32 CFR 516.32 - Requests for indemnification.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 3 2011-07-01 2009-07-01 true Requests for indemnification. 516.32 Section 516.32 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES... allied papers. (c) Supervisory and SJA procedures. The request for indemnification will be submitted...

32 CFR 516.32 - Requests for indemnification.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 3 2014-07-01 2014-07-01 false Requests for indemnification. 516.32 Section 516.32 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES... allied papers. (c) Supervisory and SJA procedures. The request for indemnification will be submitted...

32 CFR 516.32 - Requests for indemnification.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 3 2013-07-01 2013-07-01 false Requests for indemnification. 516.32 Section 516.32 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES... allied papers. (c) Supervisory and SJA procedures. The request for indemnification will be submitted...

32 CFR 516.32 - Requests for indemnification.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 3 2012-07-01 2009-07-01 true Requests for indemnification. 516.32 Section 516.32 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES... allied papers. (c) Supervisory and SJA procedures. The request for indemnification will be submitted...

32 CFR 516.23 - Litigation reports.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Litigation reports. 516.23 Section 516.23 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Reporting Legal Proceedings to HQDA § 516.23 Litigation reports. The SJA or...

32 CFR 513.1 - General.

Code of Federal Regulations, 2013 CFR

2013-07-01

... news media organizations to the unit, installation, or command public affairs officer for response. (6... received from news media organizations. (ii) Coordinate with the SJA before making any response. (e) Policy... remain proof of indebtedness until— (i) Made good. (ii) Proven to be the error of the financial...

32 CFR 513.1 - General.

Code of Federal Regulations, 2012 CFR

2012-07-01

... news media organizations to the unit, installation, or command public affairs officer for response. (6... received from news media organizations. (ii) Coordinate with the SJA before making any response. (e) Policy... remain proof of indebtedness until— (i) Made good. (ii) Proven to be the error of the financial...

32 CFR 513.1 - General.

Code of Federal Regulations, 2011 CFR

2011-07-01

... news media organizations to the unit, installation, or command public affairs officer for response. (6... received from news media organizations. (ii) Coordinate with the SJA before making any response. (e) Policy... remain proof of indebtedness until— (i) Made good. (ii) Proven to be the error of the financial...

32 CFR 513.1 - General.

Code of Federal Regulations, 2010 CFR

2010-07-01

... news media organizations to the unit, installation, or command public affairs officer for response. (6... received from news media organizations. (ii) Coordinate with the SJA before making any response. (e) Policy... remain proof of indebtedness until— (i) Made good. (ii) Proven to be the error of the financial...

32 CFR 516.21 - Litigation against government contractors.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 3 2012-07-01 2009-07-01 true Litigation against government contractors. 516.21... government contractors. (a) General. A contract might require that the government reimburse a contractor (or... with the government requires reimbursement for adverse judgments or costs of the litigation, the SJA or...

32 CFR 516.50 - Interference with mission.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 3 2011-07-01 2009-07-01 true Interference with mission. 516.50 Section 516.50 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND... will seriously interfere with the accomplishment of a military mission, the SJA or legal adviser will...

32 CFR 516.50 - Interference with mission.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 3 2014-07-01 2014-07-01 false Interference with mission. 516.50 Section 516.50 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND... will seriously interfere with the accomplishment of a military mission, the SJA or legal adviser will...

32 CFR 516.50 - Interference with mission.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 3 2012-07-01 2009-07-01 true Interference with mission. 516.50 Section 516.50 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND... will seriously interfere with the accomplishment of a military mission, the SJA or legal adviser will...

32 CFR 516.50 - Interference with mission.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 3 2013-07-01 2013-07-01 false Interference with mission. 516.50 Section 516.50 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND... will seriously interfere with the accomplishment of a military mission, the SJA or legal adviser will...

32 CFR 516.50 - Interference with mission.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Interference with mission. 516.50 Section 516.50 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND... will seriously interfere with the accomplishment of a military mission, the SJA or legal adviser will...

Medical Surveillance Monthly Report (MSMR). Volume 16, Number 2, February 2009

DTIC Science & Technology

2009-02-01

Urethritis, non-gonococcal (NGU). Reporting location Arthropod-borne Sexually transmitted Environmental Lyme disease Malaria Chlamydia Gonorrhea Syphilis...transmitted Environmental Lyme disease Malaria Chlamydia Gonorrhea Syphilis‡ Urethritis§ Cold Heat 2008 2009 2008 2009 2008 2009 2008 2009 2008 2009 2008...Environmental Lyme disease Malaria Chlamydia Gonorrhea Syphilis‡ Urethritis§ Cold Heat 2008 2009 2008 2009 2008 2009 2008 2009 2008 2009 2008 2009 2008

Discovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomes.

PubMed

Lee, Erinna F; Clarke, Oliver B; Evangelista, Marco; Feng, Zhiping; Speed, Terence P; Tchoubrieva, Elissaveta B; Strasser, Andreas; Kalinna, Bernd H; Colman, Peter M; Fairlie, W Douglas

2011-04-26

Schistosomiasis is an infectious disease caused by parasites of the phylum platyhelminthe. Here, we describe the identification and characterization of a Bcl-2-regulated apoptosis pathway in Schistosoma japonicum and S. mansoni. Genomic, biochemical, and cell-based mechanistic studies provide evidence for a tripartite pathway, similar to that in humans including BH3-only proteins that are inhibited by prosurvival Bcl-2-like molecules, and Bax/Bak-like proteins that facilitate mitochondrial outer-membrane permeabilization. Because Bcl-2 proteins have been successfully targeted with "BH3 mimetic" drugs, particularly in the treatment of cancer, we investigated whether schistosome apoptosis pathways could provide targets for future antischistosomal drug discovery efforts. Accordingly, we showed that a schistosome prosurvival protein, sjA, binds ABT-737, a well-characterized BH3 mimetic. A crystal structure of sjA bound to a BH3 peptide provides direct evidence for the feasibility of developing BH3 mimetics to target Bcl-2 prosurvival proteins in schistosomes, suggesting an alternative application for this class of drugs beyond cancer treatment.

Discovery and molecular characterization of a Bcl-2–regulated cell death pathway in schistosomes

PubMed Central

Lee, Erinna F.; Clarke, Oliver B.; Evangelista, Marco; Feng, Zhiping; Speed, Terence P.; Tchoubrieva, Elissaveta B.; Strasser, Andreas; Kalinna, Bernd H.; Colman, Peter M.; Fairlie, W. Douglas

2011-01-01

Schistosomiasis is an infectious disease caused by parasites of the phylum platyhelminthe. Here, we describe the identification and characterization of a Bcl-2–regulated apoptosis pathway in Schistosoma japonicum and S. mansoni. Genomic, biochemical, and cell-based mechanistic studies provide evidence for a tripartite pathway, similar to that in humans including BH3-only proteins that are inhibited by prosurvival Bcl-2–like molecules, and Bax/Bak-like proteins that facilitate mitochondrial outer-membrane permeabilization. Because Bcl-2 proteins have been successfully targeted with “BH3 mimetic” drugs, particularly in the treatment of cancer, we investigated whether schistosome apoptosis pathways could provide targets for future antischistosomal drug discovery efforts. Accordingly, we showed that a schistosome prosurvival protein, sjA, binds ABT-737, a well-characterized BH3 mimetic. A crystal structure of sjA bound to a BH3 peptide provides direct evidence for the feasibility of developing BH3 mimetics to target Bcl-2 prosurvival proteins in schistosomes, suggesting an alternative application for this class of drugs beyond cancer treatment. PMID:21444803

32 CFR 842.121 - Referring a claim to the US Attorney.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Referring a claim to the US Attorney. 842.121 Section 842.121 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE CLAIMS AND... to the US Attorney. Only HQ USAF/JACC authorizes referral of a claim to the US Attorney. The base SJA...

32 CFR 842.121 - Referring a claim to the US Attorney.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Referring a claim to the US Attorney. 842.121... to the US Attorney. Only HQ USAF/JACC authorizes referral of a claim to the US Attorney. The base SJA...-case basis, HQ USAF/JACC will authorize referral of a case to the US Attorney by telephone. ...

Comparative characterization of microRNAs in Schistosoma japonicum schistosomula from Wistar rats and BALB/c mice.

PubMed

Han, Hongxiao; Peng, Jinbiao; Hong, Yang; Fu, Zhiqiang; Lu, Ke; Li, Hao; Zhu, Chuangang; Zhao, Qiuhua; Lin, Jiaojiao

2015-07-01

More than 40 kinds of mammals in China are known to be naturally infected with Schistosoma japonicum (S. japonicum) (Peng et al. Parasitol Res 106:967-76, 2010). Compared with permissive BALB/c mice, rats are less susceptible to S. japonicum infection and are considered to provide an unsuitable microenvironment for parasite growth and development. MicroRNAs (miRNAs), via the regulation of gene expression at the transcriptional and post-transcriptional levels, may be responsible for developmental differences between schistosomula in these two rodent hosts. Solexa deep-sequencing technology was used to identify differentially expressed miRNAs from schistosomula isolated from Wistar rats and BALB/c mice 10 days post-infection. The deep-sequencing analysis revealed that nearly 40 % of raw reads (10.37 and 10.84 million reads in schistosomula isolated from Wistar rats and BALB/c mice, respectively) can be mapped to selected mirs in miRBase or in species-specific genomes. Further analysis revealed that several miRNAs were differentially expressed in schistosomula isolated from these two rodents; 18 were downregulated (by <2-fold) and 23 were up-regulated (>2-fold) (expression levels in rats compare with those in mice). Additionally, three novel miRNAs were primarily predicted and identified. Among the 41 differentially expressed miRNAs, 4 miRNAs had been identified with specific functions in schistosome development or host-parasite interaction, such as sexual maturation (sja-miR-1, sja-miR-7-5p), embryo development (sja-miR-36-3p) in schistosome, and pathogenesis of schistosomiasis (sja-bantam). Then, the target genes were mapped, filtered, and correlated with a set of genes that were differentially expressed genes in schistosomula isolated from mice and rats, which we identified in a S. japonicum oligonucleotide microarray analysis in a previous study. Gene Ontology (GO) analysis of the predicted target genes of 13 differentially expressed miRNAs revealed that they

Detecting and Jamming Dynamic Communication Networks in Anti-Access Environments

DTIC Science & Technology

2011-03-01

P.M. Pardalos, Y. Ye. and C.W. Commander (eds) V. Boginski. Sensors: Theory , Algorithms, and Applications. Springer, to appear in 2009. [21] Joseph C...Sumeetpal S. Singh. Nikolaos Kantas , Ba-Ngu Vo, Arnaud Doucet, and Robin J. Evans. Simulation-based optimal sensor scheduling with application to...observer trajectory planning. Aotomatica, 43(5):817-830, 2007. [27] Anthony Man-Cho So and Yinyu Ye. Theory of semidefinite programming for sensor network

Analysis of USAREUR Family Housing.

DTIC Science & Technology

1985-04-01

Standard Installation/Division Personnel System SJA ................ Staff Judge Advocate SPSS ............... Statistical Package for the...for Projecting Family Housing Requirements. a. Attempts to define USAREUR’s programmable family housing deficit Sbased on the FHS have caused anguish ...responses using the Statistical Package for the Social Sciences ( SPSS ) computer program. E-2 ANNEX E RESPONSE TO ESC HOUSING QUESTIONNAIRE Section Page I

Replacing the CCSDS Telecommand Protocol with the Next Generation Uplink (NGU)

NASA Technical Reports Server (NTRS)

Kazz, Greg J.; Greenberg, Ed; Burleigh, Scott C.

2012-01-01

The current CCSDS Telecommand (TC) Recommendations 1-3 have essentially been in use since the early 1960s. The purpose of this paper is to propose a successor protocol to TC. The current CCSDS recommendations can only accommodate telecommand rates up to approximately 1 mbit/s. However today's spacecraft are storehouses for software including software for Field Programmable Gate Arrays (FPGA) which are rapidly replacing unique hardware systems. Changes to flight software occasionally require uplinks to deliver very large volumes of data. In the opposite direction, high rate downlink missions that use acknowledged CCSDS File Delivery Protocol (CFDP)4 will increase the uplink data rate requirements. It is calculated that a 5 mbits/s downlink could saturate a 4 kbits/s uplink with CFDP downlink responses: negative acknowledgements (NAKs), FINISHs, End-of-File (EOF), Acknowledgements (ACKs). Moreover, it is anticipated that uplink rates of 10 to 20 mbits/s will be required to support manned missions. The current TC recommendations cannot meet these new demands. Specifically, they are very tightly coupled to the Bose-Chaudhuri-Hocquenghem (BCH) code in Ref. 2. This protocol requires that an uncorrectable BCH codeword delimit the TC frame and terminate the randomization process. This method greatly limits telecom performance since only the BCH code can support the protocol. More modern techniques such as the CCSDS Low Density Parity Check (LDPC)5 codes can provide a minimum performance gain of up to 6 times higher command data rates as long as sufficient power is available in the data. This paper will describe the proposed protocol format, trade-offs, and advantages offered, along with a discussion of how reliable communications takes place at higher nominal rates.

JPRS Report, East Asia, Southeast Asia, Vietnam: Tap Chi Cong San, No. 9, September 1990

DTIC Science & Technology

1991-04-15

34 (1853) in which Victor Hugo condemned the dictator Louis Bonaparte, who strangled the republic and established the Second Empire in 1851. And we...clearly in the recent works of Nguyen Minh Chau, Ma Van Khang, Le Luu, Mai Ngu, Do Chu, Khuat Quang Thuy, Nguyen Tri Huan, Tran Thanh Giao, Trung...have called our literature "mandarin literature" during the time of Le Thanh Tong and "palace literature." (SONG HUONG No 31, 1988) They have put

Trans World Tidal Gravity Profile.

DTIC Science & Technology

1976-12-01

LABORATORY AIR FORCE SYSTEMS COMMAN D __ UNITEI) STATES AIR FO RC E HANSCOIVI AFB , MASSACHUSETTS 0173 1 ‘ S ~~~~~ V — (~~~) REPORT DOCUMENTATION PAGE...the fundamental station established at Canberra. Uniformity is maintained with the Brussels fundamental station. It is assessed that the...as well as Canberra and Alice Springs still operatin ~; in 1976. Four new stations are described here Kuala Lumpur (~ a1a’~sja) The gravimeter

A Random Finite Set Approach to Space Junk Tracking and Identification

DTIC Science & Technology

2014-09-03

Final 3. DATES COVERED (From - To) 31 Jan 13 – 29 Apr 14 4. TITLE AND SUBTITLE A Random Finite Set Approach to Space Junk Tracking and...01-2013 to 29-04-2014 4. TITLE AND SUBTITLE A Random Finite Set Approach to Space Junk Tracking and Identification 5a. CONTRACT NUMBER FA2386-13...Prescribed by ANSI Std Z39-18 A Random Finite Set Approach to Space Junk Tracking and Indentification Ba-Ngu Vo1, Ba-Tuong Vo1, 1Department of

Development and Application of Energetic Actuators for Shear and Vortex Dominated Flow Control

DTIC Science & Technology

2014-03-06

NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON a. REPORT b. ABSTRACT c . THIS PAGE 19b. TELEPHONE NUMBER (include area code...of the air inside of the SparkJet cavity prior to heating. C is the capacitance across the sustain electrodes, V is the voltage across the sustain...in wind tunnel; a) tunnel test section; b) tunnel ceiling; c ) SparkJet actuator. Figure 2.8: Bottom and rear views of the three-SJA assembly

Meatal Swabs Contain Less Cellular Material and Are Associated with a Decrease in Gram Stain Smear Quality Compared to Urethral Swabs in Men.

PubMed

Jordan, Stephen J; Schwebke, Jane R; Aaron, Kristal J; Van Der Pol, Barbara; Hook, Edward W

2017-07-01

Urethral swabs are the samples of choice for point-of-care Gram stain testing to diagnose Neisseria gonorrhoeae infection and nongonococcal urethritis (NGU) in men. As an alternative to urethral swabs, meatal swabs have been recommended for the collection of urethral discharge to diagnose N. gonorrhoeae and Chlamydia trachomatis infection in certain populations by nucleic acid amplification testing (NAAT), as they involve a less invasive collection method. However, as meatal swabs could be sampling a reduced surface area and result in fewer collected epithelial cells compared to urethral swabs, the adequacy of meatal swab specimens to collect sufficient cellular material for Gram stain testing remains unknown. We enrolled 66 men who underwent either urethral or meatal swabbing and compared the cellular content and Gram stain failure rate. We measured the difference in swab cellular content using the Cepheid Xpert CT/NG sample adequacy control crossing threshold (SAC CT ) and determined the failure rate of Gram stain smears (GSS) due to insufficient cellular material. In the absence of discharge, meatal smears were associated with a significant reduction in cellular content ( P = 0.0118), which corresponded with a GSS failure rate significantly higher than that for urethral swabs (45% versus 3%, respectively; P < 0.0001). When discharge was present, there was no difference among results from urethral and meatal swabs. Therefore, if GSS testing is being considered for point-of-care diagnosis of N. gonorrhoeae infection or NGU in men, meatal swabs should be avoided in the absence of a visible discharge. Copyright © 2017 American Society for Microbiology.

Intelligent lightening system of urban and rural road traffic based on pyroelectric infrared detector

NASA Astrophysics Data System (ADS)

Miao, Man-Xiang

2007-12-01

By using the photo-voltage characteristics of pyroelectric infrared detector to fulfill signal acquisition, the detecting signal is processed with the core of a single chip microprocessor AT89C51. AT89C51 controls the CAN bus controller SJA1000/transceiver 82C250 to structure CAN bus communication system to transmit data through serial interface MAX232 connected with PC. The intelligent lightening system of urban and rural road traffic was carried out. In this paper, its construction and part's methods of hardware and software design were introduced in detail.

Advanced Modified High Performance Synthetic Jet Actuator with Curved Chamber

NASA Technical Reports Server (NTRS)

Xu, Tian-Bing (Inventor); Su, Ji (Inventor); Jiang, Xiaoning (Inventor)

2014-01-01

The advanced modified high performance synthetic jet actuator with optimized curvature shape chamber (ASJA-M) is a synthetic jet actuator (SJA) with a lower volume reservoir or chamber. A curved chamber is used, instead of the conventional cylinder chamber, to reduce the dead volume of the jet chamber and increase the efficiency of the synthetic jet actuator. The shape of the curvature corresponds to the maximum displacement (deformation) profile of the electroactive diaphragm. The jet velocity and mass flow rate for the ASJA-M will be several times higher than conventional piezoelectric actuators.

Biology and Trapping of Stable Flies (Diptera: Muscidae) Developing in Pineapple Residues (Ananas comosus) in Costa Rica

PubMed Central

Solórzano, José-Arturo; Gilles, Jeremie; Bravo, Oscar; Vargas, Cristina; Gomez-Bonilla, Yannery; Bingham, Georgina V.; Taylor, David B.

2015-01-01

Pineapple production in Costa Rica increased nearly 300-fold during the last 30 yr, and >40,000 hectares of land are currently dedicated to this crop. At the end of the pineapple cropping cycle, plants are chopped and residues incorporated into the soil in preparation for replanting. Associated with increased pineapple production has been a large increase in stable fly, Stomoxys calcitrans (L.), populations. Stable flies are attracted to, and oviposit in, the decomposing, chopped pineapple residues. In conjunction with chemical control of developing larvae, adult trapping is an important control strategy. In this study, four blue-black fabric traps, Nzi, Vavoua, Model H, and Ngu, were compared with a white sticky trap currently used for stable fly control in Costa Rica. Overall, the white sticky trap caught the highest number of stable flies, followed by the Nzi, Vavoua, Model H, and Ngu. Collections on the white sticky trap increased 16 d after residues were chopped; coinciding with the expected emergence of flies developing in the pineapple residues. During this same time period, collections in the blue-black fabric traps decreased. Sex ratio decreased from >7:1 (females:males) 3–7 d after chopping to 1:1 at 24–28 d. White sticky, Nzi and Vavoua traps collected similar numbers of colonizing flies 3–7 d after residues were chopped. However, white sticky traps collected more flies once emergence from the pineapple residues began. Although white sticky traps collected more flies than fabric traps, they remain labor intensive and environmentally unsound because of their disposable and nonbiodegradable nature. PMID:26454479

Understanding Grammars through Diachronic Change

PubMed Central

Madariaga, Nerea

2017-01-01

In this paper, I will vindicate the importance of syntactic change for the study of synchronic stages of natural languages, according to the following outline. First, I will analyze the relationship between the diachrony and synchrony of grammars, introducing some basic concepts: the notions of I-language/E-language, the role of Chomsky's (2005) three factors in language change, and some assumptions about language acquisition. I will briefly describe the different approaches to syntactic change adopted in generative accounts, as well as their assumptions and implications (Lightfoot, 1999, 2006; van Gelderen, 2004; Biberauer et al., 2010; Roberts, 2012). Finally, I will illustrate the convenience of introducing the diachronic dimension into the study of at least certain synchronic phenomena with the help of a practical example: variation in object case marking of several verbs in Modern Russian, namely, the verbs denoting avoidance and the verbs slušat'sja “obey” and dožidat'sja “expect,” which show two object case-marking patterns, genitive case in standard varieties and accusative case in colloquial varieties. To do so, I will review previous descriptive and/or functionalist accounts on this or equivalent phenomena (Jakobson, 1984 [1936]; Clancy, 2006; Nesset and Kuznetsova, 2015a,b). Then, I will present a formal—but just synchronic—account, applying Sigurðsson (2011) hypothesis on the expression of morphological case to this phenomenon. Finally, I will show that a formal account including the diachronic dimension is superior (i.e., more explanative) than purely synchronic accounts. PMID:28824474

[Late complications following Björk-Shiley and St. Jude Medical heart valve replacement].

PubMed

Horstkotte, D; Körfer, R; Budde, T; Haerten, K; Schulte, H D; Bircks, W; Loogen, F

1983-05-01

Valve-related complications after Björk-Shiley mitral (n = 475), aortic (n = 424), or mitral-aortic implantation (n = 119) were compared to complications after St. Jude mitral (n = 173), aortic (n = 152), and St. Jude mitral and aortic (n = 63) replacements. The 1,018 consecutive patients with Björk-Shiley valves had been operated upon between 1974 and 1982, those with St. Jude valves between 1978 and 1982. All patients were placed on anticoagulant therapy with phenprocoumon early after operation and no significant intergroup differences in the effectiveness of the anticoagulant therapy were found. At a comparable follow-up time of approximately 23 months, 24 major thromboembolic episodes were observed after Björk-Shiley mitral (BSM) and 3 after St. Jude mitral valve implantation (SJM), corresponding to a thromboembolic rate of 2.82/100 patient years with BSM and 0.93/100 patient years with SJM. After aortic valve replacements, 1.93 events in 100 patient years occurred after Björk-Shiley aortic (BSA) and 0.73 after St. Jude aortic implantation (SJA). In patients with double valve replacements, these rates were 3.2 (BSM + BSA) and 0.88 (SJM + SJA), respectively. The cerebral vessels were involved in 52% and the arteries of the extremities in 22% of these major events. Six Björk-Shiley prostheses had to be replaced because of valve thrombosis. The overall incidence of severe hemorrhagic complications was 2.94/100 patient years in BSM and 1.79 in SJM. After aortic valve replacement, we found rates of 1.80/100 patient years (BSA) and 2.57/100 patient years (SJA), respectively. Intravascular hemolysis no longer seems to be a significant clinical problem. However, indications of red cell damage after heart valve replacement were significantly greater in patients with perivalvular leakage, valve thrombosis, or dysfunction than in those with normally functioning prostheses. Reoperations were necessary because of valve thrombosis (0.46%), perivalvular leakage (2

Summer heat: a cross-sectional analysis of seasonal differences in sexual behaviour and sexually transmissible diseases in Melbourne, Australia.

PubMed

Cornelisse, Vincent J; Chow, Eric P F; Chen, Marcus Y; Bradshaw, Catriona S; Fairley, Christopher K

2016-06-01

To date, no study has correlated seasonal differences in sexual behaviour with the seasonal differences in sexually transmitted infections (STIs); and no seasonal study of STIs has been conducted in the southern hemisphere. Our study aimed to describe seasonal differences in sexual behaviour and correlate this with seasonal differences in STI diagnoses in Melbourne, Australia. This was a cross-sectional study of individuals attending the Melbourne Sexual Health Centre over a 9-year period from 2006 to 2014. We conducted separate analyses for men who have sex with men (MSM) and men who have sex with women (MSW), and women. Seasonal patterns of sexual behaviour and STI positivity were examined within each group. All groups reported a higher number of partners over the preceding three months for consultations in summer compared with winter (MSM mean 5.48 vs 5.03; MSW mean 2.46 vs 2.31; women mean 1.83 vs 1.72). Urethral gonorrhoea diagnoses among MSM were higher in summer compared with winter (OR 1.23, 95% CI 1.04 to 1.46). Similarly, non-gonococcal urethritis (NGU) diagnoses among MSW were the highest in summer (OR 1.11, 95% CI 1.03 to 1.20), but there was no seasonal difference in NGU diagnoses when we adjusted for partner numbers. In women, pelvic inflammatory disease (PID) diagnoses peaked in autumn, when rates were higher than in winter (OR 1.30, 95% CI 1.09 to 1.55). Our results describe a peak in sexual partner number and STI diagnoses during consultations in summer in men and a rise in PID in autumn in women. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Azithromycin treatment failure for Chlamydia trachomatis among heterosexual men with nongonococcal urethritis

PubMed Central

Kissinger, Patricia; White, Scott; Manhart, Lisa E.; Schwebke, Jane; Taylor, Stephanie N; Mena, Leandro; Khosropour, Christine M; Wilcox, Larissa; Schmidt, Norine; Martin, David H

2016-01-01

Background Three recent prospective studies have suggested that the 1 g dose of azithromycin for Chlamydia trachomatis (Ct) was less effective than expected, reporting a wide range of treatment failure rates (5.8%–22.6%). Reasons for the disparate results could be attributed to geographic or methodological differences. The purpose of this study was to re-examine the studies and attempt to harmonize methodologies to reduce misclassification as a result of false positives from early test-of-cure (TOC) or reinfection as a result of sexual exposure rather than treatment failure. Methods Men who had sex with women, who received 1 g azithromycin under directly observed therapy (DOT) for presumptive treatment of nongonococcal urethritis (NGU) with confirmed Ct were included. Baseline screening was performed on urethral swabs or urine and TOC screening was performed on urine using nucleic acid amplification tests (NAAT). Post-treatment vaginal sexual exposure was elicited at TOC. Data from the three studies was obtained and re-analyzed. Rates of Ct re-test positive were examined for all cases and a sensitivity analysis was conducted to either reclassify potential false positives/reinfections as negative or remove them from the analysis. Results The crude treatment failure rate was 12.8% (31/242). The rate when potential false positives/reinfections were reclassified as negative was 6.2% (15/242) or when these were excluded from analysis was 10.9% (15/138). Conclusion In these samples of men who have sex with women with Ct-related NGU, azithromycin treatment failure was between 6.2% and 12.8%. This range of failure is lower than previously published but higher than the desired World Health Organization’s target chlamydia treatment failure rate of < 5%. PMID:27631353

What would be missed if we didn't screen men who have sex with men for oral chlamydia trachomatis? A cross-sectional study.

PubMed

Loomba, Priya; Knight, Vickie; McNulty, Anna

2016-04-01

Background This study aimed to describe oropharyngeal chlamydia (OCT) in gay and bisexually active men (GBM) attending a large urban sexual health clinic in Sydney and determine what proportion of cases would be missed if screening was not routine. Retrospective data were extracted for all GBM with a positive OCT result between 1 October 2012 and 31 April 2014. The control group consisted of patients who had a negative OCT result on their first visit during the study period, and each patient was only counted once. A total of 74 of 2920 GBM (0.03, 95% CI: 0.02-0.03) were diagnosed with OCT. The 2920 GBM had a total of 11226 OCT tests performed, demonstrating OCT test positivity of 0.006 (95% CI: 0.005-0.008). A total of 62 sexually transmissible infections (STIs) were diagnosed at other sites: 34 rectal chlamydia (CT), 12 throat gonorrohea (GC), 7 urine CT, 7 rectal GC, 1 infectious syphilis and 1 non-gonoccal urethritis (NGU) case. Of the 74 OCT cases, 56 (0.76, 95% CI: 0.64-0.85) were treated with Azithromycin; 51 (69%) as part of standard treatment for their STI co-infection (34 rectal CT, 12 throat GC, 7 urine CT, 7 rectal GC, 1 NGU case) and a further five (7%) were treated as contacts. The remaining 18 people (0.24, 95% CI: 0.15-0.36) would not have been treated unless they were tested specifically for OCT. Overall, two-thirds of the OCT cases received appropriate treatment and only a small number of cases would have been missed had routine screening not been performed. With an extremely low overall test positivity of 0.6%, screening for OCT at our service adds little to population level health control.

Biology and trapping of stable flies (Diptera: Muscidae) developing in pineapple residues (Ananas comosus) in Costa Rica.

PubMed

Solórzano, José-Arturo; Gilles, Jeremie; Bravo, Oscar; Vargas, Cristina; Gomez-Bonilla, Yannery; Bingham, Georgina V; Taylor, David B

2015-01-01

Pineapple production in Costa Rica increased nearly 300-fold during the last 30 yr, and >40,000 hectares of land are currently dedicated to this crop. At the end of the pineapple cropping cycle, plants are chopped and residues incorporated into the soil in preparation for replanting. Associated with increased pineapple production has been a large increase in stable fly, Stomoxys calcitrans (L.), populations. Stable flies are attracted to, and oviposit in, the decomposing, chopped pineapple residues. In conjunction with chemical control of developing larvae, adult trapping is an important control strategy. In this study, four blue-black fabric traps, Nzi, Vavoua, Model H, and Ngu, were compared with a white sticky trap currently used for stable fly control in Costa Rica. Overall, the white sticky trap caught the highest number of stable flies, followed by the Nzi, Vavoua, Model H, and Ngu. Collections on the white sticky trap increased 16 d after residues were chopped; coinciding with the expected emergence of flies developing in the pineapple residues. During this same time period, collections in the blue-black fabric traps decreased. Sex ratio decreased from >7:1 (females:males) 3-7 d after chopping to 1:1 at 24-28 d. White sticky, Nzi and Vavoua traps collected similar numbers of colonizing flies 3-7 d after residues were chopped. However, white sticky traps collected more flies once emergence from the pineapple residues began. Although white sticky traps collected more flies than fabric traps, they remain labor intensive and environmentally unsound because of their disposable and nonbiodegradable nature. Published by Oxford University Press on behalf of the Entomological Society of America 2015. This work is written by US Government employees and is in the public domain in the US.

Production Suitability of an Electroform Conductive Wax Process for the Manufacture of Fluidic Systems

DTIC Science & Technology

1975-11-01

2l«^,«’) T>SL JI To «ATt JlOO «n «t* in. fTA * 3^ "PlbiA-e-*^ To wia •^ -IZ0"L6, (.21 >To «AUVK« ^-^STRlP^TiM e.ax>s «»I To RATft...8 C B E U^T^SJA ani« fMD ran © HMajrwelL "« TEftT COkTTRoL ’PAMB.V, ■•i’r^rT" I’» 1 Mj u 56- £ to i. — TOO*.« r7gi^iiiiniM.gi 4|ji»" mkd

Research and design of intelligent distributed traffic signal light control system based on CAN bus

NASA Astrophysics Data System (ADS)

Chen, Yu

2007-12-01

Intelligent distributed traffic signal light control system was designed based on technologies of infrared, CAN bus, single chip microprocessor (SCM), etc. The traffic flow signal is processed with the core of SCM AT89C51. At the same time, the SCM controls the CAN bus controller SJA1000/transceiver PCA82C250 to build a CAN bus communication system to transmit data. Moreover, up PC realizes to connect and communicate with SCM through USBCAN chip PDIUSBD12. The distributed traffic signal light control system with three control styles of Vehicle flux, remote and PC is designed. This paper introduces the system composition method and parts of hardware/software design in detail.

Performance evaluation of automated urine microscopy as a rapid, non-invasive approach for the diagnosis of non-gonococcal urethritis.

PubMed

Pond, Marcus J; Nori, Achyuta V; Patel, Sheel; Laing, Ken; Ajayi, Margarita; Copas, Andrew J; Butcher, Philip D; Hay, Phillip; Sadiq, Syed Tariq

2015-05-01

Gram-stained urethral smear (GSUS), the standard point-of-care test for non-gonococcal urethritis (NGU) is operator dependent and poorly specific. The performance of rapid automated urine flow cytometry (AUFC) of first void urine (FVU) white cell counts (UWCC) for predicting Mycoplasma genitalium and Chlamydia trachomatis urethral infections was assessed and its application to asymptomatic infection was evaluated. Receiver operating characteristic curve analysis, determining FVU-UWCC threshold for predicting M. genitalium or C. trachomatis infection was performed on 208 'training' samples from symptomatic patients and subsequently validated using 228 additional FVUs obtained from prospective unselected patients. An optimal diagnostic threshold of >29 UWC/µL gave sensitivities and specificities for either infection of 81.5% (95% CI 65.1% to 91.6%) and 85.8% (79.5% to 90.4%), respectively, compared with 86.8% (71.1% to 95%) and 64.7% (56.9% to 71.7%), respectively, for GSUS, using the training set samples. FVU-UWCC demonstrated sensitivities and specificities of 69.2% (95% CI 48.1% to 84.9%) and 92% (87.2% to 95.2%), respectively, when using validation samples. In asymptomatic patients where GSUS was not used, AUFC would have enabled more infections to be detected compared with clinical considerations only (71.4% vs 28.6%; p=0.03). The correlation between UWCC and bacterial load was stronger for M. genitalium compared with C. trachomatis (τ=0.426, p≤0.001 vs τ=0.295, p=0.022, respectively). AUFC offers improved specificity over microscopy for predicting C. trachomatis or M. genitalium infection. Universal AUFC may enable non-invasive diagnosis of asymptomatic NGU at the PoC. The degree of urethral inflammation exhibits a stronger association with pathogen load for M. genitalium compared with C. trachomatis. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Sexually transmitted diseases in Poland in 2011.

PubMed

Majewski, Sławomir; Rudnicka, Iwona

2013-01-01

Was to assess epidemiological situation of sexually transmitted diseases in Poland in 2011. Analysis of the data on prevalence of syphilis, gonorrhoea, non-gonococcal urethritis, genital herpes and genital warts was gathered from yearly reports MZ-14 from several didtricts. In 2011 there were 841 reported cases of all types of syphilis, which was higher by 24 than in 2010. Within the reported cases, 554 cases were of early syphilis, 274 cases of late syphilis, and 11 cases of congenital syphilis. Syphilis during pregnancy and childbirth was reported in 13 women. The highest incidence of syphilis in 2011, similarly to previous years was in Mazowieckie district (4.7/100,000) and the lowest in Swietokrzyskie district (0.2/100,000), the average in a whole country accounted to 2.2/100,000. In 2011 there were 351 cases of gonorrhoea reported, which was higher by 77 cases than reported in the previous year. The highest incidence was reported in Mazowieckie voivodeship. Non-gonococcal urethritis -NGU was identified in 484 persons; this was less by 294 cases than reported in the previous year. The highest incidence rate was reported in Dolnoślaskie voivodeship 9.6/100,000. There were 428 cases of genital warts reported which was less by 174 cases than reported in 2010. The highest incidence rate was reported in Mazowieckie voivodeship, Warminsko- Mazurskie voivodeship and Kujawsko-Pomorskie voivodeship. As in previous years the most unfavourable epidemiological situation in terms of all registered sexually transmitted diseases was in Mazowieckie voivodeship. In 2011 among sexually transmitted diseases NGU and genital warts were reported in lower numbers then in previous year. In the same time numbers of reported cases of gonorrhoea and syphilis increased. There is a continued decrease in the number of serological tests done for syphilis. Epidemiological indicators of treatment for gonorrhoea and syphilis are very low for number of years. The epidemiological data is

Integrated actuation and energy harvesting in prestressed piezoelectric synthetic jets

NASA Astrophysics Data System (ADS)

Mane, Poorna

With the looming energy crisis compounded by the global economic downturn there is an urgent need to increase energy efficiency and to discover new energy sources. An approach to solve this problem is to improve the efficiency of aerodynamic vehicles by using active flow control tools such as synthetic jet actuators. These devices are able to reduce fuel consumption and streamlined vehicle design by reducing drag and weight, and increasing maneuverability. Hence, the main goal of this dissertation is to study factors that affect the efficiency of synthetic jets by incorporating energy harvesting into actuator design using prestressed piezoelectric composites. Four state-of-the-art piezoelectric composites were chosen as active diaphragms in synthetic jet actuators. These composites not only overcome the inherent brittle and fragile nature of piezoelectric materials but also enhance domain movement which in turn enhances intrinsic contributions. With these varying characteristics among different types of composites, the intricacies of the synthetic jet design and its implementation increases. In addition the electrical power requirements of piezoelectric materials make the new SJA system a coupled multiphysics problem involving electro-mechanical and structural-fluid interactions. Due to the nature of this system, a design of experiments approach, a method of combining experiments and statistics, is utilized. Geometric and electro-mechanical factors are investigated using a fractional factorial design with peak synthetic jet velocity as a response variable. Furthermore, energy generated by the system oscillations is harvested with a prestressed composite and a piezo-polymer. Using response surface methodology the process is optimized under different temperatures and pressures to simulate harsh environmental conditions. Results of the fractional factorial experimental design showed that cavity dimensions and type of signal used to drive the synthetic jet actuator

Characterisation of glycoconjugate sugar residues in the vomeronasal organ of the armadillo Chaetophractus villosus (Mammalia, xenarthra)

PubMed Central

CARMANCHAHI, P. D.; FERRARI, C. C.; ALDANA MARCOS, H. J.; AFFANNI, J. M.; SONEZ, C. A.; PAZ, D. A.

2000-01-01

Conventional carbohydrate histochemistry and the binding patterns of 21 lectins were analysed to characterise the glycoconjugate content in the components of the vomeronasal organ of the armadillo Chaetophractus villosus. The mucomicrovillous complex of the sensory epithelium bound most of the lectins studied. No reaction was observed with Con A, PSA, S-Con A and SBA, and the sustentacular cells were stained with UEA-I, DSL, LEL, STL and Con A. The vomeronasal receptor neurons were labelled with S-WGA, WGA, PNA, UEA-I, STL, Con A, S-Con A, ECL and RCA120. The basal cell layer reacted with S-WGA, WGA, LCA, UEA-I, DSL, LEL, STL, Con A, JAC and VVA. The nonsensory epithelium exhibited a differential staining in relation to the different components. The mucociliary complex stained with ECL, DBA, JAC, RCA120, STL, LCA, PHA-E, PHA-L, LEL, BSL-I and VVA. However, SJA and UEA-I stained the mucus complex lining a subpopulation of columnar cells. The cytoplasm and cell membranes of columnar cells was labelled with DBA, DSL and LCA. The apical region of these cells exhibited moderate reactivity with LEL and SJA. None of the lectins bound specifically to secretory granules of the nonsecretory cells. Basal cells of the nonsensory epithelium were labelled with DSL, LEL, LCA, BSL-I and STL. The vomeronasal glands showed a positive reaction with WGA, DSL, LEL, LCA, DBA, PNA, RCA120 and SBA. Subpopulations of acinar cells were observed with ECL, S-WGA, Con A, S-Con A and DBA. PNA and RCA120 stained the cells lining the glandular ducts. In comparison with previous results obtained in the olfactory mucosa of the same group of armadillos, the carbohydrate composition of the vomeronasal organ sensory epithelium differed from the olfactory sensory epithelium. This is probably related to the different nature of molecules involved in the perireceptor processes. PMID:10853958

The SPARDIG project - Transforming analogue sparker records from the Norwegian continental shelf into SEG-Y format, first results

NASA Astrophysics Data System (ADS)

Schaming, Marc; Rise, Leif; Chand, Shyam; Reidulv, Bøe; Terje Osmundsen, Per; Redfield, Tim

2017-04-01

A large number of sparker lines were acquired on the Norwegian continental shelf during the years 1970-1982, by IKU (Sintef Petroleum Research). The responsibility of the analogue seismic database was transferred to NGU in 1998; this included storage of the physical data (original paper rolls and half-scale film copies) and the digital navigation database. The data (from 60°N to 71°30N) were in the early eighties subdivided in 6 data packages, and offered for sale to oil companies as half scale folded paper copies (25 cm width). Navigation applied was mainly Decca Main Chain. The 2014-2016 SPARDIG project (Chand et al., 2016) was supported by NGU, AkerBP (Det Norske), Lundin Norway and the Seabed Project. In the project, IPGS has transformed 374 rolls of analogue sparker lines in 17 different surveys into SEG-Y format. The total length of converted survey lines is 31 261 kilometers. Rolls were scanned at 600 dpi and converted into SEG-Y using the SeisTrans (Caldera software) application (Miles et al., 2007). SeisTrans uses interactive, iterative and repeatable steps in a dedicated graphics window. A first step allows definition of axes and scales, then record time lines (horizontal TWT times and navigation time lines down the record) are picked and removed, and traces are defined. At this step, control tools are available to ensure the quality of the traces. After that, navigation information extracted and interpolated from excel files are added to trace headers. A continuous QC process allows production of SEG-Y files directly readable by interpretation software. The SEG-Y data will be delivered to the Norwegian Discos National Repository (https://portal.diskos.cgg.com/whereoil-data/) but access will be restricted to participants until 1st April 2019. IKU sparker lines have higher resolution than conventional 2D lines, but the penetration is limited. The data sets are complementary to each other. In 2D seismic lines, it is often difficult to delineate units in

Design of a CAN bus interface for photoelectric encoder in the spaceflight camera

NASA Astrophysics Data System (ADS)

Sun, Ying; Wan, Qiu-hua; She, Rong-hong; Zhao, Chang-hai; Jiang, Yong

2009-05-01

In order to make photoelectric encoder usable in a spaceflight camera which adopts CAN bus as the communication method, CAN bus interface of the photoelectric encoder is designed in this paper. CAN bus interface hardware circuit of photoelectric encoder consists of CAN bus controller SJA 1000, CAN bus transceiver TJA1050 and singlechip. CAN bus interface controlling software program is completed in C language. A ten-meter shield twisted pair line is used as the transmission medium in the spaceflight camera, and speed rate is 600kbps.The experiments show that: the photoelectric encoder with CAN bus interface which has the advantages of more reliability, real-time, transfer rate and transfer distance overcomes communication line's shortcomings of classical photoelectric encoder system. The system works well in automatic measuring and controlling system.

How Much Did Maine's Molocket and Metallak Know about Rapid Climate Change? Did They Utilize Psychological Strategies and Cover Stories to Conceal Their Impact Communities, Observational Sites and Data Collection?

NASA Astrophysics Data System (ADS)

Bates, Tiffany R.; Mc Leod, Roger D.; Mc Leod, David M.

2003-10-01

The Pequakets Molocket (adherent of God La[ngued]oc Christ Cathar Spirit-signal) and Metallak operated in NH and the western border area of ME, during the early 1800s. Molocket requested shelter in South Paris, ME during a powerful thunderstorm. Denied access, she cursed that area. Our interests have led us to recognize that there may be psychological reasons that deception is good strategic procedure for concealing valuable activities associated with impact power groups striving to protect their operating turf. Many sites associated with tradition-respecting Native Americans are quite electromagnetically responsive to climate change. Metallak (mathematician-applied astronomer God Spirit-signal) is purported to have driven off his son over purloined furs; that elder son then operated among the MiKmaw/Micmacs of ME and the Canadian Maritimes. They are purported to make the weather. Information protection and surreptitious data collection may indicate an impact groups concealed interests.

Does the Internet assist clients to carry out contact tracing? A randomized controlled trial using web-based information.

PubMed

Tomnay, J E; Pitts, M K; Kuo, T C; Fairley, C K

2006-06-01

The primary outcome was to determine the acceptability of the Internet, specifically a website for use in standard partner notification. A secondary objective was to determine if a website would enhance the outcomes of currently used partner notification methods. In a randomized control trial, 105 participants diagnosed with chlamydia and non-gonoccocal urethritis (NGU) were randomized and 97 completed the study. About 30% of participants were provided a standard partner letter and 70% were provided the standard partner letter and website. All participants reported that their partners had no objections to the website (0%, 95% confidence interval [CI] 0-5%). There were no complaints received from any partner. The odds ratio for contacting partners was not significantly different between the two groups of participants. The results of this study indicate that providing a website with specific information about the infection to which a partner has been exposed is not harmful.

Advanced high performance horizontal piezoelectric hybrid synthetic jet actuator

NASA Technical Reports Server (NTRS)

Xu, Tian-Bing (Inventor); Jiang, Xiaoning (Inventor); Su, Ji (Inventor)

2012-01-01

The present invention comprises a high performance, horizontal, zero-net mass-flux, synthetic jet actuator for active control of viscous, separated flow on subsonic and supersonic vehicles. The present invention is a horizontal piezoelectric hybrid zero-net mass-flux actuator, in which all the walls of the chamber are electrically controlled synergistically to reduce or enlarge the volume of the synthetic jet actuator chamber in three dimensions simultaneously and to reduce or enlarge the diameter of orifice of the synthetic jet actuator simultaneously with the reduction or enlargement of the volume of the chamber. The present invention is capable of installation in the wing surface as well as embedding in the wetted surfaces of a supersonic inlet. The jet velocity and mass flow rate for the SJA-H will be several times higher than conventional piezoelectric actuators.

Construction and Effect of New Mechanical Structure in Traditional Nitroguanidine Propellants

NASA Astrophysics Data System (ADS)

Sun, Pengfei; Liao, Xin; Wang, Zeshan

2017-07-01

In order to improve the mechanical properties of nitroguanidine propellants, spheroidized nitroguanidine (SNGu) was mixed up with needle-shaped NGu (NSNGu) at different mass ratios. The results from tensile/compression tests showed that the addition of SNGu could improve compression properties of nitroguanidine propellants. At the NSNGu to SNGu ratio of 8:2, compression properties of the propellants exhibit an excellent promotion with the maximum increase of 25.2% at -40°C comparing against the value of the traditional propellants. Meanwhile, tensile properties of the new propellants at the same ratio were nearly equal to those of traditional propellants. The impacts of the morphology of NGus on the distribution density and orientation of the NGus were investigated by scanning electron microscopy (SEM). The aforementioned mechanical behavior of nitroguanidine propellants could be well explained by the results of closed-bomb tests. The difference of the total heat effect observed in the Differential Scanning Calorimeter (DSC) tests of the two NGus was calculated to be only 1.5%.

Implementation of numerical simulations for rockfall hazard mapping in the Norddal municipality, Norway.

NASA Astrophysics Data System (ADS)

Yugsi Molina, Freddy Xavier; Oppikofer, Thierry; Otterå, Solveig; Hermanns, Reginald; Taurisano, Andrea; Wasrud, Jaran; Are Jensen, Odd; Rødseth Kvakland, Marte

2013-04-01

The Norwegian Water Resources and Energy Directorate (NVE) in cooperation with the Geological Survey of Norway (NGU) are implementing a nationwide program to systematically produce hazard maps for rockfalls, debris flows and snow avalanches in steep terrains. Activities during this program mapping are being carried out by both institutions, and for some areas, outsourced to the private sector. The results presented in this contribution focus on the rockfall component only, and are part of the hazard mapping activities carried out by NGU. Results from all parties involved will further lead in future, in combination with the components on debris flows and snow avalanches, to the preparation of guidelines for landslide hazard mapping. Those will be presented and recommended for the use of private consultants that work on municipality level. The first goal of the project is the preparation of hazard maps for critical areas where a large number of people are exposed to the threat of such type of mass movements. Results from a pilot area in Sylte (Norddal municipality) were presented in the EGU general assembly in 2012. The main objective of this contribution is to present the first finished rockfall hazard maps generated by NGU during the execution of the program. The results presented in this contribution were obtained for the Norddal municipality (Møre og Romsdal county). The area was selected based on the hazard mapping plan of Norway published in 2011, where Norddal is considered a priority area. The area is located in a valley over-steepened by glacial erosion that is characterized by high cliffs of medium to coarse-grained quartz-dioritic to granitic gneisses of Proterozoic age. Multiple scree deposits product of older and recent rockfall activity can be seen along the bottom at both valley flanks. Sylte, the main locality in the Norddal municipality, is located at the valley outlet to the fjord. Several other smaller localities are found along the valley. A

European Plate Observing System - the Arctic dimension and the Nordic collaboration

NASA Astrophysics Data System (ADS)

Atakan, K.; Heikkinen, P.; Juhlin, C.; Thybo, H.; Vogfjord, K.

2012-04-01

strong motion networks monitor seismic activity and hazard in the North Atlantic. Vigorous volcanic activity along the plate boundary in Iceland and associated hazards are monitored by the Icelandic, seismic, geodetic, meteorological and hydrological networks. Recent eruptions, like the 2010 Eyjafjallajökull eruptions have demonstrated the far-reaching hazard to aviation caused by volcanic eruptions in Iceland. The high-sensitivity seismic and geodetic networks of Sweden monitor isostatic rebound of Fennoscandia. In this context, the varied Nordic monitoring networks provide a significant contribution to the main objectives of EPOS. There are already existing links with the other ESFRI initiatives where strong Nordic participation is established, such as SIOS and EMSO. As such EPOS provides the necessary platform to collaborate and develop an important Nordic dimension in the European Research Area. There is a long tradition of collaboration at the governmental level between the Nordic countries, Norway, Sweden, Denmark, Finland and Iceland. Within the fields of research and education, the Nordic Ministries have a dedicated program, where research networks are being promoted. Recently a Nordic collaborative network in seismology, "NordQuake" (coordinated by Denmark) was established within this program. This collaboration which is now formalized and supported by the Nordic Ministries is based on a cooperation which was initiated more than 40 years ago, where annual Nordic Seminars in seismology (previously on detection seismology) was the central element. EPOS Nordic collaboration, building upon a long lasting history, has a significant potential for synergy effects in the region and therefore represents an important dimension within EPOS. Nordic EPOS Team: Lars Ottemöller (UiB), Mathilde B. Sørensen (UiB), Louise W. Bjerrum (UiB), Conrad Lindholm (Norsar), Halfdan Kjerulf (SK), Amir Kaynia (NGI), Valerie Maupin (UiO), Tor Langeland (CMR), Joerg Ebbing (NGU), John

Populations of domesticated cattle and buffalo in the Western Forest Complex of Thailand and their possible impacts on the wildlife community.

PubMed

Chaiyarat, Rattanawat; Srikosamatara, Sompod

2009-03-01

The Western Forest Complex (WEFCOM) of Thailand is comprised of many protected areas and has one of the highest wildlife populations in the country. Populations of wildlife in the WEFCOM have decreased dramatically over recent years. Rapid economic development has resulted in the conversion of forest into agricultural and pastoral land, which has directly and indirectly impacted the wildlife community. This research aimed to evaluate populations of domesticated cattle (Bos indicus) and buffalo (Bubalus bubalis) in the WEFCOM and their possible impacts on the wildlife community. Domesticated cattle and buffalo keepers from 1561 (or 3.3%) of houses in and near WEFCOM were interviewed. The average number of animals per household was 15.6 cattle and 8.5 buffalo. Most villagers released domesticated cattle and buffalo to forage in the protected areas. This tended to have a high impact on the wildlife community in Huai Kha Khaeng Wildlife Sanctuary and Tungyai Naresuan Wildlife Sanctuary. The least impacted areas were Luam Khlong Ngu National Park, Thong Pha Phum National Park and Chaleam Ratanakosin National Park. With a high risk to the wildlife community, law enforcement should be used in combination with a certain level of co-management with local communities.

The DYNAFLUX / DYNACOLD (Dynamics, Fluxes, Stability, Succession and Landscape Formation in Cold Environments) Network (2004-2017)

NASA Astrophysics Data System (ADS)

Beylich, Achim A.

2017-04-01

There is a wide range of high-latitude and high-altitude cold climate landscapes within Europe, covering a significant proportion of the total land surface area. This spectrum of defined cold-climate landscapes represents a variety of stages of deglaciation history and landscape formation. We can find landscapes at different levels of postglacial stabilization which is providing the unique opportunity to study the interactions between geo-, bio-, social and socio-economic systems at the land surface. The DYNAFLUX / DYNACOLD Network (2004-2017) bridges across the geo-, bio-, social and socio-economic sciences in order to analyze the complex dynamics of adjustment, stabilization, succession and landscape formation during and after ice retreat and under ongoing anthropogenic influences. The network provides a multidisciplinary forum where researchers come together and discuss. In addition, this network is linking a number of other scientific networks, working groups and programs and creates an umbrella network and a forum for sharing knowledge and experience. The scientific focus of DYNAFLUX / DYNACOLD is also relevant for a number of end users, including risk and vulnerability assessment, sustainable land use, land management and conservation. In addition, present key questions related to environmental change like, e.g., hazards, permafrost degradation and loss of biodiversity are addressed and discussed. Further information is found under http://www.ngu.no/sediflux.

Liposomes as potential carrier system for targeted delivery of polyene antibiotics.

PubMed

Naik, Suresh R; Desai, Sandhya K; Shah, Priyank D; Wala, Santosh M

2013-09-01

The development of new therapeutic modalities involves the use of drug carrier, such as liposomes, which can modify pharmacokinetic and bio-distribution of drug profile. Polyene antibiotics incorporation into liposomes improves its availability at the site, bio-distribution and therapeutic index mainly through the engulfment of liposomes by circulating monocytes/macrophages and transportation to the site of infection. Polyene antibiotics (AmB, SJA-95, HA-1-92) and other antibiotics (streptomycin, tobramycin, quinolones, anti-tubercular and anti-cancer drugs), liposomal preparations are described with possible advantages from therapeutic efficacy and toxicity point of view. The polyene macrolide antibiotics liposomal preparations proved to be more effective in the treatment of systemic mycosis. The AmB-cyclodextrin derivatives inclusion complex is a major breakthrough in liposomal preparation which can be converted into aqueous phase of liposome. Liposomal drug incorporated preparation has been one of the important areas of research for developing the existing polyene antibiotics into useful chemotherapeutic agents in clinical medicine. In recent past other antibiotics have also been incorporated into liposomes using wide variety of materials, phosphatidylethanolamine derivatives (pegylated liposomes, enzyme sensitive conjugates, fluidosomes of anti-cancer drugs and poly lactic/glycolic acid microspheres for anti-tuberculosis drugs). In addition, attempts were also made to extend the receptor mediated drug targeting and to review some relevant patents.

Automated paleomagnetic and rock magnetic data acquisition with an in-line horizontal "2G" system

NASA Astrophysics Data System (ADS)

Mullender, Tom A. T.; Frederichs, Thomas; Hilgenfeldt, Christian; de Groot, Lennart V.; Fabian, Karl; Dekkers, Mark J.

2016-09-01

Today's paleomagnetic and magnetic proxy studies involve processing of large sample collections while simultaneously demanding high quality data and high reproducibility. Here we describe a fully automated interface based on a commercial horizontal pass-through "2G" DC-SQUID magnetometer. This system is operational at the universities of Bremen (Germany) and Utrecht (Netherlands) since 1998 and 2006, respectively, while a system is currently being built at NGU Trondheim (Norway). The magnetometers are equipped with "in-line" alternating field (AF) demagnetization, a direct-current bias field coil along the coaxial AF demagnetization coil for the acquisition of anhysteretic remanent magnetization (ARM) and a long pulse-field coil for the acquisition of isothermal remanent magnetization (IRM). Samples are contained in dedicated low magnetization perspex holders that are manipulated by a pneumatic pick-and-place-unit. Upon desire samples can be measured in several positions considerably enhancing data quality in particular for magnetically weak samples. In the Bremen system, the peak of the IRM pulse fields is actively measured which reduces the discrepancy between the set field and the field that is actually applied. Techniques for quantifying and removing gyroremanent overprints and for measuring the viscosity of IRM further extend the range of applications of the system. Typically c. 300 paleomagnetic samples can be AF demagnetized per week (15 levels) in the three-position protocol. The versatility of the system is illustrated by several examples of paleomagnetic and rock magnetic data processing.

AB38. Microorganisms in Chronic prostatitis in outpatient clinic Mongolia

PubMed Central

Samdankhuu, Khongorzul; Sanjmyatav, Purevjal; Damiran, Naransukh; Naidan, Nansalmaa

2014-01-01

Background Recent years, morbidity of chronic prostatis is increasing in Mongolia. Most common cause of the chronic prostatis is Non-Gonococcal Urethritis (NGU) such as chlamydia trachomatis, mycoplasma hominis, mycoplasma genitalium, ureaplasma urealyticum and ureaplasma parvum or mixed infections. Purpose The purpose of the study was to research possible relationships between signs or symptoms of the chronic prostatitis and its cause. Method A total of 466 males who have possible signs of chronic prostatitis were enrolled in the study. All patients were checked for urinalysis and expressed prostate secretion (EPS) and Polymerase Chain Reaction (PCR) of EPS detection for neisser a gonorrhea, chlamydia trachomatis, mycoplasma hominis, mycoplasma genitalium, ureaplasma urealyticum and ureaplasma parvum at an outpatient center of andrology office, Ulaanbaatar, Mongolia. Results Two hundred and eighty three of all participants have positive PCR results. Mean age of in our study was 33.1±8 years. U. realyticum was the most common (48.6%), followed by M. hominis and C. trachomatis mixed infection. In Mach, April and August were highest episodes of morbidity were registered 16.2%, 11.69% and 10.71%. Chronic pelvic pain syndrome and lower urinary tract symptoms were the most common complaints of main reason to visit outpatient clinic. Conclusions U. urealyticum was most common infection detected by PCR analyses among men who have chronic prostatitis, who have chronic pelvic pain syndrome. Further research is needed to determine if there are associations between signs or symptoms and cause of the chronic prostatis.

Community Assembly and Ecology of Activated Sludge under Photosynthetic Feast-Famine Conditions.

PubMed

Oyserman, Ben O; Martirano, Joseph M; Wipperfurth, Spenser; Owen, Brian R; Noguera, Daniel R; McMahon, Katherine D

2017-03-21

Here, we demonstrate that photosynthetic oxygen production under light-dark and feast-famine cycles with no mechanical aeration and negligible oxygen diffusion is able to maintain phosphorus cycling activity associated with the enrichment of polyphosphate accumulating organisms (PAOs). We investigate the ecology of this novel system by conducting a time series analysis of prokaryotic and eukaryotic biodiversity using the V3-V4 and V4 regions of the 16S and 18S rRNA gene sequences, respectively. In the Eukaryotic community, the initial dominant alga observed was Desmodesmus. During operation, the algal community became a more diverse consortium of Desmodesmus, Parachlorella, Characiopodium, and Bacillariophytina. In the Prokaryotic community, there was an initial enrichment of the PAO Candidatus Accumulibacter phosphatis (Accumulibacter) Acc-SG2, and the dominant ammonia-oxidizing organism was Nitrosomonas oligotropha; however, these populations decreased in relative abundance, becoming dominated by Accumulibacter Acc-SG3 and Nitrosomonas ureae. Furthermore, functional guilds that were not abundant initially became enriched including the putative Cyanobacterial PAOs Obscuribacterales and Leptolyngbya and the H 2 -oxidizing denitrifying autotroph Sulfuritalea. After a month of operation, the most-abundant prokaryote belonged to an uncharacterized clade of Chlorobi classified as Chlorobiales;SJA-28 Clade III, the first reported enrichment of this lineage. This experiment represents the first investigation into the ecological interactions and community assembly during photosynthetic feast-famine conditions. Our findings suggest that photosynthesis may provide sufficient oxygen to drive polyphosphate cycling.

Comparative Gut Microbiomes of Four Species Representing the Higher and the Lower Termites.

PubMed

Su, LiJuan; Yang, LeLe; Huang, Shi; Su, XiaoQuan; Li, Yan; Wang, FengQin; Wang, EnTao; Kang, Ning; Xu, Jian; Song, AnDong

2016-01-01

Aiming at learning the association between the gut microbiota and termites with different diet habits and phylogenetic positions, the gut bacteria of three populations for each of the two higher termites (wood-feeding Mironasutitermes shangchengensis and fungus-feeding Odontotermes formosanus) and two wood-feeding lower termites (Tsaitermes ampliceps and Reticulitermes flaviceps) were analyzed by high-throughput 454 pyrosequencing of 16S V1-V3 amplicons. As results, 132 bacterial genera and some unidentified operational taxonomic units within 29 phyla in the gut bacteria were detected, with Spirochaetes (11-55%), Firmicutes (7-18%), Bacteroidetes (7-31%), and Proteobacteria (8-14%) as the main phyla, and Treponema, TG5, Dysgonomonas, Tannerella, za29, Lactococcus, Pseudomonas, and SJA-88 as the common genera in all the four termites. The diversity of gut bacterial communities in the higher termite guts was significantly greater than that in the lower termites; while the gut microbiota in M. shangchengensis (wood-feeding higher termite) was more similar to those of the wood-feeding lower termites rather than that of O. formosanus (fungus-feeding higher termite), and phylum Spirochaetes and nitrogen-fixing bacteria were super-dominant in the wood-feeding termites, despite of their phylogenetic relations. This study reported for the first time the gut bacterial communities for the termites of M. shangchengensis and T. ampliceps and the comparative analyses showed that the gut microbial communities varied according to the phylogeny and the diet habits of termites. © The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America.

Substrate-Driven Convergence of the Microbial Community in Lignocellulose-Amended Enrichments of Gut Microflora from the Canadian Beaver (Castor canadensis) and North American Moose (Alces americanus).

PubMed

Wong, Mabel T; Wang, Weijun; Lacourt, Michael; Couturier, Marie; Edwards, Elizabeth A; Master, Emma R

2016-01-01

Strategic enrichment of microcosms derived from wood foragers can facilitate the discovery of key microbes that produce enzymes for the bioconversion of plant fiber (i.e., lignocellulose) into valuable chemicals and energy. In this study, lignocellulose-degrading microorganisms from the digestive systems of Canadian beaver (Castor canadensis) and North American moose (Alces americanus) were enriched under methanogenic conditions for over 3 years using various wood-derived substrates, including (i) cellulose (C), (ii) cellulose + lignosulphonate (CL), (iii) cellulose + tannic acid (CT), and (iv) poplar hydrolysate (PH). Substantial improvement in the conversion of amended organic substrates into biogas was observed in both beaver dropping and moose rumen enrichment cultures over the enrichment phases (up to 0.36-0.68 ml biogas/mg COD added), except for enrichments amended with tannic acid where conversion was approximately 0.15 ml biogas/mg COD added. Multiplex-pyrosequencing of 16S rRNA genes revealed systematic shifts in the population of Firmicutes, Bacteroidetes, Chlorobi, Spirochaetes, Chloroflexi, and Elusimicrobia in response to the enrichment. These shifts were predominantly substrate driven, not inoculum driven, as revealed by both UPGMA clustering pattern and OTU distribution. Additionally, the relative abundance of multiple OTUs from poorly defined taxonomic lineages increased from less than 1% to 25-50% in microcosms amended with lignocellulosic substrates, including OTUs from classes SJA-28, Endomicrobia, orders Bacteroidales, OPB54, and family Lachnospiraceae. This study provides the first direct comparison of shifts in microbial communities that occurred in different environmental samples in response to multiple relevant lignocellulosic carbon sources, and demonstrates the potential of enrichment to increase the abundance of key lignocellulolytic microorganisms and encoded activities.

Substrate-Driven Convergence of the Microbial Community in Lignocellulose-Amended Enrichments of Gut Microflora from the Canadian Beaver (Castor canadensis) and North American Moose (Alces americanus)

PubMed Central

Wong, Mabel T.; Wang, Weijun; Lacourt, Michael; Couturier, Marie; Edwards, Elizabeth A.; Master, Emma R.

2016-01-01

Strategic enrichment of microcosms derived from wood foragers can facilitate the discovery of key microbes that produce enzymes for the bioconversion of plant fiber (i.e., lignocellulose) into valuable chemicals and energy. In this study, lignocellulose-degrading microorganisms from the digestive systems of Canadian beaver (Castor canadensis) and North American moose (Alces americanus) were enriched under methanogenic conditions for over 3 years using various wood-derived substrates, including (i) cellulose (C), (ii) cellulose + lignosulphonate (CL), (iii) cellulose + tannic acid (CT), and (iv) poplar hydrolysate (PH). Substantial improvement in the conversion of amended organic substrates into biogas was observed in both beaver dropping and moose rumen enrichment cultures over the enrichment phases (up to 0.36–0.68 ml biogas/mg COD added), except for enrichments amended with tannic acid where conversion was approximately 0.15 ml biogas/mg COD added. Multiplex-pyrosequencing of 16S rRNA genes revealed systematic shifts in the population of Firmicutes, Bacteroidetes, Chlorobi, Spirochaetes, Chloroflexi, and Elusimicrobia in response to the enrichment. These shifts were predominantly substrate driven, not inoculum driven, as revealed by both UPGMA clustering pattern and OTU distribution. Additionally, the relative abundance of multiple OTUs from poorly defined taxonomic lineages increased from less than 1% to 25–50% in microcosms amended with lignocellulosic substrates, including OTUs from classes SJA-28, Endomicrobia, orders Bacteroidales, OPB54, and family Lachnospiraceae. This study provides the first direct comparison of shifts in microbial communities that occurred in different environmental samples in response to multiple relevant lignocellulosic carbon sources, and demonstrates the potential of enrichment to increase the abundance of key lignocellulolytic microorganisms and encoded activities. PMID:27446004

Severe Acute Respiratory Syndrome Coronavirus Replication Is Severely Impaired by MG132 due to Proteasome-Independent Inhibition of M-Calpain

PubMed Central

Schneider, Martha; Ackermann, Kerstin; Stuart, Melissa; Wex, Claudia; Protzer, Ulrike; Schätzl, Hermann M.

2012-01-01

The ubiquitin-proteasome system (UPS) is involved in the replication of a broad range of viruses. Since replication of the murine hepatitis virus (MHV) is impaired upon proteasomal inhibition, the relevance of the UPS for the replication of the severe acute respiratory syndrome coronavirus (SARS-CoV) was investigated in this study. We demonstrate that the proteasomal inhibitor MG132 strongly inhibits SARS-CoV replication by interfering with early steps of the viral life cycle. Surprisingly, other proteasomal inhibitors (e.g., lactacystin and bortezomib) only marginally affected viral replication, indicating that the effect of MG132 is independent of proteasomal impairment. Induction of autophagy by MG132 treatment was excluded from playing a role, and no changes in SARS-CoV titers were observed during infection of wild-type or autophagy-deficient ATG5−/− mouse embryonic fibroblasts overexpressing the human SARS-CoV receptor, angiotensin-converting enzyme 2 (ACE2). Since MG132 also inhibits the cysteine protease m-calpain, we addressed the role of calpains in the early SARS-CoV life cycle using calpain inhibitors III (MDL28170) and VI (SJA6017). In fact, m-calpain inhibition with MDL28170 resulted in an even more pronounced inhibition of SARS-CoV replication (>7 orders of magnitude) than did MG132. Additional m-calpain knockdown experiments confirmed the dependence of SARS-CoV replication on the activity of the cysteine protease m-calpain. Taken together, we provide strong experimental evidence that SARS-CoV has unique replication requirements which are independent of functional UPS or autophagy pathways compared to other coronaviruses. Additionally, this work highlights an important role for m-calpain during early steps of the SARS-CoV life cycle. PMID:22787216

Impaired protection against Trichinella spiralis in mice with high levels of IgE.

PubMed

Watanabe, Naohiro

2014-04-01

Helminth infection induces production of a large amount of immunoglobulin E (IgE) to nonhelminth antigens. Although such "irrelevant" IgE is a major proportion of total IgE in the host, its biological significance remains unclear. Therefore, I examined protective activity against Trichinella spiralis in mice with high levels of IgE by repeated injections of anti-dansyl IgE monoclonal antibody or Nippostrongylus brasiliensis infection. Injected anti-dansyl IgE occupied IgE receptors on mast cells in naive mice. Protective activity against T. spiralis, determined with number of muscle larvae 5weeks after infection, was impaired in mice treated with anti-dansyl IgE. The impaired protection was found in mice treated with anti-dansy IgE 7 and 14days after infection, but not 21 and 28days after infection, indicating that IgE-dependent protection operates at an early stage after infection. In the next experiments, mice were infected with N. brasiliensis 4weeks before T. spiralis infection to obtain high levels of IgE. The protective activity against T. spiralis was decreased by N. brasiliensis infection. On the other hand, protection against T. spiralis was comparable in IgE-deficient SJA/9 mice and in anti-IgE-treated BALB/c mice with or without N. brasiliensis infection, suggesting that impairment of protection is dependent on IgE. These results indicate that the high levels of irrelevant IgE are beneficial for helminths and, alternatively, that anti-helminth IgE antibodies are protective for hosts. In addition, the impaired protection was found in IgE high-responder mice but not in low-responder mice, suggesting that protection against T. spiralis is controlled by IgE responsiveness in the host. Copyright © 2013 Elsevier B.V. All rights reserved.

Identification and characterization of microRNAs in the pancreatic fluke Eurytrema pancreaticum.

PubMed

Xu, Min-Jun; Wang, Chun-Ren; Huang, Si-Yang; Fu, Jing-Hua; Zhou, Dong-Hui; Chang, Qiao-Cheng; Zheng, Xu; Zhu, Xing-Quan

2013-01-25

Eurytrema pancreaticum is one of the most common flukes, which mainly infects ruminants globally and infects human beings accidentally; causing eurytremiasis that has high veterinary and economic importance. MicroRNAs (miRNAs) are small non-coding RNAs and are now considered as a key mechanism of gene regulation at the post-transcription level. We investigated the global miRNA expression profile of E. pancreaticum adults using next-generation sequencing technology combined with real-time quantitative PCR. By using the genome of the closely-related species Schistosoma japonicum as reference, we obtained 27 miRNA candidates out of 16.45 million raw sequencing reads, with 13 of them found as known miRNAs in S. japonicum and/or S. mansoni, and the remaining 14 miRNAs were considered as novel. Five out of the 13 known miRNAs coming from one family named as sja-miR-2, including family members from miR-2a to miR-2e. Targets of 19 miRNAs were successfully predicated out of the 17401 mRNA and EST non-redundant sequences of S. japonicum. It was found that a significant high number of targets were related to "chch domain-containing protein mitochondrial precursor" (n = 29), "small subunit ribosomal protein s30e" (n = 21), and "insulin-induced gene 1 protein" (n = 9). Besides, "egg protein cp3842" (n = 2), "fumarate hydratase" (n = 2), "ubiquitin-conjugating enzyme" (n = 2), and "sperm-associated antigen 6" (n = 1) were also found as targets of the miRNAs of E. pancreaticum. The present study represents the first global characterization of E. pancreaticum miRNAs, which provides novel resources for a better understanding of the parasite, which, in turn, has implications for the effective control of the disease it causes.

Histochemical analysis of glycoconjugates in the skin of a catfish (arius tenuispinis, day).

PubMed

Al-Banaw, A; Kenngott, R; Al-Hassan, J M; Mehana, N; Sinowatz, F

2010-02-01

A histochemical study using conventional carbohydrate histochemistry (periodic-acid staining including diastase controls, alcian blue staining at pH 1 and 2.5) as well as using a battery of 14 fluorescein isothiocyanate (FITC)-labelled lectins to identify glycoconjugates present in 10 different areas of the skin of a catfish (Arius tenuispinis) was carried out. The lectins used were: mannose-binding lectins (Con A, LCA and PSA), galactose-binding lectins (PNA, RCA), N-acetylgalactosamine-binding lectins (DBA, SBA, SJA and GSL I), N-acetylglucosamine-binding lectins (WGA and WGAs), fucose-binding lectins (UEA) and lectins which bind to complex carbohydrate configurations (PHA E, PHA L). Conventional glycoconjugate staining (PAS staining, alcian blue at pH 1 and 2.5) showed that the mucous goblet cells contain a considerable amount of glycoconjugates in all locations of the skin, whereas the other unicellular gland type, the club cells, lacked these glycoconjugates. The glycoproteins found in goblet cells are neutral and therefore stain magenta when subjected to PAS staining. Alcian blue staining indicating acid glycoproteins was distinctly positive at pH 1, but gave only a comparable staining at pH 2.5. The mucus of the goblet cells therefore also contains acid glycoproteins rich in sulphate groups. Using FITC-labelled lectins, the carbohydrate composition of the glycoproteins of goblet cells could be more fully characterized. A distinct staining of the mucus of goblet cells was found with the mannose-binding lectins LCA and PSA; the galactosamine-binding lectins DBA, SBA and GLS I; the glucosamine-binding lectin WGA; and PHA E which stains glycoproteins with complex carbohydrate configurations. No reaction occurred with the fucose-binding lectin UEA and the sialic acid-specific lectin SNA. In addition, the galactose-binding lectins PNA and RCA showed only a weak or completely negative staining of the mucus in the goblet cells. The specificity of the lectin staining

P-Cable: New High-Resolution 3D Seismic Acquisition Technology

NASA Astrophysics Data System (ADS)

Planke, Sverre; Berndt, Christian; Mienert, Jürgen; Bünz, Stefan; Eriksen, Frode N.; Eriksen, Ola K.

2010-05-01

ø, VBPR, P-Cable 3D Seismic AS (P3S), and IFM-GEOMAR. Presently, a Norwegian national infrastructure consortium (Univ. of Tromsø, P3S, Univ. of Bergen, NGU) assembles a mobile P-Cable2 high-resolution 3D seismic system for fully operational use of the technology for scientific purposes.

Geo-Seas - building a unified e-infrastructure for marine geoscientific data management in Europe

NASA Astrophysics Data System (ADS)

Glaves, H.; Schaap, D.

2012-04-01

collaborative links with other European projects including EMODNET, Eurofleets. Genesi-DEC and iMarine as well as extending to the wider marine geoscientific and oceanographic community including projects in the USA such as the Rolling Deck Repository (R2R) initiative and also organisations in both the USA and Australia. On behalf of the Geo-Seas consortium partners: NERC-BGS (United Kingdom), NERC-BODC (United Kingdom), NERC-NOCS (United Kingdom), MARIS (Netherlands), IFREMER (France), BRGM (France), TNO (Netherlands), BSH (Germany), IGME (Spain), LNEG (Portugal), GSI (Ireland), BGR (Germany), OGS (Italy), GEUS (Denmark), NGU (Norway), PGI (Poland), EGK (Estonia), NRC-IGG (Lithuania), IO-BAS (Bulgaria), NOA (Greece), CIRIA (United Kingdom), MUMM (Belgium), UB (Spain), UCC (Ireland), EU-Consult (Netherlands), CNRS (France), SHOM (France), CEFAS (United Kingdom), and LU (Latvia).

Isotopic composition (oxygen and hydrogen) of groundwater in Norway - a review of current knowledge and future perspectives

NASA Astrophysics Data System (ADS)

Kracht, O.

2012-04-01

A review of current knowledge and available data covering the stable isotope composition of groundwater in Norway is presented. Furthermore, the future challenge of obtaining systematic background datasets and of integrating isotopes into the mainstream of hydrogeological observation programmes is discussed. I will summarize our experiences gained from different preliminary studies and will try to identify relationships to existing datasets, historical registrations, and networks on precipitation data. The study of transient effects in hydrological cycles is highly topical as these are supposed to provide means for investigating the effects of climate change and increasing human activities. From a hydrogeological point of view, is critical to establish suitable tools for the large scale observation of changes in groundwater recharge and depletion, their likely controls, and the expected nature of responses to changing climate, urbanization and other human activities. In this context, stable isotopes (δ18O and δ2H of water) can provide an expedient instrument to investigate the general hydrological setting, connections, and pathways of various scale aquifer systems. However, we are up to now missing an expedient background dataset on hydrogeological and hydrological stable isotopes observations for mainland Norway. Against this background, during years 2010 and 2011 the Geological Survey of Norway (NGU) organized two nation-wide sampling campaigns on the stable isotope composition of modern groundwater. These pilot studies aimed to obtain a first overview about the data ranges and natural variations to be expected. We used stations from the existing Norwegian Groundwater Monitoring Network (Landsomfattende Grunnvannsnett, LGN) to collect samples of groundwater at 55 different locations throughout Norway. As a main characteristic of these two datasets, all δ18O and δ2H values of the "LGN series" were well correlated and plotted close to the global meteoric water

Numerical investigation of the triggering mechanisms of the Piz Dora sackung system (Val Mustair, Switzerland)

NASA Astrophysics Data System (ADS)

Riva, Federico; Agliardi, Federico; Crosta, Giovanni B.; Zanchi, Andrea

2015-04-01

combinations of rock mass properties and persistent brittle structural patterns related to folding or regional stress fields. We analysed the processes leading to DSGSD onset and evolution by testing combinations of: a) rock mass constitutive models; b) in situ stress fields; c) hydro-mechanical coupling; d) dynamic loadings. DEM results, validated using field evidence and discussed against the results of continuum-based Finite-Element models (Agliardi et al., 2014; Barbarano et al., 2015), suggest that DSGSD failure mechanisms are constrained by fold-related brittle structures, and stress and hydrologic conditioning of deglaciation were key triggers modulated by active tectonic processes. References: - Agliardi F., Barbarano M., Crosta G.B., Riva F. & Zanchi A. (2014). Inherited and active tectonic controls on the Piz Dora sackung system (Val Mustair). In 3rd Slope Tectonic Conference proceedings, NGU Report 2014.030. - Barbarano M., Agliardi F., Crosta G. B., & Zanchi A. (2015). Inherited and Active Tectonic Controls on the Piz Dora DSGSD (Val Müstair, Switzerland). In Engineering Geology for Society and Territory-Volume 2 (pp. 605-608). Springer International Publishing.

Igneous and Ore-Forming Processes at the Roots of Giant - Ultra-Mafic Pluming System: the Seiland Igneous Comples, Norway

NASA Astrophysics Data System (ADS)

Larsen, R. B.; Iljina, M.; Schanke, M.

2012-12-01

SIP covers an area of 5500 km2 in N. Norway. 50 % of the volume comprises mafic layered or homogenous plg+px+Fe-Ti±ol gabbros. 25 % of the area comprises ultramafic intrusions, mostly peridotite and subsidiary pyroxenite and hornblendite. 25 % comprises calc-alkaline and alkaline plutons, respectively. Ultramafic plutons intersect gabbros and calc-alkaline plutons. Recent zircon U/Pb geochronology imply that SIP formed at 560-570 Ma, with mafic- and ultramafic rocks being emplaced in <4 Ma (Roberts et al., Geol. Mag, 2007). Geothermobarometry of contact metamorphic mineral assemblages, implies minimum depth of 20-30 kilometres. Accordingly, the Seiland province arguably provides a unique cross section through the deep-seated parts of a huge magmatic plumbing system. Sulphide Cu-Ni-(PGE) deposits are intimately associated with the ultramafic rock suite. One deposit from Stjernøy comprises sulphide dissiminations at the floor of a peridotitic pluton, another deposit occur at the floor of the Reinfjord ultramafic layered complex in the far West of SIP and the third deposit comprises vertical sulphide dykes in the interior of a hornblendite on the Øksfjord peninsula. Currently, only the Reinfjord deposit is studied in detail. The Reinfjord intrusions is layered and develops from olivine clinopyroxenites in the Lower Zone to wherlite in the Middle Zone to wehrlites and dunite in the Upper Zone. Earlier studies suggest parental melts with pyroxenitic compositions whereas the dunites and wherlites formed by fractional crystallization (Bennet et al., Bull. NGU, 405, 1-41). During our fieldwork we observed spectacular examples of cumulus structures, not previously reported, and including modally layered and modally graded dunite/wherlite, cross-bedding, slumping and mush-diapirs. Finally we saw an example of magma-replenishment where an olivine pyroxenitic magma was emplaced in to and mixed with the contemporary olivine/wherlite mushes!. The country rock gabbros were

Silurian and Devonian in Vietnam—Stratigraphy and facies

NASA Astrophysics Data System (ADS)

Thanh, Tống Duy; Phương, Tạ Hoàng; Janvier, Philippe; Hùng, Nguyễn Hữu; Cúc, Nguyễn Thị Thu; Dương, Nguyễn Thùy

2013-09-01

Silurian and Devonian deposits in Viet Nam are present in several zones and regions, including Quang Ninh, East Bac Bo, and West Bac Bo Zones of the Bac Bo Region, the Dien Bien-Nghe An and Binh Tri Thien Zones of the Viet-Lao Region, and the South Trung Bo, and Western Nam Bo Zones of the South Viet Nam Region (Fig. 1). The main lithological features and faunal composition of the Silurian and Devonian Units in all these zones are briefly described. The Silurian consists of deep-water deposits of the upper parts of the Co To and Tan Mai Formations in the Quang Ninh Zone, the upper parts of the Phu Ngu Formation in the East Bac Bo Zone and the upper parts of the Long Dai and Song Ca Formations in the Viet-Lao Region. Shallow water facies Silurian units containing benthic faunas are more widely distributed, including the upper part of the Sinh Vinh and Bo Hieng Formations in the West Bac Bo Zone, the Kien An Formation in the Quang Ninh Zone, and, in the Viet-Lao Region, the Dai Giang Formation and the upper part of the Tay Trang Formation. No Lower and Middle Devonian deposits indicate deep water facies, but they are characterized by different shallow water facies. Continental to near shore, deltaic facies characterize the Lower Devonian Song Cau Group in the East Bac Bo Zone, the Van Canh Formation in the Quang Ninh Zone, and the A Choc Formation in the Binh Tri Thien Zone. Similar facies also occur in the Givetian Do Son Formation of the Quang Ninh Zone, and the Tan Lap Formation in the East Bac Bo Zone, and consist of coarse terrigenous deposits—cross-bedded conglomerates, sandstone, etc. Most Devonian units are characterized by shallow marine shelf facies. Carbonate and terrigenous-carbonate facies dominate, and terrigenous facies occur in the Lower and Middle Devonian sections in some areas only. The deep-water-like facies is characteriztic for some Upper Devonian formations in the Bac Bo (Bang Ca and Toc Tat Formations) and Viet-Lao Regions (Thien Nhan and

Trans people's experiences with assisted reproduction services: a qualitative study.

PubMed

James-Abra, S; Tarasoff, L A; Green, D; Epstein, R; Anderson, S; Marvel, S; Steele, L S; Ross, L E

2015-06-01

assisting trans people to become parents through the use of AR, our study demonstrates that they are already accessing or attempting to access these services. This reality necessitates a shift toward exploring the ways in which AR services can be improved to better meet the needs of this population, from the perspectives of both service users and service providers. This project was supported by the Canadian Institutes of Health Research-Institute of Gender and Health, in partnership with the Assisted Human Reproduction Canada: Catalyst Grant: Psychosocial Issues Associated with Assisted Human Reproduction (FRN-103595). S.M. was supported by a Canada Graduate Scholarship from the Social Science and Humanities Research Council, as well as research funding from Osgoode Hall Law School, York University. S.J.-A. was supported by an Ontario Graduate Scholarship funded by the Province of Ontario and the University of Toronto. N/A. © The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Ethical questions in landslide management and risk reduction in Norway

NASA Astrophysics Data System (ADS)

Taurisano, A.; Lyche, E.; Thakur, V.; Wiig, T.; Øvrelid, K.; Devoli, G.

2012-04-01

The loss of lives caused by landslides in Norway is smaller than in other countries due to the low population density in exposed areas. However, annual economic losses from damage to properties and infrastructures are vast. Yet nationally coordinated efforts to manage and reduce landslide and snow avalanche risk are a recent challenge, having started only in the last decade. Since 2009, this has been a task of the Norwegian Water Resources and Energy Directorate (NVE) under the Ministry of Petroleum and Energy. Ongoing work includes collection of landslide data, production of susceptibility and hazard maps, planning of mitigation measures along with monitoring and early warning systems, assistance to areal planning, providing expertise in emergencies and disseminating information to the public. These activities are realized in collaboration with the Norwegian Geological Survey (NGU), the Meteorological Institute, the Road and Railway authorities, universities and private consultant companies. As the total need for risk mitigating initiatives is by far larger than the annual budget, priority assessment is crucial. This brings about a number of ethical questions. 1. Susceptibility maps have been produced for the whole country and provide a first indication of areas with potential landslide or snow avalanche hazard, i.e. areas where special attention and expert assessments are needed before development. Areas where no potential hazard is shown can in practice be developed without further studies, which call for relatively conservative susceptibility maps. However, conservative maps are problematic as they too often increase both cost and duration of building projects beyond the reasonable. 2. Areas where hazard maps or risk mitigation initiatives will be funded are chosen by means of cost-benefits analyses which are often uncertain. How to estimate the benefits if the real probability for damage can only be judged on a very subjective level but not really calculated

Variations in Pb concentrations and Pb-isotope ratios in soils collected along an east-west transect across the United States

NASA Astrophysics Data System (ADS)

Smith, David; Woodruff, Laurel; Reimann, Clemens; Flem, Belinda

2014-05-01

Soil A-horizon and C-horizon samples were collected along a 4000 km long transect cutting the USA from the west to the east coast. For purposes of site selection, the transect was divided into approximately 40-km segments. For each segment, a 1-km2 target area was selected at random. Soil A- and C-horizon samples were collected at a site within each target area that was most representative of the surrounding landscape. The samples were air-dried at ambient temperature, disaggregated, and sieved through a 2-mm stainless steel screen. The <2-mm material was crushed to <150 µm in a ceramic mill prior to chemical analysis. Lead was analyzed in all the A- and C-horizon samples by inductively coupled plasma-mass spectrometry following a 4-acid digestion. The complete dataset can be found in Smith et al., 2005. Pb-isotope ratio measurements were carried out on 159 soil A-horizon and 137 soil C-horizon samples on an inductively coupled sector field plasma mass spectrometer (SF-ICP-MS; ELEMENT 1, Finnigan MAT) in the laboratory of the Geological Survey of Norway (NGU), following a 7 N HNO3 digestion. Lead concentrations along the transect show (1) generally higher values in the soil A-horizon than the C-horizon (median 21 vs. 16.5 mg/kg), (2) an increase in the median value of the soil A-horizon for the central to eastern U.S. (Missouri to Maryland) when compared to the western U.S. (California to Kansas) (median 26 vs. 20 mg/kg) and (3) a higher A/C ratio for the central to eastern US (1.35 vs. 1.14). Lead isotopes show a distinct trend across the U.S., with the highest 206Pb/207Pb ratios occurring in the centre (Missouri, median A-horizon: 1.245; C-horizon: 1.251) and the lowest at both coasts (e.g. California, median A-horizon: 1.195; C-horizon:1.216). The soil C-horizon samples show generally higher 206Pb/207Pb ratios than the A-horizon (median C-horizon: 1.224; A-horizon: 1.219). The 206Pb/207Pb isotope ratios in the soil A horizon show a correlation with the total

Web-GIS approach for integrated analysis of heterogeneous georeferenced data

NASA Astrophysics Data System (ADS)

Okladnikov, Igor; Gordov, Evgeny; Titov, Alexander; Shulgina, Tamara

2014-05-01

atmospheric composition and climate (MACC) Collaborated Project, NOAA-CIRES Twentieth Century Global Reanalysis Version II, NCEP Climate Forecast System Reanalysis (CFSR), meteorological observational data for the territory of the former USSR for the 20th century, results of modeling by global and regional climatological models, and others are available for processing by the system. The Web-GIS information-computational system for heterogeneous geophysical data analysis provides specialists involved into multidisciplinary research projects with reliable and practical instruments for integrated research of climate and ecosystems changes on global and regional scales. With its help even an unskilled in programming user is able to process and visualize multidimensional observational and model data through unified web-interface using a common graphical web-browser. This work is partially supported by SB RAS project VIII.80.2.1, RFBR grant #13-05-12034, grant #14-05-00502, and integrated project SB RAS #131. References 1. Gordov E.P., Lykosov V.N., Krupchatnikov V.N., Okladnikov I.G., Titov A.G., Shulgina T.M. Computational and information technologies for monitoring and modeling of climate changes and their consequences. - Novosibirsk: Nauka, Siberian branch, 2013. - 195 p. (in Russian) 2. Felice Frankel, Rosalind Reid. Big data: Distilling meaning from data // Nature. Vol. 455. N. 7209. P. 30. 3. T.M. Shulgina, E.P. Gordov, I.G. Okladnikov, A.G., Titov, E.Yu. Genina, N.P. Gorbatenko, I.V. Kuzhevskaya, A.S. Akhmetshina. Software complex for a regional climate change analysis. // Vestnik NGU. Series: Information technologies. 2013. Vol. 11. Issue 1. P. 124-131 (in Russian). 4. I.G. Okladnikov, A.G. Titov, T.M. Shulgina, E.P. Gordov, V.Yu. Bogomolov, Yu.V. Martynova, S.P. Suschenko, A.V. Skvortsov. Software for analysis and visualization of climate change monitoring and forecasting data // Numerical methods and programming, 2013. Vol. 14. P. 123-131 (in Russian).

Development of virtual research environment for regional climatic and ecological studies and continuous education support

NASA Astrophysics Data System (ADS)

Gordov, Evgeny; Lykosov, Vasily; Krupchatnikov, Vladimir; Bogomolov, Vasily; Gordova, Yulia; Martynova, Yulia; Okladnikov, Igor; Titov, Alexander; Shulgina, Tamara

2014-05-01

measurements data and support profound statistical analysis of storaged and modeled on demand data. In particular, one can run the integrated models, preprocess modeling results data, using dedicated modules for numerical processing perform analysys and visualize obtained results. New functionality recently has been added to the statistical analysis tools set aimed at detailed studies of climatic extremes occurring in Northern Asia. The VRE element is also supporting thematic educational courses for students and post-graduate students of the Tomsk State University. In particular, it allow students to perform on-line thematic laboratory work cycles on the basics of analysis of current and potential future regional climate change using Siberia territory as an example (Gordova et al, 2013). We plan to expand the integrated models set and add comprehensive surface and Arctic Ocean description. Developed VRE element "Climate" provides specialists involved into multidisciplinary research projects with reliable and practical instruments for integrated research of climate and ecosystems changes on global and regional scales. With its help even a user without programming skills can process and visualize multidimensional observational and model data through unified web-interface using a common graphical web-browser. This work is partially supported by SB RAS project VIII.80.2.1, RFBR grant 13-05-12034, grant 14-05-00502, and integrated project SB RAS 131. References 1. Gordov E.P., Lykosov V.N., Krupchatnikov V.N., Okladnikov I.G., Titov A.G., Shulgina T.M. Computationaland information technologies for monitoring and modeling of climate changes and their consequences. Novosibirsk: Nauka, Siberian branch, 2013. - 195 p. (in Russian) 2. T.M. Shulgina, E.P. Gordov, I.G. Okladnikov, A.G., Titov, E.Yu. Genina, N.P. Gorbatenko, I.V. Kuzhevskaya,A.S. Akhmetshina. Software complex for a regional climate change analysis. // Vestnik NGU. Series: Information technologies. 2013. Vol. 11. Issue 1. P

Consequence assessment of large rock slope failures in Norway

NASA Astrophysics Data System (ADS)

Oppikofer, Thierry; Hermanns, Reginald L.; Horton, Pascal; Sandøy, Gro; Roberts, Nicholas J.; Jaboyedoff, Michel; Böhme, Martina; Yugsi Molina, Freddy X.

2014-05-01

Steep glacially carved valleys and fjords in Norway are prone to many landslide types, including large rockslides, rockfalls, and debris flows. Large rockslides and their secondary effects (rockslide-triggered displacement waves, inundation behind landslide dams and outburst floods from failure of landslide dams) pose a significant hazard to the population living in the valleys and along the fjords shoreline. The Geological Survey of Norway performs systematic mapping of unstable rock slopes in Norway and has detected more than 230 unstable slopes with significant postglacial deformation. This large number necessitates prioritisation of follow-up activities, such as more detailed investigations, periodic displacement measurements, continuous monitoring and early-warning systems. Prioritisation is achieved through a hazard and risk classification system, which has been developed by a panel of international and Norwegian experts (www.ngu.no/en-gb/hm/Publications/Reports/2012/2012-029). The risk classification system combines a qualitative hazard assessment with a consequences assessment focusing on potential life losses. The hazard assessment is based on a series of nine geomorphological, engineering geological and structural criteria, as well as displacement rates, past events and other signs of activity. We present a method for consequence assessment comprising four main steps: 1. computation of the volume of the unstable rock slope; 2. run-out assessment based on the volume-dependent angle of reach (Fahrböschung) or detailed numerical run-out modelling; 3. assessment of possible displacement wave propagation and run-up based on empirical relations or modelling in 2D or 3D; and 4. estimation of the number of persons exposed to rock avalanches or displacement waves. Volume computation of an unstable rock slope is based on the sloping local base level technique, which uses a digital elevation model to create a second-order curved surface between the mapped extent of

Geo-Seas - a pan-European infrastructure for the management of marine geological and geophysical data.

NASA Astrophysics Data System (ADS)

Glaves, Helen; Graham, Colin

2010-05-01

countries. This makes the direct use of primary data in an integrated way very difficult and also hampers use of the data sets in a harmonised way to produce multidisciplinary data products and services. To ensure interoperability with other marine environmental data types Geo-Seas ISO19115 metadata, OGC and GeoSciML standards will be used as the basis for the metadata profiles for the geological and geophysical data. This will be largely achieved by modifying the SeaDataNet metadata standard profile (Common Data Index or CDI), which is itself based upon the ISO19115 standard, to accommodate the requirements of the Geo-Seas project. The overall objective of Geo-Seas project is to build and deploy a unified marine geoscientific data infrastructure within Europe which will in effect provide a data grid for the sharing of marine geological and geophysical data. This will result in a major improvement in the locating, accessing and delivery of federated marine geological and geophysical data and data products from national geological surveys and research institutes across Europe. There is an emphasis on interoperability both with other disciplines as well as with other key framework projects including the European Marine Observation and Data Network (EMODNet) and One Geology - Europe. In addition, a key objective of the Geo-Seas project is to underpin European directives such as INSPIRE as well as recent framework programmes on both the global and European scale, for example Global Earth Observation System of Systems (GEOSS) and Global Monitoring for Environment and Security (GMES), all of which are intended to encourage the exchange of data and information. Geo-Seas consortium partners: NERC-BGS (United Kingdom), NERC-BODC (United Kingdom), NERC-NOCS (United Kingdom), MARIS (Netherlands), IFREMER (France), BRGM (France), TNO (Netherlands), BSH (Germany), IGME (Spain), INETI (Portugal), IGME (Greece), GSI (Ireland), BGR (Germany), OGS (Italy), GEUS (Denmark), NGU (Norway), PGI

If Your Child Learns in Two Languages: A Parent's Guide for Improving Educational Opportunities for Children Acquiring English as a Second Language = Si su nino aprende en dos idiomes: Una guia para que las familias sepan como mejorar las oportunidades educativas de los ninos que adquieren el ingles como segunda lengua = Neu lon Ban Hoc Bang Hai Thu Tieng: Chi-nam cua phu-huynh de cai tien co hoi hoc van cua con em dang hoc Anh van nhu sinh ngu thu hai.

ERIC Educational Resources Information Center

Zelasko, Nancy; Antunez, Beth

This guide, in English, Spanish, and Vietnamese, aims to inform parents of students who have learned or are learning English as a Second Language about appropriate approaches for educating children so that they can work with schools to ensure a high quality education for their children. The emphasis is on explaining the laws, schools, and research…