Solid Earth and Natural Hazards (SENH) Research and Applications Program and Internation

NASA Technical Reports Server (NTRS)

2001-01-01

This is a final report for grant NAG5-8627 entitled 'Joint UNAVCO and JPL proposal to NASA for support of the Solid Earth and Natural Hazards Research and Applications Program and Internation'. This report consists of the following sections: (1) new installations (with site visits); (2) upgrades (with site visits; (3) upcoming upgrades (with site visits); and (4) data management and archive efforts during the performance period.

Biological and functional relevance of CASP predictions

PubMed Central

Liu, Tianyun; Ish‐Shalom, Shirbi; Torng, Wen; Lafita, Aleix; Bock, Christian; Mort, Matthew; Cooper, David N; Bliven, Spencer; Capitani, Guido; Mooney, Sean D.

2017-01-01

Abstract Our goal is to answer the question: compared with experimental structures, how useful are predicted models for functional annotation? We assessed the functional utility of predicted models by comparing the performances of a suite of methods for functional characterization on the predictions and the experimental structures. We identified 28 sites in 25 protein targets to perform functional assessment. These 28 sites included nine sites with known ligand binding (holo‐sites), nine sites that are expected or suggested by experimental authors for small molecule binding (apo‐sites), and Ten sites containing important motifs, loops, or key residues with important disease‐associated mutations. We evaluated the utility of the predictions by comparing their microenvironments to the experimental structures. Overall structural quality correlates with functional utility. However, the best‐ranked predictions (global) may not have the best functional quality (local). Our assessment provides an ability to discriminate between predictions with high structural quality. When assessing ligand‐binding sites, most prediction methods have higher performance on apo‐sites than holo‐sites. Some servers show consistently high performance for certain types of functional sites. Finally, many functional sites are associated with protein‐protein interaction. We also analyzed biologically relevant features from the protein assemblies of two targets where the active site spanned the protein‐protein interface. For the assembly targets, we find that the features in the models are mainly determined by the choice of template. PMID:28975675

Independent Verification Final Summary Report for the David Witherspoon, Inc. 1630 Site Knoxville, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

P.C. Weaver

2009-04-29

The primary objective of the independent verification was to determine if BJC performed the appropriate actions to meet the specified “hot spot” cleanup criteria of 500 picocuries per gram (pCi/g) uranium-238 (U-238) in surface soil. Specific tasks performed by the independent verification team (IVT) to satisfy this objective included: 1) performing radiological walkover surveys, and 2) collecting soil samples for independent analyses. The independent verification (IV) efforts were designed to evaluate radioactive contaminants (specifically U-238) in the exposed surfaces below one foot of the original site grade, given that the top one foot layer of soil on the site wasmore » removed in its entirety.« less

Classifying and profiling Social Networking Site users: a latent segmentation approach.

PubMed

Alarcón-del-Amo, María-del-Carmen; Lorenzo-Romero, Carlota; Gómez-Borja, Miguel-Ángel

2011-09-01

Social Networking Sites (SNSs) have showed an exponential growth in the last years. The first step for an efficient use of SNSs stems from an understanding of the individuals' behaviors within these sites. In this research, we have obtained a typology of SNS users through a latent segmentation approach, based on the frequency by which users perform different activities within the SNSs, sociodemographic variables, experience in SNSs, and dimensions related to their interaction patterns. Four different segments have been obtained. The "introvert" and "novel" users are the more occasional. They utilize SNSs mainly to communicate with friends, although "introverts" are more passive users. The "versatile" user performs different activities, although occasionally. Finally, the "expert-communicator" performs a greater variety of activities with a higher frequency. They tend to perform some marketing-related activities such as commenting on ads or gathering information about products and brands as well as commenting ads. The companies can take advantage of these segmentation schemes in different ways: first, by tracking and monitoring information interchange between users regarding their products and brands. Second, they should match the SNS users' profiles with their market targets to use SNSs as marketing tools. Finally, for most business, the expert users could be interesting opinion leaders and potential brand influencers.

75 FR 46914 - Certain New Pneumatic Off-the-Road Tires From the People's Republic of China: Final Results of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-04

... sites. They can also be used to perform ``rough grading'' in road construction. \\17\\ A straddle carrier... commonly used in maintenance of unpaved roads and road construction to prepare the base course on to which...-the-Road Tires From the People's Republic of China: Final Results of Changed Circumstances Review...

No Further Action Decision Document for Site 8 at Alpena Combat Readiness Training Center, Alpena, Michigan.

DTIC Science & Technology

1998-04-01

INSTALLATION RESTORATION PROGRAM No FURTHER REMEDIAL ACTION PLANNED DECISION DOCUMENT FOR SITE 8 FINAL MICHIGAN AIR NATIONAL GUARD ALPENA ...COMBAT READINESS TRAINING CENTER ALPENA , MICHIGAN April 1998 Air National Guard Andrews AFB, Maryland fr r=.~r i^:r^f>^’ m% Approved for public...Document 4. TITLE AND SUBTITLE No Further Action Decision Document for Site 8 at Alpena CRTC, Alpena , MI. 6. AUTHOR(S) N/A 7. PERFORMING

Off-site smartphone reading of CT images for patients with inconclusive diagnoses of appendicitis from on-call radiologists.

PubMed

Seong, Nak Jong; Kim, Bohyoung; Lee, Sungmin; Park, Hee Sun; Kim, Hyuk Jung; Woo, Hyunsik; Kang, Heung-Sik; Lee, Kyoung Ho

2014-07-01

The purpose of this study was to simulate a mobile consultation in patients with inconclusive diagnosis of appendicitis made by on-call radiologists, as well as to measure the diagnostic confidence and performance of the mobile consultation. Two off-site abdominal radiologists interpreted the CT images from 68 patients (including 29 patients with confirmed appendicitis) on a smart-phone for whom the preliminary CT reports by 25 in-house on-call radiologists were inconclusive. The smartphone readings were compared with the preliminary reports by on-call radiologists and with the original final reports by in-house abdominal radiologists. Heat maps, kappa statistics, Wilcoxon signed-rank tests, and ROC curves were used for data analysis. The heat maps and kappa statistics showed that the smartphone readings were more similar to the final reports than to the preliminary reports. In diagnosing or ruling out appendicitis, the smartphone readings were more confident than the preliminary reports (p ≤ 0.01) and did not significantly differ in diagnostic confidence from the final reports (p ≥ 0.19). The AUCs of the smartphone readings (0.91 and 0.92) did not differ significantly from those of the preliminary (0.85) or final (0.97) reports (p ≥ 0.09). With the given study sample, the diagnostic performance of the off-site smartphone readings did not differ significantly from that of the in-house preliminary reports. However, the smartphone readings provided higher diagnostic confidence than the preliminary reports.

Biological and functional relevance of CASP predictions.

PubMed

Liu, Tianyun; Ish-Shalom, Shirbi; Torng, Wen; Lafita, Aleix; Bock, Christian; Mort, Matthew; Cooper, David N; Bliven, Spencer; Capitani, Guido; Mooney, Sean D; Altman, Russ B

2018-03-01

Our goal is to answer the question: compared with experimental structures, how useful are predicted models for functional annotation? We assessed the functional utility of predicted models by comparing the performances of a suite of methods for functional characterization on the predictions and the experimental structures. We identified 28 sites in 25 protein targets to perform functional assessment. These 28 sites included nine sites with known ligand binding (holo-sites), nine sites that are expected or suggested by experimental authors for small molecule binding (apo-sites), and Ten sites containing important motifs, loops, or key residues with important disease-associated mutations. We evaluated the utility of the predictions by comparing their microenvironments to the experimental structures. Overall structural quality correlates with functional utility. However, the best-ranked predictions (global) may not have the best functional quality (local). Our assessment provides an ability to discriminate between predictions with high structural quality. When assessing ligand-binding sites, most prediction methods have higher performance on apo-sites than holo-sites. Some servers show consistently high performance for certain types of functional sites. Finally, many functional sites are associated with protein-protein interaction. We also analyzed biologically relevant features from the protein assemblies of two targets where the active site spanned the protein-protein interface. For the assembly targets, we find that the features in the models are mainly determined by the choice of template. © 2017 The Authors Proteins: Structure, Function and Bioinformatics Published by Wiley Periodicals, Inc.

Performance assessment for the disposal of low-level waste in the 200 West Area Burial Grounds

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wood, M.I.; Khaleel, R.; Rittmann, P.D.

1995-06-01

This document reports the findings of a performance assessment (PA) analysis for the disposal of solid low-level radioactive waste (LLW) in the 200 West Area Low-Level Waste Burial Grounds (LLBG) in the northwest corner of the 200 West Area of the Hanford Site. This PA analysis is required by US Department of Energy (DOE) Order 5820.2A (DOE 1988a) to demonstrate that a given disposal practice is in compliance with a set of performance objectives quantified in the order. These performance objectives are applicable to the disposal of DOE-generated LLW at any DOE-operated site after the finalization of the order inmore » September 1988. At the Hanford Site, DOE, Richland Operations Office (RL) has issued a site-specific supplement to DOE Order 5820.2A, DOE-RL 5820.2A (DOE 1993), which provides additiona I ce objectives that must be satisfied.« less

10 CFR 52.39 - Finality of early site permit determinations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Finality of early site permit determinations. 52.39... NUCLEAR POWER PLANTS Early Site Permits § 52.39 Finality of early site permit determinations. (a) Commission finality. (1) Notwithstanding any provision in 10 CFR 50.109, while an early site permit is in...

10 CFR 52.39 - Finality of early site permit determinations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Finality of early site permit determinations. 52.39... NUCLEAR POWER PLANTS Early Site Permits § 52.39 Finality of early site permit determinations. (a) Commission finality. (1) Notwithstanding any provision in 10 CFR 50.109, while an early site permit is in...

ARSENIC REMOVAL FROM DRINKING WATER BY PROCESS MODIFICATION TO COAGULATION/FILTRATION. USEPA DEMONSTRATION PROJECT AT LIDGERWOOD, ND. FINAL PERFORMANCE EVALUATION REPORT

EPA Science Inventory

This report documents the activities performed and the results obtained for the arsenic removal treatment technology demonstration project at the Lidgerwood, North Dakota site. The objectives of the project were to evaluate: (1) the effectiveness of process modifications to an e...

Arsenic Removal from Drinking Water by Adsorptive Media - U.S. EPA Demonstration Project at Goffstown, NH, Final Performance Evaluation Report

EPA Science Inventory

This report documents the activities performed and the results obtained from the arsenic removal treatment technology demonstration project at the Orchard Highlands Subdivision site in Goffstown, NH. The main objective of the project was to evaluate the effectiveness of AdEdge T...

ARSENIC REMOVAL FROM DRINKING WATER BY IRON REMOVAL. U.S. EPA DEMONSTRATION PROJECT AT CLIMAX, MN. FINAL PERFORMANCE EVALUATION REPORT.

EPA Science Inventory

This report documents the activities performed and the results obtained for the arsenic removal treatment technology demonstration project following one year of operation at the Climax, Minnesota, site. The objectives of the project were to evaluate: (1) the effectiveness of Kin...

Newman Unit 1 advanced solar repowering advanced conceptual design. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1982-04-01

The Newman Unit 1 solar repowering design is a water/steam central receiver concept supplying superheated steam. The work reported is to develop a refined baseline conceptual design that has potential for construction and operation by 1986, makes use of existing solar thermal technology, and provides the best economics for this application. Trade studies performed in the design effort are described, both for the conceptual design of the overall system and for the subsystem conceptual design. System-level functional requirements, design, operation, performance, cost, safety, environmental, institutional, and regulatory considerations are described. Subsystems described include the collector, receiver, fossil energy, electrical powermore » generating, and master control subsystems, site and site facilities. The conceptual design, cost, and performance of each subsystem is discussed at length. A detailed economic analysis of the repowered unit is made to realistically assess the economics of the first repowered unit using present cost data for a limited production level for solar hardware. Finally, a development plan is given, including the design, procurement, construction, checkout, startup, performance validation, and commercial operation. (LEW)« less

High Density Lidar and Orthophotography in UXO Wide Area Assessment Phase 2. Final Report Addendum for Former Camp Beale Demonstration Site, Revision 2

DTIC Science & Technology

2008-01-01

color balancing, and trimming to the delivery tiles . For the Former Camp Beale site, orthophotos were created in blocks of 2.675 square kilometers, in...3-19 3.7.12 Data Density Effects - Orthophotos ...3-27 3.7.18 Lidar and Orthophoto Positional Accuracy ........................................... 3-29 4.0 PERFORMANCE ASSESSMENT

A Systems Study to Determine the Attractiveness of Solar System Bodies and Sites for Eventual Human Exploration

NASA Technical Reports Server (NTRS)

Andringa, Jason M.; Gray, Andrew A.

2005-01-01

A pre-phase A idea-generation team at the Jet Propulsion Laboratory (JPL), has conducted a study to rank all locations in the solar system based on attractiveness for human exploration. The process used to perform the study was composed of the following primary steps: determination of criteria (including value, cost, and risk criteria) upon which to rate sites in the solar system; weighting of the criteria based upon importance to eventual human exploration; selection of sites to consider and assignment of team members to the task of advocating the benefits of particular sites; rating the sites in both the short- and longterm based on team member presentations and team discussions; compilation of a score based on criteria weights and individual ratings. Finally a comparison of the total scores of different sites was completed to determine a ranking of all the bodies and sites in the solar system. Sensitivity analysis was also performed to determine how weightings affect the rankings.

Health assessment for Colbert Landfill NPL (National Priorities List) Site, Spokane, Washington, Region 10. CERCLIS No. WAD980514541. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-07-25

The Colbert Landfill NPL site is located about fifteen miles north of Spokane, Washington. Area ground water is contaminated with several volatile organic chemicals. The medium of most concern regarding potential health effects is the ground water. Potential exposure pathways include ingestion and inhalation of volatiles from contaminated ground water and dermal exposure to contaminated ground water. The susceptible populations are remedial workers performing well water sampling on-site and populations off-site utilizing contaminated wells at levels that are of a potential health concern, for drinking, bathing, and irrigation purposes.

Reduction in surgical antibiotic prophylaxis expenditure and the rate of surgical site infection by means of a protocol that controls the use of prophylaxis.

PubMed

Gomez, Marisa I; Acosta-Gnass, Silvia I; Mosqueda-Barboza, Luisa; Basualdo, Juan A

2006-12-01

To evaluate the effectiveness of an intervention based on training and the use of a protocol with an automatic stop of antimicrobial prophylaxis to improve hospital compliance with surgical antibiotic prophylaxis guidelines. An interventional study with a before-after trial was conducted in 3 stages: a 3-year initial stage (January 1999 to December 2001), during which a descriptive-prospective survey was performed to evaluate surgical antimicrobial prophylaxis and surgical site infections; a 6-month second stage (January to June 2002), during which an educational intervention was performed regarding the routine use of a surgical antimicrobial prophylaxis request form that included an automatic stop of prophylaxis (the "automatic-stop prophylaxis form"); and a 3-year final stage (July 2002 to June 2005), during which a descriptive-prospective survey of surgical antimicrobial prophylaxis and surgical site infections was again performed. An 88-bed teaching hospital in Entre Ríos, Argentina. A total of 3,496 patients who underwent surgery were included in the first stage of the study and 3,982 were included in the final stage. Comparison of the first stage of the study with the final stage revealed that antimicrobial prophylaxis was given at the appropriate time to 55% and 88% of patients, respectively (relative risk [RR], 0.27 [95% confidence interval {CI}, 0.25-0.30]; P<.01); the antimicrobial regimen was adequate in 74% and 87% of patients, respectively (RR, 0.50 [95% CI, 0.45-0.55]; P<.01); duration of the prophylaxis was adequate in 44% and 55% of patients, respectively (RR, 0.80 [95% CI, 0.77-0.84]; P<.01); and the surgical site infection rates were 3.2% and 1.9%, respectively (RR, 0.59 [95% CI, 0.44-0.79]; P<.01). Antimicrobial expenditure was 10,678.66 US$ per 1,000 patient-days during the first stage and 7,686.05 US$ per 1,000 patient-days during the final stage (RR, 0.87 [95% CI, 0.86-0.89]; P<.01). The intervention based on training and application of a protocol with an automatic stop of prophylaxis favored compliance with the hospital's current surgical antibiotic prophylaxis guidelines before the intervention, achieving significant reductions of surgical site infection rates and substantial savings for the healthcare system.

'Advancement of KHPS to DOE TRL 7/8' Project - Final Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adonizio, Mary Ann; Corren, Dean; Smith, Ron

Final Report describing activities performed under the 'Advancement of the KHPS to DOE TRL 7/8' project, including the development of critical component test protocols, testing and analysis of the Gen5 KHPS main shaft seal, and continuing compliance work on approved operational environmental monitoring plans in anticipation of KHPS turbine installation at Verdant Power's Roosevelt Island Tidal Energy (RITE) Project site in New York, NY.

Final system instrumentation design package for Decade 80 solar house

NASA Technical Reports Server (NTRS)

1978-01-01

The final configuration of the Decade 80 solar house to monitor and collect system performance data is presented. A review demonstrated by actual operation that the system and the data acquisition subsystem operated satisfactorily and installation of instrumentation was in accordance with the design. This design package is made up of (1) site and system description, (2) operating and control modes, and (3) instrumentation program (including sensor schematic).

Arsenic Removal from Drinking Water by Iron Removal U.S. EPA Demonstration Project at Sabin, MN Final Performance Evaluation Report

EPA Science Inventory

This report documents the activities performed and the results obtained from January 30, 2006 to April 29, 2007 at the U.S. Environmental Protection Agency (EPA) Arsenic Removal Technology Demonstration site in Sabin, MN. The main objective of the project was to evaluate the eff...

Camp Verde Adult Reading Program. Final Performance Report.

ERIC Educational Resources Information Center

Maynard, David A.

This document begins with a four-page performance report describing how the Camp Verde Adult Reading Program site was relocated to the Community Center Complex, and the Town Council contracted directly with the Friends of the Camp Verde Library to provide for the requirements of the program. The U.S. Department of Education grant allowed the…

SPSP Phase III Recruiting, Selecting, and Developing Secure Power Systems Professionals. Individual and Team Performance Guidelines

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Neil, Lori Ross; Conway, T. J.; Tobey, D. H.

The Secure Power Systems Professional Phase III final report was released last year which an appendix of Individual and Team Performance Guidelines. This new report is that appendix broken out as a standalone document to assist utilities in recruiting and developing Secure Power Systems Professionals at their site.

Preliminary access routes and cost study analyses for seven potentially acceptable salt sites: Final report, October 1984

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1987-02-01

This report analyzes highway and railroad access to seven potentially acceptable salt repository sites: Richton Dome and Cypress Creek Dome in Mississippi, Vacherie Dome in Louisiana, Swisher County and Deaf Smith County in Texas, and Davis Canyon and Lavender Canyon in utah. The objectives of the study were to investigate the routing of reasonable access corridors to the sites, describe major characteristics of each route, and estimate the costs for constructing or upgrading highways and railroads. The routes used in the analysis are not necessarily recommended or preferred over other routes, nor do they represent an implied final selection. Detailedmore » engineering studies must be performed for the Davis Canyon and Lavender Canyon highway access before the analyzed routes can be considered to be viable. 20 refs., 7 figs., 3 tabs.« less

Supporting evaluation for the proposed plan for final remedial action for the groundwater operable unit at the chemical plant area of the Weldon Spring Site, Weldon Spring, Missouri.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2003-08-06

This report presents the technical information developed since the interim record of decision (IROD) was issued in September 2000 (U.S. Department of Energy [DOE] 2000). The information was incorporated into the evaluation that was performed in selecting the preferred alternative for the Chemical Plant groundwater operable unit (GWOU) of the Weldon Spring site. The contaminants of concern (COCs) in groundwater and springs are trichloroethylene (TCE), nitrate, uranium, and nitroaromatic compounds. The preferred alternative of monitored natural attenuation (MNA) coupled with institutional controls (ICs) and contingency activities is described in the ''Proposed Plan (PP) for Final Remedial Action for the Groundwatermore » Operable Unit at the Chemical Plant Area of the Weldon Spring Site, Weldon Spring, Missouri'' (DOE 2003b).« less

Simulating Radionuclide Migrations of Low-level Wastes in Nearshore Environment

NASA Astrophysics Data System (ADS)

Lu, C. C.; Li, M. H.; Chen, J. S.; Yeh, G. T.

2016-12-01

Tunnel disposal into nearshore mountains was tentatively selected as one of final disposal sites for low-level wastes in Taiwan. Safety assessment on radionuclide migrations in far-filed may involve geosphere processes under coastal environments and into nearshore ocean. In this study the 3-D HYDROFEOCHE5.6 numerical model was used to perform simulations of groundwater flow and radionuclide transport with decay chains. Domain of interest on the surface includes nearby watersheds delineated by digital elevation models and nearshore seabed. As deep as 800 m below the surface and 400 m below sea bed were considered for simulations. The disposal site was located at 200m below the surface. Release rates of radionuclides from near-field was estimated by analytical solutions of radionuclide diffusion with decay out of engineered barriers. Far-field safety assessments were performed starting from the release of radionuclides out of engineered barriers to a time scale of 10,000 years. Sensitivity analyses of geosphere and transport parameters were performed to improve our understanding of safety on final disposal of low-level waste in nearshore environments.

Community Structure and Standing Stock of Epibenthic Zooplankton at Five Sites in Grays Harbor, Washington

DTIC Science & Technology

1981-09-01

4 GRAYS HARBOR AND CHEHALIS RIVER IMPROVEMENTS TO NAVIGATION ENVIRONMENTAL STUDIES COMMUNITY STRUCTURE AND STANDING © STOCK OF EPIBENTHIC... FISHERIES RESEARCH INSTITUTE %r UNIVERSITY OF WASHINGTON B of Engineers SEPTEMBER 1981 Seattle District(DISTRIBUTION STATEM EN T. -A-8-1 2 7 Approved...PERIOD COVERED Community Structure and Standing Stock of Final May 7. 1981 Epibenthic Zooplankton at Five Sites in 6. PERFORMING ORG. REPORT NUMBER

United States Air Force 611th Air Support Group/Civil Engineering Squadron Elmendorf AFB, Alaska. Remedial investigation and feasibility study. Barter Island Radar Installation, Alaska. Volume 1 (includes appendices a through c). Revision 1. Final report, January 1995-January 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karmi, S.; Madden, J.; Borsetti, R.

1996-01-05

This report presents the findings of Remedial Investigations and Feasibility Studies at sites located at the Barter Island radar installation in northern Alaska. The sites were characterized based on sampling and analyses conducted during Remedial Investigation activities performed during August and September 1993.

From the utilization point of view, the two approaches seem to United States Air Force 611th Air Support Group/Civil Engineering Squadron, Elmendorf AFB, Alaska. Remedial investigation and feasibility study Point Barrow Radar Installation, Alaska. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karmi, S.

1996-02-19

This report presents the findings of Remedial Investigations and Feasibility Studies at sites located at the Point Barrow radar installation in northern Alaska. The sites were characterized based on sampling and analyses conducted during Remedial Investigation activities performed during August and September 1993.

Evaluation and implementation of BMPs for NCDOT's highway and industrial facilities : final report, May 2006.

DOT National Transportation Integrated Search

2006-05-01

This research has provided NCDOT with (1) scientific observations to validate the pollutant removal : performance of selected structural BMPs, (2) a database management option for BMP monitoring and : non-monitoring sites, (3) pollution prevention pl...

Future Performance Trend Indicators: A Current Value Approach to Human Resources Accounting. Report I. Internal Consistencies and Relationships to Performance By Site. Final Report.

ERIC Educational Resources Information Center

Pecorella, Patricia A.; Bowers, David G.

Analyses preparatory to construction of a suitable file for generating a system of future performance trend indicators are described. Such a system falls into the category of a current value approach to human resources accounting. It requires that there be a substantial body of data which: (1) uses the work group or unit, not the individual, as…

Analytical study of nano-scale logical operations

NASA Astrophysics Data System (ADS)

Patra, Moumita; Maiti, Santanu K.

2018-07-01

A complete analytical prescription is given to perform three basic (OR, AND, NOT) and two universal (NAND, NOR) logic gates at nano-scale level using simple tailor made geometries. Two different geometries, ring-like and chain-like, are taken into account where in each case the bridging conductor is coupled to a local atomic site through a dangling bond whose site energy can be controlled by means of external gate electrode. The main idea is that when injecting electron energy matches with site energy of local atomic site transmission probability drops exactly to zero, whereas the junction exhibits finite transmission for other energies. Utilizing this prescription we perform logical operations, and, we strongly believe that the proposed results can be verified in laboratory. Finally, we numerically compute two-terminal transmission probability considering general models and the numerical results match exactly well with our analytical findings.

40 CFR 228.15 - Dumping sites designated on a final basis.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Dumping sites designated on a final basis. 228.15 Section 228.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE MANAGEMENT OF DISPOSAL SITES FOR OCEAN DUMPING § 228.15 Dumping sites designated on a final basis. (a)(1) The sites...

40 CFR 228.15 - Dumping sites designated on a final basis.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Dumping sites designated on a final basis. 228.15 Section 228.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE MANAGEMENT OF DISPOSAL SITES FOR OCEAN DUMPING § 228.15 Dumping sites designated on a final basis. (a)(1) The sites...

40 CFR 228.15 - Dumping sites designated on a final basis.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Dumping sites designated on a final basis. 228.15 Section 228.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE MANAGEMENT OF DISPOSAL SITES FOR OCEAN DUMPING § 228.15 Dumping sites designated on a final basis. (a)(1) The sites...

40 CFR 228.15 - Dumping sites designated on a final basis.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Dumping sites designated on a final basis. 228.15 Section 228.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE MANAGEMENT OF DISPOSAL SITES FOR OCEAN DUMPING § 228.15 Dumping sites designated on a final basis. (a)(1) The sites...

Field Performance Of Three Compacted Clay Landfill Covers

EPA Science Inventory

A study was conducted at sites in subtropical Georgia, seasonal and humid Iowa, and arid southeastern California to evaluate the field hydrology of compacted clay covers for final closure of landfills. Water balance of the covers was monitored with large (10 by 20 m ), instrumen...

Installation restoration program. Site investigation report. Volume 1: Section 1 through 6. 155th Air Refueling Group, Nebraska Air National Guard, Lincoln, Nebraska. Revision 04. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-04-01

Site Investigation Report, Volume 1: Sections 1 through 6, Appendix A. A Site Investigation was performed at the 155th Air Refueling Group at Lincoln, NE to evaluate six areas of suspected contamination identified during a Preliminary Assessment. The sites that this investigation were conducted at are: Site 1- Fuel Farm, POL Storage Area, Site 2 - West End of Old Oak Creek, Site 3 Former Tank Cleaning/Hazardous Waste Storage Area, Site 4 - Access Road, Dust Control Area, , Site 5 - Army National Guard Oil Storage Area, and Site 6 - Hydraulic Pressure Check Unit Storage Area. The reportmore » recommended no further action for Sites 3 through 6 due to low levels or no contamination being found. The report recommended that the portion of Site 2 that is located downstream of Site 1 should be included in Site 1.« less

Discovering body site and severity modifiers in clinical texts

PubMed Central

Dligach, Dmitriy; Bethard, Steven; Becker, Lee; Miller, Timothy; Savova, Guergana K

2014-01-01

Objective To research computational methods for discovering body site and severity modifiers in clinical texts. Methods We cast the task of discovering body site and severity modifiers as a relation extraction problem in the context of a supervised machine learning framework. We utilize rich linguistic features to represent the pairs of relation arguments and delegate the decision about the nature of the relationship between them to a support vector machine model. We evaluate our models using two corpora that annotate body site and severity modifiers. We also compare the model performance to a number of rule-based baselines. We conduct cross-domain portability experiments. In addition, we carry out feature ablation experiments to determine the contribution of various feature groups. Finally, we perform error analysis and report the sources of errors. Results The performance of our method for discovering body site modifiers achieves F1 of 0.740–0.908 and our method for discovering severity modifiers achieves F1 of 0.905–0.929. Discussion Results indicate that both methods perform well on both in-domain and out-domain data, approaching the performance of human annotators. The most salient features are token and named entity features, although syntactic dependency features also contribute to the overall performance. The dominant sources of errors are infrequent patterns in the data and inability of the system to discern deeper semantic structures. Conclusions We investigated computational methods for discovering body site and severity modifiers in clinical texts. Our best system is released open source as part of the clinical Text Analysis and Knowledge Extraction System (cTAKES). PMID:24091648

Discovering body site and severity modifiers in clinical texts.

PubMed

Dligach, Dmitriy; Bethard, Steven; Becker, Lee; Miller, Timothy; Savova, Guergana K

2014-01-01

To research computational methods for discovering body site and severity modifiers in clinical texts. We cast the task of discovering body site and severity modifiers as a relation extraction problem in the context of a supervised machine learning framework. We utilize rich linguistic features to represent the pairs of relation arguments and delegate the decision about the nature of the relationship between them to a support vector machine model. We evaluate our models using two corpora that annotate body site and severity modifiers. We also compare the model performance to a number of rule-based baselines. We conduct cross-domain portability experiments. In addition, we carry out feature ablation experiments to determine the contribution of various feature groups. Finally, we perform error analysis and report the sources of errors. The performance of our method for discovering body site modifiers achieves F1 of 0.740-0.908 and our method for discovering severity modifiers achieves F1 of 0.905-0.929. Results indicate that both methods perform well on both in-domain and out-domain data, approaching the performance of human annotators. The most salient features are token and named entity features, although syntactic dependency features also contribute to the overall performance. The dominant sources of errors are infrequent patterns in the data and inability of the system to discern deeper semantic structures. We investigated computational methods for discovering body site and severity modifiers in clinical texts. Our best system is released open source as part of the clinical Text Analysis and Knowledge Extraction System (cTAKES).

Geological considerations in hazardouswaste disposal

NASA Astrophysics Data System (ADS)

Cartwright, K.; Gilkeson, R. H.; Johnson, T. M.

1981-12-01

Present regulations assume that long-term isolation of hazardous wastes — including toxic chemical, biological, radioactive, flammable and explosive wastes — may be effected by disposal in landfills that have liners of very low hydraulic conductivity. In reality, total isolation of wastes in humid areas is not possible; some migration of leachate from wastes buried in the gound will always occur. Regulations should provide performance standards applicable on a site-by-site basis rather than rigid criteria for site selection and design. The performance standards should take into account several factors: (1) the categories, segregation, degradation and toxicity of the wastes; (2) the site hydrogeology, which governs the direction and rate of contaminant transport; (3) the attenuation of contaminants by geochemical interactions with geologic materials; and (4) the release rate of unattenuated pollutants to surface or groundwater. An adequate monitoring system is essential. The system should both test the extent to which the operation of the site meets performance standards and provide sufficient warning of pollution problems to allow implementation of remedial measures. In recent years there has been a trend away from numerous, small disposal sites toward fewer and larger sites. The size of a disposal site should be based on the attenuation capacity of the geologic material, which has a finite, though generally not well-defined, limit. For slowly degradable wastes, engineered sites with leachate-collection systems appear to be only a temporary solution since the leachate collected will also require final disposal.

Geological considerations in hazardouswaste disposal

USGS Publications Warehouse

Cartwright, K.; Gilkeson, R.H.; Johnson, T.M.

1981-01-01

Present regulations assume that long-term isolation of hazardous wastes - including toxic chemical, biological, radioactive, flammable and explosive wastes - may be effected by disposal in landfills that have liners of very low hydraulic conductivity. In reality, total isolation of wastes in humid areas is not possible; some migration of leachate from wastes buried in the gound will always occur. Regulations should provide performance standards applicable on a site-by-site basis rather than rigid criteria for site selection and design. The performance standards should take into account several factors: (1) the categories, segregation, degradation and toxicity of the wastes; (2) the site hydrogeology, which governs the direction and rate of contaminant transport; (3) the attenuation of contaminants by geochemical interactions with geologic materials; and (4) the release rate of unattenuated pollutants to surface or groundwater. An adequate monitoring system is essential. The system should both test the extent to which the operation of the site meets performance standards and provide sufficient warning of pollution problems to allow implementation of remedial measures. In recent years there has been a trend away from numerous, small disposal sites toward fewer and larger sites. The size of a disposal site should be based on the attenuation capacity of the geologic material, which has a finite, though generally not well-defined, limit. For slowly degradable wastes, engineered sites with leachate-collection systems appear to be only a temporary solution since the leachate collected will also require final disposal. ?? 1981.

Evaluation of performance and cost-effectiveness of thin pavement surface treatments : final report.

DOT National Transportation Integrated Search

1993-05-01

This study describes the findings from the study of 87 closely monitored sites in the State of Oregon which were treated with different types of thin surface materials. All of these surface treatments had a total thickness of two inches or less, and ...

Improving adaptive/responsive signal control performance : implications of non-invasive detection and legacy timing practices : final report.

DOT National Transportation Integrated Search

2017-02-01

This project collected and analyzed event based vehicle detection data from multiple technologies at four different sites across Oregon to provide guidance for deployment of non-invasive detection for use in adaptive control, as well as develop a tru...

WINS: Workplace Improvement of Necessary Skills. Final Report.

ERIC Educational Resources Information Center

Dwyer, Ann

The Workplace Improvement of Necessary Skills (WINS) project was initiated by a statewide coalition of Washington businesses and educational institutions to prepare workers in a number of high-performance workplaces to participate fully in their work environments. Together, the project's 11 sites served 872 participants. All project instructors…

13 CFR 120.451 - How does a Lender become a PLP Lender?

Code of Federal Regulations, 2010 CFR

2010-01-01

... for final decision. (b) In making its decision, SBA considers whether the Lender: (1) Has the required.... The Lender's Risk Rating, among other factors, will be considered in determining satisfactory SBA performance. Other factors may include, but are not limited to, on-site review/examination assessments...

13 CFR 120.812 - Probationary period for newly certified CDCs.

Code of Federal Regulations, 2010 CFR

2010-01-01

... its recommendation to the D/FA, who will make the final decision. SBA will determine permanent CDC... discretion. The CDC's Risk Rating, among other factors, will be considered in determining satisfactory SBA performance. Other factors may include, but are not limited to, on-site review/examination assessments...

Polycystic ovary syndrome: double click and right check. What do patients learn from the Internet about PCOS?

PubMed

Mousiolis, Athanasios; Michala, Lina; Antsaklis, Aris

2012-07-01

To identify the websites most visited by patients regarding polycystic ovary syndrome (PCOS), and to evaluate the quality of information provided by these websites. We sought data regarding the popularity of sites providing information about PCOS regardless of the way the visitors reached the site. We then scrutinized the top sites for predefined quality check points to evaluate the quality of information provided, including Health on Net Foundation (HON) accreditation. Finally, we searched for the expansion of these sites in social networks (Facebook and Twitter). Of the top 15 sites, 8 were HONcode certified. The mean performance of content presence for all sites was 7.33 (min=4, max=10, SD=1.633). There was a moderate correlation of higher performance score with HON accreditation (R: 0.535, p<0.05). Several sites have expanded in social media. None of the high-score sites has a page dedicated to PCOS. There exists a lack of HON accreditation in many sites and a wide variability in the quality of the information provided. In some cases, key elements of content, necessary for complete appreciation of PCOS, are missing. Official and high authority healthcare organisms should introduce themselves in the social media world. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Final Report Feasibility Study for the California Wave Energy Test Center (CalWavesm)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blakeslee, Samuel Norman; Toman, William I.; Williams, Richard B.

The California Wave Energy Test Center (CalWave) Feasibility Study project was funded over multiple phases by the Department of Energy to perform an interdisciplinary feasibility assessment to analyze the engineering, permitting, and stakeholder requirements to establish an open water, fully energetic, grid connected, wave energy test center off the coast of California for the purposes of advancing U.S. wave energy research, development, and testing capabilities. Work under this grant included wave energy resource characterization, grid impact and interconnection requirements, port infrastructure and maritime industry capability/suitability to accommodate the industry at research, demonstration and commercial scale, and macro and micro sitingmore » considerations. CalWave Phase I performed a macro-siting and down-selection process focusing on two potential test sites in California: Humboldt Bay and Vandenberg Air Force Base. This work resulted in the Vandenberg Air Force Base site being chosen as the most favorable site based on a peer reviewed criteria matrix. CalWave Phase II focused on four siting location alternatives along the Vandenberg Air Force Base coastline and culminated with a final siting down-selection. Key outcomes from this work include completion of preliminary engineering and systems integration work, a robust turnkey cost estimate, shoreside and subsea hazards assessment, storm wave analysis, lessons learned reports from several maritime disciplines, test center benchmarking as compared to existing international test sites, analysis of existing applicable environmental literature, the completion of a preliminary regulatory, permitting and licensing roadmap, robust interaction and engagement with state and federal regulatory agency personnel and local stakeholders, and the population of a Draft Federal Energy Regulatory Commission (FERC) Preliminary Application Document (PAD). Analysis of existing offshore oil and gas infrastructure was also performed to assess the potential value and re-use scenarios of offshore platform infrastructure and associated subsea power cables and shoreside substations. The CalWave project team was well balanced and was comprised of experts from industry, academia, state and federal regulatory agencies. The result of the CalWave feasibility study finds that the CalWave Test Center has the potential to provide the most viable path to commercialization for wave energy in the United States.« less

Accurate in silico prediction of species-specific methylation sites based on information gain feature optimization.

PubMed

Wen, Ping-Ping; Shi, Shao-Ping; Xu, Hao-Dong; Wang, Li-Na; Qiu, Jian-Ding

2016-10-15

As one of the most important reversible types of post-translational modification, protein methylation catalyzed by methyltransferases carries many pivotal biological functions as well as many essential biological processes. Identification of methylation sites is prerequisite for decoding methylation regulatory networks in living cells and understanding their physiological roles. Experimental methods are limitations of labor-intensive and time-consuming. While in silicon approaches are cost-effective and high-throughput manner to predict potential methylation sites, but those previous predictors only have a mixed model and their prediction performances are not fully satisfactory now. Recently, with increasing availability of quantitative methylation datasets in diverse species (especially in eukaryotes), there is a growing need to develop a species-specific predictor. Here, we designed a tool named PSSMe based on information gain (IG) feature optimization method for species-specific methylation site prediction. The IG method was adopted to analyze the importance and contribution of each feature, then select the valuable dimension feature vectors to reconstitute a new orderly feature, which was applied to build the finally prediction model. Finally, our method improves prediction performance of accuracy about 15% comparing with single features. Furthermore, our species-specific model significantly improves the predictive performance compare with other general methylation prediction tools. Hence, our prediction results serve as useful resources to elucidate the mechanism of arginine or lysine methylation and facilitate hypothesis-driven experimental design and validation. The tool online service is implemented by C# language and freely available at http://bioinfo.ncu.edu.cn/PSSMe.aspx CONTACT: jdqiu@ncu.edu.cnSupplementary information: Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

An Assessment of Long-Term Compliance with Performance Standards in Compensatory Mitigation Wetlands.

PubMed

Van den Bosch, Kyle; Matthews, Jeffrey W

2017-04-01

Under the US Clean Water Act, wetland restoration is used to compensate for adverse impacts to wetlands. Following construction, compensation wetlands are monitored for approximately 5 years to determine if they comply with project-specific performance standards. Once a compensation site complies with performance standards, it is assumed that the site will continue to meet standards indefinitely. However, there have been few assessments of long-term compliance. We surveyed, in 2012, 30 compensation sites 8-20 years after restoration to determine whether projects continued to meet performance standards. Additionally, we compared floristic quality of compensation sites to the quality of adjacent natural wetlands to determine whether wetland condition in compensation sites could be predicted based on the condition of nearby wetlands. Compensation sites met, on average, 65% of standards during the final year of monitoring and 53% of standards in 2012, a significant decrease in compliance. Although forested wetlands often failed to meet standards for planted tree survival, the temporal decrease in compliance was driven by increasing dominance by invasive plants in emergent wetlands. The presumption of continued compliance with performance standards after a 5-year monitoring period was not supported. Wetlands restored near better quality natural wetlands achieved and maintained greater floristic quality, suggesting that landscape context was an important determinant of long-term restoration outcomes. Based on our findings, we recommend that compensation wetlands should be monitored for longer time periods, and we suggest that nearby or adjacent natural wetlands provide good examples of reasonably achievable restoration outcomes in a particular landscape.

New York State Police remote communications site small wind energy conversion system. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1985-03-01

This report concludes a year-long demonstration and study of the use of a North Wind Model HR2 wind energy conversion system to supply the power for a remote New York State Police microwave repeater site at Mt. Morris in the Adirondack Mountains. Data were collected on a multi-channel digital strip chart recorder which provided a printout of the real-time relation between windspeed, power output, battery capacity and voltage, and contribution from backup power. These data proved that the site could be run on wind power alone and predictions can now be made on the performance of an HR2 or similarmore » wind system at other sites. 5 figs., 1 tab.« less

Prediction of drilling site-specific interaction of industrial acoustic stimuli and endangered whales: Beaufort Sea (1985). Final report, July 1985-March 1986

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miles, P.R.; Malme, C.I.; Shepard, G.W.

1986-10-01

Research was performed during the first year (1985) of the two-year project investigating potential responsiveness of bowhead and gray whales to underwater sounds associated with offshore oil-drilling sites in the Alaskan Beaufort Sea. The underwater acoustic environment and sound propagation characteristics of five offshore sites were determined. Estimates of industrial noise levels versus distance from those sites are provided. LGL Ltd. (bowhead) and BBN (gray whale) jointly present zones of responsiveness of these whales to typical underwater sounds (drillship, dredge, tugs, drilling at gravel island). An annotated bibliography regarding the potential effects of offshore industrial noise on bowhead whales inmore » the Beaufort Sea is included.« less

Harmonization of multi-site diffusion tensor imaging data.

PubMed

Fortin, Jean-Philippe; Parker, Drew; Tunç, Birkan; Watanabe, Takanori; Elliott, Mark A; Ruparel, Kosha; Roalf, David R; Satterthwaite, Theodore D; Gur, Ruben C; Gur, Raquel E; Schultz, Robert T; Verma, Ragini; Shinohara, Russell T

2017-11-01

Diffusion tensor imaging (DTI) is a well-established magnetic resonance imaging (MRI) technique used for studying microstructural changes in the white matter. As with many other imaging modalities, DTI images suffer from technical between-scanner variation that hinders comparisons of images across imaging sites, scanners and over time. Using fractional anisotropy (FA) and mean diffusivity (MD) maps of 205 healthy participants acquired on two different scanners, we show that the DTI measurements are highly site-specific, highlighting the need of correcting for site effects before performing downstream statistical analyses. We first show evidence that combining DTI data from multiple sites, without harmonization, may be counter-productive and negatively impacts the inference. Then, we propose and compare several harmonization approaches for DTI data, and show that ComBat, a popular batch-effect correction tool used in genomics, performs best at modeling and removing the unwanted inter-site variability in FA and MD maps. Using age as a biological phenotype of interest, we show that ComBat both preserves biological variability and removes the unwanted variation introduced by site. Finally, we assess the different harmonization methods in the presence of different levels of confounding between site and age, in addition to test robustness to small sample size studies. Copyright © 2017 Elsevier Inc. All rights reserved.

US DOE-EM On-Site Disposal Cell Working Group - Fostering Communication On Performance Assessment Challenges

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seitz, Roger R.; Suttora, Linda C.; Phifer, Mark

On-site disposal cells are in use and being considered at several U.S. Department of Energy (USDOE) sites as the final disposition for large amounts of waste associated with cleanup of contaminated areas and facilities. These facilities are typically developed with regulatory oversight from States and/or the US Environmental Protection Agency (USEPA) in addition to USDOE. The facilities are developed to meet design standards for disposal of hazardous waste as well as the USDOE performance based standards for disposal of radioactive waste. The involvement of multiple and different regulators for facilities across separate sites has resulted in some differences in expectationsmore » for performance assessments and risk assessments (PA/RA) that are developed for the disposal facilities. The USDOE-EM Office of Site Restoration formed a working group to foster improved communication and sharing of information for personnel associated with these Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) disposal cells and work towards more consistent assumptions, as appropriate, for technical and policy considerations related to performance and risk assessments in support of a Record of Decision and Disposal Authorization Statement. The working group holds teleconferences, as needed, focusing on specific topics of interest. The topics addressed to date include an assessment of the assumptions used for performance assessments and risk assessments (PA/RAs) for on-site disposal cells, requirements and assumptions related to assessment of inadvertent intrusion, DOE Manual 435.1-1 requirements, and approaches for consideration of the long-term performance of liners and covers in the context of PAs. The working group has improved communication among the staff and oversight personnel responsible for onsite disposal cells and has provided a forum to identify and resolve common concerns.« less

Site-conditions map for Portugal based on VS measurements: methodology and final model

NASA Astrophysics Data System (ADS)

Vilanova, Susana; Narciso, João; Carvalho, João; Lopes, Isabel; Quinta Ferreira, Mario; Moura, Rui; Borges, José; Nemser, Eliza; Pinto, carlos

2017-04-01

In this paper we present a statistically significant site-condition model for Portugal based on shear-wave velocity (VS) data and surface geology. We also evaluate the performance of commonly used Vs30 proxies based on exogenous data and analyze the implications of using those proxies for calculating site amplification in seismic hazard assessment. The dataset contains 161 Vs profiles acquired in Portugal in the context of research projects, technical reports, academic thesis and academic papers. The methodologies involved in characterizing the Vs structure at the sites in the database include seismic refraction, multichannel analysis of seismic waves and refraction microtremor. Invasive measurements were performed in selected locations in order to compare the Vs profiles obtained from both invasive and non-invasive techniques. In general there was good agreement in the subsurface structure of Vs30 obtained from the different methodologies. The database flat-file includes information on Vs30, surface geology at 1:50.000 and 1:500.000 scales, elevation and topographic slope and based on SRTM30 topographic dataset. The procedure used to develop the site-conditions map is based on a three-step process that includes defining a preliminary set of geological units based on the literature, performing statistical tests to assess whether or not the differences in the distributions of Vs30 are statistically significant, and merging of the geological units accordingly. The dataset was, to some extent, affected by clustering and/or preferential sampling and therefore a declustering algorithm was applied. The final model includes three geological units: 1) Igneous, metamorphic and old (Paleogene and Mesozoic) sedimentary rocks; 2) Neogene and Pleistocene formations, and 3) Holocene formations. The evaluation of proxies indicates that although geological analogues and topographic slope are in general unbiased, the latter shows significant bias for particular geological units and subsequently for some geographical regions.

The Potential of Environmental Sensors for Improving the Mobility Performance of Mainstream Blind Students. Final Report.

ERIC Educational Resources Information Center

Weisgerber, Robert A.; deHaas, Carla

The report describes an effort to develop and test instructional materials, techniques and procedures - ESSETS (environmental sensing, selection, evaluation and training system) - for teaching functionally blind young adults to use electronic travel aids (ETAs). Considered are development of training guidelines, field site selection and instructor…

Distribution of end bearing, tip shear and rotation on drilled shafts with combined loading in Florida limestone : final report, May 2008.

DOT National Transportation Integrated Search

2008-05-01

The study investigated the behavior of large diameter drilled shafts embedded short distances in Florida Limestone (i.e. L/D=1 &3). The work was performed via laboratory (centrifuge) tests and at two field sites (17th Street and Fuller Warren Bridges...

Field Performance of Three-Phase Amorphous Metal Core Distribution Transformers at Pearl Harbor, Hawaii

DTIC Science & Technology

1990-08-01

transformer core, such as loose or fractured core laminations . A sound level meter with an A- weighting frequency network was used for the...loaded on flatbed trucks as shown in Figure 2 and permanently installed at various sites throughout the Pearl Harbor complex. Figure 3 shows the final

Rapid on-site evaluation of fine needle aspiration specimens by cytology scientists: a review of 3032 specimens.

PubMed

Shield, P W; Cosier, J; Ellerby, G; Gartrell, M; Papadimos, D

2014-10-01

To determine: (1) the accuracy of cytology scientists at assessing specimen adequacy by rapid on-site evaluation (ROSE) at fine needle aspiration (FNA) cytology collections; and (2) whether thyroid FNA with ROSE has lower inadequacy rates than non-attended FNAs. The ROSE of adequacy for 3032 specimens from 17 anatomical sites collected over a 20-month period was compared with the final report assessment of adequacy. ROSE was performed by 19 cytology scientists. The report profile for 1545 thyroid nodules with ROSE was compared with that for 1536 consecutive non-ROSE thyroid FNAs reported by the same cytopathologists during the study period. ROSE was adequate in 75% (2276/3032), inadequate in 12% (366/3032) and in 13% (390/3032) no opinion was rendered. Of the 2276 cases assessed as adequate by ROSE, 2268 (99.6%) were finally reported as adequate for assessment; eight specimens had adequacy downgraded on the final report. Fifty eight per cent of cases with a ROSE assessment of inadequate were reported as adequate (212/366), whereas 93% (363/390) with no opinion rendered were reported as adequate. The overall final report adequacy rate for the 3032 specimens was 94% (2843/3032). Confirmation of a ROSE of adequacy at reporting was uniformly high amongst the 19 scientists, ranging from 98% to 100%. The inadequacy rate for thyroid FNAs with ROSE (6%) was significantly (P < 0.0001) lower than for non-ROSE thyroid FNAs (17%). A significantly (P = 0.02) higher proportion of adequate ROSE thyroid specimens was reported with abnormalities, compared with non-ROSE thyroid collections. Cytology scientists are highly accurate at determining specimen adequacy at ROSE for a wide range of body sites. ROSE of thyroid FNAs can significantly reduce inadequate reports. © 2014 John Wiley & Sons Ltd.

SITE project. Phase 1: Continuous data bit-error-rate testing

NASA Technical Reports Server (NTRS)

Fujikawa, Gene; Kerczewski, Robert J.

1992-01-01

The Systems Integration, Test, and Evaluation (SITE) Project at NASA LeRC encompasses a number of research and technology areas of satellite communications systems. Phase 1 of this project established a complete satellite link simulator system. The evaluation of proof-of-concept microwave devices, radiofrequency (RF) and bit-error-rate (BER) testing of hardware, testing of remote airlinks, and other tests were performed as part of this first testing phase. This final report covers the test results produced in phase 1 of the SITE Project. The data presented include 20-GHz high-power-amplifier testing, 30-GHz low-noise-receiver testing, amplitude equalization, transponder baseline testing, switch matrix tests, and continuous-wave and modulated interference tests. The report also presents the methods used to measure the RF and BER performance of the complete system. Correlations of the RF and BER data are summarized to note the effects of the RF responses on the BER.

The SKI repository performance assessment project Site-94

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andersson, J.; Dverstorp, B.; Sjoeblom, R.

1995-12-01

SITE-94 is a research project conducted as a performance assessment of a hypothetical repository for spent nuclear fuel, but with real pre-excavation data from a real site. The geosphere, the engineered barriers and the processes for radionuclide release and transport comprise an integrated interdependent system, which is described by an influence diagram (PID) that reflects how different Features, Events or Processes (FEPs) inside the system interact. Site evaluation is used to determine information of transport paths in the geosphere and to deliver information on geosphere interaction with the engineered barriers. A three-dimensional geological structure model of the site as wellmore » as alternative conceptual models consistent with the existing hydrological field data, have been analyzed. Groundwater chemistry is evaluated and a model, fairly consistent with the flow model, for the origin of the different waters has been developed. The geological structure model is also used for analyzing the mechanical stability of the site. Several phenomena of relevance for copper corrosion in a repository environment have been investigated. For Reference Case conditions and regardless of flow variability, output is dominated by I-129, which, for a single canister, may give rise to drinking water well doses in the order of 10{sup -6}Sv/yr. Finally, it appears that the procedures involved in the development of influence diagrams may be a promising tool for quality assurance of performance assessments.« less

Young Investigator Challenge: Building an ultrasound-guided FNA clinic-our 5-year experience: From project to practice.

PubMed

Rafael, Oana C; Klein, Melissa; Serbonich, Melissa M; Vadalia, Bhumika; Das, Kasturi; Gimenez, Cecilia E

2017-03-01

The authors' fine-needle aspiration (FNA) clinic opened in 2010, allowing cytopathologists to increase their proficiency and experience in FNA performance. Here, they report their 5-year experience. The FNA clinic log book and the institution's database were retrospectively reviewed to record patients' demographics, the number of FNAs performed per year by each cytopathologist, the number of passes, rapid on-site evaluation (ROSE) and diagnosis, adequacy-diagnosis concordance, and follow-up histology when available. The numbers and types of cases per year and variations among cytopathologists were compared. In total, 474 cases were identified within a 5-year time-frame. The discrepancy rate between the on-site and final diagnoses decreased progressively, from 4.4% to 2.4%. The nondiagnostic rate decreased from 2011 to 2015, with the exception of 2014, when an increase was noted, possibly because of a lower number of cases. Cytopathologists' performance was assessed over a 3-year period. The number of passes for each FNA decreased over time. The cytology-histology concordance was 100% over time for all cytopathologists. There was a diagnostic discrepancy between the ROSE and final diagnoses for 3 of 104 cases in 2013 and for 3 of 124 cases in 2015. The total number of passes was not consistently recorded until 2014, when a final report template was instituted. The technique improved over time because of accumulated experience, constant practice with phantoms, and attending the College of American Pathologists' training in ultrasound-guided FNA. FNAs performed by cytopathologists have a high-rate of ROSE/adequacy and a low diagnostic discrepancy rate. Cytopathologists as interventionalists provide optimal care and excellent patient satisfaction. Cancer Cytopathol 2017;125:161-168. © 2016 American Cancer Society. © 2017 American Cancer Society.

Eeap-lighting survey study at the Red River Army Depot Texarkana, Texas. Final report, 17 October 1994-14 April 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pieper, C.A.; Luckett, T.

This energy conservation study was performed by Huitt-Zollars Inc, for the U.S. Army Engineer District (USAED), Fort Worth, under contract number DACAC63-94-D-00l5. The study was conducted at Red River Army Depot (RRAD) in Texarkana, Texas, between October 17, 1994 and April 14, 1995. The site survey and data collection were performed by C.A. Pieper, P.E. and Tom Luckett, Lighting Designer. The purpose of the study was to perform a limited site survey of specific buildings at the facility, identify Conservation Opportunities (ECOs) that exist, and then evaluate these ECOs for technical and economic feasibility. These ECOs were limited to buildingmore » interior lighting and it`s effects on the heating, ventilating and air conditioning (HVAC) systems.« less

Using site-selection model to identify suitable sites for seagrass transplantation in the west coast of South Sulawesi

NASA Astrophysics Data System (ADS)

Lanuru, Mahatma; Mashoreng, S.; Amri, K.

2018-03-01

The success of seagrass transplantation is very much depending on the site selection and suitable transplantation methods. The main objective of this study is to develop and use a site-selection model to identify the suitability of sites for seagrass (Enhalus acoroides) transplantation. Model development was based on the physical and biological characteristics of the transplantation site. The site-selection process is divided into 3 phases: Phase I identifies potential seagrass habitat using available knowledge, removes unnecessary sites before the transplantation test is performed. Phase II involves field assessment and transplantation test of the best scoring areas identified in Phase I. Phase III is the final calculation of the TSI (Transplant Suitability Index), based on results from Phases I and II. The model was used to identify the suitability of sites for seagrass transplantation in the West coast of South Sulawesi (3 sites at Labakkang Coast, 3 sites at Awerange Bay, and 3 sites at Lale-Lae Island). Of the 9 sites, two sites were predicted by the site-selection model to be the most suitable sites for seagrass transplantation: Site II at Labakkang Coast and Site III at Lale-Lae Island.

Site operator program final report for fiscal years 1992 through 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Francfort, J.E.; Bassett, R.R.; Birasco, S.

The Site Operator Program was an electric vehicle testing and evaluation program sponsored by US Department of Energy and managed at the Idaho National Engineering and Environmental Laboratory. The Program`s goals included the field evaluation of electric vehicles in real-world applications and environments; the support of electric vehicle technology advancement; the development of infrastructure elements necessary to support significant electric vehicle use; and increasing the awareness and acceptance of electric vehicles. This report covers Program activities from 1992 to 1996. The Site Operator Program ended in September 1996, when it was superseded by the Field Operations Program. Electric vehicle testingmore » included baseline performance testing, which was performed in conjunction with EV America. The baseline performance parameters included acceleration, braking, range, energy efficiency, and charging time. The Program collected fleet operations data on electric vehicles operated by the Program`s thirteen partners, comprising electric utilities, universities, and federal agencies. The Program`s partners had over 250 electric vehicles, from vehicle converters and original equipment manufacturers, in their operating fleets. Test results are available via the World Wide Web site at http://ev.inel.gov/sop.« less

Final Technical Report: Increasing Prediction Accuracy.

DOE Office of Scientific and Technical Information (OSTI.GOV)

King, Bruce Hardison; Hansen, Clifford; Stein, Joshua

2015-12-01

PV performance models are used to quantify the value of PV plants in a given location. They combine the performance characteristics of the system, the measured or predicted irradiance and weather at a site, and the system configuration and design into a prediction of the amount of energy that will be produced by a PV system. These predictions must be as accurate as possible in order for finance charges to be minimized. Higher accuracy equals lower project risk. The Increasing Prediction Accuracy project at Sandia focuses on quantifying and reducing uncertainties in PV system performance models.

Effect of Cation Ordering on the Performance and Chemical Stability of Layered Double Perovskite Cathodes

PubMed Central

Bernuy-Lopez, Carlos; Rioja-Monllor, Laura; Nakamura, Takashi; Ricote, Sandrine; O’Hayre, Ryan; Amezawa, Koji; Einarsrud, Mari-Ann

2018-01-01

The effect of A-site cation ordering on the cathode performance and chemical stability of A-site cation ordered LaBaCo2O5+δ and disordered La0.5Ba0.5CoO3−δ materials are reported. Symmetric half-cells with a proton-conducting BaZr0.9Y0.1O3−δ electrolyte were prepared by ceramic processing, and good chemical compatibility of the materials was demonstrated. Both A-site ordered LaBaCo2O5+δ and A-site disordered La0.5Ba0.5CoO3−δ yield excellent cathode performance with Area Specific Resistances as low as 7.4 and 11.5 Ω·cm2 at 400 °C and 0.16 and 0.32 Ω·cm2 at 600 °C in 3% humidified synthetic air respectively. The oxygen vacancy concentration, electrical conductivity, basicity of cations and crystal structure were evaluated to rationalize the electrochemical performance of the two materials. The combination of high-basicity elements and high electrical conductivity as well as sufficient oxygen vacancy concentration explains the excellent performance of both LaBaCo2O5+δ and La0.5Ba0.5CoO3−δ materials at high temperatures. At lower temperatures, oxygen-deficiency in both materials is greatly reduced, leading to decreased performance despite the high basicity and electrical conductivity. A-site cation ordering leads to a higher oxygen vacancy concentration, which explains the better performance of LaBaCo2O5+δ. Finally, the more pronounced oxygen deficiency of the cation ordered polymorph and the lower chemical stability at reducing conditions were confirmed by coulometric titration. PMID:29373541

Antibody-mediated cofactor-driven reactions

DOEpatents

Schultz, Peter G.

1993-01-01

Chemical reactions capable of being rate-enhanced by auxiliary species which interact with the reactants but do not become chemically bound to them in the formation of the final product are performed in the presence of antibodies which promote the reactions. The antibodies contain regions within their antigen binding sites which recognize the auxiliary species in a conformation which promotes the reaction. The antigen binding site frequently recognizes a particular transition state complex or other high energy complex along the reaction coordinate, thereby promoting the progress of the reaction along the desired route as opposed to other less favorable routes. Various classes of reaction together with appropriate antigen binding site specificities tailored for each are disclosed.

Determination of optimum mounting configurations for flat-plate photovoltaic modules based on a structured field experiment and simulated results from PVFORM, a photovoltaic system performance model

NASA Astrophysics Data System (ADS)

Menicucci, D. F.

1986-01-01

The performance of a photovoltaic (PV) system is affected by its mounting configuration. The optimal configuration is unclear because of lack of experience and data. Sandia National Laboratories, Albuquerque (SNLA), has conducted a controlled field experiment to compare four types of the most common module mounting. The data from the experiment were used to verify the accuracy of PVFORM, a new computer program that simulates PV performance. PVFORM was then used to simulate the performance of identical PV modules on different mounting configurations at 10 sites throughout the US. This report describes the module mounting configurations, the experimental methods used, the specialized statistical techniques used in the analysis, and the final results of the effort. The module mounting configurations are rank ordered at each site according to their annual and seasonal energy production performance, and each is briefly discussed in terms of its advantages and disadvantages in various applications.

Advanced Global Atmospheric Gases Experiment (AGAGE)

NASA Technical Reports Server (NTRS)

Prinn, Ronald G.

2001-01-01

AGAGE comprises continuous high frequency in-situ gas chromatographic FID/ECD measurements of two biogenic/anthropogenic gases (CH4, N2O) and five anthropogenic gases (CFCl3, CF2Cl2, CH3CCl3, CF2ClCFCl2, CCl4) which are carried out at five globally distributed sites (Ireland, California, Barbados, Samoa, Tasmania). Also, high frequency in-situ gas-chromatographic mass spectrometric measurements of about 30 species including chlorofluorocarbon replacements and many natural halocarbons are made at two sites (Ireland, Tasmania), and will soon begin at the other three sites. Finally, high frequency in-situ gas chromatographic HgO-RD measurements of CO and H2 are performed at two sites (Ireland, Tasmania). The goal is quantitative determination of the sources, sinks, and circulation of these environmentally important gases.

Project EXCEL. Final Performance Report, March 1, 1991-October 31, 1992.

ERIC Educational Resources Information Center

Career Resources Development Center, Inc., San Francisco, CA.

Project EXCEL is a workplace literacy project involving four small business enterprises in San Francisco. Over a 19-month period, the project focused on literacy and basic skills training for 271 limited-English-proficient (LEP) workers. All training was conducted at the work sites, and a variety of support services were provided, including…

Research Turbine Leaves Legacy in Its Wake | News | NREL

Science.gov Websites

110. Two 340-foot cranes were needed to install the larger, 175-foot blades optimized for intermediate depending, to remove the blades, then the nacelle, and finally the tower, section by section. "Site operating the turbine, but also performing complex procedures-like changing out blades that weigh more than

76 FR 23286 - New Pneumatic Off-the-Road Tires From the People's Republic of China: Final Results of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-26

... sites. They can also be used to perform ``rough grading'' in road construction. \\10\\ A straddle carrier... commonly used in maintenance of unpaved roads and road construction to prepare the base course onto which... DEPARTMENT OF COMMERCE International Trade Administration [C-570-913] New Pneumatic Off-the-Road...

Superfund record of decision (EPA Region 5): Skinner Landfill, West Chester, OH, June 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-06-04

The decision document presents the selected final remedial action for the Skinner Landfill site in West Chester, Ohio. The remedy is the second and final of two operable units for this site. The first operable unit addressed immediate site concerns, through the construction of a fence around the contaminated area, and by offering an alternate supply of drinking water to the potentially affected users of groundwater. This final operable unit addresses potential future migration of site contaminants into the groundwater and will limit the potential for direct exposure of site contaminants to humans through source control measures.

78 FR 1143 - Explosive Siting Requirements; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

... launch site operators in site planning for the storage and handling of energetic liquids and explosives...: For technical questions concerning this final rule, contact Yvonne Tran, Commercial Space... this final rule, contact Laura Montgomery, AGC 200, [[Page 1144

Academic procrastination and academic performance: An initial basis for intervention.

PubMed

Goroshit, Marina

2018-01-01

Academic procrastination is a prevalent phenomenon with a range of negative outcomes. Many studies focused on causes and correlates of academic procrastination; however, the study of interventions for academic procrastination is scarce. The present study is an initial effort to study the relationship between academic procrastination, online course participation, and achievement, as a basis for developing an intervention for academic procrastination. Findings indicated that studying procrastination was negatively associated with final exam grade as well as with the three online course participation measures. Final exam grade was positively associated with two of the online course participation measures, and they positively correlated with each other. In addition, results indicated that studying procrastination, in combination with online course participation measures, explained about 50% of variance in final exam's grade. Frequency of activities in course Web site had the strongest positive effect on final exam's grade. These findings strengthen the notion that studying procrastination is an impediment to students' academic performance and outcomes and clarifies the need to develop and study academic interventions for academic procrastination as a means to decrease its prevalence in academic settings.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baxter, Van D.; Munk, Jeffrey D.; Gehl, Anthony C.

The field study is planned to continue through the 2016 cooling season with the draft final project report due by September 30, 2016. This report provides a description of both installations and preliminary 2015 cooling and fall season performance results for the Knoxville site. For the August 18 through December 14 period, the Knoxville site GS-IHP provided 53.6% total source energy savings compared to a baseline electric RTU/heat pump and electric WH. Peak demand savings ranged from 33% to 59% per month. Energy cost savings of 53.1% have been achieved to date with more than half of that coming frommore » reduced demand charges. Data on installation and maintenance costs are being collected and will be combined with total test period energy savings data for a payback analysis to be included in the project final report. The GS-IHP also saved a significant amount of carbon emissions. The total emission savings for the Knoxville site for the August-December 2015 period were ~0.8 metric tons. If trading for carbon credits ever becomes a reality, additional cost savings would be realized.« less

Wastewater characterization survey, Edwards Air Force Base, California. Final report, 17-28 February 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCoy, R.P.

1992-08-01

A wastewater characterization survey was conducted at Edwards Air Force Base from 17-28 February 1992 by personnel from the Water Quality Function of Armstrong Laboratory. Extensive sampling of the treatment plant influent wastewater and sludge beds was performed as well as sampling at nine other sites in the base cantonment area. Some sampling of an Imhoff tank on North Base, five evaporation ponds and the lakebed was also conducted. Low levels of organic contamination were found in the influent and industrial sites downstream of Site 7. Site 7 is a manhole located in an identified Installation Restoration Program (IRP) site.more » Corrective actions were recommended to prevent organic soil contaminants from intruding into this site prior to the operation of a planned tertiary treatment plant. Organic and inorganic contaminants discharged at other industrial sites were found to be in low concentrations and indicated that good shop practices were followed in minimizing contamination of the wastewater with industrial chemicals.« less

Installation restoration program. Site investigation report. Revision 4. Volume 2: Appendix B through Appendix E. 155th Air Refueling Group, Nebraska Air National Guard, Lincoln Municipal Airport, Lincoln, Nebraska. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-04-01

This is Site investigation Report, Volume 2 Appendix B through E. A Site Investigation was performed at the 155th Air Refueling Group at Lincoln, NE to evaluate six areas of suspected contamination identified during a Preliminary Assessment. The sites that this investigation were conducted at are: Site 1 - Fuel Farm, POL Storage Area Site 2 - West End of Old Oak Creek, Site 3 - Former Tank Cleaning/Hazardous Waste Storage Area, Site 4 - Access Road, Dust Control Area, Site 5 - Army National Guard Oil Storage Area, and Site 6 - Hydraulic Pressure Check Unit Storage Area. Themore » report recommended no further action for Sites 3 through 6 due to low levels or no contamination being found. The report recommended that the portion of Site 2 that is located downstream of Site 1 should be included in Site 1. Appendix 2 consist of the following appendix: Well Data and Geologic Boring Logs (Appendix B), Survey Data (Appendix C), Quality Control (Appendix D), and Analytical Results (Appendix E).« less

Study of emissions from passenger cars in six cities, FY79. Volume I. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-10-01

The standard mass emission test (Federal Test Procedure) was performed for emission factors determination on samples of passenger cars operating in Los Angeles, Houston, Denver, Phoenix, St. Louis and Washington, DC. These samples were also used for obtaining abbreviated emission test (short cycle test), fuel economy test, emission related maintenance and other data. Two-thousand forty-two (2,042) vehicles were tested under the program. The FTP and the Highway Fuel Economy Test were performed on all vehicles at all sites. Some vehicles which exceed Federal standards (excluding the Houston site) were subjected to a restorative maintenance evaluation. The evaluation employed in Losmore » Angeles was designed to address three-way catalyst technology. Some vehicles in all but the Los Angeles site were used to evaluate commercial repair facility performance in relation to idle speed and mixture adjustments. Other actions were taken in relation to each vehicle tested. These included an emission control system maladjustment/disablement and status inspection driveability evaluations and owner interviews to obtain vehicle maintenance and usage data.« less

Solar Technology Validation Project - USS Data, LLC: Cooperative Research and Development Final Report, CRADA Number CRD-09-367-04

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilcox, S.

2013-08-01

Under this Agreement, NREL will work with Participant to improve concentrating solar power system performance characterizations. This work includes, but is not limited to, research and development of methods for acquiring renewable resource characterization information using site-specific measurements of solar radiation and meteorological conditions; collecting system performance data; and developing tools for improving the design, installation, operation, and maintenance of solar energy conversion systems. This work will be conducted at NREL and Participant facilities.

Solar Technology Validation Project - RES Americas: Cooperative Research and Development Final Report, CRADA Number CRD-09-367-11

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilcox, S.

Under this Agreement, NREL will work with Participant to improve concentrating solar power system performance characterizations. This work includes, but is not limited to, research and development of methods for acquiring renewable resource characterization information using site-specific measurements of solar radiation and meteorological conditions; collecting system performance data; and developing tools for improving the design, installation, operation, and maintenance of solar energy conversion systems. This work will be conducted at NREL and Participant facilities.

Offshore Wind Guidance Document: Oceanography and Sediment Stability (Version 1) Development of a Conceptual Site Model.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberts, Jesse D.; Jason Magalen; Craig Jones

This guidance document provide s the reader with an overview of the key environmental considerations for a typical offshore wind coastal location and the tools to help guide the reader through a thoro ugh planning process. It will enable readers to identify the key coastal processes relevant to their offshore wind site and perform pertinent analysis to guide siting and layout design, with the goal of minimizing costs associated with planning, permitting , and long - ter m maintenance. The document highlight s site characterization and assessment techniques for evaluating spatial patterns of sediment dynamics in the vicinity of amore » wind farm under typical, extreme, and storm conditions. Finally, the document des cribe s the assimilation of all of this information into the conceptual site model (CSM) to aid the decision - making processes.« less

Final Report Feasibility Study for the California Wave Energy Test Center (CalWavesm) - Volume #2 - Appendices #16-17

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dooher, Brendan; Toman, William I.; Davy, Doug M.

The California Wave Energy Test Center (CalWave) Feasibility Study project was funded over multiple phases by the Department of Energy to perform an interdisciplinary feasibility assessment to analyze the engineering, permitting, and stakeholder requirements to establish an open water, fully energetic, grid connected, wave energy test center off the coast of California for the purposes of advancing U.S. wave energy research, development, and testing capabilities. Work under this grant included wave energy resource characterization, grid impact and interconnection requirements, port infrastructure and maritime industry capability/suitability to accommodate the industry at research, demonstration and commercial scale, and macro and micro sitingmore » considerations. CalWave Phase I performed a macro-siting and down-selection process focusing on two potential test sites in California: Humboldt Bay and Vandenberg Air Force Base. This work resulted in the Vandenberg Air Force Base site being chosen as the most favorable site based on a peer reviewed criteria matrix. CalWave Phase II focused on four siting location alternatives along the Vandenberg Air Force Base coastline and culminated with a final siting down-selection. Key outcomes from this work include completion of preliminary engineering and systems integration work, a robust turnkey cost estimate, shoreside and subsea hazards assessment, storm wave analysis, lessons learned reports from several maritime disciplines, test center benchmarking as compared to existing international test sites, analysis of existing applicable environmental literature, the completion of a preliminary regulatory, permitting and licensing roadmap, robust interaction and engagement with state and federal regulatory agency personnel and local stakeholders, and the population of a Draft Federal Energy Regulatory Commission (FERC) Preliminary Application Document (PAD). Analysis of existing offshore oil and gas infrastructure was also performed to assess the potential value and re-use scenarios of offshore platform infrastructure and associated subsea power cables and shoreside substations. The CalWave project team was well balanced and was comprised of experts from industry, academia, state and federal regulatory agencies. The result of the CalWave feasibility study finds that the CalWave Test Center has the potential to provide the most viable path to commercialization for wave energy in the United States.« less

Remedial Action Plan and site design for stabilization of the inactive uranium mill tailings site at Durango, Colorado: Attachment 2, Geology report. Revised final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-12-01

Detailed investigations of geologic, geomorphic, and seismic conditions at the Bodo Canyon disposal site were conducted. The purpose of these investigations was basic site characterization and identification of potential geologic hazards that could affect long-term site stability. Subsequent engineering studies, such as analyses of hydrologic and liquefaction hazards, used the data developed in these studies. The geomorphic analysis was employed in the design of effective erosion protection. Studies of the regional and local seismotectonic setting, which included a detailed search for possible capable faults within a 65 kilometer radius of the site, provided the basis for seismic design parameters. Themore » scope of work performed included the following: Compilation and analysis of previous published and unpublished geologic literature and maps; Review of historical and instrumental earthquake data; Review of site-specific subsurface geologic data, including lithologic and geophysical logs of exploratory boreholes advanced in the site area; Photogeologic interpretations of existing conventional aerial photographs; and, Ground reconnaissance and mapping of the site region.« less

Napsin A levels in epithelial lining fluid as a diagnostic biomarker of primary lung adenocarcinoma.

PubMed

Uchida, Akifumi; Samukawa, Takuya; Kumamoto, Tomohiro; Ohshige, Masahiro; Hatanaka, Kazuhito; Nakamura, Yoshihiro; Mizuno, Keiko; Higashimoto, Ikkou; Sato, Masami; Inoue, Hiromasa

2017-12-12

It is crucial to develop novel diagnostic approaches for determining if peripheral lung nodules are malignant, as such nodules are frequently detected due to the increased use of chest computed tomography scans. To this end, we evaluated levels of napsin A in epithelial lining fluid (ELF), since napsin A has been reported to be an immunohistochemical biomarker for histological diagnosis of primary lung adenocarcinoma. In consecutive patients with indeterminate peripheral lung nodules, ELF samples were obtained using a bronchoscopic microsampling (BMS) technique. The levels of napsin A and carcinoembryonic antigen (CEA) in ELF at the nodule site were compared with those at the contralateral site. A final diagnosis of primary lung adenocarcinoma was established by surgical resection. We performed BMS in 43 consecutive patients. Among patients with primary lung adenocarcinoma, the napsin A levels in ELF at the nodule site were markedly higher than those at the contralateral site, while there were no significant differences in CEA levels. Furthermore, in 18 patients who were undiagnosed by bronchoscopy and finally diagnosed by surgery, the napsin A levels in ELF at the nodule site were identically significantly higher than those at the contralateral site. In patients with non-adenocarcinoma, there were no differences in napsin A levels in ELF. The area under the receiver operator characteristic curve for identifying primary lung adenocarcinoma was 0.840 for napsin A and 0.542 for CEA. Evaluation of napsin A levels in ELF may be useful for distinguishing primary lung adenocarcinoma.

A new extranodal scoring system based on the prognostically relevant extranodal sites in diffuse large B-cell lymphoma, not otherwise specified treated with chemoimmunotherapy.

PubMed

Hwang, Hee Sang; Yoon, Dok Hyun; Suh, Cheolwon; Huh, Jooryung

2016-08-01

Extranodal involvement is a well-known prognostic factor in patients with diffuse large B-cell lymphomas (DLBCL). Nevertheless, the prognostic impact of the extranodal scoring system included in the conventional international prognostic index (IPI) has been questioned in an era where rituximab treatment has become widespread. We investigated the prognostic impacts of individual sites of extranodal involvement in 761 patients with DLBCL who received rituximab-based chemoimmunotherapy. Subsequently, we established a new extranodal scoring system based on extranodal sites, showing significant prognostic correlation, and compared this system with conventional scoring systems, such as the IPI and the National Comprehensive Cancer Network-IPI (NCCN-IPI). An internal validation procedure, using bootstrapped samples, was also performed for both univariate and multivariate models. Using multivariate analysis with a backward variable selection, we found nine extranodal sites (the liver, lung, spleen, central nervous system, bone marrow, kidney, skin, adrenal glands, and peritoneum) that remained significant for use in the final model. Our newly established extranodal scoring system, based on these sites, was better correlated with patient survival than standard scoring systems, such as the IPI and the NCCN-IPI. Internal validation by bootstrapping demonstrated an improvement in model performance of our modified extranodal scoring system. Our new extranodal scoring system, based on the prognostically relevant sites, may improve the performance of conventional prognostic models of DLBCL in the rituximab era and warrants further external validation using large study populations.

Stressor Identification (Si) at Contaminated Sites: Upper Arkansas River, Colorado (Final)

EPA Science Inventory

EPA announced the availability of the final report, Stressor Identification (SI) at Contaminated Sites: Upper Arkansas River, Colorado. This report describes a causal assessment for impairments of plant growth and plant species richness at a terrestrial contaminated site ...

A Model Vocational High Technology in Health Care Demonstration Project. Final Performance Report.

ERIC Educational Resources Information Center

Valencia Community Coll., Orlando, FL.

A unique training program in high tech obstetrical, neonatal, and pediatric nursing care areas was designed to be offered on site at Orlando (Florida) Regional Medical/Arnold Palmer Hospital for Children and Women. The training program offered 16 different courses to 355 employees over the 18-month period of the project. A needs assessment was…

Materials Technology: The Common Core Skills That are Shaping the Future. Final Performance Report. January 1, 1989-June 30, 1990.

ERIC Educational Resources Information Center

Battelle Pacific Northwest Laboratories, Richland, WA.

A materials technology program was developed at Richland High School (Washington) and pilot tested at seven sites in Washington and Oregon. The program created partnerships between science and vocational education teachers at Richland High and Battelle Pacific Northwest Laboratories, and was then expanded to include other high schools, colleges,…

Using PVFORM, a systems performance model, to determine optimum mounting configurations for flat-plate photovoltaic modules

NASA Astrophysics Data System (ADS)

Menicucci, D. F.

The performance of a photovoltaic (PV) system is affected by the particular mounting configuration selected. But the optimal configuration for various potential designs is unknown because too few PV systems have been fielded. Sandia National Laboratories (SNLA) is currently conducting a controlled field experiment in which four of the most commonly used module mounting configurations are being compared. The data from the experiment are used to verify the accuracy of PVFORM, a new PV performance model. The model is then used to simulate the performance of PV modules mounted in different configurations in eight sites throughtout the U.S. The module mounting configurations, the experimental methods used, the specialized statistical techniques used in the analysis and the final results of the effort are described. The module mounting configurations are rank ordered at each site according to their energy production performane and each is briefly discussed in terms of its advantages or disadvantages in various applications.

Baseline Ecological Risk Assessment for the Upland at the LCP Chemical Site, Brunswick, Georgia - Site Investigation/Analysis and Risk Characterization (Final)

EPA Pesticide Factsheets

Site Investigation/Analysis and Risk Characterization (Final) Prepared for Honeywell International Inc. Prepared by CDR Environmental Specialists, Inc. August 2010 Region ID: 04 DocID: 10746263, DocDate: 08-01-2010

Rapid on-site evaluation with the Hemacolor rapid staining method of medical thoracoscopy biopsy specimens for the management of pleural disease.

PubMed

Porfyridis, Ilias; Georgiadis, Georgios; Michael, Michalis; Frangopoulos, Frangiskos; Vogazianos, Paris; Papadopoulos, Alexis; Kara, Panayiota; Charalampous, Charis; Georgiou, Andreas

2016-08-01

Medical thoracoscopy (MT) is useful for the management of pleural disease. Rapid on-site evaluation (ROSE) of transbronchial needle aspirates proved to be useful during bronchoscopy. We aimed to evaluate the diagnostic performance of ROSE of MT biopsy specimens and thoracoscopists' impression of the macroscopic appearance and assess the intermodality agreement between ROSE and final histopathologic diagnosis. Sixty two patients with exudative pleural effusions further investigated with MT were enrolled. MT was performed under local anaesthesia and conscious sedation, using the rigid pleuroscope. ROSE with the Hemacolor rapid staining method of the biopsy specimens was performed. Thoracoscopists' impression of the macroscopic appearance was recorded. The final diagnosis was established following histopathological examination. Thoracoscopic pleural biopsies were diagnosed in 61 patients (98.4%). Group A (n = 25) consisted of patients with malignancy and group B (n = 37) with benign disorders. Area under the curve of ROSE for the diagnosis of malignancy was 0.86 (95% CI: 0.76-0.96, P < 0.001), with a sensitivity of 79.17%, specificity of 94.59%, diagnostic accuracy of 88.5%, positive predictive value of 90.5% and negative predictive value of 87.5%. Intermodality agreement between ROSE and histopathology was good (κ ± SE = 0.615 ± 0.084, P < 0.001). Area under the curve of the thoracoscopists' impression of macroscopic appearance was 0.72 (95% CI: 0.58-0.85, P = 0.001), with a sensitivity of 100%, specificity of 44.7%, positive predictive value of 53.33% and negative predictive value of 100%. Rapid on-site evaluation during MT was found to have high accuracy for predicting malignancy. ROSE can provide the thoracoscopist with an on-site preliminary diagnosis, especially in cases with inconclusive macroscopic appearance. © 2016 Asian Pacific Society of Respirology.

Development of a Method for Selecting Optimum Sites for the Automatic Mountain Meteorology Observation Station (AMOS) to Improve Predictability of Forest Fires in Inaccessible Area

NASA Astrophysics Data System (ADS)

Yoon, S.; Won, M.; Jang, K.; Lim, J.

2016-12-01

As there has been a recent increase in the case of forest fires in North Korea descending southward through the De-Militarized Zone (DMZ), ensuring proper response to such events has been a challenge. Therefore, in order to respond and manage these forest fires appropriately, an improvement in the forest fire predictability through integration of mountain weather information observed at the most optimal site is necessary. This study is a proactive case in which a spatial analysis and an on-site assessment method were developed for selecting an optimum site for a mountain weather observation in national forest. For spatial analysis, the class 1 and 2 forest fire danger areas for the past 10 years, accessibility maximum 100m, Automatic Weather Station (AWS) redundancy within 2.5km, and mountain terrains higher than 200m were analyzed. A final overlay analysis was performed to select the candidates for the field assessment. The sites selected through spatial analysis were quantitatively evaluated based on the optimal meteorological environment, forest and hiking trail accessibility, AWS redundancy, and supply of wireless communication and solar powered electricity. The sites with total score of 70 and higher were accepted as adequate. At the final selected sites, an AMOS was established, and integration of mountain and Korea Meteorological Administration (KMA) weather data improved the forest fire predictability in South Korea by 10%. Given these study results, we expect that establishing an automatic mountain meteorology observation station at the optimal sites in inaccessible area and integrating mountain weather data will improve the predictability of forest fires.

Mars Pathfinder Atmospheric Entry Navigation Operations

NASA Technical Reports Server (NTRS)

Braun, R. D.; Spencer, D. A.; Kallemeyn, P. H.; Vaughan, R. M.

1997-01-01

On July 4, 1997, after traveling close to 500 million km, the Pathfinder spacecraft successfully completed entry, descent, and landing, coming to rest on the surface of Mars just 27 km from its target point. In the present paper, the atmospheric entry and approach navigation activities required in support of this mission are discussed. In particular, the flight software parameter update and landing site prediction analyses performed by the Pathfinder operations navigation team are described. A suite of simulation tools developed during Pathfinder's design cycle, but extendible to Pathfinder operations, are also presented. Data regarding the accuracy of the primary parachute deployment algorithm is extracted from the Pathfinder flight data, demonstrating that this algorithm performed as predicted. The increased probability of mission success through the software parameter update process is discussed. This paper also demonstrates the importance of modeling atmospheric flight uncertainties in the estimation of an accurate landing site. With these atmospheric effects included, the final landed ellipse prediction differs from the post-flight determined landing site by less then 0.5 km in downtrack.

77 FR 16558 - General Management Plan/Final Environmental Impact Statement, Hampton National Historic Site...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-21

... Management Plan/Final Environmental Impact Statement, Hampton National Historic Site, Maryland AGENCY...) announces the availability of the Final Environmental Impact Statement for the General Management Plan.../Baltimore County Library, 320 York Avenue, Towson, Maryland 21204. Baltimore County Tourism Office and...

White paper updating conclusions of 1998 ILAW performance assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

MANN, F.M.

The purpose of this document is to provide a comparison of the estimated immobilized low-activity waste (LAW) disposal system performance against established performance objectives using the beat estimates for parameters and models to describe the system. The principal advances in knowledge since the last performance assessment (known as the 1998 ILAW PA [Mann 1998a]) have been in site specific information and data on the waste form performance for BNFL, Inc. relevant glass formulations. The white paper also estimates the maximum release rates for technetium and other key radionuclides and chemicals from the waste form. Finally, this white paper provides limitedmore » information on the impact of changes in waste form loading.« less

Xenogeneic collagen matrix versus connective tissue graft for buccal soft tissue augmentation at implant site. A randomized, controlled clinical trial.

PubMed

Cairo, Francesco; Barbato, Luigi; Tonelli, Paolo; Batalocco, Guido; Pagavino, Gabriella; Nieri, Michele

2017-07-01

Peri-implant soft tissue may be critical to prevent inflammation and promote gingival margin stability. The purpose of this randomized clinical trial (RCT) is to compare xenogeneic collagen matrix (XCM) versus connective tissue graft (CTG) to increase buccal soft tissue thickness at implant site. Soft tissue augmentation with XCM (test) or CTG (control) was performed at 60 implants in 60 patients at the time of implant uncovering. Measurements were performed by a blinded examiner at baseline, 3 and 6 months. Outcome measures included buccal soft tissue thickness (GT), apico-coronal keratinized tissue (KT), chair time and post-operative discomfort. Visual Analogue Scale (VAS) was used to evaluate patient satisfaction. After 6 months, the final GT increase was 0.9 ± 0.2 in the XCM group and 1.2 ± 0.3 mm in the CTG group, with a significant difference favouring the control group (0.3 mm; p = .0001). Both procedures resulted in similar final KT amount with no significant difference between treatments. XCM was associated with significant less chair-time (p < .0001), less post-operative pain (p < .0001), painkillers intake (p < .0001) and higher final satisfaction than CTG (p = .0195). CTG was more effective than XCM to increase buccal peri-implant soft tissue thickness. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Development of a brachytherapy audit checklist tool.

PubMed

Prisciandaro, Joann; Hadley, Scott; Jolly, Shruti; Lee, Choonik; Roberson, Peter; Roberts, Donald; Ritter, Timothy

2015-01-01

To develop a brachytherapy audit checklist that could be used to prepare for Nuclear Regulatory Commission or agreement state inspections, to aid in readiness for a practice accreditation visit, or to be used as an annual internal audit tool. Six board-certified medical physicists and one radiation oncologist conducted a thorough review of brachytherapy-related literature and practice guidelines published by professional organizations and federal regulations. The team members worked at two facilities that are part of a large, academic health care center. Checklist items were given a score based on their judged importance. Four clinical sites performed an audit of their program using the checklist. The sites were asked to score each item based on a defined severity scale for their noncompliance, and final audit scores were tallied by summing the products of importance score and severity score for each item. The final audit checklist, which is available online, contains 83 items. The audit scores from the beta sites ranged from 17 to 71 (out of 690) and identified a total of 7-16 noncompliance items. The total time to conduct the audit ranged from 1.5 to 5 hours. A comprehensive audit checklist was developed which can be implemented by any facility that wishes to perform a program audit in support of their own brachytherapy program. The checklist is designed to allow users to identify areas of noncompliance and to prioritize how these items are addressed to minimize deviations from nationally-recognized standards. Copyright © 2015 American Brachytherapy Society. All rights reserved.

Development of a diatom-based multimetric index for acid mine drainage impacted depressional wetlands.

PubMed

Riato, Luisa; Leira, Manel; Della Bella, Valentina; Oberholster, Paul J

2018-01-15

Acid mine drainage (AMD) from coal mining in the Mpumalanga Highveld region of South Africa has caused severe chemical and biological degradation of aquatic habitats, specifically depressional wetlands, as mines use these wetlands for storage of AMD. Diatom-based multimetric indices (MMIs) to assess wetland condition have mostly been developed to assess agricultural and urban land use impacts. No diatom MMI of wetland condition has been developed to assess AMD impacts related to mining activities. Previous approaches to diatom-based MMI development in wetlands have not accounted for natural variability. Natural variability among depressional wetlands may influence the accuracy of MMIs. Epiphytic diatom MMIs sensitive to AMD were developed for a range of depressional wetland types to account for natural variation in biological metrics. For this, we classified wetland types based on diatom typologies. A range of 4-15 final metrics were selected from a pool of ~140 candidate metrics to develop the MMIs based on their: (1) broad range, (2) high separation power and (3) low correlation among metrics. Final metrics were selected from three categories: similarity to reference sites, functional groups, and taxonomic composition, which represent different aspects of diatom assemblage structure and function. MMI performances were evaluated according to their precision in distinguishing reference sites, responsiveness to discriminate reference and disturbed sites, sensitivity to human disturbances and relevancy to AMD-related stressors. Each MMI showed excellent discriminatory power, whether or not it accounted for natural variation. However, accounting for variation by grouping sites based on diatom typologies improved overall performance of MMIs. Our study highlights the usefulness of diatom-based metrics and provides a model for the biological assessment of depressional wetland condition in South Africa and elsewhere. Copyright © 2017 Elsevier B.V. All rights reserved.

Mod-5A wind turbine generator program design report. Volume 3: Final design and system description, book 2

NASA Technical Reports Server (NTRS)

1984-01-01

The design, development and analysis of the 7.3MW MOD-5A wind turbine generator is documented. The report is divided into four volumes: Volume 1 summarizes the entire MOD-5A program, Volume 2 discusses the conceptual and preliminary design phases, Volume 3 describes the final design of the MOD-5A, and Volume 4 contains the drawings and specifications developed for the final design. Volume 3, book 2 describes the performance and characteristics of the MOD-5A wind turbine generator in its final configuration. The subsystem for power generation, control, and instrumentation subsystems is described in detail. The manufacturing and construction plans, and the preparation of a potential site on Oahu, Hawaii, are documented. The quality assurance and safety plan, and analyses of failure modes and effects, and reliability, availability and maintainability are presented.

Establishing Final Cleanup Decisions for the Hanford Site River Corridor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lerch, J.A.; Sands, J.P.

2007-07-01

A major challenge in the River Corridor Closure Contract is establishing final cleanup decisions for the source operable units in the Hanford Site river corridor. Cleanup actions in the river corridor began in 1994 and have been performed in accordance with a 'bias for action' approach adopted by the Tri-Parties - the U.S. Department of Energy, U.S. Environmental Protection Agency, and Washington State Department of Ecology. This approach enabled early application of cleanup dollars on actual remediation of contaminated waste sites. Consequently, the regulatory framework authorizing cleanup actions at source operable units in the river corridor consists largely of interimmore » action records of decision, which were supported by qualitative risk assessments. Obtaining final cleanup decisions for the source operable units is necessary to determine whether past cleanup actions in the river corridor are protective of human health and the environment and to identify any course corrections that may be needed to ensure that ongoing and future cleanup actions are protective. Because the cleanup actions are ongoing, it is desirable to establish the final cleanup decisions as early as possible to minimize the impacts of any identified course corrections to the present cleanup approach. Development of a strategy to obtain final cleanup decisions for the source operable units in a manner that is responsive to desires for an integrated approach with the groundwater and Columbia River components while maintaining the ability to evaluate each component on its own merit represents a significant challenge. There are many different options for grouping final cleanup decisions, and each involved party or stakeholder brings slightly different interests that shape the approach. Regardless of the selected approach, there are several specific challenges and issues to be addressed before making final cleanup decisions. A multi-agency and contractor working group has been established to address these issues and develop an endorsed strategy. Ultimately, it is anticipated that the Tri-Parties will establish a set of milestones to document pathway selection and define schedule requirements. (authors)« less

Improving site selection in clinical studies: a standardised, objective, multistep method and first experience results.

PubMed

Hurtado-Chong, Anahí; Joeris, Alexander; Hess, Denise; Blauth, Michael

2017-07-12

A considerable number of clinical studies experience delays, which result in increased duration and costs. In multicentre studies, patient recruitment is among the leading causes of delays. Poor site selection can result in low recruitment and bad data quality. Site selection is therefore crucial for study quality and completion, but currently no specific guidelines are available. Selection of sites adequate to participate in a prospective multicentre cohort study was performed through an open call using a newly developed objective multistep approach. The method is based on use of a network, definition of objective criteria and a systematic screening process. Out of 266 interested sites, 24 were shortlisted and finally 12 sites were selected to participate in the study. The steps in the process included an open call through a network, use of selection questionnaires tailored to the study, evaluation of responses using objective criteria and scripted telephone interviews. At each step, the number of candidate sites was quickly reduced leaving only the most promising candidates. Recruitment and quality of data went according to expectations in spite of the contracting problems faced with some sites. The results of our first experience with a standardised and objective method of site selection are encouraging. The site selection method described here can serve as a guideline for other researchers performing multicentre studies. ClinicalTrials.gov: NCT02297581. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Site characterization report for the basalt waste isolation project. Volume II

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1982-11-01

The reference location for a repository in basalt for the terminal storage of nuclear wastes on the Hanford Site and the candidate horizons within this reference repository location have been identified and the preliminary characterization work in support of the site screening process has been completed. Fifteen technical questions regarding the qualification of the site were identified to be addressed during the detailed site characterization phase of the US Department of Energy-National Waste Terminal Storage Program site selection process. Resolution of these questions will be provided in the final site characterization progress report, currently planned to be issued in 1987,more » and in the safety analysis report to be submitted with the License Application. The additional information needed to resolve these questions and the plans for obtaining the information have been identified. This Site Characterization Report documents the results of the site screening process, the preliminary site characterization data, the technical issues that need to be addressed, and the plans for resolving these issues. Volume 2 contains chapters 6 through 12: geochemistry; surface hydrology; climatology, meteorology, and air quality; environmental, land-use, and socioeconomic characteristics; repository design; waste package; and performance assessment.« less

Predicting DNAPL Source Zone and Plume Response Using Site-Measured Characteristics

DTIC Science & Technology

2017-05-19

FINAL REPORT Predicting DNAPL Source Zone and Plume Response Using Site- Measured Characteristics SERDP Project ER-1613 MAY 2017...Final Report 3. DATES COVERED (From - To) 2007 - 2017 4. TITLE AND SUBTITLE PREDICTING DNAPL SOURCE ZONE AND PLUME RESPONSE USING SITE- MEASURED ...historical record of concentration and head measurements , particularly in the near-source region. For each site considered, currently available data

Health assessment for Garden State Cleaners Company, Buena Borough, Atlantic City, New Jersey, Region 2. CERCLIS No. NJD053280160. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-09-28

The Garden State Cleaners Company is a dry cleaning establishment located in Buena Borough, New Jersey. Contaminated wastewater from on-site operations was routinely discharged to on-site soils. Analytical data has described significant soil and ground-water contamination from tetrachloroethylene (PCE) and other volatile organic compounds. Ground-water contamination downgradient (to the south) of the site has required the recommended closing of private wells and the installation of a municipal water supply system. An Administrative Order and Notice of Civil Administrative Penalty Assessment (AO and PSO) were issued to Garden State Cleaners in December 1985, requiring GSC to perform a full RI/FS. Municipalmore » water supplies have been made available to affected residens, but utilization is elective. The site was included on the NPL list in March 1989 and is currently ranked 105 of 108 sites in New Jersey. ATSDR and NJDOH consider the Garden State Cleaners site to be of public health concern. The site is being considered for follow-up health study or evaluation.« less

78 FR 23837 - Cranes and Derricks in Construction: Underground Construction and Demolition

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-23

... report here the results for the entire heavy-and-civil engineering sector and the entire site... in this final rule because employers included in the heavy-and-civil engineering sector, or the site... final rule. This final rule affects two construction sectors: NAICS 237990 (Other Heavy and Civil...

Site Monitoring at the U.C. Observatory of Santa Martina

NASA Astrophysics Data System (ADS)

Gatica, C.; Vanzi, L.; Toledo, I.; Lombardi, G.

2011-11-01

This work presents an astroclimatologic analysis of the UC Santa Martina Observatory site. This site is located near Santiago at latitude 33.3°S, longitude 70.5°W and an altitude of 1492 meters above sea level. The analysis was performed using data of temperature, pressure, humidity, and wind collected with a Davis Net Vantage Pro 2 meteo station in a period from December 2007 to January 2011. We estimated average values for the parameters monitored on different time scales and examined daily as well as seasonal variations. We also estimated the downtime due to clouds average with an 37.23% of nights in 2010, humidity, wind over the period examined. The average relative humidity is 49%, wind is predominantly (24% of time) from southsouthwest with an average speed of 0.6 m/s. Finally, we describe Seeing measurements obtained with a DIMM monitor recently installed in the site.

Atomic and molecular oxygen adsorbed on (111) transition metal surfaces: Cu and Ni

NASA Astrophysics Data System (ADS)

López-Moreno, S.; Romero, A. H.

2015-04-01

Density functional theory is used to investigate the reaction of oxygen with clean copper and nickel [111]-surfaces. We study several alternative adsorption sites for atomic and molecular oxygen on both surfaces. The minimal energy geometries and adsorption energies are in good agreement with previous theoretical studies and experimental data. From all considered adsorption sites, we found a new O2 molecular precursor with two possible dissociation paths on the Cu(111) surface. Cross barrier energies for the molecular oxygen dissociation have been calculated by using the climbing image nudge elastic band method, and direct comparison with experimental results is performed. Finally, the structural changes and adsorption energies of oxygen adsorbed on surface when there is a vacancy nearby the adsorption site are also considered.

Atomic and molecular oxygen adsorbed on (111) transition metal surfaces: Cu and Ni.

PubMed

López-Moreno, S; Romero, A H

2015-04-21

Density functional theory is used to investigate the reaction of oxygen with clean copper and nickel [111]-surfaces. We study several alternative adsorption sites for atomic and molecular oxygen on both surfaces. The minimal energy geometries and adsorption energies are in good agreement with previous theoretical studies and experimental data. From all considered adsorption sites, we found a new O2 molecular precursor with two possible dissociation paths on the Cu(111) surface. Cross barrier energies for the molecular oxygen dissociation have been calculated by using the climbing image nudge elastic band method, and direct comparison with experimental results is performed. Finally, the structural changes and adsorption energies of oxygen adsorbed on surface when there is a vacancy nearby the adsorption site are also considered.

Effect of Simplifying Drilling Technique on Heat Generation During Osteotomy Preparation for Dental Implant.

PubMed

El-Kholey, Khalid E; Ramasamy, Saravanan; Kumar R, Sheetal; Elkomy, Aamna

2017-12-01

To test the hypothesis that there would be no difference in heat production by reducing the number of drills during the implant site preparation relative to conventional drilling sequence. A total of 120 implant site preparations with 3 different diameters (3.6, 4.3, and 4.6 mm) were performed on bovine ribs. Within the same diameter group, half of the preparations were performed by a simplified drilling procedure (pilot drill + final diameter drill) and other half using the conventional drilling protocol (pilot drill followed by graduated series of drills to widen the site). Heat production by different drilling techniques was evaluated by measuring the bone temperature using k-type thermocouple and a sensitive thermometer before and after each drill. Mean for maximum temperature increase during site preparation of the 3.6, 4.3, and 4.6-mm implants was 2.45, 2.60, and 2.95° when the site was prepared by the simplified procedure, whereas it was 2.85, 3.10, and 3.60° for the sites prepared by the conventional technique, respectively. No significant difference in temperature increase was found when implants of the 3 different diameters were prepared either by the conventional or simplified drilling procedure. The simplified drilling technique produced similar amount of heat comparable to the conventional technique that proved the initial hypothesis.

Final report on decommissioning of wells, boreholes, and tiltmeter sites, Gulf Coast Interior Salt Domes of Louisiana

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1989-07-01

In the late 1970s, test holes were drilled in northern Louisiana in the vicinity of Vacherie and Rayburn`s Salt Domes as part of the Department of Energy`s (DOE) National Waste Terminal Storage (NWTS) (rename the Civilian Radioactive Waste Management (CRWM)) program. The purpose of the program was to evaluate the suitability of salt domes for long term storage or disposal of high-level nuclear waste. The Institute for Environmental Studies at Louisiana State University (IES/LSU) and Law Engineering Testing Company (LETCo) of Marietta, Georgia performed the initial field studies. In 1982, DOE awarded a contract to the Earth Technology Corporation (TETC)more » of Long Beach, California to continue the Gulf Coast Salt Dome studies. In 1986, DOE deferred salt domes from further consideration as repository sites. This report describes test well plugging and site abandonment activities performed by SWEC in accordance with Activity Plan (AP) 1--3, Well Plugging and Site Restoration of Work Sites in Louisiana. The objective of the work outlined in this AP was to return test sites to as near original condition as possible by plugging boreholes, removing equipment, regrading, and seeding. Appendices to this report contain forms required by State of Louisiana, used by SWEC to document decommissioning activities, and pertinent documentation related to lease/access agreements.« less

Identifying grasslands suitable for cellulosic feedstock crops in the Greater Platte River Basin: dynamic modeling of ecosystem performance with 250 m eMODIS

USGS Publications Warehouse

Gu, Yingxin; Boyte, Stephen P.; Wylie, Bruce K.; Tieszen, Larry L.

2012-01-01

This study dynamically monitors ecosystem performance (EP) to identify grasslands potentially suitable for cellulosic feedstock crops (e.g., switchgrass) within the Greater Platte River Basin (GPRB). We computed grassland site potential and EP anomalies using 9-year (2000–2008) time series of 250 m expedited moderate resolution imaging spectroradiometer Normalized Difference Vegetation Index data, geophysical and biophysical data, weather and climate data, and EP models. We hypothesize that areas with fairly consistent high grassland productivity (i.e., high grassland site potential) in fair to good range condition (i.e., persistent ecosystem overperformance or normal performance, indicating a lack of severe ecological disturbance) are potentially suitable for cellulosic feedstock crop development. Unproductive (i.e., low grassland site potential) or degraded grasslands (i.e., persistent ecosystem underperformance with poor range condition) are not appropriate for cellulosic feedstock development. Grassland pixels with high or moderate ecosystem site potential and with more than 7 years ecosystem normal performance or overperformance during 2000–2008 are identified as possible regions for future cellulosic feedstock crop development (ca. 68 000 km2 within the GPRB, mostly in the eastern areas). Long-term climate conditions, elevation, soil organic carbon, and yearly seasonal precipitation and temperature are important performance variables to determine the suitable areas in this study. The final map delineating the suitable areas within the GPRB provides a new monitoring and modeling approach that can contribute to decision support tools to help land managers and decision makers make optimal land use decisions regarding cellulosic feedstock crop development and sustainability.

Optimal control theory determination of feasible return-to-launch-site aborts for the HL-20 Personnel Launch System vehicle

NASA Technical Reports Server (NTRS)

Dutton, Kevin E.

1994-01-01

The personnel launch system (PLS) being studied by NASA is a system to complement the space shuttle and provide alternative access to space. The PLS consists of a manned spacecraft launched by an expendable launch vehicle (ELV). A candidate for the manned spacecraft is the HL-20 lifting body. In the event of an ELV malfunction during the initial portion of the ascent trajectory, the HL-20 will separate from the rocket and perform an unpowered return to launch site (RTLS) abort. This work details an investigation, using optimal control theory, of the RTLS abort scenario. The objective of the optimization was to maximize final altitude. With final altitude as the cost function, the feasibility of an RTLS abort at different times during the ascent was determined. The method of differential inclusions was used to determine the optimal state trajectories, and the optimal controls were then calculated from the optimal states and state rates.

Groundwater quality assessment plan for single-shell waste management area B-BX-BY at the Hanford Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

SM Narbutovskih

2000-03-31

Pacific Northwest National Laboratory conducted a first determination groundwater quality assessment at the Hanford Site. This work was performed for the US Department of Energy, Richland Operations Office, in accordance with the Federal Facility Compliance Agreement during the time period 1996--1998. The purpose of the assessment was to determine if waste from the Single-Shell Tank (SST) Waste Management Area (WMA) B-BX-BY had entered the groundwater at levels above the drinking water standards (DWS). The resulting assessment report documented evidence demonstrating that waste from the WMA has, most likely, impacted groundwater quality. Based on 40 CFR 265.93 [d] paragraph (7), themore » owner-operator must continue to make the minimum required determinations of contaminant level and of rate/extent of migrations on a quarterly basis until final facility closure. These continued determinations are required because the groundwater quality assessment was implemented prior to final closure of the facility.« less

FY02 Final Report on Phytoremediation of Chlorinated Ethenes in Southern Sector Sediments of the Savannah River Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brigmon, R..L.

This final report details the operations and results of a 3-year Seepline Phytoremediation Project performed adjacent to Tims Branch, which is located in the Southern Sector of the Savannah River Site (SRS) A/M Area. Phytoremediation is a process where interactions between vegetation, associated microorganisms, and the host substrate combine to effectively degrade contaminated soils, sediments, and groundwater. Phytoremediation is a rapidly developing technology that shows promise for the effective and safe cleanup of certain hazardous wastes. It has the potential to remediate numerous volatile organic compounds (VOCs). Extensive characterization work has demonstrated that two VOCs, tetrachloroethylene (PCE) and trichloroethylene (TCE)more » are the major components of the VOC-contaminated groundwater that is migrating through the Southern Sector and Tims Branch seepline area (WSRC, 1999). The PCE and TCE are chlorinated ethenes (CE), and have been detected in seepline soils and ground water adjacent to the ecologically-sensitive Tims Branch seepline area.« less

Assessing site performance in the Altair study, a multinational clinical trial.

PubMed

Berthon-Jones, Nisha; Courtney-Vega, Kymme; Donaldson, Anna; Haskelberg, Hila; Emery, Sean; Puls, Rebekah

2015-04-08

Reviewing clinical trial site performance identifies strategies to control outcomes. Performance across 5 geographical regions (36 sites across Asia, Australia, Europe, North America and Latin America) was investigated in a study that randomised 322 HIV-infected individuals. Regional performance was compared using descriptive analysis for time to site opening, recruitment, quality of data and laboratory samples. Follow-up consisted of 10 visits (96 weeks), electronic data collection (EDC) within 7 days of a visit and serious adverse events (SAEs) reported within 24 hours of site awareness. Median days to site opening was 250 (188 to 266), ranging from 177 (158 to 200) (Australia) to 265 (205 to 270) (Europe). Median days to ethics and regulatory approval was 182 (120 to 241) and 218 (182 to 341) days, respectively. Within regions, time to approval ranged from 187 (91 to 205) days (Australia) to 276 (175 to 384) days (Europe). Time to first randomisation ranged from 282 (250 to 313) days (Australia) to 426 (420 to 433) days (North America). Recruitment was lower than forecasted in Asia, Australia, Europe and North America at 89%, 77%, 91% and 43%, respectively. The converse was true in Latin America where despite ethics, regulatory and contractual delays, recruitment was 104% of predicted. Median days to EDC was 7 (3 to 16), ranging from 3 (1 to 16) (Asia) to 13 (8 to 14) days (North America). Median days for initial SAE submission to sponsor was 6 (2 to 20), ranging from 4 (2 to 18) (Latin America) to 24 (5 to 46) days (Australia). Sites took longer to submit final reports, overall median of 28 (7 to 91) days, ranging from 7 days (Australia) to 67 (23 to 103) days (Europe). Population availability and time to ethics and regulatory approvals influence recruitment; therefore accurate feasibility assessments are critical to site selection. Time to ethics and regulatory approval may not limit site inclusion if compensated by rapid recruitment. Identifying potential delays and methods for reduction can decrease time and costs for sponsors. Clinical Trials.Gov identifier: NCT00335322. Date of registration: 8 June 2006.

A flight-test and simulation evaluation of the longitudinal final approach and landing performance of an automatic system for a light wing loading STOL aircraft

NASA Technical Reports Server (NTRS)

Brown, S. C.; Hardy, G. H.; Hindson, W. S.

1983-01-01

As part of a comprehensive flight-test program of STOL operating systems for the terminal area, an automatic landing system was developed and evaluated for a light wing loading turboprop aircraft. The aircraft utilized an onboard advanced digital avionics system. Flight tests were conducted at a facility that included a STOL runway site with a microwave landing system. Longitudinal flight-test results were presented and compared with available (basically CTOL) criteria. These comparisons were augmented by results from a comprehensive simulation of the controlled aircraft which included representations of navigation errors that were encountered in flight and atmospheric disturbances. Acceptable performance on final approach and at touchdown was achieved by the autoland (automatic landing) system for the moderate winds and turbulence conditions encountered in flight. However, some touchdown performance goals were marginally achieved, and simulation results suggested that difficulties could be encountered in the presence of more extreme atmospheric conditions. Suggestions were made for improving performance under those more extreme conditions.

Longview Public Library Final Performance Report for Library Services and Construction Act (LCSA) Title VI Library Literacy Program.

ERIC Educational Resources Information Center

Longview Public Library, WA.

Project Read at the Longview (Washington) Public Library conducted a program to maintain and expand the Family Literacy Center to provide a monitored tutoring site and family outreach program for a minimum of 75 adult learners and 40 tutors. Two projects were involved: (1) Project READ focused on adult learners with a one-on-one tutoring approach;…

Remote Excavation of Heavily Contaminated UXO Sites. The Range Master

DTIC Science & Technology

2007-09-05

NUMBER 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 6. AUTHOR(S) 7. PERFORMING ORGANIZATION NAME(S) AND...Master) ESTCP Project UX-200327 ii Final Phase II Report, September 2007 3.5.5 Sampling Plan...Explosive HSP Health and Safety Program HTRW Hazardous, Toxic, and Radioactive Waste HTW Hazardous and Toxic Waste HW Hazardous Waste IAW In

Endoscopic Ultrasound Guided Fine Needle Aspiration Biopsy in Diagnosis of Pancreatic and Peripancreatic Lesions: A Single Center Experience in Korea

PubMed Central

Hwang, Chang Yun; Song, Tae Jun; Moon, Sung-Hoon; Lee, Don; Park, Do Hyun; Seo, Dong Wan; Lee, Sung Koo; Kim, Myung-Hwan

2009-01-01

Background/Aims Although endoscopic ultrasound guided fine needle aspiration (EUS-FNA) has been introduced and its use has been increasing in Korea, there have not been many reports about its performance. The aim of this study was to assess the utility of EUS-FNA without on-site cytopathologist in establishing the diagnosis of solid pancreatic and peripancreatic masses from a single institution in Korea. Methods Medical records of 139 patients who underwent EUS-FNA for pancreatic and peripancreatic solid mass in the year 2007, were retrospectively reviewed. By comparing cytopathologic diagnosis of FNA with final diagnosis, sensitivity, specificity, and accuracy were determined, and factors influencing the accuracy as well as complications were analyzed. Results One hundred twenty out of 139 cases had final diagnosis of malignancy. Sensitivity, specificity, and accuracy of EUS-FNA were 82%, 89%, and 83%, respectively, and positive and negative predictive values were 100% and 46%, respectively. As for factors influencing the accuracy of FNA, lesion size was marginally significant (p-value 0.08) by multivariate analysis. Conclusions EUS-FNA performed without on-site cytopathologist was found to be accurate and safe, and thus EUS-FNA should be a part of the standard management algorithm for pancreatic and peripancreatic mass. PMID:20431733

Web vulnerability study of online pharmacy sites.

PubMed

Kuzma, Joanne

2011-01-01

Consumers are increasingly using online pharmacies, but these sites may not provide an adequate level of security with the consumers' personal data. There is a gap in this research addressing the problems of security vulnerabilities in this industry. The objective is to identify the level of web application security vulnerabilities in online pharmacies and the common types of flaws, thus expanding on prior studies. Technical, managerial and legal recommendations on how to mitigate security issues are presented. The proposed four-step method first consists of choosing an online testing tool. The next steps involve choosing a list of 60 online pharmacy sites to test, and then running the software analysis to compile a list of flaws. Finally, an in-depth analysis is performed on the types of web application vulnerabilities. The majority of sites had serious vulnerabilities, with the majority of flaws being cross-site scripting or old versions of software that have not been updated. A method is proposed for the securing of web pharmacy sites, using a multi-phased approach of technical and managerial techniques together with a thorough understanding of national legal requirements for securing systems.

Alignment-independent comparison of binding sites based on DrugScore potential fields encoded by 3D Zernike descriptors.

PubMed

Nisius, Britta; Gohlke, Holger

2012-09-24

Analyzing protein binding sites provides detailed insights into the biological processes proteins are involved in, e.g., into drug-target interactions, and so is of crucial importance in drug discovery. Herein, we present novel alignment-independent binding site descriptors based on DrugScore potential fields. The potential fields are transformed to a set of information-rich descriptors using a series expansion in 3D Zernike polynomials. The resulting Zernike descriptors show a promising performance in detecting similarities among proteins with low pairwise sequence identities that bind identical ligands, as well as within subfamilies of one target class. Furthermore, the Zernike descriptors are robust against structural variations among protein binding sites. Finally, the Zernike descriptors show a high data compression power, and computing similarities between binding sites based on these descriptors is highly efficient. Consequently, the Zernike descriptors are a useful tool for computational binding site analysis, e.g., to predict the function of novel proteins, off-targets for drug candidates, or novel targets for known drugs.

Chemical Modification in the Design of Immobilized Enzyme Biocatalysts: Drawbacks and Opportunities.

PubMed

Rueda, Nazzoly; Dos Santos, Jose C S; Ortiz, Claudia; Torres, Rodrigo; Barbosa, Oveimar; Rodrigues, Rafael C; Berenguer-Murcia, Ángel; Fernandez-Lafuente, Roberto

2016-06-01

Chemical modification of enzymes and immobilization used to be considered as separate ways to improve enzyme properties. This review shows how the coupled use of both tools may greatly improve the final biocatalyst performance. Chemical modification of a previously immobilized enzyme is far simpler and easier to control than the modification of the free enzyme. Moreover, if protein modification is performed to improve its immobilization (enriching the enzyme in reactive groups), the final features of the immobilized enzyme may be greatly improved. Chemical modification may be directed to improve enzyme stability, but also to improve selectivity, specificity, activity, and even cell penetrability. Coupling of immobilization and chemical modification with site-directed mutagenesis is a powerful instrument to obtain fully controlled modification. Some new ideas such as photoreceptive enzyme modifiers that change their physical properties under UV exposition are discussed. © 2016 The Chemical Society of Japan & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

45 CFR 154.230 - Submission and posting of Final Justifications for unreasonable rate increases.

Code of Federal Regulations, 2011 CFR

2011-10-01

... information available to the public on its Web site for at least three years. (d) CMS will post all Final Justifications on the CMS Web site. This information will remain available to the public on the CMS Web site for... submitted in the Preliminary Justification supporting the rate increase; and (2) Prominently post on its Web...

10 CFR 52.83 - Finality of referenced NRC approvals; partial initial decision on site suitability.

Code of Federal Regulations, 2010 CFR

2010-01-01

....145, and 52.171. (b) While a partial decision on site suitability is in effect under 10 CFR 2.617(b)(2... decision on site suitability. 52.83 Section 52.83 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.83 Finality of referenced NRC...

10 CFR 52.83 - Finality of referenced NRC approvals; partial initial decision on site suitability.

Code of Federal Regulations, 2012 CFR

2012-01-01

....145, and 52.171. (b) While a partial decision on site suitability is in effect under 10 CFR 2.617(b)(2... decision on site suitability. 52.83 Section 52.83 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.83 Finality of referenced NRC...

Transmission of light in deep sea water at the site of the ANTARES neutrino telescope

NASA Astrophysics Data System (ADS)

ANTARES Collaboration; Aguilar, J. A.; Albert, A.; Amram, P.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardellier-Desages, F. E.; Aslanides, E.; Aubert, J.-J.; Azoulay, R.; Bailey, D.; Basa, S.; Battaglieri, M.; Becherini, Y.; Bellotti, R.; Beltramelli, J.; Bertin, V.; Billault, M.; Blaes, R.; Blanc, F.; Bland, R. W.; de Botton, N.; Boulesteix, J.; Bouwhuis, M. C.; Brooks, C. B.; Bradbury, S. M.; Bruijn, R.; Brunner, J.; Bugeon, F.; Burgio, G. F.; Cafagna, F.; Calzas, A.; Caponetto, L.; Carmona, E.; Carr, J.; Cartwright, S. L.; Cecchini, S.; Charvis, P.; Circella, M.; Colnard, C.; Compère, C.; Croquette, J.; Cooper, S.; Coyle, P.; Cuneo, S.; Damy, G.; van Dantzig, R.; Deschamps, A.; de Marzo, C.; Destelle, J.-J.; de Vita, R.; Dinkelspiler, B.; Dispau, G.; Drougou, J.-F.; Druillole, F.; Engelen, J.; Favard, S.; Feinstein, F.; Ferry, S.; Festy, D.; Fopma, J.; Fuda, J.-L.; Gallone, J.-M.; Giacomelli, G.; Girard, N.; Goret, P.; Gournay, J.-F.; Hallewell, G.; Hartmann, B.; Heijboer, A.; Hello, Y.; Hernández-Rey, J. J.; Herrouin, G.; Hößl, J.; Hoffmann, C.; Hubbard, J. R.; Jaquet, M.; de Jong, M.; Jouvenot, F.; Kappes, A.; Karg, T.; Karkar, S.; Karolak, M.; Katz, U.; Keller, P.; Kooijman, P.; Korolkova, E. V.; Kouchner, A.; Kretschmer, W.; Kudryavtsev, V. A.; Lafoux, H.; Lagier, P.; Lamare, P.; Languillat, J.-C.; Laubier, L.; Legou, T.; Le Guen, Y.; Le Provost, H.; Le van Suu, A.; Lo Nigro, L.; Lo Presti, D.; Loucatos, S.; Louis, F.; Lyashuk, V.; Magnier, P.; Marcelin, M.; Margiotta, A.; Maron, C.; Massol, A.; Mazéas, F.; Mazeau, B.; Mazure, A.; McMillan, J. E.; Michel, J.-L.; Millot, C.; Milovanovic, A.; Montanet, F.; Montaruli, T.; Morel, J.-P.; Moscoso, L.; Nezri, E.; Niess, V.; Nooren, G. J.; Ogden, P.; Olivetto, C.; Palanque-Delabrouille, N.; Payre, P.; Petta, C.; Pineau, J.-P.; Poinsignon, J.; Popa, V.; Potheau, R.; Pradier, T.; Racca, C.; Randazzo, N.; Real, D.; van Rens, B. A. P.; Réthoré, F.; Ripani, M.; Roca-Blay, V.; Romeyer, A.; Rollin, J.-F.; Romita, M.; Rose, H. J.; Rostovtsev, A.; Ruppi, M.; Russo, G. V.; Sacquin, Y.; Saouter, S.; Schuller, J.-P.; Schuster, W.; Sokalski, I.; Suvorova, O.; Spooner, N. J. C.; Spurio, M.; Stolarczyk, T.; Stubert, D.; Taiuti, M.; Thompson, L. F.; Tilav, S.; Usik, A.; Valdy, P.; Vallage, B.; Vaudaine, G.; Vernin, P.; Virieux, J.; Vladimirsky, E.; de Vries, G.; de Witt Huberts, P.; de Wolf, E.; Zaborov, D.; Zaccone, H.; Zakharov, V.; Zavatarelli, S.; de Zornoza, J. D.; Zúñiga, J.

2005-02-01

The ANTARES neutrino telescope is a large photomultiplier array designed to detect neutrino-induced upward-going muons by their Cherenkov radiation. Understanding the absorption and scattering of light in the deep Mediterranean is fundamental to optimising the design and performance of the detector. This paper presents measurements of blue and UV light transmission at the ANTARES site taken between 1997 and 2000. The derived values for the scattering length and the angular distribution of particulate scattering were found to be highly correlated, and results are therefore presented in terms of an absorption length λabs and an effective scattering length λscteff. The values for blue (UV) light are found to be λabs ≃ 60(26) m, λscteff≃265(122)m, with significant (˜15%) time variability. Finally, the results of ANTARES simulations showing the effect of these water properties on the anticipated performance of the detector are presented.

Feasibility of remotely manipulated welding in space. A step in the development of novel joining technologies

NASA Technical Reports Server (NTRS)

Masubuchi, K.; Agapakis, J. E.; Debiccari, A.; Vonalt, C.

1983-01-01

In order to establish permanent human presence in space technologies of constructing and repairing space stations and other space structures must be developed. Most construction jobs are performed on earth and the fabricated modules will then be delivered to space by the Space Shuttle. Only limited final assembly jobs, which are primarily mechanical fastening, will be performed on site in space. Such fabrication plans, however, limit the designs of these structures, because each module must fit inside the transport vehicle and must withstand launching stresses which are considerably high. Large-scale utilization of space necessitates more extensive construction work on site. Furthermore, continuous operations of space stations and other structures require maintenance and repairs of structural components as well as of tools and equipment on these space structures. Metal joining technologies, and especially high-quality welding, in space need developing.

Final closure of a low level waste disposal facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Potier, J.M.

1995-12-31

The low-level radioactive waste disposal facility operated by the Agence Nationale pour la Gestion des Dechets Radioactifs near La Hague, France was opened in 1969 and is scheduled for final closure in 1996. The last waste package was received in June 1994. The total volume of disposed waste is approximately 525,000 m{sup 3}. The site closure consists of covering the disposal structures with a multi-layer impervious cap system to prevent rainwater from infiltrating the waste isolation system. A monitoring system has been set up to verify the compliance of infiltration rates with hydraulic performance objectives (less than 10 liters permore » square meter and per year).« less

Fuel conservation evaluation of US Army helicopters. Part 5. Ah-1S flight testing. Final report, 31 July-21 September 1982

DOE Office of Scientific and Technical Information (OSTI.GOV)

Todd, L.L.; Savage, R.T.; Vincent, R.L.

1983-01-01

The United States Army Aviation Engineering Flight Activity conducted level flight performance tests of the AH-1S (Prod) helicopter to provide data to determine the most fuel efficient operating conditions. Hot and cold weather test sites were used to extend the range of the advancing tip Mach number data to supplement existing AH-1S performance data. Preliminary analysis of non-dimensional data identifies the effects of compressibility on performance and shows a power penalty of as much as 6% at a high NR/theta. The power required characteristics determined by these tests can be combined with engine performance to determine the most fuel efficientmore » operating conditions.« less

Further ecological and shoreline stability reconnaissance surveys of Back Island, Behm Canal, Southeast Alaska

DOE Office of Scientific and Technical Information (OSTI.GOV)

Young, J.S.; Strand, J.A.; Ecker, R.M.

1987-09-01

A diver reconnaissance of the intertidal and subtidal zones of Back Island was performed to catalog potentially vulnerable shellfish, other invertebrates, and marine plant resources occurring at three proposed alternate pier sites on the west side of Back Island. Additionally, a limited survey of terrestrial vegetation was conducted in the vicinity of one of the proposed alternate pier sites to describe the littoral community and to list the dominant plant species found there. Finally, a reconnaissance survey of the shoreline of Back Island was conducted to evaluate potential changes in shoreline stability resulting from construction of onshore portions of themore » Southeast Alaska Acoustic Measurement Facility (SEAFAC).« less

Ten-Year Performance of Eastern White Pine - under a Crop Tree Release Regime on an Outwash Site

Treesearch

Kenneth M. Desmarais; William B. Leak; William B. Leak

2005-01-01

A young stand of eastern white pine aged 38-40 years received a crop tree release cutting reducing stocking to 100 tree/ac. This stocking level reflects the number of sterms per acre that would be contained in a well stocked mature stand at final harvest (20-in. quadratic mean stand diameter). The stand then was monitored for growth and value change. Stems that grew...

Public health assessment for Rinchem Company Incorporated (a/k/a Old Rinchem Incorporated) Albuquerque, Bernalillo County, New Mexico, Region 6. CERCLIS Number NMD085267961: Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1999-01-22

Rinchem Company, Inc. once operated a chemical distribution business on a 1/2- to 2/3-acre industrial site at 5001 Edith Boulevard NE in Albuquerque, Bernalillo County, New Mexico. Groundwater within the site is contamined with volatile organic compounds (VOCs), such as trichloroethene. The company that currently occupies this site uses city water. The unlikely migration of VOCs from contaminated subsurface soil into the on-site building was examined and the VOC concentrations of indoor air were found to be well below the concentration of concern. However, precaution is needed if soil excavation is performed at some hot spots identified from soil gasmore » survey. Based on the information reviewed, the Agency for Toxic Substances and Disease Registry (ATSDR) has concluded that the old Rinchem site at 5001 Edith Boulevard NE, Albuquerque, New Mexico, is an indeterminate public health hazard. This conclusion is based on the fluctuating, low levels of VOC in a few on-site monitoring wells in the past decade. There are also no adequate data for evaluating off-site contamination in groundwater.« less

Identification and characterization of conservative organic tracers for use as hydrologic tracers for the Yucca Mountain site characterization study. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stetzenbach, K.; Farnham, I.

1996-06-01

Extensive tracer testing is expected to take place at the C-well complex in the Nevada Test Site as part of the Yucca Mountain Site Characterization Project. The C-well complex consists of one pumping well, C3, and two injection wells, C1 and C2 into which tracer will be introduced. The goal of this research was to provide USGS with numerous tracers to completed these tests. Several classes of fluorinated organic acids have been evaluated. These include numerous isomers of fluorinated benzoic acids, cinnamic acids, and salicylic acids. Also several derivatives of 2-hydroxy nicotinic acid (pyridone) have been tested. The stability ofmore » these compounds was determined using batch and column tests. Ames testing (mutagenicity/carcinogenicity) was conducted on the fluorinated benzoic acids and a literature review of toxicity of the fluorobenzoates and three perfluoro aliphatic acids was prepared. Solubilities were measured and method development work was performed to optimize the detection of these compounds. A Quality Assurance (QA) Program was developed under existing DOE and USGS guidelines. The program includes QA procedures and technical standard operating procedures. A tracer test, using sodium iodide, was performed at the C-well complex. HRC chemists performed analyses on site, to provide real time data for the USGS hydrologists and in the laboratories at UNLV. Over 2,500 analyses were performed. This report provides the results of the laboratory experiments and literature reviews used to evaluate the potential tracers and reports on the results of the iodide C-well tracer test.« less

Remedial action plan and site design for stabilization of the inactive uranium mill tailings sites at Rifle, Colorado. Volume 2, Appendices D and E: Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-02-01

This appendix assesses the present conditions and data gathered about the two inactive uranium mill tailings sites near Rifle, Colorado, and the designated disposal site six miles north of Rifle in the area of Estes Gulch. It consolidates available engineering, radiological, geotechnical, hydrological, meteorological, and other information pertinent to the design of the Remedial Action Plan (RAP). The data characterize conditions at the mill, tailings, and disposal site so that the Remedial Action Contractor (RAC) may complete final designs for the remedial actions.

Effect of the Drilling Technique on Heat Generation During Osteotomy Preparation for Wide-Diameter Implants.

PubMed

El-Kholey, Khalid E; Elkomy, Aamna

2016-12-01

To test the hypothesis that there would be no difference in heat generation by reducing the number of drills during the implant site preparation relative to conventional drilling sequence. A total of 80 implant site preparations with 2 different diameters (5.6 and 6.2 mm) were performed on bovine ribs. Within the same diameter group, half of the preparations were performed by a simplified drilling procedure (pilot drill + final diameter drill) and the other half using the conventional drilling protocol, where multiple drills of increasing diameter were utilized. Heat production by different drilling techniques was evaluated by measuring the bone temperature using K-type thermocouple and a sensitive thermometer before and after each drill. Mean for maximum temperature increase during site preparation of the 5.6- and 6.2-mm implants was 2.20°C, and it was 2.55°C when the site was prepared by the simplified procedure, whereas it was 2.80°C and 2.95°C for the sites prepared by the conventional technique, respectively. No significant difference in temperature increase was found when implants of the 2 chosen diameters were prepared either by the conventional or simplified drilling procedure. The simplified drilling protocol produces similar amount of heat comparable to the conventional technique, which proved the initial hypothesis.

Evoked potentials in final epoch of self-initiated hand movement: A study in patients with depth electrodes.

PubMed

Kukleta, Miloslav; Damborská, Alena; Turak, Baris; Louvel, Jacques

2017-07-01

Comparison between the intended and performed motor action can be expected to occur in the final epoch of a voluntary movement. In search for electrophysiological correlates of this mental process the purpose of the current study was to identify intracerebral sites activated in final epoch of self-paced voluntary movement. Intracerebral EEG was recorded from 235 brain regions of 42 epileptic patients who performed self-paced voluntary movement task. Evoked potentials starting at 0 to 243ms after the peak of averaged, rectified electromyogram were identified in 21 regions of 13 subjects. The mean amplitude value of these late movement potentials (LMP) was 56.4±27.5μV. LMPs were observed in remote regions of mesiotemporal structures, cingulate, frontal, temporal, parietal, and occipital cortices. Closely before the LMP onset, a significant increase of phase synchronization was observed in all EEG record pairs in 9 of 10 examined subjects; p<0.001, Mann-Whitney U test. In conclusion, mesiotemporal structures, cingulate, frontal, temporal, parietal, and occipital cortices seem to represent integral functionally linked parts of network activated in final epoch of self-paced voluntary movement. Activation of this large-scale neuronal network was suggested to reflect a comparison process between the intended and actually performed motor action. Our results contribute to better understanding of neural mechanisms underlying goal-directed behavior crucial for creation of agentive experience. Copyright © 2017 Elsevier B.V. All rights reserved.

Partial Updating of TSCA Inventory DataBase; Production and Site Reports; Final Rule

EPA Pesticide Factsheets

A partial updating of the TSCA inventory database. The final rule requires manufacturers and importers of certain chemical substances included on the TSCA Chemical Substances Inventory to report current data on the production volume, plant site, etc.

Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms.

PubMed

Dove, Katja K; Stieglitz, Benjamin; Duncan, Emily D; Rittinger, Katrin; Klevit, Rachel E

2016-08-01

RING-in-between-RING (RBR) ubiquitin (Ub) ligases are a distinct class of E3s, defined by a RING1 domain that binds E2 Ub-conjugating enzyme and a RING2 domain that contains an active site cysteine similar to HECT-type E3s. Proposed to function as RING/HECT hybrids, details regarding the Ub transfer mechanism used by RBRs have yet to be defined. When paired with RING-type E3s, E2s perform the final step of Ub ligation to a substrate. In contrast, when paired with RBR E3s, E2s must transfer Ub onto the E3 to generate a E3~Ub intermediate. We show that RBRs utilize two strategies to ensure transfer of Ub from the E2 onto the E3 active site. First, RING1 domains of HHARI and RNF144 promote open E2~Ubs. Second, we identify a Ub-binding site on HHARI RING2 important for its recruitment to RING1-bound E2~Ub. Mutations that ablate Ub binding to HHARI RING2 also decrease RBR ligase activity, consistent with RING2 recruitment being a critical step for the RBR Ub transfer mechanism. Finally, we demonstrate that the mechanism defined here is utilized by a variety of RBRs. © 2016 The Authors.

DARC 2.0: Improved Docking and Virtual Screening at Protein Interaction Sites

PubMed Central

Gowthaman, Ragul; Lyskov, Sergey; Karanicolas, John

2015-01-01

Over the past decade, protein-protein interactions have emerged as attractive but challenging targets for therapeutic intervention using small molecules. Due to the relatively flat surfaces that typify protein interaction sites, modern virtual screening tools developed for optimal performance against “traditional” protein targets perform less well when applied instead at protein interaction sites. Previously, we described a docking method specifically catered to the shallow binding modes characteristic of small-molecule inhibitors of protein interaction sites. This method, called DARC (Docking Approach using Ray Casting), operates by comparing the topography of the protein surface when “viewed” from a vantage point inside the protein against the topography of a bound ligand when “viewed” from the same vantage point. Here, we present five key enhancements to DARC. First, we use multiple vantage points to more accurately determine protein-ligand surface complementarity. Second, we describe a new scheme for rapidly determining optimal weights in the DARC scoring function. Third, we incorporate sampling of ligand conformers “on-the-fly” during docking. Fourth, we move beyond simple shape complementarity and introduce a term in the scoring function to capture electrostatic complementarity. Finally, we adjust the control flow in our GPU implementation of DARC to achieve greater speedup of these calculations. At each step of this study, we evaluate the performance of DARC in a “pose recapitulation” experiment: predicting the binding mode of 25 inhibitors each solved in complex with its distinct target protein (a protein interaction site). Whereas the previous version of DARC docked only one of these inhibitors to within 2 Å RMSD of its position in the crystal structure, the newer version achieves this level of accuracy for 12 of the 25 complexes, corresponding to a statistically significant performance improvement (p < 0.001). Collectively then, we find that the five enhancements described here – which together make up DARC 2.0 – lead to dramatically improved speed and performance relative to the original DARC method. PMID:26181386

Tracing Cytoplasmic Ca2+ Ion and Water Access Points in the Ca2+-ATPase

PubMed Central

Musgaard, Maria; Thøgersen, Lea; Schiøtt, Birgit; Tajkhorshid, Emad

2012-01-01

Sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) transports two Ca2+ ions across the membrane of the sarco(endo)plasmic reticulum against the concentration gradient, harvesting the required energy by hydrolyzing one ATP molecule during each transport cycle. Although SERCA is one of the best structurally characterized membrane transporters, it is still largely unknown how the transported Ca2+ ions reach their transmembrane binding sites in SERCA from the cytoplasmic side. Here, we performed extended all-atom molecular dynamics simulations of SERCA. The calculated electrostatic potential of the protein reveals a putative mechanism by which cations may be attracted to and bind to the Ca2+-free state of the transporter. Additional molecular dynamics simulations performed on a Ca2+-bound state of SERCA reveal a water-filled pathway that may be used by the Ca2+ ions to reach their buried binding sites from the cytoplasm. Finally, several residues that are involved in attracting and guiding the cations toward the possible entry channel are identified. The results point to a single Ca2+ entry site close to the kinked part of the first transmembrane helix, in a region loaded with negatively charged residues. From this point, a water pathway outlines a putative Ca2+ translocation pathway toward the transmembrane ion-binding sites. PMID:22339863

Site-Specific Phosphorylation of Ikaros Induced by Low-Dose Ionizing Radiation Regulates Cell Cycle Progression of B Lymphoblast Through CK2 and AKT Activation.

PubMed

Cho, Seong-Jun; Kang, Hana; Kim, Min Young; Lee, Jung Eun; Kim, Sung Jin; Nam, Seon Young; Kim, Ji Young; Kim, Hee Sun; Pyo, Suhkneung; Yang, Kwang Hee

2016-04-01

To determine how low-dose ionizing radiation (LDIR) regulates B lympho-proliferation and its molecular mechanism related with Ikaros, transcription factor. Splenocytes and IM-9 cells were uniformly irradiated with various doses of a (137)Cs γ-source, and cell proliferation was analyzed. To determine the LDIR-specific phosphorylation of Ikaros, immunoprecipitation and Western blot analysis were performed. To investigate the physiologic function of LDIR-mediatied Ikaros phosphorylation, Ikaros mutants at phosphorylation sites were generated, and cell cycle analysis was performed. First, we found that LDIR enhances B lymphoblast proliferation in an Ikaros-dependent manner. Moreover, we found that LDIR elevates the phosphorylation level of Ikaros protein. Interestingly, we showed that CK2 and AKT are involved in LDIR-induced Ikaros phosphorylation and capable of regulating DNA binding activity of Ikaros via specific phosphorylation. Finally, we identified LDIR-specific Ikaros phosphorylation sites at S391/S393 and showed that the Ikaros phosphorylations at these sites control Ikaros's ability to regulate G1/S cell cycle progression. Low-dose ionizing radiation specifically phosphorylates Ikaros protein at Ser 391/393 residues to regulate cell cycle progression in B lymphoblast. Copyright © 2016 Elsevier Inc. All rights reserved.

Evaluation of Dengue-Related Health Information on the Internet

PubMed Central

Rao, Navya R.; Mohapatra, Manaswini; Mishra, Swayamprabha; Joshi, Ashish

2012-01-01

The objective of this study was to examine the quality of dengue-related health information on the Internet. Three raters used the keyword dengue to search the Google, Yahoo!, and Bing search engines during August 2011. The first 20 websites from each search engine were examined for a total of 60 sites. Duplicate, nonfunctional, non-English, and nonoperational websites were excluded from the study, resulting in 36 sites for final analysis. The 16-item DISCERN tool was used to evaluate the quality of dengue-related health information on the Internet. Chi-square analysis and analysis of variance were performed to compare the DISCERN scores. Inter-rater reliability analysis showed significant differences in the level of agreement among the three raters. The 36 unique websites were categorized into .com, .edu, .gov, .org, and other sites. The .com sites had the lowest DISCERN scores. Educating consumers on how to find and recognize valid health information on the Internet may lead to better informed decision making. PMID:22783151

Predicting protein amidation sites by orchestrating amino acid sequence features

NASA Astrophysics Data System (ADS)

Zhao, Shuqiu; Yu, Hua; Gong, Xiujun

2017-08-01

Amidation is the fourth major category of post-translational modifications, which plays an important role in physiological and pathological processes. Identifying amidation sites can help us understanding the amidation and recognizing the original reason of many kinds of diseases. But the traditional experimental methods for predicting amidation sites are often time-consuming and expensive. In this study, we propose a computational method for predicting amidation sites by orchestrating amino acid sequence features. Three kinds of feature extraction methods are used to build a feature vector enabling to capture not only the physicochemical properties but also position related information of the amino acids. An extremely randomized trees algorithm is applied to choose the optimal features to remove redundancy and dependence among components of the feature vector by a supervised fashion. Finally the support vector machine classifier is used to label the amidation sites. When tested on an independent data set, it shows that the proposed method performs better than all the previous ones with the prediction accuracy of 0.962 at the Matthew's correlation coefficient of 0.89 and area under curve of 0.964.

Adaptive Covariation between the Coat and Movement Proteins of Prunus Necrotic Ringspot Virus

PubMed Central

Codoñer, Francisco M.; Fares, Mario A.; Elena, Santiago F.

2006-01-01

The relative functional and/or structural importance of different amino acid sites in a protein can be assessed by evaluating the selective constraints to which they have been subjected during the course of evolution. Here we explore such constraints at the linear and three-dimensional levels for the movement protein (MP) and coat protein (CP) encoded by RNA 3 of prunus necrotic ringspot ilarvirus (PNRSV). By a maximum-parsimony approach, the nucleotide sequences from 46 isolates of PNRSV varying in symptomatology, host tree, and geographic origin have been analyzed and sites under different selective pressures have been identified in both proteins. We have also performed covariation analyses to explore whether changes in certain amino acid sites condition subsequent variation in other sites of the same protein or the other protein. These covariation analyses shed light on which particular amino acids should be involved in the physical and functional interaction between MP and CP. Finally, we discuss these findings in the light of what is already known about the implication of certain sites and domains in structure and protein-protein and RNA-protein interactions. PMID:16731922

Adaptive covariation between the coat and movement proteins of prunus necrotic ringspot virus.

PubMed

Codoñer, Francisco M; Fares, Mario A; Elena, Santiago F

2006-06-01

The relative functional and/or structural importance of different amino acid sites in a protein can be assessed by evaluating the selective constraints to which they have been subjected during the course of evolution. Here we explore such constraints at the linear and three-dimensional levels for the movement protein (MP) and coat protein (CP) encoded by RNA 3 of prunus necrotic ringspot ilarvirus (PNRSV). By a maximum-parsimony approach, the nucleotide sequences from 46 isolates of PNRSV varying in symptomatology, host tree, and geographic origin have been analyzed and sites under different selective pressures have been identified in both proteins. We have also performed covariation analyses to explore whether changes in certain amino acid sites condition subsequent variation in other sites of the same protein or the other protein. These covariation analyses shed light on which particular amino acids should be involved in the physical and functional interaction between MP and CP. Finally, we discuss these findings in the light of what is already known about the implication of certain sites and domains in structure and protein-protein and RNA-protein interactions.

Approaches to consider covers and liners in a low-level waste disposal facility performance assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seitz, Roger; Phifer, Mark; Suttora, Linda

2015-03-17

On-site disposal cells are in use and being considered at several USDOE sites as the final disposition for large amounts of waste associated with cleanup of contaminated areas and facilities. These disposal cells are typically regulated by States and/or the USEPA in addition to having to comply with requirements in DOE Order 435.1, Radioactive Waste Management. The USDOE-EM Office of Site Restoration formed a working group to foster improved communication and sharing of information for personnel associated with these Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) disposal cells and work towards more consistent assumptions, as appropriate, for technical andmore » policy considerations related to performance and risk assessments in support of a Record of Decision and Disposal Authorization Statement. One task completed by the working group addressed approaches for considering the performance of covers and liners/leachate collection systems in the context of a performance assessment (PA). A document has been prepared which provides recommendations for a general approach to address covers and liners/leachate collection systems in a PA and how to integrate assessments with defense-in-depth considerations such as design, operations and waste acceptance criteria to address uncertainties. Specific information and references are provided for details needed to address the evolution of individual components of cover and liner/leachate collection systems. This information is then synthesized into recommendations for best practices for cover and liner system design and examples of approaches to address the performance of covers and liners as part of a performance assessment of the disposal system.« less

Technical support for geopressured-geothermal activities in Louisiana. Final geological report, 1 November 1981-31 October 1982

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pilger, R.H.

1984-06-25

This report contains the component Site-Specific Studies-Geophysics, Diagenesis, Geochemistry. Work for Site-Specific Studies is finished, and the results presented in this report are final. Individual studies have been entered separately into the data base. (ACR)

The Development of a Portable Modular Component Building System for the Armed Forces

DTIC Science & Technology

1985-11-08

environment and provide optimum thermal comfort and energy performance throughout a wide climatic range. Finally, such a system would provide optimum user...I I I I I l i 56. ind thermal comfort . The low humidity of the atmosphere allows temperatures to fal. deeply at night so buildings constructed of hig...site topographies. Extensive support equipment is also required for their transport, erection and sustained thermal comfort for the occupants. Off the

Regulatory mechanisms of eosinopoiesis. Final technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ottolenghi, A.; Bernheim, F.

1979-01-01

Studies were performed with whole-body and partial-body x-irradiation of mice to examine regenerative response of major hematopoietic sites and peripheral pools. Doses from 150 to 600 r were given with various forms of shielding. From consistent results, the author concluded that the shielded marrow was responding to a specific eosinophilic stimulus possibly originating in the irradiated areas with a time course independent of the regenerative pattern of the other nucleated elements of the marrow. (PCS)

Jefferson Proving Ground, South of the Fining Line, Final Remedial Investigation/Feasibility Study, Resource Management Plan

DTIC Science & Technology

1993-01-01

and various DOD sites. I From 1984 to 1987, Mr. Pincock was a Certified Radiation and Chemistry Technician for United Nuclear Industries. He performed...in 1983, Mr. Pincock assisted the senior technical staff in radiation protection as a Junior Health Physics Technician at the Nuclear Support Services...SCOPE OF PROGRAM This plan contains a description of the personnel and procedures for managing the Remedial Investigation/Feasibility Study (RI/FS) at

EEAP lighting survey study at the Red River Army Depot, Texarkana, Texas. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The purpose of the study was to perform a limited site survey of specific buildings at the facility, identify specific Energy Conservation Opportunities (ECOs) that exist, and then evaluate these ECOs for technical and economic feasibility. These ECOs were limited to building interior lighting and it`s effects on the heating, ventilating and air conditioning (HVAC) systems. This survey was conducted with the assistance of many individuals at the facility.

Rational Design of N- S- Fe- Doped Nanoporous Carbon Catalysts from Covalent Triazine Framework for High Efficient ORR.

PubMed

Zhu, Yuanzhi; Chen, Xifan; Liu, Jing; Zhang, Junfeng; Xu, Danyun; Peng, Wenchao; Li, Yang; Zhang, Guoliang; Zhang, Fengbao; Fan, Xiaobin

2018-05-15

Porous organic polymers (POFs) are promising precursors for developing high performance transition metal-nitrogen-carbon (M-N/C) catalysts towards ORR. But the rational design of POFs precursors remain a great challenge, because of the elusive structural association between the sacrificial POFs and the final M-N/C catalysts. Based on covalent triazine frameworks (CTFs), we developed a series of sulfur-doped Fe-N/C catalysts by selecting six different aromatic nitriles as building blocks. A new mixed solvent of molten FeCl3 and S was used for CTF polymerization, which benefit the formation of Fe-Nx site and make the subsequent pyrolysis process more convenient. Comprehensive study on these CTF-derived catalysts shows their ORR activities are not directly dependent on the theoretical N/C ratio of the building block, but closely correlated to the ratios of the nitrile group to benzene ring (Nnitrile/Nbenzene) and geometries of the building blocks. The high ratios of the Nnitrile/Nbenzene are crucial for ORR activity of the final catalysts due to the formation of more N-doped microporous and Fe-Nx sites in pyrolysis possess. The optimized catalyst shows high ORR performances in acid and superior ORR activity to the Pt/C catalysts under alkaline conditions. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Visibility Analysis of Domestic Satellites on Proposed Ground Sites for Optical Surveillance

NASA Astrophysics Data System (ADS)

Kim, Jae-Hyuk; Jo, Jung Hyun; Choi, Jin; Moon, Hong-Kyu; Choi, Young-Jun; Yim, Hong-Suh; Park, Jang-Hyun; Park, Eun-Seo; Park, Jong-Uk

2011-12-01

The objectives of this study are to analyze the satellite visibility at the randomly established ground sites, to determine the five optimal ground sites to perform the optical surveillance and tracking of domestic satellites, and to verify the acquisition of the optical observation time sufficient to maintain the precise ephemeris at optimal ground sites that have been already determined. In order to accomplish these objectives, we analyzed the visibility for sun-synchronous orbit satellites, low earth orbit satellites, middle earth orbit satellites and domestic satellites as well as the continuous visibility along with the fictitious satellite ground track, and calculate the effective visibility. For the analysis, we carried out a series of repetitive process using the satellite tool kit simulation software developed by Analytical Graphics Incorporated. The lighting states of the penumbra and direct sun were set as the key constraints of the optical observation. The minimum of the observation satellite elevation angle was set to be 20 degree, whereas the maximum of the sun elevation angle was set to be -10 degree which is within the range of the nautical twilight. To select the candidates for the optimal optical observation, the entire globe was divided into 84 sectors in a constant interval, the visibility characteristics of the individual sectors were analyzed, and 17 ground sites were arbitrarily selected and analyzed further. Finally, five optimal ground sites (Khurel Togoot Observatory, Assy-Turgen Observatory, Tubitak National Observatory, Bisdee Tier Optical Astronomy Observatory, and South Africa Astronomical Observatory) were determined. The total observation period was decided as one year. To examine the seasonal variation, the simulation was performed for the period of three days or less with respect to spring, summer, fall and winter. In conclusion, we decided the optimal ground sites to perform the optical surveillance and tracking of domestic satellites and verified that optical observ! ation ti me sufficient to maintain the precise ephemeris could be acquired at the determined observatories.

The distributed production system of the SuperB project: description and results

NASA Astrophysics Data System (ADS)

Brown, D.; Corvo, M.; Di Simone, A.; Fella, A.; Luppi, E.; Paoloni, E.; Stroili, R.; Tomassetti, L.

2011-12-01

The SuperB experiment needs large samples of MonteCarlo simulated events in order to finalize the detector design and to estimate the data analysis performances. The requirements are beyond the capabilities of a single computing farm, so a distributed production model capable of exploiting the existing HEP worldwide distributed computing infrastructure is needed. In this paper we describe the set of tools that have been developed to manage the production of the required simulated events. The production of events follows three main phases: distribution of input data files to the remote site Storage Elements (SE); job submission, via SuperB GANGA interface, to all available remote sites; output files transfer to CNAF repository. The job workflow includes procedures for consistency checking, monitoring, data handling and bookkeeping. A replication mechanism allows storing the job output on the local site SE. Results from 2010 official productions are reported.

Installation-restoration program. Phase 2. Confirmation/quantification. Stage 1 for Mather AFB, Sacramento, California. Volume 1. Final report, September 1983-June 1986

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

A Problem Confirmation Study was performed at three sites on Mather AFB identified in the Phase I investigation as requiring further study (the Air command and warning Area, the 7100 Area, the West Ditch) and the Northeast Perimeter. The field investigation was conducted from February 1984 to June 1985 and included installation of 11 monitor wells, collection of groundwater samples from the monitor wells and 15 base production wells, and collection of sediment samples from two locations on the West Ditch. Analytes included oil and grease, TOC, volatile organic compounds (VOA), as well as dimethylnitrosamine, phenols, pesticides, and dissolved metalsmore » at some specific sites. Based on the hydrogeologic complexity of the physical setting and the findings of the sampling and analytical work, follow-on investigations were recommended at all three sites.« less

Validation of EO-1 Hyperion and Advanced Land Imager Using the Radiometric Calibration Test Site at Railroad Valley, Nevada

NASA Technical Reports Server (NTRS)

Czapla-Myers, Jeffrey; Ong, Lawrence; Thome, Kurtis; McCorkel, Joel

2015-01-01

The Earth-Observing One (EO-1) satellite was launched in 2000. Radiometric calibration of Hyperion and the Advanced Land Imager (ALI) has been performed throughout the mission lifetime using various techniques that include ground-based vicarious calibration, pseudo-invariant calibration sites, and also the moon. The EO-1 mission is nearing its useful lifetime, and this work seeks to validate the radiometric calibration of Hyperion and ALI from 2013 until the satellite is decommissioned. Hyperion and ALI have been routinely collecting data at the automated Radiometric Calibration Test Site [RadCaTS/Railroad Valley (RRV)] since launch. In support of this study, the frequency of the acquisitions at RadCaTS has been significantly increased since 2013, which provides an opportunity to analyze the radiometric stability and accuracy during the final stages of the EO-1 mission. The analysis of Hyperion and ALI is performed using a suite of ground instrumentation that measures the atmosphere and surface throughout the day. The final product is an estimate of the top-of-atmosphere (TOA) spectral radiance, which is compared to Hyperion and ALI radiances. The results show that Hyperion agrees with the RadCaTS predictions to within 5% in the visible and near-infrared (VNIR) and to within 10% in the shortwave infrared (SWIR). The 2013-2014 ALI results show agreement to within 6% in the VNIR and 7.5% in the SWIR bands. A cross comparison between ALI and the Operational Land Imager (OLI) using RadCaTS as a transfer source shows agreement of 3%-6% during the period of 2013-2014.

Evaluating Ecological Risk to Invertebrate Receptors from PAHs in Sediments at Hazardous Waste Sites (Final Report)

EPA Science Inventory

EPA's Ecological Risk Assessment Support Center (ERASC) announced the release of the final report, Evaluating Ecological Risk to Invertebrate Receptors from PAHs in Sediments at Hazardous Waste Sites. The report provides an overview of an approach for assessing risk to ...

Effects of a Short Drilling Implant Protocol on Osteotomy Site Temperature and Drill Torque.

PubMed

Mihali, Sorin G; Canjau, Silvana; Cernescu, Anghel; Bortun, Cristina M; Wang, Hom-Lay; Bratu, Emanuel

2018-02-01

To establish a protocol for reducing the drilling sequence during implant site preparation based on temperature and insertion torque. The traditional conventional drilling sequence (used several drills with 0.6-mm increment each time) was compared with the proposed short drilling protocol (only used 2 drills: initial and final drill). One hundred drilling osteotomies were performed in bovine and porcine bones. Sets of 2 osteotomy sites were created in 5 bone densities using 2 types of drilling protocols. Thermographic pictures were captured throughout all drilling procedures and analyzed using ThermaCAM Researcher Professional 2.10. Torque values were determined during drilling by measuring electrical input and drill speed. There were statistically significant differences in bone temperature between the conventional and short drilling protocols during implant site preparation (analysis of variance P = 0.0008). However, there were no significant differences between the 2 types of drilling protocols for both implant diameters. Implant site preparation time was significantly reduced when using the short drilling protocol compared with the conventional drilling protocol (P < 0.001). Within the limitations of the study, the short drilling protocol proposed herein may represent a safe approach for implant site preparation.

Binding-Site Assessment by Virtual Fragment Screening

PubMed Central

Huang, Niu; Jacobson, Matthew P.

2010-01-01

The accurate prediction of protein druggability (propensity to bind high-affinity drug-like small molecules) would greatly benefit the fields of chemical genomics and drug discovery. We have developed a novel approach to quantitatively assess protein druggability by computationally screening a fragment-like compound library. In analogy to NMR-based fragment screening, we dock ∼11000 fragments against a given binding site and compute a computational hit rate based on the fraction of molecules that exceed an empirically chosen score cutoff. We perform a large-scale evaluation of the approach on four datasets, totaling 152 binding sites. We demonstrate that computed hit rates correlate with hit rates measured experimentally in a previously published NMR-based screening method. Secondly, we show that the in silico fragment screening method can be used to distinguish known druggable and non-druggable targets, including both enzymes and protein-protein interaction sites. Finally, we explore the sensitivity of the results to different receptor conformations, including flexible protein-protein interaction sites. Besides its original aim to assess druggability of different protein targets, this method could be used to identifying druggable conformations of flexible binding site for lead discovery, and suggesting strategies for growing or joining initial fragment hits to obtain more potent inhibitors. PMID:20404926

Presence of pro-tobacco messages on the Web.

PubMed

Hong, Traci; Cody, Michael J

2002-01-01

Ignored in the finalized Master Settlement Agreement (National Association of Attorneys General, 1998), the unmonitored, unregulated World Wide Web (Web) can operate as a major vehicle for delivering pro-tobacco messages, images, and products to millions of young consumers. A content analysis of 318 randomly sampled pro-tobacco Web sites revealed that tobacco has a pervasive presence on the Web, especially on e-commerce sites and sites featuring hobbies, recreation, and "fetishes." Products can be ordered online on nearly 50% of the sites, but only 23% of the sites included underage verification. Further, only 11% of these sites contain health warnings. Instead, pro-tobacco sites frequently associate smoking with "glamorous" and "alternative" lifestyles, and with images of young males and young (thin, attractive) females. Finally, many of the Web sites offered interactive site features that are potentially appealing to young Web users. Recommendations for future research and counterstrategies are discussed.

Final report on the Seventh International Comparison of Absolute Gravimeters (ICAG 2005)

USGS Publications Warehouse

Jiang, Z.; Francis, O.; Vitushkin, L.; Palinkas, V.; Germak, A.; Becker, M.; D'Agostino, G.; Amalvict, M.; Bayer, R.; Bilker-Koivula, M.; Desogus, S.; Faller, J.; Falk, R.; Hinderer, J.; Gagnon, C.; Jakob, T.; Kalish, E.; Kostelecky, J.; Lee, C.; Liard, J.; Lokshyn, Y.; Luck, B.; Makinen, J.; Mizushima, S.; Le, Moigne N.; Origlia, C.; Pujol, E.R.; Richard, P.; Robertsson, L.; Ruess, D.; Schmerge, D.; Stus, Y.; Svitlov, S.; Thies, S.; Ullrich, C.; Van Camp, M.; Vitushkin, A.; Ji, W.; Wilmes, H.

2011-01-01

The Bureau International des Poids et Mesures (BIPM), S??vres, France, hosted the 7th International Comparison of Absolute Gravimeters (ICAG) and the associated Relative Gravity Campaign (RGC) from August to September 2005. ICAG 2005 was prepared and performed as a metrological pilot study, which aimed: To determine the gravity comparison reference values; To determine the offsets of the absolute gravimeters; and As a pilot study to accumulate experience for the CIPM Key Comparisons. This document presents a complete and extensive review of the technical protocol and data processing procedures. The 1st ICAG-RGC comparison was held at the BIPM in 1980-1981 and since then meetings have been organized every 4 years. In this paper, we present an overview of how the meeting was organized, the conditions of BIPM gravimetric sites, technical specifications, data processing strategy and an analysis of the final results. This 7th ICAG final report supersedes all previously published reports. Readings were obtained from participating instruments, 19 absolute gravimeters and 15 relative gravimeters. Precise levelling measurements were carried out and all measurements were performed on the BIPM micro-gravity network which was specifically designed for the comparison. ?? 2011 BIPM & IOP Publishing Ltd.

Closure Report for Corrective Action Unit 412: Clean Slate I Plutonium Dispersion (TTR) Tonopah Test Range, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matthews, Patrick

This Closure Report (CR) presents information supporting the clean closure of Corrective Action Unit (CAU) 412: Clean Slate I Plutonium Dispersion (TTR), located on the Tonopah Test Range, Nevada. CAU 412 consists of a release of radionuclides to the surrounding soil from a storage–transportation test conducted on May 25, 1963. Corrective action investigation (CAI) activities were performed in April and May 2015, as set forth in the Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 412: Clean Slate I Plutonium Dispersion (TTR), Tonopah Test Range, Nevada; and in accordance with the Soils Activity Quality Assurance Plan. Themore » purpose of the CAI was to fulfill data needs as defined during the data quality objectives process. The CAU 412 dataset of investigation results was evaluated based on a data quality assessment. This assessment demonstrated the dataset is complete and acceptable for use in fulfilling the data needs identified by the data quality objectives process. This CR provides documentation and justification for the clean closure of CAU 412 under the FFACO without further corrective action. This justification is based on historical knowledge of the site, previous site investigations, implementation of the 1997 interim corrective action, and the results of the CAI. The corrective action of clean closure was confirmed as appropriate for closure of CAU 412 based on achievement of the following closure objectives: Radiological contamination at the site is less than the final action level using the ground troops exposure scenario (i.e., the radiological dose is less than the final action level): Removable alpha contamination is less than the high contamination area criterion: No potential source material is present at the site, and any impacted soil associated with potential source material has been removed so that remaining soil contains contaminants at concentrations less than the final action levels: and There is sufficient information to characterize investigation and remediation waste for disposal.« less

Proposed plan for final remedial action for the groundwater operable unit at the chemical plant area of the Weldon Spring Site, Weldon Spring, Missouri.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2003-08-06

This Proposed Plan (PP) presents the preferred alternative for addressing contaminated groundwater and springs at the Chemical Plant area of the Weldon Spring site, in Weldon Spring, Missouri. The site is located about 30 mi west of St. Louis, in St. Charles County (Figure 1). This proposed action constitutes the final remedial action for the Weldon Spring site. The residual contamination in groundwater and springs at the Chemical Plant area is the only remaining contamination that needs to be addressed for the site. All other contamination has been addressed by previous remedial actions. After this remedial action is implemented, long-termmore » surveillance and maintenance activities will maintain the effectiveness of all remedial actions conducted at the Weldon Spring site, including this final remedial action for groundwater and springs that is being proposed in this plan. DOE complies with the requirements of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) in conducting remedial activities at the site. National Environmental Policy Act (NEPA) values have been incorporated into the CERCLA process; that is, the analysis conducted and presented in the remedial investigation/feasibility study (RI/FS) reports included an evaluation of environmental impacts that is comparable to that performed under NEPA. This PP is required under CERCLA to (1) notify the public and present a brief analysis of the remedial action alternatives, (2) identify and present the rationale for the preferred remedial action alternative identified in the PP, (3) summarize key information from the RI/FS evaluations, including the Baseline Risk Assessment (BRA), and (4) inform the public of its role in the remedy selection process and give the public the opportunity to participate in the process. Remediation activities at the Weldon Spring site have been coordinated with the U.S. Environmental Protection Agency (EPA) and the Missouri Department of Natural Resources (MDNR). The EPA has overall oversight and approval authority, with consultation provided by the MDNR. A range of alternatives was considered in identifying the preferred alternative. The alternatives were developed after careful analysis of geological, environmental, and human health and ecological risk data and an evaluation of the effectiveness, implementability, and cost of the various technologies available for groundwater remediation at the Chemical Plant area. Monitored natural attenuation (MNA) coupled with institutional controls (ICs) and contingency activities has been selected as the preferred alternative.« less

Fiscal Year 2012 Revegetation Assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jenifer Nordstrom

2012-11-01

This report summarizes the Fiscal Year 2012 Revegetation Assessment by Battelle Energy Alliance, LLC. This assessment was conducted to supplement documentation related to the Storm Water Pollution Prevention Plan for Construction Activities and to ensure that disturbed vegetation and soil at various locations are being restored. This report provides the following information for each site being monitored by the Idaho National Laboratory Environmental Support and Services: • Summary of each site • Assessment of vegetation status and site stabilization at each location • Actions and Resolutions for each site. Ten disturbed sites were evaluated for this assessment. Six have achievedmore » final stabilization. The remaining four sites not meeting the criteria for final stabilization will be evaluated again in the next fiscal year.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rowe, M.D.; Pierce, B.L.

This report presents results of tests of different final site selection methods used for siting large-scale facilities such as nuclear power plants. Test data are adapted from a nuclear power plant siting study conducted on Long Island, New York. The purpose of the tests is to determine whether or not different final site selection methods produce different results, and to obtain some understanding of the nature of any differences found. Decision rules and weighting methods are included. Decision rules tested are Weighting Summation, Power Law, Decision Analysis, Goal Programming, and Goal Attainment; weighting methods tested are Categorization, Ranking, Rating Ratiomore » Estimation, Metfessel Allocation, Indifferent Tradeoff, Decision Analysis lottery, and Global Evaluation. Results show that different methods can, indeed, produce different results, but that the probability that they will do so is controlled by the structure of differences among the sites being evaluated. Differences in weights and suitability scores attributable to methods have reduced significance if the alternatives include one or two sites that are superior to all others in many attributes. The more tradeoffs there are among good and bad levels of different attributes at different sites, the more important are the specifics of methods to the final decision. 5 refs., 14 figs., 19 tabs.« less

Molecular Dynamics in Mixed Solvents Reveals Protein-Ligand Interactions, Improves Docking, and Allows Accurate Binding Free Energy Predictions.

PubMed

Arcon, Juan Pablo; Defelipe, Lucas A; Modenutti, Carlos P; López, Elias D; Alvarez-Garcia, Daniel; Barril, Xavier; Turjanski, Adrián G; Martí, Marcelo A

2017-04-24

One of the most important biological processes at the molecular level is the formation of protein-ligand complexes. Therefore, determining their structure and underlying key interactions is of paramount relevance and has direct applications in drug development. Because of its low cost relative to its experimental sibling, molecular dynamics (MD) simulations in the presence of different solvent probes mimicking specific types of interactions have been increasingly used to analyze protein binding sites and reveal protein-ligand interaction hot spots. However, a systematic comparison of different probes and their real predictive power from a quantitative and thermodynamic point of view is still missing. In the present work, we have performed MD simulations of 18 different proteins in pure water as well as water mixtures of ethanol, acetamide, acetonitrile and methylammonium acetate, leading to a total of 5.4 μs simulation time. For each system, we determined the corresponding solvent sites, defined as space regions adjacent to the protein surface where the probability of finding a probe atom is higher than that in the bulk solvent. Finally, we compared the identified solvent sites with 121 different protein-ligand complexes and used them to perform molecular docking and ligand binding free energy estimates. Our results show that combining solely water and ethanol sites allows sampling over 70% of all possible protein-ligand interactions, especially those that coincide with ligand-based pharmacophoric points. Most important, we also show how the solvent sites can be used to significantly improve ligand docking in terms of both accuracy and precision, and that accurate predictions of ligand binding free energies, along with relative ranking of ligand affinity, can be performed.

Sulfur redox reactions on nanostructured highly oriented pyrolytic graphite (HOPG) electrodes: Direct evidence for superior electrocatalytic performance on defect sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Gongwei; Zheng, Dong; Liu, Dan

Fundamental research of sulfur redox reactions on well-defined controlled model electrode surfaces can provide new information to design high-performance lithium-sulfur batteries. In this paper, we study the electrochemical reduction and oxidation of sulfur on the nanostructured HOPG electrodes with pure basal planes, step plans, and pure edge planes. Finally, our results directly indicate that electrochemical reduction and oxidation of sulfur is significantly affected by the carbon surface structure, namely, the electrochemical reversibility of sulfur redox reaction is much better on edge plane, compared with basal plane and step plane.

Sulfur redox reactions on nanostructured highly oriented pyrolytic graphite (HOPG) electrodes: Direct evidence for superior electrocatalytic performance on defect sites

DOE PAGES

Wang, Gongwei; Zheng, Dong; Liu, Dan; ...

2017-04-28

Fundamental research of sulfur redox reactions on well-defined controlled model electrode surfaces can provide new information to design high-performance lithium-sulfur batteries. In this paper, we study the electrochemical reduction and oxidation of sulfur on the nanostructured HOPG electrodes with pure basal planes, step plans, and pure edge planes. Finally, our results directly indicate that electrochemical reduction and oxidation of sulfur is significantly affected by the carbon surface structure, namely, the electrochemical reversibility of sulfur redox reaction is much better on edge plane, compared with basal plane and step plane.

REAL-TIME IN SITU DETECTION OF ORGANIC CONTAMINANTS BY LASER-INDUCED FLUORESCENCE SYSTEM. Final tropical report (Task 1.3).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daniel J. Stepan; James A. Sorensen; Jaroslav Solc

This report summarizes the results of the field demonstration of a laser-induced fluorescence (LIF) method for characterization of brownfields and other contaminated sites. The technology was provided and demonstrated by Dakota Technologies, Inc. (DTI), of Fargo, North Dakota. LIF generates continuous data on the distribution of polycyclic aromatic hydrocarbons (PAHs) within the soil profile. The sensor used to record real-time data is deployed into the soil using a modified truck-mounted Geoprobe percussion soil probing device. The summary of observations described in the following text represents an independent evaluation of the performance, usefulness, and economics of the demonstrated technology for characterizationmore » at PAH-contaminated sites.« less

NREL/University of Delaware Offshore Wind R&D Collaboration: Cooperative Research and Development Final Report, CRADA Number CRD-10-393

DOE Office of Scientific and Technical Information (OSTI.GOV)

Musial, Walt

2015-11-12

Specifically, the work under this CRADA includes, but is not limited to, the development of test procedures for an offshore test site in Delaware waters; testing of installed offshore wind turbines; performance monitoring of those turbines; and a program of research and development on offshore wind turbine blades, components, coatings, foundations, installation and construction of bottom-fixed structures, environmental impacts, policies, and more generally on means to enhance the reliability, facilitate permitting, and reduce costs for offshore wind turbines. This work will be conducted both at NREL's National Wind Technology Center and participant facilities, as well as the established offshore windmore » test sites.« less

Final Hanford Comprehensive Land-Use Plan Environmental Impact Statement, Hanford Site, Richland, Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

N /A

This Final ''Hanford Comprehensive Land-Use Plan Environmental Impact Statement'' (HCP EIS) is being used by the Department of Energy (DOE) and its nine cooperating and consulting agencies to develop a comprehensive land-use plan (CLUP) for the Hanford Site. The DOE will use the Final HCP EIS as a basis for a Record of Decision (ROD) on a CLUP for the Hanford Site. While development of the CLUP will be complete with release of the HCP EIS ROD, full implementation of the CLUP is expected to take at least 50 years. Implementation of the CLUP would begin a more detailed planningmore » process for land-use and facility-use decisions at the Hanford Site. The DOE would use the CLUP to screen proposals. Eventually, management of Hanford Site areas would move toward the CLUP land-use goals. This CLUP process could take more than 50 years to fully achieve the land-use goals.« less

Pretest information for a test to validate plume simulation procedures (FA-17)

NASA Technical Reports Server (NTRS)

Hair, L. M.

1978-01-01

The results of an effort to plan a final verification wind tunnel test to validate the recommended correlation parameters and application techniques were presented. The test planning effort was complete except for test site finalization and the associated coordination. Two suitable test sites were identified. Desired test conditions were shown. Subsequent sections of this report present the selected model and test site, instrumentation of this model, planned test operations, and some concluding remarks.

Comparative Analysis of Normalised Difference Spectral Indices Derived from MODIS for Detecting Surface Water in Flooded Rice Cropping Systems

PubMed Central

Boschetti, Mirco; Nutini, Francesco; Manfron, Giacinto; Brivio, Pietro Alessandro; Nelson, Andrew

2014-01-01

Identifying managed flooding in paddy fields is commonly used in remote sensing to detect rice. Such flooding, followed by rapid vegetation growth, is a reliable indicator to discriminate rice. Spectral indices (SIs) are often used to perform this task. However, little work has been done on determining which spectral combination in the form of Normalised Difference Spectral Indices (NDSIs) is most appropriate for surface water detection or which thresholds are most robust to separate water from other surfaces in operational contexts. To address this, we conducted analyses on satellite and field spectral data from an agronomic experiment as well as on real farming situations with different soil and plant conditions. Firstly, we review and select NDSIs proposed in the literature, including a new combination of visible and shortwave infrared bands. Secondly, we analyse spectroradiometric field data and satellite data to evaluate mixed pixel effects. Thirdly, we analyse MODIS data and Landsat data at four sites in Europe and Asia to assess NDSI performance in real-world conditions. Finally, we test the performance of the NDSIs on MODIS temporal profiles in the four sites. We also compared the NDSIs against a combined index previously used for agronomic flood detection. Analyses suggest that NDSIs using MODIS bands 4 and 7, 1 and 7, 4 and 6 or 1 and 6 perform best. A common threshold for each NDSI across all sites was more appropriate than locally adaptive thresholds. In general, NDSIs that use band 7 have a negligible increase in Commission Error over those that use band 6 but are more sensitive to water presence in mixed land cover conditions typical of moderate spatial resolution analyses. The best performing NDSI is comparable to the combined index but with less variability in performance across sites, suggesting a more succinct and robust flood detection method. PMID:24586381

Cleanups In My Community (CIMC) - Superfund National Priority List (NPL) Sites, National Layer

EPA Pesticide Factsheets

This data layer provides access to Superfund National Priority List Sites as part of the CIMC web service. Superfund is a program administered by the EPA to locate, investigate, and clean up worst hazardous waste sites throughout the United States. EPA administers the Superfund program in cooperation with individual states and tribal governments. These sites include abandoned warehouses, manufacturing facilities, processing plants, and landfills - the key word here being abandoned.Only NPL sites have been included in Cleanups in My Community thus far. EPA maintains the NPL, which identifies for the States and the public those sites or other releases that appear to warrant remedial (long term) actions. These NPL sites fall into the following categories:Proposed: Sites may be proposed for the NPL and then may be placed on the NPL as final or be removed from the Proposed NPL.Final: Those sites placed on the NPL are called final, and for these sites, a cleanup remedy is selected and implemented. However, it may be several years after construction of the remedy is completed before the hazardous substances are completely cleaned up or controlled in place.Deleted: After the clean up process is complete, and appropriate reviews confirm the area is cleaned up or the hazards are controlled, sites can be deleted from the NPL.For more information on the data provided through this web service, please see the processing steps below, and see more information here: https://www.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cho, Seong-Jun; Kang, Hana; Kim, Min Young

Purpose: To determine how low-dose ionizing radiation (LDIR) regulates B lympho-proliferation and its molecular mechanism related with Ikaros, transcription factor. Methods and Materials: Splenocytes and IM-9 cells were uniformly irradiated with various doses of a {sup 137}Cs γ-source, and cell proliferation was analyzed. To determine the LDIR-specific phosphorylation of Ikaros, immunoprecipitation and Western blot analysis were performed. To investigate the physiologic function of LDIR-mediatied Ikaros phosphorylation, Ikaros mutants at phosphorylation sites were generated, and cell cycle analysis was performed. Results: First, we found that LDIR enhances B lymphoblast proliferation in an Ikaros-dependent manner. Moreover, we found that LDIR elevates the phosphorylationmore » level of Ikaros protein. Interestingly, we showed that CK2 and AKT are involved in LDIR-induced Ikaros phosphorylation and capable of regulating DNA binding activity of Ikaros via specific phosphorylation. Finally, we identified LDIR-specific Ikaros phosphorylation sites at S391/S393 and showed that the Ikaros phosphorylations at these sites control Ikaros's ability to regulate G1/S cell cycle progression. Conclusion: Low-dose ionizing radiation specifically phosphorylates Ikaros protein at Ser 391/393 residues to regulate cell cycle progression in B lymphoblast.« less

Installation-Restoration Program. Phase 2. Confirmation/quantification. Stage 1. Problem confirmation study: Otis Air National Guard Base, Massachusetts, Air National Guard Support Center, Andrews Air Force Base, Maryland. Final technical report, November 1983-July 1985

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kraybill, R.L.; Smart, G.R.; Bopp, F.

1985-09-04

A Problem Confirmation Study was performed at seven sites on Otis Air National Guard Base: the Current and Former Training Areas, the Base Landfill, the Nondestructive Inspection Laboratory, the Fuel Test Dump Site, the Railyard Fuel Pumping Station, and the Petrol Fuel Storage Area. The field investigation was conducted in two stages, in November 1983 through January 1984, and in October through December 1984. Resampling was performed at selected locations in April and July 1985. A total of 11 monitor wells were installed and sampled and test-pit investigations were conducted at six sites. In addition, the contents of a sumpmore » tank, and two header pipes for fuel-transmission lines were sampled. Analytes included TOC, TOX, cyanide, phenols, Safe Drinking Water metals, pesticides and herbicides, and in the second round, priority-pollutant volatile organic compounds and a GC fingerprint scan for fuel products. On the basis of the field-work findings, it is concluded that, to date, water-quality impacts on ground water from past activities have been minimal.« less

OBSERVATIONAL STUDY OF FINAL CLEANING AND AHERA CLEARANCE SAMPLING AT ASBESTOS-ABATEMENT SITES IN NEW JERSEY

EPA Science Inventory

A study was conducted during the summer of 1988 to document final cleaning procedures and evaluate Asbestos Hazard Emergency Response Act (AHERA) clearance air sampling practices used at 20 asbestos-abatement sites in New Jersey. Each abatement took place in a school building and...

Modelling macroseismic observations for historical earthquakes: the cases of the M = 7.0, 1954 Sofades and M = 6.8, 1957 Velestino events (central Greece)

NASA Astrophysics Data System (ADS)

Papazachos, Giannis; Papazachos, Costas; Skarlatoudis, Andreas; Kkallas, Harris; Lekkas, Efthimios

2016-01-01

We attempt to model the spatial distribution of the strong ground motion for the large M = 7.0, 1954 Sofades and M = 6.8, 1957 Velestino events (southern Thessaly basin, central Greece), using the macroseismic intensities ( I M M up to 9+) observed within the broader Thessaly area. For this reason, we employ a modified stochastic method realised by the EXSIM algorithm for extended sources, in order to reproduce the damage distribution of these earthquakes, in an attempt to combine existing earthquake information and appropriate scaling relations with surface geology and to investigate the efficiency of the available macroseismic data. For site-effects assessment, we use a new digital geological map of the broader Thessaly basin, where geological formations are grouped by age and mapped on appropriate NEHRP soil classes. Using the previous approach, we estimate synthetic time series for different rupture scenarios and employ various calibrating relations between PGA/PGV and macroseismic intensity, allowing the generation of synthetic (stochastic) isoseismals. Also, different site amplification factors proposed for the broader Aegean area, according to local geology, are tested. Finally, we also perform a sensitivity analysis of the fault location, taking into account the available neotectonic data for the broader southern Thessaly fault zone. The finally determined fault locations are different than previously proposed, in agreement with the available neotectonic information. The observed macroseismic intensities are in good agreement with the ones derived from the synthetic waveforms, verifying both the usefulness of the approach, as well as of the macroseismic data used. Finally, site-effects show clear correlation with the geological classification employed, with constant amplification factors for each soil class generally providing better results than generic transfer functions.

10 CFR 960.3-2-2-5 - Formal site nomination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final... determines suitable for site characterization for the selection of a repository site, and, in so doing, he...

Distally based sural neuro-fasciocutaneous perforator flap for foot and ankle reconstruction: Surgical modifications for flap pedicle and donor site closure without skin graft.

PubMed

Chi, Zhenglin; Chen, Yiheng; Chu, Tinggang; Gao, Weiyang; Li, Zhijie; Yan, Hede; Song, Yonghuan

2018-02-01

The conventional procedure of the sural neuro-fasciocutaneous flap enables the supply of blood and venous drainage by increasing the width of the adipofascial tissue and preserving tiny venous return routes. Moreover, skin graft is a common method for donor site closure, which may lead to some complications and influence the aesthetic appearance. We report modifications for a distally based sural neuro-fasciocutaneous perforator flap and a relaying flap for donor site closure without skin graft. Twelve patients undergoing the modified flap for foot and ankle reconstruction were included in this study between 2014 and 2016. A peroneal-based perforator, a superficial vein, and the vascular axis of the sural nerve were included in the pedicle. A Z-shape skin incision was performed to explore the perforator vessels and a relaying island perforator flap was used to close the donor site. All flaps survived completely without necrosis. The area of the flaps ranged from 16 × 8 cm to 30 × 15 cm. The diameter width of the pedicle ranged from 1.0 to 2.0 cm. A relaying perforator island flap was used in 10 cases for donor site closure and no skin graft was performed. There were no serious donor site complications. All patients were satisfied with the aesthetic outcome postoperatively at the final follow-up. The distally based sural neuro-fasciocutaneous perforator flap is considered a reliable method for foot and ankle reconstruction. The modification for flap pedicle and donor site closure method without skin graft should be recommended. Copyright © 2017. Published by Elsevier Ltd.

Searching for transcription factor binding sites in vector spaces

PubMed Central

2012-01-01

Background Computational approaches to transcription factor binding site identification have been actively researched in the past decade. Learning from known binding sites, new binding sites of a transcription factor in unannotated sequences can be identified. A number of search methods have been introduced over the years. However, one can rarely find one single method that performs the best on all the transcription factors. Instead, to identify the best method for a particular transcription factor, one usually has to compare a handful of methods. Hence, it is highly desirable for a method to perform automatic optimization for individual transcription factors. Results We proposed to search for transcription factor binding sites in vector spaces. This framework allows us to identify the best method for each individual transcription factor. We further introduced two novel methods, the negative-to-positive vector (NPV) and optimal discriminating vector (ODV) methods, to construct query vectors to search for binding sites in vector spaces. Extensive cross-validation experiments showed that the proposed methods significantly outperformed the ungapped likelihood under positional background method, a state-of-the-art method, and the widely-used position-specific scoring matrix method. We further demonstrated that motif subtypes of a TF can be readily identified in this framework and two variants called the k NPV and k ODV methods benefited significantly from motif subtype identification. Finally, independent validation on ChIP-seq data showed that the ODV and NPV methods significantly outperformed the other compared methods. Conclusions We conclude that the proposed framework is highly flexible. It enables the two novel methods to automatically identify a TF-specific subspace to search for binding sites. Implementations are available as source code at: http://biogrid.engr.uconn.edu/tfbs_search/. PMID:23244338

Site Selection for the Disposal of LLW in Taiwan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chuang, W.S.; Chi, L.M.; Tien, N.C.

2006-07-01

This paper presents the implementation status of the low-level radioactive waste (LLW) disposal program in Taiwan, including the disposal facility regulations, status of waste management, final disposal program, licensing procedures, waste acceptance criteria, site selection criteria and processes and preliminary disposal concepts. The first phase of site selection for low-level radioactive waste final disposal in Taiwan was implemented between 1992 and 2002. The site selection process adopted a Geographic Information System (GIS), Hierarchical Analysis System, Expert Evaluation System, and site reconnaissance. An incentive program for voluntary sites was also initiated. After a series of evaluations and discussion of 30 potentialmore » candidate sites, including 8 recommended sites, 5 qualified voluntary townships, and several remote uninhabited small islets, Hsiao-chiou islet was selected as the first priority candidate site in February 1998. The geological investigation work in Hsiao-chiou was conducted from March 1999 through October 2000. An Environmental Impact Statement Report (EIS) and the Investment Feasibility Study Report (IFS) were submitted to the Environmental Protection Agency (EPA) in November 2000 and to the Ministry of Economic Affairs (MOEA) in June 2001, respectively. Unfortunately, the site investigation was discontinued in 2002 due to political and public acceptance consideration. After years of planning, the second phase of the site selection process was launched in August 2004 and will be conducted through 2008. It is planned that a repository will be constructed in early 2009 and start to operate in 2014. The site selection process for the second phase is based on the earlier work and four potential candidate sites were selected for evaluation until 2005. A near surface disposal concept is proposed for a site located in the Taiwan strait, and cavern disposal concepts are proposed for three other sites located on the main island. This paper presents the implementation status of the LLW disposal program in Taiwan, including the disposal facility regulations, status of waste management, final disposal program, licensing procedures, waste acceptance criteria, site selection criteria and processes, and preliminary disposal concepts 'NIMBY' (Not in my backyard) is a critical problem for implementation of the final disposal project. Resistance from local communities has been continuously received during site characterization. To overcome this, an incentive program to encourage community acceptance has been approved by the Government. Programs for community promotion are being proposed and negotiations are also underway. (authors)« less

Neurology Falls. Patient Falls Risk Assessment, Neurology Clinic, Johns Hopkins Hospital, Baltimore, MD

DTIC Science & Technology

2009-07-06

currently valid ()MB control number. PLEASE DO NOT RETURN YOf IR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 21 JUL 2008 2. REPORT TYPE Final...Hospital, Baltimore, MD 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) LT John M Gardner, MSC, USN 5d. PROJECT...NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) Johns Hopkins Hospital, Baltimore, MD Residency Site

STS-133 crew visit

NASA Image and Video Library

2011-04-20

Stennis Space Center Deputy Director Rick Gilbrech (far right) welcomes members of the STS-133 shuttle mission crew during an April 20 visit. The mission was the final flight for the space shuttle Discovery, which now becomes the first of the three-orbiter fleet to be retired. During the visit to Stennis, Mission Commander Steven Lindsey ( l to r), Pilot Eric Boe and mission specialists Alvin Drew, Steven Bowen, Michael Barratt and Nicole Stott recapped their historic flight and thanked site employees for providing main engines that performed 'as advertised.'

Phase II Testing at a Prehistoric Site (32BA418) at Lake Ashtabula (Sheyenne River) Barnes County, North Dakota.

DTIC Science & Technology

1984-01-01

Subtitle) PHASE II TESTING AT 32BA3, S. TYPE OF REPORT & PERIOD COVERED BARNES COUNTY, NORTH DAKOTA. Final 6. PERFORMING ORG. REPORT NUMBER 7 . AUTHOR(a...3 4. Countour map of 32BA418 showing locations of auger test units, 1 m2 test units, cutbank profile (A - A’) and grid system ......... 7 5...Physiographic subdivisions, North Dakota ....... ............. 9 6. Vegetation zones, North Dakota ...... ................... .11 7 . Great Plains

Mechanism of Intramembrane Cleavage of Alcadeins by γ-Secretase

PubMed Central

Piao, Yi; Kimura, Ayano; Urano, Satomi; Saito, Yuhki; Taru, Hidenori; Yamamoto, Tohru; Hata, Saori; Suzuki, Toshiharu

2013-01-01

Background Alcadein proteins (Alcs; Alcα, Alcβand Alcγ) are predominantly expressed in neurons, as is Alzheimer's β-amyloid (Aβ) precursor protein (APP). Both Alcs and APP are cleaved by primary α- or β-secretase to generate membrane-associated C-terminal fragments (CTFs). Alc CTFs are further cleaved by γ-secretase to secrete p3-Alc peptide along with the release of intracellular domain fragment (Alc ICD) from the membrane. In the case of APP, APP CTFβ is initially cleaved at the ε-site to release the intracellular domain fragment (AICD) and consequently the γ-site is determined, by which Aβ generates. The initial ε-site is thought to define the final γ-site position, which determines whether Aβ40/43 or Aβ42 is generated. However, initial intracellular ε-cleavage sites of Alc CTF to generate Alc ICD and the molecular mechanism that final γ-site position is determined remains unclear in Alcs. Methodology Using HEK293 cells expressing Alcs plus presenilin 1 (PS1, a catalytic unit of γ-secretase) and the membrane fractions of these cells, the generation of p3-Alc possessing C-terminal γ-cleavage site and Alc ICD possessing N-terminal ε-cleavage site were analysed with MALDI-TOF/MS. We determined the initial ε-site position of all Alcα, Alcβ and Alcγ, and analyzed the relationship between the initially determined ε-site position and the final γ-cleavage position. Conclusions The initial ε-site position does not always determine the final γ-cleavage position in Alcs, which differed from APP. No additional γ-cleavage sites are generated from artificial/non-physiological positions of ε-cleavage for Alcs, while the artificial ε-cleavage positions can influence in selection of physiological γ-site positions. Because alteration of γ-secretase activity is thought to be a pathogenesis of sporadic Alzheimer's disease, Alcs are useful and sensitive substrate to detect the altered cleavage of substrates by γ-secretase, which may be induced by malfunction of γ-secretase itself or changes of membrane environment for enzymatic reaction. PMID:23658629

Optimal siting of solid waste-to-value-added facilities through a GIS-based assessment.

PubMed

Khan, Md Mohib-Ul-Haque; Vaezi, Mahdi; Kumar, Amit

2018-01-01

Siting a solid waste conversion facility requires an assessment of solid waste availability as well as ensuring compliance with environmental, social, and economic factors. The main idea behind this study was to develop a methodology to locate suitable locations for waste conversion facilities considering waste availability as well as environmental and social constraints. A geographic information system (GIS) spatial analysis was used to identify the most suitable areas and to screen out unsuitable lands. The analytic hierarchy process (AHP) was used for a multi-criteria evaluation of relative preferences of different environmental and social factors. A case study was conducted for Alberta, a western province in Canada, by performing a province-wide waste availability assessment. The total available waste considered in this study was 4,077,514tonnes/year for 19 census divisions collected from 79 landfills. Finally, a location-allocation analysis was performed to determine suitable locations for 10 waste conversion facilities across the province. Copyright © 2017 Elsevier B.V. All rights reserved.

The human embryonic stem cell proteome revealed by multidimensional fractionation followed by tandem mass spectrometry

PubMed Central

Zhao, Peng; Schulz, Thomas C.; Sherrer, Eric S.; Weatherly, D. Brent; Robins, Allan J.; Wells, Lance

2015-01-01

Human embryonic stem cells (hESCs) have received considerable attention due to their therapeutic potential and usefulness in understanding early development and cell fate commitment. In order to appreciate the unique properties of these pluripotent, self-renewing cells, we have performed an in-depth multidimensional fractionation followed by LC-MS/MS analysis of the hESCs harvested from defined media to elucidate expressed, phosphorylated, O-linked β-N-acetylglucosamine (O-GlcNAc) modified, and secreted proteins. From the triplicate analysis, we were able to assign more than 3000 proteins with less than 1% false-discovery rate. This analysis also allowed us to identify nearly 500 phosphorylation sites and 68 sites of O-GlcNAc modification with the same high confidence. Investigation of the phosphorylation sites allowed us to deduce the set of kinases that are likely active in these cells. We also identified more than 100 secreted proteins of hESCs that likely play a role in extracellular matrix formation and remodeling, as well as autocrine signaling for self-renewal and maintenance of the undifferentiated state. Finally, by performing in-depth analysis in triplicate, spectral counts were obtained for these proteins and posttranslationally modified peptides, which will allow us to perform relative quantitative analysis between these cells and any derived cell type in the future. PMID:25367160

Periodontist-Dental Hygienist Collaboration in Periodontal Care for Chronic Periodontitis: An 11-year Case Report.

PubMed

Tomita, Sachiyo; Uekusa, Tomomi; Hosono, Meiko; Kigure, Takashi; Sugito, Hiroki; Saito, Atsushi

2016-01-01

We report a case of severe chronic periodontitis treated and longitudinally maintained by a periodontist and dental hygienists. The patient was a 45-year-old woman who presented with the chief complaint of gingival bleeding and tooth mobility. An initial examination revealed generalized gingival inflammation and subgingival calculus in the premolar and molar regions. Premature contact was observed in #14 and 45. Clinical examination revealed 42% of sites with a probing depth (PD) of ≥4 mm and 44% of sites with bleeding on probing. Radiographic examination revealed vertical bone resorption in #35, 36, and 45, and horizontal bone resorption in other regions. Based on a clinical diagnosis of severe chronic periodontitis, initial periodontal therapy consisting of plaque control, scaling and root planing, and removal of an ill-fitting prosthesis was performed. Following suppression of inflammation, occlusal adjustment of premature contact sites was performed. Open flap debridement was performed for teeth with a PD of ≥5 mm. After confirming the stability of the periodontal tissue, final prostheses were placed on #16, 35-37, and 46. Following re-evaluation, the patient was placed on supportive periodontal therapy. It has been 11 years since the patient's first visit, and the periodontal conditions have remained stable. Meticulous periodontal care maintained over a number of years by a periodontist and dental hygienist have yielded a clinically favorable outcome.

Remedial Action Plan and site design for stabilization of the inactive uranium mill tailings site at Durango, Colorado: Attachment 5, Dewatering report. Revised final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-12-01

This report provides an update on dewatering activities at the Durango disposal embankment and presents recommendations for the work required to complete the closure of the cell in 1990 (Section 2). In October 1989, test pit investigations were performed and a toe trench was excavated at the eastern slope of the disposal embankment. A description and results of the test pit investigations along with the implications . of the results relative to the over . all dewatering effort are discussed in Sections 3 through 5. Installation and performance of the 17-well dewatering system were previously described in` the ``StatusReport onmore » Dewatering of Disposal Embankment`` issued in September, 1989. Additional studies are still on-going and are described in Section 6. Laboratory analysis continues on samples taken from the test pits. TAC`s characterization of the hydrogeological conditions at the Durango site is also proceeding. Results of these studies will be presented in subsequent reports. Appendices A and B present construction details of the well point system, toe trench and holding pond. Appendix C summarizes the performance-of the 17 pumping wells prior to winter shutdown and provides information on pumping rates, drawdowns, and disposition of the wells. Appendix D outlines the chronology of the dewatering effort to date.« less

Accuracy assessment/validation methodology and results of 2010–11 land-cover/land-use data for Pools 13, 26, La Grange, and Open River South, Upper Mississippi River System

USGS Publications Warehouse

Jakusz, J.W.; Dieck, J.J.; Langrehr, H.A.; Ruhser, J.J.; Lubinski, S.J.

2016-01-11

Similar to an AA, validation involves generating random points based on the total area for each map class. However, instead of collecting field data, two or three individuals not involved with the photo-interpretative mapping separately review each of the points onscreen and record a best-fit vegetation type(s) for each site. Once the individual analyses are complete, results are joined together and a comparative analysis is performed. The objective of this initial analysis is to identify areas where the validation results were in agreement (matches) and areas where validation results were in disagreement (mismatches). The two or three individuals then perform an analysis, looking at each mismatched site, and agree upon a final validation class. (If two vegetation types at a specific site appear to be equally prevalent, the validation team is permitted to assign the site two best-fit vegetation types.) Following the validation team’s comparative analysis of vegetation assignments, the data are entered into a database and compared to the mappers’ vegetation assignments. Agreements and disagreements between the map and validation classes are identified, and a contingency table is produced. This document presents the AA processes/results for Pools 13 and La Grange, as well as the validation process/results for Pools 13 and 26 and Open River South.

Effects of particulate air pollution on the respiratory health of subjects who live in three areas in Kanpur, India.

PubMed

Sharma, Mukesh; Kumar, V Narendra; Katiyar, Subodh K; Sharma, Richa; Shukla, Bhanu P; Sengupta, Babu

2004-07-01

In this study, the authors assessed the relationship between daily changes in respiratory health and particulate levels with diameters of (a) less than 10 microm (PM10) and (b) less than 2.5 microm (PM2.5) in Kanpur, India. The subjects (N = 91) were recruited from 3 areas in Kanpur: (1) Indian Institute of Technology (Kanpur), which was a relatively clean area; (b) Vikas Nagar, a typical commercial area; and (c) finally, the residential area of Juhilal Colony. All subjects resided near to air quality monitoring sites. Air quality and peak expiratory flow rate samplings were conducted for 39 d. Once during the sampling period, lung-function tests (i.e., forced expiratory volume in 1 s, forced vital capacity) were performed on each subject. Subjects who resided at the clean site performed at predicted (i.e., acceptable) values more often than did subjects who lived at the remaining 2 sites. Subjects who lived at all 3 sites demonstrated a substantial average deficit in baseline forced vital capacity and forced expiratory volume in 1 s values. The authors used a statistical model to estimate that an increase of 100 microg/m3 of the pollutant PM10 could reduce the mean peak expiratory flow rate of an individual by approximately 3.2 l/min.

Fish-Friendly Hydropower Turbine Development & Deployment: Alden Turbine Preliminary Engineering and Model Testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Foust, J.; Hecker, G.; Li, S.

2011-10-01

The Alden turbine was developed through the U.S. Department of Energy's (DOE's) former Advanced Hydro Turbine Systems Program (1994-2006) and, more recently, through the Electric Power Research Institute (EPRI) and the DOE's Wind & Water Power Program. The primary goal of the engineering study described here was to provide a commercially competitive turbine design that would yield fish passage survival rates comparable to or better than the survival rates of bypassing or spilling flow. Although the turbine design was performed for site conditions corresponding to 92 ft (28 m) net head and a discharge of 1500 cfs (42.5 cms), themore » design can be modified for additional sites with differing operating conditions. During the turbine development, design modifications were identified for the spiral case, distributor (stay vanes and wicket gates), runner, and draft tube to improve turbine performance while maintaining features for high fish passage survival. Computational results for pressure change rates and shear within the runner passage were similar in the original and final turbine geometries, while predicted minimum pressures were higher for the final turbine. The final turbine geometry and resulting flow environments are expected to further enhance the fish passage characteristics of the turbine. Computational results for the final design were shown to improve turbine efficiencies by over 6% at the selected operating condition when compared to the original concept. Prior to the release of the hydraulic components for model fabrication, finite element analysis calculations were conducted for the stay vanes, wicket gates, and runner to verify that structural design criteria for stress and deflections were met. A physical model of the turbine was manufactured and tested with data collected for power and efficiency, cavitation limits, runaway speed, axial and radial thrust, pressure pulsations, and wicket gate torque. All parameters were observed to fall within ranges expected for conventional radial flow machines. Based on these measurements, the expected efficiency peak for prototype application is 93.64%. These data were used in the final sizing of the supporting mechanical and balance of plant equipment. The preliminary equipment cost for the design specification is $1450/kW with a total supply schedule of 28 months. This equipment supply includes turbine, generator, unit controls, limited balance of plant equipment, field installation, and commissioning. Based on the selected head and flow design conditions, fish passage survival through the final turbine is estimated to be approximately 98% for 7.9-inch (200-mm) fish, and the predicted survival reaches 100% for fish 3.9 inches (100 mm) and less in length. Note that fish up to 7.9- inches (200 mm) in length make up more than 90% of fish entrained at hydro projects in the United States. Completion of these efforts provides a mechanical and electrical design that can be readily adapted to site-specific conditions with additional engineering development comparable to costs associated with conventional turbine designs.« less

Seismic site coefficients and acceleration design response spectra based on conditions in South Carolina : final report.

DOT National Transportation Integrated Search

2014-11-15

The simplified procedure in design codes for determining earthquake response spectra involves : estimating site coefficients to adjust available rock accelerations to site accelerations. Several : investigators have noted concerns with the site coeff...

Semantic Data And Visualization Techniques Applied To Geologic Field Mapping

NASA Astrophysics Data System (ADS)

Houser, P. I. Q.; Royo-Leon, M.; Munoz, R.; Estrada, E.; Villanueva-Rosales, N.; Pennington, D. D.

2015-12-01

Geologic field mapping involves the use of technology before, during, and after visiting a site. Geologists utilize hardware such as Global Positioning Systems (GPS) connected to mobile computing platforms such as tablets that include software such as ESRI's ArcPad and other software to produce maps and figures for a final analysis and report. Hand written field notes contain important information and drawings or sketches of specific areas within the field study. Our goal is to collect and geo-tag final and raw field data into a cyber-infrastructure environment with an ontology that allows for large data processing, visualization, sharing, and searching, aiding in connecting field research with prior research in the same area and/or aid with experiment replication. Online searches of a specific field area return results such as weather data from NOAA and QuakeML seismic data from USGS. These results that can then be saved to a field mobile device and searched while in the field where there is no Internet connection. To accomplish this we created the GeoField ontology service using the Web Ontology Language (OWL) and Protégé software. Advanced queries on the dataset can be made using reasoning capabilities can be supported that go beyond a standard database service. These improvements include the automated discovery of data relevant to a specific field site and visualization techniques aimed at enhancing analysis and collaboration while in the field by draping data over mobile views of the site using augmented reality. A case study is being performed at University of Texas at El Paso's Indio Mountains Research Station located near Van Horn, Texas, an active multi-disciplinary field study site. The user can interactively move the camera around the study site and view their data digitally. Geologist's can check their data against the site in real-time and improve collaboration with another person as both parties have the same interactive view of the data.

A GIS-BASED MULTI-CRITERIA EVALUATION SYSTEM FOR SELECTION OF LANDFILL SITES: a case study from Abu Dhabi, United Arab Emirates

NASA Astrophysics Data System (ADS)

Issa, S. M.; Shehhi, B. Al

2012-07-01

Landfill sites receive 92% of total annual solid waste produced by municipalities in the emirate of Abu Dhabi. In this study, candidate sites for an appropriate landfill location for the Abu Dhabi municipal area are determined by integrating geographic information systems (GIS) and multi-criteria evaluation (MCE) analysis. To identify appropriate landfill sites, eight input map layers including proximity to urban areas, proximity to wells and water table depth, geology and topography, proximity to touristic and archeological sites, distance from roads network, distance from drainage networks, and land slope are used in constraint mapping. A final map was generated which identified potential areas showing suitability for the location of the landfill site. Results revealed that 30% of the study area was identified as highly suitable, 25% as suitable, and 45% as unsuitable. The selection of the final landfill site, however, requires further field research.

Building dismantlement and site remediation at the Apollo Fuel Plant: When is technology the answer?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walton, L.

1995-01-01

The Apollo fuel plant was located in Pennsylvania on a site known to have been used continuously for stell production from before the Civil War until after World War II. Then the site became a nuclear fuel chemical processing plants. Finally it was used to convert uranium hexafluoride to various oxide fuel forms. After the fuel manufacturing operations were teminated, the processing equipment was partially decontaminated, removed, packaged and shipped to a licensed low-level radioactive waste burial site. The work was completed in 1984. In 1990 a detailed site characterization was initiated to establishe the extent of contamination and tomore » plan the building dismantlement and soil remediation efforts. This article discusses the site characterization and remedial action at the site in the following subsections: characterization; criticality control; mobile containment; soil washing; in-process measurements; and the final outcome of the project.« less

Strategy for Ranking the Science Value of the Surface of Asteroid 101955 Bennu for Sample Site Selection for Osiris-REx

NASA Technical Reports Server (NTRS)

Nakamura-Messenger, K.; Connolly, H. C., Jr.; Lauretta, D. S.

2014-01-01

OSRIS-REx is NASA's New Frontiers 3 sample return mission that will return at least 60 g of pristine surface material from near-Earth asteroid 101955 Bennu in September 2023. The scientific value of the sample increases enormously with the amount of knowledge captured about the geological context from which the sample is collected. The OSIRIS-REx spacecraft is highly maneuverable and capable of investigating the surface of Bennu at scales down to the sub-cm. The OSIRIS-REx instruments will characterize the overall surface geology including spectral properties, microtexture, and geochemistry of the regolith at the sampling site in exquisite detail for up to 505 days after encountering Bennu in August 2018. The mission requires at the very minimum one acceptable location on the asteroid where a touch-and-go (TAG) sample collection maneuver can be successfully per-formed. Sample site selection requires that the follow-ing maps be produced: Safety, Deliverability, Sampleability, and finally Science Value. If areas on the surface are designated as safe, navigation can fly to them, and they have ingestible regolith, then the scientific value of one site over another will guide site selection.

Dynamics of the EAG1 K+ channel selectivity filter assessed by molecular dynamics simulations.

PubMed

Bernsteiner, Harald; Bründl, Michael; Stary-Weinzinger, Anna

2017-02-26

EAG1 channels belong to the KCNH family of voltage gated potassium channels. They are expressed in several brain regions and increased expression is linked to certain cancer types. Recent cryo-EM structure determination finally revealed the structure of these channels in atomic detail, allowing computational investigations. In this study, we performed molecular dynamics simulations to investigate the ion binding sites and the dynamical behavior of the selectivity filter. Our simulations suggest that sites S2 and S4 form stable ion binding sites, while ions placed at sites S1 and S3 rapidly switched to sites S2 and S4. Further, ions tended to dissociate away from S0 within less than 20 ns, due to increased filter flexibility. This was followed by water influx from the extracellular side, leading to a widening of the filter in this region, and likely non-conductive filter configurations. Simulations with the inactivation-enhancing mutant Y464A or Na + ions lead to trapped water molecules behind the SF, suggesting that these simulations captured early conformational changes linked to C-type inactivation. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Research of diagnosis sensors fault based on correlation analysis of the bridge structural health monitoring system

NASA Astrophysics Data System (ADS)

Hu, Shunren; Chen, Weimin; Liu, Lin; Gao, Xiaoxia

2010-03-01

Bridge structural health monitoring system is a typical multi-sensor measurement system due to the multi-parameters of bridge structure collected from the monitoring sites on the river-spanning bridges. Bridge structure monitored by multi-sensors is an entity, when subjected to external action; there will be different performances to different bridge structure parameters. Therefore, the data acquired by each sensor should exist countless correlation relation. However, complexity of the correlation relation is decided by complexity of bridge structure. Traditionally correlation analysis among monitoring sites is mainly considered from physical locations. unfortunately, this method is so simple that it cannot describe the correlation in detail. The paper analyzes the correlation among the bridge monitoring sites according to the bridge structural data, defines the correlation of bridge monitoring sites and describes its several forms, then integrating the correlative theory of data mining and signal system to establish the correlation model to describe the correlation among the bridge monitoring sites quantificationally. Finally, The Chongqing Mashangxi Yangtze river bridge health measurement system is regards as research object to diagnosis sensors fault, and simulation results verify the effectiveness of the designed method and theoretical discussions.

Knowledge and Valorization of Historical Sites Through 3d Documentation and Modeling

NASA Astrophysics Data System (ADS)

Farella, E.; Menna, F.; Nocerino, E.; Morabito, D.; Remondino, F.; Campi, M.

2016-06-01

The paper presents the first results of an interdisciplinary project related to the 3D documentation, dissemination, valorization and digital access of archeological sites. Beside the mere 3D documentation aim, the project has two goals: (i) to easily explore and share via web references and results of the interdisciplinary work, including the interpretative process and the final reconstruction of the remains; (ii) to promote and valorize archaeological areas using reality-based 3D data and Virtual Reality devices. This method has been verified on the ruins of the archeological site of Pausilypon, a maritime villa of Roman period (Naples, Italy). Using Unity3D, the virtual tour of the heritage site was integrated and enriched with the surveyed 3D data, text documents, CAAD reconstruction hypotheses, drawings, photos, etc. In this way, starting from the actual appearance of the ruins (panoramic images), passing through the 3D digital surveying models and several other historical information, the user is able to access virtual contents and reconstructed scenarios, all in a single virtual, interactive and immersive environment. These contents and scenarios allow to derive documentation and geometrical information, understand the site, perform analyses, see interpretative processes, communicate historical information and valorize the heritage location.

A quantum chemical study for exploring the inhibitory effect of nitrogen containing species on the adsorption of polynuclear aromatic hydrocarbons over a Bronsted acid site

NASA Astrophysics Data System (ADS)

Celis-Cornejo, C. M.; Garnica Mantilla, M. M.; Baldovino-Medrano, V. G.; Ramírez-Caballero, G. E.

2016-08-01

The analysis of the inhibitory effect of nitrogenated compounds on the hydroprocessing and hydropurification of oil derived fuels is important to produce cleaner fuels. In this work, density functional theory calculations were performed to investigate the effect of the nitrogen containing molecules on the adsorption of Polynuclear Aromatic Hydrocarbons (PAHs). Mordenite was chosen as a zeolitic structure for simulating a Bronsted acid site. The character of the acid site was confirmed by both a vibrational frequency calculation and a Bader charge analysis. From the adsorption calculations, it was found that the adsorption energy of PAHs increases with the number of aromatic rings in the structure. Also, the nitrogen containing species possibly inhibit more extensively two and three rings PAHs because of their lower adsorption energies. Finally, it was observed that the nitrogen species tend to drag the proton from the mordenite acid site. This explains the inhibitory effect in the adsorption of PAHs and contributes to understanding the dynamics of hydrocarbon hydroprocessing in refineries.

Rational Synthesis of Hollow Prussian Blue Analogue Through Coordination Replication and Controlled-Etching for Cs-Ion Removal.

PubMed

Xu, Jun; Bu, Fan-Xing; Guo, Yi-Fei; Zhang, Wei; Hu, Ming; Jiang, Ji-Sen

2018-05-01

Radioactive cesium pollution have received considerable attention due to the increasing risks in development of the nuclear power plants in the world. Although various functional porous materials are utilized to adsorb Cs+ ions in water, Prussian blue analogues (PBAs) are an impressive class of candidates because of their super affinity of Cs+ ions. The adsorption ability of the PBAs strongly relate to the mesostructure and interstitial sites. To design a hollow PBA with large number of interstitial sites, the traditional hollowing methods are not suitable owing to the difficulty in processing the specific PBAs with large number of interstitial sites. In this work, we empolyed a rational strategy which was to form a "metal oxide"@"PBA" core-shell structure via coordination replication at first, then utilized a mild etching to remove the metal oxide core, led to hollow PBA finally. The obtained hollow PBAs were of high crystallinity and large number of interstitial sites, showing a super adsorption performance for Cs+ ions (221.6 mg/g) within a short period (10 min).

Site-Specific Analyses for Demonstrating Compliance with 10 CFR 61 Performance Objectives - 12179

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grossman, C.J.; Esh, D.W.; Yadav, P.

2012-07-01

The U.S. Nuclear Regulatory Commission (NRC) is proposing to amend its regulations at 10 CFR Part 61 to require low-level radioactive waste disposal facilities to conduct site-specific analyses to demonstrate compliance with the performance objectives in Subpart C. The amendments would require licensees to conduct site-specific analyses for protection of the public and inadvertent intruders as well as analyses for long-lived waste. The amendments would ensure protection of public health and safety, while providing flexibility to demonstrate compliance with the performance objectives, for current and potential future waste streams. NRC staff intends to submit proposed rule language and associated regulatorymore » basis to the Commission for its approval in early 2012. The NRC staff also intends to develop associated guidance to accompany any proposed amendments. The guidance is intended to supplement existing low-level radioactive waste guidance on issues pertinent to conducting site-specific analyses to demonstrate compliance with the performance objectives. The guidance will facilitate implementation of the proposed amendments by licensees and assist competent regulatory authorities in reviewing the site-specific analyses. Specifically, the guidance provides staff recommendations on general considerations for the site-specific analyses, modeling issues for assessments to demonstrate compliance with the performance objectives including the performance assessment, intruder assessment, stability assessment, and analyses for long-lived waste. This paper describes the technical basis for changes to the rule language and the proposed guidance associated with implementation of the rule language. The NRC staff, per Commission direction, intends to propose amendments to 10 CFR Part 61 to require licensees to conduct site-specific analyses to demonstrate compliance with performance objectives for the protection of public health and the environment. The amendments would require a performance assessment to demonstrate protection of the general population from releases of radioactivity, an assessment to demonstrate protection of a potential inadvertent intruder, and a long-term analysis to assess how the design of the facility considers the potential radiological impacts associated with disposal of long-lived waste streams. Concurrently, the NRC staff intends to propose associated guidance to facilitate the implementation of the requirements to conduct site-specific analyses. In proposing these amendments to the regulation and associated guidance, the NRC staff has conducted extensive public outreach since 2009 including three public meetings and four briefings of the NRC's Advisory Committee on Reactor Safeguards. The NRC staff plans to submit the proposed amendments to the regulations to the Commission in early 2012. Subsequently, the proposed amendments and associated guidance would be published in the Federal Register for public comment pending approval of the proposed amendments to the regulations by the Commission. Following the public comment period, NRC staff plans to address public comments and revise, as necessary, the regulations and associated guidance before publishing a final rule, which is anticipated in 2013. (authors)« less

Final Status Survey Report for Corrective Action Unit 117 - Pluto Disassembly Facility, Building 2201, Nevada National Security Site, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jeremy Gwin and Douglas Frenette

This document contains the process knowledge, radiological data and subsequent statistical methodology and analysis to support approval for the radiological release of Corrective Action Unit (CAU) 117 – Pluto Disassembly Facility, Building 2201 located in Area 26 of the Nevada National Security Site (NNSS). Preparations for release of the building began in 2009 and followed the methodology described in the Multi-Agency Radiation Survey and Site Investigation Manual (MARSSIM). MARSSIM is the DOE approved process for release of Real Property (buildings and landmasses) to a set of established criteria or authorized limits. The pre-approved authorized limits for surface contamination values andmore » corresponding assumptions were established by DOE O 5400.5. The release criteria coincide with the acceptance criteria of the U10C landfill permit. The U10C landfill is the proposed location to dispose of the radiologically non-impacted, or “clean,” building rubble following demolition. However, other disposition options that include the building and/or waste remaining at the NNSS may be considered providing that the same release limits apply. The Final Status Survey was designed following MARSSIM guidance by reviewing historical documentation and radiological survey data. Following this review a formal radiological characterization survey was performed in two phases. The characterization revealed multiple areas of residual radioactivity above the release criteria. These locations were remediated (decontaminated) and then the surface activity was verified to be less than the release criteria. Once remediation efforts had been successfully completed, a Final Status Survey Plan (10-015, “Final Status Survey Plan for Corrective Action Unit 117 – Pluto Disassembly Facility, Building 2201”) was developed and implemented to complete the final step in the MARSSIM process, the Final Status Survey. The Final Status Survey Plan consisted of categorizing each individual room into one of three categories: Class 1, Class 2 or Class 3 (a fourth category is a “Non-Impacted Class” which in the case of Building 2201 only pertained to exterior surfaces of the building.) The majority of the rooms were determined to fall in the less restrictive Class 3 category, however, Rooms 102, 104, 106, and 107 were identified as containing Class 1 and 2 areas. Building 2201 was divided into “survey units” and surveyed following the requirements of the Final Status Survey Plan for each particular class. As each survey unit was completed and documented, the survey results were evaluated. Each sample (static measurement) with units of counts per minute (cpm) was corrected for the appropriate background and converted to a value with units of dpm/100 cm2. With a surface contamination value in the appropriate units, it was compared to the surface contamination limits, or in this case the derived concentration guideline level (DCGLw). The appropriate statistical test (sign test) was then performed. If the survey unit was statistically determined to be below the DCGLw, then the survey unit passed and the null hypothesis (that the survey unit is above limits) was rejected. If the survey unit was equal to or below the critical value in the sign test, the null hypothesis was not rejected. This process was performed for all survey units within Building 2201. A total of thirty-three “Class 1,” four “Class 2,” and one “Class 3” survey units were developed, surveyed, and evaluated. All survey units successfully passed the statistical test. Building 2201 meets the release criteria commensurate with the Waste Acceptance Criteria (for radiological purposes) of the U10C landfill permit residing within NNSS boundaries. Based on the thorough statistical sampling and scanning of the building’s interior, Building 2201 may be considered radiologically “clean,” or free of contamination.« less

Revised FINAL–REPORT NO. 2: INDEPENDENT CONFIRMATORY SURVEY SUMMARY AND RESULTS FOR THE ENRICO FERMI ATOMIC POWER PLANT, UNIT 1, NEWPORT, MICHIGAN (DOCKET NO. 50 16; RFTA 10-004) 2018-SR-02-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erika Bailey

2011-10-27

The Enrico Fermi Atomic Power Plant, Unit 1 (Fermi 1) was a fast breeder reactor design that was cooled by sodium and operated at essentially atmospheric pressure. On May 10, 1963, the Atomic Energy Commission (AEC) granted an operating license, DPR-9, to the Power Reactor Development Company (PRDC), a consortium specifically formed to own and operate a nuclear reactor at the Fermi 1 site. The reactor was designed for a maximum capability of 430 megawatts (MW); however, the maximum reactor power with the first core loading (Core A) was 200 MW. The primary system was filled with sodium in Decembermore » 1960 and criticality was achieved in August 1963. The reactor was tested at low power during the first couple years of operation. Power ascension testing above 1 MW commenced in December 1965 immediately following the receipt of a high-power operating license. In October 1966 during power ascension, zirconium plates at the bottom of the reactor vessel became loose and blocked sodium coolant flow to some fuel subassemblies. Two subassemblies started to melt and the reactor was manually shut down. No abnormal releases to the environment occurred. Forty-two months later after the cause had been determined, cleanup completed, and the fuel replaced, Fermi 1 was restarted. However, in November 1972, PRDC made the decision to decommission Fermi 1 as the core was approaching its burn-up limit. The fuel and blanket subassemblies were shipped off-site in 1973. Following that, the secondary sodium system was drained and sent off-site. The radioactive primary sodium was stored on-site in storage tanks and 55 gallon (gal) drums until it was shipped off-site in 1984. The initial decommissioning of Fermi 1 was completed in 1975. Effective January 23, 1976, DPR-9 was transferred to the Detroit Edison Company (DTE) as a 'possession only' license (DTE 2010a). This report details the confirmatory activities performed during the second Oak Ridge Institute for Science and Education (ORISE) site visit to Fermi 1 in November 2010. The survey was strategically planned during a Unit 2 (Fermi 2) outage to take advantage of decreased radiation levels that were observed and attributed to Fermi 2 from the operating unit during the first site visit. However, during the second visit there were elevated radiation levels observed and attributed to the partially dismantled Fermi 1 reactor vessel and a waste storage box located on the 3rd floor of the Fermi 1 Turbine Building. Confirmatory surveys (unshielded) performed directly in the line of sight of these areas were affected. The objective of the confirmatory survey was to verify that the final radiological conditions were accurately and adequately described in Final Status Survey (FSS) documentation, relative to the established release criteria. This objective was achieved by performing document reviews, as well as independent measurements and sampling. Specifically, documentation of the planning, implementation, and results of the FSS were evaluated; side-by-side FSS measurement and source comparisons were performed; site areas were evaluated relative to appropriate FSS classification; and areas were assessed for residual, undocumented contamination.« less

Data fusion strategies for hazard detection and safe site selection for planetary and small body landings

NASA Astrophysics Data System (ADS)

Câmara, F.; Oliveira, J.; Hormigo, T.; Araújo, J.; Ribeiro, R.; Falcão, A.; Gomes, M.; Dubois-Matra, O.; Vijendran, S.

2015-06-01

This paper discusses the design and evaluation of data fusion strategies to perform tiered fusion of several heterogeneous sensors and a priori data. The aim is to increase robustness and performance of hazard detection and avoidance systems, while enabling safe planetary and small body landings anytime, anywhere. The focus is on Mars and asteroid landing mission scenarios and three distinct data fusion algorithms are introduced and compared. The first algorithm consists of a hybrid camera-LIDAR hazard detection and avoidance system, the H2DAS, in which data fusion is performed at both sensor-level data (reconstruction of the point cloud obtained with a scanning LIDAR using the navigation motion states and correcting the image for motion compensation using IMU data), feature-level data (concatenation of multiple digital elevation maps, obtained from consecutive LIDAR images, to achieve higher accuracy and resolution maps while enabling relative positioning) as well as decision-level data (fusing hazard maps from multiple sensors onto a single image space, with a single grid orientation and spacing). The second method presented is a hybrid reasoning fusion, the HRF, in which innovative algorithms replace the decision-level functions of the previous method, by combining three different reasoning engines—a fuzzy reasoning engine, a probabilistic reasoning engine and an evidential reasoning engine—to produce safety maps. Finally, the third method presented is called Intelligent Planetary Site Selection, the IPSIS, an innovative multi-criteria, dynamic decision-level data fusion algorithm that takes into account historical information for the selection of landing sites and a piloting function with a non-exhaustive landing site search capability, i.e., capable of finding local optima by searching a reduced set of global maps. All the discussed data fusion strategies and algorithms have been integrated, verified and validated in a closed-loop simulation environment. Monte Carlo simulation campaigns were performed for the algorithms performance assessment and benchmarking. The simulations results comprise the landing phases of Mars and Phobos landing mission scenarios.

Characterization and classification of South American land cover types using satellite data

NASA Technical Reports Server (NTRS)

Townshend, J. R. G.; Justice, C. O.; Kalb, V.

1987-01-01

Various methods are compared for carrying out land cover classifications of South America using multitemporal Advanced Very High Resolution Radiometer data. Fifty-two images of the normalized difference vegetation index (NDVI) from a 1-year period are used to generate multitemporal data sets. Three main approaches to land cover classification are considered, namely the use of the principal components transformed images, the use of a characteristic curves procedure based on NDVI values plotted against time, and finally application of the maximum likelihood rule to multitemporal data sets. Comparison of results from training sites indicates that the last approach yields the most accurate results. Despite the reliance on training site figures for performance assessment, the results are nevertheless extremely encouraging, with accuracies for several cover types exceeding 90 per cent.

Installation-restoration program. Phase 2. Confirmation/quantification. Stage 1 for Shaw Air Force Base, South Carolina. Final report, January 1984-October 1986

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alexander, W.J.; Liddle, S.K.

1986-09-01

The primary objectives of this project were to collect and analyze groundwater, surface water, and sediment samples and to perform an initial characterization of the hydrogeochemical regime at potential contamination sites on Shaw Air Force Base near Sumter, South Carolina. This study constituted Phase II of the U.S. Air Force Installation Restoration Program (IRP). Five potential sources of groundwater pollution were studied. The evaluation primarily included the drilling of soil test borings, the installation, development, and sampling of groundwater monitoring wells, and the analyses of soil, surface water, and groundwater samples. Also used in the study were field measurements ofmore » water quality, water-level measurements site observations, published hydrogeologic data and Shaw AFB documents.« less

Meteorological Predictions in Support of the Mars Science Laboratory Entry, Descent and Landing

NASA Astrophysics Data System (ADS)

Rothchild, A.; Rafkin, S. C.; Pielke, R. A., Sr.

2010-12-01

The Mars Science Laboratory (MSL) entry, descent, and landing (EDL) system employs a standard parachute strategy followed by a new sky crane concept where the rover is lowered to the ground via a tether from a hovering entry vehicle. As with previous missions, EDL system performance is sensitive to atmospheric conditions. While some observations characterizing the mean, large-scale atmospheric temperature and density data are available, there is effectively no information on the atmospheric conditions and variability at the scale that directly affects the spacecraft. In order to evaluate EDL system performance and to assess landing hazards and risk, it is necessary to simulate the atmosphere with a model that provides data at the appropriate spatial and temporal scales. Models also permit the study of the impact of the highly variable atmospheric dust loading on temperature, density and winds. There are four potential MSL landing sites: Mawrth Valle (22.3 N, 16.5W) , Gale Crater (5.4S, 137.7E), Holden Crater (26.1S, 34W), and Eberswalde Crater (24S, 33W). The final selection of the landing site will balance potential science return against landing and operational risk. Atmospheric modeling studies conducted with the Mars Regional Atmospheric Modeling System (MRAMS) is an integral part of the selection process. At each of the landing sites, a variety of simulations are conducted. The first type of simulations provide baseline predictions under nominal atmospheric dust loading conditions within the landing site window of ~Ls 150-170. The second type of simulation explores situations with moderate and high global atmospheric dust loading. The final type of simulation investigates the impact of local dust disturbances at the landing site. Mean and perturbation fields from each type of simulation at each of the potential landing sites are presented in comparison with the engineering performance limitations for the MSL EDL system. Within the lowest scale height, winds are strongly influenced by the local and regional topography and are highly variable in both space and time. Convective activity in the afternoon produces deep vertical circulations anchored primarily to topography. Aloft, winds become increasingly dominated by the large-scale circulation, but with gravity wave perturbations forced by both topography and boundary layer convective activity. The mean density field is tied directly to the level of dust loading; higher dust results in decreased densities and overall warming of the atmospheric column. In local and regional dust storm scenarios, winds are found to be enhanced, particularly in regions of active dust lifting. Local reductions in density are also pronounced. At present, the predicted mean and perturbation fields from all the simulations appear to fall within the engineering requirements, but not always comfortably so. This is in contrast to proposed landing sites for the Mars Exploration Rover mission, where the atmospheric environment presented unacceptable risk. Ongoing work is underway to confirm that atmospheric conditions will permit safe EDL operations with a tolerable level of risk.

10 CFR 2.629 - Finality of partial decision on site suitability issues in a combined license proceeding.

Code of Federal Regulations, 2014 CFR

2014-01-01

...), the Director of the Office of New Reactors or the Director of the Office of Nuclear Reactor Regulation... 10 Energy 1 2014-01-01 2014-01-01 false Finality of partial decision on site suitability issues in a combined license proceeding. 2.629 Section 2.629 Energy NUCLEAR REGULATORY COMMISSION AGENCY RULES...

10 CFR 2.629 - Finality of partial decision on site suitability issues in a combined license proceeding.

Code of Federal Regulations, 2013 CFR

2013-01-01

...), the Director of the Office of New Reactors or the Director of the Office of Nuclear Reactor Regulation... 10 Energy 1 2013-01-01 2013-01-01 false Finality of partial decision on site suitability issues in a combined license proceeding. 2.629 Section 2.629 Energy NUCLEAR REGULATORY COMMISSION AGENCY RULES...

Building America Industrialized Housing Partnership (BAIHP II)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abernethy, Bob; Chandra, Subrato; Baden, Steven

2010-11-30

This report summarizes the work conducted by the Building America Industrialized Housing Partnership (BAIHP - www.baihp.org) during the final budget period (BP5) of our contract, January 1, 2010 to November 30, 2010. Highlights from the four previous budget periods are included for context. BAIHP is led by the Florida Solar Energy Center (FSEC) of the University of Central Florida. With over 50 Industry Partners including factory and site builders, work in BP5 was performed in six tasks areas: Building America System Research Management, Documentation and Technical Support; System Performance Evaluations; Prototype House Evaluations; Initial Community Scale Evaluations; Project Closeout, Finalmore » Review of BA Communities; and Other Research Activities.« less

The Viking project. [summary

NASA Technical Reports Server (NTRS)

Soffen, G. A.

1977-01-01

The Viking project launched two unmanned spacecraft to Mars in 1975 for scientific exploration with special emphasis on the search for life. Each spacecraft consisted of an orbiter and a lander. The landing sites were finally selected after the spacecraft were in orbit. Thirteen investigations were performed: three mapping experiments from the orbiter, one atmospheric investigation during the lander entry phase, eight experiments on the surface of the planet, and one using the spacecraft radio and radar systems. The experiments on the surface dealt principally with biology, chemistry, geology, and meteorology. Seventy-eight scientists have participated in the 13 teams performing these experiments. This paper is a summary of the project and an introduction to the articles that follow.

Polyadenylation site prediction using PolyA-iEP method.

PubMed

Kavakiotis, Ioannis; Tzanis, George; Vlahavas, Ioannis

2014-01-01

This chapter presents a method called PolyA-iEP that has been developed for the prediction of polyadenylation sites. More precisely, PolyA-iEP is a method that recognizes mRNA 3'ends which contain polyadenylation sites. It is a modular system which consists of two main components. The first exploits the advantages of emerging patterns and the second is a distance-based scoring method. The outputs of the two components are finally combined by a classifier. The final results reach very high scores of sensitivity and specificity.

Knowledge-based systems in Japan

NASA Technical Reports Server (NTRS)

Feigenbaum, Edward; Engelmore, Robert S.; Friedland, Peter E.; Johnson, Bruce B.; Nii, H. Penny; Schorr, Herbert; Shrobe, Howard

1994-01-01

This report summarizes a study of the state-of-the-art in knowledge-based systems technology in Japan, organized by the Japanese Technology Evaluation Center (JTEC) under the sponsorship of the National Science Foundation and the Advanced Research Projects Agency. The panel visited 19 Japanese sites in March 1992. Based on these site visits plus other interactions with Japanese organizations, both before and after the site visits, the panel prepared a draft final report. JTEC sent the draft to the host organizations for their review. The final report was published in May 1993.

Standardized Automated CO2/H2O Flux Systems for Individual Research Groups and Flux Networks

NASA Astrophysics Data System (ADS)

Burba, George; Begashaw, Israel; Fratini, Gerardo; Griessbaum, Frank; Kathilankal, James; Xu, Liukang; Franz, Daniela; Joseph, Everette; Larmanou, Eric; Miller, Scott; Papale, Dario; Sabbatini, Simone; Sachs, Torsten; Sakai, Ricardo; McDermitt, Dayle

2017-04-01

In recent years, spatial and temporal flux data coverage improved significantly, and on multiple scales, from a single station to continental networks, due to standardization, automation, and management of data collection, and better handling of the extensive amounts of generated data. With more stations and networks, larger data flows from each station, and smaller operating budgets, modern tools are required to effectively and efficiently handle the entire process. Such tools are needed to maximize time dedicated to authoring publications and answering research questions, and to minimize time and expenses spent on data acquisition, processing, and quality control. Thus, these tools should produce standardized verifiable datasets and provide a way to cross-share the standardized data with external collaborators to leverage available funding, promote data analyses and publications. LI-COR gas analyzers are widely used in past and present flux networks such as AmeriFlux, ICOS, AsiaFlux, OzFlux, NEON, CarboEurope, and FluxNet-Canada, etc. These analyzers have gone through several major improvements over the past 30 years. However, in 2016, a three-prong development was completed to create an automated flux system which can accept multiple sonic anemometer and datalogger models, compute final and complete fluxes on-site, merge final fluxes with supporting weather soil and radiation data, monitor station outputs and send automated alerts to researchers, and allow secure sharing and cross-sharing of the station and data access. Two types of these research systems were developed: open-path (LI-7500RS) and enclosed-path (LI-7200RS). Key developments included: • Improvement of gas analyzer performance • Standardization and automation of final flux calculations onsite, and in real-time • Seamless integration with latest site management and data sharing tools In terms of the gas analyzer performance, the RS analyzers are based on established LI-7500/A and LI-7200 models, and the improvements focused on increased stability in the presence of contamination, refining temperature control and compensation, and providing more accurate fast gas concentration measurements. In terms of the flux calculations, improvements focused on automating the on-site flux calculations using EddyPro® software run by a weatherized fully digital microcomputer, SmartFlux2. In terms of site management and data sharing, the development focused on web-based software, FluxSuite, which allows real-time station monitoring and data access by multiple users. The presentation will describe details for the key developments and will include results from field tests of the RS gas analyzer models in comparison with older models and control reference instruments.

Road-map to plan and structure the preliminary site investigation program for a geological repository in Japan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deguchi, Akira; Tsuchi, Hiroyuki; Kitayama, Kazumi

2007-07-01

Available in abstract form only. Full text of publication follows: A stepwise site selection process has been adopted for geological disposal of HLW in Japan. Literature surveys (LS), followed by preliminary investigations (PI) and, finally, detailed investigations (DI) in underground facilities will be carried out in the successive selection stages. In the PI stage, surface-based investigations such as borehole surveys and geophysical prospecting will be implemented with two main objectives. The first is to obtain information relating to legal requirements on siting, such as the occurrence of igneous or fault activity, and to confirm the extremely low likelihood of adversemore » impacts on the candidate site resulting from such phenomena. The second is to obtain the information required for the design and performance assessment of the engineered barrier system and the repository. In order to implement these preliminary investigations rigorously and efficiently within the constraints of a limited time period, budget and resources, PI planning before commencing investigations and on-site PI management during the investigation phase are very important issues. The planning and management of PI have to be performed by NUMO staff, but not all staff have sufficient experience in the range of disciplines involved. NUMO therefore decided to compile existing knowledge and experience in the planning and management of investigations in the form of manuals to be used to improve and maintain internal expertise. Experts with experience in overseas investigation programs were requested to prepare these manuals. This paper outlines the structure and scope of the upper level manual (road-map) and discusses NUMO's experience in applying it in 'dry-runs' to model sites. (authors)« less

Disposal site quality team final report

DOT National Transportation Integrated Search

2001-09-01

The disposal site quality team was formed in July 2000 to address Caltrans (Department) and Federal Highway Administration (FHWA) policies on disposal, staging, and borrow areas (DSB), including plant sites, contractor yards, and access roads. Caltra...

Hardware test program for evaluation of baseline range/range rate sensor concept

NASA Technical Reports Server (NTRS)

Pernic, E.

1985-01-01

The test program Phase II effort provides additional design information in terms of range and range rate (R/R) sensor performance when observing and tracking a typical spacecraft target. The target used in the test program was a one-third scale model of the Hubble Space Telescope (HST) available at the MSFC test site where the tests were performed. A modified Bendix millimeter wave radar served as the R/R sensor test bed for evaluation of range and range rate tracking performance, and generation of radar signature characteristics of the spacecraft target. A summary of program test results and conclusions are presented along with detailed description of the Bendix test bed radar with accompaning instrumentation. The MSFC test site and facilities are described. The test procedures used to establish background levels, and the calibration procedures used in the range accuracy tests and RCS (radar cross section) signature measurements, are presented and a condensed version of the daily log kept during the 5 September through 17 September test period is also presented. The test program results are given starting with the RCS signature measurements, then continuing with range measurement accuracy test results and finally the range and range rate tracking accuracy test results.

75 FR 65558 - Final Supplemental Environmental Impact Statement, Single Nuclear Unit at the Bellefonte Plant...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-25

... TENNESSEE VALLEY AUTHORITY Final Supplemental Environmental Impact Statement, Single Nuclear Unit... Environmental Impact Statement for a Single Nuclear Unit at the Bellefonte Plant Site (final SEIS) on September... the ROD. TVA prepared the final SEIS to update the extensive environmental information and analyses...

Analysis of organic compounds in aqueous samples of former ammunition plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levsen, K.; Preiss, A.; Berger-Preiss, E.

1995-12-31

In Germany, a large number of sites exist where ammunition was produced before and in particular during World War II. These former production sites represent a particular threat to the environment because these plants were constructed and operated under war conditions, where production was far more important than protection of the health of the (in general forced) workers and the environment. New approaches are presented for the extraction and analysis of explosives and related compounds in aqueous samples from former ammunition production sites. Quantitative extraction of nitro aromatics but also of the polar nitroamines such as RDX and HMX ismore » achieved by solid phase extraction with styrene-divinylbenzene polymers (Lichrolut EN). Proton nuclear magnetic resonance ({sup 1}H-NMR) has been used to identify and quantify unknowns in ammunition waste water. Finally, automated multiple development (AMD) high performance thin layer chromatography was applied for the first time to the analysis of this compound class.« less

Regulation of alternative mRNA splicing: old players and new perspectives.

PubMed

Dvinge, Heidi

2018-06-01

Nearly all human multi-exon genes are subject to alternative splicing in one or more cell types. The splicing machinery, therefore, has to select between multiple splice sites in a context-dependent manner, relying on sequence features in cis and trans-acting splicing regulators that either promote or repress splice site recognition and spliceosome assembly. However, the functional coupling between multiple gene regulatory layers signifies that splicing can also be modulated by transcriptional or epigenetic characteristics. Other, less obvious, aspects of alternative splicing have come to light in recent years, often involving core components of the spliceosome previously thought to perform a basal rather than a regulatory role in splicing. Together this paints a highly dynamic picture of splicing regulation, where the final splice site choice is governed by the entire transcriptional environment of a gene and its cellular context. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Clinicians performing cosmetic surgery in the community: a nationwide analysis of physician certification.

PubMed

Barr, Jason S; Sinno, Sammy; Cimino, Marcus; Saadeh, Pierre B

2015-01-01

Practitioners who are not board-certified by the American Board of Plastic Surgery are practicing cosmetic surgery. The extent of this issue across the United States has yet to be examined in detail. A systematic search using Google was performed to evaluate the qualifications of clinicians marketing themselves as plastic surgeons. For every U.S. state, the following searches were performed: [state] plastic surgery, [state] cosmetic surgery, and [state] aesthetic surgery. The first 50 Web sites returned for each search were visited and scrutinized using the American Society of Plastic Surgeons and American Board of Plastic Surgery Web sites. In total, 7500 Web sites were visited, yielding 2396 board-certified plastic surgeons (77.9 percent of all practitioners). There were 284 board-certified ear, nose, and throat surgeons, 61 (21.5 percent) of whom practice outside their scope; 106 board-certified general surgeons, 100 (94.3 percent) of whom practice outside their scope; 104 board-certified oral and maxillofacial surgery surgeons, 68 (65.4 percent) of whom practice outside their scope; 70 board-certified ophthalmologists/oculoplastic surgeons, 49 (70 percent) of whom practice outside their scope; and 74 board-certified dermatologists, 36 (48.6 percent) of whom practice outside their scope. There were also 16 internal medicine doctors, 13 obstetrics and gynecology physicians, six emergency medicine physicians, three pediatricians, two urologists, two anesthesiologists, and finally one phlebotomist; all of these practitioners practice outside their scope as defined by Accreditation Council for Graduate Medical Education core competencies. Many clinicians performing cosmetic surgery are not board-certified. This finding has important implications for patient safety.

Superfund Record of Decision (EPA Region 5): Novaco Industries, MI. (First remedial action), (Amendment), September 1991. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The 2.6-acre Novaco Industries site is a one building site in Temperance, Michigan. Land use in the area is predominantly residential and agricultural. The estimated 85 residences located within 1/2 mile of the site use the underlying sand/gravel and limestone aquifer as their drinking water supply. A 1986 Record of Decision (ROD) addressed a final remedy for ground water contamination and provided for ground water pumping and treatment using electrochemical reduction/ion exchange polishing, followed by onsite discharge to surface water. The ROD amends the 1986 ROD. The amended remedial action for the site is no further action.

Report of the Peer Review Panel on the early site suitability evaluation of the Potential Repository Site at Yucca Mountain, Nevada; Yucca Mountain Site Characterization Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1992-01-01

The US Department of Energy (DOE) Yucca mountain Site Characterization Project Office (YMPO) assigned Science Applications International Corporation (SAIC), the Technical and Management Support Services (T&MSS) contractor to the YmPo, the task of conducting an Early Site Suitability Evaluation (ESSE) of the Yucca mountain site as a potential site for a high-level radioactive waste repository. First, the assignment called for the development of a method to evaluate a single site against the DOE General Guidelines for Recommendation of Sites for Nuclear Waste Repositories, 10 CFR Part 960. Then, using this method, an evaluation team, the ESSE Core Team, of seniormore » YMP scientists, engineers, and technical experts, evaluated new information obtained about the site since publication of the final Environmental Assessment (DOE, 1986) to determine if new suitability/unsuitability findings could be recommended. Finally, the Core Team identified further information and analyses needed to make final determinations for each of the guidelines. As part of the task, an independent peer review of the ESSE report has been conducted. Expertise was solicited that covered the entire spectrum of siting guidelines in 10 CFR Part 960 in order to provide a complete, in-depth critical review of the data evaluated and cited in the ESSE report, the methods used to evaluate the data, and the conclusions and recommendations offered by the report. Fourteen nationally recognized technical experts (Table 2) served on the Peer Review Panel. The comments from the Panel and the responses prepared by the ESSE Core Team, documented on formal Comment Response Forms, constitute the body of this document.« less

Final Report: Technical Assistance for the Kearsarge Metallurgical Corporation Superfund Site, Conway, New Hampshire, EPA Region 1

EPA Pesticide Factsheets

This report reviews and provides recommendations for a long-term groundwater monitoring network for the Kearsarge Metallurgical Corporation Superfund site (KMC site). The KMC site is a former foundry and metal fabrication facility in Conway, New Hampshire.

Final 2014 Remedial Action Report Project Chariot, Cape Thompson, Alaska

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2015-03-01

This report was prepared to document remedial action (RA) work performed at the former Project Chariot site located near Cape Thompson, Alaska during 2014. The work was managed by the U.S. Army Corps of Engineers (USACE) Alaska District for the U.S. Department of Energy (DOE) Office of Legacy Management (LM). Due to the short field season and the tight barge schedule, all field work was conducted at the site July 6 through September 12, 2014. Excavation activities occurred between July 16 and August 26, 2014. A temporary field camp was constructed at the site prior to excavation activities to accommodatemore » the workers at the remote, uninhabited location. A total of 785.6 tons of petroleum, oil, and lubricants (POL)-contaminated soil was excavated from four former drill sites associated with test holes installed circa 1960. Diesel was used in the drilling process during test hole installations and resulted in impacts to surface and subsurface soils at four of the five sites (no contamination was identified at Test Hole Able). Historic information is not definitive as to the usage for Test Hole X-1; it may have actually been a dump site and not a drill site. In addition to the contaminated soil, the steel test hole casings were decommissioned and associated debris was removed as part of the remedial effort.« less

Characterization and remediation of 91B radioactive waste sites under performance based contracts at Lackland Air Force Base, San Antonio, Texas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trujillo, P.A.; Anderson, K.D.

2007-07-01

This paper describes the challenges behind the implementation of the characterization, remediation, and the Site Closure for three 91b Radioactive Wastes under a Performance Based Contract at Lackland Air Force Base, San Antonio, Texas. The Defense Environmental Restoration Program (DERP) was established by Section 211 of the Superfund Amendments and Reauthorization Act of 1986 (SARA). A part of the DERP provides for the cleanup of hazardous substances associated with past Department of Defense (DoD) activities and is consistent with the provisions of the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA). It is the Air Force Installation Restoration Program (IRP)more » that has responsibility for the cleanup activities associated with CERCLA. Under contract to the Air Force Center for Environmental Excellence (AFCEE), the ECC Project Team, that included ECC, Cabrera Services, and Malcolm Pirnie, was responsible for the implementation of the actions at three sites. The three IRP (91b) sites included RW015, a 0.02 square kilometer (5.5 acre) site, RW017 a 0.003 square kilometer (0.9 acre) site, and RW033 an 0.356 square kilometer (88 acre) site. Adding to the complexities of the project were issues of archaeological areas of interest, jurisdictional wetlands, land open to hunting, issues of security as well as compliance to the myriad of air force base rules, regulations, and Air Force Instructions (AFI). The award of the project task order was July of 2005, the project plan phase started in July of 2005 followed by the remedy implementation that included characterization and remediation as required reached completion in June of 2006. The project closure including the development and approval final status survey reports, proposed plans, and decision documents that parallel the CERCLA process was initiated in June of 2006 and is expected to reach completion in August of 2007. This paper will focus on the issues of working to achieve radiological and chemical closure under a performance based contract vehicle and the challenges encountered while reaching this goal. (authors)« less

Accuracy of recorded tumor, node, and metastasis stage in a comprehensive cancer center.

PubMed

Brierley, James D; Catton, Pamela A; O'Sullivan, Brian; Dancey, Janet E; Dowling, Anthony J; Irish, Jonathan C; McGowan, Thomas S; Sturgeon, Jeremy F G; Swallow, Carol J; Rodrigues, George B; Panzarella, Tony

2002-01-15

The benefits of recording the tumor, node, and metastasis (TNM) stages of cancer patients are well accepted, but little is known about how accurately this is performed. An audit was performed to determine the accuracy of recorded stage and to act as a baseline before the implementation of an education program. All new patient referrals to Princess Margaret Hospital between July 1 and August 31, 1997, were reviewed. An audit panel composed of five health record technicians (HRTs) and 10 doctors was assembled. Each auditor reviewed 10% of the health record. If there was a discrepancy between the stage in the health record and the auditor stage, then the final stage was determined by the audit committee. Analysis of the agreement between the health record, the physician auditor, the HRT auditor, and the final stage was performed. A total of 855 patients were referred with a new diagnosis of a malignancy for which there was a TNM stage system; 833 patients (97.4%) had a stage assigned. There was agreement between the health record stage and final stage in 80% (95% confidence interval [CI], 77% to 82%) of cases for clinical stage, compared with 90% (95% CI, 87% to 92%) for pathologic stage. Of the major site groups, lung was the least accurately recorded. The most common major discrepancies were due to the recording of X when a definite category could be assigned. This audit demonstrates the importance of staging and provides impetus to develop staging guidelines and education programs.

Molecular Mechanism of Processive 3' to 5' RNA Translocation in the Active Subunit of the RNA Exosome Complex.

PubMed

Vuković, Lela; Chipot, Christophe; Makino, Debora L; Conti, Elena; Schulten, Klaus

2016-03-30

Recent experimental studies revealed structural details of 3' to 5' degradation of RNA molecules, performed by the exosome complex. ssRNA is channeled through its multisubunit ring-like core into the active site tunnel of its key exonuclease subunit Rrp44, which acts both as an enzyme and a motor. Even in isolation, Rrp44 can pull and sequentially cleave RNA nucleotides, one at a time, without any external energy input and release a final 3-5 nucleotide long product. Using molecular dynamics simulations, we identify the main factors that control these processes. Our free energy calculations reveal that RNA transfer from solution into the active site of Rrp44 is highly favorable, but dependent on the length of the RNA strand. While RNA strands formed by 5 nucleotides or more correspond to a decreasing free energy along the translocation coordinate toward the cleavage site, a 4-nucleotide RNA experiences a free energy barrier along the same direction, potentially leading to incomplete cleavage of ssRNA and the release of short (3-5) nucleotide products. We provide new insight into how Rrp44 catalyzes a localized enzymatic reaction and performs an action distributed over several RNA nucleotides, leading eventually to the translocation of whole RNA segments into the position suitable for cleavage.

Electronic Out-fall Inspection Application - 12007

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weymouth, A Kent III; Pham, Minh; Messick, Chuck

2012-07-01

In early 2009 an exciting opportunity was presented to the Geographic Information Systems (GIS) team at the Savannah River Site (SRS). The SRS maintenance group was directed to maintain all Out-falls on Site, increasing their workload from 75 to 183 out-falls with no additional resources. The existing out-fall inspection system consisted of inspections performed manually and documented via paper trail. The inspections were closed out upon completion of activities and placed in file cabinets with no central location for tracking/trending maintenance activities. A platform for meeting new improvements required for documentation by the Department of Health and Environmental Control (DHEC)more » out-fall permits was needed to replace this current system that had been in place since the 1980's. This was accomplished by building a geographically aware electronic application that improved reliability of site out-fall maintenance and ensured consistent standards were maintained for environmental excellence and worker efficiency. Inspections are now performed via tablet and uploaded to a central point. Work orders are completed and closed either in the field using tablets (mobile application) or in their offices (via web portal) using PCs. And finally completed work orders are now stored in a central database allowing trending of maintenance activities. (authors)« less

Environmental Survey preliminary report, Kansas City Plant, Kansas City, Missouri

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-01-01

This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE), Kansas City Plant (KCP), conducted March 23 through April 3, 1987. The Survey is being conducted by a multidisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team members are outside experts being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with the KCP. The Survey covers all environmental media and all areasmore » of environmental regulations. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data observations of the operations performed at the KCP, and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing certain environmental problems identified during its on-site activities. The Sampling and Analysis Plan is being executed by DOE's Argonne National Laboratory. When completed, the results will be incorporated into the KCP Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the KCP Survey. 94 refs., 39 figs., 55 tabs.« less

The Multi-site All-Sky CAmeRA (MASCARA). Finding transiting exoplanets around bright (mV < 8) stars

NASA Astrophysics Data System (ADS)

Talens, G. J. J.; Spronck, J. F. P.; Lesage, A.-L.; Otten, G. P. P. L.; Stuik, R.; Pollacco, D.; Snellen, I. A. G.

2017-05-01

This paper describes the design, operations, and performance of the Multi-site All-Sky CAmeRA (MASCARA). Its primary goal is to find new exoplanets transiting bright stars, 4 < mV < 8, by monitoring the full sky. MASCARA consists of one northern station on La Palma, Canary Islands (fully operational since February 2015), one southern station at La Silla Observatory, Chile (operational from early 2017), and a data centre at Leiden Observatory in the Netherlands. Both MASCARA stations are equipped with five interline CCD cameras using wide field lenses (24 mm focal length) with fixed pointings, which together provide coverage down to airmass 3 of the local sky. The interline CCD cameras allow for back-to-back exposures, taken at fixed sidereal times with exposure times of 6.4 sidereal seconds. The exposures are short enough that the motion of stars across the CCD does not exceed one pixel during an integration. Astrometry and photometry are performed on-site, after which the resulting light curves are transferred to Leiden for further analysis. The final MASCARA archive will contain light curves for 70 000 stars down to mV = 8.4, with a precision of 1.5% per 5 minutes at mV = 8.

Data Homogenization of the NOAA Long-Term Ozonesonde Records

NASA Astrophysics Data System (ADS)

Johnson, B.; Cullis, P.; Sterling, C. W.; Jordan, A. F.; Hall, E. G.; Petropavlovskikh, I. V.; Oltmans, S. J.; Mcconville, G.

2015-12-01

The NOAA long term balloon-borne ozonesonde sites at Boulder, Colorado; Hilo, Hawaii; and South Pole Station, Antarctica have measured weekly ozone profiles for more than 3 decades. The ozonesonde consists of an electrochemical concentration cell (ECC) sensor interfaced with a weather radiosonde which transmits high resolution ozone and meteorological data during ascent from the surface to 30-35 km altitude. During this 30 year time period there have been several model changes in the commercially available ECC ozonesondes and radiosondes as well as three adjustments in the ozone sensor solution composition at NOAA. These changes were aimed at optimizing the ozonesonde performance. Organized intercomparison campaigns conducted at the environmental simulation facility at the Research Centre Juelich, Germany and international field site testing have been the primary process for assessing new designs, instruments, or sensor solution changes and developing standard operating procedures. NOAA has also performed in-house laboratory tests and launched 28 dual ozonesondes at various sites since 1994 to provide further comparison data to determine the optimum homogenized data set. The final homogenization effort involved reviewing and editing several thousand individual ozonesonde profiles followed by applying the optimum correction algorithms for changes in type of sensor solution composition. The results of improved data sets will be shown with long term trends and uncertainties at various altitude levels.

75 FR 26131 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-11

... publishing a direct final Notice of Deletion of the Asbestos Dump Superfund Site (Site), located in Long Hill... Deletion of the Asbestos Dump Superfund site (Site), from the National Priorities List (NPL). The NPL... discusses the Asbestos Dump Superfund Site and demonstrates how it meets the deletion criteria. Section V...

Report of sampling and analysis results, Addison Army housing units, Addison, Illinois. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-09-01

The objectives of this sampling and analysis effort include further characterization of environmental contamination identified in an enhanced preliminary assessment carried out in 1989. The specific activities performed at this site were identification, evaluation of the condition, and collection of samples from specific suspected asbestos-containing materials, including floor tiles, pipe run and pipe fitting insulation, dust in the ductwork, and exterior siding, where present. These evaluation were necessary to clarify potential environmental issues identified in the earlier report, prior to the sale or realignment of the property.

Geothermal well site restoration and plug and abandonment of wells, DOE Gladys McCall test site, Cameron Parish, Louisiana and DOE Willis Hulin test site, Vermillion Parish, Louisiana

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rinehart, Ben N.

1994-08-01

A report is presented on the final phase of an energy research program conducted by the U.S. Department of Energy (DOE) involving two geothermal well sites in the State of Louisiana--the Gladys McCall site and the Willis Hulin site. The research program was intended to improve geothermal technology and to determine the efficacy of producing electricity commercially from geopressured resource sites. The final phase of the program consisted of plug and abandonment (P&A) of the wells and restoration of the well sites. Restoration involved (a) initial soil and water sampling and analysis; (b) removal and disposal of well pads, concrete,more » utility poles, and trash; (c) plugging of monitor and freshwater wells; and (d) site leveling and general cleanup. Restoration of the McCall site required removal of naturally occurring radioactive material (NORM), which was costly and time-consuming. Exhibits are included that provide copies of work permits and authorizations, P&A reports, and cost and salvage reports. Site locations, grid maps, and photographs are provided.« less

Final Data Report: P- and S-Wave Velocity Logging Borings C4993, C4996, and C4997 Part A: Interval Logs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steller, Robert; Diehl, John

2007-02-01

Insitu borehole P- and S-wave velocity measurements were collected in three borings located within the Waste Treatment Plant (WTP) boundaries at the Hanford Site, southeastern Washington. Geophysical data acquisition was performed between August and October of 2006 by Rob Steller, Charles Carter, Antony Martin and John Diehl of GEOVision. Data analysis was performed by Rob Steller and John Diehl, and reviewed by Antony Martin of GEOVision, and report preparation was performed by John Diehl and reviewed by Rob Steller. The work was performed under subcontract with Battelle, Pacific Northwest Division with Marty Gardner as Battelle’s Technical Representative and Alan Rohaymore » serving as the Technical Administrator for Pacific Northwest National Laboratory (PNNL). This report describes the field measurements, data analysis, and results of this work.« less

Final Data Report: P- and S-Wave Velocity Logging Borings C4993, C4996, and C4997 Part B: Overall Logs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Diehl, John; Steller, Robert

2007-03-20

Insitu borehole P- and S-wave velocity measurements were collected in three borings located within the Waste Treatment Plant (WTP) boundaries at the Hanford Site, southeastern Washington. Geophysical data acquisition was performed between August and October of 2006 by Rob Steller, Charles Carter, Antony Martin and John Diehl of GEOVision. Data analysis was performed by Rob Steller and John Diehl, and reviewed by Antony Martin of GEOVision, and report preparation was performed by John Diehl and reviewed by Rob Steller. The work was performed under subcontract with Battelle, Pacific Northwest Division with Marty Gardner as Battelle’s Technical Representative and Alan Rohaymore » serving as the Technical Administrator for Pacific Northwest National Laboratory (PNNL). This report describes the field measurements, data analysis, and results of this work.« less

Final Phase Flight Performance and Touchdown Time Assessment of TDV in RLV-TD HEX-01 Mission

NASA Astrophysics Data System (ADS)

Yadav, Sandeep; Jayakumar, M.; Nizin, Aziya; Kesavabrahmaji, K.; Shyam Mohan, N.

2017-12-01

RLV-TD HEX-01 mission was configured as a precursor flight to actual two stages to orbit vehicle. In this mission RLV-TD was designed as a two stage vehicle for demonstrating the hypersonic flight of a winged body vehicle at Mach No. 5. One of the main objectives of this mission was to generate data for better understanding of new technologies required to design the future vehicle. In this mission, the RLV-TD vehicle was heavily instrumented to get data related to performance of different subsystems. As per the mission design, RLV-TD will land in sea after flight duration of 700 s and travelling a distance of nearly 500 km in Bay of Bengal from the launch site for a nominal trajectory. The visibility studies for telemetry data of vehicle for the nominal and off nominal trajectories were carried out. Based on that, three ground stations were proposed for the telemetry data reception (including one in sea). Even with this scheme it was seen that during the final phase of the flight there will not be any ground station visible to the flight due to low elevation. To have the mission critical data during final phase of the flight, telemetry through INSAT scheme was introduced. During the end of the mission RLV-TD will be landing in the sea on a hypothetical runway. To know the exact time of touchdown for the flight in sea, there was no direct measurement available. Simultaneously there were all chances of losing ground station visibility just before touchdown, making it difficult to assess flight performance during that phase. In this work, telemetry and instrumentation scheme of RLV-TD HEX-01 mission is discussed with an objective to determine the flight performance during the final phase. Further, using various flight sensor data the touchdown time of TDV is assessed for this mission.

Four Finalist Landing Site Candidates for Mars Science Laboratory

NASA Image and Video Library

2008-11-19

Out of more than 30 sites considered as possible landing targets for NASA Mars Science Laboratory mission, by November 2008 four of the most intriguing places on Mars rose to the final round of the site-selection process.

Site selection for MSFC operational tests of solar heating and cooling systems

NASA Technical Reports Server (NTRS)

1978-01-01

The criteria, methodology, and sequence aspects of the site selection process are presented. This report organized the logical thought process that should be applied to the site selection process, but final decisions are highly selective.

Effect of the sequence data deluge on the performance of methods for detecting protein functional residues.

PubMed

Garrido-Martín, Diego; Pazos, Florencio

2018-02-27

The exponential accumulation of new sequences in public databases is expected to improve the performance of all the approaches for predicting protein structural and functional features. Nevertheless, this was never assessed or quantified for some widely used methodologies, such as those aimed at detecting functional sites and functional subfamilies in protein multiple sequence alignments. Using raw protein sequences as only input, these approaches can detect fully conserved positions, as well as those with a family-dependent conservation pattern. Both types of residues are routinely used as predictors of functional sites and, consequently, understanding how the sequence content of the databases affects them is relevant and timely. In this work we evaluate how the growth and change with time in the content of sequence databases affect five sequence-based approaches for detecting functional sites and subfamilies. We do that by recreating historical versions of the multiple sequence alignments that would have been obtained in the past based on the database contents at different time points, covering a period of 20 years. Applying the methods to these historical alignments allows quantifying the temporal variation in their performance. Our results show that the number of families to which these methods can be applied sharply increases with time, while their ability to detect potentially functional residues remains almost constant. These results are informative for the methods' developers and final users, and may have implications in the design of new sequencing initiatives.

A study of the stress wave factor technique for the characterization of composite materials

NASA Technical Reports Server (NTRS)

Henneke, E. G., II; Duke, J. C., Jr.; Stinchcomb, W. W.; Govada, A.; Lemascon, A.

1983-01-01

A testing program was undertaken to provide an independent investigation and evaluation of the stress wave factor for characterizing the mechanical behavior of composite laminates. Some of the data which was obtained after performing a very large number of tests to determine the reproducibility of the SWF measurement is presented. It was determined that, with some optimizing of experimental parameters, the SWF value can be reproduced to within + or - 10%. Results are also given which show that, after careful calibration procedures, the lowest SWF value along the length of a specimen will correlate very closely to the site of final failure when the specimen is loaded in tension. Finally, using a moire interferometry technique, it was found that local regions having the highest in plane strains under tensile loading also had the lowest SWF values.

Analysis of socket preservation using polylactide and polyglycolide (PLA-PGA) sponge: a clinical, radiographic, and histologic study.

PubMed

Madan, Rohit; Mohan, Ranjana; Bains, Vivek K; Gupta, Vivek; Singh, G P; Madan, Mani

2014-01-01

The aim of this study was to evaluate the extraction socket healing and dimensional changes following alveolar ridge preservation using polylactide and polyglycolide (PLA-PGA) sponge. Fifteen patients were selected for alveolar socket preservation immediately following tooth extraction. Monoradicular maxillary and mandibular teeth were evaluated. The selected sockets had intact sockets walls with a minimum of 7 mm of residual alveolar bone height. The test sites were thoroughly debrided and grafted with PLA-PGA sponge, while the control sites underwent natural healing. Computed tomography (CT) measurements were taken at baseline and 6 months. After 6 months of healing, final CT measurements were performed, and trephine core biopsy specimens were obtained for histologic analysis. Implants were placed immediately after biopsy harvesting. All subjects completed the study, and all sites healed without adverse events and allowed for implant placement. The mean difference in socket height, width, and density after 6 months was statistically significantly higher in the test sites compared with control sites. Clinical measurement at the midbuccal site of the alveolar socket showed a mean loss of 2.45 ± 0.67 mm in the control group, compared with a mean gain of 1.28 ± 0.58 mm in the test group. All test sites showed minimal ridge alterations, and statistically significant differences were observed between the test and control sites with respect to bone composition and horizontal and vertical bone loss, indicating that PLA-PGA sponge is suitable for alveolar ridge preservation.

Chemical Decontamination at Browns Ferry Unit 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hartwig, Ed; Reid, Richard

2003-09-01

In May, 2002, the Tennessee Valley Authority's (TVA) Board of Directors approved the recovery and restart of Unit 1 at Browns Ferry Nuclear Station. As an initial step in the site characterization and restart feasibility review, a majority of the primary reactor circuit was chemically decontaminated. Close cooperation between TVA and vendor personnel resulted in project completion ahead of schedule with outstanding results. The final average decontamination factors were excellent, and the final dose rates were very low, with contact readings on most points between one and three mRem/hr. In addition to allowing TVA to do a complete and thoroughmore » job of determining the feasibility of the Unit 1 restart, the decontamination effort will greatly reduce personnel exposure during plant recovery, both whole body exposure to gamma radiation and airborne exposure during pipe replacement efforts. The implementation of lessons learned from previous decontamination work performed at Browns Ferry, as well as decontamination efforts at other plants aided greatly in the success. Specific items of note are: (1) The initial leak check of the temporary decontamination system should include ancillary systems such as the spent resin system, as well as the main circulation loop. This could save time and dose exposure if leaks are discovered before the use of such systems is required. (2) Due to the quick turnaround time from the award of contract, a vendor representative was onsite early in the project to help with engineering efforts and procedures. This aided greatly in completing preparations for the decontamination. (3) The work was performed under a single maintenance activity. This resulted in great craft and plant support. (4) The constant coverage by the site's decontamination flush directors provided timely plant support and interface. (5) The FPC system isolation and back flushing to prevent residual chemicals from being left in the FPC system should have been addressed in more detail in the pre-engineering study to prevent delays during the final system cleanup.« less

Choosing a Field: How Graduate Student Choices of Field Sites Reflect Different Ideas of "Real" Anthropology in Colombia and the United States

ERIC Educational Resources Information Center

Macia, Laura

2012-01-01

This paper examines the decisions and motivations of graduate students in cultural anthropology when defining the field sites and topics of their final projects. The decisions among students at the Universidad de los Andes in Colombia are contrasted with those at the University of Pittsburgh in the United States. A review of recent final projects…

Remedial Investigation Report Area of Contamination (AOC) 43G. Volume 1

DTIC Science & Technology

1996-02-01

FORT DEVENS FINAL REMEDIAL INVESTIGATION FOR GROUP 2 & 7 SITES FINAL REMEDIAL INVESTIGATION REPORT AREA OF CONTAMINATION ( AOC ) 43G VOLUME I OF II...Liability Act for environmental investigations and remedial actions at Fort Devens . The agreement required that Site Investigations be undertaken at each... Remedial Investigation (RI) Report on Area of Contamination ( AOC ) 43G at the Fort Devens U.S. Army Installation, Massachusetts (

Enhanced Time Out: An Improved Communication Process.

PubMed

Nelson, Patricia E

2017-06-01

An enhanced time out is an improved communication process initiated to prevent such surgical errors as wrong-site, wrong-procedure, or wrong-patient surgery. The enhanced time out at my facility mandates participation from all members of the surgical team and requires designated members to respond to specified time out elements on the surgical safety checklist. The enhanced time out incorporated at my facility expands upon the safety measures from the World Health Organization's surgical safety checklist and ensures that all personnel involved in a surgical intervention perform a final check of relevant information. Initiating the enhanced time out at my facility was intended to improve communication and teamwork among surgical team members and provide a highly reliable safety process to prevent wrong-site, wrong-procedure, and wrong-patient surgery. Copyright © 2017 AORN, Inc. Published by Elsevier Inc. All rights reserved.

Facility Decontamination and Decommissioning Program Surveillance and Maintenance Plan, Revision 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Poderis, Reed J.; King, Rebecca A.

This Surveillance and Maintenance (S&M) Plan describes the activities performed between deactivation and final decommissioning of the following facilities located on the Nevada National Security Site, as documented in the Federal Facility Agreement and Consent Order under the Industrial Sites program as decontamination and decommissioning sites: ? Engine Maintenance, Assembly, and Disassembly (EMAD) Facility: o EMAD Building (Building 25-3900) o Locomotive Storage Shed (Building 25-3901) ? Test Cell C (TCC) Facility: o Equipment Building (Building 25-3220) o Motor Drive Building (Building 25-3230) o Pump Shop (Building 25-3231) o Cryogenic Lab (Building 25-3232) o Ancillary Structures (e.g., dewars, water tower, piping,more » tanks) These facilities have been declared excess and are in various stages of deactivation (low-risk, long-term stewardship disposition state). This S&M Plan establishes and implements a solid, cost-effective, and balanced S&M program consistent with federal, state, and regulatory requirements. A graded approach is used to plan and conduct S&M activities. The goal is to maintain the facilities in a safe condition in a cost-effective manner until their final end state is achieved. This plan accomplishes the following: ? Establishes S&M objectives and framework ? Identifies programmatic guidance for S&M activities to be conducted by National Security Technologies, LLC, for the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office (NNSA/NFO) ? Provides present facility condition information and identifies hazards ? Identifies facility-specific S&M activities to be performed and their frequency ? Identifies regulatory drivers, NNSA/NFO policies and procedures, and best management practices that necessitate implementation of S&M activities ? Provides criteria and frequencies for revisions and updates ? Establishes the process for identifying and dispositioning a condition that has not been previously identified or documented ? Provides instructions for implementing annual S&M inspections and activities The following facilities that were included in Revision 1 of this plan have reached final disposition and are no longer in the S&M program: ? Reactor Maintenance, Assembly, and Disassembly Facility, Building 25-3110 ? Test Cell A Facility, Building 25-3113 ? TCC Facility, Building 25-3210 ? Pluto Disassembly Facility, Building 26-2201 ? Super Kukla Facility, Building 27-5400« less

Argonne National Laboratory Expedited Site Characterization: First International Symposium on Integrated Technical Approaches to Site Characterization - Proceedings Volume

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-06-08

Laboratory applications for the analysis of PCBS (polychlorinated biphenyls) in environmental matrices such as soil/sediment/sludge and oil/waste oil were evaluated for potential reduction in waste, source reduction, and alternative techniques for final determination. As a consequence, new procedures were studied for solvent substitution, miniaturization of extraction and cleanups, minimization of reagent consumption, reduction of cost per analysis, and reduction of time. These new procedures provide adequate data that meet all the performance requirements for the determination of PCBS. Use of the new procedures reduced costs for all sample preparation techniques. Time and cost were also reduced by combining the newmore » sample preparation procedures with the power of fast gas chromatography. Separation of Aroclor 1254 was achieved in less than 6 min by using DB-1 and SPB-608 columns. With the greatly shortened run times, reproducibility can be tested quickly and consequently with low cost. With performance-based methodology, the applications presented here can be applied now, without waiting for regulatory approval.« less

Equipment for fully homologous bulb turbine model testing in Laval University

NASA Astrophysics Data System (ADS)

R, Fraser; D, Vallée; Y, Jean; C, Deschênes

2014-03-01

Within the context of liberalisation of the energy market, hydroelectricity remains a first class source of clean and renewable energy. Combining the growing demand of energy, its increasing value and the appreciation associated to the sustainable development, low head sites formerly considered as non-profitable are now exploitable. Bulb turbines likely to equip such sites are traditionally developed on model using right angle transmission leading to piers enlargement for power take off shaft passage, thus restricting possibilities to have fully homologous hydraulic passages. Aiming to sustain good quality development on fully homologous scale model of bulb turbines, the Hydraulic Machines Laboratory (LAMH) of Laval University has developed a brake with an enhanced power to weight ratio. This powerful brake is small enough to be located in the bulb shell while dissipating power without mandatory test head reduction. This paper first presents the basic technology of this brake and its application. Then both its main performance capabilities and dimensional characteristics will be detailed. The instrumentation used to perform accurate measurements will be finally presented.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choi, Jae -Soon; Schwartz, Viviane; Santillan-Jimenez, Eduardo

In this paper, we investigated the structural evolution of molybdenum carbides subjected to hot aqueous environments and their catalytic performance in low-temperature hydroprocessing of acetic acid. While bulk structures of Mo carbides were maintained after aging in hot liquid water, a portion of carbidic Mo sites were converted to oxidic sites. Water aging also induced changes to the non-carbidic carbon deposited during carbide synthesis and increased surface roughness, which in turn affected carbide pore volume and surface area. The extent of these structural changes was sensitive to the initial carbide structure and was lower under actual hydroprocessing conditions indicating themore » possibility of further improving the hydrothermal stability of Mo carbides by optimizing catalyst structure and operating conditions. Mo carbides were active in acetic acid conversion in the presence of liquid water, their activity being comparable to that of Ru/C. Finally, the results suggest that effective and inexpensive bio-oil hydroprocessing catalysts could be designed based on Mo carbides, although a more detailed understanding of the structure-performance relationships is needed, especially in upgrading of more complex reaction mixtures or real bio-oils.« less

In situ observations of the isotopic composition of methane at the Cabauw tall tower site

NASA Astrophysics Data System (ADS)

Röckmann, Thomas; Eyer, Simon; van der Veen, Carina; Popa, Maria E.; Tuzson, Béla; Monteil, Guillaume; Houweling, Sander; Harris, Eliza; Brunner, Dominik; Fischer, Hubertus; Zazzeri, Giulia; Lowry, David; Nisbet, Euan G.; Brand, Willi A.; Necki, Jaroslav M.; Emmenegger, Lukas; Mohn, Joachim

2016-08-01

High-precision analyses of the isotopic composition of methane in ambient air can potentially be used to discriminate between different source categories. Due to the complexity of isotope ratio measurements, such analyses have generally been performed in the laboratory on air samples collected in the field. This poses a limitation on the temporal resolution at which the isotopic composition can be monitored with reasonable logistical effort. Here we present the performance of a dual isotope ratio mass spectrometric system (IRMS) and a quantum cascade laser absorption spectroscopy (QCLAS)-based technique for in situ analysis of the isotopic composition of methane under field conditions. Both systems were deployed at the Cabauw Experimental Site for Atmospheric Research (CESAR) in the Netherlands and performed in situ, high-frequency (approx. hourly) measurements for a period of more than 5 months. The IRMS and QCLAS instruments were in excellent agreement with a slight systematic offset of (+0.25 ± 0.04) ‰ for δ13C and (-4.3 ± 0.4) ‰ for δD. This was corrected for, yielding a combined dataset with more than 2500 measurements of both δ13C and δD. The high-precision and high-temporal-resolution dataset not only reveals the overwhelming contribution of isotopically depleted agricultural CH4 emissions from ruminants at the Cabauw site but also allows the identification of specific events with elevated contributions from more enriched sources such as natural gas and landfills. The final dataset was compared to model calculations using the global model TM5 and the mesoscale model FLEXPART-COSMO. The results of both models agree better with the measurements when the TNO-MACC emission inventory is used in the models than when the EDGAR inventory is used. This suggests that high-resolution isotope measurements have the potential to further constrain the methane budget when they are performed at multiple sites that are representative for the entire European domain.

In-situ observations of the isotopic composition of methane at the Cabauw tall tower site

NASA Astrophysics Data System (ADS)

Röckmann, Thomas; Eyer, Simon; van der Veen, Carina; E Popa, Maria; Tuzson, Béla; Monteil, Guillaume; Houweling, Sander; Harris, Eliza; Brunner, Dominik; Fischer, Hubertus; Zazzeri, Giulia; Lowry, David; Nisbet, Euan G.; Brand, Willi A.; Necki, Jaroslav M.; Emmenegger, Lukas; Mohn, Joachim

2017-04-01

High precision analyses of the isotopic composition of methane in ambient air can potentially be used to discriminate between different source categories. Due to the complexity of isotope ratio measurements, such analyses have generally been performed in the laboratory on air samples collected in the field. This poses a limitation on the temporal resolution at which the isotopic composition can be monitored with reasonable logistical effort. Here we present the performance of a dual isotope ratio mass spectrometric system (IRMS) and a quantum cascade laser absorption spectroscopy (QCLAS) based technique for in-situ analysis of the isotopic composition of methane under field conditions. Both systems were deployed at the Cabauw experimental site for atmospheric research (CESAR) in the Netherlands and performed in-situ, high-frequency (approx. hourly) measurements for a period of more than 5 months. The IRMS and QCLAS instruments were in excellent agreement with a slight systematic offset of +0.05 ± 0.03 ‰ for δ13C-CH4 and -3.6 ± 0.4 ‰ for δD-CH4. This was corrected for, yielding a combined dataset with more than 2500 measurements of both δ13C and δD. The high precision and temporal resolution dataset does not only reveal the overwhelming contribution of isotopically depleted agricultural CH4 emissions from ruminants at the Cabauw site, but also allows the identification of specific events with elevated contributions from more enriched sources such as natural gas and landfills. The final dataset was compared to model calculations using the global model TM5 and the mesoscale model FLEXPART-COSMO. The results of both models agree better with the measurements when the TNO-MACC emission inventory is used in the models than when the EDGAR inventory is used. This suggests that high-resolution isotope measurements have the potential to further constrain the methane budget, when they are performed at multiple sites that are representative for the entire European domain.

Two-dimensional assembly structure of graphene and TiO2 nanosheets from titanic acid with enhanced visible-light photocatalytic performance

NASA Astrophysics Data System (ADS)

Hao, Rong; Guo, Shien; Wang, Xiuwen; Feng, Tong; Feng, Qingmao; Li, Mingxia; Jiang, Baojiang

2016-06-01

The titanic acid sheets were prepared by one-step hydrazine hydrate-assisted hydrothermal process. Then the reduced graphite oxide (rGO)@TiO2 nanosheet composites were finally obtained through ultrasonic exfoliation and following calcination treatment process. rGO@TiO2 nanosheet composites show excellent hydrogen production performance under AM1.5 light source. The highest hydrogen evolution yield (923.23 μmol) is nearly two times higher than that of pure TiO2, mainly due to the special electron structure and more active sites for TiO2 nanosheet. The introduction of graphene could improve the TiO2 nanosheet stability and extend visible-light absorption range.

Energy efficiency in membrane bioreactors.

PubMed

Barillon, B; Martin Ruel, S; Langlais, C; Lazarova, V

2013-01-01

Energy consumption remains the key factor for the optimisation of the performance of membrane bioreactors (MBRs). This paper presents the results of the detailed energy audits of six full-scale MBRs operated by Suez Environnement in France, Spain and the USA based on on-site energy measurement and analysis of plant operation parameters and treatment performance. Specific energy consumption is compared for two different MBR configurations (flat sheet and hollow fibre membranes) and for plants with different design, loads and operation parameters. The aim of this project was to understand how the energy is consumed in MBR facilities and under which operating conditions, in order to finally provide guidelines and recommended practices for optimisation of MBR operation and design to reduce energy consumption and environmental impacts.

Science plus management equals successful remediation: A case study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buehlman, M.D.; Rogers, D.T.; Payne, F.C.

A case study involving a Brownfields site in southeastern Michigan clearly illustrates the elements of successful remediation. The site`s soil was contaminated with polychlorinated biphenyls (PCBs) and its groundwater with a variety of chlorinated solvents. The original estimate for remediation has exceeded $30 million. Several phases of investigation were conducted to evaluate the nature and sources of contaminants, the site`s hydrogeology, potential risks to human health and the environment, and feasible remedial technologies. Multiple cleanup criteria were established for different affected areas based on the results of the investigations, changes that were taking place with the state cleanup regulations andmore » standards and subsequent negotiations with state and federal regulators. Innovative remedial technologies were selected. The result was a remediation that met or exceeded all soil and groundwater cleanup objectives, was performed on schedule, and was highly cost-effective. The final cost was limited to $3 million--one-tenth of the original estimate. The success of this project involved meticulous scientific study and comprehensive understanding of applicable regulatory requirements and available remediation technologies. It also required effective project management to coordinate the multidisciplinary efforts involved and to maintain the constant vertical and horizontal communications necessary to ensure sound decisions at every step in the process.« less

Core Binding Site of a Thioflavin-T-Derived Imaging Probe on Amyloid β Fibrils Predicted by Computational Methods.

PubMed

Kawai, Ryoko; Araki, Mitsugu; Yoshimura, Masashi; Kamiya, Narutoshi; Ono, Masahiro; Saji, Hideo; Okuno, Yasushi

2018-05-16

Development of new diagnostic imaging probes for Alzheimer's disease, such as positron emission tomography (PET) and single photon emission computed tomography (SPECT) probes, has been strongly desired. In this study, we investigated the most accessible amyloid β (Aβ) binding site of [ 123 I]IMPY, a Thioflavin-T-derived SPECT probe, using experimental and computational methods. First, we performed a competitive inhibition assay with Orange-G, which recognizes the KLVFFA region in Aβ fibrils, suggesting that IMPY and Orange-G bind to different sites in Aβ fibrils. Next, we precisely predicted the IMPY binding site on a multiple-protofilament Aβ fibril model using computational approaches, consisting of molecular dynamics and docking simulations. We generated possible IMPY-binding structures using docking simulations to identify candidates for probe-binding sites. The binding free energy of IMPY with the Aβ fibril was calculated by a free energy simulation method, MP-CAFEE. These computational results suggest that IMPY preferentially binds to an interfacial pocket located between two protofilaments and is stabilized mainly through hydrophobic interactions. Finally, our computational approach was validated by comparing it with the experimental results. The present study demonstrates the possibility of computational approaches to screen new PET/SPECT probes for Aβ imaging.

Evaluating Conceptual Site Models with Multicomponent Reactive Transport Modeling

NASA Astrophysics Data System (ADS)

Dai, Z.; Heffner, D.; Price, V.; Temples, T. J.; Nicholson, T. J.

2005-05-01

Modeling ground-water flow and multicomponent reactive chemical transport is a useful approach for testing conceptual site models and assessing the design of monitoring networks. A graded approach with three conceptual site models is presented here with a field case of tetrachloroethene (PCE) transport and biodegradation near Charleston, SC. The first model assumed a one-layer homogeneous aquifer structure with semi-infinite boundary conditions, in which an analytical solution of the reactive solute transport can be obtained with BIOCHLOR (Aziz et al., 1999). Due to the over-simplification of the aquifer structure, this simulation cannot reproduce the monitoring data. In the second approach we used GMS to develop the conceptual site model, a layer-cake multi-aquifer system, and applied a numerical module (MODFLOW and RT3D within GMS) to solve the flow and reactive transport problem. The results were better than the first approach but still did not fit the plume well because the geological structures were still inadequately defined. In the third approach we developed a complex conceptual site model by interpreting log and seismic survey data with Petra and PetraSeis. We detected a major channel and a younger channel, through the PCE source area. These channels control the local ground-water flow direction and provide a preferential chemical transport pathway. Results using the third conceptual site model agree well with the monitoring concentration data. This study confirms that the bias and uncertainty from inadequate conceptual models are much larger than those introduced from an inadequate choice of model parameter values (Neuman and Wierenga, 2003; Meyer et al., 2004). Numerical modeling in this case provides key insight into the hydrogeology and geochemistry of the field site for predicting contaminant transport in the future. Finally, critical monitoring points and performance indicator parameters are selected for future monitoring to confirm system performance.

SU-D-213-05: Design, Evaluation and First Applications of a Off-Site State-Of-The-Art 3D Dosimetry System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malcolm, J; Mein, S; McNiven, A

2015-06-15

Purpose: To design, construct and commission a prototype in-house three dimensional (3D) dose verification system for stereotatic body radiotherapy (SBRT) verification at an off-site partner institution. To investigate the potential of this system to achieve sufficient performance (1mm resolution, 3% noise, within 3% of true dose reading) for SBRT verification. Methods: The system was designed utilizing a parallel ray geometry instigated by precision telecentric lenses and an LED 630nm light source. Using a radiochromic dosimeter, a 3D dosimetric comparison with our gold-standard system and treatment planning software (Eclipse) was done for a four-field box treatment, under gamma passing criteria ofmore » 3%/3mm/10% dose threshold. Post off-site installation, deviations in the system’s dose readout performance was assessed by rescanning the four-field box irradiated dosimeter and using line-profiles to compare on-site and off-site mean and noise levels in four distinct dose regions. As a final step, an end-to-end test of the system was completed at the off-site location, including CT-simulation, irradiation of the dosimeter and a 3D dosimetric comparison of the planned (Pinnacle{sup 3}) to delivered dose for a spinal SBRT treatment(12 Gy per fraction). Results: The noise level in the high and medium dose regions of the four field box treatment was relatively 5% pre and post installation. This reflects the reduction in positional uncertainty through the new design. This At 1mm dose voxels, the gamma pass rates(3%,3mm) for our in-house gold standard system and the off-site system were comparable at 95.8% and 93.2% respectively. Conclusion: This work will describe the end-to-end process and results of designing, installing, and commissioning a state-of-the-art 3D dosimetry system created for verification of advanced radiation treatments including spinal radiosurgery.« less

Hydrologic evaluation methodology for estimating water movement through the unsaturated zone at commercial low-level radioactive waste disposal site

USGS Publications Warehouse

Meyer, P.D.; Rockhold, M.L.; Nichols, W.E.; Gee, G.W.

1996-01-01

This report identifies key technical issues related to hydrologic assessment of water flow in the unsaturated zone at low-level radioactive waste (LLW) disposal facilities. In addition, a methodology for incorporating these issues in the performance assessment of proposed LLW disposal facilities is identified and evaluated. The issues discussed fall into four areas:Estimating the water balance at a site (i.e., infiltration, runoff, water storage, evapotranspiration, and recharge);Analyzing the hydrologic performance of engineered components of a facility;Evaluating the application of models to the prediction of facility performance; andEstimating the uncertainty in predicted facility performance.An estimate of recharge at a LLW site is important since recharge is a principal factor in controlling the release of contaminants via the groundwater pathway. The most common methods for estimating recharge are discussed in Chapter 2. Many factors affect recharge; the natural recharge at an undisturbed site is not necessarily representative either of the recharge that will occur after the site has been disturbed or of the flow of water into a disposal facility at the site. Factors affecting recharge are discussed in Chapter 2.At many sites engineered components are required for a LLW facility to meet performance requirements. Chapter 3 discusses the use of engineered barriers to control the flow of water in a LLW facility, with a particular emphasis on cover systems. Design options and the potential performance and degradation mechanisms of engineered components are also discussed.Water flow in a LLW disposal facility must be evaluated before construction of the facility. In addition, hydrologic performance must be predicted over a very long time frame. For these reasons, the hydrologic evaluation relies on the use of predictive modeling. In Chapter 4, the evaluation of unsaturated water flow modeling is discussed. A checklist of items is presented to guide the evaluation. Several computer simulation codes that were used in the examples (Chapter 6) are discussed with respect to this checklist. The codes used include HELP, UNSAT-H, and VAM3DCG.To provide a defensible estimate of water flow in a LLW disposal facility, the uncertainty associated with model predictions must be considered. Uncertainty arises because of the highly heterogeneous nature of most subsurface environments and the long time frame required in the analysis. Sources of uncertainty in hydrologic evaluation of the unsaturated zone and several approaches for analysis are discussed in Chapter 5. The methods of analysis discussed include a bounding approach, sensitivity analysis, and Monte Carlo simulation.To illustrate the application of the discussion in Chapters 2 through 5, two examples are presented in Chapter 6. The first example is of a below ground vault located in a humid environment. The second example looks at a shallow land burial facility located in an arid environment. The examples utilize actual site-specific data and realistic facility designs. The two examples illustrate the issues unique to humid and arid sites as well as the issues common to all LLW sites. Strategies for addressing the analytical difficulties arising in any complex hydrologic evaluation of the unsaturated zone are demonstrated.The report concludes with some final observations and recommendations.

Investigation and demonstration of turbidity reduction in stormwater runoff for Oklahoma highway construction sites : final report.

DOT National Transportation Integrated Search

2013-12-01

The Environmental protection Agency (USEPA) has issued new requirements on the construction industry to control the discharge of pollutants from the sites. The construction effluent guidelines or ELGs require construction sites to reduce the pollu...

Contractor for geopressured-geothermal sites: Final contract report, Volume 1, fiscal years 1986--1990 (5 years), testing of wells through October 1990. Appendix A, Volume 2, Gladys McCall Site (Cameron Parish LA); Appendix B-1, Volume 3, Pleasant Bayou Site; Appendix B-2, Volume 4, Pleasant Bayou Site; Appendix C, Volume 5, Willis Hulin Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-09-01

Field tests and studies were conducted to determine the production behavior of geopressured-geothermal reservoirs and their potential as future energy sources. Results are presented for Gladys McCall Site, Pleasant Bayou Site, and Hulin Site.

Penetrator role in Mars sample strategy

NASA Technical Reports Server (NTRS)

Boynton, William; Dwornik, Steve; Eckstrom, William; Roalstad, David A.

1988-01-01

The application of the penetrator to a Mars Return Sample Mission (MRSM) has direct advantages to meet science objectives and mission safety. Based on engineering data and work currently conducted at Ball Aerospace Systems Division, the concept of penetrators as scientific instruments is entirely practical. The primary utilization of a penetrator for MRSM would be to optimize the selection of the sample site location and to help in selection of the actual sample to be returned to Earth. It is recognized that the amount of sample to be returned is very limited, therefore the selection of the sample site is critical to the success of the mission. The following mission scenario is proposed. The site selection of a sample to be acquired will be performed by science working groups. A decision will be reached and a set of target priorities established based on data to give geochemical, geophysical and geological information. The first task of a penetrator will be to collect data at up to 4 to 6 possible landing sites. The penetrator can include geophysical, geochemical, geological and engineering instruments to confirm that scientific data requirements at that site will be met. This in situ near real-time data, collected prior to final targeting of the lander, will insure that the sample site is both scientifically valuable and also that it is reachable within limits of the capability of the lander.

The spin-partitioned total position-spread tensor: An application to Heisenberg spin chains

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fertitta, Edoardo; Paulus, Beate; El Khatib, Muammar

2015-12-28

The spin partition of the Total Position-Spread (TPS) tensor has been performed for one-dimensional Heisenberg chains with open boundary conditions. Both the cases of a ferromagnetic (high-spin) and an anti-ferromagnetic (low-spin) ground-state have been considered. In the case of a low-spin ground-state, the use of alternating magnetic couplings allowed to investigate the effect of spin-pairing. The behavior of the spin-partitioned TPS (SP-TPS) tensor as a function of the number of sites turned to be closely related to the presence of an energy gap between the ground-state and the first excited-state at the thermodynamic limit. Indeed, a gapped energy spectrum ismore » associated to a linear growth of the SP-TPS tensor with the number of sites. On the other hand, in gapless situations, the spread presents a faster-than-linear growth, resulting in the divergence of its per-site value. Finally, for the case of a high-spin wave function, an analytical expression of the dependence of the SP-TPS on the number of sites n and the total spin-projection S{sub z} has been derived.« less

Continuous feed, on-site composting of kitchen garbage.

PubMed

Hwang, Eung-Ju; Shin, Hang-Sik; Tay, Joo-Hwa

2002-04-01

Kitchen garbage generated at a school cafeteria was treated and stabilised in a controlled on-site composting unit for volume reduction and on-site utilisation of processed garbage. The on-site composter was fed with the garbage on a daily basis during the two-months experimental period. Compost was not removed from the unit but was entirely reused as a bulking agent in order to minimise the need for additional bulking agent and compost handling. Performance of the composter tinder this condition was investigated. Most of the easily degradable organic matter (EDM) in the garbage was biodegraded rapidly, and the final product had a low content of EDM. Lipids, total sugar, and hemi-cellulose were degraded 96%, 81%, and 66% respectively. Free air space (FAS) was higher than 0.5 all the time, so accumulation of dry matter in the unit was not significant in reducing reaction efficiency. Other reaction parameters such as pH and MC were kept within a suitable range; however, it was advisable to maintain MC at over 46%. As a result, this method of operation was able to stabilise the garbage with low sawdust demand and little compost production.

Probabilistic Assessment of Above Zone Pressure Predictions at a Geologic Carbon Storage Site

PubMed Central

Namhata, Argha; Oladyshkin, Sergey; Dilmore, Robert M.; Zhang, Liwei; Nakles, David V.

2016-01-01

Carbon dioxide (CO2) storage into geological formations is regarded as an important mitigation strategy for anthropogenic CO2 emissions to the atmosphere. This study first simulates the leakage of CO2 and brine from a storage reservoir through the caprock. Then, we estimate the resulting pressure changes at the zone overlying the caprock also known as Above Zone Monitoring Interval (AZMI). A data-driven approach of arbitrary Polynomial Chaos (aPC) Expansion is then used to quantify the uncertainty in the above zone pressure prediction based on the uncertainties in different geologic parameters. Finally, a global sensitivity analysis is performed with Sobol indices based on the aPC technique to determine the relative importance of different parameters on pressure prediction. The results indicate that there can be uncertainty in pressure prediction locally around the leakage zones. The degree of such uncertainty in prediction depends on the quality of site specific information available for analysis. The scientific results from this study provide substantial insight that there is a need for site-specific data for efficient predictions of risks associated with storage activities. The presented approach can provide a basis of optimized pressure based monitoring network design at carbon storage sites. PMID:27996043

Probabilistic Assessment of Above Zone Pressure Predictions at a Geologic Carbon Storage Site

NASA Astrophysics Data System (ADS)

Namhata, Argha; Oladyshkin, Sergey; Dilmore, Robert M.; Zhang, Liwei; Nakles, David V.

2016-12-01

Carbon dioxide (CO2) storage into geological formations is regarded as an important mitigation strategy for anthropogenic CO2 emissions to the atmosphere. This study first simulates the leakage of CO2 and brine from a storage reservoir through the caprock. Then, we estimate the resulting pressure changes at the zone overlying the caprock also known as Above Zone Monitoring Interval (AZMI). A data-driven approach of arbitrary Polynomial Chaos (aPC) Expansion is then used to quantify the uncertainty in the above zone pressure prediction based on the uncertainties in different geologic parameters. Finally, a global sensitivity analysis is performed with Sobol indices based on the aPC technique to determine the relative importance of different parameters on pressure prediction. The results indicate that there can be uncertainty in pressure prediction locally around the leakage zones. The degree of such uncertainty in prediction depends on the quality of site specific information available for analysis. The scientific results from this study provide substantial insight that there is a need for site-specific data for efficient predictions of risks associated with storage activities. The presented approach can provide a basis of optimized pressure based monitoring network design at carbon storage sites.

Cultural Resources Literature Search and Records Review - Upper Mississippi River Basin. Volume 1. Introduction and Narrative

DTIC Science & Technology

1983-01-01

project area. The following summary taken from the final environmental impact statement prepared by the St. Paul District in 1974, serves well to...Archeologist 62 (2): 168-205. U.S. ARMY CORPS OF ENGINEERS 1974 Final Environmental Impact Statement: Operation and Maintenance, 9 Foot Navigation Channel...Spring Hollow Rock Shelter No. 2; Elephant Site; Waterville Rock Shelter; Jeffey Edwards Creek Rock Shelter; Pufahl Site, Allamakee County; Gingerstairs

Earthquake design criteria for small hydro projects in the Philippines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martin, P.P.; McCandless, D.H.; Asce, M.

1995-12-31

The definition of the seismic environment and seismic design criteria of more than twenty small hydro projects in the northern part of the island of Luzon in the Philippines took a special urgency on the wake of the Magnitude 7.7 earthquake that shook the island on July 17, 1990. The paper describes the approach followed to determine design shaking level criteria at each hydro site consistent with the seismic environment estimated at that same site. The approach consisted of three steps: (1) Seismicity: understanding the mechanisms and tectonic features susceptible to generate seismicity and estimating the associated seismicity levels, (2)more » Seismic Hazard: in the absence of an accurate historical record, using statistics to determine the expected level of ground shaking at a site during the operational 100-year design life of each Project, and (3) Criteria Selection: finally and most importantly, exercising judgment in estimating the final proposed level of shaking at each site. The resulting characteristics of estimated seismicity and seismic hazard and the proposed final earthquake design criteria are provided.« less

Final waste forms project: Performance criteria for phase I treatability studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gilliam, T.M.; Hutchins, D.A.; Chodak, P. III

1994-06-01

This document defines the product performance criteria to be used in Phase I of the Final Waste Forms Project. In Phase I, treatability studies will be performed to provide {open_quotes}proof-of-principle{close_quotes} data to establish the viability of stabilization/solidification (S/S) technologies. This information is required by March 1995. In Phase II, further treatability studies, some at the pilot scale, will be performed to provide sufficient data to allow treatment alternatives identified in Phase I to be more fully developed and evaluated, as well as to reduce performance uncertainties for those methods chosen to treat a specific waste. Three main factors influence themore » development and selection of an optimum waste form formulation and hence affect selection of performance criteria. These factors are regulatory, process-specific, and site-specific waste form standards or requirements. Clearly, the optimum waste form formulation will require consideration of performance criteria constraints from each of the three categories. Phase I will focus only on the regulatory criteria. These criteria may be considered the minimum criteria for an acceptable waste form. In other words, a S/S technology is considered viable only if it meet applicable regulatory criteria. The criteria to be utilized in the Phase I treatability studies were primarily taken from Environmental Protection Agency regulations addressed in 40 CFR 260 through 265 and 268; and Nuclear Regulatory Commission regulations addressed in 10 CFR 61. Thus the majority of the identified criteria are independent of waste form matrix composition (i.e., applicable to cement, glass, organic binders etc.).« less

Record of decision, Bomarc Missile Accident Site, Mcguire AFB, New Jersey. Final report, November 1989-May 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

West, G.

1992-11-20

This document presents the selected final remedial action for the radioactive wastes at the BOMARC Missile Site, McGuire Air Force Base, New Jersey. The BOMARC Missile Site became contaminated in 1960 as the result of a fire which partially consumed a nuclear warhead-equipped BOMARC missile. The Air Force has decided to pursue excavation and Off-site Disposal of contaminated waste at a Department of Energy (DOE) disposal facility. This is a cost effective, permanent remedy, and is the environmentally preferred alternative. However, should the Air Force be denied the use of a DOE facility, or if other events should dramatically decreasemore » the cost effectiveness of this remedy, then as an interim remedy, the Air Force will maintain the BOMARC Missile Site in accordance with the NEPA No Action Alternative.« less

EXECUTIVE SUMMARY OF STATE DATA RELATED TO ABANDONED CENTRALIZED AND COMMERCIAL DRILLING-FLUID DISPOSAL SITES IN LOUISIANA, NEW MEXICO, OKLAHOMA, AND TEXAS

DOE Office of Scientific and Technical Information (OSTI.GOV)

H. Seay Nance

2003-03-01

This 2003 Spring Semi-Annual Report contains a summary of the Final Technical Report being prepared for the Soil Remediation Requirements at Commercial and Centralized Drilling-Fluid Disposal (CCDD) Sites project funded by the United States Department of Energy under DOE Award No. DE-AC26-99BC15225. The summary describes (1) the objectives of the investigation, (2) a rationale and methodology of the investigation, (3) sources of data, assessment of data quality, and data availability, (4) examples of well documented centralized and commercial drilling-fluid disposal (CCDD) sites and other sites where drilling fluid was disposed of, and (5) examples of abandoned sites and measures undertakenmore » for their assessment and remediation. The report also includes most of the figures, tables, and appendices that will be included in the final report.« less

Construction of a Novel Three-Dimensional PEDOT/RVC Electrode Structure for Capacitive Deionization: Testing and Performance

PubMed Central

Rahaman, Mostafizur; Govindasami, Periyasami; Almoiqli, Mohammed; Altalhi, Tariq; Mezni, Amine

2017-01-01

This article discusses the deposition of different amount of microstuctured poly(3,4-ethylenedioxythiophene) (PEDOT) on reticulated vitreous carbon (RVC) by electrochemical method to prepare three-dimensional (3D) PEDOT/RVC electrodes aimed to be used in capacitive deionization (CDI) technology. A CDI unit cell has been constructed here in this study. The performance of CDI cell in the ion removal of NaCl onto the sites of PEDOT/RVC electrode has been systematically investigated in terms of flow-rate, applied electrical voltage, and increasing PEDOT loading on PEDOT/RVC electrodes. It is observed that the increase in flow-rate, electric voltage, and PEDOT loading up to a certain level improve the ion removal performance of electrode in the CDI cell. The result shows that these electrodes can be used effectively for desalination technology, as the electrosorption capacity/desalination performance of these electrodes is quite high compared to carbon materials. Moreover, the stability of the electrodes has been tested and it is reported that these electrodes are regenerative. The effect of increasing NaCl concentration on the electrosorption capacity has also been investigated for these electrodes. Finally, it has been shown that 1 m3 PEDOT-120 min/RVC electrodes from 75 mg/L NaCl feed solution produce 421, 978 L water per day of 20 mg/L NaCl final concentration. PMID:28773205

Construction of a Novel Three-Dimensional PEDOT/RVC Electrode Structure for Capacitive Deionization: Testing and Performance.

PubMed

Aldalbahi, Ali; Rahaman, Mostafizur; Govindasami, Periyasami; Almoiqli, Mohammed; Altalhi, Tariq; Mezni, Amine

2017-07-24

This article discusses the deposition of different amount of microstuctured poly(3,4-ethylenedioxythiophene) (PEDOT) on reticulated vitreous carbon (RVC) by electrochemical method to prepare three-dimensional (3D) PEDOT/RVC electrodes aimed to be used in capacitive deionization (CDI) technology. A CDI unit cell has been constructed here in this study. The performance of CDI cell in the ion removal of NaCl onto the sites of PEDOT/RVC electrode has been systematically investigated in terms of flow-rate, applied electrical voltage, and increasing PEDOT loading on PEDOT/RVC electrodes. It is observed that the increase in flow-rate, electric voltage, and PEDOT loading up to a certain level improve the ion removal performance of electrode in the CDI cell. The result shows that these electrodes can be used effectively for desalination technology, as the electrosorption capacity/desalination performance of these electrodes is quite high compared to carbon materials. Moreover, the stability of the electrodes has been tested and it is reported that these electrodes are regenerative. The effect of increasing NaCl concentration on the electrosorption capacity has also been investigated for these electrodes. Finally, it has been shown that 1 m³ PEDOT-120 min/RVC electrodes from 75 mg/L NaCl feed solution produce 421, 978 L water per day of 20 mg/L NaCl final concentration.

MDD-carb: a combinatorial model for the identification of protein carbonylation sites with substrate motifs.

PubMed

Kao, Hui-Ju; Weng, Shun-Long; Huang, Kai-Yao; Kaunang, Fergie Joanda; Hsu, Justin Bo-Kai; Huang, Chien-Hsun; Lee, Tzong-Yi

2017-12-21

Carbonylation, which takes place through oxidation of reactive oxygen species (ROS) on specific residues, is an irreversibly oxidative modification of proteins. It has been reported that the carbonylation is related to a number of metabolic or aging diseases including diabetes, chronic lung disease, Parkinson's disease, and Alzheimer's disease. Due to the lack of computational methods dedicated to exploring motif signatures of protein carbonylation sites, we were motivated to exploit an iterative statistical method to characterize and identify carbonylated sites with motif signatures. By manually curating experimental data from research articles, we obtained 332, 144, 135, and 140 verified substrate sites for K (lysine), R (arginine), T (threonine), and P (proline) residues, respectively, from 241 carbonylated proteins. In order to examine the informative attributes for classifying between carbonylated and non-carbonylated sites, multifarious features including composition of twenty amino acids (AAC), composition of amino acid pairs (AAPC), position-specific scoring matrix (PSSM), and positional weighted matrix (PWM) were investigated in this study. Additionally, in an attempt to explore the motif signatures of carbonylation sites, an iterative statistical method was adopted to detect statistically significant dependencies of amino acid compositions between specific positions around substrate sites. Profile hidden Markov model (HMM) was then utilized to train a predictive model from each motif signature. Moreover, based on the method of support vector machine (SVM), we adopted it to construct an integrative model by combining the values of bit scores obtained from profile HMMs. The combinatorial model could provide an enhanced performance with evenly predictive sensitivity and specificity in the evaluation of cross-validation and independent testing. This study provides a new scheme for exploring potential motif signatures at substrate sites of protein carbonylation. The usefulness of the revealed motifs in the identification of carbonylated sites is demonstrated by their effective performance in cross-validation and independent testing. Finally, these substrate motifs were adopted to build an available online resource (MDD-Carb, http://csb.cse.yzu.edu.tw/MDDCarb/ ) and are also anticipated to facilitate the study of large-scale carbonylated proteomes.

Telephone Flat Geothermal Development Project Environmental Impact Statement Environmental Impact Report. Final

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This Final Environmental Impact Statement and Environmental Impact Report (Final EIS/EIR) has been prepared to meet the requirements of the National Environmental Policy Act (NEPA) and the California Environmental Quality Act (CEQA). The Proposed Action includes the construction, operation, and decommissioning of a 48 megawatt (gross) geothermal power plant with ancillary facilities (10-12 production well pads and 3-5 injection well pads, production and injection pipelines), access roads, and a 230-kilovolt (kV) transmission line in the Modoc National Forest in Siskiyou County, California. Alternative locations for the power plant site within a reasonable distance of the middle of the wellfield weremore » determined to be technically feasible. Three power plant site alternatives are evaluated in the Final EIS/EIR.« less

SUPERFUND TREATABILITY CLEARINGHOUSE: FINAL REPORT, PHASE I - IMMEDIATE ASSESSMENT, ACME SOLVENTS SITE

EPA Science Inventory

This is a site assessment and feasibility study of incineration alternatives at the ACME Solvents Site at Rockford, Illinois. The document contains laboratory results that are reported to simulate incineration conditions but no details on test methods were provided. The d...

The National Visitor Use Monitoring methodology and final results for round 1

Treesearch

S.J. Zarnoch; E.M. White; D.B.K. English; Susan M. Kocis; Ross Arnold

2011-01-01

A nationwide, systematic monitoring process has been developed to provide improved estimates of recreation visitation on National Forest System lands. Methodology is presented to provide estimates of site visits and national forest visits based on an onsite sampling design of site-days and last-exiting recreationists. Stratification of the site days, based on site type...

Integrating multi-criteria decision analysis for a GIS-based hazardous waste landfill sitting in Kurdistan Province, western Iran

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharifi, Mozafar; Hadidi, Mosslem; Vessali, Elahe

2009-10-15

The evaluation of a hazardous waste disposal site is a complicated process because it requires data from diverse social and environmental fields. These data often involve processing of a significant amount of spatial information which can be used by GIS as an important tool for land use suitability analysis. This paper presents a multi-criteria decision analysis alongside with a geospatial analysis for the selection of hazardous waste landfill sites in Kurdistan Province, western Iran. The study employs a two-stage analysis to provide a spatial decision support system for hazardous waste management in a typically under developed region. The purpose ofmore » GIS was to perform an initial screening process to eliminate unsuitable land followed by utilization of a multi-criteria decision analysis (MCDA) to identify the most suitable sites using the information provided by the regional experts with reference to new chosen criteria. Using 21 exclusionary criteria, as input layers, masked maps were prepared. Creating various intermediate or analysis map layers a final overlay map was obtained representing areas for hazardous waste landfill sites. In order to evaluate different landfill sites produced by the overlaying a landfill suitability index system was developed representing cumulative effects of relative importance (weights) and suitability values of 14 non-exclusionary criteria including several criteria resulting from field observation. Using this suitability index 15 different sites were visited and based on the numerical evaluation provided by MCDA most suitable sites were determined.« less

Integrating multi-criteria decision analysis for a GIS-based hazardous waste landfill sitting in Kurdistan Province, western Iran.

PubMed

Sharifi, Mozafar; Hadidi, Mosslem; Vessali, Elahe; Mosstafakhani, Parasto; Taheri, Kamal; Shahoie, Saber; Khodamoradpour, Mehran

2009-10-01

The evaluation of a hazardous waste disposal site is a complicated process because it requires data from diverse social and environmental fields. These data often involve processing of a significant amount of spatial information which can be used by GIS as an important tool for land use suitability analysis. This paper presents a multi-criteria decision analysis alongside with a geospatial analysis for the selection of hazardous waste landfill sites in Kurdistan Province, western Iran. The study employs a two-stage analysis to provide a spatial decision support system for hazardous waste management in a typically under developed region. The purpose of GIS was to perform an initial screening process to eliminate unsuitable land followed by utilization of a multi-criteria decision analysis (MCDA) to identify the most suitable sites using the information provided by the regional experts with reference to new chosen criteria. Using 21 exclusionary criteria, as input layers, masked maps were prepared. Creating various intermediate or analysis map layers a final overlay map was obtained representing areas for hazardous waste landfill sites. In order to evaluate different landfill sites produced by the overlaying a landfill suitability index system was developed representing cumulative effects of relative importance (weights) and suitability values of 14 non-exclusionary criteria including several criteria resulting from field observation. Using this suitability index 15 different sites were visited and based on the numerical evaluation provided by MCDA most suitable sites were determined.

Modelling forest canopy height by integrating airborne LiDAR samples with satellite Radar and multispectral imagery

NASA Astrophysics Data System (ADS)

García, Mariano; Saatchi, Sassan; Ustin, Susan; Balzter, Heiko

2018-04-01

Spatially-explicit information on forest structure is paramount to estimating aboveground carbon stocks for designing sustainable forest management strategies and mitigating greenhouse gas emissions from deforestation and forest degradation. LiDAR measurements provide samples of forest structure that must be integrated with satellite imagery to predict and to map landscape scale variations of forest structure. Here we evaluate the capability of existing satellite synthetic aperture radar (SAR) with multispectral data to estimate forest canopy height over five study sites across two biomes in North America, namely temperate broadleaf and mixed forests and temperate coniferous forests. Pixel size affected the modelling results, with an improvement in model performance as pixel resolution coarsened from 25 m to 100 m. Likewise, the sample size was an important factor in the uncertainty of height prediction using the Support Vector Machine modelling approach. Larger sample size yielded better results but the improvement stabilised when the sample size reached approximately 10% of the study area. We also evaluated the impact of surface moisture (soil and vegetation moisture) on the modelling approach. Whereas the impact of surface moisture had a moderate effect on the proportion of the variance explained by the model (up to 14%), its impact was more evident in the bias of the models with bias reaching values up to 4 m. Averaging the incidence angle corrected radar backscatter coefficient (γ°) reduced the impact of surface moisture on the models and improved their performance at all study sites, with R2 ranging between 0.61 and 0.82, RMSE between 2.02 and 5.64 and bias between 0.02 and -0.06, respectively, at 100 m spatial resolution. An evaluation of the relative importance of the variables in the model performance showed that for the study sites located within the temperate broadleaf and mixed forests biome ALOS-PALSAR HV polarised backscatter was the most important variable, with Landsat Tasselled Cap Transformation components barely contributing to the models for two of the study sites whereas it had a significant contribution at the third one. Over the temperate conifer forests, Landsat Tasselled Cap variables contributed more than the ALOS-PALSAR HV band to predict the landscape height variability. In all cases, incorporation of multispectral data improved the retrieval of forest canopy height and reduced the estimation uncertainty for tall forests. Finally, we concluded that models trained at one study site had higher uncertainty when applied to other sites, but a model developed from multiple sites performed equally to site-specific models to predict forest canopy height. This result suggest that a biome level model developed from several study sites can be used as a reliable estimator of biome-level forest structure from existing satellite imagery.

Public health assessment for McCormick and Baxter Creosoting Company (Portland), Portland, Multnomah County, Oregon, Region 10. Cerclis No. ORD009020603. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-06-13

The McCormick and Baxter Creosoting site is located on the Willamette River in Portland, Oregon. ATSDR considers the site to have been a public health hazard for former plant workers because of past ingestion exposure to arsenic, creosote, pentachlorophenol, polychlorinated dibenzodioxins, and dibenzofurans at levels of public health concern. The site also poses an ongoing and future public health hazard because people might encounter hazardous chemicals along the shoreline on or near the site at levels that can damage the skin, as was reported to have happened to two boys. Finally, dioxin levels would pose a public health hazard ifmore » people subsist on crayfish and suckers contaminated with polychlorinated dibenzodioxins and dibenzofurans.« less

Superfund Record of Decision (EPA Region 2): Love Canal (93rd Street School), Niagara County, City of Niagara Falls, NY. (Third remedial action), (amendment), May 1991. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The Love Canal (93rd Street) site is an inactive hazardous waste site located in Niagara Falls, New York. The 19-acre 93rd Street School site, one of several operable units for the Love Canal Superfund site, is the focus of the Record of Decision (ROD). The fill material is reported to contain fly ash and BHC (a pesticide) waste. The ROD amends the 1988 ROD, and addresses final remediation of onsite contaminated soil through excavation and offsite disposal. The primary contaminants of concern affecting the soil are VOCs including toluene and xylenes; other organics including PAHs and pesticides; and metals includingmore » arsenic, chromium, and lead.« less

Nitrogen-Coordinated Single Cobalt Atom Catalysts for Oxygen Reduction in Proton Exchange Membrane Fuel Cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Xiao Xia; Cullen, David A.; Pan, Yung-Tin

Due to the Fenton reaction, the presence of Fe and peroxide in electrodes generates free radicals causing serious degradation of the organic ionomer and the membrane. Pt-free and Fe-free cathode catalysts therefore are urgently needed for durable and inexpensive proton exchange membrane fuel cells (PEMFCs). In this paper, a high-performance nitrogen-coordinated single Co atom catalyst is derived from Co-doped metal-organic frameworks (MOFs) through a one-step thermal activation. Aberration-corrected electron microscopy combined with X-ray absorption spectroscopy virtually verifies the CoN 4 coordination at an atomic level in the catalysts. Through investigating effects of Co doping contents and thermal activation temperature, anmore » atomically Co site dispersed catalyst with optimal chemical and structural properties has achieved respectable activity and stability for the oxygen reduction reaction (ORR) in challenging acidic media (e.g., half-wave potential of 0.80 V vs reversible hydrogen electrode (RHE). The performance is comparable to Fe-based catalysts and 60 mV lower than Pt/C -60 μg Pt cm -2). Fuel cell tests confirm that catalyst activity and stability can translate to high-performance cathodes in PEMFCs. Finally, the remarkably enhanced ORR performance is attributed to the presence of well-dispersed CoN 4 active sites embedded in 3D porous MOF-derived carbon particles, omitting any inactive Co aggregates.« less

Deep Learning for Automated Extraction of Primary Sites from Cancer Pathology Reports

DOE PAGES

Qiu, John; Yoon, Hong-Jun; Fearn, Paul A.; ...

2017-05-03

Pathology reports are a primary source of information for cancer registries which process high volumes of free-text reports annually. Information extraction and coding is a manual, labor-intensive process. Here in this study we investigated deep learning and a convolutional neural network (CNN), for extracting ICDO- 3 topographic codes from a corpus of breast and lung cancer pathology reports. We performed two experiments, using a CNN and a more conventional term frequency vector approach, to assess the effects of class prevalence and inter-class transfer learning. The experiments were based on a set of 942 pathology reports with human expert annotations asmore » the gold standard. CNN performance was compared against a more conventional term frequency vector space approach. We observed that the deep learning models consistently outperformed the conventional approaches in the class prevalence experiment, resulting in micro and macro-F score increases of up to 0.132 and 0.226 respectively when class labels were well populated. Specifically, the best performing CNN achieved a micro-F score of 0.722 over 12 ICD-O-3 topography codes. Transfer learning provided a consistent but modest performance boost for the deep learning methods but trends were contingent on CNN method and cancer site. Finally, these encouraging results demonstrate the potential of deep learning for automated abstraction of pathology reports.« less

Nitrogen-Coordinated Single Cobalt Atom Catalysts for Oxygen Reduction in Proton Exchange Membrane Fuel Cells

DOE PAGES

Wang, Xiao Xia; Cullen, David A.; Pan, Yung-Tin; ...

2018-01-24

Due to the Fenton reaction, the presence of Fe and peroxide in electrodes generates free radicals causing serious degradation of the organic ionomer and the membrane. Pt-free and Fe-free cathode catalysts therefore are urgently needed for durable and inexpensive proton exchange membrane fuel cells (PEMFCs). In this paper, a high-performance nitrogen-coordinated single Co atom catalyst is derived from Co-doped metal-organic frameworks (MOFs) through a one-step thermal activation. Aberration-corrected electron microscopy combined with X-ray absorption spectroscopy virtually verifies the CoN 4 coordination at an atomic level in the catalysts. Through investigating effects of Co doping contents and thermal activation temperature, anmore » atomically Co site dispersed catalyst with optimal chemical and structural properties has achieved respectable activity and stability for the oxygen reduction reaction (ORR) in challenging acidic media (e.g., half-wave potential of 0.80 V vs reversible hydrogen electrode (RHE). The performance is comparable to Fe-based catalysts and 60 mV lower than Pt/C -60 μg Pt cm -2). Fuel cell tests confirm that catalyst activity and stability can translate to high-performance cathodes in PEMFCs. Finally, the remarkably enhanced ORR performance is attributed to the presence of well-dispersed CoN 4 active sites embedded in 3D porous MOF-derived carbon particles, omitting any inactive Co aggregates.« less

Deep Learning for Automated Extraction of Primary Sites from Cancer Pathology Reports

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qiu, John; Yoon, Hong-Jun; Fearn, Paul A.

Pathology reports are a primary source of information for cancer registries which process high volumes of free-text reports annually. Information extraction and coding is a manual, labor-intensive process. Here in this study we investigated deep learning and a convolutional neural network (CNN), for extracting ICDO- 3 topographic codes from a corpus of breast and lung cancer pathology reports. We performed two experiments, using a CNN and a more conventional term frequency vector approach, to assess the effects of class prevalence and inter-class transfer learning. The experiments were based on a set of 942 pathology reports with human expert annotations asmore » the gold standard. CNN performance was compared against a more conventional term frequency vector space approach. We observed that the deep learning models consistently outperformed the conventional approaches in the class prevalence experiment, resulting in micro and macro-F score increases of up to 0.132 and 0.226 respectively when class labels were well populated. Specifically, the best performing CNN achieved a micro-F score of 0.722 over 12 ICD-O-3 topography codes. Transfer learning provided a consistent but modest performance boost for the deep learning methods but trends were contingent on CNN method and cancer site. Finally, these encouraging results demonstrate the potential of deep learning for automated abstraction of pathology reports.« less

Increased inflammation in sanctuary sites may explain viral blips in HIV infection

DOE PAGES

Piovoso, Michael J.; Cardozo, E. Fabian; Zurakowski, Ryan

2016-08-01

Here, combined antiretroviral therapy (cART) suppress HIV-1 viral replication, such that viral load in plasma remains below the limit of detection in standard assays. However, intermittent episodes of transient viremia (blips) occur in a set of HIV-patients. Given that follicular hyperplasia occurs during lymphoid inflammation as a normal response to infection, it is hypothesised that when the diameter of the lymph node follicle (LNF) increases and crosses a critical size, a viral blip occurs due to cryptic viremia. To study this hypothesis, a theoretical analysis of a mathematical model is performed to find the conditions for virus suppression in allmore » compartments and different scenarios of LNF size changes are simulated. According to the analysis, blips with duration of around 30 days arise when the diameter rise rate is between 0.02 and 0.03 days –1. Moreover, the final diameter of the site is directly related to the steady states of the virus load after the occurrence of a blip. When the value of R 0 is around 2.1, to have a steady-state below the limit of detection after the viral blip, the maximum final diameters should be greater than 0.7 mm so that there is a relative loss of connection between compartments.« less

Increased inflammation in sanctuary sites may explain viral blips in HIV infection.

PubMed

Cardozo, E Fabian; Piovoso, Michael J; Zurakowski, Ryan

2016-08-01

Combined antiretroviral therapy (cART) suppress HIV-1 viral replication, such that viral load in plasma remains below the limit of detection in standard assays. However, intermittent episodes of transient viremia (blips) occur in a set of HIV-patients. Given that follicular hyperplasia occurs during lymphoid inflammation as a normal response to infection, it is hypothesised that when the diameter of the lymph node follicle (LNF) increases and crosses a critical size, a viral blip occurs due to cryptic viremia. To study this hypothesis, a theoretical analysis of a mathematical model is performed to find the conditions for virus suppression in all compartments and different scenarios of LNF size changes are simulated. According to the analysis, blips with duration of around 30 days arise when the diameter rise rate is between 0.02 and 0.03 days(-1). Moreover, the final diameter of the site is directly related to the steady states of the virus load after the occurrence of a blip. When the value of R0 is around 2.1, to have a steady-state below the limit of detection after the viral blip, the maximum final diameters should be greater than 0.7 mm so that there is a relative loss of connection between compartments.

Increased inflammation in sanctuary sites may explain viral blips in HIV infection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piovoso, Michael J.; Cardozo, E. Fabian; Zurakowski, Ryan

Here, combined antiretroviral therapy (cART) suppress HIV-1 viral replication, such that viral load in plasma remains below the limit of detection in standard assays. However, intermittent episodes of transient viremia (blips) occur in a set of HIV-patients. Given that follicular hyperplasia occurs during lymphoid inflammation as a normal response to infection, it is hypothesised that when the diameter of the lymph node follicle (LNF) increases and crosses a critical size, a viral blip occurs due to cryptic viremia. To study this hypothesis, a theoretical analysis of a mathematical model is performed to find the conditions for virus suppression in allmore » compartments and different scenarios of LNF size changes are simulated. According to the analysis, blips with duration of around 30 days arise when the diameter rise rate is between 0.02 and 0.03 days –1. Moreover, the final diameter of the site is directly related to the steady states of the virus load after the occurrence of a blip. When the value of R 0 is around 2.1, to have a steady-state below the limit of detection after the viral blip, the maximum final diameters should be greater than 0.7 mm so that there is a relative loss of connection between compartments.« less

Evaluation of landfill gas production and emissions in a MSW large-scale Experimental Cell in Brazil.

PubMed

Maciel, Felipe Jucá; Jucá, José Fernando Thomé

2011-05-01

Landfill gas (LFG) emissions from municipal solid waste (MSW) landfills are an important environmental concern in Brazil due to the existence of several uncontrolled disposal sites. A program of laboratory and field tests was conducted to investigate gas generation in and emission from an Experimental Cell with a 36,659-ton capacity in Recife/PE - Brazil. This investigation involved waste characterisation, gas production and emission monitoring, and geotechnical and biological evaluations and was performed using three types of final cover layers. The results obtained in this study showed that waste decomposes 4-5 times faster in a tropical wet climate than predicted by traditional first-order models using default parameters. This fact must be included when considering the techniques and economics of projects developed in tropical climate countries. The design of the final cover layer and its geotechnical and biological behaviour proved to have an important role in minimising gas emissions to the atmosphere. Capillary and methanotrophic final cover layers presented lower CH(4) flux rates than the conventional layer. Copyright © 2011 Elsevier Ltd. All rights reserved.

Final Technical Report, City of Brockton Solar Brightfield: Deploying a Solar Array on a Brockton Brownfield

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ribeiro, Lori

The City of Brockton, Massachusetts sought to install New England’s largest solar array at a remediated brownfield site on Grove Street. The 425-kilowatt solar photovoltaic array – or “Brightfield” – was installed in an urban park setting along with interpretive displays to maximize the educational opportunities. The “Brightfield” project included 1,395 310-Watt solar panels connected in “strings” that span the otherwise unusable 3.7-acre site. The project demonstrated that it is both technically and economically feasible to install utility scale solar photovoltaics on a capped landfill site. The US Department of Energy conceived the Brightfields program in 2000, and Brockton’s Brightfieldmore » is the largest such installation nationwide. Brockton’s project demonstrated that while it was both technically and economically feasible to perform such a project, the implementation was extremely challenging due to the state policy barriers, difficulty obtaining grant funding, and level of sophistication required to perform the financing and secure required state approvals. This demonstration project can be used as a model for other communities that wish to implement “Brownfields to Brightfields” projects; 2) implementing utility scale solar creates economies of scale that can help to decrease costs of photovoltaics; 3) the project is an aesthetic, environmental, educational and economic asset for the City of Brockton.« less

Improvement in Oral Health-related Quality of Life by Periodontal Treatment: A Case Report on Elderly Patient with Chronic Periodontitis.

PubMed

Suzuki, Eiichi; Aoki, Hideo; Tomita, Sachiyo; Saito, Atsushi

2016-01-01

We report a case of an elderly patient with chronic periodontitis requiring periodontal surgery. An 86-year-old man presented to Tokyo Dental College Suidobashi Hospital with the chief complaint of tooth fracture in the anterior region and occlusal pain in the posterior region. Clinical examination revealed 47% of sites with a probing depth (PD) of ≥4 mm and 47% of sites with bleeding on probing. Radiographic examination revealed generalized moderate horizontal bone loss with localized vertical defects. A clinical diagnosis of moderate chronic periodontitis was made. The patient's oral health-related quality of life (QoL) was also assessed at the time of each periodontal assessment. Initial periodontal therapy was provided followed by periodontal surgery. Open flap debridement was performed at sites with a PD of ≥5 mm (teeth #15-17). Surgical crown lengthening with an apically positioned flap was performed on #11 and 13 to gain an adequate biological width for the subsequent crown restoration. After confirming the stability of the periodontal tissue, provisional restorations were replaced with final restorations. No further deterioration was observed in the periodontal condition during the subsequent 1-year period of supportive periodontal therapy. Oral health-related QoL was markedly improved by the periodontal therapy. This suggests that periodontal therapy plays an important role in improving and maintaining oral health-related QoL in elderly people.

Artificial redirection of sensation from prosthetic fingers to the phantom hand map on transradial amputees: vibrotactile versus mechanotactile sensory feedback.

PubMed

Antfolk, Christian; D'Alonzo, Marco; Controzzi, Marco; Lundborg, Göran; Rosén, Birgitta; Sebelius, Fredrik; Cipriani, Christian

2013-01-01

This work assesses the ability of transradial amputees to discriminate multi-site tactile stimuli in sensory discrimination tasks. It compares different sensory feedback modalities using an artificial hand prosthesis in: 1) a modality matched paradigm where pressure recorded on the five fingertips of the hand was fed back as pressure stimulation on five target points on the residual limb; and 2) a modality mismatched paradigm where the pressures were transformed into mechanical vibrations and fed back. Eight transradial amputees took part in the study and were divided in two groups based on the integrity of their phantom map; group A had a complete phantom map on the residual limb whereas group B had an incomplete or nonexisting map. The ability in localizing stimuli was compared with that of 10 healthy subjects using the vibration feedback and 11 healthy subjects using the pressure feedback (in a previous study), on their forearms, in similar experiments. Results demonstrate that pressure stimulation surpassed vibrotactile stimulation in multi-site sensory feedback discrimination. Furthermore, we demonstrate that subjects with a detailed phantom map had the best discrimination performance and even surpassed healthy participants for both feedback paradigms whereas group B had the worst performance overall. Finally, we show that placement of feedback devices on a complete phantom map improves multi-site sensory feedback discrimination, independently of the feedback modality.

The Airfloat HL project. [design analysis of airships and lift devices for materials handling

NASA Technical Reports Server (NTRS)

Mowforth, E.

1975-01-01

A design study is described for a large low-cost rigid airship intended primarily for the movement of large indivisible loads (cargo) between industrial sites. A survey of the ship and its overall performance is followed by accounts of the operational procedures for the above function and for an alternative application to unit module transfer between fixed terminals. A final section indicates the estimated costs of construction and operation. Safety factors are also considered. Lifting devices such as winches, hoists are shown and described, and airship configurations are also shown.

Close-Packed Silicon Microelectrodes for Scalable Spatially Oversampled Neural Recording

PubMed Central

Scholvin, Jörg; Kinney, Justin P.; Bernstein, Jacob G.; Moore-Kochlacs, Caroline; Kopell, Nancy; Fonstad, Clifton G.; Boyden, Edward S.

2015-01-01

Objective Neural recording electrodes are important tools for understanding neural codes and brain dynamics. Neural electrodes that are close-packed, such as in tetrodes, enable spatial oversampling of neural activity, which facilitates data analysis. Here we present the design and implementation of close-packed silicon microelectrodes, to enable spatially oversampled recording of neural activity in a scalable fashion. Methods Our probes are fabricated in a hybrid lithography process, resulting in a dense array of recording sites connected to submicron dimension wiring. Results We demonstrate an implementation of a probe comprising 1000 electrode pads, each 9 × 9 μm, at a pitch of 11 μm. We introduce design automation and packaging methods that allow us to readily create a large variety of different designs. Significance Finally, we perform neural recordings with such probes in the live mammalian brain that illustrate the spatial oversampling potential of closely packed electrode sites. PMID:26699649

Providing Diurnal Sky Cover Data at ARM Sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klebe, Dimitri I.

2015-03-06

The Solmirus Corporation was awarded two-year funding to perform a comprehensive data analysis of observations made during Solmirus’ 2009 field campaign (conducted from May 21 to July 27, 2009 at the ARM SGP site) using their All Sky Infrared Visible Analyzer (ASIVA) instrument. The objective was to develop a suite of cloud property data products for the ASIVA instrument that could be implemented in real time and tailored for cloud modelers. This final report describes Solmirus’ research and findings enabled by this grant. The primary objective of this award was to develop a diurnal sky cover (SC) data product utilizingmore » the ASIVA’s infrared (IR) radiometrically-calibrated data and is described in detail. Other data products discussed in this report include the sky cover derived from ASIVA’s visible channel and precipitable water vapor, cloud temperature (both brightness and color), and cloud height inferred from ASIVA’s IR channels.« less

A First Case of Human Trichuriasis from a Roman Lead Coffin in France.

PubMed

Dufour, Benjamin; Segard, Maxence; Le Bailly, Matthieu

2016-10-01

A paleoparasitological study was carried out on 2 lead coffins recovered from the Roman site of Jaunay-Clan (near Poitiers, France). For the first time, this particular type of burial gave positive parasitological results, and eggs of the whipworm Trichuris trichiura were identified in 1 individual. In the present case, thanatomorphose associated with funerary practices may explain the scarcity of the recovered eggs. However, human whipworm has now been observed in 9 individuals dated to the Roman period. The very high frequency of Trichuris sp. eggs in Roman archaeological sites (up to 80%) suggests that fecal peril, hygiene, and waste management were problematic during this period. Finally, due to the fact that very few analyses have been conducted on human bodies dated to the Roman period, more analyses must be performed in the future to provide further information about diseases in the Roman world.

A First Case of Human Trichuriasis from a Roman Lead Coffin in France

PubMed Central

Dufour, Benjamin; Segard, Maxence; Le Bailly, Matthieu

2016-01-01

A paleoparasitological study was carried out on 2 lead coffins recovered from the Roman site of Jaunay-Clan (near Poitiers, France). For the first time, this particular type of burial gave positive parasitological results, and eggs of the whipworm Trichuris trichiura were identified in 1 individual. In the present case, thanatomorphose associated with funerary practices may explain the scarcity of the recovered eggs. However, human whipworm has now been observed in 9 individuals dated to the Roman period. The very high frequency of Trichuris sp. eggs in Roman archaeological sites (up to 80%) suggests that fecal peril, hygiene, and waste management were problematic during this period. Finally, due to the fact that very few analyses have been conducted on human bodies dated to the Roman period, more analyses must be performed in the future to provide further information about diseases in the Roman world. PMID:27853119

Landlord project multi-year program plan, fiscal year 1999, WBS 1.5

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dallas, M.D.

The MYWP technical baseline describes the work to be accomplished by the Project and the technical standards which govern that work. The mission of Landlord Project is to provide more maintenance replacement of general infrastructure facilities and systems to facilitate the Hanford Site cleanup mission. Also, once an infrastructure facility or system is no longer needed the Landlord Project transitions the facility to final closure/removal through excess, salvage or demolition. Landlord Project activities will be performed in an environmentally sound, safe, economical, prudent, and reliable manner. The Landlord Project consists of the following facilities systems: steam, water, liquid sanitary waste,more » electrical distribution, telecommunication, sanitary landfill, emergency services, general purpose offices, general purpose shops, general purpose warehouses, environmental supports facilities, roads, railroad, and the site land. The objectives for general infrastructure support are reflected in two specific areas, (1) Core Infrastructure Maintenance, and (2) Infrastructure Risk Mitigation.« less

Hierarchical effects on target detection and conflict monitoring

PubMed Central

Cao, Bihua; Gao, Feng; Ren, Maofang; Li, Fuhong

2016-01-01

Previous neuroimaging studies have demonstrated a hierarchical functional structure of the frontal cortices of the human brain, but the temporal course and the electrophysiological signature of the hierarchical representation remains unaddressed. In the present study, twenty-one volunteers were asked to perform a nested cue-target task, while their scalp potentials were recorded. The results showed that: (1) in comparison with the lower-level hierarchical targets, the higher-level targets elicited a larger N2 component (220–350 ms) at the frontal sites, and a smaller P3 component (350–500 ms) across the frontal and parietal sites; (2) conflict-related negativity (non-target minus target) was greater for the lower-level hierarchy than the higher-level, reflecting a more intensive process of conflict monitoring at the final step of target detection. These results imply that decision making, context updating, and conflict monitoring differ among different hierarchical levels of abstraction. PMID:27561989

Site-index curves for young-growth ponderosa pine in northern Arizona

Treesearch

Charles O. Minor

1964-01-01

The productive capacity or site quality of an area enters into nearly every phase of forest management from regeneration to final harvest. No standards or measures of site quality have been developed specifically for ponderosa pine in the Southwest, which handicaps the forest manager. The major objective of the present study was to develop the basic site-index curves...

Can patient comorbidities be included in clinical performance measures for radiation oncology?

PubMed

Owen, Jean B; Khalid, Najma; Ho, Alex; Kachnic, Lisa A; Komaki, Ritsuko; Tao, May Lin; Currey, Adam; Wilson, J Frank

2014-05-01

Patient comorbidities may affect the applicability of performance measures that are inherent in multidisciplinary cancer treatment guidelines. This article describes the distribution of common comorbid conditions by disease site and by patient and facility characteristics in patients who received radiation therapy as part of treatment for cancer of the breast, cervix, lung, prostate, and stomach, and investigates the association of comorbidities with treatment decisions. Stratified two-stage cluster sampling provided a random sample of radiation oncology facilities. Eligible patients were randomly sampled from each participating facility for each disease site, and data were abstracted from medical records. The Adult Comorbidity Evaluation Index (ACE-27) was used to measure comorbid conditions and their severity. National estimates were calculated using SUDAAN statistical software. Multivariable logistic regression models predicted the dependent variable "treatment changed or contraindicated due to comorbidities." The final model showed that ACE-27 was highly associated with change in treatment for patients with severe or moderate index values compared to those with none or mild (P < .001). Two other covariates, age and medical coverage, had no (age) or little (medical coverage) significant contribution to predicting treatment change in the multivariable model. Disease site was associated with treatment change after adjusting for other covariates in the model. ACE-27 is highly predictive of treatment modifications for patients treated for these cancers who receive radiation as part of their care. A standardized tool identifying patients who should be excluded from clinical performance measures allows more accurate use of these measures. Copyright © 2014 by American Society of Clinical Oncology.

Can Patient Comorbidities Be Included in Clinical Performance Measures for Radiation Oncology?

PubMed Central

Owen, Jean B.; Khalid, Najma; Ho, Alex; Kachnic, Lisa A.; Komaki, Ritsuko; Tao, May Lin; Currey, Adam; Wilson, J. Frank

2014-01-01

Purpose: Patient comorbidities may affect the applicability of performance measures that are inherent in multidisciplinary cancer treatment guidelines. This article describes the distribution of common comorbid conditions by disease site and by patient and facility characteristics in patients who received radiation therapy as part of treatment for cancer of the breast, cervix, lung, prostate, and stomach, and investigates the association of comorbidities with treatment decisions. Materials and Methods: Stratified two-stage cluster sampling provided a random sample of radiation oncology facilities. Eligible patients were randomly sampled from each participating facility for each disease site, and data were abstracted from medical records. The Adult Comorbidity Evaluation Index (ACE-27) was used to measure comorbid conditions and their severity. National estimates were calculated using SUDAAN statistical software. Results: Multivariable logistic regression models predicted the dependent variable “treatment changed or contraindicated due to comorbidities.” The final model showed that ACE-27 was highly associated with change in treatment for patients with severe or moderate index values compared to those with none or mild (P < .001). Two other covariates, age and medical coverage, had no (age) or little (medical coverage) significant contribution to predicting treatment change in the multivariable model. Disease site was associated with treatment change after adjusting for other covariates in the model. Conclusions: ACE-27 is highly predictive of treatment modifications for patients treated for these cancers who receive radiation as part of their care. A standardized tool identifying patients who should be excluded from clinical performance measures allows more accurate use of these measures. PMID:24643573

76 FR 81840 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-29

... Road Landfill Superfund Site AGENCY: Environmental Protection Agency. ACTION: Direct final rule... Deletion of the Hipps Road Landfill Superfund Site (Site), located in Jacksonville, Florida, from the... than operation, maintenance, and five-year reviews have been completed. However, this deletion does not...

76 FR 41719 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-15

... Road Landfill Superfund Site AGENCY: Environmental Protection Agency. ACTION: Direct final rule... Deletion of the Hipps Road Landfill Superfund Site (Site), located in Jacksonville, Florida, from the... than operation, maintenance, and five-year reviews have been completed. However, this deletion does not...

10 CFR 960.3-2-2-5 - Formal site nomination.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final..., consideration of the available evidence, evaluations, and the resultant findings for the guidelines of subparts...

10 CFR 960.3-2-2-5 - Formal site nomination.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final..., consideration of the available evidence, evaluations, and the resultant findings for the guidelines of subparts...

10 CFR 960.3-2-2-5 - Formal site nomination.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final..., consideration of the available evidence, evaluations, and the resultant findings for the guidelines of subparts...

10 CFR 960.3-2-2-5 - Formal site nomination.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final..., consideration of the available evidence, evaluations, and the resultant findings for the guidelines of subparts...

Steamtown District Heating and Cooling Project, Scranton, Pennsylvania. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This report summarizes the activities of a study intended to examine the feasibility of a district heating and cooling alternative for the Steamtown National Historic Site in Scranton, PA. The objective of the study was to investigate the import of steam from the existing district heating system in Scranton which is operated by the Community Central Energy Corporation and through the use of modern technology provide hot and chilled water to Steamtown for its internal heating and cooling requirements. Such a project would benefit Steamtown by introducing a clean technology, eliminating on-site fuel use, avoiding first costs for central heatingmore » and cooling plants and reducing operation and maintenance expenditures. For operators of the existing district heating system, this project represents an opportunity to expand their customer base and demonstrate new technologies. The study was conducted by Joseph Technology Corporation, Inc. and performed for the Community Central Energy Corporation through a grant by the US Department of Energy. Steamtown was represented by the National Park Service, the developers of the site.« less

FAST TRACK COMMUNICATION: Ground-state fidelity and entanglement entropy for the quantum three-state Potts model in one spatial dimension

NASA Astrophysics Data System (ADS)

Dai, Yan-Wei; Hu, Bing-Quan; Zhao, Jian-Hui; Zhou, Huan-Qiang

2010-09-01

The ground-state fidelity per lattice site is computed for the quantum three-state Potts model in a transverse magnetic field on an infinite-size lattice in one spatial dimension in terms of the infinite matrix product state algorithm. It is found that, on the one hand, a pinch point is identified on the fidelity surface around the critical point, and on the other hand, the ground-state fidelity per lattice site exhibits bifurcations at pseudo critical points for different values of the truncation dimension, which in turn approach the critical point as the truncation dimension becomes large. This implies that the ground-state fidelity per lattice site enables us to capture spontaneous symmetry breaking when the control parameter crosses the critical value. In addition, a finite-entanglement scaling of the von Neumann entropy is performed with respect to the truncation dimension, resulting in a precise determination of the central charge at the critical point. Finally, we compute the transverse magnetization, from which the critical exponent β is extracted from the numerical data.

Strain-mediated electronic properties of pristine and Mn-doped GaN monolayers

NASA Astrophysics Data System (ADS)

Sharma, Venus; Srivastava, Sunita

2018-04-01

Graphene-like two-dimensional (2D) monolayer structures GaN has gained enormous amount of interest due to high thermal stability and inherent energy band gap for practical applications. First principles calculations are performed to investigate the electronic structure and strain-mediated electronic properties of pristine and Mn-doped GaN monolayer. Binding energy of Mn dopant at various adsorption site is found to be nearly same indicating these sites to be equally favorable for adsorption of foreign atom. Depending on the adsorption site, GaN monolayer can act as p-type or n-type magnetic semiconductor. The tensile strength of both pristine and doped GaN monolayer (∼24 GPa) at ultimate tensile strain of 34% is comparable with the tensile strength of graphene. The in-plane biaxial strain modulate the energy band gap of both pristine and doped-monolayer from direct to indirect gap semiconductor and finally retendered theme into metal at critical value of applied strain. These characteristics make GaN monolayer to be potential candidate for the future applications in tunable optoelectronics.

Innovative conception and performance evaluation of a compact on-site treatment system.

PubMed

Sousa, V P; Chernicharo, C A L

2006-01-01

The purpose of this study was to develop a new configuration for a compact on-site treatment system, which could become an attractive alternative, from technical, economic, social and environmental viewpoints, to the technologies that are currently employed. The treatment unit consists of a cylindrical tank, where half of the volume is used as a modified septic tank and the other half is divided between an anaerobic hybrid reactor and a trickling filter. An intermittent feeding system was used, with minimum, mean and maximum flowrate settings (Qmin = 0.25l.s(-1), Qmean = 0.50l.s(-1) and Qmax = 1.00l.s(-1)), to reflect the actual operating conditions of a compact on-site treatment system serving a typical dwelling. An average 24-hour hydraulic detention time was used, corresponding to a flowrate of 750l.d(-1). High removal efficiencies and low concentrations of COD, BOD and TSS in the final effluent were achieved, even when the unit was exposed to hydraulic loading peaks during feeding periods at maximum flowrate.

One Primer To Rule Them All: Universal Primer That Adds BBa_B0034 Ribosomal Binding Site to Any Coding Standard 10 BioBrick

PubMed Central

2015-01-01

Here, we present a universal, simple, efficient, and reliable way to add small BioBrick parts to any BioBrick via PCR that is compatible with BioBrick assembly standard 10. As a proof of principle, we have designed a universal primer, rbs_B0034, that contains a ribosomal binding site (RBS; BBa_B0034) and that can be used in PCR to amplify any coding BioBrick that starts with ATG. We performed test PCRs with rbs_B0034 on 31 different targets and found it to be 93.6% efficient. Moreover, when supplemented with a complementary primer, addition of RBS can be accomplished via whole plasmid site-directed mutagenesis, thus reducing the time required for further assembly of composite parts. The described method brings simplicity to the addition of small parts, such as regulatory elements to existing BioBricks. The final product of the PCR assembly is indistinguishable from the standard or 3A BioBrick assembly. PMID:25524097

Real-Time Pathogen Detection in the Era of Whole-Genome Sequencing and Big Data: Comparison of k-mer and Site-Based Methods for Inferring the Genetic Distances among Tens of Thousands of Salmonella Samples

DOE PAGES

Pettengill, James B.; Pightling, Arthur W.; Baugher, Joseph D.; ...

2016-11-10

The adoption of whole-genome sequencing within the public health realm for molecular characterization of bacterial pathogens has been followed by an increased emphasis on real-time detection of emerging outbreaks (e.g., food-borne Salmonellosis). In turn, large databases of whole-genome sequence data are being populated. These databases currently contain tens of thousands of samples and are expected to grow to hundreds of thousands within a few years. For these databases to be of optimal use one must be able to quickly interrogate them to accurately determine the genetic distances among a set of samples. Being able to do so is challenging duemore » to both biological (evolutionary diverse samples) and computational (petabytes of sequence data) issues. We evaluated seven measures of genetic distance, which were estimated from either k-mer profiles (Jaccard, Euclidean, Manhattan, Mash Jaccard, and Mash distances) or nucleotide sites (NUCmer and an extended multi-locus sequence typing (MLST) scheme). Finally, when analyzing empirical data (wholegenome sequence data from 18,997 Salmonella isolates) there are features (e.g., genomic, assembly, and contamination) that cause distances inferred from k-mer profiles, which treat absent data as informative, to fail to accurately capture the distance between samples when compared to distances inferred from differences in nucleotide sites. Thus, site-based distances, like NUCmer and extended MLST, are superior in performance, but accessing the computing resources necessary to perform them may be challenging when analyzing large databases.« less

Real-Time Pathogen Detection in the Era of Whole-Genome Sequencing and Big Data: Comparison of k-mer and Site-Based Methods for Inferring the Genetic Distances among Tens of Thousands of Salmonella Samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pettengill, James B.; Pightling, Arthur W.; Baugher, Joseph D.

The adoption of whole-genome sequencing within the public health realm for molecular characterization of bacterial pathogens has been followed by an increased emphasis on real-time detection of emerging outbreaks (e.g., food-borne Salmonellosis). In turn, large databases of whole-genome sequence data are being populated. These databases currently contain tens of thousands of samples and are expected to grow to hundreds of thousands within a few years. For these databases to be of optimal use one must be able to quickly interrogate them to accurately determine the genetic distances among a set of samples. Being able to do so is challenging duemore » to both biological (evolutionary diverse samples) and computational (petabytes of sequence data) issues. We evaluated seven measures of genetic distance, which were estimated from either k-mer profiles (Jaccard, Euclidean, Manhattan, Mash Jaccard, and Mash distances) or nucleotide sites (NUCmer and an extended multi-locus sequence typing (MLST) scheme). Finally, when analyzing empirical data (wholegenome sequence data from 18,997 Salmonella isolates) there are features (e.g., genomic, assembly, and contamination) that cause distances inferred from k-mer profiles, which treat absent data as informative, to fail to accurately capture the distance between samples when compared to distances inferred from differences in nucleotide sites. Thus, site-based distances, like NUCmer and extended MLST, are superior in performance, but accessing the computing resources necessary to perform them may be challenging when analyzing large databases.« less

Effluent Management Facility Evaporator Bottom-Waste Streams Formulation and Waste Form Qualification Testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saslow, Sarah A.; Um, Wooyong; Russell, Renee L.

This report describes the results from grout formulation and cementitious waste form qualification testing performed by Pacific Northwest National Laboratory (PNNL) for Washington River Protection Solutions, LLC (WRPS). These results are part of a screening test that investigates three grout formulations proposed for wide-range treatment of different waste stream compositions expected for the Hanford Effluent Management Facility (EMF) evaporator bottom waste. This work supports the technical development need for alternative disposition paths for the EMF evaporator bottom wastes and future direct feed low-activity waste (DFLAW) operations at the Hanford Site. High-priority activities included simulant production, grout formulation, and cementitious wastemore » form qualification testing. The work contained within this report relates to waste form development and testing, and does not directly support the 2017 Integrated Disposal Facility (IDF) performance assessment (PA). However, this work contains valuable information for use in PA maintenance past FY 2017 and future waste form development efforts. The provided results and data should be used by (1) cementitious waste form scientists to further the understanding of cementitious leach behavior of contaminants of concern (COCs), (2) decision makers interested in off-site waste form disposal, and (3) the U.S. Department of Energy, their Hanford Site contractors and stakeholders as they assess the IDF PA program at the Hanford Site. The results reported help fill existing data gaps, support final selection of a cementitious waste form for the EMF evaporator bottom waste, and improve the technical defensibility of long-term waste form risk estimates.« less

Evaluation of Final Radiological Conditions at Areas of the Niagara Falls Storage Site Remediated under the Formerly Utilized Sites Remedial Action Program -12184

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clayton, Christopher; Kothari, Vijendra; Starr, Ken

2012-02-26

The U. S. Department of Energy (DOE) methods and protocols allow evaluation of remediation and final site conditions to determine if remediated sites remain protective. Two case studies are presented that involve the Niagara Falls Storage Site (NFSS) and associated vicinity properties (VPs), which are being remediated under the Formerly Utilized Sites Remedial Action Program (FUSRAP). These properties are a part of the former Lake Ontario Ordnance Works (LOOW). In response to stakeholders concerns about whether certain remediated NFSS VPs were putting them at risk, DOE met with stakeholders and agreed to evaluate protectiveness. Documentation in the DOE records collectionmore » adequately described assessed and final radiological conditions at the completed VPs. All FUSRAP wastes at the completed sites were cleaned up to meet DOE guidelines for unrestricted use. DOE compiled the results of the investigation in a report that was released for public comment. In conducting the review of site conditions, DOE found that stakeholders were also concerned about waste from the Separations Process Research Unit (SPRU) at the Knolls Atomic Power Laboratory (KAPL) that was handled at LOOW. DOE agreed to determine if SPRU waste remained at that needed to be remediated. DOE reviewed records of waste characterization, historical handling locations and methods, and assessment and remediation data. DOE concluded that the SPRU waste was remediated on the LOOW to levels that pose no unacceptable risk and allow unrestricted use and unlimited exposure. This work confirms the following points as tenets of an effective long-term surveillance and maintenance (LTS&M) program: Stakeholder interaction must be open and transparent, and DOE must respond promptly to stakeholder concerns. DOE, as the long-term custodian, must collect and preserve site records in order to demonstrate that remediated sites pose no unacceptable risk. DOE must continue to maintain constructive relationships with the U.S. Army Corps of Engineers and state and federal regulators.« less

Risk Assessment Approach for the Hanford Site River Corridor Closure Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomson, J.E.; Weiss, S.G.; Sands, J.P.

2007-07-01

The river corridor portion of the U.S. Department of Energy's (DOE) Hanford Site includes the 100 Area and 300 Area, which border the Columbia River and cover 565 km{sup 2} (218 mi{sup 2}). The River Corridor Closure (RCC) Project scope of work includes 486 contaminated facilities, 4 of 9 deactivated plutonium production reactors, and 370 waste disposal sites. DOE's cleanup actions in the river corridor were initiated in 1994 under the Comprehensive Environmental Response, Compensation, and Liability Act of 1981 (42 U.S.C. 9601, et seq.) (CERCLA) and included source and groundwater operable units (OUs). DOE's RCC Project, awarded to Washingtonmore » Closure Hanford (WCH) in 2005, focuses on source OUs and has allowed cleanup actions to continue in the 100 and 300 Areas with completion by 2013. The regulatory authorization for cleanup actions at source OUs in the river corridor consists primarily of interim action records of decision (RODs), which were supported by qualitative risk assessments and limited field investigations. A key to establishing final cleanup decisions and proceeding toward final CERCLA closeout is completion of quantitative baseline risk assessment activities. Baseline risk assessment is necessary to determine whether cleanup actions are protective of human health and the environment and to identify any course corrections needed to ensure that current and future cleanup actions are protective. Because cleanup actions are ongoing under interim action RODs, it is desirable to establish the final cleanup decision bases as early as possible to minimize the impacts of any identified course corrections to the cleanup approach. Risk assessment is being performed by WCH as the River Corridor Baseline Risk Assessment (RCBRA). The RCBRA uses a multi-step process that summarizes existing data; uses the data quality objectives process to identify both data gaps and unresolved issues through public workshops; and solicits input from regulators, trustees, and stakeholders. Sampling and analysis plans are then developed to document quality requirements and identify field sample collection approaches. After required data are collected, the risks to human health and the environment are assessed. Sampling of upland, riparian, and near-shore environments for the 100/300 Area Component was performed in 2005 and 2006. The 100/300 Area Component includes former operational/reactor areas. The results of these efforts will be incorporated into a mid-2007 draft risk assessment report for the 100/300 Area Component of the RCBRA. Adapting methodology developed from the 100/300 Area Component, the Inter-Areas risk assessment will be conducted for the riparian and near-shore environments. The Inter-Areas Component includes shoreline areas between former operational areas addressed in the 100/300 Area Component. The Inter-Areas risk assessment will supplement results from the 100/300 Area Component to provide a more complete analysis of residual risks in the river corridor. Plans for the final element of the RCBRA, the Columbia River Component, are being developed by DOE and currently is not part of the RCC Project. The Columbia River Component includes the reach of the Columbia River located adjacent to the Hanford Site and reaches downstream to an undetermined boundary. Recommendations for final cleanup decisions at source units within the river corridor, based in part on the risk assessment results, will be presented for future public review in a River Corridor Source Unit Proposed Plan. To form an integrated cleanup approach for the river corridor, the RCBRA results for the source units require integration with risk assessment results from groundwater cleanup actions managed by other contractors. WCH's risk assessment task includes development of an integration strategy for activities leading up to the final regulatory decisions for all OUs in the river corridor. (authors)« less

Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2, and 118-H-3 Solid Waste Burial Grounds

DOE Office of Scientific and Technical Information (OSTI.GOV)

T. J. Rodovsky

2006-12-06

This report presents the final hazard categorization (FHC) for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2, and 118-H-3 Solid Waste Burial Grounds

DOE Office of Scientific and Technical Information (OSTI.GOV)

T. J. Rodovsky

2007-04-12

This report presents the final hazard categorization (FHC) for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

Commission decision on the Department of Water Resources' Application for Certification for the Bottle Rock Geothermal Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-11-01

The Application for Certification for the construction of a 55 MW geothermal power plant and related facilities in Lake County was approved subject to terms identified in the Final Decision. The following are covered: findings on compliance with statutory site-certification requirements; final environmental impact report; procedural steps; evidentiary bases; need, environmental resources; public health and safety; plant and site safety and reliability; socioeconomic, land use, and cultural concerns, and transmission tap line. (MHR)

Forest type influences transmission of Phytophthora ramorum in California oak woodlands.

PubMed

Davidson, Jennifer M; Patterson, Heather A; Wickland, Allison C; Fichtner, Elizabeth J; Rizzo, David M

2011-04-01

The transmission ecology of Phytophthora ramorum from bay laurel (Umbellularia californica) leaves was compared between mixed-evergreen and redwood forest types throughout winter and summer disease cycles in central, coastal California. In a preliminary multisite study, we found that abscission rates of infected leaves were higher at mixed-evergreen sites. In addition, final infection counts were slightly higher at mixed-evergreen sites or not significantly different than at redwood sites, in part due to competition from other foliar pathogens at redwood sites. In a subsequent, detailed study of paired sites where P. ramorum was the main foliar pathogen, summer survival of P. ramorum in bay laurel leaves was lower in mixed-evergreen forest due to lower recovery from infected attached leaves and higher abscission rates of infected leaves. Onset of inoculum production and new infections of bay laurel leaves occurred later in mixed-evergreen forest. Mean inoculum levels in rainwater and final infection counts on leaves were higher in redwood forest. Based on these two studies, lower summer survival of reservoir inoculum in bay laurel leaves in mixed-evergreen forest may result in delayed onset of both inoculum production and new infections, leading to slower disease progress in the early rainy season compared with redwood forest. Although final infection counts also will depend on other foliar pathogens and disease history, in sites where P. ramorum is the main foliar pathogen, these transmission patterns suggest higher rates of disease spread in redwood forests during rainy seasons of short or average length.

FSA field test

NASA Technical Reports Server (NTRS)

Jaffe, P.; Weaver, R. W.; Lee, R. E.

1981-01-01

The 12 continental remote sites were decommissioned. Testing was consolidated into a five-site network consisting of the four Southern California sites and a new Florida site. 16 kW of new state-of-the-art modules were deployed at the five sites. Testing of the old modules continued at the Goldstone site but as a low-priority item. Array testing of modules is considered. Additional new testing capabilities were added. A battery-powered array data logger is discussed. A final set of failure and degradation data was obtained from the modules.

76 FR 56982 - Announcement of Federal Underground Injection Control (UIC) Class VI Program for Carbon Dioxide (CO2

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-15

... and Administration priorities for developing and deploying CCS projects in the next few years as... VI rule finalized on December 10, 2010. Direct Federal implementation of the final Class VI... on the final Class VI rule, visit the Underground Injection Control Geologic Sequestration Web site...

Predicting the soiling of modern glass in urban environments: A new physically-based model

NASA Astrophysics Data System (ADS)

Alfaro, S. C.; Chabas, A.; Lombardo, T.; Verney-Carron, A.; Ausset, P.

2012-12-01

This study revisits the measurements of the MULTI-ASSESS and Long Term Soiling programs for understanding physically, and modeling, the processes controlling the soiling of modern glass in polluted conditions. The results show a strong correlation between the size distribution of particles and the evolution of the mass deposited at the surface of the glass. Over observation periods covering more than 2 years, the mass deposition on glass panels sheltered from the rain is observed to accelerate regularly with time at the sites closest to the sources of particulate matter (Roadside sites). At these sites the deposit is also richer in coarse (supermicron) mineral particles than at more distant (Urban Background and Suburban) sites, where the contribution of submicron particles (among which a significant fraction of particulate organic matter) is larger. This size and compositional segregation probably explains that the mass accumulation tends to slow down with time and finally saturate after an estimated duration of more than 10 years at the Suburban sites. The analysis of the correlation between the measured accumulated mass and haze shows that the haze-creating mass efficiency of the deposit decreases progressively as the density of particles increases on the glass panels. This is interpreted as being a consequence of the increasing influence of multiple scattering. A steady-state is eventually obtained when layers of closely packed particles are formed, which occurs for surface masses of the order of a few tens of μg cm-2. After this stage is reached, the haze increases linearly with further mass deposition at a pace conditioned by the size-distribution of the deposit. The parameterization of the evolution of the deposited mass with time, and of the correlation linking this mass to the haze allows proposing a new physically-based model able to predict the development of the haze on sheltered glass. Finally, a comparison of the model predictions with the independent measurements performed at the experimental sites of the AERO program shows that the model is able to simulate correctly the development of the haze at a variety of urban sites ranging from the Suburban to Roadside categories. This predictive tool should help developing conservation strategies adapted to the real environmental conditions of the historical and modern buildings.

IRIS Toxicological Review of Methanol (Noncancer) (Final Report)

EPA Science Inventory

EPA conducted a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Methanol (noncancer) , this is finalized and posted on the IRIS Web site.

75 FR 22524 - Ocean Dumping; Designation of Ocean Dredged Material Disposal Sites Offshore of the Siuslaw River...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-29

... location to dispose of material dredged from the Siuslaw River navigation channel, and to provide a... sediments from Site A back into the dredged channel resulted in a selection of disposal Sites B and C by the... conflicts. The final Sites are located close to the approach to the Siuslaw River entrance channel but are...

Layer speciation and electronic structure investigation of freestanding hexagonal boron nitride nanosheets

NASA Astrophysics Data System (ADS)

WangEqual Contribution To This Work., Jian; Wang, Zhiqiang; Cho, Hyunjin; Kim, Myung Jong; Sham, T. K.; Sun, Xuhui

2015-01-01

Chemical imaging, thickness mapping, layer speciation and polarization dependence have been performed on single and multilayered (up to three layers and trilayered nanosheets overlapping to form 6 and 9 layers) hexagonal boron nitride (hBN) nanosheets by scanning transmission X-ray microscopy. Spatially-resolved XANES directly from freestanding regions of different layers has been extracted and compared with sample normal and 30° tilted configurations. Notably a double feature σ* excitonic state and a stable high energy σ* state were observed at the boron site in addition to the intense π* excitonic state. The boron projected σ* DOS, especially the first σ* exciton, is sensitive to surface modification, particularly in the single layered hBN nanosheet which shows more significant detectable contaminants and defects such as tri-coordinated boron/nitrogen oxide. The nitrogen site has shown very weak or no excitonic character. The distinct excitonic effect on boron and nitrogen was interpreted to the partly ionic state of hBN. Bulk XANES of hBN nanosheets was also measured to confirm the spectro-microscopic STXM result. Finally, the unoccupied electronic structures of hBN and graphene were compared.Chemical imaging, thickness mapping, layer speciation and polarization dependence have been performed on single and multilayered (up to three layers and trilayered nanosheets overlapping to form 6 and 9 layers) hexagonal boron nitride (hBN) nanosheets by scanning transmission X-ray microscopy. Spatially-resolved XANES directly from freestanding regions of different layers has been extracted and compared with sample normal and 30° tilted configurations. Notably a double feature σ* excitonic state and a stable high energy σ* state were observed at the boron site in addition to the intense π* excitonic state. The boron projected σ* DOS, especially the first σ* exciton, is sensitive to surface modification, particularly in the single layered hBN nanosheet which shows more significant detectable contaminants and defects such as tri-coordinated boron/nitrogen oxide. The nitrogen site has shown very weak or no excitonic character. The distinct excitonic effect on boron and nitrogen was interpreted to the partly ionic state of hBN. Bulk XANES of hBN nanosheets was also measured to confirm the spectro-microscopic STXM result. Finally, the unoccupied electronic structures of hBN and graphene were compared. Electronic supplementary information (ESI) available. See DOI: 10.1039/c4nr04445b

PDNAsite: Identification of DNA-binding Site from Protein Sequence by Incorporating Spatial and Sequence Context

PubMed Central

Zhou, Jiyun; Xu, Ruifeng; He, Yulan; Lu, Qin; Wang, Hongpeng; Kong, Bing

2016-01-01

Protein-DNA interactions are involved in many fundamental biological processes essential for cellular function. Most of the existing computational approaches employed only the sequence context of the target residue for its prediction. In the present study, for each target residue, we applied both the spatial context and the sequence context to construct the feature space. Subsequently, Latent Semantic Analysis (LSA) was applied to remove the redundancies in the feature space. Finally, a predictor (PDNAsite) was developed through the integration of the support vector machines (SVM) classifier and ensemble learning. Results on the PDNA-62 and the PDNA-224 datasets demonstrate that features extracted from spatial context provide more information than those from sequence context and the combination of them gives more performance gain. An analysis of the number of binding sites in the spatial context of the target site indicates that the interactions between binding sites next to each other are important for protein-DNA recognition and their binding ability. The comparison between our proposed PDNAsite method and the existing methods indicate that PDNAsite outperforms most of the existing methods and is a useful tool for DNA-binding site identification. A web-server of our predictor (http://hlt.hitsz.edu.cn:8080/PDNAsite/) is made available for free public accessible to the biological research community. PMID:27282833

Characterization of the microbial community in a lotic environment to assess the effect of pollution on nitrifying and potentially pathogenic bacteria.

PubMed

Medeiros, J D; Araújo, L X; da Silva, V L; Diniz, C G; Cesar, D E; Del'Duca, A; Coelho, C M

2014-08-01

This study aimed to investigate microbes involved in the nitrogen cycle and potentially pathogenic bacteria from urban and rural sites of the São Pedro stream. Water samples were collected from two sites. A seasonal survey of bacterial abundance was conducted. The dissolved nutrient content was analysed. PCR and FISH analysis were performed to identify and quantify microbes involved in the nitrogen cycle and potentially pathogenic bacteria. The seasonal survey revealed that the bacterial abundance was similar along the year on the rural area but varied on the urban site. Higher concentration of dissolved nutrients in the urban area indicated a eutrophic system. Considering the nitrifying microbes, the genus Nitrobacter was found, especially in the urban area, and may act as the principal bacteria in converting nitrite into nitrate at this site. The molecular markers napA, amoA, and nfrA were more accumulated at the urban site, justifying the higher content of nutrients metabolised by these enzymes. Finally, high intensity of amplicons from Enterococcus, Streptococcus, Bacteroides/Prevotella/Porphyromonas, Salmonella, S. aureus, P. aeruginosa and the diarrheagenic lineages of E. coli were observed at the urban site. These results indicate a change in the structure of the microbial community imposed by anthrophic actions. The incidence of pathogenic bacteria in aquatic environments is of particular importance to public health, emphasising the need for sewage treatment to minimise the environmental impacts associated with urbanisation.

Science plus management equals successful remediation -- A case study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buehlman, M.D.; Rogers, D.T.; Payne, F.C.

In the past, owners of contaminated sites attempted to remediate as quickly as possible, usually by excavating contaminated soil or pumping and treating contaminated groundwater. Often, they started remediation before identifying all potential types and sources of contaminants, and before conducting a thorough hydrogeologic study. Such premature action usually resulted in the selected remedy not working, the contamination spreading, or unnecessary remedial activities. Today, successful site remediation is recognized as a complex and time-consuming undertaking--requiring a combination of careful scientific study, effective negotiation with the regulatory agencies and skillful management of multidisciplinary efforts. A case study involving a Brownfields sitemore » in southeastern Michigan clearly illustrates the elements of successful remediation. The site`s soil was contaminated with polychlorinated biphenyls (PCBs) and its groundwater with a variety of chlorinated solvents. The original estimate for remediation had exceeded $30 million. Several phases of investigation were conducted to evaluate the nature and sources of contaminants, the site`s hydrogeology, potential risks to human health and the environment, and feasible remedial technologies. Multiple cleanup criteria were established for different affected areas based on the results of the investigations, changes that were taking place with the state cleanup regulations and standards and subsequent negotiations with state and federal regulators. Innovative remedial technologies were selected. The result was a remediation that met or exceeded all soil and groundwater cleanup objectives, was performed on schedule, and was highly cost-effective. The final cost was limited to $3 million--one-tenth of the original estimate.« less

77 FR 57495 - National Priorities List, Final Rule No. 55

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-18

... EPA is responsible for preparing a Hazard Ranking System (``HRS'') score and determining whether the... an NPL construction completion list (``CCL'') to simplify its system of categorizing sites and to...). Inclusion of a site on the CCL has no legal significance. Sites qualify for the CCL when: (1) Any necessary...

Economics of site preparation and release treatments using herbicides in Central Georgia

Treesearch

Rodney L. Busby; James H. Miller; M. Boyd Edwards

1998-01-01

Abstract. Land expectation values (LEV) of site preparation and release treatments using herbicides in central Georgia are calculated and compared Loblolly pine growth and hardwood competition levels were measured at age 6 for the site preparation treatments and age 8 for the release treatments. These measurements were projected to final harvest...

Analysis, results and conclusion of magnetotelluric data acquired in northern Switzerland

NASA Astrophysics Data System (ADS)

Shah, Neeraj; Samrock, Friedemann; Grayver, Alexander; Saar, Martin O.

2017-04-01

In early 2016, a magnetotelluric (MT) survey of the Aargau region of northern Switzerland was performed in order to understand the potential of the magnetotelluric method to characterise the electrical resistivity properties of the subsurface in Switzerland, and more widely, in areas with high amounts of cultural electromagnetic (EM) noise. Subsurface electrical resisitivity properties are interesting as they can help identify underground aquifers or geothermal resources and possibly provide insight into the large-scale movement of fluid. The north of Switzerland is a challenging and representative environment, with significant EM infrastructure, including powerlines and numerous other sources of noise related to human activity and use of industrial equipment. Here, we present the results of the survey together with detailed analysis of the issues encountered and challenges faced when doing this survey. In particular, we concentrate on data quality issues in the raw time series, the impact of using a remote reference over single site processing and the distribution of transfer functions. The final set of transfer functions for the survey, which includes twelve successful sites, is shown to suffer from noise issues in certain frequency ranges. A 1-D inversion of SSQ averaged transfer functions and comparison to existing borehole data demonstrates that geologic data is captured in the MT data recorded in northern Switzerland. Further, 2-D forward modelling supports the idea that good geologic information exists in the data despite the noise issues, which for now, impede a robust multi-dimensional inversion. Finally, suggestions for future work and methods to improve the quality of data when surveying in high EM noise environments are offered with a view to being able to reliably perform MT surveys closer to urban environments.

Health-related quality-of-life parameters as independent prognostic factors in advanced or metastatic bladder cancer.

PubMed

Roychowdhury, D F; Hayden, A; Liepa, A M

2003-02-15

This retrospective analysis examined prognostic significance of health-related quality-of-life (HRQoL) parameters combined with baseline clinical factors on outcomes (overall survival, time to progressive disease, and time to treatment failure) in bladder cancer. Outcome and HRQoL (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30) data were collected prospectively in a phase III study assessing gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in locally advanced or metastatic bladder cancer. Prespecified baseline clinical factors (performance status, tumor-node-metastasis staging, visceral metastases [VM], alkaline phosphatase [AP] level, number of metastatic sites, prior radiotherapy, disease measurability, sex, time from diagnosis, and sites of disease) and selected HRQoL parameters (global QoL; all functional scales; symptoms: pain, fatigue, insomnia, dyspnea, anorexia) were evaluated using Cox's proportional hazards model. Factors with individual prognostic value (P <.05) on outcomes in univariate models were assessed for joint prognostic value in a multivariate model. A final model was developed using a backward selection strategy. Patients with baseline HRQoL were included (364 of 405, 90%). The final model predicted longer survival with low/normal AP levels, no VM, high physical functioning, low role functioning, and no anorexia. Positive prognostic factors for time to progressive disease were good performance status, low/normal AP levels, no VM, and minimal fatigue; for time to treatment failure, they were low/normal AP levels, minimal fatigue, and no anorexia. Global QoL was a significant predictor of outcome in univariate analyses but was not retained in the multivariate model. HRQoL parameters are independent prognostic factors for outcome in advanced bladder cancer; their prognostic importance needs further evaluation.

Evaluation of performance, safety, subject acceptance, and compliance of a disposable autoinjector for subcutaneous injections in healthy volunteers.

PubMed

Berteau, Cecile; Schwarzenbach, Florence; Donazzolo, Yves; Latreille, Mathilde; Berube, Julie; Abry, Herve; Cotten, Joël; Feger, Celine; Laurent, Philippe E

2010-10-05

A disposable autoinjector was developed for subcutaneous (SC) self-injection by patients with chronic diseases. To verify its performance and evaluate its acceptance, a clinical study was conducted in healthy volunteers, comparing SC injections performed by subjects using the autoinjector with SC injections performed by nurses using a syringe. This was a randomized, single-center, crossover study comparing SC self-injection using an autoinjector with SC nurse-administered injection using a syringe. Two volumes (0.2 mL and 1 mL) were injected into healthy volunteers. Study objectives included assessment of the accuracy and consistency of the volume injected by the injection systems, and skin reaction and pain associated with the injection. The fluid depot in the SC tissue layer was evaluated by ultrasound. Subject acceptance was evaluated using questionnaires on attitudes and emotions towards the injection technique, and challenged by seeking the subjects' preferred system for a final study injection or future treatment. A total of 960 injections (480 with autoinjector, 480 with syringe) were performed in 40 subjects. There were no significant differences in mean fluid leakage and injected volumes between the systems. Pain associated with the injection was significantly lower with the auto-injector than with the syringe. Local skin reaction at the injection site was overall satisfactory. Injections were appropriately performed by all subjects. At study end, all 40 subjects preferred the autoinjector for a final study injection and for future treatment. This study indicated that the autoinjector used by the subject was similar to a syringe used by a nurse in terms of performance and safety in administering the injections, and better in terms of pain, overall acceptance, and preference.

75 FR 4803 - Notice of Availability of the Final Environmental Impact Statement for Decommissioning and/or...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-29

...). The Proposed Action includes the decontamination and decommissioning of the waste storage tanks and... site facilities identified in the Final EIS would be removed; contaminated soil, sediment, and...

Structural evolution of molybdenum carbides in hot aqueous environments and impact on low-temperature hydroprocessing of acetic acid

DOE PAGES

Choi, Jae -Soon; Schwartz, Viviane; Santillan-Jimenez, Eduardo; ...

2015-03-13

In this paper, we investigated the structural evolution of molybdenum carbides subjected to hot aqueous environments and their catalytic performance in low-temperature hydroprocessing of acetic acid. While bulk structures of Mo carbides were maintained after aging in hot liquid water, a portion of carbidic Mo sites were converted to oxidic sites. Water aging also induced changes to the non-carbidic carbon deposited during carbide synthesis and increased surface roughness, which in turn affected carbide pore volume and surface area. The extent of these structural changes was sensitive to the initial carbide structure and was lower under actual hydroprocessing conditions indicating themore » possibility of further improving the hydrothermal stability of Mo carbides by optimizing catalyst structure and operating conditions. Mo carbides were active in acetic acid conversion in the presence of liquid water, their activity being comparable to that of Ru/C. Finally, the results suggest that effective and inexpensive bio-oil hydroprocessing catalysts could be designed based on Mo carbides, although a more detailed understanding of the structure-performance relationships is needed, especially in upgrading of more complex reaction mixtures or real bio-oils.« less

BFS Simulation and Experimental Analysis of the Effect of Ti Additions on the Structure of NiAl

NASA Technical Reports Server (NTRS)

Bozzolo, Guillermo; Noebe, Ronald D.; Ferrante,John; Garg, Anita; Honecy, Frank S.; Amador, Carlos

1999-01-01

The Bozzolo-Ferrante-Smith (BFS) method for alloy energetics is applied to the study of ternary additions to NiAl. A description of the method and its application to alloy design is given. Two different approaches are used in the analysis of the effect of Ti additions to NiAl. First, a thorough analytical study is performed, where the energy of formation, lattice parameter and bulk modulus are calculated for a large number of possible atomic distributions of Ni, Al and Ti. Substitutional site preference schemes and formation of precipitates are thus predicted and analyzed. The second approach used consists of the determination of temperature effects on the final results, as obtained by performing a number of large scale numerical simulations using the Monte Carlo-Metropolis procedure and BFS for the calculation of the energy at every step in the simulation. The results indicate a sharp preference of Ti for Al sites in Ni-rich NiAl alloys and the formation of ternary Heusler precipitates beyond the predicted solubility limit of 5 at. % Ti. Experimental analysis of three Ni-Al-Ti alloys confirms the theoretical predictions.

Synthesis and characterization of n-type NiO:Al thin films for fabrication of p-n NiO homojunctions

NASA Astrophysics Data System (ADS)

Sun, Hui; Liao, Ming-Han; Chen, Sheng-Chi; Li, Zhi-Yue; Lin, Po-Chun; Song, Shu-Mei

2018-03-01

n-type NiO:Al thin films were deposited by RF magnetron sputtering. Their optoelectronic properties versus Al target power was investigated. The results show that with increasing Al target power, the conduction type of NiO films changes from p-type to n-type. The variation of the film’s electrical and optical properties depends on Al amount in the film. When Al target power is relatively low, Al3+ cations tend to enter nickel vacancy sites, which makes the lattice structure of NiO more complete. This improves the carrier mobility and film’s transmittance. However, when Al target power exceeds 40 W, Al atoms begin to enter into interstitial sites and form an Al cluster in the NiO film. This behavior is beneficial for improving the film’s n-type conductivity but degrades the film’s transmittance. Finally, Al/(p-type NiO)/(n-type NiO:Al)/ITO homojunctions were fabricated. Their performance was compared with Al/(p-type NiO)/ITO heterojunctions without an n-type NiO layer. Thanks to the better interface quality between the two NiO layers, the homojunctions present better performance.

Atomistic Simulations and Experimental Analysis of the Effect of Ti Additions on the Structure of NiAl

NASA Technical Reports Server (NTRS)

Bozzolo, Guillermo; Noebe, Ronald D.; Ferrante, John; Garg, Anita; Amador, Carlos

1997-01-01

The Bozzolo-Ferrante-Smith (BFS) semiempirical method for alloy energetics is applied to the study of ternary additions to NiAl alloys. A detailed description of the method and its application to alloy design is given. Two different approaches are used in the analysis of the effect of Ti additions to NiAl. First, a thorough analytical study is performed, where the energy of formation, lattice parameter and bulk modulus are calculated for hundreds of possible atomic distributions of Ni, Al and Ti. Substitutional site preference schemes and formation of precipitates are thus predicted and analyzed. The second approach used consists of the determination of temperature effects on the final results, as obtained by performing a number of large scale numerical simulations using the Monte Carlo - Metropolis procedure and BFS for the calculation of the energy at every step in the simulation. The results indicate a sharp preference of Ti for Al sites in Ni-rich NiAl alloys and the formation of ternary Heusler precipitates beyond the predicted solubility limit of 5 at. % Ti. Experimental analysis of three NiAl+Ti alloys confirms the theoretical predictions.

78 FR 15358 - DOE's Preferred Alternative for Certain Tanks Evaluated in the Final Tank Closure and Waste...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-11

... SUPPLEMENTARY INFORMATION.) \\1\\ Transuranic (TRU) waste is waste that contains alpha particle-emitting... available on the DOE NEPA Web site at http://energy.gov/nepa . Additional information on the Final TC & WM... INFORMATION CONTACT: For further information on the Final TC & WM EIS, contact Ms. Burandt as listed in...

Insights into factorless translational initiation by the tRNA-like pseudoknot domain of a viral IRES.

PubMed

Au, Hilda H T; Jan, Eric

2012-01-01

The intergenic region internal ribosome entry site (IGR IRES) of the Dicistroviridae family adopts an overlapping triple pseudoknot structure to directly recruit the 80S ribosome in the absence of initiation factors. The pseudoknot I (PKI) domain of the IRES mimics a tRNA-like codon:anticodon interaction in the ribosomal P site to direct translation initiation from a non-AUG initiation codon in the A site. In this study, we have performed a comprehensive mutational analysis of this region to delineate the molecular parameters that drive IRES translation. We demonstrate that IRES-mediated translation can initiate at an alternate adjacent and overlapping start site, provided that basepairing interactions within PKI remain intact. Consistent with this, IGR IRES translation tolerates increases in the variable loop region that connects the anticodon- and codon-like elements within the PKI domain, as IRES activity remains relatively robust up to a 4-nucleotide insertion in this region. Finally, elements from an authentic tRNA anticodon stem-loop can functionally supplant corresponding regions within PKI. These results verify the importance of the codon:anticodon interaction of the PKI domain and further define the specific elements within the tRNA-like domain that contribute to optimal initiator Met-tRNA(i)-independent IRES translation.

Insights into Factorless Translational Initiation by the tRNA-Like Pseudoknot Domain of a Viral IRES

PubMed Central

Au, Hilda H. T.; Jan, Eric

2012-01-01

The intergenic region internal ribosome entry site (IGR IRES) of the Dicistroviridae family adopts an overlapping triple pseudoknot structure to directly recruit the 80S ribosome in the absence of initiation factors. The pseudoknot I (PKI) domain of the IRES mimics a tRNA-like codon:anticodon interaction in the ribosomal P site to direct translation initiation from a non-AUG initiation codon in the A site. In this study, we have performed a comprehensive mutational analysis of this region to delineate the molecular parameters that drive IRES translation. We demonstrate that IRES-mediated translation can initiate at an alternate adjacent and overlapping start site, provided that basepairing interactions within PKI remain intact. Consistent with this, IGR IRES translation tolerates increases in the variable loop region that connects the anticodon- and codon-like elements within the PKI domain, as IRES activity remains relatively robust up to a 4-nucleotide insertion in this region. Finally, elements from an authentic tRNA anticodon stem-loop can functionally supplant corresponding regions within PKI. These results verify the importance of the codon:anticodon interaction of the PKI domain and further define the specific elements within the tRNA-like domain that contribute to optimal initiator Met-tRNAi-independent IRES translation. PMID:23236506

Prediction of human disease-associated phosphorylation sites with combined feature selection approach and support vector machine.

PubMed

Xu, Xiaoyi; Li, Ao; Wang, Minghui

2015-08-01

Phosphorylation is a crucial post-translational modification, which regulates almost all cellular processes in life. It has long been recognised that protein phosphorylation has close relationship with diseases, and therefore many researches are undertaken to predict phosphorylation sites for disease treatment and drug design. However, despite the success achieved by these approaches, no method focuses on disease-associated phosphorylation sites prediction. Herein, for the first time the authors propose a novel approach that is specially designed to identify associations between phosphorylation sites and human diseases. To take full advantage of local sequence information, a combined feature selection method-based support vector machine (CFS-SVM) that incorporates minimum-redundancy-maximum-relevance filtering process and forward feature selection process is developed. Performance evaluation shows that CFS-SVM is significantly better than the widely used classifiers including Bayesian decision theory, k nearest neighbour and random forest. With the extremely high specificity of 99%, CFS-SVM can still achieve a high sensitivity. Besides, tests on extra data confirm the effectiveness and general applicability of CFS-SVM approach on a variety of diseases. Finally, the analysis of selected features and corresponding kinases also help the understanding of the potential mechanism of disease-phosphorylation relationships and guide further experimental validations.

Mixed waste landfill corrective measures study final report Sandia National Laboratories, Albuquerque, New Mexico.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peace, Gerald; Goering, Timothy James

2004-03-01

The Mixed Waste Landfill occupies 2.6 acres in the north-central portion of Technical Area 3 at Sandia National Laboratories, Albuquerque, New Mexico. The landfill accepted low-level radioactive and mixed waste from March 1959 to December 1988. This report represents the Corrective Measures Study that has been conducted for the Mixed Waste Landfill. The purpose of the study was to identify, develop, and evaluate corrective measures alternatives and recommend the corrective measure(s) to be taken at the site. Based upon detailed evaluation and risk assessment using guidance provided by the U.S. Environmental Protection Agency and the New Mexico Environment Department, themore » U.S. Department of Energy and Sandia National Laboratories recommend that a vegetative soil cover be deployed as the preferred corrective measure for the Mixed Waste Landfill. The cover would be of sufficient thickness to store precipitation, minimize infiltration and deep percolation, support a healthy vegetative community, and perform with minimal maintenance by emulating the natural analogue ecosystem. There would be no intrusive remedial activities at the site and therefore no potential for exposure to the waste. This alternative poses minimal risk to site workers implementing institutional controls associated with long-term environmental monitoring as well as routine maintenance and surveillance of the site.« less

10 CFR 603.890 - Final performance report.

Code of Federal Regulations, 2010 CFR

2010-01-01

... to Other Administrative Matters Financial and Programmatic Reporting § 603.890 Final performance report. A TIA must require a final performance report that addresses all major accomplishments under the... 10 Energy 4 2010-01-01 2010-01-01 false Final performance report. 603.890 Section 603.890 Energy...

Free range users and one hit wonders: community users of an Internet-based cognitive behaviour therapy program.

PubMed

Christensen, Helen; Griffiths, Kathy; Groves, Chloe; Korten, Ailsa

2006-01-01

Little is known about the predictors of symptom change or the methods that might increase user 'compliance' on websites designed to improve mental health outcomes. The present paper: (i) examines predictors of expected final depression and anxiety scores on the MoodGYM website as a function of user characteristics; and (ii) compares the compliance rates of the original site with the new public version of the site (MoodGYM Mark II). The latter site requires compulsory completion of 'core' online assessments and may increase completion of site questionnaires. MoodGYM Mark I participants were 19,607 visitors (public registrants) between April 2001 and September 2003 plus 182 participants who had been randomly assigned to MoodGYM in an earlier trial (The BlueMood Trial). MoodGYM Mark II participants were 38,791 public registrants of the MoodGYM Mark II site collected between September 2003 and October 2004. Symptom assessments are repeated within the website intervention to allow the examination of change in symptoms. Outcome variables were gender, initial depression severity scores, number of assessments completed and final anxiety and depression scores. Men are predicted to be 0.19 units (SE=0.095) higher than women on depression, controlling for the initial depression level and number of modules completed. For initial depression scores above 2, it is predicted that the final score will indicate improvement relative to the initial score, the magnitude of the improvement increasing as a function of the number of modules attempted. For initial anxiety scores above 2, it is predicted that the final score will indicate improvement relative to the initial score, the magnitude of the improvement increasing as a function of the number of modules attempted. Mark II registrants were more likely than to Mark I registrants to complete onsite assessments. Visitors to the MoodGYM site are likely to have better psychological outcomes if they complete more of the site material. Compulsory completion of core sections increases assessment completion. There is a need to examine further the significance of attrition from online interventions, to develop methods of handling missing data, and to investigate strategies to improve visitor dropout.

Site 300 Bat Monitoring Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Drennan, Joe; Tortosa, Justin

2016-07-18

From June 15 to 18, 2015, GANDA biologist Graham Neale assisted in programming and fieldtesting of the bat monitoring equipment. The equipment was deployed in the field on a meteorological (MET) tower within Site 300 on June 18, 2015.

Urinary 1-hydroxypyrene concentration as an exposure biomarker to polycyclic aromatic hydrocarbons (PAHs) in Mexican women from different hot spot scenarios and health risk assessment.

PubMed

Pruneda-Álvarez, Lucia G; Pérez-Vázquez, Francisco J; Ruíz-Vera, Tania; Ochoa-Martínez, Ángeles C; Orta-García, Sandra T; Jiménez-Avalos, Jorge A; Pérez-Maldonado, Iván N

2016-04-01

Recently, in developing countries, polycyclic aromatic hydrocarbons (PAHs) have been considered contaminants of grave concern for women and children. Therefore, the aim of this study was twofold: (1) evaluate exposure assessment to PAHs using urinary 1-hydroxypyrene (1-OHP) as an exposure biomarker and (2) perform a health risk assessment in women from four different high risk scenarios in Mexico. From 2012 to 2013, in a cross-sectional study, we evaluated a total of 184 healthy women from the following scenarios: (A) indoor biomass combustion site (n = 50); (B) brick manufacturing site using different materials such as fuel sources (n = 70); (C) industrial site (n = 44); and (D) high vehicular traffic site (n = 20). 1-hydroxypyrene (1-OHP) was quantified using a high-performance liquid chromatography (HPLC) technique. Afterward, a probabilistic health risk assessment was performed (Monte Carlo analysis). Mean urinary 1-OHP levels found were 0.92 ± 0.92; 0.91 ± 0.83; 0.22 ± 0.19; and 0.14 ± 0.17 μg/L for scenario A, B, C, and D, respectively. Then, based on the measured urinary 1-OHP levels, the estimated median daily intake doses of pyrene were calculated: 659, 623, 162, and 77.4 ng/kg/day for the women participating in the study living in areas A, B, C, and D, respectively, and finally, the hazard quotient (HQ) was calculated (22 ± 21, 21 ± 20, 5.5 ± 5.5, and 2.6 ± 3.5; for areas A, B, C, and D, respectively), high health risk was noted for the women living in the studied communities. The data shown in this study (exposure levels to PAHs and health risk assessment) made it reasonable to conclude that the exposure levels found have a significant potential for generating adverse effects on human health in the studied scenarios.

Photosynthesis and the web: 2001.

PubMed

Orr, L

2001-01-01

First, a brief history of the Internet and the World Wide Web is presented. This is followed by relevant information on photosynthesis-related web sites grouped into several categories: (1) large group sites, (2) comprehensive overview sites, (3) specific subject sites, (4) individual researcher sites, (5) kindergarten through high school (K-12) educational sites, (6) books and journals, and, 7) other useful sites. A section on searching the Web is also included. Finally, we have included an appendix with all of the web sites discussed herein as well as other web sites that space did not allow. Readers are requested to send comments, corrections and additions to gov@uiuc.edu.

Cord blood DNA methylation and adiposity measures in early and mid-childhood.

PubMed

Kresovich, Jacob K; Zheng, Yinan; Cardenas, Andres; Joyce, Brian T; Rifas-Shiman, Sheryl L; Oken, Emily; Gillman, Matthew W; Hivert, Marie-France; Baccarelli, Andrea A; Hou, Lifang

2017-01-01

Excess adiposity in childhood is associated with numerous adverse health outcomes. As this condition is difficult to treat once present, identification of risk early in life can help inform and implement strategies to prevent the onset of the condition. We performed an epigenome-wide association study to prospectively investigate the relationship between cord blood DNA methylation and adiposity measurements in childhood. We measured genome-wide DNA methylation from 478 children in cord blood and measured overall and central adiposity via skinfold caliper measurements in early (range 3.1-3.3 years) and mid-childhood (age range 7.3-8.3 years) and via dual X-ray absorptiometry (DXA) in mid-childhood. Final models were adjusted for maternal age at enrollment, pre-pregnancy body mass index, education, folate intake during pregnancy, smoking during pregnancy, and gestational weight gain, and child sex, race/ethnicity, current age, and cord blood cell composition. We identified four promoter proximal CpG sites that were associated with adiposity as measured by subscapular (SS) and triceps (TR) ratio (SS:TR) in early childhood, in the genes KPRP , SCL9A10 , MYLK2 , and PRLHR . We additionally identified one gene body CpG site associated with early childhood SS + TR on PPAPDC1A ; this site was nominally associated with SS + TR in mid-childhood. Higher methylation at one promoter proximal CpG site in MMP25 was also associated with SS:TR in mid-childhood. In regional analyses, methylation at an exonal region of GFPT2 was positively associated with SS:TR in early childhood. Finally, we identified regions of two long, non-coding RNAs which were associated with SS:TR (LOC100049716) and fat-free mass index (LOC102723493) in mid-childhood. This analysis identified novel CpG loci associated with adiposity outcomes. However, our results suggest little consistency across the various adiposity outcomes tested, particularly among the more accurate DXA measurements of body composition. We recommend using caution when interpreting these associations.

The crystal structure of dihydrodipicolinate synthase from Escherichia coli with bound pyruvate and succinic acid semialdehyde: unambiguous resolution of the stereochemistry of the condensation product.

PubMed

Boughton, Berin A; Dobson, Renwick C J; Hutton, Craig A

2012-08-01

The crystal structure of Escherichia coli dihydrodipicolinate synthase with pyruvate and substrate analogue succinic acid semialdehyde condensed with the active site lysine-161 was solved to a resolution of 2.3 Å. Comparative analysis to a previously reported structure both resolves the configuration at the aldol addition center, where the final addition product clearly displays the (S)-configuration, and the final conformation of the adduct within the active site. Direct comparison to two other crystal structures found in the Protein Data Bank, 1YXC, and 3DU0, demonstrates significant similarity between the active site residues of these structures. Copyright © 2012 Wiley Periodicals, Inc.

Peak ground motion predictions with empirical site factors using Taiwan Strong Motion Network recordings

NASA Astrophysics Data System (ADS)

Chung, Jen-Kuang

2013-09-01

A stochastic method called the random vibration theory (Boore, 1983) has been used to estimate the peak ground motions caused by shallow moderate-to-large earthquakes in the Taiwan area. Adopting Brune's ω-square source spectrum, attenuation models for PGA and PGV were derived from path-dependent parameters which were empirically modeled from about one thousand accelerograms recorded at reference sites mostly located in a mountain area and which have been recognized as rock sites without soil amplification. Consequently, the predicted horizontal peak ground motions at the reference sites, are generally comparable to these observed. A total number of 11,915 accelerograms recorded from 735 free-field stations of the Taiwan Strong Motion Network (TSMN) were used to estimate the site factors by taking the motions from the predictive models as references. Results from soil sites reveal site amplification factors of approximately 2.0 ~ 3.5 for PGA and about 1.3 ~ 2.6 for PGV. Finally, as a result of amplitude corrections with those empirical site factors, about 75% of analyzed earthquakes are well constrained in ground motion predictions, having average misfits ranging from 0.30 to 0.50. In addition, two simple indices, R 0.57 and R 0.38, are proposed in this study to evaluate the validity of intensity map prediction for public information reports. The average percentages of qualified stations for peak acceleration residuals less than R 0.57 and R 0.38 can reach 75% and 54%, respectively, for most earthquakes. Such a performance would be good enough to produce a faithful intensity map for a moderate scenario event in the Taiwan region.

Active Site Hydrophobicity and the Convergent Evolution of Paraoxonase Activity in Structurally Divergent Enzymes: The Case of Serum Paraoxonase 1

PubMed Central

2016-01-01

Serum paraoxonase 1 (PON1) is a native lactonase capable of promiscuously hydrolyzing a broad range of substrates, including organophosphates, esters, and carbonates. Structurally, PON1 is a six-bladed β-propeller with a flexible loop (residues 70–81) covering the active site. This loop contains a functionally critical Tyr at position 71. We have performed detailed experimental and computational analyses of the role of selected Y71 variants in the active site stability and catalytic activity in order to probe the role of Y71 in PON1’s lactonase and organophosphatase activities. We demonstrate that the impact of Y71 substitutions on PON1’s lactonase activity is minimal, whereas the kcat for the paraoxonase activity is negatively perturbed by up to 100-fold, suggesting greater mutational robustness of the native activity. Additionally, while these substitutions modulate PON1’s active site shape, volume, and loop flexibility, their largest effect is in altering the solvent accessibility of the active site by expanding the active site volume, allowing additional water molecules to enter. This effect is markedly more pronounced in the organophosphatase activity than the lactonase activity. Finally, a detailed comparison of PON1 to other organophosphatases demonstrates that either a similar “gating loop” or a highly buried solvent-excluding active site is a common feature of these enzymes. We therefore posit that modulating the active site hydrophobicity is a key element in facilitating the evolution of organophosphatase activity. This provides a concrete feature that can be utilized in the rational design of next-generation organophosphate hydrolases that are capable of selecting a specific reaction from a pool of viable substrates. PMID:28026940

Active Site Hydrophobicity and the Convergent Evolution of Paraoxonase Activity in Structurally Divergent Enzymes: The Case of Serum Paraoxonase 1.

PubMed

Blaha-Nelson, David; Krüger, Dennis M; Szeler, Klaudia; Ben-David, Moshe; Kamerlin, Shina Caroline Lynn

2017-01-25

Serum paraoxonase 1 (PON1) is a native lactonase capable of promiscuously hydrolyzing a broad range of substrates, including organophosphates, esters, and carbonates. Structurally, PON1 is a six-bladed β-propeller with a flexible loop (residues 70-81) covering the active site. This loop contains a functionally critical Tyr at position 71. We have performed detailed experimental and computational analyses of the role of selected Y71 variants in the active site stability and catalytic activity in order to probe the role of Y71 in PON1's lactonase and organophosphatase activities. We demonstrate that the impact of Y71 substitutions on PON1's lactonase activity is minimal, whereas the k cat for the paraoxonase activity is negatively perturbed by up to 100-fold, suggesting greater mutational robustness of the native activity. Additionally, while these substitutions modulate PON1's active site shape, volume, and loop flexibility, their largest effect is in altering the solvent accessibility of the active site by expanding the active site volume, allowing additional water molecules to enter. This effect is markedly more pronounced in the organophosphatase activity than the lactonase activity. Finally, a detailed comparison of PON1 to other organophosphatases demonstrates that either a similar "gating loop" or a highly buried solvent-excluding active site is a common feature of these enzymes. We therefore posit that modulating the active site hydrophobicity is a key element in facilitating the evolution of organophosphatase activity. This provides a concrete feature that can be utilized in the rational design of next-generation organophosphate hydrolases that are capable of selecting a specific reaction from a pool of viable substrates.

Exposure to fall hazards and safety climate in the aircraft maintenance industry.

PubMed

Neitzel, Richard L; Seixas, Noah S; Harris, Michael J; Camp, Janice

2008-01-01

Falls represent a significant occupational hazard, particularly in industries with dynamic work environments. This paper describes rates of noncompliance with fall hazard prevention requirements, perceived safety climate and worker knowledge and beliefs, and the association between fall exposure and safety climate measures in commercial aircraft maintenance activities. Walkthrough observations were conducted on aircraft mechanics at two participating facilities (Sites A and B) to ascertain the degree of noncompliance. Mechanics at each site completed questionnaires concerning fall hazard knowledge, personal safety beliefs, and safety climate. Questionnaire results were summarized into safety climate and belief scores by workgroup and site. Noncompliance rates observed during walkthroughs were compared to the climate-belief scores, and were expected to be inversely associated. Important differences were seen in fall safety performance between the sites. The study provided a characterization of aircraft maintenance fall hazards, and also demonstrated the effectiveness of an objective hazard assessment methodology. Noncompliance varied by height, equipment used, location of work on the aircraft, shift, and by safety system. Although the expected relationship between safety climate and noncompliance was seen for site-average climate scores, workgroups with higher safety climate scores had greater observed noncompliance within Site A. Overall, use of engineered safety systems had a significant impact on working safely, while safety beliefs and climate also contributed, though inconsistently. The results of this study indicate that safety systems are very important in reducing noncompliance with fall protection requirements in aircraft maintenance facilities. Site-level fall safety compliance was found to be related to safety climate, although an unexpected relationship between compliance and safety climate was seen at the workgroup level within site. Finally, observed fall safety compliance was found to differ from self-reported compliance.

Transverse colon cancer occurring at a colostomy site 35 years after colostomy: a case report.

PubMed

Maeda, Chiyo; Hidaka, Eiji; Shimada, Mari; Shimada, Shoji; Nakahara, Kenta; Takayanagi, Daisuke; Takehara, Yusuke; Mukai, Shumpei; Sawada, Naruhiko; Ishida, Fumio; Kudo, Shin-ei

2015-05-06

Carcinomas occurring at colostomy sites are rare, and most of these are metachronous colorectal cancers. The median time between colostomy and development of a carcinoma at a colostomy site is 22 years, which exceeds the length of the recommended follow-up period. We report a rare case of a carcinoma of the transverse colon occurring at a colostomy site in a patient without a history of colorectal cancer. An 89-year-old woman presented with a tumor occurring at a colostomy site. Thirty-five years previously, she had undergone a transverse loop colostomy for an iatrogenic colon perforation that occurred during left ureteral lithotomy. Upon physical examination, the patient had a hard nodule measuring 3 cm at the colostomy site. A biopsy of the nodule suggested adenocarcinoma, and the preoperative diagnosis was transverse colon cancer. A laparotomy was performed via a peristomal incision with 5-mm skin margins, and the tumor was covered by a surgical glove to avoid any tumor seeding. The colon was separated from the tumor by 5-cm margins, and the specimen was removed en bloc. An end colostomy was constructed to a new site on the right side of the abdomen. The deficit in the abdominal wall was repaired, and the skin was closed via a purse-string suture. The final diagnosis of the stoma tumor was transverse colon cancer (T2, N0, M0, stage I). One year and five months after surgery, there was no evidence of recurrence. The occurrence of carcinomas at colostomy sites in patients without a history of colorectal cancer is rare. It is important to train ostomates to monitor the stoma for possible tumor recurrence.

[Estuary health assessment using a benthic-index of biotic integrity in Yangtze Estuary and its adjacent waters].

PubMed

Zhou, Xiao-wei; Wang, Li-ping; Zheng, Bing-hui; Liu, Lu-san; Fu, Qing

2009-01-01

A benthic index of biotic integrity (B-IBI) was developed for application in estuaries health assessment of the Yangtze Estuary and its adjacent waters. Benthic macro-invertebrate samples were collected from 41 stream sites (13 non-degraded stations and 28 degraded stations) in the Yangtze Estuary and its adjacent waters in July, 2005. The analyses of the range of index value distribution, Pearson correlation and judgment ability were performed on fourteen candidate metrics. Six biological metrics were selected for the establishment of B-IBI, which were Shannon-Wiener index, the species number, total density, total biomass, Carapace Animals density percentage and Echinoderms density percentage. B-IBI was obtained by sum up all these indices after which were transformed into a uniform score by using the ratio scoring method. Base on 50 percentile of B-IBI value in reference sites, the criteria of health ranking was determined. The proposed criteria of benthic-index of biotic integrity were as follows: B-IBI > 2.48 was regarded as health, 1.86-2.48 sub-health, 1.24-1.86 fair, 0.62-1.24 poor, and B-IBI < 0.62 very poor. Assessing with these criteria, the results showed that among the 41 sites in Yangtze Estuary and its adjacent waters, 7 sites were health, 2 sites were sub-health, 8 sites were fair, 8 sites were poor and 16 sites were very poor. An independent data set sampled in June of 2006 was used to validate the index, the results indicated that final combined index correctly classified 89% of stations in the validation data set.

An integrated multi criteria approach for landfill siting in a conflicting environmental, economical and socio-cultural area.

PubMed

Eskandari, Mahnaz; Homaee, Mehdi; Mahmodi, Shahla

2012-08-01

Landfill site selection is a complicated multi criteria land use planning that should convince all related stakeholders with different insights. This paper addresses an integrating approach for landfill siting based on conflicting opinions among environmental, economical and socio-cultural expertise. In order to gain optimized siting decision, the issue was investigated in different viewpoints. At first step based on opinion sampling and questionnaire results of 35 experts familiar with local situations, the national environmental legislations and international practices, 13 constraints and 15 factors were built in hierarchical structure. Factors divided into three environmental, economical and socio-cultural groups. In the next step, the GIS-database was developed based on the designated criteria. In the third stage, the criteria standardization and criteria weighting were accomplished. The relative importance weights of criteria and subcriteria were estimated, respectively, using analytical hierarchy process and rank ordering methods based on different experts opinions. Thereafter, by using simple additive weighting method, the suitability maps for landfill siting in Marvdasht, Iran, was evaluated in environmental, economical and socio-cultural visions. The importance of each group of criteria in its own vision was assigned to be higher than two other groups. In the fourth stage, the final suitability map was obtained after crossing three resulted maps in different visions and reported in five suitability classes for landfill construction. This map indicated that almost 1224 ha of the study area can be considered as best suitable class for landfill siting considering all visions. In the last stage, a comprehensive field visit was performed to verify the selected site obtained from the proposed model. This field inspection has confirmed the proposed integrating approach for the landfill siting. Copyright © 2012 Elsevier Ltd. All rights reserved.

Predicting on-site environmental impacts of municipal engineering works

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gangolells, Marta, E-mail: marta.gangolells@upc.edu; Casals, Miquel, E-mail: miquel.casals@upc.edu; Forcada, Núria, E-mail: nuria.forcada@upc.edu

2014-01-15

The research findings fill a gap in the body of knowledge by presenting an effective way to evaluate the significance of on-site environmental impacts of municipal engineering works prior to the construction stage. First, 42 on-site environmental impacts of municipal engineering works were identified by means of a process-oriented approach. Then, 46 indicators and their corresponding significance limits were determined on the basis of a statistical analysis of 25 new-build and remodelling municipal engineering projects. In order to ensure the objectivity of the assessment process, direct and indirect indicators were always based on quantitative data from the municipal engineering projectmore » documents. Finally, two case studies were analysed and found to illustrate the practical use of the proposed model. The model highlights the significant environmental impacts of a particular municipal engineering project prior to the construction stage. Consequently, preventive actions can be planned and implemented during on-site activities. The results of the model also allow a comparison of proposed municipal engineering projects and alternatives with respect to the overall on-site environmental impact and the absolute importance of a particular environmental aspect. These findings are useful within the framework of the environmental impact assessment process, as they help to improve the identification and evaluation of on-site environmental aspects of municipal engineering works. The findings may also be of use to construction companies that are willing to implement an environmental management system or simply wish to improve on-site environmental performance in municipal engineering projects. -- Highlights: • We present a model to predict the environmental impacts of municipal engineering works. • It highlights significant on-site environmental impacts prior to the construction stage. • Findings are useful within the environmental impact assessment process. • They also help contractors to implement environmental management systems.« less

78 FR 760 - Notice of Availability of the Final General Management Plan/Final Environmental Impact Statement...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-04

... document is available on the internet at the NPS Planning, Environment, and Public Comment Web site at http.../EIS assesses impacts to soil resources, water quality, soundscapes, vegetation and wildlife...

A transition to laparoendoscopic single-site surgery (LESS) radical prostatectomy: human cadaver experimental and initial clinical experience.

PubMed

Barret, Eric; Sanchez-Salas, Rafael; Kasraeian, Ali; Benoist, Nicolas; Ganatra, Anjali; Cathelineau, Xavier; Rozet, Francois; Galiano, Marc; Vallancien, Guy

2009-01-01

Laparoendoscopic single-site surgery (LESS) represents a novel approach to abdominal surgery. Several applications have already been described. Drawbacks include limited range of motion and need for articulated instruments. Robotic technology could overcome such technical difficulties. We report our experience with LESS radical prostatectomy (LESS-RP) in a cadaver and LESS robot-assisted radical prostatectomy (LESS-RARP) in a human patient. Standard laparoscopic instruments (SLI) and articulated laparoscopic instruments were used in the cadaveric LESS-RP. The da Vinci system was used in the LESS-RARP. Both procedures reproduced standard extraperitoneal laparoscopic prostatectomy as performed at Institut Montsouris. Control of the dorsal venous complex (DVC) and urethrovesical anastomosis (UVA) were key elements evaluated for feasibility. Cadaveric model: Total operative time (TOT) was 160 minutes, with 5 minutes for the DVC (one stitch) and 35 minutes for the UVA (six stitches). Although articulated instruments were helpful in the operation, SLI remained essential for the procedure. Clinical experience: LESS-RARP was performed for T(1c) prostate cancer. TOT was 150 minutes, including 5 minutes for the DVC (one figure-of-eight stitch) and 30 minutes for the UVA (six interrupted stitches). Blood loss was 500 mL. Bilateral neurovascular preservation was performed, and results of final pathologic examination showed negative surgical margins. The human cadaver is an adequate model for LESS-RP, and LESS-RARP is feasible to be performed in the clinical arena. The synergy of robotic technology and LESS represents a new generation of surgery.

78 FR 8582 - Final Environmental Impact Statement for Brooks River Visitor Access for Katmai National Park and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

... River floating bridge and sites to relocate the existing Naknek Lake barge landing area at the mouth of... barge landing site would be located approximately 200 feet south of the mouth of the Brooks River. A new... new Naknek Lake barge landing site. Alternative 4 (NPS Preferred Alternative): This alternative...

77 FR 58443 - Migratory Bird Hunting; Final Frameworks for Late-Season Migratory Bird Hunting Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-20

... address above, or from the Division of Migratory Bird Management's Web site at http://www.fws.gov... INFORMATION CONTACT or from our Web site at http://www.fws.gov/migratorybirds . Review of Public Comments and... http://www.regulations.gov , or from our Web site at http://www.fws.gov/migratorybirds/NewReports...

Cannon Air Force base New Mexico, Installation of Digital Airport Surveillance Radar, Final Environmental Assessment

DTIC Science & Technology

2005-07-06

C95.1-1991, American National Standard Safety Levels With Respect to Human Exposure to Radiofrequency Electromagnetic Fields , 300 kHz to 100 GHz. New...Site 4) were evaluated for possible siting of the ASR- 11. All three sites are situated in undeveloped fields on base. Site 2 is located between the...alternative ASR-1 1 sites. 3.12 ELECTROMAGNETIC ENERGY 3.12.1 Existing Conditions Electrical currents and components generate electrical fields and

Manned versus unmanned rendezvous and capture

NASA Technical Reports Server (NTRS)

Brody, Adam R.

1991-01-01

Rendezvous and capture (docking) operations may be performed either automatically or under manual control. In cases where humans are far from the mission site, or high-bandwidth communications lines are not in place, automation is the only option. Such might be the case with unmanned missions to the moon or Mars that involve orbital docking or cargo transfer. In crewed situations where sensors, computation capabilities, and other necessary instrumentation are unavailable, manual control is the only alternative. Power, mass, cost, or other restrictions may limit the availability of the machinery required for an automated rendezvous and capture. The only occasions for which there is a choice about whether to use automated or manual control are those where the vehicle(s) have both the crew and instrumentation necessary to perform the mission either way. The following discussion will focus on the final approach or capture (docking) maneuver. The maneuvers required for long-range rendezvous operations are calculated by computers. It is almost irrelevant whether it is an astronaut, watching a count-down timer who pushes the button firing the thruster or whether the computer keeps track of the time and fires with the astronaut monitoring. The actual manual workload associated with a mission that may take as long as hours or days to perform is small. The workload per unit time increases tremendously during the final approach (docking) phase and this is where the issue of manual versus automatic is more important.

Final Hazard Categorization and Auditable Safety Analysis for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2 and 118-H-3 Solid Waste Burial Grounds

DOE Office of Scientific and Technical Information (OSTI.GOV)

T. J. Rodovsky

2006-03-01

This report presents the initial hazard categorization, final hazard categorization and auditable safety analysis for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

Data Validation Package September 2016 Groundwater and Surface Water Sampling at the Slick Rock, Colorado, Processing Sites January 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Traub, David; Nguyen, Jason

The Slick Rock, Colorado, Processing Sites are referred to as the Slick Rock West Processing Site (SRK05) and the Slick Rock East Processing Site (SRK06). This annual event involved sampling both sites for a total of 16 monitoring wells and 6 surface water locations as required by the 2006 Draft Final Ground Water Compliance Action Plan for the Slick Rock, Colorado, Processing Sites (GCAP). A domestic well was also sampled at a property adjacent to the Slick Rock East site at the request of the landowner.

Integration of Geomatics Techniques for Digitizing Highly Relevant Geological and Cultural Heritage Sites: the Case of San Leo (italy)

NASA Astrophysics Data System (ADS)

Girelli, V. A.; Borgatti, L.; Dellapasqua, M.; Mandanici, E.; Spreafico, M. C.; Tini, M. A.; Bitelli, G.

2017-08-01

The research activities described in this contribution were carried out at San Leo (Italy). The town is located on the top of a quadrangular rock slab affected by a complex system of fractures and has a wealth of cultural heritage, as evidenced by the UNESCO's nomination. The management of this fragile set requires a comprehensive system of geometrical information to analyse and preserve all the geological and cultural features. In this perspective, the latest Geomatics techniques were used to perform some detailed surveys and to manage the great amount of acquired geometrical knowledge of both natural (the cliff) and historical heritage. All the data were also georeferenced in a unique reference system. In particular, high accurate terrestrial laser scanner surveys were performed for the whole cliff, in order to obtain a dense point cloud useful for a large number of geological studies, among others the analyses of the last rockslide by comparing pre- and post-event data. Moreover, the geometrical representation of the historical centre was performed using different approaches, in order to generate an accurate DTM and DSM of the site. For these purposes, a large scale numerical map was used, integrating the data with GNSS and laser surveys of the area. Finally, many surveys were performed with different approaches on some of the most relevant monuments of the town. In fact, these surveys were performed by terrestrial laser scanner, light structured scanner and photogrammetry, the last mainly applied with the Structure from Motion approach.

Evaluation of depleted uranium in the environment at Aberdeen Proving Grounds, Maryland and Yuma Proving Grounds, Arizona. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kennedy, P.L.; Clements, W.H.; Myers, O.B.

1995-01-01

This report represents an evaluation of depleted uranium (DU) introduced into the environment at the Aberdeen Proving Grounds (APG), Maryland and Yuma Proving Grounds (YPG) Arizona. This was a cooperative project between the Environmental Sciences and Statistical Analyses Groups at LANL and with the Department of Fishery and Wildlife Biology at Colorado State University. The project represents a unique approach to assessing the environmental impact of DU in two dissimilar ecosystems. Ecological exposure models were created for each ecosystem and sensitivity/uncertainty analyses were conducted to identify exposure pathways which were most influential in the fate and transport of DU inmore » the environment. Research included field sampling, field exposure experiment, and laboratory experiments. The first section addresses DU at the APG site. Chapter topics include bioenergetics-based food web model; field exposure experiments; bioconcentration by phytoplankton and the toxicity of U to zooplankton; physical processes governing the desorption of uranium from sediment to water; transfer of uranium from sediment to benthic invertebrates; spead of adsorpion by benthic invertebrates; uptake of uranium by fish. The final section of the report addresses DU at the YPG site. Chapters include the following information: Du transport processes and pathway model; field studies of performance of exposure model; uptake and elimination rates for kangaroo rates; chemical toxicity in kangaroo rat kidneys.« less

Glacial-Interglacial, Orbital and Millennial-Scale Climate Variability for the Last Glacial Cycle at Shackleton Site U1385 based on Dinoflagellate Cysts

NASA Astrophysics Data System (ADS)

Datema, M.

2015-12-01

The Shackleton Site (IODP Expedition 339 Site U1385), located off the West-Portuguese Margin, preserves a continuous high-fidelity record of millennial-scale climate variability for the last several glacial cycles (~1.4 Myr) that can be correlated precisely to patterns observed in polar ice cores. In addition, rapid delivery of terrestrial material to the deep-sea environment allows the correlation of these marine records to European terrestrial climate records. This unique marine-ice-terrestrial linkage makes the Shackleton Site the ideal reference section for studying Quaternary abrupt climate change. The main objective of studying Site U1385 is to establish a marine reference section of Pleistocene climate change. We generated (sub)millennial-scale (~600 year interval) dinoflagellate cyst (dinocyst) assemblage records from Shackleton Site U1385 (IODP Expedition 339) to reconstruct sea surface temperature (SST) and productivity/upwelling over the last 152 kyrs. In addition, our approach allows for detailed land-sea correlations, because we also counted assemblages of pollen and spores from higher plants. Dinocyst SST and upwelling proxies, as well as warm/cold pollen proxies from Site U1385 show glacial-interglacial, orbital and stadial-interstadial climate variability and correlate very well to Uk'37, planktic foraminifer δ18O and Ca/Ti proxies of previously drilled Shackleton Sites and Greenland Ice Core δ18O. The palynological proxies capture (almost) all Dansgaard-Oeschger events of the last glacial cycle, also before ~70 ka, where millennial-scale variability is overprinted by precession. We compare the performance and results of the palynology of Site U1385 to proxies of previously drilled Shackleton Sites and conclude that palynology strengthens the potential of this site to form a multi-proxy reference section for millennial scale climate variability across the Pleistocene-Holocene. Finally, we will present a long-term paleoceanographic perspective down to ~150 ka.

Contained rocket motor burn demonstrations in X-tunnel: Final report for the DoD/DOE Joint Demilitarization Technology Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

S. W. Allendorf; B. W. Bellow; R. f. Boehm

Three low-pressure rocket motor propellant burn tests were performed in a large, sealed test chamber located at the X-tunnel complex on the Department of Energy's Nevada Test Site in the period May--June 1997. NIKE rocket motors containing double base propellant were used in two tests (two and four motors, respectively), and the third test used two improved HAWK rocket motors containing composite propellant. The preliminary containment safety calculations, the crack and burn procedures used in each test, and the results of various measurements made during and after each test are all summarized and collected in this document.

American Recovery and Reinvestment Act (ARRA) - FEMP Technical Assistance - Federal Aviation Administration - Project 209 - Control Tower and Support Building, Boise, Idaho

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arends, J.; Sandusky, William F.

2010-06-28

This report documents an energy audit performed by Pacific Northwest National Laboratory (PNNL) and Redhorse Corporation (Redhorse) conducted on the Federal Aviation Administration (FAA) control tower and base building in Boise, Idaho. This report presents findings of the energy audit team that evaluated construction documents and operating specifications (at the 100% level) followed by a site visit of the facility under construction. The focus of the review was to identify measures that could be incorporated into the final design and operating specifications that would result in additional energy savings for FAA that would not have otherwise occurred.

Photogrammetric Archaeological Survey with UAV

NASA Astrophysics Data System (ADS)

Mouget, A.; Lucet, G.

2014-05-01

This document describes a way to obtain various photogrammetric products from aerial photograph using a drone. The aim of the project was to develop a methodology to obtain information for the study of the architecture of pre-Columbian archaeological sites in Mexico combining the manoeuvrability and low cost of a drone with the accuracy of the results of the open source photogrammetric MicMac software. It presents the UAV and the camera used, explains how to manipulate it to carry out stereoscopic photographs, the flight and camera parameters chosen, the treatments performed to obtain orthophotos and 3D models with a centimetric resolution, and finally outlines the quality of the results.

The population structure and recent colonization history of Oregon threespine stickleback determined using restriction-site associated DNA-sequencing.

PubMed

Catchen, Julian; Bassham, Susan; Wilson, Taylor; Currey, Mark; O'Brien, Conor; Yeates, Quick; Cresko, William A

2013-06-01

Understanding how genetic variation is partitioned across genomes within and among populations is a fundamental problem in ecological and evolutionary genetics. To address this problem, we studied the threespine stickleback fish, which has repeatedly undergone parallel phenotypic and genetic differentiation when oceanic fish have invaded freshwater habitats. While significant evolutionary genetic research has been performed using stickleback from geographic regions that have been deglaciated in the last 20 000 years, less research has focused on freshwater populations that predate the last glacial maximum. We performed restriction-site associated DNA-sequencing (RAD-seq) based population genomic analyses on stickleback from across Oregon, which was not glaciated during the last maximum. We sampled stickleback from coastal, Willamette Basin and central Oregon sites, analysed their genetic diversity using RAD-seq, performed structure analyses, reconstructed their phylogeographic history and tested the hypothesis of recent stickleback introduction into central Oregon, where incidence of this species was only recently documented. Our results showed a clear phylogeographic break between coastal and inland populations, with oceanic populations exhibiting the lowest levels of divergence from one another. Willamette Basin and central Oregon populations formed a clade of closely related populations, a finding consistent with a recent introduction of stickleback into central Oregon. Finally, genome-wide analysis of genetic diversity (π) and correlations of alleles within individuals in subpopulations (FIS) supported a role for introgressive hybridization in coastal populations and a recent expansion in central Oregon. Our results exhibit the power of next-generation sequencing genomic approaches such as RAD-seq to identify both historical population structure and recent colonization history. © 2013 John Wiley & Sons Ltd.

Seismic hazard assessment of the Province of Murcia (SE Spain): analysis of source contribution to hazard

NASA Astrophysics Data System (ADS)

García-Mayordomo, J.; Gaspar-Escribano, J. M.; Benito, B.

2007-10-01

A probabilistic seismic hazard assessment of the Province of Murcia in terms of peak ground acceleration (PGA) and spectral accelerations [SA( T)] is presented in this paper. In contrast to most of the previous studies in the region, which were performed for PGA making use of intensity-to-PGA relationships, hazard is here calculated in terms of magnitude and using European spectral ground-motion models. Moreover, we have considered the most important faults in the region as specific seismic sources, and also comprehensively reviewed the earthquake catalogue. Hazard calculations are performed following the Probabilistic Seismic Hazard Assessment (PSHA) methodology using a logic tree, which accounts for three different seismic source zonings and three different ground-motion models. Hazard maps in terms of PGA and SA(0.1, 0.2, 0.5, 1.0 and 2.0 s) and coefficient of variation (COV) for the 475-year return period are shown. Subsequent analysis is focused on three sites of the province, namely, the cities of Murcia, Lorca and Cartagena, which are important industrial and tourism centres. Results at these sites have been analysed to evaluate the influence of the different input options. The most important factor affecting the results is the choice of the attenuation relationship, whereas the influence of the selected seismic source zonings appears strongly site dependant. Finally, we have performed an analysis of source contribution to hazard at each of these cities to provide preliminary guidance in devising specific risk scenarios. We have found that local source zones control the hazard for PGA and SA( T ≤ 1.0 s), although contribution from specific fault sources and long-distance north Algerian sources becomes significant from SA(0.5 s) onwards.

Detecting ecosystem performance anomalies for land management in the upper colorado river basin using satellite observations, climate data, and ecosystem models

USGS Publications Warehouse

Gu, Yingxin; Wylie, B.K.

2010-01-01

This study identifies areas with ecosystem performance anomalies (EPA) within the Upper Colorado River Basin (UCRB) during 2005-2007 using satellite observations, climate data, and ecosystem models. The final EPA maps with 250-m spatial resolution were categorized as normal performance, underperformance, and overperformance (observed performance relative to weather-based predictions) at the 90% level of confidence. The EPA maps were validated using "percentage of bare soil" ground observations. The validation results at locations with comparable site potential showed that regions identified as persistently underperforming (overperforming) tended to have a higher (lower) percentage of bare soil, suggesting that our preliminary EPA maps are reliable and agree with ground-based observations. The 3-year (2005-2007) persistent EPA map from this study provides the first quantitative evaluation of ecosystem performance anomalies within the UCRB and will help the Bureau of Land Management (BLM) identify potentially degraded lands. Results from this study can be used as a prototype by BLM and other land managers for making optimal land management decisions. ?? 2010 by the authors.

Detecting Ecosystem Performance Anomalies for Land Management in the Upper Colorado River Basin Using Satellite Observations, Climate Data, and Ecosystem Models

USGS Publications Warehouse

Gu, Yingxin; Wylie, Bruce K.

2010-01-01

This study identifies areas with ecosystem performance anomalies (EPA) within the Upper Colorado River Basin (UCRB) during 2005–2007 using satellite observations, climate data, and ecosystem models. The final EPA maps with 250-m spatial resolution were categorized as normal performance, underperformance, and overperformance (observed performance relative to weather-based predictions) at the 90% level of confidence. The EPA maps were validated using “percentage of bare soil” ground observations. The validation results at locations with comparable site potential showed that regions identified as persistently underperforming (overperforming) tended to have a higher (lower) percentage of bare soil, suggesting that our preliminary EPA maps are reliable and agree with ground-based observations. The 3-year (2005–2007) persistent EPA map from this study provides the first quantitative evaluation of ecosystem performance anomalies within the UCRB and will help the Bureau of Land Management (BLM) identify potentially degraded lands. Results from this study can be used as a prototype by BLM and other land managers for making optimal land management decisions.

3D reconstruction of the final PHILAE landing site: Abydos

NASA Astrophysics Data System (ADS)

Capanna, Claire; Jorda, Laurent; Lamy, Philippe; Gesquière, Gilles; Delmas, Cédric; Durand, Joëlle; Gaudon, Philippe; Jurado, Eric

2015-11-01

The Abydos region is the region of the final landing site of the PHILAE lander. The landing site has been potentially identified on images of this region acquired by the OSIRIS imaging system aboard the orbiter before (Oct 22, 2014) and after (Dec 6-13, 2014) the landing of PHILAE (Lamy et al., in prep.). Assuming that this identification is correct, we reconstructed the topography of Abydos in 3D using a method called ``multiresolution photoclinometry by deformation'' (MPCD, Capanna et al., The Visual Computer, 29(6-8): 825-835, 2013). The method works in two steps: (a) a DTM of this region is extracted from the global MPCD shape model, (b) the resulting triangular mesh is progressively deformed at increasing spatial resolution in order to match a set of 14 images of Abydos at pixel resolutions between 1 and 8 m. The method used to perform the image matching is the L-BFGS-b non-linear optimization (Morales et al., ACM Trans. Math. Softw., 38(1): 1-4, 2011).In spite of the very unfavourable illumination conditions, we achieve a vertical accuracy of about 3 m, while the horizontal sampling is 0.5 m. The accuracy is limited by high incidence angles on the images (about 60 deg on average) combined with a complex topography including numerous cliffs and a few overhangs. We also check the compatibility of the local DTM with the images obtained by the CIVA-P instrument aboard PHILAE. If the Lamy et al. identification is correct, our DTM shows that PHILAE landed in a cavity at the bottom of a small cliff of 8 m height.

Advanced wind turbine near-term product development. Final technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1996-01-01

In 1990 the US Department of Energy initiated the Advanced Wind Turbine (AWT) Program to assist the growth of a viable wind energy industry in the US. This program, which has been managed through the National Renewable Energy Laboratory (NREL) in Golden, Colorado, has been divided into three phases: (1) conceptual design studies, (2) near-term product development, and (3) next-generation product development. The goals of the second phase were to bring into production wind turbines which would meet the cost goal of $0.05 kWh at a site with a mean (Rayleigh) windspeed of 5.8 m/s (13 mph) and a verticalmore » wind shear exponent of 0.14. These machines were to allow a US-based industry to compete domestically with other sources of energy and to provide internationally competitive products. Information is given in the report on design values of peak loads and of fatigue spectra and the results of the design process are summarized in a table. Measured response is compared with the results from mathematical modeling using the ADAMS code and is discussed. Detailed information is presented on the estimated costs of maintenance and on spare parts requirements. A failure modes and effects analysis was carried out and resulted in approximately 50 design changes including the identification of ten previously unidentified failure modes. The performance results of both prototypes are examined and adjusted for air density and for correlation between the anemometer site and the turbine location. The anticipated energy production at the reference site specified by NREL is used to calculate the final cost of energy using the formulas indicated in the Statement of Work. The value obtained is $0.0514/kWh in January 1994 dollars. 71 figs., 30 tabs.« less

Ensemble predictive model for more accurate soil organic carbon spectroscopic estimation

NASA Astrophysics Data System (ADS)

Vašát, Radim; Kodešová, Radka; Borůvka, Luboš

2017-07-01

A myriad of signal pre-processing strategies and multivariate calibration techniques has been explored in attempt to improve the spectroscopic prediction of soil organic carbon (SOC) over the last few decades. Therefore, to come up with a novel, more powerful, and accurate predictive approach to beat the rank becomes a challenging task. However, there may be a way, so that combine several individual predictions into a single final one (according to ensemble learning theory). As this approach performs best when combining in nature different predictive algorithms that are calibrated with structurally different predictor variables, we tested predictors of two different kinds: 1) reflectance values (or transforms) at each wavelength and 2) absorption feature parameters. Consequently we applied four different calibration techniques, two per each type of predictors: a) partial least squares regression and support vector machines for type 1, and b) multiple linear regression and random forest for type 2. The weights to be assigned to individual predictions within the ensemble model (constructed as a weighted average) were determined by an automated procedure that ensured the best solution among all possible was selected. The approach was tested at soil samples taken from surface horizon of four sites differing in the prevailing soil units. By employing the ensemble predictive model the prediction accuracy of SOC improved at all four sites. The coefficient of determination in cross-validation (R2cv) increased from 0.849, 0.611, 0.811 and 0.644 (the best individual predictions) to 0.864, 0.650, 0.824 and 0.698 for Site 1, 2, 3 and 4, respectively. Generally, the ensemble model affected the final prediction so that the maximal deviations of predicted vs. observed values of the individual predictions were reduced, and thus the correlation cloud became thinner as desired.

Multi-focal multiphoton lithography.

PubMed

Ritschdorff, Eric T; Nielson, Rex; Shear, Jason B

2012-03-07

Multiphoton lithography (MPL) provides unparalleled capabilities for creating high-resolution, three-dimensional (3D) materials from a broad spectrum of building blocks and with few limitations on geometry, qualities that have been key to the design of chemically, mechanically, and biologically functional microforms. Unfortunately, the reliance of MPL on laser scanning limits the speed at which fabrication can be performed, making it impractical in many instances to produce large-scale, high-resolution objects such as complex micromachines, 3D microfluidics, etc. Previously, others have demonstrated the possibility of using multiple laser foci to simultaneously perform MPL at numerous sites in parallel, but use of a stage-scanning system to specify fabrication coordinates resulted in the production of identical features at each focal position. As a more general solution to the bottleneck problem, we demonstrate here the feasibility for performing multi-focal MPL using a dynamic mask to differentially modulate foci, an approach that enables each fabrication site to create independent (uncorrelated) features within a larger, integrated microform. In this proof-of-concept study, two simultaneously scanned foci produced the expected two-fold decrease in fabrication time, and this approach could be readily extended to many scanning foci by using a more powerful laser. Finally, we show that use of multiple foci in MPL can be exploited to assign heterogeneous properties (such as differential swelling) to micromaterials at distinct positions within a fabrication zone.

Prediction of Protein-Protein Interaction Sites with Machine-Learning-Based Data-Cleaning and Post-Filtering Procedures.

PubMed

Liu, Guang-Hui; Shen, Hong-Bin; Yu, Dong-Jun

2016-04-01

Accurately predicting protein-protein interaction sites (PPIs) is currently a hot topic because it has been demonstrated to be very useful for understanding disease mechanisms and designing drugs. Machine-learning-based computational approaches have been broadly utilized and demonstrated to be useful for PPI prediction. However, directly applying traditional machine learning algorithms, which often assume that samples in different classes are balanced, often leads to poor performance because of the severe class imbalance that exists in the PPI prediction problem. In this study, we propose a novel method for improving PPI prediction performance by relieving the severity of class imbalance using a data-cleaning procedure and reducing predicted false positives with a post-filtering procedure: First, a machine-learning-based data-cleaning procedure is applied to remove those marginal targets, which may potentially have a negative effect on training a model with a clear classification boundary, from the majority samples to relieve the severity of class imbalance in the original training dataset; then, a prediction model is trained on the cleaned dataset; finally, an effective post-filtering procedure is further used to reduce potential false positive predictions. Stringent cross-validation and independent validation tests on benchmark datasets demonstrated the efficacy of the proposed method, which exhibits highly competitive performance compared with existing state-of-the-art sequence-based PPIs predictors and should supplement existing PPI prediction methods.

System efficiency of a tap transformer based grid connection topology applied on a direct driven generator for wind power.

PubMed

Apelfröjd, Senad; Eriksson, Sandra

2014-01-01

Results from experiments on a tap transformer based grid connection system for a variable speed vertical axis wind turbine are presented. The tap transformer based system topology consists of a passive diode rectifier, DC-link, IGBT inverter, LCL-filter, and tap transformer. Full range variable speed operation is enabled by using the different step-up ratios of a tap transformer. Simulations using MATLAB/Simulink have been performed in order to study the behavior of the system. A full experimental set up of the system has been used in the laboratory study, where a clone of the on-site generator was driven by an induction motor and the system was connected to a resistive load to better evaluate the performance. Furthermore, the system is run and evaluated for realistic wind speeds and variable speed operation. For a more complete picture of the system performance, a case study using real site Weibull parameters is done, comparing different tap selection options. The results show high system efficiency at nominal power and an increase in overall power output for full tap operation in comparison with the base case, a standard transformer. In addition, the loss distribution at different wind speeds is shown, which highlights the dominant losses at low and high wind speeds. Finally, means for further increasing the overall system efficiency are proposed.

System Efficiency of a Tap Transformer Based Grid Connection Topology Applied on a Direct Driven Generator for Wind Power

PubMed Central

2014-01-01

Results from experiments on a tap transformer based grid connection system for a variable speed vertical axis wind turbine are presented. The tap transformer based system topology consists of a passive diode rectifier, DC-link, IGBT inverter, LCL-filter, and tap transformer. Full range variable speed operation is enabled by using the different step-up ratios of a tap transformer. Simulations using MATLAB/Simulink have been performed in order to study the behavior of the system. A full experimental set up of the system has been used in the laboratory study, where a clone of the on-site generator was driven by an induction motor and the system was connected to a resistive load to better evaluate the performance. Furthermore, the system is run and evaluated for realistic wind speeds and variable speed operation. For a more complete picture of the system performance, a case study using real site Weibull parameters is done, comparing different tap selection options. The results show high system efficiency at nominal power and an increase in overall power output for full tap operation in comparison with the base case, a standard transformer. In addition, the loss distribution at different wind speeds is shown, which highlights the dominant losses at low and high wind speeds. Finally, means for further increasing the overall system efficiency are proposed. PMID:25258733

Integrated biodepuration of pesticide-contaminated wastewaters from the fruit-packaging industry using biobeds: Bioaugmentation, risk assessment and optimized management.

PubMed

Karas, Panagiotis A; Perruchon, Chiara; Karanasios, Evangelos; Papadopoulou, Evangelia S; Manthou, Elena; Sitra, Stefania; Ehaliotis, Constantinos; Karpouzas, Dimitrios G

2016-12-15

Wastewaters from fruit-packaging plants contain high loads of toxic and persistent pesticides and should be treated on site. We evaluated the depuration performance of five pilot biobeds against those effluents. In addition we tested bioaugmentation with bacterial inocula as a strategy for optimization of their depuration capacity. Finally we determined the composition and functional dynamics of the microbial community via q-PCR. Practical issues were also addressed including the risk associated with the direct environmental disposal of biobed-treated effluents and decontamination methods for the spent packing material. Biobeds showed high depuration capacity (>99.5%) against all pesticides with bioaugmentation maximizing their depuration performance against the persistent fungicide thiabendazole (TBZ). This was followed by a significant increase in the abundance of bacteria, fungi and of catabolic genes of aromatic compounds catA and pcaH. Bioaugmentation was the most potent decontamination method for spent packing material with composting being an effective alternative. Risk assessment based on practical scenarios (pome and citrus fruit-packaging plants) and the depuration performance of the pilot biobeds showed that discharge of the treated effluents into an 0.1-ha disposal site did not entail an environmental risk, except for TBZ-containing effluents where a larger disposal area (0.2ha) or bioaugmentation alleviated the risk. Copyright © 2016 Elsevier B.V. All rights reserved.

Integral Analysis of Seismic Refraction and Ambient Vibration Survey for Subsurface Profile Evaluation

NASA Astrophysics Data System (ADS)

Hazreek, Z. A. M.; Kamarudin, A. F.; Rosli, S.; Fauziah, A.; Akmal, M. A. K.; Aziman, M.; Azhar, A. T. S.; Ashraf, M. I. M.; Shaylinda, M. Z. N.; Rais, Y.; Ishak, M. F.; Alel, M. N. A.

2018-04-01

Geotechnical site investigation as known as subsurface profile evaluation is the process of subsurface layer characteristics determination which finally used for design and construction phase. Traditionally, site investigation was performed using drilling technique thus suffers from several limitation due to cost, time, data coverage and sustainability. In order to overcome those problems, this study adopted surface techniques using seismic refraction and ambient vibration method for subsurface profile depth evaluation. Seismic refraction data acquisition and processing was performed using ABEM Terraloc and OPTIM software respectively. Meanwhile ambient vibration data acquisition and processing was performed using CityShark II, Lennartz and GEOPSY software respectively. It was found that studied area consist of two layers representing overburden and bedrock geomaterials based on p-wave velocity value (vp = 300 – 2500 m/s and vp > 2500 m/s) and natural frequency value (Fo = 3.37 – 3.90 Hz) analyzed. Further analysis found that both methods show some good similarity in term of depth and thickness with percentage accuracy at 60 – 97%. Consequently, this study has demonstrated that the application of seismic refractin and ambient vibration method was applicable in subsurface profile depth and thickness estimation. Moreover, surface technique which consider as non-destructive method adopted in this study was able to compliment conventional drilling method in term of cost, time, data coverage and environmental sustainaibility.

75 FR 27784 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-18

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort AGENCY: National Institute for Occupational Safety and Health... concerning the final effect of the decision to designate a class of employees from the Nevada Test Site as an...

Predicting carbon dioxide and energy fluxes across global FLUXNET sites with regression algorithms

DOE PAGES

Tramontana, Gianluca; Jung, Martin; Schwalm, Christopher R.; ...

2016-07-29

Spatio-temporal fields of land–atmosphere fluxes derived from data-driven models can complement simulations by process-based land surface models. While a number of strategies for empirical models with eddy-covariance flux data have been applied, a systematic intercomparison of these methods has been missing so far. In this study, we performed a cross-validation experiment for predicting carbon dioxide, latent heat, sensible heat and net radiation fluxes across different ecosystem types with 11 machine learning (ML) methods from four different classes (kernel methods, neural networks, tree methods, and regression splines). We applied two complementary setups: (1) 8-day average fluxes based on remotely sensed data andmore » (2) daily mean fluxes based on meteorological data and a mean seasonal cycle of remotely sensed variables. The patterns of predictions from different ML and experimental setups were highly consistent. There were systematic differences in performance among the fluxes, with the following ascending order: net ecosystem exchange ( R 2 < 0.5), ecosystem respiration ( R 2 > 0.6), gross primary production ( R 2> 0.7), latent heat ( R 2 > 0.7), sensible heat ( R 2 > 0.7), and net radiation ( R 2 > 0.8). The ML methods predicted the across-site variability and the mean seasonal cycle of the observed fluxes very well ( R 2 > 0.7), while the 8-day deviations from the mean seasonal cycle were not well predicted ( R 2 < 0.5). Fluxes were better predicted at forested and temperate climate sites than at sites in extreme climates or less represented by training data (e.g., the tropics). Finally, the evaluated large ensemble of ML-based models will be the basis of new global flux products.« less

Predicting RNA-protein binding sites and motifs through combining local and global deep convolutional neural networks.

PubMed

Pan, Xiaoyong; Shen, Hong-Bin

2018-05-02

RNA-binding proteins (RBPs) take over 5∼10% of the eukaryotic proteome and play key roles in many biological processes, e.g. gene regulation. Experimental detection of RBP binding sites is still time-intensive and high-costly. Instead, computational prediction of the RBP binding sites using pattern learned from existing annotation knowledge is a fast approach. From the biological point of view, the local structure context derived from local sequences will be recognized by specific RBPs. However, in computational modeling using deep learning, to our best knowledge, only global representations of entire RNA sequences are employed. So far, the local sequence information is ignored in the deep model construction process. In this study, we present a computational method iDeepE to predict RNA-protein binding sites from RNA sequences by combining global and local convolutional neural networks (CNNs). For the global CNN, we pad the RNA sequences into the same length. For the local CNN, we split a RNA sequence into multiple overlapping fixed-length subsequences, where each subsequence is a signal channel of the whole sequence. Next, we train deep CNNs for multiple subsequences and the padded sequences to learn high-level features, respectively. Finally, the outputs from local and global CNNs are combined to improve the prediction. iDeepE demonstrates a better performance over state-of-the-art methods on two large-scale datasets derived from CLIP-seq. We also find that the local CNN run 1.8 times faster than the global CNN with comparable performance when using GPUs. Our results show that iDeepE has captured experimentally verified binding motifs. https://github.com/xypan1232/iDeepE. xypan172436@gmail.com or hbshen@sjtu.edu.cn. Supplementary data are available at Bioinformatics online.

Final Report: Results of Environmental Site Investigation at Sylvan Grove, Kansas

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaFreniere, Lorraine M

Sylvan Grove is located in western Lincoln County, approximately 60 mi west of Salina, Kansas (Figure 1.1). From 1954 to 1966, the Commodity Credit Corporation (CCC), an agency of the U.S. Department of Agriculture (USDA), operated a grain storage facility at the northeastern edge of Sylvan Grove. During this time, commercial grain fumigants containing carbon tetrachloride were in common use to preserve grain in storage. In 1998, the Kansas Department of Health and Environment (KDHE) found carbon tetrachloride above the maximum contaminant level (MCL) of 5 μg/L in groundwater from one private well used for livestock and lawn and gardenmore » watering. The 1998 KDHE sampling at Sylvan Grove was conducted under the USDA private well sampling program. To determine whether the former CCC/USDA facility at Sylvan Grove is a potential contaminant source and its possible relationship to the contamination in groundwater, the CCC/USDA proposed to conduct an environmental site investigation, in accordance with the Intergovernmental Agreement between the KDHE and the Farm Service Agency (FSA) of the USDA. Argonne National Laboratory, on behalf of the CCC/USDA, developed a work plan (Argonne 2012) for the site investigation and a supplemental work plan for indoor and ambient air sampling (Appendix A). The proposed work was approved by the KDHE (2012a, 2013). The investigations were performed by the Environmental Science Division of Argonne National Laboratory, on behalf of the CCC/USDA. The main activities for the site investigation were conducted in June 2012, and indoor and ambient air sampling was performed in February 2013. This report presents the findings of the investigations at Sylvan Grove.« less

Predicting carbon dioxide and energy fluxes across global FLUXNET sites with regression algorithms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tramontana, Gianluca; Jung, Martin; Schwalm, Christopher R.

Spatio-temporal fields of land–atmosphere fluxes derived from data-driven models can complement simulations by process-based land surface models. While a number of strategies for empirical models with eddy-covariance flux data have been applied, a systematic intercomparison of these methods has been missing so far. In this study, we performed a cross-validation experiment for predicting carbon dioxide, latent heat, sensible heat and net radiation fluxes across different ecosystem types with 11 machine learning (ML) methods from four different classes (kernel methods, neural networks, tree methods, and regression splines). We applied two complementary setups: (1) 8-day average fluxes based on remotely sensed data andmore » (2) daily mean fluxes based on meteorological data and a mean seasonal cycle of remotely sensed variables. The patterns of predictions from different ML and experimental setups were highly consistent. There were systematic differences in performance among the fluxes, with the following ascending order: net ecosystem exchange ( R 2 < 0.5), ecosystem respiration ( R 2 > 0.6), gross primary production ( R 2> 0.7), latent heat ( R 2 > 0.7), sensible heat ( R 2 > 0.7), and net radiation ( R 2 > 0.8). The ML methods predicted the across-site variability and the mean seasonal cycle of the observed fluxes very well ( R 2 > 0.7), while the 8-day deviations from the mean seasonal cycle were not well predicted ( R 2 < 0.5). Fluxes were better predicted at forested and temperate climate sites than at sites in extreme climates or less represented by training data (e.g., the tropics). Finally, the evaluated large ensemble of ML-based models will be the basis of new global flux products.« less

Occupational exposure to dioxins by thermal oxygen cutting, welding, and soldering of metals.

PubMed

Menzel, H M; Bolm-Audorff, U; Turcer, E; Bienfait, H G; Albracht, G; Walter, D; Emmel, C; Knecht, U; Päpke, O

1998-04-01

This paper focuses on one aspect of occupational dioxin exposure that is novel and unexpected. Exposures in excess of the German threshold limit value of 50 pg international toxicity equivalent (I-TEQ)/m3 are very frequent, unpredictable, and sometimes very high--up to 6612 pg I-TEQ/m3--during thermal oxygen cutting at scrap metal and demolition sites. The same procedure involving virgin steel in steel trade and mass production of steel objects gave no such evidence, even though no final conclusions can be drawn because of the low number of samples analyzed. Low dioxin exposures during inert gas electric arc welding confirm previous literature findings, whereas soldering and thermal oxygen cutting in the presence of polyvinyl chloride give rise to concern. The consequences of occupational dioxin exposure were studied by analysis of the dioxin-blood concentration, the body burden, of men performing thermal oxygen cutting at scrap metal reclamation and demolition sites, in steel trade and producing plants as well as for industrial welders and white-collar workers. The results concerning body burdens are in excellent agreement with the dioxin exposure as characterized by dioxin air concentration in the workplace. The significant positive correlation between duration and frequency of performing thermal oxygen cutting at metal reclamation and demolition sites expressed in job-years and dioxin body burden speaks for the occupational origin of the observed overload after long times. The results reported here lead to consequences for occupational health, which are discussed and require immediate attention.

Internet-Based Partner Services in US Sexually Transmitted Disease Prevention Programs: 2009-2013.

PubMed

Moody, Victoria; Hogben, Matthew; Kroeger, Karen; Johnson, James

2015-01-01

Social networking sites have become increasingly popular venues for meeting sex partners. Today, some sexually transmitted disease (STD) programs conduct Internet-based partner services (IPS). The purpose of the study was to explore how the Internet is being used by STD prevention programs to perform partner services. We assessed US STD prevention programs receiving funds through the 2008-2013 Comprehensive STD Prevention Systems cooperative agreement. We (1) reviewed 2009 IPS protocols in 57 funding applications against a benchmark of national guidelines and (2) surveyed persons who conducted IPS in jurisdictions conducting IPS in 2012. Of the 57 project areas receiving Comprehensive STD Prevention Systems funds, 74% provided an IPS protocol. States with IPS protocols had larger populations and more gonorrhea and syphilis cases (t = 2.2-2.6; all Ps < .05), although not higher rates of infection. Most protocols included staffing (92%) and IPS documentation (87%) requirements, but fewer had evaluation plans (29%) or social networking site engagement strategies (16%). Authority to perform a complete range of IPS activities (send e-mail, use social networking sites) was associated with contacting more partners via IPSs (P < .05). This study provides a snapshot of IPS activities in STD programs in the United States. Further research is needed to move from assessment to generating data that can assist training efforts and program action and, finally, to enable efficient IPS programs that are integrated into STD prevention and control efforts.

3D fully convolutional networks for subcortical segmentation in MRI: A large-scale study.

PubMed

Dolz, Jose; Desrosiers, Christian; Ben Ayed, Ismail

2018-04-15

This study investigates a 3D and fully convolutional neural network (CNN) for subcortical brain structure segmentation in MRI. 3D CNN architectures have been generally avoided due to their computational and memory requirements during inference. We address the problem via small kernels, allowing deeper architectures. We further model both local and global context by embedding intermediate-layer outputs in the final prediction, which encourages consistency between features extracted at different scales and embeds fine-grained information directly in the segmentation process. Our model is efficiently trained end-to-end on a graphics processing unit (GPU), in a single stage, exploiting the dense inference capabilities of fully CNNs. We performed comprehensive experiments over two publicly available datasets. First, we demonstrate a state-of-the-art performance on the ISBR dataset. Then, we report a large-scale multi-site evaluation over 1112 unregistered subject datasets acquired from 17 different sites (ABIDE dataset), with ages ranging from 7 to 64 years, showing that our method is robust to various acquisition protocols, demographics and clinical factors. Our method yielded segmentations that are highly consistent with a standard atlas-based approach, while running in a fraction of the time needed by atlas-based methods and avoiding registration/normalization steps. This makes it convenient for massive multi-site neuroanatomical imaging studies. To the best of our knowledge, our work is the first to study subcortical structure segmentation on such large-scale and heterogeneous data. Copyright © 2017 Elsevier Inc. All rights reserved.

Preliminary identification of potentially disruptive scenarios at the Greater Confinement Disposal Facility, Area 5 of the Nevada Test Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guzowski, R.V.; Newman, G.

1993-12-01

The Greater Confinement Disposal location is being evaluated to determine whether defense-generated transuranic waste buried at this location complies with the Containment Requirements established by the US Environmental Protection Agency. One step in determining compliance is to identify those combinations of events and processes (scenarios) that define possible future states of the disposal system for which performance assessments must be performed. An established scenario-development procedure was used to identify a comprehensive set of mutually exclusive scenarios. To assure completeness, 761 features, events, processes, and other listings (FEPS) were compiled from 11 references. This number was reduced to 205 primarily throughmore » the elimination of duplications. The 205 FEPs were screened based on site-specific, goal-specific, and regulatory criteria. Four events survived screening and were used in preliminary scenario development: (1) exploratory drilling penetrates a GCD borehole, (2) drilling of a withdrawal/injection well penetrates a GCD borehole, (3) subsidence occurs at the RWMS, and (4) irrigation occurs at the RWMS. A logic diagram was used to develop 16 scenarios from the four events. No screening of these scenarios was attempted at this time. Additional screening of the currently retained events and processes will be based on additional data and information from site-characterization activities. When screening of the events and processes is completed, a final set of scenarios will be developed and screened based on consequence and probability of occurrence.« less

A new maltose-inducible high-performance heterologous expression system in Bacillus subtilis.

PubMed

Yue, Jie; Fu, Gang; Zhang, Dawei; Wen, Jianping

2017-08-01

To improve heterologous proteins production, we constructed a maltose-inducible expression system in Bacillus subtilis. An expression system based on the promoter for maltose utilization constructed in B. subtilis. Successively, to improve the performance of the P malA -derived system, mutagenesis was employed by gradually shortening the length of P malA promoter and altering the spacing between the predicted MalR binding site and the -35 region. Furthermore, deletion of the maltose utilization genes (malL and yvdK) improved the P malA promoter activity. Finally, using this efficient maltose-inducible expression system, we enhanced the production of luciferase and D-aminoacylase, compared with the P hpaII system. A maltose-inducible expression system was constructed and evaluated. It could be used for high level expression of heterologous proteins production.

Sentinel-2: State of the Image Quality Calibration at the End of the Commissioning

NASA Astrophysics Data System (ADS)

Tremas, Thierry; Lonjou, Vincent; Lacherade, Sophie; Gaudel-Vacaresse, Angelique; Languille, Florie

2016-08-01

This article summarizes the activity of CNES during the In Orbit Calibration Phase of Sentinel 2A as well as the transfer of production of GIPP (Ground Image Processing Parameters) from CNES to ESRIN. The state of the main calibration parameters and performances, few months before PDGS is declared fully operational, are listed and explained.In radiometry a special attention is paid to the absolute calibration using the on-board diffuser, and the vicarious calibration methods using instrumented or statistically well characterized sites and inter- comparisons with other sensors. Regarding geometry, the presentation focuses on the performances of absolute location with and without reference points. The requirements of multi-band and multi-temporal registration are exposed. Finally, the construction and the rule of the GRI (Ground Reference Images) in the future are explained.

Estimating site occupancy rates for aquatic plants using spatial sub-sampling designs when detection probabilities are less than one

USGS Publications Warehouse

Nielson, Ryan M.; Gray, Brian R.; McDonald, Lyman L.; Heglund, Patricia J.

2011-01-01

Estimation of site occupancy rates when detection probabilities are <1 is well established in wildlife science. Data from multiple visits to a sample of sites are used to estimate detection probabilities and the proportion of sites occupied by focal species. In this article we describe how site occupancy methods can be applied to estimate occupancy rates of plants and other sessile organisms. We illustrate this approach and the pitfalls of ignoring incomplete detection using spatial data for 2 aquatic vascular plants collected under the Upper Mississippi River's Long Term Resource Monitoring Program (LTRMP). Site occupancy models considered include: a naïve model that ignores incomplete detection, a simple site occupancy model assuming a constant occupancy rate and a constant probability of detection across sites, several models that allow site occupancy rates and probabilities of detection to vary with habitat characteristics, and mixture models that allow for unexplained variation in detection probabilities. We used information theoretic methods to rank competing models and bootstrapping to evaluate the goodness-of-fit of the final models. Results of our analysis confirm that ignoring incomplete detection can result in biased estimates of occupancy rates. Estimates of site occupancy rates for 2 aquatic plant species were 19–36% higher compared to naive estimates that ignored probabilities of detection <1. Simulations indicate that final models have little bias when 50 or more sites are sampled, and little gains in precision could be expected for sample sizes >300. We recommend applying site occupancy methods for monitoring presence of aquatic species.

Selection of the Mars Science Laboratory landing site

USGS Publications Warehouse

Golombek, M.; Grant, J.; Kipp, D.; Vasavada, A.; Kirk, Randolph L.; Fergason, Robin L.; Bellutta, P.; Calef, F.; Larsen, K.; Katayama, Y.; Huertas, A.; Beyer, R.; Chen, A.; Parker, T.; Pollard, B.; Lee, S.; Hoover, R.; Sladek, H.; Grotzinger, J.; Welch, R.; Dobrea, E. Noe; Michalski, J.; Watkins, M.

2012-01-01

The selection of Gale crater as the Mars Science Laboratory landing site took over five years, involved broad participation of the science community via five open workshops, and narrowed an initial >50 sites (25 by 20 km) to four finalists (Eberswalde, Gale, Holden and Mawrth) based on science and safety. Engineering constraints important to the selection included: (1) latitude (±30°) for thermal management of the rover and instruments, (2) elevation (<-1 km) for sufficient atmosphere to slow the spacecraft, (3) relief of <100-130 m at baselines of 1-1000 m for control authority and sufficient fuel during powered descent, (4) slopes of <30° at baselines of 2-5 m for rover stability at touchdown, (5) moderate rock abundance to avoid impacting the belly pan during touchdown, and (6) a radar-reflective, load-bearing, and trafficable surface that is safe for landing and roving and not dominated by fine-grained dust. Science criteria important for the selection include the ability to assess past habitable environments, which include diversity, context, and biosignature (including organics) preservation. Sites were evaluated in detail using targeted data from instruments on all active orbiters, and especially Mars Reconnaissance Orbiter. All of the final four sites have layered sedimentary rocks with spectral evidence for phyllosilicates that clearly address the science objectives of the mission. Sophisticated entry, descent and landing simulations that include detailed information on all of the engineering constraints indicate all of the final four sites are safe for landing. Evaluation of the traversabilty of the landing sites and target “go to” areas outside of the ellipse using slope and material properties information indicates that all are trafficable and “go to” sites can be accessed within the lifetime of the mission. In the final selection, Gale crater was favored over Eberswalde based on its greater diversity and potential habitability.

75 FR 26166 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-11

... issuing a Notice of Intent to Delete the Asbestos Dump Superfund Site (Site) located in Meyersville, New... of today's Federal Register, we are publishing a direct final Notice of Deletion of the Asbestos Dump...

Final ecosystem goods and services enhance societal relevance of contaminated-site remediation

EPA Science Inventory

Background/Question/Methods Exposure to environmental stressors can adversely affect both human health and ecological receptors and impacts on the latter influence the community's overall vulnerability. Risk assessment guidance promotes conceptual site models to integrate multip...

76 FR 37143 - Buck Island, Green Cay, and Sandy Point National Wildlife Refuges, U.S. Virgin Islands; Final...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

... refuge Web site, distribute information, maintain signage on the island identifying it as a national... continue to maintain the refuge Web site, distribute information, maintain limited signage on the island...

Appreciating "Thirdspace": An Alternative Way of Viewing and Valuing Site-Specific Dance Performance

ERIC Educational Resources Information Center

Munjee, Tara

2014-01-01

Site-specific dance performance involves the presentation of choreography in connection with a site. The context of the site combined with a viewer's personal history, beliefs, and identity impact the reading and appreciation of the performance. Although both stage and site dance performance valuing elicit multiple interpretations of artistic…

A review on the benchmarking concept in Malaysian construction safety performance

NASA Astrophysics Data System (ADS)

Ishak, Nurfadzillah; Azizan, Muhammad Azizi

2018-02-01

Construction industry is one of the major industries that propels Malaysia's economy in highly contributes to our nation's GDP growth, yet the high fatality rates on construction sites have caused concern among safety practitioners and the stakeholders. Hence, there is a need of benchmarking in performance of Malaysia's construction industry especially in terms of safety. This concept can create a fertile ground for ideas, but only in a receptive environment, organization that share good practices and compare their safety performance against other benefit most to establish improvement in safety culture. This research was conducted to study the awareness important, evaluate current practice and improvement, and also identify the constraint in implement of benchmarking on safety performance in our industry. Additionally, interviews with construction professionals were come out with different views on this concept. Comparison has been done to show the different understanding of benchmarking approach and how safety performance can be benchmarked. But, it's viewed as one mission, which to evaluate objectives identified through benchmarking that will improve the organization's safety performance. Finally, the expected result from this research is to help Malaysia's construction industry implement best practice in safety performance management through the concept of benchmarking.

Remedial action plan and site design for stabilization of the inactive uranium mill tailings sites at Rifle, Colorado. Volume 5, Addenda D6--D8 to Appendix D: Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-02-01

This volume contains appendices D6 through D8 containing laboratory test data: from MK-F investigation, 1987, Old Rifle and New Rifle sites; on bentonite amended radon barrier material; and from MK-F investigation, 1987, riprap tests.

Superfund record of decision (EPA Region 10): Standard Steel and Metals Salvage Yard, (USDOT), Superfund Site, Anchorage, AK, July 16, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-08-01

The decision document presents the selected remedial action for the Standard Steel and Metals Salvage Yard, in Anchorage, Alaska. This is the final remedial action for the site. The site was not divided into operable units. The Removal Action utilized treatment as a principle element for the principle sources.

Future landfill emissions and the effect of final cover installation--a case study.

PubMed

Laner, David; Fellner, Johann; Brunner, Paul H

2011-07-01

Municipal solid waste (MSW) landfills are potential long-term sources of emissions. Hence, they need to be managed after closure until they do not pose a threat to humans or the environment. The case study on the Breitenau MSW landfill was performed to evaluate future emission levels for this site and to illustrate the effect of final cover installation with respect to long-term environmental risks. The methodology was based on a comprehensive assessment of the state of the landfill and included analysis of monitoring data, investigations of landfilled waste, and an evaluation of containment systems. A model to estimate future emission levels was established and site-specific predictions of leachate emissions were presented based on scenario analysis. The results are used to evaluate the future pollution potential of the landfill and to compare different aftercare concepts in view of long-term emissions. As some leachable substances became available for water flow during cover construction due to a change in the water flow pattern of the waste, a substantial increase in leachate concentrations could be observed at the site (e.g. concentrations of chloride increased from 200 to 800 mg/l and of ammonia-nitrogen from 140 to about 500 mg/l). A period of intensive flushing before the final cover installation could have reduced the amount of leachable substances within the landfill body and rapidly decreased the leachate concentrations to 11 mg Cl/l and 79 mg NH(4)-N/l within 50 years. Contrarily, the minimization of water infiltration is associated with leachate concentrations in a high range for centuries (above 400 mg Cl/l and 200 mg NH(4)-N/l) with low concomitant annual emission loads (below 12 kg/year of Cl or 9 kg/year of NH(4)-N, respectively). However, an expected gradual decrease of barrier efficiency over time would be associated with higher emission loads of 50 kg of chloride and 30 kg of ammonia-nitrogen at the maximum, but a faster decrease of leachate concentration levels. Copyright © 2011 Elsevier Ltd. All rights reserved.

Evaluation of Vitrification Processing Step for Rocky Flats Incinerator Ash

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wigent, W.L.; Luey, J.K.; Scheele, R.D.

In 1997, Pacific Northwest National Laboratory (PNNL) staff developed a processing option for incinerator ash at the Rocky Flats Environmental Technology Sites (RFETS). This work was performed with support from Los Alamos National Laboratory (LANL) and Safe Sites of Colorado (SSOC). A description of the remediation needs for the RFETS incinerator ash is provided in a report summarizing the recommended processing option for treatment of the ash (Lucy et al. 1998). The recommended process flowsheet involves a calcination pretreatment step to remove carbonaceous material followed by a vitrification processing step for a mixture of glass tit and calcined incinerator ash.more » Using the calcination pretreatment step to remove carbonaceous material reduced process upsets for the vitrification step, allowed for increased waste loading in the final product, and improved the quality of the final product. Figure 1.1 illustrates the flow sheet for the recommended processing option for treatment of RFETS incinerator ash. In 1998, work at PNNL further developed the recommended flow sheet through a series of studies to better define the vitrification operating parameters and to address secondary processing issues (such as characterizing the offgas species from the calcination process). Because a prototypical rotary calciner was not available for use, studies to evaluate the offgas from the calcination process were performed using a benchtop rotary calciner and laboratory-scale equipment (Lucy et al. 1998). This report focuses on the vitrification process step after ash has been calcined. Testing with full-scale containers was performed using ash surrogates and a muffle furnace similar to that planned for use at RFETS. Small-scale testing was performed using plutonium-bearing incinerator ash to verify performance of the waste form. Ash was not obtained from RFETS because of transportation requirements to calcine the incinerator ash prior to shipment of the material. Because part of PNNL's work was to characterize the ash prior to calcination and to investigate the effect of calcination on product quality, representative material was obtained from LANL. Ash obtained from LANL was selected based on its similarity to that currently stored at RFETS. The plutonium-bearing ashes obtained from LANL are likely from a RFETS incinerator, but the exact origin was not identified.« less

77 FR 20399 - Agency Information Collection Activities: Notice; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-04

... document finalizing proposed revisions to the Consolidated Financial Statements for Bank Holding Companies..., 2012 (77 FR 15755), a document finalizing proposed revisions to the Consolidated Financial Statements... financial information collection on BHCs between on-site inspections and contained two typographical errors...

Report: Lack of Final Guidance on Vapor Intrusion Impedes Efforts to Address Indoor Air Risks

EPA Pesticide Factsheets

Report #10-P-0042, December 14, 2009. EPA’s efforts to protect human health at sites where vapor intrusion risks may occur have been impeded by the lack of final Agency guidance on vapor intrusion risks.

Site descriptive modeling as a part of site characterization in Sweden - Concluding the surface based investigations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andersson, Johan; Winberg, Anders; Skagius, Kristina

The Swedish Nuclear Fuel and Waste Management Co., SKB, is currently finalizing its surface based site investigations for the final repository for spent nuclear fuel in the municipalities of Oestharmnar (the Forsmark area) and Oskarshamn (the Simpevar/Laxemar area). The investigation data are assessed into a Site Descriptive Model, constituting a synthesis of geology, rock mechanics, thermal properties, hydrogeology, hydro-geochemistry, transport properties and a surface system description. Site data constitute a wide range of different measurement results. These data both need to be checked for consistency and to be interpreted into a format more amenable for three-dimensional modeling. The three-dimensional modelingmore » (i.e. estimating the distribution of parameter values in space) is made in a sequence where the geometrical framework is taken from the geological models and in turn used by the rock mechanics, thermal and hydrogeological modeling. These disciplines in turn are partly interrelated, and also provide feedback to the geological modeling, especially if the geological description appears unreasonable when assessed together with the other data. Procedures for assessing the uncertainties and the confidence in the modeling have been developed during the course of the site modeling. These assessments also provide key input to the completion of the site investigation program. (authors)« less

EPA's National Dioxin Air Monitoring Network (NDAMN): Design, implementation, and final results

NASA Astrophysics Data System (ADS)

Lorber, Matthew; Ferrario, Joseph; Byrne, Christian

2013-10-01

The U.S. Environmental Protection Agency (U.S. EPA) established the National Dioxin Air Monitoring Network (NDAMN) in June of 1998, and operated it until November of 2004. The objective of NDAMN was to determine background air concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (dl-PCBs). NDAMN started with 10 sampling sites, adding more over time until the final count of 34 sites was reached by the beginning of 2003. Samples were taken quarterly, and the final sample count was 685. All samples were measured for 17 PCDD/PCDF congeners, 8 PCDD/PCDF homologue groups, and 7 dl-PCBs (note: 5 additional dl-PCBs were added for samples starting in the summer of 2002; 317 samples had measurements of 12 dl-PCBs). The overall average total toxic equivalent (TEQ) concentration in the United States was 11.2 fg TEQ m-3 with dl-PCBs contributing 0.8 fg TEQ m-3 (7%) to this total. The archetype dioxin and furan background air congener profile was seen in the survey averages and in most individual samples. This archetype profile is characterized by low and similar concentrations for tetra - through hexa PCDD/PCDF congeners, with elevations in four congeners - a hepta dioxin and furan congener, and both octa congeners. Sites were generally categorized as urban (4 sites), rural (23 sites), or remote (7 sites). The average TEQ concentrations over all sites and samples within these categories were: urban = 15.9 fg TEQ m-3, rural = 13.9 fg TEQ m-3, and remote = 1.2 fg TEQ m-3. Rural sites showed elevations during the fall or winter months when compared to the spring or summer months, and the same might be said for urban sites, but the remote sites appear to show little variation over time. The four highest individual moment measurements were 847, 292, 241, and 132 fg TEQ m-3. For the 847 and 292 fg TEQ m-3 samples, the concentrations of all congeners were elevated over their site averages, but for the 241 and 132 fg TEQ m-3 measurements, only the PCDD congeners were elevated while PCDF and dl-PCB concentrations were similar to the site averages.

Final Hazard Categorization for the Remediation of Six 300-FF-2 Operable Unit Solid Waste Burial Grounds

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. D. Ludowise

2006-12-12

This report provides the final hazard categorization (FHC) for the remediation of six solid waste disposal sites (referred to as burial grounds) located in the 300-FF-2 Operable Unit (OU) on the Hanford Site. These six sites (618-1, 618-2, 618-3, 618-7, 618-8, and 618-13 Burial Grounds) were determined to have a total radionuclide inventory (WCH 2005a, WCH 2005d, WCH 2005e and WCH 2006b) that exceeds the DOE-STD-1027 Category 3 threshold quantity (DOE 1997) and are the subject of this analysis. This FHC document examines the hazards, identifies appropriate controls to manage the hazards, and documents the FHC and commitments for themore » 300-FF-2 Burial Grounds Remediation Project.« less

Quantum dynamics of water dissociative chemisorption on rigid Ni(111): An approximate nine-dimensional treatment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang, Bin, E-mail: bjiangch@ustc.edu.cn, E-mail: hguo@unm.edu; Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, New Mexico 87131; Song, Hongwei

The quantum dynamics of water dissociative chemisorption on the rigid Ni(111) surface is investigated using a recently developed nine-dimensional potential energy surface. The quantum dynamical model includes explicitly seven degrees of freedom of D{sub 2}O at fixed surface sites, and the final results were obtained with a site-averaging model. The mode specificity in the site-specific results is reported and analyzed. Finally, the approximate sticking probabilities for various vibrationally excited states of D{sub 2}O are obtained considering surface lattice effects and formally all nine degrees of freedom. The comparison with experiment reveals the inaccuracy of the density functional theory and suggestsmore » the need to improve the potential energy surface.« less

Downgrade of the Savannah River Sites FB-Line

DOE Office of Scientific and Technical Information (OSTI.GOV)

SADOWSKI, ED; YOURCHAK, RANDY; PRETZELLO MARJI

2005-07-05

This paper will discuss the Safeguards & Security (S&S) activities that resulted in the downgrade of the Savannah River Site's FB-Line (FBL) from a Category I Material Balance Area (MBA) in a Material Access Area (MAA) to a Category IV MBA in a Property Protection Area (PPA). The Safeguards activities included measurement of final product items, transferal of nuclear material to other Savannah River Site (SRS) facilities, discard of excess nuclear material items, and final measurements of holdup material. The Security activities included relocation and destruction of classified documents and repositories, decertification of a classified computer, access control changes, updatesmore » to planning documents, deactivation and removal of security systems, Human Reliability Program (HRP) removals, and information security training for personnel that will remain in the FBL PPA.« less

Measurement of attitudes toward commercial development of geothermal energy in Federal Region IX. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1981-06-01

A survey was conducted of ten target study groups and subgroups for Klamath Falls, Oregon, and Susanville, California: local government, current and potential industry at the site, relocators to the site, current and potential financial community, regulators, and current and potential promoters and developers. The results of benchmark attitudinal measurement is presented separately for each target group. A literature review was conducted and Macro-environmental attitudes of a sample of local government and industry personnel at the sites were assessed. An assessment of capabilities was made which involved two measurements. The first was a measurement of a sample of promoters, developers,more » and industrial service companies active at the site to determine infrastructure capabilities required by industry for geothermal plants. The second measurement involved analyzing a sample of industry management in the area and defining their requirements for plant retrofit and expansion. Finally, the processes used by the study group to analyze information to reach commitment and regulatory decisions that significantly impact on geothermal energy projects at the site were identified and defined.« less

Synthesis of Zn-MOF incorporating titanium-hydrides as active sites binding H{sub 2} molecules

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Jongsik, E-mail: jkim40@nd.edu; Ok Kim, Dong; Wook Kim, Dong

2015-10-15

This paper describes the synthetic effort for a Zn-MOF imparting Ti-H as a preferential binding site potentially capturing H{sub 2} molecules via Kubas-type interaction. The formation mechanism of Ti-H innate to the final material was potentially demonstrated to follow a radical dissociation rather than a β-hydrogen elimination and a C-H reductive elimination. - Graphical abstract: This study details the synthesis and the formation mechanism of Zn-MOF adsorbent site-isolating TiH{sub 3} that can potentially capture H{sub 2} molecules via Kubas-binding mechanism. - Highlights: • OH-functionalized Zn-MOF was employed as a reactive template to site-isolate TiH{sub 3}. • This MOF was post-syntheticallymore » modified using a tetracyclohexyl titanium (IV). • This intermediate was hydrogenolyzed to change ligand from cyclohexyl to hydride. • Formation mechanism of TiH{sub 3} was investigated via two control GC–MS experiments. • Final Zn-MOF potentially site-isolating TiH{sub 3} species was used as a H{sub 2} adsorbent.« less

Superfund Record of Decision (EPA Region 4): Newsom Brothers/Old Reichhold, Columbia, MS. (First remedial action), September 1989. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1989-09-18

The 81-acre Newsom Brothers/Old Reichhold site is in Marion County, Columbia, Mississippi. Site activities included producing tall oils, turpentine, calcium and zinc resinates, and polymerized and rubber resins. Furthermore, PCP was apparently mixed with diesel oil and sold, and xylenes were used in a number of processes. A State investigation in 1976 revealed that waste water containing phenols, oil, and grease was discharging to a small creek. Further investigations resulted in EPA performing an immediate removal action in 1984, which included the removal of over 600 surface drums from the site and excavating and draining two ponds, one of whichmore » was subsequently filled with clean fill. Onsite buried drum areas were the target of another EPA removal action conducted in 1987-88. In addition there is an extensive system of concrete drains that served to collect and drain spilled wastes and rain water that has an area of runoff of approximately 300,000 square feet. The primary contaminants of concern in the soil, sediment, and bulked wastes are organics including PAHs, PCBs, and PCP, and metals.« less

3-ω damage threshold evaluation of final optics components using Beamlet Mule and off-line testing

NASA Astrophysics Data System (ADS)

Kozlowski, Mark R.; Maricle, Stephen M.; Mouser, Ron P.; Schwartz, Sheldon; Wegner, Paul J.; Weiland, Timothy L.

1999-07-01

A statistics-based model is being develop to predict the laser-damage-limited lifetime of UV optical components on the NIF laser. In order to provide data for the mode, laser damage experiments were performed on the Beamlet laser system at LLNL. An early protoype NIF focus lens was exposed to twenty 351 nm pulses at an average fluence of 5 J/cm2, 3ns. Using a high resolution optic inspection inspection system a total of 353 damage sites was detected within the 1160 cm2 beam aperture. Through inspections of the lens before, after and, in some cases, during the campaign, pulse to pulse damage growth rates were measured for damage initiating both on the surface and at bulk inclusions. Growth rates as high as 79 micrometers /pulse were observed for damage initiating at pre-existing scratches in the surface. For most damage sites on the optic, both on the surface and at bulk inclusions. Growth rates as high as 79 micrometers /pulse were observed for damage initiating at per- existing scratches in the surface. For most damage sites on the optic, both surface and bulk, the damage growth rate was approximately 10(Mu) m/pulse.

Regulatory controls on the hydrogeological characterization of a mixed waste disposal site, Radioactive Waste Management Complex, Idaho National Engineering Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ruebelmann, K.L.

1990-01-01

Following the detection of chlorinated volatile organic compounds in the groundwater beneath the SDA in the summer of 1987, hydrogeological characterization of the Radioactive Waste Management Complex (RWMC), Idaho National Engineering Laboratory (INEL) was required by the Resource Conservation and Recovery Act (RCRA). The waste site, the Subsurface Disposal Area (SDA), is the subject of a RCRA Corrective Action Program. Regulatory requirements for the Corrective Action Program dictate a phased approach to evaluation of the SDA. In the first phase of the program, the SDA is the subject of a RCRA Facility Investigation (RIF), which will obtain information to fullymore » characterize the physical properties of the site, determine the nature and extent of contamination, and identify pathways for migration of contaminants. If the need for corrective measures is identified during the RIF, a Corrective Measures Study (CMS) will be performed as second phase. Information generated during the RIF will be used to aid in the selection and implementation of appropriate corrective measures to correct the release. Following the CMS, the final phase is the implementation of the selected corrective measures. 4 refs., 1 fig.« less

Using trace element content and lead isotopic composition to assess sources of PM in Tijuana, Mexico

NASA Astrophysics Data System (ADS)

Salcedo, D.; Castro, T.; Bernal, J. P.; Almanza-Veloz, V.; Zavala, M.; González-Castillo, E.; Saavedra, M. I.; Perez-Arvízu, O.; Díaz-Trujillo, G. C.; Molina, L. T.

2016-05-01

PM2.5 samples were collected at two urban sites (Parque Morelos (PQM) and CECyTE (CEC)) in Tijuana during the Cal-Mex campaign from May 24 to June 5, 2010. Concentration of trace elements (Mg, Al, Ti, V, Mn, Fe, Co, Ni, Zn, Cu, Ga, As, Se, Rb, Sr, Mo, Cd, Sn, Sb, Ba, La, Ce, and Pb), and Pb isotopic composition were determined in order to study the sources of PM impacting each site. Other chemical analysis (gravimetric, elemental and organic carbon (EC/OC), and polycyclic aromatic hydrocarbons (PAHs)), were also performed. Finally, back-trajectories were calculated to facilitate the interpretation of the chemical data. Trace elements results show that CEC is a receptor site affected by mixed regional sources: sea salt, mineral, urban, and industrial. On the other hand, PQM seems to be impacted mainly by local sources. In particular, Pb at CEC is of anthropogenic, as well as crustal origin. This conclusion is supported by the lead isotopic composition, whose values are consistent with a combination of lead extracted from US mines, and lead from bedrocks in the Mexican Sierras. Some of the time variability observed can be explained using the back-trajectories.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Namhata, Argha; Oladyshkin, Sergey; Dilmore, Rober

Carbon dioxide (CO2) storage into geological formations is regarded as an important mitigation strategy for anthropogenic CO2 emissions to the atmosphere. This study first simulates the leakage of CO2 and brine from a storage reservoir through the caprock. Then, we estimate the resulting pressure changes at the zone overlying the caprock also known as Above Zone Monitoring Interval (AZMI). A data-driven approach of arbitrary Polynomial Chaos (aPC) Expansion is then used to quantify the uncertainty in the above zone pressure prediction based on the uncertainties in different geologic parameters. Finally, a global sensitivity analysis is performed with Sobol indices basedmore » on the aPC technique to determine the relative importance of different parameters on pressure prediction. The results indicate that there can be uncertainty in pressure prediction locally around the leakage zones. The degree of such uncertainty in prediction depends on the quality of site specific information available for analysis. The scientific results from this study provide substantial insight that there is a need for site-specific data for efficient predictions of risks associated with storage activities. The presented approach can provide a basis of optimized pressure based monitoring network design at carbon storage sites.« less

Linde FUSRAP Site Remediation: Engineering Challenges and Solutions of Remedial Activities on an Active Industrial Facility - 13506

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beres, Christopher M.; Fort, E. Joseph; Boyle, James D.

2013-07-01

The Linde FUSRAP Site (Linde) is located in Tonawanda, New York at a major research and development facility for Praxair, Inc. (Praxair). Successful remediation activities at Linde combines meeting cleanup objectives of radiological contamination while minimizing impacts to Praxair business operations. The unique use of Praxair's property coupled with an array of active and abandoned utilities poses many engineering and operational challenges; each of which has been overcome during the remedial action at Linde. The U.S. Army Corps of Engineers - Buffalo District (USACE) and CABRERA SERVICES, INC. (CABRERA) have successfully faced engineering challenges such as relocation of an abovegroundmore » structure, structural protection of an active water line, and installation of active mechanical, electrical, and communication utilities to perform remediation. As remediation nears completion, continued success of engineering challenges is critical as remaining activities exist in the vicinity of infrastructure essential to business operations; an electrical substation and duct bank providing power throughout the Praxair facility. Emphasis on engineering and operations through final remediation and into site restoration will allow for the safe and successful completion of the project. (authors)« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Savy, J.

New design and evaluation guidelines for department of energy facilities subjected to natural phenomena hazard, are being finalized. Although still in draft form at this time, the document describing those guidelines should be considered to be an update of previously available guidelines. The recommendations in the guidelines document mentioned above, and simply referred to as the guidelines'' thereafter, are based on the best information at the time of its development. In particular, the seismic hazard model for the Princeton site was based on a study performed in 1981 for Lawrence Livermore National Laboratory (LLNL), which relied heavily on the resultsmore » of the NRC's Systematic Evaluation Program and was based on a methodology and data sets developed in 1977 and 1978. Considerable advances have been made in the last ten years in the domain of seismic hazard modeling. Thus, it is recommended to update the estimate of the seismic hazard at the DOE sites whenever possible. The major differences between previous estimates and the ones proposed in this study for the PPPL are in the modeling of the strong ground motion at the site, and the treatment of the total uncertainty in the estimates to include knowledge uncertainty, random uncertainty, and expert opinion diversity as well. 28 refs.« less

Real-time correction of tsunami site effect by frequency-dependent tsunami-amplification factor

NASA Astrophysics Data System (ADS)

Tsushima, H.

2017-12-01

For tsunami early warning, I developed frequency-dependent tsunami-amplification factor and used it to design a recursive digital filter that can be applicable for real-time correction of tsunami site response. In this study, I assumed that a tsunami waveform at an observing point could be modeled by convolution of source, path and site effects in time domain. Under this assumption, spectral ratio between offshore and the nearby coast can be regarded as site response (i.e. frequency-dependent amplification factor). If the amplification factor can be prepared before tsunamigenic earthquakes, its temporal convolution to offshore tsunami waveform provides tsunami prediction at coast in real time. In this study, tsunami waveforms calculated by tsunami numerical simulations were used to develop frequency-dependent tsunami-amplification factor. Firstly, I performed numerical tsunami simulations based on nonlinear shallow-water theory from many tsuanmigenic earthquake scenarios by varying the seismic magnitudes and locations. The resultant tsunami waveforms at offshore and the nearby coastal observing points were then used in spectral-ratio analysis. An average of the resulted spectral ratios from the tsunamigenic-earthquake scenarios is regarded as frequency-dependent amplification factor. Finally, the estimated amplification factor is used in design of a recursive digital filter that can be applicable in time domain. The above procedure is applied to Miyako bay at the Pacific coast of northeastern Japan. The averaged tsunami-height spectral ratio (i.e. amplification factor) between the location at the center of the bay and the outside show a peak at wave-period of 20 min. A recursive digital filter based on the estimated amplification factor shows good performance in real-time correction of tsunami-height amplification due to the site effect. This study is supported by Japan Society for the Promotion of Science (JSPS) KAKENHI grant 15K16309.

Influence of Green Tides in Coastal Nursery Grounds on the Habitat Selection and Individual Performance of Juvenile Fish

PubMed Central

Murillo, Laurence; Randon, Marine; Lebot, Clément

2017-01-01

Coastal ecosystems, which provide numerous essential ecological functions for fish, are threatened by the proliferation of green macroalgae that significantly modify habitat conditions in intertidal areas. Understanding the influence of green tides on the nursery function of these ecosystems is essential to determine their potential effects on fish recruitment success. In this study, the influence of green tides on juvenile fish was examined in an intertidal sandy beach area, the Bay of Saint-Brieuc (Northwestern France), during two annual cycles of green tides with varying levels of intensity. The responses of three nursery-dependent fish species, the pelagic Sprattus sprattus (L.), the demersal Dicentrarchus labrax (L.) and the benthic Pleuronectes platessa L., were analysed to determine the effects of green tides according to species-specific habitat niche and behaviour. The responses to this perturbation were investigated based on habitat selection and a comparison of individual performance between a control and an impacted site. Several indices on different integrative scales were examined to evaluate these responses (antioxidant defence capacity, muscle total lipid, morphometric condition and growth). Based on these analyses, green tides affect juvenile fish differently according to macroalgal density and species-specific tolerance, which is linked to their capacity to move and to their distribution in the water column. A decreasing gradient of sensitivity was observed from benthic to demersal and pelagic fish species. At low densities of green macroalgae, the three species stayed at the impacted site and the growth of plaice was reduced. At medium macroalgal densities, plaice disappeared from the impacted site and the growth of sea bass and the muscle total lipid content of sprat were reduced. Finally, when high macroalgal densities were reached, none of the studied species were captured at the impacted site. Hence, sites affected by green tides are less favourable nursery grounds for all the studied species, with species-specific effects related to macroalgal density. PMID:28125605

Influence of Green Tides in Coastal Nursery Grounds on the Habitat Selection and Individual Performance of Juvenile Fish.

PubMed

Le Luherne, Emilie; Le Pape, Olivier; Murillo, Laurence; Randon, Marine; Lebot, Clément; Réveillac, Elodie

2017-01-01

Coastal ecosystems, which provide numerous essential ecological functions for fish, are threatened by the proliferation of green macroalgae that significantly modify habitat conditions in intertidal areas. Understanding the influence of green tides on the nursery function of these ecosystems is essential to determine their potential effects on fish recruitment success. In this study, the influence of green tides on juvenile fish was examined in an intertidal sandy beach area, the Bay of Saint-Brieuc (Northwestern France), during two annual cycles of green tides with varying levels of intensity. The responses of three nursery-dependent fish species, the pelagic Sprattus sprattus (L.), the demersal Dicentrarchus labrax (L.) and the benthic Pleuronectes platessa L., were analysed to determine the effects of green tides according to species-specific habitat niche and behaviour. The responses to this perturbation were investigated based on habitat selection and a comparison of individual performance between a control and an impacted site. Several indices on different integrative scales were examined to evaluate these responses (antioxidant defence capacity, muscle total lipid, morphometric condition and growth). Based on these analyses, green tides affect juvenile fish differently according to macroalgal density and species-specific tolerance, which is linked to their capacity to move and to their distribution in the water column. A decreasing gradient of sensitivity was observed from benthic to demersal and pelagic fish species. At low densities of green macroalgae, the three species stayed at the impacted site and the growth of plaice was reduced. At medium macroalgal densities, plaice disappeared from the impacted site and the growth of sea bass and the muscle total lipid content of sprat were reduced. Finally, when high macroalgal densities were reached, none of the studied species were captured at the impacted site. Hence, sites affected by green tides are less favourable nursery grounds for all the studied species, with species-specific effects related to macroalgal density.

Closure Report for CAU No. 430: Buried Depleted Uraniuim Artillery Round No. 1, Tonopah Test Range, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1997-02-25

1.1 Purpose This Closure Report presents the information obtained from investigative actions performed to justify the decision for clean closure of CAU 430 through "No Further Action." The investigative actions were performed per the Streamlined Approach for Environmental Restoration Plan, CA UNO. 430: Buried Depleted Uranium Artille~ Round No. 1, Tonopah Test Range (DOE/NV, 1996a) (hereafter referred to as the SAFER Plan). The Buried DU Artillery Round No. 1 is located approximately 1.1 kilometers (km) (0.7 mile [mi]) south of Avenue 13 in the test area south of Area 9 (Figure 1-2). The site was thought to consist of amore » potentially unexploded W-79 Joint Test Assembly (JTA) test artillery projectile with high explosives (HE) and DU. The DU was substituted for Special Nuclear Material to prevent a nuclear explosion and yet retain the physical characteristics of uranium for ballistic and other mechanical tests. The projectile was reportedly buried in one pit, approximately 5 to 10 feet (ft) deep (Smith, 1993; Smith, 1996; Quas, 1996). The exact location of the burial pit is unknown; however, three disturbed areas (Sites A, B, and C) were identified through geophysical surveys, site visits, and employee interviews as possible locations of the test projectile (Figure 1-3). Results of the investigation are summarized within this Closure Report. Additional information about the site and investigation activities may be found in the SAFER Plan (DOE/NV, 1996a). 1.2 Scope The objectives of the SAFER Plan (DOE/NV, 1996a) activities were to prepare the site for closure through locating and identi~ing the projectile (Buried DU Artillery Round No. 1), destroying the projectile and any remaining components, collecting soil samples to detect residual contamination resulting from projectile destruction, and finally, remediating residual contamination.« less

Experience in Grid Site Testing for ATLAS, CMS and LHCb with HammerCloud

NASA Astrophysics Data System (ADS)

Elmsheuser, Johannes; Medrano Llamas, Ramón; Legger, Federica; Sciabà, Andrea; Sciacca, Gianfranco; Úbeda García, Mario; van der Ster, Daniel

2012-12-01

Frequent validation and stress testing of the network, storage and CPU resources of a grid site is essential to achieve high performance and reliability. HammerCloud was previously introduced with the goals of enabling VO- and site-administrators to run such tests in an automated or on-demand manner. The ATLAS, CMS and LHCb experiments have all developed VO plugins for the service and have successfully integrated it into their grid operations infrastructures. This work will present the experience in running HammerCloud at full scale for more than 3 years and present solutions to the scalability issues faced by the service. First, we will show the particular challenges faced when integrating with CMS and LHCb offline computing, including customized dashboards to show site validation reports for the VOs and a new API to tightly integrate with the LHCbDIRAC Resource Status System. Next, a study of the automatic site exclusion component used by ATLAS will be presented along with results for tuning the exclusion policies. A study of the historical test results for ATLAS, CMS and LHCb will be presented, including comparisons between the experiments’ grid availabilities and a search for site-based or temporal failure correlations. Finally, we will look to future plans that will allow users to gain new insights into the test results; these include developments to allow increased testing concurrency, increased scale in the number of metrics recorded per test job (up to hundreds), and increased scale in the historical job information (up to many millions of jobs per VO).

Immediate provisionalization of immediate implants in the esthetic zone: a prospective case series evaluating implant survival, esthetics, and bone maintenance.

PubMed

Levin, Barry P; Wilk, Brian L

2013-05-01

This prospective study evaluates immediately placed and immediately provisionalized implants in the esthetic zone. All implants were TiO2-blasted, fluoride-modified, grade 4 titanium, with a coronal microthread design. Bone grafting and guided bone regeneration (GBR) was performed at all sites, and screw-retained temporary restorations were delivered on the day of surgery. All of the provisional crown(s) were out of occlusal function and remained in place for at least 8 weeks prior to initiation of definitive restorative therapy. Bone maintenance (BM) was considered successful if radiographs demonstrated proximal bone levels even or coronal to the implant platform. Of the 29 implants placed, 25 (86 percent) achieved bone maintenance at least 12 months post-loading with the final restorations. This study was considered successful, with 100 percent implant survival after at least 1 year loading of the final restoration, and 100 percent of patients were satisfied with the esthetics of their implant treatment.

Electrical engineering support of telemetered traffic monitoring sites : final report, March 2009.

DOT National Transportation Integrated Search

2009-03-01

"The aim of this project was to provide electrical engineering support for the telemetered traffic monitoring sites (TTMS) operated by the Statistics Office of the Florida Department of Transportation. This project was a companion to project BD-543-1...

KSC-82PC-0331

NASA Image and Video Library

1982-03-22

The Complex 39 press site buzzes with activity during the final countdown to the launch of the third space shuttle flight. More than 2,000 news media representatives from around the world crowded onto the press site this morning to watch the successful 11 a.m. launch.

Final Report: Independent Design Review, Celanese Fiber Operations Superfund Site, Shelby, North Carolina, EPA Region 4

EPA Pesticide Factsheets

The Celanese site is located in Shelby, North Carolina. Operation of the P&T system was discontinued on a trial basis for two years to evaluate monitored natural attenuation as a potential ground water remedy.

Environmental Assessment: Proposed U.S. Air Force Military Family Housing Privatization Initiative Patrick Air Force Base, Florida

DTIC Science & Technology

2008-11-03

Australian pine Cormorants resting on pilings in Banana River ( near North Housing Area ). FINAL Environmental Assessment for Proposed Privatization...the North and Central Housing areas are privatized. FINAL Environmental Assessment for Proposed Privatization of Military Housing PAFB... areas , although numerous groundwater wells are located immediately adjacent to both sites (Figure 3-1). FINAL Environmental Assessment for Proposed

Heat pump centered integrated community energy systems: system development. Georgia Institute of Technology final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wade, D.W.; Trammell, B.C.; Dixit, B.S.

1979-12-01

Heat Pump Centered-Integrated Community Energy Systems (HP-ICES) show the promise of utilizing low-grade thermal energy for low-quality energy requirements such as space heating and cooling. The Heat Pump - Wastewater Heat Recovery (HP-WHR) scheme is one approach to an HP-ICES that proposes to reclaim low-grade thermal energy from a community's wastewater effluent. This report develops the concept of an HP-WHR system, evaluates the potential performance and economics of such a system, and examines the potential for application. A thermodynamic performance analysis of a hypothetical system projects an overall system Coefficient of Performance (C.O.P.) of from 2.181 to 2.264 for waste-watermore » temperatures varying from 50/sup 0/F to 80/sup 0/F. Primary energy source savings from the nationwide implementation of this system is projected to be 6.0 QUADS-fuel oil, or 8.5 QUADS - natural gas, or 29.7 QUADS - coal for the period 1980 to 2000, depending upon the type and mix of conventional space conditioning systems which could be displaced with the HP-WHR system. Site-specific HP-WHR system designs are presented for two application communities in Georgia. Performance analyses for these systems project annual cycle system C.O.P.'s of 2.049 and 2.519. Economic analysis on the basis of a life cycle cost comparison shows one site-specific system design to be cost competitive in the immediate market with conventional residential and light commercial HVAC systems. The second site-specific system design is shown through a similar economic analysis to be more costly than conventional systems due mainly to the current low energy costs for natural gas. It is anticipated that, as energy costs escalate, this HP-WHR system will also approach the threshold of economic viability.« less

GSHSite: Exploiting an Iteratively Statistical Method to Identify S-Glutathionylation Sites with Substrate Specificity

PubMed Central

Chen, Yi-Ju; Lu, Cheng-Tsung; Huang, Kai-Yao; Wu, Hsin-Yi; Chen, Yu-Ju; Lee, Tzong-Yi

2015-01-01

S-glutathionylation, the covalent attachment of a glutathione (GSH) to the sulfur atom of cysteine, is a selective and reversible protein post-translational modification (PTM) that regulates protein activity, localization, and stability. Despite its implication in the regulation of protein functions and cell signaling, the substrate specificity of cysteine S-glutathionylation remains unknown. Based on a total of 1783 experimentally identified S-glutathionylation sites from mouse macrophages, this work presents an informatics investigation on S-glutathionylation sites including structural factors such as the flanking amino acids composition and the accessible surface area (ASA). TwoSampleLogo presents that positively charged amino acids flanking the S-glutathionylated cysteine may influence the formation of S-glutathionylation in closed three-dimensional environment. A statistical method is further applied to iteratively detect the conserved substrate motifs with statistical significance. Support vector machine (SVM) is then applied to generate predictive model considering the substrate motifs. According to five-fold cross-validation, the SVMs trained with substrate motifs could achieve an enhanced sensitivity, specificity, and accuracy, and provides a promising performance in an independent test set. The effectiveness of the proposed method is demonstrated by the correct identification of previously reported S-glutathionylation sites of mouse thioredoxin (TXN) and human protein tyrosine phosphatase 1b (PTP1B). Finally, the constructed models are adopted to implement an effective web-based tool, named GSHSite (http://csb.cse.yzu.edu.tw/GSHSite/), for identifying uncharacterized GSH substrate sites on the protein sequences. PMID:25849935

Do metallic ports in tissue expanders affect postmastectomy radiation delivery?

PubMed

Damast, Shari; Beal, Kathryn; Ballangrud, Ase; Losasso, Thomas J; Cordeiro, Peter G; Disa, Joseph J; Hong, Linda; McCormick, Beryl L

2006-09-01

Postmastectomy radiation therapy (PMRT) is often delivered to patients with permanent breast implants. On occasion, patients are irradiated with a tissue expander (TE) in place before their permanent implant exchange. Because of concern of potential under-dosing in these patients, we examined the dosimetric effects of the Magna-Site (Santa Barbara, CA) metallic port that is present in certain TEs. We performed ex vivo film dosimetry with single 6-MV and 15-MV photon beams on a water phantom containing a Magna-Site disc in two orientations. Additionally, using in vivo films, we measured the exit dose from 1 patient's TE-reconstructed breast during chest wall treatment with 15-MV tangent beams. Finally, we placed thermoluminescent dosimeters (TLDs) on 6 patients with TEs who received PMRT delivered with 15-MV tangent beams. Phantom film dosimetry revealed decreased transmission in the region of the Magna-Site, particularly with the magnet in the parallel orientation (at 22 mm: 78% transmission with 6 MV, 84% transmission with 15 MV). The transmission measured by in vivo films during single beam treatment concurred with ex vivo results. TLD data showed acceptable variation in median dose to the skin (86-101% prescription dose). Because of potential dosimetric effects of the Magna-Site, it is preferable to treat PMRT patients with permanent implants. However, it is not unreasonable to treat with a TE because the volume of tissue affected by attenuation from the Magna-Site is small. In this scenario, we recommend using 15 MV photons with compensating bolus.

Remedial action plan and site design for stabilization of the inactive uranium mill tailings sites at Rifle, Colorado

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-02-01

This appendix assesses the present conditions and data gathered about the two inactive uranium mill tailings sites near Rifle, Colorado, and the designated disposal site six miles north of Rifle in the area of Estes Gulch. It consolidates available engineering, radiological, geotechnical, hydrological, meteorological, and other information pertinent to the design of the Remedial Action Plan (RAP). The data characterize conditions at the mill, tailings, and disposal site so that the Remedial Action Contractor (RAC) may complete final designs for the remedial actions.

Superfund record of decision (EPA Region 3): Stanley Kessler Superfund Site, King of Prussia, PA, September 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-09-29

This decision document presents the final selected remedial action for the Stanley Kessler Superfund Site (the Site). The selected remedy for the Site will restore contaminated ground water to its beneficial use by cleaning up the ground water to background levels as established by EPA or the appropriate Maximum Contaminant Levels or non-zero Maximum Contaminant Level Goals established under the Federal Safe Drinking Water Act whichever is more stringent. The selected remedy is the only planned action for the Site.

Environmental Assessment and Final Finding of No Significant Impact for Lantirn Village & Camera I Site Upgrades Fort Wainwright Yukon Training Area Fort Wainwright, Alaska

DTIC Science & Technology

2009-08-01

improved road access and overhead power. The site contains a WISS shelter, five (5) 40’ connex containers, UMTE pedestal, shelter, and a weather ...monitoring station (Figure 3- 1 ). 3.1.8.3 Camera I site consists of a roughly l acre site with semi-improved road access and overhead power. The site...characteristics such as microclimate , soil temperature, and moisture regimes. which in turn influence the type of vegetation that will be found there

Best Practices for Continuous Monitoring of Temperature and Flow in Wadeable Streams (Final Report)

EPA Science Inventory

This final report is a technical "best practices" document describing sensor deployment for and collection of continuous temperature and flow data at ungaged sites in wadeable streams. This document addresses questions related to equipment needs; configuration, placement, and ins...

Letter from Galo Jackson Final Comments on November 2012 Draft ofthe Remedial Investigation Report fpr Operable Unit 3-Upland Soils

EPA Pesticide Factsheets

Letter from Galo Jackson contains the Final Comments on November 2012 Draft ofthe Remedial Investigation Report for Operable Unit 3-Upland Soils: LCP Chemical National Priorities List Site, Brunswick, Glynn County, GA.

Effect of the size-selective silver clusters on lithium peroxide morphology in lithium–oxygen batteries

DOE PAGES

Lu, Jun; Cheng, Lei; Lau, Kah Chun; ...

2014-09-12

Lithium–oxygen batteries have the potential needed for long-range electric vehicles, but the charge and discharge chemistries are complex and not well understood. The active sites on cathode surfaces and their role in electrochemical reactions in aprotic lithium–oxygen cells are difficult to ascertain because the exact nature of the sites is unknown. In this paper, we report the deposition of subnanometre silver clusters of exact size and number of atoms on passivated carbon to study the discharge process in lithium–oxygen cells. The results reveal dramatically different morphologies of the electrochemically grown lithium peroxide dependent on the size of the clusters. Thismore » dependence is found to be due to the influence of the cluster size on the formation mechanism, which also affects the charge process. Finally, the results of this study suggest that precise control of subnanometre surface structure on cathodes can be used as a means to improve the performance of lithium–oxygen cells.« less

Multiple functions of the crustacean gill: osmotic/ionic regulation, acid-base balance, ammonia excretion, and bioaccumulation of toxic metals

PubMed Central

Henry, Raymond P.; Lucu, Čedomil; Onken, Horst; Weihrauch, Dirk

2012-01-01

The crustacean gill is a multi-functional organ, and it is the site of a number of physiological processes, including ion transport, which is the basis for hemolymph osmoregulation; acid-base balance; and ammonia excretion. The gill is also the site by which many toxic metals are taken up by aquatic crustaceans, and thus it plays an important role in the toxicology of these species. This review provides a comprehensive overview of the ecology, physiology, biochemistry, and molecular biology of the mechanisms of osmotic and ionic regulation performed by the gill. The current concepts of the mechanisms of ion transport, the structural, biochemical, and molecular bases of systemic physiology, and the history of their development are discussed. The relationship between branchial ion transport and hemolymph acid-base regulation is also treated. In addition, the mechanisms of ammonia transport and excretion across the gill are discussed. And finally, the toxicology of heavy metal accumulation via the gill is reviewed in detail. PMID:23162474

NACA Zero Power Reactor Facility Hazards Summary

NASA Technical Reports Server (NTRS)

1957-01-01

The Lewis Flight Propulsion Laboratory of the National Advisory Committee for Aeronautics proposes to build a zero power research reactor facility which will be located in the laboratory grounds near Clevelaurd, Ohio. The purpose of this report is to inform the Advisory Commit tee on Reactor Safeguards of the U. S. Atomic Energy Commission in re gard to the design of the reactor facility, the cha,acteristics of th e site, and the hazards of operation at this location, The purpose o f this reactor is to perform critical experiments, to measure reactiv ity effects, to serve as a neutron source, and to serve as a training tool. The reactor facility is described. This is followed by a discu ssion of the nuclear characteristics and the control system. Site cha racteristics are then discussed followed by a discussion of the exper iments which may be conducted in the facility. The potential hazards of the facility are then considered, particularly, the maximum credib le accident. Finally, the administrative procedure is discussed.

The energy landscape of adenylate kinase during catalysis

DOE PAGES

Kerns, S. Jordan; Agafonov, Roman V.; Cho, Young-Jin; ...

2015-01-12

Kinases perform phosphoryl-transfer reactions in milliseconds; without enzymes, these reactions would take about 8,000 years under physiological conditions. Despite extensive studies, a comprehensive understanding of kinase energy landscapes, including both chemical and conformational steps, is lacking. In this paper, we scrutinize the microscopic steps in the catalytic cycle of adenylate kinase, through a combination of NMR measurements during catalysis, pre-steady-state kinetics, molecular-dynamics simulations and crystallography of active complexes. We find that the Mg 2+ cofactor activates two distinct molecular events: phosphoryl transfer (>10 5-fold) and lid opening (10 3-fold). In contrast, mutation of an essential active site arginine decelerates phosphorylmore » transfer 10 3-fold without substantially affecting lid opening. Finally, our results highlight the importance of the entire energy landscape in catalysis and suggest that adenylate kinases have evolved to activate key processes simultaneously by precise placement of a single, charged and very abundant cofactor in a preorganized active site.« less

Wind Power Potential at Abandoned Mines in Korea

NASA Astrophysics Data System (ADS)

jang, M.; Choi, Y.; Park, H.; Go, W.

2013-12-01

This study performed an assessment of wind power potential at abandoned mines in the Kangwon province by analyzing gross energy production, greenhouse gas emission reduction and economic effects estimated from a 600 kW wind turbine. Wind resources maps collected from the renewable energy data center in Korea Institute of Energy Research(KIER) were used to determine the average wind speed, temperature and atmospheric pressure at hub height(50 m) for each abandoned mine. RETScreen software developed by Natural Resources Canada(NRC) was utilized for the energy, emission and financial analyses of wind power systems. Based on the results from 5 representative mining sites, we could know that the average wind speed at hub height is the most critical factor for assessing the wind power potential. Finally, 47 abandoned mines that have the average wind speed faster than 6.5 m/s were analyzed, and top 10 mines were suggested as relatively favorable sites with high wind power potential in the Kangwon province.

Real-time soft error rate measurements on bulk 40 nm SRAM memories: a five-year dual-site experiment

NASA Astrophysics Data System (ADS)

Autran, J. L.; Munteanu, D.; Moindjie, S.; Saad Saoud, T.; Gasiot, G.; Roche, P.

2016-11-01

This paper reports five years of real-time soft error rate experimentation conducted with the same setup at mountain altitude for three years and then at sea level for two years. More than 7 Gbit of SRAM memories manufactured in CMOS bulk 40 nm technology have been subjected to the natural radiation background. The intensity of the atmospheric neutron flux has been continuously measured on site during these experiments using dedicated neutron monitors. As the result, the neutron and alpha component of the soft error rate (SER) have been very accurately extracted from these measurements, refining the first SER estimations performed in 2012 for this SRAM technology. Data obtained at sea level evidence, for the first time, a possible correlation between the neutron flux changes induced by the daily atmospheric pressure variations and the measured SER. Finally, all of the experimental data are compared with results obtained from accelerated tests and numerical simulation.

Evolution of the magnetic and structural properties of Fe 1 - x Co x V 2 O 4

DOE PAGES

Sinclair, R.; Ma, Jie; Cao, H. B.; ...

2015-10-12

The magnetic and structural properties of single-crystal Fe 1-xCo xV 2O 4 samples have been investigated by performing specific heat, susceptibility, neutron diffraction, and x-ray diffraction measurements. As the orbital-active Fe 2+ ions with larger ionic size are gradually substituted by the orbital-inactive Co 2+ ions with smaller ionic size, the system approaches the itinerant electron limit with decreasing V-V distance. Then, various factors such as the Jahn-Teller distortion and the spin-orbital coupling of the Fe 2+ ions on the A sites and the orbital ordering and electronic itinerancy of the V 3+ ions on the B sites compete withmore » each other to produce a complex magnetic and structural phase diagram. Finally, this phase diagram is compared to those of Fe 1-xMn xV 2O 4 and Mn 1-xCo xV 2O 4 to emphasize several distinct features.« less

Development of tacrine-bifendate conjugates with improved cholinesterase inhibitory and pro-cognitive efficacy and reduced hepatotoxicity.

PubMed

Cen, Juan; Guo, Huiyan; Hong, Chen; Lv, Jianwu; Yang, Yacheng; Wang, Ting; Fang, Dong; Luo, Wen; Wang, Chaojie

2018-01-20

A novel series of tacrine-bifendate (THA-DDB) conjugates (7a-e) were synthesized and evaluated as potential anti-Alzheimer's agents. These compounds showed potent cholinesterase and self-induced β-amyloid (Aβ) aggregation inhibitory activities. A Lineweaver-Burk plot and molecular modeling study showed that these compounds can target both catalytic active site (CAS) and peripheral anionic site (PAS) of acetylcholinesterase (AChE). The cytotoxicity of the conjugate 7d against PC12 and HepG2 cells and hepatotoxicity against human hepatocyte cell line (HL-7702) were found to be considerably less compared to THA. Moreover, treatment with 7d did not exhibit significant hepatotoxicity in mice. Finally, in vivo studies confirmed that 7d significantly ameliorates the cognitive performances of scopolamine-treated ICR mice. Therefore, 7d has high potential for the treatment of Alzheimer's disease and warrants further investigation. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Peritoneal Dialysis Catheter Insertion.

PubMed

Crabtree, John H; Chow, Kai-Ming

2017-01-01

The success of peritoneal dialysis as renal-replacement therapy depends on a well-functioning peritoneal catheter. Knowledge of best practices in catheter insertion can minimize the risk of catheter complications that lead to peritoneal dialysis failure. The catheter placement procedure begins with preoperative assessment of the patient to determine the most appropriate catheter type, insertion site, and exit site location. Preoperative preparation of the patient is an instrumental step in facilitating the performance of the procedure, avoiding untoward events, and promoting the desired outcome. Catheter insertion methods include percutaneous needle-guidewire with or without image guidance, open surgical dissection, peritoneoscopic procedure, and surgical laparoscopy. The insertion technique used often depends on the geographic availability of material resources and local provider expertise in placing catheters. Independent of the catheter implantation approach, adherence to a number of universal details is required to ensure the best opportunity for creating a successful long-term peritoneal access. Finally, appropriate postoperative care and catheter break-in enables a smooth transition to dialysis therapy. Copyright © 2017 Elsevier Inc. All rights reserved.

Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA.

PubMed

Guo, Shicheng; Diep, Dinh; Plongthongkum, Nongluk; Fung, Ho-Lim; Zhang, Kang; Zhang, Kun

2017-04-01

Adjacent CpG sites in mammalian genomes can be co-methylated owing to the processivity of methyltransferases or demethylases, yet discordant methylation patterns have also been observed, which are related to stochastic or uncoordinated molecular processes. We focused on a systematic search and investigation of regions in the full human genome that show highly coordinated methylation. We defined 147,888 blocks of tightly coupled CpG sites, called methylation haplotype blocks, after analysis of 61 whole-genome bisulfite sequencing data sets and validation with 101 reduced-representation bisulfite sequencing data sets and 637 methylation array data sets. Using a metric called methylation haplotype load, we performed tissue-specific methylation analysis at the block level. Subsets of informative blocks were further identified for deconvolution of heterogeneous samples. Finally, using methylation haplotypes we demonstrated quantitative estimation of tumor load and tissue-of-origin mapping in the circulating cell-free DNA of 59 patients with lung or colorectal cancer.

Flexible Friction Stir Joining Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feng, Zhili; Lim, Yong Chae; Mahoney, Murray

2015-07-23

Reported herein is the final report on a U.S. Department of Energy (DOE) Advanced Manufacturing Office (AMO) project with industry cost-share that was jointly carried out by Oak Ridge National Laboratory (ORNL), ExxonMobil Upstream Research Company (ExxonMobil), and MegaStir Technologies (MegaStir). The project was aimed to advance the state of the art of friction stir welding (FSW) technology, a highly energy-efficient solid-state joining process, for field deployable, on-site fabrications of large, complex and thick-sectioned structures of high-performance and high-temperature materials. The technology innovations developed herein attempted to address two fundamental shortcomings of FSW: 1) the inability for on-site welding andmore » 2) the inability to weld thick section steels, both of which have impeded widespread use of FSW in manufacturing. Through this work, major advance has been made toward transforming FSW technology from a “specialty” process to a mainstream materials joining technology to realize its pervasive energy, environmental, and economic benefits across industry.« less

Artificial Intelligence based technique for BTS placement

NASA Astrophysics Data System (ADS)

Alenoghena, C. O.; Emagbetere, J. O.; Aibinu, A. M.

2013-12-01

The increase of the base transceiver station (BTS) in most urban areas can be traced to the drive by network providers to meet demand for coverage and capacity. In traditional network planning, the final decision of BTS placement is taken by a team of radio planners, this decision is not fool proof against regulatory requirements. In this paper, an intelligent based algorithm for optimal BTS site placement has been proposed. The proposed technique takes into consideration neighbour and regulation considerations objectively while determining cell site. The application will lead to a quantitatively unbiased evaluated decision making process in BTS placement. An experimental data of a 2km by 3km territory was simulated for testing the new algorithm, results obtained show a 100% performance of the neighbour constrained algorithm in BTS placement optimization. Results on the application of GA with neighbourhood constraint indicate that the choices of location can be unbiased and optimization of facility placement for network design can be carried out.

The coexistence temperature of hydrogen clathrates: A molecular dynamics study

NASA Astrophysics Data System (ADS)

Luis, D. P.; Romero-Ramirez, I. E.; González-Calderón, A.; López-Lemus, J.

2018-03-01

Extensive molecular dynamics simulations in the equilibrium isobaric-isothermal (NPT) ensemble were developed to determine the coexistence temperatures of the water hydrogen mixture using the direct coexistence method. The water molecules were modeled using the four-site TIP4P/Ice analytical potential, and the hydrogen molecules were described using a three-site potential. The simulations were performed at different pressures (p = 900, 1500, 3000, and 4000 bars). At each pressure, a series of simulations were developed at different temperatures (from 230 to 270 K). Our results followed a line parallel to the experimental coexistence temperatures and underestimated these temperatures by approximately 25 K in the investigated range. The final configurations could or could not contain a fluid phase depending on the pressure, in accordance with the phase diagram. In addition, we explored the dynamics of the H2 molecules through clathrate hydrate cages and observed different behaviors of the H2 molecules in the small cages and the large cages of the sII structure.

Alveolar ridge reduction after tooth extraction in adolescents: an animal study

PubMed Central

Sun, Zongyang; Herring, Susan W.; Tee, Boon Ching; Gales, Jordan

2013-01-01

Objective The mechanism for tooth extraction induced residual alveolar ridge reduction (RRR) during adolescence is poorly understood. This study investigated the alveolar bone morphology, growth, resorption and functional loading at normal and extraction sites using an adolescent pig model. Design Sixteen 3-month-old pigs were divided into two groups – immediate post-extraction (IE) and 6-week post-extraction (SE). The IE group received an extraction of one deciduous mandibular molar, immediately followed by a final experiment to record masseter muscle EMGs and strains from the buccal surface of the extraction and contralateral non-extraction sites during function (mastication). The SE group was given the same tooth extraction, then kept for 6 weeks before the same final functional recording as the IE group. Both groups also received baseline (pre-extraction) EMGs and fluorescent vital stains 10 and 3 days before the final functional recording. Immediately after the final functional recording, animals were euthanized and alveolar bone specimens from extraction and contralateral non-extraction sites were collected and used to analyze alveolar bone morphology, apposition and resorption based on fluorescent and hematoxylin and eosin stained histological sections. Results At control sites (IE-extraction, IE-non-extraction and SE-non-extraction), the alveolar ridges grew gingivally and buccally. Bone formation characterized the buccal surface and lingual bundle bone, whereas resorption characterized the lingual surface and buccal bundle bone. The SE-extraction sites showed three major alterations: convergence of the buccal and lingual gingival crests, loss of apposition on the lingual bundle bone, and decelerated growth at the entire buccal surface. These alterations likely resulted from redirected crestal growth as part of the socket healing process, loss of tongue pressure to the lingual side of the teeth which normally provides mechanical stimulation for dental arch expansion, and masticatory underloading during the initial post-extraction period, respectively. Conclusions These data indicate that the initial phase of RRR in adolescents is a product of modified growth, not resorption, possibly because of decreased mechanical stimulation at the extraction site. PMID:23380583

78 FR 67881 - Nondiscrimination on the Basis of Disability in Air Travel: Accessibility of Web Sites and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-12

... corresponding accessible pages on a mobile Web site by one year after the final rule's effective date; and (3... Mobile Web site conformant with any of the following standards: WCAG 1.0, WCAG 2.0 at Level A, existing Section 508 standards, or Mobile Web Best Practices (MWBP) 1.0 (if applicable). Two of the options they...

Contemporary approaches to congestion pricing : lessons learned from the national evaluation of congestion pricing strategies at six sites.

DOT National Transportation Integrated Search

2015-08-01

This document represents the final report of the national evaluation of congestion reduction strategies at six sites that received federal funding under the Urban Partnership Agreement (UPA) and Congestion Reduction Demonstration (CRD) programs. The ...

SUPERFUND TREATABILITY CLEARINGHOUSE: FINAL REPORT: SOIL TREATMENT PILOT STUDY BRIO/DOP SITE

EPA Science Inventory

Bench and pilot-scale studies were conducted to demonstrate the feasibility of using solid-phase biodegradation for destroying portions of organic constituents present in the soil. The predominant constituents at the BRIO DOP site located in Texas were volatile compounds such...

Ecological Risk Assessment Guidance for Superfund: Process for Designing and Conducting Ecological Risk Assessments - Interim Final

EPA Pesticide Factsheets

This document provides guidance to site managers and Remedial Project Managers who are legally responsible for the management of a site on how to design and conduct technically defensible ecological risk assessments for the Superfund program.

Tailgate test kit for determining appropriate sediment reducing chemicals and dose rates : final report.

DOT National Transportation Integrated Search

2017-07-01

This study develops a Tailgate Test Kit to be used in the field to test flocculants for reducing turbidity in construction stormwater discharge. Turbidity of stormwater runoff at construction sites varies depending on which site soils are exposed to ...

Issuance of Final Guidance: Ecological Risk Assessment and Risk Management Principles for Superfund Sites, October 7, 1999

EPA Pesticide Factsheets

This guidance is intended to help Superfund risk managers make ecological risk management decisions that are based on sound science, consistent across Regions, and present a characterization of site risks that is transparent to the public.

Synthetic Minor NSR Permit: BP America Production Company - Treating Site #8 Central Delivery Point

EPA Pesticide Factsheets

This page contains the response to public comments and the final synthetic minor NSR permit for the BP America Production Company, Treating Site #8 Central Delivery Point, located on the Southern Ute Indian Reservation in La Plata County, CO.

Superfund Record of Decision (EPA Region 7): Lehigh Portland Cement Company, Mason City, IA. (First remedial action), June 1991. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-06-28

The Lehigh Portland Cement site is composed of two areas: the 150-acre Lehigh Portland Cement Company (LPCC) cement production facility, and the 410-acre Lime Creek Nature Center (LCNC), in Mason, Gordo County, Iowa. The site overlies an aquifer that serves as a source of water for 12 nearby wells; and municipal water is obtained from a deeper aquifer. Calmus Creek borders the site and discharges to the Winnebago River, located within a mile of the site. From 1911 to the present, the LPCC has manufactured cement products. In 1981, hydrochemical tests of Blue Waters Pond on the LPCC area indicatedmore » high alkalinity. The Record of Decision (ROD) addresses the Cement Kiln Dust ground water, and surface water as a final remedy. Elevated pH of ground water and surface water also is of potential concern. The selected remedial action for all are included.« less

Superfund Record of Decision (EPA Region 5): Allied Chemical and Ironton Coke, Ironton, OH. (Second remedial action), December 1990. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-12-28

The 95-acre Allied Chemical and Ironton Coke site is comprised of a former coke plant and an operating tar plant in Ironton, Lawrence County, Ohio. The site is located within a coal mining region, and surrounding land use is predominantly industrial and residential. The ROD addresses contamination at all areas not previously addressed, and provides a final remedy at the site. The primary contaminants of concern affecting the soil, sediment, and ground water are VOCs including benzene; other organics including PAHs and phenols; metals including arsenic; and other inorganics including cyanide. The selected remedial action for this site includes excavatingmore » and incinerating onsite approximately 122,000 cubic yards of waste material from Lagoon 5, and 31,000 cubic yards of waste coal, followed by onsite waste fuel recovery and disposing of the residual ash offsite; in-situ bioremediation of approximately 475,000 cubic yards of waste material from Lagoons.« less

National Wind Tunnel Complex (NWTC)

NASA Technical Reports Server (NTRS)

1996-01-01

The National Wind Tunnel Complex (NWTC) Final Report summarizes the work carried out by a unique Government/Industry partnership during the period of June 1994 through May 1996. The objective of this partnership was to plan, design, build and activate 'world class' wind tunnel facilities for the development of future-generation commercial and military aircraft. The basis of this effort was a set of performance goals defined by the National Facilities Study (NFS) Task Group on Aeronautical Research and Development Facilities which established two critical measures of improved wind tunnel performance; namely, higher Reynolds number capability and greater productivity. Initial activities focused upon two high-performance tunnels (low-speed and transonic). This effort was later descoped to a single multipurpose tunnel. Beginning in June 1994, the NWTC Project Office defined specific performance requirements, planned site evaluation activities, performed a series of technical/cost trade studies, and completed preliminary engineering to support a proposed conceptual design. Due to budget uncertainties within the Federal government, the NWTC project office was directed to conduct an orderly closure following the Systems Design Review in March 1996. This report provides a top-level status of the project at that time. Additional details of all work performed have been archived and are available for future reference.

Post-Flight EDL Entry Guidance Performance of the 2011 Mars Science Laboratory Mission

NASA Technical Reports Server (NTRS)

Mendeck, Gavin F.; McGrew, Lynn Craig

2012-01-01

The 2011 Mars Science Laboratory was the first successful Mars mission to attempt a guided entry which safely delivered the rover to a final position approximately 2 km from its target within a touchdown ellipse of 19.1 km x 6.9 km. The Entry Terminal Point Controller guidance algorithm is derived from the final phase Apollo Command Module guidance and, like Apollo, modulates the bank angle to control the range flown. For application to Mars landers which must make use of the tenuous Martian atmosphere, it is critical to balance the lift of the vehicle to minimize the range error while still ensuring a safe deploy altitude. An overview of the process to generate optimized guidance settings is presented, discussing improvements made over the last nine years. Key dispersions driving deploy ellipse and altitude performance are identified. Performance sensitivities including attitude initialization error and the velocity of transition from range control to heading alignment are presented. Just prior to the entry and landing of MSL in August 2012, the EDL team examined minute tuning of the reference trajectory for the selected landing site, analyzed whether adjustment of bank reversal deadbands were necessary, the heading alignment velocity trigger was in union with other parameters to balance the EDL risks, and the vertical L/D command limits. This paper details a preliminary postflight assessment of the telemetry and trajectory reconstruction that is being performed, and updates the information presented in the former paper Entry Guidance for the 2011 Mars Science Laboratory Mission (AIAA Atmospheric Flight Mechanics Conference; 8-11 Aug. 2011; Portland, OR; United States)

Health assessment for Midwest Industrial Waste Disposal Company, Inc. (Midco II) NPL (National Priorities List) Site, 5900 Industrial Highway, Gary, Indiana, Region 5. CERCLIS No. IND980679559. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1989-04-12

The 7-acre Midco II Site is located at 5900 Industrial Highway, Gary, Indiana. The site is listed on the National Priorities List. Various heavy metals, inorganic, and organic compounds were found in the media on-site. The environmental media of concern at the site are ground water, surface water, and soil. Although access to the Midco II site is restricted, the contaminants detected on-site will continue to migrate and may pose health threats until remedial activities are completed. Therefore, the Midco II site poses a potential health concern until an evaluation of the site is completed and remedial activities are chosen.

From Information Management to Information Visualization

PubMed Central

Karami, Mahtab

2016-01-01

Summary Objective The development and implementation of a dashboard of medical imaging department (MID) performance indicators. Method Several articles discussing performance measures of imaging departments were searched for this study. All the related measures were extracted. Then, a panel of imaging experts were asked to rate these measures with an open ended question to seek further potential indicators. A second round was performed to confirm the performance rating. The indicators and their ratings were then reviewed by an executive panel. Based on the final panel’s rating, a list of indicators to be used was developed. A team of information technology consultants were asked to determine a set of user interface requirements for the building of the dashboard. In the first round, based on the panel’s rating, a list of main features or requirements to be used was determined. Next, Qlikview was utilized to implement the dashboard to visualize a set of selected KPI metrics. Finally, an evaluation of the dashboard was performed. Results 92 MID indicators were identified. On top of this, 53 main user interface requirements to build of the prototype of dashboard were determined. Then, the project team successfully implemented a prototype of radiology management dashboards into study site. The visual display that was designed was rated highly by users. Conclusion To develop a dashboard, management of information is essential. It is recommended that a quality map be designed for the MID. It can be used to specify the sequence of activities, their related indicators and required data for calculating these indicators. To achieve both an effective dashboard and a comprehensive view of operations, it is necessary to design a data warehouse for gathering data from a variety of systems. Utilizing interoperability standards for exchanging data among different systems can be also effective in this regard. PMID:27437043