult... peramivir is as follows: Peramivir injection: 200mg/20mL (10 mg/mL) single use vial manufactured for BioCryst Pharmaceuticals, Inc. (BioCryst). (See Section IV.D.3. of this letter). 1. The above peramivir...
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ERIC Educational Resources Information Center
Reed, Deborah K.
2013-01-01
This study sought to determine the effects of explicit phonics instruction and sight word instruction on the letter-sound identification and word reading of 13- to 15-year-old English language learners in the eighth grade who were identified as having intellectual disabilities (ID). Using a randomized single-subject design, four Hispanic students…
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[Computer-supported patient history: a workplace analysis].
Schubiger, G; Weber, D; Winiker, H; Desgrandchamps, D; Imahorn, P
1995-04-29
Since 1991, an extensive computer network has been developed and implemented at the Cantonal Hospital of Lucerne. The medical applications include computer aided management of patient charts, medical correspondence, and compilation of diagnosis statistics according to the ICD-9 code. In 1992, the system was introduced as a pilot project in the departments of pediatrics and pediatric surgery of the Lucerne Children's Hospital. This new system has been prospectively evaluated using a workplace analysis. The time taken to complete patient charts and surgical reports was recorded for 14 days before and after the introduction of the computerized system. This analysis was performed for both physicians and secretarial staff. The time delay between the discharge of the patient and the mailing of the discharge letter to the family doctor was also recorded. By conventional means, the average time for the physician to generate a patient chart (26 minutes, n = 119) was slightly lower than the time needed with the computer system (28 minutes, n = 177). However, for a discharge letter, the time needed by the physician was reduced by one third with the computer system and by more than one half for the secretarial staff (32 and 66 minutes conventionally; 22 and 24 minutes respectively with the computer system; p < 0.0001). The time required for the generation of surgical reports was reduced from 17 to 13 minutes per patient and the processing time by secretaries from 37 to 14 minutes. The time delay between the discharge of the patient and the mailing of the discharge letter was reduced by 50% from 7.6 to 3.9 days.(ABSTRACT TRUNCATED AT 250 WORDS)
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Do children with grapheme-colour synaesthesia show cognitive benefits?
Simner, Julia; Bain, Angela E
2018-02-01
Grapheme-colour synaesthesia is characterized by conscious and consistent associations between letters and colours, or between numbers and colours (e.g., synaesthetes might see A as red, 7 as green). Our study explored the development of this condition in a group of randomly sampled child synaesthetes. Two previous studies (Simner & Bain, 2013, Frontiers in Human Neuroscience, 7, 603; Simner, Harrold, Creed, Monro, & Foulkes, 2009, Brain, 132, 57) had screened over 600 primary school children to find the first randomly sampled cohort of child synaesthetes. In this study, we evaluate this cohort to ask whether their synaesthesia is associated with a particular cognitive profile of strengths and/or weaknesses. We tested our child synaesthetes at age 10-11 years in a series of cognitive tests, in comparison with matched controls and baseline norms. One previous study (Green & Goswami, 2008, Cognition, 106, 463) had suggested that child synaesthetes might perform differently to non-synaesthetes in such tasks, although those participants may have been a special type of population independent of their synaesthesia. In our own study of randomly sampled child synaesthetes, we found no significant advantages or disadvantages in a receptive vocabulary test and a memory matrix task. However, we found that synaesthetes demonstrated above-average performance in a processing-speed task and a near-significant advantage in a letter-span task (i.e., memory/recall task of letters). Our findings point to advantages for synaesthetes that go beyond those expected from enhanced coding accounts and we present the first picture of the broader cognitive profile of a randomly sampled population of child synaesthetes. © 2017 The British Psychological Society.
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From perceptual to lexico-semantic analysis--cortical plasticity enabling new levels of processing.
Schlaffke, Lara; Rüther, Naima N; Heba, Stefanie; Haag, Lauren M; Schultz, Thomas; Rosengarth, Katharina; Tegenthoff, Martin; Bellebaum, Christian; Schmidt-Wilcke, Tobias
2015-11-01
Certain kinds of stimuli can be processed on multiple levels. While the neural correlates of different levels of processing (LOPs) have been investigated to some extent, most of the studies involve skills and/or knowledge already present when performing the task. In this study we specifically sought to identify neural correlates of an evolving skill that allows the transition from perceptual to a lexico-semantic stimulus analysis. Eighteen participants were trained to decode 12 letters of Morse code that were presented acoustically inside and outside of the scanner environment. Morse code was presented in trains of three letters while brain activity was assessed with fMRI. Participants either attended to the stimulus length (perceptual analysis), or evaluated its meaning distinguishing words from nonwords (lexico-semantic analysis). Perceptual and lexico-semantic analyses shared a mutual network comprising the left premotor cortex, the supplementary motor area (SMA) and the inferior parietal lobule (IPL). Perceptual analysis was associated with a strong brain activation in the SMA and the superior temporal gyrus bilaterally (STG), which remained unaltered from pre and post training. In the lexico-semantic analysis post learning, study participants showed additional activation in the left inferior frontal cortex (IFC) and in the left occipitotemporal cortex (OTC), regions known to be critically involved in lexical processing. Our data provide evidence for cortical plasticity evolving with a learning process enabling the transition from perceptual to lexico-semantic stimulus analysis. Importantly, the activation pattern remains task-related LOP and is thus the result of a decision process as to which LOP to engage in. © 2015 The Authors. Human Brain Mapping Published by Wiley Periodicals, Inc.
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From perceptual to lexico‐semantic analysis—cortical plasticity enabling new levels of processing
Schlaffke, Lara; Rüther, Naima N.; Heba, Stefanie; Haag, Lauren M.; Schultz, Thomas; Rosengarth, Katharina; Tegenthoff, Martin; Bellebaum, Christian
2015-01-01
Abstract Certain kinds of stimuli can be processed on multiple levels. While the neural correlates of different levels of processing (LOPs) have been investigated to some extent, most of the studies involve skills and/or knowledge already present when performing the task. In this study we specifically sought to identify neural correlates of an evolving skill that allows the transition from perceptual to a lexico‐semantic stimulus analysis. Eighteen participants were trained to decode 12 letters of Morse code that were presented acoustically inside and outside of the scanner environment. Morse code was presented in trains of three letters while brain activity was assessed with fMRI. Participants either attended to the stimulus length (perceptual analysis), or evaluated its meaning distinguishing words from nonwords (lexico‐semantic analysis). Perceptual and lexico‐semantic analyses shared a mutual network comprising the left premotor cortex, the supplementary motor area (SMA) and the inferior parietal lobule (IPL). Perceptual analysis was associated with a strong brain activation in the SMA and the superior temporal gyrus bilaterally (STG), which remained unaltered from pre and post training. In the lexico‐semantic analysis post learning, study participants showed additional activation in the left inferior frontal cortex (IFC) and in the left occipitotemporal cortex (OTC), regions known to be critically involved in lexical processing. Our data provide evidence for cortical plasticity evolving with a learning process enabling the transition from perceptual to lexico‐semantic stimulus analysis. Importantly, the activation pattern remains task‐related LOP and is thus the result of a decision process as to which LOP to engage in. Hum Brain Mapp 36:4512–4528, 2015. © 2015 The Authors. Human Brain Mapping Published byWiley Periodicals, Inc. PMID:26304153
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NASA Astrophysics Data System (ADS)
Qin, Guoxuan; Yuan, Hao-Chih; Celler, George K.; Ma, Jianguo; Ma, Zhenqiang
2011-10-01
This letter presents radio frequency (RF) characterization of flexible microwave switches using single-crystal silicon nanomembranes (SiNMs) on plastic substrate under various uniaxial mechanical tensile bending strains. The flexible switches shows significant/negligible performance enhancement on strains under on/off states from dc to 10 GHz. Furthermore, an RF/microwave strain equivalent circuit model is developed and reveals the most influential factors, and un-proportional device parameters change with bending strains. The study demonstrates that flexible microwave single-crystal SiNM switches, as a simple circuit example towards the goal of flexible monolithic microwave integrated circuits, can be properly operated and modeled under mechanical bending conditions.