Sample records for site arc-loop roads

  1. A bounding-based solution approach for the continuous arc covering problem

    NASA Astrophysics Data System (ADS)

    Wei, Ran; Murray, Alan T.; Batta, Rajan

    2014-04-01

    Road segments, telecommunication wiring, water and sewer pipelines, canals and the like are important features of the urban environment. They are often conceived of and represented as network-based arcs. As a result of the usefulness and significance of arc-based features, there is a need to site facilities along arcs to serve demand. Examples of such facilities include surveillance equipment, cellular towers, refueling centers and emergency response stations, with the intent of being economically efficient as well as providing good service along the arcs. While this amounts to a continuous location problem by nature, various discretizations are generally relied upon to solve such problems. The result is potential for representation errors that negatively impact analysis and decision making. This paper develops a solution approach for the continuous arc covering problem that theoretically eliminates representation errors. The developed approach is applied to optimally place acoustic sensors and cellular base stations along a road network. The results demonstrate the effectiveness of this approach for ameliorating any error and uncertainty in the modeling process.

  2. ARC-2006-ACD06-0213-058

    NASA Image and Video Library

    2006-11-29

    Ames and Moffett Field (MFA) historical sites and memorials Site of the John W. Whisman Home. Headquarters and stopping place of the first stagecoach line between San Jose and San Francisco. Started in early autumn of 1849. Located at R.T.Jones Road and the Ames Child Care Center fence boundary.

  3. Prioritizing Historical Archaeological Sites at Fort Leonard Wood, Pulaski County, Missouri

    DTIC Science & Technology

    2012-04-01

    site. Dense tree cover impeded the GPS’ ability to determine its position, which made finding 23PU510 and 23PU512 a lengthy process. The spatial...the area as a “fallow field” (Figure 2). The area immediately surrounding the site is covered in under- growth and small deciduous trees . During the...flowers and catalpa and walnut trees . Looping past the west side of the house was the main road south from Bloodland. Immediately west of the road

  4. Closed-loop spontaneous baroreflex transfer function is inappropriate for system identification of neural arc but partly accurate for peripheral arc: predictability analysis

    PubMed Central

    Kamiya, Atsunori; Kawada, Toru; Shimizu, Shuji; Sugimachi, Masaru

    2011-01-01

    Abstract Although the dynamic characteristics of the baroreflex system have been described by baroreflex transfer functions obtained from open-loop analysis, the predictability of time-series output dynamics from input signals, which should confirm the accuracy of system identification, remains to be elucidated. Moreover, despite theoretical concerns over closed-loop system identification, the accuracy and the predictability of the closed-loop spontaneous baroreflex transfer function have not been evaluated compared with the open-loop transfer function. Using urethane and α-chloralose anaesthetized, vagotomized and aortic-denervated rabbits (n = 10), we identified open-loop baroreflex transfer functions by recording renal sympathetic nerve activity (SNA) while varying the vascularly isolated intracarotid sinus pressure (CSP) according to a binary random (white-noise) sequence (operating pressure ± 20 mmHg), and using a simplified equation to calculate closed-loop-spontaneous baroreflex transfer function while matching CSP with systemic arterial pressure (AP). Our results showed that the open-loop baroreflex transfer functions for the neural and peripheral arcs predicted the time-series SNA and AP outputs from measured CSP and SNA inputs, with r2 of 0.8 ± 0.1 and 0.8 ± 0.1, respectively. In contrast, the closed-loop-spontaneous baroreflex transfer function for the neural arc was markedly different from the open-loop transfer function (enhanced gain increase and a phase lead), and did not predict the time-series SNA dynamics (r2; 0.1 ± 0.1). However, the closed-loop-spontaneous baroreflex transfer function of the peripheral arc partially matched the open-loop transfer function in gain and phase functions, and had limited but reasonable predictability of the time-series AP dynamics (r2, 0.7 ± 0.1). A numerical simulation suggested that a noise predominantly in the neural arc under resting conditions might be a possible mechanism responsible for our findings. Furthermore, the predictabilities of the neural arc transfer functions obtained in open-loop and closed-loop conditions were validated by closed-loop pharmacological (phenylephrine and nitroprusside infusions) pressure interventions. Time-series SNA responses to drug-induced AP changes predicted by the open-loop transfer function matched closely the measured responses (r2, 0.9 ± 0.1), whereas SNA responses predicted by closed-loop-spontaneous transfer function deviated greatly and were the inverse of measured responses (r, −0.8 ± 0.2). These results indicate that although the spontaneous baroreflex transfer function obtained by closed-loop analysis has been believed to represent the neural arc function, it is inappropriate for system identification of the neural arc but is essentially appropriate for the peripheral arc under resting conditions, when compared with open-loop analysis. PMID:21486839

  5. 8. JAMESTOWN ISLAND LOOP ROAD, VIEW TO NORTHEAST OF WINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. JAMESTOWN ISLAND LOOP ROAD, VIEW TO NORTHEAST OF WINE MAKING SIGN (STOP 5). NOTE WICKET MADE OF VINES IN FOREGROUND. - Jamestown Island Loop Road, Jamestown Island, Jamestown, James City County, VA

  6. Impact of lipopolysaccharide-induced acute inflammation on baroreflex-controlled sympathetic arterial pressure regulation

    PubMed Central

    Tohyama, Takeshi; Kawada, Toru; Kishi, Takuya; Yoshida, Keimei; Nishikawa, Takuya; Mannoji, Hiroshi; Kamada, Kazuhiro; Sunagawa, Kenji; Tsutsui, Hiroyuki

    2018-01-01

    Background Lipopolysaccharide (LPS) induces acute inflammation, activates sympathetic nerve activity (SNA) and alters hemodynamics. Since the arterial baroreflex is a negative feedback system to stabilize arterial pressure (AP), examining the arterial baroreflex function is a prerequisite to understanding complex hemodynamics under LPS challenge. We investigated the impact of LPS-induced acute inflammation on SNA and AP regulation by performing baroreflex open-loop analysis. Methods Ten anesthetized Sprague-Dawley rats were used. Acute inflammation was induced by an intravenous injection of LPS (60 μg/kg). We isolated the carotid sinuses from the systemic circulation and controlled carotid sinus pressure (CSP) by a servo-controlled piston pump. We matched CSP to AP to establish the baroreflex closed-loop condition, whereas we decoupled CSP from AP to establish the baroreflex open-loop condition and changed CSP stepwise to evaluate the baroreflex open-loop function. We recorded splanchnic SNA and hemodynamic parameters under baroreflex open- and closed-loop conditions at baseline and at 60 and 120 min after LPS injection. Results In the baroreflex closed-loop condition, SNA continued to increase after LPS injection, reaching three-fold the baseline value at 120 min (baseline: 94.7 ± 3.6 vs. 120 min: 283.9 ± 31.9 a.u.). In contrast, AP increased initially (until 75 min), then declined to the baseline level. In the baroreflex open-loop condition, LPS reset the neural arc (CSP-SNA relationship) upward to higher SNA, while shifted the peripheral arc (SNA-AP relationship) downward at 120 min after the injection. As a result, the operating point determined by the intersection between function curves of neural arc and peripheral arc showed marked sympatho-excitation without substantial changes in AP. Conclusions LPS-induced acute inflammation markedly increased SNA via resetting of the baroreflex neural arc, and suppressed the peripheral arc. The balance between the augmented neural arc and suppressed peripheral arc determines SNA and hemodynamics in LPS-induced acute inflammation. PMID:29329321

  7. Impact of lipopolysaccharide-induced acute inflammation on baroreflex-controlled sympathetic arterial pressure regulation.

    PubMed

    Tohyama, Takeshi; Saku, Keita; Kawada, Toru; Kishi, Takuya; Yoshida, Keimei; Nishikawa, Takuya; Mannoji, Hiroshi; Kamada, Kazuhiro; Sunagawa, Kenji; Tsutsui, Hiroyuki

    2018-01-01

    Lipopolysaccharide (LPS) induces acute inflammation, activates sympathetic nerve activity (SNA) and alters hemodynamics. Since the arterial baroreflex is a negative feedback system to stabilize arterial pressure (AP), examining the arterial baroreflex function is a prerequisite to understanding complex hemodynamics under LPS challenge. We investigated the impact of LPS-induced acute inflammation on SNA and AP regulation by performing baroreflex open-loop analysis. Ten anesthetized Sprague-Dawley rats were used. Acute inflammation was induced by an intravenous injection of LPS (60 μg/kg). We isolated the carotid sinuses from the systemic circulation and controlled carotid sinus pressure (CSP) by a servo-controlled piston pump. We matched CSP to AP to establish the baroreflex closed-loop condition, whereas we decoupled CSP from AP to establish the baroreflex open-loop condition and changed CSP stepwise to evaluate the baroreflex open-loop function. We recorded splanchnic SNA and hemodynamic parameters under baroreflex open- and closed-loop conditions at baseline and at 60 and 120 min after LPS injection. In the baroreflex closed-loop condition, SNA continued to increase after LPS injection, reaching three-fold the baseline value at 120 min (baseline: 94.7 ± 3.6 vs. 120 min: 283.9 ± 31.9 a.u.). In contrast, AP increased initially (until 75 min), then declined to the baseline level. In the baroreflex open-loop condition, LPS reset the neural arc (CSP-SNA relationship) upward to higher SNA, while shifted the peripheral arc (SNA-AP relationship) downward at 120 min after the injection. As a result, the operating point determined by the intersection between function curves of neural arc and peripheral arc showed marked sympatho-excitation without substantial changes in AP. LPS-induced acute inflammation markedly increased SNA via resetting of the baroreflex neural arc, and suppressed the peripheral arc. The balance between the augmented neural arc and suppressed peripheral arc determines SNA and hemodynamics in LPS-induced acute inflammation.

  8. [Characteristics of body constitution and their relations to success in learning].

    PubMed

    Vikhruk, T I; Vikhruk, A Ia; Churganov, O A; Kolotov, V Ia

    2004-01-01

    Somatotype, finger dermatoglyphic pattern type, emotional stability level and foreign languages learning successfulness have been analyzed in 297 male cadets (aged 17-20 years) of the Military Institute of Physical Training. The cadets studied most frequently belonged to macrosomal and mesosomal somatotypes. In the study of finger patterns, loops were found to be most common (61.5% of all the patterns), while ringlets (33.4%) and arc patterns (5.1%) were less frequent. The amount of ulnar loops increased, while that of ringlets became less in the direction from micro- to macrosomal type. Almost half (46.9%) of the cadets appeared to be ambiverts, 30.8% were intraverts and the rest were extraverts. Loop patterns on all the fingers to a greater extent were found in cadets with high level of neuroticism; the cadets having lower neuroticism level were characterized by a combinations of loops with arcs on the left hand and arcs with ringlets on the right one. The cadets differing in foreign language learning successfulness level were different in their dermatoglyphic patterns and, especially in the prevalence of pattern combinations. So, among the excellent pupils the loop-arc combinations were 2.7 times more common and combinations of all three types of patterns (arcs, loops, ringlets) were 1.4 times more common.

  9. The location of the site of energy release in a solar X-ray subflare

    NASA Technical Reports Server (NTRS)

    Petrasso, R. D.; Kahler, S. W.; Krieger, A. S.; Silk, J. K.; Vaiana, G. S.

    1975-01-01

    A rapid sequence of high-resolution X-ray photographs was obtained by the S-054 X-ray Telescope Experiment on Skylab on 1973 September 1. During the course of this observation, photographs were obtained of a flarelike brightening in a simple, bipolar active region. Analysis reveals the following facts. The event had the form of a small, elongated bright feature whose narrowest dimension was less than seconds of arc. The brightness peak of the flarelike brightening was located within seconds of arc of the center of brightness of a preexisting loop structure that crossed the magnetic neutral line. This loop was observed to brighten gradually beginning approximately 10 minutes prior to the flarelike event. During the rise of the event, the 2-17 A X-ray brightness of the center of the subflare core rose by over a factor of 10 in a time period of 196 seconds or less.

  10. 76 FR 39069 - Foreign-Trade Zone 29-Louisville, KY; Application for Expansion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-05

    ... (316 acres)--Cedar Grove Business Park, on Highway 480, near Interstate 65, Shepherdsville, Bullitt... 10 (25 acres)--Global Port Business Park, 6201 Global Distribution Way, Louisville; Site 11 (261...), 8100 Air Commerce Drive (44 acres) and the Louisville Metro Commerce Center, 1900 Outer Loop Road (101...

  11. Brain-endocrine interactions: a microvascular route in the mediobasal hypothalamus.

    PubMed

    Ciofi, Philippe; Garret, Maurice; Lapirot, Olivier; Lafon, Pierrette; Loyens, Anne; Prévot, Vincent; Levine, Jon E

    2009-12-01

    Blood-borne hormones acting in the mediobasal hypothalamus, like those controlling food intake, require relatively direct access to target chemosensory neurons of the arcuate nucleus (ARC). An anatomical substrate for this is a permeable microvasculature with fenestrated endothelial cells in the ARC, a system that has awaited comprehensive documentation. Here, the immunofluorescent detection of endothelial fenestral diaphragms in the rat ARC allowed us to quantitate permeable microvessels throughout its rostrocaudal extent. We have determined that permeable microvessels are part of the subependymal plexus irrigating exclusively the ventromedial (vm) ARC from the subadjacent neuroendocrine median eminence. Unexpectedly, permeable microvessels were concentrated proximal to the pituitary stalk. This marked topography strongly supports the functional importance of retrograde blood flow from the pituitary to the vmARC, therefore making a functional relationship between peripheral long-loop, pituitary short-loop, and neuroendocrine ultra-short loop feedback, altogether converging for integration in the vmARC (formerly known as the hypophysiotrophic area), thereby so pivotal as a multicompetent brain endocrinostat.

  12. A temperature controller board for the ARC controller

    NASA Astrophysics Data System (ADS)

    Tulloch, Simon

    2016-07-01

    A high-performance temperature controller board has been produced for the ARC Generation-3 CCD controller. It contains two 9W temperature servo loops and four temperature input channels and is fully programmable via the ARC API and OWL data acquisition program. PI-loop control is implemented in an on-board micro. Both diode and RTD sensors can be used. Control and telemetry data is sent via the ARC backplane although a USB-2 interface is also available. Further functionality includes hardware timers and high current drivers for external shutters and calibration LEDs, an LCD display, a parallel i/o port, a pressure sensor interface and an uncommitted analogue telemetry input.

  13. 36 CFR 7.71 - Delaware Water Gap National Recreation Area.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... of L. R. 45012 (commonly known as the River Road). Loop Two is approximately 6 miles long and begins at the northwest end of Loop One; it goes northeasterly between the Delaware River and River Road for about one mile until it crosses River Road; then southwesterly along the ridge which is south of Hidden...

  14. 36 CFR 7.71 - Delaware Water Gap National Recreation Area.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of L. R. 45012 (commonly known as the River Road). Loop Two is approximately 6 miles long and begins at the northwest end of Loop One; it goes northeasterly between the Delaware River and River Road for about one mile until it crosses River Road; then southwesterly along the ridge which is south of Hidden...

  15. 36 CFR 7.71 - Delaware Water Gap National Recreation Area.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of L. R. 45012 (commonly known as the River Road). Loop Two is approximately 6 miles long and begins at the northwest end of Loop One; it goes northeasterly between the Delaware River and River Road for about one mile until it crosses River Road; then southwesterly along the ridge which is south of Hidden...

  16. 36 CFR 7.71 - Delaware Water Gap National Recreation Area.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of L. R. 45012 (commonly known as the River Road). Loop Two is approximately 6 miles long and begins at the northwest end of Loop One; it goes northeasterly between the Delaware River and River Road for about one mile until it crosses River Road; then southwesterly along the ridge which is south of Hidden...

  17. 36 CFR 7.71 - Delaware Water Gap National Recreation Area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of L. R. 45012 (commonly known as the River Road). Loop Two is approximately 6 miles long and begins at the northwest end of Loop One; it goes northeasterly between the Delaware River and River Road for about one mile until it crosses River Road; then southwesterly along the ridge which is south of Hidden...

  18. Cultural Resources Review for Closure of the nonradioactive Dangerous Waste Landfill and Solid Waste Landfill in the 600 Area, Hanford Site, Benton County, Washington, HCRC# 2010-600-018R

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gutzeit, Jennifer L.; Kennedy, Ellen P.; Bjornstad, Bruce N.

    2011-02-02

    The U.S. Department of Energy Richland Operations Office is proposing to close the Nonradioactive Dangerous Waste Landfill (NRDWL) and Solid Waste Landfill (SWL) located in the 600 Area of the Hanford Site. The closure of the NRDWL/SWL entails the construction of an evapotranspiration cover over the landfill. This cover would consist of a 3-foot (1-meter) engineered layer of fine-grained soil, modified with 15 percent by weight pea gravel to form an erosion-resistant topsoil that will sustain native vegetation. The area targeted for silt-loam borrow soil sits in Area C, located in the northern central portion of the Fitzner/Eberhardt Arid Landsmore » Ecology (ALE) Reserve Unit. The pea gravel used for the mixture will be obtained from both off-site commercial sources and an active gravel pit (Pit #6) located just west of the 300 Area of the Hanford Site. Materials for the cover will be transported along Army Loop Road, which runs from Beloit Avenue (near the Rattlesnake Barricade) east-northeast to the NRDWL/SWL, ending at State Route 4. Upgrades to Army Loop Road are necessary to facilitate safe bidirectional hauling traffic. This report documents a cultural resources review of the proposed activity, conducted according to Section 106 of the National Historic Preservation Act of 1966.« less

  19. Lane changing trajectory planning and tracking control for intelligent vehicle on curved road.

    PubMed

    Wang, Lukun; Zhao, Xiaoying; Su, Hao; Tang, Gongyou

    2016-01-01

    This paper explores lane changing trajectory planning and tracking control for intelligent vehicle on curved road. A novel arcs trajectory is planned for the desired lane changing trajectory. A kinematic controller and a dynamics controller are designed to implement the trajectory tracking control. Firstly, the kinematic model and dynamics model of intelligent vehicle with non-holonomic constraint are established. Secondly, two constraints of lane changing on curved road in practice (LCCP) are proposed. Thirdly, two arcs with same curvature are constructed for the desired lane changing trajectory. According to the geometrical characteristics of arcs trajectory, equations of desired state can be calculated. Finally, the backstepping method is employed to design a kinematic trajectory tracking controller. Then the sliding-mode dynamics controller is designed to ensure that the motion of the intelligent vehicle can follow the desired velocity generated by kinematic controller. The stability of control system is proved by Lyapunov theory. Computer simulation demonstrates that the desired arcs trajectory and state curves with B-spline optimization can meet the requirements of LCCP constraints and the proposed control schemes can make tracking errors to converge uniformly.

  20. 7. LASSEN PARK ROAD BRIDGE AT SULFUR WORKS. NOTE ROAD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. LASSEN PARK ROAD BRIDGE AT SULFUR WORKS. NOTE ROAD TRAVERSING DISTANT RIDGE BEYOND BRIDGE. SEEN FROM WEST OF HIGHWAY FROM OLD HIGHWAY LOOP. LOOKING E. - Lassen Park Road, Mineral, Tehama County, CA

  1. Wetland and Sensitive Species Survey Report for Y-12: Proposed Uranium Processing Facility (UPF)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Giffen, N.; Peterson, M.; Reasor, S.

    This report summarizes the results of an environmental survey conducted at sites associated with the proposed Uranium Processing Facility (UPF) at the Y-12 National Security Complex in September-October 2009. The survey was conducted in order to evaluate potential impacts of the overall project. This project includes the construction of a haul road, concrete batch plant, wet soil storage area and dry soil storage area. The environmental surveys were conducted by natural resource experts at ORNL who routinely assess the significance of various project activities on the Oak Ridge Reservation (ORR). Natural resource staff assistance on this project included the collectionmore » of environmental information that can aid in project location decisions that minimize impacts to sensitive resource such as significant wildlife populations, rare plants and wetlands. Natural resources work was conducted in various habitats, corresponding to the proposed areas of impact. Thc credentials/qualifications of the researchers are contained in Appendix A. The proposed haul road traverses a number of different habitats including a power-line right-of-way. wetlands, streams, forest and mowed areas. It extends from what is known as the New Salvage Yard on the west to the Polaris Parking Lot on the east. This haul road is meant to connect the proposed concrete batch plant to the UPF building site. The proposed site of the concrete batch plant itself is a highly disturbed fenced area. This area of the project is shown in Fig. 1. The proposed Wet Soils Disposal Area is located on the north side of Bear Creek Road at the former Control Burn Study Area. This is a second growth arce containing thick vegetation, and extensive dead and down woody material. This area of the project is shown in Fig. 2. Thc dry soils storage area is proposed for what is currently known as the West Borrow Area. This site is located on the west side of Reeves Road south of Bear Creek Road. The site is an early successional field. This area of the project is shown in Fig. 2.« less

  2. 19. Photographer unknown, circa 1950 'THE LOOP OVER' BRIDGE WAS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Photographer unknown, circa 1950 'THE LOOP OVER' BRIDGE WAS CONSTRUCTED ON NEWFOUND GAP ROAD TO REPLACE A SERIES OF DANGEROUS SWITCHBACKS. THIS ENGINEERING FEATURE QUICKLY BECAME A POPULAR TOURIST ATTRACTION. - Great Smoky Mountains National Park Roads & Bridges, Gatlinburg, Sevier County, TN

  3. A different time and place test of ArcHSI: A spatially explicit habitat model for elk in the Black Hills

    Treesearch

    Mark A. Rumble; Lakhdar Benkobi; R. Scott Gamo

    2007-01-01

    We tested predictions of the spatially explicit ArcHSI habitat model for elk. The distribution of elk relative to proximity of forage and cover differed from that predicted. Elk used areas near primary roads similar to that predicted by the model, but elk were farther from secondary roads. Elk used areas categorized as good (> 0.7), fair (> 0.42 to 0.7), and poor...

  4. 14 CFR 93.53 - Description of area.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Parkway; thence northerly along Lake Otis Parkway to its intersection with Abbott Road; thence east along Abbott Road to its intersection with Abbott Loop Road; thence north to its intersection with Tudor Road...

  5. A novel pulsed gas metal arc welding system with direct droplet transfer close-loop control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Q.; Li, P.; Zhang, L.

    1994-12-31

    In pulsed gas metal arc welding (GMAW), a predominant parameter that has to be monitored and controlled in real time for maintaining process stability and ensuring weld quality, is droplet transfer. Based on the close correlation between droplet transfer and arc light radiant flux in GMAW of steel and aluminum, a direct closed-loop droplet transfer control system for pulsed GMAW with arc light sensor has been developed. By sensing the droplet transfer directly via the arc light signal, a pulsed GMAW process with real and exact one-pulse, one-droplet transfer has been achieved. The novel pulsed GMAW machine consists of threemore » parts: a sensing system, a controlling system, and a welding power system. The software used in this control system is capable of data sampling and processing, parameter matching, optimum parameter restoring, and resetting. A novel arc light sensing system has been developed. The sensor is small enough to be clamped to a semiautomatic welding torch. Based on thissensingn system, a closed-loop droplet transfer control system of GMAW of steel and aluminum has been built and a commercial prototype has been made. The system is capable of keeping one-pulse, one-droplet transfer against external interferences. The welding process with this control system has been proved to be stable, quiet, with no spatter, and provide good weld formation.« less

  6. Visualization of Traffic Accidents

    NASA Technical Reports Server (NTRS)

    Wang, Jie; Shen, Yuzhong; Khattak, Asad

    2010-01-01

    Traffic accidents have tremendous impact on society. Annually approximately 6.4 million vehicle accidents are reported by police in the US and nearly half of them result in catastrophic injuries. Visualizations of traffic accidents using geographic information systems (GIS) greatly facilitate handling and analysis of traffic accidents in many aspects. Environmental Systems Research Institute (ESRI), Inc. is the world leader in GIS research and development. ArcGIS, a software package developed by ESRI, has the capabilities to display events associated with a road network, such as accident locations, and pavement quality. But when event locations related to a road network are processed, the existing algorithm used by ArcGIS does not utilize all the information related to the routes of the road network and produces erroneous visualization results of event locations. This software bug causes serious problems for applications in which accurate location information is critical for emergency responses, such as traffic accidents. This paper aims to address this problem and proposes an improved method that utilizes all relevant information of traffic accidents, namely, route number, direction, and mile post, and extracts correct event locations for accurate traffic accident visualization and analysis. The proposed method generates a new shape file for traffic accidents and displays them on top of the existing road network in ArcGIS. Visualization of traffic accidents along Hampton Roads Bridge Tunnel is included to demonstrate the effectiveness of the proposed method.

  7. Experimental evaluation of high performance base course and road base asphalt concrete with electric arc furnace steel slags.

    PubMed

    Pasetto, Marco; Baldo, Nicola

    2010-09-15

    The paper presents the results of a laboratory study aimed at verifying the use of two types of electric arc furnace (EAF) steel slags as substitutes for natural aggregates, in the composition of base course and road base asphalt concrete (BBAC) for flexible pavements. The trial was composed of a preliminary study of the chemical, physical, mechanical and leaching properties of the EAF steel slags, followed by the mix design and performance characterization of the bituminous mixes, through gyratory compaction tests, permanent deformation tests, stiffness modulus tests at various temperatures, fatigue tests and indirect tensile strength tests. All the mixtures with EAF slags presented better mechanical characteristics than those of the corresponding asphalts with natural aggregate and satisfied the requisites for acceptance in the Italian road sector technical standards, thus resulting as suitable for use in road construction. Copyright 2010 Elsevier B.V. All rights reserved.

  8. 9. STONE SLAB CULVERT UNDER CARRIAGE ROAD AT HORSESHOE CURVE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. STONE SLAB CULVERT UNDER CARRIAGE ROAD AT HORSESHOE CURVE NEAR GIANT SLIDE TRAIL MARKER ON AROUND-THE-MOUNTAIN LOOP. - Rockefeller Carriage Roads, Mount Desert Island, Bar Harbor, Hancock County, ME

  9. Structural Determinants at the Interface of the ARC2 and Leucine-Rich Repeat Domains Control the Activation of the Plant Immune Receptors Rx1 and Gpa21[C][W][OA

    PubMed Central

    Slootweg, Erik J.; Spiridon, Laurentiu N.; Roosien, Jan; Butterbach, Patrick; Pomp, Rikus; Westerhof, Lotte; Wilbers, Ruud; Bakker, Erin; Bakker, Jaap; Petrescu, Andrei-José; Smant, Geert; Goverse, Aska

    2013-01-01

    Many plant and animal immune receptors have a modular nucleotide-binding-leucine-rich repeat (NB-LRR) architecture in which a nucleotide-binding switch domain, NB-ARC, is tethered to a LRR sensor domain. The cooperation between the switch and sensor domains, which regulates the activation of these proteins, is poorly understood. Here, we report structural determinants governing the interaction between the NB-ARC and LRR in the highly homologous plant immune receptors Gpa2 and Rx1, which recognize the potato cyst nematode Globodera pallida and Potato virus X, respectively. Systematic shuffling of polymorphic sites between Gpa2 and Rx1 showed that a minimal region in the ARC2 and N-terminal repeats of the LRR domain coordinate the activation state of the protein. We identified two closely spaced amino acid residues in this region of the ARC2 (positions 401 and 403) that distinguish between autoactivation and effector-triggered activation. Furthermore, a highly acidic loop region in the ARC2 domain and basic patches in the N-terminal end of the LRR domain were demonstrated to be required for the physical interaction between the ARC2 and LRR. The NB-ARC and LRR domains dissociate upon effector-dependent activation, and the complementary-charged regions are predicted to mediate a fast reassociation, enabling multiple rounds of activation. Finally, we present a mechanistic model showing how the ARC2, NB, and N-terminal half of the LRR form a clamp, which regulates the dissociation and reassociation of the switch and sensor domains in NB-LRR proteins. PMID:23660837

  10. Structural determinants at the interface of the ARC2 and leucine-rich repeat domains control the activation of the plant immune receptors Rx1 and Gpa2.

    PubMed

    Slootweg, Erik J; Spiridon, Laurentiu N; Roosien, Jan; Butterbach, Patrick; Pomp, Rikus; Westerhof, Lotte; Wilbers, Ruud; Bakker, Erin; Bakker, Jaap; Petrescu, Andrei-José; Smant, Geert; Goverse, Aska

    2013-07-01

    Many plant and animal immune receptors have a modular nucleotide-binding-leucine-rich repeat (NB-LRR) architecture in which a nucleotide-binding switch domain, NB-ARC, is tethered to a LRR sensor domain. The cooperation between the switch and sensor domains, which regulates the activation of these proteins, is poorly understood. Here, we report structural determinants governing the interaction between the NB-ARC and LRR in the highly homologous plant immune receptors Gpa2 and Rx1, which recognize the potato cyst nematode Globodera pallida and Potato virus X, respectively. Systematic shuffling of polymorphic sites between Gpa2 and Rx1 showed that a minimal region in the ARC2 and N-terminal repeats of the LRR domain coordinate the activation state of the protein. We identified two closely spaced amino acid residues in this region of the ARC2 (positions 401 and 403) that distinguish between autoactivation and effector-triggered activation. Furthermore, a highly acidic loop region in the ARC2 domain and basic patches in the N-terminal end of the LRR domain were demonstrated to be required for the physical interaction between the ARC2 and LRR. The NB-ARC and LRR domains dissociate upon effector-dependent activation, and the complementary-charged regions are predicted to mediate a fast reassociation, enabling multiple rounds of activation. Finally, we present a mechanistic model showing how the ARC2, NB, and N-terminal half of the LRR form a clamp, which regulates the dissociation and reassociation of the switch and sensor domains in NB-LRR proteins.

  11. ARC-2009-ACD09-0068-038

    NASA Image and Video Library

    2009-04-22

    Tour DE Ames Bicycle event (start at Macon Road Gate - ending a the Old Mimi Mart on R.T. Jones Road) Deb Feng, Chief Center Operations (acting), starts off the race with fellow bikers on the first Tour de Ames

  12. THE "MUD VOLCANO," A STINKY THERMAL FEATURE ON THE GRAND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    THE "MUD VOLCANO," A STINKY THERMAL FEATURE ON THE GRAND LOOP ROAD. ACIDIC HOT SPRINGS HAVE REDUCED THE UNDERLYING LAVA TO A FINE CLAY, PRODUCING AN AREA OF BOILING MUD. THE ODOR OF ROTTEN EGGS IS FROM HYDROGEN SULFIDE GAS. - Grand Loop Road, Forming circuit between Mammoth Hot Springs, Norris Junction, Madison Junction, Old Faithful, Mammoth, Park County, WY

  13. Inland area contingency plan and maps for Pennsylvania (on CD-ROM). Data file

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-12-01

    EPA Region III has assembled on this CD a multitude of environmental data, in both visual and textual formats. While targeted for Facility Response Planning under the Oil Pollution Act of 1990, this information will prove helpful to anyone in the environmental arena. Specifically, the CD will aid contingency planning and emergency response personnel. Combining innovative GIS technology with EPA`s state-specific data allows you to display maps, find and identify map features, look at tabular information about map features, and print out maps. The CD was designed to be easy to use and incorporates example maps as well as helpmore » sections describing the use of the environmental data on the CD, and introduces you to the IACP Viewer and its capabilities. These help features will make it easy for you to conduct analysis, produce maps, and browse the IACP Plan. The IACP data are included in two formats: shapefiles, which can be viewed with the IACP Viewer or ESRI`s ArcView software (Version 2.1 or higher), and ARC/INFO export files, which can be imported into ARC/INFO or converted to other GIS data formats. Point Data Sources: Sensitive Areas, Surface Drinking Water Intakes, Groundwater Intakes, Groundwater Supply Facilities, NPL (National Priority List) Sites, FRP (Facility Response Plan) Facilities, NPDES (National Pollutant Discharge Elimination System) Facilities, Hospitals, RCRA (Resource Conservation and Recovery Act) Sites, TRI (Toxic Release Inventory) Sites, CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act) Sites Line Data Sources: TIGER Roads, TIGER Railroads, TIGER Hydrography, Pipelines Polygon Data Sources: State Boundaries, County Boundaries, Watershed Boundaries (8-digit HUC), TIGER Hydrography, Public Lands, Populated Places, IACP Boundaries, Coast Guard Boundaries, Forest Types, US Congressional Districts, One-half Mile Buffer of Surface Drinking Water Intakes.« less

  14. Inland area contingency plan and maps for Virginia (on CD-ROM). Data file

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-12-01

    EPA Region III has assembled on this CD a multitude of environmental data, in both visual and textual formats. While targeted for Facility Response Planning under the Oil Pollution Act of 1990, this information will prove helpful to anyone in the environmental arena. Specifically, the CD will aid contingency planning and emergency response personnel. Combining innovative GIS technology with EPA`s state-specific data allows you to display maps, find and identify map features, look at tabular information about map features, and print out maps. The CD was designed to be easy to use and incorporates example maps as well as helpmore » sections describing the use of the environmental data on the CD, and introduces you to the IACP Viewer and its capabilities. These help features will make it easy for you to conduct analysis, produce maps, and browse the IACP Plan. The IACP data are included in two formats: shapefiles, which can be viewed with the IACP Viewer or ESRI`s ArcView software (Version 2.1 or higher), and ARC/INFO export files, which can be imported into ARC/INFO or converted to other GIS data formats. Point Data Sources: Sensitive Areas, Surface Drinking Water Intakes, Groundwater Intakes, Groundwater Supply Facilities, NPL (National Priority List) Sites, FRP (Facility Response Plan) Facilities, NPDES (National Pollutant Discharge Elimination System) Facilities, Hospitals, RCRA (Resource Conservation and Recovery Act) Sites, TRI (Toxic Release Inventory) Sites, CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act) Sites Line Data Sources: TIGER Roads, TIGER Railroads, TIGER Hydrography, Pipelines Polygon Data Sources: State Boundaries, County Boundaries, Watershed Boundaries (8-digit HUC), TIGER Hydrography, Public Lands, Populated Places, IACP Boundaries, Coast Guard Boundaries, Forest Types, US Congressional Districts, One-half Mile Buffer of Surface Drinking Water Intakes.« less

  15. The NASA John C. Stennis Environmental Geographic Information System

    NASA Technical Reports Server (NTRS)

    Cohan, Tyrus; Grant, Kerry

    2002-01-01

    In addition to the Environmental Geographic Information System (EGIS) presentation, we will present two live demonstrations of a portion of the work being performed in support of environmental operations onsite and NASA-wide. These live demonstrations will showcase the NASA EGIS database through working versions of two software packages available from Environmental Systems Research Institute, Inc. (ESRI, Inc.): ArcIMS 3.0 and either ArcView 3.2a or ArcGIS 8.0.2. Using a standard web browser, the ArcIMS demo will allow users to access a project file containing several data layers found in the EGIS database. ArcIMS is configured so that a single computer can be used as the data server and as the user interface, which allows for maximum Internet security because the computer being used will not actually be connected to the World Wide Web. Further, being independent of the Internet, the demo will run at an increased speed. This demo will include several data layers that are specific to Stennis Space Center. The EGIS database demo is a representative portion of the entire EGIS project sent to NASA Headquarters last year. This demo contains data files that are readily available at various government agency Web sites for download. Although these files contain roads, rails, and other infrastructure details, they are generalized and at a small enough scale that they provide only a general idea of each NASA center's surroundings rather than specific details of the area.

  16. Geospatial Assessment of Cholera in a Rapidly Urbanizing Environment.

    PubMed

    Olanrewaju, Olajumoke Esther; Adepoju, Kayode Adewale

    2017-01-01

    This study mapped out and investigated the spatial relationship between cholera incidences and environmental risk factors in the study area. The study area was stratified into eight zones. Water samples from each zone were collected and analyzed to determine the colony forming units. GIS layers including housing density, digitized roads, rivers, buildings, and cholera incidence data from hospital archives were also collected and analyzed using ArcGIS 10.1. It was observed that there was an association between the ERFs ( p < 0.001). Similarly, 18 out of the 44 waste dump sites, seven out of 18 markets, and two out of 36 abattoirs were found near the historical cholera cases. Similarly, 4 (21.1%) locations were traced to be predominantly close to rivers and waste dump site. All the historical cholera cases were found adjoining to roads and buildings. Highest CFU count was found in the wells and streams of areas with a cluster of all the environmental risk factors and high housing density. This study revealed that waste dump sites and market had the highest predisposing attribute while the least was abattoir. The uniqueness of the study lies in the combination of mapping and microbial analyses to identify and assess the pattern of cholera risk and also to provide clear information for development of strategies for environmental supervision.

  17. 77 FR 55452 - Lynn Canal-Icy Strait Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-10

    ... infrastructure (roads & trails), implementing stewardship objectives that enhance forested ecosystems, and/or... room, Admirality National Monument Office, 8510 Mendenhall Loop Road, Juneau, AK 99801. The public may attend the meeting via Video Teleconference (VTC) at the Hoonah Ranger District office, 430A Airport Road...

  18. Integrated optical sensor

    DOEpatents

    Watkins, Arthur D.; Smartt, Herschel B.; Taylor, Paul L.

    1994-01-01

    An integrated optical sensor for arc welding having multifunction feedback control. The sensor, comprising generally a CCD camera and diode laser, is positioned behind the arc torch for measuring weld pool position and width, standoff distance, and post-weld centerline cooling rate. Computer process information from this sensor is passed to a controlling computer for use in feedback control loops to aid in the control of the welding process. Weld pool position and width are used in a feedback loop, by the weld controller, to track the weld pool relative to the weld joint. Sensor standoff distance is used in a feedback loop to control the contact tip to base metal distance during the welding process. Cooling rate information is used to determine the final metallurgical state of the weld bead and heat affected zone, thereby controlling post-weld mechanical properties.

  19. Integrated optical sensor

    DOEpatents

    Watkins, A.D.; Smartt, H.B.; Taylor, P.L.

    1994-01-04

    An integrated optical sensor for arc welding having multifunction feedback control is described. The sensor, comprising generally a CCD camera and diode laser, is positioned behind the arc torch for measuring weld pool position and width, standoff distance, and post-weld centerline cooling rate. Computer process information from this sensor is passed to a controlling computer for use in feedback control loops to aid in the control of the welding process. Weld pool position and width are used in a feedback loop, by the weld controller, to track the weld pool relative to the weld joint. Sensor standoff distance is used in a feedback loop to control the contact tip to base metal distance during the welding process. Cooling rate information is used to determine the final metallurgical state of the weld bead and heat affected zone, thereby controlling post-weld mechanical properties. 6 figures.

  20. 36 CFR 7.86 - Big Cypress National Preserve.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Road (State Road #B94). (B) The area north of Tamiami Trail. (ii) The following areas which are shown... of the Superintendent, are closed to motorized vehicles: (A) The areas between the Loop Road (State... signs, or by marking on a map which shall be available for public inspection at the office of the...

  1. 36 CFR 7.86 - Big Cypress National Preserve.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Road (State Road #B94). (B) The area north of Tamiami Trail. (ii) The following areas which are shown... of the Superintendent, are closed to motorized vehicles: (A) The areas between the Loop Road (State... signs, or by marking on a map which shall be available for public inspection at the office of the...

  2. 36 CFR 7.86 - Big Cypress National Preserve.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Road (State Road #B94). (B) The area north of Tamiami Trail. (ii) The following areas which are shown... of the Superintendent, are closed to motorized vehicles: (A) The areas between the Loop Road (State... signs, or by marking on a map which shall be available for public inspection at the office of the...

  3. 36 CFR 7.86 - Big Cypress National Preserve.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Road (State Road #B94). (B) The area north of Tamiami Trail. (ii) The following areas which are shown... of the Superintendent, are closed to motorized vehicles: (A) The areas between the Loop Road (State... signs, or by marking on a map which shall be available for public inspection at the office of the...

  4. Application of geographical information system in disposal site selection for hazardous wastes.

    PubMed

    Rezaeimahmoudi, Mehdi; Esmaeli, Abdolreza; Gharegozlu, Alireza; Shabanian, Hassan; Rokni, Ladan

    2014-01-01

    The aim of this study was to provide a scientific method based on Geographical Information System (GIS) regarding all sustainable development measures to locate a proper landfill for disposal of hazardous wastes, especially industrial (radioactive) wastes. Seven effective factors for determining hazardous waste landfill were applied in Qom Province, central Iran. These criteria included water, slope, population centers, roads, fault, protected areas and geology. The Analysis Hierarchical Process (AHP) model based on pair comparison was used. First, the weight of each factor was determined by experts; afterwards each layer of maps entered to ARC GIS and with special weight multiplied together, finally the best suitable site was introduced. The most suitable sites for burial were in northwest and west of Qom Province and eventually five zones were introduced as the sample sites. GIs and AHP model is introduced as the technical, useful and accelerator tool for disposal site selection. Furthermore it is determined that geological factor is the most effective layer for site selection. It is suggested that geological conditions should be considered primarily then other factors are taken into consideration.

  5. 1. PARKING LOT BEFORE SOUTH ENTRANCE STATION, FACING N. PARK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. PARKING LOT BEFORE SOUTH ENTRANCE STATION, FACING N. PARK ENTRANCE SIGN IS IN TREES IN CENTER. - South Entrance Road, Between South park boundary & Village Loop Road, Grand Canyon, Coconino County, AZ

  6. Inland area contingency plan and maps for Delaware, Maryland, West Virginia, District of Columbia (on CD-ROM). Data file

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-12-01

    EPA Region III has assembled on this CD a multitude of environmental data, in both visual and textual formats. While targeted for Facility Response Planning under the Oil Pollution Act of 1990, this information will prove helpful to anyone in the environmental arena. Specifically, the CD will aid contingency planning and emergency response personnel. Combining innovative GIS technology with EPA`s state-specific data allows you to display maps, find and identify map features, look at tabular information about map features, and print out maps. The CD was designed to be easy to use and incorporates example maps as well as helpmore » sections describing the use of the environmental data on the CD, and introduces you to the IACP Viewer and its capabilities. These help features will make it easy for you to conduct analysis, produce maps, and browse the IACP Plan. The IACP data are included in two formats: shapefiles, which can be viewed with the IACP Viewer or ESRI`s ArcView software (Version 2.1 or higher), and ARC/INFO export files, which can be imported into ARC/INFO or converted to other GIS data formats. Point Data Sources: Sensitive Areas, Surface Drinking Water Intakes, Groundwater Intakes, Groundwater Supply Facilities, NPL (National Priority List) Sites, FRP (Facility Response Plan) Facilities, NPDES (National Pollutant Discharge Elimination System) Facilities, Hospitals, RCRA (Resource Conservation and Recovery Act) Sites, TRI (Toxic Release Inventory) Sites, CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act) Sites Line Data Sources: TIGER Roads, TIGER Railroads, TIGER Hydrography, Pipelines Polygon Data Sources: State Boundaries, County Boundaries, Watershed Boundaries (8-digit HUC), TIGER Hydrography, Public Lands, Populated Places, IACP Boundaries, Coast Guard Boundaries, Forest Types, US Congressional Districts, One-half Mile Buffer of Surface Drinking Water Intakes.« less

  7. Finding topological center of a geographic space via road network

    NASA Astrophysics Data System (ADS)

    Gao, Liang; Miao, Yanan; Qin, Yuhao; Zhao, Xiaomei; Gao, Zi-You

    2015-02-01

    Previous studies show that the center of a geographic space is of great importance in urban and regional studies, including study of population distribution, urban growth modeling, and scaling properties of urban systems, etc. But how to well define and how to efficiently extract the center of a geographic space are still largely unknown. Recently, Jiang et al. have presented a definition of topological center by their block detection (BD) algorithm. Despite the fact that they first introduced the definition and discovered the 'true center', in human minds, their algorithm left several redundancies in its traversal process. Here, we propose an alternative road-cycle detection (RCD) algorithm to find the topological center, which extracts the outmost road-cycle recursively. To foster the application of the topological center in related research fields, we first reproduce the BD algorithm in Python (pyBD), then implement the RCD algorithm in two ways: the ArcPy implementation (arcRCD) and the Python implementation (pyRCD). After the experiments on twenty-four typical road networks, we find that the results of our RCD algorithm are consistent with those of Jiang's BD algorithm. We also find that the RCD algorithm is at least seven times more efficient than the BD algorithm on all the ten typical road networks.

  8. RF Noise Generation in High-Pressure Short-Arc DC Xenon Lamps

    NASA Astrophysics Data System (ADS)

    Minayeva, Olga; Doughty, Douglas

    2007-10-01

    Continuous direct current xenon arcs will generate RF noise under certain circumstance, which can lead to excessive electro- magnetic interference in systems that use these arcs as light sources. Phenomenological observations are presented for xenon arcs having arc gaps ˜1 mm, cold fill pressures of ˜2.5 MPa, and currents up to 30 amps. Using a loop antenna in the vicinity of an operating lamp, it is observed that as the current to the arc is lowered there is a reproducible threshold at which the RF noise generation begins. This threshold is accompanied by a small abrupt drop in voltage (˜0.2 volts). The RF emission appears in pulses ˜150 nsec wide separated by ˜300 nec - the pulse interval decreases with decreasing current. The properties of the RF emission as a function of arc parameters (such as pressure, arc gap, electrode design) will be discussed and a semi-quantitative model presented.

  9. Identification of hypothalamic arcuate nucleus-specific enhancer region of Kiss1 gene in mice.

    PubMed

    Goto, Teppei; Tomikawa, Junko; Ikegami, Kana; Minabe, Shiori; Abe, Hitomi; Fukanuma, Tatsuya; Imamura, Takuya; Takase, Kenji; Sanbo, Makoto; Tomita, Koichi; Hirabayashi, Masumi; Maeda, Kei-ichiro; Tsukamura, Hiroko; Uenoyama, Yoshihisa

    2015-01-01

    Pulsatile secretion of GnRH plays a pivotal role in follicular development via stimulating tonic gonadotropin secretion in mammals. Kisspeptin neurons, located in the arcuate nucleus (ARC), are considered to be an intrinsic source of the GnRH pulse generator. The present study aimed to determine ARC-specific enhancer(s) of the Kiss1 gene by an in vivo reporter assay. Three green fluorescent protein (GFP) reporter constructs (long, medium length, and short) were generated by insertion of GFP cDNA at the Kiss1 locus. Transgenic female mice bearing the long and medium-length constructs showed apparent GFP signals in kisspeptin-immunoreactive cells in both the ARC and anteroventral periventricular nucleus, in which another population of kisspeptin neurons are located. On the other hand, transgenic mice bearing 5'-truncated short construct showed few GFP signals in the ARC kisspeptin-immunoreactive cells, whereas they showed colocalization of GFP- and kisspeptin-immunoreactivities in the anteroventral periventricular nucleus. In addition, chromatin immunoprecipitation and chromosome conformation capture assays revealed recruitment of unoccupied estrogen receptor-α in the 5'-upstream region and intricate chromatin loop formation between the 5'-upstream and promoter regions of Kiss1 locus in the ARC. Taken together, the present results indicate that 5'-upstream region of Kiss1 locus plays a critical role in Kiss1 gene expression in an ARC-specific manner and that the recruitment of estrogen receptor-α and formation of a chromatin loop between the Kiss1 promoter and the 5' enhancer region may be required for the induction of ARC-specific Kiss1 gene expression. These results suggest that the 5'-upstream region of Kiss1 locus functions as an enhancer for ARC Kiss1 gene expression in mice.

  10. Mobile platform for overhead detectors of road vehicles.

    DOT National Transportation Integrated Search

    2002-06-01

    The California Department of Transportation (CALTRANS) has a need to monitor traffic flow over freeways. Currently, this is done mainly : through the use of loop detectors. These are measuring devices that are buried under the road pavement, an...

  11. Comparative Analysis of InSAR Digital Surface Models for Test Area Bucharest

    NASA Astrophysics Data System (ADS)

    Dana, Iulia; Poncos, Valentin; Teleaga, Delia

    2010-03-01

    This paper presents the results of the interferometric processing of ERS Tandem, ENVISAT and TerraSAR- X for digital surface model (DSM) generation. The selected test site is Bucharest (Romania), a built-up area characterized by the usual urban complex pattern: mixture of buildings with different height levels, paved roads, vegetation, and water bodies. First, the DSMs were generated following the standard interferometric processing chain. Then, the accuracy of the DSMs was analyzed against the SPOT HRS model (30 m resolution at the equator). A DSM derived by optical stereoscopic processing of SPOT 5 HRG data and also the SRTM (3 arc seconds resolution at the equator) DSM have been included in the comparative analysis.

  12. Vortex and Sink Flows in Eruptive Flares as a Model for Coronal Implosions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zuccarello, F. P.; Aulanier, G.; Démoulin, P.

    Eruptive flares are sudden releases of magnetic energy that involve many phenomena, several of which can be explained by the standard 2D flare model and its realizations in 3D. We analyze a 3D magnetohydrodynamics simulation, in the framework of this model, that naturally explains the contraction of coronal loops in the proximity of the flare sites, as well as the inflow toward the region above the cusp-shaped loops. We find that two vorticity arcs located along the flanks of the erupting magnetic flux rope are generated as soon as the eruption begins. The magnetic arcades above the flux rope legsmore » are then subjected to expansion, rotation, or contraction depending on which part of the vortex flow advects them. In addition to the vortices, an inward-directed magnetic pressure gradient exists in the current sheet below the magnetic flux rope. It results in the formation of a sink that is maintained by reconnection. We conclude that coronal loop apparent implosions observed during eruptive flares are the result of hydromagnetic effects related to the generation of vortex and sink flows when a flux rope moves in a magnetized environment.« less

  13. Design and hardware-in-loop implementation of collision avoidance algorithms for heavy commercial road vehicles

    NASA Astrophysics Data System (ADS)

    Rajaram, Vignesh; Subramanian, Shankar C.

    2016-07-01

    An important aspect from the perspective of operational safety of heavy road vehicles is the detection and avoidance of collisions, particularly at high speeds. The development of a collision avoidance system is the overall focus of the research presented in this paper. The collision avoidance algorithm was developed using a sliding mode controller (SMC) and compared to one developed using linear full state feedback in terms of performance and controller effort. Important dynamic characteristics such as load transfer during braking, tyre-road interaction, dynamic brake force distribution and pneumatic brake system response were considered. The effect of aerodynamic drag on the controller performance was also studied. The developed control algorithms have been implemented on a Hardware-in-Loop experimental set-up equipped with the vehicle dynamic simulation software, IPG/TruckMaker®. The evaluation has been performed for realistic traffic scenarios with different loading and road conditions. The Hardware-in-Loop experimental results showed that the SMC and full state feedback controller were able to prevent the collision. However, when the discrepancies in the form of parametric variations were included, the SMC provided better results in terms of reduced stopping distance and lower controller effort compared to the full state feedback controller.

  14. ARC length control for plasma welding

    NASA Technical Reports Server (NTRS)

    Iceland, William F. (Inventor)

    1988-01-01

    A control system to be used with a plasma arc welding apparatus is disclosed. The plasma arc welding apparatus includes a plasma arc power supply, a contactor, and an electrode assembly for moving the electrode relative to a work piece. The electrode assembly is raised or lowered by a drive motor. The present apparatus includes a plasma arc adapter connected across the power supply to measure the voltage across the plasma arc. The plasma arc adapter forms a dc output signal input to a differential amplifier. A second input is defined by an adjustable resistor connected to a dc voltage supply to permit operator control. The differential amplifier forms an output difference signal provided to an adder circuit. The adder circuit then connects with a power amplifier which forms the driving signal for the motor. In addition, the motor connects to a tachometor which forms a feedback signal delivered to the adder to provide damping, therby avoiding servo loop overshoot.

  15. Vehicle load-equalization system

    NASA Technical Reports Server (NTRS)

    Creasy, W. K.

    1976-01-01

    System uses cables and associated pulleys to form closed-loop suspension system for terrain compensation. Loop causes reactions at each of three wheels in response to loading at remaining wheel. Simplicity of design should be of interest to designers and manufacturers of construction equipment and off-road vehicles.

  16. Manhole Cover Detection Using Vehicle-Based Multi-Sensor Data

    NASA Astrophysics Data System (ADS)

    Ji, S.; Shi, Y.; Shi, Z.

    2012-07-01

    A new method combined wit multi-view matching and feature extraction technique is developed to detect manhole covers on the streets using close-range images combined with GPS/IMU and LINDAR data. The covers are an important target on the road traffic as same as transport signs, traffic lights and zebra crossing but with more unified shapes. However, the different shoot angle and distance, ground material, complex street scene especially its shadow, and cars in the road have a great impact on the cover detection rate. The paper introduces a new method in edge detection and feature extraction in order to overcome these difficulties and greatly improve the detection rate. The LIDAR data are used to do scene segmentation and the street scene and cars are excluded from the roads. And edge detection method base on canny which sensitive to arcs and ellipses is applied on the segmented road scene and the interesting areas contain arcs are extracted and fitted to ellipse. The ellipse are then resampled for invariance to shooting angle and distance and then are matched to adjacent images for further checking if covers and . More than 1000 images with different scenes are used in our tests and the detection rate is analyzed. The results verified our method have its advantages in correct covers detection in the complex street scene.

  17. 77 FR 16059 - Draft Environmental Impact Statement; Izembek National Wildlife Refuge Land Exchange/Road...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-19

    ... Aleutian arc chain of volcanoes. Landforms include mountains, active volcanoes, U-shaped valleys, glacial...-foot Shishaldin Volcano. Shishaldin Volcano is a designated National Natural Landmark. Alaska Maritime...

  18. Late Palaeozoic to Triassic evolution of the Turan and Scythian platforms: The pre-history of the Palaeo-Tethyan closure

    NASA Astrophysics Data System (ADS)

    Natal'in, Boris A.; Şengör, A. M. Celâl

    2005-08-01

    A number of en échelon-arranged, southwest-facing arc fragments of Palaeozoic to Jurassic ages, sandwiched between two fairly straight east-northeast trending boundaries, constitute the basement of the Scythian and the Turan platforms located between the Laurasian and Tethyside units. They have until now largely escaped detection owing to extensive Jurassic and younger cover and the inaccessibility of the subsurface data to the international geological community. These units are separated from one another by linear/gently-curved faults of great length and steep dip. Those that are exposed show evidence of strike-slip motion. The arc units originally constituted parts of a single "Silk Road Arc" located somewhere south of the present-day central Asia for much of the Palaeozoic, although by the late Carboniferous they had been united into a continental margin arc south of the Tarim basin and equivalent units to the west and east. They were stacked into their present places in northern Afghanistan, Turkmenistan, Caucasus and the northern Black Sea by large-scale, right-lateral strike-slip coastwise transport along arc-slicing and arc-shaving strike-slip faults in the Triassic and medial Jurassic simultaneously with the subductive elimination of Palaeo-Tethys. This gigantic dextral zone ("the Silk Road transpression") was a trans-Eurasian structure and was active simultaneously with another, similar system, the Gornostaev keirogen and greatly distorted Eurasia. The late Palaeozoic to Jurassic internal deformation of the Dniepr-Donets aulacogen was also a part of the dextral strain in southern Europe. When the emplacement of the Scythian and Turan units was completed, the elimination of Palaeo-Tethys had also ended and Neo-Tethyan arcs were constructed atop their ruins, mostly across their southern parts. The western end of the great dextral zone that emplaced the Turan and Scythian units horsetails just east of north Dobrudja and a small component goes along the Tornquist-Teisseyre lineament.

  19. The StreamCat Dataset: Accumulated Attributes for NHDPlusV2 Catchments (Version 2.1) for the Conterminous United States: 2010 US Census Road Density

    EPA Pesticide Factsheets

    This dataset represents the road density within individual, local NHDPlusV2 catchments and upstream, contributing watersheds. Attributes of the landscape layer were calculated for every local NHDPlusV2 catchment and accumulated to provide watershed-level metrics. (See Supplementary Info for Glossary of Terms) This data set is derived from TIGER/Line Files of roads in the conterminous United States. Road density describes how many kilometers of road exist in a square kilometer. A raster was produced using the ArcGIS Line Density Tool to form the landscape layer for analysis. (see Data Sources for links to NHDPlusV2 data and Census Data) The (kilometer of road/square kilometer) was summarized by local catchment and by watershed to produce local catchment-level and watershed-level metrics as a continuous data type (see Data Structure and Attribute Information for a description).

  20. The Bacterial Response Regulator ArcA Uses a Diverse Binding Site Architecture to Regulate Carbon Oxidation Globally

    PubMed Central

    Park, Dan M.; Akhtar, Md. Sohail; Ansari, Aseem Z.; Landick, Robert; Kiley, Patricia J.

    2013-01-01

    Despite the importance of maintaining redox homeostasis for cellular viability, how cells control redox balance globally is poorly understood. Here we provide new mechanistic insight into how the balance between reduced and oxidized electron carriers is regulated at the level of gene expression by mapping the regulon of the response regulator ArcA from Escherichia coli, which responds to the quinone/quinol redox couple via its membrane-bound sensor kinase, ArcB. Our genome-wide analysis reveals that ArcA reprograms metabolism under anaerobic conditions such that carbon oxidation pathways that recycle redox carriers via respiration are transcriptionally repressed by ArcA. We propose that this strategy favors use of catabolic pathways that recycle redox carriers via fermentation akin to lactate production in mammalian cells. Unexpectedly, bioinformatic analysis of the sequences bound by ArcA in ChIP-seq revealed that most ArcA binding sites contain additional direct repeat elements beyond the two required for binding an ArcA dimer. DNase I footprinting assays suggest that non-canonical arrangements of cis-regulatory modules dictate both the length and concentration-sensitive occupancy of DNA sites. We propose that this plasticity in ArcA binding site architecture provides both an efficient means of encoding binding sites for ArcA, σ70-RNAP and perhaps other transcription factors within the same narrow sequence space and an effective mechanism for global control of carbon metabolism to maintain redox homeostasis. PMID:24146625

  1. Comparison of the physical and chemical characteristics of fine road dust at different urban sites.

    PubMed

    Lee, Kwang Yul; Batmunkh, Tsatsral; Joo, Hung Soo; Park, Kihong

    2018-04-18

    The size distribution and chemical components of a fine fraction (<2.5 μm) of road dust collected at urban sites in Korea (Gwangju) and Mongolia (Ulaanbaatar) where distinct urban characteristics exist were measured. A clear bimodal size distribution was observed for the resuspended fine road dust at the urban sites in Korea. The first mode peaked at 100-110 nm, and the second peak was observed at 435-570 nm. Ultrafine mode (~30 nm) was found for the fine road dust at the Mongolia site, which was significantly affected by residential coal/biomass burning. The contribution of the water-soluble ions to the fine road dust was higher at the sites in Mongolia (15.8-16.8%) than at those in Korea (1.2-4.8%). Sulfate and chloride were the most dominant ionic species for the fine road dust in Mongolia. As (arsenic) was also much higher for the Mongolian road dust than the others. The sulfate, chloride, and As mainly come from coal burning activity, suggesting that coal and biomass combustion in Mongolia during the heating season should affect the size and chemical components of the fine road dust. Cu (copper) and Zn (zinc), carbonaceous particles (organic carbon [OC] and elemental carbon [EC]) increased at sites in Korea, suggesting that the fine road dust at these sites was significantly affected by the high volume of traffic (engine emission and brake/tire wear). Our results suggest that chemical profiles for road dust specific to certain sites should be applied to more accurately apportion road dust source contributing to the ambient particulate matter. Size and chemical characteristics of fine road dust at sites having distinct urban characteristics were examined. Residential coal and biomass burning and traffic affected physiochemical properties of the fine road dust. Different road dust profiles at different sites should be needed to determine the ambient PM2.5 sources more accurately.

  2. Matrix Solution of Coupled Differential Equations and Looped Car Following Models

    ERIC Educational Resources Information Center

    McCartney, Mark

    2008-01-01

    A simple mathematical model for the behaviour of how vehicles follow each other along a looped stretch of road is described. The resulting coupled first order differential equations are solved using appropriate matrix techniques and the physical significance of the model is discussed. A number possible classroom exercises are suggested to help…

  3. Do roads reduce painted turtle (Chrysemys picta) populations?

    PubMed

    Dorland, Alexandra; Rytwinski, Trina; Fahrig, Lenore

    2014-01-01

    Road mortality is thought to be a leading cause of turtle population decline. However, empirical evidence of the direct negative effects of road mortality on turtle population abundance is lacking. The purpose of this study was to provide a strong test of the prediction that roads reduce turtle population abundance. While controlling for potentially confounding variables, we compared relative abundance of painted turtles (Chrysemys picta) in 20 ponds in Eastern Ontario, 10 as close as possible to high traffic roads (Road sites) and 10 as far as possible from any major roads (No Road sites). There was no significant effect of roads on painted turtle relative abundance. Furthermore, our data do not support other predictions of the road mortality hypothesis; we observed neither a higher relative frequency of males to females at Road sites than at No Road sites, nor a lower average body size of turtles at Road than at No Road sites. We speculate that, although roads can cause substantial adult mortality in turtles, other factors, such as release from predation on adults and/or nests close to roads counter the negative effect of road mortality in some populations. We suggest that road mitigation for painted turtles can be limited to locations where turtles are forced to migrate across high traffic roads due, for example, to destruction of local nesting habitat or seasonal drying of ponds. This conclusion should not be extrapolated to other species of turtles, where road mortality could have a larger population-level effect than on painted turtles.

  4. Do Roads Reduce Painted Turtle (Chrysemys picta) Populations?

    PubMed Central

    Dorland, Alexandra; Rytwinski, Trina; Fahrig, Lenore

    2014-01-01

    Road mortality is thought to be a leading cause of turtle population decline. However, empirical evidence of the direct negative effects of road mortality on turtle population abundance is lacking. The purpose of this study was to provide a strong test of the prediction that roads reduce turtle population abundance. While controlling for potentially confounding variables, we compared relative abundance of painted turtles (Chrysemys picta) in 20 ponds in Eastern Ontario, 10 as close as possible to high traffic roads (Road sites) and 10 as far as possible from any major roads (No Road sites). There was no significant effect of roads on painted turtle relative abundance. Furthermore, our data do not support other predictions of the road mortality hypothesis; we observed neither a higher relative frequency of males to females at Road sites than at No Road sites, nor a lower average body size of turtles at Road than at No Road sites. We speculate that, although roads can cause substantial adult mortality in turtles, other factors, such as release from predation on adults and/or nests close to roads counter the negative effect of road mortality in some populations. We suggest that road mitigation for painted turtles can be limited to locations where turtles are forced to migrate across high traffic roads due, for example, to destruction of local nesting habitat or seasonal drying of ponds. This conclusion should not be extrapolated to other species of turtles, where road mortality could have a larger population-level effect than on painted turtles. PMID:24858065

  5. 77 FR 8255 - Constitution Road Drum Superfund Site, Atlanta, Dekalb County, GA; Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... ENVIRONMENTAL PROTECTION AGENCY [CERCA-04-2012-3761, FRL-9631-1] Constitution Road Drum Superfund... response costs concerning the Constitution Road Drum Superfund Site located in Atlanta, Dekalb County.... Submit your comments by Site name Constitution Road Drum Superfund Site by one of the following methods...

  6. 77 FR 2981 - Constitution Road Drum Superfund Site; Atlanta, Dekalb County, GA; Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-20

    ... ENVIRONMENTAL PROTECTION AGENCY [CERCA-04-2012-3754, FRL-9619-9] Constitution Road Drum Superfund... settlement for past response costs concerning the Constitution Road Drum Superfund Site located in Atlanta... Ms. Paula V. Painter. Submit your comments by Site name Constitution Road Drum Superfund Site by one...

  7. ARC-1978-AC78-0330-4

    NASA Image and Video Library

    1978-04-18

    Artist: Rick Guidice Space Colonization regenerative life support systems. This concept from a summer study done in 1977 depicts a closed loop life support system for long duration space settlements or space industrialization.

  8. Identifying significant predictors of head-on conflicts on two-lane rural roads using inductive loop detectors data.

    PubMed

    Shariat-Mohaymany, Afshin; Tavakoli-Kashani, Ali; Nosrati, Hadi; Ranjbari, Andisheh

    2011-12-01

    To identify the significant factors that influence head-on conflicts resulting from dangerous overtaking maneuvers on 2-lane rural roads in Iran. A traffic conflict technique was applied to 12 two-lane rural roads in order to investigate the potential situations for accidents to occur and thus to identify the geometric and traffic factors affecting traffic conflicts. Traffic data were collected via the inductive loop detectors installed on these roads, and geometric characteristics were obtained through field observations. Two groups of data were then analyzed independently by Pearson's chi-square test to evaluate their relationship to traffic conflicts. The independent variables were percentage of time spent following (PTSF), percentage of heavy vehicles, directional distribution of traffic (DDT), mean speed, speed standard deviation, section type, road width, longitudinal slope, holiday or workday, and lighting condition. It was indicated that increasing the PTSF, decreasing the percentage of heavy vehicles, increasing the mean speed (up to 75 km/h), increasing DDT in the range of 0 to 60 percent, and decreasing the standard deviation of speed significantly increased the occurrence of traffic conflicts. It was also revealed that traffic conflicts occur more frequently on curve sections and on workdays. The variables road width, slope, and lighting condition were found to have a minor effect on conflict occurrence. To reduce the number of head-on conflicts on the aforementioned roads, some remedial measures are suggested, such as not constructing long "No Passing" zones and constructing passing lanes where necessary; keeping road width at the standard value; constructing roads with horizontal curves and a high radius and using appropriate road markings and overtaking-forbidden signs where it is impossible to modify the radius; providing enough light and installing caution signs/devices on the roads; and intensifying police control and supervision on workdays, especially in peak hours.

  9. Geology and land use in the western part of the Gulf Coast coal-bearing region

    USGS Publications Warehouse

    Warwick, Peter D.; Aubourg, C.E.; Hook, R.W.; SanFilipo, John R.

    2002-01-01

    This map series is a compilation of the outcrop geology in the U.S. Gulf Coast coal region. The maps show the regional geologic setting for primary coal occurrences and detailed geology and historic mining areas.The CD contains ESRI ArcView SHP files of cities, urban areas, historical mines (points and polygons), counties, current mines, 1:100,000 quadrangle outlines of the study area, fossil fuel powerplants, nuclear powerplants, political boundaries, federally managed lands, roads and railroads in the study area, hydrology in the study area (polygons and arcs), geology nomenclature breaks, geological features (faults), and geology. ArcExplorer is included on the CD.

  10. Digital surveying and mapping of forest road network for development of a GIS tool for the effective protection and management of natural ecosystems

    NASA Astrophysics Data System (ADS)

    Drosos, Vasileios C.; Liampas, Sarantis-Aggelos G.; Doukas, Aristotelis-Kosmas G.

    2014-08-01

    In our time, the Geographic Information Systems (GIS) have become important tools, not only in the geosciences and environmental sciences, as well as virtually for all researches that require monitoring, planning or land management. The purpose of this paper was to develop a planning tool and decision making tool using AutoCAD Map software, ArcGIS and Google Earth with emphasis on the investigation of the suitability of forest roads' mapping and the range of its implementation in Greece in prefecture level. Integrating spatial information into a database makes data available throughout the organization; improving quality, productivity, and data management. Also working in such an environment, you can: Access and edit information, integrate and analyze data and communicate effectively. To select desirable information such as forest road network in a very early stage in the planning of silviculture operations, for example before the planning of the harvest is carried out. The software programs that were used were AutoCAD Map for the export in shape files for the GPS data, and ArcGIS in shape files (ArcGlobe), while Google Earth with KML files (Keyhole Markup Language) in order to better visualize and evaluate existing conditions, design in a real-world context and exchange information with government agencies, utilities, and contractors in both CAD and GIS data formats. The automation of the updating procedure and transfer of any files between agencies-departments is one of the main tasks of the integrated GIS-tool among the others should be addressed.

  11. Automated Rendezvous and Capture System Development and Simulation for NASA

    NASA Technical Reports Server (NTRS)

    Roe, Fred D.; Howard, Richard T.; Murphy, Leslie

    2004-01-01

    The United States does not have an Automated Rendezvous and Capture Docking (AR&C) capability and is reliant on manned control for rendezvous and docking of orbiting spacecraft. T h i s reliance on the labor intensive manned interface for control of rendezvous and docking vehicles has a significant impact on the cost of the operation of the International Space Station (ISS) and precludes the use of any U.S. expendable launch capabilities for Space Station resupply. The Marshall Space Flight Center (MSFC) has conducted pioneering research in the development of an automated rendezvous and capture (or docking) (AR&C) system for U.S. space vehicles. This A M C system was tested extensively using hardware-in-the-loop simulations in the Flight Robotics Laboratory, and a rendezvous sensor, the Video Guidance Sensor was developed and successfully flown on the Space Shuttle on flights STS-87 and STS-95, proving the concept of a video- based sensor. Further developments in sensor technology and vehicle and target configuration have lead to continued improvements and changes in AR&C system development and simulation. A new Advanced Video Guidance Sensor (AVGS) with target will be utilized as the primary navigation sensor on the Demonstration of Autonomous Rendezvous Technologies (DART) flight experiment in 2004. Realtime closed-loop simulations will be performed to validate the improved AR&C systems prior to flight.

  12. Soil carbon storage following road removal and timber harvesting in redwood forests

    USGS Publications Warehouse

    Seney, Joseph; Madej, Mary Ann

    2015-01-01

    Soil carbon storage plays a key role in the global carbon cycle and is important for sustaining forest productivity. Removal of unpaved forest roads has the potential for increasing carbon storage in soils on forested terrain as treated sites revegetate and soil properties improve on the previously compacted road surfaces. We compared soil organic carbon (SOC) content at several depths on treated roads to SOC in adjacent second-growth forests and old-growth redwood forests in California, determined whether SOC in the upper 50 cm of soil varies with the type of road treatment, and assessed the relative importance of site-scale and landscape-scale variables in predicting SOC accumulation in treated road prisms and second-growth redwood forests. Soils were sampled at 5, 20, and 50 cm depths on roads treated by two methods (decommissioning and full recontouring), and in adjacent second-growth and old-growth forests in north coastal California. Road treatments spanned a period of 32 years, and covered a range of geomorphic and vegetative conditions. SOC decreased with depth at all sites. Treated roads on convex sites exhibited higher SOC than on concave sites, and north aspect sites had higher SOC than south aspect sites. SOC at 5, 20, and 50 cm depths did not differ significantly between decommissioned roads (treated 18–32 years previous) and fully recontoured roads (treated 2–12 years previous). Nevertheless, stepwise multiple regression models project higher SOC developing on fully recontoured roads in the next few decades. The best predictors for SOC on treated roads and in second-growth forest incorporated aspect, vegetation type, soil depth, lithology, distance from the ocean, years since road treatment (for the road model) and years since harvest (for the forest model). The road model explained 48% of the variation in SOC in the upper 50 cm of mineral soils and the forest model, 54%

  13. The StreamCat Dataset: Accumulated Attributes for NHDPlusV2(Version 2.1) Catchments Riparian Buffer for the Conterminous United States: 2010 US Census Road Density

    EPA Pesticide Factsheets

    This dataset represents the road density within individual, local NHDPlusV2 catchments and upstream, contributing watersheds riparian buffers. Attributes of the landscape layer were calculated for every local NHDPlusV2 catchment and accumulated to provide watershed-level metrics. (See Supplementary Info for Glossary of Terms) This data set is derived from TIGER/Line Files of roads in the conterminous United States. Road density describes how many kilometers of road exist in a square kilometer. A raster was produced using the ArcGIS Line Density Tool to form the landscape layer for analysis. (see Data Sources for links to NHDPlusV2 data and Census Data) The (kilometer of road/square kilometer) was summarized by local catchment and by watershed to produce local catchment-level and watershed-level metrics as a continuous data type (see Data Structure and Attribute Information for a description).

  14. 77 FR 22755 - Foreign-Trade Zone 257-Imperial County, CA; Site Renumbering Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ...); Site 10: (78.11 acres)--Desert Real Estate parcels, Cole Road and Sunset Boulevard, Calexico (formerly part of Site 3b); Site 11: (35.47 acres)--Portico Industrial Park, Cole Road and Enterprise Boulevard, Calexico (formerly part of Site 3b); Site 12: (59.49 acres)--Kloke Tract, Cole Road, Portico Boulevard and...

  15. Chemical characterization and quantitativ e assessment of source-specific health risk of trace metals in PM1.0 at a road site of Delhi, India.

    PubMed

    Prakash, Jai; Lohia, Tarachand; Mandariya, Anil K; Habib, Gazala; Gupta, Tarun; Gupta, Sanjay K

    2018-03-01

    This study presents the concentration of submicron aerosol (PM 1.0 ) collected during November, 2009 to March, 2010 at two road sites near the Indian Institute of Technology Delhi campus. In winter, PM 1.0 composed 83% of PM 2.5 indicating the dominance of combustion activity-generated particles. Principal component analysis (PCA) proved secondary aerosol formation as a dominant process in enhancing aerosol concentration at a receptor site along with biomass burning, vehicle exhaust, road dust, engine and tire tear wear, and secondary ammonia. The non-carcinogenic and excess cancer risk for adults and children were estimated for trace element data set available for road site and at elevated site from another parallel work. The decrease in average hazard quotient (HQ) for children and adults was estimated in following order: Mn > Cr > Ni > Pb > Zn > Cu both at road and elevated site. For children, the mean HQs were observed in safe level for Cu, Ni, Zn, and Pb; however, values exceeded safe limit for Cr and Mn at road site. The average highest hazard index values for children and adults were estimated as 22 and 10, respectively, for road site and 7 and 3 for elevated site. The road site average excess cancer risk (ECR) risk of Cr and Ni was close to tolerable limit (10 -4 ) for adults and it was 13-16 times higher than the safe limit (10 -6 ) for children. The ECR of Ni for adults and children was 102 and 14 times higher at road site compared to elevated site. Overall, the observed ECR values far exceed the acceptable level.

  16. Modeling and simulation of emergent behavior in transportation infrastructure restoration

    USGS Publications Warehouse

    Ojha, Akhilesh; Corns, Steven; Shoberg, Thomas G.; Qin, Ruwen; Long, Suzanna K.

    2018-01-01

    The objective of this chapter is to create a methodology to model the emergent behavior during a disruption in the transportation system and that calculates economic losses due to such a disruption, and to understand how an extreme event affects the road transportation network. The chapter discusses a system dynamics approach which is used to model the transportation road infrastructure system to evaluate the different factors that render road segments inoperable and calculate economic consequences of such inoperability. System dynamics models have been integrated with business process simulation model to evaluate, design, and optimize the business process. The chapter also explains how different factors affect the road capacity. After identifying the various factors affecting the available road capacity, a causal loop diagram (CLD) is created to visually represent the causes leading to a change in the available road capacity and the effects on travel costs when the available road capacity changes.

  17. 76 FR 2112 - Peach Orchard Road Groundwater Plume Site, Augusta, Richmond County, GA; Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... ENVIRONMENTAL PROTECTION AGENCY [Docket EPA-RO4-SFUND-2010-0965 FRL-9251-5] Peach Orchard Road... Orchard Road Groundwater Plume Site located in Augusta, Richmond County, Georgia for publication. DATES..., identified by Docket ID No. EPA-RO4- SFUND-2010-0965 or Site name Peach Orchard Road Groundwater Plume...

  18. Kuiper Airborne Observatory's Telescope Stabilization System: Disturbance Sensitivity Reduction Via Velocity Loop Feedback

    NASA Technical Reports Server (NTRS)

    Lawrence, David P.; Tsui, K. C.; Tucker, John; Mancini, Ronald E. (Technical Monitor)

    1995-01-01

    In July of 1994 the Kuiper Airborne Observatory's (KAO) Telescope Stabilization System (TSS) was upgraded to meet performance goals necessary to view the Shoemaker-Levy 9 comet collision with Jupiter. The KAO is a modified C-141 Aircraft supporting a 36 inch Infrared telescope used to gather and analyze astronomical data. Before the upgrade, the TSS exhibited approximately a 10 arc-second resolution pointing accuracy. The majority of the inaccuracy was attributable to aircraft vibration and wind buffeting entering through the aircraft's telescope door opening; in other words, the TSS was overly sensitive to external disturbances. Because of power limitations and noise requirements, improving the pointing accuracy of the telescope required more sophistication than simply raising the bandwidth as some classical control strategies might suggest. Instead, relationships were developed between the disturbance sensitivity and closed loop transfer functions. These relationships suggested that employing velocity feedback along with an increase in current loop gain would dramatically improve the pointing resolution of the TSS by decreasing the control system's sensitivity to external disturbances. With the implementation of some classical control techniques and the above philosophy, the KAO's TSS's resolution was improved to approximately 2-3 arc-seconds.

  19. Do the surface Fermi arcs in Weyl semimetals survive disorder?

    NASA Astrophysics Data System (ADS)

    Wilson, Justin H.; Pixley, J. H.; Huse, David A.; Refael, Gil; Das Sarma, S.

    2018-06-01

    We theoretically study the topological robustness of the surface physics induced by Weyl Fermi-arc surface states in the presence of short-ranged quenched disorder and surface-bulk hybridization. This is investigated with numerically exact calculations on a lattice model exhibiting Weyl Fermi arcs. We find that the Fermi-arc surface states, in addition to having a finite lifetime from disorder broadening, hybridize with nonperturbative bulk rare states making them no longer bound to the surface (i.e., they lose their purely surface spectral character). Thus, we provide strong numerical evidence that the Weyl Fermi arcs are not topologically protected from disorder. Nonetheless, the surface chiral velocity is robust and survives in the presence of strong disorder, persisting all the way to the Anderson-localized phase by forming localized current loops that live within the localization length of the surface. Thus, the Weyl semimetal is not topologically robust to the presence of disorder, but the surface chiral velocity is.

  20. Plasma Entry from Tail into the Dipolar Magnetosphere During Substorms

    NASA Astrophysics Data System (ADS)

    Haerendel, Gerhard

    Plasma entering the dipolar magnetosphere from the tail has to overcome the obstacle presented by the conductivity enhancements caused by the poleward arc(s). While the arcs move poleward, the plasma proceeds equatorward as testified by the existence of a westward electric field. The arcs break into smaller-scale structures and loops with a tendency of eastward growth and expansion, although the basic driving force is directed earthward/equatorward. The likely reason is that the arc-related conductivity enhancements act as flow barriers and convert normal into shear stresses. The energy derived from the release of the shear stresses and dissipated in the arcs lowers the entropy content of the flux tubes and enables their earthward progression. In addition, poleward jumps of the breakup arcs are quite common. They result from refreshments of the generator plasma by the sequential arrival of flow bursts from the near-Earth neutral line. Once inside the oval, the plasma continues to move equatorward as manifested through north-south aligned auroral forms. Owing to the existence of an inner border of the oval, marked by the Region 2 currents, all flows are eventually diverted sunward.

  1. A transgenic mouse for imaging activity-dependent dynamics of endogenous Arc mRNA in live neurons.

    PubMed

    Das, Sulagna; Moon, Hyungseok C; Singer, Robert H; Park, Hye Yoon

    2018-06-01

    Localized translation plays a crucial role in synaptic plasticity and memory consolidation. However, it has not been possible to follow the dynamics of memory-associated mRNAs in living neurons in response to neuronal activity in real time. We have generated a novel mouse model where the endogenous Arc/Arg3.1 gene is tagged in its 3' untranslated region with stem-loops that bind a bacteriophage PP7 coat protein (PCP), allowing visualization of individual mRNAs in real time. The physiological response of the tagged gene to neuronal activity is identical to endogenous Arc and reports the true dynamics of Arc mRNA from transcription to degradation. The transcription dynamics of Arc in cultured hippocampal neurons revealed two novel results: (i) A robust transcriptional burst with prolonged ON state occurs after stimulation, and (ii) transcription cycles continue even after initial stimulation is removed. The correlation of stimulation with Arc transcription and mRNA transport in individual neurons revealed that stimulus-induced Ca 2+ activity was necessary but not sufficient for triggering Arc transcription and that blocking neuronal activity did not affect the dendritic transport of newly synthesized Arc mRNAs. This mouse will provide an important reagent to investigate how individual neurons transduce activity into spatiotemporal regulation of gene expression at the synapse.

  2. IODP Expedition 351 Izu-Bonin-Mariana Arc Origins: Preliminary Results

    NASA Astrophysics Data System (ADS)

    Ishizuka, O.; Arculus, R. J.; Bogus, K.

    2014-12-01

    Understanding how subduction zones initiate and continental crust forms in intraoceanic arcs requires knowledge of the inception and evolution of a representative intraoceanic arc, such as the Izu-Bonin-Mariana (IBM) Arc system. This can be obtained by exploring regions adjacent to an arc, where unequivocal pre-arc crust overlain by undisturbed arc-derived materials exists. IODP Exp. 351 (June-July 2014) specifically targeted evidence for the earliest evolution of the IBM system following inception. Site U1438 (4711 m water depth) is located in the Amami Sankaku Basin (ASB), west of the Kyushu-Palau Ridge (KPR), a paleo-IBM arc. Primary objectives of Exp. 351 were: 1) determine the nature of the crust and mantle pre-existing the IBM arc; 2) identify and model the process of subduction initiation and initial arc crust formation; 3) determine the compositional evolution of the IBM arc during the Paleogene; 4) establish geophysical properties of the ASB. Seismic reflection profiles indicate a ~1.3 km thick sediment layer overlying ~5.5 km thick igneous crust, presumed to be oceanic. This igneous crust seemed likely to be the basement of the IBM arc. Four holes were cored at Site U1438 spanning the entire sediment section and into basement. The cored interval comprises 5 units: uppermost Unit I is hemipelagic sediment with intercalated ash layers, presumably recording explosive volcanism mainly from the Ryukyu and Kyushu arcs; Units II and III host a series of volcaniclastic gravity-flow deposits, likely recording the magmatic history of the IBM Arc from arc initiation until 25 Ma; Siliceous pelagic sediment (Unit IV) underlies these deposits with minimal coarse-grained sediment input and may pre-date arc initiation. Sediment-basement contact occurs at 1461 mbsf. A basaltic lava flow section dominantly composed of plagioclase and clinopyroxene with rare chilled margins continues to the bottom of the Site (1611 mbsf). The expedition successfully recovered pre-IBM Arc basement, a volcanic and geologic record spanning pre-Arc, Arc initiation to remnant Arc stages, which permits testing for subduction initiation and subsequent Arc evolution.

  3. Enthalpy By Energy Balance for Aerodynamic Heating Facility at NASA Ames Research Center Arc Jet Complex

    NASA Technical Reports Server (NTRS)

    Hightower, T. Mark; MacDonald, Christine L.; Martinez, Edward R.; Balboni, John A.; Anderson, Karl F.; Arnold, Jim O. (Technical Monitor)

    2002-01-01

    The NASA Ames Research Center (ARC) Arc Jet Facilities' Aerodynamic Heating Facility (AHF) has been instrumented for the Enthalpy By Energy Balance (EB2) method. Diagnostic EB2 data is routinely taken for all AHF runs. This paper provides an overview of the EB2 method implemented in the AHF. The chief advantage of the AHF implementation over earlier versions is the non-intrusiveness of the instruments used. For example, to measure the change in cooling water temperature, thin film 1000 ohm Resistance Temperature Detectors (RTDs) are used with an Anderson Current Loop (ACL) as the signal conditioner. The ACL with 1000 ohm RTDs allows for very sensitive measurement of the increase in temperature (Delta T) of the cooling water to the arc heater, which is a critical element of the EB2 method. Cooling water flow rates are measured with non-intrusive ultrasonic flow meters.

  4. Compensated control loops for a 30-cm ion thruster

    NASA Technical Reports Server (NTRS)

    Robson, R. R.

    1976-01-01

    The vaporizer dynamic control characteristics of a 30-cm diameter mercury ion thruster were determined by operating the thruster in an open loop steady state mode and then introducing a small sinusoidal signal on the main, cathode, or neutralizer vaporizer current and observing the response of the beam current, discharge voltage, and neutralizer keeper voltage, respectively. This was done over a range of frequencies and operating conditions. From these data, Bode plots for gain and phase were made and mathematical models were obtained. The Bode plots and mathematical models were analyzed for stability and appropriate compensation networks determined. The compensated control loops were incorporated into a power processor and operated with a thruster. The time responses of the compensated loops to changes in set points and recovery from arc conditions are presented.

  5. Real-Time Imaging Reveals Properties of Glutamate-Induced Arc/Arg 3.1 Translation in Neuronal Dendrites.

    PubMed

    Na, Youn; Park, Sungjin; Lee, Changhee; Kim, Dong-Kyu; Park, Joo Min; Sockanathan, Shanthini; Huganir, Richard L; Worley, Paul F

    2016-08-03

    The immediate early gene Arc (also Arg3.1) produces rapid changes in synaptic properties that are linked to de novo translation. Here we develop a novel translation reporter that exploits the rapid maturation and "flash" kinetics of Gaussia luciferase (Gluc) to visualize Arc translation. Following glutamate stimulation, discrete Arc-Gluc bioluminescent flashes representing sites of de novo translation are detected within 15 s at distributed sites in dendrites, but not spines. Flashes are episodic, lasting ∼20 s, and may be unitary or repeated at ∼minute intervals at the same sites. Analysis of flash amplitudes suggests they represent the quantal product of one or more polyribosomes, while inter-flash intervals appear random, suggesting they arise from a stochastic process. Surprisingly, glutamate-induced translation is dependent on Arc open reading frame. Combined observations support a model in which stalled ribosomes are reactivated to rapidly generate Arc protein. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Built environment analysis for road traffic hotspot locations in Moshi, Tanzania.

    PubMed

    Waldon, Meredith; Ibingira, Treasure Joelson; de Andrade, Luciano; Mmbaga, Blandina T; Vissoci, João Ricardo N; Mvungi, Mark; Staton, Catherine A

    2018-02-08

    Road traffic injuries (RTIs) cause significant morbidity and mortality in low- and middle-income countries. Investigation of high risk areas for RTIs is needed to guide improvements. This study provides built environmental analysis of road traffic crash hotspots within Moshi, Tanzania. Spatial analysis of police data identified 36 hotspots. Qualitative comparative analysis revealed 40% of crash sites were on local roads without night lighting and increased motorcycle density. Paved narrow roads represented 26% of hotspots and 13% were unpaved roads with uneven roadsides. Roadside unevenness was more predominate in low risk [n = 19, (90.5%)] than high risk sites [n = 7 (46.7%)]. Both low [n = 6 (28.6%)] and high risk [n = 1 (6.7%)] sites had minimal signage. All sites had informal pedestrian pathways. Little variability between risk sites suggests hazardous conditions are widespread. Findings suggest improvement in municipal infrastructure, signage and enforcement is needed to reduce RTI burden.

  7. 76 FR 21330 - Lynn Canal/Icy Straits Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ..., 8510 Mendenhall Loop Road, Juneau, Alaska 99801, or electronically to Debra Robinson, RAC Coordinator at [email protected] . FOR FURTHER INFORMATION CONTACT: Debra Robinson, RAC Coordinator Juneau...

  8. Sensor Fusion to Estimate the Depth and Width of the Weld Bead in Real Time in GMAW Processes

    PubMed Central

    Sampaio, Renato Coral; Vargas, José A. R.

    2018-01-01

    The arc welding process is widely used in industry but its automatic control is limited by the difficulty in measuring the weld bead geometry and closing the control loop on the arc, which has adverse environmental conditions. To address this problem, this work proposes a system to capture the welding variables and send stimuli to the Gas Metal Arc Welding (GMAW) conventional process with a constant voltage power source, which allows weld bead geometry estimation with an open-loop control. Dynamic models of depth and width estimators of the weld bead are implemented based on the fusion of thermographic data, welding current and welding voltage in a multilayer perceptron neural network. The estimators were trained and validated off-line with data from a novel algorithm developed to extract the features of the infrared image, a laser profilometer was implemented to measure the bead dimensions and an image processing algorithm that measures depth by making a longitudinal cut in the weld bead. These estimators are optimized for embedded devices and real-time processing and were implemented on a Field-Programmable Gate Array (FPGA) device. Experiments to collect data, train and validate the estimators are presented and discussed. The results show that the proposed method is useful in industrial and research environments. PMID:29570698

  9. Sensor Fusion to Estimate the Depth and Width of the Weld Bead in Real Time in GMAW Processes.

    PubMed

    Bestard, Guillermo Alvarez; Sampaio, Renato Coral; Vargas, José A R; Alfaro, Sadek C Absi

    2018-03-23

    The arc welding process is widely used in industry but its automatic control is limited by the difficulty in measuring the weld bead geometry and closing the control loop on the arc, which has adverse environmental conditions. To address this problem, this work proposes a system to capture the welding variables and send stimuli to the Gas Metal Arc Welding (GMAW) conventional process with a constant voltage power source, which allows weld bead geometry estimation with an open-loop control. Dynamic models of depth and width estimators of the weld bead are implemented based on the fusion of thermographic data, welding current and welding voltage in a multilayer perceptron neural network. The estimators were trained and validated off-line with data from a novel algorithm developed to extract the features of the infrared image, a laser profilometer was implemented to measure the bead dimensions and an image processing algorithm that measures depth by making a longitudinal cut in the weld bead. These estimators are optimized for embedded devices and real-time processing and were implemented on a Field-Programmable Gate Array (FPGA) device. Experiments to collect data, train and validate the estimators are presented and discussed. The results show that the proposed method is useful in industrial and research environments.

  10. A new supernova remnant candidate in the UWIFE [Fe II] line survey

    NASA Astrophysics Data System (ADS)

    Kim, Yesol; Koo, Bon-Chul

    2016-06-01

    We report the discovery of a new supernova remnant (SNR) candidate in the narrow-band [Fe II] 1.644 um line imaging survey UWIFE (UKIRT Widefield Infrared Survey for Fe). UWIFE covers the first quadrant of the Galactic plane (7degrees < l < 62degrees, |b| < 1.5degrees), and, by visual inspection, we have found ~300 extended Ionized Fe objects (IFOs) in the survey area. Most of IFOs are associated with SNRs, young stellar objects, HII regions, and planetary nebulae. But about 12% of IFOs are not associated with any known astronomical objects, and the SNR candidate, IFO J183740.829-061452.41 (hereafter IFO J183740) is one of those. IFO J183740 is a 6`-long, faint, arc-like filament with small-scale irregular structures. It appears to be a portion of a circular loop, but the rest of the loop is not seen in [Fe II] emission. It is found to coincide with a well-defined radio continuum arc. The radio arc has a complicated morphology, and IFO J183740 coincides with the bright inner part of the radio arc. Hydrogen recombination lines have been detected toward the radio arc from low-resolution surveys, so it has been known as an HII region (G25.8+0.2) at a kinematic distance of 6.5 kpc. But the inside of this radio arc is filled with soft X-rays, while, just outside the arc to the north, there is hard X-ray nebula harboring a young pulsar. Therefore, the nature of this arc-like structure seen in radio and [Fe II] emission is uncertain. In this presentation, we present the results of follow-up spectroscopic study of IFO J183740 using IGRINS (Immersion Grating Infrared Spectrograph) which is high spectral resolution (R~40,000) spectrograph covering H and K-bands, simultaneously. We have found that the [Fe II] filaments are both spatially and kinematically distinct from the HII filaments. The intensity ratios of [Fe II] to Brγ lines suggest that the HII filaments are photoionized while the [Fe II] filaments are shock-ionized, which supports the SNR origin for IFO J183740. We discuss the association of IFO J183740 with other sources in the region.

  11. Source diagnostics of polycyclic aromatic hydrocarbons in urban road runoff, dust, rain and canopy throughfall.

    PubMed

    Zhang, Wei; Zhang, Shucai; Wan, Chao; Yue, Dapan; Ye, Youbin; Wang, Xuejun

    2008-06-01

    Diagnostic ratios and multivariate analysis were utilized to apportion polycyclic aromatic hydrocarbon (PAH) sources for road runoff, road dust, rain and canopy throughfall based on samples collected in an urban area of Beijing, China. Three sampling sites representing vehicle lane, bicycle lane and branch road were selected. For road runoff and road dust, vehicular emission and coal combustion were identified as major sources, and the source contributions varied among the sampling sites. For rain, three principal components were apportioned representing coal/oil combustion (54%), vehicular emission (34%) and coking (12%). For canopy throughfall, vehicular emission (56%), coal combustion (30%) and oil combustion (14%) were identified as major sources. Overall, the PAH's source for road runoff mainly reflected that for road dust. Despite site-specific sources, the findings at the study area provided a general picture of PAHs sources for the road runoff system in urban area of Beijing.

  12. 77 FR 52067 - NASA Advisory Council; Commercial Space Committee; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [12-069] NASA Advisory Council; Commercial Space.... DATES: Tuesday, September 18, 2012, 11:45 a.m.-5:30 p.m.; Local Time. ADDRESSES: NASA Ames Research Center (ARC), The Showroom, Building M-3, NASA Ames Conference Center, 500 Severyns Road, NASA Research...

  13. Magnetic-field-induced irreversible antiferromagnetic-ferromagnetic phase transition around room temperature in as-cast Sm-Co based SmCo7-xSix alloys

    NASA Astrophysics Data System (ADS)

    Feng, D. Y.; Zhao, L. Z.; Liu, Z. W.

    2016-04-01

    A magnetic-field-induced irreversible metamagnetic phase transition from antiferro- to ferromagnetism, which leads to an anomalous initial-magnetization curve lying outside the magnetic hysteresis loop, is reported in arc-melted SmCo7-xSix alloys. The transition temperatures are near room temperature, much higher than other compounds with similar initial curves. Detailed investigation shows that this phenomenon is dependent on temperature, magnetic field and Si content and shows some interesting characteristics. It is suggested that varying interactions between the Sm and Co layers in the crystal are responsible for the formation of a metastable AFM structure, which induces the anomalous phenomenon in as-cast alloys. The random occupation of 3g sites by Si and Co atoms also has an effect on this phenomenon.

  14. DNA looping by FokI: the impact of synapse geometry on loop topology at varied site orientations

    PubMed Central

    Rusling, David A.; Laurens, Niels; Pernstich, Christian; Wuite, Gijs J. L.; Halford, Stephen E.

    2012-01-01

    Most restriction endonucleases, including FokI, interact with two copies of their recognition sequence before cutting DNA. On DNA with two sites they act in cis looping out the intervening DNA. While many restriction enzymes operate symmetrically at palindromic sites, FokI acts asymmetrically at a non-palindromic site. The directionality of its sequence means that two FokI sites can be bridged in either parallel or anti-parallel alignments. Here we show by biochemical and single-molecule biophysical methods that FokI aligns two recognition sites on separate DNA molecules in parallel and that the parallel arrangement holds for sites in the same DNA regardless of whether they are in inverted or repeated orientations. The parallel arrangement dictates the topology of the loop trapped between sites in cis: the loop from inverted sites has a simple 180° bend, while that with repeated sites has a convoluted 360° turn. The ability of FokI to act at asymmetric sites thus enabled us to identify the synapse geometry for sites in trans and in cis, which in turn revealed the relationship between synapse geometry and loop topology. PMID:22362745

  15. Advancing viral RNA structure prediction: measuring the thermodynamics of pyrimidine-rich internal loops

    PubMed Central

    Phan, Andy; Mailey, Katherine; Saeki, Jessica; Gu, Xiaobo

    2017-01-01

    Accurate thermodynamic parameters improve RNA structure predictions and thus accelerate understanding of RNA function and the identification of RNA drug binding sites. Many viral RNA structures, such as internal ribosome entry sites, have internal loops and bulges that are potential drug target sites. Current models used to predict internal loops are biased toward small, symmetric purine loops, and thus poorly predict asymmetric, pyrimidine-rich loops with >6 nucleotides (nt) that occur frequently in viral RNA. This article presents new thermodynamic data for 40 pyrimidine loops, many of which can form UU or protonated CC base pairs. Uracil and protonated cytosine base pairs stabilize asymmetric internal loops. Accurate prediction rules are presented that account for all thermodynamic measurements of RNA asymmetric internal loops. New loop initiation terms for loops with >6 nt are presented that do not follow previous assumptions that increasing asymmetry destabilizes loops. Since the last 2004 update, 126 new loops with asymmetry or sizes greater than 2 × 2 have been measured. These new measurements significantly deepen and diversify the thermodynamic database for RNA. These results will help better predict internal loops that are larger, pyrimidine-rich, and occur within viral structures such as internal ribosome entry sites. PMID:28213527

  16. Insights into the Early to Late Oligocene Izu-Bonin Mariana Arc Magmatic History from Volcanic Minerals and Glass within Volcaniclastic Sediments of IODP Site U1438 and DSDP Site 296

    NASA Astrophysics Data System (ADS)

    Samajpati, E.; Hickey-Vargas, R.

    2017-12-01

    The Kyushu-Palau Ridge (KPR) is a remnant of the early Izu-Bonin-Mariana (IBM) island arc, separated by arc rifting and seafloor spreading. We examine and compare volcanic materials from two sites where the transition from IBM arc building to rifting is well sampled: DSDP Site 296 on the northern KPR crest, and recent IODP Site U1438 in the adjacent Amami-Sankaku basin to the west. The purpose of the study is to understand the origin and depositional regime of volcaniclastic sediments during the arc rifting stage. Site 1438 sedimentary Unit II and the upper part of Unit III (300 and 453 mbsf) correlate in time with sedimentary Units 1G and 2 of DSDP Site 296 (160 and 300 mbsf). The upper part of Site U1438 Unit III and Site 296 Unit 2 consist of early to late Oligocene coarse volcaniclastic sedimentary rocks. These are overlain by late Oligocene nannofossil chalks with volcanic sand and ash-rich layers at Site 296 Unit 1G, and tuffaceous silt, sand, siltstone and sandstone at Site 1438 Unit II. The chemical composition of volcanic glass shards, pyroxenes with melt inclusions and amphiboles separated from volcaniclastic sediments were analyzed by EPMA and LA-ICPMS. Glasses are found at Site 296 only, range from medium-K basalt to rhyolite and have trace element patterns typical of arc volcanics. Clinopyroxene and orthopyroxene are found as detrital grains in sediments from both sites. Mg-numbers range from 58 to 94. Interestingly, the alumina content of pyroxene grain populations from both sites increase and then decrease with decreasing Mg-number. This probably reflects control of Al contents in magma and pyroxene by suppressed plagioclase saturation, which apparently was a consistent feature of KPR volcanoes. Melt-inclusions within the pyroxenes are typically small (30-50 microns) and have similar chemical compositions within one grain. The melt inclusions range from basalt to rhyolite with moderate alkali content. Amphibole is more prevalent in late Oligocene sequences and is mainly magnesiohornblende, with some more alkali-rich grains. Mantle normalized trace element patterns of the amphiboles show depletion in LREE and HFSE (Nb, Zr and Hf) and flat MREE and HREE. Downcore mineralogical and geochemical changes at these sites will be interpreted in the context of arc evolution.

  17. Double Arc Instability in the Solar Corona

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ishiguro, N.; Kusano, K., E-mail: n-ishiguro@isee.nagoya-u.ac.jp

    The stability of the magnetic field in the solar corona is important for understanding the causes of solar eruptions. Although various scenarios have been suggested to date, the tether-cutting reconnection scenario proposed by Moore et al. is one of the widely accepted models to explain the onset process of solar eruptions. Although the tether-cutting reconnection scenario proposes that the sigmoidal field formed by internal reconnection is the magnetic field in the pre-eruptive state, the stability of the sigmoidal field has not yet been investigated quantitatively. In this paper, in order to elucidate the stability problem of the pre-eruptive state, wemore » developed a simple numerical analysis in which the sigmoidal field is modeled by a double arc electric current loop and its stability is analyzed. As a result, we found that the double arc loop is more easily destabilized than the axisymmetric torus, and it becomes unstable even if the external field does not decay with altitude, which is in contrast to the axisymmetric torus instability. This suggests that tether-cutting reconnection may well work as the onset mechanism of solar eruptions, and if so, the critical condition for eruption under a certain geometry may be determined by a new type of instability rather than by the torus instability. Based on them, we propose a new type of instability called double arc instability (DAI). We discuss the critical conditions for DAI and derive a new parameter κ , defined as the product of the magnetic twist and the normalized flux of the tether-cutting reconnection.« less

  18. New Estimates of Crustal Velocity in the Solomon Islands

    NASA Astrophysics Data System (ADS)

    Phillips, D. A.; Bevis, M.; Taylor, F. W.; Papabatu, A. K.; Basi, S.; Kendrick, E.

    2002-12-01

    We present crustal velocity estimates derived from a dense GPS network in the western Solomon Islands. Initial crustal motion estimates reported by Tregoning et al. (1998) showed convergence between the Australian Plate and the Solomon Arc at the San Cristobal Trench. Active deformation between the Pacific Plate and the Solomon Arc block was also detected. In 1997, we established a continuous GPS (CGPS) site on Guadalcanal and five rover GPS sites in the New Georgia Group. The Guadalcanal site was short-lived due to vandalism so we established a new CGPS site in the New Georgia Group in 1999. The original rover sites were re-occupied in 1999 and 2001. We have analyzed this four-year time series using GAMIT/GLOBK software. Our measurements show convergence with the Australian Plate as well as motion between the Solomon Arc and the Pacific Plate. Possible intra-arc deformation is also observed. Regional tectonic interpretations based upon our GPS measurements and other data will be discussed.

  19. Dirac node arcs in PtSn 4

    DOE PAGES

    Wu, Yun; Wang, Lin -Lin; Mun, Eundeok; ...

    2016-04-04

    In topological quantum materials 1,2,3 the conduction and valence bands are connected at points or along lines in the momentum space. A number of studies have demonstrated that several materials are indeed Dirac/Weyl semimetals 4,5,6,7,8. However, there is still no experimental confirmation of materials with line nodes, in which the Dirac nodes form closed loops in the momentum space 2,3. Here we report the discovery of a novel topological structure—Dirac node arcs—in the ultrahigh magnetoresistive material PtSn 4 using laser-based angle-resolved photoemission spectroscopy data and density functional theory calculations. Unlike the closed loops of line nodes, the Dirac node arcmore » structure arises owing to the surface states and resembles the Dirac dispersion in graphene that is extended along a short line in the momentum space. Here, we propose that this reported Dirac node arc structure is a novel topological state that provides an exciting platform for studying the exotic properties of Dirac fermions.« less

  20. A transgenic mouse for imaging activity-dependent dynamics of endogenous Arc mRNA in live neurons

    PubMed Central

    2018-01-01

    Localized translation plays a crucial role in synaptic plasticity and memory consolidation. However, it has not been possible to follow the dynamics of memory-associated mRNAs in living neurons in response to neuronal activity in real time. We have generated a novel mouse model where the endogenous Arc/Arg3.1 gene is tagged in its 3′ untranslated region with stem-loops that bind a bacteriophage PP7 coat protein (PCP), allowing visualization of individual mRNAs in real time. The physiological response of the tagged gene to neuronal activity is identical to endogenous Arc and reports the true dynamics of Arc mRNA from transcription to degradation. The transcription dynamics of Arc in cultured hippocampal neurons revealed two novel results: (i) A robust transcriptional burst with prolonged ON state occurs after stimulation, and (ii) transcription cycles continue even after initial stimulation is removed. The correlation of stimulation with Arc transcription and mRNA transport in individual neurons revealed that stimulus-induced Ca2+ activity was necessary but not sufficient for triggering Arc transcription and that blocking neuronal activity did not affect the dendritic transport of newly synthesized Arc mRNAs. This mouse will provide an important reagent to investigate how individual neurons transduce activity into spatiotemporal regulation of gene expression at the synapse.

  1. 78 FR 48809 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-12

    ... Road Sanitary Landfill (MRSL) Superfund Site AGENCY: Environmental Protection Agency (EPA). ACTION... Road Sanitary Landfill Superfund Site (MRSL or Site) is located at 3300 Mosley Road between NE 23rd and... Oklahoma State Department of Health (OSDH) (now Oklahoma Department of Environmental Quality) as a sanitary...

  2. A national-scale review of air pollutant concentrations measured in the U.S. near-road monitoring network during 2014 and 2015

    NASA Astrophysics Data System (ADS)

    DeWinter, Jennifer L.; Brown, Steven G.; Seagram, Annie F.; Landsberg, Karin; Eisinger, Douglas S.

    2018-06-01

    In 2010, the U.S. Environmental Protection Agency (EPA) revised the National Ambient Air Quality Standards (NAAQS) for NO2 to include a primary health-based standard for hourly NO2, and required air quality monitoring next to major roadways in urban areas in the U.S. Requirements for near-road measurements also include carbon monoxide (CO) and particulate matter smaller than 2.5 μm in diameter (PM2.5). We performed a national-scale assessment of air pollutants measured at 81 sites in the near-road environment during the first two years (2014 and 2015) of the new measurement program. We evaluated how concentrations at these locations compared to the NAAQS, to concentrations measured at other sites within the same urban areas, and when considering their site characteristics (distance of monitor to road, traffic volume, and meteorology). We also estimated the contribution of emissions from adjacent roadways at each near-road site to the PM2.5 concentrations above the local urban background concentrations, i.e., the near-road "increment." Hourly values of CO reached a maximum of 4.8 ppm across 31 sites in 2014 and 9.6 ppm across 47 sites in 2015, and were well below the NAAQS levels for both the 1-hr (35 ppm) and 8-hr (9 ppm) standards. Hourly concentrations of near-road NO2 reached 258 ppb across 40 sites in 2014; however, there were only two occurrences of a daily 1-hr maximum NO2 concentration above 100 ppb (the level of the hourly NO2 standard). In 2015, hourly concentrations of near-road NO2, monitored at 61 sites in 55 urban areas, reached 154 ppb. Only 0.0015% (n = 5) of hourly NO2 observations in 2015 exceeded 100 ppb. The highest annual NO2 average recorded in 2015 (29.9 ppb) occurred at the Ontario site located along I-10 in the Los Angeles, California, area and was below the level of the NO2 annual standard (53 ppb); in 2014, the highest annual mean NO2 was also observed in Los Angeles at the Anaheim site (27.1 ppb). In 2014, sites in Cincinnati, Indianapolis, and Louisville recorded annual average PM2.5 concentrations at or above 12 μg/m3 (the level of the annual standard). There were 15 occurrences in 2014 of 24-hr PM2.5 concentrations above the NAAQS level of 35 μg/m3. Annual average PM2.5 exceeded 12 μg/m3 at near-road sites in five urban areas in 2015, and there were 33 days across 12 near-road locations with 24-hr PM2.5 concentrations above 35 μg/m3. Across the near-road monitoring network, annual average PM2.5 concentrations did not have a significant relationship with traffic volume or distance between the monitor and the adjacent roadway; rather, variations in PM2.5 were mostly driven by urban-scale PM2.5, with a typically small "increment" above urban-scale concentrations due to a site's proximity to the roadway. We estimated this increment, i.e., the difference between near-road PM2.5 concentrations and the concentrations at sites in the urban area of each near-road monitor, to be on average 1.2 μg/m3 (σ = 0.3 μg/m3), with a range of -1.2 μg/m3 to 3.1 μg/m3 across the 26 sites (four of which had a negative increment). The near-road increment is on average 13% of the near-road PM2.5, and 15% of the near-road PM2.5 for sites within 20 m of the roadway.

  3. AmeriFlux US-ARc ARM Southern Great Plains control site- Lamont

    DOE Data Explorer

    Torn, Margaret [Lawrence Berkeley National Laboratory

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site US-ARc ARM Southern Great Plains control site- Lamont. Site Description - The ARM SGP Control site is located in the native tallgrass prairies of the USDA Grazinglands Research Laboratory near El Reno, OK. One of two adjacent 35 ha plots with identical towers, measurements at the US-ARc unburned plot are used as the experimental control. The second plot, US-Arb, was burned on 2005/03/08. Measurement comparisons between the control and burn plot are used to address questions regarding the effects of burning activities on carbon fluxes. The region evaded burning activities for at least 15 years. Current disturbances consist of only light grazing activities.

  4. Bright Loops at 171

    NASA Technical Reports Server (NTRS)

    2007-01-01

    STEREO was able to capture bright loops in exquisite detail as they were arcing above an active region (May 26, 2007) over an 18 hour period. What we are actually seeing are charged particles spinning along magnetic field lines that extend above the Sun's surface. Active regions are areas of intense magnetic activity and often the source of solar storms. In fact, the clip ends with a flourish in which a small coronal mass ejection (CME) blows out into space. This is from the STEREO Ahead spacecraft at the 171 Angstroms wavelength in extreme ultraviolet light.

  5. 23. Surrender interview site, showing Pemberton Avenue concrete slab road ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Surrender interview site, showing Pemberton Avenue concrete slab road type with gutter (asphalt construction typical on Union and Confederate Avenues), view to the sw. - Vicksburg National Military Park Roads & Bridges, Vicksburg, Warren County, MS

  6. 75 FR 38500 - Notice of Availability of Draft Environmental Impact Statement for the Proposed Folsom South of U...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... Water Facility Alternative--Raw Water Conveyance--Grant Line Road Alignment and On- site WTP; (3) Off-site Water Facility Alternative 1--Raw Water Conveyance--Grant Line Road Alignment and White Rock WTP; (4) Off-site Water Facility Alternative 1A--Raw Water Conveyance--Grant Line Road Route Variation...

  7. Paleoceanography/climate and taphonomy at intermediate water depth in the Subtropical Western North Pacific Ocean over the last 1 Ma from IODP Exp 350 Sites U1436C and U1437B, Izu arc area.

    NASA Astrophysics Data System (ADS)

    Vautravers, Maryline

    2015-04-01

    IODP Expedition 350 Site U1436C lies in the western part of the Izu fore arc basin, ~60 km east of the arc front volcano Aogashima, at 1776 m water depth. This site is a technical hole (only a 150 m long record) for a potential future deep drilling by Chikyu. Site U1437 is located in the Izu rear arc, ~90 km west of the arc front volcanoes Myojinsho and Myojin Knoll, at 2117 m water depth. At this site in order to study the evolution of the IZU rear arc crust we recovered a 1800 meter long sequence of mud and volcaniclastic sediments. These sites provide a rich and well-preserved record of volcanic eruptions within the area of the Izu Bonin-Arc. However, the material recovered, mostly mud with ash containing generally abundant planktonic foraminifera, can support additional paleoceanographic goals in an area affected by the Kuroshio Current. Also, the hydrographic divide created by the Izu rise provides a rare opportunity to gain some insight into the operation of the global intermediate circulation. The Antarctic Intermediate Water Mass is more influential at the depth of U1437B in the West and the North Pacific Intermediate Water at Site U1436C to the East. We analyzed 460 samples recovered at Sites U1436C and U1437B for a quantitative planktonic foraminifer study, and also for carbonate preservation indices, including: shell weight, percent planktonic foraminifera fragments planktonic foraminifer concentrations, various faunal proxies, and benthic/planktonic ratio. We measured the stable isotopes for a similar number of samples using the thermocline dwelling Neogloboquadrina dutertrei. The dataset presented here covers the last 1 Ma at Site U1437B and 0.9 Ma at Site U1436C. The age models for the two sites are largely established through stable isotope stratigraphy (this study). On their respective age models we evidence based on polar/subpolar versus subtropical faunal assemblages changes qualitative surface water temperature variations recording the changing influences in the Kuroshio/Oyashio currents at orbital time scales over the last 1 Ma. However, the 2 main findings are i.) that of the intense and pervasive carbonate dissolution at such an intermediate water depth, especially during interglacials, and in particular at site U1436C, and ii.) the good and improving carbonate preservation at Site U1437B during glacials, particularly in the upper part of the record.

  8. Advancing viral RNA structure prediction: measuring the thermodynamics of pyrimidine-rich internal loops.

    PubMed

    Phan, Andy; Mailey, Katherine; Saeki, Jessica; Gu, Xiaobo; Schroeder, Susan J

    2017-05-01

    Accurate thermodynamic parameters improve RNA structure predictions and thus accelerate understanding of RNA function and the identification of RNA drug binding sites. Many viral RNA structures, such as internal ribosome entry sites, have internal loops and bulges that are potential drug target sites. Current models used to predict internal loops are biased toward small, symmetric purine loops, and thus poorly predict asymmetric, pyrimidine-rich loops with >6 nucleotides (nt) that occur frequently in viral RNA. This article presents new thermodynamic data for 40 pyrimidine loops, many of which can form UU or protonated CC base pairs. Uracil and protonated cytosine base pairs stabilize asymmetric internal loops. Accurate prediction rules are presented that account for all thermodynamic measurements of RNA asymmetric internal loops. New loop initiation terms for loops with >6 nt are presented that do not follow previous assumptions that increasing asymmetry destabilizes loops. Since the last 2004 update, 126 new loops with asymmetry or sizes greater than 2 × 2 have been measured. These new measurements significantly deepen and diversify the thermodynamic database for RNA. These results will help better predict internal loops that are larger, pyrimidine-rich, and occur within viral structures such as internal ribosome entry sites. © 2017 Phan et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

  9. 76 FR 30906 - Foreign-Trade Zone 277-Western Maricopa County, AZ; Application for Reorganization Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ...'s standard 2,000-acre activation limit for a general-purpose zone project. The application was... Pointe Business Park, Waddell Road and Litchfield Road, Surprise; Site 3 (235 acres)--within the 1,600-acre Palm Valley 303 Industrial Park, Camelback Road and State Road 303, Goodyear; and, Site 4 (320...

  10. 77 FR 66979 - Ellis Road/American Electric Corporation, Jacksonville, Duval County, FL, Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-08

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL 9750-7; CERCLA-04-2010-3768] Ellis Road/American Electric... conduct sampling, perform a clean-up and compromise cost with over 80 settling parties at the Ellis Road.... Submit your comments by Site name Ellis Road/American Electric Corporation Site by one of the following...

  11. Site conditions related to erosion on logging roads

    Treesearch

    R. M. Rice; J. D. McCashion

    1985-01-01

    Synopsis - Data collected from 299 road segments in northwestern California were used to develop and test a procedure for estimating and managing road-related erosion. Site conditions and the design of each segment were described by 30 variables. Equations developed using 149 of the road segments were tested on the other 150. The best multiple regression equation...

  12. An expert-based approach to forest road network planning by combining Delphi and spatial multi-criteria evaluation.

    PubMed

    Hayati, Elyas; Majnounian, Baris; Abdi, Ehsan; Sessions, John; Makhdoum, Majid

    2013-02-01

    Changes in forest landscapes resulting from road construction have increased remarkably in the last few years. On the other hand, the sustainable management of forest resources can only be achieved through a well-organized road network. In order to minimize the environmental impacts of forest roads, forest road managers must design the road network efficiently and environmentally as well. Efficient planning methodologies can assist forest road managers in considering the technical, economic, and environmental factors that affect forest road planning. This paper describes a three-stage methodology using the Delphi method for selecting the important criteria, the Analytic Hierarchy Process for obtaining the relative importance of the criteria, and finally, a spatial multi-criteria evaluation in a geographic information system (GIS) environment for identifying the lowest-impact road network alternative. Results of the Delphi method revealed that ground slope, lithology, distance from stream network, distance from faults, landslide susceptibility, erosion susceptibility, geology, and soil texture are the most important criteria for forest road planning in the study area. The suitability map for road planning was then obtained by combining the fuzzy map layers of these criteria with respect to their weights. Nine road network alternatives were designed using PEGGER, an ArcView GIS extension, and finally, their values were extracted from the suitability map. Results showed that the methodology was useful for identifying road that met environmental and cost considerations. Based on this work, we suggest future work in forest road planning using multi-criteria evaluation and decision making be considered in other regions and that the road planning criteria identified in this study may be useful.

  13. A statistical analysis of the impact of advertising signs on road safety.

    PubMed

    Yannis, George; Papadimitriou, Eleonora; Papantoniou, Panagiotis; Voulgari, Chrisoula

    2013-01-01

    This research aims to investigate the impact of advertising signs on road safety. An exhaustive review of international literature was carried out on the effect of advertising signs on driver behaviour and safety. Moreover, a before-and-after statistical analysis with control groups was applied on several road sites with different characteristics in the Athens metropolitan area, in Greece, in order to investigate the correlation between the placement or removal of advertising signs and the related occurrence of road accidents. Road accident data for the 'before' and 'after' periods on the test sites and the control sites were extracted from the database of the Hellenic Statistical Authority, and the selected 'before' and 'after' periods vary from 2.5 to 6 years. The statistical analysis shows no statistical correlation between road accidents and advertising signs in none of the nine sites examined, as the confidence intervals of the estimated safety effects are non-significant at 95% confidence level. This can be explained by the fact that, in the examined road sites, drivers are overloaded with information (traffic signs, directions signs, labels of shops, pedestrians and other vehicles, etc.) so that the additional information load from advertising signs may not further distract them.

  14. Partial Arc Curvilinear Direct Drive Servomotor

    NASA Technical Reports Server (NTRS)

    Sun, Xiuhong (Inventor)

    2014-01-01

    A partial arc servomotor assembly having a curvilinear U-channel with two parallel rare earth permanent magnet plates facing each other and a pivoted ironless three phase coil armature winding moves between the plates. An encoder read head is fixed to a mounting plate above the coil armature winding and a curvilinear encoder scale is curved to be co-axis with the curvilinear U-channel permanent magnet track formed by the permanent magnet plates. Driven by a set of miniaturized power electronics devices closely looped with a positioning feedback encoder, the angular position and velocity of the pivoted payload is programmable and precisely controlled.

  15. Welding. FOS: Fundamentals of Service.

    ERIC Educational Resources Information Center

    John Deere Co., Moline, IL.

    This manual on modern gas and arc welding is one of a series of power mechanics texts and visual aids on the servicing of automotive and off-the-road agricultural and construction equipment. Materials provide basic information with illustrations for use by vocational students and teachers as well as shop servicemen and laymen. The eight sections…

  16. Clarifying evacuation options through fire behavior and traffic modeling

    Treesearch

    Carol L. Rice; Ronny J. Coleman; Mike Price

    2011-01-01

    Communities are becoming increasingly concerned with the variety of choices related to wildfire evacuation. We used ArcView with Network Analyst to evaluate the different options for evacuations during wildfire in a case study community. We tested overlaying fire growth patterns with the road network and population characteristics to determine recommendations for...

  17. Changing Your Life: Reflections on the Road Less Traveled

    ERIC Educational Resources Information Center

    Lancaster, James

    2005-01-01

    The career arc for many in student affairs involves an uncertain journey. Finding balance between the professional and personal life can be challenging. For some, changing careers in mid-stream, an emerging trend in some facets of the American working landscape, offers possibilities. For others, retiring after a full career and working part-time…

  18. Capacitated arc routing problem and its extensions in waste collection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fadzli, Mohammad; Najwa, Nurul; Luis, Martino

    2015-05-15

    Capacitated arc routing problem (CARP) is the youngest generation of graph theory that focuses on solving the edge/arc routing for optimality. Since many years, operational research devoted to CARP counterpart, known as vehicle routing problem (VRP), which does not fit to several real cases such like waste collection problem and road maintenance. In this paper, we highlighted several extensions of capacitated arc routing problem (CARP) that represents the real-life problem of vehicle operation in waste collection. By purpose, CARP is designed to find a set of routes for vehicles that satisfies all pre-setting constraints in such that all vehicles mustmore » start and end at a depot, service a set of demands on edges (or arcs) exactly once without exceeding the capacity, thus the total fleet cost is minimized. We also addressed the differentiation between CARP and VRP in waste collection. Several issues have been discussed including stochastic demands and time window problems in order to show the complexity and importance of CARP in the related industry. A mathematical model of CARP and its new version is presented by considering several factors such like delivery cost, lateness penalty and delivery time.« less

  19. High resolution angular sensor. [reducing ring laser gyro output quantization using phase locked loops

    NASA Technical Reports Server (NTRS)

    Gneses, M. I.; Berg, D. S.

    1981-01-01

    Specifications for the pointing stabilization system of the large space telescope were used in an investigation of the feasibility of reducing ring laser gyro output quantization to the sub-arc-second level by the use of phase locked loops and associated electronics. Systems analysis procedures are discussed and a multioscillator laser gyro model is presented along with data on the oscillator noise. It is shown that a second order closed loop can meet the measurement noise requirements when the loop gain and time constant of the loop filter are appropriately chosen. The preliminary electrical design is discussed from the standpoint of circuit tradeoff considerations. Analog, digital, and hybrid designs are given and their applicability to the high resolution sensor is examined. the electrical design choice of a system configuration is detailed. The design and operation of the various modules is considered and system block diagrams are included. Phase 1 and 2 test results using the multioscillator laser gyro are included.

  20. 15 CFR 265.21 - Improper use of roads as thoroughfares.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Improper use of roads as thoroughfares... § 265.21 Improper use of roads as thoroughfares. Except as otherwise provided herein, no person shall drive a motor vehicle or bicycle onto the site for the sole purpose of using the roads of the site as a...

  1. The Serum Response Factor and a Putative Novel Transcription Factor Regulate Expression of the Immediate-Early Gene Arc/Arg3.1 in Cultured Cortical Neurons

    PubMed Central

    Pintchovski, Sean A.; Peebles, Carol L.; Kim, Hong Joo; Verdin, Eric; Finkbeiner, Steven

    2010-01-01

    The immediate-early effector gene Arc/Arg3.1 is robustly upregulated by synaptic activity associated with learning and memory. Here we show in primary cortical neuron culture that diverse stimuli induce Arc expression through new transcription. Searching for regulatory regions important for Arc transcription, we found nine DNaseI-sensitive nucleosome-depleted sites at this genomic locus. A reporter gene encompassing these sites responded to synaptic activity in an NMDA receptor–dependent manner, consistent with endogenous Arc mRNA. Responsiveness mapped to two enhancer regions ∼6.5 kb and ∼1.4 kb upstream of Arc. We dissected these regions further and found that the proximal enhancer contains a functional and conserved “Zeste-like” response element that binds a putative novel nuclear protein in neurons. Therefore, activity regulates Arc transcription partly by a novel signaling pathway. We also found that the distal enhancer has a functional and highly conserved serum response element. This element binds serum response factor, which is recruited by synaptic activity to regulate Arc. Thus, Arc is the first target of serum response factor that functions at synapses to mediate plasticity. PMID:19193899

  2. Numerical investigation of the double-arcing phenomenon in a cutting arc torch

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mancinelli, B. R., E-mail: bmancinelli@frvt.utn.edu.ar; Minotti, F. O.; Kelly, H.

    2014-07-14

    A numerical investigation of the double-arcing phenomenon in a cutting arc torch is reported. The dynamics of the double-arcing were simulated by using a two-dimensional model of the gas breakdown development in the space-charge layer contiguous to the nozzle of a cutting arc torch operated with oxygen. The kinetic scheme includes ionization of heavy particles by electron impact, electron attachment, electron detachment, electron–ion recombination, and ion–ion recombination. Complementary measurements during double-arcing phenomena were also conducted. A marked rise of the nozzle voltage was found. The numerical results showed that the dynamics of a cathode spot at the exit of themore » nozzle inner surface play a key role in the raising of the nozzle voltage, which in turn allows more electrons to return to the wall at the nozzle inlet. The return flow of electrons thus closes the current loop of the double-arcing. The increase in the (floating) nozzle voltage is due to the fact that the increased electron emission at the spot is mainly compensated by the displacement current (the ions do not play a relevant role due to its low-mobility) until that the stationary state is achieved and the electron return flow fully-compensates the electron emission at the spot. A fairly good agreement was found between the model and the experiment for a spot emission current growth rate of the order of 7 × 10{sup 4} A/s.« less

  3. The Dynamics of the Stapedial Acoustic Reflex.

    NASA Astrophysics Data System (ADS)

    Moss, Sherrin Mary

    Available from UMI in association with The British Library. This thesis aims to separate the neural and muscular components of the stapedial acoustic reflex, both anatomically and physiologically. It aims to present an hypothesis to account for the differences between ipsilateral and contralateral reflex characteristics which have so far been unexplained, and achieve a greater understanding of the mechanisms underlying the reflex dynamics. A technique enabling faithful reproduction of the time course of the reflex is used throughout the experimental work. The technique measures tympanic membrane displacement as a result of reflex stapedius muscle contraction. The recorded response can be directly related to the mechanics of the middle ear and stapedius muscle contraction. Some development of the technique is undertaken by the author. A model of the reflex neural arc and stapedius muscle dynamics is evolved that is based upon a second order system. The model is unique in that it includes a latency in the ipsilateral negative feedback loop. Oscillations commonly observed on reflex responses are seen to be produced because of the inclusion of a latency in the feedback loop. The model demonstrates and explains the complex relationships between neural and muscle dynamic parameters observed in the experimental work. This more comprehensive understanding of the interaction between the stapedius dynamics and the neural arc of the reflex would not usually have been possible using human subjects, coupled with a non-invasive measurement technique. Evidence from the experimental work revealed the ipsilateral reflex to have, on average, a 5 dB lower threshold than the contralateral reflex. The oscillatory charcteristics, and the steady state response, of the contralateral reflex are also seen to be significantly different from those of the ipsilateral reflex. An hypothesis to account for the experimental observations is proposed. It is propounded that chemical neurotransmitters, and their effect upon the contralateral reflex arc from the site of the superior olivary complex to the motoneurones innervating the stapedius, account for the difference between the contralateral and ipsilateral reflex thresholds and dynamic characteristics. In the past two years the measurement technique used for the experimental work has developed from an audiological to a neurological diagnostic tool. This has enabled the results from the study to be applied in the field for valuable biomechanical and neurological explanations of the reflex response. (Abstract shortened by UMI.).

  4. [Two cases of afferent loop syndrome caused by obstruction at the jejuno-jejunostomy site in the Roux-en-Y loop that were successfully treated by endoscopic balloon dilatation].

    PubMed

    Yasuda, Atsushi; Imamoto, Haruhiko; Furukawa, Hiroshi; Imano, Motohiro; Yasuda, Takushi; Okuno, Kiyokata

    2014-11-01

    We report 2 rare cases of afferent loop syndrome caused by obstruction at the jejuno-jejunostomy site in the Roux-en-Y loop after total gastrectomy, which was successfully treated by endoscopic balloon dilatation of the anastomotic stenosis. Case 1: A 62-year-old woman presented with malaise and lower abdominal distension 6 months after laparoscopy-assisted total gastrectomy with Roux-en-Y reconstruction. She was diagnosed with afferent loop syndrome; CT imaging indicated marked dilatation of the afferent loop, with membranous obstruction at the jejuno-jejunostomy site in the Roux-en-Y loop. Although almost complete occlusion was noted at the jejuno-jejunostomy site, the obstruction was successfully relieved by endoscopic balloon dilation using TandemTM XL Triple Lumen ERCP Cannula (Boston Scientific)®. Case 2: A 70-year-old man presented with malaise and lower abdominal distension 3 years after laparoscopy-assisted total gastrectomy with Roux-en-Y reconstruction. He was diagnosed with afferent loop syndrome; CT imaging indicated complete obstruction at the jejuno-jejunostomy site in the Roux-en-Y loop. As in case 1, the obstruction was successfully treated by endoscopic balloon dilatation of the occluded anastomosis.

  5. Nonlinear identification of the total baroreflex arc: higher-order nonlinearity

    PubMed Central

    Moslehpour, Mohsen; Kawada, Toru; Sunagawa, Kenji; Sugimachi, Masaru

    2016-01-01

    The total baroreflex arc is the open-loop system relating carotid sinus pressure (CSP) to arterial pressure (AP). The nonlinear dynamics of this system were recently characterized. First, Gaussian white noise CSP stimulation was employed in open-loop conditions in normotensive and hypertensive rats with sectioned vagal and aortic depressor nerves. Nonparametric system identification was then applied to measured CSP and AP to establish a second-order nonlinear Uryson model. The aim in this study was to assess the importance of higher-order nonlinear dynamics via development and evaluation of a third-order nonlinear model of the total arc using the same experimental data. Third-order Volterra and Uryson models were developed by employing nonparametric and parametric identification methods. The R2 values between the AP predicted by the best third-order Volterra model and measured AP in response to Gaussian white noise CSP not utilized in developing the model were 0.69 ± 0.03 and 0.70 ± 0.03 for normotensive and hypertensive rats, respectively. The analogous R2 values for the best third-order Uryson model were 0.71 ± 0.03 and 0.73 ± 0.03. These R2 values were not statistically different from the corresponding values for the previously established second-order Uryson model, which were both 0.71 ± 0.03 (P > 0.1). Furthermore, none of the third-order models predicted well-known nonlinear behaviors including thresholding and saturation better than the second-order Uryson model. Additional experiments suggested that the unexplained AP variance was partly due to higher brain center activity. In conclusion, the second-order Uryson model sufficed to represent the sympathetically mediated total arc under the employed experimental conditions. PMID:27629885

  6. Manual wheelchair propulsion patterns on natural surfaces during start-up propulsion.

    PubMed

    Koontz, Alicia M; Roche, Bailey M; Collinger, Jennifer L; Cooper, Rory A; Boninger, Michael L

    2009-11-01

    To classify propulsion patterns over surfaces encountered in the natural environment during start-up and compare selected biomechanical variables between pattern types. Case series. National Veterans Wheelchair Games, Minneapolis, MN, 2005. Manual wheelchair users (N=29). Subjects pushed their wheelchairs from a resting position over high-pile carpet, over linoleum, and up a ramp with a 5 degrees incline while propulsion kinematics and kinetics were recorded with a motion capture system and an instrumented wheel. Three raters classified the first 3 strokes as 1 of 4 types on each surface: arc, semicircular (SC), single looping over propulsion (SL), and double looping over propulsion (DL). The Fisher exact test was used to assess pattern changes between strokes and surface type. A multiple analysis of variance test was used to compare peak and average resultant force and moment about the hub, average wheel velocity, stroke frequency, contact angle, and distance traveled between stroke patterns. SL was the most common pattern used during start-up propulsion (44.9%), followed by arc (35.9%), DL (14.1%), and SC (5.1%). Subjects who dropped their hands below the rim during recovery achieved faster velocities and covered greater distances (.016< or =P< or =.075) during start-up on linoleum and carpet and applied more force during start-up on the ramp compared with those who used an arc pattern (P=.066). Classifying propulsion patterns is a difficult task that should use multiple raters. In addition, propulsion patterns change during start-up, with an arc pattern most prevalent initially. The biomechanical findings in this study agree with current clinical guidelines that recommend training users to drop the hand below the pushrim during recovery.

  7. Possible large-volume mafic explosive eruptions in the Izu arc recorded in IODP Site U1436

    NASA Astrophysics Data System (ADS)

    Tamura, Y.; Jutzeler, M.; Schindlbeck, J. C.; Nichols, A. R.; DeBari, S.; Gill, J.; Busby, C. J.; Blum, P.

    2014-12-01

    The Izu-Bonin-Mariana volcanic arc system is an excellent example of an intraoceanic convergent margin where the effects of crustal anatexis and assimilation are considered to be minimal. The Izu fore arc is a repository of ashes erupted in the Izu-Bonin frontal arc because the prevailing wind blows from west to east. IODP Site U1436 (proposed Site IBM-4GT), located at 32°23.88'N, 140°21.93'E, lies in the western part of the Izu fore arc basin, ~60 km east of the arc-front volcano Aogashima, ~170 km west of the axis of the Izu-Bonin Trench, 1.5 km west of ODP Site 792, and at 1776 mbsl. It was drilled in April-May 2014, during IODP Expedition 350, as a 150 m deep geotechnical test hole for potential future deep drilling at proposed Site IBM-4 using the D/V Chikyu. The stratigraphic record of Late Pleistocene mafic and silicic explosive volcanic products from the arc front consists of tuffaceous mud interstratified with mafic and evolved ash and lapilli, including distinctive black glassy mafic ash layers. These distinctive intervals are basaltic andesite and the most mafic deposits analyzed shipboard at Site U1436. The facies appeared to be unusually homogeneous in componentry and texture; the overwhelmingly glassy nature of the ash suggests subaqueous explosive eruption, and its good sorting suggests deposition by vertical settling through the water column from an ash plume that reached the atmosphere. An alterative hypothesis is that the ash layers have been redeposited in bathymetric lows by submarine density currents. These black glassy mafic ash layers attracted a great deal of interest among the science party because, if the first hypothesis is correct, they could record large-volume mafic explosive eruptions. As a result three more holes were drilled at Site U1436, in order to recover undisturbed examples of these layers. Samples from each hole are currently undergoing post-cruise geochemical (major, traces and volatiles) and componentry analysis to test these two hypotheses in more detail.

  8. 3D Quantum Hall Effect of Fermi Arc in Topological Semimetals

    NASA Astrophysics Data System (ADS)

    Wang, C. M.; Sun, Hai-Peng; Lu, Hai-Zhou; Xie, X. C.

    2017-09-01

    The quantum Hall effect is usually observed in 2D systems. We show that the Fermi arcs can give rise to a distinctive 3D quantum Hall effect in topological semimetals. Because of the topological constraint, the Fermi arc at a single surface has an open Fermi surface, which cannot host the quantum Hall effect. Via a "wormhole" tunneling assisted by the Weyl nodes, the Fermi arcs at opposite surfaces can form a complete Fermi loop and support the quantum Hall effect. The edge states of the Fermi arcs show a unique 3D distribution, giving an example of (d -2 )-dimensional boundary states. This is distinctly different from the surface-state quantum Hall effect from a single surface of topological insulator. As the Fermi energy sweeps through the Weyl nodes, the sheet Hall conductivity evolves from the 1 /B dependence to quantized plateaus at the Weyl nodes. This behavior can be realized by tuning gate voltages in a slab of topological semimetal, such as the TaAs family, Cd3 As2 , or Na3Bi . This work will be instructive not only for searching transport signatures of the Fermi arcs but also for exploring novel electron gases in other topological phases of matter.

  9. Identifying the origins of local atmospheric deposition in the steel industry basin of Luxembourg using the chemical and isotopic composition of the lichen Xanthoria parietina.

    PubMed

    Hissler, Christophe; Stille, Peter; Krein, Andreas; Geagea, Majdi Lahd; Perrone, Thierry; Probst, Jean-Luc; Hoffmann, Lucien

    2008-11-01

    Trace metal atmospheric contamination was assessed in one of the oldest European industrial sites of steel production situated in the southern part of the Grand-Duchy of Luxembourg. Using elemental ratios as well as Pb, Sr, and Nd isotopic compositions as tracers, we found preliminary results concerning the trace metal enrichment and the chemical/isotopic signatures of the most important emission sources using the lichen Xanthoria parietina sampled at 15 sites along a SW-NE transect. The concentrations of these elements decreased with increasing distance from the historical and actual steel-work areas. The combination of the different tracers (major elements, Rare Earth Element ratios, Pb, Sr and Nd isotopes) enabled us to distinguish between three principal sources: the historical steel production (old tailings corresponding to blast-furnace residues), the present steel production (industrial sites with arc electric furnace units) and the regional background (baseline) components. Other anthropogenic sources including a waste incinerator and major roads had only weak impacts on lichen chemistry and isotopic ratios. The correlation between the Sr and Nd isotope ratios indicated that the Sr-Nd isotope systems represented useful tools to trace atmospheric emissions of factories using scrap metal for steel production.

  10. Covalent attachment of Arc repressor subunits by a peptide linker enhances affinity for operator DNA.

    PubMed

    Robinson, C R; Sauer, R T

    1996-01-09

    By designing a recombinant gene containing tandem copies of the arc coding sequence with intervening DNA encoding the linker sequence GGGSGGGTGGGSGGG, the two subunits of the P22 Are repressor dimer have been covalently linked to form a single-chain protein called Arc-L1-Arc. The 15-residue linker joins the C-terminus of one monomer to the N-terminus of the second, a distance of approximately 45 A in the Arc-operator cocrystal structure. Arc-L1-Arc is expressed at high levels in Escherichia coli, with no evidence of degradation or proteolytic clipping of the linker, and is more active than wild-type Arc in repression assays. The purified Arc-L1-Arc protein has the molecular weight expected for the designed protein and unfolds cooperatively, reversibly, and with no concentration dependence in thermal-denaturation studies. Arc-L1-Arc protects operator DNA in a manner indistinguishable from that of wild-type Arc in DNase I and copper-phenanthroline footprinting studies, but the covalent attachment of the two monomers results in enhanced affinity for operator DNA. Arc-L1-Arc binds operator DNA half-maximally at a concentration of 1.7 pM, compared with the wild-type value of 185 pM, and also binds DNA fragments containing the left or right operator half-sites more tightly than wild type. Because wild-type Arc is monomeric at sub-nanomolar concentrations and must dimerize before binding to the operator, it was anticipated that Arc-L1-Arc would exhibit a lower half-maximal binding concentration. However, even when the change from a monomeric to a dimeric species is taken into account, the affinity of Arc-L1-Arc for operator and half-operator DNA is greater than the wild-type affinity. This tighter binding appears to result from slower dissociation, as Arc-L1-Arc DNA complexes with full or half-site operators dissociate at rates 5-10 times slower than the corresponding Arc--DNA complexes. Hence, the activity of the designed Arc-L1-Arc protein is substantially increased relative to wild-type Arc in a variety of assays.

  11. Regional-scale input of dispersed and discrete volcanic ash to the Izu-Bonin and Mariana subduction zones

    NASA Astrophysics Data System (ADS)

    Scudder, Rachel P.; Murray, Richard W.; Schindlbeck, Julie C.; Kutterolf, Steffen; Hauff, Folkmar; McKinley, Claire C.

    2014-11-01

    We have geochemically and statistically characterized bulk marine sediment and ash layers at Ocean Drilling Program Site 1149 (Izu-Bonin Arc) and Deep Sea Drilling Project Site 52 (Mariana Arc), and have quantified that multiple dispersed ash sources collectively comprise ˜30-35% of the hemipelagic sediment mass entering the Izu-Bonin-Mariana subduction system. Multivariate statistical analyses indicate that the bulk sediment at Site 1149 is a mixture of Chinese Loess, a second compositionally distinct eolian source, a dispersed mafic ash, and a dispersed felsic ash. We interpret the source of these ashes as, respectively, being basalt from the Izu-Bonin Front Arc (IBFA) and rhyolite from the Honshu Arc. Sr-, Nd-, and Pb isotopic analyses of the bulk sediment are consistent with the chemical/statistical-based interpretations. Comparison of the mass accumulation rate of the dispersed ash component to discrete ash layer parameters (thickness, sedimentation rate, and number of layers) suggests that eruption frequency, rather than eruption size, drives the dispersed ash record. At Site 52, the geochemistry and statistical modeling indicates that Chinese Loess, IBFA, dispersed BNN (boninite from Izu-Bonin), and a dispersed felsic ash of unknown origin are the sources. At Site 1149, the ash layers and the dispersed ash are compositionally coupled, whereas at Site 52 they are decoupled in that there are no boninite layers, yet boninite is dispersed within the sediment. Changes in the volcanic and eolian inputs through time indicate strong arc-related and climate-related controls.

  12. An ArcGIS decision support tool for artificial reefs site selection (ArcGIS ARSS)

    NASA Astrophysics Data System (ADS)

    Stylianou, Stavros; Zodiatis, George

    2017-04-01

    Although the use and benefits of artificial reefs, both socio-economic and environmental, have been recognized with research and national development programmes worldwide their development is rarely subjected to a rigorous site selection process and the majority of the projects use the traditional (non-GIS) approach, based on trial and error mode. Recent studies have shown that the use of Geographic Information Systems, unlike to traditional methods, for the identification of suitable areas for artificial reefs siting seems to offer a number of distinct advantages minimizing possible errors, time and cost. A decision support tool (DSS) has been developed based on the existing knowledge, the multi-criteria decision analysis techniques and the GIS approach used in previous studies in order to help the stakeholders to identify the optimal locations for artificial reefs deployment on the basis of the physical, biological, oceanographic and socio-economic features of the sites. The tool provides to the users the ability to produce a final report with the results and suitability maps. The ArcGIS ARSS support tool runs within the existing ArcMap 10.2.x environment and for the development the VB .NET high level programming language has been used along with ArcObjects 10.2.x. Two local-scale case studies were conducted in order to test the application of the tool focusing on artificial reef siting. The results obtained from the case studies have shown that the tool can be successfully integrated within the site selection process in order to select objectively the optimal site for artificial reefs deployment.

  13. Network Level Carbon Dioxide Emissions From On-road Sources in the Portland OR, (USA) Metropolitan Area

    NASA Astrophysics Data System (ADS)

    Powell, J.; Butenhoff, C. L.; Rice, A. L.

    2014-12-01

    To mitigate climate change, governments at multiple levels are developing policies to decrease anthropogenic carbon dioxide (CO2) emissions. The City of Portland (Oregon) and Multnomah County have adopted a Climate Action Plan with a stated goal of reducing emissions to 80% below 1990 levels by 2050. The transportation sector alone accounts for about 40% of total emissions in the Portland metropolitan area. Here we show a new street-level model of on-road mobile CO2 emissions for the Portland, OR metropolitan region. The model uses hourly traffic counter recordings made by the Portland Bureau of Transportation at 9,352 sites over 21 years (1986-2006), augmented with freeway loop detector data from the Portland Regional Transportation Archive Listing (PORTAL) transportation data archive. We constructed a land use regression model to fill in traffic network gaps with traffic counts as the dependent variable using GIS data such as road class (32 categories) and population density. The Environmental Protection Agency (EPA) MOtor Vehicle Emission Simulator (MOVES) model was used to estimate transportation CO2 emissions. The street-level emissions can be aggregated and gridded and used as input to atmospheric transport models for comparison with atmospheric measurements. This model also provides an independent assessment of top-down inventories that determine emissions from fuel sales, while being an important component of our ongoing effort to assess the effectiveness of emission mitigation strategies at the urban scale.

  14. 75 FR 49912 - Foreign-Trade Zone 40-Cleveland, OH; Site Renumbering Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ...)--Cleveland Business Park, Cleveland; Site 3 (450 acres)--Burke Lakefront Airport, 1501 North Marginal Road..., Glenwillow; Site 5 (17 acres)--within the Collinwood Industrial Park, South Waterloo (South Marginal) Road...

  15. Geologic field-trip guide to the Lassen segment of the Cascades Arc, northern California

    USGS Publications Warehouse

    Clynne, Michael A.; Muffler, L. J. Patrick

    2017-08-17

    This field-trip guide provides an overview of Quaternary volcanism in and around Lassen Volcanic National Park, California, emphasizing the stratigraphy of the Lassen Volcanic Center. The guide is designed to be self-guided and to focus on geologic features and stratigraphy that can be seen easily from the road network.

  16. Using GIS technology to analyze and understand wet meadow ecosystems

    Treesearch

    Joy Rosen; Roy Jemison; David Pawelek; Daniel Neary

    1999-01-01

    A Cibola National Forest wet meadow restoration was implemented as part of the Forest Road 49 enhancement near Grants, New Mexico. An Arc/View 3.0 Geographic Information System (GIS) was used to track the recovery of this ecosystem. Layers on topography, hydrology, vegetation, soils and human alterations were compiled using a GPS and commonly available data....

  17. Integrating traffic operation with emission impact using dual-loop data.

    DOT National Transportation Integrated Search

    2012-02-22

    "Transportation contributes great amount of green house gases and other pollutant emissions to the global environment. Localized analysis of on-road traffic source emissions is often required by the U.S. Environmental Protection Agency (EPA) for proj...

  18. ARC: A compact, high-field, disassemblable fusion nuclear science facility and demonstration power plant

    NASA Astrophysics Data System (ADS)

    Sorbom, Brandon; Ball, Justin; Palmer, Timothy; Mangiarotti, Franco; Sierchio, Jennifer; Bonoli, Paul; Kasten, Cale; Sutherland, Derek; Barnard, Harold; Haakonsen, Christian; Goh, Jon; Sung, Choongki; Whyte, Dennis

    2014-10-01

    The Affordable, Robust, Compact (ARC) reactor conceptual design aims to reduce the size, cost, and complexity of a combined Fusion Nuclear Science Facility (FNSF) and demonstration fusion pilot power plant. ARC is a 270 MWe tokamak reactor with a major radius of 3.3 m, a minor radius of 1.1 m, and an on-axis magnetic field of 9.2 T. ARC has Rare Earth Barium Copper Oxide (REBCO) superconducting toroidal field coils with joints to allow disassembly, allowing for removal and replacement of the vacuum vessel as a single component. Inboard-launched current drive of 25 MW LHRF power and 13.6 MW ICRF power is used to provide a robust, steady state core plasma far from disruptive limits. ARC uses an all-liquid blanket, consisting of low pressure, slowly flowing Fluorine Lithium Beryllium (FLiBe) molten salt. The liquid blanket acts as a working fluid, coolant, and tritium breeder, and minimizes the solid material that can become activated. The large temperature range over which FLiBe is liquid permits blanket operation at 800-900 K with single phase fluid cooling and allows use of a high-efficiency Brayton cycle for electricity production in the secondary coolant loop.

  19. Stepwise Loop Insertion Strategy for Active Site Remodeling to Generate Novel Enzyme Functions.

    PubMed

    Hoque, Md Anarul; Zhang, Yong; Chen, Liuqing; Yang, Guangyu; Khatun, Mst Afroza; Chen, Haifeng; Hao, Liu; Feng, Yan

    2017-05-19

    The remodeling of active sites to generate novel biocatalysts is an attractive and challenging task. We developed a stepwise loop insertion strategy (StLois), in which randomized residue pairs are inserted into active site loops. The phosphotriesterase-like lactonase from Geobacillus kaustophilus (GkaP-PLL) was used to investigate StLois's potential for changing enzyme function. By inserting six residues into active site loop 7, the best variant ML7-B6 demonstrated a 16-fold further increase in catalytic efficiency toward ethyl-paraoxon compared with its initial template, that is a 609-fold higher, >10 7 fold substrate specificity shift relative to that of wild-type lactonase. The remodeled variants displayed 760-fold greater organophosphate hydrolysis activity toward the organophosphates parathion, diazinon, and chlorpyrifos. Structure and docking computations support the source of notably inverted enzyme specificity. Considering the fundamental importance of active site loops, the strategy has potential for the rapid generation of novel enzyme functions by loop remodeling.

  20. [Influence of road on breeding habitat of Nipponia nippon based on MaxEnt model].

    PubMed

    Zhang, Hui; Gao, Ji Xi; Ma, Meng Xiao; Shao, Fang Ze; Wang, Qiao; Li, Guang Yu; Qiu, Jie; Zhou, Ke Xin

    2017-04-18

    Quantitative study on effects of roads on suitable breeding habitats of wildlife is one of topics that need in-depth research in road ecology. Crested ibis (Nipponia nippon), a first class nationally protected bird species, is the species of interest in this research. Using the Maximum Entropy Models (MaxEnt) in the Species Distribution Model (SDM) toolbox of ArcGIS, autocorrelation of environmental variables were analyzed and environmental variables with r>0.8 were removed. Ten environmental variables were chosen as impact factors for the breeding habitat of crested ibis, including mean temperature of coldest quarter, landscape type, normalized difference vegetation index(NDVI), slope, aspect, distance to waters, distance to paddy field, distance to high-grade roads (expressway, national way, provincial way), and distance to low-grade roads (country road). By analyzing the contribution rate of each environmental variable, the results showed that the mean temperature of coldest quarter, landscape type, distance to paddy field, and distance to high-grade roads were the main factors determining breeding habitat of crested ibis. The suitable distribution of crested ibis' nesting area was under the following scenarios: variable road present (scenario1), high-grade road absent (scenario2), and low-grade road absent (scenario 3). The results showed that the presence of roads affected suitable nesting areas of crested ibis with high-grade roads showing a larger influence than low-grade roads. The presence of high-grade roads and low-grade roads decreased the suitable nesting areas of crested ibis by 66.23 and 35.69 km 2 , respectively. The crested ibis preferred to nest in areas distant from high-grade roads, with an average road avoidance distance of 1500 m. This study was of great significance for formulating management measures to protect crested ibis and provide a reference for quantitative assessment on impacts of engineering and construction projects on wildlife.

  1. Darwin : The Third DOE ARM TWP ARCS Site /

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Clements, William E.; Jones, L. A.; Baldwin, T.

    2002-01-01

    The United States Department of Energy's (DOE) Atmospheric Radiation Measurement (ARM) Program began operations in its Tropical Western Pacific (TWP) locale in October 1996 when the first Atmospheric Radiation and Cloud Station (ARCS) began collecting data on Manus Island in Papua New Guinea (PNG). Two years later, in November 1998, a second ARCS began operations on the island of Nauru in the Central Pacific. Now a third ARCS has begun collecting data in Darwin, Australia. The Manus, Nauru, and Darwin sites are operated through collaborative agreements with the PNG National Weather Service, The Nauru Department of Industry and Economic Developmentmore » (IED), and the Australian Bureau of Meteorology's (BOM) Special Services Unit (SSU) respectively. All ARM TWP activities in the region are coordinated with the South Pacific Regional Environment Programme (SPREP) based in Apia, Samoa. The Darwin ARM site and its role in the ARM TWP Program are discussed.« less

  2. Roads and Airfields I (Programed Instruction). Engineer Subcourse 64-9.

    ERIC Educational Resources Information Center

    Army Engineer School, Fort Belvoir, VA.

    The document is a programed text for a correspondence course in the planning, construction, and maintenance of military roads and airfields. There are seven lessons: construction requirements and design criteria; road reconnaissance and site selection; airfield reconnaissance and site selection; layout procedures, construction staking, and field…

  3. 11. View from heat sink, south oblique of missile site ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. View from heat sink, south oblique of missile site control building - Stanley R. Mickelsen Safeguard Complex, Missile Site Control Building, Northeast of Tactical Road; southeast of Tactical Road South, Nekoma, Cavalier County, ND

  4. 75 FR 51757 - Foreign-Trade Zone 167-Green Bay, WI; Site Renumbering Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... South Point Road and Airport Road adjacent to Austin Straubel Airport in Ashwaubenon, Brown County; Site..., Winnebago County; Site 3 (1,654 acres)--Austin Straubel Airport located in Ashwaubenon and Hobart, Brown...

  5. DNA looping by FokI: the impact of twisting and bending rigidity on protein-induced looping dynamics

    PubMed Central

    Laurens, Niels; Rusling, David A.; Pernstich, Christian; Brouwer, Ineke; Halford, Stephen E.; Wuite, Gijs J. L.

    2012-01-01

    Protein-induced DNA looping is crucial for many genetic processes such as transcription, gene regulation and DNA replication. Here, we use tethered-particle motion to examine the impact of DNA bending and twisting rigidity on loop capture and release, using the restriction endonuclease FokI as a test system. To cleave DNA efficiently, FokI bridges two copies of an asymmetric sequence, invariably aligning the sites in parallel. On account of the fixed alignment, the topology of the DNA loop is set by the orientation of the sites along the DNA. We show that both the separation of the FokI sites and their orientation, altering, respectively, the twisting and the bending of the DNA needed to juxtapose the sites, have profound effects on the dynamics of the looping interaction. Surprisingly, the presence of a nick within the loop does not affect the observed rigidity of the DNA. In contrast, the introduction of a 4-nt gap fully relaxes all of the torque present in the system but does not necessarily enhance loop stability. FokI therefore employs torque to stabilise its DNA-looping interaction by acting as a ‘torsional’ catch bond. PMID:22373924

  6. An integrated optical sensor for GMAW feedback control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Taylor, P.L.; Watkins, A.D.; Larsen, E.D.

    1992-08-01

    The integrated optical sensor (IOS) is a multifunction feedback control sensor for arc welding, that is computer automated and independent of significant operator interaction. It is based on three major ``off-the-shelf`` components: a charged coupled device (CCD) camera, a diode laser, and a processing computer. The sensor head is compact and lightweight to avoid interference with weld head mobility, hardened to survive the harsh operating environment, and free of specialized cooling and power requirements. The sensor is positioned behind the GMAW torch and measures weld pool position and width, standoff distance, and postweld centerline cooling rate. Weld pool position andmore » width are used in a feedback loop, by the weld controller, to track the weld pool relative to the weld joint, thus allowing compensation for such phenomena as arc blow. Sensor stand off distance is used in a feedback loop to control the contact tip to base metal distance during the welding process. Cooling rate information is used to infer the final metallurgical state of the weld bead and heat affected zone, thereby providing a means of controlling post weld mechanical properties.« less

  7. An integrated optical sensor for GMAW feedback control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Taylor, P.L.; Watkins, A.D.; Larsen, E.D.

    1992-01-01

    The integrated optical sensor (IOS) is a multifunction feedback control sensor for arc welding, that is computer automated and independent of significant operator interaction. It is based on three major off-the-shelf'' components: a charged coupled device (CCD) camera, a diode laser, and a processing computer. The sensor head is compact and lightweight to avoid interference with weld head mobility, hardened to survive the harsh operating environment, and free of specialized cooling and power requirements. The sensor is positioned behind the GMAW torch and measures weld pool position and width, standoff distance, and postweld centerline cooling rate. Weld pool position andmore » width are used in a feedback loop, by the weld controller, to track the weld pool relative to the weld joint, thus allowing compensation for such phenomena as arc blow. Sensor stand off distance is used in a feedback loop to control the contact tip to base metal distance during the welding process. Cooling rate information is used to infer the final metallurgical state of the weld bead and heat affected zone, thereby providing a means of controlling post weld mechanical properties.« less

  8. An interpretation of the polarization of microwave bursts. [solar emission

    NASA Technical Reports Server (NTRS)

    Kundu, M. R.; Vlahos, L.

    1979-01-01

    High-spatial-resolution (a few seconds of arc) observations of microwave bursts have demonstrated that only the impulsive phase of the burst is polarized; one observes only one polarity in the burst source if it is weak (Alissandrakis and Kundu) and both polarities if it is intense (Enome et al.). These results are interpreted in terms of an asymmetrical bipolar field structure of the loop in which the energetic electrons responsible for the radiation are contained. The role of unequal field strengths at the feet of the loop on the number of electrons trapped and their pitch angle distribution are discussed in a specific model. Computations of the polarized intensity originating from each foot of the loop seem to be consistent with the observations at present available.

  9. The development of an SC1 removable si-anti-reflective-coating

    NASA Astrophysics Data System (ADS)

    Yamada, Shintaro; Ke, Iou-Sheng; Cutler, Charlotte; Cui, Li; LaBeaume, Paul; Greene, Daniel; Popere, Bhooshan; Sullivan, Chris; Leonard, JoAnne; Coley, Suzanne; Wong, Sabrina; Ongayi, Owendi; Cameron, Jim; Clark, Michael B.; Fitzgibbons, Thomas C.

    2018-03-01

    A trilayer stack of spin-on-carbon (SOC), silicon anti-reflective coating (SiARC) and photoresist (PR) is often used to enable high resolution implant layers for integrated circuit manufacturing. Damage to substrates from SiARC removal using dry etching or aqueous hydrogen fluoride has increased the demand for innovative SiARC materials for implant lithography process. Wet strippable SiARCs (WS-SiARCs) capable of stripping under mild conditions such as SC1 (ammonium hydroxide/hydrogen peroxide/water) while maintaining key performance metrics of standard SiARCs is highly desirable. Minimizing the formation of Si-O-Si linkages by introducing organic crosslink sites was effective to impart SC1 solubility particularly after O2 dry etching. Incorporation of acidic groups onto the crosslinking site further improved SC1 solubility. A new siloxane polymer architecture that has SC1 active functionality in the polymer backbone was developed to further enhance SC1 solubility. A new SiARC formulation based on the new siloxane polymer achieved equivalent lithographic performances to a classic SiARC and SC1 strip rate >240Å/min under a relatively low concentration SC1 condition such as ammonium hydroxide/hydrogen peroxide/water=1/1/40.

  10. Silicic melt evolution in the early Izu-Bonin arc recorded in detrital zircons: Zircon U-Pb geochronology and trace element geochemistry for Site U1438, Amami Sankaku Basin

    NASA Astrophysics Data System (ADS)

    Barth, A. P.; Tani, K.; Meffre, S.; Wooden, J. L.; Coble, M. A.

    2016-12-01

    Understanding the petrologic evolution of oceanic arc magmas through time is important because these arcs reveal the processes of formation and the early evolution of juvenile continental crust. The Izu-Bonin (IB) arc system has been targeted because it is one of several western Pacific intraoceanic arcs initiated at 50 Ma and because of its prominent spatial asymmetry, with widespread development of relatively enriched rear arc lavas. We examined Pb/U and trace element compositions in zircons recovered at IODP Site 351-U1438 and compared them to regional and global zircon suites. These new arc zircon data indicate that detrital zircons will yield new insights into the generation of IB silicic melts and form a set of useful geochemical proxies for interpreting ancient arc detrital zircon provenance. Project IBM drilling target IBM1 was explored by Expedition 351 at Site U1438, located in the proximal back-arc of the northern Kyushu-Palau Ridge (KPR) at 27.3°N. A 1.2 km thick section of Paleogene volcaniclastic rocks, increasingly lithified and hydrothermally altered with depth, constitutes a proximal rear arc sedimentary record of IB arc initiation and early arc evolution. The ages and compositions of U1438 zircons are compatible with provenance in one or more edifices of the northern KPR and are incompatible with drilling contamination. Melt zircon saturation temperatures and Ti-in-zircon thermometry suggest a provenance in relatively cool and silicic KPR melts. The abundances of selected trace elements with high native concentrations provide insight into the petrogenesis of U1438 detrital zircon host melts, and may be useful indicators of both short and long-term variations in melt compositions in arc settings. The U1438 zircons are slightly enriched in U and LREE and are depleted in Nb compared to zircons from mid-ocean ridges and the Parece-Vela Basin, as predicted for melts in a primitive oceanic arc setting with magmas derived from a highly depleted mantle source. Close age and geochemical affinity of U1438 detrital zircons to igneous zircons in Eocene leucotonalite from the partially exhumed intrusive suite at Komahashi-Daini Seamount in the northernmost KPR suggests that these zircons also can yield insight into the link between silicic volcanism and evolving tonalitic intrusions in the Paleogene IB arc.

  11. Extensive hydrothermal activity in the NE Lau basin revealed by ROV dives

    NASA Astrophysics Data System (ADS)

    Embley, R. W.; Resing, J. A.; Tebo, B.; Baker, E. T.; Butterfield, D. A.; Chadwick, B.; Davis, R.; de Ronde, C. E. J.; Lilley, M. D.; Lupton, J. E.; Merle, S. G.; Rubin, K. H.; Shank, T. M.; Walker, S. L.; Arculus, R. J.; Bobbitt, A. M.; Buck, N. J.; Caratori Tontini, F.; Crowhurst, P. V.; Mitchell, E.; Olson, E. J.; Ratmeyer, V.; Richards, S.; Roe, K. K.; Kenner-Chavis, P.; Martinez-Lyons, A.; Sheehan, C.; Brian, R.

    2014-12-01

    Dives with the QUEST 4000 ROV (Remotely Operated Vehicle) in September 2012 discovered nine hydrothermal sites in the arc and rear-arc region of the NE Lau Basin in 1150 m to 2630 m depth. These sites, originally detected by water column and seafloor surveys conducted in 2008-2011, include: (1) a paired sulfur-rich/black smoker field on the summit of a tectonically deformed magmatic arc volcano (Niua), (2) fracture-controlled black smoker venting on several small en echelon seamounts (north Matas) that lie between the magmatic arc and the backarc spreading center and (3) a magmatic degassing site on the summit of a dacite cone within a large (~12 km diameter) caldera volcano (Niuatahi). Dives at West Mata Seamount, which was undergoing strombolian volcanic activity and effusive rift-zone eruptions from 2008 to 2010, revealed a dormant volcanic phase in September 2012, with continued low-temperature diffuse venting. The high-temperature venting is likely driven by magmatic heat indicative of underlying partial melt zones and/or melt pockets distributed through the region. The occurrence of the youngest known boninite eruptions on the Mata volcanoes is consistent with subduction fluid flux melting extending into the rear-arc zone. Extension related to the transition from subduction to strike-slip motion of the northern Tonga Arc over the active Subduction-Transform Edge Propagator (STEP) fault probably contributes to the enhanced volcanism/hydrothermal activity in the NE Lau Basin. Chemosynthetic ecosystems at these sites range from mostly motile, lower diversity ecosystems at the eruptive/magmatically-degassing sites to higher diversity ecosystems with less mobile faunal components at the black-smoker systems. The wide range of fluid chemistry, water depth and geologic settings of the hydrothermal systems in this area provides an intriguing template to study the interaction of hydrothermal fluid chemistry, chemosynthetic habitats and their geologic underpinning within an arc/backarc setting.

  12. Hyperactive hydrothermal activity in the NE Lau basin revealed by ROV dives

    NASA Astrophysics Data System (ADS)

    Embley, R. W.; Resing, J. A.; Tebo, B.; Baker, E. T.; Butterfield, D. A.; Chadwick, B.; Davis, R.; de Ronde, C. E.; Lilley, M. D.; Lupton, J. E.; Merle, S. G.; Rubin, K. H.; Shank, T. M.; Walker, S. L.; Arculus, R. J.; Bobbitt, A. M.; Buck, N.; Caratori Tontini, F.; Crowhurst, P. V.; Mitchell, E.; Olson, E. J.; Ratmeyer, V.; Richards, S.; Roe, K. K.; Keener, P.; Martinez Lyons, A.; Sheehan, C.; Brian, R.

    2013-12-01

    Dives with the QUEST 4000 ROV (Remotely Operated Vehicle) in September 2012 discovered nine hydrothermal sites in the arc and rear-arc region of the NE Lau Basin in 1150 m to 2630 m depth. These sites, originally detected by water column and seafloor surveys conducted in 2008-2011, include: (1) a paired sulfur-rich/black smoker field on the summit of a tectonically deformed magmatic arc volcano (Niua), (2) fracture-controlled black smoker venting on several small en echelon seamounts (north Matas) that lie between the magmatic arc and the backarc spreading center and (3) a magmatic degassing site on the summit of a dacite cone within a large (~12 km diameter) caldera volcano (Niuatahi). Dives at West Mata Seamount, which was undergoing strombolian volcanic activity and effusive rift-zone eruptions from 2008 to 2010, revealed a dormant volcanic phase in September 2012, with continued low-temperature diffuse venting. The high-temperature venting is likely driven by magmatic heat indicative of underlying partial melt zones and/or melt pockets distributed through the region. The occurrence of the youngest known boninite eruptions on the Mata volcanoes is consistent with subduction fluid flux melting extending into the rear-arc zone. Extension related to the transition from subduction to strike-slip motion of the northern Tonga Arc over the active Subduction-Transform Edge Propagator (STEP) fault probably contributes to the enhanced volcanism/hydrothermal activity in the NE Lau Basin. Chemosynthetic ecosystems at these sites range from mostly motile, lower diversity ecosystems at the eruptive/magmatically-degassing sites to higher diversity ecosystems with less mobile faunal components at the black-smoker systems. The wide range of fluid chemistry, water depth and geologic settings of the hydrothermal systems in this area provides an intriguing template to study the interaction of hydrothermal fluid chemistry, chemosynthetic habitats and their geologic underpinning within an arc/backarc setting.

  13. Uncertainty of OpenStreetMap data for the road network in Cyprus

    NASA Astrophysics Data System (ADS)

    Demetriou, Demetris

    2016-08-01

    Volunteered geographic information (VGI) refers to the geographic data compiled and created by individuals which are rendered on the Internet through specific web-based tools for diverse areas of interest. One of the most well-known VGI projects is the OpenStreetMap (OSM) that provides worldwide free geospatial data representing a variety of features. A critical issue for all VGI initiatives is the quality of the information offered. Thus, this report looks into the uncertainty of the OSM dataset for the main road network in Cyprus. The evaluation is based on three basic quality standards, namely positional accuracy, completeness and attribute accuracy. The work has been carried out by employing the Model Builder of ArcGIS which facilitated the comparison between the OSM data and the authoritative data provided by the Public Works Department (PWD). Findings showed that the positional accuracy increases with the hierarchical level of a road, it varies per administrative District and around 70% of the roads have a positional accuracy within 6m compared to the reference dataset. Completeness in terms of road length difference is around 25% for three out of four road categories examined and road name completeness is 100% and around 40% for higher and lower level roads, respectively. Attribute accuracy focusing on road name is very high for all levels of roads. These outputs indicate that OSM data are good enough if they fit for the purpose of use. Furthermore, the study revealed some weaknesses of the methods used for calculating the positional accuracy, suggesting the need for methodological improvements.

  14. Lithium isotopic systematics of submarine vent fluids from arc and back-arc hydrothermal systems in the western Pacific

    NASA Astrophysics Data System (ADS)

    Araoka, Daisuke; Nishio, Yoshiro; Gamo, Toshitaka; Yamaoka, Kyoko; Kawahata, Hodaka

    2016-10-01

    The Li concentration and isotopic composition (δ7Li) in submarine vent fluids are important for oceanic Li budget and potentially useful for investigating hydrothermal systems deep under the seafloor because hydrothermal vent fluids are highly enriched in Li relative to seawater. Although Li isotopic geochemistry has been studied at mid-ocean-ridge (MOR) hydrothermal sites, in arc and back-arc settings Li isotopic composition has not been systematically investigated. Here we determined the δ7Li and 87Sr/86Sr values of 11 end-member fluids from 5 arc and back-arc hydrothermal systems in the western Pacific and examined Li behavior during high-temperature water-rock interactions in different geological settings. In sediment-starved hydrothermal systems (Manus Basin, Izu-Bonin Arc, Mariana Trough, and North Fiji Basin), the Li concentrations (0.23-1.30 mmol/kg) and δ7Li values (+4.3‰ to +7.2‰) of the end-member fluids are explained mainly by dissolution-precipitation model during high-temperature seawater-rock interactions at steady state. Low Li concentrations are attributable to temperature-related apportioning of Li in rock into the fluid phase and phase separation process. Small variation in Li among MOR sites is probably caused by low-temperature alteration process by diffusive hydrothermal fluids under the seafloor. In contrast, the highest Li concentrations (3.40-5.98 mmol/kg) and lowest δ7Li values (+1.6‰ to +2.4‰) of end-member fluids from the Okinawa Trough demonstrate that the Li is predominantly derived from marine sediments. The variation of Li in sediment-hosted sites can be explained by the differences in degree of hydrothermal fluid-sediment interactions associated with the thickness of the marine sediment overlying these hydrothermal sites.

  15. Coordination of the Arc Regulatory System and Pheromone-Mediated Positive Feedback in Controlling the Vibrio fischeri lux Operon

    PubMed Central

    Septer, Alecia N.; Stabb, Eric V.

    2012-01-01

    Bacterial pheromone signaling is often governed both by environmentally responsive regulators and by positive feedback. This regulatory combination has the potential to coordinate a group response among distinct subpopulations that perceive key environmental stimuli differently. We have explored the interplay between an environmentally responsive regulator and pheromone-mediated positive feedback in intercellular signaling by Vibrio fischeri ES114, a bioluminescent bacterium that colonizes the squid Euprymna scolopes. Bioluminescence in ES114 is controlled in part by N-(3-oxohexanoyl)-L-homoserine lactone (3OC6), a pheromone produced by LuxI that together with LuxR activates transcription of the luxICDABEG operon, initiating a positive feedback loop and inducing luminescence. The lux operon is also regulated by environmentally responsive regulators, including the redox-responsive ArcA/ArcB system, which directly represses lux in culture. Here we show that inactivating arcA leads to increased 3OC6 accumulation to initiate positive feedback. In the absence of positive feedback, arcA-mediated control of luminescence was only ∼2-fold, but luxI-dependent positive feedback contributed more than 100 fold to the net induction of luminescence in the arcA mutant. Consistent with this overriding importance of positive feedback, 3OC6 produced by the arcA mutant induced luminescence in nearby wild-type cells, overcoming their ArcA repression of lux. Similarly, we found that artificially inducing ArcA could effectively repress luminescence before, but not after, positive feedback was initiated. Finally, we show that 3OC6 produced by a subpopulation of symbiotic cells can induce luminescence in other cells co-colonizing the host. Our results suggest that even transient loss of ArcA-mediated regulation in a sub-population of cells can induce luminescence in a wider community. Moreover, they indicate that 3OC6 can communicate information about both cell density and the state of ArcA/ArcB. PMID:23152924

  16. The influence of repressor DNA binding site architecture on transcriptional control.

    PubMed

    Park, Dan M; Kiley, Patricia J

    2014-08-26

    How the architecture of DNA binding sites dictates the extent of repression of promoters is not well understood. Here, we addressed the importance of the number and information content of the three direct repeats (DRs) in the binding and repression of the icdA promoter by the phosphorylated form of the global Escherichia coli repressor ArcA (ArcA-P). We show that decreasing the information content of the two sites with the highest information (DR1 and DR2) eliminated ArcA binding to all three DRs and ArcA repression of icdA. Unexpectedly, we also found that DR3 occupancy functions principally in repression, since mutation of this low-information-content site both eliminated DNA binding to DR3 and significantly weakened icdA repression, despite the fact that binding to DR1 and DR2 was intact. In addition, increasing the information content of any one of the three DRs or addition of a fourth DR increased ArcA-dependent repression but perturbed signal-dependent regulation of repression. Thus, our data show that the information content and number of DR elements are critical architectural features for maintaining a balance between high-affinity binding and signal-dependent regulation of icdA promoter function in response to changes in ArcA-P levels. Optimization of such architectural features may be a common strategy to either dampen or enhance the sensitivity of DNA binding among the members of the large OmpR/PhoB family of regulators as well as other transcription factors. In Escherichia coli, the response regulator ArcA maintains homeostasis of redox carriers under O2-limiting conditions through a comprehensive repression of carbon oxidation pathways that require aerobic respiration to recycle redox carriers. Although a binding site architecture comprised of a variable number of sequence recognition elements has been identified within the promoter regions of ArcA-repressed operons, it is unclear how this variable architecture dictates transcriptional regulation. By dissecting the role of multiple sequence elements within the icdA promoter, we provide insight into the design principles that allow ArcA to repress transcription within diverse promoter contexts. Our data suggest that the arrangement of recognition elements is tailored to achieve sufficient repression of a given promoter while maintaining appropriate signal-dependent regulation of repression, providing insight into how diverse binding site architectures link changes in O2 with the fine-tuning of carbon oxidation pathway levels. Copyright © 2014 Park and Kiley.

  17. 76 FR 34692 - Inside Passage Electric Cooperative

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ... Electric Cooperative Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments..., the Inside Passage Electric Cooperative filed an application for a preliminary permit, pursuant to..., Operations Manager, Inside Passage Electric Cooperative, P.O. Box 210149, 12480 Mendenhall Loop Road, Auke...

  18. The Neutral Gas Desorption and Breakdown on a Metal-Dielectric Junction Immersed in a Plasma

    NASA Technical Reports Server (NTRS)

    Vayner, Boris; Galofaro, Joel; Ferguson, Dale; Lyons, Valerie J. (Technical Monitor)

    2002-01-01

    New results are presented of an experimental study and theoretical analysis of arcing on metal-dielectric junctions immersed in a low-density plasma. Two samples of conventional solar arrays have been used to investigate the effects of arcing within a wide range of neutral gas pressures, ion currents, and electron number densities. All data (except video) were obtained in digital form that allowed us to study the correlation between external parameters (plasma density, additional capacitance, bias voltage, etc) and arc characteristics (arc rate, arc current pulse width and amplitude, gas species partial pressures, intensities of spectral lines, and so on). Arc sites were determined by employing a video-camera, and it is shown that the most probable sites for arc inception are trip le-junctions, even though some arcs were initiated in gaps between cells. The effect of surface conditioning (decrease of arc rate due to outgassing) was clearly demonstrated. Moreover, a considerable increase in arc rate due to absorption of molecules from atmospheric air has been confirmed. The analysis of optical spectra (240-800 nm) reveals intense narrow atomic lines (Ag, H) and wide molecular bands (OH, CH, SiH, SiN) that confirm a complicated mechanism of arc plasma generation. The rate of plasma contamination due to arcing was measured by employing a mass-spectrometer. These measurements provided quite reliable data for the development of a theoretical model of plasma contamination, In conclusion, the arc threshold was increased to above 350 V (from 190 V) by keeping a sample in vacuum (20 micronTorr) for seven days. The results obtained are important for the understanding of the arc inception mechanism, which is absolutely essential for progress toward the design of high voltage solar arrays for space applications.

  19. Indirect effects of species interactions on habitat provisioning.

    PubMed

    Holbrook, Sally J; Schmitt, Russell J; Brooks, Andrew J

    2011-07-01

    Species that shelter in a biogenic habitat can influence their refugia and, in turn, play an essential role in shaping local patterns of biodiversity. Here we explore a positive feedback loop between the provisioning rate of habitat-forming branching corals and their associated fishes and show how interactions between two groups of fish--the planktivorous damselfish and predatory hawkfish--altered the feedback. A field experiment confirmed that skeletal growth of branching coral (genus Pocillopora) increased substantially with increasing numbers (biomass) of resident fishes, likely because they greatly increased the interstitial concentrations of nutrients. Because there is a positive relationship between colony size and number (biomass) of associated fishes (primarily damselfishes in the Family Pomacentridae), a structure-function feedback loop exists in which increasing numbers of damselfish enhance coral growth and larger corals host greater abundances (and species richness) of fish. However, interactions between damselfishes and arc-eye hawkfish, Paracirrhites arcatus, a largely solitary resident, can disrupt this positive feedback loop. Field surveys revealed a marked pattern of fish occupancy related to coral size: Pocillopora colonies of sufficient size to host fish (>40 cm circumference) had either groups of damselfish or an arc-eye hawkfish; only larger colonies (>75 cm) were occupied by both the damselfish and hawkfish. Subsequent short- and long-term experiments revealed that on intermediate-sized Pocillopora colonies, arc-eye hawkfish prevented the establishment of damselfish by suppressing their recruitment. The demographic consequences to the host coral were substantial; in a 1-year-long experiment, intermediate-size Pocillopora occupied by hawkfish grew at half the rate of corals that hosted groups of damselfish. These findings indicate that: (1) species which occupy a biogenic habitat can enhance the provisioning rate of their habitat; (2) such positive feedbacks between community structure and ecosystem function can be disrupted by a strong interactor; (3) even substantial consequences on ecosystem processes that arise can be difficult to discern.

  20. Generation of Silicic Melts in the Early Izu-Bonin Arc Recorded by Detrital Zircons in Proximal Arc Volcaniclastic Rocks From the Philippine Sea

    NASA Astrophysics Data System (ADS)

    Barth, A. P.; Tani, K.; Meffre, S.; Wooden, J. L.; Coble, M. A.; Arculus, R. J.; Ishizuka, O.; Shukle, J. T.

    2017-10-01

    A 1.2 km thick Paleogene volcaniclastic section at International Ocean Discovery Program Site 351-U1438 preserves the deep-marine, proximal record of Izu-Bonin oceanic arc initiation, and volcano evolution along the Kyushu-Palau Ridge (KPR). Pb/U ages and trace element compositions of zircons recovered from volcaniclastic sandstones preserve a remarkable temporal record of juvenile island arc evolution. Pb/U ages ranging from 43 to 27 Ma are compatible with provenance in one or more active arc edifices of the northern KPR. The abundances of selected trace elements with high concentrations provide insight into the genesis of U1438 detrital zircon host melts, and represent useful indicators of both short and long-term variations in melt compositions in arc settings. The Site U1438 zircons span the compositional range between zircons from mid-ocean ridge gabbros and zircons from relatively enriched continental arcs, as predicted for melts in a primitive oceanic arc setting derived from a highly depleted mantle source. Melt zircon saturation temperatures and Ti-in-zircon thermometry suggest a provenance in relatively cool and silicic melts that evolved toward more Th and U-rich compositions with time. Th, U, and light rare earth element enrichments beginning about 35 Ma are consistent with detrital zircons recording development of regional arc asymmetry and selective trace element-enriched rear arc silicic melts as the juvenile Izu-Bonin arc evolved.

  1. Arabidopsis ARC6 coordinates the division machineries of the inner and outer chloroplast membranes through interaction with PDV2 in the intermembrane space.

    PubMed

    Glynn, Jonathan M; Froehlich, John E; Osteryoung, Katherine W

    2008-09-01

    Chloroplasts arose from a free-living cyanobacterial endosymbiont and divide by binary fission. Division involves the assembly and constriction of the endosymbiont-derived, tubulin-like FtsZ ring on the stromal surface of the inner envelope membrane and the host-derived, dynamin-like ARC5 ring on the cytosolic surface of the outer envelope membrane. Despite the identification of many proteins required for plastid division, the factors coordinating the internal and external division machineries are unknown. Here, we provide evidence that this coordination is mediated in Arabidopsis thaliana by an interaction between ARC6, an FtsZ assembly factor spanning the inner envelope membrane, and PDV2, an ARC5 recruitment factor spanning the outer envelope membrane. ARC6 and PDV2 interact via their C-terminal domains in the intermembrane space, consistent with their in vivo topologies. ARC6 acts upstream of PDV2 to localize PDV2 (and hence ARC5) to the division site. We present a model whereby ARC6 relays information on stromal FtsZ ring positioning through PDV2 to the chloroplast surface to specify the site of ARC5 recruitment. Because orthologs of ARC6 occur in land plants, green algae, and cyanobacteria but PDV2 occurs only in land plants, the connection between ARC6 and PDV2 represents the evolution of a plant-specific adaptation to coordinate the assembly and activity of the endosymbiont- and host-derived plastid division components.

  2. Promoter-Terminator Gene Loops Affect Alternative 3'-End Processing in Yeast.

    PubMed

    Lamas-Maceiras, Mónica; Singh, Badri Nath; Hampsey, Michael; Freire-Picos, María A

    2016-04-22

    Many eukaryotic genes undergo alternative 3'-end poly(A)-site selection producing transcript isoforms with 3'-UTRs of different lengths and post-transcriptional fates. Gene loops are dynamic structures that juxtapose the 3'-ends of genes with their promoters. Several functions have been attributed to looping, including memory of recent transcriptional activity and polarity of transcription initiation. In this study, we investigated the relationship between gene loops and alternative poly(A)-site. Using the KlCYC1 gene of the yeast Kluyveromyces lactis, which includes a single promoter and two poly(A) sites separated by 394 nucleotides, we demonstrate in two yeast species the formation of alternative gene loops (L1 and L2) that juxtapose the KlCYC1 promoter with either proximal or distal 3'-end processing sites, resulting in the synthesis of short and long forms of KlCYC1 mRNA. Furthermore, synthesis of short and long mRNAs and formation of the L1 and L2 loops are growth phase-dependent. Chromatin immunoprecipitation experiments revealed that the Ssu72 RNA polymerase II carboxyl-terminal domain phosphatase, a critical determinant of looping, peaks in early log phase at the proximal poly(A) site, but as growth phase advances, it extends to the distal site. These results define a cause-and-effect relationship between gene loops and alternative poly(A) site selection that responds to different physiological signals manifested by RNA polymerase II carboxyl-terminal domain phosphorylation status. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  3. Restriction enzyme cutting site distribution regularity for DNA looping technology.

    PubMed

    Shang, Ying; Zhang, Nan; Zhu, Pengyu; Luo, Yunbo; Huang, Kunlun; Tian, Wenying; Xu, Wentao

    2014-01-25

    The restriction enzyme cutting site distribution regularity and looping conditions were studied systematically. We obtained the restriction enzyme cutting site distributions of 13 commonly used restriction enzymes in 5 model organism genomes through two novel self-compiled software programs. All of the average distances between two adjacent restriction sites fell sharply with increasing statistic intervals, and most fragments were 0-499 bp. A shorter DNA fragment resulted in a lower looping rate, which was also directly proportional to the DNA concentration. When the length was more than 500 bp, the concentration did not affect the looping rate. Therefore, the best known fragment length was longer than 500 bp, and did not contain the restriction enzyme cutting sites which would be used for digestion. In order to make the looping efficiencies reach nearly 100%, 4-5 single cohesive end systems were recommended to digest the genome separately. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Remediation System Evaluation, Douglas Road Landfill Superfund Site

    EPA Pesticide Factsheets

    The Douglas Road Landfill Superfund Site is located in St. Joseph County just north of Mishawaka,Indiana. The site consists of a 16-acre capped landfill located on an approximately 32-acre lot (includingthe land purchased in 1999 for a wetlands...

  5. GEOGRAPIC INFORMATION SYSTEMS IN DETERMINING ROAD TRAFFIC CRASH ANALYSIS IN IBADAN, NIGERIA.

    PubMed

    Rukewe, A; Taiwo, O J; Fatiregun, A A; Afuwape, O O; Alonge, T O

    2014-01-01

    Road traffic accidents are frequent in this environment, hence the need to determine the place of geographic information systems in the documentation of road traffic accidents. To investigate and document the variations in crash frequencies by types and across different road types in Ibadan, Nigeria. Road traffic accident data between January and June 2011 were obtained from the University College Hospital Emergency Department's trauma registry. All the traffic accidents were categorized into motor vehicular, motorbike and pedestrian crashes. Georeferencing of accident locations mentioned by patients was done using a combination of Google Earth and ArcGIS software. Nearest neighbor statistic, Moran's-I, Getis-Ord statistics, Student T-test, and ANOVA were used in investigating the spatial dynamics in crashes. Out of 600 locations recorded, 492 (82.0%) locations were correctly georeferenced. Crashes were clustered in space with motorbike crashes showing greatest clustering. There was significant difference in crashes between dual and non-dual carriage roads (P = 0.0001), but none between the inner city and the periphery (p = 0.115). However, significant variations also exist among the three categories analyzed (p = 0.004) and across the eleven Local Government Areas (P = 0.017). This study showed that the use of Geographic Information System can help in understanding variations in road traffic accident occurrence, while at the same time identifying locations and neighborhoods with unusually higher accidents frequency.

  6. [Emission Characteristics of Vehicle Exhaust in Beijing Based on Actual Traffic Flow Information].

    PubMed

    Fan, Shou-bin; Tian, Ling-di; Zhang, Dong-xu; Qu, Song

    2015-08-01

    The basic data of traffic volume, vehicle type constitute and speed on road networks in Beijing was obtained fly modei simulation and field survey. Based on actual traffic flow information and. emission factors data with temporal and spatial distribution features, emission inventory of motor vehicle exhaust in Beijing was built on the ArcGIS platform, meanwhile, the actual road emission characteristics and spatial distribution of the pollutant emissions were analyzed. The results showed that the proportion of passenger car was higher than 89% on each type of road in the urban, and the proportion of passenger car was the highest in suburban roads as well while the pickup truck, medium truck, heavy truck, motorbus, tractor and motorcycle also occupied a certain proportion. There was a positive correlation between the pollutant emission intensity and traffic volume, and the emission intensity was generally higher in daytime than nighttime, but the diurnal variation trend of PM emission was not clear for suburban roads and the emission intensity was higher in nighttime than daytime for highway. The emission intensities in urban area, south, southeast and northeast areas near urban were higher than those in the western and northern mountainous areas with lower density of road network. The ring roads in urban and highways in suburban had higher emission intensity because of the heavy traffic volume.

  7. Assessment of Sociodemographic and Geographic Disparities in Cancer Risk from Air Toxics in South Carolina

    PubMed Central

    Wilson, Sacoby; Burwell-Naney, Kristen; Jiang, Chengsheng; Zhang, Hongmei; Samantapudi, Ashok; Murray, Rianna; Dalemarre, Laura; Rice, LaShanta; Williams, Edith

    2015-01-01

    Populations of color and low-income communities are often disproportionately burdened by exposures to various environmental contaminants, including air pollution. Some air pollutants have carcinogenic properties that are particularly problematic in South Carolina (SC), a state that consistently has high rates of cancer mortality for all sites. The purpose of this study was to assess cancer risk disparities in SC by linking risk estimates from the U.S. Environmental Protection Agency’s 2005 National Air Toxics Assessment (NATA) with sociodemographic data from the 2000 US Census Bureau. Specifically, NATA risk data for varying risk categories were linked by tract ID and analyzed with sociodemographic variables from the 2000 census using R. The average change in cancer risk from all sources by sociodemographic variable was quantified using multiple linear regression models. Spatial methods were further employed using ArcGIS 10 to assess the distribution of all source risk and percent non-white at each census tract level. The relative risk estimates of the proportion of high cancer risk tracts (defined as the top 10% of cancer risk in SC) and their respective 95% confidence intervals (CIs) were calculated between the first and latter three quartiles defined by sociodemographic factors, while the variance in the percentage of high cancer risk between quartile groups was tested using Pearson’s chi-square. The average total cancer risk for SC was 26.8 people/million (ppl/million). The risk from on-road sources was approximately 5.8 ppl/million, higher than the risk from major, area, and non-road sources (1.8, 2.6, and 1.3 ppl/million), respectively. Based on our findings, addressing on-road sources may decrease the disproportionate cancer risk burden among low-income populations and communities of color in SC. PMID:26037107

  8. Flood-inundation maps for the Saluda River from Old Easley Bridge Road to Saluda Lake Dam near Greenville, South Carolina

    USGS Publications Warehouse

    Benedict, Stephen T.; Caldwell, Andral W.; Clark, Jimmy M.

    2013-01-01

    Digital flood-inundation maps for a 3.95-mile reach of the Saluda River from approximately 815 feet downstream from Old Easley Bridge Road to approximately 150 feet downstream from Saluda Lake Dam near Greenville, South Carolina, were developed by the U.S. Geological Survey (USGS). The inundation maps, which can be accessed through the USGS Flood Inundation Mapping Science Web site at http://water.usgs.gov/osw/flood_inundation/, depict estimates of the areal extent and depth of flooding corresponding to selected water levels (stages) at the USGS streamgage at Saluda River near Greenville, South Carolina (station 02162500). Current conditions at the USGS streamgage may be obtained through the National Water Information System Web site at http://waterdata.usgs.gov/sc/nwis/uv/?site_no=02162500&PARAmeter_cd=00065,00060,00062. The National Weather Service (NWS) forecasts flood hydrographs at many places that are often collocated with USGS streamgages. Forecasted peak-stage information is available on the Internet at the NWS Advanced Hydrologic Prediction Service (AHPS) flood-warning system Web site (http://water.weather.gov/ahps/) and may be used in conjunction with the maps developed in this study to show predicted areas of flood inundation.In this study, flood profiles were computed for the stream reach by means of a one-dimensional step-backwater model. The model was calibrated using the most current stage-streamflow relations at USGS streamgage station 02162500, Saluda River near Greenville, South Carolina. The hydraulic model was then used to determine water-surface profiles for flood stages at 1.0-foot intervals referenced to the streamgage datum and ranging from approximately bankfull to 2 feet higher than the highest recorded water level at the streamgage. The simulated water-surface profiles were then exported to a geographic information system, ArcGIS, and combined with a digital elevation model (derived from Light Detection and Ranging [LiDAR] data with a 0.6-foot vertical Root Mean Square Error [RMSE] and a 3.0-foot horizontal RMSE), using HEC-GeoRAS tools in order to delineate the area flooded at each water level. The availability of these maps, along with real-time stage data from the USGS streamgage station 02162500 and forecasted stream stages from the NWS, can provide emergency management personnel and residents with information that is critical during flood-response and flood-recovery activities, such as evacuations, road closures, and disaster declarations.

  9. Impact of secondary inorganic aerosol and road traffic at a suburban air quality monitoring station.

    PubMed

    Megido, L; Negral, L; Castrillón, L; Fernández-Nava, Y; Suárez-Peña, B; Marañón, E

    2017-03-15

    PM10 from a suburban site in the northwest of Spain was assessed using data from chemical determinations, meteorological parameters, aerosol maps and five-day back trajectories of air masses. Temporal variations in the chemical composition of PM10 were subsequently related to stationary/mobile local sources and long-range transport stemming from Europe and North Africa. The presence of secondary inorganic species (sulphates, nitrates and ammonium) in airborne particulate matter constituted one of the main focuses of this study. These chemical species formed 16.5% of PM10 on average, in line with other suburban background sites in Europe. However, a maximum of 47.8% of PM10 were recorded after several days under the influence of European air masses. Furthermore, the highest values of these three chemical species coincided with episodes of poor air circulation and influxes of air masses from Europe. The relationship between SO 4 2- and NH 4 + (R 2  = 0.57, p-value<0.01) was found to improve considerably in summer and spring (R 2  = 0.88 and R 2  = 0.87, respectively, p-value<0.01), whereas NO 3 - and NH 4 + (R 2  = 0.55, p-value<0.01) reproduced this pattern in winter (R 2  = 0.91, p-value<0.01). The application of a receptor model to the dataset led to the identification of notable apportionments due to road traffic and other types of combustion processes. In fact, large amounts of particulate matter were released to the atmosphere during episodes of biomass burning in forest fires. On isolated days, combustion was estimated to contribute up to 21.0 μg PM/m 3 (50.8% of PM10). The contribution from industrial processes to this source is also worth highlighting given the presence of Ni and Co in its profile. Furthermore, African dust outbreaks at the sampling site, characterised by an arc through the Atlantic Ocean, were usually associated with a higher concentration of Al 2 O 3 in PM10. Results evidenced the relevance of stationary (i.e., steelworks and thermal power station) and mobile sources in the air quality at the suburban site under study, with important apportionments of particulate matter coming from road traffic and as consequence of releasing precursor gases of secondary particles to the atmosphere. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. The Strength of an Ig Switch Region is Determined by its Ability to Drive R-loop Formation and its Number of WGCW Sites

    PubMed Central

    Zhang, Zheng Z.; Pannunzio, Nicholas R.; Han, Li; Hsieh, Chih-Lin; Yu, Kefei; Lieber, Michael R.

    2014-01-01

    SUMMARY R-loops exist at the murine IgH switch regions and possibly other locations, but their functional importance is unclear. In biochemical systems, R-loop initiation requires DNA sequence regions containing clusters of G nucleotides, but cellular studies have not been done. Here, we vary the G-clustering, total switch region length, and the number of target sites (WGCW sites for the activation-induced deaminase) at synthetic switch regions in a murine B cell line to determine the effect on class switch recombination (CSR). G-clusters increase CSR, regardless of their immediate proximity to the WGCW sites. This increase is accompanied by an increase in R-loop formation. CSR efficiency correlates better with the absolute number of WGCW sites in the switch region rather than the total switch region length or density of WGCW sites. Thus, the overall strength of the switch region depends on G-clusters, which initiate R-loop formation, and on the number of WGCW sites. PMID:25017067

  11. The arc arises: The links between volcanic output, arc evolution and melt composition

    NASA Astrophysics Data System (ADS)

    Brandl, Philipp A.; Hamada, Morihisa; Arculus, Richard J.; Johnson, Kyle; Marsaglia, Kathleen M.; Savov, Ivan P.; Ishizuka, Osamu; Li, He

    2017-03-01

    Subduction initiation is a key process for global plate tectonics. Individual lithologies developed during subduction initiation and arc inception have been identified in the trench wall of the Izu-Bonin-Mariana (IBM) island arc but a continuous record of this process has not previously been described. Here, we present results from International Ocean Discovery Program Expedition 351 that drilled a single site west of the Kyushu-Palau Ridge (KPR), a chain of extinct stratovolcanoes that represents the proto-IBM island arc, active for ∼25 Ma following subduction initiation. Site U1438 recovered 150 m of oceanic igneous basement and ∼1450 m of overlying sediments. The lower 1300 m of these sediments comprise volcaniclastic gravity-flow deposits shed from the evolving KPR arc front. We separated fresh magmatic minerals from Site U1438 sediments, and analyzed 304 glass (formerly melt) inclusions, hosted by clinopyroxene and plagioclase. Compositions of glass inclusions preserve a temporal magmatic record of the juvenile island arc, complementary to the predominant mid-Miocene to recent activity determined from tephra layers recovered by drilling in the IBM forearc. The glass inclusions record the progressive transition of melt compositions dominated by an early 'calc-alkalic', high-Mg andesitic stage to a younger tholeiitic stage over a time period of 11 Ma. High-precision trace element analytical data record a simultaneously increasing influence of a deep subduction component (e.g., increase in Th vs. Nb, light rare earth element enrichment) and a more fertile mantle source (reflected in increased high field strength element abundances). This compositional change is accompanied by increased deposition rates of volcaniclastic sediments reflecting magmatic output and maturity of the arc. We conclude the 'calc-alkalic' stage of arc evolution may endure as long as mantle wedge sources are not mostly advected away from the zones of arc magma generation, or the rate of wedge replenishment by corner flow does not overwhelm the rate of magma extraction.

  12. 77 FR 2911 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-20

    .../Sodyeco Superfund Site (Site) located at 11701 Mount Holly Road in Charlotte, North Carolina, from the... appropriate response actions under CERCLA, other than operation, maintenance, and five-year reviews, have been...: Martin-Marietta/Sodyeco Superfund Site (Site) located at 11701 Mount Holly Road in Charlotte, North...

  13. Evaluation of microwave traffic detector at the Chemawa Road/Interstate 5 interchange: final report.

    DOT National Transportation Integrated Search

    2002-04-01

    In 2001, the Oregon Department of Transportation installed a microwave traffic detection sensor, and compared its performance to conventional inductive traffic loops. The objective of the study was to evaluate the capabilities of the microwave tra...

  14. LOOKING NORTH AT ENTRY WEST OF BEDROOM WING. Stereopair No. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LOOKING NORTH AT ENTRY WEST OF BEDROOM WING. Stereopair No. B1983-300-11, Neg. Nos. L6 & R5 - Lake Hotel, .5 mile East of Grand Loop Road & 1.3 miles southwest of Lake Junction, Lake, Teton County, WY

  15. LOOKING SOUTHEAST TOWARDS WEST END OF DINING ROOM. Stereopair No. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LOOKING SOUTHEAST TOWARDS WEST END OF DINING ROOM. Stereopair No. B1983-300-2, Neg. Nos. L3 & R4 - Lake Hotel, .5 mile East of Grand Loop Road & 1.3 miles southwest of Lake Junction, Lake, Teton County, WY

  16. LOOKING NORTH TOWARDS DINING ROOM AND PORTICO. Stereopair No. B19833004, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LOOKING NORTH TOWARDS DINING ROOM AND PORTICO. Stereopair No. B1983-300-4, Neg. Nos. L2 & R1 - Lake Hotel, .5 mile East of Grand Loop Road & 1.3 miles southwest of Lake Junction, Lake, Teton County, WY

  17. Loop engineering reveals the importance of active-site-decorating loops and gating residue in substrate affinity modulation of arginine deiminase (an anti-tumor enzyme).

    PubMed

    Cheng, Feng; Yang, Jianhua; Bocola, Marco; Schwaneberg, Ulrich; Zhu, Leilei

    2018-05-05

    Protein engineering of enzyme loop regions is an effective strategy to improve enzymatic properties. Previous studies that aimed to boost the activity of PpADI (an arginine deiminase from Pseudomonas plecoglossicida) under physiological conditions yielded several significantly improved variants that harbor substitutions predominantly located in active-site-decorating loops. A multi-site saturation mutagenesis at four positions in loop 1 (37, 38, 42, and 43) and three positions in loop 4 (402, 403, and 404) was performed to elucidate the importance of these loops in modulating the substrate affinity of PpADI. The identified "best" variant (M6-L1-4) showed a decreased S 0.5 ('K M ') of 0.48 mM compared with the parent M6 (0.81 mM). Subsequently, a rational design to recombine beneficial substitutions within loops 1 and 4 yielded variant L6 with a substantially decreased S 0.5 value (0.17 mM). A comprehensive simulation analysis resulted in a conclusion that high loop flexibility (especially the gating residue Arg400) is beneficial for substrate affinity due to less efficient blocking of the active site. Copyright © 2018 Elsevier Inc. All rights reserved.

  18. Dynamics of the active site loops in catalyzing aminoacylation reaction in seryl and histidyl tRNA synthetases.

    PubMed

    Dutta, Saheb; Kundu, Soumya; Saha, Amrita; Nandi, Nilashis

    2018-03-01

    Aminoacylation reaction is the first step of protein biosynthesis. The catalytic reorganization at the active site of aminoacyl tRNA synthetases (aaRSs) is driven by the loop motions. There remain lacunae of understanding concerning the catalytic loop dynamics in aaRSs. We analyzed the functional loop dynamics in seryl tRNA synthetase from Methanopyrus kandleri ( mk SerRS) and histidyl tRNA synthetases from Thermus thermophilus ( tt HisRS), respectively, using molecular dynamics. Results confirm that the motif 2 loop and other active site loops are flexible spots within the catalytic domain. Catalytic residues of the loops form a network of interaction with the substrates to form a reactive state. The loops undergo transitions between closed state and open state and the relaxation of the constituent residues occurs in femtosecond to nanosecond time scale. Order parameters are higher for constituent catalytic residues which form a specific network of interaction with the substrates to form a reactive state compared to the Gly residues within the loop. The development of interaction is supported from mutation studies where the catalytic domain with mutated loop exhibits unfavorable binding energy with the substrates. During the open-close motion of the loops, the catalytic residues make relaxation by ultrafast librational motion as well as fast diffusive motion and subsequently relax rather slowly via slower diffusive motion. The Gly residues act as a hinge to facilitate the loop closing and opening by their faster relaxation behavior. The role of bound water is analyzed by comparing implicit solvent-based and explicit solvent-based simulations. Loops fail to form catalytically competent geometry in absence of water. The present result, for the first time reveals the nature of the active site loop dynamics in aaRS and their influence on catalysis.

  19. Non-Destructive Survey of Archaeological Sites Using Airborne Laser Scanning and Geophysical Applications

    NASA Astrophysics Data System (ADS)

    Poloprutský, Z.; Cejpová, M.; Němcová, J.

    2016-06-01

    This paper deals with the non-destructive documentation of the "Radkov" (Svitavy district, Czech Republic) archaeological site. ALS, GPR and land survey mapping will be used for the analysis. The fortified hilltop settlement "Radkov" is an immovable historical monument with preserved relics of anthropogenic origin in relief. Terrain reconnaissance can identify several accentuated objects on site. ALS enables identification of poorly recognizable archaeological objects and their contexture in the field. Geophysical survey enables defunct objects identification. These objects are hidden below the current ground surface and their layout is crucial. Land survey mapping provides technical support for ALS and GPR survey. It enables data georeferencing in geodetic reference systems. GIS can then be used for data analysis. M. Cejpová and J. Němcová have studied this site over a long period of time. In 2012 Radkov was surveyed using ALS in the project "The Research of Ancient Road in Southwest Moravia and East Bohemia". Since 2015 the authors have been examining this site. This paper summarises the existing results of the work of these authors. The digital elevation model in the form of a grid (GDEM) with a resolution 1 m of 2012 was the basis for this work. In 2015 the survey net, terrain reconnaissance and GPR survey of two archaeological objects were done at the site. GDEM was compared with these datasets. All datasets were processed individually and its results were compared in ArcGIS. This work was supported by the Grant Agency of the CTU in Prague, grant No. SGS16/063/OHK1/1T/11.

  20. 75 FR 2487 - Foreign-Trade Zone 176-Rockford, IL; Application for Reorganization/Expansion Under Alternative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ... parcels located in and around the Chicago Rockford International Airport (including the [[Page 2488...) and a parcel located at 1635 New Milford School Road/1129 18th Avenue, Rockford; Site 3: (566 acres... Road and Gurler Road, DeKalb; Site 11: (46 acres) Loves Park Corporate Center, located at Bell School...

  1. Sedimentation associated with forest road surfacing in a bottomland hardwood ecosystem

    Treesearch

    Robert B. Rummer; Bryce Stokes; Graeme Lockaby

    1997-01-01

    Access systems are a necessary element of resource production in bottomland hardwood sites. However, road building may have a detrimental effect on hydrologic function of the site. This report describes initial results of a study designed to examine the effect of different road surfacing treatments on water quality.Four Surfacing treatments installed on two...

  2. Geospatial Estimates of Road Salt Usage Across a Gradient of Urbanizing Watersheds in Southern Ontario:Thesis for Masters in Spatial Analysis (MSA)

    NASA Astrophysics Data System (ADS)

    Giberson, G. K.; Oswald, C.

    2015-12-01

    In areas affected by snow, chloride (Cl) salts are widely used as a de-icing agent to improve road conditions. While the improvement in road safety is indisputable, there are environmental consequences to local aquatic ecosystems. In many waterways, Cl concentrations have been increasing since the early 1990s, often exceeding national water quality guidelines. To determine the quantity of Cl that is accumulating in urban and urbanizing watersheds, accurate estimates of road salt usage at the watershed-scale are needed. The complex jurisdictional control over road salt application in southern Ontario lends itself to a geospatial approach for calculating Cl inputs to improve the accuracy of watershed-scale Cl mass balance estimates. This study will develop a geospatial protocol for combining information on road salt applications and road network areas to refine watershed-scale Cl inputs, as well as assess spatiotemporal patterns in road salt application across the southern Ontario study region. The overall objective of this project is to use geospatial methods (predominantly ArcGIS) to develop high-accuracy estimates of road salt usage in urbanizing watersheds in southern Ontario. Specifically, the aims will be to map and summarize the types and areas ("lane-lengths") of roadways in each watershed that have road salt applied to them, to determine the most appropriate source(s) of road salt usage data for each watershed, taking into consideration multiple levels of jurisdiction (e.g. municipal, regional, provincial), to calculate and summarize sub-watershed and watershed-scale road salt usage estimates for multiple years, and to analyze intra-watershed spatiotemporal patterns of road salt usage, especially focusing on impervious surfaces. These analyses will recommend areas of concern exacerbated by high-levels of road salt distribution; recommendations around modifying on-the-ground operations will be the next step in helping to correct these issues.

  3. A video-based real-time adaptive vehicle-counting system for urban roads.

    PubMed

    Liu, Fei; Zeng, Zhiyuan; Jiang, Rong

    2017-01-01

    In developing nations, many expanding cities are facing challenges that result from the overwhelming numbers of people and vehicles. Collecting real-time, reliable and precise traffic flow information is crucial for urban traffic management. The main purpose of this paper is to develop an adaptive model that can assess the real-time vehicle counts on urban roads using computer vision technologies. This paper proposes an automatic real-time background update algorithm for vehicle detection and an adaptive pattern for vehicle counting based on the virtual loop and detection line methods. In addition, a new robust detection method is introduced to monitor the real-time traffic congestion state of road section. A prototype system has been developed and installed on an urban road for testing. The results show that the system is robust, with a real-time counting accuracy exceeding 99% in most field scenarios.

  4. A video-based real-time adaptive vehicle-counting system for urban roads

    PubMed Central

    2017-01-01

    In developing nations, many expanding cities are facing challenges that result from the overwhelming numbers of people and vehicles. Collecting real-time, reliable and precise traffic flow information is crucial for urban traffic management. The main purpose of this paper is to develop an adaptive model that can assess the real-time vehicle counts on urban roads using computer vision technologies. This paper proposes an automatic real-time background update algorithm for vehicle detection and an adaptive pattern for vehicle counting based on the virtual loop and detection line methods. In addition, a new robust detection method is introduced to monitor the real-time traffic congestion state of road section. A prototype system has been developed and installed on an urban road for testing. The results show that the system is robust, with a real-time counting accuracy exceeding 99% in most field scenarios. PMID:29135984

  5. 76 FR 41751 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... Hipps Road Landfill Superfund Site AGENCY: Environmental Protection Agency. ACTION: Proposed rule... Hipps Road Landfill Superfund Site (Site) located in Jacksonville, Florida, from the National Priorities..., have determined that all appropriate response actions under CERCLA, other than operation, maintenance...

  6. Does TRACE Resolve Isothermal Coronal Loops?

    NASA Astrophysics Data System (ADS)

    Weber, Mark A.; Schmelz, J.; Kashyap, V.; Roames, J.

    2006-06-01

    Historically, increasing resolution of solar data has revealed ever smaller length scales for both the thermodynamics and the magnetic structure of the corona. Furthermore, the dynamics there are governed by magnetohydrodynamic processes which are difficult to observe or model. Recent results in the literature suggest that some coronal loops with cross-sections near the resolution limits of the Transition Region and Coronal Explorer (pixel size = 0.5 arc-seconds, or approx. 360 km) are, in fact, isothermally homogeneous and thus may be identified as elementary loop strands. This poster presents some ongoing work that applies state-of-the-art estimation of differential emission measures in order to evaluate these claims for a sample of loops. We find that the data give no evidence to prefer the "isothermal" hypothesis over the "multithermal" hypothesis. The authors are supported by the following funds: contract SP02H820IR to the Lockheed-Martin Corp.; NSF grant ATM-0402729; NASA grant NNG05GE68G; and NASA contracts NAS8-39073 and NAS8-03060.

  7. Boron isotope fractionation in magma via crustal carbonate dissolution

    PubMed Central

    Deegan, Frances M.; Troll, Valentin R.; Whitehouse, Martin J.; Jolis, Ester M.; Freda, Carmela

    2016-01-01

    Carbon dioxide released by arc volcanoes is widely considered to originate from the mantle and from subducted sediments. Fluids released from upper arc carbonates, however, have recently been proposed to help modulate arc CO2 fluxes. Here we use boron as a tracer, which substitutes for carbon in limestone, to further investigate crustal carbonate degassing in volcanic arcs. We performed laboratory experiments replicating limestone assimilation into magma at crustal pressure-temperature conditions and analysed boron isotope ratios in the resulting experimental glasses. Limestone dissolution and assimilation generates CaO-enriched glass near the reaction site and a CO2-dominated vapour phase. The CaO-rich glasses have extremely low δ11B values down to −41.5‰, reflecting preferential partitioning of 10B into the assimilating melt. Loss of 11B from the reaction site occurs via the CO2 vapour phase generated during carbonate dissolution, which transports 11B away from the reaction site as a boron-rich fluid phase. Our results demonstrate the efficacy of boron isotope fractionation during crustal carbonate assimilation and suggest that low δ11B melt values in arc magmas could flag shallow-level additions to the subduction cycle. PMID:27488228

  8. Boron isotope fractionation in magma via crustal carbonate dissolution

    NASA Astrophysics Data System (ADS)

    Deegan, Frances M.; Troll, Valentin R.; Whitehouse, Martin J.; Jolis, Ester M.; Freda, Carmela

    2016-08-01

    Carbon dioxide released by arc volcanoes is widely considered to originate from the mantle and from subducted sediments. Fluids released from upper arc carbonates, however, have recently been proposed to help modulate arc CO2 fluxes. Here we use boron as a tracer, which substitutes for carbon in limestone, to further investigate crustal carbonate degassing in volcanic arcs. We performed laboratory experiments replicating limestone assimilation into magma at crustal pressure-temperature conditions and analysed boron isotope ratios in the resulting experimental glasses. Limestone dissolution and assimilation generates CaO-enriched glass near the reaction site and a CO2-dominated vapour phase. The CaO-rich glasses have extremely low δ11B values down to -41.5‰, reflecting preferential partitioning of 10B into the assimilating melt. Loss of 11B from the reaction site occurs via the CO2 vapour phase generated during carbonate dissolution, which transports 11B away from the reaction site as a boron-rich fluid phase. Our results demonstrate the efficacy of boron isotope fractionation during crustal carbonate assimilation and suggest that low δ11B melt values in arc magmas could flag shallow-level additions to the subduction cycle.

  9. Boron isotope fractionation in magma via crustal carbonate dissolution.

    PubMed

    Deegan, Frances M; Troll, Valentin R; Whitehouse, Martin J; Jolis, Ester M; Freda, Carmela

    2016-08-04

    Carbon dioxide released by arc volcanoes is widely considered to originate from the mantle and from subducted sediments. Fluids released from upper arc carbonates, however, have recently been proposed to help modulate arc CO2 fluxes. Here we use boron as a tracer, which substitutes for carbon in limestone, to further investigate crustal carbonate degassing in volcanic arcs. We performed laboratory experiments replicating limestone assimilation into magma at crustal pressure-temperature conditions and analysed boron isotope ratios in the resulting experimental glasses. Limestone dissolution and assimilation generates CaO-enriched glass near the reaction site and a CO2-dominated vapour phase. The CaO-rich glasses have extremely low δ(11)B values down to -41.5‰, reflecting preferential partitioning of (10)B into the assimilating melt. Loss of (11)B from the reaction site occurs via the CO2 vapour phase generated during carbonate dissolution, which transports (11)B away from the reaction site as a boron-rich fluid phase. Our results demonstrate the efficacy of boron isotope fractionation during crustal carbonate assimilation and suggest that low δ(11)B melt values in arc magmas could flag shallow-level additions to the subduction cycle.

  10. Integrated Testing of a 4-Bed Molecular Sieve and a Temperature-Swing Adsorption Compressor for Closed-Loop Air Revitalization

    NASA Technical Reports Server (NTRS)

    Knox, James C.; Mulloth, Lila M.; Affleck, David L.

    2004-01-01

    Accumulation and subsequent compression of carbon dioxide that is removed from space cabin are two important processes involved in a closed-loop air revitalization scheme of the International Space Station (ISS). The 4-Bed Molecular Sieve (4BMS) of ISS currently operates in an open loop mode without a compressor. This paper reports the integrated 4BMS and liquid-cooled TSAC testing conducted during the period of March 3 to April 18, 2003. The TSAC prototype was developed at NASA Ames Research Center (ARC). The 4BMS was modified to a functionally flight-like condition at NASA Marshall Space Flight Center (MSFC). Testing was conducted at MSFC. The paper provides details of the TSAC operation at various CO2 loadings and corresponding performance of CDRA.

  11. Control of a 30 cm diameter mercury bombardment thruster

    NASA Technical Reports Server (NTRS)

    Terdan, F. F.; Bechtel, R. T.

    1973-01-01

    Increased thruster performance has made closed-loop automatic control more difficult than previously. Specifically, high perveance optics tend to make reliable recycling more difficult. Control logic functions were established for three automatic modes of operation of a 30-cm thruster using a power conditioner console with flight-like characteristics. The three modes provide (1) automatic startup to reach thermal stability, (2) steady-state closed-loop control, and (3) the reliable recycling of the high voltages following an arc breakdown to reestablish normal operation. Power supply impedance characteristics necessary for stable operation and the effect of the magnetic baffle on the reliable recycling was studied.

  12. Comparative metagenomics approaches to characterize the soil fungal communities of western coastal region, Saudi Arabia.

    PubMed

    Moussa, Tarek A A; Al-Zahrani, Hassan S; Almaghrabi, Omar A; Abdelmoneim, Tamer S; Fuller, Michael P

    2017-01-01

    A total of 145007 reads were obtained from pyrosequencing for all the 4 samples. The total count ranged from 11,301,014 (Mecca old road) to 23,503,512 bp (Thuwal). A total of 460 fungal species belonging to 133 genera, 58 families, 33 orders, 13 classes and 4 phyla was identified across the four sites. The most abundant phylum at all four sites was Ascomycota followed by Basidiomycota. Four phyla (Ascomycota-99.31%, Basidiomycota-0.59%, Chytridiomycota-0.04%, Glomeromycota-0.03%) were detected in Khulais. Except for Glomeromycota, all phyla were detected at Mecca old road (Ascomycota-74.26%, Basidiomycota-25.71%, Chytridiomycota-0.01%) and Thuwal (Ascomycota-99.59%, Basidiomycota-0.40%, Chytridiomycota-0.002%); while only Ascomycota-90.98% and Basidiomycota-9.01% were detected in Asfan road. At the class level, Sordariomycetes was predominantly observed at Asfan road-59.88%, Khulais-68.26% and Thuwal-94.84%; while Pezizomycetes was dominant at Mecca old road-56.01%, was absent at Asfan road. Agaricomycetes was present only at Mecca old road-25.73%; while Tremellomycetes-5.77%, Malasseizomycetes-2.13% and Microbotryomycetes-1.10% were found only at Asfan road. The phylogenetic trees revealed that clear genus level differences are visible across all the four sites, with an overall predominance of Thielavia followed by Madurella, Aspergillus, and Gelasinospora. Chaetomium sp., Aspergillus caespitosus and Aspergillus sp. were found in moderate (Mecca old road and Thuwal) to abundant (Asfan road and Khulais) quantities. Thielavia sp., Thielavia hyalocarpa and Madurella sp. are found in moderate quantities at Khulais and Mecca old road, while in abundant levels at Asfan road and Thuwal. Fusarium equisati and F. oxysporum were detected at Thuwal and Khulais. Sordaria araneosa was present at Khulais, while Malasseiza globosa species was detected in moderate quantities across all sites except Khulais.

  13. Visualizing Active-Site Dynamics in Single Crystals of HePTP: Opening of the WPD Loop Involves Coordinated Movement of the E Loop

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D Critton; L Tautz; R Page

    2011-12-31

    Phosphotyrosine hydrolysis by protein tyrosine phosphatases (PTPs) involves substrate binding by the PTP loop and closure over the active site by the WPD loop. The E loop, located immediately adjacent to the PTP and WPD loops, is conserved among human PTPs in both sequence and structure, yet the role of this loop in substrate binding and catalysis is comparatively unexplored. Hematopoietic PTP (HePTP) is a member of the kinase interaction motif (KIM) PTP family. Compared to other PTPs, KIM-PTPs have E loops that are unique in both sequence and structure. In order to understand the role of the E loopmore » in the transition between the closed state and the open state of HePTP, we identified a novel crystal form of HePTP that allowed the closed-state-to-open-state transition to be observed within a single crystal form. These structures, which include the first structure of the HePTP open state, show that the WPD loop adopts an 'atypically open' conformation and, importantly, that ligands can be exchanged at the active site, which is critical for HePTP inhibitor development. These structures also show that tetrahedral oxyanions bind at a novel secondary site and function to coordinate the PTP, WPD, and E loops. Finally, using both structural and kinetic data, we reveal a novel role for E-loop residue Lys182 in enhancing HePTP catalytic activity through its interaction with Asp236 of the WPD loop, providing the first evidence for the coordinated dynamics of the WPD and E loops in the catalytic cycle, which, as we show, is relevant to multiple PTP families.« less

  14. TECHNOLOGY EVALUATION REPORT, SITE PROGRAM DEMONSTRATION TEST: SHIRCO PILOT-SCALE INFRARED INCINERATION SYSTEM ROSE TOWNSHIP DEMODE ROAD SUPERFUND SITE - VOLUME II

    EPA Science Inventory

    The performance of the Shirco pilot-scale infrared thermal destruction system has been evaluated at the Rose Township, Demode Road Superfund Site and is presented in the report. The waste tested consisted of solvents, organics and heavy metals in an illegal dump site. Volume I gi...

  15. 8. COLLAPSED AND SCATTERED BUILDING ON FLOOR OF PIT, WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. COLLAPSED AND SCATTERED BUILDING ON FLOOR OF PIT, WITH PILE OF RHYOLITE BOULDERS IN BACKGROUND, VIEW TO SOUTH - Iron Springs Quarry, 150 feet west of Grand Loop Road, 20 miles east of U.S. Highway 287, West Thumb, Teton County, WY

  16. 34. Site Plan: Fort Custer Air Force Station, Fort Custer, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. Site Plan: Fort Custer Air Force Station, Fort Custer, Michigan, Modification of Electrical Distribution, General Site Plan, USACOE, no date. - Fort Custer Military Reservation, P-67 Radar Station, .25 mile north of Dickman Road, east of Clark Road, Battle Creek, Calhoun County, MI

  17. 76 FR 81904 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... Road Landfill Superfund Site AGENCY: Environmental Protection Agency. ACTION: Proposed rule; notice of... Delete the Hipps Road Landfill Superfund Site (Site) located in Jacksonville, Florida, from the National..., have determined that all appropriate response actions under CERCLA, other than operation, maintenance...

  18. Dynamic path planning for autonomous driving on various roads with avoidance of static and moving obstacles

    NASA Astrophysics Data System (ADS)

    Hu, Xuemin; Chen, Long; Tang, Bo; Cao, Dongpu; He, Haibo

    2018-02-01

    This paper presents a real-time dynamic path planning method for autonomous driving that avoids both static and moving obstacles. The proposed path planning method determines not only an optimal path, but also the appropriate acceleration and speed for a vehicle. In this method, we first construct a center line from a set of predefined waypoints, which are usually obtained from a lane-level map. A series of path candidates are generated by the arc length and offset to the center line in the s - ρ coordinate system. Then, all of these candidates are converted into Cartesian coordinates. The optimal path is selected considering the total cost of static safety, comfortability, and dynamic safety; meanwhile, the appropriate acceleration and speed for the optimal path are also identified. Various types of roads, including single-lane roads and multi-lane roads with static and moving obstacles, are designed to test the proposed method. The simulation results demonstrate the effectiveness of the proposed method, and indicate its wide practical application to autonomous driving.

  19. Damage Assessment for Disaster Relief Efforts in Urban Areas Using Optical Imagery and LiDAR Data

    NASA Astrophysics Data System (ADS)

    Bahr, Thomas

    2014-05-01

    Imagery combined with LiDAR data and LiDAR-derived products provides a significant source of geospatial data which is of use in disaster mitigation planning. Feature rich building inventories can be constructed from tools with 3D rooftop extraction capabilities, and two dimensional outputs such as DSMs and DTMs can be used to generate layers to support routing efforts in Spatial Analyst and Network Analyst workflows. This allows us to leverage imagery and LiDAR tools for disaster mitigation or other scenarios. Software such as ENVI, ENVI LiDAR, and ArcGIS® Spatial and Network Analyst can therefore be used in conjunction to help emergency responders route ground teams in support of disaster relief efforts. This is exemplified by a case study against the background of the magnitude 7.0 earthquake that struck Haiti's capital city of Port-au-Prince on January 12, 2010. Soon after, both LiDAR data and an 8-band WorldView-2 scene were collected to map the disaster zone. The WorldView-2 scene was orthorectified and atmospherically corrected in ENVI prior to use. ENVI LiDAR was used to extract the DSM, DTM, buildings, and debris from the LiDAR data point cloud. These datasets provide a foundation for the 2D portion of the analysis. As the data was acquired over an area of dense urbanization, the majority of ground surfaces are roads, and standing buildings and debris are actually largely separable on the basis of elevation classes. To extract the road network of Port-au-Prince, the LiDAR-based feature height information was fused with the WorldView-2 scene, using ENVI's object-based feature extraction approach. This road network was converted to a network dataset for further analysis by the ArcGIS Network Analyst. For the specific case of Haiti, the distribution of blue tarps, used as accommodations for refugees, provided a spectrally distinct target. Pure blue tarp pixel spectra were selected from the WorldView-2 scene and input as a reference into ENVI's Spectral Angle Mapper (SAM) classification routine, together with a water-shadow mask to prevent false positives. The resulting blue tarp shape file was input into the ArcGIS Point Density tool, a feature of the Spatial Analyst toolbox. The final distribution map shows the density of blue tarps in Port-au-Prince and can be used to roughly delineate camps of refugees. Analogous, a debris density map was generated after separating the debris elevation class. The combination of this debris density map with the road network allowed to construct an intact road network of Port-au-Prince within the ArcGIS Network Analyst. Moderate density debris was used as a cost-increase barrier feature of the network dataset, and high density debris was used as a total obstruction barrier feature. Based on this information, two hypothetical routing scenarios were analyzed. One involved routing a ground team between two different refugee concentration zones. For the other, potential helicopter landing zones were computed from the LiDAR-derived products and added as facility features to the Network Analyst. Routes from the helicopter landing zones to refugee concentration access points were solved using closest facility logic, again making use of the obstructed network.

  20. Identifying unstable sites on logging roads

    Treesearch

    R. M. Rice; J. Lewis

    1986-01-01

    Logging roads are an important source of forestry-related erosion. The amount of erosion on a forest road is determined by the interaction between how the road is constructed and maintained and the environment in which it is built. The roads in this study were constructed with large bulldozers, and most excavated material was sidecast. The roads studied were...

  1. A study of the landslide potential along the mountain road using environmental indices

    NASA Astrophysics Data System (ADS)

    Lin, C. Y.

    2014-12-01

    Utilization of slope land in recent years is rapid as a result of the dense population and limit of land resources in Taiwan. Therefore, mountain road plays an essential role for the necessity of human life. However, landslide disaster resulting in road failure occurred frequently in Taiwan on the slope land due to earthquake and typhoon. Previous studies found that the extreme rainfall coupled with the property of fragile geology could cause landslide. Nevertheless, the landslide occurrence might be affected by the drainage of the road side ditches. Taiwan Highway No.21 in Chi-Shan watershed and the forest roads located in Xiao-Lin Village, which failure during the hit of Typhoon Morakot in 2009, were selected for exploring the potential of vulnerable to landslides. Topographic Wetness Index (TWI) and Road Curvature (RC) were extracted along the road to indicate the potential sites which are vulnerable to slope failure. The surface runoff diverted by the road side ditches could spoil the sites with high RC due to the straight movement characteristics of the diverted runoff and cause the downslope collapse. The sites with higher mean value and lower standard deviation of Normalized Difference Vegetation Index (NDVI) derived from the SPOT imagery taken in dry and/or rainy seasons could be implied as the vegetation stands showing highly buffer effects in environmental stress due to having deeper soil layer, and are hardly interfered by the drought. The stands located in such sites once collapsed are often resulting in huge volumes of debris. Drainage Density (DD) index could be applied as the degrees of geologic fragile in the slope land. A road across the sites with higher mean value and lower standard deviation of NDVI and/or higher DD should be paid more attention because of having highly vulnerable to deep seated landslide. This study is focusing on extracting and analyzing the environmental indices such as TWI, RC, NDVI and DD for exploring the slope stability along the mountain road. The results could be used as the references of related authorities for understanding the potential landslides along a road.

  2. A retrospective diagnosis of epilepsy in three historical figures: St Paul, Joan of Arc and Socrates.

    PubMed

    Muhammed, Louwai

    2013-11-01

    It has been suggested that undiagnosed epilepsy profoundly influenced the lives of several key figures in history. Historical sources recounting strange voices and visions may in fact have been describing manifestations of epileptic seizures rather than more supernatural phenomena. Well-documented accounts of such experiences exist for three individuals in particular: Socrates, St Paul and Joan of Arc. The great philosopher Socrates described a 'daimonion' that would visit him throughout his life. This daimonion may have represented recurrent simple partial seizures, while the peculiar periods of motionlessness for which Socrates was well known may have been the result of co-existing complex partial seizures. St Paul's religious conversion on the Road to Damascus may have followed a temporal lobe seizure which would account for the lights, voices, blindness and even the religious ecstasy he described. Finally, Joan of Arc gave a detailed narrative on the voices she heard from childhood during her Trial of Condemnation. Her auditory hallucinations appear to follow sudden acoustic stimuli in a way reminiscent of idiopathic partial epilepsy with auditory features. By analysing passages from historical texts, it is possible to argue that Socrates, St Paul and Joan of Arc each had epilepsy.

  3. Functional and structural characterization of the pentapeptide insertion of Theileria annulata lactate dehydrogenase by site-directed mutagenesis, comparative modeling and molecular dynamics simulations.

    PubMed

    Erdemir, Aysegul; Mutlu, Ozal

    2017-06-01

    Lactate dehydrogenase (LDH) is an important metabolic enzyme in glycolysis and it has been considered as the main energy source in many organisms including apicomplexan parasites. Differences at the active site loop of the host and parasite LDH's makes this enzyme an attractive target for drug inhibitors. In this study, five amino acid insertions in the active site pocket of Theileria annulata LDH (TaLDH) were deleted by PCR-based site-directed mutagenesis, expression and activity analysis of mutant and wild type TaLDH enzymes were performed. Removal of the insertion at the active site loop caused production of an inactive enzyme. Furthermore, structures of wild and mutant enzymes were predicted by comparative modeling and the importance of the insertions at the active site loop were also assigned by molecular docking and dynamics simulations in order to evaluate essential role of this loop for the enzymatic activity. Pentapeptide insertion removal resulted in loss of LDH activity due to deletion of Trp96 and conformational change of Arg98 because of loop instability. Analysis of wild type and mutant enzymes with comparative molecular dynamics simulations showed that the fluctuations of the loop residues increase in mutant enzyme. Together with in silico studies, in vitro results revealed that active site loop has a vital role in the enzyme activity and our findings promise hope for the further drug design studies against theileriosis and other apicomplexan parasite diseases. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. LBSizeCleav: improved support vector machine (SVM)-based prediction of Dicer cleavage sites using loop/bulge length.

    PubMed

    Bao, Yu; Hayashida, Morihiro; Akutsu, Tatsuya

    2016-11-25

    Dicer is necessary for the process of mature microRNA (miRNA) formation because the Dicer enzyme cleaves pre-miRNA correctly to generate miRNA with correct seed regions. Nonetheless, the mechanism underlying the selection of a Dicer cleavage site is still not fully understood. To date, several studies have been conducted to solve this problem, for example, a recent discovery indicates that the loop/bulge structure plays a central role in the selection of Dicer cleavage sites. In accordance with this breakthrough, a support vector machine (SVM)-based method called PHDCleav was developed to predict Dicer cleavage sites which outperforms other methods based on random forest and naive Bayes. PHDCleav, however, tests only whether a position in the shift window belongs to a loop/bulge structure. In this paper, we used the length of loop/bulge structures (in addition to their presence or absence) to develop an improved method, LBSizeCleav, for predicting Dicer cleavage sites. To evaluate our method, we used 810 empirically validated sequences of human pre-miRNAs and performed fivefold cross-validation. In both 5p and 3p arms of pre-miRNAs, LBSizeCleav showed greater prediction accuracy than PHDCleav did. This result suggests that the length of loop/bulge structures is useful for prediction of Dicer cleavage sites. We developed a novel algorithm for feature space mapping based on the length of a loop/bulge for predicting Dicer cleavage sites. The better performance of our method indicates the usefulness of the length of loop/bulge structures for such predictions.

  5. 76 FR 81840 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... Road Landfill Superfund Site AGENCY: Environmental Protection Agency. ACTION: Direct final rule... Deletion of the Hipps Road Landfill Superfund Site (Site), located in Jacksonville, Florida, from the... than operation, maintenance, and five-year reviews have been completed. However, this deletion does not...

  6. 76 FR 41719 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... Road Landfill Superfund Site AGENCY: Environmental Protection Agency. ACTION: Direct final rule... Deletion of the Hipps Road Landfill Superfund Site (Site), located in Jacksonville, Florida, from the... than operation, maintenance, and five-year reviews have been completed. However, this deletion does not...

  7. SHIRCO PILOT-SCALE INFRARED INCINERATION SYSTEM AT THE ROSE TOWNSHIP DEMODE ROAD SUPERFUND SITE

    EPA Science Inventory

    Under the Superfund Innovative Technology Evaluation or SITE Program, an evaluation was made of the Shirco Pilot-Scale Infrared Incineration System during 17 separate test runs under varying operating conditions. The tests were conducted at the Demode Road Superfund site in Ros...

  8. Tectonic reconstruction of the Panama arc using paleomagnetic, geochronology and thermochronologic data

    NASA Astrophysics Data System (ADS)

    Montes, C.; Bayona, G.; Cardona, A.; Pardo, A.; Nova, G.; Montano, P.

    2013-05-01

    A recent update of the geochronologic and mapping database of the Isthmus of Panama suggests that the Isthmus represents an arc that was left-laterally fragmented between 38 and 28 Ma, and then oroclinally bent. This was hypothesis was tested using paleomagnetic data (24 sites and 192 cores) that indicated large counterclockwise vertical-axis rotations (70.9°, ± 6.7°), and moderate clockwise rotations (between 40° ± 4.1° and 56.2° ± 11.1) on either side of an east-west trending fault at the apex of the Isthmus (Rio Gatun Fault), consistent with Isthmus curvature. Sampling for paleomagnetism was performed on Cretaceous basaltic rocks of the Panama arc, some of them probably correlative to the Caribbean large igneous province. Also, sampling took place in younger Cenozoic cover rocks, as well as in the younger arc rocks. This database is here complemented with 15 new pilot paleomagnetic sites taken in eastern, central, and western Panama, and 3 new sites from Miocene cover rocks of what is now considered to be the southeastern-most tip of the Central American arc. The latter record clockwise vertical-axis rotations between 12 and 40°, in agreement with oroclinal bending hypothesis for the formation of the Isthmus of Panama. These new results begin to fill a gap in the paleomagnetic vertical-axis rotation database for the Panama arc. These results also support the continuity of the Central America arc to the east, into what is now docked to western South America.

  9. An Intact Dorsomedial Posterior Arcuate Nucleus is Not Necessary for Photoperiodic Responses in Siberian Hamsters1

    PubMed Central

    Teubner, Brett J.W.; Leitner, Claudia; Thomas, Michael A.; Ryu, Vitaly; Bartness, Timothy J.

    2015-01-01

    Seasonal responses of many animal species are triggered by changes in daylength and its transduction into a neuroendocrine signal by the pineal gland through the nocturnal duration of melatonin (MEL) release. The precise central sites necessary to receive, transduce, and relay the short day (SD) fall-winter MEL signals into seasonal responses and changes in physiology and behavior are unclear. In Siberian hamsters, SDs trigger decreases in body and lipid mass, testicular regression and pelage color changes. Several candidate genes and their central sites of expression have been proposed as components of the MEL transduction system with considerable recent focus on the arcuate nucleus (ARC) and its component, the dorsomedial posterior arcuate nucleus (dmpARC). This site has been postulated as a critical relay of SD information through the modulation of a variety of neurochemicals/receptors important for the control of energy balance. Here the necessity of an intact dmpARC for SD responses was tested by making electrolytic lesions of the Siberian hamster dmpARC and then exposing them to either long days (LD) or SDs for 12 weeks. The SD typical decreases in body and fat mass, food intake, testicular volume, serum testosterone concentrations, pelage color change and increased UCP-1 protein expression (a proxy for brown adipose tissue thermogenesis) all occurred despite the lack of an intact dmpARC. Although the Siberian hamster dmpARC contains photoperiod-modulated constituents, these data demonstrate that an intact dmpARC is not necessary for SD responses and not integral to the seasonal energy- and reproductive-related responses measured here. PMID:25647158

  10. Arc Inception Mechanism on a Solar Array Immersed in a Low-Density Plasma

    NASA Technical Reports Server (NTRS)

    Vayner, B.; Galofaro, J.; Ferguson, D.

    2001-01-01

    In this report, results are presented of an experimental and theoretical study of arc phenomena and snapover for two samples of solar arrays immersed in argon plasma. The effects of arcing and snapover are investigated. I-V curves are measured, and arc and snapover inception voltages and arc rates are determined within the wide range of plasma parameters. A considerable increase in arc rate due to absorption of molecules from atmospheric air has been confirmed. It is shown that increasing gas pressure causes increasing ion current collection and, consequently, arc rate even though the effect of conditioning also takes place. Arc sites have been determined by employing a video-camera. It is confirmed that keeping sample under high vacuum for a long time results in shifting arc threshold voltage well below -300 V. The results obtained seem to be important for the understanding of arc inception mechanism.

  11. The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility.

    PubMed

    Wall, Mark J; Collins, Dawn R; Chery, Samantha L; Allen, Zachary D; Pastuzyn, Elissa D; George, Arlene J; Nikolova, Viktoriya D; Moy, Sheryl S; Philpot, Benjamin D; Shepherd, Jason D; Müller, Jürgen; Ehlers, Michael D; Mabb, Angela M; Corrêa, Sonia A L

    2018-06-27

    Neuronal activity regulates the transcription and translation of the immediate-early gene Arc/Arg3.1, a key mediator of synaptic plasticity. Proteasome-dependent degradation of Arc tightly limits its temporal expression, yet the significance of this regulation remains unknown. We disrupted the temporal control of Arc degradation by creating an Arc knockin mouse (ArcKR) where the predominant Arc ubiquitination sites were mutated. ArcKR mice had intact spatial learning but showed specific deficits in selecting an optimal strategy during reversal learning. This cognitive inflexibility was coupled to changes in Arc mRNA and protein expression resulting in a reduced threshold to induce mGluR-LTD and enhanced mGluR-LTD amplitude. These findings show that the abnormal persistence of Arc protein limits the dynamic range of Arc signaling pathways specifically during reversal learning. Our work illuminates how the precise temporal control of activity-dependent molecules, such as Arc, regulates synaptic plasticity and is crucial for cognition. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  12. EPA True NO2 ground site measurements ?? multiple sites, TCEQ ground site measurements of meteorological and air pollution parameters ?? multiple sites ,GeoTASO NO2 Vertical Column

    EPA Pesticide Factsheets

    EPA True NO2 ground site measurements ?? multiple sites - http://www-air.larc.nasa.gov/cgi-bin/ArcView/discover-aq.tx-2013; TCEQ ground site measurements of meteorological and air pollution parameters ?? multiple sites - http://www-air.larc.nasa.gov/cgi-bin/ArcView/discover-aq.tx-2013; GeoTASO NO2 Vertical Column - http://www-air.larc.nasa.gov/cgi-bin/ArcView/discover-aq.tx-2013?FALCON=1This dataset is associated with the following publication:Nowlan, C., X. Lu, J. Leitch, K. Chance, G. González Abad, C. Lu, P. Zoogman, J. Cole, T. Delker, W. Good, F. Murcray, L. Ruppert, D. Soo, M. Follette-Cook, S. Janz, M. Kowalewski, C. Loughner, K. Pickering, J. Herman, M. Beaver, R. Long, J. Szykman, L. Judd, P. Kelley, W. Luke, X. Ren, and J. Al-Saadi. Nitrogen dioxide observations from the Geostationary Trace gas and Aerosol Sensor Optimization (GeoTASO) airborne instrument: Retrieval algorithm and measurements during DISCOVER-AQ Texas 2013. Atmospheric Measurement Techniques. Copernicus Publications, Katlenburg-Lindau, GERMANY, 9(6): 2647-2668, (2016).

  13. Quality assurance of road roughness measurement.

    DOT National Transportation Integrated Search

    2000-01-01

    This report describes a study designed to establish the accuracy and repeatability of high-speed, road-profiling equipment. This effort focused on a series of roughness validation sites. The study addresses selecting the appropriate sites, determinin...

  14. Constraining Sources of Subducted and Recycled Carbon Along the Sunda Arc

    NASA Astrophysics Data System (ADS)

    House, B. M.; Bebout, G. E.; Hilton, D. R.; Rodriguez, B.; Plank, T. A.

    2014-12-01

    From sediment subduction rates and C contents at ODP/DSDP sites 765 and 211, we estimate the rate of C subduction along ~2000 km of the East Sunda Arc to be ~0.4 Tg C yr-1, representing a significant source of subducted volatiles [1]. However volatile recycling efficiency and the provenance of recycled volatiles in this region remain poorly understood. With new δ13C measurements of both carbonate and organic carbon from sites 211 and 765, we present the most detailed study yet of the spatial variability of subducted C and recycled CO2 provenance along the strike of the arc. Furthermore we demonstrate the importance of oceanic crustal carbonate as a C source in a subduction zone that is otherwise carbonate starved. Carbonate content throughout the sediment column decreases dramatically between site 765, approximately 250 km from the Australian continental margin, and site 211, approximately 300 km southwest of the trench and outboard of the Sunda Strait between Sumatra and Java. Continental and shelf carbonate input from the Australian margin dominates shallow deposits at site 765, but underlying pelagic sediments are thought to contribute the majority of inorganic C to the arc. The paucity of carbonate in sediments at site 211 suggests that along this segment essentially all carbonate subducted is derived from altered ocean crust, presenting an opportunity to study the effects of crustal carbonate input. While previous C provenance studies relied on globally-averaged δ13C values for organic and inorganic C in subducted sediments, we present new estimates based on measured δ13CVPDB of carbonate (average of ~2‰ in subducted sediments) and organic carbon (-22.5 to -23‰ average) along with previously published efflux data [2]. These estimates suggest that the arc-averaged ratio of carbonate to organic C subducted along the East Sunda Arc is nearly identical to the inorganic to organic C ratio represented in volcanic and hydrothermal CO2 output, suggesting that differential devolatilization of carbonate and organic C is limited. Our calculated CO2 recycling efficiency of 10 to 20% - which does not include fore-arc outgassing - agrees with geochemical models predicting up to 80% of subducted C may be carried into the deep mantle [3]. [1] Hilton et al., 2002; [2] Halldórsson et al., 2013; [3] Cook-Kollars et al., 2014

  15. Nonlinear identification of the total baroreflex arc.

    PubMed

    Moslehpour, Mohsen; Kawada, Toru; Sunagawa, Kenji; Sugimachi, Masaru; Mukkamala, Ramakrishna

    2015-12-15

    The total baroreflex arc [the open-loop system relating carotid sinus pressure (CSP) to arterial pressure (AP)] is known to exhibit nonlinear behaviors. However, few studies have quantitatively characterized its nonlinear dynamics. The aim of this study was to develop a nonlinear model of the sympathetically mediated total arc without assuming any model form. Normal rats were studied under anesthesia. The vagal and aortic depressor nerves were sectioned, the carotid sinus regions were isolated and attached to a servo-controlled piston pump, and the AP and sympathetic nerve activity (SNA) were measured. CSP was perturbed using a Gaussian white noise signal. A second-order Volterra model was developed by applying nonparametric identification to the measurements. The second-order kernel was mainly diagonal, but the diagonal differed in shape from the first-order kernel. Hence, a reduced second-order model was similarly developed comprising a linear dynamic system in parallel with a squaring system in cascade with a slower linear dynamic system. This "Uryson" model predicted AP changes 12% better (P < 0.01) than a linear model in response to new Gaussian white noise CSP. The model also predicted nonlinear behaviors, including thresholding and mean responses to CSP changes about the mean. Models of the neural arc (the system relating CSP to SNA) and peripheral arc (the system relating SNA to AP) were likewise developed and tested. However, these models of subsystems of the total arc showed approximately linear behaviors. In conclusion, the validated nonlinear model of the total arc revealed that the system takes on an Uryson structure. Copyright © 2015 the American Physiological Society.

  16. Nonlinear identification of the total baroreflex arc

    PubMed Central

    Moslehpour, Mohsen; Kawada, Toru; Sunagawa, Kenji; Sugimachi, Masaru

    2015-01-01

    The total baroreflex arc [the open-loop system relating carotid sinus pressure (CSP) to arterial pressure (AP)] is known to exhibit nonlinear behaviors. However, few studies have quantitatively characterized its nonlinear dynamics. The aim of this study was to develop a nonlinear model of the sympathetically mediated total arc without assuming any model form. Normal rats were studied under anesthesia. The vagal and aortic depressor nerves were sectioned, the carotid sinus regions were isolated and attached to a servo-controlled piston pump, and the AP and sympathetic nerve activity (SNA) were measured. CSP was perturbed using a Gaussian white noise signal. A second-order Volterra model was developed by applying nonparametric identification to the measurements. The second-order kernel was mainly diagonal, but the diagonal differed in shape from the first-order kernel. Hence, a reduced second-order model was similarly developed comprising a linear dynamic system in parallel with a squaring system in cascade with a slower linear dynamic system. This “Uryson” model predicted AP changes 12% better (P < 0.01) than a linear model in response to new Gaussian white noise CSP. The model also predicted nonlinear behaviors, including thresholding and mean responses to CSP changes about the mean. Models of the neural arc (the system relating CSP to SNA) and peripheral arc (the system relating SNA to AP) were likewise developed and tested. However, these models of subsystems of the total arc showed approximately linear behaviors. In conclusion, the validated nonlinear model of the total arc revealed that the system takes on an Uryson structure. PMID:26354845

  17. Origin of ophiolite complexes related to intra-oceanic subduction initiation: implications of IODP Expedition 352 (Izu-Bonin fore arc)

    NASA Astrophysics Data System (ADS)

    Robertson, Alastair; Avery, Aaron; Carvallo, Claire; Christeson, Gail; Ferré, Eric; Kurz, Walter; Kutterolf, Steffen; Morgan, Sally; Pearce, Julian; Reagan, Mark; Sager, William; Shervais, John; Whattam, Scott; International Ocean Discovery Program Expedition 352 (Izu-Bonin-Mariana Fore Arc), the Scientific Party of

    2015-04-01

    Ophiolites, representing oceanic crust exposed on land (by whatever means), are central to the interpretation of many orogenic belts (e.g. E Mediterranean). Based mostly on geochemical evidence, ophiolites are widely interpreted, in many but by no means all cases, as having formed within intra-oceanic settings above subduction zones (e.g. Troodos ophiolite, Cyprus). Following land geological, dredging and submersible studies, fore arcs of the SW Pacific region became recognised as likely settings of supra-subduction zone ophiolite genesis. This hypothesis was tested by recent drilling of the Izu-Bonin fore arc. Four sites were drilled, two on the outer fore arc and two on the upper trench slope. Site survey seismic data, combined with borehole data, indicate that three of the sites are located in fault-controlled sediment ponds that formed in response to dominantly down-to the-west extensional faulting (with hints of preceding top-to-the-east compressional thrusting). The sediments overlying the igneous basement, of maximum Late Eocene to Recent age, document ash and aeolian input, together with mass wasting of the fault-bounded sediment ponds. At the two more trenchward sites (U1440 and U1441), mostly tholeiitic basalts were drilled, including massive and pillowed lavas and hyaloclastite. Geochemically, these extrusives are of near mid-oceanic ridge basalt composition (fore arc basalts). Subtle chemical deviation from normal MORB can be explained by weakly fluid-influenced melting during decompression melting in the earliest stages of supra-subduction zone spreading (not as 'trapped' older MORB). The remaining two sites, c. 6 km to the west (U1439 and U1442), penetrated dominantly high-magnesian andesites, known as boninites, largely as fragmental material. Their formation implies the extraction of highly depleted magmas from previously depleted, refractory upper mantle in a supra-subduction zone setting. Following supra-subduction zone spreading, the active modern arc formed c. 200 km westwards of the trench. The new drilling evidence proves that both fore arc-type basalt and boninite formed in a fore arc setting soon after subduction initiation (c.52 Ma). Comparisons with ophiolites reveal many similarities, especially the presence of fore arc-type basalts and low calcium boninites. The relative positions of the fore arc basalts, boninites and arc basalts in the Izu Bonin and Mariana forearc (based on previous studies) can be compared with the positions of comparable units in a range of ophiolite complexes in orogenic belts including the Troodos, Oman, Greek (e.g. Vourinos), Albanian (Mirdita), Coast Range (California) and Bay of Islands (Newfoundland) ophiolites. The comparisons support the interpretation that all of the ophiolites formed during intra-oceanic subduction initiation. There are also some specific differences between the individual ophiolites suggesting that ophiolites should be interpreted individually in their regional tectonic settings.

  18. Soil Physical, Chemical, and Thermal Characterization, Teller Road Site, Seward Peninsula, Alaska, 2016

    DOE Data Explorer

    Graham, David; Kholodov, Alexander; Wilson, Cathy; Moon, Ji-Won; Romanovsky, Vladimir; Busey, Bob

    2018-02-05

    This dataset provides the results of physical, chemical, and thermal characterization of soils at the Teller Road Site, Seward Peninsula, Alaska. Soil pits were dug from 7-14 September 2016 at designated Intensive Stations 2 through 9 at the Teller Road MM 27 Site. This dataset includes field observations and descriptions of soil layers or horizons, field measurements of soil volumetric water content, soil temperature, thermal conductivity, and heat capacity. Laboratory measurements of soil properties include gravimetric water content, bulk density, volumetric water content, and total carbon and nitrogen.

  19. Arcjet power supply and start circuit

    NASA Technical Reports Server (NTRS)

    Gruber, Robert P. (Inventor)

    1988-01-01

    A dc power supply for spacecraft arcjet thrusters has an integral automatic starting circuit and an output averaging inductor. The output averaging inductor, in series with the load, provides instantaneous current control, and ignition pulse and an isolated signal proportional to the arc voltage. A pulse width modulated converter, close loop configured, is also incorporated to give fast response output current control.

  20. A Three-Body Resonance Confines the Ring-Arcs of Neptune

    NASA Astrophysics Data System (ADS)

    Showalter, Mark; Lissauer, Jack J.; de Pater, Imke; French, Robert S.

    2017-10-01

    Two prominent arcs in Neptune's Adams ring have persisted for more than thirty years. Absent active confinement, the arcs would have dissipated in a few years due to Kepler shear. Based on nearly 30 years of astrometry from Voyager and the Hubble Space Telescope, we now find that the orbital semimajor axis of the arcs falls within ~ 10 meters of a strong three-body mean motion resonance, which involves the two nearest moons, Galatea and Larissa. Resonances of comparable strength are typically spaced by several km in the vicinity of the ring, making this particular association unlikely to be a coincidence. Furthermore, each arc falls within the longitudinal boundaries of one of the 39 corotation sites that this resonance creates. Collisionless numerical simulations confirm that the resonance is capable of confining ring material within these corotation sites; more realistic, collisional simulations are in progress. The dynamics appears to be generally similar to that from an earlier model in which the arcs were confined by a two-body resonance with Galatea (Porco, Science 253, 995-1001, 1991). However, subsequent observations have shown that the arcs' mean motion is definitively outside the resonance as originally proposed. Subsequent models have invoked one or more embedded moonlets to confine the arcs, but this new model eliminates the need to invoke additional unseen moonlets. We hypothesize that the arcs comprise debris ejected from an impact into the Adams ring multiple decades ago. Only a fraction of that debris landed precisely in the resonance. The additional arcs imaged by Voyager in 1990 comprise material that orbited close to, but not in, the resonance; that material has dispersed slowly over the subsequent decades, leaving only two arcs that persist to this day.

  1. Effects of road decommissioning on carbon stocks, losses, and emissions in north coastal California

    USGS Publications Warehouse

    Madej, Mary Ann; Seney, Joseph; van Mantgem, Philip

    2013-01-01

    During the last 3 decades, many road removal projects have been implemented on public and private lands in the United States to reduce erosion and other impacts from abandoned or unmaintained forest roads. Although effective in decreasing sediment production from roads, such activities have a carbon (C) cost as well as representing a carbon savings for an ecosystem. We assessed the carbon budget implications of 30 years of road decommissioning in Redwood National Park in north coastal California. Road restoration techniques, which evolved during the program, were associated with various carbon costs and savings. Treatment of 425 km of logging roads from 1979 to 2009 saved 72,000 megagrams (Mg) C through on-site soil erosion prevention, revegetation, and soil development on formerly compacted roads. Carbon sequestration will increase in time as forests and soils develop more fully on the restored sites. The carbon cost for this road decommissioning work, based on heavy equipment and vehicle fuel emissions, short-term soil loss, and clearing of vegetation, was 23,000 Mg C, resulting in a net carbon savings of 49,000 Mg C to date. Nevertheless, the degree to which soil loss is a carbon sink or source in steep mountainous watersheds needs to be further examined. The ratio of carbon costs to savings will differ by ecosystem and road removal methodology, but the procedure outlined here to assess carbon budgets on restoration sites should be transferable to other systems.

  2. 75 FR 17126 - Foreign-Trade Zone 26-Atlanta, Georgia, Application for Expansion and Reorganization under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ..., Jeffersonville (Twiggs County); Site 16 (308 acres) -- Meridian 75 Logistics Center, located at Interstate 75 and Rumble Road, Forsyth (Monroe County); Site 17 (193 acres) -- Majestic Airport Center III, located at... Futral Road, Griffin (Spalding County); Site 9 (321 acres) -- at the Hamilton Mill Business Center...

  3. The effects of peer influence on adolescent pedestrian road-crossing decisions.

    PubMed

    Pfeffer, K; Hunter, E

    2013-01-01

    Adolescence is a high-risk period for pedestrian injury. It is also a time of heightened susceptibility to peer influence. The aim of this research was to examine the effects of peer influence on the pedestrian road-crossing decisions of adolescents. Using 10 videos of road-crossing sites, 80 16- to 18-year-olds were asked to make pedestrian road-crossing decisions. Participants were assigned to one of 4 experimental conditions: negative peer (influencing unsafe decisions), positive peer (influencing cautious decisions), silent peer (who observed but did not comment), and no peer (the participant completed the task alone). Peers from the adolescent's own friendship group were recruited to influence either an unsafe or a cautious decision. Statistically significant differences were found between peer conditions. Participants least often identified safe road-crossing sites when accompanied by a negative peer and more frequently identified dangerous road-crossing sites when accompanied by a positive peer. Both cautious and unsafe comments from a peer influenced adolescent pedestrians' decisions. These findings showed that road-crossing decisions of adolescents were influenced by both unsafe and cautious comments from their peers. The discussion highlighted the role that peers can play in both increasing and reducing adolescent risk-taking.

  4. A laboratory facility for electric vehicle propulsion system testing

    NASA Technical Reports Server (NTRS)

    Sargent, N. B.

    1980-01-01

    The road load simulator facility located at the NASA Lewis Research Center enables a propulsion system or any of its components to be evaluated under a realistic vehicle inertia and road loads. The load is applied to the system under test according to the road load equation: F(net)=K1F1+K2F2V+K3 sq V+K4(dv/dt)+K5 sin theta. The coefficient of each term in the equation can be varied over a wide range with vehicle inertial representative of vehicles up to 7500 pounds simulated by means of flywheels. The required torque is applied by the flywheels, a hydroviscous absorber and clutch, and a drive motor integrated by a closed loop control system to produce a smooth, continuous load up to 150 horsepower.

  5. 5. VIEW OF THE LOCATION FOR A PROPOSED SPUR ROAD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. VIEW OF THE LOCATION FOR A PROPOSED SPUR ROAD FROM KINGS CANYON ROAD TO THE PROPOSED HELICOPTER LANDING SITE #11. LOCATED AT MILEPOST 0.55, FACING NORTH 53ø EAST (53 ). - Kings Canyon Road, Carson City, Carson City, NV

  6. Comparative source apportionment of PM10 in Switzerland for 2008/2009 and 1998/1999 by Positive Matrix Factorisation

    NASA Astrophysics Data System (ADS)

    Gianini, M. F. D.; Fischer, A.; Gehrig, R.; Ulrich, A.; Wichser, A.; Piot, C.; Besombes, J.-L.; Hueglin, C.

    2012-07-01

    PM10 speciation data from various sites in Switzerland for two time periods (January 1998-March 1999 and August 2008-July 2009) have been analysed for major sources by receptor modelling using Positive Matrix Factorisation (PMF). For the 2008/2009 period, it was found that secondary aerosols (sulphate- and nitrate-rich secondary aerosols, SSA and NSA) are the most abundant components of PM10 at sites north of the Alps. Road traffic and wood combustion were found to be the largest sources of PM10 at these sites. Except at the urban roadside site where road traffic is dominating (40% of PM10 -- including road salt), the annual average contribution of these two sources is of similar importance (17% and 14% of PM10, respectively). At a rural site south of the Alps wood combustion and road traffic contributions to PM10 were higher (31% and 24%, respectively), and the fraction of secondary aerosols lower (29%) than at similar site types north of the Alps. Comparison of PMF analyses for the two time periods (1998/1999 and 2008/2009) revealed decreasing average contributions of road traffic and SSA to PM10 at all sites. This indicates that the measures that were implemented in Switzerland and in neighbouring countries to reduce emissions of sulphur dioxide and PM10 from road traffic were successful. On the other hand, contributions of wood combustion did not change during this ten year period, and the contribution of nitrate-rich secondary aerosols has even increased. It is shown that PMF can be a helpful tool for the assessment of long-term changes of source contributions to ambient particulate matter.

  7. 75 FR 53637 - Foreign-Trade Zone 104-Savannah, GA; Application for Reorganization Under Alternative Site Framework

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... Site 10 (62.9 acres)--Savannah Logistics Park at Morgan Center, S.H. Morgan Parkway and Pooler Parkway...)--SPA Industrial Park, East of the I-95/U.S. 80 Interchange, Chatham County; Site 5 (24.0)--Savannah... Industrial Park, 380 Sunbury Road, Midway; Site 8 (98.0 acres)--Tremont Road near I-16 and Georgia 516...

  8. The development of shock wave overpressure driven by channel expansion of high current impulse discharge arc

    NASA Astrophysics Data System (ADS)

    Xiong, Jia-ming; Li, Lee; Dai, Hong-yu; Wu, Hai-bo; Peng, Ming-yang; Lin, Fu-chang

    2018-03-01

    During the formation of a high current impulse discharge arc, objects near the discharge arc will be strongly impacted. In this paper, a high power, high current gas switch is used as the site of the impulse discharge arc. The explosion wave theory and the arc channel energy balance equation are introduced to analyze the development of the shock wave overpressure driven by the high current impulse discharge arc, and the demarcation point of the arc channel is given, from which the energy of the arc channel is no longer converted into shock waves. Through the analysis and calculation, it is found that the magnitude of the shock wave overpressure caused by impulse discharge arc expansion is closely related to the arc current rising rate. The arc shock wave overpressure will undergo a slow decay process and then decay rapidly. The study of this paper will perform the function of deepening the understanding of the physical nature of the impulse arc discharge, which can be used to explain the damage effect of the high current impulse discharge arc.

  9. Urban snow indicates pollution originating from road traffic.

    PubMed

    Kuoppamäki, Kirsi; Setälä, Heikki; Rantalainen, Anna-Lea; Kotze, D Johan

    2014-12-01

    Traffic is a major source of pollutants in cities. In this well-replicated study we analysed a broad array of contaminants in snowpacks along roads of different traffic intensities. The majority of pollutants showed a similar pattern with respect to traffic intensity: pH and conductivity as well as concentrations of PAHs, total suspended solids, phosphorus and most heavy metals were higher next to high intensity roads compared to low intensity roads. These pollutant levels also decreased considerably up to 5 m distance from the roads. Furthermore, apart from nitrogen, these variables increased in concentration from control sites in urban forest patches to road bank sites next to roads of low, intermediate and high traffic intensities. The deposition pattern of various traffic-derived pollutants--whether gaseous or particle-bound--was the same. Such information can be useful for the purposes of managing pollutants in urban areas. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Mass Balance, Beneficial Use Products, and Cost Comparisons of Four Sediment Treatment Technologies Near Commercialization

    DTIC Science & Technology

    2011-03-01

    Superfund Innovative Technology Evaluation Program (SITE) • Assessment and Remediation of Contaminated Sediment Program (ARCS) • Contaminated Sediment...Agency (USEPA). 1994. Assessment and Remediation of Contaminated Sediments (ARCS) Program Remediation Guidance Document. EPA/905/R-94/003. Chicago, IL...conducted under one of the four following programs: • Superfund Innovative Technology Evaluation (SITE) Program • Assessment and Remediation of

  11. 27 CFR 9.55 - Bell Mountain.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... following boundary description is the summit of Bell Mountain (1,956 feet). (2) Boundary Description. (i) From the starting point, the boundary proceeds due southward for exactly one half mile; (ii) Then..., where marked with an elevation of 1,773 feet; (iii) Then generally southward along Willow City Loop Road...

  12. 27 CFR 9.55 - Bell Mountain.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... following boundary description is the summit of Bell Mountain (1,956 feet). (2) Boundary Description. (i) From the starting point, the boundary proceeds due southward for exactly one half mile; (ii) Then..., where marked with an elevation of 1,773 feet; (iii) Then generally southward along Willow City Loop Road...

  13. 27 CFR 9.55 - Bell Mountain.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... following boundary description is the summit of Bell Mountain (1,956 feet). (2) Boundary Description. (i) From the starting point, the boundary proceeds due southward for exactly one half mile; (ii) Then..., where marked with an elevation of 1,773 feet; (iii) Then generally southward along Willow City Loop Road...

  14. 27 CFR 9.55 - Bell Mountain.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... following boundary description is the summit of Bell Mountain (1,956 feet). (2) Boundary Description. (i) From the starting point, the boundary proceeds due southward for exactly one half mile; (ii) Then..., where marked with an elevation of 1,773 feet; (iii) Then generally southward along Willow City Loop Road...

  15. Here We Go Round the M25

    ERIC Educational Resources Information Center

    McCartney, Mark; Walsh, Ian

    2006-01-01

    A simple model for how traffic moves around a closed loop of road is introduced. The consequent analysis of the model can be used as an application of techniques taught at first year undergraduate level, and as a motivator to encourage students to think critically about model formulation and interpretation.

  16. Dust emissions from unpaved roads on the Colorado Plateau

    NASA Astrophysics Data System (ADS)

    Duniway, M.; Flagg, C.; Belnap, J.

    2013-12-01

    On the Colorado Plateau, elevated levels of aeolian dust have become a major land management and policy concern due to its influence on climate, weather, terrestrial ecosystem dynamics, landscape development and fertility, melting of snow and ice, air quality, and human health. Most desert soil surfaces are stabilized by plants, rocks, and/or physical or biological soil crusts, but once disturbed, sediment production from these surfaces can increase dramatically. Road development and use is a common surface disturbing activity in the region. The extent and density of roads and road networks is rapidly increasing due to continued energy exploration, infrastructure development, and off-highway recreation activities. Though it is well known that unpaved roads produce dust, the relative contribution of dust from existing roads or the implications of future road development to regional dust loading is unknown. To address this need, we have initiated a multifaceted research effort to evaluating dust emissions from unpaved roads regionally. At 34 sites arranged across various road surfaces and soil textures in southeastern Utah, we are: 1) monitoring dust emissions, local wind conditions, and vehicle traffic and 2) evaluating fugitive dust potential using a portable wind tunnel and measuring road characteristics that affect dust production. We will then 3) develop a GIS-based model that integrates results from 1 & 2 to estimate potential dust contributions from current and future scenarios of regional road development. Passive, horizontal sediment traps were installed at three distances downwind from the road edge. One control trap was placed upwind of the samplers to account for local, non-road dust emissions. An electronic vehicle counter and anemometer were also installed at monitoring sites. Dust samples were collected every three months at fixed heights, 15 cm up to 100 cm above the soil surface, from March 2010 to the present. Threshold friction velocities (TFV), the minimum wind velocity required to initiate erosion, and sediment production were also quantified using a portable wind tunnel at monitoring sites. Additionally, numerous characteristics including gravel cover, particle-size distribution, soil compaction, and loose-erodible material were measured on road surfaces at monitoring sites. Preliminary results suggest that roads are an important regional dust source, as emissions from roads are comparable to non-road, rural sources that are being monitored concurrently. While gravel roads produce more dust per day on average, per vehicle emissions are larger on dirt roads. Dust flux decreases with distance from the road edge on all road types, however this decline is less pronounced on dirt roads. Portable wind tunnel results indicate that TFV is consistently lower on dirt versus gravel roads across all soil types. Fugitive dust flux is generally larger and more variable on dirt roads compared to gravel roads. Initial analyses suggest that several easily measurable road surface characteristics can potentially be used to predict both TFV and sediment production, including: total gravel cover, gravel particle-size classes, clay content, and road compaction. The relation between TFV and total gravel cover in particular appears to be non-linear, with TFV increasing rapidly above ~40% gravel cover.

  17. Identification and characterization of the sodium-binding site of activated protein C.

    PubMed

    He, X; Rezaie, A R

    1999-02-19

    Activated protein C (APC) requires both Ca2+ and Na+ for its optimal catalytic function. In contrast to the Ca2+-binding sites, the Na+-binding site(s) of APC has not been identified. Based on a recent study with thrombin, the 221-225 loop is predicted to be a potential Na+-binding site in APC. The sequence of this loop is not conserved in trypsin. We engineered a Gla domainless form of protein C (GDPC) in which the 221-225 loop was replaced with the corresponding loop of trypsin. We found that activated GDPC (aGDPC) required Na+ (or other alkali cations) for its amidolytic activity with dissociation constant (Kd(app)) = 44.1 +/- 8.6 mM. In the presence of Ca2+, however, the requirement for Na+ by aGDPC was eliminated, and Na+ stimulated the cleavage rate 5-6-fold with Kd(app) = 2.3 +/- 0.3 mM. Both cations were required for efficient factor Va inactivation by aGDPC. In the presence of Ca2+, the catalytic function of the mutant was independent of Na+. Unlike aGDPC, the mutant did not discriminate among monovalent cations. We conclude that the 221-225 loop is a Na+-binding site in APC and that an allosteric link between the Na+ and Ca2+ binding loops modulates the structure and function of this anticoagulant enzyme.

  18. 6. View from heat sink (south to north), west oblique ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. View from heat sink (south to north), west oblique of missile site control building - Stanley R. Mickelsen Safeguard Complex, Missile Site Control Building, Northeast of Tactical Road; southeast of Tactical Road South, Nekoma, Cavalier County, ND

  19. Travel Information, Transportation & Public Facilities, State of Alaska

    Science.gov Websites

    outside site Report Potholes Road Conditions (511) Road Maintenance Central Region Maintenance & ; Operations Northern Region Maintenance & Operations Southcoast Region Maintenance & Operations Road Weather Information System Street Sweeping - Anchorage & Eagle River Winter Road Maintenance Priority

  20. 76 FR 23286 - New Pneumatic Off-the-Road Tires From the People's Republic of China: Final Results of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-26

    ... sites. They can also be used to perform ``rough grading'' in road construction. \\10\\ A straddle carrier... commonly used in maintenance of unpaved roads and road construction to prepare the base course onto which... DEPARTMENT OF COMMERCE International Trade Administration [C-570-913] New Pneumatic Off-the-Road...

  1. 75 FR 34098 - Certain New Pneumatic Off-the-Road Tires from the People's Republic of China: Initiation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ..., etc., typically around construction sites. They can also be used to perform ``rough grading'' in road... grading.'' Graders are commonly used in maintenance of unpaved roads and road construction to prepare the...-the-Road Tires from the People's Republic of China: Initiation of Changed Circumstances Review AGENCY...

  2. The Effect of Arc Proximity on Hydrothermal Activity Along Spreading Centers: New Evidence From the Mariana Back Arc (12.7°N-18.3°N)

    NASA Astrophysics Data System (ADS)

    Baker, Edward T.; Walker, Sharon L.; Resing, Joseph A.; Chadwick, William W.; Merle, Susan G.; Anderson, Melissa O.; Butterfield, David A.; Buck, Nathan J.; Michael, Susanna

    2017-11-01

    Back-arc spreading centers (BASCs) form a distinct class of ocean spreading ridges distinguished by steep along-axis gradients in spreading rate and by additional magma supplied through subduction. These characteristics can affect the population and distribution of hydrothermal activity on BASCs compared to mid-ocean ridges (MORs). To investigate this hypothesis, we comprehensively explored 600 km of the southern half of the Mariana BASC. We used water column mapping and seafloor imaging to identify 19 active vent sites, an increase of 13 over the current listing in the InterRidge Database (IRDB), on the bathymetric highs of 7 of the 11 segments. We identified both high and low (i.e., characterized by a weak or negligible particle plume) temperature discharge occurring on segment types spanning dominantly magmatic to dominantly tectonic. Active sites are concentrated on the two southernmost segments, where distance to the adjacent arc is shortest (<40 km), spreading rate is highest (>48 mm/yr), and tectonic extension is pervasive. Re-examination of hydrothermal data from other BASCs supports the generalization that hydrothermal site density increases on segments <90 km from an adjacent arc. Although exploration quality varies greatly among BASCs, present data suggest that, for a given spreading rate, the mean spatial density of hydrothermal activity varies little between MORs and BASCs. The present global database, however, may be misleading. On both BASCs and MORs, the spatial density of hydrothermal sites mapped by high-quality water-column surveys is 2-7 times greater than predicted by the existing IRDB trend of site density versus spreading rate.

  3. The chloroplast min system functions differentially in two specific nongreen plastids in Arabidopsis thaliana.

    PubMed

    Wang, Peng; Zhang, Jie; Su, Jianbin; Wang, Peng; Liu, Jun; Liu, Bing; Feng, Dongru; Wang, Jinfa; Wang, Hongbin

    2013-01-01

    The nongreen plastids, such as etioplasts, chromoplasts, etc., as well as chloroplasts, are all derived from proplastids in the meristem. To date, the Min system members in plants have been identified as regulators of FtsZ-ring placement, which are essential for the symmetrical division of chloroplasts. However, the regulation of FtsZ-ring placement in nongreen plastids is poorly understood. In this study, we investigated the division site placement of nongreen plastids by examining the etioplasts as representative in Arabidopsis Min system mutants. Surprisingly, the shape and number of etioplasts in cotyledons of arc3, arc11 and mcd1 mutants were similar to that observed in wild-type plants, whereas arc12 and parc6 mutants exhibited enlarged etioplasts that were reduced in number. In order to examine nongreen plastids in true leaves, we silenced the ALB3 gene in these Min system mutant backgrounds to produce immature chloroplasts without the thylakoidal network using virus induced gene silencing (VIGS). Interestingly, consistent with our observations in etioplasts, enlarged and fewer nongreen plastids were only detected in leaves of parc6 (VIGS-ALB3) and arc12 (VIGS-ALB3) plants. Further, the FtsZ-ring assembled properly at the midpoint in nongreen plastids of arc3, arc11 and mcd1 (VIGS-ALB3) plants, but organized into multiple rings in parc6 (VIGS-ALB3) and presented fragmented filaments in arc12 (VIGS-ALB3) plants, suggesting that division site placement in nongreen plastids requires fewer components of the plant Min system. Taken together, these results suggest that division site placement in nongreen plastids is different from that in chloroplasts.

  4. The Chloroplast Min System Functions Differentially in Two Specific Nongreen Plastids in Arabidopsis thaliana

    PubMed Central

    Wang, Peng; Zhang, Jie; Su, Jianbin; Wang, Peng; Liu, Jun; Liu, Bing; Feng, Dongru; Wang, Jinfa; Wang, Hongbin

    2013-01-01

    The nongreen plastids, such as etioplasts, chromoplasts, etc., as well as chloroplasts, are all derived from proplastids in the meristem. To date, the Min system members in plants have been identified as regulators of FtsZ-ring placement, which are essential for the symmetrical division of chloroplasts. However, the regulation of FtsZ-ring placement in nongreen plastids is poorly understood. In this study, we investigated the division site placement of nongreen plastids by examining the etioplasts as representative in Arabidopsis Min system mutants. Surprisingly, the shape and number of etioplasts in cotyledons of arc3, arc11 and mcd1 mutants were similar to that observed in wild-type plants, whereas arc12 and parc6 mutants exhibited enlarged etioplasts that were reduced in number. In order to examine nongreen plastids in true leaves, we silenced the ALB3 gene in these Min system mutant backgrounds to produce immature chloroplasts without the thylakoidal network using virus induced gene silencing (VIGS). Interestingly, consistent with our observations in etioplasts, enlarged and fewer nongreen plastids were only detected in leaves of parc6 (VIGS-ALB3) and arc12 (VIGS-ALB3) plants. Further, the FtsZ-ring assembled properly at the midpoint in nongreen plastids of arc3, arc11 and mcd1 (VIGS-ALB3) plants, but organized into multiple rings in parc6 (VIGS-ALB3) and presented fragmented filaments in arc12 (VIGS-ALB3) plants, suggesting that division site placement in nongreen plastids requires fewer components of the plant Min system. Taken together, these results suggest that division site placement in nongreen plastids is different from that in chloroplasts. PMID:23936263

  5. Deletion of loop fragment adjacent to active site diminishes the stability and activity of exo-inulinase.

    PubMed

    Arjomand, Maryam Rezaei; Habibi-Rezaei, Mehran; Ahmadian, Gholamreza; Hassanzadeh, Malihe; Karkhane, Ali Asghar; Asadifar, Mandana; Amanlou, Massoud

    2016-11-01

    Inulinases are classified as hydrolases and widely used in the food and medical industries. Here, we report the deletion of a six-membered adjacent active site loop fragment ( 74 YGSDVT 79 sequence) from third Ω-loop of the exo-inulinase containing aspartate residue from Aspergillus niger to study its structural and functional importance. Site-directed mutagenesis was used to create the mutant of the exo-inulinase (Δ6SL). To investigate the stability of the region spanning this loop, MD simulations were performed 80ns for 20-85 residues. Molecular docking was performed to compare the interactions in the active sites of enzymes with fructose as a ligand. Accordingly, the functional thermostability of the exo-inulinase was significantly decreased upon loop fragment deletion. Evaluation of the kinetics parameters (V max , K m , k cat and, k cat /K m ) and activation energy (E a ) of the catalysis of enzymes indicated the importance of the deleted sequence on the catalytic performance of the enzyme. In conclusion, six-membered adjacent active site loop fragment not only plays a crucial role in the stability of the enzyme, but also it involves in the enzyme catalysis through lowering the activation energy of the catalysis and effective improving the catalytic performance. Copyright © 2016. Published by Elsevier B.V.

  6. Estimation and control of droplet size and frequency in projected spray mode of a gas metal arc welding (GMAW) process.

    PubMed

    Anzehaee, Mohammad Mousavi; Haeri, Mohammad

    2011-07-01

    New estimators are designed based on the modified force balance model to estimate the detaching droplet size, detached droplet size, and mean value of droplet detachment frequency in a gas metal arc welding process. The proper droplet size for the process to be in the projected spray transfer mode is determined based on the modified force balance model and the designed estimators. Finally, the droplet size and the melting rate are controlled using two proportional-integral (PI) controllers to achieve high weld quality by retaining the transfer mode and generating appropriate signals as inputs of the weld geometry control loop. Copyright © 2011 ISA. Published by Elsevier Ltd. All rights reserved.

  7. Physical properties of fore-arc basalt and boninite in Izu-Bonin-Mariana forearc recovered by IODP Expedition 352

    NASA Astrophysics Data System (ADS)

    Honda, M.; Michibayashi, K.; Almeev, R. R.; Christeson, G. L.; Sakuyama, T.; Yamamoto, Y.; Watanabe, T.

    2016-12-01

    The Izu-Bonin-Mariana (IBM) arc is a typical intraoceanic arc system and is the type locality for subduction initiation. IODP-IBM project is aimed to understand subduction initiation, arc evolution, and continental crust formation. Expedition 352 is one of the IBM projects and that has drilled four sites at the IBM fore-arc. Expedition 352 has successfully recovered fore-arc basalts and boninites related to seafloor spreading during the subduction initiation as well as the earliest arc development. The fore-arc basalts were recovered from two sites (U1440 and U1441) at the deeper trench slope to the east, whereas the boninites were recovered from two sites (U1439 and U1442) at the shallower slope to the west. In this study, we studied textures and physical properties of both the fore-arc basalt and the boninite samples recovered by IODP Expedition 352. The fore-arc basalt samples showed aphyric texture, whereas the boninites showed hyaloclastic, aphyric and porphyritic textures. For the physical properties, we measured density, porosity, P-wave velocity and anisotropy of magnetic susceptibility. P-wave velocities were measured under ordinary and confining pressure. As a result, the densities are in a range between 2 g/cm3 and 3 g/cm3. The porosities are in a range between 5 % and 40 %. The P-wave velocities are in a wide range from 3 km/s to 5.5 km/s and have a positive correlation to the densities. The magnetic susceptibilities showed bimodal distributions so that the physical properties were classified into two groups: a high magnetic susceptibility group (>5×10-3) and a low magnetic susceptibility group (<5×10-3). The high magnetic susceptibility group is almost identical with the fore-arc basalt and boninite samples with the higher correlation trend between the P-wave velocities and the densities, whereas the low magnetic susceptibility group is only the boninite samples with the lower correlation trend between the P-wave velocities and the densities. It suggests that the densities could be related to the occurrence of magnetite in the samples, since the magnetic susceptibilities were remarkably correlated with the relationships between P-wave velocities and densities. In addition, these trends have also been found in the physical properties measured on board during Expedition 351.

  8. The early history of the closed loop fiber optic gyro and derivative sensors at McDonnell Douglas, Blue Road Research and Columbia Gorge Research

    NASA Astrophysics Data System (ADS)

    Udd, Eric

    2016-05-01

    On September 29, 1977 the first written disclosure of a closed loop fiber optic gyro was witnessed and signed off by four people at McDonnell Douglas Astronautics Company in Huntington Beach, California. Over the next ten years a breadboard demonstration unit, and several prototypes were built. In 1987 the fundamental patent for closed loop operation began a McDonnell Douglas worldwide licensing process. Internal fiber optic efforts were redirected to derivative sensors and inventions. This included development of acoustic, strain and distributed sensors as well as a Sagnac interferometer based secure fiber optic communication system and the new field of fiber optic smart structures. This paper provides an overview of these activities and transitions.

  9. Development of High-power LED Lighting Luminaires Using Loop Heat Pipe

    NASA Astrophysics Data System (ADS)

    Huang, Bin-Juine; Huang, Huan-Hsiang; Chen, Chun-Wei; Wu, Min-Sheng

    High-power LED should reject about 6 times of heat of the conventional lighting device and keep the LED junction temperature below 80°C to assure reliability and low light decay. In addition, no fan is allowed and the heat dissipation design should not interfere with the industrial design of lighting fixture and have a light weight. This thus creates an extreme thermal management problem. The present study has shown that, using a special heat dissipation technology (loop heat pipe), the high-power LED lighting luminaire with input power from 36 to 150W for outdoor and indoor applications can be achieved with light weight, among 0.96 to 1.57 kg per 1,000 lumen of net luminous flux output from the luminaire. The loop heat pipe uses a flexible connecting pipe as the condenser which can be wounded around the reflector of the luminaire to dissipate the heat to the ambient air by natural convection. For roadway or street lighting application, the present study shows that a better optical design of LED lamps can further result in power consumption reduction, based on the same illumination on road surface. The high-power LED luminaries developed in the present study have shown that the energy saving is > 50% in road lighting applications as compared to sodium light or > 70% compared to mercury light.

  10. Identifying security checkpoints locations to protect the major U.S. urban areas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cuellar-Hengartner, Leticia; Watkins, Daniel; Kubicek, Deborah A.

    Transit networks are integral to the economy and to society, but at the same time they could allow terrorists to transport weapons of mass destruction into any city. Road networks are especially vulnerable, because they lack natural checkpoints unlike air networks that have security measures in place at all major airports. One approach to mitigate this risk is ensuring that every road route passes through at least one security checkpoint. Using the Ford-Fulkerson maximum-flow algorithm, we generate a minimum set of checkpoint locations within a ring-shaped buffer area surrounding the 50 largest US urban areas. We study how the numbermore » of checkpoints changes as we increase the buffer width to perform a cost-benefit analysis and to identify groups of cities that behave similarly. The set of required checkpoints is surprisingly small (10-124) despite the hundreds of thousands of road arcs in those areas, making it feasible to protect all major cities.« less

  11. Identifying security checkpoints locations to protect the major U.S. urban areas

    DOE PAGES

    Cuellar-Hengartner, Leticia; Watkins, Daniel; Kubicek, Deborah A.; ...

    2015-09-01

    Transit networks are integral to the economy and to society, but at the same time they could allow terrorists to transport weapons of mass destruction into any city. Road networks are especially vulnerable, because they lack natural checkpoints unlike air networks that have security measures in place at all major airports. One approach to mitigate this risk is ensuring that every road route passes through at least one security checkpoint. Using the Ford-Fulkerson maximum-flow algorithm, we generate a minimum set of checkpoint locations within a ring-shaped buffer area surrounding the 50 largest US urban areas. We study how the numbermore » of checkpoints changes as we increase the buffer width to perform a cost-benefit analysis and to identify groups of cities that behave similarly. The set of required checkpoints is surprisingly small (10-124) despite the hundreds of thousands of road arcs in those areas, making it feasible to protect all major cities.« less

  12. Roads influence movement and home ranges of a fragmentation-sensitive carnivore, the bobcat, in an urban landscape

    USGS Publications Warehouse

    Poessel, Sharon A; Boydston, Erin E.; Lyren, Lisa M.; Fisher, Robert N.; Burdett, Christopher L.; Alonso, Robert S.; Crooks, Kevin R.

    2014-01-01

    Roads in urbanized areas can impact carnivore populations by constraining their movements and increasing mortality. Bobcats (Lynx rufus) are felids capable of living in urban environments, but are sensitive to habitat fragmentation and, thus, useful indicators of landscape connectivity; in particular, bobcat habitat selection, movement, and mortality may be affected by roads. We analyzed movement patterns of 52 bobcats in southern California in three study sites and investigated: (1) how bobcats responded to two types of roads within their home ranges; (2) how they placed their home ranges with respect to roads within the study area; and (3) whether male and female bobcats differed in their behavioral responses to roads. Within home ranges, primary and secondary roads did not influence movements, but bobcats more frequently crossed secondary roads when road densities were higher within their home ranges, thus increasing mortality risk. However, road densities within each study site were several times higher than road densities within home ranges, suggesting bobcats selected against roaded areas in home-range placement. Male home ranges bordering roads were smaller than home ranges for other males, but male home ranges containing roads were larger than those without roads. Male bobcats also were more likely to cross roads than females, potentially reflecting larger male home range sizes. Our results suggest roads have important impacts on urban bobcats, with stronger effects on males than females, and continued efforts to mitigate the effects of roads on carnivores and other fragmentation-sensitive species would help promote connectivity conservation in urban systems.

  13. Plasma vitrification of asbestos fibers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Camacho, S.L.

    Asbestos is a mineral in the form of long, thread-like fibers. Asbestos fibers have been among the best insulators of pipes, boilers, ducts, tanks, etc., in buildings, ships, and industrial furnaces. Over 150,000 metric tons of asbestos were consumed in the United States in 1984. The Environmental Protection Agency has declared asbestos fibers a known human carcinogen. And today, asbestos insulators are being replaced by manmade non-hazardous fibers. Millions of tons of replaced asbestos fiber insulators are in storage, awaiting the demonstration of effective alternative disposal technologies. Plasma vitrification has been demonstrated during May, June and July 1995 as amore » viable, cost-effective, safe technology for asbestos fiber disposal. A low-mass plasma arc heater is submerged under the waste asbestos insulating materials, and the intense heat of the plasma flame heats and melts the fibers. The by-product is dark, non-hazardous glass pellets. The vitrification process renders the asbestos waste safe for use as road construction aggregates or other fill materials. This paper will describe the results of start-up of a 1 ton-per-hour Plasma Mobile Asbestos Vitrification (MAV) Plant at a DOD Site in Port Clinton, Ohio. The Plasma MAV Plant is being demonstrated for the on-site disposal of 1.5 million pounds of Amosite asbestos fibers.« less

  14. 75 FR 46914 - Certain New Pneumatic Off-the-Road Tires From the People's Republic of China: Final Results of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-04

    ... sites. They can also be used to perform ``rough grading'' in road construction. \\17\\ A straddle carrier... commonly used in maintenance of unpaved roads and road construction to prepare the base course on to which...-the-Road Tires From the People's Republic of China: Final Results of Changed Circumstances Review...

  15. Coherent random lasing controlled by Brownian motion of the active scatterer

    NASA Astrophysics Data System (ADS)

    Liang, Shuofeng; Yin, Leicheng; Zhang, ZhenZhen; Xia, Jiangying; Xie, Kang; Zou, Gang; Hu, Zhijia; Zhang, Qijin

    2018-05-01

    The stability of the scattering loop is fundamental for coherent random lasing in a dynamic scattering system. In this work, fluorescence of DPP (N, N-di [3-(isobutyl polyhedral oligomeric silsesquioxanes) propyl] perylene diimide) is scattered to produce RL and we realize the transition from incoherent RL to coherent RL by controlling the Brownian motion of the scatterers (dimer aggregates of DPP) and the stability of scattering loop. To produce coherent random lasers, the loop needs to maintain a stable state within the loop-stable time, which can be determined through controlled Brownian motion of scatterers in the scattering system. The result shows that the loop-stable time is within 5.83 × 10‑5 s to 1.61 × 10‑4 s based on the transition from coherent to incoherent random lasing. The time range could be tuned by finely controlling the viscosity of the solution. This work not only develops a method to predict the loop-stable time, but also develops the study between Brownian motion and random lasers, which opens the road to a variety of novel interdisciplinary investigations involving modern statistical mechanics and disordered photonics.

  16. Lidar arc scan uncertainty reduction through scanning geometry optimization

    NASA Astrophysics Data System (ADS)

    Wang, H.; Barthelmie, R. J.; Pryor, S. C.; Brown, G.

    2015-10-01

    Doppler lidars are frequently operated in a mode referred to as arc scans, wherein the lidar beam scans across a sector with a fixed elevation angle and the resulting measurements are used to derive an estimate of the n minute horizontal mean wind velocity (speed and direction). Previous studies have shown that the uncertainty in the measured wind speed originates from turbulent wind fluctuations and depends on the scan geometry (the arc span and the arc orientation). This paper is designed to provide guidance on optimal scan geometries for two key applications in the wind energy industry: wind turbine power performance analysis and annual energy production. We present a quantitative analysis of the retrieved wind speed uncertainty derived using a theoretical model with the assumption of isotropic and frozen turbulence, and observations from three sites that are onshore with flat terrain, onshore with complex terrain and offshore, respectively. The results from both the theoretical model and observations show that the uncertainty is scaled with the turbulence intensity such that the relative standard error on the 10 min mean wind speed is about 30 % of the turbulence intensity. The uncertainty in both retrieved wind speeds and derived wind energy production estimates can be reduced by aligning lidar beams with the dominant wind direction, increasing the arc span and lowering the number of beams per arc scan. Large arc spans should be used at sites with high turbulence intensity and/or large wind direction variation when arc scans are used for wind resource assessment.

  17. Contribution of Urban Road Traffic to PM2.5 Pollution

    EPA Science Inventory

    Overview of PM2.5 measurements from EPA's NAAQS monitoring sites across the US. The few measurements that exist show increased PM2.5 mass levels at near-road sites, consistent with measurements of other pollutants emitted by motor vehicles.

  18. Road to Recovery: Bringing Recovery to Small Town America

    ScienceCinema

    Nettamo, Paivi

    2018-01-08

    The Recovery Act hits the road to reach out to surrounding towns of the Savannah River Site that are struggling with soaring unemployment rates. This project helps recruit thousands of people to new jobs in environmental cleanup at the Savannah River Site.

  19. Human-Swarm Interactions Based on Managing Attractors

    DTIC Science & Technology

    2014-03-06

    Laboratory/ Brigham Young University Information Directorate Provo, UT 84602 Rome Research Site/ RISC 525 Brooks Road Rome NY 13441...Information Directorate Rome Research Site/ RISC 525 Brooks Road Rome NY 13441-4505 10. SPONSOR/MONITOR’S ACRONYM(S) AFRL/RI 11. SPONSORING

  20. 7. View from heat sink (south to north), west oblique ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. View from heat sink (south to north), west oblique of missile site control building, emphasizing southwest face - Stanley R. Mickelsen Safeguard Complex, Missile Site Control Building, Northeast of Tactical Road; southeast of Tactical Road South, Nekoma, Cavalier County, ND

  1. Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity.

    PubMed

    Skala, Wolfgang; Utzschneider, Daniel T; Magdolen, Viktor; Debela, Mekdes; Guo, Shihui; Craik, Charles S; Brandstetter, Hans; Goettig, Peter

    2014-12-05

    Human kallikrein-related peptidase 2 (KLK2) is a tryptic serine protease predominantly expressed in prostatic tissue and secreted into prostatic fluid, a major component of seminal fluid. Most likely it activates and complements chymotryptic KLK3 (prostate-specific antigen) in cleaving seminal clotting proteins, resulting in sperm liquefaction. KLK2 belongs to the "classical" KLKs 1-3, which share an extended 99- or kallikrein loop near their non-primed substrate binding site. Here, we report the 1.9 Å crystal structures of two KLK2-small molecule inhibitor complexes. In both structures discontinuous electron density for the 99-loop indicates that this loop is largely disordered. We provide evidence that the 99-loop is responsible for two biochemical peculiarities of KLK2, i.e. reversible inhibition by micromolar Zn(2+) concentrations and permanent inactivation by autocatalytic cleavage. Indeed, several 99-loop mutants of KLK2 displayed an altered susceptibility to Zn(2+), which located the Zn(2+) binding site at the 99-loop/active site interface. In addition, we identified an autolysis site between residues 95e and 95f in the 99-loop, whose elimination prevented the mature enzyme from limited autolysis and irreversible inactivation. An exhaustive comparison of KLK2 with related structures revealed that in the KLK family the 99-, 148-, and 220-loop exist in open and closed conformations, allowing or preventing substrate access, which extends the concept of conformational selection in trypsin-related proteases. Taken together, our novel biochemical and structural data on KLK2 identify its 99-loop as a key player in activity regulation. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

  2. Structure-Function Analyses of Human Kallikrein-related Peptidase 2 Establish the 99-Loop as Master Regulator of Activity*

    PubMed Central

    Skala, Wolfgang; Utzschneider, Daniel T.; Magdolen, Viktor; Debela, Mekdes; Guo, Shihui; Craik, Charles S.; Brandstetter, Hans; Goettig, Peter

    2014-01-01

    Human kallikrein-related peptidase 2 (KLK2) is a tryptic serine protease predominantly expressed in prostatic tissue and secreted into prostatic fluid, a major component of seminal fluid. Most likely it activates and complements chymotryptic KLK3 (prostate-specific antigen) in cleaving seminal clotting proteins, resulting in sperm liquefaction. KLK2 belongs to the “classical” KLKs 1–3, which share an extended 99- or kallikrein loop near their non-primed substrate binding site. Here, we report the 1.9 Å crystal structures of two KLK2-small molecule inhibitor complexes. In both structures discontinuous electron density for the 99-loop indicates that this loop is largely disordered. We provide evidence that the 99-loop is responsible for two biochemical peculiarities of KLK2, i.e. reversible inhibition by micromolar Zn2+ concentrations and permanent inactivation by autocatalytic cleavage. Indeed, several 99-loop mutants of KLK2 displayed an altered susceptibility to Zn2+, which located the Zn2+ binding site at the 99-loop/active site interface. In addition, we identified an autolysis site between residues 95e and 95f in the 99-loop, whose elimination prevented the mature enzyme from limited autolysis and irreversible inactivation. An exhaustive comparison of KLK2 with related structures revealed that in the KLK family the 99-, 148-, and 220-loop exist in open and closed conformations, allowing or preventing substrate access, which extends the concept of conformational selection in trypsin-related proteases. Taken together, our novel biochemical and structural data on KLK2 identify its 99-loop as a key player in activity regulation. PMID:25326387

  3. Plant STAND P-loop NTPases: a current perspective of genome distribution, evolution, and function : Plant STAND P-loop NTPases: genomic organization, evolution, and molecular mechanism models contribute broadly to plant pathogen defense.

    PubMed

    Arya, Preeti; Acharya, Vishal

    2018-02-01

    STAND P-loop NTPase is the common weapon used by plant and other organisms from all three kingdoms of life to defend themselves against pathogen invasion. The purpose of this study is to review comprehensively the latest finding of plant STAND P-loop NTPase related to their genomic distribution, evolution, and their mechanism of action. Earlier, the plant STAND P-loop NTPase known to be comprised of only NBS-LRRs/AP-ATPase/NB-ARC ATPase. However, recent finding suggests that genome of early green plants comprised of two types of STAND P-loop NTPases: (1) mammalian NACHT NTPases and (2) NBS-LRRs. Moreover, YchF (unconventional G protein and members of P-loop NTPase) subfamily has been reported to be exceptionally involved in biotic stress (in case of Oryza sativa), thereby a novel member of STAND P-loop NTPase in green plants. The lineage-specific expansion and genome duplication events are responsible for abundance of plant STAND P-loop NTPases; where "moderate tandem and low segmental duplication" trajectory followed in majority of plant species with few exception (equal contribution of tandem and segmental duplication). Since the past decades, systematic research is being investigated into NBS-LRR function supported the direct recognition of pathogen or pathogen effectors by the latest models proposed via 'integrated decoy' or 'sensor domains' model. Here, we integrate the recently published findings together with the previous literature on the genomic distribution, evolution, and distinct models proposed for functional molecular mechanism of plant STAND P-loop NTPases.

  4. 13. Missile site control building, third and fourth floor interior, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Missile site control building, third and fourth floor interior, showing east corner and former electrical equipment area, room #306. This building was salvaged and sealed in the 1970's; the lower floors also suffered flooding - Stanley R. Mickelsen Safeguard Complex, Missile Site Control Building, Northeast of Tactical Road; southeast of Tactical Road South, Nekoma, Cavalier County, ND

  5. 7 CFR Exhibit I to Subpart A of... - Guidelines for Seasonal Farm Labor Housing

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Parking. 301-5.1Safe and convenient all-weather roads shall be provided to connect the site and its improvements to the off-site public road. 301-5.2All-weather drives and parking shall be provided for tenants, and for trucks and buses as needed within the site. Driveways, parking areas and walkway locations...

  6. 7 CFR Exhibit I to Subpart A of... - Guidelines for Seasonal Farm Labor Housing

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Parking. 301-5.1Safe and convenient all-weather roads shall be provided to connect the site and its improvements to the off-site public road. 301-5.2All-weather drives and parking shall be provided for tenants, and for trucks and buses as needed within the site. Driveways, parking areas and walkway locations...

  7. Superfund Technology Evaluation Report: SITE Program Demonstration Test Shirco Pilot-Scale Infrared Incineration System at the Rose Township Demode Road Superfund Site Volume I

    EPA Science Inventory

    The Shirco Pilot-Scale Infrared Incineration System was evaluated during a series of seventeen test runs under varied operating conditions at the Demode Road Superfund Site located in Rose Township, Michigan. The tests sought to demonstrate the effectiveness of the unit and the t...

  8. Conformation-selective inhibitors reveal differences in the activation and phosphate-binding loops of the tyrosine kinases Abl and Src

    PubMed Central

    Hari, Sanjay B.; Perera, B. Gayani K.; Ranjitkar, Pratistha; Seeliger, Markus A.; Maly, Dustin J.

    2013-01-01

    Over the last decade, an increasingly diverse array of potent and selective inhibitors that target the ATP-binding sites of protein kinases have been developed. Many of these inhibitors, like the clinically approved drug imatinib (Gleevec), stabilize a specific catalytically inactive ATP-binding site conformation of their kinases targets. Imatinib is notable in that it is highly selective for its kinase target, Abl, over other closely-related tyrosine kinases, like Src. In addition, imatinib is highly sensitive to the phosphorylation state of Abl's activation loop, which is believed to be a general characteristic of all inhibitors that stabilize a similar inactive ATP-binding site conformation. In this report, we perform a systematic analysis of a diverse series of ATP-competitive inhibitors that stabilize a similar inactive ATP-binding site conformation as imatinib with the tyrosine kinases Src and Abl. In contrast to imatinib, many of these inhibitors have very similar potencies against Src and Abl. Furthermore, only a subset of this class of inhibitors is sensitive to the phosphorylation state of the activation loop of these kinases. In attempting to explain this observation, we have uncovered an unexpected correlation between Abl's activation loop and another flexible active site feature, called the phosphate-binding loop (p-loop). These studies shed light on how imatinib is able to obtain its high target selectivity and reveal how the conformational preference of flexible active site regions can vary between closely related kinases. PMID:24106839

  9. Structure of an APC3–APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome

    DOE PAGES

    Yamaguchi, Masaya; Yu, Shanshan; Qiao, Renping; ...

    2014-12-06

    The anaphase-promoting complex/cyclosome (APC/C) is a massive E3 ligase that controls mitosis by catalyzing ubiquitination of key cell cycle regulatory proteins. The APC/C assembly contains two subcomplexes: the “Platform” centers around a cullin-RING-like E3 ligase catalytic core; the “Arc Lamp” is a hub that mediates transient association with regulators and ubiquitination substrates. The Arc Lamp contains the small subunits APC16, CDC26, and APC13, and tetratricopeptide repeat (TPR) proteins (APC7, APC3, APC6, and APC8) that homodimerize and stack with quasi-2-fold symmetry. Within the APC/C complex, APC3 serves as center for regulation. APC3's TPR motifs recruit substrate-binding coactivators, CDC20 and CDH1, viamore » their C-terminal conserved Ile-Arg (IR) tail sequences. Human APC3 also binds APC16 and APC7 and contains a > 200-residue loop that is heavily phosphorylated during mitosis, although the basis for APC3 interactions and whether loop phosphorylation is required for ubiquitination are unclear. Here, we map the basis for human APC3 assembly with APC16 and APC7, report crystal structures of APC3Δloop alone and in complex with the C-terminal domain of APC16, and test roles of APC3's loop and IR tail binding surfaces in APC/C-catalyzed ubiquitination. The structures show how one APC16 binds asymmetrically to the symmetric APC3 dimer and, together with biochemistry and prior data, explain how APC16 recruits APC7 to APC3, show how APC3's C-terminal domain is rearranged in the full APC/C assembly, and visualize residues in the IR tail binding cleft important for coactivator-dependent ubiquitination. Overall, the results provide insights into assembly, regulation, and interactions of TPR proteins and the APC/C.« less

  10. Human Y-Family DNA Polymerase κ Is More Tolerant to Changes in Its Active Site Loop than Its Ortholog Escherichia coli DinB.

    PubMed

    Antczak, Nicole M; Packer, Morgan R; Lu, Xueguang; Zhang, Ke; Beuning, Penny J

    2017-11-20

    DNA damage is a constant threat and can be bypassed in a process called translesion synthesis, which is typically carried out by Y-family DNA polymerases. Y-family DNA polymerases are conserved in all domains of life and tend to have specificity for certain types of DNA damage. Escherichia coli DinB and its human ortholog pol κ can bypass specific minor groove deoxyguanine adducts efficiently and are inhibited by major groove adducts, as Y-family DNA polymerases make contacts with the minor groove side of the DNA substrate and lack contacts with the major groove at the nascent base pair. DinB is inhibited by major groove adducts more than pol κ, and they each have active site loops of different lengths, with four additional amino acids in the DinB loop. We previously showed that the R35A active site loop mutation in DinB allows for bypass of the major groove adduct N 6 -furfuryl-dA. These observations led us to investigate the different active site loops by creating loop swap chimeras of DinB with a pol κ loop and vice versa by changing the loop residues in a stepwise fashion. We then determined their activity with undamaged DNA or DNA containing N 2 -furfuryl-dG or N 6 -furfuryl-dA. The DinB proteins with the pol kappa loop have low activity on all templates but have decreased misincorporation compared to either wild-type protein. The kappa proteins with the DinB loop retain activity on all templates and have decreased misincorporation compared to either wild-type protein. We assessed the thermal stability of the proteins and observed an increase in stability in the presence of all DNA templates and additional increases generally only in the presence of the undamaged and N 2 -furfuryl-dG adduct and dCTP, which correlates with activity. Overall we find that pol κ is more tolerant to changes in the active site loop than DinB.

  11. View to the southwest of the antenna array, note the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View to the southwest of the antenna array, note the site fence in the foreground - Over-the-Horizon Backscatter Radar Network, Christmas Valley Radar Site Transmit Sector Four Antenna Array, On unnamed road west of Lost Forest Road, Christmas Valley, Lake County, OR

  12. Structure, Regulation, and Putative Function of the Arginine Deiminase System of Streptococcus suis

    PubMed Central

    Gruening, Petra; Fulde, Marcus; Valentin-Weigand, Peter; Goethe, Ralph

    2006-01-01

    Streptococcus suis is an important cause of infectious diseases in young pigs. Little is known about the virulence factors or protective antigens of S. suis. Recently, we have identified two proteins of the arginine deiminase system (ADS) of S. suis, which were temperature induced and expressed on the streptococcal surface (N. Winterhoff, R. Goethe, P. Gruening, M. Rohde, H. Kalisz, H. E. Smith, and P. Valentin-Weigand, J. Bacteriol. 184:6768-6776, 2002). In the present study, we analyzed the complete ADS of S. suis. Due to their homologies to the recently published S. gordonii ADS genes, the genes for arginine deiminase, ornithine carbamoyl-transferase, and carbamate kinase, which were previously designated adiS, octS, and ckS, respectively, were renamed arcA, arcB, and arcC, respectively. Our data revealed that arcA, arcB, and arcC of the S. suis ADS are transcribed from an operon (arcABC operon). Additionally, putative ADS-associated genes were cloned and sequenced which, however, did not belong to the arcABC operon. These were the flpS gene upstream of the arcABC operon with homology to the flp transcription regulator of S. gordonii and the arcD, arcT, arcH, and argR genes downstream of the arcABC operon with high homologies to a putative arginine-ornithine antiporter, a putative dipeptidase of S. gordonii, a putative β-N-acetylhexosaminidase of S. pneumoniae, and a putative arginine repressor of S. gordonii, respectively. The transcriptional start point of the arcABC operon was determined, and promoter analysis provided evidence that multiple factors contribute to the regulation of the ADS. Thus, a putative binding site for a transcription regulator of the Crp/Fnr family, an ArgR-binding site, and two cis-acting catabolite response elements were identified in the promoter-operator region of the operon. Consistent with this, we could demonstrate that the ADS of S. suis is inducible by arginine and reduced O2 tension and subject to carbon catabolite repression. Furthermore, comparing an arcA knockout mutant in which expression of the three operon-encoded proteins was abolished with the parental wild-type strain showed that the arcABC operon of S. suis contributes to survival under acidic conditions. PMID:16385025

  13. Structure, regulation, and putative function of the arginine deiminase system of Streptococcus suis.

    PubMed

    Gruening, Petra; Fulde, Marcus; Valentin-Weigand, Peter; Goethe, Ralph

    2006-01-01

    Streptococcus suis is an important cause of infectious diseases in young pigs. Little is known about the virulence factors or protective antigens of S. suis. Recently, we have identified two proteins of the arginine deiminase system (ADS) of S. suis, which were temperature induced and expressed on the streptococcal surface (N. Winterhoff, R. Goethe, P. Gruening, M. Rohde, H. Kalisz, H. E. Smith, and P. Valentin-Weigand, J. Bacteriol. 184:6768-6776, 2002). In the present study, we analyzed the complete ADS of S. suis. Due to their homologies to the recently published S. gordonii ADS genes, the genes for arginine deiminase, ornithine carbamoyl-transferase, and carbamate kinase, which were previously designated adiS, octS, and ckS, respectively, were renamed arcA, arcB, and arcC, respectively. Our data revealed that arcA, arcB, and arcC of the S. suis ADS are transcribed from an operon (arcABC operon). Additionally, putative ADS-associated genes were cloned and sequenced which, however, did not belong to the arcABC operon. These were the flpS gene upstream of the arcABC operon with homology to the flp transcription regulator of S. gordonii and the arcD, arcT, arcH, and argR genes downstream of the arcABC operon with high homologies to a putative arginine-ornithine antiporter, a putative dipeptidase of S. gordonii, a putative beta-N-acetylhexosaminidase of S. pneumoniae, and a putative arginine repressor of S. gordonii, respectively. The transcriptional start point of the arcABC operon was determined, and promoter analysis provided evidence that multiple factors contribute to the regulation of the ADS. Thus, a putative binding site for a transcription regulator of the Crp/Fnr family, an ArgR-binding site, and two cis-acting catabolite response elements were identified in the promoter-operator region of the operon. Consistent with this, we could demonstrate that the ADS of S. suis is inducible by arginine and reduced O2 tension and subject to carbon catabolite repression. Furthermore, comparing an arcA knockout mutant in which expression of the three operon-encoded proteins was abolished with the parental wild-type strain showed that the arcABC operon of S. suis contributes to survival under acidic conditions.

  14. An overview of road damages due to flooding: Case study in Kedah state, Malaysia

    NASA Astrophysics Data System (ADS)

    Ismail, Muhd Shahril Nizam; Ghani, Abdul Naser Abdul

    2017-10-01

    Flooding occurs frequently in many countries including Malaysia. Floods in Malaysia are usually due to heavy and prolonged rainfall, uncontrolled development, and drainage systems that are not being monitored. Road damage due to flooding event can cause huge expenditures for the post-flooding rehabilitation and maintenance. The required maintenance and rehabilitation could upset the original life cycle cost estimations. Data on road statistics were obtained from the Highway Planning Division, Ministry of Works Malaysia and data on flooding was collected from the Department of Irrigation and Drainage Malaysia for events between 2012 and 2015. The pilot sites were selected based on its historical cases of floods that caused road damages in Kedah. The pilot site indicated that the impact of flooding on road infrastructures systems can be used to plan better road design and maintenances. It also revealed that it costs more than RM 1 million to reinstate roads damaged by flooding in a typical district annually.

  15. Modeling of Thermal Treatment of Hazardous Solid Wastes in a DC Arc Melter.

    PubMed

    Wenger, Ashley; Farouk, Bakhtier; Wittle, Kenneth

    1996-12-01

    Ashley Wenger is a graduate student in the Mechanical Engineering and Mechanics (MEM) Department at Drexel University. Dr. Bakhtier Farouk is a professor in the MEM Department at Drexel University, 32nd and Chestnut Streets, Philadelphia, PA 19104. Dr. J. Kenneth Wittle is the vice president of Electro-Pyrolysis, Inc., Suite 1118, 996 Old Eagle School Road, Wayne, PA 19087. Please address all correspondence to Dr. Bakhtier Farouk.

  16. Decision Support for Road Decommissioning and Restoration by Using Genetic Algorithms and Dynamic Programming

    Treesearch

    Elizabeth A. Eschenbach; Rebecca Teasley; Carlos Diaz; Mary Ann Madej

    2007-01-01

    Sediment contributions from unpaved forest roads have contributed to the degradation of anadromous fisheries streams in the Pacific Northwest.Efforts to reduce this degradation have included road decommissioning and road upgrading. These expensive activities have usually been implemented on a site specific basis without considering the sediment...

  17. Characterisation of traffic-generated particulate matter in Copenhagen

    NASA Astrophysics Data System (ADS)

    Wåhlin, Peter; Berkowicz, Ruwim; Palmgren, Finn

    Fine and coarse fraction PM was simultaneously sampled with Dichotomous Stacked Filter Units at a road site and at an urban background site during both summer and winter periods. The collected mass was determined gravimetrically, and the contents of 26 elements were measured by Proton-Induced X-ray Emission (PIXE). NO x was monitored continuously at both sites. The road increments (road concentrations minus urban background concentrations) of PIXE elements, PM and NO x were analysed using the Constrained Physical Receptor Model (COPREM). Good agreement between the measured data and the model was achieved in both size fractions using four well-separated source profiles representing the emissions from exhaust, road/tyres, brakes and road salt. The analysis showed that the particles created by brake abrasion have aerodynamic diameters in the inhalable size range around 2.8 μm. This particle diameter is common mass median for a long list of heavy metals that are apportioned to the brakes source: Cr, Fe, Cu, Zn, Zr, Mo, Sn, Sb, Ba and Pb. Other significant contributions of Al, Si, K, Ca, Ti, Mn, Fe, Zn and Sr, mostly in the coarse particle fraction, are apportioned to the road/tyres source.

  18. A comparison of Freeze-Thaw in roads with passive microwave satellite observations from SMAP

    NASA Astrophysics Data System (ADS)

    Kraatz, S.; Jacobs, J. M.; Miller, H.; Daniel, J.

    2017-12-01

    Freeze-thaw (F/T) timings are relevant to both natural and manmade systems as they impact the global carbon budget, health of natural systems (forests) and the safety of roads and structures. The Soil Moisture Active Passive (SMAP) mission's two L-band radiometer F/T products are obtained at 36 km2 footprint and thus mostly observe the natural environment. Roadway temperature data are available from temperature data probes (TDP), which measure temperature from above the ground to 1.8 m depth below the pavement. Differences in F/T timing between natural (SMAP + in-situ cal/val sites) and engineered (road TDP) sites are investigated. Dates of F/T were estimated using a moving window with a threshold of 0oC. The process was repeated for TDP data for air, road surface and road bottom temperatures. The impact of this work is to explore 1) how TDP data corresponds to the new radiometer based F/T product, 2) differences in F/T between roads and natural sites, 3) whether SMAP F/T leads or lags TDP measurements and 4) the variability of F/T dates based on the temperature measurement depth.

  19. Influence of low impact development construction on pollutant process of road-deposited sediments and associated heavy metals.

    PubMed

    Ma, Yukun; Gong, Manli; Zhao, Hongtao; Li, Xuyong

    2018-02-01

    Intense Low-Impact Development (LID) construction in China could lead to increasingly severe stormwater and receiving water pollution due to the lack of appropriate regulation for mitigating pollution from LID construction. Samples of road-deposited sediments (RDS) were collected from 50 study sites at seven LID construction stages and four road hierarchies to analyze the pollution process and determine the size of the region influenced by LID construction. Six heavy metals were analyzed, and the RDS index model was adopted to estimate the potential heavy metal load washed off by stormwater runoff. Analysis of variance revealed that the excavation and gravel filling of rain gardens and excavation of porous pavements were critical LID construction stages that contributed the largest masses of RDS per unit area to road surfaces. Although the concentration of heavy metals at LID construction sites was lower than at sites without LID construction, the load of heavy metals washed off from LID construction was much higher. In addition, the sizes of regions influenced by accumulated RDS from LID construction descended in the following order: arterial road (600-775m)>collector road (150-200m)>access road (100-150m)>laneway (20-30m). According to the characteristics of LID construction at the study sites, the potential total solid loads in stormwater throughout China were estimated to reach 36,694t by 2020 and 146,777t by 2030. According to the results of analysis, several recommendations are provided for designing LID construction regulations to mitigate stormwater pollution. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Comparative metagenomics approaches to characterize the soil fungal communities of western coastal region, Saudi Arabia

    PubMed Central

    Fuller, Michael P.

    2017-01-01

    A total of 145007 reads were obtained from pyrosequencing for all the 4 samples. The total count ranged from 11,301,014 (Mecca old road) to 23,503,512 bp (Thuwal). A total of 460 fungal species belonging to 133 genera, 58 families, 33 orders, 13 classes and 4 phyla was identified across the four sites. The most abundant phylum at all four sites was Ascomycota followed by Basidiomycota. Four phyla (Ascomycota—99.31%, Basidiomycota—0.59%, Chytridiomycota—0.04%, Glomeromycota—0.03%) were detected in Khulais. Except for Glomeromycota, all phyla were detected at Mecca old road (Ascomycota—74.26%, Basidiomycota—25.71%, Chytridiomycota—0.01%) and Thuwal (Ascomycota—99.59%, Basidiomycota—0.40%, Chytridiomycota—0.002%); while only Ascomycota—90.98% and Basidiomycota—9.01% were detected in Asfan road. At the class level, Sordariomycetes was predominantly observed at Asfan road—59.88%, Khulais—68.26% and Thuwal—94.84%; while Pezizomycetes was dominant at Mecca old road—56.01%, was absent at Asfan road. Agaricomycetes was present only at Mecca old road—25.73%; while Tremellomycetes—5.77%, Malasseizomycetes—2.13% and Microbotryomycetes—1.10% were found only at Asfan road. The phylogenetic trees revealed that clear genus level differences are visible across all the four sites, with an overall predominance of Thielavia followed by Madurella, Aspergillus, and Gelasinospora. Chaetomium sp., Aspergillus caespitosus and Aspergillus sp. were found in moderate (Mecca old road and Thuwal) to abundant (Asfan road and Khulais) quantities. Thielavia sp., Thielavia hyalocarpa and Madurella sp. are found in moderate quantities at Khulais and Mecca old road, while in abundant levels at Asfan road and Thuwal. Fusarium equisati and F. oxysporum were detected at Thuwal and Khulais. Sordaria araneosa was present at Khulais, while Malasseiza globosa species was detected in moderate quantities across all sites except Khulais. PMID:28934322

  1. Toxin MqsR Cleaves Single-Stranded mRNA with Various 5 Ends

    DTIC Science & Technology

    2016-08-24

    either protein ORIGINAL RESEARCH Toxin MqsR cleaves single- stranded mRNA with various 5’ ends Nityananda Chowdhury1,*, Brian W. Kwan1,*, Louise C...in which a single 5′- GCU site was predicted to be single- stranded (ssRNA), double- stranded (dsRNA), in the loop of a stem - loop (slRNA), or in a...single- stranded 5′- GCU sites since cleavage was approximately 20- fold higher than cleavage seen with the 5′- GCU site in the stem - loop and

  2. Improving safety on rural local and tribal roads site safety analysis - user guide #1.

    DOT National Transportation Integrated Search

    2014-08-01

    This User Guide presents an example of how rural local and Tribal practitioners can study conditions at a preselected site. It demonstrates the step-by-step safety analysis process presented in Improving Safety on Rural Local and Tribal Roads Saf...

  3. 75 FR 48895 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List: Intent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ... Rogers Road Municipal Landfill Superfund Site AGENCY: Environmental Protection Agency. ACTION: Proposed... Delete the Rogers Road Municipal Landfill Superfund Site located near Jacksonville, Pulaski County... CERCLA, other than operation and maintenance and five-year reviews, have been completed. However, this...

  4. Optimization Review, Optimization Review, Sidney and Richardson Hill Road Landfills, Delaware County, New York

    EPA Pesticide Factsheets

    The Sidney Landfill site is located on Richardson Hill Road approximately 10 miles southeast of Sidney, New York. In March 1989, the site was added to the National Priorities List (NPL) based on investigations completed by the New York State Department...

  5. 1. View from missile site control building (southeast to northwest) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View from missile site control building (southeast to northwest) of universal missile building. Note earth mounding. On the far right can be seen the exit tunnel; the small "boxes" on top are the roof ventilators. This building was salvaged and sealed after site inactivation - Stanley R. Mickelsen Safeguard Complex, Universal Missile Building, Between Tactical Road South & Patrol Road, Nekoma, Cavalier County, ND

  6. AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10.

    PubMed

    Ovens, Matthew J; Davies, Andrew J; Wilson, Marieangela C; Murray, Clare M; Halestrap, Andrew P

    2010-01-15

    In the present study we characterize the properties of the potent MCT1 (monocarboxylate transporter 1) inhibitor AR-C155858. Inhibitor titrations of L-lactate transport by MCT1 in rat erythrocytes were used to determine the Ki value and number of AR-C155858-binding sites (Et) on MCT1 and the turnover number of the transporter (kcat). Derived values were 2.3+/-1.4 nM, 1.29+/-0.09 nmol per ml of packed cells and 12.2+/-1.1 s-1 respectively. When expressed in Xenopus laevis oocytes, MCT1 and MCT2 were potently inhibited by AR-C155858, whereas MCT4 was not. Inhibition of MCT1 was shown to be time-dependent, and the compound was also active when microinjected, suggesting that AR-C155858 probably enters the cell before binding to an intracellular site on MCT1. Measurement of the inhibitor sensitivity of several chimaeric transporters combining different domains of MCT1 and MCT4 revealed that the binding site for AR-C155858 is contained within the C-terminal half of MCT1, and involves TM (transmembrane) domains 7-10. This is consistent with previous data identifying Phe360 (in TM10) and Asp302 plus Arg306 (TM8) as key residues in substrate binding and translocation by MCT1. Measurement of the Km values of the chimaeras for L-lactate and pyruvate demonstrate that both the C- and N-terminal halves of the molecule influence transport kinetics consistent with our proposed molecular model of MCT1 and its translocation mechanism that requires Lys38 in TM1 in addition to Asp302 and Arg306 in TM8 [Wilson, Meredith, Bunnun, Sessions and Halestrap (2009) J. Biol. Chem. 284, 20011-20021].

  7. Geochemical Variation of Subducting Pacific Crust Along the Izu-Bonin Arc System and its Implications on the Generation of Arc Magmas

    NASA Astrophysics Data System (ADS)

    Durkin, K.; Castillo, P.; Abe, N.; Kaneko, R.; Straub, S. M.; Garcia, E. S. M.; Yan, Q.; Tamura, Y.

    2015-12-01

    Subduction zone magmatism primarily occurs due to flux melting of the mantle wedge that has been metasomatized by the slab component. The latter is enriched in volatiles and fluid-mobile elements and derived mainly from subducted sediments and altered oceanic crust (AOC). Subduction input has been linked to arc output in many studies, but this relationship is especially well documented in sedimented arc-trench systems. However, the Izu-Bonin system is sediment-poor, therefore the compositional and latitudinal variations (especially in Pb isotopes) of its arc magmas must be sourced from the subduction component originating primarily from the AOC. Pb is a very good tracer of recycled AOC that may contribute 50% or more of arc magma Pb. Izu-Bonin arc chemistry suggests a subduction influx of Indian-type crust, but the subducting crust sampled at ODP Site 1149 is Pacific-type. The discrepancy between subduction input and arc output calls into question the importance of the AOC as a source of the subduction component, and raises major concerns with our understanding of slab input. During the R/V Revelle 1412 cruise in late 2014, we successfully dredged vertical fault scarps at several sites from 27.5 N to 34.5 N, spanning a range of crustal ages that include a suggested compositional change at ~125 Ma. Major element data show an alkali enrichment towards the north of the study transect. Preliminary incompatible trace element data (e.g. Ba, Zr and Sr) data support this enrichment trend. Detailed mass balance calculations supported by Sr, Nd, Hf and especially Pb isotope analyses will be performed to evaluate whether the AOC controls the Pb isotope chemistry of the Izu-Bonin volcanic arc.

  8. R-chie: a web server and R package for visualizing RNA secondary structures

    PubMed Central

    Lai, Daniel; Proctor, Jeff R.; Zhu, Jing Yun A.; Meyer, Irmtraud M.

    2012-01-01

    Visually examining RNA structures can greatly aid in understanding their potential functional roles and in evaluating the performance of structure prediction algorithms. As many functional roles of RNA structures can already be studied given the secondary structure of the RNA, various methods have been devised for visualizing RNA secondary structures. Most of these methods depict a given RNA secondary structure as a planar graph consisting of base-paired stems interconnected by roundish loops. In this article, we present an alternative method of depicting RNA secondary structure as arc diagrams. This is well suited for structures that are difficult or impossible to represent as planar stem-loop diagrams. Arc diagrams can intuitively display pseudo-knotted structures, as well as transient and alternative structural features. In addition, they facilitate the comparison of known and predicted RNA secondary structures. An added benefit is that structure information can be displayed in conjunction with a corresponding multiple sequence alignments, thereby highlighting structure and primary sequence conservation and variation. We have implemented the visualization algorithm as a web server R-chie as well as a corresponding R package called R4RNA, which allows users to run the software locally and across a range of common operating systems. PMID:22434875

  9. Tracing subducted sediment inputs to the Ryukyu arc-Okinawa Trough system: Evidence from thallium isotopes

    NASA Astrophysics Data System (ADS)

    Shu, Yunchao; Nielsen, Sune G.; Zeng, Zhigang; Shinjo, Ryuichi; Blusztajn, Jerzy; Wang, Xiaoyuan; Chen, Shuai

    2017-11-01

    Sediments are actively subducted in virtually every arc worldwide. However, quantifying their contributions to arc lavas and thereby establishing budgets of how sediments participate in slab-mantle interaction is challenging. In this contribution we use thallium (Tl) abundances and isotopic compositions of lavas from the Ryukyu arc (including south Kyushu) and its back-arc basin, Okinawa Trough, to investigate the influence of sediments from arc to back-arc. We also present extensive geochemical data for sediments and altered oceanic crust (AOC) outboard of the northern (DSDP Sites 296, 442B, 443 and 444) and central (DSDP Sites 294 and 295) part of the Ryukyu arc. The Tl isotopic compositions of sediments change systematically from lighter outboard of northern Ryukyu arc to heavier outboard of central Ryukyu arc. The feature reflects the dominance of terrigenous material and pelagic sedimentation outboard of the northern and central Ryukyu arc, respectively. Central and northern sections of Ryukyu arc and Okinawa Trough display larger range of Tl isotopic variation than southern section, which is consistent with more pelagic provenance for sediments outboard of central and northern Ryukyu arcs than that of expected sediments outboard of southern Ryukyu arc. Identical Tl, Sr, Nd and Pb isotope variations are found when comparing arc and back arc lavas, which indicates that sediments fluxes also account for the Tl isotopic variations in the Okinawa Trough lavas. Two-end-member mixing models of Tl with Pb, Sr and Nd isotopes require sediment inputs of< 1%, 0.1-1% and 0.3-2% by weight to the depleted mantle source to account for all these isotopic compositions of lavas from northern, central and southern portion of the Ryukyu arc and Okinawa Trough. Bulk mixing between mantle and sediment end members predict very similar sediment fluxes when using Tl, Sr, Nd and Pb isotopes, which indicates that fractionation of these elements must have happened after mixing between mantle and sediments. This conclusion is corroborated by model calculations of mixing between sediment melts with fractionated Sr/Nd ratios and mantle wedge, which show that no arc lava plot on such mixing lines. Thus bulk sediment mixing, rather than sediment melt, is required for the generation of the lavas from the Ryukyu arc and Okinawa Trough. The requirement of bulk sediment mixing occurring before trace element fractionation in the sub-arc mantle is consistent with models where mélange layers form at the top of the slab and are the principle source material for arc lavas. In addition, the fact that sediment components observed in the Ryukyu arc and Okinawa Trough lavas are similar, suggests that transport of mélange material to the source regions of the arc and back arc is equally efficient. This feature is most readily explained if mélange material is transported from the slab as diapirs.

  10. 33. Site Plan: Custer Air Force Station, Battle Creek, Michigan, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. Site Plan: Custer Air Force Station, Battle Creek, Michigan, FD Radar Facilities-FPS-27, Electrical Plot Plan and Duet Details, USACOE, not date. - Fort Custer Military Reservation, P-67 Radar Station, .25 mile north of Dickman Road, east of Clark Road, Battle Creek, Calhoun County, MI

  11. 1. Photocopy of site plan, Dene Hendrick, delineator, 1977, for ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopy of site plan, Dene Hendrick, delineator, 1977, for the City of San Jose in cooperative agreement with the California Department of Transportation (from the San Jose Historical Museum). - Twin Oaks Dairy, Northwest of Metcalfe Road, off State Route 101 (Monterey Road), Coyote, Santa Clara County, CA

  12. Subjective Response to Road Traffic Noise.

    ERIC Educational Resources Information Center

    Griffiths, I. D.; Langdon, F. J.

    A study consisting of acoustic measurements at fourteen sites in the London area and 1200 interviews dealing with the effects of the noise conditions prevailing at each of these sites has been carried out with the object of developing acceptability criteria for traffic noise from roads in residential areas. Dissatisfaction with the noise…

  13. 28. Site Plan: AF Station P67, Fort Custer, Michigan, Plot ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. Site Plan: AF Station P-67, Fort Custer, Michigan, Plot Plan (to accompany FY 1956 project planning report), USACOE, 22 July 1954. - Fort Custer Military Reservation, P-67 Radar Station, .25 mile north of Dickman Road, east of Clark Road, Battle Creek, Calhoun County, MI

  14. 7 CFR 3555.201 - Site requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... contiguous to and have direct access from a street, road, or driveway. Streets and roads must be hard... needed maintenance will be provided. (4) The site must be supported by adequate utilities and water and wastewater disposal systems. Certain water and wastewater systems that are privately-owned may be acceptable...

  15. Simulating Coronal Loop Implosion and Compressible Wave Modes in a Flare Hit Active Region

    NASA Astrophysics Data System (ADS)

    Sarkar, Aveek; Vaidya, Bhargav; Hazra, Soumitra; Bhattacharyya, Jishnu

    2017-12-01

    There is considerable observational evidence of implosion of magnetic loop systems inside solar coronal active regions following high-energy events like solar flares. In this work, we propose that such collapse can be modeled in three dimensions quite accurately within the framework of ideal magnetohydrodynamics. We furthermore argue that the dynamics of loop implosion is only sensitive to the transmitted disturbance of one or more of the system variables, e.g., velocity generated at the event site. This indicates that to understand loop implosion, it is sensible to leave the event site out of the simulated active region. Toward our goal, a velocity pulse is introduced to model the transmitted disturbance generated at the event site. Magnetic field lines inside our simulated active region are traced in real time, and it is demonstrated that the subsequent dynamics of the simulated loops closely resemble observed imploding loops. Our work highlights the role of plasma β in regards to the rigidity of the loop systems and how that might affect the imploding loops’ dynamics. Compressible magnetohydrodynamic modes such as kink and sausage are also shown to be generated during such processes, in accordance with observations.

  16. 25 CFR 247.20 - What are the road and trail prohibitions?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What are the road and trail prohibitions? 247.20 Section... RIVER TREATY FISHING ACCESS SITES § 247.20 What are the road and trail prohibitions? (a) You cannot damage or leave in a damaged condition any road, trail, or segment thereof. (b) You cannot block...

  17. Research related to roads in USDA experimental forests [Chapter 16

    Treesearch

    W. J. Elliot; P. J. Edwards; R. B. Foltz

    2014-01-01

    Forest roads are essential in experimental forests and rangelands (EFRs) to allow researchers and the public access to research sites and for fire suppression, timber extraction, and fuel management. Sediment from roads can adversely impact watershed health. Since the 1930s, the design and management of forest roads has addressed both access issues and watershed health...

  18. Osmotic mechanism of the loop extrusion process

    NASA Astrophysics Data System (ADS)

    Yamamoto, Tetsuya; Schiessel, Helmut

    2017-09-01

    The loop extrusion theory assumes that protein factors, such as cohesin rings, act as molecular motors that extrude chromatin loops. However, recent single molecule experiments have shown that cohesin does not show motor activity. To predict the physical mechanism involved in loop extrusion, we here theoretically analyze the dynamics of cohesin rings on a loop, where a cohesin loader is in the middle and unloaders at the ends. Cohesin monomers bind to the loader rather frequently and cohesin dimers bind to this site only occasionally. Our theory predicts that a cohesin dimer extrudes loops by the osmotic pressure of cohesin monomers on the chromatin fiber between the two connected rings. With this mechanism, the frequency of the interactions between chromatin segments depends on the loading and unloading rates of dimers at the corresponding sites.

  19. Environmental Assessment and Final Finding of No Significant Impact for Lantirn Village & Camera I Site Upgrades Fort Wainwright Yukon Training Area Fort Wainwright, Alaska

    DTIC Science & Technology

    2009-08-01

    improved road access and overhead power. The site contains a WISS shelter, five (5) 40’ connex containers, UMTE pedestal, shelter, and a weather ...monitoring station (Figure 3- 1 ). 3.1.8.3 Camera I site consists of a roughly l acre site with semi-improved road access and overhead power. The site...characteristics such as microclimate , soil temperature, and moisture regimes. which in turn influence the type of vegetation that will be found there

  20. Road Weather Systems [SD .WMV (720x480/29fps/25.2 MB)

    DOT National Transportation Integrated Search

    2009-01-01

    Iowas road weather information system at work. The Iowa DOT will install new sensors and upgrades to most road weather information system (RWIS) sites. These include: : color cameras, new precipitation sensors, new speed sensors, revised weathervi...

  1. A molecular mechanism of P-loop pliability of Rho-kinase investigated by molecular dynamic simulation

    NASA Astrophysics Data System (ADS)

    Gohda, Keigo; Hakoshima, Toshio

    2008-11-01

    Rho-kinase is a leading player in the regulation of cytoskeletal events involving smooth muscle contraction and neurite growth-cone collapse and retraction, and is a promising drug target in the treatment of both vascular and neurological disorders. Recent crystal structure of Rho-kinase complexed with a small-molecule inhibitor fasudil has revealed structural details of the ATP-binding site, which represents the target site for the inhibitor, and showed that the conserved phenylalanine on the P-loop occupies the pocket, resulting in an increase of protein-ligand contacts. Thus, the P-loop pliability is considered to play an important role in inhibitor binding affinity and specificity. In this study, we carried out a molecular dynamic simulation for Rho-kinase-fasudil complexes with two different P-loop conformations, i.e., the extended and folded conformations, in order to understand the P-loop pliability and dynamics at atomic level. A PKA-fasudil complex was also used for comparison. In the MD simulation, the flip-flop movement of the P-loop conformation starting either from the extended or folded conformation was not able to be observed. However, a significant conformational change in a long loop region covering over the P-loop, and also alteration of ionic interaction-manner of fasudil with acidic residues in the ATP binding site were shown only in the Rho-kinase-fasudil complex with the extended P-loop conformation, while Rho-kinase with the folded P-loop conformation and PKA complexes did not show large fluctuations, suggesting that the Rho-kinase-fasudil complex with the extended P-loop conformation represents a meta-stable state. The information of the P-loop pliability at atomic level obtained in this study could provide valuable clues to designing potent and/or selective inhibitors for Rho-kinase.

  2. An experimental evaluation of potential scavenger effects on snake road mortality detections

    USGS Publications Warehouse

    Hubbard, Kaylan A.; Chalfoun, Anna D.

    2012-01-01

    As road networks expand and collisions between vehicles and wildlife become more common, accurately quantifying mortality rates for the taxa that are most impacted will be critical. Snakes are especially vulnerable to collisions with vehicles because of their physiology and behavior. Reptile road mortality is typically quantified using driving or walking surveys; however, scavengers can rapidly remove carcasses from the road and cause underestimation of mortality. Our objective was to determine the effect that scavengers might have had on our ability to accurately detect reptile road mortality during over 150 h and 4,000 km of driving surveys through arid shrublands in southwest Wyoming, which resulted in only two observations of mortality. We developed unique simulated snake carcasses out of Burbot (Lota lota), a locally invasive fish species, and examined removal rates across three different road types at three study sites. Carcass size was not a significant predictor of time of removal, and carcass removal was comparable during the daytime and nighttime hours. However, removal of simulated carcasses was higher on paved roads than unpaved or two-track roads at all study sites, with an average of 75% of the carcasses missing within 60 h compared to 34% and 31%, respectively. Scavengers may therefore negatively impact the ability of researchers to accurately detect herpetofaunal road mortality, especially for paved roads where road mortality is likely the most prevalent.

  3. MX Siting Investigation. MX System Siting Summary Report. General Introduction. Volume I. Part I.

    DTIC Science & Technology

    1982-01-18

    Mountain Spring Peak 1972 Observation Knoll 1971 Pinto Spring 1971 Steamboat Mountain 1971 Steamboat Mountain SW 1971 The Tetons 1971 Zane 1972 MX SITING...Silver Peak 1978 Stoddard Mountain 1978 Water Creek Canyon 1972 Yale Crossing 1971 49 Beaver Dam Mountains NE 1955 Central East 1972 Central West 1972...SHELTER SITE -ORIGINAL ROAD --- RESITED ROAD *• = FOUND 3 1/2" BRASS CAP SET ON 2 1/2" IRON PIPE . U.S DEPARTMENT OF THE INTERIOR. BUREAU OF LAND

  4. Not just a rural occurrence: differences in agricultural equipment crash characteristics by rural-urban crash site and proximity to town.

    PubMed

    Harland, Karisa K; Greenan, Mitchell; Ramirez, Marizen

    2014-09-01

    Although approximately one-third of agricultural equipment-related crashes occur near town, these crashes are thought to be a rural problem. This analysis examines differences between agricultural equipment-related crashes by their urban-rural distribution and distance from a town. Agricultural equipment crashes were collected from nine Midwest Departments of Transportation (2005-2008). Crash zip code was assigned as urban or rural (large, small and isolated) using Rural-Urban Commuting Areas. Crash proximity to a town was estimated with ArcGIS. Multivariable logistic regression was used to estimate the odds of crashing in an urban versus rural zip codes and across rural gradients. ANOVA analysis estimated mean distance (miles) from a crash site to a town. Over four years, 4444 crashes involved agricultural equipment. About 30% of crashes occurred in urban zip codes. Urban crashes were more likely to be non-collisions (aOR=1.69[1.24-2.30]), involve ≥2 vehicles (2 vehicles: aOR=1.58[1.14-2.20], 3+ vehicles: aOR=1.68[0.98-2.88]), occur in a town (aOR=2.06[1.73-2.45]) and within one mile of a town (aOR=1.65[1.40-1.95]) than rural crashes. The proportion of crashes within a town differed significantly across rural gradients (P<0.0001). Small rural crashes, compared to isolated rural crashes, were 1.98 (95%CI[1.28-3.06]) times more likely to be non-collisions. The distance from the crash to town differed significantly by the urban-rural distribution (P<0.0001). Crashes with agricultural equipment are unexpectedly common in urban areas and near towns and cities. Education among all roadway users, increased visibility of agricultural equipment and the development of complete rural roads are needed to increase road safety and prevent agricultural equipment-related crashes. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Short arc orbit determination for altimeter calibration and validation on TOPEX/POSEIDON

    NASA Technical Reports Server (NTRS)

    Williams, B. G.; Christensen, E. J.; Yuan, D. N.; Mccoll, K. C.; Sunseri, R. F.

    1993-01-01

    TOPEX/POSEIDON (T/P) is a joint mission of United States' National Aeronautics and Space Administration (NASA) and French Centre National d'Etudes Spatiales (CNES) design launched August 10, 1992. It carries two radar altimeters which alternately share a common antenna. There are two project designated verification sites, a NASA site off the coast at Pt. Conception, CA and a CNES site near Lampedusa Island in the Mediterranean Sea. Altimeter calibration and validation for T/P is performed over these highly instrumented sites by comparing the spacecraft's altimeter radar range to computed range based on in situ measurements which include the estimated orbit position. This paper presents selected results of orbit determination over each of these sites to support altimeter verification. A short arc orbit determination technique is used to estimate a locally accurate position determination of T/P from less than one revolution of satellite laser ranging (SLR) data. This technique is relatively insensitive to gravitational and non-gravitational force modeling errors and is demonstrated by covariance analysis and by comparison to orbits determined from longer arcs of data and other tracking data types, such as Doppler Orbitography and Radiopositioning Integrated by Satellite (DORIS) and Global Positioning System Demonstration Receiver (GPSDR) data.

  6. Digital geologic map of part of the Thompson Falls 1:100,000 quadrangle, Idaho

    USGS Publications Warehouse

    Lewis, Reed S.; Derkey, Pamela D.

    1999-01-01

    The geology of the Thompson Falls 1:100,000 quadrangle, Idaho was compiled by Reed S. Lewis in 1997 onto a 1:100,000-scale greenline mylar of the topographic base map for input into a geographic information system (GIS). The resulting digital geologic map GIS can be queried in many ways to produce a variety of geologic maps. Digital base map data files (topography, roads, towns, rivers and lakes, etc.) are not included: they may be obtained from a variety of commercial and government sources. This database is not meant to be used or displayed at any scale larger than 1:100,000 (e.g., 1:62,500 or 1:24,000). The map area is located in north Idaho. This open-file report describes the geologic map units, the methods used to convert the geologic map data into a digital format, the Arc/Info GIS file structures and relationships, and explains how to download the digital files from the U.S. Geological Survey public access World Wide Web site on the Internet.

  7. Local evaluation report for ATLAS-ITS phase II : integration of real-time traffic information for adaptive signal control, traveler information and management of transit and emergency services

    DOT National Transportation Integrated Search

    2005-12-01

    Major roads and arterials in the City of Tucson and Pima County are already significantly detectorized with inductive loop detectors and, at places, with video-based detectors. These detectors are used for semi-actuated signal control and for limited...

  8. Transcription and replication: breaking the rules of the road causes genomic instability.

    PubMed

    Poveda, Ana Maria; Le Clech, Mikael; Pasero, Philippe

    2010-01-01

    Replication and transcription machineries progress at high speed on the same DNA template, which inevitably causes traffic accidents. Problems are not only caused by frontal collisions between polymerases, but also by cotranscriptional R-loops. These RNA-DNA hybrids induce genomic instability by blocking fork progression and could be implicated in the development of cancer.

  9. 36 CFR 7.45 - Everglades National Park.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... fishing services, for hire, to visitors of the park. (6) Minnow means a fish used for bait from the family... to fishing, including, but not limited to species of fish that may be taken, seasons and hours during... meridian and base, in the vicinity of Shark Valley Loop Road from Tamiami Trail south. (4) A person engaged...

  10. 36 CFR 7.45 - Everglades National Park.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... fishing services, for hire, to visitors of the park. (6) Minnow means a fish used for bait from the family... to fishing, including, but not limited to species of fish that may be taken, seasons and hours during... meridian and base, in the vicinity of Shark Valley Loop Road from Tamiami Trail south. (4) A person engaged...

  11. Lidar arc scan uncertainty reduction through scanning geometry optimization

    NASA Astrophysics Data System (ADS)

    Wang, Hui; Barthelmie, Rebecca J.; Pryor, Sara C.; Brown, Gareth.

    2016-04-01

    Doppler lidars are frequently operated in a mode referred to as arc scans, wherein the lidar beam scans across a sector with a fixed elevation angle and the resulting measurements are used to derive an estimate of the n minute horizontal mean wind velocity (speed and direction). Previous studies have shown that the uncertainty in the measured wind speed originates from turbulent wind fluctuations and depends on the scan geometry (the arc span and the arc orientation). This paper is designed to provide guidance on optimal scan geometries for two key applications in the wind energy industry: wind turbine power performance analysis and annual energy production prediction. We present a quantitative analysis of the retrieved wind speed uncertainty derived using a theoretical model with the assumption of isotropic and frozen turbulence, and observations from three sites that are onshore with flat terrain, onshore with complex terrain and offshore, respectively. The results from both the theoretical model and observations show that the uncertainty is scaled with the turbulence intensity such that the relative standard error on the 10 min mean wind speed is about 30 % of the turbulence intensity. The uncertainty in both retrieved wind speeds and derived wind energy production estimates can be reduced by aligning lidar beams with the dominant wind direction, increasing the arc span and lowering the number of beams per arc scan. Large arc spans should be used at sites with high turbulence intensity and/or large wind direction variation.

  12. Road traffic injury on rural roads in Tanzania: measuring the effectiveness of a road safety program.

    PubMed

    Zimmerman, Karen; Jinadasa, Deepani; Maegga, Bertha; Guerrero, Alejandro

    2015-01-01

    Road traffic injuries (RTIs) are a major public health burden, especially in low- and middle-income countries. There is limited data on RTIs in low-volume, rural African settings. This study attempted to survey all individuals living in households within 200 m of two low-volume rural roads in Tanzania and to collect data on RTIs. Local communities and users of the Bago to Talawanda road (intervention site) and Kikaro to Mihuga road (control site) were targeted and received an intensive program of road safety measures tailored using the crash characteristics of the baseline sample. Demographic data on all household members were collected, and those individuals who suffered an RTI in the previous 3 months had comprehensive information collected about the crash characteristics and the socioeconomic impact. The follow-up data collection occurred nine months after the baseline data were collected. The majority of crashes that caused an RTI involved a motorcycle (71%) and the majority of victims were male (82%) with an average age of 27. Injuries to the legs (55%) were most common and the average length of time away from normal activity was 27 (±33) days. RTI incidence at the intervention site increased during the course of the study (incidence before vs. incidence after) and was unchanged in the community control (incidence before vs. incidence after). The incidence of RTIs in the low-volume rural setting is unacceptably high and most commonly associated with motorcycles. The change in incidence is unreliable due to logistic restraints of the project and more research is needed to quantify the impact of various RTI prevention strategies in this setting. This study provides insight into road traffic injuries on low-volume rural roads, areas where very little research has been captured. Additionally, it provides a replicable study design for those interested in collecting similar data on low-volume rural roads.

  13. Variation of wave speed determined by the PU-loop with proximity to a reflection site.

    PubMed

    Li, Ye; Borlotti, Alessandra; Parker, Kim H; Khir, Ashraf W

    2011-01-01

    Wave speed is directly related to arterial distensibility and is widely used by clinicians to assess arterial stiffness. The PU-loop method for determining wave speed is based on the water hammer equation for flow in flexible tubes and artery using the method of characteristics. This technique determines wave speed using simultaneous measurements of pressure and velocity at a single point. The method shows that during the early part of systole, the relationship between pressure and velocity is generally linear, and the initial slope of the PU-loop is proportional to wave speed. In this work, we designed an in-vitro experiment to investigate the effect of proximity to a reflection site on the wave speed determined by the PU-loop through varying the distance between the measurement and reflection sites. Measurements were made in a flexible tube with a reflection site at the distal end formed by joining the tube to another tube with a different diameter and material properties. Six different flexible tubes were used to generate both positive and negative reflection coefficients of different magnitudes. We found that the wave speed determined by the PU-loop did not change when the measurement site was far from the reflection site but did change as the distance to the reflection site decreased. The calculated wave speed increased with positive reflections and decreased with negative reflections. The magnitude of the change in wave speed at a fixed distance from the reflection site increased with increasing the value of the reflection coefficient.

  14. Tectonic evolution of the outer Izu-Bonin-Mariana fore arc system: initial results from IODP Expedition 352

    NASA Astrophysics Data System (ADS)

    Kurz, W.; Ferre, E. C.; Robertson, A. H. F.; Avery, A. J.; Kutterolf, S.

    2015-12-01

    During International Ocean Discovery Program (IODP) Expedition 352, a section through the volcanic stratigraphy of the outer fore arc of the Izu-Bonin-Mariana (IBM) system was drilled to trace magmatism, tectonics, and crustal accretion associated with subduction initiation. Structures within drill cores, borehole and site survey seismic data indicate that tectonic deformation in the outer IBM fore arc is mainly post-magmatic. Extension generated asymmetric sediment basins such as half-grabens at sites 352-U1439 and 352-U1442 on the upper trench slope. Along their eastern margins the basins are bounded by west-dipping normal faults. Deformation was localized along multiple sets of faults, accompanied by syn-tectonic pelagic and volcaniclastic sedimentation. The lowermost sedimentary units were tilted eastward by ~20°. Tilted beds were covered by sub-horizontal beds. Biostratigraphic constraints reveal a minimum age of the oldest sediments at ~ 35 Ma; timing of the sedimentary unconformities is between ~ 27 and 32 Ma. At sites 352-U1440 and 352-U1441 on the outer fore arc strike-slip faults are bounding sediment basins. Sediments were not significantly affected by tectonic tilting. Biostratigraphy gives a minimum age of the basement-cover contact between ~29.5 and 32 Ma. The post-magmatic structures reveal a multiphase tectonic evolution of the outer IBM fore arc. At sites 352-U1439 and 352-U1442, shear with dominant reverse to oblique reverse displacement was localized along subhorizontal fault zones, steep slickensides and shear fractures. These were either re-activated as or cut by normal-faults and strike-slip faults. Extension was also accommodated by steep to subvertical mineralized veins and extensional fractures. Faults at sites 352-U1440 and 352-U1441 show mainly strike-slip kinematics. Sediments overlying the igneous basement(maximum Late Eocene to Recent age), document ash and aeolian input, together with mass wasting of the fault-bounded sediment ponds.

  15. Fretting Wear-Resistant, Micro-Arc Oxidation Coatings for Aluminum and Titanium Alloy Bearings (Preprint)

    DTIC Science & Technology

    2007-03-01

    Cushman, Infoscitex Corporation, 303 Bear Hill Road, Waltham, MA 02451 Aluminum and titanium alloys are used as replacements for steel in gear...assess the susceptibility of selected substrates to wear. Initial testing utilized M50 steel rings as the counter surface to uncoated aluminum and...were recorded and plotted over the 4500 cycles, as shown in the right of Figure 3, depicting results of the best performing test substrate, M50 Steel

  16. The I domain of the AAA+ HslUV protease coordinates substrate binding, ATP hydrolysis, and protein degradation

    PubMed Central

    Sundar, Shankar; Baker, Tania A; Sauer, Robert T

    2012-01-01

    In the AAA+ HslUV protease, substrates are bound and unfolded by a ring hexamer of HslU, before translocation through an axial pore and into the HslV degradation chamber. Here, we show that the N-terminal residues of an Arc substrate initially bind in the HslU axial pore, with key contacts mediated by a pore loop that is highly conserved in all AAA+ unfoldases. Disordered loops from the six intermediate domains of the HslU hexamer project into a funnel-shaped cavity above the pore and are positioned to contact protein substrates. Mutations in these I-domain loops increase KM and decrease Vmax for degradation, increase the mobility of bound substrates, and prevent substrate stimulation of ATP hydrolysis. HslU-ΔI has negligible ATPase activity. Thus, the I domain plays an active role in coordinating substrate binding, ATP hydrolysis, and protein degradation by the HslUV proteolytic machine. PMID:22102327

  17. Robustness study of the pseudo open-loop controller for multiconjugate adaptive optics.

    PubMed

    Piatrou, Piotr; Gilles, Luc

    2005-02-20

    Robustness of the recently proposed "pseudo open-loop control" algorithm against various system errors has been investigated for the representative example of the Gemini-South 8-m telescope multiconjugate adaptive-optics system. The existing model to represent the adaptive-optics system with pseudo open-loop control has been modified to account for misalignments, noise and calibration errors in deformable mirrors, and wave-front sensors. Comparison with the conventional least-squares control model has been done. We show with the aid of both transfer-function pole-placement analysis and Monte Carlo simulations that POLC remains remarkably stable and robust against very large levels of system errors and outperforms in this respect least-squares control. Approximate stability margins as well as performance metrics such as Strehl ratios and rms wave-front residuals averaged over a 1-arc min field of view have been computed for different types and levels of system errors to quantify the expected performance degradation.

  18. The Human Genome Project and Mental Retardation: An Educational Program. Final Progress Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, Sharon

    The Arc, a national organization on mental retardation, conducted an educational program for members, many of whom have a family member with a genetic condition causing mental retardation. The project informed members about the Human Genome scientific efforts, conducted training regarding ethical, legal and social implications and involved members in issue discussions. Short reports and fact sheets on genetic and ELSI topics were disseminated to 2,200 of the Arc's leaders across the country and to other interested individuals. Materials produced by the project can e found on the Arc's web site, TheArc.org.

  19. FAST TRACK COMMUNICATION: A Temperley-Lieb quantum chain with two- and three-site interactions

    NASA Astrophysics Data System (ADS)

    Ikhlef, Y.; Jacobsen, J. L.; Saleur, H.

    2009-07-01

    We study the phase diagram of a quantum chain of spin-1/2 particles whose world lines form a dense loop gas with loop weight n. In addition to the usual two-site interaction corresponding to the XXZ spin chain, we introduce a three-site interaction. The resulting model contains a Majumdar-Ghosh-like gapped phase and a new integrable point, which we solve exactly. We also locate a critical line realizing dilute O(n) criticality, without introducing explicit dilution in the loops. Our results have implications for anisotropic spin chains, as well as anyonic quantum chains.

  20. Predicting risk of trace element pollution from municipal roads using site-specific soil samples and remotely sensed data.

    PubMed

    Reeves, Mari Kathryn; Perdue, Margaret; Munk, Lee Ann; Hagedorn, Birgit

    2018-07-15

    Studies of environmental processes exhibit spatial variation within data sets. The ability to derive predictions of risk from field data is a critical path forward in understanding the data and applying the information to land and resource management. Thanks to recent advances in predictive modeling, open source software, and computing, the power to do this is within grasp. This article provides an example of how we predicted relative trace element pollution risk from roads across a region by combining site specific trace element data in soils with regional land cover and planning information in a predictive model framework. In the Kenai Peninsula of Alaska, we sampled 36 sites (191 soil samples) adjacent to roads for trace elements. We then combined this site specific data with freely-available land cover and urban planning data to derive a predictive model of landscape scale environmental risk. We used six different model algorithms to analyze the dataset, comparing these in terms of their predictive abilities and the variables identified as important. Based on comparable predictive abilities (mean R 2 from 30 to 35% and mean root mean square error from 65 to 68%), we averaged all six model outputs to predict relative levels of trace element deposition in soils-given the road surface, traffic volume, sample distance from the road, land cover category, and impervious surface percentage. Mapped predictions of environmental risk from toxic trace element pollution can show land managers and transportation planners where to prioritize road renewal or maintenance by each road segment's relative environmental and human health risk. Published by Elsevier B.V.

  1. Magma Differentiation Processes That Develop an "Enriched" Signature in the Izu Bonin Rear Arc: Evidence from Drilling at IODP Site U1437

    NASA Astrophysics Data System (ADS)

    Heywood, L. J.; DeBari, S. M.; Schindlbeck, J. C.; Escobar-Burciaga, R. D.

    2015-12-01

    The Izu Bonin rear arc represents a unique laboratory to study the development of continental crust precursors at an intraoceanic subduction zone., Volcanic output in the Izu Bonin rear arc is compositionally distinct from the Izu Bonin main volcanic front, with med- to high-K and LREE-enrichment similar to the average composition of the continental crust. Drilling at IODP Expedition 350 Site U1437 in the Izu Bonin rear arc obtained volcaniclastic material that was deposited from at least 13.5 Ma to present. IODP Expedition 350 represents the first drilling mission in the Izu Bonin rear arc region. This study presents fresh glass and mineral compositions (obtained via EMP and LA-ICP-MS) from unaltered tephra layers in mud/mudstone (Lithostratigraphic Unit I) and lapillistone (Lithostratigraphic Unit II) <4.5 Ma to examine the geochemical signature of Izu Bonin rear arc magmas. Unit II samples are coarse-grained tephras that are mainly rhyolitic in composition (72.1-77.5 wt. % SiO2, 3.2-3.9 wt. % K2O and average Mg# 24) and LREE-enriched. These rear-arc rhyolites have an average La/Sm of 2.6 with flat HREEs, average Th/La of 0.15, and Zr/Y of 4.86. Rear-arc rhyolite trace element signature is distinct from felsic eruptive products from the Izu Bonin main volcanic front, which have lower La/Sm and Th/La as well as significantly lower incompatible element concentrations. Rear arc rhyolites have similar trace element ratios to rhyolites from the adjacent but younger backarc knolls and actively-extending rift regions, but the latter is typified by lower K2O, as well as a smaller degree of enrichment in incompatible elements. Given these unique characteristics, we explore models for felsic magma formation and intracrustal differentiation in the Izu Bonin rear arc.

  2. Environmental impact assessment of wood ash utilization in forest road construction and maintenance--A field study.

    PubMed

    Oburger, Eva; Jäger, Anna; Pasch, Alexander; Dellantonio, Alex; Stampfer, Karl; Wenzel, Walter W

    2016-02-15

    The ever increasing use of wood material as fuel for green energy production requires innovative, environmentally safe strategies for recycling of the remaining wood ash. Utilizing wood ash in forest road construction and maintenance to improve mechanical stability has been suggested as a feasible recycling option. To investigate the environmental impact of wood ash application in forest road maintenance, a two-year field experiment was conducted at two Austrian forest sites (Kobernausserwald (KO) (soil pH 5.5) and Weyregg (WE) (pH 7.7)) differing in their soil chemical properties. Two different ashes, one produced by grate incineration (GA) and the other by fluidized bed incineration in a mixture with 15 vol% burnt lime (FBA), were incorporated in repeated road sections at a 15:85% (V/V) ash-to-soil rate. Leaching waters from the road body were collected and analyzed for 32 environmentally relevant parameters over two years. Upon termination of the experiment, sub-road soil samples were collected and analyzed for ash-related changes in soil chemistry. Even though a larger number of parameters was affected by the ash application at the alkaline site (WE), we observed the most pronounced initial increases of pH as well as Al, As, Fe, Mn, Ni, Co, Cu, Mo, and NO2(−) concentrations in leachates beneath GA-treated road bodies at Kobernausserwald due to the lower soil buffer capacity at this site. Despite the observed effects our results indicate that, when specific requirements are met (i.e. appropriate ash quality, sufficient soil buffer capacity below the road body, and single time-point ash incorporation within several decades), wood ash application in forest road construction is generally environmentally acceptable.

  3. Do unpaved, low-traffic roads affect bird communities?

    NASA Astrophysics Data System (ADS)

    Mammides, Christos; Kounnamas, Constantinos; Goodale, Eben; Kadis, Costas

    2016-02-01

    Unpaved, low traffic roads are often assumed to have minimal effects on biodiversity. To explore this assertion, we sampled the bird communities in fifteen randomly selected sites in Pafos Forest, Cyprus and used multiple regression to quantify the effects of such roads on the total species richness. Moreover, we classified birds according to their migratory status and their global population trends, and tested each category separately. Besides the total length of unpaved roads, we also tested: a. the site's habitat diversity, b. the coefficient of variation in habitat (patch) size, c. the distance to the nearest agricultural field, and d. the human population size of the nearest village. We measured our variables at six different distances from the bird point-count locations. We found a strong negative relationship between the total bird richness and the total length of unpaved roads. The human population size of the nearest village also had a negative effect. Habitat diversity was positively related to species richness. When the categories were tested, we found that the passage migrants were influenced more by the road network while resident breeders were influenced by habitat diversity. Species with increasing and stable populations were only marginally affected by the variables tested, but the effect of road networks on species with decreasing populations was large. We conclude that unpaved and sporadically used roads can have detrimental effects on the bird communities, especially on vulnerable species. We propose that actions are taken to limit the extent of road networks within protected areas, especially in sites designated for their rich avifauna, such as Pafos Forest, where several of the affected species are species of European and global importance.

  4. Multisite study of particle number concentrations in urban air.

    PubMed

    Harrison, Roy M; Jones, Alan M

    2005-08-15

    Particle number concentration data are reported from a total of eight urban site locations in the United Kingdom. Of these, six are central urban background sites, while one is an urban street canyon (Marylebone Road) and another is influenced by both a motorway and a steelworks (Port Talbot). The concentrations are generally of a similar order to those reported in the literature, although higher than those in some of the other studies. Highest concentrations are at the Marylebone Road site and lowest are at the Port Talbot site. The central urban background locations lie somewhere between with concentrations typically around 20 000 cm(-3). A seasonal pattern affects all sites, with highest concentrations in the winter months and lowest concentrations in the summer. Data from all sites show a diurnal variation with a morning rush hour peak typical of an anthropogenic pollutant. When the dilution effects of windspeed are accounted for, the data show little directionality at the central urban background sites indicating the influence of sources from all directions as might be expected if the major source were road traffic. At the London Marylebone Road site there is high directionality driven by the air circulation in the street canyon, and at the Port Talbot site different diurnal patterns are seen for particle number count and PM10 influenced by emissions from road traffic (particle number count) and the steelworks (PM10) and local meteorological factors. Hourly particle number concentrations are generally only weakly correlated to NO(x) and PM10, with the former showing a slightly closer relationship. Correlations between daily average particle number count and PM10 were also weak. Episodes of high PM10 concentration in summer typically show low particle number concentrations consistent with transport of accumulation mode secondary aerosol, while winter episodes are frequently associated with high PM10 and particle number count arising from poor dispersion of local primary emissions.

  5. 76 FR 30907 - Proposed Foreign-Trade Zone-Eloy, AZ; Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ... Toltec Road, Eloy; and, proposed Site 4 (293 acres)--Red Rock Industrial Park, located along Interstate 10 and the Union Pacific Railroad line opposite Sasco Road, Red Rock. The sites are owned by the City... Executive Secretary, Foreign-Trade Zones Board, Room 2111, U.S. Department of Commerce, 1401 Constitution...

  6. Characterization of a medium-sized washer-gun for an axisymmetric mirror

    NASA Astrophysics Data System (ADS)

    Yi, Hongshen; Liu, Ming; Shi, Peiyun; Yang, Zhida; Zhu, Guanghui; Lu, Quanming; Sun, Xuan

    2018-04-01

    A new medium-sized washer gun is developed for a plasma start-up in a fully axisymmetric mirror. The gun is positioned at the east end of the Keda Mirror with AXisymmetricity facility and operated in the pulsed mode with an arc discharging time of 1.2 ms and a typical arc current of 8.5 kA with 1.5 kV discharge voltage. To optimize the operation, a systematic scan of the neutral pressure, the arc voltage, the bias voltage on a mesh grid 6 cm in front of the gun and an end electrode located on the west end of mirror, and the mirror ratio was performed. The streaming plasma was measured with triple probes in the three mirror cells and a diamagnetic loop in the central cell. Floating potential measurements suggest that the plasma could be divided into streaming and mirror-confined plasmas. The floating potential for the streaming plasma is negative, with an electric field pointing inwards. The mirror-confined plasma has a typical lifetime of 0.5 ms.

  7. Characterization of a medium-sized washer-gun for an axisymmetric mirror.

    PubMed

    Yi, Hongshen; Liu, Ming; Shi, Peiyun; Yang, Zhida; Zhu, Guanghui; Lu, Quanming; Sun, Xuan

    2018-04-01

    A new medium-sized washer gun is developed for a plasma start-up in a fully axisymmetric mirror. The gun is positioned at the east end of the Keda Mirror with AXisymmetricity facility and operated in the pulsed mode with an arc discharging time of 1.2 ms and a typical arc current of 8.5 kA with 1.5 kV discharge voltage. To optimize the operation, a systematic scan of the neutral pressure, the arc voltage, the bias voltage on a mesh grid 6 cm in front of the gun and an end electrode located on the west end of mirror, and the mirror ratio was performed. The streaming plasma was measured with triple probes in the three mirror cells and a diamagnetic loop in the central cell. Floating potential measurements suggest that the plasma could be divided into streaming and mirror-confined plasmas. The floating potential for the streaming plasma is negative, with an electric field pointing inwards. The mirror-confined plasma has a typical lifetime of 0.5 ms.

  8. Erosion on logging roads in northwestern California: How much is avoidable?

    Treesearch

    John D. McCashion; Raymond M. Rice

    1983-01-01

    Abstract - A study was made on 344 miles of logging roads in northwestern California to assess sources of erosion and the extent to which road-related erosion is avoidable. At most, about 24 percent of the erosion measured on the logging roads could have been prevented by conventional engineering methods. The remaining 76 percent was caused by site conditions and...

  9. Comparison of the predictions of two road dust emission models with the measurements of a mobile van

    NASA Astrophysics Data System (ADS)

    Kauhaniemi, M.; Stojiljkovic, A.; Pirjola, L.; Karppinen, A.; Härkönen, J.; Kupiainen, K.; Kangas, L.; Aarnio, M. A.; Omstedt, G.; Denby, B. R.; Kukkonen, J.

    2014-02-01

    The predictions of two road dust suspension emission models were compared with the on-site mobile measurements of suspension emission factors. Such a quantitative comparison has not previously been reported in the reviewed literature. The models used were the Nordic collaboration model NORTRIP (NOn-exhaust Road TRaffic Induced Particle emissions) and the Swedish-Finnish FORE model (Forecasting Of Road dust Emissions). These models describe particulate matter generated by the wear of road surface due to traction control methods and processes that control the suspension of road dust particles into the air. An experimental measurement campaign was conducted using a mobile laboratory called SNIFFER, along two selected road segments in central Helsinki in 2007 and 2008. The suspended PM10 concentration was measured behind the left rear tyre and the street background PM10 concentration in front of the van. Both models reproduced the measured seasonal variation of suspension emission factors fairly well during both years at both measurement sites. However, both models substantially under-predicted the measured emission values. The results indicate that road dust emission models can be directly compared with mobile measurements; however, more extensive and versatile measurement campaigns will be needed in the future.

  10. To BG or not to BG: Background Subtraction for EIT Coronal Loops

    NASA Astrophysics Data System (ADS)

    Beene, J. E.; Schmelz, J. T.

    2003-05-01

    One of the few observational tests for various coronal heating models is to determine the temperature profile along coronal loops. Since loops are such an abundant coronal feature, this method originally seemed quite promising - that the coronal heating problem might actually be solved by determining the temperature as a function of arc length and comparing these observations with predictions made by different models. But there are many instruments currently available to study loops, as well as various techniques used to determine their temperature characteristics. Consequently, there are many different, mostly conflicting temperature results. We chose data for ten coronal loops observed with the Extreme ultraviolet Imaging Telescope (EIT), and chose specific pixels along each loop, as well as corresponding nearby background pixels where the loop emission was not present. Temperature analysis from the 171-to-195 and 195-to-284 angstrom image ratios was then performed on three forms of the data: the original data alone, the original data with a uniform background subtraction, and the original data with a pixel-by-pixel background subtraction. The original results show loops of constant temperature, as other authors have found before us, but the 171-to-195 and 195-to-284 results are significantly different. Background subtraction does not change the constant-temperature result or the value of the temperature itself. This does not mean that loops are isothermal, however, because the background pixels, which are not part of any contiguous structure, also produce a constant-temperature result with the same value as the loop pixels. These results indicate that EIT temperature analysis should not be trusted, and the isothermal loops that result from EIT (and TRACE) analysis may be an artifact of the analysis process. Solar physics research at the University of Memphis is supported by NASA grants NAG5-9783 and NAG5-12096.

  11. EUV Waves Driven by the Sudden Expansion of Transequatorial Loops Caused by Coronal Jets

    NASA Astrophysics Data System (ADS)

    Shen, Yuandeng; Tang, Zehao; Miao, Yuhu; Su, Jiangtao; Liu, Yu

    2018-06-01

    We present two events to study the driving mechanism of extreme-ultraviolet (EUV) waves that are not associated with coronal mass ejections (CMEs), by using high-resolution observations taken by the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory. Observational results indicate that the observed EUV waves were accompanied by flares and coronal jets, but not the CMEs that were regarded as drivers of most EUV waves in previous studies. In the first case, it is observed that a coronal jet is ejected along a transequatorial loop system at a plane-of-the-sky (POS) speed of 335 ± 22 km s{}-1; in the meantime, an arc-shaped EUV wave appeared on the eastern side of the loop system. In addition, the EUV wave further interacted with another interconnecting loop system and launched a fast propagating (QFP) magnetosonic wave along the loop system, which had a period of 200 s and a speed of 388 ± 65 km s{}-1, respectively. In the second case, we observed a coronal jet that ejected at a POS speed of 282 ± 44 km s{}-1 along a transequatorial loop system as well as the generation of bright EUV waves on the eastern side of the loop system. Based on the observational results, we propose that the observed EUV waves on the eastern side of the transequatorial loop systems are fast-mode magnetosonic waves and that they are driven by the sudden lateral expansion of the transequatorial loop systems due to the direct impingement of the associated coronal jets, while the QFP wave in the fist case formed due to the dispersive evolution of the disturbance caused by the interaction between the EUV wave and the interconnecting coronal loops. It is noted that EUV waves driven by sudden loop expansions have shorter lifetimes than those driven by CMEs.

  12. Comparison of the predictions of two road dust emission models with the measurements of a mobile van

    NASA Astrophysics Data System (ADS)

    Kauhaniemi, M.; Stojiljkovic, A.; Pirjola, L.; Karppinen, A.; Härkönen, J.; Kupiainen, K.; Kangas, L.; Aarnio, M. A.; Omstedt, G.; Denby, B. R.; Kukkonen, J.

    2014-09-01

    The predictions of two road dust suspension emission models were compared with the on-site mobile measurements of suspension emission factors. Such a quantitative comparison has not previously been reported in the reviewed literature. The models used were the Nordic collaboration model NORTRIP (NOn-exhaust Road TRaffic Induced Particle emissions) and the Swedish-Finnish FORE model (Forecasting Of Road dust Emissions). These models describe particulate matter generated by the wear of road surface due to traction control methods and processes that control the suspension of road dust particles into the air. An experimental measurement campaign was conducted using a mobile laboratory called SNIFFER, along two selected road segments in central Helsinki in 2007 and 2008. The suspended PM10 concentration was measured behind the left rear tyre and the street background PM10 concentration in front of the van. Both models reproduced the measured seasonal variation of suspension emission factors fairly well during both years at both measurement sites. However, both models substantially under-predicted the measured emission values. The article illustrates the challenges in conducting road suspension measurements in densely trafficked urban conditions, and the numerous requirements for input data that are needed for accurately applying road suspension emission models.

  13. Molecular insights into the mechanism of thermal stability of actinomycete mannanase.

    PubMed

    Kumagai, Yuya; Uraji, Misugi; Wan, Kun; Okuyama, Masayuki; Kimura, Atsuo; Hatanaka, Tadashi

    2016-09-01

    Streptomyces thermolilacinus mannanase (StMan), which requires Ca(2+) for its enhanced thermal stability and hydrolysis activity, possesses two Ca(2+) -binding sites in loop6 and loop7. We evaluated the function of the Ca(2+) -binding site in loop7 and the hydrogen bond between residues Ser247 in loop6 and Asp279 in loop7. The Ca(2+) -binding in loop7 was involved only in thermal stability. Mutations of Ser247 or Asp279 retained the Ca(2+) -binding ability; however, mutants showed less thermal stability than StMan. Phylogenetic analysis indicated that most glycoside hydrolase family 5 subfamily 8 mannanases could be stabilized by Ca(2+) ; however, the mechanism of StMan thermal stability was found to be quite specific in some actinomycete mannanases. © 2016 Federation of European Biochemical Societies.

  14. Diversity and Petrogenesis of <4.4 Ma Rhyolites from the Izu Bonin Rear-Arc

    NASA Astrophysics Data System (ADS)

    Heywood, L. J.; DeBari, S. M.; Schindlbeck, J. C.; Escobar-Burciaga, R. D.; Gill, J.

    2016-12-01

    The Izu Bonin subduction zone has a history of abundant rhyolite production that is relevant to the development of intermediate to silicic middle crust. This study presents major and trace elemental compositions (via electron microprobe and LA-ICP-MS) of unaltered volcanic glass and phenocrysts from select medium- to high-K tephra intervals from IODP Site 1437 (Expedition 350, Izu Bonin Rear Arc). These data provide a time-resolved record of regional explosive magmatism ( 4.4Ma to present). Tephra from Site 1437 is basaltic to rhyolitic glass with accompanying phenocrysts, including hornblende. Glass compositions form a medium-K magmatic series with LREE enrichment (LaN/YbN = 2.5-6) whose trace element ratios and isotopic compositions are distinct from magmas with similar SiO2 contents in the main Izu Bonin volcanic front. Other workers have shown progressive enrichment in K and other trace element ratios moving from volcanic front westwards through the extensional region to the western seamounts in the rear arc. The <4.4 Ma rear-arc rhyolites from Site 1437 show pronounced negative Eu anomalies, high LaN/SmN (2-3.5), Ba/La <25 and Th of 1.5-4 ppm. These rhyolites show the highest variability for a given SiO2 content among all rear-arc magmas (rhyolites have 1.5-3.5 wt% K2O, Zr/Y of 1-8, LaN of 5-9 ppm) consistent with variability in literature reports of other rhyolite samples dredged from surrounding seamounts. Rhyolites have been dredged from several nearby seamounts with other high-K rhyolites dredged as close as nearby Meireki Seamount ( 3.8 Ma) and further afield in the Genroku seamount chain ( 1.88 Ma), which we compare to Site 1437 rhyolites. An extremely low-K rhyolite sill (13.6 Ma) was drilled lower in the section at Site U1437, suggesting that the mechanism for producing rhyolites in the Western Seamounts region changed over time. Rhyolites are either produced by differentiation of mafic magmas, by melting of pre-existing arc crust (as hypothesized in the Izu Bonin volcanic front), or through a combination of various processes. Because the oldest rear-arc rhyolites are low-K with limited LREE enrichment, any scenario that requires melting of pre-existing crust to produce the 4.4 Ma high-K rhyolites would require a crustal source that is younger than 13.6 Ma.

  15. Modeling, simulation and control of pulsed DE-GMA welding process for joining of aluminum to steel

    NASA Astrophysics Data System (ADS)

    Zhang, Gang; Shi, Yu; Li, Jie; Huang, Jiankang; Fan, Ding

    2014-09-01

    Joining of aluminum to steel has attracted significant attention from the welding research community, automotive and rail transportation industries. Many current welding methods have been developed and applied, however, they can not precisely control the heat input to work-piece, they are high costs, low efficiency and consist lots of complex welding devices, and the generated intermetallic compound layer in weld bead interface is thicker. A novel pulsed double electrode gas metal arc welding(Pulsed DE-GMAW) method is developed. To achieve a stable welding process for joining of aluminum to steel, a mathematical model of coupled arc is established, and a new control scheme that uses the average feedback arc voltage of main loop to adjust the wire feed speed to control coupled arc length is proposed and developed. Then, the impulse control simulation of coupled arc length, wire feed speed and wire extension is conducted to demonstrate the mathematical model and predict the stability of welding process by changing the distance of contact tip to work-piece(CTWD). To prove the proposed PSO based PID control scheme's feasibility, the rapid prototyping experimental system is setup and the bead-on-plate control experiments are conducted to join aluminum to steel. The impulse control simulation shows that the established model can accurately represent the variation of coupled arc length, wire feed speed and the average main arc voltage when the welding process is disturbed, and the developed controller has a faster response and adjustment, only runs about 0.1 s. The captured electric signals show the main arc voltage gradually closes to the supposed arc voltage by adjusting the wire feed speed in 0.8 s. The obtained typical current waveform demonstrates that the main current can be reduced by controlling the bypass current under maintaining a relative large total current. The control experiment proves the accuracy of proposed model and feasibility of new control scheme further. The beautiful and smooth weld beads are also obtained by this method. Pulsed DE-GMAW can thus be considered as an alternative method for low cost, high efficiency joining of aluminum to steel.

  16. A Conserved Surface Loop in Type I Dehydroquinate Dehydratases Positions an Active Site Arginine and Functions in Substrate Binding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Light, Samuel H.; Minasov, George; Shuvalova, Ludmilla

    2012-04-18

    Dehydroquinate dehydratase (DHQD) catalyzes the third step in the biosynthetic shikimate pathway. We present three crystal structures of the Salmonella enterica type I DHQD that address the functionality of a surface loop that is observed to close over the active site following substrate binding. Two wild-type structures with differing loop conformations and kinetic and structural studies of a mutant provide evidence of both direct and indirect mechanisms of involvement of the loop in substrate binding. In addition to allowing amino acid side chains to establish a direct interaction with the substrate, closure of the loop necessitates a conformational change ofmore » a key active site arginine, which in turn positions the substrate productively. The absence of DHQD in humans and its essentiality in many pathogenic bacteria make the enzyme a target for the development of nontoxic antimicrobials. The structures and ligand binding insights presented here may inform the design of novel type I DHQD inhibiting molecules.« less

  17. Geologic road guides for the Southern Canadian Cordillera--Viewing geology and tectonics along major highways

    USGS Publications Warehouse

    Nokleberg, Warren J.; Price, Raymond A.; Bundtzen, Thomas K.; Nokleberg, Warren J.; Price, Raymond A.; Scholl, David W.; Stone, David B.

    2017-01-01

    The Geologic Road Guides for the Southern Canadian Cordillera provide a layperson’s understanding of the major geologic units and their tectonic origins along portions of two sets of major highways corridors, herein termed the Southern Road Guide and the Northern Road Guide. The two routes are shown on the Southern Canadian Cordillera Geologic Map. The first page of each Road Guide is this map that has Hot Spots for each site.

  18. The impact of closed-loop electronic medication management on time to first dose: a comparative study between paper and digital hospital environments.

    PubMed

    Austin, Jodie A; Smith, Ian R; Tariq, Amina

    2018-01-22

    Closed-loop electronic medication management systems (EMMS) are recognised as an effective intervention to improve medication safety, yet evidence of their effectiveness in hospitals is limited. Few studies have compared medication turnaround time for a closed-loop electronic versus paper-based medication management environment. To compare medication turnaround times in a paper-based hospital environment with a digital hospital equipped with a closed-loop EMMS, consisting of computerised physician order entry, profiled automated dispensing cabinets packaged with unit dose medications and barcode medication administration. Data were collected during 2 weeks at three private hospital sites (one with closed-loop EMMS) within the same organisation network in Queensland, Australia. Time between scheduled and actual administration times was analysed for first dose of time-critical and non-critical medications located on the ward or sourced via pharmacy. Medication turnaround times at the EMMS site were less compared to the paper-based sites (median, IQR: 35 min, 8-57 min versus 120 min, 30-180 min, P < 0.001). For time-critical medications, 77% were administered within 60 min of scheduled time at the EMMS site versus 38% for the paper-based sites. Similar difference was observed for non-critical medications, 80% were administered within 60 min of their scheduled time at the EMMS site versus 41% at the paper-based facilities. The study indicates medication turnaround times utilising a closed-loop EMMS are less compared to paper-based systems. This improvement may be attributable to increased accessibility of medications using automated dispensing cabinets and electronic medication administration records flagging tasks to nurses in real time. © 2018 Royal Pharmaceutical Society.

  19. Understanding Which Residues of the Active Site and Loop Structure of a Tyrosine Aminomutase Define Its Mutase and Lyase Activities.

    PubMed

    Attanayake, Gayanthi; Walter, Tyler; Walker, Kevin D

    2018-05-30

    Site-directed mutations and substrate analogues were used to gain insights into the branch-point reaction of the 3,5-dihydro-5-methylidene-4 H-imidazol-4-one (MIO)-tyrosine aminomutase from Oryza sativa ( OsTAM). Exchanging the active residues of OsTAM (Y125C/N446K) for those in a phenylalanine aminomutase TcPAM altered its substrate specificity from tyrosine to phenylalanine. The aminomutase mechanism of OsTAM surprisingly changed almost exclusively to that of an ammonia lyase making cinnamic acid (>95%) over β-phenylalanine [Walter, T., et al. (2016) Biochemistry 55, 3497-3503]. We hypothesized that the missing electronics or sterics on the aryl ring of the phenylalanine substrate, compared with the sizable electron-donating hydroxyl of the natural tyrosine substrate, influenced the unexpected lyase reactivity of the OsTAM mutant. The double mutant was incubated with 16 α-phenylalanine substituent analogues of varying electronic strengths and sterics. The mutant converted each analogue principally to its acrylate with ∼50% conversion of the p-Br substrate, making only a small amount of the β-amino acid. The inner loop structure over the entrance to the active site was also mutated to assess how the lyase and mutase activities are affected. An OsTAM loop mutant, matching the loop residues of TcPAM, still chiefly made >95% of the acrylate from each substrate. A combined active site:loop mutant was most reactive but remained a lyase, making 10-fold more acrylates than other mutants did. While mutations within the active site changed the substrate specificity of OsTAM, continued exploration is needed to fully understand the interplay among the inner loop, the substrate, and the active site in defining the mutase and lyase activities.

  20. Rock art at the 'Mini-Yengo' site near Kulnura, New South Wales

    NASA Astrophysics Data System (ADS)

    Hamacher, Duane W.; Clegg, John K.; Pankhurst, Robert S.

    2012-11-01

    The "Mini-Yengo" rock art site is located in Mangrove Creek Dam Park on Kyola Road, near the corner of Kyola Road and George Downes Drive, approximately 1.8 km to the northwest of Kulnura, New South Wales, Australia. No records of this site were identified in the published literature (Sim 1966; Needham 1981; McCarthy 1983; Gordon 1993; McDonald 1993) but it was included in site card 45-3-0528 from the Aboriginal Heritage Information Management System (AHIMS). The site card contained unpublished surveys by V. Attenbrow in 1980 and I.M. Sim in 1976.

  1. Automated management for pavement inspection system (AMPIS)

    NASA Astrophysics Data System (ADS)

    Chung, Hung Chi; Girardello, Roberto; Soeller, Tony; Shinozuka, Masanobu

    2003-08-01

    An automated in-situ road surface distress surveying and management system, AMPIS, has been developed on the basis of video images within the framework of GIS software. Video image processing techniques are introduced to acquire, process and analyze the road surface images obtained from a moving vehicle. ArcGIS platform is used to integrate the routines of image processing and spatial analysis in handling the full-scale metropolitan highway surface distress detection and data fusion/management. This makes it possible to present user-friendly interfaces in GIS and to provide efficient visualizations of surveyed results not only for the use of transportation engineers to manage road surveying documentations, data acquisition, analysis and management, but also for financial officials to plan maintenance and repair programs and further evaluate the socio-economic impacts of highway degradation and deterioration. A review performed in this study on fundamental principle of Pavement Management System (PMS) and its implementation indicates that the proposed approach of using GIS concept and its tools for PMS application will reshape PMS into a new information technology-based system providing a convenient and efficient pavement inspection and management.

  2. GIS-based automated management of highway surface crack inspection system

    NASA Astrophysics Data System (ADS)

    Chung, Hung-Chi; Shinozuka, Masanobu; Soeller, Tony; Girardello, Roberto

    2004-07-01

    An automated in-situ road surface distress surveying and management system, AMPIS, has been developed on the basis of video images within the framework of GIS software. Video image processing techniques are introduced to acquire, process and analyze the road surface images obtained from a moving vehicle. ArcGIS platform is used to integrate the routines of image processing and spatial analysis in handling the full-scale metropolitan highway surface distress detection and data fusion/management. This makes it possible to present user-friendly interfaces in GIS and to provide efficient visualizations of surveyed results not only for the use of transportation engineers to manage road surveying documentations, data acquisition, analysis and management, but also for financial officials to plan maintenance and repair programs and further evaluate the socio-economic impacts of highway degradation and deterioration. A review performed in this study on fundamental principle of Pavement Management System (PMS) and its implementation indicates that the proposed approach of using GIS concept and its tools for PMS application will reshape PMS into a new information technology-based system that can provide convenient and efficient pavement inspection and management.

  3. Chain-Wise Generalization of Road Networks Using Model Selection

    NASA Astrophysics Data System (ADS)

    Bulatov, D.; Wenzel, S.; Häufel, G.; Meidow, J.

    2017-05-01

    Streets are essential entities of urban terrain and their automatized extraction from airborne sensor data is cumbersome because of a complex interplay of geometric, topological and semantic aspects. Given a binary image, representing the road class, centerlines of road segments are extracted by means of skeletonization. The focus of this paper lies in a well-reasoned representation of these segments by means of geometric primitives, such as straight line segments as well as circle and ellipse arcs. We propose the fusion of raw segments based on similarity criteria; the output of this process are the so-called chains which better match to the intuitive perception of what a street is. Further, we propose a two-step approach for chain-wise generalization. First, the chain is pre-segmented using circlePeucker and finally, model selection is used to decide whether two neighboring segments should be fused to a new geometric entity. Thereby, we consider both variance-covariance analysis of residuals and model complexity. The results on a complex data-set with many traffic roundabouts indicate the benefits of the proposed procedure.

  4. The Natively Disordered Loop of Bcl-2 Undergoes Phosphorylation-Dependent Conformational Change and Interacts with Pin1

    PubMed Central

    Kang, CongBao; Bharatham, Nagakumar; Chia, Joel; Mu, Yuguang; Baek, Kwanghee; Yoon, Ho Sup

    2012-01-01

    Bcl-2 plays a central role in the regulation of apoptosis. Structural studies of Bcl-2 revealed the presence of a flexible and natively disordered loop that bridges the Bcl-2 homology motifs, BH3 and BH4. This loop is phosphorylated on multiple sites in response to a variety of external stimuli, including the microtubule-targeting drugs, paclitaxel and colchicine. Currently, the underlying molecular mechanism of Bcl-2 phosphorylation and its biological significance remain elusive. In this study, we investigated the molecular characteristics of this anti-apoptotic protein. To this end, we generated synthetic peptides derived from the Bcl-2 loop, and multiple Bcl-2 loop truncation mutants that include the phosphorylation sites. Our results demonstrate that S87 in the flexible loop of Bcl-2 is the primary phosphorylation site for JNK and ERK2, suggesting some sequence or structural specificity for the phosphorylation by these kinases. Our NMR studies and molecular dynamics simulation studies support indicate that phosphorylation of S87 induces a conformational change in the peptide. Finally, we show that the phosphorylated peptides of the Bcl-2 loop can bind Pin1, further substantiating the phosphorylation-mediated conformation change of Bcl-2. PMID:23272207

  5. Positional accuracy and geographic bias of four methods of geocoding in epidemiologic research.

    PubMed

    Schootman, Mario; Sterling, David A; Struthers, James; Yan, Yan; Laboube, Ted; Emo, Brett; Higgs, Gary

    2007-06-01

    We examined the geographic bias of four methods of geocoding addresses using ArcGIS, commercial firm, SAS/GIS, and aerial photography. We compared "point-in-polygon" (ArcGIS, commercial firm, and aerial photography) and the "look-up table" method (SAS/GIS) to allocate addresses to census geography, particularly as it relates to census-based poverty rates. We randomly selected 299 addresses of children treated for asthma at an urban emergency department (1999-2001). The coordinates of the building address side door were obtained by constant offset based on ArcGIS and a commercial firm and true ground location based on aerial photography. Coordinates were available for 261 addresses across all methods. For 24% to 30% of geocoded road/door coordinates the positional error was 51 meters or greater, which was similar across geocoding methods. The mean bearing was -26.8 degrees for the vector of coordinates based on aerial photography and ArcGIS and 8.5 degrees for the vector based on aerial photography and the commercial firm (p < 0.0001). ArcGIS and the commercial firm performed very well relative to SAS/GIS in terms of allocation to census geography. For 20%, the door location based on aerial photography was assigned to a different block group compared to SAS/GIS. The block group poverty rate varied at least two standard deviations for 6% to 7% of addresses. We found important differences in distance and bearing between geocoding relative to aerial photography. Allocation of locations based on aerial photography to census-based geographic areas could lead to substantial errors.

  6. The Role of Water Vapor and Dissociative Recombination Processes in Solar Array Arc Initiation

    NASA Technical Reports Server (NTRS)

    Galofar, J.; Vayner, B.; Degroot, W.; Ferguson, D.

    2002-01-01

    Experimental plasma arc investigations involving the onset of arc initiation for a negatively biased solar array immersed in low-density plasma have been performed. Previous studies into the arc initiation process have shown that the most probable arcing sites tend to occur at the triple junction involving the conductor, dielectric and plasma. More recently our own experiments have led us to believe that water vapor is the main causal factor behind the arc initiation process. Assuming the main component of the expelled plasma cloud by weight is water, the fastest process available is dissociative recombination (H2O(+) + e(-) (goes to) H* + OH*). A model that agrees with the observed dependency of arc current pulse width on the square root of capacitance is presented. A 400 MHz digital storage scope and current probe was used to detect arcs at the triple junction of a solar array. Simultaneous measurements of the arc trigger pulse, the gate pulse, the arc current and the arc voltage were then obtained. Finally, a large number of measurements of individual arc spectra were obtained in very short time intervals, ranging from 10 to 30 microseconds, using a 1/4 a spectrometer coupled with a gated intensified CCD. The spectrometer was systematically tuned to obtain optical arc spectra over the entire wavelength range of 260 to 680 nanometers. All relevant atomic lines and molecular bands were then identified.

  7. Characteristics of Urbanization in Five Watersheds of Anchorage, Alaska: Geographic Information System Data

    USGS Publications Warehouse

    Moran, Edward H.

    2002-01-01

    The report contains environmental and urban geographic information system data for 14 sites in 5 watersheds in Anchorage, Alaska. These sites were examined during summer in 1999 and 2000 to determine effects of urbanization on water quality. The data sets are Environmental Systems Research Institute, Inc., shapefiles, coverages, and images. Also included are an elevation grid and a triangulated irregular network. Although the data are intended for users with advanced geographic information system capabilities, simple images of the data also are available. ArcView? 3.2 project, an ArcGIS? project, and 16 ArcExplorer2? projects are linked to the PDF file based report. Some of these coverages are large files over 10 MB. The largest coverage, impervious cover, is 208 MB.

  8. Robust control of drag and lateral dynamic response for road vehicles exposed to cross-wind gusts

    NASA Astrophysics Data System (ADS)

    Pfeiffer, Jens; King, Rudibert

    2018-03-01

    A robust closed-loop active flow control strategy for road vehicles under unsteady cross-wind conditions is presented. It is designed based on black-box models identified from experimental data for a 3D bluff body equipped with Coanda actuators along the rear edges. The controller adjusts the blowing rates of the actuators individually, achieving a drag reduction of about 15% while simultaneously improving cross-wind sensitivity. Hereby, the lateral vehicle dynamics and driver behavior are taken into account and replicated in the wind tunnel via a novel model support system. The effectiveness of the control strategy is demonstrated via cross-wind gust experiments.

  9. An ABS control logic based on wheel force measurement

    NASA Astrophysics Data System (ADS)

    Capra, D.; Galvagno, E.; Ondrak, V.; van Leeuwen, B.; Vigliani, A.

    2012-12-01

    The paper presents an anti-lock braking system (ABS) control logic based on the measurement of the longitudinal forces at the hub bearings. The availability of force information allows to design a logic that does not rely on the estimation of the tyre-road friction coefficient, since it continuously tries to exploit the maximum longitudinal tyre force. The logic is designed by means of computer simulation and then tested on a specific hardware in the loop test bench: the experimental results confirm that measured wheel force can lead to a significant improvement of the ABS performances in terms of stopping distance also in the presence of road with variable friction coefficient.

  10. Hypothesis-driven and field-validated method to prioritize fragmentation mitigation efforts in road projects.

    PubMed

    Vanthomme, Hadrien; Kolowski, Joseph; Nzamba, Brave S; Alonso, Alfonso

    2015-10-01

    The active field of connectivity conservation has provided numerous methods to identify wildlife corridors with the aim of reducing the ecological effect of fragmentation. Nevertheless, these methods often rely on untested hypotheses of animal movements, usually fail to generate fine-scale predictions of road crossing sites, and do not allow managers to prioritize crossing sites for implementing road fragmentation mitigation measures. We propose a new method that addresses these limitations. We illustrate this method with data from southwestern Gabon (central Africa). We used stratified random transect surveys conducted in two seasons to model the distribution of African forest elephant (Loxodonta cyclotis), forest buffalo (Syncerus caffer nanus), and sitatunga (Tragelaphus spekii) in a mosaic landscape along a 38.5 km unpaved road scheduled for paving. Using a validation data set of recorded crossing locations, we evaluated the performance of three types of models (local suitability, local least-cost movement, and regional least-cost movement) in predicting actual road crossings for each species, and developed a unique and flexible scoring method for prioritizing road sections for the implementation of road fragmentation mitigation measures. With a data set collected in <10 weeks of fieldwork, the method was able to identify seasonal changes in animal movements for buffalo and sitatunga that shift from a local exploitation of the site in the wet season to movements through the study site in the dry season, whereas elephants use the entire study area in both seasons. These three species highlighted the need to use species- and season-specific modeling of movement. From these movement models, the method ranked road sections for their suitability for implementing fragmentation mitigation efforts, allowing managers to adjust priority thresholds based on budgets and management goals. The method relies on data that can be obtained in a period compatible with environmental impact assessment constraints, and is flexible enough to incorporate other potential movement models and scoring criteria. This approach improves upon available methods and can help inform prioritization of road and other linear infrastructure segments that require impact mitigation methods to ensure long-term landscape connectivity.

  11. Snow Roads at McMurdo Station, Antarctica

    DTIC Science & Technology

    2010-05-01

    is minimized distribution of low strength areas (also called “ holidays ”). Holidays are actually areas of pulverized snow that are missed or inade...quately processed. Though holidays usually occur sporadically, any single flaw may extend through the entire thickness of an unelevated road. The...Pegasus Road and the LDB pad. A few additional sites were chosen for comparison (Williams Field, virgin snow, etc.). Williams Field Road densities

  12. 36 CFR 71.3 - Designation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...: Tent or trailer spaces, drinking water, access road, refuse containers, toilet facilities, personal fee..., roads, overlook sites, visitors' centers, scenic drives, toilet facilities, picnic tables, and boat...

  13. 36 CFR 71.3 - Designation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...: Tent or trailer spaces, drinking water, access road, refuse containers, toilet facilities, personal fee..., roads, overlook sites, visitors' centers, scenic drives, toilet facilities, picnic tables, and boat...

  14. 36 CFR 71.3 - Designation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...: Tent or trailer spaces, drinking water, access road, refuse containers, toilet facilities, personal fee..., roads, overlook sites, visitors' centers, scenic drives, toilet facilities, picnic tables, and boat...

  15. SU-F-T-558: ArcCheck for Patient Specific QA in Stereotactic Ablative Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ramachandran, P; RMIT University, Bundoora; Tajaldeen, A

    2016-06-15

    Purpose: Stereotactic Ablative Radiotherapy (SABR) is one of the most preferred treatment techniques for early stage lung cancer. This technique has been extended to other treatment sites like Spine, Liver, Scapula, Sternum etc., This has resulted in increased physics QA time on machine. In this study, we’ve tested the feasibility of using ArcCheck as an alternative method to replace film dosimetry. Methods: Twelve patients with varied diagnosis of Lung, Liver, scapula, sternum and Spine undergoing SABR were selected for this study. Pre-treatment QA was performed for all the patients which include ionization chamber and film dosimetry. The required gamma criteriamore » for each SABR plan to pass QA and proceed to treatment is 95% (3%,1mm). In addition to this routine process, the treatment plans were exported on to an ArcCheck phantom. The planned and measured dose from the ArcCheck device were compared using four different gamma criteria: 2%,2 mm, 3%,2 mm, 3%,1 mm and 3%, 3 mm. In addition to this, we’ve also introduced errors to gantry, collimator and couch angle to assess sensitivity of the ArcCheck with potential delivery errors. Results: The ArcCheck mean passing rates for all twelve cases were 76.1%±9.7% for gamma criteria 3%,1 mm, 89.5%±5.3% for 2%,2 mm, 92.6%±4.2% for 3%,2 mm, and 97.6%±2.4% for 3%,3 mm gamma criteria. When SABR spine cases are excluded, we observe ArcCheck passing rates higher than 95% for all the studied cases with 3%, 3mm, and ArcCheck results in acceptable agreement with the film gamma results. Conclusion: Our ArcCheck results at 3%, 3 mm were found to correlate well with our non-SABR spine routine patient specific QA results (3%,1 mm). We observed significant reduction in QA time on using ArcCheck for SABR QA. This study shows that ArcCheck could replace film dosimetry for all sites except SABR spine.« less

  16. 76 FR 50717 - Foreign-Trade Zone 74, Baltimore, MD; Application for Reorganization/Expansion Under Alternative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-16

    ... 28 (2.5 acres)-- McCormick & Company, Inc., 11102 McCormick Road, Hunt Valley (Baltimore County); Proposed Site 29 (17.6 acres)--McCormick & Company, Inc., 10901 Gilroy Road, Hunt Valley (Baltimore County); and, Proposed Site 30 (8.48 acres)--McCormick & Company, Inc., 4607 Appliance Drive, Belcamp (Harford...

  17. Erosion at decommissioned road-stream crossings: case studies from three northern California watersheds

    Treesearch

    Sam A. Flanagan; David Fuller; Leonard Job; Sam Morrison

    2012-01-01

    Post-treatment erosion was observed for 41 decommissioned road stream crossings in three northern California watersheds. Sites were purposefully selected in order to characterize the nature and range of post-treatment erosional responses. Sites with the highest visible erosion were selected in order to better understand the dominant process and incorporate any...

  18. Taking Your Show on the Road.

    ERIC Educational Resources Information Center

    Buchanan, Suzanne

    1998-01-01

    Describes a local interpretation program in New England that uses a motorcoach to take visitors on a day-long tour of several sites in the region. Explains how to create similar programs elsewhere and gives advice for preparing for the tour, orienting tour members, interpreting on the road, pacing tours over a day, and stopping at tour sites. (PVD)

  19. Salamander abundance along road edges and within abandoned logging roads in Appalachian forests.

    PubMed

    Semlitsch, Raymond D; Ryan, Travis J; Hamed, Kevin; Chatfield, Matt; Drehman, Bethany; Pekarek, Nicole; Spath, Mike; Watland, Angie

    2007-02-01

    Roads may be one of the most common disturbances in otherwise continuous forested habitat in the southern Appalachian Mountains. Despite their obvious presence on the landscape, there is limited data on the ecological effects along a road edge or the size of the "road-effect zone." We sampled salamanders at current and abandoned road sites within the Nantahala National Forest, North Carolina (U.S.A.) to determine the road-effect zone for an assemblage of woodland salamanders. Salamander abundance near the road was reduced significantly, and salamanders along the edges were predominantly large individuals. These results indicate that the road-effect zone for these salamanders extended 35 m on either side of the relatively narrow, low-use forest roads along which we sampled. Furthermore, salamander abundance was significantly lower on old, abandoned logging roads compared with the adjacent upslope sites. These results indicate that forest roads and abandoned logging roads have negative effects on forest-dependent species such as plethodontid salamanders. Our results may apply to other protected forests in the southern Appalachians and may exemplify a problem created by current and past land use activities in all forested regions, especially those related to road building for natural-resource extraction. Our results show that the effect of roads reached well beyond their boundary and that abandonment or the decommissioning of roads did not reverse detrimental ecological effects; rather, our results indicate that management decisions have significant repercussions for generations to come. Furthermore, the quantity of suitable forested habitat in the protected areas we studied was significantly reduced: between 28.6% and 36.9% of the area was affected by roads. Management and policy decisions must use current and historical data on land use to understand cumulative impacts on forest-dependent species and to fully protect biodiversity on national lands.

  20. Activation of Latent Dihydroorotase from Aquifex aeolicus by Pressure*

    PubMed Central

    Hervé, Guy; Evans, Hedeel Guy; Fernado, Roshini; Patel, Chandni; Hachem, Fatme; Evans, David R.

    2017-01-01

    Elevated hydrostatic pressure was used to probe conformational changes of Aquifex aeolicus dihydroorotase (DHO), which catalyzes the third step in de novo pyrimidine biosynthesis. The isolated protein, a 45-kDa monomer, lacks catalytic activity but becomes active upon formation of a dodecameric complex with aspartate transcarbamoylase (ATC). X-ray crystallographic studies of the isolated DHO and of the complex showed that association induces several major conformational changes in the DHO structure. In the isolated DHO, a flexible loop occludes the active site blocking the access of substrates. The loop is mostly disordered but is tethered to the active site region by several electrostatic and hydrogen bonds. This loop becomes ordered and is displaced from the active site upon formation of DHO-ATC complex. The application of pressure to the complex causes its time-dependent dissociation and the loss of both DHO and ATC activities. Pressure induced irreversible dissociation of the obligate ATC trimer, and as a consequence the DHO is also inactivated. However, moderate hydrostatic pressure applied to the isolated DHO subunit mimics the complex formation and reversibly activates the isolated subunit in the absence of ATC, suggesting that the loop has been displaced from the active site. This effect of pressure is explained by the negative volume change associated with the disruption of ionic interactions and exposure of ionized amino acids to the solvent (electrostriction). The interpretation that the loop is relocated by pressure was validated by site-directed mutagenesis and by inhibition by small peptides that mimic the loop residues. PMID:27746403

  1. 78 FR 4377 - Idaho Panhandle National Forests, Coeur d'Alene River Ranger District, Shoshone County, ID...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... organisms, and improve the longevity of road conditions by reducing maintenance costs and providing for long... storage, road reconstruction and maintenance, site preparation, reforestation, and fuel break development...); prescribed burning not associated with timber harvest; and watershed restoration (decommissioning roads...

  2. 38 CFR 39.61 - Site planning standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... roads shall be generally 24 feet wide. (4) Pavement design. The pavement section of all roads, service areas, and parking areas shall be designed for the maximum anticipated traffic loads and existing soil conditions and in accordance with local and State design criteria. (5) Curbs. Bituminous roads may be...

  3. 38 CFR 39.61 - Site planning standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... roads shall be generally 24 feet wide. (4) Pavement design. The pavement section of all roads, service areas, and parking areas shall be designed for the maximum anticipated traffic loads and existing soil conditions and in accordance with local and State design criteria. (5) Curbs. Bituminous roads may be...

  4. 38 CFR 39.61 - Site planning standards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... roads shall be generally 24 feet wide. (4) Pavement design. The pavement section of all roads, service areas, and parking areas shall be designed for the maximum anticipated traffic loads and existing soil conditions and in accordance with local and State design criteria. (5) Curbs. Bituminous roads may be...

  5. 38 CFR 39.61 - Site planning standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... roads shall be generally 24 feet wide. (4) Pavement design. The pavement section of all roads, service areas, and parking areas shall be designed for the maximum anticipated traffic loads and existing soil conditions and in accordance with local and State design criteria. (5) Curbs. Bituminous roads may be...

  6. Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase

    PubMed Central

    2012-01-01

    Background During elongation, multi-subunit RNA polymerases (RNAPs) cycle between phosphodiester bond formation and nucleic acid translocation. In the conformation associated with catalysis, the mobile “trigger loop” of the catalytic subunit closes on the nucleoside triphosphate (NTP) substrate. Closing of the trigger loop is expected to exclude water from the active site, and dehydration may contribute to catalysis and fidelity. In the absence of a NTP substrate in the active site, the trigger loop opens, which may enable translocation. Another notable structural element of the RNAP catalytic center is the “bridge helix” that separates the active site from downstream DNA. The bridge helix may participate in translocation by bending against the RNA/DNA hybrid to induce RNAP forward movement and to vacate the active site for the next NTP loading. The transition between catalytic and translocation conformations of RNAP is not evident from static crystallographic snapshots in which macromolecular motions may be restrained by crystal packing. Results All atom molecular dynamics simulations of Thermus thermophilus (Tt) RNAP reveal flexible hinges, located within the two helices at the base of the trigger loop, and two glycine hinges clustered near the N-terminal end of the bridge helix. As simulation progresses, these hinges adopt distinct conformations in the closed and open trigger loop structures. A number of residues (described as “switch” residues) trade atomic contacts (ion pairs or hydrogen bonds) in response to changes in hinge orientation. In vivo phenotypes and in vitro activities rendered by mutations in the hinge and switch residues in Saccharomyces cerevisiae (Sc) RNAP II support the importance of conformational changes predicted from simulations in catalysis and translocation. During simulation, the elongation complex with an open trigger loop spontaneously translocates forward relative to the elongation complex with a closed trigger loop. Conclusions Switching between catalytic and translocating RNAP forms involves closing and opening of the trigger loop and long-range conformational changes in the atomic contacts of amino acid side chains, some located at a considerable distance from the trigger loop and active site. Trigger loop closing appears to support chemistry and the fidelity of RNA synthesis. Trigger loop opening and limited bridge helix bending appears to promote forward nucleic acid translocation. PMID:22676913

  7. Lidar arc scan uncertainty reduction through scanning geometry optimization

    DOE PAGES

    Wang, Hui; Barthelmie, Rebecca J.; Pryor, Sara C.; ...

    2016-04-13

    Doppler lidars are frequently operated in a mode referred to as arc scans, wherein the lidar beam scans across a sector with a fixed elevation angle and the resulting measurements are used to derive an estimate of the n minute horizontal mean wind velocity (speed and direction). Previous studies have shown that the uncertainty in the measured wind speed originates from turbulent wind fluctuations and depends on the scan geometry (the arc span and the arc orientation). This paper is designed to provide guidance on optimal scan geometries for two key applications in the wind energy industry: wind turbine power performance analysis and annualmore » energy production prediction. We present a quantitative analysis of the retrieved wind speed uncertainty derived using a theoretical model with the assumption of isotropic and frozen turbulence, and observations from three sites that are onshore with flat terrain, onshore with complex terrain and offshore, respectively. The results from both the theoretical model and observations show that the uncertainty is scaled with the turbulence intensity such that the relative standard error on the 10 min mean wind speed is about 30% of the turbulence intensity. The uncertainty in both retrieved wind speeds and derived wind energy production estimates can be reduced by aligning lidar beams with the dominant wind direction, increasing the arc span and lowering the number of beams per arc scan. As a result, large arc spans should be used at sites with high turbulence intensity and/or large wind direction variation.« less

  8. Lidar arc scan uncertainty reduction through scanning geometry optimization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Hui; Barthelmie, Rebecca J.; Pryor, Sara C.

    Doppler lidars are frequently operated in a mode referred to as arc scans, wherein the lidar beam scans across a sector with a fixed elevation angle and the resulting measurements are used to derive an estimate of the n minute horizontal mean wind velocity (speed and direction). Previous studies have shown that the uncertainty in the measured wind speed originates from turbulent wind fluctuations and depends on the scan geometry (the arc span and the arc orientation). This paper is designed to provide guidance on optimal scan geometries for two key applications in the wind energy industry: wind turbine power performance analysis and annualmore » energy production prediction. We present a quantitative analysis of the retrieved wind speed uncertainty derived using a theoretical model with the assumption of isotropic and frozen turbulence, and observations from three sites that are onshore with flat terrain, onshore with complex terrain and offshore, respectively. The results from both the theoretical model and observations show that the uncertainty is scaled with the turbulence intensity such that the relative standard error on the 10 min mean wind speed is about 30% of the turbulence intensity. The uncertainty in both retrieved wind speeds and derived wind energy production estimates can be reduced by aligning lidar beams with the dominant wind direction, increasing the arc span and lowering the number of beams per arc scan. As a result, large arc spans should be used at sites with high turbulence intensity and/or large wind direction variation.« less

  9. Database of the Geology and Thermal Activity of Norris Geyser Basin, Yellowstone National Park

    USGS Publications Warehouse

    Flynn, Kathryn; Graham Wall, Brita; White, Donald E.; Hutchinson, Roderick A.; Keith, Terry E.C.; Clor, Laura; Robinson, Joel E.

    2008-01-01

    This dataset contains contacts, geologic units and map boundaries from Plate 1 of USGS Professional Paper 1456, 'The Geology and Remarkable Thermal Activity of Norris Geyser Basin, Yellowstone National Park, Wyoming.' The features are contained in the Annotation, basins_poly, contours, geology_arc, geology_poly, point_features, and stream_arc feature classes as well as a table of geologic units and their descriptions. This dataset was constructed to produce a digital geologic map as a basis for studying hydrothermal processes in Norris Geyser Basin. The original map does not contain registration tic marks. To create the geodatabase, the original scanned map was georegistered to USGS aerial photographs of the Norris Junction quadrangle collected in 1994. Manmade objects, i.e. roads, parking lots, and the visitor center, along with stream junctions and other hydrographic features, were used for registration.

  10. Global GIS database; digital atlas of Central and South America

    USGS Publications Warehouse

    Hearn,, Paul P.; Hare, T.; Schruben, P.; Sherrill, D.; LaMar, C.; Tsushima, P.

    2000-01-01

    This CD-ROM contains a digital atlas of the countries of Central and South America. This atlas is part of a global database compiled from USGS and other data sources at the nominal scale of 1:1 million and is intended to be used as a regional-scale reference and analytical tool by government officials, researchers, the private sector, and the general public. The atlas includes free GIS software or may also be used with ESRI's ArcView software. Customized ArcView tools, specifically designed to make the atlas easier to use, are also included. The atlas contains the following datasets: country political boundaries, digital shaded relief map, elevation, slope, hydrology, locations of cities and towns, airfields, roads, railroads, utility lines, population density, geology, ecological regions, historical seismicity, volcanoes, ore deposits, oil and gas fields, climate data, landcover, vegetation index, and lights at night.

  11. Biomonitoring of atmospheric pollution by moss bags: Discriminating urban-rural structure in a fragmented landscape.

    PubMed

    Capozzi, F; Giordano, S; Di Palma, A; Spagnuolo, V; De Nicola, F; Adamo, P

    2016-04-01

    In this paper we investigated the possibility to use moss bags to detect pollution inputs - metals, metalloids and polycyclic aromatic hydrocarbons (PAHs) - in sites chosen for their different land use (agricultural, urban/residential scenarios) and proximity to roads (sub-scenarios), in a fragmented conurbation of Campania (southern Italy). We focused on thirty-nine elements including rare earths. For most of them, moss uptake was higher in agricultural than in urban scenarios and in front road sites. Twenty PAHs were analyzed in a subset of agricultural sites; 4- and 5-ringed PAHs were the most abundant, particularly chrysene, fluoranthene and pyrene. Overall results indicated that investigated pollutants have a similar spatial distribution pattern over the entire study area, with road traffic and agricultural practices as the major diffuse pollution sources. Moss bags proved a very sensitive tool, able to discriminate between different land use scenarios and proximity to roads in a mixed rural-urban landscape. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Reproducing ten years of road ageing--accelerated carbonation and leaching of EAF steel slag.

    PubMed

    Suer, Pascal; Lindqvist, Jan-Erik; Arm, Maria; Frogner-Kockum, Paul

    2009-09-01

    Reuse of industrial aggregates is still hindered by concern for their long-term properties. This paper proposes a laboratory method for accelerated ageing of steel slag, to predict environmental and technical properties, starting from fresh slag. Ageing processes in a 10-year old asphalt road with steel slag of electric arc furnace (EAF) type in the subbase were identified by scanning electron microscopy (SEM) and leaching tests. Samples from the road centre and the pavement edge were compared with each other and with samples of fresh slag. It was found that slag from the pavement edge showed traces of carbonation and leaching processes, whereas the road centre material was nearly identical to fresh slag, in spite of an accessible particle structure. Batches of moisturized road centre material exposed to oxygen, nitrogen or carbon dioxide (CO2) were used for accelerated ageing. Time (7-14 days), temperature (20-40 degrees C) and initial slag moisture content (8-20%) were varied to achieve the carbonation (decrease in pH) and leaching that was observed in the pavement edge material. After ageing, water was added to assess leaching of metals and macroelements. 12% moisture, CO2 and seven days at 40 degrees C gave the lowest pH value. This also reproduced the observed ageing effect for Ca, Cu, Ba, Fe, Mn, Pb, Ca (decreased leaching) and for V, Si, and Al (increased leaching). However, ageing effects on SO4, DOC and Cr were not reproduced.

  13. An Energy-Efficient Cluster-Based Vehicle Detection on Road Network Using Intention Numeration Method

    PubMed Central

    Devasenapathy, Deepa; Kannan, Kathiravan

    2015-01-01

    The traffic in the road network is progressively increasing at a greater extent. Good knowledge of network traffic can minimize congestions using information pertaining to road network obtained with the aid of communal callers, pavement detectors, and so on. Using these methods, low featured information is generated with respect to the user in the road network. Although the existing schemes obtain urban traffic information, they fail to calculate the energy drain rate of nodes and to locate equilibrium between the overhead and quality of the routing protocol that renders a great challenge. Thus, an energy-efficient cluster-based vehicle detection in road network using the intention numeration method (CVDRN-IN) is developed. Initially, sensor nodes that detect a vehicle are grouped into separate clusters. Further, we approximate the strength of the node drain rate for a cluster using polynomial regression function. In addition, the total node energy is estimated by taking the integral over the area. Finally, enhanced data aggregation is performed to reduce the amount of data transmission using digital signature tree. The experimental performance is evaluated with Dodgers loop sensor data set from UCI repository and the performance evaluation outperforms existing work on energy consumption, clustering efficiency, and node drain rate. PMID:25793221

  14. An energy-efficient cluster-based vehicle detection on road network using intention numeration method.

    PubMed

    Devasenapathy, Deepa; Kannan, Kathiravan

    2015-01-01

    The traffic in the road network is progressively increasing at a greater extent. Good knowledge of network traffic can minimize congestions using information pertaining to road network obtained with the aid of communal callers, pavement detectors, and so on. Using these methods, low featured information is generated with respect to the user in the road network. Although the existing schemes obtain urban traffic information, they fail to calculate the energy drain rate of nodes and to locate equilibrium between the overhead and quality of the routing protocol that renders a great challenge. Thus, an energy-efficient cluster-based vehicle detection in road network using the intention numeration method (CVDRN-IN) is developed. Initially, sensor nodes that detect a vehicle are grouped into separate clusters. Further, we approximate the strength of the node drain rate for a cluster using polynomial regression function. In addition, the total node energy is estimated by taking the integral over the area. Finally, enhanced data aggregation is performed to reduce the amount of data transmission using digital signature tree. The experimental performance is evaluated with Dodgers loop sensor data set from UCI repository and the performance evaluation outperforms existing work on energy consumption, clustering efficiency, and node drain rate.

  15. 'Surfing the Silk Road': a study of users' experiences.

    PubMed

    Van Hout, Marie Claire; Bingham, Tim

    2013-11-01

    The online drug marketplace called 'Silk Road' has operated anonymously on the 'Deep Web' since 2011. It is accessible through computer encrypting software (Tor) and is supported by online transactions using peer to peer anonymous and untraceable crypto-currency (Bit Coins). The study aimed to describe user motives and realities of accessing, navigating and purchasing on the 'Silk Road' marketplace. Systematic online observations, monitoring of discussion threads on the site during four months of fieldwork and analysis of anonymous online interviews (n=20) with a convenience sample of adult 'Silk Road' users was conducted. The majority of participants were male, in professional employment or in tertiary education. Drug trajectories ranged from 18 months to 25 years, with favourite drugs including MDMA, 2C-B, mephedrone, nitrous oxide, ketamine, cannabis and cocaine. Few reported prior experience of online drug sourcing. Reasons for utilizing 'Silk Road' included curiosity, concerns for street drug quality and personal safety, variety of products, anonymous transactioning, and ease of product delivery. Vendor selection appeared to be based on trust, speed of transaction, stealth modes and quality of product. Forums on the site provided user advice, trip reports, product and transaction reviews. Some users reported solitary drug use for psychonautic and introspective purposes. A minority reported customs seizures, and in general a displacement away from traditional drug sourcing (street and closed markets) was described. Several reported intentions to commence vending on the site. The study provides an insight into 'Silk Road' purchasing motives and processes, the interplay between traditional and 'Silk Road' drug markets, the 'Silk Road' online community and its communication networks. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Traffic condition with road upgrading during construction and operation stages based on level-of-service (LOS)

    NASA Astrophysics Data System (ADS)

    Tay, A. C.; Lee, H. H.

    2018-04-01

    In this study, traffic survey was done at signalized intersection of both ends of an upgrading road during morning and afternoon peak hours throughout construction period. The intersections of Tudan Road located at Miri City in Sarawak State, Malaysia were chosen as study sites. The aim of this research was to investigate the traffic condition for the signalized intersections of a R3 secondary road that being upgrading to standard U5 dual carriageway during peak hours for construction and operation stages. Data collected from these sites were analyzed according to Highway Capacity Manual (HCM) 2010. From the results, the level-of-services (LOS) of Kuala Baram By Pass Road intersection improved from Level F to Level E at operation stage for weekday during peak hours in the morning. LOS of Lutong-Kuala Baram Road intersection at construction stage were Level C during peak hours in the morning and Level D during peak hours in the afternoon for weekends. However, the LOS during both peak hours for weekends were projected to improve to Level B at the operation stage. It proved that the road construction has affected LOS, and this temporary issue can be solved after the upgraded road is in operation.

  17. Thermodynamics-hydration relationships within loops that affect G-quadruplexes under molecular crowding conditions.

    PubMed

    Fujimoto, Takeshi; Nakano, Shu-ichi; Sugimoto, Naoki; Miyoshi, Daisuke

    2013-01-31

    We systematically investigated the effects of loop length on the conformation, thermodynamic stability, and hydration of DNA G-quadruplexes under dilute and molecular crowding conditions in the presence of Na(+). Structural analysis showed that molecular crowding induced conformational switches of oligonucleotides with the longer guanine stretch and the shorter thymine loop. Thermodynamic parameters further demonstrated that the thermodynamic stability of G-quadruplexes increased by increasing the loop length from two to four, whereas it decreased by increasing the loop length from four to six. Interestingly, we found by osmotic pressure analysis that the number of water molecules released from the G-quadruplex decreased with increasing thermodynamic stability. We assumed that base-stacking interactions within the loops not only stabilized the whole G-quadruplex structure but also created hydration sites by accumulating nucleotide functional groups. The molecular crowding effects on the stability of G-quadruplexes composed of abasic sites, which reduce the stacking interactions at the loops, further demonstrated that G-quadruplexes with fewer stacking interactions within the loops released a larger number of water molecules upon folding. These results showed that the stacking interactions within the loops determined the thermodynamic stability and hydration of the whole G-quadruplex.

  18. Delivery quality assurance with ArcCHECK

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neilson, Christopher; Klein, Michael; Barnett, Rob

    2013-04-01

    Radiation therapy requires delivery quality assurance (DQA) to ensure that treatment is accurate and closely follows the plan. We report our experience with the ArcCHECK phantom and investigate its potential optimization for the DQA process. One-hundred seventy DQA plans from 84 patients were studied. Plans were classified into 2 groups: those with the target situated on the diodes of the ArcCHECK (D plans) and those with the target situated at the center (C plans). Gamma pass rates for 8 target sites were examined. The parameters used to analyze the data included 3%/3 mm with the Van Dyk percent difference criteriamore » (VD) on, 3%/3 mm with the VD off, 2%/2 mm with the VD on, and x/3 mm with the VD on and the percentage dosimetric agreement “x” for diode plans adjusted. D plans typically displayed maximum planned dose (MPD) on the cylindrical surface containing ArcCHECK diodes than center plans, resulting in inflated gamma pass rates. When this was taken into account by adjusting the percentage dosimetric agreement, C plans outperformed D plans by an average of 3.5%. ArcCHECK can streamline the DQA process, consuming less time and resources than radiographic films. It is unnecessary to generate 2 DQA plans for each patient; a single center plan will suffice. Six of 8 target sites consistently displayed pass rates well within our acceptance criteria; the lesser performance of head and neck and spinal sites can be attributed to marginally lower doses and increased high gradient of plans.« less

  19. Assessing impacts of roads: application of a standard assessment protocol

    USGS Publications Warehouse

    Duniway, Michael C.; Herrick, Jeffrey E.

    2013-01-01

    Adaptive management of road networks depends on timely data that accurately reflect the impacts those systems are having on ecosystem processes and associated services. In the absence of reliable data, land managers are left with little more than observations and perceptions to support management decisions of road-associated disturbances. Roads can negatively impact the soil, hydrologic, plant, and animal processes on which virtually all ecosystem services depend. The Interpreting Indicators of Rangeland Health (IIRH) protocol is a qualitative method that has been demonstrated to be effective in characterizing impacts of roads. The goal of this study were to develop, describe, and test an approach for using IIRH to systematically evaluate road impacts across large, diverse arid and semiarid landscapes. We developed a stratified random sampling approach to plot selection based on ecological potential, road inventory data, and image interpretation of road impacts. The test application on a semiarid landscape in southern New Mexico, United States, demonstrates that the approach developed is sensitive to road impacts across a broad range of ecological sites but that not all the types of stratification were useful. Ecological site and road inventory strata accounted for significant variability in the functioning of ecological processes but stratification based on apparent impact did not. Analysis of the repeatability of IIRH applied to road plots indicates that the method is repeatable but consensus evaluations based on multiple observers should be used to minimize risk of bias. Landscape-scale analysis of impacts by roads of contrasting designs (maintained dirt or gravel roads vs. non- or infrequently maintained roads) suggests that future travel management plans for the study area should consider concentrating traffic on fewer roads that are well designed and maintained. Application of the approach by land managers will likely provide important insights into minimizing impacts of road networks on key ecosystem services.

  20. An experimental investigation into the effects of traffic noise on distributions of birds: avoiding the phantom road

    PubMed Central

    McClure, Christopher J. W.; Ware, Heidi E.; Carlisle, Jay; Kaltenecker, Gregory; Barber, Jesse R.

    2013-01-01

    Many authors have suggested that the negative effects of roads on animals are largely owing to traffic noise. Although suggestive, most past studies of the effects of road noise on wildlife were conducted in the presence of the other confounding effects of roads, such as visual disturbance, collisions and chemical pollution among others. We present, to our knowledge, the first study to experimentally apply traffic noise to a roadless area at a landscape scale—thus avoiding the other confounding aspects of roads present in past studies. We replicated the sound of a roadway at intervals—alternating 4 days of noise on with 4 days off—during the autumn migratory period using a 0.5 km array of speakers within an established stopover site in southern Idaho. We conducted daily bird surveys along our ‘Phantom Road’ and in a nearby control site. We document over a one-quarter decline in bird abundance and almost complete avoidance by some species between noise-on and noise-off periods along the phantom road and no such effects at control sites—suggesting that traffic noise is a major driver of effects of roads on populations of animals. PMID:24197411

  1. Behavioral responses of wolves to roads: scale-dependent ambivalence

    PubMed Central

    Nelson, Lindsey; Wabakken, Petter; Sand, Håkan; Liberg, Olof

    2014-01-01

    Throughout their recent recovery in several industrialized countries, large carnivores have had to cope with a changed landscape dominated by human infrastructure. Population growth depends on the ability of individuals to adapt to these changes by making use of new habitat features and at the same time to avoid increased risks of mortality associated with human infrastructure. We analyzed the summer movements of 19 GPS-collared resident wolves (Canis lupus L.) from 14 territories in Scandinavia in relation to roads. We used resource and step selection functions, including >12000 field-checked GPS-positions and 315 kill sites. Wolves displayed ambivalent responses to roads depending on the spatial scale, road type, time of day, behavioral state, and reproductive status. At the site scale (approximately 0.1 km2), they selected for roads when traveling, nearly doubling their travel speed. Breeding wolves moved the fastest. At the patch scale (10 km2), house density rather than road density was a significant negative predictor of wolf patch selection. At the home range scale (approximately 1000 km2), breeding wolves increased gravel road use with increasing road availability, although at a lower rate than expected. Wolves have adapted to use roads for ease of travel, but at the same time developed a cryptic behavior to avoid human encounters. This behavioral plasticity may have been important in allowing the successful recovery of wolf populations in industrialized countries. However, we emphasize the role of roads as a potential cause of increased human-caused mortality. PMID:25419085

  2. Behavioral responses of wolves to roads: scale-dependent ambivalence.

    PubMed

    Zimmermann, Barbara; Nelson, Lindsey; Wabakken, Petter; Sand, Håkan; Liberg, Olof

    2014-11-01

    Throughout their recent recovery in several industrialized countries, large carnivores have had to cope with a changed landscape dominated by human infrastructure. Population growth depends on the ability of individuals to adapt to these changes by making use of new habitat features and at the same time to avoid increased risks of mortality associated with human infrastructure. We analyzed the summer movements of 19 GPS-collared resident wolves ( Canis lupus L.) from 14 territories in Scandinavia in relation to roads. We used resource and step selection functions, including >12000 field-checked GPS-positions and 315 kill sites. Wolves displayed ambivalent responses to roads depending on the spatial scale, road type, time of day, behavioral state, and reproductive status. At the site scale (approximately 0.1 km 2 ), they selected for roads when traveling, nearly doubling their travel speed. Breeding wolves moved the fastest. At the patch scale (10 km 2 ), house density rather than road density was a significant negative predictor of wolf patch selection. At the home range scale (approximately 1000 km 2 ), breeding wolves increased gravel road use with increasing road availability, although at a lower rate than expected. Wolves have adapted to use roads for ease of travel, but at the same time developed a cryptic behavior to avoid human encounters. This behavioral plasticity may have been important in allowing the successful recovery of wolf populations in industrialized countries. However, we emphasize the role of roads as a potential cause of increased human-caused mortality.

  3. Linear matrix inequality-based nonlinear adaptive robust control with application to unmanned aircraft systems

    NASA Astrophysics Data System (ADS)

    Kun, David William

    Unmanned aircraft systems (UASs) are gaining popularity in civil and commercial applications as their lightweight on-board computers become more powerful and affordable, their power storage devices improve, and the Federal Aviation Administration addresses the legal and safety concerns of integrating UASs in the national airspace. Consequently, many researchers are pursuing novel methods to control UASs in order to improve their capabilities, dependability, and safety assurance. The nonlinear control approach is a common choice as it offers several benefits for these highly nonlinear aerospace systems (e.g., the quadrotor). First, the controller design is physically intuitive and is derived from well known dynamic equations. Second, the final control law is valid in a larger region of operation, including far from the equilibrium states. And third, the procedure is largely methodical, requiring less expertise with gain tuning, which can be arduous for a novice engineer. Considering these facts, this thesis proposes a nonlinear controller design method that combines the advantages of adaptive robust control (ARC) with the powerful design tools of linear matrix inequalities (LMI). The ARC-LMI controller is designed with a discontinuous projection-based adaptation law, and guarantees a prescribed transient and steady state tracking performance for uncertain systems in the presence of matched disturbances. The norm of the tracking error is bounded by a known function that depends on the controller design parameters in a known form. Furthermore, the LMI-based part of the controller ensures the stability of the system while overcoming polytopic uncertainties, and minimizes the control effort. This can reduce the number of parameters that require adaptation, and helps to avoid control input saturation. These desirable characteristics make the ARC-LMI control algorithm well suited for the quadrotor UAS, which may have unknown parameters and may encounter external disturbances such as wind gusts and turbulence. This thesis develops the ARC-LMI attitude and position controllers for an X-configuration quadrotor helicopter. The inner-loop of the autopilot controls the attitude and altitude of the quadrotor, and the outer-loop controls its position in the earth-fixed coordinate frame. Furthermore, by intelligently generating a smooth trajectory from the given reference coordinates (waypoints), the transient performance is improved. The simulation results indicate that the ARC-LMI controller design is useful for a variety of quadrotor applications, including precise trajectory tracking, autonomous waypoint navigation in the presence of disturbances, and package delivery without loss of performance.

  4. Cultural Resource Predictive Model Literature and Records Search for Conesus Lake N.Y.

    DTIC Science & Technology

    1980-02-01

    The Cameron site is a 13 historic burial site at Lima , 9.6 km northeast of Conesus Lake (Wray 1966). The southerrmost, and the earliest, of the his...toric Seneca sites (Adams and Tram) are located on a long hillbetween the towns of Lima and Livonia. The latter town is1,600 i northeast of Conesus...Project in Livingston County. One section of this survey extends northwest of the Conesus Lake project area along the Lima Road and Pole Bridge Road

  5. Nonlinear identification of the total baroreflex arc: chronic hypertension model.

    PubMed

    Moslehpour, Mohsen; Kawada, Toru; Sunagawa, Kenji; Sugimachi, Masaru; Mukkamala, Ramakrishna

    2016-05-01

    The total baroreflex arc is the open-loop system relating carotid sinus pressure (CSP) to arterial pressure (AP). Its linear dynamic functioning has been shown to be preserved in spontaneously hypertensive rats (SHR). However, the system is known to exhibit nonlinear dynamic behaviors. The aim of this study was to establish nonlinear dynamic models of the total arc (and its subsystems) in hypertensive rats and to compare these models with previously published models for normotensive rats. Hypertensive rats were studied under anesthesia. The vagal and aortic depressor nerves were sectioned. The carotid sinus regions were isolated and attached to a servo-controlled piston pump. AP and sympathetic nerve activity were measured while CSP was controlled via the pump using Gaussian white noise stimulation. Second-order, nonlinear dynamics models were developed by application of nonparametric system identification to a portion of the measurements. The models of the total arc predicted AP 21-43% better (P < 0.005) than conventional linear dynamic models in response to a new portion of the CSP measurement. The linear and nonlinear terms of these validated models were compared with the corresponding terms of an analogous model for normotensive rats. The nonlinear gains for the hypertensive rats were significantly larger than those for the normotensive rats [-0.38 ± 0.04 (unitless) vs. -0.22 ± 0.03, P < 0.01], whereas the linear gains were similar. Hence, nonlinear dynamic functioning of the sympathetically mediated total arc may enhance baroreflex buffering of AP increases more in SHR than normotensive rats. Copyright © 2016 the American Physiological Society.

  6. 33 CFR 211.78 - Maintenance and conveyance of access roads.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Site Development and Use § 211.78 Maintenance and conveyance of access roads. The Government will not... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Maintenance and conveyance of access roads. 211.78 Section 211.78 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE...

  7. A method for measuring sediment production from forest roads.

    Treesearch

    Keith Kahklen

    2001-01-01

    Predicting sediment production from forest roads is necessary to determine their impact on watersheds and associated terrestrial and stream biota. A method is presented for measuring sediment originating from a road segment for individual storm events and quantifying the delivery to streams. Site selection criteria are listed to describe the characteristics for...

  8. Structural Basis for Inactivation of the Human Pyruvate Dehydrogenase Complex by Phosphorylation: Role of Disordered Phosphorylation Loops

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kato, Masato; Wynn, R. Max; Chuang, Jacinta L.

    2009-09-11

    We report the crystal structures of the phosporylated pyruvate dehydrogenase (E1p) component of the human pyruvate dehydrogenase complex (PDC). The complete phosphorylation at Ser264-{alpha} (site 1) of a variant E1p protein was achieved using robust pyruvate dehydrogenase kinase 4 free of the PDC core. We show that unlike its unmodified counterpart, the presence of a phosphoryl group at Ser264-{alpha} prevents the cofactor thiamine diphosphate-induced ordering of the two loops carrying the three phosphorylation sites. The disordering of these phosphorylation loops is caused by a previously unrecognized steric clash between the phosphoryl group at site 1 and a nearby Ser266-{alpha}, whichmore » nullifies a hydrogen-bonding network essential for maintaining the loop conformations. The disordered phosphorylation loops impede the binding of lipoyl domains of the PDC core to E1p, negating the reductive acetylation step. This results in the disruption of the substrate channeling in the PDC, leading to the inactivation of this catalytic machine.« less

  9. Clinical utility of RapidArc™ radiotherapy technology

    PubMed Central

    Infusino, Erminia

    2015-01-01

    RapidArc™ is a radiation technique that delivers highly conformal dose distributions through the complete rotation (360°) and speed variation of the linear accelerator gantry. This technique, called volumetric modulated arc therapy (VMAT), compared with conventional radiotherapy techniques, can achieve high-target volume coverage and sparing damage to normal tissues. RapidArc delivers precise dose distribution and conformity similar to or greater than intensity-modulated radiation therapy in a short time, generally a few minutes, to which image-guided radiation therapy is added. RapidArc has become a currently used technology in many centers, which use RapidArc technology to treat a large number of patients. Large and small hospitals use it to treat the most challenging cases, but more and more frequently for the most common cancers. The clinical use of RapidArc and VMAT technology is constantly growing. At present, a limited number of clinical data are published, mostly concerning planning and feasibility studies. Clinical outcome data are increasing for a few tumor sites, even if only a little. The purpose of this work is to discuss the current status of VMAT techniques in clinical use through a review of the published data of planning systems and clinical outcomes in several tumor sites. The study consisted of a systematic review based on analysis of manuscripts retrieved from the PubMed, BioMed Central, and Scopus databases by searching for the keywords “RapidArc”, “Volumetric modulated arc radiotherapy”, and “Intensity-modulated radiotherapy”. PMID:26648755

  10. Brownfields Road Map

    EPA Pesticide Factsheets

    The Brownfields Road Map publication and companion website provide a general outline of how to assess and clean up a brownfields site and introduce stakeholders to a range of technology options and available resources.

  11. 1. Northeast face of missile site control building, commonly known ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Northeast face of missile site control building, commonly known as the missile site radar building, showing open blast door #BD2. This emergency escape, at stair no. 12, is NEMP/RFI-shielded and 16" thick. The large circle in the center is the radar face, also known as the antennae array aperture. The small circle to the right of the radar face is the "Q" channel. The antennae atop the turret provided lightning protection for the building - Stanley R. Mickelsen Safeguard Complex, Missile Site Control Building, Northeast of Tactical Road; southeast of Tactical Road South, Nekoma, Cavalier County, ND

  12. Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites

    PubMed Central

    Moise, Gwendolyn; Gallup, Nathan M.; Alexandrova, Anastassia N.; Hengge, Alvan C.; Johnson, Sean J.

    2016-01-01

    Catalysis in protein tyrosine phosphatases (PTPs) involves movement of a protein loop called the WPD loop that brings a conserved aspartic acid into the active site to function as a general acid. Mutation of the tryptophan in the WPD loop of the PTP YopH to any other residue with a planar, aromatic side chain (phenylalanine, tyrosine, or histidine) disables general acid catalysis. Crystal structures reveal these conservative mutations leave this critical loop in a catalytically unproductive, quasi-open position. Although the loop positions in crystal structures are similar for all three conservative mutants, the reasons inhibiting normal loop closure differ for each mutant. In the W354F and W354Y mutants, steric clashes result from six-membered rings occupying the position of the five-membered ring of the native indole side chain. The histidine mutant dysfunction results from new hydrogen bonds stabilizing the unproductive position. The results demonstrate how even modest modifications can disrupt catalytically important protein dynamics. Crystallization of all the catalytically compromised mutants in the presence of vanadate gave rise to vanadate dimers at the active site. In W354Y and W354H, a divanadate ester with glycerol is observed. Such species have precedence in solution and are known from the small molecule crystal database. Such species have not been observed in the active site of a phosphatase, as a functional phosphatase would rapidly catalyze their decomposition. The compromised functionality of the mutants allows the trapping of species that undoubtedly form in solution and are capable of binding at the active sites of PTPs, and, presumably, other phosphatases. In addition to monomeric vanadate, such higher-order vanadium-based molecules are likely involved in the interaction of vanadate with PTPs in solution. PMID:26445170

  13. Temperature Contours around Milford FORGE site

    DOE Data Explorer

    Joe Moore

    2016-03-09

    This submission contains several ArcGIS shapefiles, each with Temperature contour lines at different depths. Subsurface temperature were important for characterizing the geothermal system beneath the FORGE site in Milford, Utah.

  14. Applications of Mobile GIS in Forestry South Australia

    NASA Astrophysics Data System (ADS)

    Battad, D. T.; Mackenzie, P.

    2012-07-01

    South Australian Forestry Corporation (ForestrySA) had been actively investigating the applications of mobile GIS in forestry for the past few years. The main objective is to develop an integrated mobile GIS capability that allows staff to collect new spatial information, verify existing data, and remotely access and post data from the field. Two (2) prototype mobile GIS applications have been developed already using the Environmental Systems Research Institute (ESRI) ARCGISR technology as the main spatial component. These prototype systems are the Forest Health Surveillance System and the Mobile GIS for Wetlands System. The Forest Health Surveillance System prototype is used primarily for aerial forest health surveillance. It was developed using a tablet PC with ArcMapR GIS. A customised toolbar was developed using ArcObjectsR in the Visual Basic 6 Integrated Development Environment (IDE). The resulting dynamic linked library provides a suite of custom tools which enables the following: - quickly create spatial features and attribute the data - full utilisation of global positioning system (GPS) technology - excellent screen display navigation tools, i.e. pan, rotate map, capture of flight path - seamless integration of data into GIS as geodatabase (GDB) feature classes - screen entry of text and conversion to annotation feature classes The Mobile GIS for Wetlands System prototype was developed for verifying existing wetland areas within ForestrySA's plantation estate, collect new wetland data, and record wetland conditions. Mapping of actual wetlands within ForestrySA's plantation estate is very critical because of the need to establish protection buffers around these features during the implementation of plantation operations. System development has been focussed on a mobile phone platform (HTC HD2R ) with WindowsR Mobile 6, ESRI's ArcGISR Mobile software development kit (SDK) employing ArcObjectsR written on C#.NET IDE, and ArcGIS ServerR technology. The system is also implemented in the VILIVR X70. The system has undergone testing by ForestrySA staff and the refinements had been incorporated in the latest version of the system. The system has the following functionalities: - display and query strategic data layers - collect and edit spatial and attribute data - full utilisation of global positioning GPS technology - distance and area measurements - display of high resolution imagery - seamless integration of data into GIS as feature classes - screen display and navigation tools, i.e. pan, zoom in/out, rotate map - capture of flight path The next stages in the development of mobile GIS technologies at ForestrySA are to enhance the systems' capabilities as one of the organization main data capture systems. These include incorporating other applications, e.g. roads/tracks mapping, mapping of significant sites, etc., and migration of the system to Windows Phone7.

  15. The Lumenal Loop Met672–Pro707 of Copper-transporting ATPase ATP7A Binds Metals and Facilitates Copper Release from the Intramembrane Sites*

    PubMed Central

    Barry, Amanda N.; Otoikhian, Adenike; Bhatt, Sujata; Shinde, Ujwal; Tsivkovskii, Ruslan; Blackburn, Ninian J.; Lutsenko, Svetlana

    2011-01-01

    The copper-transporting ATPase ATP7A has an essential role in human physiology. ATP7A transfers the copper cofactor to metalloenzymes within the secretory pathway; inactivation of ATP7A results in an untreatable neurodegenerative disorder, Menkes disease. Presently, the mechanism of ATP7A-mediated copper release into the secretory pathway is not understood. We demonstrate that the characteristic His/Met-rich segment Met672–Pro707 (HM-loop) that connects the first two transmembrane segments of ATP7A is important for copper release. Mutations within this loop do not prevent the ability of ATP7A to form a phosphorylated intermediate during ATP hydrolysis but inhibit subsequent dephosphorylation, a step associated with copper release. The HM-loop inserted into a scaffold protein forms two structurally distinct binding sites and coordinates copper in a mixed His-Met environment with an ∼2:1 stoichiometry. Binding of either copper or silver, a Cu(I) analog, induces structural changes in the loop. Mutations of 4 Met residues to Ile or two His-His pairs to Ala-Gly decrease affinity for copper. Altogether, the data suggest a two-step process, where copper released from the transport sites binds to the first His(Met)2 site, triggering a structural change and binding to a second 2-coordinate His-His or His-Met site. We also show that copper binding within the HM-loop stabilizes Cu(I) and protects it from oxidation, which may further aid the transfer of copper from ATP7A to acceptor proteins. The mechanism of copper entry into the secretory pathway is discussed. PMID:21646353

  16. Effectiveness of highway-drainage systems in preventing contamination of ground water by road salt, Route 25, southeastern Massachusetts; description of study area, data collection programs, and methodology

    USGS Publications Warehouse

    Church, P.E.; Armstrong, D.S.; Granato, G.E.; Stone, V.J.; Smith, K.P.; Provencher, P.L.

    1996-01-01

    Four test sites along a 7-mile section of Route 25 in southeastern Massachusetts, each representing a specific highway-drainage system, were instrumented to determine the effectiveness of the drainage systems in preventing contamination of ground water by road salt. One of the systems discharges highway runoff onsite through local drainpipes. The other systems use trunkline drainpipes through which runoff from highway surfaces, shoulders, and median strips is diverted and discharged into either a local stream or a coastal waterway. Route 25 was completed and opened to traffic in the summer of 1987. Road salt was first applied to the highway in the winter of 1987-88. The study area is on a thick outwash plain composed primarily of sand and gravel. Water-table depths range from 15 to 60 feet below land surface at the four test sites. Ground-water flow is in a general southerly direction, approximately perpendicular to the highway. Streamflow in the study area is controlled primarily by ground-water discharge. Background concentrations of dissolved chloride, sodium, and calcium-the primary constituents of road salt-are similar in ground water and surface water and range from 5 to 20, 5 to 10, and 1 to 5 milligrams per liter, respectively. Data-collection programs were developed for monitoring the application of road salt to the highway, the quantity of road-salt water entering the ground water, diverted through the highway-drainage systems, and entering a local stream. The Massachusetts Highway Department monitored road salt applied to the highway and reported these data to the U.S. Geological Survey. The U.S. Geological Survey designed and operated the ground-water, highway- drainage, and surface-water data-collection programs. A road-salt budget will be calculated for each test site so that the effectiveness of the different highway-drainage systems in preventing contamination of ground water by road salt can be determined.

  17. Large microplastic particles in sediments of tributaries of the River Thames, UK - Abundance, sources and methods for effective quantification.

    PubMed

    Horton, Alice A; Svendsen, Claus; Williams, Richard J; Spurgeon, David J; Lahive, Elma

    2017-01-15

    Sewage effluent input and population were chosen as predictors of microplastic presence in sediments at four sites in the River Thames basin (UK). Large microplastic particles (1mm-4mm) were extracted using a stepwise approach to include visual extraction, flotation and identification using Raman spectroscopy. Microplastics were found at all four sites. One site had significantly higher numbers of microplastics than other sites, average 66 particles 100g -1 , 91% of which were fragments. This site was downstream of a storm drain outfall receiving urban runoff; many of the fragments at this site were determined to be derived of thermoplastic road-surface marking paints. At the remaining three sites, fibres were the dominant particle type. The most common polymers identified included polypropylene, polyester and polyarylsulphone. This study describes two major new findings: presence of microplastic particles in a UK freshwater system and identification of road marking paints as a source of microplastics. This study is the first to quantify microplastics of any size in river sediments in the UK and links their presence to terrestrial sources including sewage and road marking paints. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

  18. Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity.

    PubMed

    Nancolas, Bethany; Sessions, Richard B; Halestrap, Andrew P

    2015-02-15

    The proton-linked monocarboxylate transporters (MCTs) are required for lactic acid transport into and out of all mammalian cells. Thus, they play an essential role in tumour cells that are usually highly glycolytic and are promising targets for anti-cancer drugs. AR-C155858 is a potent MCT1 inhibitor (Ki ~2 nM) that also inhibits MCT2 when associated with basigin but not MCT4. Previous work [Ovens, M.J. et al. (2010) Biochem. J. 425, 523-530] revealed that AR-C155858 binding to MCT1 occurs from the intracellular side and involves transmembrane helices (TMs) 7-10. In the present paper, we generate a molecular model of MCT4 based on our previous models of MCT1 and identify residues in the intracellular substrate-binding cavity that differ significantly between MCT4 and MCT1/MCT2 and so might account for differences in inhibitor binding. We tested their involvement using site-directed mutagenesis (SDM) of MCT1 to change residues individually or in combination with their MCT4 equivalent and determined inhibitor sensitivity following expression in Xenopus oocytes. Phe360 and Ser364 were identified as important for AR-C155858 binding with the F360Y/S364G mutant exhibiting >100-fold reduction in inhibitor sensitivity. To refine the binding site further, we used molecular dynamics (MD) simulations and additional SDM. This approach implicated six more residues whose involvement was confirmed by both transport studies and [3H]-AR-C155858 binding to oocyte membranes. Taken together, our data imply that Asn147, Arg306 and Ser364 are important for directing AR-C155858 to its final binding site which involves interaction of the inhibitor with Lys38, Asp302 and Phe360 (residues that also play key roles in the translocation cycle) and also Leu274 and Ser278.

  19. Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity

    PubMed Central

    Nancolas, Bethany; Sessions, Richard B.; Halestrap, Andrew P.

    2014-01-01

    The proton-linked monocarboxylate transporters (MCTs) are required for lactic acid transport into and out of all mammalian cells. Thus, they play an essential role in tumour cells that are usually highly glycolytic and are promising targets for anti-cancer drugs. AR-C155858 is a potent MCT1 inhibitor (Ki ~2 nM) that also inhibits MCT2 when associated with basigin but not MCT4. Previous work [Ovens, M.J. et al. (2010) Biochem. J. 425, 523–530] revealed that AR-C155858 binding to MCT1 occurs from the intracellular side and involves transmembrane helices (TMs) 7–10. In the present paper, we generate a molecular model of MCT4 based on our previous models of MCT1 and identify residues in the intracellular substrate-binding cavity that differ significantly between MCT4 and MCT1/MCT2 and so might account for differences in inhibitor binding. We tested their involvement using site-directed mutagenesis (SDM) of MCT1 to change residues individually or in combination with their MCT4 equivalent and determined inhibitor sensitivity following expression in Xenopus oocytes. Phe360 and Ser364 were identified as important for AR-C155858 binding with the F360Y/S364G mutant exhibiting >100-fold reduction in inhibitor sensitivity. To refine the binding site further, we used molecular dynamics (MD) simulations and additional SDM. This approach implicated six more residues whose involvement was confirmed by both transport studies and [3H]-AR-C155858 binding to oocyte membranes. Taken together, our data imply that Asn147, Arg306 and Ser364 are important for directing AR-C155858 to its final binding site which involves interaction of the inhibitor with Lys38, Asp302 and Phe360 (residues that also play key roles in the translocation cycle) and also Leu274 and Ser278. PMID:25437897

  20. Single nucleotide polymorphisms in the mitochondrial displacement loop and outcome of esophageal squamous cell carcinoma.

    PubMed

    Zhang, Ruixing; Wang, Rui; Zhang, Fengbin; Wu, Chensi; Fan, Haiyan; Li, Yan; Wang, Cuiju; Guo, Zhanjun

    2010-11-26

    Accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) has been described for different types of cancers and might be associated with cancer risk and disease outcome. We used a population-based series of esophageal squamous cell carcinoma (ESCC) patients for investigating the prediction power of SNPs in mitochondrial D-loop. The D-loop region of mtDNA was sequenced for 60 ESCC patients recorded in the Fourth Hospital of Hebei Medical University between 2003 and 2004. The 5 year survival curve were calculated with the Kaplan-Meier method and compared by the log-rank test at each SNP site, a multivariate survival analysis was also performed with the Cox proportional hazards method. The SNP sites of nucleotides 16274G/A, 16278C/T and 16399A/G were identified for prediction of post-operational survival by the log-rank test. In an overall multivariate analysis, the 16278 and 16399 alleles were identified as independent predictors of ESCC outcome. The length of survival of patients with the minor allele 16278T genotype was significantly shorter than that of patients with 16278C at the 16278 site (relative risk, 3.001; 95% CI, 1.029 - 8.756; p = 0.044). The length of survival of patients with the minor allele 16399G genotype was significantly shorter than that of patients with the more frequent allele 16399A at the 16399 site in ESCC patients (relative risk, 3.483; 95% CI, 1.068 - 11.359; p = 0.039). Genetic polymorphisms in the D-loop are independent prognostic markers for patients with ESCC. Accordingly, the analysis of genetic polymorphisms in the mitochondrial D-loop can help identify patient subgroups at high risk of a poor disease outcome.

  1. 78 FR 25465 - Notice of Proposed Withdrawal and Opportunity for Public Meeting; AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... protection of the Glacier Loop Administrative Site in Alaska. The withdrawal created by PLO No. 7177 will... . Persons who use a Telecommunications Device for the Deaf (TDD) may call the Federal Information Relay... the protection of the Glacier Loop Administrative Site. PLO No. 7177 is incorporated herein by...

  2. A method for assessing the physical recovery of Antarctic desert pavements following human-induced disturbances: a case study in the Ross Sea region of Antarctica.

    PubMed

    O'Neill, Tanya A; Balks, Megan R; López-Martínez, Jerónimo; McWhirter, Judi L

    2012-12-15

    With increasing visitor numbers an understanding of the impacts of human activities in Antarctic terrestrial environments has become important. The objective of this study was to develop a means for assessing recovery of the ground surface desert pavement following physical disturbance. A set of 11 criteria were identified to assess desert pavement recovery. Assessed criteria were: embeddedness of surface clasts; impressions of removed clasts; degree of clast surface weathering; % overturned clasts; salt on underside of clasts; development of salt coatings; armouring per m(2); colour contrast; evidence of subsidence/melt out; accumulation of salt on cut surfaces; and evidence of patterned ground development. Recovery criteria were assigned a severity/extent rating on a scale from zero to four, zero being highly disturbed, and four being undisturbed. A relative % recovery for each criteria was calculated for each site by comparison with a nearby undisturbed control area, and an overall Mean Recovery Index (MRI) was assigned to each pavement surface. To test the method, 54 sites in the Ross Sea region of Antarctica were investigated including areas disturbed by: bulldozer scraping for road-fill, contouring for infrastructure, geotechnical investigations, and experimental treading trial sites. Disturbances had occurred at timescales ranging from one week to 50 years prior to assessment. The extent of desert pavement recovery at the sites investigated in this study was higher than anticipated. Fifty of the 54 sites investigated were in an intermediate, or higher, stage of desert pavement recovery, 30 sites were in an advanced stage of recovery, and four sites were indistinguishable from adjacent control sites (MRI = 100%). It was found that active surfaces, such as the gravel beach deposits at the Greenpeace World Park Base site at Cape Evans, the aeolian sand deposits at Bull Pass, and the alluvial fan deposits of the Loop Moraine field campsite, recovered relatively quickly, whereas less active sites, such as the bulldozed tracks at Marble Point, and Williams Field to McMurdo Station pipeline site on Ross Island, showed only intermediate recovery 20-30 years after disturbance. The slabby grano-diorite surface material at the former Vanda Station site, meant that the impacts that had occurred were hard to detect following decommissioning of the station and site remediation. Desert pavements disturbed by randomly dispersed footprints, temporary field campsites at the Loop Moraine and VXE6 Pond in the Wright Valley, recovered to be undetectable (MRI = 100%) within five years, whereas track formation from repeated trampling, particularly the concentration of larger clasts along the margin of a confined track, persisted for over 15 years (MRI = 82%). The recovery assessment method developed in this study has environmental management applications and potential to advance our ability to predict the recovery of desert pavement following human impacts from activities in Antarctica. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Trajectory generation for an on-road autonomous vehicle

    NASA Astrophysics Data System (ADS)

    Horst, John; Barbera, Anthony

    2006-05-01

    We describe an algorithm that generates a smooth trajectory (position, velocity, and acceleration at uniformly sampled instants of time) for a car-like vehicle autonomously navigating within the constraints of lanes in a road. The technique models both vehicle paths and lane segments as straight line segments and circular arcs for mathematical simplicity and elegance, which we contrast with cubic spline approaches. We develop the path in an idealized space, warp the path into real space and compute path length, generate a one-dimensional trajectory along the path length that achieves target speeds and positions, and finally, warp, translate, and rotate the one-dimensional trajectory points onto the path in real space. The algorithm moves a vehicle in lane safely and efficiently within speed and acceleration maximums. The algorithm functions in the context of other autonomous driving functions within a carefully designed vehicle control hierarchy.

  4. Complexity in built environment, health, and destination walking: a neighborhood-scale analysis.

    PubMed

    Carlson, Cynthia; Aytur, Semra; Gardner, Kevin; Rogers, Shannon

    2012-04-01

    This study investigates the relationships between the built environment, the physical attributes of the neighborhood, and the residents' perceptions of those attributes. It focuses on destination walking and self-reported health, and does so at the neighborhood scale. The built environment, in particular sidewalks, road connectivity, and proximity of local destinations, correlates with destination walking, and similarly destination walking correlates with physical health. It was found, however, that the built environment and health metrics may not be simply, directly correlated but rather may be correlated through a series of feedback loops that may regulate risk in different ways in different contexts. In particular, evidence for a feedback loop between physical health and destination walking is observed, as well as separate feedback loops between destination walking and objective metrics of the built environment, and destination walking and perception of the built environment. These feedback loops affect the ability to observe how the built environment correlates with residents' physical health. Previous studies have investigated pieces of these associations, but are potentially missing the more complex relationships present. This study proposes a conceptual model describing complex feedback relationships between destination walking and public health, with the built environment expected to increase or decrease the strength of the feedback loop. Evidence supporting these feedback relationships is presented.

  5. Using paleomagnetism to expand the observation time window of plate locking along subduction zones: evidence from the Chilean fore-arc sliver (38°S - 42°S)

    NASA Astrophysics Data System (ADS)

    Hernandez-Moreno, Catalina; Speranza, Fabio; Di Chiara, Anita

    2017-04-01

    Fore-arc crustal motion has been usually addressed by the analysis of earthquake slip vectors and, since the last twenty years, by velocity fields derived from Global Positioning System (GPS) data. Yet this observation time window (few decades) can be significantly shorter than a complete seismic cycle or constrained to interseismic periods where the postseismic deformation release, the vicinity of other important faults, and the slip partitioning in oblique subduction may hinder the finite deformation pattern. Paleomagnetic data may yield finite rotations occurring since rock formation, thus provide a much longer observation time span in the order of millions or tens of millions of years. The cumulative permanent or nonreversing deformation in function of the considered geological formation age can represent the average over many seismic cycles, thus significantly complement "instantaneous" information derived from seismic and GPS data. With the aim of evaluate the strike-variation and evolution of the plate coupling along the Chilean subduction zone, here we report on the paleomagnetism of 43 Oligocene-Pleistocene volcanic sites from the fore-arc sliver between 38°S and 42°S. Sites were gathered west of the 1000 km long Liquiñe-Ofqui dextral fault zone (LOFZ) that represents the eastern fore-arc sliver boundary. Nineteen reliable sites reveal that the fore arc is characterized by counterclockwise (CCW) rotations of variable magnitude, except at 40°S - 41°S, where ultrafast (>50°/Myr) clockwise (CW) rotations occur within a 30 km wide zone adjacent to the LOFZ. CCW rotation variability (even at close sites) and rapidity (>10°/Myr) suggest that the observed block rotation pattern is related to NW-SE seismically active sinistral faults crosscutting the whole fore arc. According to previously published data, CW rotations up to 170° also occur east of the LOFZ and have been related to ongoing LOFZ shear. We suggest that the occurrence and width of the eastern fore-arc sliver undergoing CW rotations is a function of plate coupling along the subduction zone interface. Zones of high coupling enhance stress normal to the LOFZ, induce high LOFZ strength, and yield a wide deformation zone characterized by CW rotations. Conversely, low coupling imply a weak LOFZ, a lack of CW rotations, and a fore arc entirely dominated by CCW rotations related to sinistral fault kinematics. Our locking inferences are in good agreement with those recently derived by GPS analysis and indicate that seismotectonic segment coupling has remained virtually unchanged during the last 5Ma.

  6. Molybdenum mobility and isotopic fractionation during subduction at the Mariana arc

    NASA Astrophysics Data System (ADS)

    Freymuth, Heye; Vils, Flurin; Willbold, Matthias; Taylor, Rex N.; Elliott, Tim

    2015-12-01

    The fate of crustal material recycled into the convecting mantle by plate tectonics is important for understanding the chemical and physical evolution of the planet. Marked isotopic variability of Mo at the Earth's surface offers the promise of providing distinctive signatures of such recycled material. However, characterisation of the behaviour of Mo during subduction is needed to assess the potential of Mo isotope ratios as tracers for global geochemical cycles. Here we present Mo isotope data for input and output components of the archetypical Mariana arc: Mariana arc lavas, sediments from ODP Sites 800, 801 and 802 near the Mariana trench and the altered mafic, oceanic crust (AOC), from ODP Site 801, together with samples of the deeper oceanic crust from ODP Site 1256. We also report new high precision Pb isotope data for the Mariana arc lavas and a dataset of Pb isotope ratios from sediments from ODP Sites 800, 801 and 802. The Mariana arc lavas are enriched in Mo compared to elements of similar incompatibility during upper mantle melting, and have distinct, isotopically heavy Mo (high 98Mo/95Mo) relative to the upper mantle, by up to 0.3 parts per thousand. In contrast, the various subducting sediment lithologies dominantly host isotopically light Mo. Coupled Pb and Mo enrichment in the Mariana arc lavas suggests a common source for these elements and we further use Pb isotopes to identify the origin of the isotopically heavy Mo. We infer that an aqueous fluid component with elevated [Mo], [Pb], high 98Mo/95Mo and unradiogenic Pb is derived from the subducting, mafic oceanic crust. Although the top few hundred metres of the subducting, mafic crust have a high 98Mo/95Mo, as a result of seawater alteration, tightly defined Pb isotope arrays of the Mariana arc lavas extrapolate to a fluid component akin to fresh Pacific mid-ocean ridge basalts. This argues against a flux dominantly derived from the highly altered, uppermost mafic crust or indeed from an Indian-like mantle wedge. Thus we infer that the Pb and Mo budgets of the fluid component are dominated by contributions from the deeper, less altered (cooler) portion of the subducting Pacific crust. The high 98Mo/95Mo of this flux is likely caused by isotopic fractionation during dehydration and fluid flow in the slab. As a result, the residual mafic crust becomes isotopically lighter than the upper mantle from which it was derived. Our results suggest that the continental crust produced by arc magmatism should have an isotopically heavy Mo composition compared to the mantle, whilst a contribution of deep recycled oceanic crust to the sources of some ocean island basalts might be evident from an isotopically light Mo signature.

  7. Geological Development of the Izu-Bonin Forearc Since the Eocene Based on Biostratigraphic, Rock Magnetic, and Sediment Provenance Observations from IODP Expedition 352 Drill Cores

    NASA Astrophysics Data System (ADS)

    Petronotis, K. E.; Robertson, A.; Kutterolf, S.; Avery, A.; Baxter, A.; Schindlbeck, J. C.; Wang, K. L.; Acton, G.

    2016-12-01

    International Ocean Discovery Program (IODP) Expedition 352 recovered early Oligocene to recent sediments above Eocene igneous basement at 4 sites in the Izu-Bonin Forearc. The sites were selected to investigate the forearc region since subduction initiation in the Eocene, with Sites U1439 and U1442 being cored into the upper trench slope and Sites U1440 and U1441 into the lower trench slope. Postcruise studies of biostratigraphy, sediment chemistry, tephra composition and chronology and magnetic properties, along with observations from prior coring help constrain the regional geological development. Volcanic activity in the area, as inferred from its influence on sediment composition, has varied between long periods of activity and quiescence. Combined whole-rock sediment chemistry and tephra compositions suggest that during the Oligocene to earliest Miocene ( 30-22 Ma) tuffaceous input of predominantly dacitic composition was mainly derived from the intra-oceanic Izu-Bonin Arc. The early Miocene interval ( 22-15 Ma) lacks tuffaceous input, as supported by rock magnetic data. During this period, the forearc subsided beneath the carbonate compensation depth (CCD), as evidenced by radiolarian-bearing mud and metal-rich silty clay. This was followed by input of tephra with bimodal felsic and mafic compositions from the Izu-Bonin Arc from 15 to 5 Ma. Middle Miocene to Quaternary time was characterized by increased carbonate preservation, coupled with abundant, predominantly felsic tephra input, which is chemically indicative of a Japan continental arc source (Honshu), with additional chemically distinctive input from the Izu-Bonin Arc. Extending back to 32 Ma, tephra layers can be correlated between the upper-slope sites, extrapolated to the less well-dated lower-slope sites, and further correlated with onland Japanese tephra (Kutterolf et al., 2016; Goldschmidt Conference). Overall, the new results provide an improved understanding of the regional tectonic evolution.

  8. Construction dust amelioration techniques.

    DOT National Transportation Integrated Search

    2012-04-01

    Dust produced on seasonal road construction sites in Alaska is both a traffic safety and environmental concern. Dust emanating from : unpaved road surfaces during construction severely reduces visibility and impacts stopping sight distance, and contr...

  9. Supplement Analysis for the Transmission System Vegetation Management Program FEIS (DOE/EIS-0285/SA-120 Hanford-Ostrander Corridor Maintenance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hutchinson, Ken

    2003-02-10

    Vegetation Management for the Hanford-Ostrander Transmission Line Corridor from Tower 10/4 to Tower 17/2 + 770. The line is a 500kV Single Circuit Transmission Line having an easement width of 300 feet. The proposed work will be accomplished in the indicated sections of the transmission line corridor as referenced on the attached checklist. The work will include the performance of road maintenance and tower pad maintenance along the Hanford-Ostrander transmission line. Maintenance will be performed from Tower 10/1, close to Army Loop road near the northeast corner of 200 West Area of the Hanford Nuclear Reservation to the western edgemore » of the Arid Lands Ecological Reserve (ALE) at Tower 17/2 + 700. Total distance of the work is approximately 7.5 miles. The planned work includes spraying with herbicides to minimize vegetation regrowth along the access roads and removing shrubs from within 50 feet of each transmission tower.« less

  10. E-H mode transition of a high-power inductively coupled plasma torch at atmospheric pressure with a metallic confinement tube

    NASA Astrophysics Data System (ADS)

    Altenberend, Jochen; Chichignoud, Guy; Delannoy, Yves

    2012-08-01

    Inductively coupled plasma torches need high ignition voltages for the E-H mode transition and are therefore difficult to operate. In order to reduce the ignition voltage of an RF plasma torch with a metallic confinement tube the E-H mode transition was studied. A Tesla coil was used to create a spark discharge and the E-H mode transition of the plasma was then filmed using a high-speed camera. The electrical potential of the metallic confinement tube was measured using a high-voltage probe. It was found that an arc between the grounded injector and the metallic confinement tube is maintained by the electric field (E-mode). The transition to H-mode occurred at high magnetic fields when the arc formed a loop. The ignition voltage could be reduced by connecting the metallic confinement tube with a capacitor to the RF generator.

  11. The Physical/Chemical Closed-Loop Life Support Research Project

    NASA Technical Reports Server (NTRS)

    Bilardo, Vincent J., Jr.

    1990-01-01

    The various elements of the Physical/Chemical Closed-Loop Life Support Research Project (P/C CLLS) are described including both those currently funded and those planned for implementation at ARC and other participating NASA field centers. The plan addresses the entire range of regenerative life support for Space Exploration Initiative mission needs, and focuses initially on achieving technology readiness for the Initial Lunar Outpost by 1995-97. Project elements include water reclamation, air revitalization, solid waste management, thermal and systems control, and systems integration. Current analysis estimates that each occupant of a space habitat will require a total of 32 kg/day of supplies to live and operate comfortably, while an ideal P/C CLLS system capable of 100 percent reclamation of air and water, but excluding recycling of solid wastes or foods, will reduce this requirement to 3.4 kg/day.

  12. Water Quality Effects of Forest Roads in Bottomland Hardwood Stands

    Treesearch

    Robert B. Rummer

    1999-01-01

    Management of bottomland hardwood sites requires adequate access to support forest operations. A study conducted in a bottomland forest in central Georgia has evaluated the effect of forest road design on sediment movement and water quality. Five years of measurement indicate that a conventional crowned road design is a net sink for sediment, primarily due to settling...

  13. Predicting forest road surface erosion and storm runoff from high-elevation sites

    Treesearch

    J. M. Grace III

    2017-01-01

    Forest roads are a concern in management because they represent areas of elevated risks associated with soil erosion and storm runoff connectivity to stream systems. Storm runoff emanating from forest roads and their connectivity to downslope resources can be influenced by a myriad of factors, including storm characteristics, management practices, and the interaction...

  14. Overview of approaches to sustain forest productivity during forest road development and timber harvesting activities

    Treesearch

    Charles R. Blinn; Rick Dahlamn; James A. Mattson; Michael A. Thompson

    1999-01-01

    Various approaches are available to minimize impacts on forest productivity during forest road building and timber harvesting activities. These approaches include a variety of practices and technologies. They include practices such as reducing road and trail development, using designated trails, and leaving slash at the stump on nutrient deficient sites. Technology...

  15. Deposition of motor vehicle emissions and winter maintenance along roadside assessed by snow analyses.

    PubMed

    Hautala, E L; Rekilä, R; Tarhanen, J; Ruuskanen, J

    1995-01-01

    A vertical snow-sampling method, where a sample was taken throughout the snowpack, was used to estimate the pollutant load on a roadside where average daily traffic density was about 9100 motor vehicles. The snow samples were collected at two sites, forest and open field, at two distances of 10 and 30 m from the road. The concentrations of inorganic anions (Cl(-), NO(-)(3), SO(2-)(4)), total N, polycyclic aromatic hydrocarbons (PAHs) and polychlorinated phenols (PCPhs) were analysed. The results suggest that on roadsides there is a deposition caused by road traffic emissions and winter maintenance which exceeds normal background deposition. Inorganic anions mainly in particle form, originating from winter maintenance, are deposited near the road. PAHs with low molecular weight (

  16. Alternative Mode of E-Site tRNA Binding in the Presence of a Downstream mRNA Stem Loop at the Entrance Channel.

    PubMed

    Zhang, Yan; Hong, Samuel; Ruangprasert, Ajchareeya; Skiniotis, Georgios; Dunham, Christine M

    2018-03-06

    Structured mRNAs positioned downstream of the ribosomal decoding center alter gene expression by slowing protein synthesis. Here, we solved the cryo-EM structure of the bacterial ribosome bound to an mRNA containing a 3' stem loop that regulates translation. Unexpectedly, the E-site tRNA adopts two distinct orientations. In the first structure, normal interactions with the 50S and 30S E site are observed. However, in the second structure, although the E-site tRNA makes normal interactions with the 50S E site, its anticodon stem loop moves ∼54 Å away from the 30S E site to interact with the 30S head domain and 50S uL5. This position of the E-site tRNA causes the uL1 stalk to adopt a more open conformation that likely represents an intermediate state during E-site tRNA dissociation. These results suggest that structured mRNAs at the entrance channel restrict 30S subunit movement required during translation to slow E-site tRNA dissociation. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. X-ray observations of limb flare loops and post-flare coronal arch

    NASA Technical Reports Server (NTRS)

    Svestka, Zdenek; Smith, Kermit L.; Strong, Keith T.

    1992-01-01

    Postflare arc observations have been obtained following a May 2, 1985 eruptive flare that was detected in X-ray lines above the western solar limb, constituting a rare opportunity for the isolation of pure spectra of the arch without the disturbing effect of X-ray emission from lower and more intense coronal regions. It remains difficult to decide which portion of the observed shift is due to real motion and which is due to cooling, which is faster at lower altitudes.

  18. Determination of use of a real time tone tracker to obtain same beam interferometry data

    NASA Technical Reports Server (NTRS)

    Nandi, S.; Border, J. S.; Folkner, W. M.

    1993-01-01

    The radio metric tracking technique known as Same-Beam Interferometry (SBI) has been shown to improve orbit determination accuracy for the Magellan and Pioneer 12 orbiter. Previous efforts to explore the technique were carried out by making open loop recordings of the carrier signals from the two spacecraft and extracting their phases through post processing. This paper reports on the use of a closed loop receiver to simultaneously measure the carrier signals from two spacecraft in order to produce SBI data in near real time. The Experiment Tone Tracker is a digital closed loop receiver installed in two of NASA's Deep Space Network stations which can simultaneously extract the phase of up to eight tones. The receivers were used in late September and October of 1992 to collect Doppler and SBI data from Pioneer 12 and Magellan. The demise of the Pionner 12 on October 8th during the start-up phase of our tests precluded the collection of an extensive set of SBI data, however two passes of SBI and several arcs of single spacecraft Doppler data were recorded. The SBI data were analyzed and determined to have statistical errors consistent with error models and similar to open loop data.

  19. View of EPA Farm power substation, facing westsouthwest Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of EPA Farm power substation, facing west-southwest - Nevada Test Site, Environmental Protection Agency Farm, Power Substation, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  20. Seerley Road Fire Site

    EPA Pesticide Factsheets

    A barn caught fire at on Seerley Road, Indianapolis. Five storage drums believed to contain metallic potassium were involved in the fire. EPA will perform additional sampling as part of removal operations and safe offsite transportation.

  1. Construction dust amelioration techniques : [executive summary].

    DOT National Transportation Integrated Search

    2012-04-01

    Dust produced on seasonal road construction sites in Alaska is both a traffic safety and environmental concern. Dust emanating from : unpaved road surfaces during construction severely reduces visibility and impacts stopping sight distance, and contr...

  2. Possible costs associated with investigating and mitigating geologic hazards in rural areas of western San Mateo County, California with a section on using the USGS website to determine the cost of developing property for residences in rural parts of San Mateo County, California

    USGS Publications Warehouse

    Brabb, Earl E.; Roberts, Sebastian; Cotton, William R.; Kropp, Alan L.; Wright, Robert H.; Zinn, Erik N.; Digital database by Roberts, Sebastian; Mills, Suzanne K.; Barnes, Jason B.; Marsolek, Joanna E.

    2000-01-01

    This publication consists of a digital map database on a geohazards web site, http://kaibab.wr.usgs.gov/geohazweb/intro.htm, this text, and 43 digital map images available for downloading at this site. The report is stored as several digital files, in ARC export (uncompressed) format for the database, and Postscript and PDF formats for the map images. Several of the source data layers for the images have already been released in other publications by the USGS and are available for downloading on the Internet. These source layers are not included in this digital database, but rather a reference is given for the web site where the data can be found in digital format. The exported ARC coverages and grids lie in UTM zone 10 projection. The pamphlet, which only describes the content and character of the digital map database, is included as Postscript, PDF, and ASCII text files and is also available on paper as USGS Open-File Report 00-127. The full versatility of the spatial database is realized by importing the ARC export files into ARC/INFO or an equivalent GIS. Other GIS packages, including MapInfo and ARCVIEW, can also use the ARC export files. The Postscript map image can be used for viewing or plotting in computer systems with sufficient capacity, and the considerably smaller PDF image files can be viewed or plotted in full or in part from Adobe ACROBAT software running on Macintosh, PC, or UNIX platforms.

  3. Soil Physical, Chemical, and Thermal Characterization, Council Road Site, Seward Peninsula, Alaska, 2016

    DOE Data Explorer

    Alexander Kholodov; David Graham; Ji-Won Moon

    2018-01-22

    This dataset provides the results of physical, chemical, and thermal characterization of soils at the Council Road Site at MM71, Seward Peninsula, Alaska. Soil pits were dug on 11 September 2016 at three sites. This dataset includes field observations and descriptions of soil layers or horizons, field measurements of soil volumetric water content, soil temperature, thermal conductivity, and heat capacity. Laboratory measurements of soil properties include gravimetric water content, bulk density, volumetric water content, total carbon and nitrogen, and elemental composition from X-ray fluorescence for some elements.

  4. Geodetic Survey Coordinates to Support Global Positioning System Tests at Yuma Proving Grounds Arizona

    DTIC Science & Technology

    1975-10-01

    17’ 34V51 DISTANCE 11590.013 m SITE 9 DISC SITE 7 DISC SITE 9 DISC «; TTE 12 DISC 14937.421 m PAD ^,DOME ^ _"_’ - --^CONCRET t...air from either San Diego or Long Beach. To reach the station from the Operations Building at the Naval Undersea Center in Wilson Cove, drive...Operations Building at the Naval Undersea Center In Wilson Cove, drive southeast along the road for about one block. Cross the main road ,jnd proceed south

  5. Accretion of the southern Banda arc to the Australian plate margin determined by Global Positioning System measurements

    NASA Astrophysics Data System (ADS)

    Genrich, Joachim F.; Bock, Yehuda; McCaffrey, Robert; Calais, Eric; Stevens, Colleen W.; Subarya, Cecep

    1996-04-01

    Global Positioning System geodetic measurements at thirteen locations in Indonesia and four in Australia reveal that the Australian continent has accreted the Banda island arc to its margin. Small relative velocities of five sites on west Java, south Kalimantan, Bali, and south Sulawesi define a rigid Sunda shelf that moves relative to northern Australia in a manner consistent with pole locations from NUVEL-1 Australia-Eurasia but at a rate that is about 7% slower. Block-like northward motion of the southern Banda arc toward the Sunda shelf at nearly the same rate as Australia suggests that the Timor trough is now inactive as a thrust. Little of the convergence of Australia with Eurasia is accommodated by strain within the Banda arc structure. Most of the convergence appears to occur as northward translation of the rigid arc with shortening on the Flores and Wetar thrusts and possibly on faults within the back arc basin.

  6. 40Ar/39Ar dating and zircon chronochemistry for the Izu-Bonin rear arc, IODP site U1437

    NASA Astrophysics Data System (ADS)

    Schmitt, A. K.; Konrad, K.; Andrews, G. D.; Horie, K.; Brown, S. R.; Koppers, A. A. P.; Busby, C.; Tamura, Y.

    2016-12-01

    The scientific objective of IODP Expedition 350 drilling at Site U1437 (31°47.390'N, 139°01.580'E) was to reveal the "missing half of the subduction factory": the rear arc of a long-lived intraoceanic subduction zone. Site U1437 lies in a 50 km long and 20 km wide volcano-bounded basin, 90 km west of the Izu arc front, and is the only IODP site drilled in the rear arc. The Izu rear arc is dominated by Miocene basaltic to dacitic seamount chains, which strike at a high angle to the arc front. Radiometric dating targeted a single igneous unit (1390 mbsf), and fine to coarse volcaniclastic units for which we present zircon and 40Ar/39Ar (hornblende, plagioclase, and groundmass) age determinations. All zircons analyzed as grain separates were screened for contamination from drill-mud (Andrews et al., 2016) by analyzing trace elements and, where material was available, O and Hf isotope compositions. Igneous Unit 1 is a rhyolite sheet and yielded concordant in-situ and crystal separate U-Pb zircon ages (13.7±0.3 Ma; MSWD = 1.3; n = 40 spots), whereas the 40Ar/39Ar hornblende plateau age (12.9±0.3; MSWD = 1.1; n = 9 steps) is slightly younger, possibly reflecting pre-eruptive zircon crystallization, or alteration of hornblende. U-Pb zircon and 40Ar/39Ar plateau ages from samples above igneous Unit 1 are concordant with biostratigraphic and paleomagnetic ages (available to 1300 mbsf), but plagioclase and groundmass samples below 1300 m become younger with depth, hinting at post-depositional alteration. A single zircon from 1600 mbsf yielded a U-Pb age of 15.4±1.8 Ma; its trace element composition resembles other igneous zircons from U1437, and is tentatively interpreted as a Middle Miocene age for the lowermost lithostratigraphic unit VII. Oxygen and Hf isotopic values of igneous zircon indicate mantle origins, with some influence of assimilation of hydrothermally altered oceanic crust evident in sub-mantle oxygen isotopic compositions. Lessons from site U1437 are that integrated chronochemistry is essential for achieving accurate age models in oceanic drilling. Reference: Andrews, G. D., Schmitt, A. K., Busby, C. J., Brown, S. R., Blum, P., & Harvey, J. (2016). Age and compositional data of zircon from sepiolite drilling mud to identify contamination of ocean drilling samples. G3. doi: 10.1002/2016GC006397.

  7. Genome Organization Drives Chromosome Fragility.

    PubMed

    Canela, Andres; Maman, Yaakov; Jung, Seolkyoung; Wong, Nancy; Callen, Elsa; Day, Amanda; Kieffer-Kwon, Kyong-Rim; Pekowska, Aleksandra; Zhang, Hongliang; Rao, Suhas S P; Huang, Su-Chen; Mckinnon, Peter J; Aplan, Peter D; Pommier, Yves; Aiden, Erez Lieberman; Casellas, Rafael; Nussenzweig, André

    2017-07-27

    In this study, we show that evolutionarily conserved chromosome loop anchors bound by CCCTC-binding factor (CTCF) and cohesin are vulnerable to DNA double strand breaks (DSBs) mediated by topoisomerase 2B (TOP2B). Polymorphisms in the genome that redistribute CTCF/cohesin occupancy rewire DNA cleavage sites to novel loop anchors. While transcription- and replication-coupled genomic rearrangements have been well documented, we demonstrate that DSBs formed at loop anchors are largely transcription-, replication-, and cell-type-independent. DSBs are continuously formed throughout interphase, are enriched on both sides of strong topological domain borders, and frequently occur at breakpoint clusters commonly translocated in cancer. Thus, loop anchors serve as fragile sites that generate DSBs and chromosomal rearrangements. VIDEO ABSTRACT. Published by Elsevier Inc.

  8. Traveller Information System for Heterogeneous Traffic Condition: A Case Study in Thiruvananthapuram City, India

    NASA Astrophysics Data System (ADS)

    Satyakumar, M.; Anil, R.; Sreeja, G. S.

    2017-12-01

    Traffic in Kerala has been growing at a rate of 10-11% every year, resulting severe congestion especially in urban areas. Because of the limitation of spaces it is not always possible to construct new roads. Road users rely on travel time information for journey planning and route choice decisions, while road system managers are increasingly viewing travel time as an important network performance indicator. More recently Advanced Traveler Information Systems (ATIS) are being developed to provide real-time information to roadway users. For ATIS various methodologies have been developed for dynamic travel time prediction. For this work the Kalman Filter Algorithm was selected for dynamic travel time prediction of different modes. The travel time data collected using handheld GPS device were used for prediction. Congestion Index were calculated and Range of CI values were determined according to the percentage speed drop. After prediction using Kalman Filter, the predicted values along with the GPS data was integrated to GIS and using Network Analysis of ArcGIS the offline route navigation guide was prepared. Using this database a program for route navigation based on travel time was developed. This system will help the travelers with pre-trip information.

  9. Loop-loop interactions govern multiple steps in indole-3-glycerol phosphate synthase catalysis

    PubMed Central

    Zaccardi, Margot J; O'Rourke, Kathleen F; Yezdimer, Eric M; Loggia, Laura J; Woldt, Svenja; Boehr, David D

    2014-01-01

    Substrate binding, product release, and likely chemical catalysis in the tryptophan biosynthetic enzyme indole-3-glycerol phosphate synthase (IGPS) are dependent on the structural dynamics of the β1α1 active-site loop. Statistical coupling analysis and molecular dynamic simulations had previously indicated that covarying residues in the β1α1 and β2α2 loops, corresponding to Arg54 and Asn90, respectively, in the Sulfolobus sulfataricus enzyme (ssIGPS), are likely important for coordinating functional motions of these loops. To test this hypothesis, we characterized site mutants at these positions for changes in catalytic function, protein stability and structural dynamics for the thermophilic ssIGPS enzyme. Although there were only modest changes in the overall steady-state kinetic parameters, solvent viscosity and solvent deuterium kinetic isotope effects indicated that these amino acid substitutions change the identity of the rate-determining step across multiple temperatures. Surprisingly, the N90A substitution had a dramatic effect on the general acid/base catalysis of the dehydration step, as indicated by the loss of the descending limb in the pH rate profile, which we had previously assigned to Lys53 on the β1α1 loop. These changes in enzyme function are accompanied with a quenching of ps-ns and µs-ms timescale motions in the β1α1 loop as measured by nuclear magnetic resonance studies. Altogether, our studies provide structural, dynamic and functional rationales for the coevolution of residues on the β1α1 and β2α2 loops, and highlight the multiple roles that the β1α1 loop plays in IGPS catalysis. Thus, substitution of covarying residues in the active-site β1α1 and β2α2 loops of indole-3-glycerol phosphate synthase results in functional, structural, and dynamic changes, highlighting the multiple roles that the β1α1 loop plays in enzyme catalysis and the importance of regulating the structural dynamics of this loop through noncovalent interactions with nearby structural elements. PMID:24403092

  10. 5. Contextual view of EPA Farm showing holding pens, facing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Contextual view of EPA Farm showing holding pens, facing west-southwest. - Nevada Test Site, Environmental Protection Agency Farm, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  11. View of EPA Farm quonset huts, facing southsouthwest Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of EPA Farm quonset huts, facing south-southwest - Nevada Test Site, Environmental Protection Agency Farm, Quonset Hut Type, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  12. 6. Contextual view of EPA Farm showing cattle shelter, facing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Contextual view of EPA Farm showing cattle shelter, facing southeast. - Nevada Test Site, Environmental Protection Agency Farm, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  13. Interior view, looking northeast in computer room OvertheHorizon Backscatter ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view, looking northeast in computer room - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Five Receiver Building, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  14. Interior view, looking south in computer room OvertheHorizon Backscatter ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view, looking south in computer room - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Six Receiver Building, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  15. Detail of antenna array, looking northnorthwest OvertheHorizon Backscatter Radar ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of antenna array, looking north-northwest - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Five Antenna Array, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  16. General view of Antenna Array, looking west OvertheHorizon Backscatter ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of Antenna Array, looking west - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Six Antenna Array, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  17. Detail of antenna tower structure, looking northnorthwest OvertheHorizon Backscatter ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of antenna tower structure, looking north-northwest - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Five Antenna Array, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  18. 25 CFR 170.110 - How can State and local governments prevent discrimination or adverse impacts?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM Indian Reservation Roads Program Policy and..., trust resources, tribal businesses, religious, and cultural sites; (4) Harming indigenous plants and...

  19. Building No. 1057, Experiment Station Assistant’s Residence, view of north ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Building No. 1057, Experiment Station Assistant’s Residence, view of north elevation - Wind River Administrative Site, Building No. 1057, Chapman Road, near Lookout Mountain Road, Carson, Skamania County, WA

  20. Building No. 1057, Experiment Station Assistant’s Residence, view of west ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Building No. 1057, Experiment Station Assistant’s Residence, view of west elevation - Wind River Administrative Site, Building No. 1057, Chapman Road, near Lookout Mountain Road, Carson, Skamania County, WA

  1. Building No. 1057, Experiment Station Assistant’s Residence, view of east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Building No. 1057, Experiment Station Assistant’s Residence, view of east elevation - Wind River Administrative Site, Building No. 1057, Chapman Road, near Lookout Mountain Road, Carson, Skamania County, WA

  2. Building No. 1057, Experiment Station Assistant’s Residence, view of south ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Building No. 1057, Experiment Station Assistant’s Residence, view of south elevation - Wind River Administrative Site, Building No. 1057, Chapman Road, near Lookout Mountain Road, Carson, Skamania County, WA

  3. Effects of 45 Years of Heavy Road Traffic and Infrastructure on Permafrost and Tundra at Prudhoe Bay, Alaska

    NASA Astrophysics Data System (ADS)

    Walker, D. A.; Buchhorn, M.; Raynolds, M. K.; Kanevskiy, M. Z.; Matyshak, G. V.; Shur, Y.; Peirce, J.

    2015-12-01

    The upper permafrost of the Prudhoe Bay Oilfield, the largest oil field in both the United States and in North America, contains significant amounts of excess ground ice, mainly in ice wedges. An increase in infrastructure development and road traffic since the initial development of the Prudhoe Bay Oilfield in 1968 has resulted in extensive flooding, accumulation of road dust, and roadside snowbanks, all of which affect the vegetation and alter the thermal properties of the ground surface. As part of the NSF's Arctic Science, Engineering, and Education for Sustainability (ArcSEES) project, we established four transects in 2014 and 2015 to document the effects of infrastructure and heavy road traffic on adjacent tundra. Two transects were established perpendicular to the Prudhoe Bay Spine Road north of Lake Colleen and two perpendicular to the Dalton Highway next to the Deadhorse airstrip. Prior to infrastructure development in 1949, rather homogeneous networks of low-centered polygons with less than 30 cm of trough-rim elevation contrast covered both locations. We present the detailed results of vegetation analysis, ice-core drilling, and extensive topographic surveys along the transects. A time series of aerial photographs from 1949 to 2014 (yearly since 1969) documents the changing landscapes in relationship to the record of air-temperature, active layer depths, and permafrost temperatures at Deadhorse. Flooding, road dust, and snow drifts have all contributed to creating warmer soil temperatures and deeper active layers near the road. These factors have all contributed in different ways to alteration of the plant canopy. The altered plant canopies in turn further altered the surface albedo and the ground temperatures. Historical photos indicate that between 1989 and 2012 a regional thawing of the ice-wedges occurred, increasing the extent of thermokarst. Our analysis demonstrates the cumulative effects of infrastructure-related and climate-related factors to these ice-rich permafrost landscapes.

  4. Closed-loop recycling of construction and demolition waste in Germany in view of stricter environmental threshold values.

    PubMed

    Weil, Marcel; Jeske, Udo; Schebek, Liselotte

    2006-06-01

    Recycling of construction and demolition waste contributes decisively to the saving of natural mineral resources. In Germany, processed mineral construction and demolition waste from structural engineering is used nearly exclusively in civil engineering (earthwork and road construction sector) as open-loop recycling. Due to the planned stricter limit values for the protection of soil and water, however, this recycling path in civil engineering may no longer be applicable in the future. According to some new guidelines and standards adopted recently, recycled aggregates may also be used for concrete production in the structural engineering sector (closed-loop recycling). Wastes from the structural engineering sector can thus be kept in a closed cycle, and their disposal on a landfill can be avoided. The present report focuses on the determination of maximum waste volumes that may be handled by this new recycling option. Potential adverse effects on the saving of resources and climate protection have been analysed. For this purpose, materials flow analysis and ecobalancing methods have been used.

  5. A comparative study of standard intensity-modulated radiotherapy and RapidArc planning techniques for ipsilateral and bilateral head and neck irradiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pursley, Jennifer, E-mail: jpursley@mgh.harvard.edu; Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA; Damato, Antonio L.

    The purpose of this study was to investigate class solutions using RapidArc volumetric-modulated arc therapy (VMAT) planning for ipsilateral and bilateral head and neck (H&N) irradiation, and to compare dosimetric results with intensity-modulated radiotherapy (IMRT) plans. A total of 14 patients who received ipsilateral and 10 patients who received bilateral head and neck irradiation were retrospectively replanned with several volumetric-modulated arc therapy techniques. For ipsilateral neck irradiation, the volumetric-modulated arc therapy techniques included two 360° arcs, two 360° arcs with avoidance sectors around the contralateral parotid, two 260° or 270° arcs, and two 210° arcs. For bilateral neck irradiation, themore » volumetric-modulated arc therapy techniques included two 360° arcs, two 360° arcs with avoidance sectors around the shoulders, and 3 arcs. All patients had a sliding-window-delivery intensity-modulated radiotherapy plan that was used as the benchmark for dosimetric comparison. For ipsilateral neck irradiation, a volumetric-modulated arc therapy technique using two 360° arcs with avoidance sectors around the contralateral parotid was dosimetrically comparable to intensity-modulated radiotherapy, with improved conformity (conformity index = 1.22 vs 1.36, p < 0.04) and lower contralateral parotid mean dose (5.6 vs 6.8 Gy, p < 0.03). For bilateral neck irradiation, 3-arc volumetric-modulated arc therapy techniques were dosimetrically comparable to intensity-modulated radiotherapy while also avoiding irradiation through the shoulders. All volumetric-modulated arc therapy techniques required fewer monitor units than sliding-window intensity-modulated radiotherapy to deliver treatment, with an average reduction of 35% for ipsilateral plans and 67% for bilateral plans. Thus, for ipsilateral head and neck irradiation a volumetric-modulated arc therapy technique using two 360° arcs with avoidance sectors around the contralateral parotid is recommended. For bilateral neck irradiation, 2- or 3-arc techniques are dosimetrically comparable to intensity-modulated radiotherapy, but more work is needed to determine the optimal approaches by disease site.« less

  6. A comparative study of standard intensity-modulated radiotherapy and RapidArc planning techniques for ipsilateral and bilateral head and neck irradiation.

    PubMed

    Pursley, Jennifer; Damato, Antonio L; Czerminska, Maria A; Margalit, Danielle N; Sher, David J; Tishler, Roy B

    2017-01-01

    The purpose of this study was to investigate class solutions using RapidArc volumetric-modulated arc therapy (VMAT) planning for ipsilateral and bilateral head and neck (H&N) irradiation, and to compare dosimetric results with intensity-modulated radiotherapy (IMRT) plans. A total of 14 patients who received ipsilateral and 10 patients who received bilateral head and neck irradiation were retrospectively replanned with several volumetric-modulated arc therapy techniques. For ipsilateral neck irradiation, the volumetric-modulated arc therapy techniques included two 360° arcs, two 360° arcs with avoidance sectors around the contralateral parotid, two 260° or 270° arcs, and two 210° arcs. For bilateral neck irradiation, the volumetric-modulated arc therapy techniques included two 360° arcs, two 360° arcs with avoidance sectors around the shoulders, and 3 arcs. All patients had a sliding-window-delivery intensity-modulated radiotherapy plan that was used as the benchmark for dosimetric comparison. For ipsilateral neck irradiation, a volumetric-modulated arc therapy technique using two 360° arcs with avoidance sectors around the contralateral parotid was dosimetrically comparable to intensity-modulated radiotherapy, with improved conformity (conformity index = 1.22 vs 1.36, p < 0.04) and lower contralateral parotid mean dose (5.6 vs 6.8Gy, p < 0.03). For bilateral neck irradiation, 3-arc volumetric-modulated arc therapy techniques were dosimetrically comparable to intensity-modulated radiotherapy while also avoiding irradiation through the shoulders. All volumetric-modulated arc therapy techniques required fewer monitor units than sliding-window intensity-modulated radiotherapy to deliver treatment, with an average reduction of 35% for ipsilateral plans and 67% for bilateral plans. Thus, for ipsilateral head and neck irradiation a volumetric-modulated arc therapy technique using two 360° arcs with avoidance sectors around the contralateral parotid is recommended. For bilateral neck irradiation, 2- or 3-arc techniques are dosimetrically comparable to intensity-modulated radiotherapy, but more work is needed to determine the optimal approaches by disease site. Copyright © 2017 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.

  7. A STUDY ON PREPARING THE BCP FOR LOCAL ADMINISTRATION COSIDERING SUBSISTED RISK ANALYSIS OF ROAD NETWORK

    NASA Astrophysics Data System (ADS)

    Sakata, Akio; Ito, Norio; Kawamoto, Atsushi; Shiraki, Wataru

    For road networks in mountain site which are very important infrastructures for rescue and support operations in disaster, a study on preparing the BCP for local administrations at less favored area considering subsisted risk analysis is performed. As a risk the stop of road networks caused by collapse of natural slop or cut slop is considered. The effects of the stop of road networks are analyzed and the important of preparing the BCP is demonstrated.

  8. 75 FR 33761 - Notice of a New Fee Site; Federal Lands Recreation Enhancement Act (Title VIII, Pub. L. 108-447)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... $5.00 daily user fee or accept the $20 annual user vehicle sticker at the Beck Road Trailhead based... Beck Road Trailhead on the Chequamegon-Nicolet National Forest will provide a much needed trailhead... communities of Drummond, Barnes, Cable, Delta, and Iron River. The funds collected at the Beck Road Trailhead...

  9. Affects of road sign wording on visitor survey - non-response bias

    Treesearch

    Susan M. Kocis; Stanley J. Zarnoch; Donald B.K. English

    2004-01-01

    On-site visitor interviewer data collection is a key component of the USDA Forest Service National Visitor Use Monitoring (NVUM) program. In many areas, especially higher speed roads and roads with non-recreation traffic, many vehicles may not stop for an interview. Wording on the sign may condition non-recreation visitors to self-select as to whether or not they...

  10. Evaluation of Geotextile Reinforced Embankments on the Farmer’s Loop Road in Fairbanks, Alaska

    DTIC Science & Technology

    1986-06-01

    0762 .0000 .2022 I1 20 -. 006 .00O6: .0000 -,1176 - 1276 . 0000 .210 .20 " ..... ’ .666 ....... :2" bbd ......... d646 ..... 1. 7. 6...4.212 ŕ 346 4.3 7 蕔| 1.11 42 ....... ’....... 2. ,f’ .... - Td " f o’ ’ - .. ... . .... 47 I 4.: .0 .461 - ;10 048 .41 211 - 271 .4 0 47 48 221.0

  11. How Does Decommissioning Forest Roads Effect Hydrologic and Geomorphic Risk?

    NASA Astrophysics Data System (ADS)

    Black, T.; Luce, C.; Cissel, R. M.; Nelson, N.; Staab, B.

    2010-12-01

    The US Forest Service is investigating road decommissioning projects to understand how treatments change hydrologic and geomorphic risks. Road treatment effect was measured using a before after control impact design (BACI), using the Geomorphic Road Analysis and Inventory Package (http://www.fs.fed.us/GRAIP). This suite of inventory and analysis tools evaluates: road-stream hydrologic connectivity, fine sediment production and delivery, shallow landslide risk, gully initiation risk, and risks associated with stream crossing failures. The Skokomish River study site is steep and wet and received a high intensity treatment including the removal of stream crossing pipes and fills, all ditch relief pipes and a full hillslope recontouring. Road to stream hydrologic connectivity was reduced by 70%. The treatments reduced fine sediment delivery by 21.8 tons or 81%. The removal of the stream crossing culverts and large associated road fills eliminated the risk of pipe plugging related failures and the eventual erosion of over 4,000 m3 of fill. The slope stability risk was assessed using a modified version of SINMAP (Pack et al, 2005). Risk below drain point locations on the original road was reduced as water was redistributed across the hillslope to waterbars and diffuse drainage. It is unclear; however, if landslide risk was reduced across the entire treated road length because treatments slightly increased risk in some areas where new concentrated drainage features were added above steep slopes. Similarly, values of a gully index ESI (Istanbulluoglu et al, 2003), were reduced at many of the original drainage points, however some new drainage was added. ESI values still exceed a predicted conservative initiation thresholds at some sites, therefore it is uncertain if gully risk will be changed. Mann Creek occupies a moderately steep mid-elevation site in Southern Idaho. The high intensity treatments removed all constructed road drainage features including stream crossing pipes and fills, and recontoured the hillslope. The length of road that was hydrologically connected to streams was reduced by 2,923 m, or 97%. The model predicts that fine sediment delivery was reduced by 98%, to 1.0 ton annually. The risk presented by stream crossings becoming plugged was eliminated. The potential for streamflow diversion onto roads and hillslopes was precluded. The slope stability risk below drain point locations on the original road was reduced as water was no longer concentrated and discharged through a single drainage feature. Treatments are predicted to return slope stability to near undisturbed levels. Gully initiation risks, already low prior to treatment, may be reduced to negligible values. Results from these two case studies suggest that high intensity road decommissioning can be effective at reducing the risk of road sediment delivery, hydrologic connectivity and failures associated with stream crossings. Post storm monitoring will help validate these predictions and reduce uncertainty around the hydrology of decommissioned roads. If decommissioned roads continue to concentrate water and discharge it onto steep slopes, landslides and gully risk may remain elevated.

  12. A theoretical analysis of vacuum arc thruster performance

    NASA Technical Reports Server (NTRS)

    Polk, James E.; Sekerak, Mike; Ziemer, John K.; Schein, Jochen; Qi, Niansheng; Binder, Robert; Anders, Andre

    2001-01-01

    In vacuum arc discharges the current is conducted through vapor evaporated from the cathode surface. In these devices very dense, highly ionized plasmas can be created from any metallic or conducting solid used as the cathode. This paper describes theoretical models of performance for several thruster configurations which use vacuum arc plasma sources. This analysis suggests that thrusters using vacuum arc sources can be operated efficiently with a range of propellant options that gives great flexibility in specific impulse. In addition, the efficiency of plasma production in these devices appears to be largely independent of scale because the metal vapor is ionized within a few microns of the cathode electron emission sites, so this approach is well-suited for micropropulsion.

  13. Selection of den sites by black bears in the southern Appalachians

    USGS Publications Warehouse

    Reynolds-Hogland, M. J.; Mitchell, M.S.; Powell, R.A.; Brown, D.C.

    2007-01-01

    We evaluated selection of den sites by American black bears (Ursus americanus) in the Pisgah Bear Sanctuary, western North Carolina, by comparing characteristics of dens at 53 den sites with availability of habitat characteristics in annual home ranges of bears and in the study area. We also tested whether den-site selection differed by sex, age, and reproductive status of bears. In addition, we evaluated whether the den component of an existing habitat model for black bears predicted where bears would select den sites. We found bears selected den sites far from gravel roads, on steep slopes, and at high elevations relative to what was available in both annual home ranges and in the study area. Den-site selection did not differ by sex or age, but it differed by reproductive status. Adult females with cubs preferred to den in areas that were relatively far from gravel roads, but adult females without cubs did not. The habitat model overestimated the value of areas near gravel roads, underestimated the value of moderately steep areas, and did not include elevation as a predictor variable. Our results highlight the importance of evaluating den selection in terms of both use and availability of den characteristics. ?? 2007 American Society of Mammalogists.

  14. When roads appear jaguars decline: Increased access to an Amazonian wilderness area reduces potential for jaguar conservation

    PubMed Central

    Celis, Gerardo; Branch, Lyn C.

    2018-01-01

    Roads are a main threat to biodiversity conservation in the Amazon, in part, because roads increase access for hunters. We examine how increased landscape access by hunters may lead to cascading effects that influence the prey community and abundance of the jaguar (Panthera onca), the top Amazonian terrestrial predator. Understanding such ecological effects originating from anthropogenic actions is essential for conservation and management of wildlife populations in areas undergoing infrastructure development. Our study was conducted in Yasuní Biosphere Reserve, the protected area with highest potential for jaguar conservation in Ecuador, and an area both threatened by road development and inhabited by indigenous groups dependent upon bushmeat. We surveyed prey and jaguar abundance with camera traps in four sites that differed in accessibility to hunters and used site occupancy and spatially explicit capture-recapture analyses to evaluate prey occurrence and estimate jaguar density, respectively. Higher landscape accessibility to hunters was linked with lower occurrence and biomass of game, particularly white-lipped peccary (Tayassu pecari) and collared peccary (Pecari tajacu), the primary game for hunters and prey for jaguars. Jaguar density was up to 18 times higher in the most remote site compared to the most accessible site. Our results provide a strong case for the need to: 1) consider conservation of large carnivores and other wildlife in policies about road construction in protected areas, 2) coordinate conservation initiatives with local governments so that development activities do not conflict with conservation objectives, and 3) promote development of community-based strategies for wildlife management that account for the needs of large carnivores. PMID:29298311

  15. When roads appear jaguars decline: Increased access to an Amazonian wilderness area reduces potential for jaguar conservation.

    PubMed

    Espinosa, Santiago; Celis, Gerardo; Branch, Lyn C

    2018-01-01

    Roads are a main threat to biodiversity conservation in the Amazon, in part, because roads increase access for hunters. We examine how increased landscape access by hunters may lead to cascading effects that influence the prey community and abundance of the jaguar (Panthera onca), the top Amazonian terrestrial predator. Understanding such ecological effects originating from anthropogenic actions is essential for conservation and management of wildlife populations in areas undergoing infrastructure development. Our study was conducted in Yasuní Biosphere Reserve, the protected area with highest potential for jaguar conservation in Ecuador, and an area both threatened by road development and inhabited by indigenous groups dependent upon bushmeat. We surveyed prey and jaguar abundance with camera traps in four sites that differed in accessibility to hunters and used site occupancy and spatially explicit capture-recapture analyses to evaluate prey occurrence and estimate jaguar density, respectively. Higher landscape accessibility to hunters was linked with lower occurrence and biomass of game, particularly white-lipped peccary (Tayassu pecari) and collared peccary (Pecari tajacu), the primary game for hunters and prey for jaguars. Jaguar density was up to 18 times higher in the most remote site compared to the most accessible site. Our results provide a strong case for the need to: 1) consider conservation of large carnivores and other wildlife in policies about road construction in protected areas, 2) coordinate conservation initiatives with local governments so that development activities do not conflict with conservation objectives, and 3) promote development of community-based strategies for wildlife management that account for the needs of large carnivores.

  16. Analysis of multi-temporal landsat satellite images for monitoring land surface temperature of municipal solid waste disposal sites.

    PubMed

    Yan, Wai Yeung; Mahendrarajah, Prathees; Shaker, Ahmed; Faisal, Kamil; Luong, Robin; Al-Ahmad, Mohamed

    2014-12-01

    This studypresents a remote sensing application of using time series Landsat satellite images for monitoring the Trail Road and Nepean municipal solid waste (MSW) disposal sites in Ottawa, Ontario, Canada. Currently, the Trail Road landfill is in operation; however, during the 1960s and 1980s, the city relied heavily on the Nepean landfill. More than 400 Landsat satellite images were acquired from the US Geological Survey (USGS) data archive between 1984 and 2011. Atmospheric correction was conducted on the Landsat images in order to derive the landfill sites' land surface temperature (LST). The findings unveil that the average LST of the landfill was always higher than the immediate surrounding vegetation and air temperature by 4 to 10 °C and 5 to 11.5 °C, respectively. During the summer, higher differences of LST between the landfill and its immediate surrounding vegetation were apparent, while minima were mostly found in fall. Furthermore, there was no significant temperature difference between the Nepean landfill (closed) and the Trail Road landfill (active) from 1984 to 2007. Nevertheless, the LST of the Trail Road landfill was much higher than the Nepean by 15 to 20 °C after 2007. This is mainly due to the construction and dumping activities (which were found to be active within the past few years) associated with the expansion of the Trail Road landfill. The study demonstrates that the use of the Landsat data archive can provide additional and viable information for the aid of MSW disposal site monitoring.

  17. Predicting a roadkill hotspots based on spatial distribution of Korean water deer (Hydropotes inermis argyropus) using Maxent model in South Korea Expressway : In Case of Cheongju-Sangju Expressway

    NASA Astrophysics Data System (ADS)

    Park, Hyomin; Lee, Sangdon

    2016-04-01

    Road construction has direct and indirect effects on ecosystems. Especially wildlife-vehicle conflicts (roadkills) caused by roads are a considerable threat for population of many species. This study aims to identify the effects of topographic characteristics and spatial distribution of Korean water deer (Hydropotes inermis). Korean water deer is indigenous and native species in Korea that listed LC (least concern) by IUCN redlist categories. Korean water deer population is growing every year occupying for most of roadkills (>70%) in Korean express highway. In order to predict a distribution of the Korean water deer, we selected factors that most affected water deer's habitat. Major habitats of waterdeer are known as agricultural area, forest area and water. Based on this result, eight factors were selected (land cover map, vegetation map, age class of forest, diameter class of tree, population, slope of study site, elevation of study site, distance of river), and made a thematic map by using GIS program (ESRI, Arc GIS 10.3.1 ver.). To analyze the affected factors of waterdeer distribution, GPS data and thematic map of study area were entered into Maxent model (Maxent 3.3.3.k.). Results of analysis were verified by the AUC (Area Unit Curve) of ROC (Receiver Operating Characteristic). The ROC curve used the sensitivity and specificity as a reference for determining the prediction efficiency of the model and AUC area of ROC curve was higher prediction efficiency closer to '1.' Selecting factors that affected the distribution of waterdeer were land cover map, diameter class of tree and elevation of study site. The value of AUC was 0.623. To predict the water deer's roadkills hot spot on Cheongju-Sangju Expressway, the thematic map was prepared based on GPS data of roadkill spots. As a result, the topographic factors that affected waterdeer roadkill were land cover map, actual vegetation map and age class of forest and the value of AUC was 0.854. Through this study, we could identify the site and hot spots that water deer frequently expected to use based on quantitative data on the spatial and topographic factors. Therefore, we can suggest ways to minimize roadkills by selecting the hot spots and by suggesting construction of eco-corridors. This study will significantly enhance human-wildlife conflicts by identifying key habitat areas for wild mammals.

  18. Closeup view of EPA Farm cattle shelter lamp, facing west ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view of EPA Farm cattle shelter lamp, facing west - Nevada Test Site, Environmental Protection Agency Farm, Shelter Unit Type, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  19. View of EPA Farm cattle shelter (featuring horse trailer), facing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of EPA Farm cattle shelter (featuring horse trailer), facing northwest - Nevada Test Site, Environmental Protection Agency Farm, Shelter Unit Type, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  20. 1. View of EPA Farm Lab Building 1506, facing south ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View of EPA Farm Lab Building 15-06, facing south - Nevada Test Site, Environmental Protection Agency Farm, Laboratory Building, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  1. 4. Contextual view of EPA Farm showing radwaste tank, facing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Contextual view of EPA Farm showing rad-waste tank, facing south-southeast. - Nevada Test Site, Environmental Protection Agency Farm, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  2. 2. Contextual view of EPA Farm showing milliongallon reservoir, facing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Contextual view of EPA Farm showing million-gallon reservoir, facing east-southeast. - Nevada Test Site, Environmental Protection Agency Farm, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  3. General view of Antenna Array and building complex, looking northeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of Antenna Array and building complex, looking northeast - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Six Antenna Array, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  4. General view of Antenna Array and building complex, looking southwest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of Antenna Array and building complex, looking southwest - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Six Antenna Array, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  5. 3. View of Japanese village, type C structure, facing eastsoutheast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. View of Japanese village, type C structure, facing east-southeast - Nevada Test Site, Japanese Village, Type C Structure, Area 4, Yucca Flat, 4-04 Road near Rainier Mesa Road, Mercury, Nye County, NV

  6. 7. VIEW OF BOOSTER STATION 3, FACING NORTHWEST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. VIEW OF BOOSTER STATION 3, FACING NORTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  7. 2. VIEW OF BOOSTER STATION 1, FACING NORTHEAST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW OF BOOSTER STATION 1, FACING NORTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  8. 11. VIEW OF BOOSTER STATION 4, FACING SOUTHEAST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. VIEW OF BOOSTER STATION 4, FACING SOUTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  9. 10. VIEW OF BOOSTER STATION 4, FACING NORTHWEST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. VIEW OF BOOSTER STATION 4, FACING NORTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  10. 1. VIEW OF BOOSTER STATION 1, FACING SOUTHWEST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW OF BOOSTER STATION 1, FACING SOUTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  11. 8. VIEW OF BOOSTER STATION 3, FACING SOUTHEAST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF BOOSTER STATION 3, FACING SOUTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  12. 4. VIEW OF BOOSTER STATION 2, FACING NORTHWEST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. VIEW OF BOOSTER STATION 2, FACING NORTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  13. 5. VIEW OF BOOSTER STATION 2, FACING SOUTHEAST Nevada ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. VIEW OF BOOSTER STATION 2, FACING SOUTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

  14. 24 CFR 9.103 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... maintenance, re-roofing, painting, or wallpapering or changes to mechanical and electrical systems are not... buildings, structures, site improvements, complexes, equipment, roads, walks, passageways, parking lots... whole of one or more residential structures and appurtenant structures, equipment, roads, walks, and...

  15. 24 CFR 9.103 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... maintenance, re-roofing, painting, or wallpapering or changes to mechanical and electrical systems are not... buildings, structures, site improvements, complexes, equipment, roads, walks, passageways, parking lots... whole of one or more residential structures and appurtenant structures, equipment, roads, walks, and...

  16. 24 CFR 9.103 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... maintenance, re-roofing, painting, or wallpapering or changes to mechanical and electrical systems are not... buildings, structures, site improvements, complexes, equipment, roads, walks, passageways, parking lots... whole of one or more residential structures and appurtenant structures, equipment, roads, walks, and...

  17. View of EPA Farm storage shed, facing north. Greenhouse is ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of EPA Farm storage shed, facing north. Greenhouse is in background - Nevada Test Site, Environmental Protection Agency Farm, Storage Shed, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  18. A New Sliding-Loop Technique in Renorrhaphy for Partial Nephrectomy: A Feasibility Study in a Porcine Model.

    PubMed

    Lee, Jung Keun; Oh, Jong Jin; Lee, Sangchul; Lee, Seung Bae; Byun, Seok-Soo; Lee, Sang Eun; Jeong, Chang Wook

    2016-04-01

    We developed a sliding-loop technique that narrowed both sides of the parenchyma in a porcine model and compared it with the conventional sliding-clip technique. Three pigs (30-40 kg) were reused following another experiment conducted by the same researchers. Bilateral kidneys were harvested within 30 minutes after euthanasia. Two partial nephrectomies per kidney were performed on opposite surfaces. All kidney defects were of the same size (diameter of 2.5-3 cm with a depth of 1.0-1.5 cm). The sliding-clip technique and sliding-loop technique were performed separately. In the sliding-loop technique, we created a 1-cm loop at the end of a Vicryl and placed a tetrafluoroethylene polymer pledget in front of the knots passing through the needle. The needle then crossed the loop after passing through the renal parenchyma. A Weck clip was placed and slid on one side to tighten the suture. Tightening was controlled with an equivalent force using a digital push-pull gauge. Three stitches were placed at each renorrhaphy site. The distance between repaired renal surfaces was measured at 5 different points (3 suture sites and 2 middle sites between sutures). The results of the 2 techniques were compared by using the independent t test. The mean distance between renal surfaces was significantly narrower in the sliding-loop technique than in the conventional technique (1.80 ± 1.08 mm vs 5.28 ± 2.46 mm, P < .001). In the porcine model, the sliding-loop technique more effectively closed the partial nephrectomy defects compared with the conventional sliding-clip technique. © The Author(s) 2015.

  19. Water resources of Monroe County, New York, water years 1989-93, with emphasis on water quality in the Irondequoit Creek Basin; Part 2, Atmospheric deposition, ground water, streamflow, trends in water quality, and chemical loads to Irondequoit Bay

    USGS Publications Warehouse

    Sherwood, Donald A.

    1999-01-01

    Irondequoit Creek, which drains 169 square miles in the eastern part of Monroe County, has been recognized as a source of contaminants that contribute to the eutrophication of Irondequoit Bay on Lake Ontario. The discharge from sewage-treatment plants to the creek and its tributaries was eliminated in 1979 by diversion to another wastewater-treatment facility, but sediment and nonpoint-source pollution remain a concern. This report presents data from five surface-water sites in the Irondequoit Creek basin. Irondequoit Creek at Railroad Mills, East Branch Allen Creek, Allen Creek near Rochester, Irondequoit Creek at Blossom Road, and Irondequoit Creek at Empire Boulevard, to supplement published data from 1984-88. Data from Northrup Creek, which drains 11.7 square miles in western Monroe County, provide information on surface-water quality west of the Genesee River. Also presented are water-level and water-quality data from 12 observation-well sites in Ellison and Powdermill Parks and atmospheric-deposition data from 1 site (Mendon Ponds). Concentrations of several chemical constituents in streams of the Irondequoit Creek basin showed statistically significant trends during 1989-93. Concentrations of total suspended-solids and volatile suspended-solids in Irondequoit Creek at Blossom Road decreased 13.5 and 12.5 percent per year, respectively, and those at Empire Boulevard decreased 33.5 and 22 percent per year, respectively. Concentrations of ammonia plus organic nitrogen increased 17.6 percent per year at one site in the basin, but decreased 8.5 and 22.3 percent per year at two sites. Nitrite plus nitrate decreased at only one site (3.5 percent per year). Concentrations of total phosphorus increased at two sites (about 7 percent per year) and decreased at two other sites (7.6 and 29.9 percent per year), and orthophosphate concentrations increased at one site (10.8 percent per year). Dissolved chloride increased at three sites (1.7 to 10.9 percent per year), and dissolved sulfate decreased at one site (2.1 percent per year) and increased at one site (6.8 percent per year). Median concentrations of constituents were significantly lower in atmospheric deposition than in streamflow, although annual deposition of ammonia nitrogen, nitrite plus nitrate, total phosphorus, and orthophosphate in the basin exceeded the amounts removed by streamflow. Atmospheric deposition of chloride and sulfate, by contrast, represented only 1 and 12 percent, respectively, of the loads transported by Irondequoit Creek (Blossom Road site). Comparison of water-quality data from the Allen Creek site and Irondequoit Creek at Blossom Road from water years 1989-93 with corresponding data from 1984-88 indicates significant changes in median concentrations of several constituents. The concentration of dissolved chloride increased at Blossom Road and was unchanged at Allen Creek, whereas sulfate decreased at both sites. Concentrations of ammonia plus organic nitrogen, and nitrite plus nitrate, were significantly lower during 1989-93 than during 1984-88 at both sites. Total phosphorus concentration was lower during 1984-88 than during 1989-93 at Blossom Road but showed no change at Allen Creek, and orthophosphate concentration for 1989-93 was lower than in 1984-88 at both sites. Comparison of chemical loads in atmospheric deposition also indicates significant changes in many constituents. Five-year-mean loads of sodium, sulfate, and lead in atmospheric deposition for 1989-93 exceeded those for 1984-88, whereas 5-year-mean loads of calcium, magnesium, potassium, chloride, nitrite plus nitrate, ammonia nitrogen, and orthophosphate for 1989-93 were lower than in 1984-88. The changes in surface-water quality resulted from several factors within the basin, including land-use changes, annual and seasonal variations in streamflow, and year-to-year variations in the application of deicing salts on area roads. Statistical analyses of long-term (9 years or more) flow rec

  20. Seed spillage from grain trailers on road verges during oilseed rape harvest: an experimental survey.

    PubMed

    Bailleul, Diane; Ollier, Sébastien; Huet, Sylvie; Gardarin, Antoine; Lecomte, Jane

    2012-01-01

    Anthropogenic vectors enhance the natural dispersal capacity of plant seeds significantly in terms of quantity and distance. Human-mediated seed dispersal (i.e. anthropochory) greatly increases the dispersal of crop species across agroecosystems. In the case of oilseed rape (OSR), spillage of seeds from grain trailers during harvest has never been quantified. Our experimental approach involved establishing 85 seed trap-sites on the road verges of an agricultural area around the grain silo of Selommes (Loir-et-Cher, France). We recorded OSR spillage during harvest and applied a linear model to the data. The amount of seed spilled was related positively to the area of the OSR fields served by the road, whereas the amount of seed spilled decreased with other variables, such as distance from the trap-site to the verge of the road and to the nearest field. The distance to the grain silo, through local and regional effects, affected seed loss. Local effects from fields adjacent to the road resulted in a cumulative spillage on one-lane roads. On two-lane roads, spillage was nearly constant whatever the distance to the silo due to a mixture of these local effects and of grain trailers that joined the road from more distant fields. From the data, we predicted the number of seeds lost from grain trailers on one road verge in the study area. We predicted a total spillage of 2.05 × 10(6) seeds (± 4.76 × 10(5)) along the road length, which represented a mean of 404 ± 94 seeds per m(2). Containment of OSR seeds will always be challenging. However, seed spillage could be reduced if grain trailers were covered and filled with less seed. Reducing distances travelled between fields and silos could also limit seed loss.

  1. Distance from roads and cities as a predictor of habitat loss and fragmentation in the caatinga vegetation of Brazil.

    PubMed

    Santos, A M; Tabarelli, M

    2002-11-01

    Roads and cities represent huge sources of degradation for adjacent ecosystems regarding nutrient cycling, energy, water flow and species composition. In this study we test the hypothesis that distance from roads and cities is associated with habitat loss and fragmentation in the caatinga vegetation--a dry forest to scrub vegetation that covers ca. 736,000 km2 of northeast Brazil. The study site comprised a 2,828.8 km2 piece (64 km x 44.2 km) of Xingó region (09 degrees 36'S, 37 degrees 50'W), which is located between the States of Alagoas and Sergipe. Based on satellite imagery we mapped the remaining vegetation, 145 km of paved roads and the seven small-sized cities set in the study site. A positive correlation was found between the combined distance from roads and cities and the percentage of remaining vegetation as it dropped from 18% at 12 km distant to 5.9% at 1 km distant from cities and roads. Thus, remaining vegetation was reduced by one third near cities and roads. A positive correlation was also found between distance from cities and roads and the percentage of fragments larger than 200 ha, which ranged from 3.6% (within 3 km distance class) to 23.3% (15 km distance class) of all fragments. Our results suggest a road/city-effect zone of 12 to 15 km width, over which habitat loss and fragmentation extend throughout the caatinga vegetation. These findings should be considered in the regional polices for biodiversity conservation and economic development of the caatinga region.

  2. 14. Photographic copy of photograph, dated 21 July 1971 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photographic copy of photograph, dated 21 July 1971 (original print in possession of U.S. Space & Strategic Defense Command Historic Office CSSD-HO, Huntsville, AL). Photographer unknown. View of missile site control building turret wall during early construction, illustrating the massive amount of rebar utilized in the project. - Stanley R. Mickelsen Safeguard Complex, Missile Site Control Building, Northeast of Tactical Road; southeast of Tactical Road South, Nekoma, Cavalier County, ND

  3. Spectral-analysis-based extraction of land disturbances arising from oil and gas development in diverse landscapes

    NASA Astrophysics Data System (ADS)

    Zhang, Ying; Lantz, Nicholas; Guindon, Bert; Jiao, Xianfen

    2017-01-01

    Accurate and frequent monitoring of land surface changes arising from oil and gas exploration and extraction is a key requirement for the responsible and sustainable development of these resources. Petroleum deposits typically extend over large geographic regions but much of the infrastructure required for oil and gas recovery takes the form of numerous small-scale features (e.g., well sites, access roads, etc.) scattered over the landscape. Increasing exploitation of oil and gas deposits will increase the presence of these disturbances in heavily populated regions. An object-based approach is proposed to utilize RapidEye satellite imagery to delineate well sites and related access roads in diverse complex landscapes, where land surface changes also arise from other human activities, such as forest logging and agriculture. A simplified object-based change vector approach, adaptable to operational use, is introduced to identify the disturbances on land based on red-green spectral response and spatial attributes of candidate object size and proximity to roads. Testing of the techniques has been undertaken with RapidEye multitemporal imagery in two test sites located at Alberta, Canada: one was a predominant natural forest landscape and the other landscape dominated by intensive agricultural activities. Accuracies of 84% and 73%, respectively, have been achieved for the identification of well site and access road infrastructure of the two sites based on fully automated processing. Limited manual relabeling of selected image segments can improve these accuracies to 95%.

  4. Coupling between Catalytic Loop Motions and Enzyme Global Dynamics

    PubMed Central

    Kurkcuoglu, Zeynep; Bakan, Ahmet; Kocaman, Duygu; Bahar, Ivet; Doruker, Pemra

    2012-01-01

    Catalytic loop motions facilitate substrate recognition and binding in many enzymes. While these motions appear to be highly flexible, their functional significance suggests that structure-encoded preferences may play a role in selecting particular mechanisms of motions. We performed an extensive study on a set of enzymes to assess whether the collective/global dynamics, as predicted by elastic network models (ENMs), facilitates or even defines the local motions undergone by functional loops. Our dataset includes a total of 117 crystal structures for ten enzymes of different sizes and oligomerization states. Each enzyme contains a specific functional/catalytic loop (10–21 residues long) that closes over the active site during catalysis. Principal component analysis (PCA) of the available crystal structures (including apo and ligand-bound forms) for each enzyme revealed the dominant conformational changes taking place in these loops upon substrate binding. These experimentally observed loop reconfigurations are shown to be predominantly driven by energetically favored modes of motion intrinsically accessible to the enzyme in the absence of its substrate. The analysis suggests that robust global modes cooperatively defined by the overall enzyme architecture also entail local components that assist in suitable opening/closure of the catalytic loop over the active site. PMID:23028297

  5. Hydrothermal vent community zonation along environmental gradients at the Lau back-arc spreading center

    NASA Astrophysics Data System (ADS)

    Kim, Stacy; Hammerstrom, Kamille

    2012-04-01

    The Lau back-arc spreading center exhibits gradients in hydrothermal vent habitat characteristics from north to south. Biological zonation within a few meters of vents has been described as temperature driven. We constructed georeferenced photomosaics of the seafloor out to tens of meters beyond vents to describe peripheral zonation and explore correlations between environmental conditions and the biological community. Cluster analysis separated northern sites from southern sites, corresponding to a break in substrate from basalt in the north to andesite in the south. Northern sites were dominated by anemones, and southern by sponges. A previous suggestion that dominants may be dependent on friability of the substrate was not supported; when visually distinguishable, individual species within taxa showed different patterns. Northern sites hosted proportionally more suspension feeding species. Sulfide that can support microbial food sources is at higher concentrations at these sites, though bathymetry that may enhance bottom currents is less rugged. Northern sites had higher diversity that may result from the overall northwards flow, which would generally permit easier dispersal downcurrent, though we observed no difference in dispersal strategies at different sites.

  6. Crustal evolution of Eocene paleo arc around Ogasawara region obtained by seismic reflection survey

    NASA Astrophysics Data System (ADS)

    Yamashita, M.; Takahashi, N.; Kodaira, S.; Miura, S.; Ishizuka, O.; Tatsumi, Y.

    2011-12-01

    The Izu-Bonin (Ogasawara)-Mariana (IBM) arc is known to the typical oceanic island arc, and it is the most suitable area to understand the growth process of island arc. The existence of two paleo arc which consists of Oligocene and Eocene paleo age is known in IBM forearc region by geological and geophysical studies. The Ogasawara ridge is also known to locate the initial structure of arc evolution from geologic sampling of research submersible. In this region, IODP drilling site: IBM-2 is proposed in order to understand the temporal and spatial change in arc crust composition from 50 to 40Ma magmatism. Site IBM-2 consists of two offset drilling holes (BON-1, BON-2). BON-1 designed to first encounter forearc basalt and will reach the sheeted dykes. BON-2 will start in boninites and finish in fore arc basalts. The purpose of these drilling is sampling the full volcanic stratigraphy from gabbro to boninite. There is no seismic data around BON-1 and BON-2, therefore it is need to conduct the multi-channel seismic reflection survey. Japan Agency for Marine-Earth Science and Technology carried out multi-channel seismic reflection survey and wide-angle reflection survey using 7,800 cu.in. air gun, 5 km streamer with 444 ch hydrophones and 40 OBSs in March 2011. We obtained two seismic reflection profiles of lines KT06 and KT07 along the paleo arc around Ogasawara ridge. Line KT06 located the north side of Ogasawara ridge. Line KT07 located the trench side of Ogasawara ridge. Lines KT06 is also deployed the OBSs every 5 km interval. Thin sediments are covered with basement in both survey lines. There are some sediment filled in depression topography. The low-frequency reflection from the top of subducting Pacific plate is recognized in line KT06. The continuity of this reflection is not clear due to the complicated bathymetry. The displacement of basement in northern side of Ogasawara ridge is identified along the lineament of bathymetry in Line 06. This structure is estimated to relate the deformation in the Ogasawara Trough and lineament of paleo arc. We will discuss the relationship this lineament and deformation with regard to activity such as post volcanism.

  7. Conserved Loop Cysteines of Vitamin K Epoxide Reductase Complex Subunit 1-like 1 (VKORC1L1) Are Involved in Its Active Site Regeneration*

    PubMed Central

    Tie, Jian-Ke; Jin, Da-Yun; Stafford, Darrel W.

    2014-01-01

    Vitamin K epoxide reductase complex subunit 1 (VKORC1) reduces vitamin K epoxide in the vitamin K cycle for post-translational modification of proteins that are involved in a variety of biological functions. However, the physiological function of VKORC1-like 1 (VKORC1L1), a paralogous enzyme sharing about 50% protein identity with VKORC1, is unknown. Here we determined the structural and functional differences of these two enzymes using fluorescence protease protection (FPP) assay and an in vivo cell-based activity assay. We show that in vivo VKORC1L1 reduces vitamin K epoxide to support vitamin K-dependent carboxylation as efficiently as does VKORC1. However, FPP assays show that unlike VKORC1, VKORC1L1 is a four-transmembrane domain protein with both its termini located in the cytoplasm. Moreover, the conserved loop cysteines, which are not required for VKORC1 activity, are essential for VKORC1L1's active site regeneration. Results from domain exchanges between VKORC1L1 and VKORC1 suggest that it is VKORC1L1's overall structure that uniquely allows for active site regeneration by the conserved loop cysteines. Intermediate disulfide trapping results confirmed an intra-molecular electron transfer pathway for VKORC1L1's active site reduction. Our results allow us to propose a concerted action of the four conserved cysteines of VKORC1L1 for active site regeneration; the second loop cysteine, Cys-58, attacks the active site disulfide, forming an intermediate disulfide with Cys-139; the first loop cysteine, Cys-50, attacks the intermediate disulfide resulting in active site reduction. The different membrane topologies and reaction mechanisms between VKORC1L1 and VKORC1 suggest that these two proteins might have different physiological functions. PMID:24532791

  8. Conserved loop cysteines of vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) are involved in its active site regeneration.

    PubMed

    Tie, Jian-Ke; Jin, Da-Yun; Stafford, Darrel W

    2014-03-28

    Vitamin K epoxide reductase complex subunit 1 (VKORC1) reduces vitamin K epoxide in the vitamin K cycle for post-translational modification of proteins that are involved in a variety of biological functions. However, the physiological function of VKORC1-like 1 (VKORC1L1), a paralogous enzyme sharing about 50% protein identity with VKORC1, is unknown. Here we determined the structural and functional differences of these two enzymes using fluorescence protease protection (FPP) assay and an in vivo cell-based activity assay. We show that in vivo VKORC1L1 reduces vitamin K epoxide to support vitamin K-dependent carboxylation as efficiently as does VKORC1. However, FPP assays show that unlike VKORC1, VKORC1L1 is a four-transmembrane domain protein with both its termini located in the cytoplasm. Moreover, the conserved loop cysteines, which are not required for VKORC1 activity, are essential for VKORC1L1's active site regeneration. Results from domain exchanges between VKORC1L1 and VKORC1 suggest that it is VKORC1L1's overall structure that uniquely allows for active site regeneration by the conserved loop cysteines. Intermediate disulfide trapping results confirmed an intra-molecular electron transfer pathway for VKORC1L1's active site reduction. Our results allow us to propose a concerted action of the four conserved cysteines of VKORC1L1 for active site regeneration; the second loop cysteine, Cys-58, attacks the active site disulfide, forming an intermediate disulfide with Cys-139; the first loop cysteine, Cys-50, attacks the intermediate disulfide resulting in active site reduction. The different membrane topologies and reaction mechanisms between VKORC1L1 and VKORC1 suggest that these two proteins might have different physiological functions.

  9. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Tower Road Site in Aurora, Colorado. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Van Geet, O.; Mosey, G.

    2013-03-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Tower Road site in Aurora, Colorado, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site. This study did not assess environmental conditions at themore » site.« less

  10. Conformational motions regulate phosphoryl transfer in related protein tyrosine phosphatases

    PubMed Central

    Whittier, Sean K.; Hengge, Alvan C.; Loria, J. Patrick

    2014-01-01

    Many studies have implicated a role for conformational motions during the catalytic cycle, acting to optimize the binding pocket or facilitate product release, but a more intimate role in the chemical reaction has not been described. We address this by monitoring active-site loop motion in two protein tyrosine phosphatases (PTPs) using NMR spectroscopy. The PTPs, YopH and PTP1B, have very different catalytic rates, however we find in both that the active-site loop closes to its catalytically competent position at rates that mirror the phosphotyrosine cleavage kinetics. This loop contains the catalytic acid, suggesting that loop closure occurs concomitantly with the protonation of the leaving group tyrosine and explains the different kinetics of two otherwise chemically and mechanistically indistinguishable enzymes. PMID:23970698

  11. Develop preliminary engineering design and study the benefits of providing an access to the Indiana toll road at State Road 327 near Orland, IN.

    DOT National Transportation Integrated Search

    2016-10-05

    A new toll road exit is proposed at the intersection of I-80/90 and SR 327 in Orland, : Indiana. The new exit is needed to facilitate travel for a proposed manufacturing plant to be : established on a 500-acre site east of SR 327 and south of I-80/90...

  12. On-road bicycle facilities and bicycle crashes in Iowa, 2007-2010.

    PubMed

    Hamann, Cara; Peek-Asa, Corinne

    2013-07-01

    An average of 611 deaths and over 47,000 bicyclists are injured in traffic-related crashes in the United States each year. Efforts to increase bicycle safety are needed to reduce and prevent injuries and fatalities, especially as trends indicate that ridership is increasing rapidly. The objective of this study was to evaluate the effect of bicycle-specific roadway facilities (e.g., signage and bicycle lanes) in reducing bicycle crashes. We conducted a case site-control site study of 147 bicycle crash-sites identified from the Iowa Department of Transportation crash database from 2007 to 2010 and 147 matched non-crash sites. Control sites were randomly selected from intersections matched to case sites on neighborhood (census block group) and road classification (arterial, feeder, collector, etc.). We examined crash risk by any on-road bicycle facility present and by facility type (pavement markings--bicycle lanes and shared lane arrows, bicycle-specific signage, and the combination of markings and signage), controlling for bicycle volume, motor vehicle volume, street width, sidewalks, and traffic controls. A total of 11.6% of case sites and 15.0% of controls had an on-road bicycle facility. Case intersections had higher bicycle volume (3.52 vs. 3.34 per 30 min) and motor vehicle volume (248.77 vs. 205.76 per 30 min) than controls. Our results are suggestive that the presence of an on-road bicycle facility decreases crash risk by as much as 60% with a bicycle lane or shared lane arrow (OR=0.40, 95% CI=0.09-1.82) and 38% with bicycle-specific signage (OR=0.62, 95% CI=0.15-2.58). Investments in bicycle-specific pavement markings and signage have been shown to be beneficial to traffic flow, and our results suggest that they may also reduce the number of bicycle-motor vehicle crashes and subsequent injuries and fatalities. As a relatively low-cost traffic feature, community considerations for further implementation of these facilities are justified. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. Reverse radial artery flap for soft tissue defects of hand in pediatric age group.

    PubMed

    Cheema, Saeed Ashraf; Talaat, Nabeela

    2009-01-01

    To highlight the usefulness of reverse radial artery flap in covering various soft tissue defects of hand in paediatric age group. A total of 16 reverse radial artery flaps were utilized in a period of three years to cover various soft tissue defects of hand for paediatric age group patients. The age ranged from 5-18 years. The two common causes of soft tissue defects in this series were mechanical trauma and fireworks trauma with five cases in each group. Three of the cases were burn victims and other two presented with earth quake injuries. One patient had wound because of road traffic accident. Soft tissue defects of palm were covered with this flap in eight cases while in three cases it was wrapped around the thumb. First web space defects were covered with this flap in two cases. Two cases required coverage of amputation stump at transmetacarpal level and yet another required a big flap to cover the soft tissue defects at palm, dorsum and thumb. Donor site was covered with split skin graft in all cases but one, which was closed primarily. We had partial loss of flap in one case. Grafted donor sites healed uneventfully and were quite acceptable to the patients in due course of time. Reverse radial artery flap has a quite long arc of rotation which brings it great ease to cover the soft tissue defects of various areas of hand like palm, dorsum, first web space and thumb.

  14. 7. View of interior, EPA Farm Lab Building 1506 milk ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. View of interior, EPA Farm Lab Building 15-06 milk room, facing west - Nevada Test Site, Environmental Protection Agency Farm, Laboratory Building, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  15. 6. View of interior, EPA Farm Lab Building 1506 milking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. View of interior, EPA Farm Lab Building 15-06 milking area, facing northwest - Nevada Test Site, Environmental Protection Agency Farm, Laboratory Building, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  16. View of EPA Farm cattle shelters (Building 1506 in background), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of EPA Farm cattle shelters (Building 15-06 in background), facing southeast - Nevada Test Site, Environmental Protection Agency Farm, Shelter Unit Type, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

  17. View to the eastnortheast of the Sounder Antenna OvertheHorizon ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View to the east-northeast of the Sounder Antenna - Over-the-Horizon Backscatter Radar Network, Christmas Valley Radar Site Transmit Sector Five Sounder Antennas, On unnamed road west of Lost Forest Road, Christmas Valley, Lake County, OR

  18. View to the northeast of the antenna array OvertheHorizon ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View to the northeast of the antenna array - Over-the-Horizon Backscatter Radar Network, Christmas Valley Radar Site Transmit Sector Four Antenna Array, On unnamed road west of Lost Forest Road, Christmas Valley, Lake County, OR

  19. View to the eastnortheast of the Antenna Array OvertheHorizon ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View to the east-northeast of the Antenna Array - Over-the-Horizon Backscatter Radar Network, Christmas Valley Radar Site Transmit Sector Six Antenna Array, On unnamed road west of Lost Forest Road, Christmas Valley, Lake County, OR

  20. General view to the south of the antenna array ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view to the south of the antenna array - Over-the-Horizon Backscatter Radar Network, Christmas Valley Radar Site Transmit Sector Five Antenna Array, On unnamed road west of Lost Forest Road, Christmas Valley, Lake County, OR

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