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Sample records for siringomielia experiencia 2000-2008

  1. Trends in opioid analgesics consumption, Israel, 2000-2008.

    PubMed

    Ponizovsky, Alexander M; Marom, Eli; Zeldin, Alexander; Cherny, Nathan I

    2011-02-01

    To describe trends in opioid consumption in Israel (morphine, methadone, oxycodone, pethidine, fentanyl, buprenorphine, codeine, and dextropropoxyphene) over the 9 years, 2000-2008, and to explore explanations for changes in consumption, in amounts and the pattern. Data for the 2000-2008 period (all treatment settings, private and public) were drawn from the database maintained by the Israel Ministry of Health's Pharmaceutical Administration. The data were converted into a defined daily dose (DDD)/1,000 inhabitants/day. Consumption of the five strong opioids (requiring a special prescription form) increased by 47%, from 2.46 DDD/1,000 inhabitants per day in 2000 to 3.61 DDD/1,000 inhabitants per day in 2008. This rise was mainly the result of a 4-fold increase in fentanyl consumption from 0.32 DDD/1,000 inhabitants per day in 2000 to 1.28 DDD/1,000 inhabitants per day in 2008. Oxycodone and methadone consumption levels increased moderately, and buprenorphine and dextropropoxyphene consumption rose drastically, whereas morphine, pethidine, and codeine use significantly fell. There has been a modest increase in opioid consumption in the years 2000-2008. This has been associated with substantial changes in the pattern of differential opioid prescribing characterized by increased prescription of oxycodone, fentanyl, buprenorphine, and dextropropoxyphene, and decreases in morphine, pethidine, and codeine.

  2. Prevalence and Mortality of Melanoma in Oklahoma Among Racial Groups, 2000-2008

    PubMed Central

    Baldwin, Jonathan; Janitz, Amanda E.; Erb-Alvarez, Julie; Snider, Cuyler; Campbell, Janis E.

    2016-01-01

    Introduction This study assessed the period prevalence (2000-2008) and mortality rates of melanoma, in Oklahoma, among different racial/ethnic strata. Methods We analyzed incident cases of melanoma from 2000-2008 from the Oklahoma Central Cancer Registry and determined disease duration using Kaplan-Meier survival analysis to calculate period prevalence of melanoma in Oklahoma. Using a series of Chi-Square tests, we compared period prevalence and mortality rates among the racial groups and compared mortality between Oklahoma and the US. Results White non-Hispanics in Oklahoma have the highest period prevalence (p<0.0001) among the racial strata. American Indian or Alaska Native (AI/AN) individuals have the second highest period prevalence in Oklahoma (p<0.0001). Furthermore, white non-Hispanics (p<0.0001) and AI/AN individuals (p=0.0003) in Oklahoma had higher mortality rates compared to the US. Conclusions There are disparities in the prevalence and mortality of melanoma among the AI/AN population in Oklahoma, and prevention and education programs should focus on this population. PMID:27885301

  3. Cancer incidence and survival in adolescents and young adults in France, 2000-2008.

    PubMed

    Desandes, Emmanuel; Lacour, Brigitte; Belot, Aurélien; Molinie, Florence; Delafosse, Patricia; Tretarre, Brigitte; Velten, Michel; Sauleau, Erik-André; Woronoff, Anne-Sophie; Guizard, Anne-Valérie; Ganry, Olivier; Bara, Simona; Grosclaude, Pascale; Troussard, Xavier; Bouvier, Véronique; Brugieres, Laurence; Clavel, Jacqueline

    2013-05-01

    This study aimed to describe cancer incidence (2000-2008) and survival (2000-2004) in France in adolescents and young adults (AYA). All cases of cancer diagnosed in 15-24 years, recorded by all French population-based registries (14% of the French population), over the 2000-2008 period, were included. Incidence change over time was described with the conventional annual percentage change (cAPC). The survival of cases diagnosed (2000-2004) was estimated using Kaplan-Meier method. A total of 1022 in adolescents and 1396 in young adults were diagnosed. Overall incidence rates were 219.4/10(6) in 15-19 year olds and 293.1/10(6) in 20-24 year olds. The most frequently diagnosed cancers in male AYA were malignant gonadal germ-cell tumors and Hodgkin's disease, and were melanoma, thyroid carcinoma, and Hodgkin's disease in females. The age-standardized rates appeared stable over time in AYA, with a cAPC of +2.0% (P = 0.68). The 5-year overall survival for all cancers was different between genders and age groups, with 78.8% (95%CI: 75.6-82.0) for males and 85.2% (95%CI: 82.2-88.1) for females (P = 0.01), and 78.5% (95%CI: 75.0-82.1) in 15-19 year olds and 84.3% (95% CI: 81.6-87.0) in 20-24 year olds (P = 0.02). Noteworthy, the frequency and the distribution of tumor types in AYA are unique and different from the observed at any other age group. Survival in French AYA has improved over time. Epidemiological data might reflect major trends in the risk factors and preventive interventions. Thus, further research into etiology of cancers affecting AYA should become key priorities for cancer control among AYA.

  4. National Trends in Surgical Therapy for Benign Prostatic Hyperplasia in the United States (2000-2008)

    PubMed Central

    Malaeb, Bahaa S; Yu, Xinhua; McBean, A. Marshall; Elliott, Sean P

    2012-01-01

    Introduction The rate of utilization of thermotherapy and laser therapy in the surgical treatment of benign prostatic hyperplasia (BPH) has been changing over the past decade in conjunction with a steady decrease of TURP. We now report an update of the change in utilization trends for different surgical treatments of BPH among the United States Medicare population data 2000-2008. Methods Using the 100% Medicare carrier file for the years 2000-2008 we calculated counts and population-adjusted rates of BPH surgery. Rates of TURP, thermotherapy and laser-utilizing modalities were calculated and compared in relation to age, race, clinical setting, and reimbursement. Results After years of a steady rise, the total rate of all BPH procedures peaked in 2005 at 1,078/100,000 then declined by 15.4% to 912/100,000 in 2008. TURP rates continued to decline from 670 in 2000 to 351/100,000 in 2008. Rates of TUMT peaked in 2006 at 266/100,000 then declined 26% in 2008. Laser vaporization almost completely replaced laser coagulation and in 2008, was the most commonly performed procedure second to TURP with the majority performed as outpatient procedures (70%) and an increasing percentage in the office (12%). Men between ages 70-75 had the highest rate of procedures. Reimbursement rates correlate with the use of some but not all procedures. Racial disparities reported previously appear to have resolved. Conclusions Surgical treatment of BPH continues to change rapidly. TURP continues to decline and laser vaporization is the fastest growing modality. There is a big shift towards outpatient/office procedures. Reimbursement rates do not appear to have a consistent effect on utilization. PMID:22546389

  5. Mortality trends from hypertension in Mexico by socioeconomic region and state, 2000-2008.

    PubMed

    Sánchez-Barriga, Juan Jesús

    2012-08-01

    To determine mortality trends from hypertension in Mexico nationwide, by state, by socioeconomic region, and by sex and to establish an association between education, state of residence, and socioeconomic region with mortality from hypertension in 2000-2008. Records of mortality associated with hypertension for 2000-2008 were obtained from the National Information System of the Secretariat of Health. This information is generated by the National Institute of Statistics, Geography and Informatics through death certificates issued throughout the country. International Classification of Diseases, 10th Revision, codes corresponding to the basic cause of death from hypertension were identified. Rates of mortality nationwide, by state, and by socioeconomic region were calculated. The strength of association (obtained by Poisson regression) between states where individuals resided, socioeconomic regions, and education with mortality from hypertension was determined. The seven socioeconomic regions were elaborated by the National Institute of Statistics, Geography and Informatics and include the 31 states and Mexico City according to indicators that are related to well-being such as education, occupation, health, housing, and employment. Individuals who did not complete elementary school had a higher risk of dying from hypertension than people with more or no education [relative risk (RR) 1.462, 95% confidence interval (CI) 1.442-1.482]. Mexico City, Oaxaca, and region 7 had the strongest association with dying from hypertension [Mexico City: RR 2.6, CI 2.1-3.2 (2000) and RR 2.5, CI 2.1-3.1 (2005); Oaxaca: RR 2.4, CI2.0-3.0 (2006) and RR 2.7, CI2.3-3.3 (2008); region 7: RR 1.58, CI 1.45-1.72 (2000) and RR 1.25, CI 1.17-1.34 (2008)]. Age-adjusted mortality rates per 100 000 inhabitants who died from hypertension increased from 15.7 to 18.5 between 2000 and 2008, taking the world population age distribution as standard. Mortality was higher in women than in men and in

  6. Comparison of atmospheric mercury (Hg) among Korea, Japan, China and Taiwan during 2000-2008.

    PubMed

    Fang, Guor-Cheng; Wu, Yuh-Shen; Chang, Tai-Hua

    2009-03-15

    The paper reviewed studies about total gaseous mercury, atmospheric particulate of mercury and average dry deposition fluxes of mercury in Korea, Japan, China and Taiwan. This study compared sample collection and analytical methods for mercury in Asian countries. Analytical results indicated that the primary mercury sources are anthropogenic source (for example coal burning) and high temperature processes. This study also elucidates the sources, analytical tools, and the average concentrations for atmospheric mercury (Hg) for these Asian countries during 2000-2008. This study indicated that the total gaseous mercury concentrations were higher in urban area than that in suburban area in Asian countries (Korea, Japan, China and Taiwan). As for the seasonal variations, in general, the average total gaseous mercury concentrations were higher in winter than that in summer especially in China. In addition, the average total gaseous mercury concentrations were higher in mining areas than that in the rest of the other areas. And the total gaseous mercury concentrations were decreasing as this distance increasing. These phenomena revealed that the total gaseous mercury concentrations are reduced by long-distance transportation especially in the main land of China.

  7. Molecular epidemiology of tuberculosis in Kaohsiung City located at southern Taiwan, 2000-2008.

    PubMed

    Chen, Yih-Yuan; Chang, Jia-Ru; Kuo, Shu-Chen; Tseng, Fan-Chen; Huang, Wei-Chen; Huang, Tsi-Shu; Chen, Yao-Shen; Chiueh, Tzong-Shi; Sun, Jun-Ren; Su, Ih-Jen; Dou, Horng-Yunn

    2015-01-01

    We present the first comprehensive analysis of Mycobacterium tuberculosis (MTB) isolates circulating in southern Taiwan. In this 9-year population-based study, the TB situation in the Kaohsiung region was characterized by genotypic analysis of 421 MTB isolates. All 421 isolates of MTB were analyzed by spoligotyping and MIRU-VNTR typing. Drug-resistance patterns were also analyzed. The percentage of EAI (East African-Indian) strains increased across sampling years (2000-2008) in southern Taiwan, whereas the proportion of Beijing lineages remained unchanged. Clustering was more frequent with EAI genotype infections (odds ratio = 3.6, p<0.0001) when compared to Beijing genotypes. Notably, MTB resistance to streptomycin (STR) had significantly increased over time, but resistance to other antibiotics, including multidrug resistance, had not. Three major genes (gidB, rpsL and rrs) implicated in STR resistance were sequenced and specific mutations identified. This study revealed that EAI strains were highly transmissible and that STR resistance has increased between 2000 and 2008 in Kaohsiung, Taiwan.

  8. Water balance of forest and semi natural areas in Hungary (2000-2008)

    NASA Astrophysics Data System (ADS)

    Csáki, Péter

    2017-04-01

    Water balance of forest and semi natural areas in Hungary was analyzed using remote-sensing based evapotranspiration (ET ) maps (1ṡ1 km spatial resolution) by CREMAP model over the 2000-2008 period. Recharge (R) was calculated as the difference of precipitation and evapotranspiration: R = P - ET . For Hungary, the mean annual ET and R in the percentage of the mean annual precipitation were about 90 percent and 10 percent, respectively. ET and R were analyzed in the context of land cover types (artificial surfaces, agricultural areas, forest and semi natural areas, wetlands, water bodies), based on Corine Land Cover 2006. As the ET and R maps have 1 km2 while the land cover map has higher resolution, a number of ET and R pixels would be calculated to more than one land cover types. Thus, there were selected only the pixels that have 90 percent of their area belong to only one land cover type ("clear pixels"). For forest and semi natural areas 4424 "clear pixels" were selected. The ET and R of forest and semi natural areas were analyzed by regions, in the context of groundwater depth, soil texture and leaf area index (LAI). Among the regions, Little Plain (riparian forest ecosystems) presented the highest ET mean (633 mm), while Southern Transdanubia (mostly sandy areas with good infiltration capacity) presented the highest R mean (106 mm) for forests. An interesting phenomenon that, in the case of forests (especially for the Great Plain region), an increasing ET tendency can be detected with the groundwater depth, down to ten meters. This research has been partly supported by the Agroclimate.2 VKSZ_12-1-2013-0034 project.

  9. Mentoring programs for medical students - a review of the PubMed literature 2000 - 2008

    PubMed Central

    2010-01-01

    Background Although mentoring is acknowledged as a key to successful and satisfying careers in medicine, formal mentoring programs for medical students are lacking in most countries. Within the framework of planning a mentoring program for medical students at Zurich University, an investigation was carried out into what types of programs exist, what the objectives pursued by such programs are, and what effects are reported. Methods A PubMed literature search was conducted for 2000 - 2008 using the following keywords or their combinations: mentoring, mentoring program, medical student, mentor, mentee, protégé, mentorship. Although a total of 438 publications were identified, only 25 papers met the selection criteria for structured programs and student mentoring surveys. Results The mentoring programs reported in 14 papers aim to provide career counseling, develop professionalism, increase students' interest in research, and support them in their personal growth. There are both one-to-one and group mentorships, established in the first two years of medical school and continuing through graduation. The personal student-faculty relationship is important in that it helps students to feel that they are benefiting from individual advice and encourages them to give more thought to their career choices. Other benefits are an increase in research productivity and improved medical school performance in general. Mentored students also rate their overall well-being as higher. - The 11 surveys address the requirements for being an effective mentor as well as a successful mentee. A mentor should empower and encourage the mentee, be a role model, build a professional network, and assist in the mentee's personal development. A mentee should set agendas, follow through, accept criticism, and be able to assess performance and the benefits derived from the mentoring relationship. Conclusion Mentoring is obviously an important career advancement tool for medical students. In Europe

  10. Evaluation of net ecosystem production (2000-2008) for potential grassland biofuel feedstock sites in the Greater Platte River Basin

    NASA Astrophysics Data System (ADS)

    Gu, Y.; Wylie, B. K.; Zhang, L.

    2011-12-01

    Net Ecosystem Production (NEP) is a measure of net carbon accumulation by ecosystems and is an important variable for assessing and understanding the terrestrial carbon cycle and global climate change. We developed a 9-year (2000-2008) time series of NEP data for grasslands within the Great Plains based on flux tower observations, satellite remote sensing, biophysical and climate conditions, and weather data. In this study, we assessed a 9-year time series of NEP in the Greater Platte River Basin to investigate the historical trends of carbon flux (i.e., NEP) for sites possibly suitable for biofuel expansion (productive grasslands) and sites not suitable for biofuel expansion (less productive or degraded grasslands). The suitability of sites was identified using our dynamic modeling of ecosystem performance method. The average annual NEP for sites that were suitable for biofuel feedstock production was from 71 to 169 g C m-2 year-1 during 2000-2008, indicating a strong carbon sink (i.e., more carbon is stored than released) in these areas. The average annual NEP for sites that were not suitable for biofuel feedstock production was from -47 to 69 g C m-2 year-1 during 2000-2008, showing a weak carbon source or a weak carbon sink in these areas. The 9-year accumulated NEP was 200 g C m-2 for the non-suitable areas (a weak carbon sink) and 1166 g C m-2 for the suitable areas (a strong carbon sink). These results demonstrate that our dynamic modeling of ecosystem performance method can identify sites desirable for biofuel feedstock development. Results from this study provide useful information for land managers and decision makers to make optimal land use decisions regarding biofuel feedstock development and sustainability.

  11. Remotely sensed forest cover loss shows high spatial and temporal variation across Sumatera and Kalimantan, Indonesia 2000-2008

    NASA Astrophysics Data System (ADS)

    Broich, Mark; Hansen, Matthew; Stolle, Fred; Potapov, Peter; Arunarwati Margono, Belinda; Adusei, Bernard

    2011-01-01

    The Indonesian islands of Sumatera and Kalimantan (the Indonesian part of the island of Borneo) are a center of significant and rapid forest cover loss in the humid tropics with implications for carbon dynamics, biodiversity conservation, and local livelihoods. The aim of our research was to analyze and interpret annual trends of forest cover loss for different sub-regions of the study area. We mapped forest cover loss for 2000-2008 using multi-resolution remote sensing data from the Landsat enhanced thematic mapper plus (ETM +) and moderate resolution imaging spectroradiometer (MODIS) sensors and analyzed annual trends per island, province, and official land allocation zone. The total forest cover loss for Sumatera and Kalimantan 2000-2008 was 5.39 Mha, which represents 5.3% of the land area and 9.2% of the year 2000 forest cover of these two islands. At least 6.5% of all mapped forest cover loss occurred in land allocation zones prohibiting clearing. An additional 13.6% of forest cover loss occurred where clearing is legally restricted. The overall trend of forest cover loss increased until 2006 and decreased thereafter. The trends for Sumatera and Kalimantan were distinctly different, driven primarily by the trends of Riau and Central Kalimantan provinces, respectively. This analysis shows that annual mapping of forest cover change yields a clearer picture than a one-time overall national estimate. Monitoring forest dynamics is important for national policy makers, especially given the commitment of Indonesia to reducing greenhouse gas emissions as part of the reducing emissions from deforestation and forest degradation in developing countries initiative (REDD +). The improved spatio-temporal detail of forest change monitoring products will make it possible to target policies and projects in meeting this commitment. Accurate, annual forest cover loss maps will be integral to many REDD + objectives, including policy formulation, definition of baselines, detection

  12. The impact of the Nitrates Directive on nitrogen emissions from agriculture in the EU-27 during 2000-2008.

    PubMed

    Velthof, G L; Lesschen, J P; Webb, J; Pietrzak, S; Miatkowski, Z; Pinto, M; Kros, J; Oenema, O

    2014-01-15

    A series of environmental policies have been implemented in the European Union (EU) to decrease nitrogen (N) emissions from agriculture. The Nitrates Directive (ND) is one of the main policies; it aims to reduce nitrate leaching from agriculture through a number of measures. A study was carried out to quantify the effects of the ND in the EU-27 on the leaching and runoff of nitrate (NO3(-)) to groundwater and surface waters, and on the emissions of ammonia (NH3), nitrous oxide (N2O), nitrogen oxides (NO(x)) and dinitrogen (N2) to the atmosphere. We formulated a scenario with and a scenario without implementation of the ND. The model MITERRA-Europe was used to calculate N emissions on a regional level in the EU-27 for the period 2000-2008. The calculated total N loss from agriculture in the EU-27 was 13 Mton N in 2008, with 53% as N2, 22% as NO3, 21% as NH3, 3% as N2O, and 1% as NO(x). The N emissions and leaching in the EU-27 slightly decreased in the period 2000-2008. Total emissions in the EU in 2008 were smaller with implementation of the ND than without the ND, by 3% for NH3, 6% for N2O, 9% for NO(x), and 16% for N leaching and runoff in 2008. However, regional differences were large. The lower emissions with ND were mainly due to the lower N inputs by fertilizers and manures. In conclusion, implementation of the ND decreased both N leaching losses to ground and surface waters, and gaseous emissions to the atmosphere. It is expected that the ND will result in a further decrease in N emissions in EU-27 in the near future, because the implementation of the measures for the ND is expected to become more strict. Copyright © 2013 Elsevier B.V. All rights reserved.

  13. The PCDD/PCDF Dioxin releases in the climate of environment of Jordan in the period (2000-2008)

    NASA Astrophysics Data System (ADS)

    Al-Dabbas, Mohammed Awwad

    2010-04-01

    Many environment problems of the full using of several categories of processing include mining, heat generators, direct combustion of forest fires, cement production, power plant, transport, medical waste. Dioxin/furan releases from these categories are one of these environment problems. Possible lines of reducing the PCDD/PCDF (Polychlorinated dibenzo-para-dioxins/Polychlorinated dibenzofurans) releases from these categories are elucidated. The contribution of this paper is present the identification and estimation of the latest figure of dioxin/furan releases in the climate of environment of Jordan in the period 2000-2008 from the following categories (cement, aluminum, ceramic, medical waste, power plant, land fill, ferrous and non-ferrous metals, uncontrolled combustion process (biomass burning, waste burning, accidental fires in house, transport). These finding shows the sign of growth of estimated PCDD/PCDF releases from categories which did not calculated and followed after 2003. The result shows the highest PCDD/PCDF release from landfill fires (62.75 g TEQ/year), medical waste (8.8264 g TEQ/year), and transport (3.0145 g TEQ/year). Jordan seeks by next years, a reduction in total releases of dioxins and furans from sources resulting from human activity. This challenge will apply to the aggregate of releases to the air nationwide and of releases to the water within the Jordan area. Jordan should conduct air monitoring for dioxin in order to track fluctuations in atmospheric deposition levels.

  14. Trends in overweight and obesity in Danish children and adolescents: 2000-2008--exploring changes according to parental education.

    PubMed

    Matthiessen, Jeppe; Stockmarr, Anders; Biltoft-Jensen, Anja; Fagt, Sisse; Zhang, Hao; Groth, Margit Velsing

    2014-06-01

    To examine the hypotheses that an overall levelling off in the prevalence of overweight and obesity during the period 2000-2008 has occurred, and that increasing social inequality in overweight and obesity exists in a nationally representative sample of Danish children and adolescents. The population comprised a random sample of 1849 children aged 4-14 years who participated in the Danish National Survey of Diet and Physical Activity in 2000-2002, 2003-2004 and 2005-2008. Parental education was chosen as an indicator of children's socioeconomic status. Body mass index (BMI) was calculated from parent-reported weight and height. Subjects were classified as overweight and obese according to the International Obesity Task Force age- and gender-specific BMI cut-off values. Crude prevalence estimates and logistic regression models were used to analyse trends in overweight and obesity as the main outcome measures. An increase was found in the crude prevalence of overweight (including obesity) in boys (12.8-21.7%, p = 0.0006), but not in girls (17.6-15.9%, p = 0.56), between 2000-2002 and 2005-2008. The prevalence of overweight increased significantly in boys of parents with low educational level only. A strong inverse social gradient in overweight and obesity was documented for boys and girls during the whole survey period. The present study showed an increase in the prevalence of overweight in Danish boys, but not in girls. This increase was due to increasing social inequality in overweight among boys. Public health initiatives aimed at preventing and reducing overweight and obesity should consider gender difference and especially target boys with parents of low educational level. © 2014 the Nordic Societies of Public Health.

  15. Mentoring programs for medical students--a review of the PubMed literature 2000-2008.

    PubMed

    Frei, Esther; Stamm, Martina; Buddeberg-Fischer, Barbara

    2010-04-30

    Although mentoring is acknowledged as a key to successful and satisfying careers in medicine, formal mentoring programs for medical students are lacking in most countries. Within the framework of planning a mentoring program for medical students at Zurich University, an investigation was carried out into what types of programs exist, what the objectives pursued by such programs are, and what effects are reported. A PubMed literature search was conducted for 2000 - 2008 using the following keywords or their combinations: mentoring, mentoring program, medical student, mentor, mentee, protégé, mentorship. Although a total of 438 publications were identified, only 25 papers met the selection criteria for structured programs and student mentoring surveys. The mentoring programs reported in 14 papers aim to provide career counseling, develop professionalism, increase students' interest in research, and support them in their personal growth. There are both one-to-one and group mentorships, established in the first two years of medical school and continuing through graduation. The personal student-faculty relationship is important in that it helps students to feel that they are benefiting from individual advice and encourages them to give more thought to their career choices. Other benefits are an increase in research productivity and improved medical school performance in general. Mentored students also rate their overall well-being as higher. - The 11 surveys address the requirements for being an effective mentor as well as a successful mentee. A mentor should empower and encourage the mentee, be a role model, build a professional network, and assist in the mentee's personal development. A mentee should set agendas, follow through, accept criticism, and be able to assess performance and the benefits derived from the mentoring relationship. Mentoring is obviously an important career advancement tool for medical students. In Europe, more mentoring programs should be

  16. [Mortality trends from cervical cancer in the seven socioeconomic regions and the thirty two federative entities of Mexico, 2000-2008].

    PubMed

    Sánchez-Barriga, Juan Jesús

    2012-01-01

    To determinate the trend of mortality from cervical cancer nationwide, by federative entities and socioeconomic regions during the years 2000-2008. The records of mortality associated to cervical cancer for the period 2000-2008 were obtained from the National Information System of the Secretariat of Health. This information is generated by the National Institute of Statistics Geography and Informatics through the death certificates issued all around the country. The codes of the international disease classification 10 that correspond to the basic cause of death from cervical cancer were identified. The rates of mortality nationwide, by federative entity and by socioeconomic region were calculated. Through Poisson regression analysis was compared mortality rates from cervical cancer of the socioeconomic regions and federative entities. The 7 socioeconomic regions were elaborated by the National Institute of Statistics, Geography and Informatics and include the 32 federative entities according to indicators that are related to well-being such as education, occupation, health, housing and employment. The federative entities and socioeconomic region with the strongest association with mortality from cervical cancer in the period 2000-2008 were Colima (RR: 1.67, IC 95%: 1.11-2.25 for the year 2000; RR: 1.92, IC 95%: 1.29-2.85 for the year 2008); Veracruz (RR: 1.85,IC 95%: 1.51-2.27 for 2000; RR: 1.91, IC 95%: 1.55-2.35 for 2008); Yucatan (RR: 2.24, IC 95%: 1.74-2.88 for 2000; RR:1.90, IC 95%: 1.44-2.49 for 2008); and region 1 (RR: 1.41, IC 95%: 1.23-1.6 for 2001; RR: 1.38, IC 95%: 1.2-1.58 for 2007).In this region for the year 2000 and 2008 the RR was not statistically significant. Mortality rates per 100,000 women standardized using the world population decreased from 13.3 to 8.6 in the period 2000-2008. The entities and region with the strongest force of association with mortality due to cervical cancer were Colima, Veracruz,Yucatan and region 1.

  17. Modeling the Net Ecosystem Carbon Balance and Net Ecosystem Exchange of Agroecosystems of the Mid-Continent Intensive Campaign Region during 2000-2008

    NASA Astrophysics Data System (ADS)

    Izaurralde, R. C.; Zhang, X.; Post, W. M.; Thomson, A. M.; West, T. O.; Williams, J. R.; Manowitz, D.; Nichols, J.; Bandaru, V.; Doraiswamy, P. C.

    2009-12-01

    The terrestrial ecosystem model EPIC (Environment Policy Integrated Climate) is used to simulate the Net Ecosystem Carbon Balance (NECB) and Net Ecosystem Exchange (NEE) in the Mid-Continent Intensive Campaign Region during 2000-2008. EPIC simulates NECB as the difference between C additions (surface and subsurface litter, organic amendments) and C losses (harvest, heterotrophic respiration, soil erosion, and leaching), and NEE as the difference between net primary productivity and heterotrophic respiration. We used the USDA Crop Data Layer to delineate croplands and pasturelands, NCEP Reanalysis data to construct weather files, the SSURGO database to build soil layer files, the NRI database to build management files, and the CTIC database to capture the evolution of tillage practices during the study period. Each site is simulated multiple times by varying input parameters in order to estimate output uncertainty. Simulations of NECB and NEE are aggregated to and reported at the county scale in order to be compared with C flux results obtained using atmospheric inversion methods.

  18. Comparative morphology and morphometric assessment of the Neandertal occipital remains from the El Sidrón site (Asturias, Spain: years 2000-2008).

    PubMed

    Bastir, Markus; Rosas, Antonio; Tabernero, Antonio García; Peña-Melián, Angel; Estalrrich, Almudena; de la Rasilla, Marco; Fortea, Javier

    2010-01-01

    This paper analyses the occipital remains recovered from the El Sidrón (Asturias, Spain) Neandertal site between the years of 2000-2008. The sample is represented by three specimens, SD-1219, SD-1149, and SD-370a. Descriptive morphology, linear measurements, 3D geometric morphometrics, and virtual anthropological methods were employed to address the morphological, morphometric, and phylogenetic affinities of these fossils. The fossils display Neandertal autapomorphies (e.g., bilaterally protruding transverse occipital torus, suprainiac fossa). SD-1219 also preserves a strongly projecting juxtamastoid eminence and shows occipital bunning. In linear distances, the El Sidrón occipitals are similar to each other and close to the Neandertal mean. The centroid size of SD-1219 is slightly larger than the Neandertal average. All of the evidence taken together points to the hypothesis that SD-1219 belongs to a smaller Neandertal male. Linear measurements and the vault thickness of SD-1149 also suggest a robust male individual. The gracility of SD-370a points towards an immature individual. Virtual anthropological methods were used to reconstruct a 3D model of the SD-1219 occipital for geometric morphometrics, which reveals that SD-1219 shows relatively broad and low occipital plane proportions. Within the European Pleistocene lineage sample, this fossil falls geometrically closer to primitive rather than to derived morphologies because of its increased width, and a lower, anterior position of inion relative to the biasterionic axis. These results may imply that cranial sphericity could be an important feature of intraspecific Neandertal variability. Our findings open the way for further studies of intraspecific variation in Neandertal populations, in which the El Sidrón sample may play a significant role.

  19. Rates of obstetric intervention and associated perinatal mortality and morbidity among low-risk women giving birth in private and public hospitals in NSW (2000-2008): a linked data population-based cohort study.

    PubMed

    Dahlen, Hannah G; Tracy, Sally; Tracy, Mark; Bisits, Andrew; Brown, Chris; Thornton, Charlene

    2014-05-21

    To examine the rates of obstetric intervention and associated perinatal mortality and morbidity in the first 28 days among low-risk women giving birth in private and public hospitals in NSW (2000-2008). Linked data population-based retrospective cohort study involving five data sets. New South Wales, Australia. 691 738 women giving birth to a singleton baby during the period 2000-2008. Rates of neonatal resuscitation, perinatal mortality, neonatal admission following birth and readmission to hospital in the first 28 days of life in public and private obstetric units. Rates of obstetric intervention among low-risk women were higher in private hospitals, with primiparous women 20% less likely to have a normal vaginal birth compared to the public sector. Neonates born in private hospitals were more likely to be less than 40 weeks; more likely to have some form of resuscitation; less likely to have an Apgar <7 at 5 min. Neonates born in private hospitals to low-risk mothers were more likely to have a morbidity attached to the birth admission and to be readmitted to hospital in the first 28 days for birth trauma (5% vs 3.6%); hypoxia (1.7% vs 1.2%); jaundice (4.8% vs 3%); feeding difficulties (4% vs 2.4%) ; sleep/behavioural issues (0.2% vs 0.1%); respiratory conditions (1.2% vs 0.8%) and circumcision (5.6 vs 0.3%) but they were less likely to be admitted for prophylactic antibiotics (0.2% vs 0.6%) and for socioeconomic circumstances (0.1% vs 0.7%). Rates of perinatal mortality were not statistically different between the two groups. For low-risk women, care in a private hospital, which includes higher rates of intervention, appears to be associated with higher rates of morbidity seen in the neonate and no evidence of a reduction in perinatal mortality. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  20. Change in primary midwife-led care in the Netherlands in 2000-2008: a descriptive study of caesarean sections and other interventions among 789,795 low risk births.

    PubMed

    Offerhaus, Pien M; de Jonge, Ank; van der Pal-de Bruin, Karin M; Hukkelhoven, Chantal W P M; Scheepers, Peer L H; Lagro-Janssen, Antoine L M

    2014-05-01

    to study whether an increase in intrapartum referrals in primary midwife-led care births in the Netherlands is accompanied by an increase in caesarean sections. nationwide descriptive study. the Netherlands Perinatal Registry. 789,795 births of nine year cohorts of women with low risk pregnancies in primary midwife-led care at the onset of labour between 2000 and 2008. primary outcome is the caesarean section rate. Vaginal instrumental delivery, augmentation with oxytocin, and pharmacological pain relief are secondary outcomes. Trends in outcomes are described. We used logistic regression to explore whether changes in the planned place of birth and other maternal characteristics influenced the caesarean section rate. the caesarean section rate did not increase and was 5.5 per cent (range 4.9-6.3 per cent) for nulliparous women, and 1.0 per cent (range 0.8-1.1 per cent) for multiparous women. After controlling for the decline in planned home births and other maternal characteristics no increase in the caesarean section rate was found. The vaginal instrumental birth rate showed no increase, and was 18.1 per cent (range 17.9-18.5 per cent) for nulliparous women and 1.5 per cent (range 1.4-1.7 per cent) for multiparous women. Augmentation of labour and/or pharmacological pain relief increased from 24.0 to 38.8 per cent for nulliparous women, and from 5.4 to 10.0 per cent for multiparous women. the rise in intrapartum referrals was not accompanied by an increase in caesarean section rate over the period 2000-2008. Despite a considerable rise in the use of pain relief and augmentation, the rate of spontaneous vaginal birth remained high for low risk women who started labour in primary midwife-led care. the current strict role division between primary care midwives and the obstetrician-led team increasingly results in a change in care provider during labour. In a more integrated care system, more women can receive continuous support of labour from their own primary care

  1. Substance use and misuse in Brazilian movies (2000-2008).

    PubMed

    Castaldelli-Maia, João Mauricio; Bhugra, Dinesh; de Andrade, Arthur Guerra; Lotufo-Neto, Francisco

    2013-02-01

    Considering the absence of data on the appearance of drugs other than alcohol and tobacco in movie scenes, we decided to study the prevalence of portrayal of illicit drug use in a convenience sample of 50 Brazilian Movies. A total of 192 scenes (12h49'03(″)) meeting the inclusion criteria were identified and assessed in a structured manner. Despite several limitations regarding the nature of this comparison, we found that scenes show substance use and misuse almost similar to that in the general population, mainly alcohol (especially among people of low socioeconomic status), cannabis and inhalants. Main differences were found in cocaine and tranquilizers (over- and underexposure in movies, respectively).

  2. Bathymetric surveys of selected lakes in Missouri--2000-2008

    USGS Publications Warehouse

    Richards, Joseph M.

    2013-01-01

    Years of sediment accumulation and abnormally dry conditions in the Midwest in 1999 and 2000 led to the water level decline of many water-supply lakes in Missouri, and caused renewed interest in modernizing outdated area/volume tables for these lakes. The U.S. Geological Survey, in cooperation with the Missouri Department of Natural Resources and the U.S. Army Corps of Engineers, surveyed the bathymetry of 51 lakes in Missouri from July 2000 to May 2008. The data were used to provide water managers with area/volume tables and bathymetric maps of the lakes at the time of the surveys. In 50 of the lakes, bathymetric surveys were made using a boat-mounted single-beam survey-grade fathometer. In Clearwater Lake, bathymetric data were collected primarily using a boat-mounted survey-grade multibeam fathometer, and some bathymetric data were collected using a single-beam fathometer in areas of the lake that were inaccessible to the multibeam fathometer. Data processing, area/volume table computation, and bathymetric map production were completed for each lake.

  3. Phimosis in cats: 10 cases (2000-2008).

    PubMed

    May, Lauren R; Hauptman, Joe G

    2009-01-01

    Medical records of 10 cats diagnosed with phimosis were reviewed. The most common clinical signs exhibited were stranguria and pollakiuria, which occurred in eight out of 10 cats. The diagnosis of phimosis was made from physical examination alone in all cats. Eight of the 10 cats had surgical widening of the preputial orifice. Seven of these eight cats had follow-up of > or = 1 month, consisting of communications with the owner or referring veterinarian, who revealed resolution of preoperative clinical signs that were attributed to phimosis.

  4. Childhood cancer survival in France, 2000-2008.

    PubMed

    Lacour, Brigitte; Goujon, Stéphanie; Guissou, Sandra; Guyot-Goubin, Aurélie; Desmée, Solène; Désandes, Emmanuel; Clavel, Jacqueline

    2014-09-01

    This paper reports the latest survival data for French childhood cancer patients at the national level. Data from the two French National Registries of Childhood Cancer (Haematopoietic Malignancies and Solid Tumours) were used to describe survival outcomes for 15,479 children diagnosed with cancer between 2000 and 2008 in mainland France. The overall survival was 91.7% at 1 year, 86.9% at 2 years and 81.6% at 5 years. Relative survival did not differ from overall survival even for infants. Survival was lower among infants for lymphoblastic leukaemia and astrocytoma, but higher for neuroblastoma. For all cancers considered together, 5-year survival increased from 79.5% in the first (2000-2002) diagnostic period to 83.2% in the last (2006-2008) period. The improvement was significant for leukaemia, both myeloid and lymphoid, central nervous system tumours (ependymoma) and neuroblastoma. The results remained valid in the multivariate analysis, and, for all cancers combined, the risk of death decreased by 20% between 2000-2002 and 2006-2008. The figures are consistent with various international estimates and are the result of progress in treatment regimens and collaborative clinical trials. The challenge for the French registries is now to study the long-term follow-up of survivors to estimate the incidence of long-term morbidities and adverse effects of treatments.

  5. Cervical cancer in north-eastern Libya: 2000-2008.

    PubMed

    Ben Khaial, F; Bodalal, Z; Elramli, A; Elkhwsky, F; Eltaguri, A; Bendardaf, R

    2014-08-01

    Libya is a country with a low population, listed under the EMRO. Using registers and patient records from a major primary oncology clinic, data was gathered from Libyan cervical cancer patients and various parameters were studied across 9 years. Out of 4,090 female cancer cases during the study period, 1.8% were cervical cancer (n = 74). The average age of presentation was 53 years, with most of the cases (60%, n = 44) being premenopausal. Approximately 65% (n = 48) of cervical cancer patients are diagnosed at later stages (i.e. stages III and IV). The majority of these cases are squamous cell carcinoma (83.8%, n = 62), while 16.2% (n = 12) were found to be adenocarcinoma. Patients with squamous cell carcinoma presented at later stages more often than those with adenocarcinoma. Human papilloma virus was strongly implicated in cervical cancer, with 94% (n = 63) of those who were tested being positive for HPV-16 (82.5%, n = 52) and HPV-18 (12.7%, n = 8). Diagnosis was most frequently made through biopsy (97.3%, n = 72) as opposed to Pap smears (2.7%, n = 2). Most Libyan patients were put through chemotherapy (75%, n = 55) and triple therapy (surgery with combined chemotherapy and radiotherapy) was the most common (38%, n = 28) modality of treatment. Comparisons were made between Libya and other nations, either in the developed world or neighbouring countries. The major problem of cervical cancer in Libya is delayed presentation and hence, all the recommendations focus on increased awareness for the populace, implementation of a national cancer control plan and a national screening programme.

  6. Trachoma in Indigenous Settlements in Brazil, 2000-2008.

    PubMed

    Freitas, Helen Selma de Abreu; Medina, Norma Helen; Lopes, Maria de Fátima Costa; Soares, Oscar Espellete; Teodoro, Marco Túlio Costa; Ramalho, Karen Ruth Brock; Caligaris, Ligia Santos Abreu; Mörschbächer, Ricardo; de Menezes, Maria Nazaré Correia; Luna, Expedito José de Albuquerque

    2016-12-01

    Trachoma, caused by the bacterium Chlamydia trachomatis, is a chronic, recurrent inflammatory disease that affects the cornea and conjunctiva. Trachoma is the leading infectious cause of avoidable blindness worldwide. Its prevalence is higher among individuals of low socioeconomic status, and trachoma is common in indigenous communities. The present study presents aspects of the epidemiological profile of trachoma in indigenous communities in Brazil. We analyzed data from two databases collected during trachoma screening activities among the population of indigenous settlements in Brazil between 2000 and 2008. Trachoma cases were detected by ocular examination in accordance with the World Health Organization simplified trachoma grading system. According to the surveillance database, a total of 9582 individuals in six different states were examined. Among children aged 1-9 years, the prevalence of follicular trachomatous inflammation (TF) was 35.2%. In individuals aged ≥15 years, the prevalence of trachomatous trichiasis (TT) was 1.2% in individuals and the sex-specific prevalence was 0.8% in males and 1.6% in females (p = 0.02). In a survey of two states, 2301 indigenous schoolchildren were examined. In the age bracket 5-9 years, the prevalence of TF was 4.9 (95% confidence interval 3.8-6.0%). In Brazil, trachoma appears to be a serious public health problem in indigenous settlements, which should therefore be given priority in programs aimed at the elimination of trachoma in the country.

  7. Changes in national park visitation (2000-2008) and interest in outdoor activities (1993-2008)

    Treesearch

    Rodney B. Warnick; Michael A. Schuett; Walt Kuentzel; Thomas A. More

    2010-01-01

    This paper addresses Pergams and Zaradic's (2006) assertions that recent national park visitation has declined sharply and that these declines are directly related to the increased use of electronic media and passive forms of entertainment. We analyzed two large, national datasets that have used consistently replicated methods of annual data collection over a...

  8. Aetiology and epidemiology of human cryptosporidiosis cases in Galicia (NW Spain), 2000-2008.

    PubMed

    Abal-Fabeiro, J L; Maside, X; Llovo, J; Bartolomé, C

    2015-10-01

    Cryptosporidium infects millions of people worldwide causing acute gastroenteritis, but despite its remarkable epidemiological and economic impact, information on the epidemiological trends of human cryptosporidiosis is still scarce in most countries. Here we investigate a panel of 486 cases collected in Galicia (NW Iberian Peninsula) between 2000 and 2008, which sheds new light on the epidemiology in this region of the South Atlantic European façade. Incidence rates in Galicia are one order of magnitude higher than those reported in other regions of Spain, suggesting that this parasite remains largely underdiagnosed in this country, and are also larger than those typical of other European countries with available data. Two species dominate our dataset, Cryptosporidium hominis (65%) and C. parvum (34%). The sex ratio of patients infected by either species was 0·5, but C. hominis was significantly more common in younger males. C. parvum infections were more acute and required more specialized medical attention, which suggests a differential adaptation of each species to human hosts. The parasites display strong seasonal and geographical variation. C. parvum incidence peaked during summer and was mainly detected in rural areas while C. hominis infections were more frequent in autumn and exhibited a more even geographical distribution. Such differences probably reflect their distinct sources of infection - C. parvum is mainly zoonotic and C. hominis anthroponotic - and the effects of climatic variables, like temperature and rainfall.

  9. Marketing Activities and Usage in Historically Black College and University Libraries 2000-2008

    ERIC Educational Resources Information Center

    Walsh, Janet

    2012-01-01

    The academic library has experienced overall growth and decline based on demographics, technology, and convenience, yet several problems face academic libraries today including: (a) perceived relevance, (b) market share, and (c) competition. The purpose of this study was to explore marketing activities and library usage in HBCU libraries. The…

  10. Spaceborne and field-based observations of Bezymianny Volcano, Kamchatka from 2000- 2008

    NASA Astrophysics Data System (ADS)

    Carter, A.; Ramsey, M.; Girina, O.; Belousov, A.; Durant, A.; Skilling, I.; Wolfe, A.

    2008-12-01

    Bezymianny is a very active stratovolcano located on the Kamchatka Peninsula, Russia. It is andesitic in magma composition and typically erupts one to two times per year. The aim of this study was to ascertain background thermal conditions, attempt to locate any thermal precursory signals, and investigate the deposition and cooling of pyroclastic flow deposits that are typically emplaced on the south-eastern flank. Block and ash samples were collected and analyzed using Scanning Electron Microscope (SEM) images and thermal infrared (TIR) spectroscopy to estimate the surface vesicularity of the blocks and ash within the deposit. In addition, data from the March 2000, January 2005, December 2006, October 2007, and August 2008 explosive eruptions have been collected using the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) with limited field-based ground studies. According to the Kamchatkan Volcanic Eruption Response Team (KVERT) and the Alaska Volcano Observatory (AVO), another explosive eruption occurred at Bezymianny Volcano on 19 August 2008 around 10:30 UTC. A clear linear thermal anomaly was observed oriented to the southeast at the lava dome in rapid-response night time ASTER data acquired on 26 August. Preliminary results show that the maximum temperature recorded was 51.6 C (52 C above background). This likely corresponded to a short (1.3 km) lava lobe that was emplaced within a pre- existing channel. Further to the southeast, a significant thermal anomaly was observed with temperatures reaching 21 C within the centre of the anomaly, due to a warm pyroclastic flow (PF) that travelled 4.8 km from the summit. This work highlights the utility of TIR data in combination with field studies (where possible) over a highly changeable, active volcanic region and continues to stress the critical need for high spatial and temporal resolution data in Kamchatka specifically and in the North Pacific region in general.

  11. Children injured by violence in the United States: emergency department utilization, 2000-2008.

    PubMed

    Monuteaux, Michael C; Lee, Lois; Fleegler, Eric

    2012-05-01

    Children victimized by violence are often treated in the emergency department (ED). However, our understanding of the magnitude and financial costs of this patient population is inadequate. The authors examined the scope, risk factors for, and financial cost of ED visits for intentional injury in children in the United States over time. Using data from the National Hospital Ambulatory Medical Care Survey (NHAMCS) from 2000 through 2008, the records of children aged 0 to 17 years evaluated in an ED for intentional injuries were examined. Nationally representative rates of ED visits for intentional injuries, the proportion of ED visits accounted for by children with intentional injuries, and risk factors for intentional injury visits were calculated. The Web-based Injury Statistics Query and Reporting System (WISQARS) Cost of Injury Reports was used to generate the medical costs accrued by intentional injuries in children. Almost 340,000 children were treated in U.S. EDs each year from 2000 through 2008 for intentional injuries, comprising 1.2% (95% confidence interval [CI] = 1.1% to 1.4%) of all U.S. pediatric ED visits. The rate of ED visits for violent injuries has not changed over time. In 2008, 49 children per 10,000 (95% CI = 36 to 61) were treated in the ED for a violent injury. In a multivariate model, increasing age, residing in a metropolitan area, African American race, and the lack of private insurance were independent predictors of intentional injury visits among children. In 2005, the aggregate medical cost of intentionally inflicted injuries in children in the United States was $765 million. ED visits among children for violent injury still represent an important clinical, public health, and economic challenge. The ED could be considered as a potential venue for prevention and intervention efforts. © 2012 by the Society for Academic Emergency Medicine.

  12. Biopharmaceutical innovation system and the influence of policies:the case of taiwan (2000-2008).

    PubMed

    Chung, Chao Chen

    2013-08-01

    This article discusses the influence of policies on the development of biopharmaceuticals. We choose the experiences of Taiwan for our empirical study and focus on the evolution between 2000 and 2008; in the period of time the country provides an interesting example for further exploration of biopharmaceutical policies. Among all the policies, the two National Programs (National Research Program for Genetic Medicine and National Science and Technology Program for Biotechnology and Pharmaceuticals) and the Law of Pharmaceutical Affairs showed the contrasting effects on the innovation system of biopharmaceuticals. As a result, the government generated very limited positive influence on the innovation of biopharmaceuticals.

  13. Epidemiological characteristics of Brazilian spotted fever in Minas Gerais State, Brazil, 2000-2008.

    PubMed

    Amâncio, Frederico Figueiredo; Amorim, Vânia Dutra; Chamone, Talita Leal; Brito, Mariana Gontijo de; Calic, Simone Berger; Leite, Anamaria Cordeiro; Fraga, Gabriela Lobato; Ferraz, Marcela Lencine

    2011-10-01

    Brazilian spotted fever is the most common rickettsiosis in Brazil, most prevalent in the States of São Paulo and Minas Gerais. The aim of this study was to describe the epidemiological characteristics of Brazilian spotted fever in Minas Gerais from 2000 to 2008. Of the 132 cases of Brazilian spotted fever, 53 patients died, representing a case-fatality rate of 40.2%. Males predominated, with 78.8% of confirmed cases, and median age was 26.5 years. Absence of rash was associated with increased risk of death (p = 0.005). Greater Metropolitan Belo Horizonte, Rio Doce Valley, and Zona da Mata accounted for 70.6% of the cases, which occurred mainly from May to November. There was an increase in the number of cases, which could suggest an expansion of the disease, but probably resulted from an increase in the health system's diagnostic capacity and sensitivity. Despite this improvement, the case-fatality rate remains high and with no apparent tendency to decrease, thus indicating the need for improved prevention and patient care.

  14. Marketing Activities and Usage in Historically Black College and University Libraries 2000-2008

    ERIC Educational Resources Information Center

    Walsh, Janet

    2012-01-01

    The academic library has experienced overall growth and decline based on demographics, technology, and convenience, yet several problems face academic libraries today including: (a) perceived relevance, (b) market share, and (c) competition. The purpose of this study was to explore marketing activities and library usage in HBCU libraries. The…

  15. Botulism in Brazil, 2000-2008: epidemiology, clinical findings and laboratorial diagnosis.

    PubMed

    Rowlands, Ruth Estela Gravato; Ristori, Christiane Asturiano; Lopes, Giselle Ibette S Lopez; Paula, Ana Maria Ramalho de; Sakuma, Harumi; Grigaliunas, Raquel; Lopreato Filho, Roberto; Gelli, Dilma Scala; Eduardo, Maria Bernadete de Paula; Jakabi, Miyoko

    2010-01-01

    Botulism is a rare and potentially lethal illness caused by Clostridium botulinum neurotoxin. We describe the findings of a laboratorial investigation of 117 suspected cases of botulism reported to the surveillance system in Brazil from January 2000 to October 2008. Data on the number and type of samples analyzed, type of toxins identified, reporting of the number of botulism cases and transmission sources are discussed. A total of 193 clinical samples and 81 food samples were analyzed for detection and identification of the botulism neurotoxin. Among the clinical samples, 22 (11.4%) presented the toxin (nine type A, five type AB and eight with an unidentified type); in food samples, eight (9.9%) were positive for the toxin (five type A, one type AB and two with an unidentified type). Of the 38 cases of suspected botulism in Brazil, 27 were confirmed by a mouse bioassay. Laboratorial botulism diagnosis is an important procedure to elucidate cases, especially food-borne botulism, to confirm clinical diagnosis and to identify toxins in food, helping sanitary control measures.

  16. The Development of Small-Payload Rideshare Capabilities: A 2000-2008 Summary

    NASA Technical Reports Server (NTRS)

    Herrell, Linda M.; Peden, Josheph C.

    2008-01-01

    This paper summarizes the development from 200 to the present of rideshare capabilities by various Government agencies and Organizations. This development will allow acceptable, low cost access to space for small satellites and payloads. The paper reviews the needs for such capabilities and provides an overview of the development and status of the enabling technologies, hardware, etc. required to achieve the desired capability. It reviews the development and status of each principal element necessary in developing an acceptable, low cost, access to space capability for small satellites and payloads.

  17. Retention among North American HIV-infected persons in clinical care, 2000-2008.

    PubMed

    Rebeiro, Peter; Althoff, Keri N; Buchacz, Kate; Gill, John; Horberg, Michael; Krentz, Hartmut; Moore, Richard; Sterling, Timothy R; Brooks, John T; Gebo, Kelly A; Hogg, Robert; Klein, Marina; Martin, Jeffrey; Mugavero, Michael; Rourke, Sean; Silverberg, Michael J; Thorne, Jennifer; Gange, Stephen J

    2013-03-01

    Retention in care is key to improving HIV outcomes. The goal of this study was to describe 'churn' in patterns of entry, exit, and retention in HIV care in the United States and Canada. Adults contributing ≥1 CD4 count or HIV-1 RNA (HIV-lab) from 2000 to 2008 in North American AIDS Cohort Collaboration on Research and Design clinical cohorts were included. Incomplete retention was defined as lack of 2 HIV-laboratories (≥90 days apart) within 12 months, summarized by calendar year. Beta-binomial regression models were used to estimate adjusted odds ratios (OR) and 95% confidence intervals (CI) of factors associated with incomplete retention. Among 61,438 participants, 15,360 (25%) with incomplete retention significantly differed in univariate analyses (P < 0.001) from 46,078 (75%) consistently retained by age, race/ethnicity, HIV risk, CD4, antiretroviral therapy use, and country of care (United States vs. Canada). From 2000 to 2004, females (OR = 0.82, CI: 0.70 to 0.95), older individuals (OR = 0.78, CI: 0.74 to 0.83 per 10 years), and antiretroviral therapy users (OR = 0.61, CI: 0.54 to 0.68 vs. all others) were less likely to have incomplete retention, whereas black individuals (OR = 1.31, CI: 1.16 to 1.49, vs. white), those with injection drug use HIV risk (OR = 1.68, CI: 1.49 to 1.89, vs. noninjection drug use), and those in care longer (OR = 1.09, CI: 1.07 to 1.11 per year) were more likely to have incomplete retention. Results from 2005 to 2008 were similar. From 2000 to 2008, 75% of the North American AIDS Cohort Collaboration on Research and Design population was consistently retained in care with 25% experiencing some changes in status or churn. In addition to the programmatic and policy implications, the findings of this study identify patient groups who may benefit from focused retention efforts.

  18. Canine and feline epileptic seizures and the lunar cycle: 2,507 seizures (2000-2008).

    PubMed

    Browand-Stainback, Laura; Levesque, Donald; McBee, Matthew

    2011-01-01

    Epileptic seizures in 211 canine and feline patients diagnosed with idiopathic epilepsy were evaluated for temporal significance in relation to the lunar cycle. Seizure counts were compared among each of the eight individual lunar phases, among each of eight exact lunar phase dates, and by percent of lunar illumination using generalized estimating equations. No statistical significance was found in any of these comparisons excluding a relationship between the onset of epileptic seizures and the phases of the moon. Alteration in anticonvulsant treatment or monitoring of canine and feline patients with idiopathic epilepsy at large was not warranted based on the lunar cycle.

  19. Return to work following unilateral enucleation in 34 horses (2000-2008).

    PubMed

    Utter, M E; Wotman, K L; Covert, K R

    2010-03-01

    REASONS FOR STUDY: The effect of unilateral enucleation on vision and potential loss of performance in horses has received little study. To evaluate the likelihood of return to prior discipline following unilateral enucleation in horses, assessing the role of age at enucleation, equine discipline, reason for enucleation, time to vision loss and eye enucleated. Unilateral enucleation has no significant effect on likelihood of return to work in horses, for both right and left eyes, across age and discipline. A retrospective review of medical records identified 92 horses that underwent unilateral enucleation at the University of Pennsylvania New Bolton Center from April 2000-April 2008. Case variables determined from the medical record included breed and sex of horse, age at enucleation, which eye was enucleated, reason for enucleation and onset of vision loss. Pre- and post operative occupations were determined by telephone interview with the owner or trainer of each horse. Based on hospital surgery logs, 92 enucleations were performed over the 8 year period and 77 records were available for review, with follow-up information available for 34 horses. Of these, 29/34 (85%) horses returned to work in pleasure or trail riding (11/13), flat racing (7/10), hunter/jumpers (4/4), dressage (3/3), group lessons (1/1), eventing (1/1), steeplechase (1/1) and as a broodmare (1/1). Four of 5 horses (4/34, or 12% sample) that did not return to work (2 pleasure and 2 racing) were retired due to anticipated or perceived decrease in performance or behaviour change following unilateral enucleation, with the remaining horse retired from racing for lameness issues unrelated to enucleation. Twenty-two of 25 horses (88%) with acute vision loss and 7/9 horses (78%) with gradual vision loss returned to their previous discipline. Horses are able to return to a variety of occupations after unilateral enucleation.

  20. [Complaints by private health insurance policy-holders to the Consumer Protection Bureau in Argentina, 2000-2008].

    PubMed

    Luzuriaga, María José; Spinelli, Hugo

    2014-05-01

    This paper analyzes problems experienced by policy-holders of voluntary private health insurance plans in Argentina when insurance companies fail to comply with the Consumer Protection Code. The sample consisted of consumer complaints filed with the Consumer Protection Bureau and rulings by the Bureau from 2000 to 2008. One striking issue was recurrent non-compliance with services included in the Mandatory Medical Program and the companies' attempts to blame policy-holders. According to the study, the lack of an information system hinders scientific studies to adequately address the problem. Thus, a comparison with studies on health insurance in other Latin American countries highlighted the importance of such research, the relationship to health systems, constraints on use and denial of citizens' rights to healthcare, and the increasing judicialization of healthcare provision.

  1. Mortality and causes of death among incident cases of systemic lupus erythematosus in Finland 2000-2008.

    PubMed

    Elfving, P; Puolakka, K; Kautiainen, H; Virta, L J; Pohjolainen, T; Kaipiainen-Seppänen, O

    2014-11-01

    The objectives of the study were to investigate mortality and causes of death in patients with recent-onset systemic lupus erythematosus (SLE) in Finland. Data for patients with SLE for the study were collected (2000-2007) from the nationwide register on decisions of special reimbursements for drugs, maintained by the Social Insurance Institution (SII) in Finland. Data on deaths of the patients were obtained from the official death certificate statistics of Statistics Finland until the end of 2008. Of the 566 incident SLE patients, median follow-up time was 5.4 (IQR 3.3, 7.1) years, and 30 patients (23 females, seven males) died in the years 2000 through 2008. Mean age at death was 67.8 ± 17.2 years for females and 62.3 ± 15.2 years for males. The 5-year survival rates were 94.8% (95%CI 92.0-96.6%) and 88.2% (95%CI 76.5-94.3%), respectively. The age- and sex-adjusted standardized mortality ratio was 1.48 (95%CI 1.01-2.12). Primary causes of death were cardiovascular diseases, malignancy and SLE itself. In conclusion, survival of the patients with SLE was inferior to that of the general population. Cardiovascular diseases were responsible for 37% of deaths.

  2. International Space Station Science Research Accomplishments During the Assembly Years: An Analysis of Results from 2000-2008

    NASA Technical Reports Server (NTRS)

    Evans, Cynthia A.; Robinson, Julie A.; Tate-Brown, Judy; Thumm, Tracy; Crespo-Richey, Jessica; Baumann, David; Rhatigan, Jennifer

    2009-01-01

    This report summarizes research accomplishments on the International Space Station (ISS) through the first 15 Expeditions. When research programs for early Expeditions were established, five administrative organizations were executing research on ISS: bioastronautics research, fundamental space biology, physical science, space product development, and space flight. The Vision for Space Exploration led to changes in NASA's administrative structures, so we have grouped experiments topically by scientific themes human research for exploration, physical and biological sciences, technology development, observing the Earth, and educating and inspiring the next generation even when these do not correspond to the administrative structure at the time at which they were completed. The research organizations at the time at which the experiments flew are preserved in the appendix of this document. These investigations on the ISS have laid the groundwork for research planning for Expeditions to come. Humans performing scientific investigations on ISS serve as a model for the goals of future Exploration missions. The success of a wide variety of investigations is an important hallmark of early research on ISS. Of the investigations summarized here, some are completed with results released, some are completed with preliminary results, and some remain ongoing.

  3. Review of Recent Research (2000-2008) on Applied Linguistics and Language Teaching with Specific Reference to L2 Italian

    ERIC Educational Resources Information Center

    Macaro, Ernesto

    2010-01-01

    Italian has for many years been considered somewhat of a specialist language when studied as a second language (L2) and this is perhaps due to historical and cultural factors. Its footprint worldwide compared to such languages as English, Spanish and French is therefore somewhat limited. Surprisingly, however, there is a considerable body of…

  4. Health Policy and Systems Research in Twelve Eastern Mediterranean Countries: a stocktaking of production and gaps (2000-2008)

    PubMed Central

    2011-01-01

    Background The objectives of this study are to: (1) profile the production of Health Policy and Systems Research (HPSR) published between 2000 and 2008 in 12 countries in the Eastern Mediterranean Region (EMR): Bahrain, Egypt, Jordan, Lebanon, Libya, Morocco, Oman, Palestine, Sudan, Syria, Tunisia, and Yemen; (2) identify gaps; and (3) assess the extent to which existing HPSR produced in the region addresses regional priorities pertaining to Health Financing, Human Resources for Health and the Role of the Non-State Sector. This is the first stocktaking paper of HPSR production and gaps in the EMR. Methods Articles indexed on Medline between years 2000 and 2008 for the 12 study countries were selected. A MeSH term based search was conducted using country names. Articles were assessed using a coding sheet adapted for the region which included themes on: Governance Arrangements, Financial Arrangements, Delivery Arrangements, and Implementation Strategies. Identified articles were matched against regional research priorities to assess the extent to which research production aligns with priorities. Results A total of 1,487 articles (11.94%) fit the criteria in the coding sheet. Results showed an increase in HPSR production which peaked after 2005. Most identified articles focused on Delivery Arrangements (68.1%), and Implementation Strategies (24.4%). Most HPSR addressed priorities in Human Resources for Health (39%), and some articles focused on Health Financing (12%) and Role of the Non-State Sector (6.1%). Conclusions Despite global calls for producing and translating HPSR into policy, there are still significant gaps in the EMR. More efforts are needed to produce HPSR and align production and translation with the demand for evidence by policymakers. Findings can help inform and direct future plans and activities for the Evidence Informed Policy Network- EMR, World Health Organization- EMR, and the Middle East and North Africa Health Policy Forum, in addition to being useful for countries that host or are planning to host KT platforms in the region. PMID:21978482

  5. Research on the factors of return on equity: empirical analysis in Chinese port industries from 2000-2008

    NASA Astrophysics Data System (ADS)

    Li, Wei

    2011-12-01

    Port industries are the basic industries in the national economy. The industries have become the most modernized departments in every country. The development of the port industry is not only advantageous to promote the optimizing arrangement of social resources, but also to promote the growth of foreign trade volume through enhancing the transportation functions. Return on equity (ROE) is a direct indicator related to the maximization of company's wealth. It makes up the shortcomings of earnings per share (EPS). The aim of this paper is to prove the correlation between ROE and other financial indicators by choosing the listed port companies as the research objectives and selecting the data of these companies from 2000 to 2008 as empirical sample data with statistical analysis of the chartered figure and coefficient. The detailed analysis method used in the paper is the combination of trend analysis, comparative analysis and the ratio of the factor analysis method. This paper analyzes and compares all these factors and draws the conclusions as follows: Firstly, ROE has a positive correlation with total assets turnover, main profit margin and fixed asset ratio, while has a negative correlation with assets liabilities ratio, total assets growth rate and DOL. Secondly, main profit margin has the greatest positive effect on ROE among all these factors. The second greatest factor is total assets turnover, which shows the operation capacity is also an important indicator after the profitability. Thirdly, assets liabilities ratio has the greatest negative effect on ROE among all these factors.

  6. Research on the factors of return on equity: empirical analysis in Chinese port industries from 2000-2008

    NASA Astrophysics Data System (ADS)

    Li, Wei

    2012-01-01

    Port industries are the basic industries in the national economy. The industries have become the most modernized departments in every country. The development of the port industry is not only advantageous to promote the optimizing arrangement of social resources, but also to promote the growth of foreign trade volume through enhancing the transportation functions. Return on equity (ROE) is a direct indicator related to the maximization of company's wealth. It makes up the shortcomings of earnings per share (EPS). The aim of this paper is to prove the correlation between ROE and other financial indicators by choosing the listed port companies as the research objectives and selecting the data of these companies from 2000 to 2008 as empirical sample data with statistical analysis of the chartered figure and coefficient. The detailed analysis method used in the paper is the combination of trend analysis, comparative analysis and the ratio of the factor analysis method. This paper analyzes and compares all these factors and draws the conclusions as follows: Firstly, ROE has a positive correlation with total assets turnover, main profit margin and fixed asset ratio, while has a negative correlation with assets liabilities ratio, total assets growth rate and DOL. Secondly, main profit margin has the greatest positive effect on ROE among all these factors. The second greatest factor is total assets turnover, which shows the operation capacity is also an important indicator after the profitability. Thirdly, assets liabilities ratio has the greatest negative effect on ROE among all these factors.

  7. Human T-lymphotropic virus infections in active component service members, U.S. Armed Forces, 2000-2008.

    PubMed

    Petruccelli, Bruno P; Murray, Clinton K; Davis, Kenneth W; McBride, Richard; Peel, Sheila A; Michael, Nelson; Scott, Paul T; Hakre, Shilpa

    2014-02-01

    Emergency whole blood transfusions may increase the risk of transmitting bloodborne pathogens, including human T-lymphotropic viruses (HTLVs). U.S. military personnel with any medical encounter for HTLV infection during 2000-2013;2008 were identified from surveillance data. Using both inclusive and restrictive case definitions, the incidence of diagnoses of HTLV infection was analyzed in relation to demographic factors and prior deployment. There were 247 "possible" cases of HTLV infection identified, or 1.88 cases per 100,000 person-years (p-yrs) (95% CI 1.66, 2.13). Seventy of these met the restrictive definition, translating to a rate of 0.53 per 100,000 p-yrs (95% CI 0.42, 0.67). Under the restrictive definition, a higher rate was noted among females versus males (RR 2.37; 95% CI 1.41, 3.98), service members with a healthcare occupation versus those who are primarily trained to engage in combat (RR 2.54; 95% CI 1.06, 6.10), and service members with any deployment experience (RR 8.98; 95% CI 5.61, 14.37). These findings, and a prior military case report of transfusion-transmitted HTLV-I, suggest a need to better define the epidemiology of HTLV in U.S. military personnel to further ensure emergency transfusion safety.

  8. Practice patterns in the management of patients with differentiated thyroid cancer in Ontario Canada 2000-2008.

    PubMed

    Hall, Stephen F; Irish, Jonathan C; Groome, Patti A; Urbach, David R

    2014-07-24

    The extent of treatment for differentiated thyroid cancer remains controversial. The objective of this study was to describe the variations in practice prior to diagnosis and for the first year after diagnosis, including the investigations, the extent of surgery and the use of RAI 131, for all patients with thyroid cancer (TC) treated Jan 1 2000 to Dec 2008 across Ontario Canada. Population-based study of all patients who had a therapeutic surgical procedure for TC based on the data holdings of the Institute of Clinical Investigative Sciences (ICES) linking the Ontario Cancer Registry to the Ontario Health Insurance Plan and to the Canadian Institutes of Health Information. The analysis includes comparisons between health care utilization/geographic regions and between treating specialties. The study population was 12957 patients. There was a 112% increase in case detection over 9 years. Overall the initial (index) surgery was less-than-total thyroidectomy (LTT) in 37.6% and 63.4% of the patients who had total thyroidectomy (TT) as an index surgery went on to adjuvant RAI, however there was wide variation in all aspects of patient care across the province, between Local Health Networks and between surgical specialties. In Ontario, there was wide variation for most aspects of the management of TC and, as the incidence of TC is increasing at least 7% per year in females, these data provide a foundation for future discussions, the provision of health care services and research.

  9. The Unchanging American Capacity in Languages Other than English: Speaking and Learning Languages Other than English, 2000-2008

    ERIC Educational Resources Information Center

    Rivers, William P.; Robinson, John P.

    2012-01-01

    We present results of 2006 and 2008 replications of the 2000 General Social Survey (GSS), which included nine questions on languages other than English (LOEs) spoken (Robinson, Rivers, & Brecht, 2006). In 2000, 26% claimed they could speak another language, with 10% saying they could speak it "very well." In 2000, foreign language…

  10. The Unchanging American Capacity in Languages Other than English: Speaking and Learning Languages Other than English, 2000-2008

    ERIC Educational Resources Information Center

    Rivers, William P.; Robinson, John P.

    2012-01-01

    We present results of 2006 and 2008 replications of the 2000 General Social Survey (GSS), which included nine questions on languages other than English (LOEs) spoken (Robinson, Rivers, & Brecht, 2006). In 2000, 26% claimed they could speak another language, with 10% saying they could speak it "very well." In 2000, foreign language…

  11. [Evaluation of the tuberculosis program in Sapucaia do Sul, state of Rio Grande do Sul: indicators, 2000-2008].

    PubMed

    Heck, Maria Antonia; Costa, Juvenal Soares Dias da; Nunes, Marcelo Felipe

    2013-02-01

    The scope of this study was to describe the trends of tuberculosis indicators in relation to their prevalence, incidence and the case outcome percentages (cure, abandonment of treatment or death) for the patients who entered in the Program in Sapucaia do Sul, state of Rio Grande do Sul, between 2000 and 2008. An ecological analysis of the incidence was conducted and the gross frequency rates and respective confidence intervals of 95% were presented. The rate estimates were verified by means of average annual percent change as well as the mobile averages every three years. The prevalence rate was 64.3 and the incidence rate was 58.0 per 100.000 inhabitants. Analysis of the indicators did not reveal statistically significant differences between the annual rates or in the mobile averages during the period. The outcomes were below the targets proposed by the World Health Organization, what compromises control of the disease, as it is not proving possible to interrupt the chain of transmission.

  12. Risk factors for diarrhea hospitalization in Bangladesh, 2000-2008: a case-case study of cholera and shigellosis.

    PubMed

    Colombara, Danny V; Faruque, Abu S G; Cowgill, Karen D; Mayer, Jonathan D

    2014-08-15

    Cholera and shigellosis are endemic on the Indian subcontinent. Our objective was to identify cholera-specific risk factors distinct from shigellosis risk factors. We conducted a case-case study among hospitalized diarrheal patients, comparing those with cholera and shigellosis in International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b) hospitals in Matlab (rural) and Dhaka (urban) between January 1, 2000 and December 31, 2008. Multivariable Poisson regression models revealed that having more than nine years of education, compared to no education, was associated with a 39% (adjusted Risk Ratio [aRR] = 0.61, 95% confidence interval [CI]: 0.40-0.93) decreased risk for cholera hospitalization in Matlab and a 16% (aRR = 0.84, 95% CI: 0.75-0.94) decreased risk in Dhaka. Having a family member with diarrhea in the past seven days increased cholera hospitalization risk by 17% (aRR = 1.17, 95% CI: 1.09-1.26) in Matlab. Further studies are needed to elucidate the pathway through which education impacts cholera risk in order to create targeted interventions in cholera-endemic areas. Interventions seeking to reduce transmission and facilitate hygienic practices among family members of index cases with diarrhea should be considered, especially in rural cholera endemic settings.

  13. Effectiveness of OSHA Outreach Training on carpenters' work-related injury rates, Washington State 2000-2008.

    PubMed

    Schoenfisch, Ashley L; Lipscomb, Hester; Sinyai, Clayton; Adams, Darrin

    2017-01-01

    Despite the size and breadth of OSHA's Outreach Training program for construction, information on its impact on work-related injury rates is limited. In a 9-year dynamic cohort of 17,106 union carpenters in Washington State, the effectiveness of OSHA Outreach Training on workers' compensation claims rate was explored. Injury rates were calculated by training status overall and by carpenters' demographic and work characteristics using Poisson regression. OSHA Outreach Training resulted in a 13% non-significant reduction in injury claims rates overall. The protective effect was more pronounced for carpenters in their apprenticeship years, drywall installers, and with increasing time since training. In line with these observed effects and prior research, it is unrealistic to expect OSHA Outreach Training alone to have large effects on union construction workers' injury rates. Standard construction industry practice should include hazard awareness and protection training, coupled with more efficient approaches to injury control. Am. J. Ind. Med. 60:45-57, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  14. [Tuberculosis treatment drop out prevalence and associated factors in Sapucaia do Sul County (RS), Brazil, 2000-2008].

    PubMed

    Heck, Maria Antonia; da Costa, Juvenal Soares Dias; Nunes, Marcelo Felipe

    2011-09-01

    To estimate the Tuberculosis treatment drop out prevalence and the variables associated in the patients registered in the Tuberculosis Control Program in Sapucaia do Sul (Brazil), between 2000 and 2008. A cross-sectional study was conducted, which was based on the notified data in Information System for Disease Surveillance of the City Health Secretariat. From the 632 cases included in the study, 65 (10.3%; CI95%=7.9-12.7) were classified as treatment abandonment. Between 2000 and 2004, the prevalence of noncompliance was 12.7% (95%CI=9.1-16.2), and in the period 2005 to 2008 decreased to 7.0% (95%CI=4.0-9.9). In the crude analysis, we find association with sex, age and AIDS presence. The adjusted analysis with the Poisson regression didn't show significant differences between the independent variables. The analysis showed reduction in the prevalence of noncompliance with the creation of Tuberculosis Control Program, from 2005, although the confidence intervals are shown superimposed. Still, the prevalence of noncompliance was high and stove above the 5% target, agreed between levels of government.

  15. Reformatted data sets used in the Cooperative LACSD/USGS Palos Verdes Flow Study, 2000--2008

    USGS Publications Warehouse

    Anderson, Todd; Rosenberger, Kurt J.; Gartner, Anne L.

    2012-01-01

    Beginning in 1997, the Environmental Protection Agency (EPA) defined a contaminated section of the Palos Verdes shelf in southern California as a Superfund site, initiating a continuing investigation of this area. A number of agencies, including the EPA, U.S. Geological Survey (USGS), and Science Applications International Corporation (SAIC), conducted two oceanographic measurement programs in 2004 and 2007-2008 (SAIC, 2004, 2005; Rosenberger and others, 2010; Sherwood and others, unpublished data) to improve our understanding of the natural processes that resuspend and transport sediment in the area, especially in the region southeast of the Whites Point ocean outfall where earlier measurements were thought to be deficient. Los Angeles County Sanitation Districts (LACSD) deployed a simpler but much broader array of instruments on the Palos Verdes shelf and within the northern reaches of San Pedro Bay from 2000 to 2008 in order to characterize the current and temperature patterns within these regions. This program overlapped the two programs run by USGS and other agencies in 2004 and 2007. The LACSD data were made available to the USGS and the EPA in order to support their joint efforts to model the transport of the contaminated sediments in the region. This report describes the LACSD data sets, the instruments and data-processing procedures used, and the archive that contains the data sets that have passed our quality-assurance procedures.

  16. Half Empty or Half Full? Staffing Trends in Academic Libraries at U.S. Research Universities, 2000-2008

    ERIC Educational Resources Information Center

    Stewart, Christopher

    2010-01-01

    This study is a quantitative analysis of FTE staffing levels at academic libraries at 176 U.S. research universities between 2000 and 2008. Results showed that overall staffing levels at these libraries declined but that the average number of professional librarian FTE positions modestly increased. Other professional staff positions increased at a…

  17. Confieso que Divulgo. Reflexiones y Experiencias de una Astrofísica

    NASA Astrophysics Data System (ADS)

    Rodríguez Hidalgo, I.

    Este artículo presenta algunas reflexiones en torno a la popularización de la Ciencia, desarrolladas a lo largo de mi trayectoria profesional, un camino inacabado desde la intuición al oficio. Tras revisar las señas de identidad de la divulgación científica, se exponen ideas, experiencias y recursos, cribados por la práctica y su posterior análisis crítico. Se destacan las actividades relacionadas con la Astronomía, que se cuentan entre las más espectaculares y gratificantes. Confessions of a popularizer: This paper presents some author's thoughts about scientific outreach, developed along her professional path, an unfinished way from intuition to trade. First, identity signs of outreach are revised; then, ideas, experiences and resources, sifted by practice and further critical analysis, are reviewed. Activities related to Astronomy, being one of the most spectacular and rewarding, are remarked 1

  18. Resource Endowments and Responses to Regulatory Pressure: Publications of Economics, Management, and Political Science Departments of Turkish Universities in Indexed Journals, 2000-2008

    ERIC Educational Resources Information Center

    Onder, Cetin; Kasapoglu-Onder, Rana

    2011-01-01

    This paper investigates how differences in resource endowments of universities shape variation in their response to regulatory pressures. Earlier research on higher education institutions tends to conceive regulatory rules as the primary basis of action and does not attend to differences in the salient characteristics of universities. This paper…

  19. Scientific advancement of novel protein allergenicity evaluation: an overview of work from the HESI Protein Allergenicity Technical Committee (2000-2008).

    PubMed

    Thomas, Karluss; MacIntosh, Sue; Bannon, Gary; Herouet-Guicheney, Corinne; Holsapple, Michael; Ladics, Gregory; McClain, Scott; Vieths, Stefan; Woolhiser, Michael; Privalle, Laura

    2009-06-01

    The safety assessment of genetically modified crops includes the evaluation for potential allergenicity. The current 'state-of-the-science' utilizes a weight of evidence approach, as outlined by the Codex Alimentarius commission (Alinorm 03/34 A), recognizing no single endpoint is predictive of the allergenic potential of a novel protein. This approach evaluates: whether the gene source is allergenic, sequence similarity to known allergens, and protein resistance to pepsin in vitro. If concerns are identified, serological studies may be necessary to determine if a protein has IgE binding similar to known allergens. Since there was a lack of standardized/validated methods to conduct the allergenicity assessment, a committee was assembled under the International Life Sciences Institute Health and Environmental Sciences Institute to address this issue. Over the last eight years, the Protein Allergenicity Technical Committee has convened workshops and symposia with allergy experts and government authorities to refine methods that underpin the assessment for potential protein allergenicity. This publication outlines this ongoing effort, summarizing workshops and formal meetings, referencing publications, and highlighting outreach activities. The purpose is to (1) outline 'the state-of-the-science' in predicting protein allergenicity in the context of current international recommendations for novel protein safety assessment, and (2) identify approaches that can be improved and future research needs.

  20. Evaluation of carbon fluxes and trends (2000-2008) in the Greater Platte River Basin: a sustainability study on the potential biofuel feedstock development

    USGS Publications Warehouse

    Gu, Yingxin; Wylie, Bruce K.; Zhang, Li; Gilmanov, Tagir G.

    2012-01-01

    This study evaluates the carbon fluxes and trends and examines the environmental sustainability (e.g., carbon budget, source or sink) of the potential biofuel feedstock sites identified in the Greater Platte River Basin (GPRB). A 9-year (2000–2008) time series of net ecosystem production (NEP), a measure of net carbon absorption or emission by ecosystems, was used to assess the historical trends and budgets of carbon flux for grasslands in the GPRB. The spatially averaged annual NEP (ANEP) for grassland areas that are possibly suitable for biofuel expansion (productive grasslands) was 71–169 g C m−2 year−1 during 2000–2008, indicating a carbon sink (more carbon is absorbed than released) in these areas. The spatially averaged ANEP for areas not suitable for biofuel feedstock development (less productive or degraded grasslands) was −47 to 69 g C m−2 year−1 during 2000–2008, showing a weak carbon source or a weak carbon sink (carbon emitted is nearly equal to carbon absorbed). The 9-year pre-harvest cumulative ANEP was 1166 g C m−2 for the suitable areas (a strong carbon sink) and 200 g C m−2 for the non-suitable areas (a weak carbon sink). Results demonstrate and confirm that our method of dynamic modeling of ecosystem performance can successfully identify areas desirable and sustainable for future biofuel feedstock development. This study provides useful information for land managers and decision makers to make optimal land use decisions regarding biofuel feedstock development and sustainability.

  1. Detection of non-polio enteroviruses in Hungary 2000-2008 and molecular epidemiology of enterovirus 71, coxsackievirus A16, and echovirus 30.

    PubMed

    Kapusinszky, Beatrix; Szomor, Katalin N; Farkas, Agnes; Takács, Mária; Berencsi, György

    2010-04-01

    Human enteroviruses are associated with various clinical syndromes from minor febrile illness to severe, potentially fatal conditions like aseptic meningitis, paralysis, myocarditis, and neonatal enteroviral sepsis. Between June 2000 and August 2008 echovirus (E) type 2, 4, 6, 7, 9, 11, 13, 25, 30, coxsackievirus (CV) -A16, -A19, -B5, and enterovirus 71 (EV71) were reported in Hungary. In this study, 29 previously enterovirus positive samples from 28 patients diagnosed with hand, foot and mouth disease, meningitis and encephalitis, were molecularly typed. The genetic relationships of identified serotypes CV-A16, EV71, and E30 were assessed by direct sequencing of genomic region encoding the capsid protein VP1. The sequences were compared to each other and sequences from other geographical regions possessed in Genbank. The phylogenetic analysis of CV-A16 revealed that the viruses were mostly of Far-Eastern or Asia-Pacific origin. Typing of EV71 showed that one virus from 2000 belonged to genotype C1 and five viruses observed in 2004 and 2005 were identified as genotype C4. The 11 echovirus 30 strains showed homology with those of neighbor European countries. The molecular examination of E30 revealed that three separate lineages circulated in 2000, 2001, and 2004-2006 in Hungary.

  2. Translating knowledge into policy and action to promote health equity: The Health Equity Fund policy process in Cambodia 2000-2008.

    PubMed

    Ir, Por; Bigdeli, Maryam; Meessen, Bruno; Van Damme, Wim

    2010-08-01

    To understand how knowledge is used to inform policy on Health Equity Funds (HEFs) in Cambodia; and to draw lessons for translating knowledge into health policies that promote equity. We used a knowledge translation framework to analyse the HEF policy process between 2000 and 2008. The analysis was based on data from document analysis, key informant interviews and authors' observations. The HEF policy-making process in Cambodia was both innovative and incremental. Insights from pilot projects were gradually translated into national health policy. The uptake of HEF in health policy was determined by three important factors: a policy context conducive to the creation, dissemination and adoption of lessons gained in HEF pilots; the credibility and timeliness of HEF knowledge generated from pilot projects; and strong commitment, relationships and networks among actors. Knowledge locally generated through pilot projects is crucial for innovative health policy. It can help adapt blueprints and best practices to a local context and creates ownership. While international organisations and donors can take a leading role in innovative interventions in low-income countries, the involvement of government policy makers is necessary for their scaling-up. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.

  3. A Review of Recent Research (2000-2008) on Applied Linguistics and Language Teaching with Specific Reference to L2 Spanish

    ERIC Educational Resources Information Center

    Anton, Marta

    2011-01-01

    This review presents a broad picture of recent work on L2 Spanish in educational contexts. The thematic and geographic scope of the review is wide, in order to capture the diversity of learners and learning contexts of L2 Spanish, just two decades after teaching and learning the language gained impetus worldwide. Traditional second or foreign…

  4. Risk factors for severe cholera among children under five in rural and urban Bangladesh, 2000-2008: a hospital-based surveillance study.

    PubMed

    Colombara, Danny V; Cowgill, Karen D; Faruque, Abu S G

    2013-01-01

    Children under five bear the largest cholera burden. We therefore sought to identify modifiable risk factors among Bangladeshi children. We used multivariate Poisson regression to assess risk factors for severe cholera among diarrheal patients presenting at hospitals in Matlab (rural) and Dhaka (urban), Bangladesh. Risk increased with age. Compared to those under one, rural and urban four-year-olds had adjusted risk ratios (aRR) of 4.17 (95% confidence interval (CI) 2.43-7.15) and 6.32 (95% CI: 4.63-8.63), respectively. Breastfeeding halved the risk in both rural (aRR = 0.49, 95% CI: 0.35-0.67) and urban (aRR = 0.51, 95% CI: 0.41-0.62) settings. Rural children's risk decreased with maternal education (P-trend: <0.001) and increased among those with a family member with diarrhea in the past week (aRR = 1.61, 95% CI: 1.22-2.14) and those with prior vitamin A supplementation (aRR = 1.65, 95% CI: 1.12-2.43). Urban children whose mothers daily (aRR = 0.41, 95% CI: 0.21-0.79) or occasionally (aRR = 0.55, 95% CI: 0.36-0.84) read a newspaper experienced reduced risk. Urban children from households with incomes between 34-84 USD/month had a 30% increased risk compared to those from households with incomes >84 USD/month. Increasing age, lower socioeconomic status, and lack of breastfeeding are key correlates of increased risk for cholera hospitalization among those under five in rural and urban Bangladesh. In addition, having a family member with diarrhea in the past week was associated with increased risk among rural children. Continued attention should be directed to the promotion of breastfeeding. Further research is needed to elucidate the relationship between maternal education and cholera risk. Renewed research regarding the use of chemoprophylaxis among family members of cholera cases may be warranted in rural endemic settings.

  5. Resource Endowments and Responses to Regulatory Pressure: Publications of Economics, Management, and Political Science Departments of Turkish Universities in Indexed Journals, 2000-2008

    ERIC Educational Resources Information Center

    Onder, Cetin; Kasapoglu-Onder, Rana

    2011-01-01

    This paper investigates how differences in resource endowments of universities shape variation in their response to regulatory pressures. Earlier research on higher education institutions tends to conceive regulatory rules as the primary basis of action and does not attend to differences in the salient characteristics of universities. This paper…

  6. FACTORES SOCIO-ESTRUCTURALES Y EL ESTIGMA HACIA EL VIH/SIDA: EXPERIENCIAS DE PUERTORRIQUEÑOS/AS CON VIH/SIDA AL ACCEDER SERVICIOS DE SALUD

    PubMed Central

    RIVERA-DIAZ, MARINILDA; VARAS-DIAZ, NELSON; REYES-ESTRADA, MARCOS; SURO, BEATRIZ; CORIANO, DORALIS

    2013-01-01

    RESUMEN El estigma relacionado al VIH/SIDA continúa afectando la prestación de servicios de salud y el bienestar físico y mental de las personas con VIH/SIDA (PVS). Recientemente la literatura científica ha señalado la importancia de comprender las manifestaciones de estigma más allá de las interacciones individuales. Por tal razón, investigaciones recientes en y fuera de Puerto Rico enfatizan la importancia de entender cómo factores socio-estructurales (FSE) influyen en los procesos de estigmatización social. Con el propósito de examinar los FSE que influyen en las manifestaciones de estigma relacionado al VIH/SIDA, realizamos y analizamos nueve grupos focales compuestos por hombres y mujeres en tratamiento para el VIH/SIDA que habían tenido experiencias estigmatizantes. Los participantes identificaron FSE relacionados a las manifestaciones de estigma, tales como el uso de viviendas especializadas, descentralización de los servicios de salud y el desarrollo de protocolos administrativos excluyentes en los servicios de salud. Los resultados demuestran la importancia de considerar los FSE en el desarrollo e implementación de intervenciones dirigidas a la población. PMID:24639599

  7. [Treatment of syringomyelia in patients with Chiari malformation and craniosynostosis. A case report and review of the literature].

    PubMed

    Aransay-Garcia, A; Villarejo-Ortega, F J

    2016-11-16

    Introduccion. Los pacientes con craneosinostosis complejas o unisuturales presentan frecuentemente malformacion de Chiari y siringomielia. El tratamiento quirurgico de la siringomielia en estos pacientes es controvertido. Caso clinico. Niña de 3 años con craneosinostosis compleja no corregida quirurgicamente. Permanecio asintomatica a pesar de que en la resonancia magnetica craneal se evidencio una malformacion de Chiari y un año despues desarrollo una siringomielia cervicodorsolumbar. Se le realizo una craniectomia suboccipital descompresiva, pero posteriormente sufrio un empeoramiento de la siringomielia. El registro de presion intracraneal resulto patologico, por lo que se decidio realizar una craneotomia descompresiva frontoparietotemporal bilateral y remodelacion de la boveda craneal, con lo que se consiguio una disminucion significativa de la siringomielia. Conclusiones. Tras la revision de la bibliografia, se observa que actualmente no existe un consenso sobre el tratamiento de la siringomielia en los pacientes con craneosinostosis y malformacion de Chiari. Algunos autores recomiendan la simultanea descompresion quirurgica suboccipital y de la boveda craneal, otros solo la descompresion de la boveda craneal, y otros la ampliacion de la fosa posterior con distractores. En los casos en los que se realizo primero la descompresion suboccipital no se consiguio resolver ni estabilizar la siringomielia. Concluimos que el tratamiento mas eficaz para los pacientes con siringomielia y craneosinostosis es la remodelacion descompresiva de la boveda craneal, ya que el principal factor causante de la siringomielia es la hipertension intracraneal y la falta de distensibilidad del craneo.

  8. Response to injection of the navicular bursa with corticosteroid and hyaluronan following high-field magnetic resonance imaging in horses with signs of navicular syndrome: 101 cases (2000-2008).

    PubMed

    Marsh, Chad A; Schneider, Robert K; Sampson, Sarah N; Roberts, Greg D

    2012-11-15

    To determine treatment outcome on the basis of pathological changes identified on MRI and lameness duration in horses with navicular syndrome that underwent injection of corticosteroid and hyaluronan into the navicular bursa. Retrospective case series. 101 horses with navicular syndrome. Medical records of horses with signs of navicular syndrome evaluated between January 2000 and December 2008 were reviewed. Data on signalment, use of the horse, history, affected limbs, duration of lameness, findings on lameness examination, radiographic findings, MRI findings, treatment, and outcome were collected from the medical records. Follow-up information was obtained a minimum of 10 months after navicular bursa injection. Following navicular bursa injection, 76 of 101 (75%) horses returned to their intended use for a mean of 9.66 months, and 35 (35%) were sound at follow-up. Horses that had been lame for < 6 months before treatment were significantly more likely to return to their intended use, have a longer positive response to treatment, and be sound at follow-up, compared with horses that had a longer lameness history. Horses with primary deep digital flexor (DDF) tendonitis responded best to navicular bursa injection with rest and rehabilitation, followed by horses with navicular bursitis and horses with DDF tendonitis and adhesions to the collateral sesamoidean ligament of the distal sesamoid (navicular) bone. Horses with scar tissue in the proximal portion of the navicular bursa, adhesions from the navicular bone to the DDF tendon, or multiple abnormalities did not respond as well to treatment. Response to navicular bursa injection with corticosteroid and hyaluronan in horses with navicular syndrome was dependent on the disease process detected on MRI and duration of lameness.

  9. Experiencias sobre el impacto del Programa de Formación en Ética de la Investigación Biomédica y Psicosocial en el ámbito de la salud mental y la investigación conductual.

    PubMed

    Barrios, Liliana Mondragón

    2012-01-01

    El propósito de este trabajo es presentar el impacto y la integración que los conocimientos adquiridos en el Programa Internacional de Formación en Ética de la Investigación Biomédica y Psicosocial de la Universidad de Chile han tenido en mi experiencia profesional, en el ámbito de la investigación psicosocial en un Instituto de Salud de México. Para este objetivo, expondré tres áreas en las cuales se ha podido evidenciar tal impacto: trabajo en los comités de ética, desarrollo de programas de académicos en bioética e investigación y publicación sobre ética y bioética. El motivo que me llevó a incursionar en el Programa fue que su enseñanza vincula la investigación psicosocial con la ética y la bioética, lo cual me permitió dirigir este tipo de reflexión hacia problemas como violencia, suicidio, adicciones, depresión y salud mental, y a nuevos campos como los estudios comunitarios, con poblaciones en riesgo o vulnerables, en los cuales las diversas implicaciones son difíciles de indagar.

  10. Experiencias sobre el impacto del Programa de Formación en Ética de la Investigación Biomédica y Psicosocial en el ámbito de la salud mental y la investigación conductual

    PubMed Central

    Barrios, Liliana Mondragón

    2012-01-01

    El propósito de este trabajo es presentar el impacto y la integración que los conocimientos adquiridos en el Programa Internacional de Formación en Ética de la Investigación Biomédica y Psicosocial de la Universidad de Chile han tenido en mi experiencia profesional, en el ámbito de la investigación psicosocial en un Instituto de Salud de México. Para este objetivo, expondré tres áreas en las cuales se ha podido evidenciar tal impacto: trabajo en los comités de ética, desarrollo de programas de académicos en bioética e investigación y publicación sobre ética y bioética. El motivo que me llevó a incursionar en el Programa fue que su enseñanza vincula la investigación psicosocial con la ética y la bioética, lo cual me permitió dirigir este tipo de reflexión hacia problemas como violencia, suicidio, adicciones, depresión y salud mental, y a nuevos campos como los estudios comunitarios, con poblaciones en riesgo o vulnerables, en los cuales las diversas implicaciones son difíciles de indagar. PMID:22754085

  11. La Experiencia Mexicana (The Mexican Experience). Volumes I and II.

    ERIC Educational Resources Information Center

    Finer, Neal B.

    Designed to be used as part of a comprehensive social studies program on Mexican culture, this two-volume manual, written in Spanish, offers an instructional package on Mexican culture, stressing an art-architecture perspective, which can be used at the secondary, college and adult levels. The teacher's guide, Volume I, includes a discussion of a…

  12. Adult Latino College Students: Experiencias y la Educacion

    ERIC Educational Resources Information Center

    Garza, Ana Lisa

    2011-01-01

    The study aimed to gain a better understanding of the learning experiences of adult Latino college students, as described directly in their own voices. The study was guided by two research questions: RQ1: "How do adult Latinos describe their undergraduate college learning experiences?" and RQ2: "How do culture, gender, and ethnic…

  13. Nuestros Sentimientos Son Iguales, La Diferencia Es En La Experiencia

    ERIC Educational Resources Information Center

    Palomares, Uvaldo H.

    1971-01-01

    The author concludes that counselors may be the prime cause of miscommunication and prejudicial evaluation in relations with persons from divergent racial and ethnic groups. Counselors must recognize and value the ethnicity of other persons if they are to foster an open, trusting, and productive counseling relationship with them. (Author/BY)

  14. Expresiones de Desarrollo Profesional en Educadoras Principiantes y con Experiencia.

    ERIC Educational Resources Information Center

    Betsalel-Presser, Raquel

    1986-01-01

    Attempts to identify the conditions which affect the professional development of both experienced and inexperienced teachers. After presenting the theoretical and conceptual framework of the problem, discusses professional development needs identified by preschool and primary school teachers in an exploratory study done in Montreal, Quebec…

  15. Adult Latino College Students: Experiencias y la Educacion

    ERIC Educational Resources Information Center

    Garza, Ana Lisa

    2011-01-01

    The study aimed to gain a better understanding of the learning experiences of adult Latino college students, as described directly in their own voices. The study was guided by two research questions: RQ1: "How do adult Latinos describe their undergraduate college learning experiences?" and RQ2: "How do culture, gender, and ethnic…

  16. Expresiones de Desarrollo Profesional en Educadoras Principiantes y con Experiencia.

    ERIC Educational Resources Information Center

    Betsalel-Presser, Raquel

    1986-01-01

    Attempts to identify the conditions which affect the professional development of both experienced and inexperienced teachers. After presenting the theoretical and conceptual framework of the problem, discusses professional development needs identified by preschool and primary school teachers in an exploratory study done in Montreal, Quebec…

  17. Nuestros Sentimientos Son Iguales, La Diferencia Es En La Experiencia

    ERIC Educational Resources Information Center

    Palomares, Uvaldo H.

    1971-01-01

    The author concludes that counselors may be the prime cause of miscommunication and prejudicial evaluation in relations with persons from divergent racial and ethnic groups. Counselors must recognize and value the ethnicity of other persons if they are to foster an open, trusting, and productive counseling relationship with them. (Author/BY)

  18. La Experiencia Mexicana (The Mexican Experience). Volumes I and II.

    ERIC Educational Resources Information Center

    Finer, Neal B.

    Designed to be used as part of a comprehensive social studies program on Mexican culture, this two-volume manual, written in Spanish, offers an instructional package on Mexican culture, stressing an art-architecture perspective, which can be used at the secondary, college and adult levels. The teacher's guide, Volume I, includes a discussion of a…

  19. [Syringomyelias in paediatrics: a retrospective study of 25 cases].

    PubMed

    Martinez-Albaladejo, I; Prochazkova, M; Perez-Sebastian, I; Bernardino-Cuesta, B; Martinez-Ferrandez, C; Suarez-Traba, O M; Budke, M; Garcia-Penas, J J

    2016-09-01

    Introduccion. Se define siringomielia como una cavidad que contiene liquido cefalorraquideo dispuesta en el interior de la medula espinal. Objetivo. Describir las caracteristicas clinicas de una serie de pacientes con siringomielia, su diagnostico y tratamiento. Pacientes y metodos. Estudio descriptivo retrospectivo realizado mediante la revision de historias clinicas en nuestro centro. Resultados. Se revisaron 25 pacientes diagnosticados de siringomielia. En cinco el diagnostico fue casual y ocho presentaban una patologia grave previa (tumoral, osea o vascular). Dos pacientes comenzaron con hidrocefalia y clinica de hipertension intracraneal y unicamente dos destacaban cefalea como unico sintoma. Cuatro presentaron escoliosis progresiva, dos de ellos como queja inicial, y precisaron cirugia con artrodesis y uso de corse, respectivamente. Destaca la precocidad del diagnostico. La mayoria presentaba unicamente perdida de fuerza leve, con potenciales somatosensoriales y electromiograma normales. En todos se hicieron controles con resonancia magnetica. Ocho pacientes precisaron craniectomia descompresiva con laminectomia posterior C1-C2, con drenaje de la cavidad siringomielica en cuatro. Nueve requirieron valvula de derivacion y dos precisaron, ademas, ventriculostomia. Conclusiones. La presencia de siringomielia en pediatria es rara, y se asocia generalmente a malformaciones en la fosa posterior y antecedentes de disrafismo espinal. Destaca la escoliosis progresiva como posible manifestacion aislada. Un abordaje multidisciplinar con controles radiologicos seriados y la valoracion por servicios de neurologia y neurocirugia pediatricos son mandatorios para su seguimiento.

  20. Una experiencia europea de innovacion pedagogica basada en la escritura de un ibro.

    ERIC Educational Resources Information Center

    Montane, Mireia; Roc, Merce

    2002-01-01

    Describes a European project based on writing a book from an educational perspective. Participants included 18 schools from 13 countries. The study originated in a Spanish Comenius 3.1 project, which determined that university teams would visit "book writing" schools, supporting teachers and analyzing and publishing their experiences.…

  1. Profesionalismo: Un estudio fenomenologico sobre experiencias de universitarios en programas de salud

    NASA Astrophysics Data System (ADS)

    Lopez Ortiz, Wilma J.

    Some studies suggest that, upon admission, medicine programs students display eagerness for community service, aspirations to be useful, and to contribute to society's well-being. Those same studies reflect that qualities of idealism, moral nature, and internal motivation, suffer a subsequent diminishing. The researchers inferred that the main reason for this process of change in the mood and disposition of these future physicians lies in the modeling they receive from medical professionals throughout clinical learning activities, by way of behavior and relationships exhibited during daily interaction with peers, patients and the students themselves. This phenomenological study used a cross-sectional sample to explore the experiences of future health workers as they went through didactic and clinical phases of their training curriculum. The study employed semi-structured interviews and reflective journals to explore those experiences and to discover the meanings ascribed by the participants. The analysis revealed that the students defined "professionalism" in terms of scientific knowledge, commitment, respect for human dignity, comradeship, courtesy, empathy, integrity, altruism, motivation. They also described their feelings as they went through the didactic and clinical experiences, and recognized as very important the extracurricular activities of community service, describing them as useful opportunities which contributed to understand their work in terms of a mission dedicated to the achievement of the social benefit. From their individual perspectives, the clinical environment could, in general, be described as congruent with those characteristics of professionalism. During the study we had the opportunity to share, in a little deeper way, the environment... the world... of this small group of young students as we went on trying to decipher their feelings and thoughts. At the end, we realized the richness of their sensibilities, we perceived the intensity of their moral and ethical convictions, we were able to understand their concerns, worries, struggles and efforts. This life event had profound and significant repercussions in our personal and professional life. As a result, and from now on, we will no longer look at our young scholars and apprentices without imagining a noble spirit, with goals which at times could seem unattainable... without completely visualizing or conceiving real hope for a better country.

  2. Experiencias y avatares en la instalación local del programa ATLAS

    NASA Astrophysics Data System (ADS)

    Merlo, D. C.; Milone, L. A.

    In this paper we briefly describe the steps required for installation of AT- LAS code by Robert Kurucz. Subsequently, we summarize its implementa- tion and its comparison with our code MAPCOR, finding agreement on the structures of pressure when we look deeper layers, but some discrepancies in outer layers due to its limitations. FULL TEXT IN SPANISH

  3. Nuestras Experiencias: A Phenomenological Study of Latina First Generation Higher Education Graduates

    ERIC Educational Resources Information Center

    Cruz, Diana E.

    2012-01-01

    A review of the literature indicates that Latinos lag behind White and African American students in higher education degree attainment. This educational gap is of concern because Latinos are the largest minority group in the United States, and the Latino population is expected to increase in the future. Higher education degree attainment for…

  4. Una Experiencia Pedagogica en el Jardin Infantil "La Cabana" (A Teaching Experience in "La Cabana" Kindergarten).

    ERIC Educational Resources Information Center

    de la Vega, B.

    1992-01-01

    Reviews the history of La Cabana kindergarten, which provides preschool education and meals for 100 children and sewing classes for mothers in a working class neighborhood in Bogota, Colombia. Describes the implementation of a new curriculum which develops child creativity through free choice of activities around a common project. (AC)

  5. Una Experiencia Pedagogica en el Jardin Infantil "La Cabana" (A Teaching Experience in "La Cabana" Kindergarten).

    ERIC Educational Resources Information Center

    de la Vega, B.

    1992-01-01

    Reviews the history of La Cabana kindergarten, which provides preschool education and meals for 100 children and sewing classes for mothers in a working class neighborhood in Bogota, Colombia. Describes the implementation of a new curriculum which develops child creativity through free choice of activities around a common project. (AC)

  6. Una experiencia europea de innovacion pedagogica basada en la escritura de un ibro.

    ERIC Educational Resources Information Center

    Montane, Mireia; Roc, Merce

    2002-01-01

    Describes a European project based on writing a book from an educational perspective. Participants included 18 schools from 13 countries. The study originated in a Spanish Comenius 3.1 project, which determined that university teams would visit "book writing" schools, supporting teachers and analyzing and publishing their experiences.…

  7. Significant Learning Experiences for English Foreign Language Students (Experiencias significativas para estudiantes de inglés como lengua extranjera)

    ERIC Educational Resources Information Center

    Becerra, Luz María; McNulty, Maria

    2010-01-01

    This action research examines experiences that students in a grade 10 EFL class had with redesigning a grammar-unit into a topic-based unit. Strategies were formulating significant learning goals and objectives, and implementing and reflecting on activities with three dimensions of Dee Fink's (2003) taxonomy of significant learning: the human…

  8. Las experiencias clinicas de los estudiantes de enfermeria: Estudio de caso hacia la integracion de la mentoria

    NASA Astrophysics Data System (ADS)

    Rivera Rodriguez, Ivelisse

    Clinical experiences are an essential part of the training of future nursing professionals. The period of clinical experience aims to develop in the student the necessary skills to practice as a nursing professional, when the academic program ends. This case study aimed to understand the opinion and explore the perception of faculty, clinical instructors, and nursing students on the meaning, contributions and challenges presented during clinical experiences. Among the themes explored in the focus groups were the meaning and importance to learning about the profession of clinical experiences, teaching strategies used during the practice scenarios, didactic relationships developed among students, clinical instructors, and teachers. The goal was to learn from all participants about what they do, their expectations, and the challenges presented during the clinical experiences. A qualitative, descriptive and contextual research design was followed, which required conducting six focus groups to collect the information from the perspective of all the participants. Faculty, clinical instructors, and nursing students participated each in two focus groups. Collected data were transcribed, coded and analyzed in order to organize it under themes related to the research framework. The qualitative analysis of the focus groups revealed that nursing faculty and clinical instructors perceived clinical experiences as a very important element in the training of nursing students, but that coordination between the academy and practice scenarios is disconnected and needs improvement. They also expressed that they use various learning strategies during the clinical experiences, however, they recognize it needs more structure and suggested mentoring as a strategy to consider. They affirmed that mentoring could contribute positively to enhance the teaching-learning process. Clinical instructors understand they perform mentoring roles, but they would like to have a more defined role and structured process. Nursing students, also, recognized the importance of clinical experiences in their professional training. They expressed the need to improve the communication between the academy and the practice scenarios in order to reduce the levels of anxiety they experience when entering the clinical experiences. Nursing students also expressed the need to consider the use of different teaching strategies, such as mentoring, to improve clinical experiences.

  9. En el seno del hogar. Experiencias familiares para desarrollar el alfabetismo (Right at Home. Family Experiences for Building Literacy).

    ERIC Educational Resources Information Center

    Hansen, Merrily P.; Armstrong, Gloria

    This publication, a Spanish translation of "Right at Home," is a family involvement program in the form of easy-to-read cartoon-style letters to be used at home by parents or other family members with their preschool or kindergarten-age children. The book is designed to be used independently by parents, or to be reproduced and distributed to…

  10. La Cooperacion Internacional en Educacion: Estudio De La Experiencia Peruana. (International Cooperation in Education: Case Study of the Peruvian Experience).

    ERIC Educational Resources Information Center

    Chiappo, Leopoldo

    Educational development in Peru is discussed as part of a series surveying UNESCO's involvement in educational cooperation with developing nations. There are seven chapters to the report, which is written in Spanish. The first chapter describes Peru's national education policy, and discusses how it relates to the country's plan for national…

  11. En el seno del hogar. Experiencias familiares para desarrollar el alfabetismo (Right at Home. Family Experiences for Building Literacy).

    ERIC Educational Resources Information Center

    Hansen, Merrily P.; Armstrong, Gloria

    This publication, a Spanish translation of "Right at Home," is a family involvement program in the form of easy-to-read cartoon-style letters to be used at home by parents or other family members with their preschool or kindergarten-age children. The book is designed to be used independently by parents, or to be reproduced and distributed to…

  12. Encefalitis por anticuerpos contra el receptor de NMDA: experiencia con seis pacientes pediátricos. Potencial eficacia del metotrexato

    PubMed Central

    Bravo-Oro, Antonio; Abud-Mendoza, Carlos; Quezada-Corona, Arturo; Dalmau, Josep; Campos-Guevara, Verónica

    2016-01-01

    Introducción La encefalitis por anticuerpos contra el receptor de N-metil-D-aspartato (NMDA) es una entidad cada vez más diagnosticada en edad pediátrica. A diferencia de los adultos, en muchos casos no se asocia a tumores y las manifestaciones iniciales en niños más frecuentes son crisis convulsivas y trastornos del movimiento, mientras que en los adultos predominan las alteraciones psiquiátricas. Casos clínicos Presentamos seis casos pediátricos confirmados con anticuerpos contra la subunidad NR1 del receptor de NMDA en suero y líquido cefalorraquídeo. Cinco de los casos comenzaron con crisis convulsivas como manifestación clínica inicial antes de desarrollar el cuadro clásico de esta entidad. En todos los casos se utilizaron esteroides como primera línea de tratamiento, con los que sólo se observó control de las manifestaciones en uno, por lo que el resto de los pacientes requirió inmunomoduladores de segunda línea. Todos los pacientes recibieron metotrexato como tratamiento inmunomodulador para evitar recaídas y la evolución fue a la mejoría en todos ellos. Conclusiones En nuestra serie de pacientes con encefalitis por anticuerpos contra el receptor de NMDA, ninguno se asoció a tumores. Todos los casos recibieron metotrexato por lo menos durante un año, no observamos eventos adversos clínicos ni por laboratorio, ni hubo secuelas neurológicas ni recaídas durante el tratamiento. Aunque es una serie pequeña y es deseable incrementar el número y tiempo de evolución, consideramos el metotrexato una excelente alternativa como tratamiento inmunomodulador para esta patología. PMID:24150952

  13. La Cooperacion Internacional en Educacion: Estudio De La Experiencia Peruana. (International Cooperation in Education: Case Study of the Peruvian Experience).

    ERIC Educational Resources Information Center

    Chiappo, Leopoldo

    Educational development in Peru is discussed as part of a series surveying UNESCO's involvement in educational cooperation with developing nations. There are seven chapters to the report, which is written in Spanish. The first chapter describes Peru's national education policy, and discusses how it relates to the country's plan for national…

  14. Como Lo Hago Yo: Tratamiento Quirurgico Del Mielomeningocele

    PubMed Central

    Portillo, Santiago

    2014-01-01

    En Argentina hay plan de fortificación con ácido fólico. Diagnostico prenatal no siempre es correcto. Cierre según técnica. Cerramos músculo. No favorecemos corpectomía temprana en casos de cifosis. Suturamos la plaqueta. Cerramos el plano muscular. Hidrocefalia: Válvula de derivación, generalmente dentro de los dos primeros meses. Ventriculostomía no está indicada. Chiari II. Laminectomia cervical alta. Siringomielia: Derivación desde la cavidad al peritoneo. PMID:24791219

  15. Trends in pesticide concentrations in urban streams in the United States, 1992-2008

    USGS Publications Warehouse

    Ryberg, Karen R.; Vecchia, Aldo V.; Martin, Jeffrey D.; Gilliom, Robert J.

    2010-01-01

    Pesticide concentration trends in streams dominated by urban land use were assessed using data from 27 urban streams sampled as part of the U.S. Geological Survey National Water-Quality Assessment Program. The sites were divided into four regions, Northeast, South, Midwest, and West, to examine possible regional patterns. Three partially overlapping 9-year periods (1992-2000, 1996-2004, and 2000-2008) were examined for eight herbicides and one degradation product (simazine, prometon, atrazine, deethylatrazine, metolachlor, trifluralin, pendimethalin, tebuthiuron, and Dacthal), and five insecticides and two degradation products (chlorpyrifos, malathion, diazinon, fipronil, fipronil sulfide, desulfinylfipronil, and carbaryl). The data were analyzed for trends in concentration using a parametric regression model with seasonality, flow-related variability, and trend, called SEAWAVE-Q. The SEAWAVE-Q model also was used to generate estimated daily concentration percentiles for each analysis period to provide a summary of concentration magnitudes. For herbicides, the largest 90th percentiles of estimated concentrations for simazine were in the South, prometon at some sites in all of the regions, atrazine and deethylatrazine in the South and Midwest, metolachlor in the Midwest and a few sites in the South, pendimethalin at scattered sites in all of the regions, and tebuthiuron in the South and a few sites in the Midwest and West. For insecticides, the largest 90th percentiles of estimated concentrations for diazinon and carbaryl were distributed among various sites in all regions (especially during 1996-2004), and fipronil at isolated sites in all of the regions during 2000-2008. Trend analysis results for the herbicides indicated many significant trends, both upward and downward, with varying patterns depending on period, region, and herbicide. Overall, deethylatrazine showed the most consistent pattern of upward trends, especially in the Northeast (2000-2008), South

  16. Yo, Ciudadano: Un Curriculo de Experiencias para Educacion Civica. Nivel: Kindergarten (Citizen Me: An Experiential Curriculum for Citizenship Education. Level: Kindergarten).

    ERIC Educational Resources Information Center

    Vardeman, Lou

    Integrating concepts of basic citizenship education with community involvement, this experiential curriculum provides a means for developing decision making and critical thinking skills within the existing social studies curriculum at the kindergarten level. Consisting of 11 lessons, the guide, written in Spanish, introduces the meaning of rules,…

  17. Formacion de Formadores: Experiencias Institucionales en Planeamiento y Administracion de la Educacion. (The Formation of Educational Planners: Institutional Experiences in Planning and Administration for Education.

    ERIC Educational Resources Information Center

    Senen Gonzalez, Silvia N. de

    Information collected from interviews with 15 ministers of education and 30 program directors and researchers at 18 universities in Venezuela, Costa Rica, Chile, Mexico, Colombia, Brazil, and Argentina is used to study academic programs which prepare persons to be educational planners and administrators. Section one describes background…

  18. Experiencias de Vida de la Mujer Adulta: Estudio de Caso de Lideres en Desarrollo del Programa de Administracion y Supervision Educativa

    ERIC Educational Resources Information Center

    Morales-Roman, Gildrette M.

    2012-01-01

    Since the twentieth century to present, the role of women in society has undergone fundamental changes. Women, today, has assumed many different task and new roles, becoming part of professional workforce and increasing level of education by aspiring a higher education gaining access to leadership positions. The purpose of this qualitative…

  19. Yo Ciudadano: Un Curriculo de Experiencias para Educacion Civica. Nivel: Cuatro (Citizen Me: An Experiential Curriculum for Citizenship Education. Level: Four).

    ERIC Educational Resources Information Center

    Lazarine, Dianne

    Integrating concepts of basic citizenship education with community involvement, this experiential curriculum provides a means for developing decision making and critical thinking skills within the existing fourth grade social studies curriculum. The 11 lessons, translated into into Spanish, cover the following concepts: responsibility in the care…

  20. Yo Ciudadano: Un Curriculo de Experiencias para Educacion Civica. Nivel: Cuatro (Citizen Me: An Experiential Curriculum for Citizenship Education. Level: Four).

    ERIC Educational Resources Information Center

    Lazarine, Dianne

    Integrating concepts of basic citizenship education with community involvement, this experiential curriculum provides a means for developing decision making and critical thinking skills within the existing fourth grade social studies curriculum. The 11 lessons, translated into into Spanish, cover the following concepts: responsibility in the care…

  1. El Poder de Cambiar: La Experiencia del Proyecto Costa Atlantica de Colombia (The Power To Change: The Experience of the Atlantic Coast Project in Columbia, 1977-1989).

    ERIC Educational Resources Information Center

    Chetley, Andrew

    In 1977, the Bernard van Leer Foundation began supporting a project in Colombia that had the objective of improving the quality of early childhood care and education in a small village. The Costa Atlantica project offered an approach to development that was based on community organization, social management, participation, cooperation, popular…

  2. Experiencias en Lenguaje Para su Nino ed Edad Pre-escolar. Parte I: Actividades Para la Casa. (Language Experiences for Your Preschooler. Part I: Activities at Home.)

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of Continuing Education Curriculum Development.

    The purpose of this manuscript (written in Spanish) is to encourage the development of communication skills of preschool children by introducing their parents to a number of learning activities suitable for home use. It is written to be used by an instructor who is working with preschool parents. The activities, which are designed to be…

  3. Teachers' Knowledge of Second Language and Curriculum: A Narrative Experience (Conocimiento de los profesores acerca de la segunda lengua y el currículo: una experiencia narrativa)

    ERIC Educational Resources Information Center

    Mendieta Aguilar, Jenny Alexandra

    2011-01-01

    This study was carried out with a group of three teachers who work for the foreign languages department of a private university in Colombia. It was aimed at unveiling and characterizing the narrative knowledge these teachers hold about language teaching and learning processes as well as the role this knowledge plays in the constant construction…

  4. Experiencias en Lenguaje Para su Nino ed Edad Pre-escolar. Parte I: Actividades Para la Casa. (Language Experiences for Your Preschooler. Part I: Activities at Home.)

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of Continuing Education Curriculum Development.

    The purpose of this manuscript (written in Spanish) is to encourage the development of communication skills of preschool children by introducing their parents to a number of learning activities suitable for home use. It is written to be used by an instructor who is working with preschool parents. The activities, which are designed to be…

  5. Experiencia Pedagogica con Adolescentes Paraliticos Cerebrales: La Musica, Un Elemento Rehabilitador (A Pedagogical Experience with Teenage Cerebral Paralytics Using Music as a Rehabilitating Element).

    ERIC Educational Resources Information Center

    Colomer, Marta; And Others

    The monograph describes efforts carried out in the Department of Work Therapy of a center for cerebral paralysis in Barcelona, Spain. The rehabilitation program incorporated music and movement in an attempt to develop the musical ear, sensitivity, and a sensorial education. The program stresses rhythm, melody, harmony, voice, musical audition, and…

  6. Experiencias, Sentido y Significado de la Consejeria en Justicia Social a Nivel Universitario: Estudio de Caso Cualitativo Mediante Tres Narrativas De Consejeros Profesionales en Educacion Superior

    ERIC Educational Resources Information Center

    Santiago Tosado, Virginia

    2012-01-01

    The purpose of the study was to understand and profoundly describe the nature of social justice practice, as is comes up from the experience of three professional counselors whose working settings are the academic arena. Detailed descriptions are presented concerning the meanings and sense of counseling for social justice, as the interviews…

  7. Experiencias de Vida de la Mujer Adulta: Estudio de Caso de Lideres en Desarrollo del Programa de Administracion y Supervision Educativa

    ERIC Educational Resources Information Center

    Morales-Roman, Gildrette M.

    2012-01-01

    Since the twentieth century to present, the role of women in society has undergone fundamental changes. Women, today, has assumed many different task and new roles, becoming part of professional workforce and increasing level of education by aspiring a higher education gaining access to leadership positions. The purpose of this qualitative…

  8. Experiencias Educativas en el Medio Rural Colombiano. Serie Divulgacion No. 2. [Educational Experiences in the Rural Colombian Milieu. Circulation Series No. 2].

    ERIC Educational Resources Information Center

    Ministerio de Educacion Nacional, Bogota (Colombia). Centro Nacional de Documentacion e Informacion Pedagogica.

    In fulfillment of the Colombian National Government's educational policy aimed toward improving the rural population's level of living, two fundamental projects have been implemented. These projects have led to the creation of schools, the continuous extension of grades, and the creation of "Concentraciones de Desarrollo Rural." They…

  9. Experiencias y repercusión de una formación en ética de investigación

    PubMed Central

    Rupaya, Carmen Rosa García

    2012-01-01

    El presente artículo tiene como propósito describir los logros y repercusiones de la capacitación en ética de la investigación que brinda el Centro Interdisciplinario de Estudios en Bioética de la Universidad de Chile, sirviendo de estímulo, motivación y orientación a profesionales que requieren conocer y aplicar las normas y el raciocinio conducente a la deliberación de los problemas en esta disciplina. Asimismo, describe cómo este conocimiento genera un efecto multiplicador en aspectos tales como la participación en un comité de ética de la investigación (CEI), organización de cursos y creación y desarrollo de líneas de investigación, que repercuten en publicaciones realizadas con estudiantes de posgrado. Relata además los contenidos y estrategias didácticas que pueden ser empleados en cursos de ética y bioética para estudiantes de estomatología y concluye mencionando la aplicación práctica de esta capacitación en los ámbitos docente, institucional y de investigación. PMID:24482556

  10. The Combine Project: An Experience in a Dual-Language Classroom = El proyecto de la cosechadora: una experiencia en una clase bilingue.

    ERIC Educational Resources Information Center

    Wilson, Rebecca

    This article, also available in Spanish, describes what happened when a bilingual kindergarten class in West Liberty, Iowa, investigated a combine. The dual-language Kindergarten program supports content area instruction in both Spanish and English. The first part of the article tells the story of the Combine Project, this class's first project…

  11. Yo, Ciudadano: Un Curriculo de Experiencias para Educacion Civica. Nivel: Kindergarten (Citizen Me: An Experiential Curriculum for Citizenship Education. Level: Kindergarten).

    ERIC Educational Resources Information Center

    Vardeman, Lou

    Integrating concepts of basic citizenship education with community involvement, this experiential curriculum provides a means for developing decision making and critical thinking skills within the existing social studies curriculum at the kindergarten level. Consisting of 11 lessons, the guide, written in Spanish, introduces the meaning of rules,…

  12. Historia Oral, Experiencias de Aprendizagem e Enraizamento Sociocultural--Um Projeto em Curso (Oral History, Learning Experiences, and Sociocultural Setting--A Project in Process).

    ERIC Educational Resources Information Center

    Vidigal, Luis

    1995-01-01

    Examines education and childhood in Portugal. Uses oral history methods in an educational context, exploring oral statements pedagogically. Considers these statements especially suitable to maintaining aspects of collective memory and social identity, reinforcing students' national and regional identities. Suggests this is very important in…

  13. The Combine Project: An Experience in a Dual-Language Classroom = El proyecto de la cosechadora: una experiencia en una clase bilingue.

    ERIC Educational Resources Information Center

    Wilson, Rebecca

    This article, also available in Spanish, describes what happened when a bilingual kindergarten class in West Liberty, Iowa, investigated a combine. The dual-language Kindergarten program supports content area instruction in both Spanish and English. The first part of the article tells the story of the Combine Project, this class's first project…

  14. Yo Ciudadano: Un Curriculo de Experiencias para Educacion Civica. Nivel: Uno (Citizen Me: An Experiential Curriculum for Citizenship Education. Level: One).

    ERIC Educational Resources Information Center

    Loftin, Richard

    Integrating concepts of basic citizenship education with community involvement, this experiential curriculum, written in Spanish, provides a means for developing decision making and critical thinking skills within the existing social studies curriculum in grade 1. Using short stories, field trips, and class discussions, the 11 lessons on…

  15. Planteamientos multiculturales en la educacion: una experiencia alemana. Studies and Evaluation Papers 14. (Multicultural Approaches in Education: A German Experience. Studies and Evaluation Papers 11).

    ERIC Educational Resources Information Center

    Treppte, Carmen

    This paper describes the development of Turkish Children and Mothers, a project designed to help 5-year-old preschoolers in the Ruhr Valley of Germany develop linguistic, motor, cognitive, and social abilities. The paper also describes various aspects of the project, including those that relate to maternal involvement, educational facilities, the…

  16. Yo Ciudadano: Un Curriculo de Experiencias para Educacion Civica. Nivel: Dos (Citizen Me: An Experiential Curriculum for Citizenship Education. Level: Two).

    ERIC Educational Resources Information Center

    Lantz, Jean

    Integrating concepts of basic citizenship education with community involvement, this experiential curriculum provides a means for developing decision making and critical thinking skills within the existing second grade social studies curriculum. The 10 lessons, translated into Spanish, cover the following concepts: friendly, unfriendly and…

  17. Yo Ciudadano: Un Curriculo de Experiencias para Educacion Civica. Nivel: Cinco (Citizen Me: An Experiential Curriculum for Citizenship Education. Level: Five).

    ERIC Educational Resources Information Center

    Gutierrez, Merri

    Integrating concepts of basic citizenship education with community involvement, this experiential curriculum provides a means for developing decision making and critical thinking skills within the existing fifth grade social studies curriculum. The 12 lessons, translated into Spanish, cover the following concepts: responsibility, rules and laws,…

  18. En Busqueda de la Escuela del Siglo XXI: Dos Experiencias de Autoaprendizaje (In Search of the 21st Century School: Two Self-Learning Experiences).

    ERIC Educational Resources Information Center

    Schiefelbein, Ernesto; And Others

    This book is a contribution to the dialogue that is maintained today around the problems of education. The book contains four parts: (1) "In Search of the 21st Century School. Can the Colombian New School (EN) Show Us the Way?"; (2) "Experimentation with Self-Learning Materials in Two Schools in Conchali (Chile)"; (3)…

  19. Yo Ciudadano: Un Curriculo de Experiencias Para Educacion Civica. Nivel: Tres (Citizen Me: An Experiential Curriculum for Citizenship Education. Level: Three).

    ERIC Educational Resources Information Center

    Javora, Angela

    Integrating concepts of basic citizenship education with community involvement, this experiential curriculum provides a means for developing decision making and critical thinking skills within the existing third grade social studies curriculum. The 10 lessons, translated into Spanish, cover school rules as personal safety measures, consequences of…

  20. Historia Oral, Experiencias de Aprendizagem e Enraizamento Sociocultural--Um Projeto em Curso (Oral History, Learning Experiences, and Sociocultural Setting--A Project in Process).

    ERIC Educational Resources Information Center

    Vidigal, Luis

    1995-01-01

    Examines education and childhood in Portugal. Uses oral history methods in an educational context, exploring oral statements pedagogically. Considers these statements especially suitable to maintaining aspects of collective memory and social identity, reinforcing students' national and regional identities. Suggests this is very important in…

  1. Formacion de Formadores: Experiencias Institucionales en Planeamiento y Administracion de la Educacion. (The Formation of Educational Planners: Institutional Experiences in Planning and Administration for Education.

    ERIC Educational Resources Information Center

    Senen Gonzalez, Silvia N. de

    Information collected from interviews with 15 ministers of education and 30 program directors and researchers at 18 universities in Venezuela, Costa Rica, Chile, Mexico, Colombia, Brazil, and Argentina is used to study academic programs which prepare persons to be educational planners and administrators. Section one describes background…

  2. EXPERIENCIAS RELACIONADAS A UNA INTERVENCIÓN PARA REDUCIR EL ESTIGMA RELACIONADO AL VIH/SIDA ENTRE ESTUDIANTES DE MEDICINA EN PUERTO RICO

    PubMed Central

    Cintrón-Bou, Francheska; Varas-Díaz, Nelson; Marzán-Rodríguez, Melissa; Neilands, Torsten B.

    2016-01-01

    Existe estigma relacionado al VIH. A las personas con VIH/SIDA-PCVS se les viola sus derechos y obstaculiza su bienestar mental/físico. Profesionales de la salud-PS son fuente de apoyo primordial, sin embargo estos/as le estigmatizan. Es útil adiestrar a PS en relación al estigma social. Implantamos la intervención para reducir el estigma relacionado al VIH/SIDA con 507 estudiantes de medicina. Resultó ser una intervención efectiva, hubo reducción en los niveles de estigma a partir de nuestra intervención y diferencias significativas con el grupo control (p≤.05). Generar espacios de adiestramiento para atender el estigma relacionado al VIH/SIDA es pertinente para la psicología comunitaria porque colaboramos en la reducción de actitudes estigmatizantes que afectan adversamente la prevención de nuevas infecciones, la adherencia al tratamiento antirretroviral y la calidad de vida. PMID:27829690

  3. Experiencias, Sentido y Significado de la Consejeria en Justicia Social a Nivel Universitario: Estudio de Caso Cualitativo Mediante Tres Narrativas De Consejeros Profesionales en Educacion Superior

    ERIC Educational Resources Information Center

    Santiago Tosado, Virginia

    2012-01-01

    The purpose of the study was to understand and profoundly describe the nature of social justice practice, as is comes up from the experience of three professional counselors whose working settings are the academic arena. Detailed descriptions are presented concerning the meanings and sense of counseling for social justice, as the interviews…

  4. [Radiological percutaneous gastrostomy (GRP), 17 años de experiencia, serie de casos del hospital Universitario Virgen del Rocío].

    PubMed

    Navarro Falcón, Magnolia Del Carmen; Parejo Campos, Juana; Pereira Cunill, José Luis; García Luna, Pedro Pablo

    2014-10-25

    When assessing a patient nutritional support the state of the gastrointestinal tract is the most important point to consider, whenever possible we should choose the enteral nutrition (EN) over parenteral nutrition (PN) and recognized by its various advantages. The percutaneous gastrostomy (GRP) were introduced in clinical practice as an alternative to surgical gastrostomy (GQ). The speed, simplicity, low cost, low morbidity and low mortality of these techniques has allowed its rapid development.The feeding tubes types used were the balloon-retained devices catheter, the pig tail and the ballon-retained with gastropexia (gastropexia). It is a retrospective study of all patients who were placed GPR in the Virgen del Rocío University Hospital, Sevilla, between September 1996 and September 2013, which aims to study is to describe the characteristics of patients and the complications presented for different types of enteral feeding tubes used. GPR 186 were performed in 176 patients (135 males (76.70%), with an average duration of 303.6 days, the most frequent diseases were cancers of the head and neck 49.46%. The types of feeding tubes used were pigtail 118 (63.44%), balloon-retained devices 22 (11.83%), and gastropexia 46 (24.73%). The most common early complications in the pigtail group were early purulent exudate and early bleeding (2.5 and 3.4% respectively), while in the balloon catheter group the initial output of the probe was most frequent early complication (13.7%), none of these complications were observed in the group of gastropexy. The most common late complication was obstruction probe. The GPR is a safe technique with lower mortality of 1%; Low frequently of early and late complications. A better understanding of this technique can reduce the frequency of complications.

  5. Yo Ciudadano: Un Curriculo de Experiencias para Educacion Civica. Nivel: Uno (Citizen Me: An Experiential Curriculum for Citizenship Education. Level: One).

    ERIC Educational Resources Information Center

    Loftin, Richard

    Integrating concepts of basic citizenship education with community involvement, this experiential curriculum, written in Spanish, provides a means for developing decision making and critical thinking skills within the existing social studies curriculum in grade 1. Using short stories, field trips, and class discussions, the 11 lessons on…

  6. Experiencia Pedagogica con Adolescentes Paraliticos Cerebrales: La Musica, Un Elemento Rehabilitador (A Pedagogical Experience with Teenage Cerebral Paralytics Using Music as a Rehabilitating Element).

    ERIC Educational Resources Information Center

    Colomer, Marta; And Others

    The monograph describes efforts carried out in the Department of Work Therapy of a center for cerebral paralysis in Barcelona, Spain. The rehabilitation program incorporated music and movement in an attempt to develop the musical ear, sensitivity, and a sensorial education. The program stresses rhythm, melody, harmony, voice, musical audition, and…

  7. [Oropharyngeal dysphagia associated with Chiari I malformation and syringomyelia J].

    PubMed

    Cortés-Medina, Julio César; Cárdenas-Lara, Armando; Guerrero-Rascón, Carlos Alberto; Rodríguez-Bautista, Heber

    2014-01-01

    Antecedentes: la disfagia con afección neurológica constituye un dato clínico significativo en el diagnóstico de lesiones que justifiquen la compresión del tronco cerebral y los nervios craneales bajos. Objetivo: destacar la importancia del estudio de la disfagia en una paciente con malformación de Chiari tipo I y siringomielia, sin síntomas gastroenterológicos primarios. Caso clínico: se comunica el caso de una mujer de 62 años de edad con disfagia orofaríngea de seis años de evolución, cervicobraquialgia, ptosis palpebral y diplejía facial. Conclusiones: el estudio por resonancia magnética constituye un elemento fundamental para establecer el diagnóstico causal de la disfagia neurogénica.

  8. Recent rates of forest harvest and conversion in North America

    Treesearch

    Jeffrey G. Masek; Warren B. Cohen; Donald Leckie; Michael A. Wulder; Rodrigo Vargas; Ben de Jong; Sean Healey; Beverly Law; Richard Birdsey; R. A. Houghton; David Mildrexler; Samuel Goward; W. Brad. Smith

    2011-01-01

    Incorporating ecological disturbance into biogeochemical models is critical for estimating current and future carbon stocks and fluxes. In particular, anthropogenic disturbances, such as forest conversion and wood harvest, strongly affect forest carbon dynamics within North America. This paper summarizes recent (2000-2008) rates of extraction, including both conversion...

  9. 75 FR 2823 - Incorporating Employee Compensation Criteria Into the Risk Assessment System

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-19

    ... Street) on business days between 7 a.m. and 5 p.m. Instructions: All comments received will be posted... compensation practices contributed to the excessive build-up of risk that precipitated the crisis. A review of... and Lehman 2000-2008,'' Yale Journal on Regulation (forthcoming) ( http://www.law.harvard.edu/faculty...

  10. Action Research for Educational Reform: Remodelling Action Research Theories and Practices in Local Contexts

    ERIC Educational Resources Information Center

    Somekh, Bridget; Zeichner, Ken

    2009-01-01

    This paper explores how action research theories and practices are remodelled in local contexts and used to support educational reform. From an analysis of 46 publications from the period 2000-2008, five "variations" in the globalized theory and practice of action research are identified: action research in times of political upheaval and…

  11. Nesting ecology and nest success of the Blue Grosbeak along two rivers in New Mexico

    Treesearch

    Jean-Luc E. Cartron; Deborah M. Finch; David L. Hawksworth; Scott H. Stoleson

    2013-01-01

    From 1997 through 2008, we studied the nesting habits and nest success of the Blue Grosbeak (Passerina cerulean) along the middle Gila River (1997-2001) and the middle Rio Grande (2000-2008) in New Mexico. A riparian forest of cottonwoods grows along both rivers. but the forest along the Rio Grande is a much more intensively managed ecosystem, with an understory...

  12. Fostering Locomotor Behavior of Children with Developmental Disabilities: An Overview of Studies Using Treadmills and Walkers with Microswitches

    ERIC Educational Resources Information Center

    Lancioni, Giulio E.; Singh, Nirbhay N.; O'Reilly, Mark F.; Sigafoos, Jeff; Didden, Robert; Manfredi, Francesco; Putignano, Pietro; Stasolla, Fabrizio; Basili, Gabriella

    2009-01-01

    This paper provides an overview of studies using programs with treadmills or walkers with microswitches and contingent stimulation to foster locomotor behavior of children with developmental disabilities. Twenty-six studies were identified in the period 2000-2008 (i.e., the period in which research in this area has actually taken shape).…

  13. Learning in Communities of Inquiry: A Review of the Literature

    ERIC Educational Resources Information Center

    Rourke, Liam; Kanuka, Heather

    2009-01-01

    The purpose of this study was to investigate learning in communities of inquiry (CoI) as the terms are defined in Garrison, Anderson, and Archer's (2000) framework. We identified 252 reports from 2000-2008 that referenced the framework, and we reviewed them using Ogawan and Malen's (1991) strategy for synthesizing multi-vocal bodies of literature.…

  14. Legislating Language in Taiwan: From Equality to Development to Status Quo

    ERIC Educational Resources Information Center

    Dupré, Jean-François

    2016-01-01

    This paper looks into failed attempts by the Democratic Progressive Party's (DPP) minority government (2000-2008) to alter Taiwan's Mandarin-dominated language regime by drafting law proposals recognizing the languages of all Taiwanese ethnic groups as equal national languages. This paper argues that the failure to enact language regime change in…

  15. A Content Analysis of Kindergarten-12th Grade School-Based Nutrition Interventions: Taking Advantage of Past Learning

    ERIC Educational Resources Information Center

    Roseman, Mary G.; Riddell, Martha C.; Haynes, Jessica N.

    2011-01-01

    Objective: To review the literature, identifying proposed recommendations for school-based nutrition interventions, and evaluate kindergarten through 12th grade school-based nutrition interventions conducted from 2000-2008. Design: Proposed recommendations from school-based intervention reviews were developed and used in conducting a content…

  16. The Education for All Global Monitoring Report: A Mid-Term Assessment

    ERIC Educational Resources Information Center

    Packer, Steve

    2008-01-01

    The Education for All (EFA) Global Monitoring Report is six years old and seven reports have been produced (UNESCO, 2000-2008). It is a product of the outcomes of the World Education Forum in Dakar held in 2000. It is designed to track progress towards the realization of the six EFA goals and to hold governments and the international community to…

  17. A Content Analysis of Kindergarten-12th Grade School-Based Nutrition Interventions: Taking Advantage of Past Learning

    ERIC Educational Resources Information Center

    Roseman, Mary G.; Riddell, Martha C.; Haynes, Jessica N.

    2011-01-01

    Objective: To review the literature, identifying proposed recommendations for school-based nutrition interventions, and evaluate kindergarten through 12th grade school-based nutrition interventions conducted from 2000-2008. Design: Proposed recommendations from school-based intervention reviews were developed and used in conducting a content…

  18. Overeducation Dynamics and Personality

    ERIC Educational Resources Information Center

    Blazquez, Maite; Budria, Santiago

    2012-01-01

    In this paper, we use the 2000-2008 waves of the German Socioeconomic Panel to examine overeducation transitions. The results are based on a first-order Markov model that allows us to account for both the initial conditions problem and potential endogeneity in attrition. We found that overeducation dynamics, especially the probability of entering…

  19. Fostering Locomotor Behavior of Children with Developmental Disabilities: An Overview of Studies Using Treadmills and Walkers with Microswitches

    ERIC Educational Resources Information Center

    Lancioni, Giulio E.; Singh, Nirbhay N.; O'Reilly, Mark F.; Sigafoos, Jeff; Didden, Robert; Manfredi, Francesco; Putignano, Pietro; Stasolla, Fabrizio; Basili, Gabriella

    2009-01-01

    This paper provides an overview of studies using programs with treadmills or walkers with microswitches and contingent stimulation to foster locomotor behavior of children with developmental disabilities. Twenty-six studies were identified in the period 2000-2008 (i.e., the period in which research in this area has actually taken shape).…

  20. Leading with "Emotional" Intelligence--Existential and Motivational Analysis in Leadership and Leadership Development

    ERIC Educational Resources Information Center

    Mengel, Thomas

    2012-01-01

    This conceptual and practical paper is integrating the work of Viktor Frankl (1985) and Steven Reiss (2000, 2008) into a model of Existential and Motivational Analysis (EMotiAn). This integrated model and approach may provide scholars, educators, consultants and practitioners alike with an innovative and meaningful framework for leadership and…

  1. NSA AERI Hatch Correction Data Set

    DOE Data Explorer

    Turner, David

    2012-03-23

    From 2000-2008, the NSA AERI hatch was determined to be indicated as open too frequently. Analysis suggests that the hatch was actually opening and closing properly but that its status was not being correctly reported by the hatch controller to the datastream. An algorithm was written to determine the hatch status from the observed

  2. Legislating Language in Taiwan: From Equality to Development to Status Quo

    ERIC Educational Resources Information Center

    Dupré, Jean-François

    2016-01-01

    This paper looks into failed attempts by the Democratic Progressive Party's (DPP) minority government (2000-2008) to alter Taiwan's Mandarin-dominated language regime by drafting law proposals recognizing the languages of all Taiwanese ethnic groups as equal national languages. This paper argues that the failure to enact language regime change in…

  3. Understanding about Water in Liquid Modernity: Critical Imperatives for English Teaching

    ERIC Educational Resources Information Center

    Misson, Ray

    2012-01-01

    We are at a particularly difficult historical juncture marked by uncertainty, contingency and change. Zygmunt Bauman characterises the present time as "liquid modernity" (2000, 2008, 2011b) because of the fluidity and instability that we live with. Our identities and our relations to the world are changing radically. There is an urgent need for…

  4. Understanding about Water in Liquid Modernity: Critical Imperatives for English Teaching

    ERIC Educational Resources Information Center

    Misson, Ray

    2012-01-01

    We are at a particularly difficult historical juncture marked by uncertainty, contingency and change. Zygmunt Bauman characterises the present time as "liquid modernity" (2000, 2008, 2011b) because of the fluidity and instability that we live with. Our identities and our relations to the world are changing radically. There is an urgent need for…

  5. Publishing and Academic Writing: Experiences of Authors Who Have Published in "PROFILE" (Publicación y escritura académica: experiencias de autores que han publicado en "PROFILE")

    ERIC Educational Resources Information Center

    Cárdenas, Melba L.

    2014-01-01

    The increase in the publication of academic journals is closely related to the growing interest of research communities as well as of institutional policies that demand visibility of the work done by their staff through publications in highly-ranked journals. The purpose of this paper is to portray the experiences of some authors who published…

  6. Self-Access Language Learning: Students' Perceptions of and Experiences within This New Mode of Learning (Aprendizaje de idiomas mediante la modalidad de autoacceso: percepciones y experiencias de los estudiantes)

    ERIC Educational Resources Information Center

    Herrera Díaz, Luz Edith

    2012-01-01

    With the aim of fostering autonomy in learning, both innovations, the self-access centre and the mode of learning derived from it, were adopted in the context of the study (Language Centre in the University of Veracruz, Mexico). Based on a case study, I have adopted a qualitative perspective to do this research, which aimed to know how the…

  7. From Awareness to Cultural Agency: EFL Colombian Student Teachers' Travelling Abroad Experiences (De la concientización a la agencia cultural: las experiencias en el extranjero de futuros profesores de inglés)

    ERIC Educational Resources Information Center

    Viafara González, John Jairo; Ariza Ariza, J. Aleida

    2015-01-01

    Colombian English as a foreign language student teachers' opportunities to grow as educators through international sojourns do not usually subsume the traditional study and residence abroad goal. This was the case for our participants who engaged mainly in working abroad with study being ancillary. Fifty student teachers from two public…

  8. Mision Informacion: Entrevista a Empleados en el Lugar donde Trabajan; Observar a Obreros mientras Trabajan; Programa sobre Experiencia Laboral (Mission Information: Worksite Interview, Shadow Community Workers, Work Experience Program). CHOICE (Challenging Options in Career Education).

    ERIC Educational Resources Information Center

    Putnam and Northern Westchester Counties Board of Cooperative Educational Services, Yorktown Heights, NY.

    The work-study guide is the third volume in the advanced level of a career education curriculum for elementary-secondary migrant children. Complementing the secondary level job information text and a workbook about decision making and self-awareness, the work-study guide is designed to accompany work exploration and experience programs. It…

  9. Nuevas estrategias de gestión, tratamiento y valorización de los efluentes organicos pecuarios: Experiencias en USDA. (Management strategies for organic livestock effluents,innovative treatment and valorization)

    USDA-ARS?s Scientific Manuscript database

    En la actualidad el impacto potencial de los residuos ganaderos en el medio-ambiente representa uno de los desafíos más grandes de la agricultura. Las tecnologías de tratamiento pueden tener un importante papel en el manejo de los residuos ganaderos dando más flexibilidad en los programas de la apli...

  10. Adolescents' Awareness of Environmental Care: Experiences When Writing Short Descriptive Texts in English (Concientización de los adolescentes sobre el cuidado ambiental: experiencias al escribir textos descriptivos cortos en inglés)

    ERIC Educational Resources Information Center

    Jaramillo Urrutia, Lorena; Medina Gutiérrez, Ana Stella

    2011-01-01

    Today it is necessary to approach environmental topics with students in an interdisciplinary manner to mitigate the environmental damages that the Earth is suffering. In this paper we report an action-research and innovation study aimed at sensitizing students with respect to the care and preservation of the environment through the writing of…

  11. Relatorio Final Sobre o Ensino Bilingue: Resultados da Avaliacao Externa da Experiencia de Escolarizacao Bilingue em Mocambique (PEBIMO) (Final Report on Bilingual Education: Results of External Evaluation of an Experiment in Bilingual Education in Mozambique).

    ERIC Educational Resources Information Center

    Benson, Carolyn J.

    The PEBIMO project was designed to determine whether bilingual education could improve the quality of primary education in Mozambique, recognizing that Portuguese is not the native language of the majority of Mozambican students. The project began in 1992 with 8 cohorts of first grade in 2 provinces; during this investigation, students were in…

  12. Teacher: Can You See What I'm Saying? A Research Experience with Deaf Learners (Profe: ¿Puedes "ver" lo que estoy diciendo? Una experiencia de investigación con alumnos sordos)

    ERIC Educational Resources Information Center

    Ávila Caica, Olga Lucía

    2011-01-01

    This paper reports a study carried out with eleven deaf volunteers who belonged to different academic programs at a Colombian public university but did not receive English instruction as part of their professional training. The main goal of the research study was to identify the effect of using Internet resources as support for the design and…

  13. Gonorrhea infections diagnosed among persons living with HIV/AIDS: identifying opportunities for integrated prevention services in New York City, Washington, DC, Miami/Dade County, and Arizona.

    PubMed

    Taylor, Melanie M; Schillinger, Julia A; Furness, Bruce W; Brewer, Toye; Newman, Daniel R; Pathela, Preeti; Skinner, Julia; Braunstein, Sarah; Shepard, Colin; Ahmed, Tashrik; Griffin, Angelique; Blank, Susan; Peterman, Thomas A

    2013-09-01

    : Persons living with HIV/AIDS who acquire new sexually transmitted diseases (STDs) pose a risk for enhanced transmission of both HIV and STDs. To describe the frequency of HIV coinfection among gonorrhea cases (GC), HIV and GC surveillance databases (2000-2008) were cross-matched in New York City (NYC), Washington, DC (DC), Miami/Dade County (MDC), and Arizona (AZ). During 2000-2008, 4.6% (9471/205,689) of reported GCs occurred among persons with previously diagnosed HIV: NYC (5.5%), DC (7.3%), MDC (4%), and AZ (2%). The overall HIV-GC coinfection rates increased over the study period in all 4 sites. Real-time data integration could allow for enhanced prevention among persons with HIV infection and acute STDs.

  14. Land-use/land-cover change and ecosystem service provision in China.

    PubMed

    Song, Wei; Deng, Xiangzheng

    2017-01-15

    As a result of economics and policy, land-use/land-cover change (LUCC) in China has undergone a series of complicated changes over the past three decades. However, the effects of LUCCs on ecosystem service values (ESVs) have never been previously assessed at the national scale. Thus, on the basis of three Chinese LUCC maps from 1988, 2000, and 2008, we examined changes in land-use/land-cover and consequent ESVs using a value transfer method. We found that ESVs decreased by 0.45% and 0.10% during the periods 1988-2000 and 2000-2008, respectively, and that ESV changes in China during the period 2000-2008 were relatively moderate compared to the rest of the world over a similar period. The ESVs for provision, regulation, support, and culture decreased by 0.19%, 0.48%, 0.43%, and 0.45%, respectively, during the period 1988-2000, while they decreased by 0.11%, 0.09%, 0.14%, and 0.04%, respectively, during the period 2000-2008. We also developed an elasticity indicator to assess responses in ESV change relative to LUCCs. Results of this analysis show that 1% of land conversion in China resulted in 0.15% and 0.10% average changes in ESVs during the two periods, respectively. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. [The role of experience in the neurology of facial expression of emotions].

    PubMed

    Gordillo, Fernando; Pérez, Miguel A; Arana, José M; Mestas, Lilia; López, Rafael M

    2015-04-01

    Introduccion. La expresion facial de las emociones tiene una funcion social importante que facilita la interaccion entre las personas. Este proceso tiene una base neurologica, que no se aisla del contexto ni de la experiencia acumulada por la interaccion entre las personas en dicho contexto. Sin embargo, hasta la fecha, no se conocen con claridad los efectos de la experiencia sobre la percepcion de las emociones. Objetivos. Discutir que funcion desempeña la experiencia en el reconocimiento de la expresion facial de las emociones y analizar los sesgos que las experiencias negativas y positivas podrian tener sobre la percepcion emocional. Desarrollo. La maduracion de las estructuras que soportan la capacidad para reconocer la emocion pasa por un periodo sensible durante la adolescencia, donde la experiencia adquirida puede tener mayor impacto sobre el reconocimiento emocional. Experiencias de abuso, maltrato, abandono, guerras o estres generan un sesgo hacia las expresiones de ira y tristeza. De igual manera, las experiencias positivas dan lugar a un sesgo hacia la expresion de alegria. Conclusiones. Solo cuando las personas son capaces de utilizar la expresion facial de las emociones como un canal de comprension y expresion interaccionaran de manera adecuada con su entorno. Este entorno, a su vez, dara lugar a experiencias que modulan dicha capacidad. Por lo tanto, es un proceso autorregulatorio que puede ser dirigido a traves de la implementacion de programas de intervencion sobre los aspectos emocionales.

  16. Persistent high rates of smoking among Israeli Arab males with concomitant decrease among Jews.

    PubMed

    Baron-Epel, Orna; Keinan-Boker, Lital; Weinstein, Ruth; Shohat, Tamy

    2010-12-01

    During the last few decades much effort has been invested into lowering smoking rates due to its heavy burden on the population's health and on costs for the health care services. To compare trends in smoking rates between adult Arab men and Jewish men and women during 2000-2008. Six random telephone surveys were conducted by the Israel Center for Disease Control in 2000-2008 to investigate smoking rates. The number of respondents was 24,976 Jewish men and women and 2564 Arab men. The percent of respondents reporting being current smokers was calculated for each population group (Jews and Arabs) by age, gender and education, and were studied in relation to time. Among Jewish men aged 21-64 smoking declined during 2000-2008 by about 3.5%. In the 21-44 age group this decline occurred only among respondents with an academic education. Among Jewish women this decline also occurred at ages 21-64, and in the 45-64 age group this decline was due only to a decline in smoking among those with an academic education. Among Arab men aged 21-64 an increase in smoking rates of about 6.5% was observed among both educated and less educated respondents. Smoking prevalence is declining in Israel among Jews, but not among Arab men. The larger decrease in smoking rates among academics will, in the future, add to the inequalities in health between the lower and higher socioeconomic status groups and between Arabs and Jews. This calls for tailored interventions among the less educated Jews and all Arab men.

  17. Multilevel modeling of NPP change and impacts of water resources in the Lower Heihe River Basin

    NASA Astrophysics Data System (ADS)

    Yan, Haiming; Zhan, Jinyan; Jiang, Qun'ou; Yuan, Yongwei; Li, Zhihui

    Net primary productivity (NPP) lays the foundation for provision of various ecosystem services, and understanding the impacts of potential influencing factors on NPP is of great significance to formulating appropriate management measures to guarantee the sustainable provision of essential ecosystem services. This study analyzed the impacts of potential influencing factors on NPP in the lower Heihe River Basin, a typical arid and semi-arid region in China. First, NPP was estimated with the C-FIX model, and then the multilevel model was used to analyze the impacts of potential influencing factors on NPP during 2000-2008. Finally decomposition analysis was used to further analyze the contribution of influencing factors to NPP change during 2000-2008. The average NPP increased by approximately 9.07% during 2000-2008, and results of the multilevel model indicate that both the socioeconomic variables and demographic variables are useful in explaining NPP change. In particular, coefficients of rainfall and evapotranspiration which represent the water availability reached 0.0456 and 0.2956, respectively. Results of decomposition analysis suggested that the water availability played an important role in increasing NPP, with a contribution rate of 44.17%, and it is necessary to carry out some policies that can promote the water use efficiency to increase NPP under the background of climate change and intensified human activities. There are some uncertainties in the results of this study, but these results still can provide valuable reference information for the water resource management to increase the ecosystem service supply in the lower Heihe River Basin.

  18. Pregnancy termination in Matlab, Bangladesh: maternal mortality risks associated with menstrual regulation and abortion.

    PubMed

    Rahman, Mizanur; DaVanzo, Julie; Razzaque, Abdur

    2014-09-01

    In Bangladesh, both menstrual regulation (MR), which is thought to be a relatively safe method, and abortion, which in this setting is often performed using unsafe methods, are used to terminate pregnancies (known or suspected). However, little is known about changes over time in the use of these methods or their relative mortality risks. Data from the Demographic Surveillance System in Matlab, Bangladesh, on 110,152 pregnancy outcomes between 1989 and 2008 were used to assess changes in mortality risks associated with MR (and a small number of dilation and curettage procedures), abortion and live birth. Tabulation and logistic regression analyses were used to compare outcomes in two areas of Matlab--the comparison area, which receives standard government health and family planning services, and the Maternal and Child Health-Family Planning (MCH-FP) area, which receives enhanced health and family planning services. In Matlab as a whole, the proportion of pregnancies ending in MR increased from 1.9% in 1989-1999 to 4.2% in 2000-2008, while the proportion ending in abortion decreased from 1.6% to 1.1%. The odds of mortality from MR were 4.1 times those from live birth in 1989-1999, but were no longer elevated in 2000-2008. The odds of mortality from abortion were 12.0 and 4.9 times those of live birth in 1989-1999 and 2000-2008, respectively. Reduction in mortality risk was greater in the MCH-FP area than the comparison area (90% vs. 75%). MR is no longer associated with higher mortality risk than live birth in Bangladesh, but abortion is.

  19. Spatially distributed evapotranspiration and recharge estimation for sand regions of Hungary in the context of climate change

    NASA Astrophysics Data System (ADS)

    Csáki, Péter; Kalicz, Péter; Gribovszki, Zoltán

    2016-04-01

    Water balance of sand regions of Hungary was analysed using remote-sensing based evapotranspiration (ET) maps (1*1 km spatial resolution) by CREMAP model over the 2000-2008 period. The mean annual (2000-2008) net groundwater recharge (R) estimated as the difference in mean annual precipitation (P) and ET, taking advantage that for sand regions the surface runoff is commonly negligible. For the examined nine-year period (2000-2008) the ET and R were about 90 percent and 10 percent of the P. The mean annual ET and R were analysed in the context of land cover types. A Budyko-model was used in spatially-distributed mode for the climate change impact analysis. The parameters of the Budyko-model (α) was calculated for pixels without surplus water. For the extra-water affected pixels a linear model with β-parameters (actual evapotranspiration / pan-evapotranspiration) was used. These parameter maps can be used for evaluating future ET and R in spatially-distributed mode (1*1 km resolution). By using the two parameter maps (α and β) and data of regional climate models (mean annual temperature and precipitation) evapotranspiration and net groundwater recharge projections have been done for three future periods (2011-2040, 2041-2070, 2071-2100). The expected ET and R changes have been determined relative to a reference period (1981-2010). According to the projections, by the end of the 21th century, ET may increase while in case of R a heavy decrease can be detected for the sand regions of Hungary. This research has been supported by Agroclimate.2 VKSZ_12-1-2013-0034 project. Keywords: evapotranspiration, net groundwater recharge, climate change, Budyko-model

  20. [The dynamics of morbidity of population of the city of Ufa].

    PubMed

    Askarova, Z F; Baiykina, I M; Tchuyenkova, G A; Askarov, R A

    2012-01-01

    The article deals with analysis of general and primary morbidity of population of Ufa in all age groups according the data of form N 12 of state statistical supervision "The information of number of diseases registered in patients residing in the district of medical institution support" of Minzdrav of Republic of Bashkortostan in 2000-2008. It is established that during the mentioned period of time, an increase occurred of general and primary morbidity. The particular classes of diseases and age groups are detected which are characterized by a significant increase of indicators of morbidity.

  1. Exploring EFL Pre-Service Teachers' Experience with Cultural Content and Intercultural Communicative Competence at Three Colombian Universities (Indagación sobre la experiencia con el contenido cultural y la competencia comunicativa intercultural de docentes de inglés en formación, en tres universidades colombianas)

    ERIC Educational Resources Information Center

    Olaya, Alba; Gómez Rodríguez, Luis Fernando

    2013-01-01

    This article reports the findings of a qualitative research project that explored pre-service English teachers' perceptions of and attitudes toward the aspects of culture and intercultural competence addressed in their English classes in the undergraduate programs at three Colombian universities. Findings reveal that pre-service teachers are…

  2. New Educational Environments Aimed at Developing Intercultural Understanding while Reinforcing the Use of English in Experience-Based Learning (Nuevos entornos educativos destinados a desarrollar la comprensión intercultural y a reforzar el uso del inglés mediante el aprendizaje basado en experiencias)

    ERIC Educational Resources Information Center

    Bruguier, Leonard R.; Greathouse Amador, Louise M.

    2012-01-01

    New learning environments with communication and information tools are increasingly accessible with technology playing a crucial role in expanding and reconceptualizing student learning experiences. This paper reviews the outcome of an innovative course offered by four universities in three countries: Canada, the United States, and Mexico. Course…

  3. Experiencias interculturales y la pedagogia de la anglofonia en la ensenanza de ingles como lengua extranjera (EILE) desde una perspectiva deweyana. Working Paper (A Deweyan Perspective on Cross-Cultural Experiences and Anglophone Pedagogy in the Teaching of English as a Foreign Language. Working Paper).

    ERIC Educational Resources Information Center

    Zoreda, Margaret Lee

    This paper discusses a framework for teaching English as a foreign language that incorporates significant cultural content and fosters critical encounters with Anglophone culture. It reviews relevant contemporary perspectives for understanding cross-cultural processes within the foreign language teaching environment with emphasis on the issue of…

  4. Discrepancies in Lymphoma Diagnosis Over the Years: A 13-Year Experience in a Tertiary Center.

    PubMed

    Özkaya, Neval; Başsüllü, Nuray; Demiröz, Ahu Senem; Tüzüner, Nükhet

    2017-03-01

    In the past, accurate diagnosis of lymphoma was challenging since there were multiple competing classification systems that caused confusion and debate. After establishment of the World Health Organization lymphoma classification, lymphomas still remain a diagnostic challenge among general pathologists. The purpose of this study was to examine whether the discordance among centers has declined over the years. All lymphoma or lymphoma-suspected specimens that had been sent to the Cerrahpaşa Faculty of Medicine between 2000 and 2013 for a second opinion were deemed eligible. To evaluate the change in the discrepancy rates over time we compared the rates of revision between 2000-2008 and 2009-2013. A total of 1824 patients in two time periods met the inclusion criteria. The overall discordance rate was 45.6%. This rate showed significant variations between different histologic subtypes. Discordance rates also varied significantly over time and decreased from 51.3% in 2000-2008 to 38.7% in 2009-2013 (p<.0001). The high discordance rate, especially in the second period, indicates the need for easily accessible hematopathology consultation centers.

  5. Trends in the use of immunosuppressive agents by outpatients after renal transplantation at a medical center in southern Taiwan.

    PubMed

    Mao, P C-M; Lee, E K-L; Tseng, P-L

    2012-01-01

    Kidney transplantation has become an effective treatment for end-stage renal failure. This study analyzed trends in immunosuppressive agent use after renal transplantation at a medical center in southern Taiwan over a 9-year period (2000-2008) seeking to determine whether the trends were consistent with clinical trial outcomes and published guidelines. We identified adult outpatients who had diagnoses of renal transplantation and who had concurrent immunosuppressive drug claims. From 2000-2008, we discovered 39,189 prescriptions related to kidney transplantation. The overall medication consumption showed an increase from 4.9% to 31.9%. Cyclosporine was the main determinant of overall drug costs during these 9 years. The long-term prescribing trend for immunosuppressive use among renal transplantation outpatients showed a clear change during the course of the study. Tacrolimus and sodium mycophenolate/mycophenolate mofetil were used increasingly as combination therapy. However, our survey revealed that management of this transplantation population, especially regarding the use of either calcineurin inhibitor or corticosteroids, was based on potential long-term side effects. Copyright © 2012 Elsevier Inc. All rights reserved.

  6. Ectopic pregnancy rates and racial disparities in the Medicaid population, 2004-2008.

    PubMed

    Stulberg, Debra B; Cain, Loretta R; Dahlquist, Irma; Lauderdale, Diane S

    2014-12-01

    To assess 2004-2008 ectopic pregnancy rates among Medicaid recipients in 14 states and 2000-2008 time trends in three states and to identify differences in rate by race/ethnicity. Secondary analysis of Medicaid administrative claims data. Not applicable. Women ages 15-44 enrolled in Medicaid in Arizona, California, Colorado, Florida, Illinois, Indiana, Iowa, Louisiana, Massachusetts, Michigan, Minnesota, Mississippi, New York, or Texas in 2004-2008 (n = 19,135,106) and in California, Illinois, and New York in 2000-2003. None. Number of ectopic pregnancies divided by the number of total pregnancies (spontaneous abortions, induced abortions, ectopic pregnancies, and all births). The 2004-2008 Medicaid ectopic pregnancy rate for all 14 states combined was 1.40% of all reported pregnancies. Adjusted for age, the rate was 1.47%. Ectopic pregnancy incidence was 2.3 per 1,000 woman-years. In states for which longer term data were available (California, Illinois, and New York), the rate declined significantly in 2000-2008. In all 14 states, black women were more likely to experience an ectopic pregnancy compared with whites (relative risk, 1.46; 95% confidence interval, 1.45-1.47). Ectopic pregnancy remains an important health risk for women enrolled in Medicaid. Black women are at consistently higher risk than whites. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  7. Bulimia nerviosa

    MedlinePlus

    ... para orinar con frecuencia. Por lo general, la autoestima de las mujeres con bulimia está muy ligada ... biología de una persona, su imagen corporal y autoestima, sus experiencias sociales, antecedentes de salud familiares y ...

  8. Learning about the Sky from the Environment: An Experience Working Along One Year with Students of Elementary Education. (Spanish Title: Aprendiendo sobre EL Cielo Desde el Entorno: Una Experiencia Trabajando Durante un Año Junto a Estudiantes del Primario.) Aprendendo sobre o Céu a Partir do Entorno: Uma Experiência de Trabalho ao Longo de um Ano com Alunos de Ensino Fundamental

    NASA Astrophysics Data System (ADS)

    Longhini, Marcos Daniel; Gomide, Hanny Angeles

    2014-12-01

    Research developed with 95 students of the 6th year of elementary education in a public school of Uberlândia, Minas Gerais. It was a continuous work from February to December 2013, which led the students to participate in activities of observation of the environment, specifically the sky, analyzing the changes occurred. We focused on the study of variations in temperature, rainfall, day length, variations in the size of the shadows and changes in the aspect of the Moon. Our focus of analysis targeted the discussion of the knowledge that these students had about the topics indicated and as they entered the stage during the implementation of the proposal. The results showed a limited perception that students have of their environment, however, lately expanded due to the undertaken activities, especially in relation to the Moon. Working with systematic measure procedures reveals the careful handling of data so that they become understandable to students, and working with the shadows points towards the students first understand how shadows are formed, and then apply this knowledge to Astronomy. Finally, we conclude that the lived process consisted of an initial step of a work that should be encouraged for the subsequent years of training of these students. Proyecto de investigación desarrollado con 95 alumnos del sexto año de primaria en una escuela pública de Uberlândia, Minas Gerais. Fue un trabajo continuo, de febrero a diciembre de 2013, que llevó a los estudiantes a participar en actividades de observación de su entorno, entre ellas, el cielo, analizando los cambios ocurridos. Nos centramos en el estudio de las variaciones en la temperatura, las precipitaciones, la duración del día, las variaciones en el tamaño de las sombras y los cambios en los aspectos de la Luna. Nuestro foco de análisis se centró en discutir el conocimiento que estos estudiantes tenían sobre los temas indicados al inicio y término de la propuesta. Los resultados mostraron una percepción limitada que los estudiantes tienen de su alrededor la cual, sin embargo, se expandió debido a las actividades llevadas a cabo, sobre todo en relación con la Luna. Trabajar con medidas sistemáticas revela el manejo cuidadoso de los datos para que sean comprensibles para los estudiantes, así como el trabajo con las sombras para que comprendan primero como se forman estas para después trabajarlas en Astronomía. Por último, llegamos a la conclusión de que el proceso desarrollado consistió en una etapa inicial de una obra que debe ser profundizado en los años posteriores de la formación de estos estudiantes. Projeto de pesquisa desenvolvido com 95 alunos do 6º ano do Ensino Fundamental de uma escola pública estadual de Uberlândia, Minas Gerais. Foi um trabalho contínuo, de fevereiro a dezembro de 2013, o qual levou os alunos a participarem de atividades de observação do entorno, dentre ele, o céu, analisando as mudanças ocorridas. Focamos no estudo das variações de temperaturas, chuvas, duração do dia, variações do tamanho das sombras e mudanças nos aspectos da Lua. Nosso foco de análise centrou-se em discutir os conhecimentos que os referidos alunos tinham acerca dos temas indicados no início e ao término da implementação da proposta. Os resultados mostraram a percepção limitada que os estudantes possuem de seu entorno, todavia, ampliada em função das atividades desenvolvidas, principalmente no que se refere à Lua. O trabalho com medidas sistemáticas revela o cuidado no tratamento dos dados para que eles se tornem compreensíveis aos alunos, assim como o trabalho com as sombras sinaliza para que os alunos primeiramente compreendam como as sombras são formadas para depois trabalhar isso em Astronomia. Por fim, concluímos que o processo vivido constituiu-se em uma etapa inicial de um trabalho que deve ser estimulado para os anos subsequentes da formação desses alunos.

  9. Does a global budget superimposed on fee-for-service payments mitigate hospitals' medical claims in Taiwan?

    PubMed

    Hsu, Pi-Fem

    2014-12-01

    Taiwan's global budgeting for hospital health care, in comparison to other countries, assigns a regional budget cap for hospitals' medical benefits claimed on the basis of fee-for-service (FFS) payments. This study uses a stays-hospitals-years database comprising acute myocardial infarction inpatients to examine whether the reimbursement policy mitigates the medical benefits claimed to a third-payer party during 2000-2008. The estimated results of a nested random-effects model showed that hospitals attempted to increase their medical benefit claims under the influence of initial implementation of global budgeting. The magnitudes of hospitals' responses to global budgeting were significantly attributed to hospital ownership, accreditation status, and market competitiveness of a region. The results imply that the regional budget cap superimposed on FFS payments provides only blunt incentive to the hospitals to cooperate to contain medical resource utilization, unless a monitoring mechanism attached with the payment system.

  10. Chemical characterisation of african dust transported to Canary Region

    NASA Astrophysics Data System (ADS)

    Gelado, M. D.; López, P.; Prieto, S.; Collado, C.; Hernández, J. J.

    2009-04-01

    African dust pulses have important effects on the climate conditions and the marine biogeochemistry in the Canary Region. Aerosol samples have been collected at three stations on Gran Canaria Island (Taliarte at sea level, Tafira 269 m a.s.l. and Pico de la Gorra 1930 m a.s.l.) during 2000-2008. Elemental characterisation of the collected mineral aerosol and back trajectories of the air masses are used to distinguish regional African sources of dust. Dust aerosol samples from North Sahara (Morocco, North Algeria and Tunisia), West and Central Sahara (20°-30°N, 18°W-50°E) and Sahel (0°-20°N, 18°W-50°E) have shown different Ca/Ti, Al/Ti and Fe/Al ratios. Ti appears as a better tracer element of specific source of dust than Fe, probably due to a less mineral alteration during the atmospheric transport.

  11. FELINE IMMUNODEFICIENCY VIRUS (FIV) IN WILD PALLAS’ CATS

    PubMed Central

    Brown, Meredith A.; Munkhtsog, Bariushaa; Troyer, Jennifer L.; Ross, Steve; Sellers, Rani; Fine, Amanda E.; Swanson, William F.; Roelke, Melody E.; O’Brien1, Stephen J.

    2009-01-01

    Feline immunodeficiency virus (FIV), a feline lentivirus related to HIV, causes immune dysfunction in domestic and wild cats. The Pallas’ cat is the only species from Asia known to harbor a species-specific strain of FIV designated FIVOma in natural populations. Here, a 25% seroprevalence of FIV is reported from 28 wild Mongolian Pallas’ cats sampled from 2000-2008. Phylogenetic analysis of proviral RT-Pol from eight FIVOma isolates from Mongolia, Russia, China and Kazakhstan reveals a unique monophyletic lineage of the virus within the Pallas’ cat population, most closely related to the African cheetah and leopard FIV strains. Histopathological examination of lymph node and spleen from infected and uninfected Pallas’ cats suggests that FIVOma causes immune depletion in its’ native host. PMID:19926144

  12. Public and private health insurance premiums: how do they affect the health insurance status of low-income childless adults?

    PubMed

    Guy, Gery P; Adams, E Kathleen; Atherly, Adam

    2012-01-01

    The Patient Protection and Affordable Care Act (ACA) will substantially increase public health insurance eligibility and alter the costs of insurance coverage. Using Current Population Survey (CPS) data from the period 2000-2008, we examine the effects of public and private health insurance premiums on the insurance status of low-income childless adults, a population substantially affected by the ACA. Results show higher public premiums to be associated with a decrease in the probability of having public insurance and an increase in the probability of being uninsured, while increased private premiums decrease the probability of having private insurance. Eligibility for premium assistance programs and increased subsidy levels are associated with lower rates of uninsurance. The magnitudes of the effects are quite modest and provide important implications for insurance expansions for childless adults under the ACA.

  13. Urban social and built environments and trajectories of decline in social engagement in vulnerable elders: findings from Detroit's Medicaid home and community-based waiver population.

    PubMed

    Kim, MinHee; Clarke, Philippa

    2015-05-01

    There is little knowledge on the relationships between neighborhood environments and trajectories of social engagement among physically and economically vulnerable older adults. We examined the association between neighborhood social and built environments (physical disorder, the presence of crime watch signs, and street conditions) and 36-month trajectories of social engagement among 965 older adults living in Detroit, Michigan. Social withdrawal was defined as a decline in social engagement without distress while social isolation was defined as a decline in social engagement with distress. We utilized data from Michigan's Minimum Data Set for Home Care (2000-2008), merged with contextual data collected through a virtual audit instrument using Google Earth's "Street View" feature. Results from multilevel multinomial analyses indicated that the presence of neighborhood watch signs was associated with increased chance of social withdrawal and social isolation among frail older adults over time, highlighting the potential anxiety-provoking effect of precautionary measures against crime. © The Author(s) 2014.

  14. IMF By effects in the plasma flow at the polar cap boundary

    NASA Astrophysics Data System (ADS)

    Kozlovsky, Alexander; Lukianova, Renata

    2010-05-01

    We used the dataset obtained from the EISCAT Svalbard Radar during 2000-2008 to study statistically the ionospheric convection as related to IMF By conditions, separately for northward and southward IMF. The effects of IMF By are manifested in the intensity and direction of the East-West component of ionospheric flow. The most significant effects are observed near noon and also in the early morning around 03 MLT, whereas in the evening (at 18 MLT) the effect is essentially less prominent. The other feature is an anti-sunward flow across the polar cap, which shows increasing with the magnitude of IMF By. Quantitative characteristics of the IMF By effects are presented and explained in frame of the magnetospheric electric fields generated due to the solar wind, with taking into account position of the open-closed boundary for different IMF conditions. This work was supported by the Academy of Finland.

  15. Increases in Condomless Sex in the Swiss HIV Cohort Study.

    PubMed

    Kouyos, Roger D; Hasse, Barbara; Calmy, Alexandra; Cavassini, Matthias; Furrer, Hansjakob; Stöckle, Marcel; Vernazza, Pietro L; Bernasconi, Enos; Weber, Rainer; Günthard, Huldrych F; Aubert, V; Battegay, M; Bernasconi, E; Böni, J; Bucher, H C; Burton-Jeangros, C; Calmy, A; Cavassini, M; Dollenmaier, G; Egger, M; Elzi, L; Fehr, J; Fellay, J; Furrer, H; Fux, C A; Gorgievski, M; Günthard, H; Haerry, D; Hasse, B; Hirsch, H H; Hoffmann, M; Hösli, I; Kahlert, C; Kaiser, L; Keiser, O; Klimkait, T; Kouyos, R; Kovari, H; Ledergerber, B; Martinetti, G; de Tejada, B Martinez; Metzner, K; Müller, N; Nadal, D; Nicca, D; Pantaleo, G; Rauch, A; Regenass, S; Rickenbach, M; Rudin, C; Schöni-Affolter, F; Schmid, P; Schüpbach, J; Speck, R; Tarr, P; Trkola, A; Vernazza, P; Weber, R; Yerly, S

    2015-04-01

    Condomless sex is a key driver of sexually transmitted diseases. In this study, we assess the long-term changes (2000-2013) of the occurrence of condomless sex among human immunodeficiency virus (HIV)-infected individuals enrolled in the Swiss HIV Cohort study. The frequencies with which HIV-infected individuals reported condomless sex were either stable or only weakly increasing for 2000-2008. For 2008-2013, these rates increased significantly for stable relationships among heterosexuals and men who have sex with men (MSM) and for occasional relationships among MSM. Our results highlight the increasing public health challenge posed by condomless sex and show that condomless sex has been increasing even in the most recent years.

  16. Crew on the ISS: Creativity or determinism?

    NASA Astrophysics Data System (ADS)

    Krikalev, Sergey K.; Kalery, Alexander Yu.; Sorokin, Igor V.

    2010-01-01

    Analyzing the experience of human flights to the Mir space station in 1986-2000 and to the ISS in 2000-2008, as well as Space Shuttle missions we can define structural and organizational tendencies in human missions to space and mission support. The tendency to the increased determinism in flight operations leads to lower flexibility of the "Crew-Mission Control Center" link in case of contingency. We justify the necessity to reduce the centralization of the control process and to hand over some mission control centers (MCC) authority to the International Space Station (ISS) crew. We conclude that human missions to the Moon and Mars where crew actions will be independent to a high degree will be impossible without resolution of this issue. Creativity and determinism should be properly balanced.

  17. [Hepatolithiasis--a rare disorder in our population].

    PubMed

    Treska, V; Skalický, T; Sutnar, A; Kuntscherová, J

    2009-03-01

    The authors describe diagnostic and therapeutic options of hepatolithiasis, which is a rare disorder in our population. The authors present 3 case--reviews of patients operated for hepatolithiasis in the Plzen Faculty Hospital Surgical Clinic during 2000-2008. In a single subject, the finding was related to a Caroli syndrome. All subjects suffered from symptomatic hepatolithiases (abdominal pains, cholangiogenic sepsis), which was complicated by advanced liver cirrhosis in one case. The diagnostic measures included ultrasonography, computer tomography, MRI cholangiography and endoscopic retrograde cholangiography. In all the subjects, left-sided lobectomy was performed for findings located in the liver segments 2 and 3. The 30-day postoperative mortality was nil. In a single female patient, liver resection (segment 4) was performed for segmental bile duct dilation, bile fistule and chilangiogenic sepsis. Resection of the affected liver region is the method of choice in the management of hepatolithiasis.

  18. Longitudinal Relationships Between Productive Activities and Functional Health in Later Years: A Multivariate Latent Growth Curve Modeling Approach.

    PubMed

    Choi, Eunhee; Tang, Fengyan; Kim, Sung-Geun; Turk, Phillip

    2016-10-01

    This study examined the longitudinal relationships between functional health in later years and three types of productive activities: volunteering, full-time, and part-time work. Using the data from five waves (2000-2008) of the Health and Retirement Study, we applied multivariate latent growth curve modeling to examine the longitudinal relationships among individuals 50 or over. Functional health was measured by limitations in activities of daily living. Individuals who volunteered, worked either full time or part time exhibited a slower decline in functional health than nonparticipants. Significant associations were also found between initial functional health and longitudinal changes in productive activity participation. This study provides additional support for the benefits of productive activities later in life; engagement in volunteering and employment are indeed associated with better functional health in middle and old age. © The Author(s) 2016.

  19. Analysis of maternal and abortion-related mortality in Mexico over the last two decades, 1990-2008.

    PubMed

    Schiavon, Raffaela; Troncoso, Erika; Polo, Gerardo

    2012-09-01

    To document the relative contribution of abortion-related deaths to overall maternal deaths in Mexico, official mortality data were analyzed according to International Classification of Diseases (ICD) codes. During 1990-2008, among 24 805 maternal deaths, 1786 (7.2%) were abortion related. Of these, 13.2% occurred in adolescents and 65% in uninsured women; 60% were probably associated with unsafely induced procedures. The study calculated the number of abortion-related deaths per 100,000 abortion-related hospitalizations, expressed as a modified abortion case-fatality rate. During 2000-2008, this rate was 48 at the national level, with wide variations among states: from 140 deaths in Guerrero to 8 in Baja California Sur per 100,000 abortion hospitalizations. Unsafe abortion continues to represent a significant proportion of all maternal deaths in Mexico. Copyright © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  20. Treatment of Liver Trauma: Operative or Conservative Management

    PubMed Central

    Bernardo, Carmen Garcia; Fuster, Josep; Bombuy, Ernest; Sanchez, Santiago; Ferrer, Joana; Loera, Marco Antonio; Marti, Josep; Fondevila, Constantino; Zavala, Elizabet; Garcia-Valdecasas, Juan Carlos

    2010-01-01

    Background The liver is one of the most frequently damaged organs when abdominal trauma occurs. Currently, a conservative management constitutes the treatment of choice in patients with hemodynamic stability. The aim of this study is to evaluate the results of an operative and conservative management of 143 patients with liver injury treated in a single institution. Methods A retrospective study of the patients admitted with the diagnosis of liver trauma was performed from 1992-2008. The patients were classified according to the intention to treatment: Group I, operative management; Group II, conservative management. Variables analyzed included demographic data, injury classification, associated lesions, surgical treatment, transfusions, morbi-mortality, and hospital stay. We established two periods (1992-1999; 2000-2008) in order to compare diagnosis and management. Results A total of 143 patients were analyzed. Thirty-one percent correspond to severe injuries. Conservative treatment was followed in 60.8 % with surgery undertaken in 14.9 % of patients from this group due to failure of conservative treatment. Immediate surgery was carried out in 38.2 %. Total mortality was 14 %. Morbidity (35.7-38.5 %) in the group of immediate surgery and failure of conservative management is similar, but not in mortality (28.6-15.4 %). In the second group (2000-2008) there are more patients with conservative treatment, with a low percentage of failure of this treatment and morbi-mortality. Conclusions Conservative treatment is an adequate treatment in a great number of patients. Failure of conservative treatment did not show a higher incidence of complications or mortality but it should be performed in centers with experienced surgeons. PMID:27956979

  1. Predictors of persistent villous atrophy in coeliac disease: a population-based study.

    PubMed

    Lebwohl, B; Murray, J A; Rubio-Tapia, A; Green, P H R; Ludvigsson, J F

    2014-03-01

    Villous atrophy (VA) with intraepithelial lymphocytosis is the histological hallmark of coeliac disease (CD), but reported rates of mucosal recovery are variable. To determine the impact of age and other demographic variables on the probability of persistent VA on follow-up biopsy. We identified patients with VA on duodenal histology at all 28 Swedish pathology departments during the years spanning 1969-2008. We examined age, gender, calendar period, duration of disease and educational attainment to determine predictors of persistent VA. Of 7648 patients with CD who underwent follow-up biopsy, persistent VA was present in 3317 (43%; 95% CI 42-44%). The effect of age on persistent VA varied according to time period; among those biopsied in the years spanning 2000-2008, the prevalence of persistent VA was 31%, and increasing age was associated with increasing rates of persistent VA (17% among those younger than 2 years compared to 56% among those ≥70 years). In contrast, persistent VA did not vary widely by age in earlier years. On multivariate analysis (restricted to the calendar period 2000-2008, 2-5 years after CD diagnosis), persistent VA was more common among males (OR 1.43; 95% CI 1.07-1.90) and less common among patients with higher educational attainment (OR for college degree vs. <2 years of high school 0.52, 95% CI 0.35-0.78). The prevalence of persistent villous atrophy has changed over time, with greater rates of healing in recent years. Social differences in persistent villous atrophy suggest that access and/or education regarding the gluten-free diet impact mucosal healing. © 2014 John Wiley & Sons Ltd.

  2. Persistent spatial clusters of plasmacytosis among Danish mink farms.

    PubMed

    Themudo, Gonçalo Espregueira; Østergaard, Jørgen; Ersbøll, Annette Kjær

    2011-10-01

    Aleutian disease (Plasmacytosis) is caused by the Aleutian mink disease virus (AMDV), an autonomous parvovirus and affects many mustelid species, including the American mink (Neovisonvison). In Denmark, an eradication program reduced the prevalence of test-positive farms from 100% in 1976 to 15% in 1996. Nevertheless, the disease persists in the Vendsyssel district of Northern Jutland, despite the eradication efforts. In this study, we used spatial epidemiological analysis to test for spatial autocorrelation of the distribution of farms positive for the disease. We investigated 2375 farms in Denmark (342 of which were located in the Vendsyssel district), during the period 2000-2008. For the purpose of our study, a farm was considered positive when, on any test conducted in a year, at least three animals were tested positive. To detect spatial clusters, we performed a retrospective analysis with spatial scan statistics. We performed one analysis for each of the nine years (2000-2008). A separate analysis was conducted with only the farms in Vendsyssel included. The spatial cluster analysis revealed a significant cluster throughout the time period studied in Northern Jutland. The only exception was 2002 when an outbreak was detected in the southern part of Jutland, and not in the north. The farm-level prevalence of the disease in Denmark was highest in this year, suggesting that the outbreak in the south could have masked the persistent signal from the north; the northern cluster was still significant when analysing only the Vendsyssel populations. These results confirm that Northern Jutland continues to have a significantly higher number of cases than expected if the disease was randomly distributed. Copyright © 2011 Elsevier B.V. All rights reserved.

  3. National Labor Administration and Democracy in Argentina

    DTIC Science & Technology

    1987-08-01

    algunas experiencias Latinoanericanas," Estudios CEDES, V. 3, N. 2 (1980); Oszlak, "Notas Criticas para una Teoria de la Burocracia Estatal," Documento...Interpretation of Weber on Bureaucracy." World Politics, V. 31, N. 2 (January, 1979), pp. 195-227. 7 2For a discussion of the "Proceso"’s labor policies and

  4. Entrenamiento con el traje espacial

    NASA Image and Video Library

    Después de 10 paseos espaciales, el astronauta de la NASA Michael López- Alegría sabe bastante de trajes espaciales. En este video, López Alegría comparte su experiencia acerca del uso y el entrena...

  5. Language and Literacy in the Borderlands: Acting upon the World through "Testimonios"

    ERIC Educational Resources Information Center

    Saavedra, Cinthya M.

    2011-01-01

    Saavedra discusses how children in the borderlands can inform our language and literacy practices through the Latin American literary genre known as "testimonio." Drawing from the work of Chicana/Latina feminist pedagogy, I frame my "experiencias" with language and literacy in three different moments in my life. Through these…

  6. Language and Literacy in the Borderlands: Acting upon the World through "Testimonios"

    ERIC Educational Resources Information Center

    Saavedra, Cinthya M.

    2011-01-01

    Saavedra discusses how children in the borderlands can inform our language and literacy practices through the Latin American literary genre known as "testimonio." Drawing from the work of Chicana/Latina feminist pedagogy, I frame my "experiencias" with language and literacy in three different moments in my life. Through these…

  7. Revista Interamericana de Educacion de Adultos, 2003 (Interamerican Review of Adult Education, 2003).

    ERIC Educational Resources Information Center

    Guerra, Alfonso Rangel, Ed.

    2003-01-01

    This journal offers a collection of Spanish-language articles, including: "Educacion a Distancia y Uso de las Tecnologias: Experiencias Desafios y Oportunidades Educativas para Jovenes y Adultos" (Ma. Mercedes Ruiz); "Volver a a Educacion Fundamental? Notas para una Arquelogia de los Mandatos Fundacionales del CREFAL" (Jorge…

  8. Studies to Control Endemic Typhoid Fever in Chile

    DTIC Science & Technology

    1982-01-29

    experiencia que contribuira’ al control- de la fiebre tifoldea en nuestro pals y en el mundo entero . Saluda.-Itentamerite a Uid., iN BUCHI BUC * ARIISTRO DE...Colaborar en la administraci61t de ]a vacuna oral.7 f) Solicitar lista de )as escuelas del A- rea Norte con su direcci6n y el nombre y numero de tel

  9. [Course of congenital malformation incidences and their changes over time in children born in the Czech Republic].

    PubMed

    Sípek, A; Gregor, V; Horáček, J; Sípek, A; Langhammer, P

    2012-10-01

    An analysis of incidences of selected birth defects in the Czech Republic in 2000 - 2008 period. Retrospective epidemiological analysis of birth defects incidences in births and total birth defects incidences (including prenatally diagnosed cases) from the Czech National Birth Defects Register database. Data from the National Birth Defects Register (Institute for Health Information and Statistics) in the Czech Republic in the 2000 - 2008 period were used along with data on prenatally diagnosed defects from particular departments of medical genetics. Sixteen selected defects (anencephaly, spina bifida, encephalocele, congenital hydrocephalus, coarctation of aorta, transposition of great vessels, hypoplastic left heart syndrome, Fallot tetralogy, omphalocele, gastroschisis, diaphragmatic hernia, oesophageal atresia and stenosis, anorectal malformations, Down syndrome, Edwards syndrome and Patau syndrome) were analyzed in detail. There were 119 570 live births (61 326 boys and 58 244 girls) in 2008. In the same period, 4664 live births with a birth defect (under the age of one year) were reported, out of which 2754 boys and 1910 girls. Mean incidence was 390.06 (449.08 in boys and 327.93 in girls) per 10 000 live births. In 1994 - 2006, totally 1 238 398 children were born, out of which more than 42 000 with a birth defect. In the 2000 - 2006 period, absolute numbers of diagnosed live births with birth defect varied between 3600 - 3800 cases per year while in 2007 and 2008 years absolute numbers raised over 4600 cases per year. During 2000 - 2008 period following mean incidences (per 10 000 live births) of selected defects were ascertained (total incidences including prenatal diagnostics in brackets): anencephaly 0 - 0.3 (1.9 - 3.7), spina bifida 0.7 - 2.3 (3.2 - 5.2), encephalocele 0.1 - 0.4 (0.9 - 2.4), congenital hydrocephalus 1.6 - 3.5 (5.3 - 7.0), coarctation of aorta 3.9 - 5.2 (4.8 - 6.1), transposition of great vessels 2.9 - 4.5 (3.2 - 5.0), hypoplastic left

  10. Impacts of land use change and climate variations on annual inflow into the Miyun Reservoir, Beijing, China

    NASA Astrophysics Data System (ADS)

    Zheng, Jiangkun; Sun, Ge; Li, Wenhong; Yu, Xinxiao; Zhang, Chi; Gong, Yuanbo; Tu, Lihua

    2016-04-01

    The Miyun Reservoir, the only surface water source for Beijing city, has experienced water supply decline in recent decades. Previous studies suggest that both land use change and climate contribute to the changes of water supply in this critical watershed. However, the specific causes of the decline in the Miyun Reservoir are debatable under a non-stationary climate in the past 4 decades. The central objective of this study was to quantify the separate and collective contributions of land use change and climate variability to the decreasing inflow into the Miyun Reservoir during 1961-2008. Different from previous studies on this watershed, we used a comprehensive approach to quantify the timing of changes in hydrology and associated environmental variables using the long-term historical hydrometeorology and remote-sensing-based land use records. To effectively quantify the different impacts of the climate variation and land use change on streamflow during different sub-periods, an annual water balance model (AWB), the climate elasticity model (CEM), and a rainfall-runoff model (RRM) were employed to conduct attribution analysis synthetically. We found a significant (p < 0.01) decrease in annual streamflow, a significant positive trend in annual potential evapotranspiration (p < 0.01), and an insignificant (p > 0.1) negative trend in annual precipitation during 1961-2008. We identified two streamflow breakpoints, 1983 and 1999, by the sequential Mann-Kendall test and double-mass curve. Climate variability alone did not explain the decrease in inflow to the Miyun Reservoir. Reduction of water yield was closely related to increase in actual evapotranspiration due to the expansion of forestland and reduction in cropland and grassland, and was likely exacerbated by increased water consumption for domestic and industrial uses in the basin. The contribution to the observed streamflow decline from land use change fell from 64-92 % during 1984-1999 to 36-58 % during 2000-2008

  11. Impacts of land use change and climate variations on annual inflow into Miyun Reservoir, Beijing, China

    NASA Astrophysics Data System (ADS)

    Zheng, J. K.; Sun, G.; Li, W. H.; Yu, X. X.; Zhang, C.; Gong, Y. B.; Tu, L. H.

    2015-08-01

    Miyun reservoir, the only surface water source for Beijing city, has experienced water supply decline in recent decades. Previous studies suggest that both land use change and climate contributes the changes of water supply in this critical watershed. However, the specific causes of the decline in Miyun reservoir are debatable in a non-stationary climate in the past four decades. The central objective of this study was to quantify the separate and collective contributions of land use change and climate variability to the decreasing inflow into Miyun reservoir during 1961-2008. Different from previous studies, this work objectively identified breakpoints by analyzing the long-term historical hydrometeorology and land cover records. To effectively study the different impacts of the climate variation and land cover change during different sub-periods, annual water balance model (AWB), climate elasticity model (CEM), and rainfall-runoff model (RRM) were employed to conduct attribution analysis synthetically. We found a significant decrease in annual streamflow (p < 0.01), a significant positive trend in annual potential evapotranspiration (p < 0.01), and an insignificant negative trend in annual precipitation (p > 0.1) during 1961-2008. Combined with historical records, we identified two breakpoints as in 1983 and 1999 for the period 1961-2008 by the sequential Mann-Kendall Test and Double Mass Curve. Climate variability alone did not explain the decrease in inflow to Miyun reservoir. Reduction of water yield was closely related to increase in evapotranspiration rates due to the expansion of forestlands and reduction in cropland and grassland, and was likely exacerbated by increased water consumption for domestic and industrial uses in the basin. Our study found that the contribution to the observed streamflow decline from land use change fell from 64-92 % during 1984-1999 to 36-58 % during 2000-2008, whereas the contribution from climate variation climbed from 8

  12. X-ray long-term variations in the low-luminosity AGN NGC 835 and its circumnuclear emission

    NASA Astrophysics Data System (ADS)

    González-Martín, O.; Hernández-García, L.; Masegosa, J.; Márquez, I.; Rodríguez-Espinosa, J. M.; Acosta-Pulido, J. A.; Alonso-Herrero, A.; Dultzin, D.; Esparza Arredondo, D.

    2016-03-01

    Context. Obscured active galactic nuclei (AGNs) are thought to be very common in the Universe. Observations and surveys have shown that the number of sources increases for near galaxies and at the low-luminosity regime (the so-called LLAGNs). Furthermore, many AGNs show changes in their obscuration properties at X-rays that may suggest a configuration of clouds very close to the accretion disk. However, these variations could also be due to changes in the intrinsic continuum of the source. It is therefore important to study nearby AGN to better understand the locus and distribution of clouds in the neighbourhood of the nucleus. Aims: We aim to study the nuclear obscuration of LLAGN NGC 835 and its extended emission using mid-infrared observations. Methods: We present sub-arcsecond-resolution mid-infrared 11.5 μm imaging of the LLAGN galaxy NGC 835 obtained with the instrument CanariCam in the Gran Telescopio CANARIAS (GTC), archival Spitzer/IRS spectroscopy, and archival Chandra data observed in 2000, 2008, and 2013. Results: The GTC/CanariCam 11.5 μm image reveals faint extended emission out to ~6 arcsec. We obtained a nuclear flux of F(11.5 μm) ~ 18 mJy, whereas the extended emission accounts for 90% of the total flux within the 6 arcsec. This means that the low angular resolution (~4 arcsec) IRS spectrum is dominated by this extended emission and not by the AGN. This is clearly seen in the Spitzer/IRS spectrum, which resembles that of star-forming galaxies. Although the extended soft X-ray emission shows some resemblance with that of the mid-infrared, the knots seen at X-rays are mostly located in the inner side of this mid-infrared emission. The nuclear X-ray spectrum of the source has undergone a spectral change between 2000/2008 and 2013. We argue that this variation is most probably due to changes in the hydrogen column density from ~8 × 1023 cm-2 to ~3 × 1023 cm-2. NGC 835 therefore is one of the few LLAGN, together with NGC 1052, in which changes in

  13. Clean indoor air regulation and incidence of hospital admissions for acute coronary syndrome in Kanawha County, West Virginia.

    PubMed

    Gupta, Rahul; Luo, Juhua; Anderson, Robert H; Ray, Anita

    2011-07-01

    Secondhand smoke is a risk factor for coronary heart disease. Laws and regulations prohibiting smoking in public areas and workplaces can reduce rates of acute myocardial infarction. Our objective was to describe hospital admission rates for acute coronary events, based on smoking status, diabetes status, and sex, in the presence of a long-standing (2000-2008) county clean indoor air regulation (CIAR). We also examined the effect of making restaurants completely smoke-free. We obtained hospital admission data for acute coronary syndrome (ACS) and acute myocardial infarction from all acute care hospitals serving Kanawha County, West Virginia, for 2000 through 2008. A CIAR was enacted in 1995 and revised in 2000 and 2003. We performed descriptive analyses on hospital admission rates of ACS over time and present these data by sex, age group, smoking status, and medical history of diabetes. The incidence of hospital admissions for ACS consistently declined during the period studied. This change was most pronounced among nonsmokers, people without diabetes, and women, compared with their respective counterparts. Similar benefits occurred for male smokers when the CIAR was revised to make restaurants completely smoke-free in 2004. In the presence of a CIAR, a consistent decline in incidence of hospital admissions for ACS can be demonstrated. However, the benefits derived may be disproportionately affected by smoking status, diabetes status, and sex.

  14. [Spatiotemporal characteristics of MODIS NDVI in Hulunber Grassland].

    PubMed

    Zhang, Hong-Bin; Yang, Gui-Xia; Wu, Wen-Bin; Li, Gang; Chen, Bao-Rui; Xin, Xiao-Ping

    2009-11-01

    Time-series MODIS NDVI datasets from 2000 to 2008 were used to study the spatial change trend, fluctuation degree, and occurrence time of the annual NDVImax of four typical grassland types, i.e., lowland meadow, temperate steppe, temperate meadow steppe, and upland meadow, in Hulunber Grassland. In 2000-2008, the vegetation in Hulunber Grassland presented an obvious deterioration trend. The mean annual NDVImax of the four grassland types had a great fluctuation, especially in temperate steppe where the maximum change in the mean value of annual NDVImax approximated to 50%. As for the area change of different grade grasslands, the areas with NDVImax between 0.4 and 1 accounted for about 91% of the total grassland area, which suggested the good vegetation coverage in the Grassland. However, though the areas with NDVImax values in (0.4, 0.8) showed an increasing trend, the areas with NDVImax values in (0.2, 0.4) and (0.8, 1) decreased greatly in the study period. Overall, the deteriorating grassland took up about 66.25% of the total area, and the restoring grassland took the rest. There was about 62.85% of the grassland whose NDVImax occurred between the 193rd day and the 225th day in each year, indicating that this period was the most important vegetation growth season in Hulunber Grassland.

  15. Influence of atmospheric states in semi-arid areas on hospital admission in cardio-surgical department

    NASA Astrophysics Data System (ADS)

    Yackerson, Naomy S.; Zilberman, Arkadi; Aizenberg, Alexander

    2017-04-01

    The influence of the changes in atmospheric state, typical for areas close to big deserts, on acute myocardial infarction (AMI) was analyzed. Under test was the group of 3256 patients (77 % males, 23 % females), hospitalized in the Cardio-Surgical Department of Soroka Medical Center at Ben-Gurion University (BGU, Israel) during 2000-2008. To explore the relationship between atmospheric parameters and AMI, multivariate regression analysis has been performed. AMI was most frequent in winter to spring and least in summer. The highest number of cases was recorded in December and the lowest in September. Hospital admissions showed a higher prevalence in men than in women; the ratio is 3.3/1.0. About 60 % of males were aged between 45 and 65 years old with maximum ˜55 (21 %), whereas 60 % of women hospital admissions were aged between 65 and 80 years old with maximum ˜72 (24 %). The result suggested that the monthly mean relative humidity at daytime and its overall daily differences, wind speed, and respirable fraction of particulate concentration are associated with the admission for AMI. The results of the study confirm the importance of atmospheric state variability for cardiovascular diseases.

  16. The nature of advocacy vs. paternalism in nursing: clarifying the 'thin line'.

    PubMed

    Zomorodi, Meg; Foley, Barbara Jo

    2009-08-01

    This paper is an exploration of the concepts of advocacy and paternalism in nursing and discusses the thin line between the two. Nurses are involved in care more than any other healthcare professionals and they play a central role in advocating for patients and families. It is difficult to obtain a clear definition of advocacy, yet the concepts of advocacy and paternalism must be compared, contrasted, and discussed extensively. In many situations, only a thin line distinguishes advocacy from paternalism. A literature search was conducted using PubMed and CINAHL databases (2000-2008) as well as a library catalogue for texts. Four case stories were described in order to discuss the 'thin line' between advocacy and paternalism and develop communication strategies to eliminate ambiguity. Weighing the ethical principles of beneficence and autonomy helps to clarify advocacy and paternalism and provides an avenue for discussion among nurses practicing in a variety of settings. Advocacy and paternalism should be discussed at interdisciplinary rounds, and taken into consideration when making patient care decisions. It is difficult to clarify advocacy vs. paternalism, but strategies such as knowing the patient, clarifying information, and educating all involved are initial steps in distinguishing advocacy from paternalism. Truly 'knowing' patients, their life experiences, values, beliefs and wishes can help clarify the 'thin line' and gain a grasp of these difficult to distinguish theoretical concepts.

  17. Influence of atmospheric states in semi-arid areas on hospital admission in cardio-surgical department.

    PubMed

    Yackerson, Naomy S; Zilberman, Arkadi; Aizenberg, Alexander

    2017-04-01

    The influence of the changes in atmospheric state, typical for areas close to big deserts, on acute myocardial infarction (AMI) was analyzed. Under test was the group of 3256 patients (77 % males, 23 % females), hospitalized in the Cardio-Surgical Department of Soroka Medical Center at Ben-Gurion University (BGU, Israel) during 2000-2008. To explore the relationship between atmospheric parameters and AMI, multivariate regression analysis has been performed. AMI was most frequent in winter to spring and least in summer. The highest number of cases was recorded in December and the lowest in September. Hospital admissions showed a higher prevalence in men than in women; the ratio is 3.3/1.0. About 60 % of males were aged between 45 and 65 years old with maximum ∼55 (21 %), whereas 60 % of women hospital admissions were aged between 65 and 80 years old with maximum ∼72 (24 %). The result suggested that the monthly mean relative humidity at daytime and its overall daily differences, wind speed, and respirable fraction of particulate concentration are associated with the admission for AMI. The results of the study confirm the importance of atmospheric state variability for cardiovascular diseases.

  18. A multistudy analysis investigating systematic differences in cardiovascular trial results between Europe and Asia.

    PubMed

    Hartley, Louise C; Girling, Alan J; Bowater, Russell J; Lilford, Richard J

    2015-04-01

    To assess whether there are differences in the results of cardiovascular trials between Europe and Asia using data from an extensive collection of randomised controlled trials. All meta-analyses containing randomised controlled trials (RCT's) for the treatment or prevention of cardiovascular diseases were searched for in The Cochrane Library (2000-2008) and MEDLINE (2005-2008). Analysis was then conducted within and over each meta-analysis which satisfied given criteria. Separate estimates of treatment effect were calculated for Europe and Asia in each meta-analysis and then compared. Estimates of a common inter-continental difference over all meta-analyses were also calculated and meta-regression was performed. This was performed for both fatal and non-fatal end points. The literature search identified 59 meta-analyses that satisfied the inclusion criteria. After exclusion, the number of meta-analyses reporting greater effect sizes in Asia than in Europe was significantly more than would be expected by chance (fatal 12/14, p=0.013; non-fatal 23/32, p=0.020). This study provides some evidence that for cardiovascular interventions treatment effect estimation differs between Europe and Asia, with respect to both fatal and non-fatal end points. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  19. Probing the Long Timescale Evolution of Magnetic Activity of Ultracool Dwarfs

    NASA Astrophysics Data System (ADS)

    Cid, Aurora; Ventura, Jean-Paul; Schmidt, Sarah J.; Rice, Emily L.; Cruz, Kelle L.

    2017-06-01

    The chromospheric variability, as measured by H-alpha emission, of ultracool dwarfs (M7-L3) is still not completely understood. Using spectra from the Sloan Digital Sky Survey (SDSS), we are in the process of measuring equivalent widths of the H-alpha emission lines of ultracool dwarfs over multi-year timescales. More specifically, we are utilizing spectra from Data Release 7, composed of data from 2000-2008, and the Few Epoch Spectroscopy (FES) component of the Time Domain Spectroscopic Survey (TDSS), which is composed of data from 2014-2018. We have 2-3 spectra for 1000 objects and will obtain H-alpha equivalent width measurements over time spans of 6-18 years. By studying the chromospheres of ultracool dwarfs on these timescales, we can make comparisons to the solar magnetic cycle and try to understand the process causing their H-alpha variability. Additionally, we can investigate any relationship between variability and stellar age by combining our measurements with tracers like galactic height and UVW kinematics. We will present preliminary results of this work.

  20. Remotely-sensed active fire data for protected area management: eight-year patterns in the Manas National Park, India.

    PubMed

    Takahata, Chihiro; Amin, Rajan; Sarma, Pranjit; Banerjee, Gitanjali; Oliver, William; Fa, John E

    2010-02-01

    The Terai-Duar savanna and grasslands, which once extended along most of the Himalayan foothills, now only remain in a number of protected areas. Within these localities, grassland burning is a major issue, but data on frequency and distribution of fires are limited. Here, we analysed the incidence of active fires, which only occur during the dry season (Nov.-Mar.), within a significant area of Terai grasslands: the Manas National Park (MNP), India. We obtained locations of 781 fires during the 2000-2008 dry seasons, from the Fire Information for Resource Management System (FIRMS) that delivers global MODIS hotspot/fire locations using remote sensing and GIS technologies. Annual number of fires rose significantly from around 20 at the start of the study period to over 90 after 2002, with most (85%) detected between December and January. Over half of the fires occurred in tall grasslands, but fire density was highest in wetland and riverine vegetation, dry at the time. Most burning took place near rivers, roads and the park boundary, suggesting anthropogenic origins. A kernel density map of all recorded fires indicated three heavily burnt areas in the MNP, all within the tall grasslands. Our study demonstrates, despite some technical caveats linked to fire detection technology, which is improving, that remote fire data can be a practical tool in understanding fire concentration and burning temporal patterns in highly vulnerable habitats, useful in guiding management.

  1. Remotely-Sensed Active Fire Data for Protected Area Management: Eight-Year Patterns in the Manas National Park, India

    NASA Astrophysics Data System (ADS)

    Takahata, Chihiro; Amin, Rajan; Sarma, Pranjit; Banerjee, Gitanjali; Oliver, William; Fa, John E.

    2010-02-01

    The Terai-Duar savanna and grasslands, which once extended along most of the Himalayan foothills, now only remain in a number of protected areas. Within these localities, grassland burning is a major issue, but data on frequency and distribution of fires are limited. Here, we analysed the incidence of active fires, which only occur during the dry season (Nov.-Mar.), within a significant area of Terai grasslands: the Manas National Park (MNP), India. We obtained locations of 781 fires during the 2000-2008 dry seasons, from the Fire Information for Resource Management System (FIRMS) that delivers global MODIS hotspot/fire locations using remote sensing and GIS technologies. Annual number of fires rose significantly from around 20 at the start of the study period to over 90 after 2002, with most (85%) detected between December and January. Over half of the fires occurred in tall grasslands, but fire density was highest in wetland and riverine vegetation, dry at the time. Most burning took place near rivers, roads and the park boundary, suggesting anthropogenic origins. A kernel density map of all recorded fires indicated three heavily burnt areas in the MNP, all within the tall grasslands. Our study demonstrates, despite some technical caveats linked to fire detection technology, which is improving, that remote fire data can be a practical tool in understanding fire concentration and burning temporal patterns in highly vulnerable habitats, useful in guiding management.

  2. Association of 'Candidatus Phytoplasma asteris' with yellowing and phyllody of Plantago lanceolata.

    PubMed

    Fránová, J; Simková, M

    2009-09-01

    Long plantains (Plantago lanceolata L.) with symptoms resembling those associated with phytoplasma infection were observed repeatedly during the period 2000-2008 in southern Bohemia (Czech Republic). The symptoms of the plants were leaf yellowing, stunted growth, flower phyllody and lack of seed production. Transmission electron microscopy showed phytoplasmas in the sieve cells of affected plants but not in healthy ones. Association of phytoplasmas with the disease was confirmed by polymerase chain reaction using phytoplasma-specific universal ribosomal primers R16F2n/R16R2. An amplification product of the expected size (1.2 kb) was observed in all samples of the symptomatic long plantains. The restriction profiles obtained from digestion of the PCR products with three endonucleases (AluI, HhaI, MseI) showed that the phytoplasmas infecting long plantains in the Czech Republic were indistinguishable from those belonging to the aster yellows group (subgroup 16SrI-B). Sequence analysis of 1748 bp of the ribosomal operon indicated that the closest related phytoplasma was that associated with 'Rehmannia glutinosa var. purpurea', originating also in Bohemia. This is the first report of the natural occurrence of 'Candidatus Phytoplasma asteris' in plants of P. lanceolata.

  3. Review of the Medical Research Ethics Committee (MREC), National Research Center of Egypt, 2003-2011.

    PubMed

    Abdel-Aal, Wafaa; Ghaffar, Esmat Abdel; El Shabrawy, Osama

    2013-10-01

    Globally, ethical issues in research are becoming of major importance, being well established in developed countries with little information about research ethics committees (RECs) in Africa to assess whether these committees are actually improving the protection of human research participants. To describe the establishment, structure, function, operations and outcome of the Medical Research Ethics Committee (MREC) of the National Research Center (NRC) of Egypt from 2003 to 2011. The committee established its regulatory rules for human and animal research ethics based on the Declaration of Helsinki 2000-2008 and WHO regulations 2000-2011. There were 974 protocols revised in the 7 years (2005-2011). The outcome of the committee discussions was to clear 262 of the protocols without conditions. A full 556 were cleared conditionally upon completion of modifications. Another 118 were deferred pending action and further consideration at a subsequent meeting. And 16 researchers did not reply, while 22 protocols were rejected. Since 2005, the MREC in NRC Egypt has built up considerable experience of evaluating the ethical issues arising within the field of medical research.

  4. Redotex ingestions reported to Texas poison centers.

    PubMed

    Forrester, Mathias B

    2010-09-01

    Although the multi-component weight loss supplement Redotex is banned in the United States, the supplement can be obtained in Mexico. The intent of this report was to describe the pattern of Redotex calls received by a statewide poison center system. Cases were all Redotex calls received by Texas poison centers during 2000-2008. The distribution of total calls and those involving ingestion of the supplement were determined for selected demographic and clinical factors. Of 34 total Redotex calls received, 55.9% came from the 14 Texas counties that border Mexico. Of the 22 reported Redotex ingestions, 77.3% of the patients were female and 45.5% 20 years or more. Of the 17 ingestions involving no co-ingestants, 52.9% were already at or en route to a health care facility, 41.2% were managed on site, and 5.9% was referred to a health care facility. The final medical outcome was no effect in 23.5% cases, minor effect in 5.9%, moderate effect in 11.8%, not followed but minimal clinical effects possible in 47.1%, and unable to follow but judged to be potentially toxic in 11.8%. Most Redotex calls to the Texas poison center system originated from counties bordering Mexico.

  5. Clusters of adolescent and young adult thyroid cancer in Florida counties.

    PubMed

    Amin, Raid; Burns, James J

    2014-01-01

    Thyroid cancer is a common cancer in adolescents and young adults ranking 4th in frequency. Thyroid cancer has captured the interest of epidemiologists because of its strong association to environmental factors. The goal of this study is to identify thyroid cancer clusters in Florida for the period 2000-2008. This will guide further discovery of potential risk factors within areas of the cluster compared to areas not in cluster. Thyroid cancer cases for ages 15-39 were obtained from the Florida Cancer Data System. Next, using the purely spatial Poisson analysis function in SaTScan, the geographic distribution of thyroid cancer cases by county was assessed for clusters. The reference population was obtained from the Census Bureau 2010, which enabled controlling for population age, sex, and race. Two statistically significant clusters of thyroid cancer clusters were found in Florida: one in southern Florida (SF) (relative risk of 1.26; P value of <0.001) and the other in northwestern Florida (NWF) (relative risk of 1.71; P value of 0.012). These clusters persisted after controlling for demographics including sex, age, race. In summary, we found evidence of thyroid cancer clustering in South Florida and North West Florida for adolescents and young adult.

  6. How ecological restoration alters ecosystem services: an analysis of carbon sequestration in China's Loess Plateau.

    PubMed

    Feng, Xiaoming; Fu, Bojie; Lu, Nan; Zeng, Yuan; Wu, Bingfang

    2013-10-03

    Restoring disturbed and over-exploited ecosystems is important to mitigate human pressures on natural ecosystems. China has launched an ambitious national ecosystem restoration program called Grain to Green Program (GTGP) over the last decade. By using remote sensing techniques and ecosystem modelling, we quantitatively evaluated the changes in ecosystem carbon sequestration since China's GTGP program during period of 2000-2008. It was found the NPP and NEP in this region had steadily increased after the initiative of the GTGP program, and a total of 96.1 Tg of additional carbon had been sequestered during that period. Changes in soil carbon storage were lagged behind and thus insignificant over the period, but was expected to follow in the coming decades. As a result, the Loess Plateau ecosystem had shifted from a net carbon source in 2000 to a net carbon sink in 2008. The carbon sequestration efficiency was constrained by precipitation, and appropriate choices of restoration types (trees, shrubs, and grasses) in accordance to local climate are critical for achieving the best benefit/cost efficiency.

  7. Biliary strictures and hepatic artery flow abnormalities in split liver transplants.

    PubMed

    O'Loughlin, Edward V; Stormon, Michael O; Shun, Albert; Verran, Deborah; Jermyn, Vicki; Wong, Christopher; Lord, David

    2010-02-01

    The aim of this study was to examine the role of HA flow abnormalities in the development of biliary strictures following split liver transplants. Data was obtained from a prospective data base of all patients undergoing split liver transplants from 2000-2008 with a follow up time of at least six months. Forty-six transplants were performed in 44 patients. Fourteen of 46 developed strictures of whom four were intrahepatic and 10 anastomotic. Nine of 14 with strictures had either hepatic artery thromobosis (HAT, four) or abnormalities of HA flow identified by routine Doppler ultrasound (5) compared with two of 32 without strictures (p < 0.02, (one temporary loss of flow and one HA aneurysm). There were no differences between the stricture and non stricture group with regard to age or weight at transplant, donor age, cold and warm ischemia times or intraoperative portal vein flow though there was a significant decrease in intraoperative HA flow in the stricture group. In conclusion, both HAT and hepatic artery flow abnormalities are associated with biliary strictures in the majority of split liver transplants. However, unrecognised abnormalities in HA flow and or other factors are likely to contribute.

  8. Knowledge mobilisation in healthcare: a critical review of health sector and generic management literature.

    PubMed

    Ferlie, Ewan; Crilly, Tessa; Jashapara, Ashok; Peckham, Anna

    2012-04-01

    The health policy domain has displayed increasing interest in questions of knowledge management and knowledge mobilisation within healthcare organisations. We analyse here the findings of a critical review of generic management and health-related literatures, covering the period 2000-2008. Using 29 pre-selected journals, supplemented by a search of selected electronic databases, we map twelve substantive domains classified into four broad groups: taxonomic and philosophical (e.g. different types of knowledge); theoretical discourse (e.g. critical organisational studies); disciplinary fields (e.g. organisational learning and Information Systems/Information Technology); and organisational processes and structures (e.g. organisational form). We explore cross-overs and gaps between these traditionally separate literature streams. We found that health sector literature has absorbed some generic concepts, notably Communities of Practice, but has not yet deployed the performance-oriented perspective of the Resource Based View (RBV) of the Firm. The generic literature uses healthcare sites to develop critical analyses of power and control in knowledge management, rooted in neo-Marxist/labour process and Foucauldian approaches. The review generates three theoretically grounded statements to inform future enquiry, by: (a) importing the RBV stream; (b) developing the critical organisational studies perspective further; and (c) exploring the theoretical argument that networks and other alternative organisational forms facilitate knowledge sharing.

  9. Prevalence of hearing loss in the United States by industry.

    PubMed

    Masterson, Elizabeth A; Tak, SangWoo; Themann, Christa L; Wall, David K; Groenewold, Matthew R; Deddens, James A; Calvert, Geoffrey M

    2013-06-01

    Twenty-two million workers are exposed to hazardous noise in the United States. The purpose of this study is to estimate the prevalence of hearing loss among U.S. industries. We examined 2000-2008 audiograms for male and female workers ages 18-65, who had higher occupational noise exposures than the general population. Prevalence and adjusted prevalence ratios (PRs) for hearing loss were estimated and compared across industries. In our sample, 18% of workers had hearing loss. When compared with the Couriers and Messengers industry sub-sector, workers employed in Mining (PR = 1.65, CI = 1.57-1.73), Wood Product Manufacturing (PR = 1.65, CL = 1.61-1.70), Construction of Buildings (PR = 1.52, CI = 1.45-1.59), and Real Estate and Rental and Leasing (PR = 1.61, CL = 1.51-1.71) [corrected] had higher risks for hearing loss. Workers in the Mining, Manufacturing, and Construction industries need better engineering controls for noise and stronger hearing conservation strategies. More hearing loss research is also needed within traditional "low-risk" industries like Real Estate. Copyright © 2012 Wiley Periodicals, Inc.

  10. The state and the development of an information society: Greek policy and experience.

    PubMed

    Boucas, Dimitris

    2017-09-01

    The paper looks into the dynamics of information society policy and its implementation in the Greek context. It argues that information society development is a contested process, influenced by pre-existing state, economy and society relations. Based on this, it looks into the different aspects of the idiosyncratic path which the evolution of the Greek information society has followed, particularly after 2000. Using Bob Jessop's strategic-relational approach (SRA) to the state as an analytical framework and drawing on a number of in-depth interviews with relevant political actors, it provides insights into policy implementation by examining: the public management of information technology projects, how such projects were received in bureaucratic structures and practices, as well as the relationship between the state and the information and communication technology (ICT) sector in public procurement processes. The emphasis is on the period 2000-2008, during which a major operational programme on the information society in Greece was put into effect. The paper also touches upon the post-2008 experience, suggesting that information society developments might include dynamics operating independently and even in contradiction to the state agenda. © London School of Economics and Political Science 2017.

  11. Negotiation strategies and patient empowerment in Spanish and British medical consultations.

    PubMed

    Hernández-López, María de la O

    2011-01-01

    Making a decision is not only one of the physician's most important responsibilities but also one of patients' most sensitive moments in medical encounters. Drawing from pragmatics studies, this paper explores rapport maintenance and/or enhancement (Spencer-Oatey 2000, 2008) in the decision-making strategies that General Practitioners (GPs) and patients employ in 80 encounters in various areas of England and Spain. The results show that such strategies are context-bound and subject to role specifications: while patients may make use of (dis)agreement strategies and initiate decisions and/or self-diagnosis, doctors give options, show empathy, expand explanations or show explicit or implicit (dis) agreement. In relation to this, notable findings were revealed: first, these communicative strategies may vary not only in terms of frequency but also quality and distribution; second, the Spanish interlocutors in the data gathered tend to negotiate through the explicit expression of opinions, while the British interlocutors prefer the discussion of different alternatives and value the other's freedom to act. Third, there is higher tolerance of disagreement in the Spanish data. Fourth, negotiation may be undertaken on the basis of either self-affirmation or consensus-seeking beliefs. Finally, patient empowerment is displayed in divergent ways in both sets of data. In short, the decision-making processes examined are subject to social and psychological factors with a direct impact on communicative styles.

  12. Monitoring programme on nitrates in vegetables and vegetable-based baby foods marketed in the Region of Valencia, Spain: levels and estimated daily intake.

    PubMed

    Pardo-Marín, O; Yusà-Pelechà, V; Villalba-Martín, P; Perez-Dasí, J A

    2010-04-01

    This study was carried out to determine the current levels of nitrates in vegetables and vegetable-based baby foods (a total of 1150 samples) marketed in the Region of Valencia, Spain, over the period 2000-2008, and to estimate the toxicological risk associated with their intake. Average (median) levels of nitrate in lettuce, iceberg-type lettuce and spinach (1156, 798 and 1410 mg kg(-1) w/w, respectively) were lower than the maximum limits established by European Union legislation. Thirteen fresh spinach samples exceeded the regulatory limits. Median nitrate values in other vegetables for which a maximum limit has not been fixed by the European Commission were 196, 203, 1597, 96, 4474 and 2572 mg kg(-1) w/w (for potato, carrot, chard, artichoke, rucola and lamb's lettuce, respectively). The estimated nitrate daily intakes through vegetables consumption for adult, extreme consumers and children were found to be about 29%, 79.8% and 15.1%, respectively, of the acceptable daily intake (3.7 mg kg(-1)). The levels (median = 60.4 mg kg(-1) w/w) found in vegetable-based baby foods were, in all cases, lower the maximum level proposed by European Union legislation. The estimated nitrate daily intake through baby foods for infants between 0-1 and 1-2 years of age were 13% and 18%, respectively, of the acceptable daily intake.

  13. Where does public funding for HIV prevention go to? The case of condoms versus microbicides and vaccines

    PubMed Central

    2010-01-01

    This study analyses the priorities of public donors in funding HIV prevention by either integrated condom programming or HIV preventive microbicides and vaccines in the period between 2000 and 2008. It further compares the public funding investments of the USA government and European governments, including the EU, as we expect the two groups to invest differently in HIV prevention options, because their policies on sexual and reproductive health and rights are different. We use two existing officially UN endorsed databases to compare the public donor funding streams for HIV prevention of these two distinct contributors. In the period 2000-2008, the relative share of public funding for integrated condom programming dropped significantly, while that for research on vaccines and microbicides increased. The European public donors gave a larger share to condom programming than the United States, but exhibited a similar downward trend in favour of funding research on vaccines and microbicides. Both public donor parties invested progressively more in research on vaccines and microbicides rather than addressing the shortage of condoms and improving access to integrated condom programming in developing countries. PMID:21192787

  14. Trends and Disparities in TB among U.S. Born Black and White Chicago Residents, 1998 - 2008

    PubMed Central

    Lippold, Susan A.; Carter, Jennifer M.; Armstrong, Lori; Hardison, Xiomara

    2017-01-01

    Objective To describe the decline of tuberculosis (TB) cases among U.S.-born non-Hispanic (NH) black and white Chicago residents. Methods Data from the National TB Surveillance System was used to analyze trends and characteristics of reported TB cases among U.S.-born NH black and U.S.-born NH white Chicago residents from 1998-2008. Results Chicago reported a total of 3,821 TB cases over the 11-year time period. Of these, 1,916 were U.S.-born NH black and 235 were U.S.-born NH white. The proportion of cases attributable to U.S.-born NH blacks was 63% (294/469) in 1998 and 34% in 2008 (72/213). Regression analysis for trends from 2000-2008 revealed a greater than predicted decrease in rates among U.S.-born NH blacks (p<0.05). U.S.-born NH blacks had greater odds than U.S.-born NH whites of HIV infection (OR 1.8), non-injecting drug use (OR 3.0), unemployment (OR 1.7), receiving care from the health department (OR 2.2) and receiving directly observed therapy (OR 3.0). Conclusion Despite more TB risk factors in Chicago’s U.S.-born black population, there was a narrowing of TB case disparity in Chicago from 1998-2008. Continued focused strategies aimed at controlling TB are needed. PMID:28845366

  15. Increase in newly diagnosed HIV infections among young black men who have sex with men--Milwaukee County, Wisconsin, 1999-2008.

    PubMed

    2011-02-04

    During 2001-2006, new human immunodeficiency virus (HIV) diagnoses among black men aged 13-24 years who have sex with men (MSM) in 33 states increased by 93%. The Wisconsin Division of Public Health (WDPH) recently reported to CDC a 144% increase during 2000-2008 in HIV diagnoses among black MSM aged 15-29 years in Milwaukee County. In October 2009, the City of Milwaukee Health Department (MHD), WDPH, and CDC investigated whether the increase in HIV infections among young black MSM in Milwaukee represented increased HIV transmission or simply better identification of prevalent infections. This report describes the results of that investigation, which indicated that a new "social networks" HIV testing strategy and the recent expansion of better targeted HIV testing efforts accounted for few diagnoses among young black MSM and occurred after HIV diagnoses increased, respectively. Therefore, although some diagnoses were made because of intensified testing, an increase in HIV transmission likely occurred. Moreover, an increase in syphilis diagnoses among young black MSM in Milwaukee preceded the increase in HIV diagnoses, which suggests that changes in risk behavior or sexual networks might explain the increase. These findings highlight the need for new or improved interventions promoting prevention education, early HIV detection, and entry to care for young HIV-infected and at-risk black MSM in Milwaukee.

  16. The Impact of Hurricane Katrina on Students' Behavioral Disorder: A Difference-in-Difference Analysis.

    PubMed

    Tian, Xian-Liang; Guan, Xian

    2015-05-22

    The objective of this paper is to examine the impact of Hurricane Katrina on displaced students' behavioral disorder. First, we determine displaced students' likelihood of discipline infraction each year relative to non-evacuees using all K12 student records of the U.S. state of Louisiana during the period of 2000-2008. Second, we investigate the impact of hurricane on evacuee students' in-school behavior in a difference-in-difference framework. The quasi-experimental nature of the hurricane makes this framework appropriate with the advantage that the problem of endogeneity is of least concern and the causal effect of interest can be reasonably identified. Preliminary analysis demonstrates a sharp increase in displaced students' relative likelihood of discipline infraction around 2005 when the hurricane occurred. Further, formal difference-in-difference analysis confirms the results. To be specific, post Katrina, displaced students' relative likelihood of any discipline infraction has increased by 7.3% whereas the increase in the relative likelihood for status offense, offense against person, offense against property and serious crime is 4%, 1.5%, 3.8% and 2.1%, respectively. When disasters occur, as was the case with Hurricane Katrina, in addition to assistance for adult evacuees, governments, in cooperation with schools, should also provide aid and assistance to displaced children to support their mental health and in-school behavior.

  17. Recent Rates of Forest Harvest and Conversion in North America

    NASA Technical Reports Server (NTRS)

    Masek, Jeffrey G.; Cohen, Warren B.; Leckie, Donald; Wulder, Michael A.; Vargas, Rodrigo; de Jong, Ben; Healey, Sean; Law, Beverly; Birdsey, Richard; Houghton, R. A.; Mildrexler, David; Goward, Samuel; Smith, W. Brad

    2011-01-01

    Incorporating ecological disturbance into biogeochemical models is critical for estimating current and future carbon stocks and fluxes. In particular, anthropogenic disturbances, such as forest conversion and wood harvest, strongly affect forest carbon dynamics within North America. This paper summarizes recent (2000.2008) rates of extraction, including both conversion and harvest, derived from national forest inventories for North America (the United States, Canada, and Mexico). During the 2000s, 6.1 million ha/yr were affected by harvest, another 1.0 million ha/yr were converted to other land uses through gross deforestation, and 0.4 million ha/yr were degraded. Thus about 1.0% of North America fs forests experienced some form of anthropogenic disturbance each year. However, due to harvest recovery, afforestation, and reforestation, the total forest area on the continent has been roughly stable during the decade. On average, about 110 m3 of roundwood volume was extracted per hectare harvested across the continent. Patterns of extraction vary among the three countries, with U.S. and Canadian activity dominated by partial and clear ]cut harvest, respectively, and activity in Mexico dominated by conversion (deforestation) for agriculture. Temporal trends in harvest and clearing may be affected by economic variables, technology, and forest policy decisions. While overall rates of extraction appear fairly stable in all three countries since the 1980s, harvest within the United States has shifted toward the southern United States and away from the Pacific Northwest.

  18. Agricultural non-point source pollution in China: causes and mitigation measures.

    PubMed

    Sun, Bo; Zhang, Linxiu; Yang, Linzhang; Zhang, Fusuo; Norse, David; Zhu, Zhaoliang

    2012-06-01

    Non-point source (NPS) pollution has been increasingly serious in China since the 1990s. The increases of agricultural NPS pollution in China is evaluated for the period 2000-2008 by surveying the literature on water and soil pollution from fertilizers and pesticides, and assessing the surplus nitrogen balance within provinces. The main causes for NPS pollution were excessive inputs of nitrogen fertilizer and pesticides, which were partly the result of the inadequate agricultural extension services and the rapid expansion of intensive livestock production with little of waste management. The annual application of synthetic nitrogen fertilizers and pesticides in China increased by 50.7 and 119.7%, respectively, during 1991-2008. The mitigation measures to reduce NPS pollution include: correct distortion in fertilizer prices; improve incentives for the recycling of organic manure; provide farmers with better information on the sound use of agro-chemicals; and tighten the regulations and national standards on organic waste disposal and pesticides use.

  19. Wind farm induced changes in wind speed and surface fluxes over the North Sea

    NASA Astrophysics Data System (ADS)

    Chatterjee, Fabien; van Lipzig, Nicole; Meyers, Johan

    2016-04-01

    Offshore wind farm deployment in the North Sea is foreseen to expand dramatically in the coming years. The strong expansion of offshore wind parks is likely to affect the regional climatology on the North Sea. We assess this impact by conducting a regional climate model simulation over future wind farms built near the German coast. In order to achieve this, the wind farm parameterisation of Fitch et al. 2012, where wind farms are parameterised as elevated sources of turbulent kinetic energy and sinks of momentum ( Blahak et al 2010 and Fitch et al 2012) is implemented in COSMO-CLM at a 1.5 km resolution. As a first step, COSMO-CLM's ability to reproduce wind profiles over the North Sea is evaluated using wind speed data from the FINO1 meteorological mast, toghether with QuikScat scatterometer data, for a time period of 2000-2008. Subsequently, the impact of windfarms on the regional climate over a period of ten years (1999-2008) is assessed. A large scale wind farm can create wakes which depending on the wind direction could affect the power production of a neighbouring farm. Furthermore, wind farms decelerate the flow and create a vertical circulation in the inflow region. As a result, changes in vertical fluxes of moisture are observed. This leads to enhanced low level cloud cover which may trigger changes in precipitation.

  20. Review of the malaria epidemiology and trends in Zambia

    PubMed Central

    Masaninga, Freddie; Chanda, Emmanuel; Chanda-Kapata, Pascalina; Hamainza, Busiku; Masendu, Hieronymo T; Kamuliwo, Mulakwa; Kapelwa, Wambinji; Chimumbwa, John; Govere, John; Otten, Mac; Fall, Ibrahima Soce; Babaniyi, Olusegun

    2013-01-01

    A comprehensive desk review of malaria trends was conducted between 2000-2010 in Zambia to study malaria epidemiology and trends to guide strategies and approaches for effective malaria control. This review considered data from the National Health Information Management System, Malaria Surveys and Programme Review reports and analyzed malaria in-patient cases and deaths in relation to intervention coverage for all ages. Data showed three distinct epidemiological strata after a notable malaria reduction (66%) in in-patient cases and deaths, particularly between 2000-2008. These changes occurred following the (re-)introduction and expansion of indoor residual spraying up to 90% coverage, scale-up of coverage of long-lasting insecticide-treated nets in household from 50% to 70%, and artemisin-based combination therapy nationwide. However, malaria cases and deaths re-surged, increasing in 2009-2010 in the northern-eastern parts of Zambia. Delays in the disbursement of funds affected the implementation of interventions, which resulted in resurgence of cases and deaths. In spite of a decline in malaria disease burden over the past decade in Zambia, a reversal in impact is notable in the year 2009-2010, signifying that control gains are fragile and must be sustained toeliminate malaria. PMID:23593585

  1. A systematic review of parenting in relation to the development of comorbidities and functional impairments in children with attention-deficit/hyperactivity disorder (ADHD).

    PubMed

    Deault, Louise C

    2010-04-01

    This review synthesizes recent research evidence regarding the parenting characteristics associated with families with children with Attention-Deficit/Hyperactivity Disorder (ADHD). ADHD is a complex, heterogeneous disorder with a range of genetic and environmental factors that contribute to its behavioral expression and different developmental trajectories. The current review adopts a developmental psychopathology perspective to conceptualize the risk and protective factors that might shape the developmental pathways of the disorder across different domains. Following from Johnston and Mash's review (Johnston and Mash, Clin Child Fam Psychol Rev 4:183-207, 2001), the present review systematically examines empirical studies from 2000-2008 that investigate parenting variables in relation to the development of children with ADHD, with a particular focus on the development of externalizing and internalizing comorbidities, as well as functional impairments in academic and social contexts. The most recent research evidence uses correlational designs to show that ADHD is associated with problematic family functioning, including greater stress within the family, higher rates of parental psychopathology and conflicted parent-child relationships, which appears to be exacerbated in children with comorbid oppositional and conduct problems. However, there is an absence of literature that considers the role that parents play in contributing to children's development in areas such as academic achievement and peer competence, as well as the development of internalizing difficulties. Future research should examine family factors that are associated with resilience in children with ADHD, using longitudinal designs that reflect the dynamic changes associated with a developmental psychopathology framework.

  2. Remotely-Sensed Glacial Velocities: Mt. Shasta Advance vs. Sierra Nevada Retreat

    NASA Astrophysics Data System (ADS)

    Thompson, J. A.; Bookhagen, B.; Burbank, D. W.

    2008-12-01

    Monitoring changes in alpine glaciers is crucial to understanding the impacts of global climate change because alpine glacier systems respond quickly to changes in the earth´s climate. The glaciers of the Sierra Nevada and southern Cascades are of particular interest because they provide a major water reservoir to the state of California. Oddly, while most glaciers worldwide (including in the Sierra Nevada) are retreating, glaciers in northern California are advancing, and examining differences between these two locations will help resolve this paradox. Whereas previous studies have mapped the spatial extents of glaciers from aerial and satellite imagery, this study utilizes glacial velocities as a monitoring tool to examine the differences of the glaciers in the Sierra Nevada and on Mount Shasta. Using the program COSI-Corr in ENVI, horizontal surface ice flow velocities are calculated at the subpixel level from a time-series of co-registered, orthorectified, and correlated, late-summer satellite imagery. Through a combination of 15-meter Advanced Spaceborne Thermal Emission Radiometer (ASTER) and 5-meter SPOT imagery, orthorectified using a 15-meter resampled Shuttle Radar Topographic Mission (SRTM) digital elevation model (DEM), glacial velocities are derived on major glaciers on Mount Shasta and in the Palisades of the Sierra Nevada for 2000-2008. This study demonstrates the utility of combining various types of remote sensing imagery to create a complete time record, and from this record derive glacial velocities for use in monitoring climate change effectively.

  3. Scleractinian coral population size structures and growth rates indicate coral resilience on the fringing reefs of North Jamaica.

    PubMed

    Crabbe, M J C

    2009-01-01

    Coral reefs throughout the world are under severe challenges from many environmental factors. This paper quantifies the size structure of populations and the growth rates of corals from 2000 to 2008 to test whether the Discovery Bay coral colonies showed resilience in the face of multiple acute stressors of hurricanes and bleaching. There was a reduction in numbers of colonies in the smallest size class for all the species at all the sites in 2006, after the mass bleaching of 2005, with subsequent increases for all species at all sites in 2007 and 2008. Radial growth rates (mm yr(-1)) of non-branching corals and linear extension rates (mm yr(-1)) of branching corals calculated on an annual basis from 2000-2008 showed few significant differences either spatially or temporally. At Dairy Bull reef, live coral cover increased from 13+/-5% in 2006 to 20+/-9% in 2007 and 31+/-7% in 2008, while live Acropora species increased from 2+/-2% in 2006 to 10+/-4% in 2007 and 22+/-7% in 2008. These studies indicate good levels of coral resilience on the fringing reefs around Discovery Bay in Jamaica.

  4. The sea level fingerprint of recent ice mass fluxes

    NASA Astrophysics Data System (ADS)

    Bamber, J.; Riva, R.

    2010-12-01

    The sea level contribution from glacial sources has been accelerating during the first decade of the 21st Century (Meier et al., 2007; Velicogna, 2009). This contribution is not distributed uniformly across the world's oceans due to both oceanographic and gravitational effects. We compute the sea level signature for ice mass fluxes due to changes in the gravity field, Earth's rotation and related effects for the nine year period 2000-2008. Mass loss from Greenland results in a relative sea level (RSL) reduction for much of North Western Europe and Eastern Canada. RSL rise from this source is concentrated around South America. Losses in West Antarctica marginally compensate for this and produce maxima along the coastlines of North America, Australia and Oceania. The combined far-field pattern of wastage from all ice melt sources, is dominated by losses from the ice sheets and results in maxima at latitudes between 20° N and 40° S across the Pacific and Indian Oceans, affecting particularly vulnerable land masses in Oceania. The spatial pattern of RSL variations from ice mass losses used in this study is time-invariant and cumulative. Thus, sea level rise, based on the gravitational effects from the ice losses considered here, will be amplified for this sensitive region.

  5. A spatial and temporal analysis of child pedestrian crashes in Santiago, Chile.

    PubMed

    Blazquez, Carola A; Celis, Marcela S

    2013-01-01

    This paper presents a spatial and temporal analysis of child pedestrian crash data in Santiago, Chile during the period 2000-2008. First, this study identified seven critical areas with high child pedestrian crash risk employing kernel density estimation, and subsequently, statistically significant clusters of the main attributes associated to these crashes in each critical area were determined in a geographic information systems environment. Moran's I index test identified a positive spatial autocorrelation on crash contributing factors, time of day, straight road sections and intersections, and roads without traffic signs within the critical areas during the studied period, whereas a random spatial pattern was identified for crashes related to the age attribute. No statistical significance in the spatial relationship was obtained in child pedestrian crashes with respect to gender, weekday, and month of the year. The results from this research aid in determining the areas in which enhanced school-age child pedestrian safety is required by developing and implementing effective enforcement, educational, and engineering preventive measures.

  6. Effects of tropical cyclones on large-scale circulation and ocean heat transport in the South China Sea

    NASA Astrophysics Data System (ADS)

    Wang, Xidong; Wang, Chunzai; Han, Guijun; Li, Wei; Wu, Xinrong

    2014-12-01

    In this study, we investigate the influence of tropical cyclones (TCs) on large-scale circulation and ocean heat transport in the South China Sea (SCS) by using an ocean general circulation model at a 1/8° resolution during 2000-2008. The model uses a data assimilation system to assimilate observations in order to improve the representation of SCS circulation. The results reveal an unexpected deep SCS circulation anomaly induced by TCs, which suggests that effects of TC can penetrate deeper into the ocean. This deep effect may result from the near inertial oscillations excited by TCs. The inertial oscillations can propagate downward to the oceanic interior. The analyses confirm that TCs have two effects on ocean heat transport of the SCS. Firstly, the wind stress curl induced by TCs affects the structure of SCS circulation, and then changes heat transport. Secondly, TCs pump surface heat downward to the thermocline, increasing the heat injection from the atmosphere to the ocean. Two effects together amplify the outflow of the surface heat southward away the SCS through the Mindoro and Karimata Straits. The TC-induced heat transports through the Mindoro, Balabac and Karimata Straits account for 20 % of the total heat transport through three straits. An implication of this study is that ocean models need to simulate the TC effect on heat transport in order to correctly evaluate the role of the SCS through flow in regulating upper ocean circulation and climate in the Indonesian maritime continent and its adjacent regions.

  7. [Analysis on sustainable development of marine economy in Jiangsu Province based on marine ecological footprint correction model].

    PubMed

    Yang, Shan; Wang, Yu-ting

    2011-03-01

    Based on the theories and methods of ecological footprint, the concept of marine ecological footprint was proposed. According to the characteristics of marine environment in Jiangsu Province, five sub-models of marine ecological footprints, including fishery, transporation, marine engineering construction, marine energy, and tidal flat, were constructed. The equilibrium factors of the five marine types were determined by using improved entropy method, and the marine footprints and capacities in Jiangsu Province from 2000 to 2008 were calculated and analyzed. In 2000-2008, the marine ecology footprint per capita in Jiangsu Province increased nearly seven times, from 36.90 hm2 to 252.94 hm2, and the ecological capacity per capita grew steadily, from 105.01 hm2 to 185.49 hm2. In 2000, the marine environment in the Province was in a state of ecological surplus, and the marine economy was in a weak sustainable development state. Since 2004, the marine ecological environment deteriorated sharply, with ecological deficit up to 109660.5 hm2, and the sustainability of marine economy declined. The high ecological footprint of fishery was the main reason for the ecological deficit. Tidal flat was the important reserve resource for the sustainable development of marine economy in Jiangsu Province.

  8. Prevalence, incidence, and comorbidity of clinically diagnosed obsessive-compulsive disorder in Taiwan: a national population-based study.

    PubMed

    Huang, Li-Chung; Tsai, Kuen-Jer; Wang, Hao-Kuang; Sung, Pi-Shan; Wu, Ming-Hsiu; Hung, Kuo-Wei; Lin, Sheng-Hsiang

    2014-12-15

    Obsessive-compulsive disorder (OCD) is a chronic debilitating anxiety disorder significant in intrusive thoughts and compensation repetitive behaviors. Few studies have reported on this condition Asia. This study estimated the prevalence, incidence and psychiatric comorbidities of OCD in Taiwan. We identified study subjects for 2000-2008 with a principal diagnosis of OCD according to the International Classification of Disease, 9th Revision, Clinical Modification (ICD-9-CM) diagnostic criteria by using National Health Research Institute database. These patients received either outpatient or inpatient care for their condition. Rates were directly age- and sex-adjusted to the 2004 Taiwan population distribution. The estimated mean annual incidence was 27.57 per 10(5) inhabitants and the one year prevalence was 65.05 per 10(5) inhabitants. Incidence and prevalence increased with age, peaking at age 18-24 years in males and at 35-44 years in females. About 53% of adults (≥18 years) and 48% of child and adolescent patients (6-17 years) had one or more comorbid psychiatric conditions. The most common comorbid diagnosis was depressive disorders for both adult and child-adolescent patients. We found a lower prevalence and incidence of clinically diagnosed OCD than that of community studies. Many Asian patients with OCD also had various psychiatric comorbidities, a clinically relevant finding.

  9. Impact of universal vaccination on the epidemiology of varicella in Veneto, Italy.

    PubMed

    Pozza, Francesca; Piovesan, Cinzia; Russo, Francesca; Bella, Antonino; Pezzotti, Patrizio; Emberti Gialloreti, Leonardo

    2011-11-28

    In 2005, universal varicella vaccination was introduced in the Veneto region, Italy. We examined trends in varicella incidence and hospitalization rates before and after vaccine introduction, and applied statistical models to assess vaccine effectiveness. Varicella incidence rates for 2000-2008 were calculated from the mandatory regional surveillance data and from a special surveillance system based on reports from a sample of family pediatricians that during the study period followed more than 40,000 children. To evaluate hospital admission rates, we analyzed the regional hospital discharge registry. The vaccine coverage rate was 6.8% in the 2004 birth-cohort and 78.6% in the 2008 cohort. Varicella incidence in 0-14 year-olds was 6136.8/100,000 person-years in 2000 and 4004.8 in 2008; hospitalization rates were 18.7 and 8.4. Incidence rates significantly decreased 2.5 years after beginning the universal vaccination, while hospitalization rates showed a significant decrease one year earlier. There was a remarkable decline of both varicella incidence and hospitalizations especially in 1-4 year-old children. This study confirms the positive impact of universal vaccination. Copyright © 2011 Elsevier Ltd. All rights reserved.

  10. Salmonellosis and charter tourism: epidemiology and trends of imported human cases to Norway from the Canary Islands and Thailand, 1994-2008.

    PubMed

    Emberland, K E; Nygård, K; Aavitsland, P

    2012-09-01

    More than 70% of reported human Salmonella infections in Norway are infected abroad. The Canary Islands and Thailand are two of the most popular charter tourist destinations for Norwegians. Using surveillance data for the years 1994-2008, and denominator data on travel to the Canary Islands 2000-2008 and to Thailand 1997-2008, we present the epidemiology and trends of Salmonella infections in Norwegian tourists to these destinations. We found a declining trend in risk of salmonellosis in tourists returning from the Canary Islands, and a change in serovar distribution in travellers to Thailand with more S. Enteritidis infections, similar to that observed in Western European countries. The use of denominator data is important when studying risk of travel-related disease, as surveillance data tend to reflect travel activity more than the risk. Infections among tourists do not always affect the local residents and therefore may not be detected by local public health authorities. Sharing knowledge on the epidemiology of infections in tourists could be useful for observation of changes in trends in the countries visited, and in future outbreak investigations.

  11. A policy-driven large scale ecological restoration: quantifying ecosystem services changes in the Loess Plateau of China.

    PubMed

    Lü, Yihe; Fu, Bojie; Feng, Xiaoming; Zeng, Yuan; Liu, Yu; Chang, Ruiying; Sun, Ge; Wu, Bingfang

    2012-01-01

    As one of the key tools for regulating human-ecosystem relations, environmental conservation policies can promote ecological rehabilitation across a variety of spatiotemporal scales. However, quantifying the ecological effects of such policies at the regional level is difficult. A case study was conducted at the regional level in the ecologically vulnerable region of the Loess Plateau, China, through the use of several methods including the Universal Soil Loss Equation (USLE), hydrological modeling and multivariate analysis. An assessment of the changes over the period of 2000-2008 in four key ecosystem services was undertaken to determine the effects of the Chinese government's ecological rehabilitation initiatives implemented in 1999. These ecosystem services included water regulation, soil conservation, carbon sequestration and grain production. Significant conversions of farmland to woodland and grassland were found to have resulted in enhanced soil conservation and carbon sequestration, but decreased regional water yield under a warming and drying climate trend. The total grain production increased in spite of a significant decline in farmland acreage. These trends have been attributed to the strong socioeconomic incentives embedded in the ecological rehabilitation policy. Although some positive policy results have been achieved over the last decade, large uncertainty remains regarding long-term policy effects on the sustainability of ecological rehabilitation performance and ecosystem service enhancement. To reduce such uncertainty, this study calls for an adaptive management approach to regional ecological rehabilitation policy to be adopted, with a focus on the dynamic interactions between people and their environments in a changing world.

  12. Forecasting the future risk of Barmah Forest virus disease under climate change scenarios in Queensland, Australia.

    PubMed

    Naish, Suchithra; Mengersen, Kerrie; Hu, Wenbiao; Tong, Shilu

    2013-01-01

    Mosquito-borne diseases are climate sensitive and there has been increasing concern over the impact of climate change on future disease risk. This paper projected the potential future risk of Barmah Forest virus (BFV) disease under climate change scenarios in Queensland, Australia. We obtained data on notified BFV cases, climate (maximum and minimum temperature and rainfall), socio-economic and tidal conditions for current period 2000-2008 for coastal regions in Queensland. Grid-data on future climate projections for 2025, 2050 and 2100 were also obtained. Logistic regression models were built to forecast the otential risk of BFV disease distribution under existing climatic, socio-economic and tidal conditions. The model was applied to estimate the potential geographic distribution of BFV outbreaks under climate change scenarios. The predictive model had good model accuracy, sensitivity and specificity. Maps on potential risk of future BFV disease indicated that disease would vary significantly across coastal regions in Queensland by 2100 due to marked differences in future rainfall and temperature projections. We conclude that the results of this study demonstrate that the future risk of BFV disease would vary across coastal regions in Queensland. These results may be helpful for public health decision making towards developing effective risk management strategies for BFV disease control and prevention programs in Queensland.

  13. 50th anniversary of the Declaration of Helsinki: the double standard was introduced.

    PubMed

    Hellmann, Fernando; Verdi, Marta; Schlemper, Bruno Rodolfo; Caponi, Sandra

    2014-10-01

    The Declaration of Helsinki (DoH), adopted by the World Medical Association (WMA), is one of the most influential international documents in research ethics, is turning 50 in 2014. Its regular updates, seven versions (1975, 1983, 1989, 1996, 2000, 2008, 2013) and two notes of clarification (2002, 2004), characterize it as a 'live' document. The seventh version of the DoH was amended by the 64th WMA General Assembly, Fortaleza, Brazil, October 2013. The new version was reorganized and restructured, with paragraphs subdivided and regrouped. However, the DoH remains controversial and some ethical issues are still uncovered. The major problem was the insertion of the phrase 'less effective than the best proven' on placebo paragraph in order to allow double standard in medical research in low-resource countries. The DoH is a 'live' document, which will continually have to deal with new topics and challenges. Health equity needs to be a priority, and with that, a single ethical standard for medical research. Copyright © 2014 IMSS. Published by Elsevier Inc. All rights reserved.

  14. Cancer research performance in the European Union: a study of published output from 2000 to 2008.

    PubMed

    Micheli, Andrea; Di Salvo, Francesca; Lombardo, Claudio; Ugolini, Donatella; Baili, Paolo; A Pierotti, Marco

    2011-01-01

    Although several studies have assessed cancer research performance in individual European countries, comparisons of European Union (EU27) performance with countries of similar population size are not available. We compared cancer research performance in 2000-2008 between EU27 and 11 countries with over 100 million inhabitants. Performance should not have been affected by the 2007-2009 recession. We examined 143 journals considered oncology journals by Journal Citation Reports, accessing them via Scopus. Publications were attributed to countries using a published counting procedure. For number of publications, the USA held a clear lead in 2006-2008 (yearly averages: 10,293 USA vs 9,962 EU27), whereas the EU27 held the lead previously. EU27 was also second to the USA for total impact factor. China markedly improved its cancer publications record over the period. Compared to the USA, EU27 and Japan, the other countries (all developing) had a poor publications record. Comparative cancer research spending data are not available. However from 2002 to 2007, gross domestic expenditure on research and development (UNESCO data) increased by 34% in North America, 161% in China and only 28% in EU27. Thus the European Union is lagging behind North America and may well be eclipsed by China in research and development spending in the near future. We suggest that these new findings should be considered by policymakers in Europe and other countries when developing policies for cancer control.

  15. Education associations with smoking and leisure-time physical inactivity among Hispanic and Asian young adults.

    PubMed

    Stoddard, Pamela; Adler, Nancy E

    2011-03-01

    We assessed whether associations between education and 2 health behaviors--smoking and leisure-time physical inactivity (LTPI)--depended on nativity and age at immigration among Hispanic and Asian young adults. Data came from the 2000-2008 National Health Interview Survey. The sample included 13 345 Hispanics and 2528 Asians aged 18 to 30 years. Variables for smoking and LTPI were based on self-reported data. We used logistic regression to examine education differentials in these behaviors by nativity and age at immigration. The association of education with both smoking and LTPI was weaker for foreign-born Hispanics than for US-born Hispanics but did not vary by nativity for Asians. Education associations for smoking and LTPI among foreign-born Hispanics who had immigrated at an early age more closely resembled those of US-born Hispanics than did education associations among foreign-born Hispanics who had immigrated at an older age. A similar pattern for smoking was evident among Asians. Health-promotion efforts aimed at reducing disparities in key health behaviors among Hispanic and Asian young adults should take into account country of residence in childhood and adolescence as well as nativity.

  16. Pregnancy-related uterine arteriovenous malformations: experience from a single medical center.

    PubMed

    Vaknin, Z; Sadeh-Mefpechkin, D; Halperin, R; Altshuler, A; Amir, P; Maymon, R

    2011-12-01

    The purpose of this article was to investigate clinical ultrasonographic findings and the outcomes of post-pregnancy patients with acquired uterine vascular abnormalities including arteriovenous malformations (AVMs). We performed a computerized database search for all patients with ultrasonographic findings of a vascular abnormality including AVM in our referral center between 2000-2008. An ultrasound finding of vascular abnormality was defined as an area of strong hypervascularity within the myometrium and the presence of marked turbulence. The inclusion criteria for angiography were abnormal vaginal bleeding in a hemodynamically stable patient, bhCG serum levels ≤ 30 mIU/ml, and ultrasound demonstration of large (≥ 15 mm on the larger side of the vessel) or multiple vascular lesions. 16 women were identified, of whom 10 (63 %) underwent uterine artery embolization. Angiography confirmed the pre-interventional ultrasound diagnosis of AVM in all cases. AVM feeding arteries were on the left side of the uterus in 80 % of the cases. Residual tissue was ultrasonographically detected in five patients: 2 underwent hysteroscopy and guided curettage following embolization and three received methotrexate. All tissue samples were benign. One small vascular abnormality resolved spontaneously. An acquired uterine vascular abnormality including AVM should be considered in the work-up of post-pregnancy vaginal bleeding. © Georg Thieme Verlag KG Stuttgart · New York.

  17. [Dynamics of forest fire weather indices in Tahe County of Great Xing' an Mountains region, Heilongjiang Province].

    PubMed

    Di, Xue-Ying; Li, Yong-Fu; Sun, Jian; Yang, Guang

    2011-05-01

    Based on the 1974-2008 forest fire and meteorological data in Tahe County of Great Xing' an Mountains region, and with the help of Canadian Forest Fire Weather Index System (CFFWIS), this paper qualitatively and quantitatively analyzed the dynamics of forest fire weather indices in the region. In 1974-2008, the mean annual fire occurrence in the region showed an increasing trend, and the increment in 2000-2008 was 72.2%, compared with that in 1974-1999. The fuel moisture codes, fire behavior indices, and fire severity indices in 1974-2008 had an overall increasing trend, which was more evident with time extended. In the future, the probability of forest fire occurrence in the region would be increasing, fuels would be getting drier, fire intensity would be increased, fire weather would be more serious, and fire control would be more difficult. Therefore, more efforts should be made to improve the capability of forest fire control, especially in summer. As a fundamental technique, prescribed burning should be applied to reduce the fuel load. From this doing, the probability of fire occurrence and the fire potential intensity could be reduced.

  18. Occupational exposure to magnetic fields and electric shocks and risk of ALS: the Swiss National Cohort.

    PubMed

    Huss, Anke; Spoerri, Adrian; Egger, Matthias; Kromhout, Hans; Vermeulen, Roel

    2015-03-01

    Amyotrophic lateral sclerosis (ALS) has been associated with exposures in so-called 'electrical occupations'. It is unclear if this possible link may be explained by exposure to extremely low-frequency magnetic fields (ELF-MF) or by electrical shocks. We evaluated ALS mortality in 2000-2008 and exposure to ELF-MF and electrical shocks in the Swiss National Cohort, using job exposure matrices for occupations at censuses 1990 and 2000. We compared 2.2 million workers with high or medium vs. low exposure to ELF-MF and electrical shocks using Cox proportional hazard models. Results showed that mortality from ALS was higher in people who had medium or high ELF-MF exposure in both censuses (HR 1.55 (95% CI 1.11-2.15)), but closer to unity for electrical shocks (HR 1.17 (95% CI 0.83-1.65)). When both exposures were included in the same model, the HR for ELF-MF changed little (HR 1.56), but the HR for electric shocks was attenuated to 0.97. In conclusion, there was an association between exposure to ELF-MF and mortality from ALS among workers with a higher likelihood of long-term exposure.

  19. ON THE SPIN-DOWN AND MAGNETIC FIELD OF THE X-RAY PULSAR 1E 1207.4-5209

    SciTech Connect

    Halpern, J. P.; Gotthelf, E. V. E-mail: eric@astro.columbia.edu

    2011-06-01

    We analyze all of the archival X-ray timing data from the years 2000-2008 on the weakly magnetized central compact object (CCO) pulsar 1E 1207.4-5209 in an attempt to measure its dipole magnetic field strength via spin-down. because most of these observations were not planned for the purpose of phase-coherent timing, the resulting ephemeris is not unique, but is restricted to two comparably good timing solutions that correspond to B{sub s} = 9.9 x 10{sup 10} G or 2.4 x 10{sup 11} G, respectively, assuming dipole spin-down. One of these should be the correct value and the other one an alias. There are no spinning-up solutions. The smaller value of B{sub s} is close to the surface field of 8 x 10{sup 10} G that is measured independently from the unique absorption lines in the X-ray spectrum of 1E 1207.4-5209, assuming that the lowest-energy line at 0.7 keV is the electron-cyclotron fundamental. We suggest that 1E 1207.4-5209 has the strongest magnetic field among CCOs, which would account for the unique presence of its cyclotron absorption spectrum, while other CCOs likely have even weaker fields for which the cyclotron fundamental falls below the observable soft X-ray band.

  20. Quality of Spine Surgery Research from the Arab Countries: A Systematic Review and Bibliometric Analysis.

    PubMed

    Baeesa, Saleh S; Maghrabi, Yazid; Msaddi, Abdul Karim; Assaker, Richard

    2017-01-01

    Purpose. The purpose of our study is to evaluate the level of evidence (LOE) of spine surgery publications in the Arab countries and compare it with standard international literature in spine surgery and to determine the stand of the Arab nations academic production with that of the global one. Methods. An online search using "PubMed" and "Google Scholar" was carried out, using search terms related to spine surgery such as "Spine surgery," "Scoliosis," "Herniated disc." Each article was reviewed and graded by two reviewers using Oxford Centre for Evidence-Based Medicine (OCEBM) Levels of Evidence scale. Results. We have identified 434 articles that met the inclusion criteria; 56% were level IV studies. The most common study design was case reports (42%). The number of Arab countries with publications in spine surgery was 18 countries. The country with the highest rate of publications was Egypt (26%). The quantity of the published studies increased from 151 in (2000-2008) to 283 in (2009-2015). There is statistical significance between high and low LOE articles (p = 0.0007). Conclusion. We have observed that LOE has not changed significantly over the period of 15 years and that much of the publications are of a low LOE (levels III and IV). We, herein, emphasize the need for spine surgeons in the Arab countries to conduct studies of higher LOE.

  1. Land use effects on green water fluxes from agricultural production in Mato Grosso, Brazil

    NASA Astrophysics Data System (ADS)

    Lathuilliere, M. J.; Johnson, M. S.; Donner, S. D.

    2010-12-01

    The blue water/green water paradigm is increasingly used to differentiate between subsequent routing of precipitation once it reaches the soil. “Blue” water is that which infiltrates deep in the soil to become streams and aquifers, while “green” water is that which remains in the soil and is either evaporated (non-productive green water) or transpired by plants (productive green water). This differentiation in the fate of precipitation has provided a new way of thinking about water resources, especially in agriculture for which better use of productive green water may help to relieve stresses from irrigation (blue water). The state of Mato Grosso, Brazil, presents a unique case for the study of green water fluxes due to an expanding agricultural land base planted primarily to soybean, maize, sugar cane, and cotton. These products are highly dependent on green water resources in Mato Grosso where crops are almost entirely rain-fed. We estimate the change in green water fluxes from agricultural expansion for the 2000-2008 period in the state of Mato Grosso based on agricultural production data from the Instituto Brasileiro de Geografia e Estatísticas and a modified Penman-Monteith equation. Initial results for seven municipalities suggest an increase in agricultural green water fluxes, ranging from 1-10% per year, due primarily to increases in cropped areas. Further research is underway to elucidate the role of green water flux variations from land use practices on the regional water cycle.

  2. Life is Getting Better: Societal Evolution and Fit with Human Nature.

    PubMed

    Veenhoven, Ruut

    2010-05-01

    Human society has changed much over the last centuries and this process of 'modernization' has profoundly affected the lives of individuals; currently we live quite different lives from those forefathers lived only five generations ago. There is difference of opinion as to whether we live better now than before and consequently there is also disagreement as to whether we should continue modernizing or rather try to slow the process down. Quality-of-life in a society can be measured by how long and happy its inhabitants live. Using these indicators I assess whether societal modernization has made life better or worse. Firstly I examine findings of present day survey research. I start with a cross-sectional analysis of 143 nations in the years 2000-2008 and find that people live longer and happier in today's most modern societies. Secondly I examine trends in modern nations over the last decade and find that happiness and longevity have increased in most cases. Thirdly I consider the long-term and review findings from historical anthropology, which show that we lived better in the early hunter-gatherer society than in the later agrarian society. Together these data suggest that societal evolution has worked out differently for the quality of human life, first negatively, in the change from a hunter-gatherer existence to agriculture, and next positively, in the more recent transformation from an agrarian to an industrial society. We live now longer and happier than ever before.

  3. Predictability of mesoscale circulation throughout the water column in the Gulf of Mexico

    NASA Astrophysics Data System (ADS)

    Cardona, Yuley; Bracco, Annalisa

    2016-07-01

    The predictability of the mesoscale circulation in the Gulf of Mexico is evaluated using an ensemble of four integrations for the period 2000-2008 using the Regional Ocean Modeling System (ROMS). In all four runs ROMS is forced by identical, monthly varying, heat and momentum fluxes. We explore the role of initial conditions, boundary conditions, atmospheric forcing, and resolution in the Mississippi plume area, on the potential predictability of the Gulf circulation at scales of 20 km or greater. The potential for predictability varies regionally and seasonally. The modeled circulation is mainly atmospherically forced in the coastal areas and dominated by chaotic mesoscale activity in the central portion of the basin. The mesoscale circulation in the top 1000 m of the water column does not correlate with the one below it except for a limited number of small areas. The potential for predicting the circulation at depths deeper than 1000 m is limited by the intrinsic variability of the eddy field and by the unavailability of a continuous monitoring system that extends below the surface.

  4. Review of the malaria epidemiology and trends in Zambia.

    PubMed

    Masaninga, Freddie; Chanda, Emmanuel; Chanda-Kapata, Pascalina; Hamainza, Busiku; Masendu, Hieronymo T; Kamuliwo, Mulakwa; Kapelwa, Wambinji; Chimumbwa, John; Govere, John; Otten, Mac; Fall, Ibrahima Soce; Babaniyi, Olusegun

    2013-02-01

    A comprehensive desk review of malaria trends was conducted between 2000-2010 in Zambia to study malaria epidemiology and trends to guide strategies and approaches for effective malaria control. This review considered data from the National Health Information Management System, Malaria Surveys and Programme Review reports and analyzed malaria in-patient cases and deaths in relation to intervention coverage for all ages. Data showed three distinct epidemiological strata after a notable malaria reduction (66%) in in-patient cases and deaths, particularly between 2000-2008. These changes occurred following the (re-)introduction and expansion of indoor residual spraying up to 90% coverage, scale-up of coverage of long-lasting insecticide-treated nets in household from 50% to 70%, and artemisin-based combination therapy nationwide. However, malaria cases and deaths re-surged, increasing in 2009-2010 in the northern-eastern parts of Zambia. Delays in the disbursement of funds affected the implementation of interventions, which resulted in resurgence of cases and deaths. In spite of a decline in malaria disease burden over the past decade in Zambia, a reversal in impact is notable in the year 2009-2010, signifying that control gains are fragile and must be sustained to eliminate malaria.

  5. Impact of pharmacometric analyses on new drug approval and labelling decisions: a review of 198 submissions between 2000 and 2008.

    PubMed

    Lee, Joo Yeon; Garnett, Christine E; Gobburu, Jogarao V S; Bhattaram, Venkatesh A; Brar, Satjit; Earp, Justin C; Jadhav, Pravin R; Krudys, Kevin; Lesko, Lawrence J; Li, Fang; Liu, Jiang; Madabushi, Rajnikanth; Marathe, Anshu; Mehrotra, Nitin; Tornoe, Christoffer; Wang, Yaning; Zhu, Hao

    2011-10-01

    Pharmacometric analyses have become an increasingly important component of New Drug Application (NDA) and Biological License Application (BLA) submissions to the US FDA to support drug approval, labelling and trial design decisions. Pharmacometrics is defined as a science that quantifies drug, disease and trial information to aid drug development, therapeutic decisions and/or regulatory decisions. In this report, we present the results of a survey evaluating the impact of pharmacometric analyses on regulatory decisions for 198 submissions during the period from 2000 to 2008. Pharmacometric review of NDAs included independent, quantitative analyses by FDA pharmacometricians, even when such analysis was not conducted by the sponsor, as well as evaluation of the sponsor's report. During 2000-2008, the number of reviews with pharmacometric analyses increased dramatically and the number of reviews with an impact on approval and labelling also increased in a similar fashion. We also present the impact of pharmacometric analyses on selection of paediatric dosing regimens, approval of regimens that had not been directly studied in clinical trials and provision of evidence of effectiveness to support a single pivotal trial. Case studies are presented to better illustrate the role of pharmacometric analyses in regulatory decision making.

  6. Recent Rates of Forest Harvest and Conversion in North America

    NASA Technical Reports Server (NTRS)

    Masek, Jeffrey G.; Cohen, Warren B.; Leckie, Donald; Wulder, Michael A.; Vargas, Rodrigo; de Jong, Ben; Healey, Sean; Law, Beverly; Birdsey, Richard; Houghton, R. A.; hide

    2011-01-01

    Incorporating ecological disturbance into biogeochemical models is critical for estimating current and future carbon stocks and fluxes. In particular, anthropogenic disturbances, such as forest conversion and wood harvest, strongly affect forest carbon dynamics within North America. This paper summarizes recent (2000.2008) rates of extraction, including both conversion and harvest, derived from national forest inventories for North America (the United States, Canada, and Mexico). During the 2000s, 6.1 million ha/yr were affected by harvest, another 1.0 million ha/yr were converted to other land uses through gross deforestation, and 0.4 million ha/yr were degraded. Thus about 1.0% of North America fs forests experienced some form of anthropogenic disturbance each year. However, due to harvest recovery, afforestation, and reforestation, the total forest area on the continent has been roughly stable during the decade. On average, about 110 m3 of roundwood volume was extracted per hectare harvested across the continent. Patterns of extraction vary among the three countries, with U.S. and Canadian activity dominated by partial and clear ]cut harvest, respectively, and activity in Mexico dominated by conversion (deforestation) for agriculture. Temporal trends in harvest and clearing may be affected by economic variables, technology, and forest policy decisions. While overall rates of extraction appear fairly stable in all three countries since the 1980s, harvest within the United States has shifted toward the southern United States and away from the Pacific Northwest.

  7. Water-level altitudes 2008 and water-level changes in the Chicot, Evangeline, and Jasper Aquifers and compaction 1973-2007 in the Chicot and Evangeline Aquifers, Houston-Galveston Region, Texas

    USGS Publications Warehouse

    Kasmarek, Mark C.; Houston, Natalie A.

    2008-01-01

    This report, done in cooperation with the Harris-Galveston Subsidence District, the City of Houston, the Fort Bend Subsidence District, and the Lone Star Groundwater Conservation District, is one in an annual series of reports that depicts water-level altitudes and water-level changes in the Chicot, Evangeline, and Jasper aquifers, and compaction in the Chicot and Evangeline aquifers in the Houston-Galveston region, Texas. The report contains 17 sheets and 16 tables: 3 sheets are maps showing current-year (2008) water-level altitudes for each aquifer, respectively; 3 sheets are maps showing 1-year (2007-08) water-level changes for each aquifer, respectively; 3 sheets are maps showing 5-year (2003-08) water-level changes for each aquifer, respectively; 4 sheets are maps showing long-term (1990-2008 and 1977-2008) water-level changes for the Chicot and Evangeline aquifers, respectively; 1 sheet is a map showing long-term (2000-2008) water-level change for the Jasper aquifer; 1 sheet is a revision of a previously published water-level-altitude map for the Jasper aquifer for 2003; 1 sheet is a map showing site locations of borehole extensometers; and 1 sheet comprises graphs showing measured compaction of subsurface material at the sites from 1973 or later through 2007, respectively. Tables listing the data used to construct the aquifer-data maps and the compaction graphs are included.

  8. Socio-demographic vulnerability to heatwave impacts in Brisbane, Australia: a time series analysis.

    PubMed

    Toloo, Ghasem Sam; Guo, Yuming; Turner, Lyle; Qi, Xin; Aitken, Peter; Tong, Shilu

    2014-10-01

    Examining the association between socioeconomic disadvantage and heat-related emergency department (ED) visits during heatwave periods in Brisbane, 2000-2008. Data from 10 public EDs were analysed using a generalised additive model for disease categories, age groups and gender. Cumulative relative risks (RR) for non-external causes other than cardiovascular and respiratory diseases were 1.11 and 1.05 in most and least disadvantaged areas, respectively. The pattern persisted on lags 0-2. Elevated risks were observed for all age groups above 15 years in all areas. However, with RRs of 1.19-1.28, the 65-74 years age group in more disadvantaged areas stood out, compared with RR=1.08 in less disadvantaged areas. This pattern was observed on lag 0 but did not persist. The RRs for male presentations were 1.10 and 1.04 in most and less disadvantaged areas; for females, RR was 1.04 in less disadvantaged areas. This pattern persisted across lags 0-2. Heat-related ED visits increased during heatwaves. However, due to overlapping confidence intervals, variations across socioeconomic areas should be interpreted cautiously. ED data may be utilised for monitoring heat-related health impacts, particularly on the first day of heatwaves, to facilitate prompt interventions and targeted resource allocation. © 2014 Public Health Association of Australia.

  9. Meta-analysis of incidence and risk of hypokalemia with cetuximab-based therapy for advanced cancer.

    PubMed

    Cao, Yunfei; Liu, Lidan; Liao, Cun; Tan, Aihua; Gao, Feng

    2010-05-01

    To gain a better understanding of the incidence and risk of hypokalemia in patients who received cetuximab-based therapy. Databases, including Pubmed, EMBASE, The Cochrane Library, annual meeting of American Society of Clinical Oncology (2000-2008), and Web of science were searched to identify relevant studies. Eligible studies were prospective phase II-III clinical trials of patients with cancer assigned cetuximab at the dose of 400 mg/m(2) IV on day 1 and 250 mg/m(2) weekly thereafter. The primary endpoint was incidence of hypokalemia. Eleven clinical reports were identified which included a total of 2,254 patients who were available for analysis, with 1,324 patients assigned cetuximab-based treatment. The results showed high incidence of grade 3 and 4 hypokalemia [6.2% (95% CI 4.9-7.7)] and high incidence of all-grade hypokalemia [8.0% (95% CI 4.5-13.9)] associated with cetuximab-based therapy for advanced cancer. Compared with non-cetuximab therapy, cetuximab-based therapy has higher risk of grade 3 and 4 hypokalemia [1.81 (95% CI 1.12-2.93)]. Cetuximab-based therapy is associated with a significant risk of hypokalemia. Early monitoring and effective management of hypokalemia is important for patients that received cetuximab-based therapy.

  10. Distributional Impacts of Large Dams in China

    NASA Astrophysics Data System (ADS)

    Bao, X.

    2010-12-01

    Dams on a river are believed to have heterogeneous impacts to the upstream, local and downstream areas. Generally, irrigation dams will bring benefits to the downstream by facilitating more irrigation, while it will bring negative impacts to upstream due to inundation or no impact to local area as a combination result of population dislocation and economic benefits. This paper checked the impacts of large dams (above 100 meters) on the upstream, downstream and local area, using 2000-2008 county level data in China. Robust heterogeneous impacts of different categories of dams (mainly dams serving for irrigation, hydropower, or other purposes) were found on different areas, using IV regression approaches. Dams higher than 100 meters are significantly and heterogeneously impacting agricultural production, urban employment and rural per capita income. Its beneficial impact on agriculture production is significant for downstream especially in continuous drought years. But its impacts on social welfare indicators, such as primary school enrollment and hospital beds, are not heterogeneously different across regions.

  11. Influence of atmospheric states in semi-arid areas on hospital admission in cardio-surgical department

    NASA Astrophysics Data System (ADS)

    Yackerson, Naomy S.; Zilberman, Arkadi; Aizenberg, Alexander

    2016-10-01

    The influence of the changes in atmospheric state, typical for areas close to big deserts, on acute myocardial infarction (AMI) was analyzed. Under test was the group of 3256 patients (77 % males, 23 % females), hospitalized in the Cardio-Surgical Department of Soroka Medical Center at Ben-Gurion University (BGU, Israel) during 2000-2008. To explore the relationship between atmospheric parameters and AMI, multivariate regression analysis has been performed. AMI was most frequent in winter to spring and least in summer. The highest number of cases was recorded in December and the lowest in September. Hospital admissions showed a higher prevalence in men than in women; the ratio is 3.3/1.0. About 60 % of males were aged between 45 and 65 years old with maximum ˜55 (21 %), whereas 60 % of women hospital admissions were aged between 65 and 80 years old with maximum ˜72 (24 %). The result suggested that the monthly mean relative humidity at daytime and its overall daily differences, wind speed, and respirable fraction of particulate concentration are associated with the admission for AMI. The results of the study confirm the importance of atmospheric state variability for cardiovascular diseases.

  12. Changes in Rongbuk lake and Imja lake in the Everest region of Himalaya

    NASA Astrophysics Data System (ADS)

    Chen, W.; Doko, T.; Liu, C.; Ichinose, T.; Fukui, H.; Feng, Q.; Gou, P.

    2014-12-01

    The Himalaya holds the world record in terms of range and elevation. It is one of the most extensively glacierized regions in the world except the Polar Regions. The Himalaya is a region sensitive to climate change. Changes in the glacial regime are indicators of global climate changes. Since the second half of the last century, most Himalayan glaciers have melted due to climate change. These changes directly affected the changes of glacial lakes in the Himalayan region due to the glacier retreat. New glacial lakes are formed, and a number of them have expanded in the Everest region of the Himalayas. This paper focuses on the two glacial lakes which are Imja Lake, located at the southern slope, and Rongbuk Lake, located at the northern slope in the Mt. Everest region, Himalaya to present the spatio-temporal changes from 1976 to 2008. Topographical conditions between two lakes were different (Kruskal-Wallis test, p < 0.05). Rongbuk Lake was located at 623 m higher than Imja Lake, and radiation of Rongbuk Lake was higher than the Imja Lake. Although size of Imja Lake was larger than the Rongbuk Lake in 2008, the growth speed of Rongbuk Lake was accelerating since 2000 and exceeds Imja Lake in 2000-2008. This trend of expansion of Rongbuk Lake is anticipated to be continued in the 21st century. Rongbuk Lake would be the biggest potential risk of glacial lake outburst flood (GLOF) at the Everest region of Himalaya in the future.

  13. The impact of transfers on water quality and the disturbance regime in a reservoir.

    PubMed

    Fornarelli, Roberta; Antenucci, Jason P

    2011-11-15

    The effect of water transfers between two reservoirs on the water quality of the receiving reservoir was investigated over a 9-year period (2000-2008). Different management strategies were implemented in term of the magnitude and timing of water transfers, i.e. the amount of transferred volume and the frequency at which transfers occurred. These different operational modes were analysed to determine changes in nutrient and metal concentrations, chlorophyll a, algal genera and biovolume. During high water transfers, chlorophyll a and total algal biovolume increased, with larger diatoms preferentially selected due to the high silica content of the pumped inflow and a significant shift in cyanobacteria genera occurring from Microcystis to nitrogen-fixing genera. The magnitude and timing of water transfers exerted a strong control on phytoplankton competition and disturbed the typical seasonal succession during low pumping years of a spring diatom bloom followed by summer cyanobacteria dominance: intensive and frequent water transfers resulted in dominance by diatoms for the whole year and effectively limited cyanobacteria summer growth. From this analysis, we identified iron concentration and diatom biovolume as the key water quality indicators to be included in any optimal management, able to control the transfer regime from both a water quantity and water quality prospective. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. Long-term reduction of health care costs & utilization after epilepsy surgery

    PubMed Central

    Schiltz, Nicholas K.; Kaiboriboon, Kitti; Koroukian, Siran M.; Singer, Mendel E.; Love, Thomas E.

    2015-01-01

    SUMMARY Objective To assess long-term direct medical costs, health care utilization, and mortality following resective surgery in persons with uncontrolled epilepsy. Methods Retrospective longitudinal cohort study of Medicaid beneficiaries with epilepsy from 2000 - 2008. The study population included 7,835 persons with uncontrolled focal epilepsy age 18 to 64 years, with an average follow-up time of 5 years. Of these, 135 received surgery during the study period. To account for selection bias, we used risk-set optimal pairwise matching on a time-varying propensity score, and inverse probability of treatment weighting. Repeated measures generalized linear models were used to model utilization and cost outcomes. Cox proportional hazard was used to model survival. Results The mean direct medical cost difference between the surgical group and control group was $6,806 after risk-set matching. The incidence rate ratio of inpatient, emergency room, and outpatient utilization was lower among the surgical group in both unadjusted and adjusted analyses. There was no significant difference in mortality after adjustment. Among surgical cases, mean annual costs per subject were on average $6,484 lower, and all utilization measures were lower after surgery compared to before. Significance Subjects that underwent epilepsy surgery had lower direct medical care costs and health care utilization. These findings support that epilepsy surgery yield substantial health care cost savings. PMID:26693701

  15. Atmospheric verification of anthropogenic CO2 emission trends

    NASA Astrophysics Data System (ADS)

    Francey, Roger J.; Trudinger, Cathy M.; van der Schoot, Marcel; Law, Rachel M.; Krummel, Paul B.; Langenfelds, Ray L.; Paul Steele, L.; Allison, Colin E.; Stavert, Ann R.; Andres, Robert J.; Rödenbeck, Christian

    2013-05-01

    International efforts to limit global warming and ocean acidification aim to slow the growth of atmospheric CO2, guided primarily by national and industry estimates of production and consumption of fossil fuels. Atmospheric verification of emissions is vital but present global inversion methods are inadequate for this purpose. We demonstrate a clear response in atmospheric CO2 coinciding with a sharp 2010 increase in Asian emissions but show persisting slowing mean CO2 growth from 2002/03. Growth and inter-hemispheric concentration difference during the onset and recovery of the Global Financial Crisis support a previous speculation that the reported 2000-2008 emissions surge is an artefact, most simply explained by a cumulative underestimation (~ 9PgC) of 1994-2007 emissions; in this case, post-2000 emissions would track mid-range of Intergovernmental Panel on Climate Change emission scenarios. An alternative explanation requires changes in the northern terrestrial land sink that offset anthropogenic emission changes. We suggest atmospheric methods to help resolve this ambiguity.

  16. Climate Risk and Vulnerability in the Caribbean and Gulf of Mexico Region: Interactions with Spatial Population and Land Cover Change

    NASA Astrophysics Data System (ADS)

    Chen, R. S.; Levy, M.; Baptista, S.; Adamo, S.

    2010-12-01

    Vulnerability to climate variability and change will depend on dynamic interactions between different aspects of climate, land-use change, and socioeconomic trends. Measurements and projections of these changes are difficult at the local scale but necessary for effective planning. New data sources and methods make it possible to assess land-use and socioeconomic changes that may affect future patterns of climate vulnerability. In this paper we report on new time series data sets that reveal trends in the spatial patterns of climate vulnerability in the Caribbean/Gulf of Mexico Region. Specifically, we examine spatial time series data for human population over the period 1990-2000, time series data on land use and land cover over 2000-2009, and infant mortality rates as a proxy for poverty for 2000-2008. We compare the spatial trends for these measures to the distribution of climate-related natural disaster risk hotspots (cyclones, floods, landslides, and droughts) in terms of frequency, mortality, and economic losses. We use these data to identify areas where climate vulnerability appears to be increasing and where it may be decreasing. Regions where trends and patterns are especially worrisome include coastal areas of Guatemala and Honduras.

  17. [Cancer in adolescents and young adults in France: Epidemiology and pathways of care].

    PubMed

    Desandes, Emmanuel; Lacour, Brigitte; Clavel, Jacqueline

    2016-12-01

    In adolescents and young adults (AYA), cancers are rare but represent the third significant cause of death. The aim of this paper was to investigate epidemiological data and pathways of care of AYA in France. During the 2000-2008 period, overall age-standardized incidence rates (ASR) were 254.1/10(6) in 15-24-year-olds. The most frequently diagnosed cancers in male AYA were malignant gonadal germ-cell tumors and Hodgkin's lymphoma, and were melanoma, thyroid carcinoma and Hodgkin's disease in females. The ASR appeared stable over time. During the 2000-2004 period, the 5-year overall survival for all cancers was 81.8%, with differences between genders and age groups: 78.8% for males and 85.2% for females; 78.5% in 15-19-year-olds and 84.3% in 20-24-year-olds. Survival has significantly improved over time. During the 2006-2007 period, the pathways of care for French adolescent patients with cancer were heterogeneous: 82% were treated in an adult environment, 27% were included in clinical studies, and in 54% of cases the management decisions were taken in the context of a multidisciplinary team. Studies looking at management of AYA with cancer have shown a wide disparity and a lack of collaboration between adult oncologists and pediatric oncologist. An AYA cancer multidisciplinary interest group has been created to determine priorities and coordinate efforts to improve AYA cancer services and care.

  18. Analysis of the landscape complexity and heterogeneity of the Pantanal wetland.

    PubMed

    Miranda, C S; Gamarra, R M; Mioto, C L; Silva, N M; Conceição, A P; Pott, A

    2017-08-17

    This is the first report on analysis of habitat complexity and heterogeneity of the Pantanal wetland. The Pantanal encompasses a peculiar mosaic of environments, being important to evaluate and monitor this area concerning conservation of biodiversity. Our objective was to indirectly measure the habitat complexity and heterogeneity of the mosaic forming the sub-regions of the Pantanal, by means of remote sensing. We obtained free images of Normalized Difference Vegetation Index (NDVI) from the sensor MODIS and calculated the mean value (complexity) and standard deviation (heterogeneity) for each sub-region in the years 2000, 2008 and 2015. The sub-regions of Poconé, Canoeira, Paraguai and Aquidauana presented the highest values of complexity (mean NDVI), between 0.69 and 0.64 in the evaluated years. The highest horizontal heterogeneity (NDVI standard deviation) was observed in the sub-region of Tuiuiú, with values of 0.19 in the years 2000 and 2015, and 0.21 in the year 2008. We concluded that the use of NDVI to estimate landscape parameters is an efficient tool for assessment and monitoring of the complexity and heterogeneity of the Pantanal habitats, applicable in other regions.

  19. Research productivity of Pakistan in medical sciences during the period 1996-2012.

    PubMed

    Meo, S A; Almasri, A A; Usmani, A M

    2013-11-01

    This study aimed to investigate the degree of research outcome in medical science subjects in Pakistan during the period 1996-2012. In this study, the research papers published in various global science journals during the period 1996-2012 were accessed. We recorded the total number of research documents having an affiliation with a Pakistan. The main source for information was Institute of Scientific Information (ISI) Web of Science, Thomson Reuters and SCI-mago/Scopus. In global science, Pakistan contributed 58133 research papers in all science and social sciences both in ISI and non ISI indexed journals. However, in medical sciences the total number of research papers from Pakistan are 25604, citable documents 23874, citations 128061, mean citations per documents 6.45 and mean Hirsch index is 35.33. In Pakistan, the upward trend of articles published in global medical science was from the period 1996-2008. However, from 2008 the trend is markedly declined. Pakistan significantly improved its international ranking positions in research during the period 2000-2008. However, the upward trend of research papers published in global medical science could not be retained and from the year 2008 the trend started declining. This trend of research papers further declined in year 2012 compared to year 2011. It is suggested that, Pakistan must take strategic steps to enhance the research culture and increase the research and development expenditure in the country.

  20. Patients with epilepsy are at an increased risk of subsequent stroke: a population-based cohort study.

    PubMed

    Chang, Chen-Shu; Liao, Chun-Hui; Lin, Che-Chen; Lane, Hsien-Yuan; Sung, Fung-Chang; Kao, Chia-Huang

    2014-05-01

    Epilepsy is well known as a disorder in poststroke patients. However, studies that have investigated the association between epilepsy and the risk of subsequent stroke are limited. This population-based study investigated the incidence and risk of stroke in patients with epilepsy by using the Taiwan National Health Insurance claims data. We identified 3812 patients newly diagnosed with epilepsy in 2000-2008 and 15,248 nonepilepsy comparisons frequency matched according to sex, age, and index year. We searched for subsequent stroke diagnoses in both cohorts until the end of 2009. The incidence rates and hazard ratios of stroke were estimated based on sex, age, the average defined daily doses (DDDs) of antiepilepsy drugs, and comorbidity. The stroke incidence of the epilepsy cohort was 3-fold higher than that of the comparison cohort. The age-specific results indicated that in the epilepsy cohort and the comparison cohort, the risk was the highest for the youngest group (20-39 years). The patients with epilepsy exhibited a higher incidence of cerebral stroke than the general population did. In addition, younger patients with epilepsy and patients who took a high doses of antiepileptic drugs exhibited a high risk of stroke. Copyright © 2014 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

  1. Racial residential segregation and preterm birth: built environment as a mediator.

    PubMed

    Anthopolos, Rebecca; Kaufman, Jay S; Messer, Lynne C; Miranda, Marie Lynn

    2014-05-01

    Racial residential segregation has been associated with preterm birth. Few studies have examined mediating pathways, in part because, with binary outcomes, indirect effects estimated from multiplicative models generally lack causal interpretation. We develop a method to estimate additive-scale natural direct and indirect effects from logistic regression. We then evaluate whether segregation operates through poor-quality built environment to affect preterm birth. To estimate natural direct and indirect effects, we derive risk differences from logistic regression coefficients. Birth records (2000-2008) for Durham, North Carolina, were linked to neighborhood-level measures of racial isolation and a composite construct of poor-quality built environment. We decomposed the total effect of racial isolation on preterm birth into direct and indirect effects. The adjusted total effect of an interquartile increase in racial isolation on preterm birth was an extra 27 preterm events per 1000 births (risk difference = 0.027 [95% confidence interval = 0.007 to 0.047]). With poor-quality built environment held at the level it would take under isolation at the 25th percentile, the direct effect of an interquartile increase in isolation was 0.022 (-0.001 to 0.042). Poor-quality built environment accounted for 35% (11% to 65%) of the total effect. Our methodology facilitates the estimation of additive-scale natural effects with binary outcomes. In this study, the total effect of racial segregation on preterm birth was partially mediated by poor-quality built environment.

  2. The climatology of zonal wave numbers 1 and 2 planetary wave structure in the MLT using a chain of Northern Hemisphere SuperDARN radars

    NASA Astrophysics Data System (ADS)

    Kleinknecht, Nora H.; Espy, Patrick J.; Hibbins, Robert E.

    2014-02-01

    The zonal wave components 1 and 2 were extracted from the meridional wind along the latitude band of 51-66°N for the years 2000-2008 using eight Super Dual Auroral Radar Network (SuperDARN) radars spanning longitudes from 25°E to 150°W. Each extracted zonal component represents the superposition of all temporal periods with that zonal structure and indicates the total planetary wave energy available with that wave number. The Hovmöller diagrams show stationary as well as eastward and westward traveling planetary waves propagating in the background wind. The method used to detect the zonal planetary wave components in the SuperDARN data are detailed and validated using UK Meteorological Office data, which allows the evolution of S1 and S2 planetary wave energy between the stratosphere and mesosphere to be assessed. The climatology of zonal wave number 1 and 2 planetary wave activity in the mesosphere-lower thermosphere (MLT) is presented and compared to the activity in the stratosphere. The MLT climatology of the mean wind anomalies shows stronger planetary wave activity during winter and weaker activity during summer with enhancement around midsummer and autumn equinox. The climatology of the mean wind displays similar amplitudes apart from very strong S1 planetary wave amplitudes during summer. In addition planetary wave activity during winters with major and minor stratospheric warming events are examined and contrasted.

  3. Work schedules and health behavior outcomes at a large manufacturer.

    PubMed

    Bushnell, P Timothy; Colombi, Alberto; Caruso, Claire C; Tak, Sangwoo

    2010-01-01

    There is evidence that work schedules may influence rates of unhealthy behaviors, suggesting that addressing work schedule challenges may improve health. Health Risk Assessment (HRA) survey responses were collected during 2000-2008 in a multinational chemical and coatings manufacturer. Responses of 26,442 were sufficiently complete for analysis. Rates of smoking, lack of exercise, moderate to high alcohol use, obesity (BMI > or = 30), and short sleep duration were compared by work schedule type (day, night, or rotating shift) and daily work hours (8, 10, or 12 h). Prevalence rate ratios (RRs) were calculated, adjusting for age group, sex, marital/living status, job tenure, and occupational group. The reference group was 8-h day shift employees. Overall prevalence rates were: sleep duration of 6 h or less per night 47%, smoking 17.3%, no exercise 22.0%, BMI > or = 30 28.3%, and moderate to heavy alcohol consumption 22.2%. Statistically significant RRs include the following: Short sleep duration: 10 h rotating shift (RR=1.6), 12 h day and 12 h rotating shifts (RR=1.3); Smoking: 12 h day and rotating shifts (RR=1.6), 10 and 12 h night and 8 h rotating shift (RR=1.4); No exercise: 8, 10, and 12 h rotating shifts (RR=1.2 to 1.3), 12 h day schedules (RR=1.3). Obesity (BMI > or = 30): 8 and 10 h night shifts (RR=1.3 and 1.4, respectively).

  4. Correlation of blood pressure readings from 6-hour intervals with the daytime period of 24-hour ambulatory blood pressure monitoring in pediatric patients.

    PubMed

    King-Schultz, Leslie; Weaver, Amy L; Cramer, Carl H

    2012-06-01

    Shorter-interval (6-hour) ambulatory blood pressure monitoring (ABPM) has been shown to correlate well with 24-hour ABPM in adults, but this has not been studied in children. The authors selected 131 patients aged 9 to 18 who underwent 24-ABPM from 2000-2008. Six-hour intervals beginning at different start times were compared with the daytime and 24-hour period, with subset analysis for normotensive and hypertensive patients. Concordance correlation coefficients (CCCs) were used to assess for agreement. Among normotensive patients, the mean difference between daytime and 6-hour intervals ranged from -0.1 mm Hg to 0.0 mm Hg for diastolic blood pressure (DBP) and -1.1 mm Hg to 0.6 mm Hg for systolic blood pressure (SBP) with CCCs of 0.88 to 0.93 for DBP and 0.93 to 0.96 for SBP. For hypertensive patients, mean difference ranged from -0.6 to 1.3 mm Hg for DBP and -0.8 to 1.1 mm Hg for SBP with CCCs of 0.89 to 0.98 for DBP and 0.86 to 0.95 for SBP. Shorter-interval monitoring correlates significantly with full daytime monitoring in children, allowing for assessment of blood pressure with improved convenience. © 2012 Wiley Periodicals, Inc.

  5. Human development report 2010: Changes in parameters and perspectives.

    PubMed

    Rahi, Manju

    2011-01-01

    Human Development Report (HDR) 2010 in its 20 th year contains several significant changes. Indicators to measure the three dimensions of Human Development Index (HDI) have been changed: Gender-related Development Index (GDI) and Gender Empowerment Index have been replaced by Gender Inequality Index (GII) and Human Poverty Index has been replaced by Multi-dimensional Poverty Index. Inequality-adjusted HDI (IHDI) has been introduced for the first time. Between 1980 and 2010, India's HDI rose by 1.6% annually from 0.320 to 0.519. While India's HDI value has improved over time, the rank has not improved as much as compared to other developing countries. On GII, India ranked at 122 with a GII value of 0.748 (ranges between 0 and 1) in 2010 HDR (based on data of 2008), revealing considerable loss in achievements in three dimensions of human development - reproductive health, empowerment, and labor market - due to inequality between genders. Multi-dimensional Poverty Index was 0.296 (2000-2008) and IHDI was 0.365 (2000-2007).

  6. An individual-based model of the krill Euphausia pacifica in the California Current

    NASA Astrophysics Data System (ADS)

    Dorman, Jeffrey G.; Sydeman, William J.; Bograd, Steven J.; Powell, Thomas M.

    2015-11-01

    Euphausia pacifica is an abundant and important prey resource for numerous predators of the California Current and elsewhere in the North Pacific. We developed an individual-based model (IBM) for E. pacifica to study its bioenergetics (growth, stage development, reproduction, and mortality) under constant/ideal conditions as well as under varying ocean conditions and food resources. To model E. pacifica under varying conditions, we coupled the IBM to an oceanographic-ecosystem model over the period 2000-2008 (9 years). Model results under constant/ideal food conditions compare favorably with experimental studies conducted under food unlimited conditions. Under more realistic variable oceanographic conditions, mean growth rates over the continental shelf were positive only when individuals migrated diurnally to the depth of maximum phytoplankton layer during nighttime feeding. Our model only used phytoplankton as prey and coastal growth rates were lower than expected (0.01 mm d-1), suggesting that a diverse prey base (zooplankton, protists, marine snow) may be required to facilitate growth and survival of modeled E. pacifica in the coastal environment. This coupled IBM-ROMS modeling framework and its parameters provides a tool for understanding the biology and ecology of E. pacifica and could be developed to further the understanding of climatic effects on this key prey species and enhance an ecosystem approach to fisheries and wildlife management in this region.

  7. [Dietary factors and their relation to appetite in children under two years with mild malnutrition].

    PubMed

    Quijada, Mariana Martínez; Gutiérrez, María Luisa Alvarez

    2012-06-01

    Malnutrition is conditioned by a series of factors, among them the dietary factors, which include appetite, eating behaviors and habits. In order to assess these factors, the following objective was pursued: describe the dietary factors and their relation to appetite in children under two years of age with mild malnutrition. A correlational study was conducted. The sample consisted of all children under two years of age (n = 168) diagnosed with primary (mild) malnutrition, who attended consultation at the Centro de Atención Nutricional Infantil Antímano, CANIA, during the period 2000-2008. The results showed intake of energy and macronutrients was lower than the individual requirement; iron intake < 85% of the requirement, in accordance with the Recommended Dietary Allowances (RDA) in over 50% of the sample; weekly consumption of vegetables (57%) and miscellaneous (66%) was inadequate; inadequate intake of formula and whole milk in more than 60%; 9% were exclusively breastfed during the first six months; 64% lacked a regular eating place; in child-caregiver interaction during mealtimes, more than half of the children showed rebellious behavior and caregivers were permissive. Protein adequacy, vegetable and whole milk consumption frequency, preparation type, identification of refusals and preferences, place and duration of meals, and child-caregiver interaction at mealtimes were significantly associated with appetite; if we consider this last one as a guide and we try to modify inadequate eating behaviors and habits, we will generate an impact over the child appetite that could improve the food consumption and prevent malnutrition.

  8. Assessing groundwater quality in Greece based on spatial and temporal analysis.

    PubMed

    Dokou, Zoi; Kourgialas, Nektarios N; Karatzas, George P

    2015-12-01

    The recent industrial growth together with the urban expansion and intensive agriculture in Greece has increased groundwater contamination in many regions of the country. In order to design successful remediation strategies and protect public health, it is very important to identify those areas that are most vulnerable to groundwater contamination. In this work, an extensive contamination database from monitoring wells that cover the entire Greek territory during the last decade (2000-2008) was used in order to study the temporal and spatial distribution of groundwater contamination for the most common and serious anionic and cationic trace element pollutants (heavy metals). Spatial and temporal patterns and trends in the occurrence of groundwater contamination were also identified highlighting the regions where the higher groundwater contamination rates have been detected across the country. As a next step, representative contaminated aquifers in Greece, which were identified by the above analysis, were selected in order to analyze the specific contamination problem in more detail. To this end, geostatistical techniques (various types of kriging, co-kriging, and indicator kriging) were employed in order to map the contaminant values and the probability of exceeding critical thresholds (set as the parametric values of the contaminant of interest in each case). The resulting groundwater contamination maps could be used as a useful tool for water policy makers and water managers in order to assist the decision-making process.

  9. Machine Learning: Proceedings of the Fifteenth International Conference

    DTIC Science & Technology

    1998-07-01

    example, the dilemma of Buridan’s ass.1 This poor animal is placed at equal distances away from two platefuls of food. He is hun- gry so he feels like...ass in his extant writings, but this concept was invented by his opponents to ridicule his use of animals in the examples he used to expound his...hay que desplegar mayores esfuerzos para coordinar las actividades de los sectores publico y privado. La experiencia adquirida du- rante este

  10. The Contribution of the Spanish Guardia Civil to the Peace and Stability Operations Within the Human Security Framework

    DTIC Science & Technology

    2010-03-08

    teams of two officers ( parejas ) as established in its famous Code of Practice. These teams composed of two officers were responsible for patrolling...internacionals/nwn 76 seguridad humana conceptos experiencias y___propuestas (accessed October 26, 2009). Gray, Colin S. Another Bloody Century. London...Affairs, 76 (February 2007): 47-58, http://www.cidob.org/es/publicaciones/revistas/revista cidob d afers intemacionals/num 76 seguridad humana conceptos

  11. [Screening and early care programmes in children with autism spectrum disorders].

    PubMed

    Canal-Bedia, Ricardo; García-Primo, Patricia; Santos-Borbujo, José; Bueno-Carrera, Gloria; Posada-De la Paz, Manuel

    2014-02-24

    Introduccion. La necesidad de la deteccion y de tratamientos eficaces de forma temprana para los trastornos del espectro autista es algo actualmente aceptado tanto por las sociedades profesionales como por la administracion sanitaria. Una informacion actualizada y sintetizada sobre los procedimientos de cribado y las tecnicas de atencion temprana para niños con trastornos del espectro autista facilitara la puesta en marcha de mejores dispositivos de deteccion y la labor de asesoramiento a familias y profesionales sobre la atencion e intervencion a edades tempranas de los niños. Desarrollo. Se proporciona una revision actualizada de los procedimientos de deteccion precoz y de atencion temprana en el autismo, reflejando los aspectos mas relevantes que se deducen de las experiencias y estudios llevados a cabo hasta el momento. Conclusiones. Tras la revision realizada sobre las experiencias de deteccion precoz de autismo, se obtiene un grupo de consideraciones importantes para realizar analisis criticos de programas de cribado en marcha, asi como recomendaciones para experiencias futuras. La revision sobre los programas de atencion temprana proporciona una vision esperanzadora porque cada vez son mas frecuentes, sistematicos y metodologicamente mas apropiados los estudios sobre la eficacia de los programas de atencion temprana.

  12. Observed Nordic Sea ice-cover variability 1992-2008

    NASA Astrophysics Data System (ADS)

    Kern, Stefan; Kaleschke, Lars; Spreen, Gunnar

    We examined the sea-ice cover of the Arctic peripheral seas bordering the Northern North Atlantic: Irminger, Greenland, Barents, Kara, and White/Pechora Sea using daily sea-ice con-centration data obtained with the ASI algorithm at a grid resolution of 12.5 km × 12.5 km from Special Sensor Microwave/Imager 85 GHz brightness temperature measurements for 1992-2008. The obtained annual cycles of monthly average ice area and extent indicate, in agreement with previous studies, an increase of the length of the melt season and reductions in the mean maxi-mum and minimum ice-cover in all regions between 1992-1999 and 2000-2008, with wintertime changes of between 5-10% (Greenland Sea, White/Pechora Sea) and 15-20% (Irminger and Barents Sea), and summertime changes between 30% (Kara Sea) and up to 55% (Irminger and Barents Sea). Monthly mean ice-area and -extent anomalies relative to the average annual cycle are calculated and indicate pronounced differences between the Barents Sea and the other regions. A lag-correlation analysis between all ice-area and -extent anomalies is carried out. The main results are: i) Barents Sea ice-area and -extent anomalies are significantly auto-correlated for a two-fold longer period of time than respective anomalies in the other regions. ii) Fall/early winter Irminger Sea ice-area and -extent anomalies are significantly correlated with respective summer/fall Greenland Sea anomalies; the average time-lag is 2-3 months, the average (max-imum) duration is 2 (8) months. iii) Barents and Kara Sea ice-area and -extent anomalies are significantly correlated with each other during summer/fall. We found also a significant correlation between Barents Sea Dec. to July and Kara Sea July to Sep./Nov. ice-area and -extent anomalies with an average duration of 2-3 months. We have investigated the relationship between anomalies in ice-area flux between the Arctic Ocean and the considered peripheral seas and the ice-area and -extent anomalies in these

  13. Greenland ice sheet outlet glacier front changes: comparison of year 2008 with past years

    NASA Astrophysics Data System (ADS)

    Decker, D. E.; Box, J.; Benson, R.

    2008-12-01

    NASA's Moderate Resolution Imaging Spectroradiometer (MODIS) imagery are used to calculate inter-annual, end of summer, glacier front area changes at 10 major Greenland ice sheet outlets over the 2000-2008 period. To put the recent 8 end of summer net annual changes into a longer perspective, glacier front position information from the past century are also incorporated. The largest MODIS-era area changes are losses/retreats; found at the relatively large Petermann Gletscher, Zachariae Isstrom, and Jakobshavn Isbrae. The 2007-2008 net ice area losses were 63.4 sq. km, 21.5 sq. km, and 10.9 sq. km, respectively. Of the 10 largest Greenland glaciers surveyed, the total net cumulative area change from end of summer 2000 to 2008 is -536.6 sq km, that is, an area loss equivalent with 6.1 times the area of Manhattan Is. (87.5 sq km) in New York, USA. Ice front advances are evident in 2008; also at relatively large and productive (in terms of ice discharge) glaciers of Helheim (5.7 sq km), Store Gletscher (4.9 sq km), and Kangerdlugssuaq (3.4 sq km). The largest retreat in the 2000-2008 period was 54.2 sq km at Jakobshavn Isbrae between 2002 and 2003; associated with a floating tongue disintegration following a retreat that began in 2001 and has been associated with thinning until floatation is reached; followed by irreversible collapse. The Zachariae Isstrom pro-glacial floating ice shelf loss in 2008 appears to be part of an average ~20 sq km per year disintegration trend; with the exception of the year 2006 (6.2 sq km) advance. If the Zachariae Isstrom retreat continues, we are concerned the largest ice sheet ice stream that empties into Zachariae Isstrom will accelerate, the ice stream front freed of damming back stress, increasing the ice sheet mass budget deficit in ways that are poorly understood and could be surprisingly large. By approximating the width of the surveyed glacier frontal zones, we determine and present effective glacier normalized length (L

  14. Review of 40-year MD theses in medical oncology.

    PubMed

    Zeeneldin, Ahmed; Diyaa, Amira; Moneer, Manar; Elgammal, Mosaad; Buhoush, Wafa

    2014-09-01

    It is almost 40 years since the foundation of the Medical Oncology (MO) Department. We aimed to appraise the clinical research to fulfill the Medical Doctorate (MD) degree in MO at the National Cancer Institute, Cairo University (NCI, CU). This review included 62 MD theses containing 66 studies. They were reviewed regarding aims, type of study, clinical trial phase, design and methodology, statistical tests, results, limitations, consent and IRB approval. Theses were grouped into 3 periods: 1970-1989, 1990-1999 and 2000-2008. Almost 76% of the studies were interventional and 24% were observational. Informed consent and Institutional Review Board approval were mentioned in 18 and 2 studies, respectively. While all studies mentioned the aims, none, clearly mentioned the research question. Outcomes were mainly efficacy followed by safety. Study design was inadequately considered, especially in 70's-80's period (p=0.038). Median sample size and study duration were almost stable through the three periods (p=0.441, 0.354, respectively). Most of the studies used both descriptive and analytical statistical methods. In a descending order, researched cancers were lymphoma, breast, leukemia, liver, urinary bladder, lung and colorectal. The commonest stages researched were IV and III. The number of studies focused on assessing biomarkers, biomarkers plus drugs/procedures, drugs and procedures are 20, 20, 16 and 6, respectively. With time, research within MD theses in MO increased quantitatively and qualitatively. Improvements were noticeable in documentation of study design. Copyright © 2014. Production and hosting by Elsevier B.V.

  15. New legal protections for reporting patient errors under the Patient Safety and Quality Improvement Act: a review of the medical literature and analysis.

    PubMed

    Howard, Jeff; Levy, Fred; Mareiniss, Darren P; Patch, Michelle; Craven, Catherine K; McCarthy, Melissa; Epstein-Peterson, Zachary Drew; Wong, Victoria; Pronovost, Peter

    2010-09-01

    The Patient Safety and Quality Improvement Act (PSQIA) of 2005, inspired by the Institute of Medicine's (IOM) 1999 report To Err Is Human, affords federal protections in exchange for error disclosures. However, the PSQIA is unlikely to be effective unless frontline providers are aware of its existence. In this study, we assessed the quantity of publications regarding this protection within the medical literature. Four reviewers independently evaluated 2060 safety-related articles, identified through a PubMed database search, to determine whether they discussed actual (or proposed) national legal protections for voluntary reporting of medical errors. Using a reviewer method based on a standard Delphi consensus model, agreement was achieved if at least 3 of 4 reviewers agreed with the decision. Articles were separated into pre-IOM report (1990-1999) and post-IOM report (2000-2008) literature. No articles were determined to be "on topic" in the pre-IOM period (n = 624). Twenty-seven articles were considered "on topic" in the post-IOM period (n = 1436), constituting 1.8% of the period total (95% confidence interval, 1.2%-2.6%). Of the 27 on topic articles, 7 appeared in practice-related journals, whereas the remaining 20 were in journals with a health policy or health care administration focus. Few published studies were found in clinical journals describing the PSQIA. This raises serious concerns and indicates that physicians may not be aware of the new legal protections afforded for error disclosure. If the health care system is to realize the benefits of error reporting systems, greater education of physicians regarding their legal protections may be needed.

  16. Using long-term water balances to parameterize surface conductances and calculate evaporation at 0.05° spatial resolution

    NASA Astrophysics Data System (ADS)

    Zhang, Yongqiang; Leuning, Ray; Hutley, Lindsay B.; Beringer, Jason; McHugh, Ian; Walker, Jeffrey P.

    2010-05-01

    Evaporation from the land surface, averaged over successive 8 day intervals and at 0.05° (˜5 km) spatial resolution, was calculated using the Penman-Monteith (PM) energy balance equation, gridded meteorology, and a simple biophysical model for surface conductance. This conductance is a function of evaporation from the soil surface, leaf area index, absorbed photosynthetically active radiation, atmospheric water vapor pressure deficit, and maximum stomatal conductance (gsx). The novelty of this paper is the use of a "Budyko-curve" hydrometeorological model to estimate mean annual evaporation rates and hence a unique value of gsx for each grid cell across the Australian continent. First, the hydrometeorological model was calibrated using long-term water balances from 285 gauged catchments. Second, gridded meteorological data were used with the calibrated hydrometeorological model to estimate mean annual average evaporation (?) for each grid cell. Third, the value of gsx for each cell was adjusted to equate ? calculated using the PM equation with ? from the hydrometeorological model. This closes the annual water balance but allows the PM equation to provide a finer temporal resolution for evaporation than is possible with an annual water balance model. There was satisfactory agreement (0.49 < R2 < 0.80) between 8 day average evaporation rates obtained using remotely sensed leaf area indices, the parameterized PM equation, and observations of actual evaporation at four Australian eddy covariance flux sites for the period 2000-2008. The evaporation product can be used for hydrological model calibration to improve runoff prediction studies in ungauged catchments.

  17. Heat-related deaths in hot cities: estimates of human tolerance to high temperature thresholds.

    PubMed

    Harlan, Sharon L; Chowell, Gerardo; Yang, Shuo; Petitti, Diana B; Morales Butler, Emmanuel J; Ruddell, Benjamin L; Ruddell, Darren M

    2014-03-20

    In this study we characterized the relationship between temperature and mortality in central Arizona desert cities that have an extremely hot climate. Relationships between daily maximum apparent temperature (ATmax) and mortality for eight condition-specific causes and all-cause deaths were modeled for all residents and separately for males and females ages <65 and ≥ 65 during the months May-October for years 2000-2008. The most robust relationship was between ATmax on day of death and mortality from direct exposure to high environmental heat. For this condition-specific cause of death, the heat thresholds in all gender and age groups (ATmax = 90-97 °F; 32.2-36.1 °C) were below local median seasonal temperatures in the study period (ATmax = 99.5 °F; 37.5 °C). Heat threshold was defined as ATmax at which the mortality ratio begins an exponential upward trend. Thresholds were identified in younger and older females for cardiac disease/stroke mortality (ATmax = 106 and 108 °F; 41.1 and 42.2 °C) with a one-day lag. Thresholds were also identified for mortality from respiratory diseases in older people (ATmax = 109 °F; 42.8 °C) and for all-cause mortality in females (ATmax = 107 °F; 41.7 °C) and males <65 years (ATmax = 102 °F; 38.9 °C). Heat-related mortality in a region that has already made some adaptations to predictable periods of extremely high temperatures suggests that more extensive and targeted heat-adaptation plans for climate change are needed in cities worldwide.

  18. Two Decades of Seismic Monitoring by WEBNET: Disclosing a Lifecycle of an Earthquake Swarm Zone

    NASA Astrophysics Data System (ADS)

    Fischer, T.; Horalek, J.; Cermakova, H.; Michalek, J.; Doubravova, J.; Bouskova, A.; Bachura, M.

    2014-12-01

    The area of West Bohemia/Vogtland in western Eger Rift is typified by earthquake swarm activity with maximum magnitudes not exceeding ML 5. The seismicity is dominated by the area near Novy Kostel where earthquakes cluster along a narrow and steeply dipping focal zone of 8 km length that strikes about N-S in the depth range 7-11 km. Detailed seismic monitoring has been carried out by the WEBNET seismic network since 1992. During that period earthquake swarms with several mainshocks exceeding magnitude level ML 3 took place in 2000, 2008 and 2011. These swarms were characteristic by episodic character where the activity of individual episodes overlapped in time and space. Interestingly, the rate of activity of individual swarms increased with each subsequent swarm; the 2000 swarm being the slowest and the 2011 swarm the most rapid one. In 2014 the character of seismicity has changed from a swarm-like activity to a mainshock-aftershock activity. Already three mainshocks has occurred since May 2014; the ML 3.6 event of May 24, the ML 4.5 event of May 31 and the ML 3.5 event of August 3. All these events were followed by a short aftershock sequence of one to four days duration. All three events exceeded the following aftershocks by more than one magnitude level and none of these mainshocks were preceded by foreshocks, which differentiates this activity from the preceding swarm seismicity. Interestingly, the hypocenters of the mentioned earthquake swarms and mainshock-aftershock sequences share a common fault zone and overlap significantly. We present detailed analysis of precise hypocenter locations and statistical characteristics of the activity in order to find the origin of different behavior of seismic activity, which results in either earthquake swarms or mainshock-aftershock activity.

  19. Anaplasmosis and ehrlichiosis - Maine, 2008.

    PubMed

    2009-09-25

    Anaplasmosis and ehrlichiosis are rickettsial tickborne diseases that have had at least a twofold increase in prevalence in the United States since 2000. Despite similar clinical presentations, the causative organisms are carried by different ticks with distinct geographic and ecologic associations. Surveillance efforts are complicated by ambiguous terminology and serologic testing with antibody cross-reactivity. Although anaplasmosis historically has been reported in Maine, ehrlichiosis has been reported infrequently. During 2007-2008, the number of physician-reported anaplasmosis cases nearly doubled in Maine, and ehrlichiosis cases increased more than fourfold. To examine this increase, the Maine Department of Health and Human Services (MDHHS) analyzed available data on tick burden and physician-reported cases of anaplasmosis and ehrlichiosis during 2000-2008. This report describes the results of that analysis, which indicated that Ixodes scapularis (the tick vector for Anaplasma phagocytophilum) was broadly distributed in Maine, whereas Amblyomma americanum (the tick vector for Erhlichia chaffeenisis) was scarce. Moreover, 95% of physician-reported ehrlichiosis cases lacked a concurrent serologic assessment to exclude anaplasmosis, suggesting that antibody cross-reactivity might have resulted in misclassification. In 2008, Maine modified case classification to enhance specificity; ehrlichiosis cases that lack a concurrent test for anaplasmosis are now classified as suspect rather than probable and therefore are not included in national surveillance summaries. The accuracy of case classification and surveillance can be improved by educating health-care providers regarding 1) the expected geographic distribution of tick vectors and 2) recommendations for confirmatory testing to distinguish between the causative organisms of anaplasmosis and ehrlichiosis.

  20. Assessment of ecological security in Changbai Mountain Area, China based on MODIS data and PSR model

    NASA Astrophysics Data System (ADS)

    Huang, Fang; Wang, Ping; Qi, Xin

    2014-11-01

    The assessment of ecological security is to identify the stability of the ecosystem, and to distinguish the capacity of sustainable health and integrity under different kinds of risks. Using MODIS time series images from 2000 to 2008 as the main data source, the derived parameters including NDVI, the ratio of NPP and GPP, forest coverage, landscape diversity and ecological flexibility etc. are integrated to depict the properties of the ecological system. The pressure and response indicators such as population density, industrial production intensity, arable land per capita, fertilizer consumption, highway density, agricultural mechanization level and GDP per capita are also collected and managed by ArcGIS. The `pressure-state-response' (PSR) conceptual model and a hierarchical weighted model are applied to construct an evaluation framework and determine the state of ecological security in Changbai Mountain area. The results show that the ecological security index (ESI) values in 2000 and 2008 were 5.75 and 5.59 respectively, indicating the ecological security state in Changbai Mountain area degraded. In 2000, the area of in good state of ecological security was 21901km2, occupying 28.96% of the study region. 48201 km2 of the land were with moderate level. The grades of ESI in Dunhua, Longjing and Antu decreased from moderate to poor. Though the ESI value of Meihekou increased by 0.12 during 2000-2008, it was still in a very poor state of ecological security induced by intensive human activities. The ecological security situation of Changbai Mountain region was not optimistic on the whole.

  1. Public social monitoring reports and their effect on a policy programme aimed at addressing the social determinants of health to improve health equity in New Zealand.

    PubMed

    Pega, Frank; Valentine, Nicole B; Matheson, Don; Rasanathan, Kumanan

    2014-01-01

    The important role that monitoring plays in advancing global health is well established. However, the role of social monitoring as a tool for addressing social determinants of health (SDH) and health equity-focused policies remains under-researched. This paper assesses the extent and ways in which New Zealand's (NZ) Social Reports (SRs) supported a SDH- and health equity-oriented policy programme nationally over the 2000-2008 period by documenting the SRs' history and assessing its impact on policies across sectors in government and civil society. We conducted key-informant interviews with five senior policy-makers and an e-mail survey with 24 government and civil society representatives on SRs' history and policy impact. We identified common themes across these data and classified them accordingly to assess the intensity of the reports' use and their impact on SDH- and health equity-focused policies. Bibliometric analyses of government publications and media items were undertaken to empirically assess SRs' impact on government and civil society. SRs in NZ arose out of the role played by government as the "benevolent social welfare planner" and an understanding of the necessity of economic and social security for "progress". The SRs were linked to establishing a government-wide programme aimed at reducing inequalities. They have been used moderately to highly in central and local government and in civil society, both within and outside the health sector, but have neither entered public treasury and economic development departments nor the commercial sector. The SRs have not reached the more universal status of economic indicators. However, they have had some success at raising awareness of, and have stimulated isolated action on, SDH. The NZ case suggests that national-level social monitoring provides a valuable tool for raising awareness of SDH across government and civil society. A number of strategies could improve social reports' effectiveness in stimulating

  2. Remote-sensing-based analysis of landscape change in the desiccated seabed of the Aral Sea--a potential tool for assessing the hazard degree of dust and salt storms.

    PubMed

    Löw, F; Navratil, P; Kotte, K; Schöler, H F; Bubenzer, O

    2013-10-01

    With the recession of the Aral Sea in Central Asia, once the world's fourth largest lake, a huge new saline desert emerged which is nowadays called the Aralkum. Saline soils in the Aralkum are a major source for dust and salt storms in the region. The aim of this study was to analyze the spatio-temporal land cover change dynamics in the Aralkum and discuss potential implications for the recent and future dust and salt storm activity in the region. MODIS satellite time series were classified from 2000-2008 and change of land cover was quantified. The Aral Sea desiccation accelerated between 2004 and 2008. The area of sandy surfaces and salt soils, which bear the greatest dust and salt storm generation potential increased by more than 36 %. In parts of the Aralkum desalinization of soils was found to take place within 4-8 years. The implication of the ongoing regression of the Aral Sea is that the expansion of saline surfaces will continue. Knowing the spatio-temporal dynamics of both the location and the surface characteristics of the source areas for dust and salt storms allows drawing conclusions about the potential hazard degree of the dust load. The remote-sensing-based land cover assessment presented in this study could be coupled with existing knowledge on the location of source areas for an early estimation of trends in shifting dust composition. Opportunities, limits, and requirements of satellite-based land cover classification and change detection in the Aralkum are discussed.

  3. Modeling the Surface Water-Groundwater Interaction in Arid and Semi-Arid Regions Impacted by Agricultural Activities

    NASA Astrophysics Data System (ADS)

    Tian, Y.; Wu, B.; Zheng, Y.

    2013-12-01

    In many semi-arid and arid regions, interaction between surface water and groundwater plays an important role in the eco-hydrological system. The interaction is often complicated by agricultural activities such as surface water diversion, groundwater pumping, and irrigation. In existing surface water-groundwater integrated models, simulation of the interaction is often simplified, which could introduce significant simulation uncertainty under certain circumstance. In this study, GSFLOW, a USGS model coupling PRMS and MODFLOW, was improved to better characterize the surface water-groundwater interaction. The practices of water diversion from rivers, groundwater pumping and irrigation are explicitly simulated. In addition, the original kinematic wave routing method was replaced by a dynamic wave routing method. The improved model was then applied in Zhangye Basin (the midstream part of Heihe River Baisn), China, where the famous 'Silk Road' came through. It is a typical semi-arid region of the western China, with extensive agriculture in its oasis. The model was established and calibrated using the data in 2000-2008. A series of numerical experiments were conducted to evaluate the effect of those improvements. It has been demonstrated that with the improvements, the observed streamflow and groundwater level were better reproduced by the model. The improvements have a significant impact on the simulation of multiple fluxes associated with the interaction, such as groundwater discharge, riverbed seepage, infiltration, etc. Human activities were proved to be key elements of the water cycle in the study area. The study results have important implications to the water resources modeling and management in semi-arid and arid basins.

  4. Investigating the effects of side airbag deployment in real-world crashes using crash comparison techniques.

    PubMed

    Loftis, Kathryn L; Weaver, Ashley A; Stitzel, Joel D

    2011-01-01

    The objective of this study was to investigate side airbag (SAB) deployment in near side crashes and compare injuries and contact points between occupants with and without SAB deployment. Using NASS 2000-2008 and selecting for near side cases, with PDOF ± 20 degrees from 90 or 270, for non-pregnant adult belted occupants, there were 20,253 (weighted) SAB deployments. NASS showed that SABs have been increasing within the fleet, comprising 2% of airbags in 2000 and increasing to 33% of airbags in 2008. To investigate deployed SABs, we developed a three-step methology to pair CIREN cases to study the effects of deployment on occupant outcome. The first step involved extracting near side impacts from CIREN with adult, non-pregnant occupants seated in row 1 (drivers or right front passengers). In the second step, each case was quantitatively compared to FMVSS 214 barrier test standards using a 6 point similarity scoring system. Cases scoring at least 3 points were then qualitatively analyzed and 33 pairs of cases of the same vehicle make/model but opposite SAB status were chosen. Occupants with deployed SAB had reduced occurrences and severity of head and face, neck and cervical spine, and thoracic injuries and fewer injurious contacts to side components including the door, a-pillar, and window sill. SAB deployment was statistically significant for reducing occupant MAIS and ISS and thorax airbags were statistically significant for reducing thoracic and neck/cervical spine injury severity. The average ISS with SAB deployment was 21, while the average ISS of those without was 33. This study establishes methods for performing comparisons between CIREN cases based on regulatory conditions and shows injury reduction in key body regions with SAB deployment.

  5. On the interest of positive degree day models for mass balance modeling in the inner tropics

    NASA Astrophysics Data System (ADS)

    Maisincho, L.; Favier, V.; Wagnon, P.; Basantes Serrano, R.; Francou, B.; Villacis, M.; Rabatel, A.; Mourre, L.; Jomelli, V.; Cáceres, B.

    2014-05-01

    A positive degree-day (PDD) model was tested on Antizana Glacier 15α (0.28 km2; 0°28' S, 78°09' W) to assess to what extent this approach is suitable for studying glacier mass balance in the inner tropics. Cumulative positive temperatures were compared with field measurements of melting amount and with surface energy balance computations. A significant link was revealed when a distinction was made between the snow and ice comprising the glacier surface. Significant correlations allowed degree-day factors to be retrieved for snow, and clean and dirty ice. The relationship between melt amount and temperature was mainly explained by the role of net shortwave radiation in both melting and in the variations in the temperature of the surface layer. However, this relationship disappeared from June to October (Period 1), because high wind speeds and low humidity cause highly negative turbulent latent heat fluxes. However, this had little impact on the computed total amount of melting at the annual time scale because temperatures are low and melting is generally limited during Period 1. At the daily time scale, melting starts when daily temperature means are still negative, because around noon incoming shortwave radiation is very high, and compensates for energy losses when the air is cold. The PDD model was applied to the 2000-2008 period using meteorological inputs measured on the glacier foreland. Results were compared to the glacier-wide mass balances measured in the field and were good, even though the melting factor should be adapted to the glacier surface state and may vary with time. Finally, the model was forced with precipitation and temperature data from the remote Izobamba station and NCEP-NCAR reanalysis data, also giving good results and showing that temperature variations are homogenous at the regional scale, meaning glacier mass balances can be modelled over large areas.

  6. Impact of rotavirus vaccination on childhood gastroenteritis-related mortality and hospital discharges in Panama.

    PubMed

    Bayard, Vicente; DeAntonio, Rodrigo; Contreras, Rodolfo; Tinajero, Olga; Castrejon, Maria Mercedes; Ortega-Barría, Eduardo; Colindres, Romulo E

    2012-02-01

    Rotavirus vaccination was introduced in Panama in March 2006. This study was carried out in order to describe the trends in gastroenteritis-related (GER) hospitalizations and mortality in children <5 years of age during the pre- and post-vaccination periods. Data from the Expanded Program on Immunization (Ministry of Health) were used to calculate vaccine coverage. GER mortality and hospitalizations were obtained through database review of the Contraloría General de la República and hospital discharge databases of five sentinel hospitals, for the period 2000-2008. Mean rates of GER mortality and mean numbers of hospitalizations during the baseline pre-vaccination period (2000-2005) were compared to those of 2007 and 2008. National coverage for the second rotavirus vaccine dose increased from 30% in 2006 to 62% in 2007 and 71% in 2008, varying from 62% in the West region to 77% in the Panama region. Overall, at 2-years post-vaccine introduction, the GER mortality rate in Panama had decreased by 50% (95% confidence interval (CI) 46-54). During 2000-2005, the GER mortality rate in children (<1 year) was 73/100 000, decreasing by 45% (95% CI 40-51) in 2008. In children aged 1-4 years, the GER mortality rate was 20.3/100 000 (2000-2005), decreasing by 54% (95% CI 48-60) in 2008. The Panama region registered the highest mortality rate reduction (69%; 95% CI 58-81) for 2008. During 2008, GER hospitalizations among children <5 years of age decreased by 30% (95% CI 21-37) from the mean number of hospitalizations during 2000-2005. A substantial reduction in GER mortality and hospitalizations was observed following the introduction of rotavirus vaccine in Panama. Copyright © 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  7. Toward a National Early Warning System for Forest Disturbances Using Remotely Sensed Land-Surface Phenology

    NASA Astrophysics Data System (ADS)

    Hargrove, W. W.; Spruce, J.

    2010-12-01

    recovery in LSP, presumably due to refoliation. 2009 Vegetation Disturbances mapped as percent change in max NDVI from June 10 - July 27 2000-2008

  8. Long-term patterns and short-term dynamics of stream solutes and suspended sediment in a rapidly weathering tropical watershed

    USGS Publications Warehouse

    Shanley, James B.; McDowell, William H.; Stallard, Robert F.

    2011-01-01

    The 326 ha Río Icacos watershed in the tropical wet forest of the Luquillo Mountains, northeastern Puerto Rico, is underlain by granodiorite bedrock with weathering rates among the highest in the world. We pooled stream chemistry and total suspended sediment (TSS) data sets from three discrete periods: 1983-1987, 1991-1997, and 2000-2008. During this period three major hurricanes crossed the site: Hugo in 1989, Hortense in 1996, and Georges in 1998. Stream chemistry reflects sea salt inputs (Na, Cl, and SO4), and high weathering rates of the granodiorite (Ca, Mg, Si, and alkalinity). During rainfall, stream composition shifts toward that of precipitation, diluting 90% or more in the largest storms, but maintains a biogeochemical watershed signal marked by elevated K and dissolved organic carbon (DOC) concentration. DOC exhibits an unusual "boomerang" pattern, initially increasing with flow but then decreasing at the highest flows as it becomes depleted and/or vigorous overland flow minimizes contact with watershed surfaces. TSS increased markedly with discharge (power function slope 1.54), reflecting the erosive power of large storms in a landslide-prone landscape. The relations of TSS and most solute concentrations with stream discharge were stable through time, suggesting minimal long-term effects from repeated hurricane disturbance. Nitrate concentration, however, increased about threefold in response to hurricanes then returned to baseline over several years following a pseudo first-order decay pattern. The combined data sets provide insight about important hydrologic pathways, a long-term perspective to assess response to hurricanes, and a framework to evaluate future climate change in tropical ecosystems.

  9. Long-term patterns and short-term dynamics of stream solutes and suspended sediment in a rapidly weathering tropical watershed

    USGS Publications Warehouse

    Shanley, J.B.; McDowell, W.H.; Stallard, R.F.

    2011-01-01

    The 326 ha R??o Icacos watershed in the tropical wet forest of the Luquillo Mountains, northeastern Puerto Rico, is underlain by granodiorite bedrock with weathering rates among the highest in the world. We pooled stream chemistry and total suspended sediment (TSS) data sets from three discrete periods: 1983-1987, 1991-1997, and 2000-2008. During this period three major hurricanes crossed the site: Hugo in 1989, Hortense in 1996, and Georges in 1998. Stream chemistry reflects sea salt inputs (Na, Cl, and SO4), and high weathering rates of the granodiorite (Ca, Mg, Si, and alkalinity). During rainfall, stream composition shifts toward that of precipitation, diluting 90% or more in the largest storms, but maintains a biogeochemical watershed signal marked by elevated K and dissolved organic carbon (DOC) concentration. DOC exhibits an unusual "boomerang" pattern, initially increasing with flow but then decreasing at the highest flows as it becomes depleted and/or vigorous overland flow minimizes contact with watershed surfaces. TSS increased markedly with discharge (power function slope 1.54), reflecting the erosive power of large storms in a landslide-prone landscape. The relations of TSS and most solute concentrations with stream discharge were stable through time, suggesting minimal long-term effects from repeated hurricane disturbance. Nitrate concentration, however, increased about threefold in response to hurricanes then returned to baseline over several years following a pseudo first-order decay pattern. The combined data sets provide insight about important hydrologic pathways, a long-term perspective to assess response to hurricanes, and a framework to evaluate future climate change in tropical ecosystems. Copyright 2011 by the American Geophysical Union.

  10. Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer.

    PubMed

    Cheruvu, Praveena; Metcalfe, Su K; Metcalfe, Justin; Chen, Yuhchyau; Okunieff, Paul; Milano, Michael T

    2011-06-30

    Standard therapy for metastatic non small cell lung cancer (NSCLC) includes palliative systemic chemotherapy and/or radiotherapy. Recent studies of patients with limited metastases treated with curative-intent stereotactic body radiation therapy (SBRT) have shown encouraging survival. We hypothesized that patients treated with SBRT for limited metastases have comparable outcomes with those treated with curative-intent radiation for Stage III NSCLC. We retrospectively reviewed the records of NSCLC patients treated with curative-intent radiotherapy at the University of Rochester from 2000-2008. We identified 3 groups of patients with NSCLC: stage III, stage IV, and recurrent stage IV (initial stage I-II). All stage IV NSCLC patients treated with SBRT had ≤ 8 lesions. Of 146 patients, 88% had KPS ≥ 80%, 30% had > 5% weight loss, and 95% were smokers. The 5-year OS from date of NSCLC diagnosis for stage III, initial stage IV and recurrent stage IV was 7%, 14%, and 27% respectively. The 5-year OS from date of metastatic diagnosis was significantly (p < 0.00001) superior among those with limited metastases (≤ 8 lesions) versus stage III patients who developed extensive metastases not amenable to SBRT (14% vs. 0%). Stage IV NSCLC is a heterogeneous patient population, with a selected cohort apparently faring better than Stage III patients. Though patients with limited metastases are favorably selected by virtue of more indolent disease and/or less bulky disease burden, perhaps staging these patients differently is appropriate for prognostic and treatment characterization. Aggressive local therapy may be indicated in these patients, though prospective clinical studies are needed.

  11. Trajectories of mental health before and after old-age and disability retirement: a register-based study on purchases of psychotropic drugs.

    PubMed

    Laaksonen, Mikko; Metsä-Simola, Niina; Martikainen, Pekka; Pietiläinen, Olli; Rahkonen, Ossi; Gould, Raija; Partonen, Timo; Lahelma, Eero

    2012-09-01

    Retirement from paid work is a major life event facing increasingly large numbers of people in the coming years. We examined trajectories of mental health five years before and five years after old-age and disability retirement using data on purchases of psychotropic drugs. The study included all employees from the City of Helsinki, Finland, retiring between 2000-2008 due to old age (N=4456) or disability (N=2549). Purchases of psychotropic drugs were analyzed in 20 3-month intervals before and after retirement using graphical methods and growth curve models. Old-age retirement was unrelated to purchases of psychotropic drugs. Among disability retirees, psychotropic medication tripled before retirement. The average increase was 0.95 [95% confidence interval (95% CI) 0.73-1.16] daily defined doses (DDD) 5-1.5 years before retirement; from 1.5 years until retirement it was 5.68 DDD (95% CI 5.33-6.03) for each 3-month interval. After disability retirement, purchases of antidepressants decreased on average by 0.40 DDD (95% CI 0.57-0.23) for each 3-month interval, those of hypnotics and sedatives increased by 0.30 DDD (95% CI 0.12-0.47), and no changes were seen for other psychotropic drugs. The changes before and after retirement were largest among those who retired due to mental disorders and those whose retirement had been granted as temporary. While no overall decrease in psychotropic medication after retirement was observed, purchases of antidepressants decreased after disability retirement. Long-term trajectories suggest that disability retirement might be prevented if mental health problems were tackled more efficiently earlier in the pre-retirement period.

  12. Effect of defibrillation energy dose during in-hospital pediatric cardiac arrest.

    PubMed

    Meaney, Peter A; Nadkarni, Vinay M; Atkins, Dianne L; Berg, Marc D; Samson, Ricardo A; Hazinski, Mary Fran; Berg, Robert A

    2011-01-01

    To examine the effectiveness of initial defibrillation attempts. We hypothesized that (1) an initial shock dose of 2 ± 10 J/kg would be less effective for terminating fibrillation than suggested in published historical data and (2) a 4 J/kg shock dose would be more effective. This was a National Registry of Cardiopulmonary Resuscitation prospective, multisite, observational study of in-hospital pediatric (aged ≤18 years) ventricular fibrillation or pulseless ventricular tachycardia cardiac arrests from 2000-2008. Termination of ventricular fibrillation or pulseless ventricular tachycardia and event survival after initial shocks of 2 J/kg were compared with historic controls and a 4 J/kg shock dose. Of 266 children with 285 events, 173 of 285 (61%) survived the event and 61 of 266 (23%) survived to discharge. Termination of fibrillation after initial shock was achieved for 152 of 285 (53%) events. Termination of fibrillation with 2 ± 10 J/kg was much less frequent than that seen among historic control subjects (56% vs 91%; P < .001), but not different than 4 J/kg. Compared with 2 J/kg, an initial shock dose of 4 J/kg was associated with lower rates of return of spontaneous circulation (odds ratio: 0.41 [95% confidence interval: 0.21-0.81]) and event survival (odds ratio: 0.42 [95% confidence interval: 0.18-0.98]). The currently recommended 2 J/kg initial shock dose for in-hospital cardiac arrest was substantially less effective than previously published. A higher initial shock dose (4 J/kg) was not associated with superior termination of ventricular fibrillation or pulseless ventricular tachycardia or improved survival rates. The optimal pediatric defibrillation dose remains unknown.

  13. Seasonal streamflow forecasts in a semi-arid Andean watershed using remotely sensed snow cover data

    NASA Astrophysics Data System (ADS)

    Cartes, M.; McPhee, J.; Vargas, X.

    2009-04-01

    Forecasts of monthly streamflow during the snowmelt season are highly relevant for real-time decision making such as hydropower production scheduling, irrigation planning, and water transfers in market-driven water resource systems. The Chilean water bureau issues such forecasts, for a number of snowmelt-driven watersheds in northern and central Chile, based on measurements from a sparse network of snow course stations. This research aims at improving the accuracy of the government-issued seasonal forecasts by combining streamflow data and remotely sensed snow cover information through a recurrent neural network (RNN). The snow cover area (SCA) obtained from MODIS-Surface Reflectance product (MOD09) and the Normalized Differentiation Snow Index (NDSI), from 2000-2008 period, allow us to understand the variation of the snowmelt and accumulation processes in six different basins located in central Chile (32,5° - 34,5° south latitude; 69,5° -70,5° west longitude). For the three basins located at higher altitudes (> 1800 m.s.l.), after applying a cross-correlation procedure we determined a strong relation (r > 0.7) between SCA and the seasonal hydrograph, lagged around 4 months. The basin SCA, the NDSI at specific points inside the basin and past basin streamflow data are input to the RNN for recognizing the pattern variation of seasonal hydrograph through supervised learning. The determination coefficients for the validation period (r2 > 0.6) indicate a good support for the application of this methodology in normal-humid hydrological years. Particularly for the dryer years we obtain a considerable overestimation (around 30%) of the monthly snowmelt runoff. These results are limited by the availability of data for different types (dry, normal or humid) of hydrological years.

  14. Autobiographical episodic memory-based training for the treatment of mood, anxiety and stress-related disorders: A systematic review and meta-analysis.

    PubMed

    Hitchcock, Caitlin; Werner-Seidler, Aliza; Blackwell, Simon E; Dalgleish, Tim

    2017-03-01

    We review evidence for training programmes that manipulate autobiographical processing in order to treat mood, anxiety, and stress-related disorders, using the GRADE criteria to judge evidence quality. We also position the current status of this research within the UK Medical Research Council's (2000, 2008) framework for the development of novel interventions. A literature search according to PRISMA guidelines identified 15 studies that compared an autobiographical episodic memory-based training (AET) programme to a control condition, in samples with a clinician-derived diagnosis. Identified AET programmes included Memory Specificity Training (Raes, Williams, & Hermans, 2009), concreteness training (Watkins, Baeyens, & Read, 2009), Competitive Memory Training (Korrelboom, van der Weele, Gjaltema, & Hoogstraten, 2009), imagery-based training of future autobiographical episodes (Blackwell & Holmes, 2010), and life review/reminiscence therapy (Arean et al., 1993). Cohen's d was calculated for between-group differences in symptom change from pre- to post-intervention and to follow-up. We also completed meta-analyses for programmes evaluated across multiple studies, and for the overall effect of AET as a treatment approach. Results demonstrated promising evidence for AET in the treatment of depression (d=0.32), however effect sizes varied substantially (from -0.18 to 1.91) across the different training protocols. Currently, research on AET for the treatment of anxiety and stress-related disorders is not yet at a stage to draw firm conclusions regarding efficacy as there were only a very small number of studies which met inclusion criteria. AET offers a potential avenue through which low-intensity treatment for affective disturbance might be offered. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  15. Association of hospitalizations for asthma with seasonal and pandemic influenza.

    PubMed

    Gerke, Alicia K; Yang, Ming; Tang, Fan; Foster, Eric D; Cavanaugh, Joseph E; Polgreen, Philip M

    2014-01-01

    Although influenza has been associated with asthma exacerbations, it is not clear the extent to which this association affects health care use in the United States. The first goal of this project was to determine whether, and to what extent, the incidence of asthma hospitalizations is associated with seasonal variation in influenza. Second, we used influenza trends (2000-2008) to help predict asthma admissions during the 2009 H1N1 influenza pandemic. We identified all hospitalizations between 1998 and 2008 in the Nationwide Inpatient Sample from the Healthcare Cost and Utilization Project during which a primary diagnosis of asthma was recorded. Separately, we identified all hospitalizations during which a diagnosis of influenza was recorded. We performed time series regression analyses to investigate the association of monthly asthma admissions with influenza incidence. Finally, we applied these time series regression models using 1998-2008 data, to forecast monthly asthma admissions during the 2009 influenza pandemic. Based on time series regression models, a strong, significant association exists between concurrent influenza activity and incidence of asthma hospitalizations (P-value < 0.0001). Use of influenza data to predict asthma admissions during the 2009 H1N1 pandemic improved the mean squared prediction error by 60.2%. Influenza activity in the population is significantly associated with asthma hospitalizations in the United States, and this association can be exploited to more accurately forecast asthma admissions. Our results suggest that improvements in influenza surveillance, prevention and treatment may decrease hospitalizations of asthma patients. © 2013 The Authors. Respirology © 2013 Asian Pacific Society of Respirology.

  16. Population-based patterns of prescription androgen use, 1976-2008

    PubMed Central

    Hall, Susan A.; Ranganathan, Gayatri; Tinsley, Liane J.; Lund, Jennifer L.; Kupelian, Varant; Wittert, Gary A.; Kantoff, Philip W.; Morales, Alvaro; Araujo, Andre B.

    2014-01-01

    Purpose Prescription testosterone (T) has limited approved medical indications and is a controlled substance in Canada. Utilization studies in other Westernized countries have revealed sharp increases in T use in recent years. We examined medical use of androgens, including T, over a ≥30 year period among adult (18+) men in a population-based study set in a Canadian juridisdiction of universal health care. Methods Analyses were based on data from electronic records of dispensed prescriptions during 1976-2008 in Saskatchewan, Canada. All formulations of androgens listed in the provincial formulary (oral and injectable) were included. We examined demographics of users, androgen types used, switching patterns, and trends in the annual rate of use over time. Results There were 11,521 androgen users who were followed for an average of 11.8 years. Overall, 11 types of androgens were used and there were 86,812 dispensing events. The mean age at first use was 56.4 years (median: 58). Men had 7.5 prescription dispensing events on average (median: 2). The most commonly-used formulations were methyl-T (36.2% of users) followed by T-enanthate (32.5%), T-cypionate (22.3%) and T-undecanoate (20.0%). Most users (82%) did not switch among androgen types. The annual rate of use varied substantially over time, with a marked increase observed from 1994-1999 and a decrease from 2000-2008. Conclusions Androgen users were largely middle-aged and had relatively few dispensings. We hypothesize that observed secular trends in androgen use may align with drug treatment pattern changes for erectile dysfunction (ED), including the advent of phosphodiesterase type 5 inhibitors. PMID:24510484

  17. Relation of chelation regimes to cardiac mortality and morbidity in patients with thalassaemia major: an observational study from a large Greek Unit.

    PubMed

    Ladis, Vassilios; Chouliaras, Giorgos; Berdoukas, Vasilios; Moraitis, Panagiotis; Zannikos, Kirykos; Berdoussi, Eleni; Kattamis, Christos

    2010-10-01

    Cardiac complications because of transfusional iron overload are the main cause of death in thalassaemia major. New chelators and iron monitoring methods such as cardiac magnetic resonance (CMR) became available after the year 2000. We evaluated the impact of these new management options on cardiac mortality and morbidity. The risk of cardiac death during 1990-1999 and 2000-2008 was compared. Furthermore, after 1999, morbidity, mortality and reversal of heart failure were evaluated according to chelation regime: desferrioxamine (DFO), deferiprone (DFP) and combination therapy of DFO and DFP. We also present preliminary results for deferasirox (DFX), a new oral chelator. Three hundred and fifty-four patients were included in the de novo cardiac event evaluation, while 86 were included in the improvement component. The annual risk of cardiac death in patients aged between 20-30 and 30-40 reduced from 1.52% to 0.67% and 1.87% to 0.56%, respectively, before and after the year 2000. The risk for a de novo cardiac event for DFO was 9.1 times greater than that of DFP and 23.6 than with the combination of DFP and DFO. For DFX, there was one cardiac event over 269 patient-years. The risk of cardiac death was 9.5 per 1000 patient-years for DFO, 2.5 on DFP, 1.4 on combination. In the DFX group no cardiac deaths were recorded. The odds of improvement were 8.5 times greater with DFP and 6.1 with combination therapy compared to DFO. The new chelation regimes, together with CMR have contributed significantly to the reduction in cardiac morbidity and mortality in patients with thalassaemia major. © 2010 John Wiley & Sons A/S.

  18. Is the prescribing behavior of Chinese physicians driven by financial incentives?

    PubMed

    Chen, Chun; Dong, Weizhen; Shen, Jay J; Cochran, Christopher; Wang, Ying; Hao, Mo

    2014-11-01

    The prescribing behavior to prescribe high-priced drugs has been hypothesized to be related to the increasing drug expenditures in China, but little empirical evidence exists. The purpose of this study was to examine whether Chinese physicians, driven by financial incentives, tend to prescribe high-priced drugs. The 2000-2008 drug data in the Yangtze River Basin Hospitals' Drug Use Analysis System were analyzed to examine the prescription patterns of penicillins and cephalosporins in Shanghai. Among the top-100 drugs (by volume), cephalosporins cost as 1.1- 2.3 times as penicillins and their volume was 1.7-18.2 times. Revenues generated from prescribing cephalosporins were 3.4-24.2 times as those from prescribing penicillins. The tendency of prescribing relatively high-priced drugs was observed given the same chemical name, dosage, and specification but different trade names. Furthermore, high-priced drugs remained on the top-100 list with increasing volumes, while some lower-priced drugs exited from the list due to decreases in volumes. Facing the policy dilemmas, the Chinese government needs to implement a new financially rewarding system in which hospitals and physicians are able to achieve financial gains in a cost-effective way including prescribing similar drugs with lower prices. Reforming hospitals' payment methods is necessary and feasible to reshape financial incentives of healthcare providers. The combination of the global budget policy and financial incentive measures would be likely to change providers' prescribing behaviors towards a cost-effective direction. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. A new emission inventory for nonagricultural open fires in Asia from 2000 to 2009

    NASA Astrophysics Data System (ADS)

    Song, Yu; Chang, Di; Liu, Bing; Miao, Weijie; Zhu, Lei; Zhang, Yuanhang

    2010-01-01

    Open fires play a significant role in atmospheric pollution and climatic change. This work aims to develop an emission inventory for nonagricultural open fires in Asia using the newly released MODIS (Moderate Resolution Imaging Spectroradiometer) burned area product (MCD45A1), as the MODIS sensor cannot efficiently detect field crop residue burning. Country-level or province-specific biomass density data were used as fuel loads. Moisture contents were taken into account when calculating combustion factors for grass fuel. During the nine fire years 2000-2008, both burned areas and fire emissions clearly presented spatial and seasonal variations. Extensive nonagricultural open fires were concentrated in the months of February and March, while another peak was between August and October. Indonesia was the most important contributor to fire emission, which was largely attributable to peat burning. Myanmar, India, and Cambodia together contributed approximately half of the total burned area and emission. The annual emissions for CO2, CO, CH4, NMHCs, NOx, NH3, SO2, BC, OC, PM2.5, and PM10 were 83 (69-103), 6.1 (4.6-8.2), 0.38 (0.24-0.57), 0.64 (0.36-1.0), 0.085 (0.074-0.10), 0.31 (0.17-0.48), 0.030 (0.024-0.037), 0.023 (0.020-0.028), 0.27 (0.22-0.33), 2.0 (1.6-2.6), and 2.2 (1.7-2.9) Tg yr - 1, respectively. This inventory has a daily temporal resolution and 500 m spatial resolution, and covers a long period, from April 2000 to February 2009. It could be used in global and regional air quality modeling.

  20. Interpreting food processing through dietary mechanical properties: a Lemur catta case study.

    PubMed

    Yamashita, Nayuta; Cuozzo, Frank P; Sauther, Michelle L

    2012-06-01

    Knowledge of dietary mechanical properties can be informative about physical consequences to consumers during ingestion and mastication. In this article, we examine how Tamarindus indica fruits can affect dental morphology in a population of ring-tailed lemurs (Lemur catta) at Beza Mahafaly special reserve in southwestern Madagascar. Ring-tailed lemurs in tamarind dominated gallery forests exhibit extreme wear and tooth loss on their postcanine dentition that has been related to processing T. indica fruits. We measured and compared mechanical properties of individual food parts in the diet of ring-tailed lemurs in different seasons in 1999-2000, 2008, and 2010. Fracture toughness, hardness, and modulus of foods were measured with a portable mechanical tester. The ripe fruits of T. indica are indeed the toughest and hardest foods ingested by the lemurs. In addition, they are among the largest foods consumed, require high numbers of ingestive bites to process, and are the most frequently eaten by volume. During controlled cutting tests of the ripe fruit shell, multiple runaway side cracks form alongside the cut. Similarly, the lemurs repeatedly bite the ripe shell during feeding and thereby introduce multiple cracks that eventually fragment the shell. Studies of enamel microstructure (e.g., Lucas et al.: BioEssays 30 (2008) 374-385; Campbell et al., 2011) advance the idea that the thin enamel of ring-tailed lemur teeth is susceptible to substantial micro-cracking that rapidly erodes the teeth. We conclude that micro-cracking from repeated loads, in combination with the mechanical and physical properties of the fruit, is primarily responsible for the observed dental damage.

  1. Population attributable risks of patient, child and organizational risk factors for perinatal mortality in hospital births.

    PubMed

    Poeran, Jashvant; Borsboom, Gerard J J M; de Graaf, Johanna P; Birnie, Erwin; Steegers, Eric A P; Bonsel, Gouke J

    2015-04-01

    The main objective of this study was to estimate the contributing role of maternal, child, and organizational risk factors in perinatal mortality by calculating their population attributable risks (PAR). The primary dataset comprised 1,020,749 singleton hospital births from ≥22 weeks' gestation (The Netherlands Perinatal Registry 2000-2008). PARs for single and grouped risk factors were estimated in four stages: (1) creating a duplicate dataset for each PAR analysis in which risk factors of interest were set to the most favorable value (e.g., all women assigned 'Western' for PAR calculation of ethnicity); (2) in the primary dataset an elaborate multilevel logistic regression model was fitted from which (3) the obtained coefficients were used to predict perinatal mortality in each duplicate dataset; (4) PARs were then estimated as the proportional change of predicted- compared to observed perinatal mortality. Additionally, PARs for grouped risk factors were estimated by using sequential values in two orders: after PAR estimation of grouped maternal risk factors, the resulting PARs for grouped child, and grouped organizational factors were estimated, and vice versa. The combined PAR of maternal, child and organizational factors is 94.4 %, i.e., when all factors are set to the most favorable value perinatal mortality is expected to be reduced with 94.4 %. Depending on the order of analysis, the PAR of maternal risk factors varies from 1.4 to 13.1 %, and for child- and organizational factors 58.7-74.0 and 7.3-34.3 %, respectively. In conclusion, the PAR of maternal-, child- and organizational factors combined is 94.4 %. Optimization of organizational factors may achieve a 34.3 % decrease in perinatal mortality.

  2. Differences in the consumption rates and regulatory barriers to the accessibility of strong opioid analgesics in Israel and St. Petersburg.

    PubMed

    Ponizovsky, Alexander M; Pchelintsev, Michael V; Marom, Eli; Zvartau, Edwin E

    2012-01-01

    To compare trends in opioid consumption in Israel and St. Petersburg/Russia (morphine, oxycodone, pethidine, fentanyl, methadone, buprenorphine, trimeperidine, and papaveretum) over the period 2000-2008, and to describe the regulatory barriers to their accessibility as an exploratory variable for between-country differences. Data were drawn from the databases maintained by the Israel Ministry of Health's Pharmaceutical Administration and the St. Petersburg Central Pharmaceutical Reserve. The data were converted into a defined daily dose (DDD)/1,000 inhabitants/day. Regulation was evaluated according to the WHO guidelines for the assessment of national opioid regulation. The opioid consumption rates in Israel were substantially higher than those in St. Petersburg. The excess in DDD/1,000 inhabitants/day was for fentanyl +0.287 in 2000 and +1.206 in 2008, for morphine +0.245 in 2000 and +0.122 in 2008, and for pethidine/trimeperidine +0.035 in 2000 and +0.007 in 2008. Oxycodone consumption increased in Israel from 0.31 DDD/1,000 inhabitants/day in 2000 to 0.46 DDD/1,000 inhabitants/day in 2008, whereas this analgesic is not available in St. Petersburg. Methadone and buprenorphine consumption rose in Israel, whereas these drugs are not available in Russia. Conversely, omnopon consumption decreased in St. Petersburg from 0.0206 DDD/1,000 inhabitants/day in 2000 to 0.00304 DDD/1,000 inhabitants/day in 2008, whereas the compound is not available in Israel. St. Petersburg differs from Israel with less opioid formulary availability and greater regulatory restrictions. The results suggest that strong opioid analgesics consumption rates in St. Petersburg yield those in Israel, and that the between-countries differences in opioid formularies availability and legal and regulatory barriers to opioids accessibility are responsible for the consumption discrepancies.

  3. Patient Tobacco Use, Quit Attempts, and Perceptions of Healthcare Provider Practices in a Safety-Net Healthcare System

    PubMed Central

    Moody-Thomas, Sarah; Celestin, Michael D.; Tseng, Tung-Sung; Horswell, Ronald

    2013-01-01

    Background Although smoking rates in the United States (US) are high, healthcare systems and clinicians can increase cessation rates through application of the US Public Health Service tobacco treatment guideline (2000, 2008). In primary care settings, however, guideline implementation remains low. This report presents the results from an assessment of patient tobacco use, quit attempts, and perceptions of provider treatment before (2004) and after (2010) guideline implementation. Methods By use of a systems approach, the Louisiana Tobacco Control Initiative integrated evidence-based treatment of tobacco use into patient care practices in Louisiana's public hospital system. This prospective study, designed to collect data at 2 time points for the purpose of evaluating the effect of the 5A protocol (ask, advise, assess, assist, and arrange), included 571 and 889 adult patients selected from primary care clinics in 2004 and 2010, respectively. Chi-square analyses determined differences between survey administrations, along with direct standardization of weighted rates to control for confounding factors. Results Patient reports indicated that provider adherence to the 5A clinical protocol increased from 2004 to 2010. Significant (P<0.001) improvements were observed for the assess (39% vs 72%), assist (24% vs 76%), and arrange (8% vs 31%) treatment variables. Patient-reported quit attempts increased, along with awareness of cessation services (from 19% to 70%, P<0.001), while use of cessation medications decreased (from 23% to 5%, P<0.002). Conclusion Following implementation of the guideline, significant improvements were noted in patient reports of provider treatment and awareness of cessation services. PMID:24052766

  4. Assessment of primary and secondary ambient particle trends using satellite aerosol optical depth and ground speciation data in the New England region, United States.

    PubMed

    Lee, Hyung Joo; Kang, Choong-Min; Coull, Brent A; Bell, Michelle L; Koutrakis, Petros

    2014-08-01

    The effectiveness of air pollution emission control policies can be evaluated by examining ambient pollutant concentration trends that are observed at a large number of ground monitoring sites over time. In this paper, we used ground monitoring measurements in conjunction with satellite aerosol optical depth (AOD) data to investigate fine particulate matter (PM2.5; particulate matter with aerodynamic diameter ≤ 2.5 µm) trends and their spatial patterns over a large U.S. region, New England, during 2000-2008. We examined the trends in rural and urban areas to get a better insight about the trends of regional and local source emissions. Decreases in PM2.5 concentrations (µg/m(3)) were more pronounced in urban areas than in rural ones. In addition, the highest and lowest PM2.5 decreases (µg/m(3)) were observed for winter and summer, respectively. Together, these findings suggest that primary particle concentrations decreased more relative to secondary ones. This is also supported by the analysis of the speciation data which showed that downward trends of primary pollutants including black carbon were stronger than those of secondary pollutants including sulfate. Furthermore, this study found that ambient primary pollutants decreased at the same rate as their respective source emissions. This was not the case for secondary pollutants which decreased at a slower rate than that of their precursor emissions. This indicates that concentrations of secondary pollutants depend not only on the primary emissions but also on the availability of atmospheric oxidants which might not change during the study period. This novel approach of investigating spatially varying concentration trends, in combination with ground PM2.5 species trends, can be of substantial regulatory importance.

  5. Older statin initiators in Finland - cardiovascular risk profiles and persistence of use.

    PubMed

    Upmeier, Eveliina; Korhonen, Maarit Jaana; Rikala, Maria; Helin-Salmivaara, Arja; Huupponen, Risto

    2014-06-01

    The benefits of statin treatment initiated in advanced age are largely unknown; however, good adherence to treatment is essential for beneficial effects to be achieved also when treating older people. This study characterizes older statin initiators, including their cardiovascular risk profiles and morbidity, and investigates patterns of treatment persistence. Longitudinal register-based study. All statin initiators in Finland aged ≥70 in 2000-2008 (n = 157,709) were identified from the nationwide Prescription Register. Using information from comprehensive health registers, the initiators were classified as having low, moderate, or high cardiovascular risk. For the initiators in 2000 and 2004, patterns of persistence were evaluated over a 4-year follow-up using the anniversary method. The annual number of statin initiators increased from 15,082 to 19,728; the proportion of those aged ≥80 increased from 12.9 to 25.8 %. The prevalence of coronary heart disease at statin initiation decreased from 45.5 to 28.1 %. Only every tenth initiator (9.2-11.7 %) was estimated to have low cardiovascular risk each year. Four in five initiators (76.9-80.5 %) persisted with statin treatment after 1 year. The probability to survive and remain persistent for 4 years was 51.6 % and the probability to discontinue within the first year without restarting in the subsequent 3 years was 9.1 %. There were no noticeable differences in persistence across the risk groups. Long-term persistence with statins among older people was good across cardiovascular risk groups. These findings are consistent with the notion that the decision on long-term continuation of statin use is made during the first year of treatment.

  6. Pneumoconiosis among underground bituminous coal miners in the United States: is silicosis becoming more frequent?

    PubMed

    Laney, A Scott; Petsonk, Edward L; Attfield, Michael D

    2010-10-01

    Epidemiological reports since 2000 have documented increased prevalence and rapid progression of pneumoconiosis among underground coal miners in the United States. To investigate a possible role of silica exposure in the increase, we examined chest x-rays (CXRs) for specific abnormalities (r-type small opacities) known to be associated with silicosis lung pathology. Underground coal miners are offered CXRs every 5 years. Abnormalities consistent with pneumoconiosis are recorded by National Institute for Occupational Safety and Health (NIOSH) B Readers using the International Labour Organization Classification of Radiographs of Pneumoconioses. CXRs from 1980 to 2008 of 90 973 participating miners were studied, focussing on reporting of r-type opacities (small rounded opacities 3-10 mm in diameter). Log binomial regression was used to calculate prevalence ratios adjusted for miner age and profusion category. Among miners from Kentucky, Virginia and West Virginia, the proportion of radiographs showing r-type opacities increased during the 1990s (prevalence ratio (PR) 2.5; 95% CI 1.7 to 3.7) and after 1999 (PR 4.1; 95% CI 3.0 to 5.6), compared to the 1980s (adjusted for profusion category and miner age). The prevalence of progressive massive fibrosis in 2000-2008 was also elevated compared to the 1980s (PR 4.4; 95% CI 3.1 to 6.3) and 1990s (PR 3.8; 95% CI 2.1 to 6.8) in miners from Kentucky, Virginia and West Virginia. The increasing prevalence of pneumoconiosis over the past decade and the change in the epidemiology and disease profile documented in this and other recent studies imply that US coal miners are being exposed to excessive amounts of respirable crystalline silica.

  7. Improving the diagnostic criteria for primary liver graft non-function in adults utilizing standard and transportable laboratory parameters. An outcome based analysis.

    PubMed

    Al-Freah, Mohammad A B; McPhail, Mark J W; Dionigi, Elena; Foxton, Matthew R; Auzinger, Georg; Rela, Mohamed; Wendon, Julia A; O'Grady, John G; Heneghan, Michael A; Heaton, Nigel D; Bernal, William

    2017-02-15

    Current diagnostic criteria for primary non-function (PNF) of liver grafts are based on clinical experience rather than statistical methods. A retrospective, single centre study was conducted of all adults (n=1,286) who underwent primary liver transplant 2000-2008 in our centre. Laboratory variable during the first post-liver transplant week were analysed. Forty two patients (3.7%) had 2-week graft failure. Transplant albumin, day-1 AST, day-1 lactate, day-3 bilirubin, day-3 INR and day-7 AST were independently associated with PNF on multivariate logistic regression. PNF score =(0.000280*D1AST)+(0.361*D1 Lactate)+(0.00884*D3 Bilirubin)+(0.940*D 3 INR)+(0.00153*D7 AST)-(0.0972*TxAlbumin)-4.5503. ROC analysis showed the model AUROC of 0.912 (0.889 -0.932) was superior to the current United Kingdom (UK) PNF criteria of 0.669 (0.634-0.704, p<0.0001). When applied to a validation cohort (n=386, 34.4% patients) the model had AUROC of 0.831 (0.789 -0.867) compared to the UK EGD criteria of 0.674 (0.624-0.721). The new model performed well after exclusion of patients with marginal grafts and when modified to include variables from the first three post-LT days only (AUROC of 0.818, 0.776-0.856, p=0.001). This model is superior to the current UK PNF criteria and is based on statistical methods. The model is also applicable to recipients of all types of grafts (marginal and non-marginal). This article is protected by copyright. All rights reserved.

  8. A Statistical Method to Estimate PM2.5 Concentrations over Europe from Meteorology and Its Application to the Effect of Climate Change

    NASA Astrophysics Data System (ADS)

    Lecoeur, Ève; Seigneur, Christian; Pagé, Christian; Terray, Laurent

    2013-04-01

    Atmospheric particulate matter (PM) pollution has become a field of great interest because of its impacts on human health, climate change, and atmospheric visibility. In particular, fine particles with an aerodynamical diameter less than or equal to 2.5 μm (PM2.5) are regulated in North America and Europe. It is well-known that PM concentrations depend on meteorology via its effects on the emissions, the kinetics of chemical reactions, the gas/particle partitionning, and the removal of PM from the atmosphere. Therefore, climate change is expected to affect PM concentrations. First studies of the effect of climate change on air quality have originally been conducted on ozone, whereas the study of its effect on PM concentrations is more recent. However, most of the work pertaining PM has focused so far on the United States. Furthermore, there is currently no strong consensus on the effects of the present and future climate on PM2.5 concentrations. Therefore, we propose here a statistical method which estimates PM2.5 concentrations over Europe from the meteorology and which can be applied to present and future climates. In more detail, we apply a multiple linear regression model to understand the relationships between PM2.5 concentrations and meteorological variables in Europe. Multiple linear regression predictors include temperature, precipitation, wind speed, and weather types, which are representative of the large-scale atmospheric circulation. We use the results of a 9-year (2000-2008) model simulation as PM2.5 pseudo-observations. By assuming that the weather types will remain the same in the future (stationarity), we use different model predictions provided by the IPCC to study how the frequency of the weather types will change in the future. The statistical model is used to estimate future PM2.5 concentrations that would result from this climate change.

  9. Verification of Atmospheric Signals Associated with Major Seismicity by Space and Terrestrial Observations

    NASA Technical Reports Server (NTRS)

    Taylor, Patrick

    2008-01-01

    Observations from the last twenty years suggest the existence of electromagnetic (EM) phenomena during or preceding some earthquakes [Haykawa et a!, 2004; Pulinets at al, 1999,2004, 2006, Ouzounov et all 2007 and Liu et all 20041. Both our previous studies [Pulinets at al, 2005, 2006, Ouzounov et al, 2006, 20071 and the latest review by the Earthquake Remote Precursor Sensing panel [ERPS; 2003- 20051; have shown that there were precursory atmospheric TIR signals observed on the ground and in space associated with several recent earthquakes. [Tramutoli at al, 2005, 2006, Cervone et al, 2006, Ouzounov et all 2004,2006JT.o study these signals, we applied both multi parameter statistical analysis and data mining methods that require systematic measurements from an Integrated Sensor Web of observations of several physical and environmental parameters. These include long wave earth infra-red radiation, ionospheric electrical and magnetic parameters, temperature and humidity of the boundary layer, seismicity and may be associated with major earthquakes. Our goal is to verify the earthquake atmospheric correlation in two cases: (i) backward analysis - 2000-2008 hindcast monitoring of multi atmospheric parameters over the Kamchatka region, Russia ; and (ii) forward real-time alert analysis over different seismo-tectonic regions for California, Turkey, Taiwan and Japan. Our latest results, from several post-earthquake independent analyses of more then 100 major earthquakes, show that joint satellite and some ground measurements, using an integrated web, could provide a capability for observing pre-earthquake atmospheric signals by combining the information from multiple sensors into a common framework. Using our methodology, we evaluated and compared the observed signals preceding the latest M7.9 Sichuan earthquake (0511212008), M8.0 earthquake in Peru (0811512007), M7.6 Kashmir earthquake (1010812005) and M9.0 Sumatra earthquake (1212812004). We found evidence of the

  10. Factors associated with the risk of West Nile virus among crows in New York State.

    PubMed

    DeCarlo, C H; Clark, A B; McGowan, K J; Ziegler, P E; Glaser, A L; Szonyi, B; Mohammed, H O

    2011-06-01

    West Nile virus (WNV) is transmitted between avian hosts in enzootic cycles by a mosquito vector. The virus has significant disease effects on humans and equines when it bridges into an epizootic cycle. As the initial epidemic of WNV in 1999, perennial outbreaks in New York State suggest the local establishment of natural foci with perpetuation of the virus among susceptible hosts rather than reintroduction of the virus. The factors that play a role in the perpetuation of the virus are not fully understood. American crows (Corvus brachyrhynchos) are known to be highly susceptible to infection with the virus. We investigate the factors that put crows at risk of infection in Tompkins County, New York during the period of 2000-2008 in a case-control study. Cases were crow carcasses that were found dead and tested positive for WNV using real time reverse transcription or VecTest. Data on putative risk factors were collected and assessed for significance of association with the presence of WNV using logistic regression analysis to evaluate the significance of each factor while simultaneously controlling for the effect of others. The risk of a crow carcass testing WNV positive varied with age, season of the year and ecological area where the carcass was found. Crows that were more than 1-year-old were four times more likely to be WNV positive in comparison to birds that were less than 1 year of age. It was three times more likely to find WNV positive carcasses in residential areas in comparison to rural areas. The risk of testing WNV positive did not vary by sex of the crow carcasses. © 2010 Blackwell Verlag GmbH.

  11. Increased use of lethal methods and annual increase of suicide rates in Korean adolescents: comparison with adolescents in the United States.

    PubMed

    Park, Subin; Cho, Soo-Churl; Kim, Bung-Nyun; Kim, Jae-Won; Yoo, Hee Jeong; Hong, Jin Pyo

    2014-03-01

    The lethality of the suicide method is a strong risk factor for completed suicide. We examined whether the annual change in the pattern of suicide methods was related to the annual change in suicide rates among adolescents in South Korea and the United States. We analyzed annual data for the 2000-2009 period for South Korea and the 2000-2008 period for the United States to examine time trends in the suicide rates and suicide methods of adolescents aged 10-19 years in two countries. Data on suicide methods were obtained from the World Health Organization (WHO) mortality database. Suicide rates among adolescents in the United States have remained relatively steady since 2000, whereas the suicide among Korean adolescents has increased. Between 2000 and 2009, the most common suicide method among Korean adolescents was jumping for boys and girls, whereas it was hanging for girls and firearms for boys in the United States. Along with the annual increase in suicide rates in South Korea, the incidences of jumping among males and hanging (and recently jumping) among females have increased steadily, whereas suicide by self-poisoning steadily decreased. In the United States, between 2000 and 2008, the proportion of suicides committed by hanging increased, whereas those committed using firearms steadily decreased, particularly among adolescent females. These findings suggest that the increased use of lethal suicide methods is reflected in the increase in suicide rates in Korean adolescents. The most fruitful approach to addressing the rises in jumping suicides among Korean adolescents and hanging suicides among adolescents in the United States may be through population-based initiatives to reduce the physical availability (e.g., limiting access to or fencing off tall structures) and the social acceptability (e.g., effective and responsible regulations for reporting suicide) of these methods. © 2013 The Authors. Journal of Child Psychology and Psychiatry © 2013 Association

  12. Food safety hazards associated with consumption of raw milk.

    PubMed

    Oliver, Stephen P; Boor, Kathryn J; Murphy, Steven C; Murinda, Shelton E

    2009-09-01

    An increasing number of people are consuming raw unpasteurized milk. Enhanced nutritional qualities, taste, and health benefits have all been advocated as reasons for increased interest in raw milk consumption. However, science-based data to substantiate these claims are limited. People continue to consume raw milk even though numerous epidemiological studies have shown clearly that raw milk can be contaminated by a variety of pathogens, some of which are associated with human illness and disease. Several documented milkborne disease outbreaks occurred from 2000-2008 and were traced back to consumption of raw unpasteurized milk. Numerous people were found to have infections, some were hospitalized, and a few died. In the majority of these outbreaks, the organism associated with the milkborne outbreak was isolated from the implicated product(s) or from subsequent products made at the suspected dairy or source. In contrast, fewer milkborne disease outbreaks were associated with consumption of pasteurized milk during this same time period. Twenty nine states allow the sale of raw milk by some means. Direct purchase, cow-share or leasing programs, and the sale of raw milk as pet food have been used as means for consumers to obtain raw milk. Where raw milk is offered for sale, strategies to reduce risks associated with raw milk and products made from raw milk are needed. Developing uniform regulations including microbial standards for raw milk to be sold for human consumption, labeling of raw milk, improving sanitation during milking, and enhancing and targeting educational efforts are potential approaches to this issue. Development of pre- and postharvest control measures to effectively reduce contamination is critical to the control of pathogens in raw milk. One sure way to prevent raw milk-associated foodborne illness is for consumers to refrain from drinking raw milk and from consuming dairy products manufactured using raw milk.

  13. The Association of Ethnic Minority Density with Late Entry into Antenatal Care in the Netherlands

    PubMed Central

    Posthumus, Anke G.; Schölmerich, Vera L. N.; Steegers, Eric A. P.; Kawachi, Ichiro; Denktaş, Semiha

    2015-01-01

    In the Netherlands, non-Western ethnic minority women make their first antenatal visit later than native Dutch women. Timely entry into antenatal care is important as it provides the opportunity for prenatal screening and the detection of risk factors for adverse pregnancy outcomes. In this study we explored whether women's timely entry is influenced by their neighborhood. Moreover, we assessed whether ethnic minority density (the proportion of ethnic minorities in a neighborhood) influences Western and non-Western ethnic minority women's chances of timely entry into care differently. We hypothesized that ethnic minority density has a protective effect against non-Western women's late entry into care. Data on time of entry into care and other individual-level characteristics were obtained from the Netherlands Perinatal Registry (2000-2008; 97% of all pregnancies). We derived neighborhood-level data from three other national databases. We included 1,137,741 pregnancies of women who started care under supervision of a community midwife in 3422 neighborhoods. Multi-level logistic regression was used to assess the associations of individual and neighborhood-level determinants with entry into antenatal care before and after 14 weeks of gestation. We found that neighborhood characteristics influence timely entry above and beyond individual characteristics. Ethnic minority density was associated with a higher risk of late entry into antenatal care. However, our analysis showed that for non-Western women, living in high ethnic minority density areas is less detrimental to their risk of late entry than for Western women. This means that a higher proportion of ethnic minority residents has a protective effect on non-Western women's chances of timely entry into care. Our results suggest that strategies to improve timely entry into care could seek to create change at the neighborhood level in order to target individuals likely of entering care too late. PMID:25856150

  14. Improving Hospital Reporting of Patient Race and Ethnicity--Approaches to Data Auditing.

    PubMed

    Zingmond, David S; Parikh, Punam; Louie, Rachel; Lichtensztajn, Daphne Y; Ponce, Ninez; Hasnain-Wynia, Romana; Gomez, Scarlett Lin

    2015-08-01

    To investigate new metrics to improve the reporting of patient race and ethnicity (R/E) by hospitals. California Patient Discharge Database (PDD) and birth registry, 2008-2009, Healthcare and Cost Utilization Project's State Inpatient Database, 2008-2011, cancer registry 2000-2008, and 2010 US Census Summary File 2. We examined agreement between hospital reported R/E versus self-report among mothers delivering babies and a cancer cohort in California. Metrics were created to measure root mean squared differences (RMSD) by hospital between reported R/E distribution and R/E estimates using R/E distribution within each patient's zip code of residence. RMSD comparisons were made to corresponding "gold standard" facility-level measures within the maternal cohort for California and six comparison states. Maternal birth hospitalization (linked to the state birth registry) and cancer cohort records linked to preceding and subsequent hospitalizations. Hospital discharges were linked to the corresponding Census zip code tabulation area using patient zip code. Overall agreement between the PDD and the gold standard for the maternal cohort was 86 percent for the combined R/E measure and 71 percent for race alone. The RMSD measure is modestly correlated with the summary level gold standard measure for R/E (r = 0.44). The RMSD metric revealed general improvement in data agreement and completeness across states. "Other" and "unknown" categories were inconsistently applied within inpatient databases. Comparison between reported R/E and R/E estimates using zip code level data may be a reasonable first approach to evaluate and track hospital R/E reporting. Further work should focus on using more granular geocoded data for estimates and tracking data to improve hospital collection of R/E data. © Health Research and Educational Trust.

  15. Does exclusion of cancers registered only from death-certificate information diminish socio-demographic disparities in recorded survival?

    PubMed

    Tervonen, Hanna E; Roder, David; Morrell, Stephen; You, Hui; Currow, David C

    2017-06-01

    Death Certificate Only (DCO) cancer cases are commonly excluded from survival analyses due to unknown survival time. This study examines whether socio-demographic factors are associated with DCO diagnosis, and the potential effects of excluding DCO cases on socio-demographic cancer survival disparities in NSW, Australia. NSW Cancer Registry data for cases diagnosed in 2000-2008 were used in this study. Logistic regression was used to estimate the odds of DCO registration by socio-demographic sub-group (socio-economic disadvantage, residential remoteness, country of birth, age at diagnosis). Cox proportional hazard regression was used to estimate the probability of death from cancer by socio-demographic subgroup when DCO cases were included and excluded from analyses. DCO cases consisted of 1.5% (n=4336) of all cases (n=299,651). DCO diagnosis was associated with living in socio-economically disadvantaged areas (most disadvantaged compared with least disadvantaged quintile: odds ratio OR 1.25, 95%CI 1.12-1.40), living in inner regional (OR 1.16, 95%CI 1.08-1.25) or remote areas (OR 1.48, 95%CI 1.01-2.19), having an unknown country of birth (OR 1.63, 95%CI 1.47-1.81) and older age. Including or excluding DCO cases had no significant impact on hazard ratios for cancer death by socio-economic disadvantage quintile or remoteness category, and only a minor impact on hazard ratios by age. Socio-demographic factors were associated with DCO diagnosis in NSW. However, socio-demographic cancer survival disparities remained unchanged or varied only slightly irrespective of including/excluding DCO cases. Further research could examine the upper limits of DCO proportions that significantly alter estimated cancer survival differentials if DCOs are excluded. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  16. A Geospatial Approach to Mapping Bioenergy Potential of Perennial Crops in North American Tallgrass Prairie

    NASA Astrophysics Data System (ADS)

    Wang, S.; Fritschi, F. B.; Stacy, G.

    2009-12-01

    Biomass is the largest source of renewable energy in the United States and is expected to replace 30% of the domestic petroleum consumption by 2030. Corn ethanol currently constitutes 99% of the country’s biofuels. Extended annual crop planting for biofuel production, however, has raised concerns about long-term environmental, ecological and socio-economical consequences. More sustainable bioenergy resources might therefore be developed to meet the energy demand, food security and climate policy. The DOD has identified switchgrass (Panicum virgatum L.) as a model bioenergy crop. Switchgrass, along with other warm-season grasses, is native to the pre-colonial tallgrass prairie in North America. This study maps the spatial distributions of prairie grasses and marginal croplands in the tallgrass prairie with remote sensing and GIS techniques. In 2000-2008, the 8-day composition MODIS imagery was downloaded to calculate the normalized difference vegetation index (NDVI). With pixel-level temporal trajectory of NDVI, time-series trend analysis was performed to identify native prairie grasses based on their phenological uniqueness. In a case study in southwest Missouri, this trajectory approach distinguished more than 80% of warm-season prairie grasslands from row crops and cool-season pastures (Figure 1). Warm season grasses dominated in the 19 public prairies in the study area in a range of 45-98%. This study explores the geographic context of current and potential perennial bioenergy supplies in the tallgrass prairie. Beyond the current findings, it holds promise for further investigations to provide quantitative economic and environmental information in assisting bioenergy policy decision-making. Figure 1 The distribution of grasslands in the study area. The "WSG", "CSG" and “non-grass” represent warm-season prairie grasses, introduced cool-season grasses and crops and other non-grasses.

  17. Exposure to trihalomethanes through different water uses and birth weight, small for gestational age, and preterm delivery in Spain.

    PubMed

    Villanueva, Cristina M; Gracia-Lavedán, Esther; Ibarluzea, Jesús; Santa Marina, Loreto; Ballester, Ferran; Llop, Sabrina; Tardón, Adonina; Fernández, Mariana F; Freire, Carmen; Goñi, Fernando; Basagaña, Xavier; Kogevinas, Manolis; Grimalt, Joan O; Sunyer, Jordi

    2011-12-01

    Evidence associating exposure to water disinfection by-products with reduced birth weight and altered duration of gestation remains inconclusive. We assessed exposure to trihalomethanes (THMs) during pregnancy through different water uses and evaluated the association with birth weight, small for gestational age (SGA), low birth weight (LBW), and preterm delivery. Mother-child cohorts set up in five Spanish areas during the years 2000-2008 contributed data on water ingestion, showering, bathing, and swimming in pools. We ascertained residential THM levels during pregnancy periods through ad hoc sampling campaigns (828 measurements) and regulatory data (264 measurements), which were modeled and combined with personal water use and uptake factors to estimate personal uptake. We defined outcomes following standard definitions and included 2,158 newborns in the analysis. Median residential THM ranged from 5.9 μg/L (Valencia) to 114.7 μg/L (Sabadell), and speciation differed across areas. We estimated that 89% of residential chloroform and 96% of brominated THM uptakes were from showering/bathing. The estimated change of birth weight for a 10% increase in residential uptake was -0.45 g (95% confidence interval: -1.36, 0.45 g) for chloroform and 0.16 g (-1.38, 1.70 g) for brominated THMs. Overall, THMs were not associated with SGA, LBW, or preterm delivery. Despite the high THM levels in some areas and the extensive exposure assessment, results suggest that residential THM exposure during pregnancy driven by inhalation and dermal contact routes is not associated with birth weight, SGA, LBW, or preterm delivery in Spain.

  18. Three-dimensional properties of mesoscale eddies in the South China Sea based on eddy-resolving model output

    NASA Astrophysics Data System (ADS)

    Lin, Xiayan; Dong, Changming; Chen, Dake; Liu, Yu; Yang, Jingsong; Zou, Bin; Guan, Yuping

    2015-05-01

    Last decade has witnessed extensive studies on mesoscale oceanic eddies in the Southern China Sea (SCS), however most of these studies are focused on the surface eddies, and three-dimensional features of eddies are not well known except some individual eddies. We apply a three-dimensional eddy detection scheme to a 9-year (2000-2008) eddy-resolving numerical solution to acquire three-dimensional eddy data set in the SCS. The model solution is validated with observational data in terms of both seasonal and intra-seasonal scales. The statistical characteristics of eddies at the sea surface, such as eddy number, lifetime and radius, from the model are comparable with those derived from the satellite altimetry data. The vertical profiles of the physical features of eddies are exposed from the statistical analysis of the three-dimensional eddy data set. For examples, more cyclonic eddies (CEs) are generated than anticyclonic eddies (AEs) in the depth above about 350 m and an opposite trend is presented below 350 m. The lifetimes of CEs and AEs are statistically equal and no significant variation at different vertical levels. Eddies in the central SCS have the largest size than in other areas and their sizes decrease with the increase in water depth. The relative vorticity amplitude of eddies decreases with the increase in the depth. There are three different types of eddies: bowl-shaped with the largest size at the surface, lens-shaped with the largest size in the middle and cone-shaped with the largest size at the bottom. Most of eddies are bowl-shaped eddies. The three types of eddies have different effects on the temperature and salinity profiles. Eddy genesis mechanisms are discussed and categorized into three types in the SCS: surface wind curl input, current interaction with the bottom topography and Kuroshio intrusion.

  19. Limited hip rotation and non-contact anterior cruciate ligament injury: a case-control study.

    PubMed

    Tainaka, Koji; Takizawa, Tsuyoshi; Kobayashi, Hiroyuki; Umimura, Masakazu

    2014-01-01

    Insufficient hip flexibility, a limiting factor for lower extremity rotation, can cause great rotational stress and consequent injury to the knees and ankles. A limited range of motion (ROM) of the hip might be associated with increased risk of non-contact anterior cruciate ligament (ACL) injury. We investigated the association between the risk of non-contact ACL injured student athletes and limitations of hip ROM. A case-control study was conducted at an orthopaedic clinic in Japan. Cases included all patients with non-contact ACL injury and without known marked alignment abnormalities who visited the orthopaedic clinic during 2000-2008. Controls included all patients with non-ACL sports-related injuries who visited the same clinic in 2000. The adjusted odds ratio of ROM of the hip was evaluated for non-contact ACL injury risk. These cases were 44 ACL cases and 123 controls aged 13-17 years. The odds ratios (ORs) of internal and external rotations of hip ROMs were adjusted for age, sex, BMI, type of sports and hip ROM (flexion, extension, adduction, abduction). The adjusted ORs for a 10° increase of the sum of the right and left internal hip rotations were 0.18 (95% confidence interval [CI], 0.10-0.34, p<0.0001), and 0.23 (95% CI, 0.14-0.39, p<0.0001) for external rotations, and the observed ORs were small. Data obtained from this small sample indicate that limited hip rotation ROMs in young athletes have the possibility of association with increased risk of non-contact ACL injury. III - case-control study. © 2013.

  20. Use of peritoneal dialysis after surgery for congenital heart disease in children.

    PubMed

    Santos, Catarina R; Branco, Patrícia Q; Gaspar, Augusta; Bruges, Margarida; Anjos, Rui; Gonçalves, Margarida S; Abecasis, Miguel; Meneses, Carlos; Barata, José D

    2012-01-01

    Acute kidney injury (AKI) is a common complication in children after surgery for congenital heart disease, and peritoneal dialysis (PD) is usually the renal replacement therapy (RRT) of choice, especially in very young children. The aim of the present study was to describe our experience of using PD to treat AKI after cardiac surgery. We retrospectively analyzed children 1 week to 16 years of age undergoing cardiac surgery during 2000-2008 and found the incidence of AKI treated with PD to be 2.3%. In the 23 patients treated with PD (13 male; average age: 29 ± 48.4 months; weight: 9.1 ± 8.1 kg), the indications for PD initiation were oliguria (n = 13), anuria (n = 9), and acidosis (n = 1). The average time between cardiac surgery and AKI was 4.8 ± 16.8 hours, and between AKI and PD initiation, it was 12 ± 16.8 hours. Patients were treated for a mean of 4.8 ± 3.8 days. Two patients developed peritonitis, and mechanical dysfunction of the PD catheter occurred in 1 patient. In-hospital mortality was 43.4%. Patients treated with PD weighed less (p = 0.004) and had longer bypass time (p = 0.004), inotrope use (p = 0.000), and mechanical ventilation (p = 0.000). However, in a regression analysis, only cardiopulmonary bypass time (odds ratio: 1.021; 95% confidence interval: 0.998 to 1.027; p = 0.032) remained predictive of a subsequent need for PD. We conclude that PD is an efficacious RRT for AKI in children undergoing cardiac surgery and that, in this setting, bypass time is the strongest predictor of a subsequent need for RRT.

  1. Hillslope-channel connectivity and local sediment budget in a Himalayan Valley (Kali Gandaki, Nepal)

    NASA Astrophysics Data System (ADS)

    Fort, Monique; Etienne, Cossart; Gilles, Arnaud-Fassetta

    2010-05-01

    In the confined Himalayan valleys and in a context of monsoon, contrasted climate, landslides interact with rivers immediately, causing channel diversions, short-lived dams and sediment traps. Yet, remnants of ancient landslides may play an important role in the location of present instabilities and sediment fluxes. We document here debris storages and interaction patterns with fluvial activity observed in the Middle Kali Gandaki river (Myagdi District, Nepal Himalayas). We focus on the Pairothapla-Talbagar landslide (about 10 x 10 exponent 6 m3) that dammed the Kali Gandaki probably a few centuries ago. On the basis of diachronic (1974-2000-2008) geomorphic surveys and mapping, and thanks to DEM facilities, we reconstructed the extent of the landslide deposits, characterized the material (debris avalanche, including >350 m3 blocks), estimated the volume of the resulting lake (9-14 x 10 exponent 6 m3), and of sedimentary wedges resulting from later superficial reworking and downstream redistribution of debris. We assess the recent evolution of the landslide mass. Current instabilities (rainfall triggered shallow landslides) are large enough to supply debris to the river and increase the density hence the transport capacity of the flow downstream; in turn armouring boulders may be set into motion again, hence accelerating erosion of the Talbagar landslide mass in a positive feedback. We estimate the volume of debris eroded and exported by the Kali Gandaki during the last three decades. We end up with the sedimentary budget related to this event. Comparison with other features, either older or more recent, observed along the middle Kali Gandaki valley suggests that landsliding plays the major role in the overall process of denudation and sediment transfer of the Higher Himalaya. When coupled with high fluvial activity, it considerably reduces the residence time of sediments in the temporary, spatially limited traps of the valley bottom and highly influences sediment

  2. Evaluation of hydrological balance in the eastern Amazon using a terrestrial ecosystem model, and satellite-based evapotranspiration (MODIS) and terrestrial water storage (GRACE)

    NASA Astrophysics Data System (ADS)

    Panday, P. K.; Coe, M. T.; Macedo, M.; Beck, P.

    2013-12-01

    High historical deforestation rates and a rapidly changing agricultural landscape may dramatically alter the energy and water balance of the eastern Amazon basin. Understanding the surface water dynamics and hydrological balance of the region is critical for accurately assessing the historical and potential future impacts of deforestation, land-use change, and land management practices. We examine the water balance of the Xingu river basin by combining the IBIS (Integrated Biosphere Simulator) terrestrial ecosystem model with satellite-based models of evapotranspiration (MOD16) and terrestrial water storage (GRACE). IBIS simulations were forced with prescribed climate to produce modeled evapotranspiration and runoff, which were then compared with MODIS evapotranspiration and observed discharge at Altamira (PA, Brazil). Results from both satellite observations and model simulations support earlier studies demonstrating that dry-season evapotranspiration is higher than wet-season evapotranspiration in the wetter forests of the northern Xingu basin, while the contrary is true in the seasonally dry forests of the southern Xingu. Seasonal variation in modeled soil water storage agrees with the GRACE measurements in both timing and magnitude. Soil moisture anomalies averaged over the Xingu basin suggest that annual changes in soil water storage account for a large part of the interannual variation in observed discharge. Field measurements of discharge and soil moisture in the southern Xingu also support the findings that changes in soil water storage drive inter-annual variations in river discharge. Figure 1. Comparison of observed discharge at Altamira (Pará, Brazil) against MODIS- derived P-E (PCRU-MODISET), IBIS simulated discharge, IBIS (PCRU-ETIBIS), and IBIS (PCRU-ETIBIS- Δ Soil moisture IBIS). The bottom panel shows annual basin precipitation from Climatic Research Unit (CRU) climatological data for the 2000-2008 period

  3. Trends in central nervous system tumor incidence relative to other common cancers in adults, adolescents, and children in the United States, 2000 to 2010.

    PubMed

    Gittleman, Haley R; Ostrom, Quinn T; Rouse, Chaturia D; Dowling, Jacqueline A; de Blank, Peter M; Kruchko, Carol A; Elder, J Bradley; Rosenfeld, Steven S; Selman, Warren R; Sloan, Andrew E; Barnholtz-Sloan, Jill S

    2015-01-01

    Time trends in cancer incidence rates (IR) are important to measure the changing burden of cancer on a population over time. The overall IR of cancer in the United States is declining. Although central nervous system tumors (CNST) are rare, they contribute disproportionately to mortality and morbidity. In this analysis, the authors examined trends in the incidence of the most common cancers and CNST between 2000 and 2010. The current analysis used data from the United States Cancer Statistics publication and the Central Brain Tumor Registry of the United States. Age-adjusted IR per 100,000 population with 95% confidence intervals and the annual percent change (APC) with 95% confidence intervals were calculated for selected common cancers and CNST overall and by age, sex, race/ethnicity, selected histologies, and malignancy status. In adults, there were significant decreases in colon (2000-2010: APC, -3.1), breast (2000-2010: APC, -0.8), lung (2000-2010: APC, -1.1), and prostate (2000-2010: APC, -2.4) cancer as well as malignant CNST (2008-2010: APC, -3.1), but a significant increase was noted in nonmalignant CNST (2004-2010: APC, 2.7). In adolescents, there were significant increases in malignant CNST (2000-2008: APC, 1.0) and nonmalignant CNST (2004-2010: APC, 3.9). In children, there were significant increases in acute lymphocytic leukemia (2000-2010: APC, 1.0), non-Hodgkin lymphoma (2000-2010: APC, 0.6), and malignant CNST (2000-2010: APC, 0.6). Surveillance of IR trends is an important way to measure the changing public health and economic burden of cancer. In the current study, there were significant decreases noted in the incidence of adult cancer, whereas adolescent and childhood cancer IR were either stable or increasing. © 2014 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society.

  4. Seasonal and interannual variability of climate and vegetation indices across the Amazon.

    PubMed

    Brando, Paulo M; Goetz, Scott J; Baccini, Alessandro; Nepstad, Daniel C; Beck, Pieter S A; Christman, Mary C

    2010-08-17

    Drought exerts a strong influence on tropical forest metabolism, carbon stocks, and ultimately the flux of carbon to the atmosphere. Satellite-based studies have suggested that Amazon forests green up during droughts because of increased sunlight, whereas field studies have reported increased tree mortality during severe droughts. In an effort to reconcile these apparently conflicting findings, we conducted an analysis of climate data, field measurements, and improved satellite-based measures of forest photosynthetic activity. Wet-season precipitation and plant-available water (PAW) decreased over the Amazon Basin from 1996-2005, and photosynthetically active radiation (PAR) and air dryness (expressed as vapor pressure deficit, VPD) increased from 2002-2005. Using improved enhanced vegetation index (EVI) measurements (2000-2008), we show that gross primary productivity (expressed as EVI) declined with VPD and PAW in regions of sparse canopy cover across a wide range of environments for each year of the study. In densely forested areas, no climatic variable adequately explained the Basin-wide interannual variability of EVI. Based on a site-specific study, we show that monthly EVI was relatively insensitive to leaf area index (LAI) but correlated positively with leaf flushing and PAR measured in the field. These findings suggest that production of new leaves, even when unaccompanied by associated changes in LAI, could play an important role in Basin-wide interannual EVI variability. Because EVI variability was greatest in regions of lower PAW, we hypothesize that drought could increase EVI by synchronizing leaf flushing via its effects on leaf bud development.

  5. Long-term patterns and short-term dynamics of stream solutes and suspended sediment in a rapidly weathering tropical watershed

    NASA Astrophysics Data System (ADS)

    Shanley, James B.; McDowell, William H.; Stallard, Robert F.

    2011-07-01

    The 326 ha Río Icacos watershed in the tropical wet forest of the Luquillo Mountains, northeastern Puerto Rico, is underlain by granodiorite bedrock with weathering rates among the highest in the world. We pooled stream chemistry and total suspended sediment (TSS) data sets from three discrete periods: 1983-1987, 1991-1997, and 2000-2008. During this period three major hurricanes crossed the site: Hugo in 1989, Hortense in 1996, and Georges in 1998. Stream chemistry reflects sea salt inputs (Na, Cl, and SO4), and high weathering rates of the granodiorite (Ca, Mg, Si, and alkalinity). During rainfall, stream composition shifts toward that of precipitation, diluting 90% or more in the largest storms, but maintains a biogeochemical watershed signal marked by elevated K and dissolved organic carbon (DOC) concentration. DOC exhibits an unusual "boomerang" pattern, initially increasing with flow but then decreasing at the highest flows as it becomes depleted and/or vigorous overland flow minimizes contact with watershed surfaces. TSS increased markedly with discharge (power function slope 1.54), reflecting the erosive power of large storms in a landslide-prone landscape. The relations of TSS and most solute concentrations with stream discharge were stable through time, suggesting minimal long-term effects from repeated hurricane disturbance. Nitrate concentration, however, increased about threefold in response to hurricanes then returned to baseline over several years following a pseudo first-order decay pattern. The combined data sets provide insight about important hydrologic pathways, a long-term perspective to assess response to hurricanes, and a framework to evaluate future climate change in tropical ecosystems.

  6. An integrative review and meta-synthesis of the scope and impact of intensive care liaison and outreach services.

    PubMed

    Endacott, Ruth; Eliott, Suzanne; Chaboyer, Wendy

    2009-12-01

    To determine activities and outcomes of intensive care unit Liaison Nurse/Outreach services. The review comprised two stages: (1) integrative review of qualitative and quantitative studies examining intensive care liaison/outreach services in the UK and Australia and (2) meta-synthesis using the Nursing Role Effectiveness Model as an a priori model. Acute ward patients are at risk of adverse events and patients recovering from critical illness are vulnerable to deterioration. Proactive and reactive strategies have been implemented to facilitate timely identification of patients at risk. Systematic review. A range of data bases was searched from 2000-2008. Studies were eligible for review if they included adults in any setting where intensive care unit Liaison Nurse or Outreach services were provided. From 1423 citations and 65 abstracts, 20 studies met the inclusion criteria. Intensive care liaison/outreach services had a beneficial impact on intensive care mortality, hospital mortality, unplanned intensive care admissions/re-admissions, discharge delay and rates of adverse events. A range of research methods were used; however, it was not possible to conclude unequivocally that the intensive care liaison/outreach service had resulted in improved outcomes. The major unmeasured benefit across all studies was improved communication pathways between critical care and ward staff. Outcomes for nurses in the form of improved confidence, knowledge and critical care skills were identified in qualitative studies but not measured. The varied nature of the intensive care liaison/outreach services reviewed in these studies suggests that they should be treated as bundled interventions, delivering a treatment package of care. Further studies should examine the impact of critical care support on the confidence and skills of ward nurses. Advanced nursing roles can improve outcomes for patients who are vulnerable to deterioration. The Nursing Role Effectiveness Model provides a

  7. Atrazine exposure in public drinking water and preterm birth.

    PubMed

    Rinsky, Jessica L; Hopenhayn, Claudia; Golla, Vijay; Browning, Steve; Bush, Heather M

    2012-01-01

    Approximately 13% of all births occur prior to 37 weeks gestation in the U.S. Some established risk factors exist for preterm birth, but the etiology remains largely unknown. Recent studies have suggested an association with environmental exposures. We examined the relationship between preterm birth and exposure to a commonly used herbicide, atrazine, in drinking water. We reviewed Kentucky birth certificate data for 2004-2006 to collect duration of pregnancy and other individual-level covariates. We assessed existing data sources for atrazine levels in public drinking water for the years 2000-2008, classifying maternal county of residence into three atrazine exposure groups. We used logistic regression to analyze the relationship between atrazine exposure and preterm birth, controlling for maternal age, race/ethnicity, education, smoking, and prenatal care. An increase in the odds of preterm birth was found for women residing in the counties included in the highest atrazine exposure group compared with women residing in counties in the lowest exposure group, while controlling for covariates. Analyses using the three exposure assessment approaches produced odds ratios ranging from 1.20 (95% confidence interval [CI] 1.14, 1.27) to 1.26 (95% CI 1.19, 1.32), for the highest compared with the lowest exposure group. Suboptimal characterization of environmental exposure and variables of interest limited the analytical options of this study. Still, our findings suggest a positive association between atrazine and preterm birth, and illustrate the need for an improved assessment of environmental exposures to accurately address this important public health issue.

  8. Levels of polychlorinated dibenzo-p-dioxins, dibenzofurans and dioxin-like polychlorinated biphenyls in placentas from the Spanish INMA birth cohort study.

    PubMed

    Fernandez, Mariana F; Parera, Jordi; Arrebola, Juan P; Marina, Loreto Santa; Vrijheid, Martine; Llop, Sabrina; Abalos, Manoli; Tardon, Adonina; Castaño, Argelia; Abad, Esteban; Olea, Nicolas

    2012-12-15

    Because fetuses are considered significantly more sensitive to various environment toxicants, there is a need for continuous biomonitoring of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls PCBs (DL-PCBs) to assess their impact on this susceptible population. The aim of this study was to assess the concentration of PCDD/Fs and DL-PCBs in placenta samples from women participating in the Spanish Environment and Childhood (INMA) birth cohort study and to evaluate whether maternal and child characteristics predict placenta concentrations of these pollutants. The presence of PCDD/Fs and DL-PCBs was investigated in 50 placenta samples selected at random in the recruitment period 2000-2008. Multivariable regression models were constructed. Mothers had a mean age at delivery of 30.7 years (18.0-38.0 years), pre-pregnancy BMI of 23.3 kg/m² (18.0-40.2 kg/m²), and 31% were smokers. Median total concentrations of PCDD/Fs and DL-PCBs were 6.9 pg WHO-TEQ/g lipid and 2.1 pg WHO-TEQ/g lipid, respectively. In comparison to the few previous studies in placenta, total TEQ levels were among the lowest recorded in comparable general populations. The congener distribution pattern and the frequencies and concentrations of PCDD/F and DL-PCB congeners were similar to previous reports in placenta. PCDD/F and DL-PCB exposure was related to the age of the mother and the year of the delivery. Although placental concentrations cannot be considered wholly appropriate predictors for evaluating fetal exposure to these contaminants, they can provide a good indication of both maternal and infant prenatal and postnatal exposure and can be used as a proxy for fetal exposure. Copyright © 2012 Elsevier B.V. All rights reserved.

  9. Associations between outdoor temperature and markers of inflammation: a cohort study

    PubMed Central

    2010-01-01

    Background Associations between ambient temperature and cardiovascular mortality are well established. This study investigated whether inflammation could be part of the mechanism leading to temperature-related cardiovascular deaths. Methods The study population consisted of a cohort of 673 men with mean age of 74.6 years, living in the greater Boston area. They were seen for examination roughly every 4 years, and blood samples for inflammation marker analyses were drawn in 2000-2008 (total of 1254 visits). We used a mixed effects model to estimate the associations between ambient temperature and a variety of inflammation markers (C-reactive protein, white blood cell count, soluble Vascular Cell Adhesion Molecule-1, soluble Intercellular Adhesion Molecule-1, tumor necrosis factor alpha, and interleukins -1β, -6 and -8). Random intercept for each subject and several possible confounders, including combustion-related air pollution and ozone, were used in the models. Results We found a 0 to 1 day lagged and up to 4 weeks cumulative responses in C-reactive protein in association with temperature. We observed a 24.9% increase [95% Confidence interval (CI): 7.36, 45.2] in C-reactive protein for a 5°C decrease in the 4 weeks' moving average of temperature. We observed similar associations also between temperature and soluble Intercellular Adhesion Molecule-1 (4.52%, 95% CI: 1.05, 8.10, over 4 weeks' moving average), and between temperature and soluble Vascular Cell Adhesion Molecule-1 (6.60%, 95% CI: 1.31, 12.2 over 4 weeks' moving average). Penalized spline models showed no deviation from linearity. There were no associations between temperature and other inflammation markers. Conclusions Cumulative exposure to decreased temperature is associated with an increase in inflammation marker levels among elderly men. This suggests that inflammation markers are part of intermediate processes, which may lead to cold-, but not heat-, related cardiovascular deaths. PMID:20653951

  10. Estimation of annual forest evapotranspiration from a coniferous plantation watershed in Japan (2): Comparison of eddy covariance, water budget and sap-flow plus interception loss

    NASA Astrophysics Data System (ADS)

    Shimizu, Takanori; Kumagai, Tomo'omi; Kobayashi, Masahiro; Tamai, Koji; Iida, Shin'ichi; Kabeya, Naoki; Ikawa, Reo; Tateishi, Makiko; Miyazawa, Yoshiyuki; Shimizu, Akira

    2015-03-01

    Evapotranspiration (ET) was estimated from a planted coniferous forest in southwestern Japan by applying three methods: the eddy covariance method; the measurement of rainfall (P) and runoff (Q) in a small watershed; and a combination of rainfall interception loss (IC), upper canopy transpiration based on a sap-flux density measurement in Japanese cedar (Cryptomeria Japonica D. Don) stands (EUC), and modeled sub-canopy ET (ESC). After inverse multiplication of the energy imbalance ratio, ET by the eddy covariance method (ETEC) was 839.9 mm in 2007 and 811.8 mm in 2008. The yearly values of P-Q were partially affected by P in the previous autumn. After continuous data collection for more than 5 years, P-Q became stable. The 9-year (2000-2008) average P-Q, which was considered most reliable in this study, was 897.5 mm y-1. The cumulative ETEC during the daylight hours from the right stream bank, covered mainly with large Japanese cedars, was 894.1 mm from April 2007 to March 2008. The value was almost the same as that calculated as the components sum (ETCOMP = IC + EUC + ESC: 911.4 mm), and the comparison suggested that the annual totals of ETEC with an energy imbalance correction provide a reliable estimate of ET in a forest stand on a complex topography. Spatial variation in the watershed was likely caused by differences in soil water retention at each slope position. The slight difference in annual ETEC in 2007 compared with 2008 was attributed to differences in the radiative energy input. In the monthly-weekly analysis, ETCOMP was frequently higher than ETEC after heavy rainfall, while ETEC was higher under dry conditions and during active ET. Even under dry canopy conditions, daily ETEC was often higher than EUC + ESC. The results suggested a time-lag in evaporation from the ecosystem and/or under-estimated ETEC after rainfall.

  11. Comorbidity prevalence, healthcare utilization, and expenditures of Medicaid enrolled adults with autism spectrum disorders.

    PubMed

    Vohra, Rini; Madhavan, Suresh; Sambamoorthi, Usha

    2016-10-20

    A retrospective data analysis using 2000-2008 three state Medicaid Analytic eXtract was conducted to examine the prevalence and association of comorbidities (psychiatric and non-psychiatric) with healthcare utilization and expenditures of fee-for-service enrolled adults (22-64 years) with and without autism spectrum disorders (International Classification of Diseases, Ninth Revision-clinical modification code: 299.xx). Autism spectrum disorder cases were 1:3 matched to no autism spectrum disorder controls by age, gender, and race using propensity scores. Study outcomes were all-cause healthcare utilization (outpatient office visits, inpatient hospitalizations, emergency room, and prescription drug use) and associated healthcare expenditures. Bivariate analyses (chi-square tests and t-tests), multinomial logistic regressions (healthcare utilization), and generalized linear models with gamma distribution (expenditures) were used. Adults with autism spectrum disorders (n = 1772) had significantly higher rates of psychiatric comorbidity (81%), epilepsy (22%), infections (22%), skin disorders (21%), and hearing impairments (18%). Adults with autism spectrum disorders had higher mean annual outpatient office visits (32ASD vs 8noASD) and prescription drug use claims (51ASD vs 24noASD) as well as higher mean annual outpatient office visits (US$4375ASD vs US$824noASD), emergency room (US$15,929ASD vs US$2598noASD), prescription drug use (US$6067ASD vs US$3144noASD), and total expenditures (US$13,700ASD vs US$8560noASD). The presence of a psychiatric and a non-psychiatric comorbidity among adults with autism spectrum disorders increased the annual total expenditures by US$4952 and US$5084, respectively.

  12. Multi-locus variable-number tandem repeat analysis of Chinese Brucella strains isolated from 1953 to 2013.

    PubMed

    Tian, Guo-Zhong; Cui, Bu-Yun; Piao, Dong-Ri; Zhao, Hong-Yan; Li, Lan-Yu; Liu, Xi; Xiao, Pei; Zhao, Zhong-Zhi; Xu, Li-Qing; Jiang, Hai; Li, Zhen-Jun

    2017-05-02

    Brucellosis was a common human and livestock disease caused by Brucella strains, the category B priority pathogens by the US Center for Disease Control (CDC). Identified as a priority disease in human and livestock populations, the increasing incidence in recent years in China needs urgent control measures for this disease but the molecular background important for monitoring the epidemiology of Brucella strains at the national level is still lacking. A total of 600 Brucella isolates collected during 60 years (from 1953 to 2013) in China were genotyped by multiple locus variable-number tandem repeat analysis (MLVA) and the variation degree of MLVA11 loci was calculated by the Hunter Gaston Diversity Index (HGDI) values. The charts and map were processed by Excel 2013, and cluster analysis and epidemiological distribution was performed using BioNumerics (version 5.1). The 600 representative Brucella isolates fell into 104 genotypes with 58 singleton genotypes by the MLVA11 assay, including B. melitensis biovars 2 and 3 (five main genotypes), B. abortus biovars 1 and 3 (two main genotypes), B. suis biovars 1 and 3 (three main genotypes), and B. canis (two main genotypes) respectively. While most B. suis biovar 1 and biovar 3 were respectively found in northern provinces and southern provinces, B. melitensis and B. abortus strains were dominant in China. Canine Brucellosis was only found in animals without any human cases reported. Eight Brucellosis epidemic peaks emerged during the 60 years between 1953 and 2013: 1955 - 1959, 1962 - 1969, 1971 - 1975, 1977 - 1983, 1985 - 1989, 1992 - 1997, 2000 - 2008 and 2010 - 2013 in China. Brucellosis has its unique molecular epidemiological patterns with specific spatial and temporal distribution according to MLVA. IDOP-D-16-00101.

  13. Eight years of building community partnerships and trust: the UCLA family medicine community-based participatory research experience.

    PubMed

    Moreno, Gerardo; Rodríguez, Michael A; Lopez, Glenn A; Bholat, Michelle A; Dowling, Patrick T

    2009-10-01

    Acknowledging the growing disparities in health and health care that exist among immigrant families and minority populations in large urban communities, the UCLA Department of Family Medicine (DFM) sought a leadership role in the development of family medicine training and community-based participatory research (CBPR). Performing CBPR requires that academic medicine departments build sustainable and long-term community partnerships. The authors describe the eight-year (2000-2008) process of building sustainable community partnerships and trust between the UCLA DFM and the Sun Valley community, located in Los Angeles County.The authors used case studies of three research areas of concentration (asthma, diabetes prevention, and establishing access to primary care) to describe how they established community trust and sustained long-term community research partnerships. In preparing each case study, they used an iterative process to review qualitative data.Many lessons were common across their research concentration areas. They included the importance of (1) having clear and concrete community benefits, (2) supporting an academic-community champion, (3) political advocacy, (4) partnering with diverse organizations, (5) long-term academic commitment, and (6) medical student involvement. The authors found that establishing a long-term relationship and trust was a prerequisite to successfully initiate CBPR activities that included an asthma school-based screening program, community walking groups, and one of the largest school-based primary care clinics in the United States.Their eight-year experience in the Sun Valley community underscores how academic-community research partnerships can result in benefits of high value to communities and academic departments.

  14. Sickle cell disease incidence among newborns in New York State by maternal race/ethnicity and nativity.

    PubMed

    Wang, Ying; Kennedy, Joseph; Caggana, Michele; Zimmerman, Regina; Thomas, Sanil; Berninger, John; Harris, Katharine; Green, Nancy S; Oyeku, Suzette; Hulihan, Mary; Grant, Althea M; Grosse, Scott D

    2013-03-01

    Sickle cell disease is estimated to occur in 1:300-400 African-American births, with higher rates among immigrants from Africa and the Caribbean, and is less common among Hispanic births. This study determined sickle cell disease incidence among New York State newborns stratified by maternal race/ethnicity and nativity. Newborns with confirmed sickle cell disease born to New York State residents were identified by the New York State newborn screening program for the years 2000-2008 and matched to birth records to obtain birth and maternal information. Annual incidence rates were computed and bivariate analyses were conducted to examine associations with maternal race/ethnicity and nativity. From 2000 to 2008, 1,911 New York State newborns were diagnosed with sickle cell disease and matched to the birth certificate files. One in every 1,146 live births was diagnosed with sickle cell disease. Newborns of non-Hispanic black mothers accounted for 86% of sickle cell disease cases whereas newborns of Hispanic mothers accounted for 12% of cases. The estimated incidence was 1:230 live births for non-Hispanic black mothers, 1:2,320 births for Hispanic mothers, and 1:41,647 births for non-Hispanic white mothers. Newborns of foreign-born non-Hispanic black mothers had a twofold higher incidence of sickle cell disease than those born to US-born non-Hispanic black mothers (P < 0.001). This study provides the first US estimates of sickle cell disease incidence by maternal nativity. Women born outside the United States account for the majority of children with sickle cell disease born in New York State. Such findings identify at-risk populations and inform outreach activities that promote ongoing, high-quality medical management to affected children.

  15. The association of ethnic minority density with late entry into antenatal care in the Netherlands.

    PubMed

    Posthumus, Anke G; Schölmerich, Vera L N; Steegers, Eric A P; Kawachi, Ichiro; Denktaş, Semiha

    2015-01-01

    In the Netherlands, non-Western ethnic minority women make their first antenatal visit later than native Dutch women. Timely entry into antenatal care is important as it provides the opportunity for prenatal screening and the detection of risk factors for adverse pregnancy outcomes. In this study we explored whether women's timely entry is influenced by their neighborhood. Moreover, we assessed whether ethnic minority density (the proportion of ethnic minorities in a neighborhood) influences Western and non-Western ethnic minority women's chances of timely entry into care differently. We hypothesized that ethnic minority density has a protective effect against non-Western women's late entry into care. Data on time of entry into care and other individual-level characteristics were obtained from the Netherlands Perinatal Registry (2000-2008; 97% of all pregnancies). We derived neighborhood-level data from three other national databases. We included 1,137,741 pregnancies of women who started care under supervision of a community midwife in 3422 neighborhoods. Multi-level logistic regression was used to assess the associations of individual and neighborhood-level determinants with entry into antenatal care before and after 14 weeks of gestation. We found that neighborhood characteristics influence timely entry above and beyond individual characteristics. Ethnic minority density was associated with a higher risk of late entry into antenatal care. However, our analysis showed that for non-Western women, living in high ethnic minority density areas is less detrimental to their risk of late entry than for Western women. This means that a higher proportion of ethnic minority residents has a protective effect on non-Western women's chances of timely entry into care. Our results suggest that strategies to improve timely entry into care could seek to create change at the neighborhood level in order to target individuals likely of entering care too late.

  16. Admission to hospital with community-onset bloodstream infection during the 'after hours' is not associated with an increased risk for death.

    PubMed

    Laupland, Kevin B

    2010-12-01

    Several studies conducted in diverse patient populations have found that patients presenting with acute illness during weekends or evening/nights are at increased risk for death. This study was conducted to examine whether patients with community-onset bloodstream infections who are admitted during evenings, nights, and weekends suffer increased mortality rates. All residents within the Calgary area who had first admissions with community-onset bloodstream infections during 2000-2008 were included. One thousand eight hundred and seventy-eight (27%) patients were admitted on a weekend. Among all admissions, 2753 (40%) were during the hours of 08:00-17:59, 1996 (29%) during 18:00-22:59, and 2174 (31%) during 23:00-07:59. More than two-thirds (n = 4867; 70%) of cases were admitted during the 'after hours' (evenings, nights, and/or weekends). The 30-day case-fatality rate was 13% (882/6923) and did not significantly vary between daytime (364/2753; 13%), evening (246/1996; 12%), and night (272/2174; 13%) admissions (p = 0.6), or with patients admitted on weekends as compared to weekdays (252/1878 (13%) vs. 630/5045 (12%); p = 0.3). Admission during the after hours (weekends and evenings/nights) was not associated with increased risk for death in logistic regression analysis (odds ratio 0.99, 95% confidence interval 0.83-1.16; p = 0.88). Admission with community-onset bloodstream infection during the after hours is not associated with adverse outcome in this region.

  17. Determining Stroke’s Rank as a Cause of Death using Multi-Cause Mortality Data

    PubMed Central

    Burke, James F; Lisabeth, Lynda D; Brown, Devin L; Reeves, Matthew J; Morgenstern, Lewis B

    2013-01-01

    Background Stroke has fallen from the second to the fourth leading cause of death in the United States without large declines in stroke incidence or case fatality. We explored whether this decline may be attributable to changes in mortality attribution methodology. Methods Multi-cause mortality files from 2000-2008 were used to compare changes in reporting of stroke as underlying cause of death (UCOD) with changes in death certificates reporting any mention (AMCOD) of stroke. In addition, the UCOD/AMCOD ratio was calculated for the six leading organ and disease-specific causes of death. If stroke mortality is underestimated by the system of mortality attribution we hypothesized that we would find: 1. A greater decline in stroke as UCOD than as AMCOD 2. A decline in the UCOD/AMCOD ratio compared to other causes of death. Results Age-adjusted death rates for stroke as UCOD (61 per 100,000 in 2000 vs. 41 in 2008) and AMCOD (102 per 100,000 vs. 68) both declined by 33%. The ratio of UCOD to AMCOD for stroke did not change over time (0.595 in 2000 vs. 0.598 in 2008). Changes in UCOD/AMCOD ratio for the diagnoses that surpassed stroke as UCOD were too small (no change for lung cancer, and a slight increase from 0.49 to 0.52 for chronic lower respiratory diseases) to explain stroke’s decline as UCOD. Conclusion Changes in mortality attribution methodology are not likely responsible for stroke’s decline as a leading cause of death. The discordant trends in incidence, case fatality and mortality require further study. PMID:22821613

  18. Recent trends in global methane emissions inferred from 30-years of surface CH4 and δ13C-CH4 measurements

    NASA Astrophysics Data System (ADS)

    Karmakar, S.; Butenhoff, C. L.; Rice, A. L.; Lofdahl, D. B.; Khalil, A. K.

    2015-12-01

    Methane (CH4) is the second most important greenhouse gas after carbon dioxide. Quantitative understanding of the global CH4 budget is important in order to predict future contributions of global warming and to develop effective strategies for its mitigation. After a decade-long period of decreasing growth rates, atmospheric CH4 concentrations have risen in recent years raising concerns about its long-term stability. Despite much study there is no clear consensus about the causes of this increase. Some bottom-up inventories suggest that fugitive emissions from the fossil fuel industry may be increasing though there are considerable uncertainties in these estimates due in part to the variable nature of this source. To better understand the changing budget of atmospheric CH4, we performed a time-dependent retrieval of CH4 fluxes spanning nearly 30 years using global surface and isotopic CH4 measurements. An earlier inversion from our group suggested that fugitive fossil fuel emissions increased from 2000-2008, contributing to the recent rise. Here we extend this study to year 2015 using the most recent NOAA Global Monitoring Division (GMD) CH4 measurements and available δ13C -CH4 data along with a higher resolution version of the chemical transport model GEOS-Chem (2ox2.5o). The higher resolution grid allowed us to extract more information from the observations due to the improved ability of the model to simulate CH4 at each station and the decreased need to aggregate neighboring stations. This in turn increased the error reduction between the a priori and posterior emissions leading to more accurate estimates of the retrieved fluxes and improved understanding of the drivers underlying the current atmospheric record.

  19. Relative mortality among criminals in Norway and the relation to drug and alcohol related offenses.

    PubMed

    Skardhamar, Torbjørn; Skirbekk, Vegard

    2013-01-01

    Registered offenders are known to have a higher mortality rate, but given the high proportion of offenders with drug-addiction, particularly among offenders with a custodial sentence, higher mortality is expected. While the level of overall mortality compared to the non-criminal population is of interest in itself, we also estimate the risk of death by criminal records related to substance abuse and other types of criminal acts, and separate between those who receive a prison sentence or not. Age-adjusted relative risks of death for 2000-2008 were studied in a population based dataset. Our dataset comprise the total Norwegian population of 2.9 million individuals aged 15-69 years old in 1999, of whom 10% had a criminal record in the 1992-1999 period. Individuals with a criminal record have twice the relative risk (RR) of death of the control group (non-offenders). Males with a record of use/possession of drugs and a prison record have an 11.9 RR (females, 15.6); males with a drug record but no prison record have a 6.9 RR (females 10.5). Males imprisoned for driving under the influence of substances have a 4.4 RR (females 5.6); males with a record of driving under the influence but no prison sentence have a 3.2 RR (females 6.5). Other male offenders with a prison record have a 2.8 RR (females 3.7); other male offenders with no prison record have a 1.7 RR (females 2.3). Significantly higher mortality was found for people with a criminal record, also for those without any record of drug use. Mortality is much higher for those convicted of substance-related crimes: more so for drug- than for alcohol-related crimes and for women.

  20. The Effects of Open versus Closed Kinetic Chain Exercises on Patients with ACL Deficient or Reconstructed Knees: A Systematic Review

    PubMed Central

    Waddell, Janessa; Hoogenboom, Barbara

    2010-01-01

    Background There is no consensus among the existing published evidence as to whether closed kinetic chain (CKC) or open kinetic chain (OKC) exercises should be the intervention of choice following an anterior cruciate ligament (ACL) injury or reconstruction. The commonly held belief has been that OKC exercises cause increased strain on the ACL as well as increased joint laxity and anterior tibial translation. Objective To investigate the effects of OKC and CKC exercises on the knees of patients with ACL deficiency or reconstruction. Data Sources MEDLINE, ProQuest Medical Library, and CINAHL Study Selection Six articles were chosen for inclusion in the systematic review. The authors narrowed 50 articles down to 6 by review of titles and abstracts. Included articles were randomized controlled trials written in English, published during 2000-2008, that evaluated the effects of OKC and CKC exercises on ACL deficient or reconstructed knees. Data Extraction Quality of the included studies was defined by the PEDro scale1, which has been found to be reliable.2 Data Synthesis Scores on the PEDro scale1 ranged from 4-6/10. One article found positive significant effects with inclusion of OKC exercises in the rehabilitation program and another found significant benefits with combining OKC and CKC exercises. CKC exercises alone were not found by any studies to be superior to OKC exercises. Conclusion These studies reveal favorable results for utilization of both open and closed kinetic chain exercises for intervention with ACL deficient or reconstructed knees. However, further research needs to be completed. PMID:21589664

  1. Trends in acute myocardial infarction hospitalization rates for US States in the CDC tracking network.

    PubMed

    Talbott, Evelyn O; Rager, Judith R; Brink, Luann L; Benson, Stacey M; Bilonick, Richard A; Wu, Wen Chi; Han, Yueh-Ying

    2013-01-01

    We examined temporal trends, spatial variation, and gender differences in rates of hospitalization due to acute myocardial infarction. We used data from the Centers for Disease Control National Environmental Public Health Tracking Network to evaluate temporal trends, geographic variation, and gender differences in 20 Environmental Public Health Tracking Network states from 2000 to 2008. A longitudinal linear mixed effects model was fitted to the acute myocardial infarction hospitalization rates for the states and counties within each state to examine the overall temporal trend. There was a significant overall decrease in age-adjusted acute myocardial infarction hospitalization rates between 2000 and 2008, with most states showing over a 20% decline during the period. The ratio of male/female rates for acute myocardial infarction hospitalization rates remained relatively consistent over time, approximately two-fold higher in men compared to women. A large geographic variability was found for age-adjusted acute myocardial infarction hospitalization rates, with the highest rates found in the Northeastern states. Results of two ecological analyses revealed that the NE region remained significantly associated with increased AMI hospitalization rates after adjustment for socio-demographic factors. This investigation is one of the first to explore geographic differences in AMI age adjusted hospital rates in individuals 35+ years of age for 2000-2008. We showed a decreasing trend in AMI hospitalization rates in men and women. A large geographic variability in rates was found with particularly higher rates in the New England/Mid-Atlantic region of the US and lower rates in the mountain and Pacific states of the tracking network. It appeared that over time this disparity in rates became less notable.

  2. Grassland and Cropland Net Ecosystem Production of the U.S. Great Plains

    NASA Astrophysics Data System (ADS)

    Howard, D. M.; Wylie, B. K.; Ji, L.; Gilmanov, T. G.; Zhang, L.

    2014-12-01

    At observation sites throughout the world, carbon dioxide (CO2) levels and other ecosystem resources are measured by instruments known as flux towers. Although flux towers only measure the surrounding vicinity or spatial footprint of their placement ecosystem, the data recorded at these towers can be up-scaled to much greater levels through the use of comprehensive remote sensing data and advanced computer modeling. The purpose of this study was to develop ecological net ecosystem production (NEP) models capable of producing weekly cropland and grassland NEP maps of the U.S. Great Plains at 250 meter resolution for 2000 - 2008. Separate NEP regression tree models were developed for each land cover type (cropland and grassland) with 15 flux towers supporting the grassland model and 13 towers supporting the cropland model. The NEP regression tree models were established through training based on data from the supporting flux towers, remote sensing data, and other biogeophysical inputs. Map results of this study indicate, as anticipated, grassland ecosystems generally perform as net carbon (C) sinks, absorbing and storing C from the atmosphere, and conversely, croplands generally as net C sources (crop yields were not taken into account), releasing C, in the form of CO2, into the atmosphere. The models were evaluated by implementing a leave-one-out cross validation method, which withholds data form one particular year or site for testing a model developed with the remaining data. The cropland model validation analysis received an average Pearson's correlation coefficient (r) of 0.85 for the yearly validation and an average r = 0.73 for the site withholding. The grassland model validation analysis received an average r = 0.86 for the yearly validation and an average r = 0.83 for the site withholding.

  3. Life Course Experiences, Pain and Suffering: A Case Study of an Older Mexican American Woman with Mobility Impairment

    PubMed Central

    Walker, Janiece L.; Harrison, Tracie C.; Hendrickson, Sherry G.

    2012-01-01

    There is a dearth of literature examining how adversity shapes the experiences of pain and/or suffering in a middle aged Mexican American women. The purpose of this qualitative descriptive study was to understand pain and suffering from a life course perspective as described by a Mexican American woman aging with early onset mobility impairment. This Hispanic woman experienced episodes of abuse and rejection over the life course, which may have significantly influenced her pain and suffering experience in adulthood. This adds to the literature on how adversity influences later life pain experience and provides insight on why pharmacological treatment alone may not be as successful as a holistic intervention. Hay escasez de literatura que examine cómo la adversidad da forma a las experiencias de dolor y / o sufrimiento en mujeres mexicana-americana mayores de edad. El propósito de este estudio descriptivo cualitativo fue comprender el dolor y el sufrimiento desde una perspectiva de ciclo de vida como descrito por una mujer mexicana-americana envejeciendo con inicio temprano de deterioro de movilidad. Esta Latina experimentó episodios de maltrato y rechazo, que se percibió haber afectado su experiencia de dolor y sufrimiento luego como adulta. Este estudio aumenta la literatura sobre cómo la adversidad influya la experiencia de dolor más tarde en la vida, y nos permite comprender mejor como el tratamiento farmacológico por sí solo no es tan exitoso como pueda ser una intervención integral. PMID:24830728

  4. PubMed

    Ysunza, Alberto M; Diez-Urdanivia, Silvia; Pérez-Gil, Sara E

    2016-06-08

    En este artículo presentamos el proyecto de capacitación llevado a cabo en comunidades de la sierra y costa de Oaxaca, México, desde 1991, por el Centro de Capacitación Integral para Promotores Comunitarios (CECIPROC). La decisión de hacer este trabajo en Oaxaca responde a que ese estado ocupa uno de los primeros lugares de marginación y de desnutrición en menores de 5 años. El objetivo es describir un modelo de capacitación y compartir parte de las experiencias derivadas, tanto del modelo como del trabajo realizado en las distintas áreas (nutrición y alimentación, salud comunitaria, ecología y etnobotánica, y educación y organización), por promotores mujeres y hombres en sus comunidades.La experiencia obtenida en 24 años muestra la factibilidad técnica y social del proyecto en el ámbito de la salud, el reconocimiento social del proyecto del CECIPROC como un organismo civil que ha aportado alternativas como solución a la problemática de salud, el hacer suyo el proyecto por algunos promotores y los diferentes obstáculos a los que se ha enfrentado. Enfatizamos el hecho de que la situación socioeconómica y política prevaleciente en el estado de Oaxaca es una limitante para el buen desarrollo de los programas colectivos de salud, e insistimos en la necesidad de compartir nuestras experiencias para que puedan ser utilizadas en la planificación y ejecución de otros proyectos.

  5. Una visita en Sud America

    NASA Astrophysics Data System (ADS)

    1982-09-01

    Oisfrute de una estadfa en el Hotel La Silla, el mejor hotel de Sud America con su tan unica atmosfera extraterrestre! Los espera su calificado personal de experimentados hoteleros, jefes de cocina, etc., ansiosos todos de satisfacer sus deseos hasta el mas mfnimo detalle. Naturalmente nuestro espacioso restaurant de tres estrellas ofrece un completo surtido de exquisitas comidas y deliciosos tragos (conocedores usualmente eligen "Oelicia Orion" 0 "Centauro Especial"). EI servicio cempleto durante 24 horas incluye nuestra ya mundialmente famosa "Cena de medianoche para los miradores de estrellas", por eso - no olvide: No pierda la oportunidad de una estadfa en EL HOTEL LA SILLA - una experiencia maravillosa!

  6. El aprendizaje significativo en las ciencias al participar en proyectos de investigacion cientifica

    NASA Astrophysics Data System (ADS)

    Mora Polanco, Miguelena

    La ciencia es el eje fundamental a traves del cual se desarrollan las habilidades necesarias para el pensar cientifico que va a la busqueda del conocimiento cientifico. La intencion de este estudio fue indagar en el tema de investigacion cientifica desde el punto de vista de los participantes en los siguientes aspectos relacionados con la experiencia de investigacion cientifica: a) conceptos, b) proceso, c) destrezas y d) disposicion. Tambien se analizaron: a) las perspectivas del metodo cientifico, b) la estrategia de ensenanza, c) la cultura cientifica y d) la exposicion del proyecto investigativo en la Feria Cientifica; como parte del aprendizaje significativo de la ciencias de los participantes. Esta investigacion cualitativa propuso como diseno el estudio de caso. Los aspectos relacionados a la experiencia de participar en proyecto de investigacion cientifica son el fenomeno o caso bajo estudio. En el estudio participaron cinco (5) estudiantes egresados de escuela publica o privada que cursaban hasta el tercer ano de estudios universitarios, conducentes a un bachillerato en educacion secundaria en ciencias o en ciencias naturales. Las tecnicas utilizadas para recopilar los datos fueron: analisis de documentos del DEPR, revision de artefactos y entrevistas profundas. Para el analisis de los datos de las entrevistas se utilizo el modelo de Wolcott (1994). Del analisis de documentos del DEPR se identificaron areas a mejorar en las guias de las cartas circulares con relacion a la investigacion escolar y la feria cientifica. El analisis de los artefactos proveyo evidencia de como los internados, simposios e investigaciones fomentan el que los estudiantes se superen en el aspecto cognitivo, se conviertan en creadores del conocimiento, al hacer suyo los conceptos para poder explicarlos al publico. De las entrevistas los participantes manifestaron que la experiencia de investigacion fue una de aprendizaje significativo que los marco para toda la vida y les expandio su

  7. Learning qualitative aspects of the ethics of biomedical and psychosocial research program of the Interdisciplinary Center for Studies on Bioethics, University of Chile1

    PubMed Central

    Rodríguez, Eduardo

    2012-01-01

    El presente trabajo reflexiona sobre la experiencia de 10 años en procesos de aprendizaje grupal y adquisición de competencias, de los participantes en el Programa de Ética de la Investigación Biomédica y Psicosocial del Centro Interdisciplinario de Estudios en Bioética de la Universidad de Chile, Fogarty Grant R25TW6056. Considera el papel de la bioética en la formación en su carácter transdisciplinario. PMID:22833694

  8. [Hospital readmissions in Portugal over the last decade].

    PubMed

    Sousa-Pinto, Bernardo; Gomes, Ana Rita; Oliveira, Andreia; Ivo, Carlos; Costa, Gustavo; Ramos, João; Silva, Joel; Carneiro, Maria Carolina; Domingues, Maria João; Cunha, Maria João; Costa-Pereira, Altamiro Da; Freitas, Alberto

    2013-01-01

    Introdução: Os reinternamentos hospitalares estão associados a um incremento das despesas com a saúde e da mortalidade intrahospitalar. Neste trabalho, pretende-se caracterizar os reinternamentos hospitalares não-planeados, ocorridos num período de 30 dias após alta, de acordo com a sua Grande Categoria Diagnóstica, contexto hospitalar e características demográficas dos utentes, bem como estimar as taxas de mortalidade associadas. Pretende-se também estudar a evolução da taxa de reinternamentos na última década (2000-2008). Procurar-se-á ainda caracterizar os reinternamentos por insuficiência cardíaca.Material e Métodos: Procedeu-se à análise estatística da base de dados de internamentos hospitalares públicos fornecida pelaAutoridade Central do Sistema de Saúde. Recorreu-se aos testes do qui-quadrado e de tendência para comparação de taxas dereinternamentos.Resultados: Das 5 514 331 hospitalizações não-planeadas no período em estudo, 4,1% corresponderam a reinternamentos hospitalares. Entre 2000 e 2008, a taxa de reinternamentos hospitalares aumentou continuamente de 3,0% para 4,7%. A mortalidade hospitalar foi significativamente maior entre os episódios de reinternamento (9,5%) do que nos restantes episódios (5,6%), p < 0,001. A taxa de reinternamentos foi significativamente maior em homens (4,5% versus 3,9% nas mulheres, p < 0,001) e doentes mais velhos (2,6% nas crianças e 5,3% nos idosos), sendo menor na região de Lisboa (2,7%) e nos hospitais centrais (3,0%, p < 0,001). Para os episódios de insuficiência cardíaca, foi obtida uma taxa de reinternamentos de 6,7%.Discussão e Conclusão: Em termos gerais, as diferenças encontradas são similares às descritas noutros Países Ocidentais. Os episódios de reinternamento, cujas taxas têm vindo a aumentar em Portugal, estão associados a maior mortalidade intra-hospitalar.

  9. Traffic-related air quality trends in São Paulo, Brazil

    NASA Astrophysics Data System (ADS)

    Pérez-Martínez, Pedro José; Fátima Andrade, María.; Miranda, Regina Maura

    2015-06-01

    making a greater contribution during the 2000-2008 period, whereas HDVs made a greater contribution during the 2009-2013 period, and decreases in NOx emissions resulted in increases in O3 observations.

  10. Reducing Uncertainty in Characterization of the Vadose Zone for Modeling Groundwater Vulnerability

    NASA Astrophysics Data System (ADS)

    Li, R.; Merchant, J.; Chen, X.; Oglesby, R. J.; Gosselin, D. C.

    2009-12-01

    Groundwater is the principal source of drinking water for nearly two billion people. Modeling aquifer susceptibility to pollution is critical for implementing programs to protect groundwater quality. Such models typically involve geospatial analysis of the inter-relationships between landscape characteristics (e.g. depth-to-water, soils, aquifer properties, and recharge) that impact pollution risks. It has, however, been especially difficult to characterize the vadose zone, the unsaturated zone between the soil surface and the water table. Working in the Elkhorn River Basin, Nebraska, we demonstrate a novel GIS approach for characterizing the vadose zone such that the uncertainty in groundwater pollution risk assessment modeling is reduced. The method is implemented using standard, widely-available national and state geospatial data. The groundwater level data from 2000-2008 in the study area, retrieved by using Microsoft Excel based web-query from USGS Active Groundwater Level Network, were processed and stored in a geodatabase with uniform horizontal and vertical coordinate systems. GIS queries using an interpolated groundwater level raster layer determined the vadose zone depth at each test-hole location of the study area. The thickness of low-permeability materials within the vadose zone depth, like silt and clay, was calculated at each test-hole location, and then interpolated into the whole study area using the optimized variograph and kriging in GIS. This raster map resulting from geostatistical simulation was used to characterize the vadose zone for the aquifer susceptibility modeling. Different from the traditional qualitative approach, this one captures both horizontal spatial variability and vertical structure of the vadose zone regarding its pollution prevention properties. The results showed that the Lower Elkhorn River Basin has a thick (averages about 14 feet) low-permeability vadose zone generally associated with low pollutant-leaching potential

  11. Monitoring Drought at Continental Scales Using Thermal Remote Sensing of Evapotranspiration (Invited)

    NASA Astrophysics Data System (ADS)

    Anderson, M. C.; Hain, C.; Mecikalski, J. R.; Kustas, W. P.

    2009-12-01

    assessing standard meteorologically-based drought indicators, and may be more robust in regions with limited monitoring networks. In this study, monthly maps of ESI anomalies for 2000-2008 are compared to standard drought indices and to drought classifications in the U.S. Drought Monitor. The ESI shows better skill in ranking drought severity than do precipitation-based indices composited over comparable time intervals. The thermal remote sensing inputs to ALEXI detect drought conditions even under the dense forest cover along the East Coast of the United States, where microwave soil moisture retrievals typically lose sensitivity. On the other hand, microwave observations are not constrained by cloud cover and provide better temporal continuity, but typically at significantly lower spatial resolution. A merged TIR-microwave moisture anomaly product may have potential for optimizing both spatial and temporal coverage in continental-scale drought monitoring.

  12. Prevalence of human rotavirus genotypes in Wuhan, China, during 2008-2011: changing trend of predominant genotypes and emergence of strains with the P[8]b subtype of the VP4 gene.

    PubMed

    Wang, Yuan-Hong; Zhou, Xuan; Ghosh, Souvik; Zhou, Dun-Jin; Pang, Bei-Bei; Peng, Jin-Song; Hu, Quan; Kobayashi, Nobumichi

    2011-12-01

    Hospital-based surveillance of rotavirus genotypes was conducted in Wuhan, China, between March 2008 and May 2011. The detection rates of group A rotavirus were 24.6% (458/1859) and 12.1% (96/795) in children and adults, respectively, with diarrhea. Among the 554 positive specimens, the most frequent genotype was G3P[8] (57.9%), followed by G1P[8] (29.4%). Compared with previous studies in Wuhan (2000-2008), the relative frequency of G3P[8] has been decreasing year by year, while the predominant genotype G3 shifted to G1 in 2011. In the present study, a rare P[8]b subtype of the VP4 gene (OP354-like P[8]) was identified in nine strains. Full-length sequences of VP7, VP4, VP6 and NSP4 genes of two G9P[8]b strains (RVA/Human-wt/CHN/E1545/2009/G9P[8]b and RVA/Human-wt/CHN/Z1108/2008/G9P[8]b) were determined for phylogenetic analysis. The four genes of these strains were closely related to one another, and the G9-VP7 genes of these strains belonged to lineage III, which contains globally spreading G9 rotaviruses. The full-length sequence of VP4 gene segments of the P[8]b strains in Wuhan clustered with those of P[8]b strains in Vietnam, Russia and Belgium, while they were distinct from those of the OP354 strain from Malawi and Bangladeshi strains. The VP6 and NSP4 genes of two P[8]b strains belonged to the I1 and E1 genotype, respectively, and clustered with those of strains belonging to Wa-like human rotaviruses from various Asian countries. These findings indicate the changing epidemiologic trend of rotavirus genotypes in Wuhan, i.e., the shift of the predominant type from G3 to G1 and the emergence of P[8]b strains genetically related to those distributed in other Asian countries.

  13. Effect of weight, height and BMI on injury outcome in side impact crashes without airbag deployment.

    PubMed

    Pal, Chinmoy; Tomosaburo, Okabe; Vimalathithan, K; Jeyabharath, M; Muthukumar, M; Satheesh, N; Narahari, S

    2014-11-01

    A comprehensive analysis is performed to evaluate the effect of weight, height and body mass index (BMI) of occupants on side impact injuries at different body regions. The accident dataset for this study is based on the National Automotive Sampling System-Crashworthiness Data System (NASS-CDS) for accident year 2000-08. The mean BMI values for driver and front passenger are estimated from all types of crashes using NASS database, which clearly indicates that mean BMI has been increasing over the years in the USA. To study the effect of BMI in side impact injuries, BMI was split into three groups namely (1) thin (BMI<21), (2) normal (BMI 24-27), (3) obese (BMI>30). For more clear identification of the effect of BMI in side impact injuries, a minimum gap of three BMI is set in between each adjacent BMI groups. Car model years from MY1995-1999 to MY2000-2008 are chosen in order to identify the degree of influence of older and newer generation of cars in side impact injuries. Impact locations particularly side-front (F), side-center (P) and side-distributed (Y) are chosen for this analysis. Direction of force (DOF) considered for both near side and far side occupants are 8 o'clock, 9 o'clock, 10 o'clock and 2 o'clock, 3 o'clock and 4 o'clock respectively. Age <60 years is also one of the constraints imposed on data selection to minimize the effect of bone strength on the occurrence of occupant injuries. AIS2+ and AIS3+ injury risk in all body regions have been plotted for the selected three BMI groups of occupant, delta-V 0-60kmph, two sets (old and new) of car model years. The analysis is carried with three approaches: (a) injury risk percentage based on simple graphical method with respect to a single variable, (b) injury distribution method where the injuries are marked on the respective anatomical locations and (c) logistic regression, a statistical method, considers all the related variables together. Lower extremity injury risk appears to be high for thin BMI

  14. Understanding Storm Time Poynting Flux Variability

    NASA Astrophysics Data System (ADS)

    Garner, H. M.; Ober, D. M.; Wilson, G. R.

    2012-12-01

    It is known that energy deposited by dayside Earth-directed Poynting flux (S||) is greater during geomagnetic storms; however, S|| spatial and temporal variability are less well understood. Eight years (2000-2008) of data from the WDC for Geomagnetism, Kyoto, were collected to identify thirteen large and five super storms according to specific criteria: "classic" storm structure in which the time interval between sudden storm commencement (SSC) and minimum Dst (Dstmin) was ≤ 24 hours; the main and recovery phases did not experience secondary or tertiary disturbances; large storms where Dst ≤ -93 nT; and, super storms where Dst ≤ -184 nT. Solar wind and magnetospheric data for the 18 storms were collected from the Defense Meteorological Satellite Program (DMSP F-15) and NASA OMNI. For all storms, the data were averaged and plotted to identify S|| variability for the mantle, cusp, polar rain, and central and boundary layer plasma sheet regions during geomagnetic storm time. As known for all storms, while Dst decreased, average S|| peaked, as did Kp. The energy deposited per square-meter by precipitating energetic particles (electrons) did not increase, though average hemispheric power increased by nearly a factor of two for the large and super storms between SSC and Dstmin. For the large storms, average S|| from the central and boundary layer plasma sheet regions (on closed field lines) was enhanced by nearly a factor of two between SSC and Dstmin; for the super storms, enhancement was over a factor of three. Average large storm S|| enhancement from the mantle, cusp, and polar rain regions (on open field lines) was significantly more enhanced by a factor of three between SSC and Dstmin. It was enhanced by a factor of over five for the super storms. For the open field line regions, a large, prolonged secondary peak in S|| was observed for large and super storms during the recovery phase. As suggested by this and prior studies, research is needed to better

  15. After accounting for competing causes of death and more advanced stage, do Aboriginal and Torres Strait Islander peoples with cancer still have worse survival? A population-based cohort study in New South Wales.

    PubMed

    Tervonen, Hanna E; Walton, Richard; You, Hui; Baker, Deborah; Roder, David; Currow, David; Aranda, Sanchia

    2017-06-02

    Aboriginal and Torres Strait Islander peoples in Australia have been found to have poorer cancer survival than non-Aboriginal people. However, use of conventional relative survival analyses is limited due to a lack of life tables. This cohort study examined whether poorer survival persist after accounting for competing risks of death from other causes and disparities in cancer stage at diagnosis, for all cancers collectively and by cancer site. People diagnosed in 2000-2008 were extracted from the population-based New South Wales Cancer Registry. Aboriginal status was multiply imputed for people with missing information (12.9%). Logistic regression models were used to compute odds ratios (ORs) with 95% confidence intervals (CIs) for 'advanced stage' at diagnosis (separately for distant and distant/regional stage). Survival was examined using competing risk regression to compute subhazard ratios (SHRs) with 95%CIs. Of the 301,356 cases, 2517 (0.84%) identified as Aboriginal (0.94% after imputation). After adjusting for age, sex, year of diagnosis, socio-economic status, remoteness, and cancer site Aboriginal peoples were more likely to be diagnosed with distant (OR 1.30, 95%CI 1.17-1.44) or distant/regional stage (OR 1.29, 95%CI 1.18-1.40) for all cancers collectively. This applied to cancers of the female breast, uterus, prostate, kidney, others (those not included in other categories) and cervix (when analyses were restricted to cases with known stages/known Aboriginal status). Aboriginal peoples had a higher hazard of death than non-Aboriginal people after accounting for competing risks from other causes of death, socio-demographic factors, stage and cancer site (SHR 1.40, 95%CI 1.31-1.50 for all cancers collectively). Consistent results applied to colorectal, lung, breast, prostate and other cancers. Aboriginal peoples with cancer have an elevated hazard of cancer death compared with non-Aboriginal people, after accounting for more advanced stage and competing

  16. Incorporating local land use regression and satellite aerosol optical depth in a hybrid model of spatiotemporal PM2.5 exposures in the Mid-Atlantic states.

    PubMed

    Kloog, Itai; Nordio, Francesco; Coull, Brent A; Schwartz, Joel

    2012-11-06

    Satellite-derived aerosol optical depth (AOD) measurements have the potential to provide spatiotemporally resolved predictions of both long and short-term exposures, but previous studies have generally shown moderate predictive power and lacked detailed high spatio- temporal resolution predictions across large domains. We aimed at extending our previous work by validating our model in another region with different geographical and metrological characteristics, and incorporating fine scale land use regression and nonrandom missingness to better predict PM(2.5) concentrations for days with or without satellite AOD measures. We start by calibrating AOD data for 2000-2008 across the Mid-Atlantic. We used mixed models regressing PM(2.5) measurements against day-specific random intercepts, and fixed and random AOD and temperature slopes. We used inverse probability weighting to account for nonrandom missingness of AOD, nested regions within days to capture spatial variation in the daily calibration, and introduced a penalization method that reduces the dimensionality of the large number of spatial and temporal predictors without selecting different predictors in different locations. We then take advantage of the association between grid-cell specific AOD values and PM(2.5) monitoring data, together with associations between AOD values in neighboring grid cells to develop grid cell predictions when AOD is missing. Finally to get local predictions (at the resolution of 50 m), we regressed the residuals from the predictions for each monitor from these previous steps against the local land use variables specific for each monitor. "Out-of-sample" 10-fold cross-validation was used to quantify the accuracy of our predictions at each step. For all days without AOD values, model performance was excellent (mean "out-of-sample" R(2) = 0.81, year-to-year variation 0.79-0.84). Upon removal of outliers in the PM(2.5) monitoring data, the results of the cross validation procedure was

  17. PM10 concentration levels at an urban and background site in Cyprus: the impact of urban sources and dust storms.

    PubMed

    Achilleos, Souzana; Evans, John S; Yiallouros, Panayiotis K; Kleanthous, Savvas; Schwartz, Joel; Koutrakis, Petros

    2014-12-01

    Air quality in Cyprus is influenced by both local and transported pollution, including desert dust storms. We examined PM10 concentration data collected in Nicosia (urban representative) from April 1, 1993, through December 11, 2008, and in Ayia Marina (rural background representative) from January 1, 1999, through December 31, 2008. Measurements were conducted using a Tapered Element Oscillating Micro-balance (TEOM). PM10 concentrations, meteorological records, and satellite data were used to identify dust storm days. We investigated long-term trends using a Generalized Additive Model (GAM) after controlling for day of week, month, temperature, wind speed, and relative humidity. In Nicosia, annual PM10 concentrations ranged from 50.4 to 63.8 μg/m3 and exceeded the EU annual standard limit enacted in 2005 of 40 μg/m3 every year A large, statistically significant impact of urban sources (defined as the difference between urban and background levels) was seen in Nicosia over the period 2000-2008, and was highest during traffic hours, weekdays, cold months, and low wind conditions. Our estimate of the mean (standard error) contribution of urban sources to the daily ambient PM10 was 24.0 (0.4) μg/m3. The study of yearly trends showed that PM10 levels in Nicosia decreased from 59.4 μg/m3 in 1993 to 49.0 μg/m3 in 2008, probably in part as a result of traffic emission control policies in Cyprus. In Ayia Marina, annual concentrations ranged from 27.3 to 35.6 μg/m3, and no obvious time trends were observed. The levels measured at the Cyprus background site are comparable to background concentrations reported in other Eastern Mediterranean countries. Average daily PM10 concentrations during desert dust storms were around 100 μg/m3 since 2000 and much higher in earlier years. Despite the large impact ofdust storms and their increasing frequency over time, dust storms were responsible for a small fraction of the exceedances of the daily PM10 limit. Implications: This

  18. Cumulative incidence of cancer after solid organ transplantation.

    PubMed

    Hall, Erin C; Pfeiffer, Ruth M; Segev, Dorry L; Engels, Eric A

    2013-06-15

    Solid organ transplantation recipients have elevated cancer incidence. Estimates of absolute cancer risk after transplantation can inform prevention and screening. The Transplant Cancer Match Study links the US transplantation registry with 14 state/regional cancer registries. The authors used nonparametric competing risk methods to estimate the cumulative incidence of cancer after transplantation for 2 periods (1987-1999 and 2000-2008). For recipients from 2000 to 2008, the 5-year cumulative incidence, stratified by organ, sex, and age at transplantation, was estimated for 6 preventable or screen-detectable cancers. For comparison, the 5-year cumulative incidence was calculated for the same cancers in the general population at representative ages using Surveillance, Epidemiology, and End Results data. Among 164,156 recipients, 8520 incident cancers were identified. The absolute cancer risk was slightly higher for recipients during the period from 2000 to 2008 than during the period from 1987 to 1999 (5-year cumulative incidence: 4.4% vs. 4.2%; P = .006); this difference arose from the decreasing risk of competing events (5-year cumulative incidence of death, graft failure, or retransplantation: 26.6% vs. 31.9%; P < .001). From 2000 to 2008, the 5-year cumulative incidence of non-Hodgkin lymphoma was highest at extremes of age, especially in thoracic organ recipients (ages 0-34 years: range, 1.74%-3.28%; aged >50 years; range, 0.36%-2.22%). For recipients aged >50 years, the 5-year cumulative incidence was higher for colorectal cancer (range, 0.33%-1.94%) than for the general population at the recommended screening age (aged 50 years: range, 0.25%-0.33%). For recipients aged >50 years, the 5-year cumulative incidence was high for lung cancer among thoracic organ recipients (range, 1.16%-3.87%) and for kidney cancer among kidney recipients (range, 0.53%-0.84%). The 5-year cumulative incidence for prostate cancer and breast cancer was similar or lower in

  19. Household exposure to violence and human rights violations in western Bangladesh (II): history of torture and other traumatic experience of violence and functional assessment of victims

    PubMed Central

    2009-01-01

    Background Organised crime and political violence (OPV) and human rights violations have marred Bangladesh history since 1971. Little is known about the consequences for the oppressed population. This study describes the patterns of OPV and human rights violations in a disturbed area of Bangladesh and assesses the physical, emotional and social functioning of victims. Methods A total of 236 of selected participants in a household survey in Meherpur district were recruited for a detailed study. Interviews and physical examinations were used to obtain information about history of torture and other cruel, inhuman or degrading treatment or punishment (TCIDTP), and about injuries, pain frequency and intensity. Handgrip strength and standing balance performance were measured. The "WHO-5 Well-being" scale was used to assess the subjective emotional well-being of study participants. Results The majority of the reported cases of TCIDTP occurred in 2000-2008, 51% of incidents occurred during winter; 32.0% between 20:00 and midnight. Police involvement was reported in 75% of cases. Incidents took place at victims' homes (46.7%), or at the police station, military camp, in custody or in prison (21.9%). Participants experienced 1-10 TCIDTP methods and reported 0-6 injury locations on their bodies; 77.5% reported having at least two injuries. Less than half of the participants were able to stand on one leg for 30 seconds. Only 7.5% of males aged 25-44 had handgrip strength in both hands exceeding average values for healthy people at the same age. Over 85% of participants scored low (<13) on the 25-point "WHO-5 Well-being" scale. The number of years since the TCIDTP event, pain frequency, the need to quit a job to take care of an injured family member, political involvement, personal conflicts and the fear of neighbourhood violence strongly affected emotional well-being. Good emotional well-being correlated with increased political and social participation. Conclusion A detailed

  20. Volumes of sediment stored in an Alpine catchment using geological, geomorphological and geophysical expertise: Peynin catchment (Queyras, Southern French Alps)

    NASA Astrophysics Data System (ADS)

    Carlier, Benoît; Carlier, Gabriel; Lissak, Candide; Gance, Julien; Malet, Jean-Philippe; Graff, Kevin; Viel, Vincent; Arnaud-Fassetta, Gilles; Fort, Monique; Bétard, François; Madelin, Malika

    2017-04-01

    The combination of predisposing factors (schist bedrock supplying abundant debris, high slope gradient and strong hillslope-channel connectivity), makes the Upper Guil catchment particularly prone to torrential hazards such as floods or debris flows. The occurrence of "Lombarde easterlies" episodes may generate intense rainfall over short time periods (320 mm in 8 days in June 1957). During such events, the observed damages are mainly related to the sediment transport (fine sediments and metric boulders) in the torrential streams, as in 1946 and 1957, and more recently in 2000, 2008 and 2010. In order to evaluate mountainous hazards in a Global Change context (i.e. climatic and socio-economic), the French funded ANR project SAMCO put the emphasis on the hydrogeomorphological functioning of the Upper Guil catchment. In this context, a sedimentary budget analysis at the Holocene timescale was elaborated for the active Peynin catchment (≈ 15 km2). The volumes of sediments stored on the slopes and in the channels are evaluated using geophysical and geomorphological investigations in order to establish the amount of material potentially mobilized during low frequency/high magnitude flood events. On the basis of intensive fieldwork and GIS mapping (geology and geomorphology), two models of sediment thickness are proposed. The first one, inspired by the work of Schrott et al. (2003), is based on the modelling of the supposed bedrock roof using polynomial functions and GIS modelling (high estimate). The second model is field based and results from a geological and geomorphological analysis of 46 topographic and geologic cross sections (low estimate). To reduce the error margins in sediment thickness estimates, three seismic refraction profiles made in summer 2014 have been interpreted and integrated to these models. The volumes of sediments stored in the Peynin catchment were respectively estimated to 0.423 km3 (high estimate) and 0.171 km3 (low estimate). This

  1. Trends in central nervous system tumor incidence relative to other common cancers in adults, adolescents, and children in the United States, 2000 to 2010

    PubMed Central

    Gittleman, Haley R; Ostrom, Quinn T; Rouse, Chaturia D; Dowling, Jacqueline A; de Blank, Peter M; Kruchko, Carol A; Elder, J Bradley; Rosenfeld, Steven S; Selman, Warren R; Sloan, Andrew E; Barnholtz-Sloan, Jill S

    2015-01-01

    BACKGROUND Time trends in cancer incidence rates (IR) are important to measure the changing burden of cancer on a population over time. The overall IR of cancer in the United States is declining. Although central nervous system tumors (CNST) are rare, they contribute disproportionately to mortality and morbidity. In this analysis, the authors examined trends in the incidence of the most common cancers and CNST between 2000 and 2010. METHODS The current analysis used data from the United States Cancer Statistics publication and the Central Brain Tumor Registry of the United States. Age-adjusted IR per 100,000 population with 95% confidence intervals and the annual percent change (APC) with 95% confidence intervals were calculated for selected common cancers and CNST overall and by age, sex, race/ethnicity, selected histologies, and malignancy status. RESULTS In adults, there were significant decreases in colon (2000-2010: APC, −3.1), breast (2000-2010: APC, −0.8), lung (2000-2010: APC, −1.1), and prostate (2000-2010: APC, −2.4) cancer as well as malignant CNST (2008-2010: APC, −3.1), but a significant increase was noted in nonmalignant CNST (2004-2010: APC, 2.7). In adolescents, there were significant increases in malignant CNST (2000-2008: APC, 1.0) and nonmalignant CNST (2004-2010: APC, 3.9). In children, there were significant increases in acute lymphocytic leukemia (2000-2010: APC, 1.0), non-Hodgkin lymphoma (2000-2010: APC, 0.6), and malignant CNST (2000-2010: APC, 0.6). CONCLUSIONS Surveillance of IR trends is an important way to measure the changing public health and economic burden of cancer. In the current study, there were significant decreases noted in the incidence of adult cancer, whereas adolescent and childhood cancer IR were either stable or increasing. Cancer 2015;121:102–112. © 2014 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. Time trends in cancer incidence rates are important to

  2. [Prevalence and associated risk factors of arterial hypertension in Sobremonte and Ojo de Agua Departments in Cordoba State].

    PubMed

    Pedraza, Antonio; Camino Willhuber, Gastón; Chaile, Iván

    2008-01-01

    Arterial Hypertension (AH) is a disease with multiple risk factors (RF), and it is one of the most important risk factor for cardiovascular diseases. The objective of this study was to determine the prevalence of AH in Sobremonte area and its correlation to other risk factors. The study was done in an special programme called "Solidarity in Health" (SIH) supported by the College of Medicine at the National University of Córdoba, which provided primary care to residents of Cachi Yaco (Sobremonte Department). It is an small village near Santiago del Estero province located in 226 km from Córdoba city. They went to the city and they examined the patients at the the "French and Berutti" school for nine consecutive years (2000-2008). Sobremonte area is the poorest deparment in the province of Córdoba and it has the highest rate of lowest socio-economic development, and a very deficient health care system.. The only hospital providing primary care is in San Francisco del Chañar, and the access is not free. The study involved the determination of the arterial pressure (AP) according to the seventh "JNC"criteria, body mass index (BMI), levels of alcohol consumption, exercise, salt consumption, diabetes and smoking in all the patients. Additionally, three water samples from different representative zones were collected and tested for sodium concentration. 471 patients were included. The incidence of AH was 43.5% of the patients. (51% men and 36% women). Higher incidence of AH was found in patients between 50 and 59 years old. There was a stadistical difference in the BMI, diabetes, and alcohol consumption between healthy patients and patients with AH. There was not any correlation between AH and exercise. We found higher levels of sodium in the water of this area and it was between 13-35 higher than in C6rdoba city and it was correlated with AH. We conclude that the increased sodium consumption is one of the most important risk factor of AH in this population.

  3. Adherence: a review of education, research, practice and policy in Australia

    PubMed Central

    Aslani, Parisa; Krass, Ines

    2008-01-01

    Community pharmacists are well placed to deliver adherence support services as well as other pharmaceutical services to patients. They are often the last point of contact with patients collecting medicines in the healthcare chain, and they tend to be visited by patients on a regular basis to collect prescription medicines. They have the opportunity to reinforce information already received from other health practitioners, provide further information and monitor adherence to therapy. The past decade has seen an increase in focus on the importance of adherence to therapy, not only in the higher education sector, but also in government policy and community pharmacy practice. Adherence monitoring and promotion has not only become the foundation of courses taught in pharmacy schools, but has become an essential component of disease management and pharmaceutical services delivered by community pharmacists. Aims This article aims to describe the education, research, practice and policy in the area of adherence to therapy in Australia with a focus on community pharmacists. Methods A search of MEDLINE and International Pharmaceutical Abstracts as well as hand searches of the bibliographies of retrieved articles was conducted for the period 2000-2008. All pharmacy schools in Australia were also contacted to obtain information on the patient adherence to therapy content of their courses. Results Ten studies met the inclusion criteria. Only one study had a specific adherence focus, with the remainder including adherence support and monitoring as part of the overall interventions delivered by the community pharmacists. In the majority of cases the interventions resulted in an improvement in patients’ adherence to therapy. The research was supported by government and pharmacy professional organisation initiatives in the area of cognitive pharmaceutical services. All universities which responded delivered specific patient adherence courses. Conclusions Australian pharmacy

  4. Using new satellite based exposure methods to study the association between pregnancy PM₂.₅ exposure, premature birth and birth weight in Massachusetts.

    PubMed

    Kloog, Itai; Melly, Steven J; Ridgway, William L; Coull, Brent A; Schwartz, Joel

    2012-06-18

    Adverse birth outcomes such as low birth weight and premature birth have been previously linked with exposure to ambient air pollution. Most studies relied on a limited number of monitors in the region of interest, which can introduce exposure error or restrict the analysis to persons living near a monitor, which reduces sample size and generalizability and may create selection bias. We evaluated the relationship between premature birth and birth weight with exposure to ambient particulate matter (PM₂.₅) levels during pregnancy in Massachusetts for a 9-year period (2000-2008). Building on a novel method we developed for predicting daily PM₂.₅ at the spatial resolution of a 10x10 km grid across New-England, we estimated the average exposure during 30 and 90 days prior to birth as well as the full pregnancy period for each mother. We used linear and logistic mixed models to estimate the association between PM₂.₅ exposure and birth weight (among full term births) and PM₂.₅ exposure and preterm birth adjusting for infant sex, maternal age, maternal race, mean income, maternal education level, prenatal care, gestational age, maternal smoking, percent of open space near mothers residence, average traffic density and mothers health. Birth weight was negatively associated with PM₂.₅ across all tested periods. For example, a 10 μg/m³ increase of PM₂.₅ exposure during the entire pregnancy was significantly associated with a decrease of 13.80 g [95% confidence interval (CI) = -21.10, -6.05] in birth weight after controlling for other factors, including traffic exposure. The odds ratio for a premature birth was 1.06 (95% confidence interval (CI) = 1.01-1.13) for each 10 μg/m3 increase of PM₂.₅ exposure during the entire pregnancy period. The presented study suggests that exposure to PM₂.₅ during the last month of pregnancy contributes to risks for lower birth weight and preterm birth in infants.

  5. Long-term elevated atmospheric CO2 enhances forest productivity

    NASA Astrophysics Data System (ADS)

    Loecke, T. D.; Groffman, P. M.; Treseder, K. K.; LaDeau, S.

    2011-12-01

    Global atmospheric CO2 concentrations are increasing at historically unprecedented but ecologically gradual rates. The implications of this perturbation for carbon sequestration and feedback on global climate change are difficult to predict due in part to its gradual and largely uniform nature. We used long-term (>40 years) spatial gradients in atmospheric CO2 concentration, produced by spatially heterogeneous fossil fuel combustion along a rural to urban transect, to test the hypotheses that 1) rural to urban CO2 spatial gradients are useful analogs for gradual climate change and 2) higher atmospheric CO2 concentration promotes tree growth and C sequestration. Fossil fuel derived CO2 imparts a distinctive 14C isotopic signature on atmospheric CO2; as this CO2 is fixed into annual tree rings, a proxy for fossil fuel derived CO2 is preserved. Ten four-year tree ring segments were analyzed for α-cellulose 14C content by AMS from trees within 10 closed canopy forested sites in the Baltimore Maryland metropolitan area. Tree growth parameters were assessed by measuring the annual ring width change of 224 trees across the 10 sites. A hierarchical Bayesian model was constructed to determine the influence of CO2 concentration and other site and environmental factors on tree growth. Our proxy for historical CO2 concentrations indicates a detectable but diminishing spatial CO2 gradient across the rural to urban transect that ranged from a 5.6% gradient during the 1970s to a 1.4% gradient in recent years (2000-2008). This observation is consistent with urban deindustrialization and concurrent expansion of suburban development. As an analog for future atmospheric conditions, this spatial gradient is equivalent to a temporal gradient of ca. 15, 7.2, 9.8, 2.6 years of atmospheric CO2 rise during the past four decades. The CO2 spatial gradient had an overall positive effect on tree size adjusted ring width growth. Modeled air surface temperature differences among sites indicate

  6. A Statewide Nested Case-Control Study of Preterm Birth and Air Pollution by Source and Composition: California, 2001-2008.

    PubMed

    Laurent, Olivier; Hu, Jianlin; Li, Lianfa; Kleeman, Michael J; Bartell, Scott M; Cockburn, Myles; Escobedo, Loraine; Wu, Jun

    2016-09-01

    Preterm birth (PTB) has been associated with exposure to air pollution, but it is unclear whether effects might vary among air pollution sources and components. We studied the relationships between PTB and exposure to different components of air pollution, including gases and particulate matter (PM) by size fraction, chemical composition, and sources. Fine and ultrafine PM (respectively, PM2.5 and PM0.1) by source and composition were modeled across California over 2000-2008. Measured PM2.5, nitrogen dioxide, and ozone concentrations were spatially interpolated using empirical Bayesian kriging. Primary traffic emissions at fine scale were modeled using CALINE4 and traffic indices. Data on maternal characteristics, pregnancies, and birth outcomes were obtained from birth certificates. Associations between PTB (n = 442,314) and air pollution exposures defined according to the maternal residence at birth were examined using a nested matched case-control approach. Analyses were adjusted for maternal age, race/ethnicity, education and neighborhood income. Adjusted odds ratios for PTB in association with interquartile range (IQR) increases in average exposure during pregnancy were 1.133 (95% CI: 1.118, 1.148) for total PM2.5, 1.096 (95% CI: 1.085, 1.108) for ozone, and 1.079 (95% CI: 1.065, 1.093) for nitrogen dioxide. For primary PM, the strongest associations per IQR by source were estimated for onroad gasoline (9-11% increase), followed by onroad diesel (6-8%) and commercial meat cooking (4-7%). For PM2.5 composition, the strongest positive associations per IQR were estimated for nitrate, ammonium, and secondary organic aerosols (11-14%), followed by elemental and organic carbon (2-4%). Associations with local traffic emissions were positive only when analyses were restricted to births with residences geocoded at the tax parcel level. In our statewide nested case-control study population, exposures to both primary and secondary pollutants were associated with an

  7. The effects of household income distribution on stroke prevalence and its risk factors of high blood pressure and smoking: a cross-sectional study in Saskatchewan, Canada.

    PubMed

    Bird, Yelena; Lemstra, Mark; Rogers, Marla

    2017-03-01

    Stroke is a major chronic disease and a common cause of adult disability and mortality. Although there are many known risk factors for stroke, lower income is not one that is often discussed. To determine the unadjusted and adjusted association of income distribution on the prevalence of stroke in Saskatchewan, Canada. Information was collected from the Canadian Community Health Survey conducted by Statistics Canada for 2000-2008. In total, 178 variables were analysed for their association with stroke. Prior to statistical adjustment, stroke was seven times more common for lower income residents than higher income residents. After statistical adjustment, only four covariates were independently associated with stroke prevalence, including having high blood pressure (odds ratio (OR) = 2.62; 95% confidence interval (CI) = 2.12-3.24), having a household income below CAD$30,000 per year (OR = 2.49; 95% CI = 1.88-3.29), being a daily smoker (OR = 1.36; 95% CI = 1.16-1.58) and being physically inactive (OR = 1.27; 95% CI = 1.13-1.43). After statistical adjustment, there were five covariates independently associated with high blood pressure prevalence, including having a household income below CAD$30,000 per year (OR = 1.52; 95% CI = 1.41-1.63). After statistical adjustment, there were five covariates independently associated with daily smoking prevalence, including having a household income below CAD$30,000 per year (OR = 1.29; 95% CI = 1.25-1.33). Knowledge of disparities in the prevalence, severity, disability and mortality of stroke is critically important to medical and public health professionals. Our study found that income distribution was strongly associated with stroke, its main disease intermediary - high blood pressure - and its main risk factor - smoking. As such, income is an important variable worthy of public debate as a modifiable risk factor for stroke.

  8. Will the light truck bumper height-matching standard reduce deaths in cars?

    PubMed

    Ossiander, Eric M; Koepsell, Thomas D; McKnight, Barbara

    2013-03-01

    In a collision between a car and a sport utility vehicle (SUV) or pickup truck, car occupants are more likely to be killed than if they crashed with another car. Some of the excess risk may be due to the propensity of SUVs and pickups with high bumpers to override the lower bumpers in cars. To reduce this incompatibility, particularly in head-on collisions, in 2003 automobile manufacturers voluntarily established a bumper height-matching standard for pickups and SUVs. To assess whether height-matching bumpers in pickups and SUVs were associated with the risk of death in either car occupants or pickup and SUV occupants. Case-control study of collisions between one car and one SUV or pickup in the US during 2000-2008, in which the SUV or pickup was model year 2000-2006. Cases were all decedents in fatal crashes; one control was selected from each crash in a national probability sample of crashes. Occupants of cars that crashed with SUVs or pickups with height-matching bumpers may be at slightly reduced risk of death compared to those that crashed with other SUVs or pickups (adjusted odds ratio: 0.83 (95% confidence interval 0.61-1.13)). There was no evidence of a reduction in risk in head-on crashes (1.09 (0.66-1.79)). In crashes in which the SUV or pickup struck the car on the side, height-matched bumpers were associated with a reduced risk of death (0.68 (0.48-0.97)). Occupants of SUVs and pickups with height-matching bumpers may also be at slightly reduced risk of death (0.91 (0.64-1.28)). Height-matching bumpers were associated with a reduced risk of death among car occupants in crashes in which SUVs or pickups struck cars in the side, but there was little evidence of an effect in head-on crashes. The new bumper height-matching standard may not achieve its primary goal of reducing deaths in head-on crashes, but may modestly reduce overall deaths in crashes between cars and SUVs or pickups because of unanticipated benefits to car occupants in side crashes, and a

  9. Verification of Atmospheric Signals Associated with Major Seismicity by Space and Terrestrial Observations

    NASA Astrophysics Data System (ADS)

    Ouzounov, D.; Pulinets, S.; Taylor, P.; Bryant, N.; Cervone, G.; Kafatos, M.; Habib, S.

    2008-12-01

    Observations from the last twenty years suggest the existence of electromagnetic (EM) phenomena during or preceding some earthquakes [Hayakawa et al, 2004; Pulinets at al, 1999,2004, 2006, Ouzounov et al, 2007 and Liu et al, 2004]. Both our previous studies [Pulinets at al, 2005, 2006, Ouzounov et al, 2006, 2007] and the latest review by the Earthquake Remote Precursor Sensing panel [ERPS; 2003-2005]; have shown that there were precursory atmospheric TIR signals observed on the ground and in space associated with several recent earthquakes. [Tramutoli et al, 2005, 2006, Cervone et al, 2006, Ouzounov et al, 2004,2006]. To study these signals, we applied both multi parameter statistical analysis and data mining methods that require systematic measurements from an Integrated Sensor Web of observations of several physical and environmental parameters. These include long wave earth infra-red radiation, ionospheric electrical and magnetic parameters, temperature and humidity of the boundary layer, seismicity and may be associated with major earthquakes. Our goal is to verify the earthquake atmospheric correlation in two cases: (i) backward analysis - 2000-2008 hindcast monitoring of multi atmospheric parameters over the Kamchatka region, Russia ; and (ii) forward real-time alert analysis over different seismo-tectonic regions for California, Turkey, Taiwan and Japan. Our latest results, from several post-earthquake independent analyses of more then 100 major earthquakes, show that joint satellite and some ground measurements, using an integrated web, could provide a capability for observing pre-earthquake atmospheric signals by combining the information from multiple sensors into a common framework. Using our methodology, we evaluated and compared the observed signals preceding the latest M7.9 Sichuan earthquake (05/12/2008), M8.0 earthquake in Peru (08/15/2007), M7.6 Kashmir earthquake (10/08/2005) and M9.0 Sumatra earthquake (12/26/2004). We found evidence of the

  10. Prescription Drug Use and Polypharmacy Among Medicaid-Enrolled Adults with Autism: A Retrospective Cross-Sectional Analysis.

    PubMed

    Vohra, Rini; Madhavan, Suresh; Sambamoorthi, Usha; StPeter, Claire; Poe, Susannah; Dwibedi, Nilanjana; Ajmera, Mayank

    2016-12-01

    A lack of gold standard treatment for autism spectrum disorders (ASD), no clear ASD management guidelines, and lack of evidence-based pharmacological interventions other than aripiprazole and risperidone elevate the risk of off-label prescribing and adverse effects among individuals with ASD, more so among adults. The aim of this study was to identify and compare the types of prescription drug use, rates of polypharmacy, and characteristics associated with polypharmacy among adults with and without ASD in a retrospective cross-sectional analysis of a three-state Medicaid Analytic eXtract database (2000-2008). Adults aged 22-64 years with ASD (ICD9-CM code: 299.xx) were propensity score-matched to 'no ASD' controls by age, sex, and race. General polypharmacy (≥6 unique classes of prescription drugs in a year) and psychotropic polypharmacy (≥3 unique prescription drug classes of psychotropic medications within a 90-day period) were the main study outcomes. Chi-square tests for rates, t tests for mean number of claims, and multivariate logistic regressions for likelihood of prescription drug use and polypharmacy were run. Annually, almost 75% of adults with ASD had >20 prescription drug claims compared with 33% of adults without ASD. Around 85% of adults with ASD used at least one psychotropic drug class compared with 42% of adults without ASD. Highly common psychotropics were antipsychotics (66%ASD vs 20%noASD), anticonvulsants (59%ASD vs 20%noASD), and anxiolytics/hypnotics/sedatives (21%ASD vs 11%noASD). Other than psychotropics, many adults with ASD used medical prescription drugs such as antimicrobials (47%), dermatologic agents (48%), respiratory agents (38%), gastrointestinal agents (31%), alternative medications (25%), antiparkinsonian agents (22.6%), antihyperlipidemics/statins (7.3%), and immunologics (2.0%). Rates of general (48%ASD vs 32%noASD) and psychotropic polypharmacy (19%ASD vs 6%noASD) were significantly higher in the ASD group. Prescription

  11. Costs of hospital events in patients with metastatic colorectal cancer.

    PubMed

    Overbeek, Jetty A; Zhao, Zhongyun; van Herk-Sukel, Myrthe P P; Barber, Beth L; Gao, Sue; Herings, Ron M C

    2011-01-01

    In the last decade, the number of new agents, including monoclonal antibodies, being developed to treat metastatic colorectal cancer (mCRC) increased rapidly. While improving outcomes, these new treatments also have distinct and known safety profiles with toxicities that may require hospitalizations. However, patterns and costs of hospitalizations of toxicities of these new 'targeted' drugs are often unknown. This study aimed to estimate the costs of hospital events associated with adverse events specified in the 'Special Warnings and Precautions for Use' section of the European Medicinal Agency Summary of Product Characteristics for bevacizumab, cetuximab, and panitumumab, in patients with mCRC. From the PHARMO Record Linkage System (RLS), patients with a primary or secondary hospital discharge code for CRC and distant metastasis between 2000-2008 were selected and defined as patients with mCRC. The first discharge diagnosis defining metastases served as the index date. Patients were followed from index date until end of data collection, death, or end of study period, whichever occurred first. Hospital events during follow-up were identified through primary hospital discharge codes. Main outcomes for each event were length of stay and costs per hospital admission. Among 2964 mCRC patients, 271 hospital events occurred in 210 patients (mean [SD] duration of follow-up: 34 [31] months). The longest mean (SD) length of stay per hospital admission were for stroke (16 [33] days), arterial thromboembolism (ATE) (14 [21] days), wound-healing complications (WHC), acute myocardial infarction (AMI), congestive heart failure (CHF), and neutropenia (all 9 days; SD 5-15). Highest mean (SD) costs per admission were for stroke (€13,500 [€28,800]), ATE (€13,300 [€18,800]), WHC (€10,800 [€20,500]). Although no causal link could be identified between any specific event and any specific treatment, data from this study are valuable for pharmacoeconomic evaluations of newer

  12. Relationships between present/future climate and PM2.5 concentrations over Europe

    NASA Astrophysics Data System (ADS)

    Lecoeur, E.; Seigneur, C.; Page, C.; Terray, L.

    2012-12-01

    types, obtained by classifying the pressure at sea level, the precipitation, and the temperature. As these variables impact the PM2.5 concentrations, these weather types are build to be discriminatory for PM2.5 concentrations. We investigate the relationships between theses weather types and the PM2.5 concentrations for 2000-2008. By assuming that the weather types will remain the same in the future (stationarity), we use different model predictions provided by the IPCC to study how the frequency of the weather types will change in the future, and how this climate change will affect the PM2.5 concentrations.

  13. Remotely sensed forest phenology and its relation with Nephropathia

    NASA Astrophysics Data System (ADS)

    Barrios, J. M.

    2010-05-01

    J.M. Barrios1, W.W. Verstraeten1, P. Maes2, J. Clement2, J-M. Aerts1, S. Amirpour1, J. Wambacq2, K. Lagrou3, M. Van Ranst2, D. Berckmans1, P. Coppin1 1. Katholieke Universiteit Leuven, Biosystems Departement, M3-BIORES, Willem de Croylaan 34, B-3001 Leuven, Belgium 2. Katholieke Universiteit Leuven, Laboratory of Clinical Virology, Hantavirus Reference Center, Rega Institute, Minderbroedersstraat 10, B-3000 Leuven, Belgium 3. Katholieke Universiteit Leuven, Department of Experimental Laboratory Medicine, Herestraat 49, B-3000 Leuven, Belgium Nephropathia epidemica (NE), a mild form of haemorrhagic fever with renal syndrome, is a zoonotic disease caused by a Hanta virus called Puumala virus in Europe. Concern about this disease has increased in recent years due to the increase in the amount of reported cases. In 2005, 2007 and 2008 the number of infected cases surpassed 300 cases per 100000 inhabitants in Belgium, which was never observed before. NE incidence is closely related to environmental conditions. The main role in the virus transmission mechanism is played by the red bank vole (Myodes glareolus), a rodent species that is native in West European broad-leaved forests (BLF) and acts as the virus reservoir. Although the link between vegetation and NE in Belgium has been underlined repeatedly in recent research works, so far little has been done towards the exploration of remote sensing techniques for analyzing vegetation systems as an input in early warning systems. This study aims at determining whether observed NE occurrence pattern in Belgium can be connected to specific trends in BLF phenology parameters. Hence, phenology information was derived from time series of the MODIS Enhanced Vegetation Index (EVI) for the period 2000-2008 in 10 major BLF in southern Belgium. EVI values were calculated from the MOD09A1 dataset which provides an estimate of the surface spectral reflectance for bands 1-7 at 500 m resolution every 8 days. Based on our preliminary

  14. Earthquake statistics, spatiotemporal distribution of foci and source mechanisms - a key to understanding of the West Bohemia/Vogtland earthquake swarms

    NASA Astrophysics Data System (ADS)

    Horálek, Josef; Čermáková, Hana; Fischer, Tomáš

    2016-04-01

    Earthquake swarms are sequences of numerous events closely clustered in space and time and do not have a single dominant mainshock. A few of the largest events in a swarm reach similar magnitudes and usually occur throughout the course of the earthquake sequence. These attributes differentiate earthquake swarms from ordinary mainshock-aftershock sequences. Earthquake swarms occur worldwide, in diverse geological units. The swarms typically accompany volcanic activity at margins of the tectonic plate but also occur in intracontinental areas where strain from tectonic-plate movement is small. The origin of earthquake swarms is still unclear. The swarms typically occur at the plate margins but also in intracontinental areas. West Bohemia-Vogtland represents one of the most active intraplate earthquake-swarm areas in Europe. It is characterised by a frequent reoccurrence of ML < 4.0 swarms and by high activity of crustal fluids. West Bohemia-Vogtland is one of the most active intraplate earthquake-swarm areas in Europe which also exhibits high activity of crustal fluids. The Nový Kostel focal zone (NK) dominates the recent seismicity, there were swarms in 1997, 2000, 2008 and 20011, and a striking non-swarm activity (mainshock-aftershock sequences) up to magnitude ML= 4.5 in May to August 2014. The swarms and the 2014 mainshock-aftershock sequences are located close to each other at depths between 6 and 13 km. The frequency-magnitude distributions of all the swarms show bimodal-like character: the most events obey the b-value = 1.0 distribution, but a group of the largest events depart significantly from it. All the ML > 2.8 swarm events are located in a few dense clusters which implies step by step rupturing of one or a few asperities during the individual swarms. The source mechanism patters (moment-tensor description, MT) of the individual swarms indicate several families of the mechanisms, which fit well geometry of respective fault segments. MTs of the most

  15. The Cloud-Radiative Forcing of North American landfalling Atmospheric Rivers

    NASA Astrophysics Data System (ADS)

    Luo, Q.; Tung, W. W.

    2015-12-01

    Atmospheric Rivers (ARs) are narrow elongated regions with strong horizontal water vapor flux associated with extratropical cyclones. Upon making landfall, conspicuous mid-to-high-latitude stratiform cloud decks with high reflectivity are observed along with the ARs in satellite imagery. The cloud-radiative forcing (CRF) associated with these clouds has only been preliminarily established (e.g., Luo and Tung 2015). Their climatological impacts are not understood, yet the related cloud microphysics and radiation processes are poorly represented in global climate models. We studied the correlations between observed variables including the ECMWF-Interim horizontal water vapor fluxes (IVT) integrated from 1000—300 hPa, CERES-derived cloud water path and CRF, and MODIS cirrus reflectance before, during, and after the ARs impinged on the southwest and northwest coasts of North America (NA) in Nov—March, 2000-2008, with 60 ARs affecting the southwest coast (southwest ARs), and 60 ARs affecting the northwest coast (northwest ARs, Dettinger et al., 2011). Anomalies were calculated by subtracting the average over all time steps. For the southwest ARs, a significant increase of ice clouds took place around the landfalling regions with IVT anomalies >130 kg/m/s on landfalling day-1 and day+0. On day+1, a substantial increase of ice clouds with 50% reduction of IVT anomalies was found along with the ARs. On day+2 to day+3, positive IVT anomalies existed over the central and eastern US. These anomalies could be attributed to the southwest ARs and the secondary ARs that rooted in the Gulf of Mexico and made landfall over central and eastern US. Many parts of the NA continent were covered under ice cloud decks. The IVT anomalies for the northwest ARs were >250 kg/m/s on day-1 to day+0, and approximately 120 kg/m/s on day+1. Nevertheless, the northwest ARs were not observed to make landfall concurrently with the secondary landfalling ARs from the Gulf of Mexico. Only a small

  16. Significance of isolated hepatic veno-occlusive disease/sinusoidal obstruction syndrome after liver transplantation.

    PubMed

    Sebagh, Mylène; Azoulay, Daniel; Roche, Bruno; Hoti, Emir; Karam, Vincent; Teicher, Elina; Bonhomme-Faivre, Laurence; Saliba, Faouzi; Duclos-Vallée, Jean-Charles; Samuel, Didier

    2011-07-01

    After liver transplantation (LT), hepatic veno-occlusive disease (VOD), which is also known as sinusoidal obstruction syndrome (SOS), has been reported initially in relation to azathioprine use and subsequently in relation to acute rejection (AR). Isolated veno-occlusive disease (iVOD)/SOS raises some questions about its significance and especially its treatment. From the post-LT biopsy samples of 1364 patients (2000-2008), 31 patients with index biopsy samples showing VOD/SOS (2.3%) were identified. After a review of the index biopsy samples and previous biopsy samples, those patients not exposed to azathioprine therapy were subdivided into 2 groups according to the absence or presence of AR. Fifteen of the 31 patients had no previous evidence of AR, whereas 16 experienced episodes of AR (before or concurrently with VOD). The 2 groups were similar in terms of demographic and clinical data and the range of histological centrilobular changes. AR episodes were characterized by an endothelial predilection. iVOD/SOS occurred later than acute rejection-related veno-occlusive disease (AR-VOD)/SOS (mean times of 65 and 4.4 months, respectively, P = 0.0098). There was a tendency for iVOD/SOS to progress less frequently to chronic rejection in comparison with AR-VOD/SOS (3/15 versus 9/15, P = 0.06). The histological resolution of iVOD/SOS was significantly more frequent in patients who benefited from increased immunosuppression in comparison with those who did not (5/7 versus 2/8, P = 0.05). When the groups were considered together, the same result was obtained (14/18 versus 4/12, P = 0.024). In conclusion, despite a constant overall prevalence of VOD/SOS, the proportion of iVOD/SOS has increased. The histological resolution of iVOD/SOS after increase in immunosuppression suggests an immune-mediated origin. Better optimization of immunosuppression may be a curative treatment.

  17. Long-term particulate matter modeling for health effect studies in California - Part 2: Concentrations and sources of ultrafine organic aerosols

    NASA Astrophysics Data System (ADS)

    Hu, Jianlin; Jathar, Shantanu; Zhang, Hongliang; Ying, Qi; Chen, Shu-Hua; Cappa, Christopher D.; Kleeman, Michael J.

    2017-04-01

    Organic aerosol (OA) is a major constituent of ultrafine particulate matter (PM0. 1). Recent epidemiological studies have identified associations between PM0. 1 OA and premature mortality and low birth weight. In this study, the source-oriented UCD/CIT model was used to simulate the concentrations and sources of primary organic aerosols (POA) and secondary organic aerosols (SOA) in PM0. 1 in California for a 9-year (2000-2008) modeling period with 4 km horizontal resolution to provide more insights about PM0. 1 OA for health effect studies. As a related quality control, predicted monthly average concentrations of fine particulate matter (PM2. 5) total organic carbon at six major urban sites had mean fractional bias of -0.31 to 0.19 and mean fractional errors of 0.4 to 0.59. The predicted ratio of PM2. 5 SOA / OA was lower than estimates derived from chemical mass balance (CMB) calculations by a factor of 2-3, which suggests the potential effects of processes such as POA volatility, additional SOA formation mechanism, and missing sources. OA in PM0. 1, the focus size fraction of this study, is dominated by POA. Wood smoke is found to be the single biggest source of PM0. 1 OA in winter in California, while meat cooking, mobile emissions (gasoline and diesel engines), and other anthropogenic sources (mainly solvent usage and waste disposal) are the most important sources in summer. Biogenic emissions are predicted to be the largest PM0. 1 SOA source, followed by mobile sources and other anthropogenic sources, but these rankings are sensitive to the SOA model used in the calculation. Air pollution control programs aiming to reduce the PM0. 1 OA concentrations should consider controlling solvent usage, waste disposal, and mobile emissions in California, but these findings should be revisited after the latest science is incorporated into the SOA exposure calculations. The spatial distributions of SOA associated with different sources are not sensitive to the choice of

  18. Investigation of temporal and spatial climate variability and aridity of Iran

    NASA Astrophysics Data System (ADS)

    Ashraf, B.; Yazdani, R.; Mousavi-Baygi, M.; Bannayan, M.

    2014-10-01

    The aim of this research is to study the spatial and temporal variability of aridity in Iran, through analysis of temperature and precipitation trends during the 48-year period of 1961-2008. In this study, four different aridity criteria have been used to investigate the aridity situation. These aridity indexes included Lang's index or rain factor, Budyko index or radiational index of dryness, UNEP aridity index, and Thornthwaite moisture index. The results of the analysis indicated that the highest and lowest mean temperatures occurred in July and January respectively in all locations. Among the study locations, Ahvaz with 37.1 °C and Kermanshah with 20.2 °C has the highest and lowest in July. For January, the highest was 12.4 °C for Ahvaz and the lowest was -4.5 °C for Hamedan and Kermanshah together. The range of monthly mean temperature of study locations indicated that the maximum and minimum difference between day and night temperatures, almost in all study locations, occurred in September and January, respectively, and the highest and lowest fluctuation of temperature was observed in Kerman and Tehran. The temperature anomalies showed that the most significant increasing temperature occurred at the beginning of twenty-first century (2000-2008) in all locations. The long-term mean of monthly rainfall showed that, in most study locations, the maximum and minimum of mean precipitation occurred in winter and summer, respectively. Rasht with 1,355 mm had the highest and Yazd with 55 mm had the lowest of total precipitation compared with other locations. According to precipitation anomalies, all locations experienced dry and wet periods, but generally dry periods occurred more often especially in the beginning of twenty-first century. According to applied different aridity indexes, all the study locations often experienced semi-arid to arid climate, severe water deficit to desert climate, arid to hyperarid climate, and semi-arid climate during the study period.

  19. Net greenhouse gas balance in response to nitrogen enrichment: perspectives from a coupled biogeochemical model.

    PubMed

    Lu, Chaoqun; Tian, Hanqin

    2013-02-01

    Increasing reactive nitrogen (N) input has been recognized as one of the important factors influencing climate system through affecting the uptake and emission of greenhouse gases (GHG). However, the magnitude and spatiotemporal variations of N-induced GHG fluxes at regional and global scales remain far from certain. Here we selected China as an example, and used a coupled biogeochemical model in conjunction with spatially explicit data sets (including climate, atmospheric CO2 , O3 , N deposition, land use, and land cover changes, and N fertilizer application) to simulate the concurrent impacts of increasing atmospheric and fertilized N inputs on balance of three major GHGs (CO2 , CH4 , and N2 O). Our simulations showed that these two N enrichment sources in China decreased global warming potential (GWP) through stimulating CO2 sink and suppressing CH4 emission. However, direct N2 O emission was estimated to offset 39% of N-induced carbon (C) benefit, with a net GWP of three GHGs averaging -376.3 ± 146.4 Tg CO2  eq yr(-1) (the standard deviation is interannual variability of GWP) during 2000-2008. The chemical N fertilizer uses were estimated to increase GWP by 45.6 ± 34.3 Tg CO2  eq yr(-1) in the same period, and C sink was offset by 136%. The largest C sink offset ratio due to increasing N input was found in Southeast and Central mainland of China, where rapid industrial development and intensively managed crop system are located. Although exposed to the rapidly increasing N deposition, most of the natural vegetation covers were still showing decreasing GWP. However, due to extensive overuse of N fertilizer, China's cropland was found to show the least negative GWP, or even positive GWP in recent decade. From both scientific and policy perspectives, it is essential to incorporate multiple GHGs into a coupled biogeochemical framework for fully assessing N impacts on climate changes. © 2012 Blackwell Publishing Ltd.

  20. Rapid Fire Damage Assessment by Using a Synergic Approach with Radar and Optical Data

    NASA Astrophysics Data System (ADS)

    Cadau, Enrico G.; Burini, Alessandro; Putignano, Cosimo; Goryl, Philippe; Gascon, Ferran; Miranda, Nuno; Laur, Henri

    2010-12-01

    Forest fires represent the main cause of forest degradation in the Mediterranean area. This phenomenon, progressively increasing, reached an average of 57,000 fires per year in the period 2000-2008 with the destruction of almost 450,000 ha of vegetated areas in southern European countries. Fires occurring in the Mediterranean area are rarely significant in terms of pollution or greenhouse gases released to the atmosphere. Nevertheless, they have a dramatic impact on forest and scrub in regions with relatively sparse vegetation, as well as on human lives and infrastructures. The most effective passive remote- sensing methods for detecting and mapping burn scars in vegetated areas, rely upon the observation of near- infrared (NIR) and short-wavelength infrared (SWIR) bands, with wavelengths comprised between 0.8 and 2.3μm. An innovative method to separate reflectance variation due to vegetation damages from changes due to other factors influencing the at-satellite reflectance is that of identifying pseudo-invariant features to be used as reference targets in different scenes. On the other hand, SAR seems to be another good candidate for fire assessment, because of sensitivity of backscattering to the geometric structure of targets and surfaces, particularly during the fire, when the smoke makes the approach with optical sensors not feasible. The incident wave is influenced by several target's parameters, such as moisture, orientation, roughness. When a fire occurs, the landscape is modified dramatically; the grassland, the leaves and bushes are completely burned, while the trunks can disappear depending on the fire intensity. The backscattering of a vegetated area is mainly dominated by a volumetric scattering mechanism, with the backscattered wave is highly depolarized; after a fire, when all the vegetation has been burnt, the backscattering is dominated by a surface scattering mechanism (burnt soil) or by the double bounce mechanism (by the presence of scattered

  1. Parametric Reconstruction of Water Vapour Accumulation Modes in the Western and the Eastern Mediterranean Basins

    NASA Astrophysics Data System (ADS)

    Palau, J. L.; Rovira, F.; Millan, M.

    2009-09-01

    The Mediterranean Sea acts as a source of heat and moisture for the surrounding regions, but not only because it is a closed and warm sea. The Mediterranean Basin is located in the mid-latitudes (i.e., high solar insolation), and it is almost completely surrounded by mountains. Moreover, from a meteorological point of view, the Mediterranean Basin can be regarded as two well-differentiated sub-basins: The Western Mediterranean Basin, where the prevailing synoptic conditions are associated with the Azores High Pressure system; and the Eastern Mediterranean Basin, which is under the influence of the Middle-East monsoon low-pressure system. The combination of all these features enables strong evapotranspiration with lower ventilation conditions (especially on the Western side) than in other geographical areas of the world (e.g., areas under the direct influence of the Atlantic Ocean). As a result, there are different water vapour "accumulation modes” on both sides of the Mediterranean Basin. The determination of the main atmospheric accumulation modes and their seasonal variability on both sides of the Mediterranean Basin is a relevant issue for integrating some of the feedbacks driving climate change, e.g., precipitation regimes, secondary pollutant production, ventilation conditions, etc. This study focuses on the total water vapour accumulation modes found on both sides of the Mediterranean Basin throughout the year. The data used in this study come from the most recent EOS satellite missions. Specifically, this investigation analyses the nine-year time series of water vapour data measured by the MODIS instrument (MODerate Resolution Imaging Spectroradiometer) on board the TERRA (EOS AM-1) satellite. Annual evolution (2000-2008) and seasonality of the total precipitable water column are analysed in both the Western and the Eastern Mediterranean Basins. After carrying out the parametric reconstruction of the water vapour time series, we have obtained their

  2. A Long Term View of Forest Response to Environmental Change: 25 Years of Studying Harvard Forest

    NASA Astrophysics Data System (ADS)

    Munger, J. W.; Wofsy, S. C.; Lindaas, J.; David, F.; David, O.

    2014-12-01

    Forests influence the budgets of greenhouse gases, and understanding how they will respond to environmental change is critical to accurately predicting future GHG trends. The time scale for climate change is long and forest growth is slow, thus very long measurement periods are required to observe meaningful forest response. We established an eddy flux tower within a mixed forest stand dominated by red oak and red maple at the Harvard Forest LTER site in 1989 where CO2, H2O and energy fluxes together with meteorological observations have been measured continuously. An array of plots for biometric measurements was established in 1993. Flux measurement at an adjacent hemlock stand began in 2000. Records of land use and disturbance and vegetation plot data extend back to 1907. The combined suite of measurements merges observations of instantaneous ecosystem responses to environmental forcing with details of vegetation dynamics and forest growth that represent the emergent properties relevant to long-term ecosystem change. Both the deciduous stand and hemlock stand are accumulating biomass. Each has added over 20 Mg-C ha-1 as woody biomass in trees >10cm dbh since 1990, even though the hemlock stand is older. Net carbon exchange shows enhanced uptake in early spring and late fall months in response to warmer temperatures and likely an increase in evergreen foliage at the deciduous site. Net carbon uptake efficiency at the deciduous stand has increased over time as well as indicated by peak NEE under optimum light conditions. The trend is only partly explained by variation in mean leaf area index and cannot be directly attributed to climate response. The combination of longer growing season and increased uptake efficiency yields a general trend of increasing annual NEE (Fig. 1). However, significant excursions in the trend highlight the sensitivity of forest carbon stocks. The pulse of high annual carbon uptake (peak 6 Mg-C ha-1y-1 in 2008) from 2000-2008 is only

  3. Long GPS coordinate time series: multipath and geometry effects

    NASA Astrophysics Data System (ADS)

    King, M. A.; Watson, C. S.

    2009-04-01

    Within analyses of Global Positioning System (GPS) observations, unmodelled sub-daily signals are known to propagate into long-period signals via a number of different mechanisms. In this paper, we investigate the effects of time-variable satellite geometry and the propagation of an unmodelled multipath signal that is analogous to a change in the elevation dependant phase centre of the receiving antenna. Multipath reflectors at H=0.1 m, 0.2 m and 1.5 m below the antenna are modeled and their effects on GPS coordinate time series are examined. Simulated time series at 20 global IGS sites for 2000-2008 were derived using the satellite geometry as defined by daily broadcast orbits, in addition to that defined using a perfectly repeating synthetic orbit. For the simulations generated using the broadcast orbits with a perfectly clear horizon, we observe the introduction of a time variable bias in the time series of up to several centimeters. Considerable site to site variability of the frequency and magnitude of the signal is observed, in addition to variation as a function of multipath source. When adopting realistic GPS observation geometries obtained from real data (e.g., those that include the effects of tracking outages, local obstructions, etc.), we observe concerning levels of temporal coordinate variation in the presence of the multipath signals. In these cases, we observe spurious signals across the frequency domain, in addition to what appears as offsets and secular trends. Velocity biases of more than 1mm/yr are evident at some few sites. The propagated signal in the vertical component is consistent with a noise model with a spectral index marginally above flicker noise (mean index -1.4), with some sites exhibiting power law magnitudes at comparable levels to actual height time series generated in GIPSY. The propagated signal also shows clear spectral peaks across all coordinate components at harmonics of the draconitic year for a GPS satellite (351.4 days

  4. Long GPS coordinate time series: multipath and geometry effects

    NASA Astrophysics Data System (ADS)

    King, M.; Watson, C. S.

    2009-12-01

    Within analyses of Global Positioning System (GPS) observations, unmodelled sub-daily signals are known to propagate into long-period signals via a number of different mechanisms. We report on the effects of time-variable satellite geometry and the propagation of an unmodelled multipath signal. Multipath reflectors at H=0.1 m, 0.2 m and 1.5 m below the antenna are modeled and their effects on GPS coordinate time series are examined. Simulated time series at 20 global IGS sites for 2000-2008 were derived using the satellite geometry as defined by daily broadcast orbits, in addition to that defined using a perfectly repeating synthetic orbit. For the simulations generated using the broadcast orbits with a perfectly clear horizon, we observe the introduction of a time variable bias in the time series of up to several centimeters. Considerable site to site variability of the frequency and magnitude of the signal is observed, in addition to variation as a function of multipath source. When adopting realistic GPS observation geometries obtained from real data (e.g., those that include the effects of tracking outages, local obstructions, etc.), we observe concerning levels of temporal coordinate variation in the presence of the multipath signals. In these cases, we observe spurious signals across the frequency domain, in addition to what appears as offsets and secular trends. Velocity biases of more than 1mm/yr are evident at some few sites. The propagated signal in the vertical component is consistent with a noise model with a spectral index marginally above flicker noise (mean index -1.4), with some sites exhibiting power law magnitudes at comparable levels to actual height time series generated in GIPSY. The propagated signal also shows clear spectral peaks across all coordinate components at harmonics of the draconitic year for a GPS satellite (351.2 days). When a perfectly repeating synthetic GPS constellation is used, the simulations show near-negligible power law

  5. Assessment of Groundwater Vulnerability by the Future Land Use Change in Geum River Watershed

    NASA Astrophysics Data System (ADS)

    Cheong, B.; Ko, K.; Ha, K.; Koh, D.

    2011-12-01

    determined as optimum model by logistic regression in Geum river watershed. The logistic regression method was also applied to predict groundwater vulnerability reflecting the future change of land use of Geum river watershed by LCM(land change modeler). Four data set, year of 2000, 2008, 2050 and 2100, of land use were used to claculate groundwater vulnerability. The land use map of 2000 and 2008 for Geum river watershed was made by using data provided from Water Management Information System (WAMIS) and National Spatial Information Clearinghouse and those of 2050 and 2100 were made by LCM prediction. The results of land change by LCM prediction showed 233% increase of resident area and 10% dcrease of field area indicating increase of groundwater vulnerability in Geum river area.

  6. The cloud-radiative forcing of the U.S. landfalling atmospheric rivers

    NASA Astrophysics Data System (ADS)

    Luo, Qianwen

    Atmospheric rivers (ARs) are narrow channels in the atmosphere that transport an enormous amount of moisture from the tropics to the higher latitudes. Streaks of highly reflective clouds are observed along with the ARs in satellite imagery. These clouds both influence the moisture transport of ARs, as well as modify the Earth-Atmospheric energy budget through pathways such as cloud-radiative forcing (CRF). This dissertation studies the CRF of the U.S. Landfalling ARs in weather and climate scales. Three crucial questions are addressed. First, how do clouds produced by the ARs modulate the moisture and heat balance of the Earth-Atmospheric system? Even though studies of ARs date back to the 90s, past research has been primarily focused on their hydrological impacts. We addressed this research gap by comparing the dominant types of precipitating clouds and convection of two ARs. Through quantifying their effects on the energy balance in the midlatitudes, we found that when deep convection was the dominant cloud types of an AR, impressive CRF cooling was produced. Second, what are the sufficient climate conditions for the extensive CRF in the continental U.S.? We studied 60 ARs that reached the California coast (the Southwest ARs) and 60 ARs that reached Pacific Northwest during Nov-Mar, 2000-2008. It was found that when these West-Coast ARs were followed by the moisture surge from the Gulf of Mexico (the Gulf-Coast AR), it resulted in apparent statewide CRF. Such condition happened more frequently in the Southwest-AR scenario. Third, how does the subgrid-scale-convection-induced CRF influence the moisture transport of ARs?We ran two WRF ARW simulations for a Southwest-AR that was followed by a Gulf-Coast AR. The only difference between the two simulations was one considered the CRF of subgrid-scale clouds while the other did not. By comparing the two simulations, we found that the subgrid-scale-convection-induced CRF helped prolong the lifespan of clouds in an AR

  7. Phenology Shifts at Start vs. End of Growing Season in Temperate Vegetation Over the Northern Hemisphere for the Period 1982-2008

    NASA Technical Reports Server (NTRS)

    Jeong, Su-Jong; Ho, Chang-Hoi; Gim, Hyeon-Ju; Brown, Molley E.

    2011-01-01

    Changes in vegetative growing seasons are dominant indicators of the dynamic response of ecosystems to climate change. Therefore, knowledge of growing seasons over the past decades is essential to predict ecosystem changes. In this study, the long-term changes in the growing seasons of temperate vegetation over the Northern Hemisphere were examined by analyzing satellite-measured normalized difference vegetation index and reanalysis temperature during 1982 2008. Results showed that the length of the growing season (LOS) increased over the analysis period; however, the role of changes at the start of the growing season (SOS) and at the end of the growing season (EOS) differed depending on the time period. On a hemispheric scale, SOS advanced by 5.2 days in the early period (1982-1999) but advanced by only 0.2 days in the later period (2000-2008). EOS was delayed by 4.3 days in the early period, and it was further delayed by another 2.3 days in the later period. The difference between SOS and EOS in the later period was due to less warming during the preseason (January-April) before SOS compared with the magnitude of warming in the preseason (June September) before EOS. At a regional scale, delayed EOS in later periods was shown. In North America, EOS was delayed by 8.1 days in the early period and delayed by another 1.3 days in the later period. In Europe, the delayed EOS by 8.2 days was more significant than the advanced SOS by 3.2 days in the later period. However, in East Asia, the overall increase in LOS during the early period was weakened in the later period. Admitting regional heterogeneity, changes in hemispheric features suggest that the longer-lasting vegetation growth in recent decades can be attributed to extended leaf senescence in autumn rather than earlier spring leaf-out. Keywords: climate change, growing season, NDVI (normalized difference vegetation index), Northern Hemisphere, phenology,

  8. Comparison of two landslide susceptibility assessments in the Champagne-Ardenne region (France)

    NASA Astrophysics Data System (ADS)

    Den Eeckhaut, M. Van; Marre, A.; Poesen, J.

    2010-02-01

    The vineyards of the Montagne de Reims are mostly planted on steep south-oriented cuesta fronts receiving a maximum of sun radiation. Due to the location of the vineyards on steep hillslopes, the viticultural activity is threatened by slope failures. This study attempts to better understand the spatial patterns of landslide susceptibility in the Champagne-Ardenne region by comparing a heuristic (qualitative) and a statistical (quantitative) model in a 1120 km² study area. The heuristic landslide susceptibility model was adopted from the Bureau de Recherches Géologiques et Minières, the GEGEAA - Reims University and the Comité Interprofessionnel du Vin de Champagne. In this model, expert knowledge of the region was used to assign weights to all slope classes and lithologies present in the area, but the final susceptibility map was never evaluated with the location of mapped landslides. For the statistical landslide susceptibility assessment, logistic regression was applied to a dataset of 291 'old' (Holocene) landslides. The robustness of the logistic regression model was evaluated and ROC curves were used for model calibration and validation. With regard to the variables assumed to be important environmental factors controlling landslides, the two models are in agreement. They both indicate that present and future landslides are mainly controlled by slope gradient and lithology. However, the comparison of the two landslide susceptibility maps through (1) an evaluation with the location of mapped 'old' landslides and through (2) a temporal validation with spatial data of 'recent' (1960-1999; n = 48) and 'very recent' (2000-2008; n = 46) landslides showed a better prediction capacity for the statistical model produced in this study compared to the heuristic model. In total, the statistically-derived landslide susceptibility map succeeded in correctly classifying 81.0% of the 'old' and 91.6% of the 'recent' and 'very recent' landslides. On the susceptibility map

  9. Absence of liver steatosis in HIV-HCV co-infected patients receiving regimens containing tenofovir or abacavir.

    PubMed

    Borghi, V; Bisi, L; Manzini, L; Cossarizza, A; Mussini, C

    2013-04-01

    In human immunodeficiency virus-hepatitis C virus (HIV-HCV) co-infected patients, steatosis has been independently associated with a number of antiretroviral drugs, including stavudine, especially in patients with non-3 HCV genotypes. We retrospectively investigated the presence of steatosis among HIV-HCV co-infected and HCV mono-infected patients, and the role of tenofovir disoproxil fumarate (TDF) or abacavir (ABC) in determining hepatic steatosis. Liver steatosis was retrospectively evaluated in all consecutive biopsies performed in the period 2000-2008 in HCV mono-infected and HIV-HCV co-infected patients. A steatosis rate of >5 % was considered to be significant, and a multivariate logistic analysis was performed to evaluate factors associated with steatosis. In total, 393 HCV-infected patients underwent liver biopsy during the study period, of whom 205 (52.2 %) were co-infected with HIV. A steatosis rate of >5 % was diagnosed in 33.0 % of HCV mono-infected and in 47.8 % of HIV-HCV co-infected patients (P = 0.003). The rate of steatosis was higher in patients resuming antiretroviral therapy (54.7 %) than in naïve patients (33.3 %; P = 0.006). When the overall population was considered, steatosis was associated to HCV genotype 3 [odds ratio (OR) 4.53, 95 % confidence interval (CI) 2.71-7.58; P < 0.001]. In terms of the use of nucleos(t)ide drugs in HIV co-infected patients, multivariate analysis showed that only in patients with HCV genotypes other than genotype 3 was steatosis related to the use of stavudine (OR 5.38, 95 % CI 1.18-24.53; P = 0.03). The use of TDF (OR 1.07, 95 % CI 0.39-2.88; P = 0.898) or ABC (OR 0.592, 95 % CI 0.09-4.07; P = 0.594) was not associated with steatosis. In HCV mono-infected and HIV-HCV co-infected patients, steatosis appears to be a virus-mediated effect of HCV genotype 3. In HIV patients infected with HCV genotypes other than genotype 3, the risk of developing steatosis was higher in those patients resuming antiretroviral

  10. Transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland.

    PubMed

    Héritier, Harris; Vienneau, Danielle; Foraster, Maria; Eze, Ikenna Collins; Schaffner, Emmanuel; Thiesse, Laurie; Rudzik, Franziska; Habermacher, Manuel; Köpfli, Micha; Pieren, Reto; Brink, Mark; Cajochen, Christian; Wunderli, Jean Marc; Probst-Hensch, Nicole; Röösli, Martin

    2017-04-01

    Most studies published to date consider single noise sources and the reported noise metrics are not informative about the peaking characteristics of the source under investigation. Our study focuses on the association between cardiovascular mortality in Switzerland and the three major transportation noise sources-road, railway and aircraft traffic-along with a novel noise metric termed intermittency ratio (IR), expressing the percentage contribution of individual noise events to the total noise energy from all sources above background levels. We generated Swiss-wide exposure models for road, railway and aircraft noise for 2001. Noise from the most exposed façade was linked to geocodes at the residential floor height for each of the 4.41 million adult (>30 y) Swiss National Cohort participants. For the follow-up period 2000-2008, we investigated the association between all noise exposure variables [Lden(Road), Lden(Rail), Lden(Air), and IR at night] and various cardiovascular primary causes of death by multipollutant Cox regression models adjusted for potential confounders including NO2. The most consistent associations were seen for myocardial infarction: adjusted hazard ratios (HR) (95% CI) per 10 dB increase of exposure were 1.038 (1.019-1.058), 1.018 (1.004-1.031), and 1.026 (1.004-1.048) respectively for Lden(Road), Lden(Rail), and Lden(Air). In addition, total IR at night played a role: HRs for CVD were non-significant in the 1st, 2nd and 5th quintiles whereas they were 1.019 (1.002-1.037) and 1.021 (1.003-1.038) for the 3rd and 4th quintiles. Our study demonstrates the impact of all major transportation noise sources on cardiovascular diseases. Mid-range IR levels at night (i.e. between continuous and highly intermittent) are potentially more harmful than continuous noise levels of the same average level.

  11. Varicella infection is not associated with increasing prevalence of eczema: a U.S. population-based study.

    PubMed

    Li, J C; Silverberg, J I

    2015-11-01

    Chickenpox infection early in childhood has previously been shown to protect against the development of childhood eczema in line with the hygiene hypothesis. In 1995, the American Academy of Pediatrics recommended routine vaccination against varicella zoster virus in the United States. Subsequently, rates of chickenpox infection have dramatically decreased in childhood. We sought to understand the impact of declining rates of chickenpox infection on the prevalence of eczema. We analysed data from 207 007 children in the 1997-2013 National Health Interview Survey. One-year prevalence of eczema and 'ever had' history of chickenpox were analysed. Associations between chickenpox infection and eczema were tested using survey-weighted logistic regression. The impact of chickenpox on trends of eczema prevalence was tested using survey logistic regression and generalized linear models. Children with a history of chickenpox compared with those without chickenpox had a lower prevalence [survey-weighted logistic regression (95% confidence interval, CI)] of eczema [8·8% (8·5-9·0%) vs. 10·6% (10·4-10·8%)]. In pooled multivariate models controlling for age, sex, race/ethnicity, household income, highest level of household education, insurance coverage, U.S. birthplace and family size, eczema was inversely associated with chickenpox [adjusted odds ratio (95% CI), 0·90 (0·86-0·94), P < 0·001]. The prevalence of eczema significantly increased over time (Tukey post-hoc test, P < 0·001 for comparisons of survey years 2001-13 vs. 1997-2000, 2008-13 vs. 2001-04 and 2008-13 vs. 2005-07). In multivariate generalized linear models, the odds of eczema was not associated with chickenpox in 2001-13 (P ≥ 0·06). These findings suggest that lower rates of chickenpox infection secondary to widespread vaccination against varicella zoster virus are not contributing to higher rates of childhood eczema in the U.S. © 2015 British Association of Dermatologists.

  12. High-resolution of trace elements (Mg, U, Sr, Ba and Zn) in speleothems as Holocene palaeoclimatic proxies: Père Noël cave, Belgium

    NASA Astrophysics Data System (ADS)

    Allan, Mohammed; Verheyden, Sophie; Riotte, Jean; Ghaleb, Bassam; Chmeleff, Jerome; fagel, Nathalie

    2013-04-01

    Speleothems are now regarded as valuable archives of climatic conditions on the continents, offering the advantages of absolute U-series dating relative to other continental climate proxy recorders such as lake sediments and peat cores. High spatial resolution measurements of Mg, U, Sr, Ba and Zn were realized by laser-ablation inductively coupled plasma mass spectrometry in the Belgian Père Noël cave Holocene stalagmite (Verheyden et al., 2000, 2008). The stalagmite of 65 cm long was deposited from ~12000 years to ~2000 years dated by U/Th method. Mg, Sr, Ba, U, and Zn are known as indicators for hydrological conditions (e.g. Ayalon et al., 1999; Fairchild et al., 2000). Mg, Sr, Ba concentrations are positively correlated (r> 0.7) with similar changes in the δ 13C implying similar processes influence their concentration changes. U has an inverse relationship with δ 13C. The study suggests that trace elements in the Père Noël stalagmite have the potential to provide high resolution insights into variability in water recharge during the Holocene. References Ayalon A., Bar-Matthews M. and Kaufman A., 1999. Petrography, strontium, barium and uranium concentrations, and strontium and uranium isotope ratios in speleothems as palaeoclimatic proxies: Soreq cave, Israel. The Holocene 9 (6), 715-722. Fairchild I.J., Borsato A., Tooth A.F.,Frisia S., Hawkesworth C.J., Huang Y., Mcdermott F. and Spiro B., 2000. Controls on trace element (Sr-Mg) compositions of carbonate cave waters: implications for speleothem climatic records. Chemical Geology 166, 255-269. Verheyden S., Keppens E. , Fairchild I.J., Mc Dermott F. and D. Weis, 2000. Sr isotope geochemistry of a Belgian Holocene speleothem: implications for paleoclimate reconstructions. Chemical Geology, 169: 131 144. Verheyden S., Genty D., Deflandre G., Quinif Y. and Keppens E., 2008. Monitoring climatological, hydrological and geochemical parameters in the Père Noël cave (Belgium): Implication for the interpretation

  13. Characteristics of hospitals diverting ambulances in a California EMS system.

    PubMed

    Kahn, Christopher A; Stratton, Samuel J; Anderson, Craig L

    2014-02-01

    While several reports discuss controversies regarding ambulance diversion from acute care hospitals and the mortality, financial, and resource effects, there is scant literature related to the effect of hospital characteristics. The objective of this study was to describe specific paramedic receiving center characteristics that are associated with ambulance diversion rates in an Emergency Medical Services system. A retrospective observational study design was used. The study was performed in a suburban EMS system with 27 paramedic receiving centers studied; one additional hospital present at the beginning of the study period (2000-2008) was excluded due to lack of recent data. Hospital-level and population-level characteristics were gathered, including diversion rate (hours on diversion/total hours open), for-profit status, number of specialty services (including trauma, burn, cardiovascular surgery, renal transplant services, cardiac catheterization capability [both interventional and diagnostic], and burn surgery), average inpatient bed occupancy rate (total patient days/licensed bed days), annual emergency department (ED) volume (patients per year), ED admission rate (percent of ED patients admitted), and percent of patients leaving without being seen. Demographic characteristics included percent of persons in each hospital's immediate census tract below the 100% and 200% poverty lines (each considered separately), and population density within the census tract. Bivariate and regression analyses were performed. Diversion rates for the 27 centers ranged from 0.3%-14.5% (median 4.5%). Average inpatient bed occupancy rate and presence of specialty services were correlated with an increase in diversion rate; occupancy rate showed a 0.08% increase in diversion hours per 1% increase in occupancy rate (95% CI, 0.01%-0.16%), and hospitals with specialty services had, on average, a 4.1% higher diversion rate than other hospitals (95% CI, 1.6%-6.7%). Other characteristics

  14. Does the simple dynamical systems approach provide useful information about catchment hydrological functioning in a Mediterranean context? Application to the Ardèche catchment (France)

    NASA Astrophysics Data System (ADS)

    Adamovic, M.; Braud, I.; Branger, F.; Kirchner, J. W.

    2014-09-01

    This study explores how catchment heterogeneity and variability can be summarized in simplified models, representing the dominant hydrological processes. It focuses on Mediterranean catchments, characterized by heterogeneous geology, pedology, and land use, as well as steep topography and a rainfall regime in which summer droughts contrast with high-rainfall periods in autumn. The Ardèche catchment (south-east France), typical of this environment, is chosen to explore the following questions: (1) can such a Mediterranean catchment be adequately characterized by simple dynamical systems approach and what are the limits of the method under such conditions? (2) What information about dominant predictors of hydrological variability can be retrieved from this analysis in such catchments? In this work we apply the data-driven approach of Kirchner (WRR, 2009) to estimate discharge sensitivity functions that summarize the behavior of four sub-catchments of the Ardèche, using non-vegetation periods (November-March) from 9 years of data (2000-2008) from operational networks. The relevance of the inferred sensitivity function is assessed through hydrograph simulations, and through estimating precipitation rates from discharge fluctuations. We find that the discharge-sensitivity function is downward-curving in double-logarithmic space, thus allowing further simulation of discharge and non-divergence of the model, only during non-vegetation periods. The analysis is complemented by a Monte-Carlo sensitivity analysis showing how the parameters summarizing the discharge sensitivity function impact the simulated hydrographs. The resulting discharge simulation results are good for granite catchments, found to be predominantly characterized by saturation excess runoff and sub-surface flow processes. The simple dynamical system hypothesis works especially well in wet conditions (peaks and recessions are well modeled). On the other hand, poor model performance is associated with

  15. Assessing the simple dynamical systems approach in a Mediterranean context: application to the Ardeche catchment (France)

    NASA Astrophysics Data System (ADS)

    Adamovic, M.; Braud, I.; Branger, F.; Kirchner, J. W.

    2015-05-01

    This study explores how catchment heterogeneity and variability can be summarized in simplified models, representing the dominant hydrological processes. It focuses on Mediterranean catchments, characterized by heterogeneous geology, pedology and land use, as well as steep topography and a rainfall regime in which summer droughts contrast with high-rainfall periods in autumn. The Ardeche catchment (Southeast France), typical of this environment, is chosen to explore the following questions: (1) can such a Mediterranean catchment be adequately characterized by a simple dynamical systems approach and what are the limits of the method under such conditions? (2) what information about dominant predictors of hydrological variability can be retrieved from this analysis in such catchments? In this work we apply the data-driven approach of Kirchner (2009) to estimate discharge sensitivity functions that summarize the behaviour of four sub-catchments of the Ardeche, using low-vegetation periods (November-March) from 9 years of measurements (2000-2008) from operational networks. The relevance of the inferred sensitivity function is assessed through hydrograph simulations, and through estimating precipitation rates from discharge fluctuations. We find that the discharge sensitivity function is downward-curving in double-logarithmic space, thus allowing further simulation of discharge and non-divergence of the model, only during low-vegetation periods. The analysis is complemented by a Monte Carlo sensitivity analysis showing how the parameters summarizing the discharge sensitivity function impact the simulated hydrographs. The resulting discharge simulation results are good for granite catchments, which are likely to be characterized by shallow subsurface flow at the interface between soil and bedrock. The simple dynamical system hypothesis works especially well in wet conditions (peaks and recessions are well modelled). On the other hand, poor model performance is associated

  16. Rates of obstetric intervention during birth and selected maternal and perinatal outcomes for low risk women born in Australia compared to those born overseas.

    PubMed

    Dahlen, Hannah G; Schmied, Virginia; Dennis, Cindy-Lee; Thornton, Charlene

    2013-05-01

    There are mixed reports in the literature about obstetric intervention and maternal and neonatal outcomes for migrant women born in resource rich countries. The aim of this study was to compare the risk profile, rates of obstetric intervention and selected maternal and perinatal outcomes for low risk women born in Australia compared to those born overseas. A population-based descriptive study was undertaken in NSW of all singleton births recorded in the NSW Midwives Data Collection between 2000-2008 (n=691,738). Risk profile, obstetric intervention rates and selected maternal and perinatal outcomes were examined. Women born in Australia were slightly younger (30 vs 31 years), less likely to be primiparous (41% vs 43%), three times more likely to smoke (18% vs 6%) and more likely to give birth in a private hospital (26% vs 18%) compared to women not born in Australia. Among the seven most common migrant groups to Australia, women born in Lebanon were the youngest, least likely to be primiparous and least likely to give birth in a private hospital. Hypertension was lowest amongst Vietnamese women (3%) and gestational diabetes highest amongst women born in China (14%). The highest caesarean section (31%), instrumental birth rates (16%) and episiotomy rates (32%) were seen in Indian women, along with the highest rates of babies <10th centile (22%) and <3rd centile (8%). Lebanese women had the highest rates of stillbirth (7.2/1000). Similar trends were found in the different migrant groups when only low risk women were included. The results suggest there are significant differences in risk profiles, obstetric intervention rates and maternal and neonatal outcomes between Australian-born and women born overseas and these differences are seen overall and in low risk populations. The finding that Indian women (the leading migrant group to Australia) have the lowest normal birth rate and high rates of low birth weight babies is concerning, and attention needs to be focused

  17. Alpha Virginis: line-profile variations and orbital elements

    NASA Astrophysics Data System (ADS)

    Harrington, David; Koenigsberger, Gloria; Olguín, Enrique; Ilyin, Ilya; Berdyugina, Svetlana V.; Lara, Bruno; Moreno, Edmundo

    2016-05-01

    Context. Alpha Virginis (Spica) is a B-type binary system whose proximity and brightness allow detailed investigations of the internal structure and evolution of stars undergoing time-variable tidal interactions. Previous studies have led to the conclusion that the internal structure of Spica's primary star may be more centrally condensed than predicted by theoretical models of single stars, raising the possibility that the interactions could lead to effects that are currently neglected in structure and evolution calculations. The key parameters in confirming this result are the values of the orbital eccentricity e, the apsidal period U, and the primary star's radius, R1. Aims: The aim of this paper is to analyze the impact that Spica's line profile variability has on the derivation of its orbital elements and to explore the use of the variability for constraining R1. Methods: We use high signal-to-noise and high spectral resolution observations obtained in 2000, 2008, and 2013 to derive the orbital elements from fits to the radial velocity curves. We produce synthetic line profiles using an ab initio tidal interaction model. Results: The general variations in the line profiles can be understood in terms of the tidal flows, whose large-scale structure is relatively fixed in the rotating binary system reference frame. Fits to the radial velocity curves yield e = 0.108 ± 0.014. However, the analogous RV curves from theoretical line profiles indicate that the distortion in the lines causes the fitted value of e to depend on the argument of periastron; i.e., on the epoch of observation. As a result, the actual value of e may be as high as 0.125. We find that U = 117.9 ± 1.8, which is in agreement with previous determinations. Using the value R1 = 6.8 R⊙ derived by Palate et al. (2013) the value of the observational internal structure constant k2,obs is consistent with theory. We confirm the presence of variability in the line profiles of the secondary star. RV

  18. Valorization of genetic variability for the qualitative improvement of autochthonous grape cultivars of Cirò's terroir through the self-fertilization.

    PubMed

    Meneghetti, Stefano; Gaiotti, Federica; Giust, Mirella; Belfiore, Nicola; Tomasi, Diego

    2015-03-01

    This study uses PCR-derived marker systems to investigate the genetic differences of 22 grapevine accessions obtained through a self-fertilization program using Gaglioppo and Magliocco dolce. The aim of the study was to improve some qualitative parameters, while preserving the adaptive characteristics of these two cultivars to the adverse environmental conditions of the Calabria region (southern Italy). These two Calabrian grapevines have been cultivated within a restricted area and have been placed under a strong anthropic pressure which has limited their phenotypical variability with no selection of higher performant biotypes. Therefore, to have accessions with improved qualitative traits, a program of genetic improvement based on the self-fertilization of Gaglioppo and Magliocco dolce cultivars was performed in 1998, producing 3,122 accessions. Selection cycles were performed in 14 years. A first selection cycle (1998-2000), based on visual inspection of vegetative traits, selected 1,320 accessions, planted in an experimental vineyard in 2000. A second selection cycle (2000-2008), based on phenotypic traits, sanitary aspects, and chemical composition of the grapes, selected 42 accessions, planted in a new experimental vineyard in 2008. A final selection cycle (2008-2012), produced 22 accessions (virus free), with the best agronomic, sanitary, and qualitative aspects: two accessions obtained from Gaglioppo have been selected by color characteristics (i.e., anthocyanin total content and stability); 20 genotypes obtained from Magliocco dolce had a better macro-composition of the grape (i.e., good sugar content with a balanced acidity). SSR analyses were performed to check the self-fertilization process. The study of genetic differences between accessions was performed by AFLPs, SAMPLs, and M-AFLPs. The application of the above-mentioned techniques allowed both to discriminate molecularly the 22 accessions grouped these accessions according to their genetic

  19. A Novel Method for Assessing Task Complexity in Outpatient Clinical-Performance Measures.

    PubMed

    Hysong, Sylvia J; Amspoker, Amber B; Petersen, Laura A

    2016-04-01

    Clinical-performance measurement has helped improve the quality of health-care; yet success in attaining high levels of quality across multiple domains simultaneously still varies considerably. Although many sources of variability in care quality have been studied, the difficulty required to complete the clinical work itself has received little attention. We present a task-based methodology for evaluating the difficulty of clinical-performance measures (CPMs) by assessing the complexity of their component requisite tasks. Using Functional Job Analysis (FJA), subject-matter experts (SMEs) generated task lists for 17 CPMs; task lists were rated on ten dimensions of complexity, and then aggregated into difficulty composites. Eleven outpatient work SMEs; 133 VA Medical Centers nationwide. Clinical Performance: 17 outpatient CPMs (2000-2008) at 133 VA Medical Centers nationwide. Measure Difficulty: for each CPM, the number of component requisite tasks and the average rating across ten FJA complexity scales for the set of tasks comprising the measure. Measures varied considerably in the number of component tasks (M = 10.56, SD = 6.25, min = 5, max = 25). Measures of chronic care following acute myocardial infarction exhibited significantly higher measure difficulty ratings compared to diabetes or screening measures, but not to immunization measures ([Formula: see text] = 0.45, -0.04, -0.05, and -0.06 respectively; F (3, 186) = 3.57, p = 0.015). Measure difficulty ratings were not significantly correlated with the number of component tasks (r = -0.30, p = 0.23). Evaluating the difficulty of achieving recommended CPM performance levels requires more than simply counting the tasks involved; using FJA to assess the complexity of CPMs' component tasks presents an alternate means of assessing the difficulty of primary-care CPMs and accounting for performance variation among measures and performers. This in turn could be used in designing

  20. Autologous Bone Marrow Mononuclear Cells Reduce Therapeutic Intensity for Severe Traumatic Brain Injury in Children

    PubMed Central

    Liao, George P.; Harting, Matthew T.; Hetz, Robert A.; Walker, Peter A.; DO, Shinil K. Shah; Corkins, Christopher J.; Hughes, Travis G.; Jimenez, Fernando; Kosmach, Steven C.; Day, Mary-Clare; Tsao, KuoJen; Lee, Dean A.; Worth, Laura L.; Baumgartner, James E.; Cox, Charles S.

    2014-01-01

    Objective The devastating effect of traumatic brain injury (TBI) is exacerbated by an acute secondary neuroinflammatory response, clinically manifest as elevated intracranial pressure (ICP) due to cerebral edema. The treatment effect of cell based therapies in the acute post-TBI period has not been clinically studied although preclinical data demonstrate that bone marrow derived mononuclear cell (BMMNC) infusion downregulates the inflammatory response. Our study evaluates whether pediatric TBI patients receiving intravenous, autologous BMMNCs within 48 hours of injury experienced a reduction in therapeutic intensity directed towards managing elevated ICP relative to matched controls. Design The study was a retrospective cohort design comparing pediatric patients in a Phase I clinical trial treated with intravenous autologous BMMNCs (n=10) to a control group of age and severity matched children (n=19). Setting The study setting was at Children's Memorial Hermann Hospital, an American College of Surgeons Level 1 Pediatric Trauma Center and teaching hospital for the University of Texas Health Science Center at Houston from 2000-2008. Patients Study patients were 5-14 years with post resuscitation Glasgow Coma Scale scores of 5-8. Interventions The treatment group received 6 million autologous BMMNC/kg body weight intravenously within 48 hours of injury. The control group was treated in an identical fashion, per standard of care, guided by our TBI management protocol, derived from American Association of Neurological Surgeons guidelines. Measurements The primary measure was the Pediatric Intensity Level of Therapy (PILOT) scale, used to quantify treatment of elevated ICP. Secondary measures included the Pediatric Logistic Organ Dysfunction (PELOD) score and days of ICP monitoring as a surrogate for length of neurointensive care. Main Results A repeated measure mixed model with marginal linear predictions identified a significant reduction in the PILOT score beginning

  1. A reduction in chronic hepatitis B virus infection prevalence among children in Vietnam demonstrates the importance of vaccination.

    PubMed

    Nguyen, Tran Hien; Vu, Minh Huong; Nguyen, Van Cuong; Nguyen, Lien Huong; Toda, Kohei; Nguyen, Tuyet Nga; Dao, Sang; Wannemuehler, Kathleen A; Hennessey, Karen A

    2014-01-03

    Vietnam has high endemic hepatitis B virus infection with >8% of adults estimated to have chronic infection. Hepatitis B vaccine was first introduced in the national childhood immunization program in 1997 in high-risk areas, expanded nationwide in 2002, and included birth dose vaccination in 2003. This survey aimed to assess the impact of Vietnam's vaccination programme by estimating the prevalence of hepatitis B surface antigen (HBsAg) among children born during 2000-2008. This nationally representative cross-sectional survey sampled children based on a stratified three-stage cluster design. Demographic and vaccination data were collected along with a whole blood specimen that was collected and interpreted in the field with a point-of-care HBsAg test. A total of 6,949 children were included in the survey analyses. The overall HBsAg prevalence among surveyed children was 2.70% (95% confidence interval (CI): 2.20-3.30). However, HBsAg prevalence was significantly higher among children born in 2000-2003 (3.64%) compared to children born 2007-2008 (1.64%) (prevalence ratio (PR: 2.22, CI 1.55-3.18)). Among all children included in the survey, unadjusted HBsAg prevalence among children with ≥3 doses of hepatitis B vaccine including a birth dose (1.75%) was significantly lower than among children with ≥3 doses of hepatitis B vaccine but lacked a birth dose (2.98%) (PR: 1.71, CI: 1.00-2.91) and significantly lower than among unvaccinated children (3.47%) (PR: 1.99, CI: 1.15-3.45). Infants receiving hepatitis B vaccine >7 days after birth had significantly higher HBsAg prevalence (3.20%) than those vaccinated 0-1 day after birth (1.52%) (PR: 2.09, CI: 1.27-3.46). Childhood chronic HBV infection prevalence has been markedly reduced in Vietnam due to vaccination. Further strengthening of timely birth dose vaccination will be important for reducing chronic HBV infection prevalence of under 5 children to <1%, a national and Western Pacific regional hepatitis B control goal

  2. Detecting Changes of Thermal Environment over the Bohai Coastal Region by Spectral Change Vector Analysis

    NASA Astrophysics Data System (ADS)

    Hu, Y.; Jia, G.

    2009-12-01

    intensifier in major cities, such as Beijing and Tianjin. Further, the continual drier climate combined with human actions over past fifties years have intensified land thermal pattern change and the continuation will be an important aspects to understand land surface processes and local climate change. Land surface temperature trends from 2000-2008 over the Bohai coastal region

  3. Phenology Shifts at Start vs. End of Growing Season in Temperate Vegetation Over the Northern Hemisphere for the Period 1982-2008

    NASA Technical Reports Server (NTRS)

    Jeong, Su-Jong; Ho, Chang-Hoi; Gim, Hyeon-Ju; Brown, Molley E.

    2011-01-01

    Changes in vegetative growing seasons are dominant indicators of the dynamic response of ecosystems to climate change. Therefore, knowledge of growing seasons over the past decades is essential to predict ecosystem changes. In this study, the long-term changes in the growing seasons of temperate vegetation over the Northern Hemisphere were examined by analyzing satellite-measured normalized difference vegetation index and reanalysis temperature during 1982 2008. Results showed that the length of the growing season (LOS) increased over the analysis period; however, the role of changes at the start of the growing season (SOS) and at the end of the growing season (EOS) differed depending on the time period. On a hemispheric scale, SOS advanced by 5.2 days in the early period (1982-1999) but advanced by only 0.2 days in the later period (2000-2008). EOS was delayed by 4.3 days in the early period, and it was further delayed by another 2.3 days in the later period. The difference between SOS and EOS in the later period was due to less warming during the preseason (January-April) before SOS compared with the magnitude of warming in the preseason (June September) before EOS. At a regional scale, delayed EOS in later periods was shown. In North America, EOS was delayed by 8.1 days in the early period and delayed by another 1.3 days in the later period. In Europe, the delayed EOS by 8.2 days was more significant than the advanced SOS by 3.2 days in the later period. However, in East Asia, the overall increase in LOS during the early period was weakened in the later period. Admitting regional heterogeneity, changes in hemispheric features suggest that the longer-lasting vegetation growth in recent decades can be attributed to extended leaf senescence in autumn rather than earlier spring leaf-out. Keywords: climate change, growing season, NDVI (normalized difference vegetation index), Northern Hemisphere, phenology,

  4. Long-term trends in suspended chlorophyll a and vertical particle flux with respect to changing physical conditions in eastern Fram Strait, Arctic Ocean

    NASA Astrophysics Data System (ADS)

    Nöthig, Eva-Maria; Bauerfeind, Eduard; Beszczynska-Möller, Agnieszka; Kraft, Angelina; Bracher, Astrid; Cherkasheva, Alexandra; Fahl, Kirsten; Hardge, Kristin; Kaleschke, Lars; Lalande, Catherine; Metfies, Katja; Peeken, Ilka; Klages, Michael; Soltwedel, Thomas

    2014-05-01

    The Fram Strait is the main gateway for water, heat, sea ice and plankton exchanges between the Arctic Ocean and the North Atlantic. The abundance and composition of phyto- and zooplankton communities is governed to a large extent by key physical factors such as water temperature, salinity, currents, stratification of the water column and the presence or absence of sea ice. With our study we aim at tracing effects of environmental changes in pelagic system structure and impacts on the fate of organic matter produced in the upper water column in a region that is anticipated to react rapidly to climate change. Chlorophyll a, an indicator of biomass standing stock of phytoplankton, has been measured in the upper 100 m of the water column since 1991 during several summer cruises (with RV 'Polarstern') across Fram Strait. Chlorophyll a measurements are used to validate productivity estimates by remote sensing from space. The quantity and composition of export fluxes of organic matter including biomarker have been measured since 2000 by annually moored sediment traps deployed at 200-300m at the AWI long-term observatory HAUSGARTEN in eastern Fram Strait (79°/4°E). Along with sinking particles, zooplankton (so-called 'swimmers') was also caught in the traps. Analyses of the material collected by the sediment traps allowed us to track seasonal and inter-annual changes in the surface waters at HAUSGARTEN. We present temporal trends in the chlorophyll a distribution (1991-2012), in swimmer composition in the traps (2000-2009), and in the export of biomarker (2000-2008), particulate organic carbon, particulate biogenic silica, calcium carbonate, and the protist composition (2000-2012), in relation to the changing sea ice cover and water temperature. Whereas chlorophyll a (integrated values 0-100m) showed only a slight increase, the swimmer composition and the composition of the annual particle flux changed after a warm water event occurring from 2005-2007. The warm anomaly

  5. Changes in Continental Water Storage Caused by Groundwater Depletion Since 1900

    NASA Astrophysics Data System (ADS)

    Konikow, L. F.

    2011-12-01

    Development of groundwater resources for agricultural, industrial, and municipal purposes greatly expanded in the last century, and economic gains from groundwater use have been dramatic. In many places, however, groundwater reserves have been depleted to the extent that water levels have declined tens to hundreds of meters, well yields have decreased, and pumping costs have increased. These impacts tend to reduce the efficiency and sustainability of groundwater development. Much groundwater pumped from confined aquifers is derived from storage losses in adjacent low-permeability confining layers. Depletion in confining layers is difficult to estimate and rarely monitored, but it can greatly exceed the depletion from the confined aquifer itself and groundwater drainage from confining layers is partly irreversible. For example, in the confined Dakota Aquifer, about 98 percent of the water removed from storage was derived from depletion in adjacent confining units. If cumulative long-term regional and global groundwater depletion is large, it will represent a substantial net transfer of water mass from land to the oceans, thereby contributing to sea-level rise. A U.S. national groundwater depletion census was made primarily using direct volumetric approaches; results indicate that about 800 km3 of water was depleted from groundwater systems in the U.S. during the 20th century-equivalent to a sea-level rise of approximately 2.2 mm-and 1,000 km3 through 2008. Cumulative global groundwater depletion since 1900 totals about 3,400 km3 through 2000 and 4,500 km3 through 2008 (equivalent to a sea-level rise of 12.6 mm). The rate of annual depletion has increased markedly since about 1950, with maximum rates occurring during the most recent period (2000-2008), when they averaged about 145 km3/yr (equivalent to 0.40 mm/yr of sea-level rise, or 13% of the reported rate of 3.1 mm/yr during this recent period). Overall, the volume and rate of estimated long-term global

  6. A comparison of methods for smoothing and gap filling time series of remote sensing observations: application to MODIS LAI products

    NASA Astrophysics Data System (ADS)

    Kandasamy, S.; Baret, F.; Verger, A.; Neveux, P.; Weiss, M.

    2012-12-01

    Moderate resolution satellite sensors including MODIS already provide more than 10 yr of observations well suited to describe and understand the dynamics of the Earth surface. However, these time series are incomplete because of cloud cover and associated with significant uncertainties. This study compares eight methods designed to improve the continuity by filling gaps and the consistency by smoothing the time course. It includes methods exploiting the time series as a whole (Iterative caterpillar singular spectrum analysis (ICSSA), empirical mode decomposition (EMD), low pass filtering (LPF) and Whittaker smoother (Whit)) as well as methods working on limited temporal windows of few weeks to few months (Adaptive Savitzky-Golay filter (SGF), temporal smoothing and gap filling (TSGF) and asymmetric Gaussian function (AGF)) in addition to the simple climatological LAI yearly profile (Clim). Methods were applied to MODIS leaf area index product for the period 2000-2008 over 25 sites showing a large range of seasonal patterns. Performances were discussed with emphasis on the balance achieved by each method between accuracy and roughness depending on the fraction of missing observations and the length of the gaps. Results demonstrate that EMD, LPF and AGF methods were failing in case of significant fraction of gaps (%Gap > 20%), while ICSSA, Whit and SGF were always providing estimates for dates with missing data. TSGF (respectively Clim) was able to fill more than 50% of the gaps for sites with more than 60% (resp. 80%) fraction of gaps. However, investigation of the accuracy of the reconstructed values shows that it degrades rapidly for sites with more than 20% missing data, particularly for ICSSA, Whit and SGF. In these conditions, TSGF provides the best performances significantly better than the simple Clim for gaps shorter than about 100 days. The roughness of the reconstructed temporal profiles shows large differences between the several methods, with a decrease

  7. A comparison of methods for smoothing and gap filling time series of remote sensing observations - application to MODIS LAI products

    NASA Astrophysics Data System (ADS)

    Kandasamy, S.; Baret, F.; Verger, A.; Neveux, P.; Weiss, M.

    2013-06-01

    Moderate resolution satellite sensors including MODIS (Moderate Resolution Imaging Spectroradiometer) already provide more than 10 yr of observations well suited to describe and understand the dynamics of earth's surface. However, these time series are associated with significant uncertainties and incomplete because of cloud cover. This study compares eight methods designed to improve the continuity by filling gaps and consistency by smoothing the time course. It includes methods exploiting the time series as a whole (iterative caterpillar singular spectrum analysis (ICSSA), empirical mode decomposition (EMD), low pass filtering (LPF) and Whittaker smoother (Whit)) as well as methods working on limited temporal windows of a few weeks to few months (adaptive Savitzky-Golay filter (SGF), temporal smoothing and gap filling (TSGF), and asymmetric Gaussian function (AGF)), in addition to the simple climatological LAI yearly profile (Clim). Methods were applied to the MODIS leaf area index product for the period 2000-2008 and over 25 sites showed a large range of seasonal patterns. Performances were discussed with emphasis on the balance achieved by each method between accuracy and roughness depending on the fraction of missing observations and the length of the gaps. Results demonstrate that the EMD, LPF and AGF methods were failing because of a significant fraction of gaps (more than 20%), while ICSSA, Whit and SGF were always providing estimates for dates with missing data. TSGF (Clim) was able to fill more than 50% of the gaps for sites with more than 60% (80%) fraction of gaps. However, investigation of the accuracy of the reconstructed values shows that it degrades rapidly for sites with more than 20% missing data, particularly for ICSSA, Whit and SGF. In these conditions, TSGF provides the best performances that are significantly better than the simple Clim for gaps shorter than about 100 days. The roughness of the reconstructed temporal profiles shows large

  8. [The effects of 16-weeks pilates mat program on anthropometric variables and body composition in active adult women after a short detraining period].

    PubMed

    Vaquero-Cristóbal, Raquel; Alacid, Fernando; Esparza-Ros, Francisco; Muyor, José M; López-Miñarro, Pedro Ángel

    2015-04-01

    Introducción: Estudios previos han analizado los efectos de la práctica de Pilates mat sobre las variables antropométricas y la composición corporal en poblaciones sedentarias. No existen estudios sobre los beneficios del Pilates en estas varibles tras un corto periodo de desentrenamiento. Objetivo: Determinar el efecto un programa de 16 semanas de Pilates mat sobre las variables antropométricas, la composición coporal y el somatotipo, en mujeres adultas con experiencia previa tras 3 semanas de desentrenamiento. Metodología: A veintiuna mujeres se les realizó una valoración antropométrica completa siguiendo las indicaciones de la ISAK antes y después de un programa de Pilates mat de 16 semanas (2 días a la semana, una hora por día). Todas las mujeres tenían una experiencia previa en la práctica de Pilates mat de entre 1 y 3 años y venían de un proceso de desentrenamiento de 3 semanas (vacaciones de Navidad). Resultados y discusión: Las mujeres mostraron una reducción significativa del peso corporal, el IMC, los pliegues cutáneos individuales del miembro superior (bíceps y tríceps) y el tronco (subescapular, cresta iliaca, supraespinal y abdominal), el sumatorio de 6 y 8 pliegues, la endomorfia y la masa grasa; y un aumento significativo de la masa muscular. El somatotipo medio se clasificó en meso-endomorfo para el pre- (4,91, 4,01, 1,47) y el post-test (4,68, 4,16, 1,69). Ocho mujeres cambiaron su clasificación del somatotipo tras el programa de intervención. Conclusiones: La práctica de Pilates mat durante 16 semanas provocó cambios asociados a una mejora del estado de salud en las variables antropométricas, sobre todo en los pliegues cutáneos que disminuyeron significativamente, la composición corporal (masa grasa y muscular, que disminuyeron y aumentaron, respectivamente) y el somatotipo (una reducción significativa del componente endomórfico) en mujeres con experiencia previa en la práctica de Pilates después de tres semanas

  9. [DIETARY HABITS AND FEEDING BELIEFS OF PEOPLE WITH CROHN'S DISEASE].

    PubMed

    García-Sanjuán, Sofía; Lillo-Crespo, Manuel; Sanjuán-Quiles, Ángela; Richart-Martínez, Miguel

    2015-12-01

    Introducción: la enfermedad de Crohn es una enfermedad crónica de etiopatogenia desconocida. Las consecuencias que esta enfermedad provoca a nivel nutricional dependen de varios factores. Sin embargo, poco se sabe sobre las prácticas nutricionales que adoptan estos pacientes una vez diagnosticados. Objetivo: explorar la experiencia de los afectados en relación con la ingesta alimentaria, con el objetivo futuro de comprender dichas experiencias y diseñar intervenciones eficaces y adecuadas. Metodología y sujetos: se empleó un diseño cualitativo basado en el enfoque etnográfico. Se realizaron 19 entrevistas semiestructuradas, hasta conseguir la saturación de la información, a afectados por la enfermedad de Crohn, en la provincia de Alicante y, posteriormente, se realizó el análisis temático. Resultados: cinco categorías con sus respectivas subcategorías de análisis fueron identificadas a partir de los datos sobre la experiencia de alimentación de las personas entrevistadas. 1) Creencias sobre nutrición y EC, 2) Modificación de los hábitos alimentarios, 3) Búsqueda de información sobre alimentación y EC, 4) El papel de los profesionales, 5) Autogestión. Conclusiones: el conocimiento de los hábitos dietéticos de la persona con EC en una población en la que su dieta se presupone que culturalmente es reconocida como saludable, nos puede dar pautas de abordaje o apoyo profesional tanto en materia de prevención, promoción y educación para la salud, así como sobre su nivel organizativo en las instituciones sanitarias, cosas que actualmente no se tienen en cuenta, puesto que el abordaje de la EC es meramente clínico y con enfoque patológico, pero no desde una perspectiva de salud, fomentando hábitos saludables desde la multidisciplinariedad.

  10. [Haemorrhagic pineal cysts: two clinical cases successfully treated by means of microsurgery].

    PubMed

    Arevalo, A; Pulido-Rivas, P; Gilo-Arrojo, F; Sola, R G

    2016-09-01

    Introduccion. Los quistes pineales son un hallazgo incidental relativamente frecuente en las pruebas de imagen; sin embargo, la apoplejia pineal se considera rara y se asocia a sintomas graves. Casos clinicos. Varon de 25 a˜os y mujer de 15 a˜os, que acudieron a urgencias con clinica de hipertension intracraneal; mediante pruebas de imagen se confirmo la existencia de una hemorragia pineal. Se les trato con exito mediante microcirugia. Conclusion. En nuestra experiencia, y avalado por la bibliografia, creemos que el mejor tratamiento de esta infrecuente patologia es el abordaje microquirurgico. Sin embargo, no se excluye la posibilidad de que, en un futuro, las tecnicas endoscopicas puedan tener un lugar importante en el tratamiento de la apoplejia pineal.

  11. Eight years of bioethics

    PubMed Central

    Moreno-Exebio, Luis

    2012-01-01

    Este trabajo presenta la experiencia que significó el paso por el Programa Internacional de Formación en Ética de la investigación biomédica y psicosocial del Centro Interdisciplinario de Estudios en Bioética de la Universidad de Chile (2003–2004) y algunas reflexiones respecto de la integración de lo aprendido en mi posterior labor en comités de ética y programas académicos de ética de investigación. Asimismo, en la elaboración de regulaciones que permitan una mejor evaluación ética y científica. PMID:23172984

  12. Pedagogia artistica: la conceptualizacion y la creatividad en estudiantes de ciencias de sexto grado

    NASA Astrophysics Data System (ADS)

    Ortiz Colon, Edwin A.

    Se realizo un estudio fenomenologico sobre la conceptualizacion, la creatividad y el valor del dibujo en propiciar un contexto creativo para el aprendizaje de ciencias de sexto grado. La conceptualizacion se interpreto como un proceso que ocurre en las relaciones que los estudiantes establecen entre los temas de estudio y las ideas principales, las experiencias previas, las creencias personales, el tiempo y el valor de la conservacion ambiental. La esencia de la creatividad se definio en funcion de la imaginacion, las destrezas, la intencion, la libertad de pensamiento y expresion y el contexto. El dibujo propicio un ambiente creativo de aprendizaje en las ciencias al facilitar el uso del pensamiento cientifico profundo, el inquirir artistico y la expresion libre.

  13. Micosis fungoide e inhibidores del TNFα: ¿riesgo o beneficio?

    PubMed

    Maroñas-Jiménez, Lidia; Burillo-Martínez, Sara; Tous-Romero, Fátima; Rodríguez-Peralto, Jose Luis; Ortiz de Frutos, Javier; Ortiz-Romero, Pablo Luis

    2016-05-15

    The growing use of anti-TNF drugs during the last years has reopened the discussion about the possible increased risk of developing non-Hodgkin lymphoma in patients with such type of treatments. We present our clinical experience and critical opinion about the current situation of such issue regarding cutaneous T-cell lymphomas.El creciente uso de fármacos anti-TNF durante los últimos años ha reabierto el debate sobre el posible aumento de riesgo de linfomas no Hodgkin en los pacientes con este tipo de tratamientos. Presentamos nuestra experiencia clínica y opinión critica sobre la situación actual de este tema en relación a los linfomas cutáneos de células T.

  14. Scenario approximation in a phenomenological study in Mexico: experience report.

    PubMed

    Guerrero-Castañeda, Raúl Fernando; Menezes, Tânia Maria de Oliva; Vargas, Ma Guadalupe Ojeda

    2017-01-01

    To report our experience using scenario approximation in a phenomenological study of nursing in Mexico. Experience report on scenario approximation to coexist with elderly in order to select the participants of a phenomenological study. During a four-month period in 2016, visits were carried out two groups of elderly individuals where several activities were carried out. Coexistence with the elderly throughout accompaniment in the groups' activities together with joint dialogue allowed selection of those who corresponded to the characteristics of the study objective. Scenario approximation is necessary in phenomenological studies, not only for creating empathy among the participants but also for the researchers to immerse themselves in the phenomenon under study, as shown by the first approaches of the researcher. Relatar la experiencia del acercamiento al escenario de un estudio fenomenológico en enfermería en México. Relato de experiencia sobre el acercamiento al escenario de estudio para convivir con adultos mayores con la finalidad de seleccionar a los participantes de un estudio fenomenológico. Se llevaron a cabo visitas durante el año 2016, en un periodo de cuatro meses a dos grupos de adultos mayores en donde se realizaron diversas actividades. La convivencia con los adultos mayores a través del acompañamiento en las actividades que realizaban en los grupos y el diálogo conjunto permitió seleccionar a aquellos que respondían a las características del objeto de estudio. Es necesaria la aproximación al escenario de estudios fenomenológicos, no sólo con la finalidad de ganar empatía de los participantes sino para sumergirse en el fenómeno de estudio, mismo que se va mostrando desde los primeros acercamientos del investigador.

  15. [Iatrogenic after spinal puncture technique. Prevalence study of headache and associated factors].

    PubMed

    Bauset-Navarro, José Luis; Sánchez-Ortuño, Isabel M; Gómez-Cárdenas, Claudia; Sanz-Monllor, Ainara; Cinesi-Gómez, César; Piñera-Salmerón, Pascual

    2014-03-01

    Objetivo. Establecer la prevalencia existente de cefalea tras practicar una puncion lumbar transdural y los factores de riesgo. Pacientes y metodos. Estudio observacional prospectivo de cohortes. Se reclutaron pacientes del Servicio de Urgencias, del Servicio de Neurologia y del Hospital de Dia. Se recogio la experiencia del facultativo, el numero de punciones, la variacion de plano, la postura del paciente, el anestesico local, el calibre y bisel de la aguja, los grados de inclinacion, la cantidad de liquido, la sobrecarga de fluidoterapia y la indicacion o no de reposo tras la puncion. Tras 48 horas, se establecio la aparicion o no de cefalea. Resultados. Muestra de 59 pacientes, 31 (52,5%) de ellos hombres. Edad media: 47 años; 32 (54,2%) procedentes de Urgencias, 18 (30,5%) de Neurologia y 9 (15,3%) del Hospital de Dia. Hubo 41 (69,5%) en decubito lateral y 7 (11,9%) en sedestacion. Todos con agujas biseladas, 21 (35,6%) del calibre 20 y 38 (64,4%) del calibre 22. Sin reposo estuvieron 8 (13,56%) pacientes y 18 (33,3%) sin sobrecarga de fluidos. Veintitres (38,98%) con cefalea pospuncion lumbar, 12 (52,2%) mujeres, con una edad media de 38,3 ± 16,4 años. La mediana de intensidad de la cefalea fue de 2,6. El tiempo medio de aparicion fue de siete horas. Sin diferencias para ninguno de los factores estudiados, salvo la tendencia observada de mayor incidencia de cefalea a menor edad. Conclusiones. La cefalea pospuncion lumbar en nuestra serie es elevada, sin diferencias segun el servicio donde se practica o la experiencia. Tampoco influye la cantidad de liquido extraido, la posicion del paciente, la indicacion de reposo o la sobrecarga de fluidos.

  16. Evaluation of methods to derive green-up dates based on daily NDVI satellite observations

    NASA Astrophysics Data System (ADS)

    Doktor, Daniel

    2010-05-01

    Bridging the gap between satellite derived green-up dates and in situ phenological observations has been the purpose of many studies over the last decades. Despite substantial advancements in satellite technology and data quality checks there is as yet no universally accepted method for extracting phenological metrics based on satellite derived vegetation indices. Dependent on the respective method derived green-up dates can vary up to serveral weeks using identical data sets. Consequently, it is difficult to compare various studies and to accurately determine an increased vegetation length due to changing temperature patterns as observed by ground phenological networks. Here, I compared how the characteristic NDVI increase over temperate deciduous forests in Germany in spring relates to respective budburst events observed on the ground. MODIS Terra daily surface reflectances with a 250 m resolution (2000-2008) were gathered to compute daily NDVI values. As ground truth, observations of the extensive phenological network of the German Weather Service were used. About 1500 observations per year and species (Beech, Oak and Birch) were available evenly distributed all over Germany. Two filtering methods were tested to reduce the noisy raw data. The first method only keeps NDVI values which are classified as ‚ideal global quality' and applies on those a temporal moving window where values are removed which differ more than 20% of the mean. The second method uses an adaptation of the BISE (Best Index Slope Extraction) algorithm. Subsequently, three functions were fitted to the selected observations: a simple linear interpolation, a sigmoidal function and a double logistic sigmoidal function allowing to approximate two temporally separated green-up signals. The green-up date was then determined at halfway between minimum and maximum (linear interpolation) or at the inflexion point of the sigmoidal curve. A number of global threshold values (NDVI 0.4,0.5,0.6) and

  17. Structural Preconditions of West Bohemia Earthquake Swarms

    NASA Astrophysics Data System (ADS)

    Novotný, M.; Špičák, A.; Weinlich, F. H.

    2013-07-01

    swarms. The sealed focal domains retain ascending magmatic fluids until their critical pressure and volumes accumulated cause rock micro-fractures perceived as single earthquake bursts. During a swarm period, the focal depths of these sequential events become shallower while their magnitudes grow. We assume that coalescence of the induced micro-fractures forms temporary permeability zones in the final swarm phase and the accumulated fluids release into the overburden via the adjacent fault systems. The fluid release usually occurs after the shallowest events with the strongest magnitudes ML > 3. The seasonal summer declines of hydrostatic pressure in the Cheb Basin aquifer system seem to facilitate and trigger the fluid escape as happened for the 2000, 2008, and 2011 earthquake swarms. The temporary fluid release, known as the valve-fault action, influences the surface aquifer systems in various manners. In particular, we found three quantities, the strain, mantle-derived 3He content in CO2 surface sources and ground water levels, which display a 3-5 months decline before and then a similar restoration after each peak earthquake during the swarm activities. The revealed structure features are particularly important since the main Nový Kostel earthquake swarm area is proposed as a site for the ICDP project, `Eger Rift Drilling'.

  18. Geological and Geochemical Criteria for the Estimation of the Area of The Lesser Hinggan for the Endogenous Gold Mineralization (The Far East, Russia)

    NASA Astrophysics Data System (ADS)

    Yurchenko, Yuriy

    2015-04-01

    The Area of the Lesser Hinggan in the middle of the XIX century has been known as one of the Gold areas of the Far East. Exploration of gold in different years were engaged by P.K. Yavorovskiy (1904), E.E. Anert (1928), G.V. Itsikson (1961), V.A. Buryak (1999, 2002, 2003), A.M. Zhirnov (1998, 2000, 2008), L.V. Eyrish (1960, 1964, 1995, 1999, 2002, 2008) and many others. But despite the abundance of factual materials in the problem of the gold metallogeny of the Lesser Hinggan are more aspects that still have not received a answer. Among them is the key issue about indigenous sources of the gold. First for the Lesser Hinggan area, structural-geochemical zoning at 1:200 000 scale was carried out based on the results of the precise analyses of over 2,600 soil and sediment stream samples. Three anomalous geochemical zones and nine anomalous geochemical clusters in their contours specialized for gold mineralization were revealed. Regional clarkes (fersms) for 19 chemical elements were calculated. Geological formations geochemically specialized for gold and their role in endogenous ore-forming processes were defined. Geochemical criteria for endogenous gold mineralization and its ore-formational affiliation were defined as well. Thus, from the geological and geochemical data, are the following signs of the gold mineralization of the Lesser Hinggan: 1. Some geological formations are geochemical specialized by the gold (carbon ("black") schists and ferruginous quartzite Vendian-Cambrian Hinggan series). They're considered as a source of the gold, involved in younger epigenetic processes of mobilization and redistribution of this element; 2. Contrasting geochemical anomalies of the gold and elements satellites in the secondary halos and stream sediments displayed in the contours of the geological formations of a wide age range - terrigenous-carbonate rocks of the Hinggan series, the Paleozoic granitoid massives, the Cretaceous volcanic fields ; 3. Samples of the native gold

  19. A calibration-free evapotranspiration mapping technique

    NASA Astrophysics Data System (ADS)

    Szilagyi, J.

    2010-12-01

    in Central-Europe over the 2000-2008 period, and in Nebraska in Central-North America for 2000-2009. The resulting monthly ET rates have been validated with eddy-covariance measurements at three sites in Hungary with other two sites in Nebraska together with Bowen-ratio station measurements at six additional locations in Nebraska. The vegetation cover of the sites varied greatly, from grass, to agricultural crop, to orchards and forests. On an annual and multi-year basis the ET estimates have also been validated with catchment water-balance data of five watersheds (spanning three magnitudes of spatial scale) in Hungary. On a monthly basis ET estimates typically give an R2 value of 0.8 - 0.9, with a minimum value of 0.73 and maximum of 0.95, and on an annual and multi-year basis a typical value of 0.7 - 0.8 with a minimum of 0 (for riparian forest sites with diminished inter-annual variability) and maximum of 0.91. The mean annual ET estimates remain well within 10% of the measured values.

  20. Space and time distribution of foci and source-mechanisms of West-Bohemia/Vogtland earthquake swarms - a tool for insight into their triggering mechanisms and driving forces

    NASA Astrophysics Data System (ADS)

    Horalek, Josef; Fischer, Tomas; Cermakova, Hana

    2013-04-01

    West Bohemia/Vogtland (border area between Czech Republic and Germany) belongs to the most active intraplate earthquake-swarm regions in Europe. Above, this area is characteristic by high activity of crustal fluids. Swarm earthquakes with magnitudes ML < 4.0 occur frequently in the area of about 3 000 km2, however, the Nový Kostel focal zone (NK), which shows a few tens of thousands events within the last twenty years, dominates the recent seismicity of the whole region. During last fifteen years there were four earthquake swarms in 1997, 2000, 2008 and 20011 (besides a few tens of microswarms) encompassing a fault plane of about 15 x 6 km. The swarms were located close to each other. Moreover, the 2000 (MLmax = 3.3) and 2008 (MLmax = 3.8) swarms were "twins", i.e. their hypocenters fall precisely on the same portion of the NK fault plane; and the 1997 (MLmax = 2.9) and 2011 (MLmax = 3.6) swarms also occurred on the same fault segment. However, the individual swarms differed considerably in their evolution, mainly in the rate of the seismic-moment release and foci migration. Source mechanisms (in the full moment-tensor description) and their time and space variations also show different patterns. All the 2000- and 2008-swarm events were pure shears, most of them showing the oblique normal faulting. Although source mechanisms of majority of the 2000- and 2008 events signify the faulting parallel to the main NK fault plane, there is a significant amount of events having different source mechanisms. We also found alteration of the source mechanisms with depths. The 1997 and 2011 swarms took place on two differently oriented fault segments thus two different source mechanisms occurred: the oblique-normal on the one segment and the oblique-thrust type on the other one. Moreover, source mechanisms of the oblique thrust events suggest combined sources (possessing significant non-DC components). This indicates complexity of both NK focal zone (where earthquake swarms have

  1. Space and time distribution of foci and source mechanisms of West-Bohemia/Vogtland earthquake swarms - a tool for understanding of their origin

    NASA Astrophysics Data System (ADS)

    Horálek, Josef; Čermáková, Hana; Fischer, Tomáš

    2014-05-01

    The origin of earthquake swarms remains still an enigma. The swarms typically accompany volcanic activity at the plate margins but also occur in intracontinental areas. West Bohemia-Vogtland (border area between Czech Republic and Germany) represents one of the most active intraplate earthquake-swarm regions in Europe. Above, this area is characteristic by high activity of crustal fluids. Swarm earthquakes occur persistently in the area of about 3 000 km2. However, the Novö Kostel focal zone (NK), which shows a few tens of thousands events within the last twenty years, dominates the recent seismicity of the whole region. There were swarms in 1997, 2000, 2008 and 20011 followed by reactivation in 2013, and a few tens of microswarms which forming a focal belt of about 15 x 6 km. We analyse geometry of the NK focal zone applying the double-difference method to seismicity in the period 1997 - 2013. The swarms are located close to each other in at depths from 6 to 13 km. The 2000 (MLmax = 3.3) and 2008 (MLmax = 3.8) swarms are 'twins' i.e. their hypocenters fall precisely on the same portion of the NK fault; similarly the 1997 (MLmax = 2.9), 2011 (MLmax = 3.6) and 2013 (MLmax = 2.4) swarms also occurred on the same fault segment. However, the individual swarms differ considerably in their evolution, mainly in the rate of the seismic-moment release and foci migration. Source mechanisms (in the full moment-tensor description) and their time and space variations also show different patterns. All the 2000- and 2008-swarm events are pure shears, signifying both oblique-normal and oblique-thrust faulting but the former prevails. We found a several families of source mechanisms, which fit well geometry of respective fault segments being determined on the basis of the event location: The 2000 and 2008 swarms activated the same portion of the NK fault, hence the source mechanisms are similar. The 1997 and 2011 swarms took place on two differently oriented fault segments, thus

  2. Earthquake statistics, spatiotemporal distribution of foci and source mechanisms as a key to understanding of causes leading to the West Bohemia/Vogtland earthquake swarms

    NASA Astrophysics Data System (ADS)

    Horalek, Josef; Jakoubkova, Hana

    2017-04-01

    The origin of earthquake swarms is still unclear. The swarms typically occur at the plate margins but also in intracontinental areas. West Bohemia-Vogtland represents one of the most active intraplate earthquake-swarm areas in Europe. It is characterised by a frequent reoccurrence of ML < 4.0 swarms and by high activity of crustal fluids. The Nový Kostel focal zone (NK) dominates the recent seismicity of the whole region. There were swarms in 1997, 2000, 2008 and 20011 followed by reactivation in 2013 which forming a focal belt of about 15 x 6 km, focal depths vary from 6 to 15 km. An exceptional non-swarm activity (mainshock-aftershock sequences) up to magnitudes ML = 4.5, stroke the region in May to August 2014, the events were also located in the NK swarm-focal belt. We analysed geometry of the NK focal zone applying the double-difference method to seismicity in the period 1997 - 2014. The swarms are located close to each other at depths between 6 and 13 km, the 2014 maishock-aftershock sequences among them. The 2000 and 2008 swarms were located on the same portion of the NK fault, similarly the swarms of 1997, 2011 and 2013 also occurred on the same fault segment. Other fault segment hosted three mainshock-aftershock sequences of 2014. The individual swarms differ considerably in their evolution, mainly in the rate of the seismic-moment release and foci migration. The frequency-magnitude distributions of all the swarms show bimodal-like character: the most events obey the b-value = 1.0 distribution, however, a group of the largest events ( ML > 2.8) depart significantly from it. Furthermore, we disclose that all the ML > 2.8 swarm events, which occurred in the given time span, are located in a few dense clusters. It implies that the most of seismic energy in the individual swarms has been released in step by step rupturing of one or a few asperities. The source mechanisms have been retrieved in the full moment-tensor description (MT). The mechanism patters of

  3. An assessment on the MODIS quality data over the Iberian Peninsula (Southern Europe)

    NASA Astrophysics Data System (ADS)

    Huesca, Margarita; Merino-de-Miguel, Silvia; Cicuéndez, Víctor; Litago, Javier; Palacios-Orueta, Alicia

    2014-05-01

    Satellite remote sensing may provide land surface processes observations at high temporal frequency over long periods of time. However, many influences have a bearing on the spectral properties which may be derived from multi-spectral data. The MODIS (Moderate Resolution Imaging Spectroradiometer) Land Science Team provides quality assessment (QA) data. QA is key information for the correct interpretation of remote sensing products since we need to discrimite between real changes on the Earth surface and satellite product artefacts (Roy et al., 2002). The present work focuses on evaluating the quality of the MOD09A1 (Surface Reflectance 8-Day L3 Global 500m) product over the Iberian Peninsula during the period 2000-2008. The quality was estimated in terms of identifying the most important noise sources that might distort the data as well as identifying the areas and seasons where they were dominant. The specific objectives were: (i) to select the most relevant QA parameters based on their frequency over the study area, (ii) to analyze the spatial distribution of the QA parameters and stratify the territory based on this information, and (iii) to analyze the temporal distribution of the QA parameters. The quality data founded within the MOD09A1 product provides information: (i) at the pixel level, (ii) per reflectance band and (iii) for the whole file. In particular, QA is stored in two different layers or bands, one related to each band and based on sensor characteristics and image acquisition (named 'Surface Reflectance Data' QA layer), and the other one related to each pixel and based on external conditions (named 'Surface Reflectance Data State' QA layer). The present work focuses only on this second one. The QA parameters were analyzed in terms of the number of dates where we found low quality pixels, and of the presence of long gaps (four or more consecutive low quality dates). The next step consisted of using the number of low quality dates and the number of

  4. Remotely sensed spatio-temporal trends of irrigation agriculture in northwestern India

    NASA Astrophysics Data System (ADS)

    Cela Diaz, F.; Siegfried, T. U.; Vasquez, V.; Pollard, B. S.; Temimi, M.; Narula, K. K.; Lall, U.

    2009-12-01

    Irrigated agricultural production plays a key role in covering the world’s food demand. Its importance will grow in the future given increasing population numbers and uncertain climate. Irrigation, however, has also a major impact on water resources, esp. in the drylands on the planet. For example, most of the large-scale problems of aquifer mining can be linked to groundwater-irrigated agriculture. South Asia is one of these regions of concern where roughly 40 percent of the total global groundwater irrigated area is located. In India, almost half of the total agricultural area is irrigated and it is estimated that groundwater irrigation in the country sustains 27 million ha. Esp. in the northwestern part of the country, water tables are falling at increasing rates that give rise to concern about the future viability of irrigation there. Since the majority of food grains in India are produced in that region, this development is a direct threat to the national food security with potentially global implications. We present a novel remote sensing approach to map the temporal development of irrigated agriculture at large spatial scales with high accuracy. We use time series data from the Moderate Resolution Imaging Spectroradiometer (MODIS) on NDVI and surface temperature as well as high-resolution precipitation data from the Indian Meteorological Department from 2000 - 2008 and ancillary data for our supervised classification approach. A cascade of classifiers was chosen to deal with the problem of obtaining labeled examples. A first stage classifier uses large regions of known irrigated and non-irrigated areas to learn a rough estimate of the multi-dimensional time series signature on variables of interest in non-irrigated areas. An estimate of the probability of non-irrigation is generated and passed to a second stage classifier along with the variables used to derive it. The second stage classifier is trained with a small dataset of very high quality estimates

  5. Carbon Fluxes in a Managed Landscape: Assessing the Drivers of Temporal and Spatial Variability in Flux Tower, MODIS and Forest Inventory Data of the Pacific Northwest

    NASA Astrophysics Data System (ADS)

    Wharton, S.; Bible, K.; Falk, M.; Paw U, K.

    2010-12-01

    This research focuses on the Wind Late Successional Reserve of Southern Washington where clear-cut logging over the past 100 years has created a fragmented landscape of coniferous forests that range in age from 0 to 500 years. In this study, we integrate several datasets to examine the environmental drivers of carbon exchange in this region across time and space. These sources include: (1) network of flux towers across a disturbance choronosequence, (2) MODIS Enhanced Vegetation Index, (3) aboveground net primary production (ANPP) from forest inventories, (4) and regional precipitation and air temperature measurements from the NOAA network of weather stations and PRISM reanalysis data. Net ecosystem exchange of carbon (NEE) has been measured at the Wind River Canopy Crane AmeriFlux site since 1998. The canopy crane is located in an old-growth forest composed of late seral Douglas-fir (Pseudotsuga menziesii) and western hemlock (Tsuga heterophylla). Two flux towers were erected in early seral stands to study the effects of silviculture on net ecosystem exchange. CO2 uptake at the old-growth stand is highest in the spring before bud break when air and soil temperatures and vapor pressure deficit are relatively low, and soil moisture and light levels are favorable for photosynthesis, while maximum CO2 uptake is observed two to three months later at the early seral stands and coincide with peak leaf area index. This CO2 pattern is driven by different water conserving strategies. A reduction in carbon exchange is observed at the old-growth forest when moisture becomes limiting and canopy conductance rates drop sharply after mid-morning in the summer. In contrast, inhibition in canopy conductance rates and CO2 exchange is not observed at the early seral stands until soil moisture levels become critically low at the very end of the summer. The regional MODIS data (200 km X 200 km area) from 2000-2008 show that annual variability in the Enhanced Vegetation Index (EVI) also

  6. Earthquake statistics, spatiotemporal distribution of foci and source mechanisms as a key to understanding of causes leading to the West Bohemia/Vogtland earthquake swarms

    NASA Astrophysics Data System (ADS)

    Horálek, Josef; Čermáková, Hana; Fischer, Tomáš

    2015-04-01

    The origin of earthquake swarms is still unclear. The swarms typically occur at the plate margins but also in intracontinental areas. West Bohemia-Vogtland represents one of the most active intraplate earthquake-swarm areas in Europe. It is characterised by a frequent reoccurrence of ML < 4.0 swarms and by high activity of crustal fluids. The Nový Kostel focal zone (NK) dominates the recent seismicity of the whole region. There were swarms in 1997, 2000, 2008 and 20011 followed by reactivation in 2013 which forming a focal belt of about 15 x 6 km, focal depths vary from 6 to 15 km. An exceptional non-swarm activity (mainshock-aftershock sequences) up to magnitudes ML = 4.5, stroke the region in May to August 2014, the events were also located in the NK swarm-focal belt. We analysed geometry of the NK focal zone applying the double-difference method to seismicity in the period 1997 - 2014. The swarms are located close to each other at depths between 6 and 13 km, the 2014 maishock-aftershock sequences among them. The 2000 and 2008 swarms were located on the same portion of the NK fault, similarly the swarms of 1997, 2011 and 2013 also occurred on the same fault segment. Other fault segment hosted three mainshock-aftershock sequences of 2014. The individual swarms differ considerably in their evolution, mainly in the rate of the seismic-moment release and foci migration. The frequency-magnitude distributions of all the swarms show bimodal-like character: the most events obey the b-value = 1.0 distribution, however, a group of the largest events (~ML > 2.8) depart significantly from it. Furthermore, we disclose that all the ML > 2.8 swarm events, which occurred in the given time span, are located in a few dense clusters. It implies that the most of seismic energy in the individual swarms has been released in step by step rupturing of one or a few asperities. The source mechanisms have been retrieved in the full moment-tensor description (MT). The mechanism patters of

  7. Ecosystems resilience to drought: indicators derived from time-series of Earth Observation data

    NASA Astrophysics Data System (ADS)

    Garcia, Monica; Fernández, Nestor; Delibes, Miguel

    2013-04-01

    recovery was characterized by (i) the duration of -effects (ii) resistance to change and (iii) autocorrelation of the time-series. Time series of 2000-2008 from the satellite MODIS and meteorological stations were used. Evapotranspiration was estimated using a surface energy balance contextual or triangle approach using EO data. Analyses were performed at time-steps from 1 month up to 1 year. Among the four ecosystems, wetlands were the most resilient with a faster rate of recovery from drought but at the same time greater transient responses. Perennial vegetation types showed more resistance to drought but higher persistence of effects into the following year, especially shrublands without access to groundwater. Drought effects in pine forests were minimum as they access groundwater during dry periods. Our results suggest that in a future context of higher rainfall extremes, the long-term success in the case of vegetation types with access to the water table might depend on their capability to balance groundwater extractions and rainfall recharge. In the vegetation types without access to the water table their success will depend on their recovery potential after a drought sequence of several years.

  8. The impact of climate and land use changes on water resources. The application of the integrated hydrological modelling system, IHMS (Invited)

    NASA Astrophysics Data System (ADS)

    Ragab, R.; Bromley, J.; Dörflinger, G.; Katsikides, S.; D'Agostino, D. R.; Lamaddalena, N.; Trisorio, G. L.; Montenegro, S. G.; Montenegro, A.

    2010-12-01

    DiCaSM model has been applied on Mimoso catchment in the Brazilian NE region. The model successfully simulated streamflows (2000 -2008) and forecasted a reduction of 27% to 71%, for ground water recharge, and 26% to 67%, for streamflow. Introducing castor beans would increase the groundwater recharge and streamflow, if the caatinga areas would be converted into castor beans. Changing an area of 1000 ha from caatinga to castor beans would increase the groundwater recharge by 46% and streamflow by 3%. If the same area of pasture is converted into castor beans, there would be an increase of groundwater recharge and streamflow by 24% and 5%, respectively. The examples suggest that IHMS is an effective tool for the authorities to help balance water demand and supply under the climate and land use changes.

  9. Correlation and toxicological inference of trace elements in tissues from stranded and free-ranging bottlenose dolphins (Tursiops truncatus).

    PubMed

    Stavros, Hui-Chen W; Stolen, Megan; Durden, Wendy Noke; McFee, Wayne; Bossart, Gregory D; Fair, Patricia A

    2011-03-01

    The significance of metal concentrations in marine mammals is not well understood and relating concentrations between stranded and free-ranging populations has been difficult. In order to predict liver concentrations in free-ranging dolphins, we examined concentrations of trace elements (Al, As, Ba, Be, Cd, Co, Cu, Fe, Li, Mn, Ni, Pb, Sb, Se, Sn, total Hg (THg), V, Zn) in skin and liver of stranded bottlenose dolphins (Tursiops truncatus) from the South Carolina (SC) coast and the Indian River Lagoon, Florida (FL) during 2000-2008. Significantly higher concentrations of Zn, Fe, Se, Al, Cu and THg were found in skin while liver exhibited significantly higher Cu, Fe, Mn and THg concentrations for both study sites. Mean skin concentrations of Cu and Mn were significantly higher in SC dolphins while higher concentrations of THg and V were found in FL dolphins. In addition, liver tissues in SC dolphins exhibited significantly higher As concentrations while higher Fe, Pb, Se, THg, and V levels were found in FL dolphins. Two elements (Cu and THg) showed significant age-related correlations with skin concentration while five elements (Cu, Se, THg, Zn and V) showed age-related correlations with liver concentrations. Geographic location influenced age-related accumulation of several trace elements and age-related accumulation of THg in hepatic tissue was observed for both sites to have the highest correlations (r² = 0.90SC; r² = 0.69FL). Mean THg concentration in liver was about 10 times higher in FL dolphins (330 μg g⁻¹ dw) than those samples from SC dolphins (34.3 μg g⁻¹ dw). The mean molar ratio of Hg to Se was 0.93 ± 0.32 and 1.08 ± 0.38 for SC and FL dolphins, respectively. However, the Hg:Se ratio varied with age as much lower ratios (0.2-0.4) were found in younger animals. Of the 18 measured elements, only THg was significantly correlated in skin and liver of stranded dolphins and skin of free-ranging dolphins from both sites suggesting that skin may be

  10. Seismic Tomography Reveals Breaking Crust and Lithosphere Beneath a Classic Orogen

    NASA Astrophysics Data System (ADS)

    Byrne, T. B.; Rau, R.; Kuo-Chen, H.; Lee, Y.; Ouimet, W. B.; Van Soest, M. C.; Huang, C.; Wu, F. T.

    2013-12-01

    erosion, or lower rock uplift rates along the range crest. We propose that the surfaces represent relict topography that formed prior to a recent acceleration in rock uplift rate, consistent with the presence of a propagating crustal-scale crack and slab breakoff. Taken together, these results raise questions about the notion of steady state topography and critically tapered wedges in Taiwan. Kuo-Chen, H., Wu, F., and Roecker, S. W., 2012, Three-dimensional P velocity structures of the lithosphere beneath Taiwan from the analysis of TAIGER and related seismic data sets: Journal Geophysical Research, v. 117, no. B06306. Ching, K.-E., Hsieh, M.-L., Johnson, K., Chen, K.-H., Rau, R.-J., and Yang, M., 2011, Modern vertical deformation rates and mountain building in Taiwan from precise leveling and continuous GPS observations, 2000-2008: Journal Geophysical Research, v. 116, no. B08406.

  11. Validation of Erosion 3D in Lower Saxony - Comparison between modelled soil erosion events and results of a long term monitoring project

    NASA Astrophysics Data System (ADS)

    Bug, Jan; Mosimann, Thomas

    2013-04-01

    obtain better results, the DEM needs a higher resolution, and soil and landuse parameters have to been optimized in tractor tracks and headlands (higher bulk density, less coverage). Other models like LINERO (Bug &Mosimann 2012) can help to get an overview over the location of erosion forms and the soil loss due to rill erosion. References: Bug J., & T. Mosimann (2012): Modellierung der linearen Bodenerosion. Entwicklung eines entscheidungsbasierten Modells zur flächenhaften Prognose der linearen Erosionsaktivität, Geosynthesis 15, Hannover, 105 S. Michael, A., Schmidt, J. & W. A. Schmidt (1996): EROSION 2D/3D - Ein Computermodell zur Simulation der Bodenerosion durch Wasser. Parameterkatalog Sachsen, Freiberg. Mosimann, T., Bug, J. Sanders, S. & F. Beisiegel (2009): Bodenerosionsdauerbeobachtung in Niedersachsen 2000-2008. Methodik, Erosionsgeschehen, Bodenabträge und Anwendung der Ergebnisse, Geosynthesis 14, Hannover, 101 S. Schmidt, J., & M. v. Werner (2000): Modeling sediment and heavy metal yields of drinking water reservoirs in the Osterzgebirge region of Saxony (Germany). In: Schmidt, J. (Ed.), Soil Erosion—Application of Physically Based Models. Springer, Berlin, Heidelberg, New York, pp. 93- 108.

  12. Channel Change and Bed-Material Transport in the Lower Chetco River, Oregon

    USGS Publications Warehouse

    Wallick, J. Rose; Anderson, Scott W.; Cannon, Charles; O'Connor, Jim E.

    2010-01-01

    The lower Chetco River is a wandering gravel-bed river flanked by abundant and large gravel bars formed of coarse bed-material sediment. Since the early twentieth century, the large gravel bars have been a source of commercial aggregate for which ongoing permitting and aquatic habitat concerns have motivated this assessment of historical channel change and sediment transport rates. Analysis of historical channel change and bed-material transport rates for the lower 18 kilometers shows that the upper reaches of the study area are primarily transport zones, with bar positions fixed by valley geometry and active bars mainly providing transient storage of bed material. Downstream reaches, especially near the confluence of the North Fork Chetco River, are zones of active sedimentation and channel migration. Multiple analyses, supported by direct measurements of bedload during winter 2008-09, indicate that since 1970 the mean annual flux of bed material into the study reach has been about 40,000-100,000 cubic meters per year. Downstream tributary input of bed-material sediment, probably averaging 5-30 percent of the influx coming into the study reach from upstream, is approximately balanced by bed-material attrition by abrasion. Probably little bed material leaves the lower river under natural conditions, with most net influx historically accumulating in wider and more dynamic reaches, especially near the North Fork Chetco River confluence, 8 kilometers upstream from the Pacific Ocean. The year-to-year flux, however, varies tremendously. Some years may have less than 3,000 cubic meters of bed material entering the study area; by contrast, some high-flow years, such as 1982 and 1997, likely have more than 150,000 cubic meters entering the reach. For comparison, the estimated annual volume of gravel extracted from the lower Chetco River for commercial aggregate during 2000-2008 has ranged from 32,000 to 90,000 cubic meters and averaged about 59,000 cubic meters per year

  13. Channel Change and Bed-Material Transport in the Lower Chetco River, Oregon

    USGS Publications Warehouse

    Wallick, J. Rose; Anderson, Scott W.; Cannon, Charles; O'Connor, Jim E.

    2009-01-01

    The lower Chetco River is a wandering gravel-bed river flanked by abundant and large gravel bars formed of coarse bed-material sediment. The large gravel bars have been a source of commercial aggregate since the early twentieth century for which ongoing permitting and aquatic habitat concerns have motivated this assessment of historical channel change and sediment transport rates. Analysis of historical channel change and bed-material transport rates for the lower 18 kilometers show that the upper reaches of the study area are primarily transport zones, with bar positions fixed by valley geometry and active bars mainly providing transient storage of bed material. Downstream reaches, especially near the confluence of the North Fork Chetco River, have been zones of active sedimentation and channel migration. Multiple analyses, supported by direct measurements of bedload during winter 2008-09, indicate that since 1970 the mean annual flux of bed material into the study reach has been about 40,000-100,000 cubic meters per year. Downstream tributary input of bed-material sediment, probably averaging 5-30 percent of the influx coming into the study reach from upstream, is approximately balanced by bed-material attrition by abrasion. Probably very little bed material leaves the lower river under natural conditions, with most of the net influx historically accumulating in wider and more dynamic reaches, especially near the North Fork Chetco River confluence, 8 kilometers upstream from the Pacific Ocean. The year-to-year flux, however, varies tremendously. Some years probably have less than 3,000 cubic meters of bed-material entering the study area; by contrast, some high-flow years, such as 1982 and 1997, likely have more than 150,000 cubic meters entering the reach. For comparison, the estimated annual volume of gravel extracted from the lower Chetco River for commercial aggregate during 2000-2008 has ranged from 32,000 to 90,000 cubic meters and averaged about 59

  14. Glacial recession in the Tropical Andes from the Little Ice Age: the case of Ampato Volcanic Complex (Southern Peru

    NASA Astrophysics Data System (ADS)

    Alcalá, J.; Palacios, D.; Zamorano, J. J.

    2010-03-01

    the Ampato volcanic complex (15º24´- 15º 51´ S, 71º 51´ - 73º W; 6.288 masl), one of the most important complexes of the northern sector of the CVZ. Photointerpretation of aerial photographs and teledetection through satellite images of Huayuray Valley (15º 41´ 14´´ S - 71º 51´ 53´´ W), located to the north of the complex, aided in accurately reconstructing the area occupied by the ice mass at different times (LIA, 1955, 2000 and 2008). Also the paleo-ELA (Equilibrium Line Altitude) and the ELA were calculated using the Accumulation Area (AA) method (Kaser and Osmaston, 2002; Osmaston, 2005) in a GIS. The ELA shows the relationship between climate and glacier mass balance (González Trueba, 2005). The data from Huayuray Valley show that the glaciers reached a minimum altitude of 5400 masl and covered an area of ~2.81 Km2 during the LIA. The paleo-ELA was located at ~5780 masl, ~120 m below the current ELA (~5900 m). Based on a vertical thermal gradient of 0.65ºC/100 m, the temperature during this event would have been about 0.7º C colder than present temperature in the Ampato volcanic complex. In 1955, Huayuray glacier covered ~2.45 km2, 12.8% less than in the LIA. In the same year, the glaciers in the Huayuray valley reached a minimum elevation of ~5660 masl and the ELA rose ~20 m, to 5800 masl. In only 45 years (1955 - 2000) the surface area of the ice was significantly reduced (~1 km2), i.e. 40.8%. The ELA continued to rise, until it reached 5890 masl in 2000. From 2000 - 2008, the Huayuray glacier was reduced to ~0.78 km2 and the ELA rised ~10 m to reach the 5900 masl These results from the CVZ confirm the dramatic recession of the glaciers in the tropical Andes during recent decades. They also suggest that if the rate of recession associated with the period 2000-2008 continues, glaciers in the Ampato volcanic complex will disappear in 10 years approximately. References González Trueba, J.J. (2005): La Pequeña Edad del Hielo en los Picos de

  15. [Integration of a software for hospital nutritional support prescription and the electronic medical record].

    PubMed

    Alfaro Martínez, José Joaquín; López Díaz, Mariano; Hernández López, Antonio; Gonzalvo Díaz, César; Botella Romero, Francisco

    2013-01-01

    Introducción: La prescripción y seguimiento de la nutrición parenteral es un acto médico que debe ser correctamente documentado y que precisa de una adecuada comunicación entre médicos, farmacéuticos y personal de enfermería. Dicha prescripción puede realizarse mediante órdenes y formularios en papel o con aplicaciones informáticas, en cuyo caso surge la dificultad de su integración con el resto de la informática hospitalaria. Presentamos la experiencia de nuestro centro en la integración de un programa informático de prescripción de nutrición hospitalaria con la historia clínica electrónica. Material y métodos: Con objeto de desarrollar una aplicación informática de prescripción de nutrición artificial se llevaron a cabo reuniones entre personal de la Unidad de Nutrición Clínica y el Servicio de Informática donde se establecieron las necesidades de los servicios implicados y las características que debía tener la aplicación. Descripción de la aplicación: El programa informático permite la prescripción de nutrición parenteral componente por componente o mediante plantillas prediseñadas, genera alertas en caso de valores extremos de componentes o posible incompatibilidad físico-química, importa y almacena los resultados de las analíti cas de los pacientes y escribe la composición de la fórmula de nutrición parenteral prescrita en la historia clínica electrónica, entre otras características. Discusión: Nuestra experiencia muestra que la colaboración entre los servicios clínicos y de Informática permite desarrollar aplicaciones hospitalarias adaptadas a la forma de trabajo de los equipos clínicos y que pueden integrarse con el resto de los programas informáticos del hospital.

  16. Community-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus in critically-ill patients: systematic review.

    PubMed

    Carballo, Nuria; De Antonio-Cuscó, Marta; Echeverría-Esnal, Daniel; Luque, Sonia; Salas, Esther; Grau, Santiago

    2017-03-01

    Introducción: La neumonía adquirida en la comunidad (NAC) está relacionada con unas tasas elevadas de morbi-mortalidad. A pesar de que Staphylococcus aureus resistente a meticilina (SARM) se ha relacionado frecuentemente con la neumonía nosocomial, algunos pacientes con NAC por este microorganismo revisten la suficiente gravedad como para precisar su ingreso en la UCI.Objetivos: Efectuar una revisión sistemática de la literatura sobre el tratamiento antibiótico de la NAC por SARM en pacientes críticos.Material y métodos: Se realizó una búsqueda de artículos sobre NAC por SARM en el paciente crítico. Se identificaron las publicaciones pertinentes en PUBMED, BestPractice database, UpTo-Date database y Cochrane Plus Library para artículos publicados en inglés desde diciembre del 2001 hasta abril del 2016. Resultados: Se encontraron 70 publicaciones, incluyendo 13 (18,8%) y excluyendo 57 (81,4%). Predominaron los estudios de cohortes con un total de 6 (20,7%), frente a una única publicación en forma de estudio transversal (3,5%). Conclusiones: La experiencia en el tratamiento de la NAC por SARM en pacientes que precisen ingreso en la UCI es muy limitada. La vancomicina o el linezolid parecen ser las terapias en las que se dispone de una mayor experiencia, aunque no existe ninguna recomendación específica al respecto. Puede ser útil la utilización de vías alternativas como la nebulizada, administración en perfusión continua o en asociación con otros antibióticos.

  17. A Voice and a Vote: The Advisory Board Experiences of Spanish-Speaking Latina Mothers

    PubMed Central

    DeCamp, Lisa Ross; Gregory, Emily; Polk, Sarah; Chrismer, Marilyn Camacho; Giusti, Flor; Thompson, Darcy A.; Sibinga, Erica

    2016-01-01

    Latino children experience disparities in health care access and quality. Family advisory groups for clinics and hospitals may be one way to address disparities. We implemented and sustained an advisory board whose parent participants were exclusively limited-English proficient Latina mothers. As part of the board evaluation, we conducted semistructured individual interviews with parent participants during initial participation and after the final board meeting of the year. Members were satisfied with their board participation in both initial and follow-up interviews. They reported that board membership was an important way to improve clinic services and a unique opportunity for Latinos in the community. Experiences of discrimination and marginalization in health care settings were a theme across interviews. Members reported board membership countered these negative experiences. An advisory board including Spanish-speaking parents is an opportunity to engage vulnerable populations, which may result in broader impact on health care disparities. Los niños latinos experimentan disparidad en el acceso y calidad del cuidado de salud. Grupos de familias asesoras para clínicas y hospitales pueden ser una forma de hacer frente a las disparidades. Nosotros implementamos y sostuvimos un consejo asesor cuyos participantes fueron exclusivamente madres latinas con dominio limitado del inglés. Como parte de la evaluación del consejo, condujimos entrevistas semi-estructuradas individuales con las madres participantes durante la participación inicial y después de la última reunión del año del consejo. Los miembros estaban satisfechas con su participación en el consejo en ambas entrevistas, la inicial y la de seguimiento. Ellas reportaron que ser miembros del consejo era una forma importante para mejorar los servicios de la clínica y una oportunidad única para los latinos en la comunidad. Las experiencias de discriminación y marginalización en las instalaciones de

  18. [Influenza-like illness. Therapeutic experience in family medicine].

    PubMed

    Muñoz-Cortés, Gerardo; García-Zavala, Guadalupe Ulises; Estrada-Andrade, María Elena

    2013-01-01

    Introducción: la influenza es una enfermedad respiratoria muy contagiosa. Se debe iniciar el tratamiento antiviral en las primeras 48 horas para evitar la neumonía. El objetivo de este informe es describir la experiencia en el tratamiento de la enfermedad tipo influenza en una unidad de medicina familiar. Métodos: estudio descriptivo de pacientes que acudieron a urgencias con enfermedad tipo influenza (fiebre de 38 °C, cefalea y tos, acompañadas de otro síntoma) y que fueron contactados por vía telefónica. Los datos se expresan en media ± desviación estándar. Resultados: de 537 consultas por infecciones respiratorias agudas, 1.3 % reunió los criterios de enfermedad tipo influenza; 85.7 % era del sexo masculino. El promedio de la edad fue de 18 ± 24.21 años. La atención inicial ocurrió a las 19.14 horas después de que se iniciaron los síntomas. Todos los pacientes recibieron oseltamivir y zanamivir; 14.3 % presentó neumonía. El 100 % se restableció. No hubo enfermedades concomitantes. Conclusiones: existe un protocolo para el manejo de la enfermedad tipo influenza que hace posible el diagnóstico y el tratamiento oportunos de los pacientes.

  19. [80 years of soial service in medicine].

    PubMed

    Hace 80 años, la Escuela de Medicina de la Universidad Nacional, en voz de su director, Gustavo Baz Prada, hizo una propuesta que pronto se convirtió en realidad y finalmente en norma, la que desde entonces se conoce como SS. Esta iniciativa se vio como una manera para que los estudiantes de medicina del último año retribuyeran a la sociedad una parte de lo que esta invirtió en su educación, consolidaran su formación mediante la exposición a las realidades de todos los días en los medios más necesitados, se pusieran a prueba sobre sus verdaderas capacidades para atender pacientes y participaran en la solución de un problema de atención sanitaria que en ese entonces era mucho más apremiante que ahora. Unos años después, los recién egresados de otras licenciaturas (pasantes) también fueron incorporados a esta estrategia y, al fin, se reconoció formalmente como una responsabilidad de las instituciones educativas. Las aportaciones del SS a la salud de las personas y a la formación de los médicos han sido incuestionables, y la experiencia humana que ha representado para quienes lo han vivido ha dejado marcas indelebles.

  20. La Resonancia J/$\\psi$ y Sus Implicaciones Para La Masa Del W

    SciTech Connect

    Sanchez-Hernandez, Alberto

    1995-01-01

    Es un placer agradecer a mi asesor el doctor Heriberto Castilla Valdez por brindarme sus conocimientos, experiencia y paciencia en el desarrollo de esta tesis; tambien quiero agradecer al profesor H.E. Fisk, por su apoyo econemico en mi estancia en Fermilab. De igual forma agradezco a los doctores Arturo Fernandez Telles, Miguel Angel Perez Angen y Rebeca Juarez Wisozka quienes me introdujeron al campo de la fisica experimental de altas energfas. Agradezco tambien a Maribel Rios Cruz, Ruben Flores Mendieta, Juan Morales Corona, Fabiola Vazquez Valencia, Salvador Carrillo Moreno y Cecilia Uribe Estrada por su amistad y compaiierismo durante el desarrollo de mi maestria. Un especial agradecimiento a Ian Adam y Kina Denisenko por su valiosa ayuda, comentarios y discusiones durante mi estancia en Fermilab. Por ultimo quisiera agradecer a mis profesores, amigos y familiares quienes siempre me apoyaron y alentaron y al Consejo N acional de Ciencia y Tecnologfa asf como al Departamento de Fisica de Cinvestav por su apoyo econemlco.

  1. Modeling extreme wave heights from laboratory experiments with the nonlinear Schrödinger equation

    NASA Astrophysics Data System (ADS)

    Zhang, H. D.; Guedes Soares, C.; Cherneva, Z.; Onorato, M.

    2014-04-01

    Spatial variation of nonlinear wave groups with different initial envelope shapes is theoretically studied first, confirming that the simplest nonlinear theoretical model is capable of describing the evolution of propagating wave packets in deep water. Moreover, three groups of laboratory experiments run in the wave basin of CEHIPAR (Canal de Experiencias Hidrodinámicas de El Pardo, known also as El Pardo Model Basin) was founded in 1928 by the Spanish Navy. are systematically compared with the numerical simulations of the nonlinear Schrödinger equation. Although a little overestimation is detected, especially in the set of experiments characterized by higher initial wave steepness, the numerical simulation still displays a high degree of agreement with the laboratory experiments. Therefore, the nonlinear Schrödinger equation catches the essential characteristics of the extreme waves and provides an important physical insight into their generation. The modulation instability, resulting from the quasi-resonant four-wave interaction in a unidirectional sea state, can be indicated by the coefficient of kurtosis, which shows an appreciable correlation with the extreme wave height and hence is used in the modified Edgeworth-Rayleigh distribution. Finally, some statistical properties on the maximum wave heights in different sea states have been related with the initial Benjamin-Feir index.

  2. [National consensus on the ketogenic diet].

    PubMed

    Armeno, Marisa; Caraballo, Roberto; Vaccarezza, María; Alberti, M Julia; Ríos, Viviana; Galicchio, Santiago; de Grandis, Elizabeth S; Mestre, Graciela; Escobal, Nidia; Matarrese, Pablo; Viollaz, Rocío; Agostinho, Ariela; Díez, Cecilia; Cresta, Araceli; Cabrera, Analía; Blanco, Virginia; Ferrero, Hilario; Gambarini, Victoria; Sosa, Patricia; Bouquet, Cecilia; Caramuta, Luciana; Guisande, Silvina; Gamboni, Beatriz; Hassan, Amal; Pesce, Laura; Argumedo, Laura; Dlugoszewski, Corina; DeMartini, Martha G; Panico, Luis

    2014-09-01

    Introduccion. La epilepsia es una enfermedad cronica que afecta al 0,5-1% de la poblacion, mayormente de inicio durante la infancia. Un tercio de los pacientes evoluciona hacia una forma refractaria al tratamiento con farmacos antiepilepticos, lo que plantea al equipo de salud un desafio terapeutico. La dieta cetogenica (DC) es un tratamiento no farmacologico efectivo utilizado como un metodo alternativo para el tratamiento de la epilepsia refractaria. Objetivos. Es necesario establecer directrices para utilizar la DC adecuadamente y asi expandir su conocimiento y utilizacion en paises hispanoparlantes. El Comite Nacional de Dieta Cetogenica, dependiente de la Sociedad Argentina de Neurologia Infantil, elaboro este consenso para estandarizar el uso de la DC basandose en la bibliografia publicada y la experiencia clinica. El grupo esta formado por neuropediatras, medicos nutricionistas y licenciadas en nutricion de cinco provincias de Argentina pertenecientes a 10 centros que aplican la DC como tratamiento de la epilepsia refractaria. Desarrollo. Se exponen temas tales como la seleccion del paciente, el asesoramiento a la familia antes del tratamiento, las interacciones de la DC con la medicacion anticonvulsionante, los suplementos, el control de efectos adversos y la retirada de dicha dieta. Conclusiones. La DC es un tratamiento util para los pacientes pediatricos con epilepsia intratable. Es fundamental la educacion y colaboracion del paciente y la familia. El tratamiento debe llevarlo a cabo un equipo interdisciplinar experimentado, siguiendo un protocolo. La formacion de un grupo nacional interdisciplinar, y la publicacion de este consenso, ofrece la posibilidad de orientar a nuevos centros en su implantacion.

  3. Como Lo Hago Yo: Lipomas Medulares

    PubMed Central

    Portillo, Santiago

    2014-01-01

    Basados en la experiencia de 82 casos; en 5% se observaron anomalías pélvicas asociadas. En los menores de 3 años el motivo de consulta (85%) fue la tumoración. En los mayores de 3 años (42%) tenía problemas neurológicos. Solo el 24% preocupados por la tumoración. El objetivo de la cirugía es desanclar la médula y no remover la totalidad del lipoma. El lipoma de filum es el que es mas simple para operar. Aún cuando la escuela francesa propone operar solamente cuando hay síntomas favorezco cirugía preventiva. Favorezco una segunda cirugía si hay signos de anclaje postoperatorio, aún cuando observamos empeoramiento postoperatorio motor en 2.5% de los operados y urológico a largo plazo en 6% de los operados. PMID:24791218

  4. [Prevalence and differentiating aspects related to gender with regard to the bullying phenomenon in poor countries].

    PubMed

    Romera Félix, Eva M; Del Rey Alamillo, Rosario; Ortega Ruiz, Rosario

    2011-11-01

    There is a large body of scientific knowledge about school violence and bullying in Europe and some other regions of the so-called developed world. However, improvement is scarce in poor and developing regions, as in the case of Latin America and, in particular, Nicaragua. The goal of this work was to determine the prevalence of the bullying phenomenon in Nicaraguan primary schools, to analyze the eventual relationships between the different forms of violence used by the students and to explore, in relation to these aspects, the similarities and differences between boys and girls. For this purpose, we surveyed 3042 pupils of primary school (50.3% girls) using the "Cuestionario sobre Convivencia, Violencia y Experiencias de Riesgo" (COVER, in English, Questionnaire about Living Together, Violence and Risk Experiences). We found that the level of involvement in bullying is significantly higher than in developed countries, that boys are more involved than girls in verbal, physical and psychological bullying, and that there are no differences with regard to social exclusion. The results are discussed, comparing them with studies conducted in different countries but with similar methodologies.

  5. [Using Objective Structured Clinical Examination (OSCE) across different levels of pediatric training].

    PubMed

    Di Lalla, Sandra; Manjarin, Mercedes; Torres, Fernando; Ossorio, María Fabiana; Wainsztein, Raquel; Ferrero, Fernando

    2014-01-01

    Antecedentes:Evaluar competencias profesionales es objetivo principal de todo programa de capacitación; el examen clínico objetivo estructurado (ECOE) es una herramienta útil para explorarlas. Objetivo:Describimos la implementación del ECOE en tres instancias de enseñanza de la pediatría (carrera de especialista, módulo pediatría del internado anual rotatorio, materia pediatría en el grado). Métodos: En relación con situaciones y patologías frecuentes en pediatría, se evaluaron conocimiento aplicado, juicio clínico y habilidad comunicacional. Resultados: En el posgrado el ECOE se aplica desde hace 8 años, examinando 330 alumnos, con 60%-82% de aprobación. En el Internado Anual Rotatorio el ECOE se emplea desde hace 2 años, examinando 12 alumnos, con 84% de aprobación. En el grado el ECOE se empleó sólo en una oportunidad, examinando 15 alumnos, con 93,4% de aprobación. Conclusión:En nuestra experiencia, a pesar de desafíos logísticos, la implementación del ECOE fue factible en distintas instancias de enseñanza de la pediatría.

  6. [Update of the Gleason system and other prognostic pathological data in prostate cancer: Tumor load.

    PubMed

    García-González, Ricardo; García-Navas, Ricardo; Montáns-Araújo, José

    2016-12-01

    Desde que D. F. Gleason creara su sistema en 1966 (1 ) y que él mismo modificó en 1974 (2), su método ha sido universalmente aceptado y recomendado por la OMS (3)como factor pronóstico del carcinoma prostático (CaP). Pero, la generalización de la prueba del PSA a partir de 1979 (4), del desarrollo de la TRUS (5) y de la "biopty-gun" para la toma de biopsias en sextantes en los años 80 (6), y sus posteriores modificaciones, son hechos que han cambiado paulatinamente la postura ante el CaP y, con la experiencia adquirida, algunas de las reglas iniciales de Gleason han evolucionado. Aunque se publicaron varios estudios que proponían cambios en el sistema (7), solo los de la ISUP de 2005 (8), han tenido trascendencia real. En ellos se reconsideran algunos de los criterios para identificar aquellos tumores con un patrón histolgico de alto grado (patrón 4 o 5), redefiniendo estos patrones del sistema Gleason.

  7. [Multicentric hyaline vascular Castleman's disease. A POEMS type variant].

    PubMed

    Gracia-Ramos, Abraham Edgar; Cruz-Domínguez, María del Pilar; Vera-Lastra, Olga Lidia

    2013-01-01

    Introducción: la enfermedad de Castleman es un trastorno linfoproliferativo atípico en el que pueden existir manifestaciones compatibles con síndrome POEMS. Caso clínico: hombre de 53 años de edad con antecedente de diabetes mellitus tipo 2, hipotiroidismo y enfermedad de Addison. Se iniciaron parestesias y debilidad en las extremidades y, posteriormente, disnea, endurecimiento cutáneo, fenómeno de Raynaud y pérdida de peso. Se identificó taquipnea, hiperpigmentación cutánea generalizada y extremidades con endurecimiento cutáneo, debilidad muscular, hipoestesia e hiporreflexia; así como hiperprolactinemia, testosterona baja, hipotiroidismo y enfermedad de Addison; los anticuerpos antinucleares y antiScl-70 fueron negativos. Los potenciales evocados somatosensoriales indicaron neuropatía periférica y la electromiografía, olineuropatía axonal severa. Radiografía torácica: infiltrado reticular bilateral y ensanchamiento mediastinal. Electrocardiograma: hipertensión arterial pulmonar moderada. Tomografía toracoabdominal: ganglios axilares, mediastinales y retroperitoneales. Con la biopsia se identificó enfermedad de Castleman multicéntrica hialina vascular. El paciente recibió rituximab. Conclusiones: si bien la experiencia con el rituximab aún es limitada, en el caso descrito se observó buena respuesta.

  8. Factor VIII delivery devices in haemophilia A. Barriers and drivers for treatment adherence.

    PubMed

    Fernández-Arias, Isabel; Kim, Hae Kyung

    2016-11-01

    Introducción y objetivo: Recabar la experiencia de pacientes con hemofilia A con sus dispositivos de reconstitucion de factor de coagulacion, barreras para la adherencia y determinar sus preferencias, presentando una nueva jeringa de doble camara (JDC). Método: Investigacion transversal mediante encuesta dirigida y sesion de prueba de la JDC. Resultados: Participaron 74 pacientes, el 50% en tratamiento con profilaxis, y 7 anos (mediana) con su tratamiento habitual (RIC 17,25). En la encuesta, la JDC recibio la mayor puntuacion (75/100, p < 0,001) y la mayor probabilidad de uso en profilaxis (p < 0,001). En la sesion practica (n = 29), el 62,1% prefirio la JDC y necesitaron de mediana 43 segundos (24,5-82) para la preparacion, vs. 4 minutos (1-15) con el tratamiento habitual (p < 0,001). La opinion favorable del medico respecto a la profilaxis resulto muy influyente en la actitud de los participantes hacia la adherencia (OR = 1,324, IC 95% = 1,040-1,685, p = 0,023). Conclusiones: La JDC fue el dispositivo preferido y se mostro con probabilidad de favorecer la profilaxis.

  9. [Gender and work: the experience of providers of health services to indigenous women from Guerrero y Oaxaca].

    PubMed

    Amaya-Castellanos, Claudia Isabel; Pelcastre-Villafuerte, Blanca; Márquez-Serrano, Margarita; Juárez-Ramírez, Clara

    2012-03-01

    The scope of this paper was to identify the role of gender for women as workers, through the perception and discourse of health service providers at the 'Health Centers for Indigenous Women' ("Casas de Salud de las Mujeres Indígenas") in Ometepec, Guerrero and Matías Romero, Oaxaca, Mexico. It is a qualitative study, based on a secondary analysis of the interviews conducted as part of the "Rescatando la experiencia de la Casa de la Mujer Indígena: sistematización y evaluación del proceso" project. A strong sense of the value of work and a strong commitment towards the community were identified. Guilt appears as the result of tension between work outside the home and the responsibilities as mothers and wives. The possibility of helping other women is a source of gratification that dissipates these conflicts; prestige and recognition are added to the benefits of their role. The labor experience of female workers in the "Casas de Salud de las Mujeres Indígenas" of Matías Romero, Oaxaca and Ometepec, Guerrero, described in this paper, reveals that it has very specific characteristics, which are difficult to replicate in other regions of the country. In future studies it is necessary to consider the different contexts of vulnerability.

  10. [Nurses' perception, experience and knowledge of palliative care in intensive care units].

    PubMed

    Piedrafita-Susín, A B; Yoldi-Arzoz, E; Sánchez-Fernández, M; Zuazua-Ros, E; Vázquez-Calatayud, M

    2015-01-01

    Adequate provision of palliative care by nursing in intensive care units is essential to facilitate a "good death" to critically ill patients. To determine the perceptions, experiences and knowledge of intensive care nurses in caring for terminal patients. A literature review was conducted on the bases of Pubmed, Cinahl and PsicINFO data using as search terms: cuidados paliativos, UCI, percepciones, experiencias, conocimientos y enfermería and their alternatives in English (palliative care, ICU, perceptions, experiences, knowledge and nursing), and combined with AND and OR Boolean. Also, 3 journals in intensive care were reviewed. Twenty seven articles for review were selected, most of them qualitative studies (n=16). After analysis of the literature it has been identified that even though nurses perceive the need to respect the dignity of the patient, to provide care aimed to comfort and to encourage the inclusion of the family in patient care, there is a lack of knowledge of the end of life care in intensive care units' nurses. This review reveals that to achieve quality care at the end of life, is necessary to encourage the training of nurses in palliative care and foster their emotional support, to conduct an effective multidisciplinary work and the inclusion of nurses in decision making. Copyright © 2014 Elsevier España, S.L.U. y SEEIUC. All rights reserved.

  11. [Neuropsychotherapy in brain injury rehabilitation].

    PubMed

    García-Molina, Alberto; Roig-Rovira, Teresa; Enseñat-Cantallops, Antònia; Sánchez-Carrión, Rocío

    2014-02-01

    Introduccion. Las personas que han sufrido lesiones cerebrales pueden experimentar un amplio abanico de alteraciones cognitivas, conductuales y emocionales. No obstante, la rehabilitacion neuropsicologica acostumbra a centrarse, de manera casi exclusiva, en los deficits cognitivos y presta escasa atencion a los retos emocionales asociados al impacto psicologico de la lesion. En esta faceta mas personal del daño cerebral es donde la neuropsicoterapia puede ser de gran utilidad para facilitar el proceso de aceptacion y adaptacion despues de una lesion neurologica. Desarrollo. En el presente articulo se describen los aspectos teoricos y conceptuales de la psicoterapia orientada a personas con daño cerebral, implicaciones de los deficits cognitivos en la practica de la neuropsicoterapia y evidencias sobre su efectividad. Conclusiones. En el pasado se considero que la neuropsicoterapia tenia escasa utilidad en la rehabilitacion del daño cerebral. Hoy en dia, cada vez son mas los profesionales que reconocen su importancia en el abordaje del sufrimiento psicologico/emocional asociado al daño cerebral. El objetivo de la rehabilitacion neuropsicologica no es unicamente promover la recuperacion de las funciones cerebrales alteradas, sino tambien mejorar la capacidad funcional del individuo, tratar con sus experiencias de perdida y ayudarle a encontrar, de nuevo, sentido a la vida.

  12. [Musical hallucinations: perpetual music].

    PubMed

    Zabalza-Estévez, Ramón J

    2014-03-01

    Introduccion. Las alucinaciones musicales son un tipo de alucinacion auditiva prevalente en la poblacion no psiquiatrica, pero escasamente comunicada en la bibliografia neurologica. Ocurren con mayor frecuencia en la poblacion anciana, del sexo femenino y con perdida de audicion, pero su fisiopatologia esta por desentrañar. Casos clinicos. Se presentan seis casos (cinco mujeres y un hombre) de alucinaciones musicales diagnosticados en una consulta de neurologia general en un lapso de tiempo de cinco años. En cinco de ellos concurria la hipoacusia en mayor o menor grado y uno estaba desencadenado por la pentoxifilina. En su mayoria, el contenido musical de las alucinaciones provenia de experiencias musicales vividas en la infancia y juventud. En los casos sometidos a tratamiento farmacologico la respuesta fue pobre; sin embargo, una vez explicada a los pacientes la benignidad del cuadro y su desvinculacion con patologia psicotica, el grado de aceptacion del sintoma fue bueno. Conclusiones. Las alucinaciones musicales son una patologia fronteriza entre la neurologia, la otorrinolaringologia y la psiquiatria poco conocida, que, con frecuencia, se vincula erroneamente a la enfermedad mental. Es fundamental explicar a pacientes y familiares el caracter no necesariamente psiquiatrico de este sintoma, asi como conocer la potencialidad que tienen algunos farmacos de uso comun para generarlo.

  13. [Neurological maturation retardation].

    PubMed

    Campos-Castelló, Jaime

    2013-09-06

    Introduccion. Los primeros años de vida, esencialmente los primeros tres, estan presididos por una serie de hechos anatomofuncionales que expresan el progresivo enriquecimiento de la conducta a traves del proceso de maduracion neurologica, expresado como el alcanzar en cada etapa del desarrollo el maximo nivel funcional a traves del aprendizaje. Desarrollo. A partir de la experiencia personal, se abordan los principales aspectos conceptuales que definen la maduracion neurologica tanto en los aspectos de la normalidad, es decir, sus limites, como sus desviaciones patologicas, precisando limites conceptuales del llamado retraso madurativo. Se analizan los conceptos de 'niño de riesgo', y su control neuroevolutivo y factores de pronostico. Conclusiones. El fin ultimo y primordial de todos los estudios longitudinales es la deteccion precoz de todas las anomalias neurologicas –incluido el retraso madurativo– que permita un tratamiento precoz, curativo o paliativo, evitando generar 'falsos positivos' y, si la patologia neurologica queda definida como residual, establecer la ayuda al paciente y su entorno familiar para que ambos se adapten adecuadamente a esta situacion.

  14. [Anti-NMDA receptor encephalitis: two paediatric cases].

    PubMed

    González-Toro, M Cristina; Jadraque-Rodríguez, Rocío; Sempere-Pérez, Ángela; Martínez-Pastor, Pedro; Jover-Cerdá, Jenaro; Gómez-Gosálvez, Francisco

    2013-12-01

    Introduccion. La encefalitis asociada a anticuerpos antirreceptores de N-metil-D-aspartato (NMDA) es una patologia neurologica autoinmune documentada en la poblacion pediatrica de manera creciente en los ultimos años. Se presentan dos casos de nuestra experiencia con clinica similar. Casos clinicos. Caso 1: niña de 5 años que inicia un cuadro de convulsiones y alteracion de conciencia, asociando trastornos del movimiento y regresion de habilidades previamente adquiridas que evoluciona a autismo. Caso 2: niña de 13 años que presenta hemiparesia izquierda, movimientos anomalos, trastorno de conducta y disautonomia. En ambos casos se obtienen anticuerpos antirreceptores de NMDA positivos en el liquido cefalorraquideo y se diagnostican de encefalitis antirreceptor de NMDA. En el primer caso se inicia el tratamiento con perfusion intravenosa de corticoides e inmunoglobulinas y es necesario asociar rituximab. En el segundo, corticoides e inmunoglobulinas. La evolucion fue favorable en ambas pacientes, con una leve alteracion del lenguaje como secuela en el primer caso y una recaida en el segundo caso, con resolucion completa. Conclusion. La encefalitis antirreceptor de NMDA es un trastorno tratable y es importante el diagnostico y tratamiento precoz, ya que mejora el pronostico y disminuye las recaidas.

  15. [The mind-brain problem (II): about consciousness].

    PubMed

    Tirapu-Ustarroz, J; Goni-Saez, F

    2016-08-16

    Introduccion. La conciencia es el resultado de una serie de procesos neurobiologicos en el cerebro y a su vez es un rasgo del nivel de su complejidad. En realidad, el estar y el ser consciente nos situan ante lo que Chalmers ha denominado el 'problema blando' y el 'problema duro' de la conciencia. El primero hace referencia a aspectos como la vigilia, la atencion o el conocimiento, y el segundo a conceptos tan complejos como autoconciencia, 'yo neural' o cognicion social. En este sentido se puede afirmar que el concepto de conciencia como algo unitario plantea problemas de acercamiento a una realidad sumamente compleja. Desarrollo. Planteamos los principales modelos que desde una perspectiva neurocientifica han abordado el tema de la conciencia. Por un lado, los modelos de experiencia consciente de Crick, Edelman y Tononi, y Llinas, y por otro, los modelos y las bases neuronales de la autoconciencia de autores como Damasio (conciencia central y extendida), Tulving (conciencia autonoetica, noetica y cronestesia), el problema de los qualia (Dennett, Popper, Ramachandran) y el modelo de los cognitos (Fuster). Conclusiones. Todos los estimulos que recibimos del mundo externo y de nuestro mundo interno son convertidos y tratados por el cerebro para integrarlos y que formen parte de nuestra identidad. Desde la percepcion de un perro y reconocerlo como tal hasta la comprension de la propia conciencia responden al funcionamiento de estructuras cerebrales, neuronas y sinapsis. Ahora bien, los procesos mas complejos de la conciencia, como la autoconciencia o la empatia, son probablemente procesos emergentes del cerebro.

  16. Salud mental en desastres naturales: estrategias interventivas con adultos mayores en sectores rurales de Chile.

    PubMed

    Osorio-Parraguez, Paulina; Espinoza, Adriana

    2016-06-01

    En el presente artículo se da a conocer una estrategia de intervención llevada a cabo con adultos mayores en la comuna de Paredones, sexta región de Chile, con posterioridad al terremoto y tsunami del 27 de febrero 2010 en Chile, en el contexto de una investigación sobre fortalezas y vulnerabilidades desplegadas por este grupo etario, con posterioridad a un desastre natural. Se presenta una descripción del desarrollo metodológico de la intervención y de los sustentos teóricos y conceptuales en los que se basa. Como resultado de este proceso, se propone una estrategia que trabaje a través de la identificación de las propias experiencias y fortalezas de los sujetos. De tal forma se minimizan los efectos negativos de los determinantes sociales de la salud (como la edad y el lugar de residencia) en contexto de crisis; permitiendo a los adultos mayores fortalecer sus recursos individuales y colectivos, en pro de su bienestar psicosocial.

  17. [Surgical adrenal approaches: learned experiences].

    PubMed

    Bravo-Lázaro, Santos; Hernandis-Villalba, Juan; Meroño-Carbajosa, Emilio; Navío-Perales, Juan; Marzal-Felici, Vicente

    2014-01-01

    Antecedentes: la cirugía laparoscópica se ha implantado como técnica quirúrgica de elección en la patología quirúrgica suprarrenal. No obstante, el resto de los abordajes quirúrgicos sigue teniendo su indicación. Objetivos: exponer nuestra experiencia en los diferentes abordajes quirúrgicos y las lecciones aprendidas. Material y métodos: estudio retrospectivo y descriptivo de 40 pacientes, análisis de datos demográficos y resultados de los diferentes accesos. Resultados: se intervinieron 32 pacientes por padecer enfermedades benignas, y 8 por afecciones malignas. La vía de laparotomía se utilizó de entrada en 7 casos de malignidad, y en 4 pacientes con tumores benignos de gran tamaño. La vía de Young se utilizó en 4. La vía laparoscópica se indicó de entrada en 25 pacientes, y 7 requirieron la conversión a laparotomía. La tasa de conversión fue de 28%. Conclusiones: la técnica laparoscópica es la de elección en la mayoría de los pacientes. Es preciso establecer indicaciones adecuadas, sin olvidar los abordajes abiertos.

  18. [Relationships between language disorders and socio-emotional competence].

    PubMed

    Baixauli-Fortea, Inmaculada; Roselló-Miranda, Belén; Colomer-Diago, Carla

    2015-02-25

    Introduccion. Existe una comorbilidad elevada entre los trastornos del lenguaje y los problemas conductuales, emocionales y sociales. Objetivo. Revisar la bibliografia existente sobre las dificultades sociales y emocionales de los niños con trastorno especifico del lenguaje desde una perspectiva evolutiva. Desarrollo. En la infancia temprana, los resultados acerca de este tipo de dificultades en niños con un retraso del lenguaje no son concluyentes. Sin embargo, desde el periodo de educacion infantil, la investigacion advierte de una mayor ocurrencia de alteraciones en el area social y emocional. Los estudios longitudinales que han permitido determinar el ajuste psicosocial en la adolescencia indican un mayor riesgo de presentar experiencias de victimizacion y bullying o de desarrollar ansiedad y depresion a largo plazo, aunque algunos trabajos ofrecen una panoramica mas alentadora. Conclusiones. La afectacion de la comprension y del componente pragmatico del lenguaje es un predictor importante en la manifestacion de alteraciones socioemocionales. En los trastornos mixtos comprensivos-expresivos, una dificultad de procesamiento general podria justificar, al menos parcialmente, esta asociacion. A su vez, es probable que limitaciones en el desarrollo de la cognicion social contribuyan a explicar, en cierta medida, las dificultades de las personas con trastornos pragmaticos, si bien no existe una consistencia en la investigacion en este sentido.

  19. [The role of the prefrontal cortex in the sensory problems of children with autism spectrum disorder and its involvement in social aspects].

    PubMed

    Martínez-Sanchis, Sonia

    2015-02-25

    Introduccion. En las personas con trastornos del espectro autista (TEA), las percepciones sensoriales aberrantes podrian ser tan caracteristicas y disruptivas como la presencia de anomalias en la comunicacion e interaccion social, asi como de intereses restringidos y repetitivos. La mayoria presenta trastornos de la modulacion sensorial (hiper o hiporresponsividad) en varios canales sensoriales. Ademas, muestra un deficit en la integracion de la informacion procedente de varios sistemas sensoriales (por ejemplo, auditivo y visual). Todo ello agravaria los sintomas nucleares relacionados con la comunicacion y aumentaria la aparicion de problemas conductuales. Objetivo. Revisar la evidencia experimental que aborda el papel de la corteza prefrontal en las experiencias sensoriales inusuales en los TEA y su implicacion en los aspectos sociales. Hay evidencia de hipoactivacion y disfuncion en redes neurales, que incluyen la corteza prefrontal y participan en la cognicion social, como la red por defecto y el sistema de neuronas espejo en niños con TEA. Conclusiones. Los problemas sensoriomotores a edad temprana suponen una disrupcion de la organizacion y regulacion no solo de la percepcion y la accion, sino tambien del lenguaje, el pensamiento, la emocion e incluso la memoria.

  20. [Clinical experience with omalizumab in patients with severe asthma. Real-world data].

    PubMed

    Vargas-Correa, Jorge Bernardo; Bracamonte-Peraza, Raúl; Espinosa-Morales, Sylvia Marcela; Vázquez-Nava, Francisco

    2016-01-01

    Antecedentes: El omalizumab es un anticuerpo monoclonal que se prescribe en esquema de adición por pasos para el tratamiento del asma severa. Objetivos: Informar la experiencia en pacientes con asma severa a quienes se aplicó omalizumab conforme a las guías internaciones, en un contexto de datos de mundo real. Métodos: Estudio retrospectivo, clínico, observacional, abierto, analítico y transversal a partir de datos de la vida real. Se utilizó el esquema de Control del Asma de GINA 2006 para evaluar a los pacientes y con un cuestionario se calificaron las características del paciente, efectividad, seguridad y tolerancia al omalizumab. Resultados: Se estudiaron 48 pacientes, 34 mujeres y 14 hombres, con edad promedio de 39 años. La duración promedio de la enfermedad fue de 26 años. La concentración sérica promedio de la IgE fue de 522 UI. Al inicio del tratamiento, todos los pacientes estaban sin control del asma; al final, en 69% se obtuvo control del asma, 19% estaba parcialmente controlado y 12% sin modificaciones. Los cambios se observaron en promedio a los siete meses. Conclusión: El omalizumab es efectivo y seguro para tratar el asma severa cuando se aplica conforme las guías internacionales para el manejo del asma bronquial.

  1. [National consensus on the modified Atkins diet].

    PubMed

    Vaccarezza, María; Agustinho, Ariela; Alberti, M Julia; Argumedo, Laura; Armeno, Marisa; Blanco, Virginia; Bouquet, Cecilia; Cabrera, Analía; Caraballo, Roberto; Caramuta, Luciana; Cresta, Araceli; de Grandis, Elizabeth S; DeMartini, Martha G; Diez, Cecilia; Diz, Mariana; Dlugoszewski, Corina; Escobal, Nidia; Ferrero, Hilario; Galicchio, Santiago; Gambarini, Victoria; Gamboni, Beatriz; Gonzalez, Lara; Guisande, Silvina; Hassan, Amal; Matarrese, Pablo; Mestre, Graciela; Pesce, Laura; Rios, Viviana; Semprino, Marcos; Sosa, Patricia; Toma, Marisol; Viollaz, Rocío; Panico, Luis

    2016-04-16

    Introduccion. La epilepsia es una enfermedad cronica que afecta al 0,5-1% de la poblacion, y un tercio de los pacientes evoluciona hacia una forma refractaria a los farmacos antiepilepticos. Dentro de los tratamientos no farmacologicos disponibles, la dieta cetogenica Atkins modificada es un tratamiento efectivo utilizado desde 2003 como otra alternativa en niños y adultos con epilepsia refractaria. Desarrollo. El Comite Nacional de Dieta Cetogenica, dependiente de la Sociedad Argentina de Neurologia Infantil, elaboro este consenso sobre dieta Atkins modificada basandose en una revision de la bibliografia y en su experiencia clinica. Este consenso explica los distintos aspectos que hay que tener en cuenta sobre la dieta Atkins modificada, eleccion de pacientes, forma de implementacion, diversos controles y efectos adversos. A diferencia de la dieta cetogenica clasica, se inicia sin ayuno ni hospitalizacion, y no hay restriccion proteica, calorica o hidrica, por lo que mejora la palatabilidad y, consecuentemente, la tolerabilidad. Conclusiones. La dieta Atkins modificada es un tratamiento util para pacientes con epilepsia intratable. La publicacion de este consenso ofrece la posibilidad de orientar a nuevos centros en su implementacion.

  2. Seismological study of the structure and the evolution of Piton de la Fournaise plumbing system from the April 2007 major eruption

    NASA Astrophysics Data System (ADS)

    Massin, F.; Ferrazzini, V.; Bachèlery, P.; Nercessian, A.; Duputel, Z.; Staudacher, T.

    2009-04-01

    The study of the seismic activity associated to the eruptions of 2007 that led to the collapse of the Dolomieu crater on April 5, reveals the link between seismicity and magma transfer at the Piton de la Fournaise (PdF). Three eruptive phases occurred on February 18, March 30 and April 2 2007, illustrating the three different types of eruption defined at PdF volcano. The February 18 eruption was a summit eruption located along an east-west fissure inside the Dolomieu crater while March 30 was a proximal eruption, on the south-east flank of the central cone. An intense seismic crisis has been recorded between March 31 and April 2 preceding the distal eruption of April 2. This eruption was situated 8 km away from the central cone on the south-east rift-zone of PdF volcano. The Dolomieu crater collapsed from April 5 to 6, during a paroxysmal phase of seismic and eruptive activity. We use cross-correlation of seismic waveforms techniques to improve earthquake locations and determine best-constrained focal mechanisms. This technique gives a view of the seismicity organization in terms of pre-existing and newborn structures and highlights the pre-existing structures associated to Dolomieu crater collapse. From a dataset of 2580 triggered records, with 714 hand picked earthquakes, our cross correlation procedure allowed us to pick automatically 1625 events for relocation. 633 out of 1625 events were relocated and the composite focal mechanism of 154 clusters have been determined. The clustering results underline the change in seismicity before and after the March eruption. The pre-eruptive seismicity of February and March eruptions forms time extended clusters and reactivates several clusters found preceding other lateral eruptions of the 2000-2008 period. The seismicity preceding the Dolomieu collapse takes place in numerous but time limited clusters. The April eruption has been prepared two months earlier, but the collapse of Dolomieu crater is associated with a

  3. State - Level Regulation's Effectiveness in Addressing Global Climate Change and Promoting Solar Energy Deployment

    NASA Astrophysics Data System (ADS)

    Peterman, Carla Joy

    Paper 1, Local Solutions to Global Problems: Climate Change Policies and Regulatory Jurisdiction, considers the efficacy of various types of environmental regulations when they are applied locally to pollutants whose damages extend beyond the jurisdiction of the local regulators. Local regulations of a global pollutant may be ineffective if producers and consumers can avoid them by transacting outside the reach of the local regulator. In many cases, this may involve the physical relocation of the economic activity, a problem often referred to as "leakage." This paper highlights another way in which local policies can be circumvented: through the shuffling of who buys from whom. The paper maintains that the problems of reshuffling are exacerbated when the options for compliance with the regulations are more flexible. Numerical analyses is presented demonstrating that several proposed policies to limit greenhouse gas emissions from the California electricity sector may have very little effect on carbon emissions if they are applied only within that state. Paper 1 concludes that although local subsidies for energy efficiency, renewable electricity, and transportation biofuels constitute attempts to pick technology winners, they may be the only mechanisms that local jurisdictions, acting alone, have at their disposal to address climate change. Paper 2, Pass-Through of Solar PV Incentives to Consumers: The Early Years of California's Solar PV Incentives, examines the pass through of incentives to California solar PV system owners. The full post-subsidy price consumers pay for solar power is a key metric of the success of solar PV incentive programs and of overall PV market performance. This study examines the early years of California's most recent wave of distributed solar PV incentives (2000-2008) to determine the pass-through of incentives. Examination of this period is both intellectually and pragmatically important due to the high level of incentives provided and

  4. The experience of bedaquiline implementation at a decentralised clinic in South Africa.

    PubMed

    Cariem, R; Cox, V; de Azevedo, V; Hughes, J; Mohr, E; Durán, L Triviño; Ndjeka, N; Furin, J

    2016-09-01

    centro de atención Nolungile. En general, los miembros del personal del centro refirieron una experiencia positiva con la administración del medicamento. Las dificultades surgieron en gran parte con respecto a aspectos logísticos del suministro y la administración del medicamento. Es posible iniciar un tratamiento eficaz con BDQ en condiciones ambulatorias, y represente una experiencia positiva para los pacientes y los profesionales de salud.

  5. Report of the procedure of voluntary interruption of pregnancy at a university hospital in Uruguay.

    PubMed

    Bentancor, Ana; Hernández, Ana Laura; Godoy, Yamile; Dapueto, Juan J

    2016-07-04

    datos sociodemográficos de las pacientes concordaron con los reportados a nivel nacional: 81,0% de las pacientes que consultaron era mayores de 19 años; 6,2% decidieron continuar con el embarazo; solo 70,0% concurrieron al control posterior y recibieron asesoramiento sobre anticoncepción. Al año de su implementación, en Uruguay, podemos evaluar la experiencia como positiva desde el punto de vista de la salud de las mujeres. Nuestra experiencia como equipo de salud mental en el Hospital de Clínicas, inserto dentro del equipo multidisciplinario de interrupción voluntaria del embarazo, se encuentra en pleno proceso de evaluación y reformulación de prácticas.

  6. [Self-reported experience in patients treated with Hepatitis C direct acting antivirals].

    PubMed

    Cañamares Orbis, Irene; Saez de la Fuente, Javier; Escobar Rodriguez, Ismael; Esteban Alba, Concepción; Such Díaz, Ana; Escobar Rodríguez, Ismael

    2016-11-01

    Introducción y objetivo: Conocer y analizar la experiencia autorreferida del tratamiento de los pacientes VHC que iniciaron tratamiento con agentes antivirales directos (AAD), a tiempo real, de forma proactiva e integrada en el proceso asistencial de atención farmacéutica. Material y métodos: Estudio observacional y transversal desarrollado entre abril (inicio del Plan Estratégico Nacional) y diciembre de 2015 en la Consulta Externa del Servicio de Farmacia. Se utilizó como herramienta un cuestionario prospectivo cumplimentado por los pacientes donde se recogieron variables relacionadas con la calidad de vida vinculadas con la salud (CVRS), adherencia, efectos adversos (EA), satisfacción con el tratamiento, y valoración y utilidad del programa formativo implementado por el Servicio de Farmacia. Se realizó un análisis descriptivo de todas las variables incluidas en el estudio y se analizó la influencia de las diferentes variables en el grado de adherencia y CVRS. El análisis de las diferencias entre los dos grupos se realizó mediante el test de chi cuadrado y el cálculo de las OR con un modelo de regresión logística simple. Se utilizó el programa SPSS® versión 20, y se estableció una significación estadística para valores de p < 0,05. Resultados: Se recogieron155 encuestas de las 226 enviadas, tasa de respuesta del 68,6%.En referencia a la CVRS (valoración del estado físico y emocional), un 38,7% de los pacientes refieren que su estado físico y emocional es mucho mejor desde el inicio del tratamiento. La presencia de EA y una peor información global de su enfermedad se asoció con un peor estado físico y emocional (p < 0,05). La adherencia reportada fue del 84,5% y el tratamiento fue valorado como muy bueno o bueno por el 87% de los pacientes. Un 52,9% de los pacientes no tuvieron efectos adversos relacionados con la medicación y el proceso formativo realizado por el farmacéutico especialista en la primera consulta fue valorado por el 96

  7. The experience of bedaquiline implementation at a decentralised clinic in South Africa

    PubMed Central

    Cariem, R.; Cox, V.; de Azevedo, V.; Hughes, J.; Mohr, E.; Durán, L. Triviño; Ndjeka, N.

    2016-01-01

    centro de atención Nolungile. En general, los miembros del personal del centro refirieron una experiencia positiva con la administración del medicamento. Las dificultades surgieron en gran parte con respecto a aspectos logísticos del suministro y la administración del medicamento. Es posible iniciar un tratamiento eficaz con BDQ en condiciones ambulatorias, y represente una experiencia positiva para los pacientes y los profesionales de salud. PMID:27695682

  8. [Physical activity by pregnant women and its influence on maternal and foetal parameters; a systematic review].

    PubMed

    Aguilar Cordero, M J; Sánchez López, A M; Rodríguez Blanque, R; Noack Segovia, J P; Pozo Cano, M D; López-Contreras, G; Mur Villar, N

    2014-10-01

    Introducción: Las múltiples ventajas que aporta a la salud la práctica de una actividad física de forma continuada son conocidas. Aunque es importante en todas las etapas de la vida, cuando llega la gestación aparecen algunas dudas sobre la conveniencia de realizar ejercicio físico, así como del tipo de actividad, de su frecuencia, intensidad y duración. Objetivo: Analizar los principales estudios sobre la influencia de la actividad física sobre los parámetros materno- fetales. Método: Revisión sistemática de programas de actividad física destinados a las mujeres embarazadas y sus resultados durante el embarazo, el parto y el postparto. Se identificaron 45 artículos a través de la búsqueda automatizada en las bases de datos PUBMED, Scopus y Google Scholar; se llevó a cabo entre los meses de octubre de 2013 y marzo de 2014. Para seleccionar los artículos fue preciso considerar la utilidad y la relevancia del tema estudiado y la credibilidad o experiencia de los autores en la temática. Se tuvo en cuenta la validez interna y externa de cada uno de los artículos revisados. Conclusiones: Los resultados de la revisión ponen de manifiesto la importancia de la actividad física durante el periodo gestacional y se constata que la información disponible en la actualidad puede servir de referente inicial para continuar profundizando en los resultados que sobre la salud materno fetal tiene la práctica de actividad física en el medio acuático.

  9. Classification of structural lesions in magnetic resonance imaging. Surgical implications in drug-resistant epilepsy patients.

    PubMed

    Torres, C V; Pastor, J; Garcia-Navarrete, E; Pulido-Rivas, P; Sola, R G

    2015-09-16

    Introduccion. En la seleccion quirurgica del paciente con epilepsia farmacorresistente, el papel de la resonancia magnetica (RM) no se ha cuantificado hasta el momento. Presentamos la experiencia en nuestra Unidad de Cirugia de la Epilepsia. Pacientes y metodos. Se estudiaron retrospectivamente los pacientes intervenidos por epilepsia farmacorresistente. Distinguimos dos periodos: 1990-2000 (RM de 0,5 T) y 2001-2008 (RM de 1,5 T). La RM preoperatoria se clasifico en tres grupos: RM con lesion quirurgica (LQ), RM orientativa (LO) y RM normal (NL). Tambien se efectuo una clasificacion anatomopatologica similar. Se correlacionaron las distintas clasificaciones y los resultados quirurgicos. Resultados. Periodo 1990-2000: 151 pacientes. El 70% quedo en las clases de Engel I o II. Segun la RM, los resultados fueron: LQ, 87%; LO, 65%; y NL, 57%. Las diferencias fueron estadisticamente significativas. Periodo 2001-2008: 114 pacientes. El 89% quedo en las clases de Engel I o II. Segun la RM: LQ, 100%; LO, 90%; y NL, 81%. Las diferencias fueron estadisticamente significativas. Los pacientes con epilepsia del lobulo temporal y extratemporal con LQ tuvieron un 100% de control; con LO, el 95% con epilepsia del lobulo temporal y el 43% con estado epileptico; en aquellos pacientes sin lesion (NL), el 88% con epilepsia del lobulo temporal se controlo frente al 50% con estado epileptico. Conclusiones. La RM es una herramienta eficaz en la seleccion de candidatos quirurgicos en la epilepsia. La LQ asocia muy buen pronostico. En la epilepsia del lobulo temporal se pueden obtener muy buenos resultados (80-90% de control) a pesar de una RM normal. En el estado epileptico, las LO pueden tener peor resultado que la NL en la RM.

  10. Astronomy at School: Measurements of the Earth-Moon Distance. (Spanish Title: Astronomía en la Escuela: Medición de la Distancia Tierra-Luna.) Astronomia na Escola: Medida da Distância Terra-Lua

    NASA Astrophysics Data System (ADS)

    Paolantonio, Santiago; Pintado, Olga I.

    2006-12-01

    The aim of this project is to approach High School students to Science. We propose to measure the Earth-Moon distance using the parallax. The observation and measurements techniques and all the calculations needed are described in this paper. The results obtained in a test experience realized during 2003 are presented. This test shows that this is a feasible project and also shows which things needed to be improved. Se plantea la propuesta de un proyecto educativo dirigido al Nivel Medio de enseñanza, consistente en la determinación de la distancia Tierra - Luna por paralaje. Se describen las técnicas de observación, mediciones y cálculos. Se proporcionan a continuación los resultados obtenidos en la experiencia piloto realizada en el 2003, la que permitió comprobar la factibilidad de llevar a cabo la propuesta, así como perfeccionar los diferentes aspectos involucrados en la misma. Propomos neste trabalho um projeto educativo dirigido ao Ensino Médio que consiste na determinação da distância Terra-Lua pelo efeito da paralaxe. As técnicas de observação, medidas e cálculos auxiliares são descritos, e os resultados obtidos numa experiência-teste realizada no ano de 2003 apresentados. Este último teste permitiu comprovar a viabilidade de execução da proposta e aperfeiçoar diversos aspectos da mesma.

  11. [Dapagliflozin, a novel oral antidiabetic with an uncertain future].

    PubMed

    Escudero Vilaplana, Belén; Almodóvar Carretón, María José; Herrero Hernández, Silvia

    2014-11-03

    Objetivo: La diabetes mellitus tipo 2 (DM2) es uno de los principales problemas sociosanitarios a nivel mundial, para la que existen multitud de tratamientos. Recientemente, se ha aprobado el primer farmaco de una nueva familia de antidiabeticos orales (ADO): la dapagliflozina. Nuestro objetivo es revisar la evidencia cientifica disponible sobre la dapagliflozina, con el fin de analizar su eficacia, seguridad y coste y poder estimar su papel en la farmacoterapia actual de la DM2. Métodos: La eficacia y seguridad de la dapagliflozina se analizaron mediante una evaluacion de la evidencia cientifica. El coste de los diferentes ADO se calculo en base a sus dosis diarias definidas (DDD) y al precio de venta del laboratorio. Resultados: Se identificaron 7 ensayos clinicos aleatorizados: 2 en monoterapia (840 pacientes) y 5 en terapia combinada con otros antidiabeticos (3184 pacientes). En los 7 ensayos, la dapagliflozina redujo la concentracion de HbA1c; en todos se comparo con placebo, salvo en un estudio en terapia combinada que se comparo frente a farmaco activo (glipizida). Entre los efectos adversos mas frecuentes se detectaron infecciones genitourinarias e hipotension, aunque se debe prestar especial atencion al incremento del cancer de vejiga. Junto con los inhibidores de la DPP-4, la dapagliflozina es uno de los ADO de mayor coste (coste anual de DDD=729,3 euros). Conclusiones: La dapagliflozina no aporta ventajas respecto a la farmacoterapia de la DM2 ya existente. Su falta de experiencia de uso, la ausencia de importantes beneficios clinicos y su elevado coste hacen necesario restringir su utilizacion.

  12. Identificación de Intervenciones para el Desarrollo Positivo de la Juventud

    PubMed Central

    Sardiñas, Lili M.; Padilla, Viviana; Aponte, Mari; Boscio, Ana Morales; Pedrogo, Coralee Pérez; Santiago, Betzaida; Morales, Ángela Pérez; Dávila, Paloma Torres; Cesáreo, Marizaida Sánchez

    2017-01-01

    Resumen En el mundo hay más personas en la etapa de la juventud que en cualquier otra etapa del desarrollo. La juventud en Puerto Rico enfrenta muchas situaciones que inciden en su desarrollo y preparación para la adultez. Por lo tanto, es imperante identificar intervenciones para el desarrollo positivo de la juventud que han demostrado ser basadas en la evidencia. Además, a partir de dicha identificación, desarrollar prácticas que ayuden a los jóvenes a desarrollarse para prevenir situaciones adversas, promover experiencias positivas y propiciar que los niños y jóvenes estén involucrados y comprometidos. Se identificaron 147 intervenciones a través de una revisión tradicional de la literatura científica estadounidense. Los resultados reflejan que las intervenciones atienden la reducción de factores de riesgo y el incremento de factores de protección. Sin embargo, ninguna intervención propicia que los niños y jóvenes estén involucrados y comprometidos con su desarrollo óptimo y con sus comunidades. No obstante, todas brindan herramientas que podrían ser de utilidad para fomentar dichas prácticas en el contexto de Puerto Rico. De las 147 intervenciones identificadas seis están diseñadas para la población puertorriqueña residente en la Isla. Con el propósito de hacer la información accesible a los profesionales y la comunidad se expandió la colección del Archivo de Programas y Prácticas Basadas en Evidencia para la Prevención. PMID:28919943

  13. [Spinal tuberculosis: experience in a third level medical facility in Puebla, Mexico].

    PubMed

    Medina-Peñasco, Rolando Joshua; Rosas-Ramírez, Martha Imelda; Barragán-Hervella, Rodolfo Gregorio; Alvarado-Ortega, Ivan; López-Cázares, Gerardo; Montiel-Jarquín, Álvaro José; Romero-Figueroa, María Socorro

    2017-01-01

    Introducción: La tuberculosis de la columna (TBC) es una enfermedad infecciosa grave, ocasionada por la migración de la bacteria Mycobacterium tuberculosis hacia la columna vertebral. El conocimiento de esta enfermedad es prioritario para el médico no familiar y familiar. Presentamos la experiencia en pacientes con TBC de un hospital del tercer nivel en Puebla, México. Métodos: estudio descriptivo. De enero a diciembre de 2014 recolectamos expedientes de pacientes con TBC. Las variables fueron edad, género, tiempo de estancia intrahospitalaria, enfermedades asociadas, sintomatología, métodos diagnósticos, segmento de la columna vertebral afectado, tipo de tratamiento empleado y complicaciones. Se usó estadística descriptiva, medidas de tendencia central y de dispersión. Resultados: fueron 14 pacientes (71.4% hombres); la edad promedio fue 60.29 ± 16.54 años (33-93), la estancia intrahospitalaria promedio fue de 18.93 ± 9.32 días (4-34). El segmento afectado fue el dorsal en seis pacientes (42.85%) y el lumbar en ocho (57.15%). Hubo enfermedades asociadas en nueve pacientes (64.28%). Todos los pacientes recibieron tratamiento médico. Se realizaron 11 procedimientos quirúrgicos a cinco pacientes (35.7%). Las complicaciones se presentaron en dos pacientes (14.3%). Conclusiones: La TBC debe ser manejada tempranamente para evitar complicaciones graves. La atención con el primer nivel de atención médica se debe coordinar y debemos apegarnos a lineamientos nacionales e internacionales de tratamiento.

  14. [Wolf-Hirschhorn syndrome. A series of 27 patients: their epidemiological and clinical characteristics. The current situation of the patients and the opinions of their caregivers regarding the diagnostic process].

    PubMed

    Blanco-Lago, Raquel; Málaga, Ignacio; García-Peñas, Juan José; García-Ron, Adrián

    2013-07-16

    Introduccion. El sindrome de Wolf-Hirschhorn (SWH) es una cromosomopatia producida por una delecion en la region distal del brazo corto del cromosoma 4. Se caracteriza por la presencia de un fenotipo peculiar, retraso en el crecimiento, retraso del desarrollo psicomotor y epilepsia. Objetivos. Describir las caracteristicas de una serie de niños con SWH, incluido el tiempo medio empleado para el diagnostico, y valorar la opinion de las familias sobre el proceso diagnostico. Pacientes y metodos. Se contacto con la Asociacion Nacional de SWH y, a traves de ella, con 29 familias afectadas. Se recogio informacion sobre la clinica del niño y la opinion sobre el proceso diagnostico, y se solicitaron informes medicos que confirmaran la informacion facilitada. Constituida una base de datos de pacientes, se procedio a su analisis estadistico. Resultados. Se obtuvo informacion de 27 familias. Los pacientes presentan una edad media actual de 6,94 ± 6,37 años. La edad media de diagnostico fue de 14,34 meses. Existe retraso del crecimiento intrauterino en el 92,6% de los embarazos. Un 92,6% de los pacientes presenta epilepsia, el 44,4% de ellos en monoterapia. Existe retraso del desarrollo psicomotor/cognitivo en todos los pacientes. Camina sin ayuda el 33%. Los padres califican con una nota media de 7,25 ± 2,17 el trato ofrecido por los facultativos y de 6,29 ± 2,11 la informacion recibida. Conclusiones. No se han encontrado referencias a la edad media de diagnostico para el SWH. En nuestra muestra, existen variaciones importantes en este aspecto, posiblemente condicionadas por el fenotipo del caso y la experiencia del medico. Las caracteristicas clinicas son similares a las esperadas. El grado de dependencia estimado es alto y la calidad de la informacion recibida por la familia, baja.

  15. [Response to everolimus in patients with giant cell astrocytoma associated to tuberous sclerosis complex].

    PubMed

    Mateos-González, M Elena; López-Laso, Eduardo; Vicente-Rueda, Josefina; Camino-León, Rafael; Fernández-Ramos, Joaquín A; Baena-Gómez, M Auxiliadora; Peña-Rosa, M José

    2014-12-01

    Introduccion. Los astrocitomas subependimarios de celulas gigantes (SEGA) se presentan en el 5-20% de los pacientes con complejo esclerosis tuberosa (CET) y son los tumores cerebrales mas comunes en el CET. Son tumores benignos, de estirpe glioneural, que se desarrollan fundamentalmente en las primeras dos decadas de la vida, en general cercanos al foramen de Monro, y pueden ocasionar hidrocefalia e hipertension intracraneal. Constituyen la principal causa de muerte en el CET. Recientemente, los inhibidores mTOR han demostrado ser una alternativa terapeutica a la reseccion quirurgica. Objetivo. Describir nuestra experiencia con everolimus para el tratamiento de pacientes con SEGA y CET. Pacientes y metodos. Estudio prospectivo de la respuesta de los pacientes con CET y al menos un SEGA en crecimiento. Resultados. Recibieron tratamiento tres mujeres y tres varones con una edad media de 12,3 años. Un paciente habia sido previamente intervenido quirurgicamente por SEGA con hidrocefalia. El diametro maximo medio del SEGA al inicio del tratamiento era de 15,3 mm (rango: 11,3-24,8 mm). Se inicio tratamiento con everolimus, 2,5 mg/dia por via oral en pacientes con superficie corporal < 1,2 m2 y 5 mg/dia en pacientes con superficie corporal > 1,2 m2. Dos pacientes presentaron hipertrigliceridemia; uno, anorexia; otro, un afta; y una paciente, amenorrea. La reduccion media del volumen del SEGA a los tres meses de tratamiento fue del 46%, y la reduccion se mantuvo estable en controles posteriores (6-25 meses). Conclusiones. El tratamiento con everolimus disminuye el tamaño de los SEGA asociados a CET con un perfil de seguridad adecuado, y constituye una alternativa a la cirugia en casos seleccionados.

  16. [Epilepsy surgery in children with focal cortical dysplasias].

    PubMed

    Villarejo-Ortega, Francisco J; Álvarez-Linera Prado, Juan; Pérez-Jiménez, M Ángeles

    2013-09-06

    Introduccion. Las displasias corticales focales (DCF) son la primera etiologia de cirugia de la epilepsia pediatrica. La evaluacion prequirurgica en DCF a menudo es compleja, ya que son lesiones que pueden ser altamente epileptogenas y, a la vez, conservar funcion neurologica, y no visualizarse en la resonancia magnetica. El exito de la cirugia depende, en gran medida, de la adecuada identificacion de la lesion y de la posibilidad de realizar una reseccion completa del tejido displasico. En este trabajo se revisa la bibliografia relacionada con el tema, en relacion con la experiencia de los autores. Desarrollo. Se revisan algunos avances relacionados con la evaluacion prequirurgica y el abordaje neuroquirurgico de la epilepsia en niños con DCF; se comentan los resultados de las series quirurgicas en relacion con las clasificaciones de DCF y los factores de pronostico posquirurgico; se describen algunos fenotipos anatomoelectroclinicos distintivos en niños con DCF y su abordaje quirurgico; y se comentan brevemente los actuales retos y el futuro del tratamiento quirurgico de la epilepsia en DCF. Conclusiones. El avance los metodos de diagnostico prequirurgico y de procedimientos quirurgicos esta permitiendo ofrecer un tratamiento exitoso en edades tempranas a pacientes con DCF previamente considerados 'no lesionales' y a pacientes con lesiones localizadas en la 'corteza elocuente'. La identificacion de fenotipos anatomoelectroclinicos de DCF permite establecer abordajes quirurgicos y expectativas de pronostico posquirurgico adecuadas a cada situacion, mejor en las DCF IIb transmantle y en las displasias de fondo de surco que en las DCF multilobares, en su mayoria DCF I.

  17. [DEMOCOPHES SPAIN AND ITS CONTRIBUTION TO THE HARMONIZATION OF EUROPEAN HUMAN BIOMONITORING].

    PubMed

    Esteban López, Marta; López Martín, Estrella; Rodríguez García, Carolina; Posada De la Paz, Manuel; Castaño Calvo, Argelia

    2015-07-01

    Objetivo: contribuir a la armonización europea de la biovigilancia en humanos (proyecto DEMOCOPHES) demostrando la utilidad de los estudios de biovigilancia para valorar la influencia de la dieta y los estilos de vida como vía de exposición a contaminantes ambientales. Métodos: se adaptó el protocolo europeo a las necesidades nacionales, siguiendo los controles de calidad definidos en él y sin comprometer la obtención de datos comparables entre los países participantes. Resultados: la adaptación nacional del protocolo europeo no presentó grandes dificultades y, salvo mínimas modificaciones, se respetó el diseño original del estudio. Participaron 134 parejas madre-hijo, seleccionados en un colegio de Añover de Tajo (Toledo) y tres colegios de Madrid. Los voluntarios donaron una muestra de pelo y de orina y contestaron a las preguntas del cuestionario epidemiológico. Se observaron diferencias significativas en la participación de los voluntarios en las dos localizaciones de muestreo. Discusión: la estandarización de todas las etapas de un estudio de biovigilancia en humanos es esencial para su desarrollo armonizado a escala internacional. Los resultados obtenidos han contribuido a la obtención de datos sobre exposición ambiental, por primera vez comparables en 17 países europeos, y han permitido observar diferencias relacionadas con la dieta y los hábitos de vida. Las experiencias y el material de trabajo desarrollado para el estudio piloto serán aplicables al diseño e implementación de futuros estudios de HBM.

  18. [Ethics committees in the experience of the IMSS: a Latin American instance].

    PubMed

    Valdez-Martínez, Edith; Mata-Valderrama, Guadalupe; Bedolla, Miguel; Fajardo-Dolci, Germán Enrique

    2015-01-01

    Introducción: el objetivo es examinar la situación actual de los comités hospitalarios de bioética (CHB) y de los comités locales de investigación y ética en investigación en salud (CLIEIS) del Instituto Mexicano del Seguro Social (IMSS). Métodos: estudio cuantitativo, transversal descriptivo, realizado entre octubre y noviembre de 2014. Se enviaron por correo electrónico dos cuestionarios, autoadministrados o de autorreporte, a todos los hospitales del IMSS (N = 262): uno para los CHB y otro para los CLIEIS. Cinco apartados contenían ambos cuestionarios: localización del comité, fecha en la que fue constituido, estado actual de actividad, composición, funciones y experiencia. Resultados: la tasa de respuesta fue de 85 %. Se identificaron 150 CHB activos y 67 CLIEIS activos. En ambos grupos predominó la profesión médica y el personal directivo entre sus integrantes. Los representantes de la ciudadanía sólo fueron reportados en siete CHB. La función primaria reportada por los CHB fue la consultiva, y su meta primaria: “mejorar la calidad de la atención médica”. Los CLIEIS señalaron como función primaria: “evaluar y dictaminar protocolos de investigación en salud” y dentro de sus metas el “proteger los derechos y el bienestar de los sujetos de investigación”. Conclusiones: ambos grupos de comités debieran ser evaluados regularmente a través de ciclos de auditoría con el propósito de identificar las acciones educativas que promuevan su eficiencia.

  19. Mini-mastoidectomía para anastomosis hipogloso-facial con sección parcial del nervio hipogloso

    PubMed Central

    Campero, Álvaro; Ajler, Pablo; Socolovsky, Mariano; Martins, Carolina; Rhoton, Albert

    2012-01-01

    Introducción: La anastomosis hipogloso-facial es la técnica de elección para la reparación de la parálisis facial cuando no se dispone de un cabo proximal sano del nervio facial. La técnica de anastomosis mediante fresado mastoideo y sección parcial del hipogloso minimiza la atrofia lingual sin sacrificar resultados a nivel facial. Método: La porción mastoidea del nervio facial transcurre por la pared anterior de la AM, a un promedio de 18+/-3 mm de profundidad respecto de la pared lateral. Se debe reconocer la cresta supramastoidea, desde la cual se marca una línea vertical paralela al eje mayor de la AM, 1 cm por detrás de la pared posterior del CAE El fresado se comienza desde la línea medio mastoidea hasta la pared posterior del CAE. Una vez encontrado el nervio facial en el tercio medio del canal mastoideo, el mismo es seguido hacia proximal y distal. Resultados: El abordaje descripto permite acceder al nervio facial intratemporal en su porción mastoidea, y efectuar un fresado óseo sin poner en riesgo al nervio o a estructuras vasculares cercanas. Se trata de un procedimiento técnicamente más sencillo que los abordajes amplios habitualmente utilizados al hueso temporal; no obstante su uso debe ser restringido mayormente a la anastomosis hipogloso-facial. Conclusión: Esta es una técnica relativamente sencilla, que puede ser reproducida por cirujanos sin mayor experiencia en el tema, luego de su paso por el laboratorio de anatomía. PMID:23596555

  20. [Type IV paraesophageal hernia with 60% of gastric necrosis. Case report].

    PubMed

    Navarro-Tovar, Fernando; Juárez-de La Torre, Juan Carlos; Pérez-Ayala, Luis Carlos; Quintero-Cabrera, Eduardo

    2014-01-01

    Antecedentes: las hernias paraesofágicas son de baja incidencia y generalmente asintomáticas; sin embargo, cuando provocan síntomas, el riesgo de complicaciones se incrementa y se convierten en una urgencia quirúrgica. Caso clínico: mujer de 53 años de edad, con cuadro clínico de tres semanas de evolución, caracterizado por dolor abdominal, náusea y vómito ocasionales, a lo que se agregó oclusión intestinal 24 horas antes de que acudiera a consulta. En la valoración radiográfica y tomográfica se observó una hernia paraesofágica que requería laparotomía exploradora. Se encontró un defecto diafragmático paraesofágico de 9 cm, con un saco herniario de contenido del estómago, colon transverso y epiplón, con necrosis gástrica de 60% (en el fondo y el cuerpo). Se le practicó una resección gástrica no anatómica y plastia diafragmática. El periodo postoperatorio fue complicado porque se le hicieron otras dos intervenciones quirúrgicas por dehiscencia de gastrectomía y una más por esofagostomía cervical y yeyunostomía tipo Witzel. Conclusiones: se recomienda la reparación electiva en todos los sujetos asintomáticos con hernia paraesofágica, con el fin de evitar las posibles complicaciones. El método de abordaje depende de la experiencia del cirujano y de las condiciones en que se encuentre la hernia y las estructuras involucradas al momento del diagnóstico.

  1. [What is the optimal dose for the prophylactic treatment of chronic migraine patients?].

    PubMed

    Irimia, Pablo; Esteve-Belloch, Patricia; Murie-Fernandez, Manuel; Martinez-Vila, Eduardo

    2014-03-10

    Introduccion. La OnabotulinumtoxinA (OnabotA) esta indicada para el tratamiento preventivo de los pacientes con diagnostico de migraña cronica. Existe cierta controversia acerca de cual es la dosis minima eficaz de OnabotA. Objetivo. Determinar cual es la dosis mas adecuada de OnabotA para el tratamiento de la migraña cronica. Desarrollo. Se revisan los estudios controlados frente a placebo, que han evaluado la eficacia y seguridad de OnabotA para el tratamiento de la migraña, prestando especial atencion a las dosis de toxina utilizadas. En los diferentes ensayos clinicos llevados a cabo antes del año 2010 se utilizaron distintos protocolos de infiltracion. La experiencia obtenida de los estudios previos permitio definir un protocolo de infiltracion que se utilizo en el programa PREEMPT, y que demostro que el tratamiento con OnabotA es seguro y eficaz en pacientes con migraña cronica. La dosis elegida en los ensayos PREEMPT 1 y 2 fue de 155-195 U, al observarse en los estudios en fase II que la dosis de 75 U no era eficaz y que la utilizacion de 150-200 U aumentaba la eficacia sin incrementar los efectos adversos. Ademas de la dosis, el paradigma de inyeccion PREEMPT tambien establece de manera detallada los puntos de inyeccion y la metodologia de infiltracion. Conclusiones. La evidencia cientifica disponible hasta la fecha sustenta que la dosis mas adecuada para el tratamiento de la migraña cronica es la utilizacion de al menos 150 U de OnabotA, y que la infiltracion debe realizarse con la metodologia definida en el paradigma de inyeccion PREEMPT.

  2. [Development and validation of an instrument designed to measure the impact of networks of support for breastfeeding].

    PubMed

    Baño Piñero, Isabel; Canteras Jordana, Manuel; Carrillo García, Cesar; López Araez, Alicia; Martínez Roche, María Emilia

    2015-04-01

    Antecedentes: partimos de la hipótesis de que no existen suficientes cuestionarios validados que midan el impacto de las redes de apoyo a la lactancia materna para población hispano hablante. Objetivo: Por ese motivo, nos planteamos como objetivo general de este trabajo, elaborar y validar (a nivel de contenido y constructo) un instrumento de medida cuantitativa. Método: Se evaluó la validez de contenido sometiendo el cuestionario a un juicio de expertos en lactancia materna de la Región de Murcia. La prueba piloto se llevó a cabo entre los meses de marzo y abril de 2014. Las encuestas fueron realizadas directamente por las usuarias que acudían al grupo de apoyo a la lactancia “Lactando”. Para la validez de constructo se realizó un análisis factorial con el que se determinaron las distintas dimensiones que el cuestionario podría medir. Se realizó una estadística descriptiva de cada uno de los ítems. A través del análisis de componentes principales, se obtuvo la varianza total explicada, determinando así, los factores con los elementos que los definían. Resultados: A través del análisis factorial, el cuestionario obtuvo una alta consistencia interna para sus cinco componentes (satisfacción, consultas, experiencia, problemas y apoyo), consiguiendo valores de 0,942 a 0,632. Y un porcentaje de varianza total explicada elevado (11,157% - 5,093%). Conclusión: Este estudio ha servido para crear un instrumento pertinente y válido a nivel de contenido y de constructo, capaz de medir el impacto de las redes de apoyo a la lactancia a través de 5 dimensiones.

  3. Inclusion of Astronomy Themes in an Inovative Approach of Informal Physics Teaching for High School Students. (Spanish Title: Inclusión de Temas Astronómicos en Uma Abordaje Innovadora de la Enseñanza Informal de Física Para Estudiantes de Secumdaria.) Inclusão de Temas Astronômicos Numa Abordagem Inovadora do Ensino Informal de Física Para Estudantes do Ensino Médio

    NASA Astrophysics Data System (ADS)

    Tiara Mota, Aline; de Morais Bonomini, Iracema Ariel; Meloni Martins Rosado, Ricardo

    2009-12-01

    The current work reports on an experience on Astronomy education at the Federal University of Itajubá through an extra-curricular course offered for High School students. This initiative was motivated by the low attention paid to the Astronomy subjects at this stage of the Brazilian Formal Education, in spite that the National Curricular Parameters (PCN and PCN+, in Brazil) point out the importance of their inclusion Este artículo relata una experiencia en la enseñanza de la astronomía efectuada en la Universidad Federal de Itajubá en la forma de un curso de extensión orientado para los estudiantes del colegio secundario. Esta iniciativa surgió de constatar la poca atención dada a la Astronomía en esta etapa de la Educación formal brasileña, a pesar que los Parámetros Curriculares Nacionales (PCN y PCN+, en Brasil) destacan la importancia de su inclusión. Este artigo relata uma experiência em ensino de Astronomia realizada na Universidade Federal de Itajubá na forma de um curso de extensão voltado para alunos do Ensino Médio. Esta iniciativa surgiu da pouca atenção que se dá à Astronomia nesta etapa da Educação embora os Parâmetros Curriculares Nacionais (PCN e PCN+) apontem a importância de sua inclusão.

  4. [Migraine and evolutionary theory: paths for a clinical approach].

    PubMed

    Alvaro-Gonzalez, L C

    2016-10-01

    Introduccion. La migraña es un trastorno muy comun, con incidencia en aumento. La teoria evolutiva permite explicar su aparicion, dadas las ventajas que aportaba a grupos originarios de Homo sapiens una mayor reactividad a estimulos, y la presencia creciente de interaccion con factores ambientales. Analizamos estos aspectos a traves de los mecanismos potenciales que los explican. Desarrollo. El diseño de los organismos y sus respuestas ambientales surgen para mejorar la supervivencia. Asi, el dolor y la cefalea pueden entenderse como respuestas homeostaticas y adaptativas. Menos del 10% de la poblacion no tiene experiencia de cefalea, y el fenotipo migrañoso es una repuesta dolorosa comun en formas secundarias y sindromicas de cefalea. Estas caracteristicas se entienden segun rasgos neurofisiologicos especificos (falta de habituacion, sensibilizacion y baja preactivacion), caracteristicas geneticas (trastorno poligenico con multiples genes de baja penetrancia, que interaccionan con el ambiente y que son comunes a los de los trastornos comorbidos, como depresion-ansiedad) e interaccion ambiental en las sociedades modernas (aumento del numero de ciclos estrogenicos, y especialmente sobreexposicion al estres). Conclusiones. Lo que fue una ventaja evolutiva se ha transformado en la sociedad moderna en un trastorno muy prevalente y frecuentemente incapacitante. Es el resultado de una interaccion con sobrecarga de estimulos externos (estres) e internos (hormonales), lo que, de acuerdo con la teoria evolutiva, convertiria a la migraña en una enfermedad por desajuste. Los efectos ocurririan precozmente, en la infancia, a traves de mecanismos de epigenetica. Se obtendria un gran beneficio terapeutico mediante intervenciones poblacionales y educativas que incorporen estos aspectos.

  5. [Status epilepticus in paediatrics: a retrospective study and review of the literature].

    PubMed

    Moreno-Medinilla, Esther E; Negrillo-Ruano, Rocío; Calvo-Medina, Rocío; Mora-Ramírez, M Dolores; Martínez-Antón, Jacinto L

    2015-05-01

    Introduccion. El estado epileptico (EE) es la emergencia neurologica mas frecuente en pediatria. Dada la posibilidad de secuelas neurologicas y mortalidad asociadas, requiere un tratamiento agresivo precoz. Pacientes y metodos. Estudio descriptivo retrospectivo a traves de la revision de historias clinicas de pacientes ingresados en nuestro hospital entre 2010-2013 con diagnostico de EE. El objetivo fue describir las caracteristicas epidemiologicas y el manejo de estos pacientes, asi como revisar la bibliografia disponible sobre este tema. Resultados. Hemos recogido 39 pacientes (25 varones) y 51 episodios de EE. Edad media: 4,8 años. Tenian enfermedad de base 22 pacientes. Dieciocho eran epilepticos conocidos y cinco tuvieron un EE previo. De los 51 episodios de EE, 33 fueron sintomaticos, 15 febriles y tres criptogenicos. Los tipos de EE fueron: 25 parciales (de ellos, 16 complejos) y 26 generalizados. El tratamiento de primera eleccion fue benzodiacepinas en 47 pacientes (40, diacepam), fenitoina en tres y acido valproico en uno. Veintisiete pacientes precisaron farmacos de segunda linea: 16, acido valproico; ocho, fenitoina; dos, fenobarbital; y uno, levetiracetam. Diez pacientes precisaron farmacos de tercera linea para la induccion del coma: el midazolam fue el mas utilizado en nuestro centro, seguido del tiopental y el propofol. Dos EE superrefractarios requirieron inmunoglobulinas y corticoides sistemicos por presentarse en el curso de encefalitis autoinmunes. Conclusiones. Debe plantearse el esquema terapeutico del EE desde el inicio de cualquier crisis convulsiva. El tratamiento es escalonado, con benzodiacepinas en la primera etapa, antiepilepticos de amplio espectro y disponibilidad intravenosa en la segunda (acido valproico, levetiracetam en el EE generalizado y fenitoina en el EE focal), mientras que el tercer nivel varia en funcion de la experiencia de cada equipo.

  6. [Endovascular treatment of spinal dorsal intradural arteriovenous fistulas].

    PubMed

    Santos-Franco, Jorge Arturo; Collado-Arce, María Griselda Lizbeth; Dávila-Romero, Julio César; Saavedra-Andrade, Rafael; Sandoval-Balanzario, Miguel Antonio

    2015-01-01

    Introducción: las fístulas arteriovenosas intradurales dorsales espinales (FAVIDE) son lesiones poco frecuentes y complejas que son subdiagnósticadas y condicionan discapacidad. El objetivo es presentar nuestra experiencia en el manejo endovascular. Métodos: estudio ambispectivo de pacientes con FAVIDE, tratados mediante terapia endovascular (TEV) con n-butil-cianoacrilato en el periodo de 2007 a 2013. Resultados: se incluyeron 15 pacientes con edad media de 37 años. En 12 casos la presentación fue progresiva e insidiosa en un lapso de entre 6 meses y un año, mientras que 3 presentaron hemorragia. La lesión tuvo localización torácica en 73 % de los casos, lumbar en 20 % y cervical en 7 %. Previo al tratamiento observamos discapacidad de grados 5 y 4 en 73 %, y 67 % tenían alteraciones de la micción de grado 3. Como complicaciones, solo una paciente tuvo deterioro del estado de alerta transitorio 6 horas después del procedimiento. Se encontró una mejoría hacia los grados 1 y 2 de discapacidad, a las 48 horas, 3 y 6 meses, de 53 %, 73 % y 87 %, respectivamente. Conclusiones: con la TEV se tiene un tiempo quirúrgico corto, el volumen de hemorragia es bajo y la estancia hospitalaria es corta, respecto de otras técnicas quirúrgicas. La TEV es un procedimiento seguro y con efectividad significativa en el tratamiento de FAVIDE. Esta es la primera serie de casos tratados con TEV en México.

  7. Acceptability of an Embodied Conversational Agent-based Computer Application for Hispanic Women

    PubMed Central

    Wells, Kristen J.; Vázquez-Otero, Coralia; Bredice, Marissa; Meade, Cathy D.; Chaet, Alexis; Rivera, Maria I.; Arroyo, Gloria; Proctor, Sara K.; Barnes, Laura E.

    2015-01-01

    There are few Spanish language interactive, technology-driven health education programs. Objectives of this feasibility study were to: 1) learn more about computer and technology usage among Hispanic women living in a rural community; and 2) evaluate acceptability of the concept of using an embodied conversational agent (ECA) computer application among this population. A survey about computer usage history and interest in computers was administered to a convenience sample of 26 women. A sample video prototype of a hospital discharge ECA was administered followed by questions to gauge opinion about the ECA. Data indicate women exhibited both a high level of computer experience and enthusiasm for the ECA. Feedback from community is essential to ensure equity in state of the art dissemination of health information. Hay algunos programas interactivos en español que usan la tecnología para educar sobre la salud. Los objetivos de este estudio fueron: 1) aprender más sobre el uso de computadoras y tecnología entre mujeres Hispanas que viven en comunidades rurales y 2) evaluar la aceptabilidad del concepto de usar un programa de computadora utilizando un agente de conversación encarnado (ECA) en esta población. Se administro una encuesta sobre el historial de uso y del interés de aprender sobre computadoras fue a 26 mujeres por muestreo de conveniencia. Un ejemplo del prototipo ECA en forma de video de un alta hospitalaria fue administrado y fue seguido por preguntas sobre la opinión que tenían del ECA. Los datos indican que las mujeres mostraron un alto nivel de experiencia con las computadoras y un alto nivel de entusiasmo sobre el ECA. La retroalimentación de la comunidad es esencial para asegurar equidad en la diseminación de información sobre la salud con tecnología de punta. PMID:26671558

  8. The effect of scientific evidence on conservation practitioners’ management decisions

    PubMed Central

    Walsh, Jessica C; Dicks, Lynn V; Sutherland, William J

    2015-01-01

    management outcomes. El Efecto de la Evidencia Científica sobre las Decisiones de Manejo de Quienes Practican la Conservación Resumen Una justificación mayor de la investigación en el manejo ambiental es que ayuda a quienes lo practican, aunque estudios previos muestran que rara vez se usa para informar sus decisiones. Probamos si quienes practican la conservación enfocada en el manejo de aves estaban dispuestos a usar una sinopsis de literatura científica relevante para informar sus decisiones de manejo. Esto permitió que examináramos si el uso limitado de información científica en el manejo se debe a una falta de acceso a la literatura científica o si se debe a que quienes practican la conservación no están interesados o no son capaces de incorporar la investigación a sus decisiones. En encuestas en línea les preguntamos a 92 practicantes de la conservación, la mayoría de Australia, Nueva Zelanda y el Reino Unido, que nos proporcionaran opiniones sobre 28 técnicas de manejo que podrían aplicarse para reducir la depredación de aves. Les pedimos sus opiniones antes y después de darles un resumen de la literatura sobre la efectividad de las intervenciones. Calificamos la efectividad general y la certidumbre de la evidencia para cada intervención por medio de un proceso de extracción por expertos – el método Delphi. Usamos las calificaciones de la efectividad para evaluar el nivel de entendimiento y de percatación de la literatura de quienes practican la conservación. En promedio, cada participante de la encuesta cambió su probabilidad de usar 45.7% de las intervenciones después de leer la sinopsis de la evidencia. Fue más probable que implementaran intervenciones efectivas y evitar acciones poco efectivas, lo que sugiere que sus estrategias de manejo futuras puedan ser más exitosas que las de práctica actual. Los practicantes con mayor experiencia tuvieron una menor probabilidad de cambiar sus prácticas de manejo que aquellos con menos

  9. Social Representations of Gynecologic Cancer Screening Assessment a Qualitative research on Ecuadorian women.

    PubMed

    Godoy, Yolanda; Godoy, Clara; Reyes, Juan

    2016-06-01

    The purpose of this work was to explore: knowledge, attitudes, and beliefs regarding gynecologic cancer screening on Ecuadorian women users of primary care facilities, to identify the social representations that users of health services make about these programs and their influence on the decision to undergo a screening. An exploratory and qualitative research design was held using focus groups and in-depth interviews for data collection. A narrative content analysis of the results was conducted. Women's knowledge on gynecological cancer screening was confusing. Most frequent misconceptions related to the pap smear were: the belief that it could be useful for detecting pregnancy, ovarian cysts or infections. Most of the participants stated that the pap smear procedure is a traumatic and painful experience. Regarding to mammography women said it was used for sick woman and this procedure by itself may cause cancer. El propósito de esta investigación fue explorar los conocimientos, actitudes y creencias respecto a los programas de detección del cáncer ginecológico entre usuarias de centros de atención primaria de salud para identificar las representaciones sociales que las usuarias de los servicios de salud elaboran acerca de estos programas y de los diferentes procedimientos que comprenden. El diseño de la investigación fue exploratorio y cualitativo, mediante grupos focales y entrevistas a profundidad, con el respectivo análisis narrativo e interpretativo del contenido. Se encontró conocimiento confuso acerca de los programas de tamizaje de cáncer ginecológico y dificultades asociadas a la realización de los procedimientos. Los significados más frecuentes acerca de los programas fueron: el uso de la citología cérvico-vaginal para detectar embarazo, quistes ováricos o infecciones. La mayoría de los participantes asociaba este procedimiento con una experiencia dolorosa y traumática. Respecto al autoexamen de mamas, lo calificaron como un masaje

  10. [In Process Citation].

    PubMed

    Chacón-Cuberos, Ramón; Castro-Sánchez, Manuel; Muros-Molina, José Joaquín; Espejo-Garcés, Tamara; Zurita-Ortega, Félix; Linares-Manrique, Marta

    2016-03-25

    Introducción: la dieta mediterránea (DM) representa uno de los modelos dietéticos más completos y sanos según expresan numerosos estudios. En este sentido, la etapa universitaria supone un cambio sustancial en los hábitos alimentarios de los adultos jóvenes, alejándose de los estándares asociados a la DM. Objetivo: determinar el nivel de adherencia a la DM de un sector de población universitaria, estableciendo patrones de relación con el tipo de población en el que reside y hábitos de ocio digital asociados a videojuegos. Material y métodos: en esta investigación de diseño descriptivo y corte transversal participaron 490 estudiantes universitarios (M = 22,8 años; DT = 3,639), realizándose la recogida de datos mediante los cuestionarios KIDMED, Cuestionario de Experiencias Relacionadas con los Videojuegos (CERV) y Cuestionario sobre los Hábitos de Consumo de Videojuegos (CHCV). Resultados: más del 70% de la muestra necesitaba mejorar su alimentación y solo un 26,1% se alimentaba adecuadamente. Asimismo, los niveles de adicción a los videojuegos mostraron que un 17,8% de los participantes manifestaba problemas potenciales y un 2,7% severos. Se encontraron diferencias estadísticas en las relaciones dadas para la adhesión a la DM, la frecuencia de uso de videojuegos y el número de videojuegos jugados, concretando que los hábitos de consumo de videojuegos influyen en la adhesión a la DM en la etapa universitaria. Conclusión: ante el bajo porcentaje de universitarios que siguen una dieta de calidad óptima y su relación con el uso de videojuegos, resulta de vital importancia la creación de programas de intervención que mejoren la alimentación de este sector y disminuyan el tiempo de ocio sedentario.

  11. Planificación Neuroquirúrgica con Software Osirix

    PubMed Central

    Jaimovich, Sebastián Gastón; Guevara, Martin; Pampin, Sergio; Jaimovich, Roberto; Gardella, Javier Luis

    2014-01-01

    Introducción: La individualidad anatómica es clave para reducir el trauma quirúrgico y obtener un mejor resultado. Actualmente, el avance en las neuroimágenes ha permitido objetivar esa individualidad anatómica, permitiendo planificar la intervención quirúrgica. Con este objetivo, presentamos nuestra experiencia con el software Osirix. Descripción de la técnica: Se presentan 3 casos ejemplificadores de 40 realizados. Caso 1: Paciente con meningioma de la convexidad parasagital izquierda en área premotora; Caso 2: Paciente con macroadenoma hipofisario, operada previamente por vía transeptoesfenoidal en otra institución con una resección parcial; Caso 3: Paciente con lesiones en pedúnculo cerebeloso medio bilateral. Se realizó la planificación prequirúrgica con el software OsiriX, fusionando y reconstruyendo en 3D las imágenes de TC e IRM, para analizar relaciones anatómicas, medir distancias, coordenadas y trayectorias, entre otras funciones. Discusión: El software OsiriX de acceso libre y gratuito permite al cirujano, mediante la fusión y reconstrucción en 3D de imágenes, analizar la anatomía individual del paciente y planificar de forma rápida, simple, segura y económica cirugías de alta complejidad. En el Caso 1 se pudo analizar las relaciones del tumor con las estructuras adyacentes para minimizar el abordaje. En el Caso 2 permitió comprender la anatomía post-operatoria previa del paciente, para determinar la trayectoria del abordaje transnasal endoscópico y la necesidad de ampliar su exposición, logrando la resección tumoral completa. En el Caso 3 permitió obtener las coordenadas estereotáxicas y trayectoria de una lesión sin representación tomográfica. Conclusión: En casos de no contar con costosos sistemas de neuronavegación o estereotáxia el software OsiriX es una alternativa a la hora de planificar la cirugía, con el objetivo de disminuir el trauma y la morbilidad operatoria. PMID:25165617

  12. Malformaciones arteriovenosas revisión y análisis descriptivo de 52 mavs tratadas durante el periodo de 2000-2010

    PubMed Central

    Rinaldi, Mariano; Mezzano, Emilio; Berra, Matias S.; Parés, Herald R.; Olocco, Ricardo V.; Papalini, Francisco R.

    2015-01-01

    Objetivo: Describir nuestra experiencia en el manejo de las Mavs analizando las características clínicas de los pacientes y los resultados postoperatorios. Método de análisis: Realizamos un análisis retrospectivo de 52 pacientes admitidos en el Servicio de neurocirugía para manejo quirúrgico: La información de referencia incluyo síntomas al inicio, diagnostico de admisión, hallazgos neurológicos y hallazgos en estudio por imágenes tales como tomografía cerebral, IRM cerebral y angiografía por sustracción digital. Los hallazgos postoperatorios de interés fueron: Mortalidad, examen neurológico postoperatorio y complicaciones asociadas. Presentamos nuestro análisis estadístico. Resultados: Edad promedio: 37,7 años. Distribución: Hombres: 61,5%. Motivos de consulta más frecuentes: Cefalea 63,5%, evento hemorrágico 59,6%, convulsiones 26,9%. Localización: Supratentorial: 92,9%, Infratentorial: 7,2%. 30,8%, de las Mavs fueron grado 2 y grado 3 Cincuenta por ciento del total presentaron aneurismas, del total de la MAVs, 59,6% debutó con sangrado, 26,9% con Crisis Convulsivas y 13,5% con déficit neurológico. Recibieron tratamiento endovascular previo a cirugía 30,7%. Durante el postoperatorio 23,1% presentaron mejoría cl