LOOKING WEST, BETWEEN READING DEPOT BRIDGE AND SKEW ARCH BRIDGE ...
LOOKING WEST, BETWEEN READING DEPOT BRIDGE AND SKEW ARCH BRIDGE (HAER No. PA-116). - Philadelphia & Reading Railroad, Reading Depot Bridge, North Sixth Street at Woodward Street, Reading, Berks County, PA
Assessment of seismic performance of skew reinforced concrete box girder bridges
NASA Astrophysics Data System (ADS)
Abdel-Mohti, Ahmed; Pekcan, Gokhan
2013-12-01
The seismic vulnerability of highway bridges remains an important problem and has received increased attention as a consequence of unprecedented damage observed during several major earthquakes. A significant number of research studies have examined the performance of skew bridges under service and seismic loads. The results of these studies are particularly sensitive to modeling assumptions in view of the interacting parameters. In the present study, three-dimensional improved beam-stick models of two-span highway bridges with skew angles varying from 0° to 60° are developed to investigate the seismic response characteristics of skew box girder bridges. The relative accuracy of beam-stick models is verified against counterpart finite element models. The effect of various parameters and conditions on the overall seismic response was examined such as skew angle, ground motion intensity, soil condition, abutment support conditions, bridge aspect ratio, and foundation-base conditions. The study shows that the improved beam-stick models can be used to conduct accurate nonlinear time history analysis of skew bridges. Skew angle and interacting parameters were found to have significant effect on the behavior of skewed highway bridges. Furthermore, the performance of shear keys may have a predominant effect on the overall seismic response of the skew bridges.
Evaluating the performance of skewed prestressed concrete bridge after strengthening
NASA Astrophysics Data System (ADS)
Naser, Ali Fadhil; Zonglin, Wang
2013-06-01
The objectives of this paper are to explain the application of repairing and strengthening methods on the damaged members of the bridge structure, to analyze the static and dynamic structural response under static and dynamic loads after strengthening, and to evaluate the structural performance after application of strengthening method. The repairing and strengthening methods which are used in this study include treatment of the cracks, thickening the web of box girder along the bridge length and adding internal pre-stressing tendons in the thickening web, and construct reinforced concrete cross beams (diaphragms) between two box girders. The results of theoretical analysis of static and dynamic structural responses after strengthening show that the tensile stresses are decreased and become less than the allowable limit values in the codes. The values of vertical deflection are decreased after strengthening. The values of natural frequencies after strengthening are increased, indicating that the strengthening method is effective to reduce the vibration of the bridge structure. Therefore, the strengthening methods are effective to improve the bearing capacity and elastic working state of the bridge structure and to increase the service life of the bridge structure.
Truck loading positions for maximum live load girder moment in skewed integral bridges
NASA Astrophysics Data System (ADS)
Yalcin, O. Fatih
2015-12-01
In this study, the effect of the longitudinal and transverse truck positions on the distribution of live load moment among the girders of skewed integral abutment bridges (SIBs) is investigated. For this purpose, three dimensional finite element models (FEMs) of several single-span SIBs are built and analyzed. In the analyses, bridges with various skew angles under all possible single and double truck loading positions both in longitudinal and transverse directions are considered. An automated analysis procedure managed by a visual basic program is developed to obtain the structural models and apply the wheel loads of trucks. The finite element analyses (FEA) results are then used to find the most critical loading cases of single truck and adjacent two trucks for the live load moment in the girders of SIBs. The results revealed that, the trucks should be placed nearby the midline of the bridge deck in a diagonal manner.
Construction engineering of steel tub-girder bridge systems for skew effects
NASA Astrophysics Data System (ADS)
Jimenez Chong, Juan Manuel
Closed structural sections, such as those having circular, rectangular or trapezoidal shape, possess high rotational rigidity when compared to open sections such as I-girders. The high torsional rigidity of closed sections makes them ideal for use in highly curved bridges. In this case, the geometry of the bridge results in large torsional forces. Because of structural efficiency and economy reasons, most of these closed-section bridges consist of a trapezoidal cross-section, with a top concrete slab and bottom and side steel plates. The slab is cast after the steel is erected and thus a system of internal diaphragms and braces is necessary to stabilize the system during erection. During the steel erection and the early stages of the concrete deck placement, the section can be considered as quasi-closed as the top concrete flange has not been cast or is not yet effective. During steel erection, undetermined and/or large torsional forces and/or displacements may result in fit-up problems requiring large stresses to overcome. During concrete deck placement, the undetermined displacements can affect the control of the deck thickness and the final deck geometry, such as the alignment of deck joints and the matching of stages in phased constructions projects. Due to the interactions between their various components, the behavior of curved and skewed tub-girder bridges is significantly more complex than that of straight bridges. When skewed supports are used in tub-girders, the interaction of the girder bending rotations and the displacement constraints induced by the skewed support diaphragms causes twisting of the girders at the supports. These twist rotations introduce additional torques into the system. Both curvature and skew can cause design and construction difficulties, especially at the supports, where the corresponding steel dead load deflections and the large torsional stiffness of the girders may lead to large fit-up forces. Currently, the general
Peggs, S.; Dell, G.F.
1994-12-31
The on-momentum description of linear coupling between horizontal and vertical betatron motion is extended to include off-momentum particles, introducing a vector quantity called the ``skew chromaticity``. This vector tends to be long in large superconducting storage rings, where it restricts the available working space in the tune plane, and modifies collective effect stability criteria. Skew chromaticity measurements at the Cornell Electron Storage Ring (CESR) and at the Fermilab Tevatron are reported, as well as tracking results from the Relativistic Heavy Ion Collider (RHIC). The observation of anomalous head-tail beam Iowa new the tune diagonal in the Tevatron are explained in terms of the extended theory, including modified criteria for headtail stability. These results are confirmed in head-tail simulations. Sources of skew chromaticity are investigated.
4. North portal of Skew Span looking south and leading ...
4. North portal of Skew Span looking south and leading to Span 1 Main Bridge on the left and Span 1 Hot Metal Bridge on the right. - Monongahela Connecting Railroad Company, Main Bridge, Spanning Monongahela River at mile post 3.1, Pittsburgh, Allegheny County, PA
2. Skew Span on left to Span 3 on right ...
2. Skew Span on left to Span 3 on right from north bank-up river. - Monongahela Connecting Railroad Company, Hot Metal Bridge, Spanning Monongahela River at mile post 3.1, Pittsburgh, Allegheny County, PA
4. From Skew Span to portal on span 1 looking ...
4. From Skew Span to portal on span 1 looking up grade toward the south end. - Monongahela Connecting Railroad Company, Hot Metal Bridge, Spanning Monongahela River at mile post 3.1, Pittsburgh, Allegheny County, PA
3. Span 4 on right to Skew Span on leftfrom ...
3. Span 4 on right to Skew Span on left-from south bank-up river. - Monongahela Connecting Railroad Company, Hot Metal Bridge, Spanning Monongahela River at mile post 3.1, Pittsburgh, Allegheny County, PA
Audenaert, Koenraad M. R.
2014-11-15
In this paper, we study the quantum generalisation of the skew divergence, which is a dissimilarity measure between distributions introduced by Lee in the context of natural language processing. We provide an in-depth study of the quantum skew divergence, including its relation to other state distinguishability measures. Finally, we present a number of important applications: new continuity inequalities for the quantum Jensen-Shannon divergence and the Holevo information, and a new and short proof of Bravyi's Small Incremental Mixing conjecture.
12. Underside of Skew SpanHot Metal system on right, toward ...
12. Underside of Skew Span-Hot Metal system on right, toward Rocker Bent. - Monongahela Connecting Railroad Company, Hot Metal Bridge, Spanning Monongahela River at mile post 3.1, Pittsburgh, Allegheny County, PA
Skew resisting hydrodynamic seal
Conroy, William T.; Dietle, Lannie L.; Gobeli, Jeffrey D.; Kalsi, Manmohan S.
2001-01-01
A novel hydrodynamically lubricated compression type rotary seal that is suitable for lubricant retention and environmental exclusion. Particularly, the seal geometry ensures constraint of a hydrodynamic seal in a manner preventing skew-induced wear and provides adequate room within the seal gland to accommodate thermal expansion. The seal accommodates large as-manufactured variations in the coefficient of thermal expansion of the sealing material, provides a relatively stiff integral spring effect to minimize pressure-induced shuttling of the seal within the gland, and also maintains interfacial contact pressure within the dynamic sealing interface in an optimum range for efficient hydrodynamic lubrication and environment exclusion. The seal geometry also provides for complete support about the circumference of the seal to receive environmental pressure, as compared the interrupted character of seal support set forth in U.S. Pat. Nos. 5,873,576 and 6,036,192 and provides a hydrodynamic seal which is suitable for use with non-Newtonian lubricants.
Detecting skewness from summary information.
Altman, D G; Bland, J M
1996-11-01
Many statistical methods of analysis assume that the data have a normal distribution. When the data do not, they can often be changed to make them more normal. However, readers of published papers may wish to be certain that the authors have conducted a proper analysis. One can clearly see whether the distributional assumption is met when data are presented in the form of a histogram or scatter diagram. However, when only summary statistics are presented, the task becomes far more difficult. An idea of the distribution can be gleaned if the summary statistics include the range of the data. For example, a range from 7 to 41 around a mean of 15 suggests that the data are positively skewed. Belief in that assumption may be unreliable because the range is based upon the two most extreme, and atypical, values. Similar asymmetry affecting the lower and upper quartiles would better indicate a skewed distribution. it is suggested that for measurements which must be positive, if the mean is smaller than twice the standard deviation, the data are likely to be skewed. A second indicator of skewness can be used when there are data for several groups of individuals. Deviations from the normal distribution and a relation between the standard deviation and mean across groups often go together. A standard deviation which increases as the mean increases is a strong indication of positively skewed data, and specifically that a log transformation may be needed.
Skew chromaticity in large accelerators
Peggs, S.; Dell, G.F.
1995-05-01
The 2-D ``skew chromaticity`` vector k is introduced when the standard on-momentum description of linear coupling is extended to include off-momentum particles. A lattice that is well decoupled on-momentum may be badly decoupled off-momentum, inside the natural momentum spread of the beam. There are two general areas of concern: (1) the free space in the tune plane is decreased; (2) collective phenomena may be destabilized. Two strong new criteria for head-tail stability in the presence of off-momentum coupling are derived, which are consistent with experimental and operational observations at the Tevatron, and with tracking data from RHIC.
Kinematic correction for roller skewing
NASA Technical Reports Server (NTRS)
Savage, M.; Loewenthal, S. H.
1980-01-01
A theory of kinematic stabilization of rolling cylinders is developed for high-speed cylindrical roller bearings. This stabilization requires race and roller crowning to product changes in the rolling geometry as the roller shifts axially. These changes put a reverse skew in the rolling elements by changing the rolling taper. Twelve basic possible bearing modifications are identified in this paper. Four have single transverse convex curvature in the rollers while eight have rollers with compound transverse curvature composed of a central cylindrical band of constant radius surrounded by symmetric bands with both slope and transverse curvature.
Mixture of Skewed α-Stable Distributions
NASA Astrophysics Data System (ADS)
Shojaei, S. R. Hosseini; Nassiri, V.; Mohammadian, Gh. R.; Mohammadpour, A.
2011-03-01
Expectation maximization (EM) algorithm and the Bayesian techniques are two approaches for statistical inference of mixture models [3, 4]. By noting the advantages of the Bayesian methods, practitioners prefer them. However, implementing Markov chain Monte Carlo algorithms can be very complicated for stable distributions, due to the non-analytic density or distribution function formulas. In this paper, we introduce a new class of mixture of heavy-tailed distributions, called mixture of skewed stable distributions. Skewed stable distributions belongs to the exponential family and they have analytic density representation. It is shown that skewed stable distributions dominate skew stable distribution functions and they can be used to model heavy-tailed data. The class of skewed stable distributions has an analytic representation for its density function and the Bayesian inference can be done similar to the exponential family of distributions. Finally, mixture of skewed stable distributions are compared to the mixture of stable distributions through a simulations study.
Roller skewing measurements in cylindrical roller bearings
NASA Technical Reports Server (NTRS)
Nypan, L. J.
1981-01-01
Measurements of roller skewing in a 118 mm bore roller bearing operating at shaft speeds to 12,000 rpm are reported. High speed motion pictures of a modified roller were taken through a derotation prism to record skewing as the roller moved through loaded and unloaded regions of the bearing. Subsequent frame by frame measurement of the photographic film provided information on roller skewing. Radial and tangential skew amplitudes of 0.4 to 0.5 degrees were observed with 0.5 degree misalignment.
Modeling skewness in human transcriptomes.
Casellas, Joaquim; Varona, Luis
2012-01-01
Gene expression data are influenced by multiple biological and technological factors leading to a wide range of dispersion scenarios, although skewed patterns are not commonly addressed in microarray analyses. In this study, the distribution pattern of several human transcriptomes has been studied on free-access microarray gene expression data. Our results showed that, even in previously normalized gene expression data, probe and differential expression within probe effects suffer from substantial departures from the commonly assumed symmetric gaussian distribution. We developed a flexible mixed model for non-competitive microarray data analysis that accounted for asymmetric and heavy-tailed (Student's t distribution) dispersion processes. Random effects for gene expression data were modeled under asymmetric Student's t distributions where the asymmetry parameter (λ) took values from perfect symmetry (λ = 0) to right- (λ>0) or left-side (λ>0) over-expression patterns. This approach was applied to four free-access human data sets and revealed clearly better model performance when comparing with standard approaches accounting for traditional symmetric gaussian distribution patterns. Our analyses on human gene expression data revealed a substantial degree of right-hand asymmetry for probe effects, whereas differential gene expression addressed both symmetric and left-hand asymmetric patterns. Although these results cannot be extrapolated to all microarray experiments, they highlighted the incidence of skew dispersion patterns in human transcriptome; moreover, we provided a new analytical approach to appropriately address this biological phenomenon. The source code of the program accommodating these analytical developments and additional information about practical aspects on running the program are freely available by request to the corresponding author of this article. PMID:22701729
Portfolio optimization with skewness and kurtosis
NASA Astrophysics Data System (ADS)
Lam, Weng Hoe; Jaaman, Saiful Hafizah Hj.; Isa, Zaidi
2013-04-01
Mean and variance of return distributions are two important parameters of the mean-variance model in portfolio optimization. However, the mean-variance model will become inadequate if the returns of assets are not normally distributed. Therefore, higher moments such as skewness and kurtosis cannot be ignored. Risk averse investors prefer portfolios with high skewness and low kurtosis so that the probability of getting negative rates of return will be reduced. The objective of this study is to compare the portfolio compositions as well as performances between the mean-variance model and mean-variance-skewness-kurtosis model by using the polynomial goal programming approach. The results show that the incorporation of skewness and kurtosis will change the optimal portfolio compositions. The mean-variance-skewness-kurtosis model outperforms the mean-variance model because the mean-variance-skewness-kurtosis model takes skewness and kurtosis into consideration. Therefore, the mean-variance-skewness-kurtosis model is more appropriate for the investors of Malaysia in portfolio optimization.
Agrawal, Prateek; Chacko, Zackaria; Fortes, Elaine C. F. S.; Kilic, Can
2016-05-10
We explore a novel flavor structure in the interactions of dark matter with the Standard Model. We consider theories in which both the dark matter candidate, and the particles that mediate its interactions with the Standard Model fields, carry flavor quantum numbers. The interactions are skewed in flavor space, so that a dark matter particle does not directly couple to the Standard Model matter fields of the same flavor, but only to the other two flavors. This framework respects minimal flavor violation and is, therefore, naturally consistent with flavor constraints. We study the phenomenology of a benchmark model in whichmore » dark matter couples to right-handed charged leptons. In large regions of parameter space, the dark matter can emerge as a thermal relic, while remaining consistent with the constraints from direct and indirect detection. The collider signatures of this scenario include events with multiple leptons and missing energy. In conclusion, these events exhibit a characteristic flavor pattern that may allow this class of models to be distinguished from other theories of dark matter.« less
Reproductive skew in the polygynandrous acorn woodpecker.
Haydock, Joseph; Koenig, Walter D
2002-05-14
Reproductive skew models, which focus on the degree to which reproduction is shared equally (low skew) or monopolized by a single individual (high skew) within groups, have been heralded as providing a general unifying framework for understanding the factors determining social evolution. Here, we test the ability of optimal skew, or "transactional," models, which predict the level of skew necessary to promote stable associations of dominants and subordinates, rather than independent breeding, to predict reproductive partitioning in the acorn woodpecker (Melanerpes formicivorus). This species provides a key test case because only a few vertebrates exhibit polygynandry (multiple breeders of both sexes within a group). Contrary to the predictions of the models, joint-nesting females share reproduction more equitably than expected, apparently because egg destruction and the inability of females to defend their eggs from cobreeders eliminate any possibility for one female to control reproduction. For males, however, reproductive skew is high, with the most successful male siring over three times as many young as the next most successful male. Although this result is consistent with optimal skew models, other aspects of male behavior are not; in particular, the reproductively most successful male frequently switches between nests produced by the same set of cobreeders, and we were unable to detect any phenotypic correlate of success. These results are consistent with an alternative null model in which cobreeder males have equal chance of paternity, but paternity of offspring within broods is nonindependent as a consequence of female, rather than male, control.
SKEW QUADRUPOLE FOCUSING LATTICES AND APPLICATIONS.
PARKER,B.
2001-06-18
In this paper we revisit using skew quadrupole fields in place of traditional normal upright quadrupole fields to make beam focusing structures. We illustrate by example skew lattice decoupling, dispersion suppression and chromatic correction using the neutrino factory Study-II muon storage ring design. Ongoing BNL investigation of flat coil magnet structures that allow building a very compact muon storage ring arc and other flat coil configurations that might bring significant magnet cost reduction to a VLHC motivate our study of skew focusing.
Tunable skewed edges in puckered structures
NASA Astrophysics Data System (ADS)
Grujić, Marko M.; Ezawa, Motohiko; Tadić, Milan Ž.; Peeters, François M.
2016-06-01
We propose a type of edges arising due to the anisotropy inherent in the puckered structure of a honeycomb system such as in phosphorene. Skewed-zigzag and skewed-armchair nanoribbons are semiconducting and metallic, respectively, in contrast to their normal edge counterparts. Their band structures are tunable, and a metal-insulator transition is induced by an electric field. We predict a field-effect transistor based on the edge states in skewed-armchair nanoribbons, where the edge state is gapped by applying arbitrary small electric field Ez. A topological argument is presented, revealing the condition for the emergence of such edge states.
Women's Memory Advantage Might Skew Alzheimer's Diagnosis
... https://medlineplus.gov/news/fullstory_161328.html Women's Memory Advantage Might Skew Alzheimer's Diagnosis Women tend to hold on to better verbal memory skills as they age compared to men, study ...
Skew estimation of document images using bagging.
Meng, Gaofeng; Pan, Chunhong; Zheng, Nanning; Sun, Chen
2010-07-01
This paper proposes a general-purpose method for estimating the skew angles of document images. Rather than to derive a skew angle merely from text lines, the proposed method exploits various types of visual cues of image skew available in local image regions. The visual cues are extracted by Radon transform and then outliers of them are iteratively rejected through a floating cascade. A bagging (bootstrap aggregating) estimator is finally employed to combine the estimations on the local image blocks. Our experimental results show significant improvements against the state-of-the-art methods, in terms of execution speed and estimation accuracy, as well as the robustness to short and sparse text lines, multiple different skews and the presence of nontextual objects of various types and quantities.
High reproductive skew in tropical hover wasps.
Sumner, Seirian; Casiraghi, Maurizio; Foster, William; Field, Jeremy
2002-01-22
A plethora of recent models examines how genetic and environmental factors might influence partitioning of reproduction ('skew') in animal societies, but empirical data are sparse. We used three microsatellite loci to estimate skew on 13 nests of the Malaysian hover wasp, Liostenogaster flavolineata. Groups are small in L. flavolineata (1-10 females) and all females are capable of mating and laying eggs. Despite considerable variation between nests in parameters expected to influence skew, skew was uniformly high. On 11 of the 13 nests, all female eggs had been laid by a single dominant female. A second female had laid one to two out of 5-10 eggs respectively on the two remaining nests. A likelihood analysis suggested that on average, 90% of the male eggs had also been laid by the dominant. The slightly lower skew among male eggs might reflect the lower average relatedness of subordinates to male versus female offspring of the dominant. We suggest that high skew in L. flavolineata may result from strong ecological constraints and a relatively high probability that a subordinate will eventually inherit the dominant, egg-laying position.
Static ocular counterroll reflex in skew deviation
Chandrakumar, M.; Blakeman, A.; Goltz, H.C.; Sharpe, J.A.
2011-01-01
Objective: The static ocular counterroll (OCR) reflex generates partially compensatory torsional eye movements during head roll. It is mediated by the utricle in the inner ear. Skew deviation is a vertical strabismus thought to be caused by imbalance in the utriculo-ocular pathway. We hypothesized that if skew deviation is indeed caused by damage to this reflex pathway, patients with skew deviation would show abnormal OCR. Methods: Eighteen patients with skew deviation caused by brainstem or cerebellar lesions and 18 normal participants viewed a target at 1 m. Ocular responses to static passive head roll-tilts of approximately 20° were recorded using search coils. Static OCR gain was calculated as the change in torsional eye position divided by the change in head position during sustained head roll. Perception of the subjective visual vertical (SVV) was also measured. Results: Group mean OCR gain was reduced by 45% in patients. At an individual level, OCR gains were asymmetric between eyes and between torsional directions in 90% of patients. In addition, the hypotropic eye incyclotorting gain was lower than the hypertropic eye excyclotorting gain during head roll toward the hypotropic eye in 94% of patients. No consistent pattern of gain asymmetry was found during head roll toward the hypertropic eye. The SVV was tilted toward the hypotropic eye. Conclusion: Static OCR gain is significantly reduced in skew deviation. Interocular and directional gain asymmetries are also prevalent. The asymmetries provide further evidence that disruption of the utriculo-ocular pathway is a mechanism for skew deviation. PMID:21813791
Skewness and Kurtosis in Statistical Kinetics
NASA Astrophysics Data System (ADS)
Barato, Andre C.; Seifert, Udo
2015-10-01
We obtain lower and upper bounds on the skewness and kurtosis associated with the cycle completion time of unicyclic enzymatic reaction schemes. Analogous to a well-known lower bound on the randomness parameter, the lower bounds on skewness and kurtosis are related to the number of intermediate states in the underlying chemical reaction network. Our results demonstrate that evaluating these higher order moments with single molecule data can lead to information about the enzymatic scheme that is not contained in the randomness parameter.
Skew chicane based betatron eigenmode exchange module
Douglas, David
2010-12-28
A skewed chicane eigenmode exchange module (SCEEM) that combines in a single beamline segment the separate functionalities of a skew quad eigenmode exchange module and a magnetic chicane. This module allows the exchange of independent betatron eigenmodes, alters electron beam orbit geometry, and provides longitudinal parameter control with dispersion management in a single beamline segment with stable betatron behavior. It thus reduces the spatial requirements for multiple beam dynamic functions, reduces required component counts and thus reduces costs, and allows the use of more compact accelerator configurations than prior art design methods.
HOT METAL BRIDGE (NOTE: BUILDERS: JONES AND LAUGHLIN STEEL CA. ...
HOT METAL BRIDGE (NOTE: BUILDERS: JONES AND LAUGHLIN STEEL CA. 1890), SOUTH PORTAL. THREE PIN CONNECTED CAMELBACK TRUSS SPANS, ONE SKEWED THROUGH TRUSS SPAN ON NORTH SIDE TRUSS BRIDGE, EAST OF HOT METAL BRIDGE BUILT BY AMERICAN BRIDGE COMPANY CA. 1910. (RIVETED MULTI-SPAN TRUSS). - Jones & Laughlin Steel Corporation, Pittsburgh Works, Morgan Billet Mill Engine, 550 feet north of East Carson Street, opposite South Twenty-seventh Street, Pittsburgh, Allegheny County, PA
Optimal Weak-Lensing Skewness Measurements
NASA Astrophysics Data System (ADS)
Zhang, Tong-Jie; Pen, Ue-Li; Zhang, Pengjie; Dubinski, John
2003-12-01
Weak-lensing measurements are starting to provide statistical maps of the distribution of matter in the universe that are increasingly precise and complementary to cosmic microwave background maps. The most common measurement is the correlation in alignments of background galaxies, which can be used to infer the variance of the projected surface density of matter. This measurement of the fluctuations is insensitive to the total mass content and is analogous to using waves on the ocean to measure its depths. However, when the depth is shallow, as happens near a beach, waves become skewed. Similarly, a measurement of skewness in the projected matter distribution directly measures the total matter content of the universe. While skewness has already been convincingly detected, its constraint on cosmology is still weak. We address optimal analyses for the Canada-France-Hawaii Telescope Legacy Survey in the presence of noise. We show that a compensated Gaussian filter with a width of 2.5‧ optimizes the cosmological constraint, yielding ΔΩm/Ωm~10%. This is significantly better than other filters that have been considered in the literature. This can be further improved with tomography and other sophisticated analyses.
Generalized skew coefficients for flood-frequency analysis in Minnesota
Lorenz, D.L.
1997-01-01
This report presents an evaluation of generalized skew coefficients used in flood-frequency analysis. Station skew coefficients were computed for 267 long-term stream-gaging stations in Minnesota and the surrounding states of Iowa, North and South Dakota, Wisconsin, and the provinces of Manitoba and Ontario, Canada. Generalized skew coefficients were computed from station skew coefficients using a locally weighted regression technique. The resulting regression trend surface was the generalized skew coefficient map, except for the North Shore area, and has a mean square error of 0.182.
Dynamic Modeling from Flight Data with Unknown Time Skews
NASA Technical Reports Server (NTRS)
Morelli, Eugene A.
2016-01-01
A method for estimating dynamic model parameters from flight data with unknown time skews is described and demonstrated. The method combines data reconstruction, nonlinear optimization, and equation-error parameter estimation in the frequency domain to accurately estimate both dynamic model parameters and the relative time skews in the data. Data from a nonlinear F-16 aircraft simulation with realistic noise, instrumentation errors, and arbitrary time skews were used to demonstrate the approach. The approach was further evaluated using flight data from a subscale jet transport aircraft, where the measured data were known to have relative time skews. Comparison of modeling results obtained from time-skewed and time-synchronized data showed that the method accurately estimates both dynamic model parameters and relative time skew parameters from flight data with unknown time skews.
Inferring climate variability from skewed proxy records
NASA Astrophysics Data System (ADS)
Emile-Geay, J.; Tingley, M.
2013-12-01
Many paleoclimate analyses assume a linear relationship between the proxy and the target climate variable, and that both the climate quantity and the errors follow normal distributions. An ever-increasing number of proxy records, however, are better modeled using distributions that are heavy-tailed, skewed, or otherwise non-normal, on account of the proxies reflecting non-normally distributed climate variables, or having non-linear relationships with a normally distributed climate variable. The analysis of such proxies requires a different set of tools, and this work serves as a cautionary tale on the danger of making conclusions about the underlying climate from applications of classic statistical procedures to heavily skewed proxy records. Inspired by runoff proxies, we consider an idealized proxy characterized by a nonlinear, thresholded relationship with climate, and describe three approaches to using such a record to infer past climate: (i) applying standard methods commonly used in the paleoclimate literature, without considering the non-linearities inherent to the proxy record; (ii) applying a power transform prior to using these standard methods; (iii) constructing a Bayesian model to invert the mechanistic relationship between the climate and the proxy. We find that neglecting the skewness in the proxy leads to erroneous conclusions and often exaggerates changes in climate variability between different time intervals. In contrast, an explicit treatment of the skewness, using either power transforms or a Bayesian inversion of the mechanistic model for the proxy, yields significantly better estimates of past climate variations. We apply these insights in two paleoclimate settings: (1) a classical sedimentary record from Laguna Pallcacocha, Ecuador (Moy et al., 2002). Our results agree with the qualitative aspects of previous analyses of this record, but quantitative departures are evident and hold implications for how such records are interpreted, and
Graf, Darin C.; Warpinski, Norman R.
1996-01-01
A system for single-phase, steady-state permeability measurements of porous rock utilizes a fluid bridge arrangement analogous to a Wheatstone bridge. The arms of the bridge contain the sample and calibrated flow resistors.
GC skew and mitochondrial origins of replication.
Sahyoun, Abdullah H; Bernt, Matthias; Stadler, Peter F; Tout, Kifah
2014-07-01
The comprehensive understanding of mitochondrial genome evolution requires a detailed mechanistic picture of mitogenomic replication. Despite many previous efforts it has remained a non-trivial problem to determine the origins of replication and trace their fate across rearrangements of the gene order even in the small genomes of animal mitochondria. We elaborate here on the observation that the GC skew is correlated with the distance from the replication origins. This effect has been explained as a consequence of the standard model of mitochondrial DNA replication, i.e. the strand displacement model. According to this model chemical damage accumulates proportional to the duration that DNA is exposed in single-stranded form during replication (Dssh) which depends on the relative position with respect to the replication origins. Based on this model we developed a computational method to infer the positions of both the heavy strand and the light strand origin from nucleotide skew data. In a comprehensive survey of deuterostome mitochondria we infer conserved replication origins for the vast majority of vertebrates and cephalochordates. Deviations from the consensus picture are presumably associated with genome rearrangements.
Temperature-Compensated Clock Skew Adjustment
Castillo-Secilla, Jose María; Palomares, Jose Manuel; Olivares, Joaquín
2013-01-01
This work analyzes several drift compensation mechanisms in wireless sensor networks (WSN). Temperature is an environmental factor that greatly affects oscillators shipped in every WSN mote. This behavior creates the need of improving drift compensation mechanisms in synchronization protocols. Using the Flooding Time Synchronization Protocol (FTSP), this work demonstrates that crystal oscillators are affected by temperature variations. Thus, the influence of temperature provokes a low performance of FTSP in changing conditions of temperature. This article proposes an innovative correction factor that minimizes the impact of temperature in the clock skew. By means of this factor, two new mechanisms are proposed in this paper: the Adjusted Temperature (AT) and the Advanced Adjusted Temperature (A2T). These mechanisms have been combined with FTSP to produce AT-FTSP and A2T-FTSP Both have been tested in a network of TelosB motes running TinyOS. Results show that both AT-FTSP and A2T-FTSP improve the average synchronization errors compared to FTSP and other temperature-compensated protocols (Environment-Aware Clock Skew Estimation and Synchronization for WSN (EACS) and Temperature Compensated Time Synchronization (TCTS)). PMID:23966192
Evolution and models for skewed parton distribution
Musatov, I.C.; Radyushkin, A.V.
1999-05-17
The authors discuss the structure of the ''forward visible'' (FW) parts of double and skewed distributions related to usual distributions through reduction relations. They use factorized models for double distributions (DDs) {tilde f}(x,{alpha}) in which one factor coincides with the usual (forward) parton distribution and another specifies the profile characterizing the spread of the longitudinal momentum transfer. The model DDs are used to construct skewed parton distributions (SPDs). For small skewedness, the FW parts of SPDs H ({tilde x},{xi}) can be obtained by averaging forward parton densities f({tilde x}-{xi}{alpha}) with the weight {rho}({alpha}) coinciding with the profile function of the double distribution {tilde f}(x, {alpha}) at small x. They show that if the x{sup n} moments {tilde f}{sub n}({alpha}) of DDs have the asymptotic (1-{alpha}{sup 2}){sup n+1} profile, then the {alpha}-profile of {tilde f}(x,{alpha}) for small x is completely determined by small-x behavior of the usual parton distribution. They demonstrate that, for small {xi}, the model with asymptotic profiles for {tilde f}{sub n}({alpha}) is equivalent to that proposed recently by Shuvaev et al., in which the Gegenbauer moments of SPDs do not depend on {xi}. They perform a numerical investigation of the evolution patterns of SPDs and give interpretation of the results of these studies within the formalism of double distributions.
Coefficient of variation calculated from the range for skewed distributions.
Rhiel, G Steven
2006-02-01
In this research a coefficient of variation (CVS(high.low)) is developed that is calculated from the highest and lowest values in a set of data for samples from skewed distributions. A correction factor is determined such that CVS(high-low) is a dose estimate of the population coefficient of variation when sampling from three skewed chi-squared distributions and three skewed empirical distributions. The empirical distributions are from "real-world" data sets in psychology and education.
Analysis of skew plate problems with various constraints
NASA Astrophysics Data System (ADS)
Mizusawa, T.; Kajita, T.; Naruoka, M.
1980-12-01
This paper presents the application of the modified Rayleigh-Ritz method with Lagrange multipliers to analyze skew plate problems with various constraints. By this procedure one can satisfy both geometric and natural boundary conditions of skew plates. To demonstrate the accuracy and versatility of the method, several examples of bending, vibration and buckling of skew plates are solved, and results are compared with those obtained by other approximate methods.
Robust skew estimation using straight lines in document images
NASA Astrophysics Data System (ADS)
Koo, Hyung Il; Cho, Nam Ik
2016-05-01
A skew-estimation method using straight lines in document images is presented. Unlike conventional approaches exploiting the properties of text, we formulate the skew-estimation problem as an estimation task using straight lines in images and focus on robust and accurate line detection. To be precise, we adopt a block-based edge detector followed by a progressive line detector to take clues from a variety of sources such as text lines, boundaries of figures/tables, vertical/horizontal separators, and boundaries of textblocks. Extensive experiments on the datasets of skewed images and competition results reveal that the proposed method works robustly and yields accurate skew-estimation results.
Three Bridge Fryer's Ford Bridge, Nimrod Bridge, and Ward's ...
Three Bridge - Fryer's Ford Bridge, Nimrod Bridge, and Ward's Crossing Bridge - Fryer's Ford Bridge, Spanning East Fork of Point Remove Creek at Fryer Bridge Road (CR 67), Solgohachia, Conway County, AR
Cracked shells under skew-symmetric loading
NASA Technical Reports Server (NTRS)
Lelale, F.
1982-01-01
A shell containing a through crack in one of the principal planes of curvature and under general skew-symmetric loading is considered. By employing a Reissner type shell theory which takes into account the effect of transverse shear strains, all boundary conditions on the crack surfaces are satisfied separately. Consequently, unlike those obtained from the classical shell theory, the angular distributions of the stress components around the crack tips are shown to be identical to the distributions obtained from the plane and antiplane elasticity solutions. Extensive results are given for axially and circumferentially cracked cylindrical shells, spherical shells, and toroidal shells under uniform inplane shearing, out of plane shearing, and torsion. The effect of orthotropy on the results is also studied.
Incorporating covariates in skewed functional data models.
Li, Meng; Staicu, Ana-Maria; Bondell, Howard D
2015-07-01
We introduce a class of covariate-adjusted skewed functional models (cSFM) designed for functional data exhibiting location-dependent marginal distributions. We propose a semi-parametric copula model for the pointwise marginal distributions, which are allowed to depend on covariates, and the functional dependence, which is assumed covariate invariant. The proposed cSFM framework provides a unifying platform for pointwise quantile estimation and trajectory prediction. We consider a computationally feasible procedure that handles densely as well as sparsely observed functional data. The methods are examined numerically using simulations and is applied to a new tractography study of multiple sclerosis. Furthermore, the methodology is implemented in the R package cSFM, which is publicly available on CRAN.
Accounting for Skewness in Ensemble Data Assimilation
NASA Astrophysics Data System (ADS)
Hodyss, D.
2011-12-01
I will discuss a new framework for understanding how a non-normal probability density function (pdf) may affect a state estimate and how one might usefully exploit the non-normal properties of the pdf when constructing a state estimate. A Bayesian framework is constructed that leads naturally to an expansion of the expected forecast error in a polynomial series consisting of powers of the innovation vector. This polynomial expansion in the innovation reveals a new view of the geometric nature of the state estimation problem. Among other things a direct relationship is shown between the degree to which the state estimate varies with the innovation and the moments of the distribution. A practical data assimilation algorithm will also be presented that explicitly accounts for skewness in the prior distribution. The algorithm operates as a global-solve using a conjugate-gradient technique and Schur/Hadamard (element-wise) localization, and as a general rule is only a factor of four more expensive than the traditional ensemble Kalman filter. The central feature of this technique is the squaring of the innovation and the ensemble perturbations so as to create an extended state-space that accounts for the second, third and fourth moments of the prior distribution. This new technique is illustrated in a simple scalar system as well as in a Boussinesq model of O(10000) variables configured to simulate nonlinearly evolving Kelvin-Helmholtz waves in shear flow. It is shown that ensemble sizes of at least 100 members is needed to adequately resolve the third and fourth moments required for the algorithm. For ensembles of this size it is shown that this new technique is superior to a state-of-the-art Ensemble Kalman Filter in situations with significant skewness, otherwise the new algorithm reduces to the performance of the Ensemble Kalman Filter.
Evolution and models for skewed parton distributions
Musatov, I. V.; Radyushkin, A. V.
2000-04-01
We discuss the structure of the ''forward visible'' (FV) parts of double and skewed distributions related to the usual distributions through reduction relations. We use factorized models for double distributions (DD's) f(tilde sign)(x,{alpha}) in which one factor coincides with the usual (forward) parton distribution and another specifies the profile characterizing the spread of the longitudinal momentum transfer. The model DD's are used to construct skewed parton distributions (SPD's). For small skewedness, the FV parts of SPD's H(x(tilde sign),{xi}) can be obtained by averaging forward parton densities f(x(tilde sign)-{xi}{alpha}) with the weight {rho}({alpha}) coinciding with the profile function of the double distribution f(tilde sign)(x,{alpha}) at small x. We show that if the x{sup n} moments f(tilde sign){sub n}({alpha}) of DD's have the asymptotic (1-{alpha}{sup 2}){sup n+1} profile, then the {alpha} profile of f(tilde sign)(x,{alpha}) for small x is completely determined by the small-x behavior of the usual parton distribution. We demonstrate that, for small {xi}, the model with asymptotic profiles for f(tilde sign){sub n}({alpha}) is equivalent to that proposed recently by Shuvaev et al., in which the Gegenbauer moments of SPD's do not depend on {xi}. We perform a numerical investigation of the evolution patterns of SPD's and give an interpretation of the results of these studies within the formalism of double distributions. (c) 2000 The American Physical Society.
Learning a Novel Pattern through Balanced and Skewed Input
ERIC Educational Resources Information Center
McDonough, Kim; Trofimovich, Pavel
2013-01-01
This study compared the effectiveness of balanced and skewed input at facilitating the acquisition of the transitive construction in Esperanto, characterized by the accusative suffix "-n" and variable word order (SVO, OVS). Thai university students (N = 98) listened to 24 sentences under skewed (one noun with high token frequency) or…
A Method for Controlling Skew on Linked Surfaces
BENZLEY,STEVEN E.; KERR,ROBERT A.; MITCHELL,SCOTT A.; WHITE,DAVID R.
1999-09-27
A new method for lessening skew in mapped meshes is presented. This new method involves progressive subdivision of a surface into loops consisting of four sides. Using these loops, constraints can then be set on the curves of the surface, which will propagate interval assignments across the surface, allowing a mesh with a better skew metric to be generated.
Analysis of carbon dioxide concentration skewness at a rural site.
Pérez, Isidro A; Sánchez, M Luisa; García, M Ángeles; Ozores, Marta; Pardo, Nuria
2014-04-01
This paper provides evidence that symmetry of CO2 concentration distribution may indicate sources or dispersive processes. Skewness was calculated by different procedures with CO2 measured at a rural site using a Picarro G1301 analyser over a two-year period. The usual skewness coefficient was considered together with fourteen robust estimators. A noticeable contrast was obtained between day and night, and skewness decreased linearly with the logarithm of the height. One coefficient was selected from its satisfactory relationship with the median concentration in daily evolution. Three analyses based on the kernel smoothing method were conducted with this coefficient to investigate its response to yearly and daily evolutions, wind direction, and wind speed. Left-skewed distributions were linked to thermal turbulence during midday, especially in spring-summer, or with high wind speeds. Almost symmetric distributions were associated with sources, such as the Valladolid City plume reinforced with spring emissions and the lack of emissions in summer in the remaining directions. Finally, right-skewed distributions were related to low wind speeds and stable stratification at night, furthered by strong emissions in spring. Skewness intervals were proposed and their average median concentrations were calculated such that the relationship between skewness and concentration depends on the analysis performed. Since some skewness coefficients may also be negative, they provide better information about sources or dispersive processes than concentration.
ERIC Educational Resources Information Center
Tabor, Josh
2010-01-01
On the 2009 AP[c] Statistics Exam, students were asked to create a statistic to measure skewness in a distribution. This paper explores several of the most popular student responses and evaluates which statistic performs best when sampling from various skewed populations. (Contains 8 figures, 3 tables, and 4 footnotes.)
Female reproductive synchrony predicts skewed paternity across primates
Nunn, Charles L.; Schülke, Oliver
2008-01-01
Recent studies have uncovered remarkable variation in paternity within primate groups. To date, however, we lack a general understanding of the factors that drive variation in paternity skew among primate groups and across species. Our study focused on hypotheses from reproductive skew theory involving limited control and the use of paternity “concessions” by investigating how paternity covaries with the number of males, female estrous synchrony, and rates of extragroup paternity. In multivariate and phylogenetically controlled analyses of data from 27 studies on 19 species, we found strong support for a limited control skew model, with reproductive skew within groups declining as female reproductive synchrony and the number of males per group increase. Of these 2 variables, female reproductive synchrony explained more of the variation in paternity distributions. To test whether dominant males provide incentives to subordinates to resist matings by extragroup males, that is, whether dominants make concessions of paternity, we derived a novel prediction that skew is lower within groups when threat from outside the group exists. This prediction was not supported as a primary factor underlying patterns of reproductive skew among primate species. However, our approach revealed that if concessions occur in primates, they are most likely when female synchrony is low, as these conditions provide alpha male control of paternity that is assumed by concessions models. Collectively, our analyses demonstrate that aspects of male reproductive competition are the primary drivers of reproductive skew in primates. PMID:19018288
Utility functions predict variance and skewness risk preferences in monkeys.
Genest, Wilfried; Stauffer, William R; Schultz, Wolfram
2016-07-26
Utility is the fundamental variable thought to underlie economic choices. In particular, utility functions are believed to reflect preferences toward risk, a key decision variable in many real-life situations. To assess the validity of utility representations, it is therefore important to examine risk preferences. In turn, this approach requires formal definitions of risk. A standard approach is to focus on the variance of reward distributions (variance-risk). In this study, we also examined a form of risk related to the skewness of reward distributions (skewness-risk). Thus, we tested the extent to which empirically derived utility functions predicted preferences for variance-risk and skewness-risk in macaques. The expected utilities calculated for various symmetrical and skewed gambles served to define formally the direction of stochastic dominance between gambles. In direct choices, the animals' preferences followed both second-order (variance) and third-order (skewness) stochastic dominance. Specifically, for gambles with different variance but identical expected values (EVs), the monkeys preferred high-variance gambles at low EVs and low-variance gambles at high EVs; in gambles with different skewness but identical EVs and variances, the animals preferred positively over symmetrical and negatively skewed gambles in a strongly transitive fashion. Thus, the utility functions predicted the animals' preferences for variance-risk and skewness-risk. Using these well-defined forms of risk, this study shows that monkeys' choices conform to the internal reward valuations suggested by their utility functions. This result implies a representation of utility in monkeys that accounts for both variance-risk and skewness-risk preferences. PMID:27402743
Utility functions predict variance and skewness risk preferences in monkeys
Genest, Wilfried; Stauffer, William R.; Schultz, Wolfram
2016-01-01
Utility is the fundamental variable thought to underlie economic choices. In particular, utility functions are believed to reflect preferences toward risk, a key decision variable in many real-life situations. To assess the validity of utility representations, it is therefore important to examine risk preferences. In turn, this approach requires formal definitions of risk. A standard approach is to focus on the variance of reward distributions (variance-risk). In this study, we also examined a form of risk related to the skewness of reward distributions (skewness-risk). Thus, we tested the extent to which empirically derived utility functions predicted preferences for variance-risk and skewness-risk in macaques. The expected utilities calculated for various symmetrical and skewed gambles served to define formally the direction of stochastic dominance between gambles. In direct choices, the animals’ preferences followed both second-order (variance) and third-order (skewness) stochastic dominance. Specifically, for gambles with different variance but identical expected values (EVs), the monkeys preferred high-variance gambles at low EVs and low-variance gambles at high EVs; in gambles with different skewness but identical EVs and variances, the animals preferred positively over symmetrical and negatively skewed gambles in a strongly transitive fashion. Thus, the utility functions predicted the animals’ preferences for variance-risk and skewness-risk. Using these well-defined forms of risk, this study shows that monkeys’ choices conform to the internal reward valuations suggested by their utility functions. This result implies a representation of utility in monkeys that accounts for both variance-risk and skewness-risk preferences. PMID:27402743
Utility functions predict variance and skewness risk preferences in monkeys.
Genest, Wilfried; Stauffer, William R; Schultz, Wolfram
2016-07-26
Utility is the fundamental variable thought to underlie economic choices. In particular, utility functions are believed to reflect preferences toward risk, a key decision variable in many real-life situations. To assess the validity of utility representations, it is therefore important to examine risk preferences. In turn, this approach requires formal definitions of risk. A standard approach is to focus on the variance of reward distributions (variance-risk). In this study, we also examined a form of risk related to the skewness of reward distributions (skewness-risk). Thus, we tested the extent to which empirically derived utility functions predicted preferences for variance-risk and skewness-risk in macaques. The expected utilities calculated for various symmetrical and skewed gambles served to define formally the direction of stochastic dominance between gambles. In direct choices, the animals' preferences followed both second-order (variance) and third-order (skewness) stochastic dominance. Specifically, for gambles with different variance but identical expected values (EVs), the monkeys preferred high-variance gambles at low EVs and low-variance gambles at high EVs; in gambles with different skewness but identical EVs and variances, the animals preferred positively over symmetrical and negatively skewed gambles in a strongly transitive fashion. Thus, the utility functions predicted the animals' preferences for variance-risk and skewness-risk. Using these well-defined forms of risk, this study shows that monkeys' choices conform to the internal reward valuations suggested by their utility functions. This result implies a representation of utility in monkeys that accounts for both variance-risk and skewness-risk preferences.
Graf, D.C.; Warpinski, N.R.
1996-08-13
A system is described for single-phase, steady-state permeability measurements of porous rock which utilizes a fluid bridge arrangement analogous to a Wheatstone bridge. The arms of the bridge contain the sample and calibrated flow resistors. 8 figs.
Spin Hall Effects Due to Phonon Skew Scattering
NASA Astrophysics Data System (ADS)
Gorini, Cosimo; Eckern, Ulrich; Raimondi, Roberto
2015-08-01
A diversity of spin Hall effects in metallic systems is known to rely on Mott skew scattering. In this work its high-temperature counterpart, phonon skew scattering, which is expected to be of foremost experimental relevance, is investigated. In particular, the phonon skew scattering spin Hall conductivity is found to be practically T independent for temperatures above the Debye temperature TD. As a consequence, in Rashba-like systems a high-T linear behavior of the spin Hall angle demonstrates the dominance of extrinsic spin-orbit scattering only if the intrinsic spin splitting is smaller than the temperature.
PRINCIPLE OF SKEW QUADRUPOLE MODULATION TO MEASURE BETATRON COUPLING.
LUO.Y.PILAT,F.ROSER,T.ET AL.
2004-07-05
The measurement of the residual betatron coupling via skew quadrupole modulation is a new diagnostics technique that has been developed and tested at the Relativistic Heavy Ion Collider (RHIC) as a very promising method for the linear decoupling on the ramp. By modulating the strengths of different skew quadrupole families the two eigentunes are precisely measured with the phase lock loop system. The projections of the residual coupling coefficient onto the skew quadrupole coupling modulation directions are determined. The residual linear coupling could be corrected according to the measurement. An analytical solution for skew quadrupole modulation based on Hamiltonian perturbation approximation is given, and simulation code using smooth accelerator model is also developed. Some issues concerning the practical applications of this technique are discussed.
Systems of Differential Equations with Skew-Symmetric, Orthogonal Matrices
ERIC Educational Resources Information Center
Glaister, P.
2008-01-01
The solution of a system of linear, inhomogeneous differential equations is discussed. The particular class considered is where the coefficient matrix is skew-symmetric and orthogonal, and where the forcing terms are sinusoidal. More general matrices are also considered.
7. William E. Barrett, Photographer, 1974. SKEWED VIEW SHOWING CHEAT ...
7. William E. Barrett, Photographer, 1974. SKEWED VIEW SHOWING CHEAT RIVER VALLEY, REMAINS OF 1887 PIER AND c. 1900 MASONRY ARCHES. - Baltimore & Ohio Railroad, Tray Run Viaduct, Spanning Tray Run, Rowlesburg, Preston County, WV
Vibration of skewed cantilever plates and helicoidal shells
NASA Technical Reports Server (NTRS)
Beres, D. P.; Bailey, C. D.
1975-01-01
Theoretical vibration frequencies and mode shapes are obtained for skewed plates and helicoidal shells with a cantilever boundary. Using Hamilton's law of varying action, a power series solution is developed to obtain converged numerical results for the five lowest frequencies. Effects of geometrical variables such as aspect ratio, sweep angle and shell radius to thickness ratio are investigated. Accuracy of the solution method is substantiated by comparison with existing skewed plate spherical cap, and conical shell results.
NASA Astrophysics Data System (ADS)
Xiaoshi, Zhu; Chixiao, Chen; Jialiang, Xu; Fan, Ye; Junyan, Ren
2013-03-01
A sampling switch with an embedded digital-to-skew converter (DSC) is presented. The proposed switch eliminates time-interleaved ADCs' skews by adjusting the boosted voltage. A similar bridged capacitors' charge sharing structure is used to minimize the area. The circuit is fabricated in a 0.18 μm CMOS process and achieves sub-1 ps resolution and 200 ps timing range at a rate of 100 MS/s. The power consumption is 430 μW at maximum. The measurement result also includes a 2-channel 14-bit 100 MS/s time-interleaved ADCs (TI-ADCs) with the proposed DSC switch's demonstration. This scheme is widely applicable for the clock skew and aperture error calibration demanded in TI-ADCs and SHA-less ADCs.
Flow in Rotating Serpentine Coolant Passages With Skewed Trip Strips
NASA Technical Reports Server (NTRS)
Tse, David G.N.; Steuber, Gary
1996-01-01
Laser velocimetry was utilized to map the velocity field in serpentine turbine blade cooling passages with skewed trip strips. The measurements were obtained at Reynolds and Rotation numbers of 25,000 and 0.24 to assess the influence of trips, passage curvature and Coriolis force on the flow field. The interaction of the secondary flows induced by skewed trips with the passage rotation produces a swirling vortex and a corner recirculation zone. With trips skewed at +45 deg, the secondary flows remain unaltered as the cross-flow proceeds from the passage to the turn. However, the flow characteristics at these locations differ when trips are skewed at -45 deg. Changes in the flow structure are expected to augment heat transfer, in agreement with the heat transfer measurements of Johnson, et al. The present results show that trips are skewed at -45 deg in the outward flow passage and trips are skewed at +45 deg in the inward flow passage maximize heat transfer. Details of the present measurements were related to the heat transfer measurements of Johnson, et al. to relate fluid flow and heat transfer measurements.
Yuan, Shi-Min
2016-01-01
Myocardial bridging is rare. Myocardial bridges are most commonly localized in the middle segment of the left anterior descending coronary artery. The anatomic features of the bridges vary significantly. Alterations of the endothelial morphology and the vasoactive agents impact on the progression of atherosclerosis of myocardial bridging. Patients may present with chest pain, myocardial infarction, arrhythmia and even sudden death. Patients who respond poorly to the medical treatment with β-blockers warrant a surgical intervention. Myotomy is a preferred surgical procedure for the symptomatic patients. Coronary stent deployment has been in limited use due to the unsatisfactory long-term results. PMID:27074276
Sample skewness as a statistical measurement of neuronal tuning sharpness.
Samonds, Jason M; Potetz, Brian R; Lee, Tai Sing
2014-05-01
We propose using the statistical measurement of the sample skewness of the distribution of mean firing rates of a tuning curve to quantify sharpness of tuning. For some features, like binocular disparity, tuning curves are best described by relatively complex and sometimes diverse functions, making it difficult to quantify sharpness with a single function and parameter. Skewness provides a robust nonparametric measure of tuning curve sharpness that is invariant with respect to the mean and variance of the tuning curve and is straightforward to apply to a wide range of tuning, including simple orientation tuning curves and complex object tuning curves that often cannot even be described parametrically. Because skewness does not depend on a specific model or function of tuning, it is especially appealing to cases of sharpening where recurrent interactions among neurons produce sharper tuning curves that deviate in a complex manner from the feedforward function of tuning. Since tuning curves for all neurons are not typically well described by a single parametric function, this model independence additionally allows skewness to be applied to all recorded neurons, maximizing the statistical power of a set of data. We also compare skewness with other nonparametric measures of tuning curve sharpness and selectivity. Compared to these other nonparametric measures tested, skewness is best used for capturing the sharpness of multimodal tuning curves defined by narrow peaks (maximum) and broad valleys (minima). Finally, we provide a more formal definition of sharpness using a shape-based information gain measure and derive and show that skewness is correlated with this definition.
Quantum Fisher and skew information for Unruh accelerated Dirac qubit
NASA Astrophysics Data System (ADS)
Banerjee, Subhashish; Alok, Ashutosh Kumar; Omkar, S.
2016-08-01
We develop a Bloch vector representation of the Unruh channel for a Dirac field mode. This is used to provide a unified, analytical treatment of quantum Fisher and skew information for a qubit subjected to the Unruh channel, both in its pure form as well as in the presence of experimentally relevant external noise channels. The time evolution of Fisher and skew information is studied along with the impact of external environment parameters such as temperature and squeezing. The external noises are modelled by both purely dephasing phase damping and the squeezed generalised amplitude damping channels. An interesting interplay between the external reservoir temperature and squeezing on the Fisher and skew information is observed, in particular, for the action of the squeezed generalised amplitude damping channel. It is seen that for some regimes, squeezing can enhance the quantum information against the deteriorating influence of the ambient environment. Similar features are also observed for the analogous study of skew information, highlighting a similar origin of the Fisher and skew information.
NASA Technical Reports Server (NTRS)
1977-01-01
Safer bridges are among a number of spinoff benefits from NASA procedures for testing 'cfracture toughness" of a structural part, meaning its ability to -siscracktsh at might cause failure. The New River Bridge in West Virginia, shown under construction, is the world's largest single span bridge. U.S. Steel fracture toughness requirements for such bridges include NASA-developed test procedures. Bridge materials and other metal structures may develop flaws during their service lifetimes. Such flaws can affect the structural integrity of the part. Thus, it is important to know the "fracture toughness" of a structural part, or its ability to resist cracks. NASA has long experience in developing fracture toughness tests for aerospace hardware. Since 1960, NASA-Lewis has worked closely with the American Society for Testing & Materials. Lewis and NASA-funded industrial contractors have made many important contributions to test procedures, now recommended by ASTM, for measuring fracture toughness.
Determining collective barrier operation skew in a parallel computer
Faraj, Daniel A.
2015-11-24
Determining collective barrier operation skew in a parallel computer that includes a number of compute nodes organized into an operational group includes: for each of the nodes until each node has been selected as a delayed node: selecting one of the nodes as a delayed node; entering, by each node other than the delayed node, a collective barrier operation; entering, after a delay by the delayed node, the collective barrier operation; receiving an exit signal from a root of the collective barrier operation; and measuring, for the delayed node, a barrier completion time. The barrier operation skew is calculated by: identifying, from the compute nodes' barrier completion times, a maximum barrier completion time and a minimum barrier completion time and calculating the barrier operation skew as the difference of the maximum and the minimum barrier completion time.
OPERATIONAL MEASUREMENT OF COUPLING BY SKEW QUADRUPOLE MODULATION.
LUO.Y.CAMERON,P.LEE,R.ET AL.
2004-07-05
The measurement and correction of the residual betatron coupling via skew quadrupole modulation is a new diagnostics technique that has been developed and tested at the Relativistic Heavy Ion Collider (RHIC) as a very promising method for the linear decoupling on the ramp. By modulating the strengths of the skew quadrupole families the two eigentune modulations are precisely measured with a high resolution phase lock loop system. The projections of the residual coupling coefficient onto the skew quadrupole coupling modulation direction are determined. The residual linear coupling could be corrected according the measurement. We report the results from the dedicated beam studies carried on at RHIC injection, store and on the ramp. A capability of measuring coupling on the ramp opens possibility of continuous coupling corrections during acceleration.
Uniqueness: skews bit occurrence frequencies in randomly generated fingerprint libraries.
Chen, Nelson G
2016-08-01
Requiring that randomly generated chemical fingerprint libraries have unique fingerprints such that no two fingerprints are identical causes a systematic skew in bit occurrence frequencies, the proportion at which specified bits are set. Observed frequencies (O) at which each bit is set within the resulting libraries systematically differ from frequencies at which bits are set at fingerprint generation (E). Observed frequencies systematically skew toward 0.5, with the effect being more pronounced as library size approaches the compound space, which is the total number of unique possible fingerprints given the number of bit positions each fingerprint contains. The effect is quantified for varying library sizes as a fraction of the overall compound space, and for changes in the specified frequency E. The cause and implications for this systematic skew are subsequently discussed. When generating random libraries of chemical fingerprints, the imposition of a uniqueness requirement should either be avoided or taken into account.
Bayesian partial linear model for skewed longitudinal data.
Tang, Yuanyuan; Sinha, Debajyoti; Pati, Debdeep; Lipsitz, Stuart; Lipshultz, Steven
2015-07-01
Unlike majority of current statistical models and methods focusing on mean response for highly skewed longitudinal data, we present a novel model for such data accommodating a partially linear median regression function, a skewed error distribution and within subject association structures. We provide theoretical justifications for our methods including asymptotic properties of the posterior and associated semiparametric Bayesian estimators. We also provide simulation studies to investigate the finite sample properties of our methods. Several advantages of our method compared with existing methods are demonstrated via analysis of a cardiotoxicity study of children of HIV-infected mothers.
Power and Skew Aware Point Diffusion Clock Network
NASA Astrophysics Data System (ADS)
Jung, Gunok; Kim, Chunghee; Chae, Kyoungkuk; Park, Giho; Park, Sung Bae
This letter presents point diffusion clock network (PDCN) with local clock tree synthesis (CTS) scheme. The clock network is implemented with ten times wider metal line space than typical mesh networks for low power and utilized to nine times smaller area CTS execution for minimized clock skew amount. The measurement results show that skew amount of PDCN with local CTS is reduced to 36% and latency is shrunk to 45% of the amount in a 4.81mm2 CortexA-8 core with 65nm Samsung process.
Skewness of steady-state current fluctuations in nonequilibrium systems.
Belousov, Roman; Cohen, E G D; Wong, Chun-Shang; Goree, John A; Feng, Yan
2016-04-01
A skewness of the probability for instantaneous current fluctuations, in a nonequilibrium steady state, is observed experimentally in a dusty plasma. This skewness is attributed to the spatial asymmetry, which is imminent to the nonequilibrium systems due to the external hydrodynamic gradient. Using the modern framework of the large deviation theory, we extend the Onsager-Machlup ansatz for equilibrium fluctuations to systems with a preferred spatial direction, and provide a modulated Gaussian probability distribution, which is tested by simulations. This probability distribution is also of potential interest for other statistical disciplines. Connections with the principles of statistical mechanics, due to Boltzmann and Gibbs, are discussed as well. PMID:27176272
Severence, Timothy
1997-01-01
The Town Highway 66 crossing of the Locust Creek is a 41-ft-long, one-lane bridge consisting of a 39 ft steel stringer type bridge with a concrete deck (Vermont Agency of Transportation, written communication, August 24, 1994). The clear span is 36.8 ft. The bridge is supported by vertical, concrete abutments with wingwalls. The upstream right wingwall is protected by stone fill. The channel is skewed approximately 10 degrees to the opening while the opening-skew-to-roadway is 0 degrees. Additional details describing conditions at the site are included in the Level II Summary and Appendices D and E.
... artery. See also on this site: Ask a Texas Heart Institute Doctor: Search "myocardial bridge" Updated August ... comments. Terms of Use and Privacy Policy © Copyright Texas Heart Institute All rights reserved.
NASA Astrophysics Data System (ADS)
Zuk, W.
1981-06-01
Various methods states are employing to reduce the number of joints in bridge decks are surveyed. The most common method is the use of integral abutments, where the superstructure is jointed to a flexible type of abutment. New methods of reducing the number of joints in a bridge are analyzed mathematically, and from the analysis conclusions are drawn as to the feasibility of these methods.
Jiang, Zhaolin; Shen, Nuo; Zhou, Jianwei
2013-01-01
We first give the style spectral decomposition of a special skew circulant matrix C and then get the style decomposition of arbitrary skew circulant matrix by making use of the Kronecker products between the elements of first row in skew circulant and the special skew circulant C. Besides that, we obtain the singular value of skew circulant matrix as well. Finally, we deal with the optimal backward perturbation analysis for the linear system with skew circulant coefficient matrix on the base of its style spectral decomposition. PMID:24369488
Thermocline Feedback Influence on Indian Ocean Dipole Skewness
NASA Astrophysics Data System (ADS)
Ng, B.; Cai, W.; Walsh, K. J.
2014-12-01
A positive Indian Ocean Dipole (IOD) tends to have stronger cold sea surface temperature anomalies (SSTAs) over the eastern Indian Ocean with greater impacts than warm SSTAs that occur during its negative phase. These impacts from positive IODs range from drought over Australia and Indonesia, to flooding over East Africa and India. Two feedbacks have been suggested as the cause of positive IOD skewness, a positive Bjerknes feedback and a negative SST-cloud-radiation (SCR) feedback, but their relative importance is debated. Using models from phase 5 of the Coupled Model Intercomparison Project (CMIP5) and inter-model statistics, we show that the most important process for IOD skewness is an asymmetry in the thermocline feedback, whereby SSTAs respond to thermocline depth anomalies more strongly during the positive phase than negative phase. This asymmetric thermocline feedback drives IOD skewness despite positive IODs receiving greater damping from the SCR feedback. In response to global warming, although the thermocline feedback strengthens, its asymmetry between positive and negative IODs weakens. This behaviour change explains the reduction in IOD skewness that many models display under global warming.
Skewness and Comparability of School Based Continuous Assessment Scores
ERIC Educational Resources Information Center
Gbore, Lawrence Olu; Olabode, Abe Thomas; Olufemi, Adodo Sunday
2011-01-01
This study examined skewness as means of determining the nature of distribution of school based continuous assessment (SBCA) scores in selected subjects among Secondary Schools in Ondo State, Nigeria, to determine whether or not there is need for moderation of the SBCA Scores. This is an ex-post-facto research design involving no treatment and…
Root waving and skewing: unexpectedly in micro-g.
Roux, Stanley J
2012-12-07
Gravity has major effects on both the form and overall length of root growth. Numerous papers have documented these effects (over 300 publications in the last 5 years), the most well-studied being gravitropism, which is a growth re-orientation directed by gravity toward the earth's center. Less studied effects of gravity are undulations due to the regular periodic change in the direction root tips grow, called waving, and the slanted angle of growth roots exhibit when they are growing along a nearly-vertical surface, called skewing. Although diverse studies have led to the conclusion that a gravity stimulus is needed for plant roots to show waving and skewing, the novel results just published by Paul et al. (2012) reveal that this conclusion is not correct. In studies carried out in microgravity on the International Space Station, the authors used a new imaging system to collect digital photographs of plants every six hours during 15 days of spaceflight. The imaging system allowed them to observe how roots grew when their orientation was directed not by gravity but by overhead LED lights, which roots grew away from because they are negatively phototropic. Surprisingly, the authors observed both skewing and waving in spaceflight plants, thus demonstrating that both growth phenomena were gravity independent. Touch responses and differential auxin transport would be common features of root waving and skewing at 1-g and micro-g, and the novel results of Paul et al. will focus the attention of cell and molecular biologists more on these features as they try to decipher the signaling pathways that regulate root skewing and waving.
Arc voltage distribution skewness as an indicator of electrode gap during vacuum arc remelting
Williamson, Rodney L.; Zanner, Frank J.; Grose, Stephen M.
1998-01-01
The electrode gap of a VAR is monitored by determining the skewness of a distribution of gap voltage measurements. A decrease in skewness indicates an increase in gap and may be used to control the gap.
Correcting Quadrupole Roll in Magnetic Lenses with Skew Quadrupoles
Walstrom, Peter Lowell
2014-11-10
Quadrupole rolls (i.e. rotation around the magnet axis) are known to be a significant source of image blurring in magnetic quadrupole lenses. These rolls may be caused by errors in mechanical mounting of quadrupoles, by uneven radiation-induced demagnetization of permanent-magnet quadrupoles, etc. Here a four-quadrupole ×10 lens with so-called ”Russian” or A -B B-A symmetry is used as a model problem. Existing SLAC 1/2 in. bore high-gradient quadrupoles are used in the design. The dominant quadrupole roll effect is changes in the first-order part of the transfer map (the R matrix) from the object to the image plane (Note effects on the R matrix can be of first order in rotation angle for some R-matrix elements and second order in rotation angle for other elements, as shown below). It is possible to correct roll-induced image blur by mechanically adjusting the roll angle of one or more of the quadrupoles. Usually, rotation of one quadrupole is sufficient to correct most of the combined effect of rolls in all four quadrupoles. There are drawbacks to this approach, however, since mechanical roll correction requires multiple entries into experimental area to make the adjustments, which are made according to their effect on images. An alternative is to use a single electromagnetic skew quadrupole corrector placed either between two of the quadrupoles or after the fourth quadrupole (so-called “non-local” correction). The basic feasibility of skew quadrupole correction of quadrupole roll effects is demonstrated here. Rolls of the third lens quadrupole of up to about 1 milliradian can be corrected with a 15 cm long skew quadrupole with a gradient of up to 1 T/m. Since the effect of rolls of the remaining three lens quadrupoles are lower, a weaker skew quadrupole can be used to correct them. Non-local correction of quadrupole roll effects by skew quadrupoles is shown to be about one-half as effective as local correction (i.e. rotating individual quadrupoles to zero
Skewed Brownian Fluctuations in Single-Molecule Magnetic Tweezers
Burnham, Daniel R.; De Vlaminck, Iwijn; Henighan, Thomas; Dekker, Cees
2014-01-01
Measurements in magnetic tweezers rely upon precise determination of the position of a magnetic microsphere. Fluctuations in the position due to Brownian motion allows calculation of the applied force, enabling deduction of the force-extension response function for a single DNA molecule that is attached to the microsphere. The standard approach relies upon using the mean of position fluctuations, which is valid when the microsphere axial position fluctuations obey a normal distribution. However, here we demonstrate that nearby surfaces and the non-linear elasticity of DNA can skew the distribution. Through experiment and simulations, we show that such a skewing leads to inaccurate position measurements which significantly affect the extracted DNA extension and mechanical properties, leading to up to two-fold errors in measured DNA persistence length. We develop a simple, robust and easily implemented method to correct for such mismeasurements. PMID:25265383
SKEW QUADRUPOLES IN RHIC DIPOLE MAGNETS AT HIGH FIELDS.
JAIN, A.; GUPTA, P.; THOMPSON, P.; WANDERER, P.
1995-06-11
In the RHIC arc dipoles, the center of the cold mass lies above the center of the cryostat. At the maximum design field, the magnetic flux lines leak through the yoke to the asymmetrically located cryostat, which provides an additional return path. This introduces a systematic top-bottom asymmetry leading to a skew quadrupole term at high fields. A similar asymmetry is also created by any difference in weights of the upper and the lower yoke halves. Data from measurements of several RHIC dipoles are presented to study this effect. In the current production series of the RDIC dipoles, an attempt is made to compensate the effect of the cryostat by an asymmetry in the iron yoke. Seven dipoles with this type of yoke have been cold tested, and show a reduced saturation in the skew quadrupole term, as expected.
Quantifying Correlations via the Wigner-Yanase-Dyson Skew Information
NASA Astrophysics Data System (ADS)
Fan, Yajing; Cao, Huaixin
2016-09-01
In this paper, based on a discussion about the Wigner-Yanase-Dyson (WYD) skew information, the measure F a, α ( ρ a b ) for correlations in terms of the WYD skew information is introduced and discussed. The following conclusions are obtained. For a classical-quantum state ρ a b , F a, α ( ρ a b )=0 if and only if ρ a b is a product state; F a, α ( ρ a b ) is locally unitary invariant and convex on the set of states with the fixed marginal ρ a ; F a, α ( ρ a b ) decreases under local random unitary operation on H b ; For a quantum-classical state ρ a b , F a, α ( ρ a b ) decreases under local operation on H b ; Lastly, F a, α ( ρ a b ) is computed for the pure states and the Bell-diagonal states, respectively.
Identification of spots in rotated and skewed microarray images
NASA Astrophysics Data System (ADS)
Le Brese, Christopher; Zou, Ju Jia
2009-12-01
DNA microarray image processing has vast potential in the measurement of mass gene expression. A common approach to processing microarrays consists of spot identification, spot segmentation, and information extraction. We are concerned with spot identification. We aim to tackle the problem of identifying spots in rotated and skewed arrays via an automated process. The method proposed is composed of three steps, namely, array orientation calculation based on the Hough transform, affine calculation and correction, and gridding. The method is able to correctly identify spots in a microarray that has been rotated or skewed at an angle between 0 and +/-30 deg and corrupted by various types of noise such as high-intensity streaks, Gaussian noise, and salt-and-pepper noise.
Free vibration analyses of generally laminated tapered skew plates
NASA Astrophysics Data System (ADS)
Kapania, Rakesh K.; Singhvi, Sarvesh
1992-04-01
An efficient method is developed for the free vibration analyses of generally laminated composite skew plates having arbitrary edge conditions, such as clamped, simply supported or free. The procedure consists of the Rayleigh-Ritz method utilizing a strain energy functional containing both bending and stretching effects and accommodating arbitrary ply stacking sequences. A set of Chebyshev polynomials is used as trial functions to represent the three components of the displacement at a given point. The geometric boundary conditions are satisfied by providing appropriate springs with large stiffnesses at a given edge. Results are obtained for isotropic, specially orthotropic, symmetrically laminated and unsymmetrically laminated plates. Both rectangular and skewed tapered plates are analyzed. The capability to perform the static analysis of a composite plate is also demonstrated. To establish the correctness and effectiveness of the method, whenever possible, the numerical results are compared with those obtained by other researchers.
Universal relation between skewness and kurtosis in complex dynamics
NASA Astrophysics Data System (ADS)
Cristelli, Matthieu; Zaccaria, Andrea; Pietronero, Luciano
2012-06-01
We identify an important correlation between skewness and kurtosis for a broad class of complex dynamic systems and present a specific analysis of earthquake and financial time series. Two regimes of non-Gaussianity can be identified: a parabolic one, which is common in various fields of physics, and a power law one, with exponent 4/3, which at the moment appears to be specific of earthquakes and financial markets. For this property we propose a model and an interpretation in terms of very rare events dominating the statistics independently on the nature of the events considered. The predicted scaling relation between skewness and kurtosis matches very well the experimental pattern of the second regime. Regarding price fluctuations, this situation characterizes a universal stylized fact.
ERIC Educational Resources Information Center
Zito, Michael, Ed.
1999-01-01
This document is comprised of the two issues in volume 4 of "Bridges," a publication produced by the California Head Start-State Collaboration Office to detail the activities of the educational partnership and to provide relevant information to programs participating in the partnership. The spring 1999 issue focuses on the service system for…
ERIC Educational Resources Information Center
Silver, Michael, Ed.; Zito, Michael, Ed.
2002-01-01
This document is comprised of the one issue in volume 7 of "Bridges," a publication produced by the California Head Start-State Collaboration Office to detail the activities of the educational partnership and to provide relevant information to programs participating in the partnership. The Summer 2002 issue focuses on several topics of interest to…
NASA Technical Reports Server (NTRS)
1995-01-01
I-Bridge is a commercial version of software developed by I-Kinetics under a NASA Small Business Innovation Research (SBIR) contract. The software allows users of Windows applications to gain quick, easy access to databases, programs and files on UNIX services. Information goes directly onto spreadsheets and other applications; users need not manually locate, transfer and convert data.
ERIC Educational Resources Information Center
Wilcox, Bonita; Manear, John; Slifkin, Josh M.
This volume contains articles about writing, best practice, portfolio assessment, and technology, as well as original poetry and book reviews. Articles in the volume are: "Teaching Writing: Making Connections" (Eric Schott); "Empowering Teachers: A Success Story" (Sandra L. Krivak); "Bridging the Gap between the Classroom and Employment" (Linda C.…
Incorporating Skew into RMS Surface Roughness Probability Distribution
NASA Technical Reports Server (NTRS)
Stahl, Mark T.; Stahl, H. Philip.
2013-01-01
The standard treatment of RMS surface roughness data is the application of a Gaussian probability distribution. This handling of surface roughness ignores the skew present in the surface and overestimates the most probable RMS of the surface, the mode. Using experimental data we confirm the Gaussian distribution overestimates the mode and application of an asymmetric distribution provides a better fit. Implementing the proposed asymmetric distribution into the optical manufacturing process would reduce the polishing time required to meet surface roughness specifications.
Skew and twist resistant hydrodynamic rotary shaft seal
Dietle, Lannie; Kalsi, Manmohan Singh
1999-01-01
A hydrodynamically lubricated squeeze packing type rotary shaft seal suitable for lubricant retention and environmental exclusion which incorporates one or more resilient protuberances which and cooperate with the gland walls to hold the seal straight in its installation groove in unpressurized and low pressure lubricant retention applications thereby preventing skew-induced wear caused by impingement of abrasive contaminants present in the environment, and which also serve as radial bearings to prevent tipping of the seal within its installation gland.
Skew and twist resistant hydrodynamic rotary shaft seal
Dietle, L.; Kalsi, M.S.
1999-02-23
A hydrodynamically lubricated squeeze packing type rotary shaft seal suitable for lubricant retention and environmental exclusion which incorporates one or more resilient protuberances which cooperate with the gland walls to hold the seal straight in its installation groove in unpressurized and low pressure lubricant retention applications thereby preventing skew-induced wear caused by impingement of abrasive contaminants present in the environment, and which also serve as radial bearings to prevent tipping of the seal within its installation gland. 14 figs.
MEASURING LOCAL GRADIENT AND SKEW QUADRUPOLE ERRORS IN RHIC IRS.
CARDONA,J.; PEGGS,S.; PILAT,R.; PTITSYN,V.
2004-07-05
The measurement of local linear errors at RHIC interaction regions using an ''action and phase'' analysis of difference orbits has already been presented. This paper evaluates the accuracy of this technique using difference orbits that were taken when known gradient errors and skew quadrupole errors were intentionally introduced. It also presents action and phase analysis of simulated orbits when controlled errors are intentionally placed in a RHIC simulation model.
Bridged graphite oxide materials
NASA Technical Reports Server (NTRS)
Herrera-Alonso, Margarita (Inventor); McAllister, Michael J. (Inventor); Aksay, Ilhan A. (Inventor); Prud'homme, Robert K. (Inventor)
2010-01-01
Bridged graphite oxide material comprising graphite sheets bridged by at least one diamine bridging group. The bridged graphite oxide material may be incorporated in polymer composites or used in adsorption media.
Kurtosis, skewness, and non-Gaussian cosmological density perturbations
NASA Technical Reports Server (NTRS)
Luo, Xiaochun; Schramm, David N.
1993-01-01
Cosmological topological defects as well as some nonstandard inflation models can give rise to non-Gaussian density perturbations. Skewness and kurtosis are the third and fourth moments that measure the deviation of a distribution from a Gaussian. Measurement of these moments for the cosmological density field and for the microwave background temperature anisotropy can provide a test of the Gaussian nature of the primordial fluctuation spectrum. In the case of the density field, the importance of measuring the kurtosis is stressed since it will be preserved through the weakly nonlinear gravitational evolution epoch. Current constraints on skewness and kurtosis of primeval perturbations are obtained from the observed density contrast on small scales and from recent COBE observations of temperature anisotropies on large scales. It is also shown how, in principle, future microwave anisotropy experiments might be able to reveal the initial skewness and kurtosis. It is shown that present data argue that if the initial spectrum is adiabatic, then it is probably Gaussian, but non-Gaussian isocurvature fluctuations are still allowed, and these are what topological defects provide.
Caste load and the evolution of reproductive skew.
Holman, Luke
2014-01-01
Reproductive skew theory seeks to explain how reproduction is divided among group members in animal societies. Existing theory is framed almost entirely in terms of selection, though nonadaptive processes must also play some role in the evolution of reproductive skew. Here I propose that a genetic correlation between helper fecundity and breeder fecundity may frequently constrain the evolution of reproductive skew. This constraint is part of a wider phenomenon that I term "caste load," which is defined as the decline in mean fitness caused by caste-specific selection pressures, that is, differential selection on breeding and nonbreeding individuals. I elaborate the caste load hypothesis using quantitative and population genetic arguments and individual-based simulations. Although selection can sometimes erode genetic correlations and resolve caste load, this may be constrained when mutations have similar pleiotropic effects on breeder and helper traits. I document evidence for caste load, identify putative genomic adaptations to it, and suggest future research directions. The models highlight the value of considering adaptation within the boundaries imposed by genetic architecture and incidentally reaffirm that monogamy promotes the evolutionary transition to eusociality. PMID:24334738
Validation of an Acoustic Impedance Prediction Model for Skewed Resonators
NASA Technical Reports Server (NTRS)
Howerton, Brian M.; Parrott, Tony L.
2009-01-01
An impedance prediction model was validated experimentally to determine the composite impedance of a series of high-aspect ratio slot resonators incorporating channel skew and sharp bends. Such structures are useful for packaging acoustic liners into constrained spaces for turbofan noise control applications. A formulation of the Zwikker-Kosten Transmission Line (ZKTL) model, incorporating the Richards correction for rectangular channels, is used to calculate the composite normalized impedance of a series of six multi-slot resonator arrays with constant channel length. Experimentally, acoustic data was acquired in the NASA Langley Normal Incidence Tube over the frequency range of 500 to 3500 Hz at 120 and 140 dB OASPL. Normalized impedance was reduced using the Two-Microphone Method for the various combinations of channel skew and sharp 90o and 180o bends. Results show that the presence of skew and/or sharp bends does not significantly alter the impedance of a slot resonator as compared to a straight resonator of the same total channel length. ZKTL predicts the impedance of such resonators very well over the frequency range of interest. The model can be used to design arrays of slot resonators that can be packaged into complex geometries heretofore unsuitable for effective acoustic treatment.
Tide and skew surge independence: New insights for flood risk
NASA Astrophysics Data System (ADS)
Williams, Joanne; Horsburgh, Kevin J.; Williams, Jane A.; Proctor, Robert N. F.
2016-06-01
Storm surges are a significant hazard to coastal communities around the world, putting lives at risk and costing billions of dollars in damage. Understanding how storm surges and high tides interact is crucial for estimating extreme water levels so that we can protect coastal communities. We demonstrate that in a tidal regime the best measure of a storm surge is the skew surge, the difference between the observed and predicted high water within a tidal cycle. Based on tide gauge records spanning decades from the UK, U.S., Netherlands, and Ireland we show that the magnitude of high water exerts no influence on the size of the most extreme skew surges. This is the first systematic proof that any storm surge can occur on any tide, which is essential for understanding worst-case scenarios. The lack of surge generation dependency on water depth emphasizes the dominant natural variability of weather systems in an observation-based analysis. Weak seasonal relationships between skew surges and high waters were identified at a minority of locations where long-period changes to the tidal cycle interact with the storm season. Our results allow advances to be made in methods for estimating the joint probabilities of storm surges and tides.
ERIC Educational Resources Information Center
Murfin, Brian
2000-01-01
Describes the famous swing bridge in Belize. Students build bridges from a variety of materials and answer the questions, What are different types of bridges?, How do bridges work?, How can you tell if a bridge design will be safe?, and What is the best way to build a bridge over a river while still allowing boat traffic? (SAH)
Bridge Inspector's Training Manual.
ERIC Educational Resources Information Center
Federal Highway Administration (DOT), Washington, DC. Bureau of Public Roads.
A guide for the instruction of bridge inspectors is provided in this manual as well as instructions for conducting and reporting on a bridge inspection. The chapters outline the qualifications necessary to become a bridge inspector. The subject areas covered are: The Bridge Inspector, Bridge Structures, Bridge Inspection Reporting System,…
Skew And Twist Resistant Hydrodynamic Rotary Shaft Seal
Dietle, Lannie; Kalsi, Manmohan Singh
2000-03-14
A hydrodynamically lubricated squeeze packing type rotary shaft seal suitable for lubricant retention and environmental exclusion which incorporates one or more resilient protuberances which and cooperate with the gland walls to hold the seal straight in its installation groove in unpressurized and low pressure lubricant retention applications thereby preventing skew-induced wear caused by impingement of abrasive contaminants present in the environment, and which also serve as radial bearings to prevent tipping of the seal within its installation gland. Compared to prior art, this invention provides a dramatic reduction of seal and shaft wear in abrasive environments and provides a significant increase in seal life.
Light transmission for polymer fibers using skew and meridional rays
NASA Astrophysics Data System (ADS)
Tekelioglu, Murat
This dissertation is concerned with the development of a light transmission model for polymer optical fibers having application in hybrid solar lighting (HSL) systems. Conceptually, the HSL system consists of a solar collector/receiver that focuses concentrated visible solar light onto a polymer optical fiber (up to 10-m-long) that transports the solar light to an interior space. For this study, the polymer optical fiber is a large-core (0.2-40 mm diameter) plastic optical fiber (POF) comprised of various lengths of straight and bent sections. Although there has been extensive research on the transmission of monochromatic light through optical fibers for the communications industry, there are relatively few publications for visible light transmission through POFs. These publications were critically reviewed in this research. It is shown that the light transmission can be described with either skew or meridional rays. For each ray type, the HSL system light transmission was determined as a function of fiber geometrical properties (core and cladding radii, bend radius, bend angle, and fiber length) and optical properties (core and clad refractive indices, absorption and scattering coefficients, core-clad rms roughness height, and core-clad interface defects loss coefficient). To do this, first, models were developed for separate straight and bent sections for multiple skew and meridional rays. Second, the straight and bent models were combined into a FORTRAN simulation program for an arbitrary fiber with a combination of arbitrary straight and bent sections. The input condition of the rays (arrangement of rays, incident angle, and intensity profile) is user-defined. Third, the simulation results were experimentally validated using two different POFs, twelve configurations of straight and bent fiber subsystems, and two ray types. These experimental comparisons show that the transmission model using meridional rays is slightly better than that with the skew rays. But
Wigner-Yanase skew information as tests for quantum entanglement
Chen Zeqian
2005-05-15
A Bell-type inequality is proposed in terms of Wigner-Yanase skew information, which is quadratic and involves only one local spin observable at each site. This inequality presents a hierarchic classification of all states of multipartite quantum systems from separable to fully entangled states, which is more powerful than the one presented by quadratic Bell inequalities from two-entangled to fully entangled states. In particular, it is proved that the inequality provides an exact test to distinguish entangled from nonentangled pure states of two qubits. Our inequality sheds considerable light on relationships between quantum entanglement and information theory.
Effect of Resonator Axis Skew on Normal Incidence Impedance
NASA Technical Reports Server (NTRS)
Parrott, Tony L.; Jones, Michael G.; Homeijer, Brian
2003-01-01
High by-pass turbofan engines have fewer fan blades and lower rotation speeds than their predecessors. Consequently, the noise suppression at the low frequency end of the noise spectra has become an increasing concern. This has led to a renewed emphasis on improving noise suppression efficiency of passive, duct liner treatments at the lower frequencies. For a variety of reasons, passive liners are comprised of locally-reacting, resonant absorbers. One reason for this design choice is to satisfy operational and economic requirements. The simplest liner design consists of a single layer of honeycomb core sandwiched between a porous facesheet and an impervious backing plate. These resonant absorbing structures are integrated into the nacelle wall and are very ef- ficient over a limited bandwidth centered on their resonance frequency. Increased noise suppression bandwidth and greater suppression at lower frequencies is typically achieved for conventional liners by increasing the liner depth and incorporating thin porous septa into the honeycomb core. However, constraints on liner depth in modern high by-pass engine nacelles severely limit the suppression bandwidth extension to lower frequencies. Also, current honeycomb core liners may not be suitable for irregular geometric volumes heretofore not considered. It is of interest, therefore, to find ways to circumvent liner depth restrictions and resonator cavity shape constraints. One way to increase effective liner depth is to skew the honeycomb core axis relative to the porous facesheet surface. Other possibilities are to alter resonator cavity shape, e.g. high aspect ratio, narrow channels that possibly include right angle bends, 180. channel fold-backs, and splayed channel walls to conform to irregular geometric constraints. These possibilities constitute the practical motivation for expanding impedance modeling capability to include unconventional resonator orientations and shapes. The work reported in this paper is
Pattern formation of underwater sand ripples with a skewed drive.
Bundgaard, F; Ellegaard, C; Scheibye-Knudsen, K; Bohr, T; Sams, T
2004-12-01
In this paper we present an experimental study of the dynamics of underwater sand ripples when a regular pattern of ripples is subjected to a skewed oscillatory flow, i.e., one not perpendicular to the direction of the ripple crests. Striking patterns with new, superposed ripples on top of the original ones occur very quickly with a characteristic angle, which is, in general, not perpendicular to the flow. A slower, more complex transition then follows, leading to the final state where the ripples are again perpendicular to the flow. We investigate the variation of the superposed pattern as a function of the direction, amplitude, and frequency of the drive, and as a function of the viscosity (by changing the temperature). We quantify the dynamics of the entire transition process and finally study the grain motion around idealized (solid) skewed ripples. This leads to a characteristic mean path of a single particle. The path has a shape close to a parallelogram, with no apparent connection to the pattern of real, superposed ripples. On the other hand, a thin layer of sand sprinkled on the solid ripples leads to qualitatively similar patterns.
Characterising Uncertainty in Expert Assessments: Encoding Heavily Skewed Judgements
O’Leary, Rebecca A.; Low-Choy, Samantha; Fisher, Rebecca; Mengersen, Kerrie; Caley, M. Julian
2015-01-01
When limited or no observed data are available, it is often useful to obtain expert knowledge about parameters of interest, including point estimates and the uncertainty around these values. However, it is vital to elicit this information appropriately in order to obtain valid estimates. This is particularly important when the experts’ uncertainty about these estimates is strongly skewed, for instance when their best estimate is the same as the lowest value they consider possible. Also this is important when interest is in the aggregation of elicited values. In this paper, we compare alternative distributions for describing such estimates. The distributions considered include the lognormal, mirror lognormal, Normal and scaled Beta. The case study presented here involves estimation of the number of species in coral reefs, which requires eliciting counts within broader taxonomic groups, with highly skewed uncertainty estimates. This paper shows substantial gain in using the scaled Beta distribution, compared with Normal or lognormal distributions. We demonstrate that, for this case study on counting species, applying the novel encoding methodology developed in this paper can facilitate the acquisition of more rigorous estimates of (hierarchical) count data and credible bounds. The approach can also be applied to the more general case of enumerating a sampling frame via elicitation. PMID:26517835
Multiple mating and reproductive skew in Trinidadian guppies.
Becher, S. A.; Magurran, A. E.
2004-01-01
Male offspring production in promiscuously mating species is typically more skewed than female offspring production. It is therefore advantageous for males to seek as many mating partners as possible. However, given the documented benefits of polyandry we expect females, as well as males, to mate multiply. We tested these ideas using Trinidadian guppies, Poecilia reticulata. Fishes were collected from the wild, housed in groups of 10 males and 10 females and allowed to reproduce freely over a period of three months. We used hypervariable microsatellite loci to identify the parents of 840 offspring and to quantify the variance in mating success. As anticipated, and in line with the Bateman gradient, there was greater skew in the number of progeny produced by males. By contrast, we found no sex difference in mating partner number over the duration of the experiment. A median of two males fathered each brood and there was marked turnover in the identities of the sires of successive broods. Female partner turnover was, however, less than expected under random mating. We suggest that partner switching over time, as well as polyandry within broods, could contribute to the maintenance of genetic diversity in guppy populations. PMID:15293853
Crossover ensembles of random matrices and skew-orthogonal polynomials
Kumar, Santosh; Pandey, Akhilesh
2011-08-15
Highlights: > We study crossover ensembles of Jacobi family of random matrices. > We consider correlations for orthogonal-unitary and symplectic-unitary crossovers. > We use the method of skew-orthogonal polynomials and quaternion determinants. > We prove universality of spectral correlations in crossover ensembles. > We discuss applications to quantum conductance and communication theory problems. - Abstract: In a recent paper (S. Kumar, A. Pandey, Phys. Rev. E, 79, 2009, p. 026211) we considered Jacobi family (including Laguerre and Gaussian cases) of random matrix ensembles and reported exact solutions of crossover problems involving time-reversal symmetry breaking. In the present paper we give details of the work. We start with Dyson's Brownian motion description of random matrix ensembles and obtain universal hierarchic relations among the unfolded correlation functions. For arbitrary dimensions we derive the joint probability density (jpd) of eigenvalues for all transitions leading to unitary ensembles as equilibrium ensembles. We focus on the orthogonal-unitary and symplectic-unitary crossovers and give generic expressions for jpd of eigenvalues, two-point kernels and n-level correlation functions. This involves generalization of the theory of skew-orthogonal polynomials to crossover ensembles. We also consider crossovers in the circular ensembles to show the generality of our method. In the large dimensionality limit, correlations in spectra with arbitrary initial density are shown to be universal when expressed in terms of a rescaled symmetry breaking parameter. Applications of our crossover results to communication theory and quantum conductance problems are also briefly discussed.
Experimental and finite element studies on free vibration of skew plates
NASA Astrophysics Data System (ADS)
Srinivasa, C. V.; Suresh, Y. J.; Prema Kumar, W. P.
2014-03-01
The present paper deals with the experimental and finite element studies carried out on free vibration of isotropic and laminated composite skew plates. The natural frequencies were determined using CQUAD8 finite element of MSC/NASTRAN and comparison made between the experimental values and the finite element solution. The effects of the skew angle and aspect ratio on the natural frequencies of isotropic skew plates were studied. The effects of skew angle, aspect ratio, fiber orientation angle and laminate stacking sequence (keeping total number of layers in the laminate constant) on the natural frequencies of antisymmetric laminated composite skew plates were also studied. The experimental values of the natural frequencies are in good agreement with the finite element solution. The natural frequencies generally increase with an increase in the skew angle for any given value of aspect ratio.
Bandyopadhyay, Dipankar; Lachos, Victor H.; Castro, Luis M.; Dey, Dipak K.
2012-01-01
Often in biomedical studies, the routine use of linear mixed-effects models (based on Gaussian assumptions) can be questionable when the longitudinal responses are skewed in nature. Skew-normal/elliptical models are widely used in those situations. Often, those skewed responses might also be subjected to some upper and lower quantification limits (viz. longitudinal viral load measures in HIV studies), beyond which they are not measurable. In this paper, we develop a Bayesian analysis of censored linear mixed models replacing the Gaussian assumptions with skew-normal/independent (SNI) distributions. The SNI is an attractive class of asymmetric heavy-tailed distributions that includes the skew-normal, the skew-t, skew-slash and the skew-contaminated normal distributions as special cases. The proposed model provides flexibility in capturing the effects of skewness and heavy tail for responses which are either left- or right-censored. For our analysis, we adopt a Bayesian framework and develop a MCMC algorithm to carry out the posterior analyses. The marginal likelihood is tractable, and utilized to compute not only some Bayesian model selection measures but also case-deletion influence diagnostics based on the Kullback-Leibler divergence. The newly developed procedures are illustrated with a simulation study as well as a HIV case study involving analysis of longitudinal viral loads. PMID:22685005
NASA Astrophysics Data System (ADS)
Liu, Yufang; Zhang, Weiguo; Fu, Junhui
2016-11-01
This paper presents the Binomial Markov-switching Multifractal (BMSM) model of asset returns with Skewed t innovations (BMSM-Skewed t for short), which considers the fat tails, skewness and multifractality in asset returns simultaneously. The parameters of BMSM-Skewed t model can be estimated by Maximum Likelihood (ML) methods, and volatility forecasting can be accomplished via Bayesian updating. In order to evaluate the performance of BMSM-Skewed t model, BMSM model with Normal innovations (BMSM-N), BMSM model with Student-t innovations (BMSM-t) and GARCH(1,1) models (GARCH-N, GARCH-t and GARCH-Skewed t) are chosen for comparison. Through empirical studies on Shanghai Stock Exchange Composite Index (SSEC), we find that for sample estimation, BMSM models outperform the GARCH(1,1) models through BIC and AIC rules, and BMSM-Skewed t performs the best among all the models due to its fat tails, skewness and multifractality. In addition, BMSM-Skewed t model dominates other models at most forecasting horizons for out-of-sample volatility forecasts in terms of MSE, MAE and SPA test.
Skewness and shock formation in laboratory-scale supersonic jet data.
Gee, Kent L; Neilsen, Tracianne B; Atchley, Anthony A
2013-06-01
Spatial properties of noise statistics near unheated, laboratory-scale supersonic jets yield insights into source characteristics and near-field shock formation. Primary findings are (1) waveforms with positive pressure skewness radiate from the source with a directivity upstream of maximum overall level and (2) skewness of the time derivative of the pressure waveforms increases significantly with range, indicating formation of shocks during propagation. These results corroborate findings of a previous study involving full-scale engine data. Further, a comparison of ideally and over-expanded laboratory data show that while derivative skewness maps are similar, waveform skewness maps are substantially different for the two cases. PMID:23742445
O'Connell, Megan E; Tuokko, Holly; Kadlec, Helena
2011-04-01
Demographic corrections for cognitive tests should improve classification accuracy by reducing age or education biases, but empirical support has been equivocal. Using a simulation procedure, we show that creating moderate or extreme skewness in cognitive tests compromises the classification accuracy of demographic corrections, findings that appear replicated within clinical data for the few neuropsychological test scores with an extreme degree of skew. For most neuropsychological tests, the dementia classification accuracy of raw and demographically corrected scores was equivalent. These findings suggest that the dementia classification accuracy of demographic corrections is robust to slight degrees of skew (i.e., skewness <1.5). PMID:21154077
COMPENSATION OF FAST KICKER ROLLS WITH SKEW QUADRUPOLES
Pinayev, I.
2011-03-28
The development of the third generation light sources lead to the implementation of the top-up operation, when injection occurs while users collect data. The beam excursions due to the non-closure of the injection bump can spoil the data and need to be suppressed. In the horizontal plane compensation can be achieved by adjusting timing and kick amplitudes. The rolls of the kicker magnets create non-closure in the vertical plane and usually there is no means for correction. In the paper we describe proposed compensation scheme utilizing two skew quadrupoles placed inside the injection bump. The third generation light sources implement top-up operation firstly introduced at Advanced Photon Source. In this mode the circulating beam current is supported near constant by frequent injection of small charge, while photon beam is delivered for users. The beam perturbations caused by the mismatched injection bump can provide undesired noise in the user data. Usually the injection trigger is distributed to the users end stations so that those affected would be able to blank data acquisition. Nevertheless, as good operational practice such transients should be suppressed as much as possible. In the horizontal plane (which is commonly used for injection) one can adjust individual kicker strength as well as trigger delay while observing motion of the stored beam centroid. In the vertical plane such means are unavailable in the most cases. The possible solutions include dedicated weak vertical kickers and motorized adjustment of the roll angle of the injection kickers. Both abovementioned approaches are expensive and can significantly deteriorate reliability. We suggest two employ two skew quadrupoles (to correct both angle and position) placed inside the injection bump. In this case the beam position itself serves as measure of the kicker strength (assuming that kickers are well matched) and vertical kicks from the skew quadrupoles will be self synchronized with injection bump
THE TRUSS BRIDGE SEGMENT OF THE TRIBOROUGH BRIDGE IN FOREGROUND ...
THE TRUSS BRIDGE SEGMENT OF THE TRIBOROUGH BRIDGE IN FOREGROUND AND THE HELL GATE BRIDGE IN THE BACKGROUND ADJACENT TO THE SUSPENSION SEGMENT OF THE TRIBOROUGH BRIDGE. - Triborough Bridge, Passing through Queens, Manhattan & the Bronx, Queens (subdivision), Queens County, NY
Cracked shells under skew-symmetric loading. [Reissner theory
NASA Technical Reports Server (NTRS)
Delale, F.
1981-01-01
The general problem of a shell containing a through crack in one of the principal planes of curvature and under general skew-symmetric loading is considered. By employing a Reissner type shell theory which takes into account the effect of transverse shear strains, all boundary conditions on the crack surfaces are satisfied separately. Consequently, unlike those obtained from the classical shell theory, the angular distributions of the stress components around the crack tips are shown to be identical to the distributions obtained from the plane and anti-plane elasticity solutions. Results are given for axially and circumferentially cracked cylindrical shells, spherical shells, and toroidal shells under uniform in-plane shearing, out of plane shearing, and torsion. The problem is formulated for specially orthostropic materials, therefore, the effect of orthotropy on the results is also studied.
Soft bounds on diffusion produce skewed distributions and Gompertz growth.
Mandrà, Salvatore; Lagomarsino, Marco Cosentino; Gherardi, Marco
2014-09-01
Constraints can affect dramatically the behavior of diffusion processes. Recently, we analyzed a natural and a technological system and reported that they perform diffusion-like discrete steps displaying a peculiar constraint, whereby the increments of the diffusing variable are subject to configuration-dependent bounds. This work explores theoretically some of the revealing landmarks of such phenomenology, termed "soft bound." At long times, the system reaches a steady state irreversibly (i.e., violating detailed balance), characterized by a skewed "shoulder" in the density distribution, and by a net local probability flux, which has entropic origin. The largest point in the support of the distribution follows a saturating dynamics, expressed by the Gompertz law, in line with empirical observations. Finally, we propose a generic allometric scaling for the origin of soft bounds. These findings shed light on the impact on a system of such "scaling" constraint and on its possible generating mechanisms.
Soft bounds on diffusion produce skewed distributions and Gompertz growth
NASA Astrophysics Data System (ADS)
Mandrà, Salvatore; Lagomarsino, Marco Cosentino; Gherardi, Marco
2014-09-01
Constraints can affect dramatically the behavior of diffusion processes. Recently, we analyzed a natural and a technological system and reported that they perform diffusion-like discrete steps displaying a peculiar constraint, whereby the increments of the diffusing variable are subject to configuration-dependent bounds. This work explores theoretically some of the revealing landmarks of such phenomenology, termed "soft bound." At long times, the system reaches a steady state irreversibly (i.e., violating detailed balance), characterized by a skewed "shoulder" in the density distribution, and by a net local probability flux, which has entropic origin. The largest point in the support of the distribution follows a saturating dynamics, expressed by the Gompertz law, in line with empirical observations. Finally, we propose a generic allometric scaling for the origin of soft bounds. These findings shed light on the impact on a system of such "scaling" constraint and on its possible generating mechanisms.
Restoring the skew quadrupole moment in the Tevatron dipoles
Harding, D.J.; Bauer, P.C.; Blowers, J.N.; DiMarco, J.; Glass, H.D.; Hanft, R.W.; Carson, J.A.; Robotham, W.F.; Tartaglia, M.A.; Tompkins, J.C.; Velev, G.; /Fermilab
2005-05-01
In early 2003 it was realized that mechanical changes in the Tevatron dipoles had led to a deterioration of the magnetic field quality that was hindering operation of the accelerator. After extensive study, a remediation program was started in late 2003 that will continue through 2005. The mechanical and magnetic effects are discussed. The readjustment process and experience are reported, along with other observations on aging magnets. In January 2003 two lines of inquiry converged, leading to the recognition that the severe betatron coupling that was hindering operation of the Tevatron could be explained by a systematic shift on the skew quadrupole field in the dipole magnets of the same size expected from observed mechanical movement of the coils inside the magnet yokes [1]. This paper reports on subsequent magnet studies that were conducted in parallel with additional beam studies and accelerator modeling [2] exploring the feasibility of the eventual remediation effort [3].
GC skew is a conserved property of unmethylated CpG island promoters across vertebrates
Hartono, Stella R.; Korf, Ian F.; Chédin, Frédéric
2015-01-01
GC skew is a measure of the strand asymmetry in the distribution of guanines and cytosines. GC skew favors R-loops, a type of three stranded nucleic acid structures that form upon annealing of an RNA strand to one strand of DNA, creating a persistent RNA:DNA hybrid. Previous studies show that GC skew is prevalent at thousands of human CpG island (CGI) promoters and transcription termination regions, which correspond to hotspots of R-loop formation. Here, we investigated the conservation of GC skew patterns in 60 sequenced chordates genomes. We report that GC skew is a conserved sequence characteristic of the CGI promoter class in vertebrates. Furthermore, we reveal that promoter GC skew peaks at the exon 1/ intron1 junction and that it is highly correlated with gene age and CGI promoter strength. Our data also show that GC skew is predictive of unmethylated CGI promoters in a range of vertebrate species and that it imparts significant DNA hypomethylation for promoters with intermediate CpG densities. Finally, we observed that terminal GC skew is conserved for a subset of vertebrate genes that tend to be located significantly closer to their downstream neighbors, consistent with a role for R-loop formation in transcription termination. PMID:26253743
A proof for Rhiel's range estimator of the coefficient of variation for skewed distributions.
Rhiel, G Steven
2007-02-01
In this research study is proof that the coefficient of variation (CV(high-low)) calculated from the highest and lowest values in a set of data is applicable to specific skewed distributions with varying means and standard deviations. Earlier Rhiel provided values for d(n), the standardized mean range, and a(n), an adjustment for bias in the range estimator of micro. These values are used in estimating the coefficient of variation from the range for skewed distributions. The d(n) and an values were specified for specific skewed distributions with a fixed mean and standard deviation. In this proof it is shown that the d(n) and an values are applicable for the specific skewed distributions when the mean and standard deviation can take on differing values. This will give the researcher confidence in using this statistic for skewed distributions regardless of the mean and standard deviation.
Flexural Vibration Of Skew Mindlin Plates With Oblique Internal Line Supports
NASA Astrophysics Data System (ADS)
Xiang, Y.; Kitipornchai, S.; Liew, K. M.; Wang, C. M.
1994-12-01
A free vibration analysis of moderately thick skew plates with oblique internal line supports is presented. Mindlin's plate theory is employed and the pb -2 Rayleigh-Ritz method is applied to obtain the governing eigenvalue equation for internally supported skew plates. A set of natural frequencies for skew Mindlin plates with oblique internal line supports having different combinations of boundary conditions has been determined for various aspect ratios a/b, relative thickness ratios t/b and skew angles α. The validity of the approach is illustrated by comparing the results with other established values. From literature searches, it appears that no work has previously been done on the free vibration of moderately thick skew plates with oblique internal line supports. Thus this paper may provide some important information to designers and engineers for use in practical applications.
Skewness of cloud droplet spectrum and an improved estimation for its relative dispersion
NASA Astrophysics Data System (ADS)
Liu, Yu; Lu, Chunsong; Li, Weiliang
2016-05-01
The relative dispersion of the cloud droplet spectrum is a very important parameter in describing and modeling cloud microphysical processes. Based on the definition of skewness as well as theoretical and data analyses, a linear fitting relationship (α = 2.91ɛ-0.59) between skewness (α) and relative dispersion (ɛ) is established and a new method is developed to estimate the relative dispersion of the cloud droplet spectrum. The new method does not depend on any assumption of a particular distribution for the cloud droplet spectrum and has broader applicability than the previous methods. Comparisons of the three methods for the relative dispersion with the observed data supported the following conclusions. (1) The skewness of the cloud droplet spectrum is asymmetrically distributed. An assumption of zero skewness in quantifying the relative dispersion inevitably results in relatively large deviations from the observations. Errors of the estimated relative dispersion due to the omission of the skewness term are not solely related to the skewness, but rather to the product of the skewness and relative dispersion. (2) The use of the assumption that the cloud droplet spectrum takes a gamma distribution is similar to the assumption that the skewness is twice the relative dispersion. This leads to a better accuracy in estimating the relative dispersion than that with zero skewness assumption. (3) Comparisons with observations show that the new method is more accurate than the one under gamma distribution assumption and is the best among all the three methods. (4) It is believed that finding a better correlation between the skewness and the relative dispersion would further reduce the deviations for the estimated relative dispersion.
Skew redundant MEMS IMU calibration using a Kalman filter
NASA Astrophysics Data System (ADS)
Jafari, M.; Sahebjameyan, M.; Moshiri, B.; Najafabadi, T. A.
2015-10-01
In this paper, a novel calibration procedure for skew redundant inertial measurement units (SRIMUs) based on micro-electro mechanical systems (MEMS) is proposed. A general model of the SRIMU measurements is derived which contains the effects of bias, scale factor error and misalignments. For more accuracy, the effect of lever arms of the accelerometers to the center of the table are modeled and compensated in the calibration procedure. Two separate Kalman filters (KFs) are proposed to perform the estimation of error parameters for gyroscopes and accelerometers. The predictive error minimization (PEM) stochastic modeling method is used to simultaneously model the effect of bias instability and random walk noise on the calibration Kalman filters to diminish the biased estimations. The proposed procedure is simulated numerically and has expected experimental results. The calibration maneuvers are applied using a two-axis angle turntable in a way that the persistency of excitation (PE) condition for parameter estimation is met. For this purpose, a trapezoidal calibration profile is utilized to excite different deterministic error parameters of the accelerometers and a pulse profile is used for the gyroscopes. Furthermore, to evaluate the performance of the proposed KF calibration method, a conventional least squares (LS) calibration procedure is derived for the SRIMUs and the simulation and experimental results compare the functionality of the two proposed methods with each other.
Time Variations of Scour Below Submerged Skewed Pipelines
NASA Astrophysics Data System (ADS)
Yusoff, M. A. M.; Azamathulla, H. M.; Ghani, A. A.
2016-07-01
The presence of pipe across river initiates the piping effect combined with the stagnation eddy and vortex system in the vicinity of the pipeline. The main objective of the research is to investigate the physics of scour below skewed pipeline in river crossing as well as the time variations of the scour development. In this study, the experiments were conducted for four different angles of pipe (30°, 45°, 60° and 90°) across a channel and placed on the sediment bed with e/D = 0. The scour development for flow shallowness y/D = 3 and y/D = 4, initiated at downstream side of the pipe, where the bed sediment appeared to be ejected from the bed due to the piping effect process. At the initial stage, the scour process for 150mm flow depth enlarged rapidly. Whilst, the scour process for 200 mm flow depth slowly developed and after certain time, the sediment bed scoured rapidly. The scour depth increased considerably at development stage and the suspended load near the bed especially below the pipe decreased significantly compared to the initial stage. The rate of sediment eroded from the sediment bed decreased at the stabilization phase. The equilibrium phase of the scour depth considered achieved as the dimensions of the scour hole do not change significantly.
Abundant rich phase transitions in step-skew products
NASA Astrophysics Data System (ADS)
Díaz, L. J.; Gelfert, K.; Rams, M.
2014-09-01
We study phase transitions for the topological pressure of geometric potentials of transitive sets. The sets considered are partially hyperbolic having a step-skew product dynamics over a horseshoe with one-dimensional fibres corresponding to the central direction. The sets are genuinely non-hyperbolic, containing intermingled horseshoes of different hyperbolic, behaviour (contracting and expanding centre). We construct for every k ⩾ 1 a diffeomorphism F with a transitive set Λ as above such that the pressure map P(t) = P(t φ) of the potential \\varphi= -log \\,\\Vert \\rmd F|_{E^c}\\Vert (Ec the central direction) defined on Λ has k rich phase transitions. This means that there are parameters tℓ, ℓ = 0, …, k - 1, where P(t) is not differentiable and this lack of differentiability is due to the coexistence of two equilibrium states of tℓ φ with positive entropy and different Birkhoff averages. Each phase transition is associated with a gap in the central Lyapunov spectrum of F on Λ.
Regression for skewed biomarker outcomes subject to pooling.
Mitchell, Emily M; Lyles, Robert H; Manatunga, Amita K; Danaher, Michelle; Perkins, Neil J; Schisterman, Enrique F
2014-03-01
Epidemiological studies involving biomarkers are often hindered by prohibitively expensive laboratory tests. Strategically pooling specimens prior to performing these lab assays has been shown to effectively reduce cost with minimal information loss in a logistic regression setting. When the goal is to perform regression with a continuous biomarker as the outcome, regression analysis of pooled specimens may not be straightforward, particularly if the outcome is right-skewed. In such cases, we demonstrate that a slight modification of a standard multiple linear regression model for poolwise data can provide valid and precise coefficient estimates when pools are formed by combining biospecimens from subjects with identical covariate values. When these x-homogeneous pools cannot be formed, we propose a Monte Carlo expectation maximization (MCEM) algorithm to compute maximum likelihood estimates (MLEs). Simulation studies demonstrate that these analytical methods provide essentially unbiased estimates of coefficient parameters as well as their standard errors when appropriate assumptions are met. Furthermore, we show how one can utilize the fully observed covariate data to inform the pooling strategy, yielding a high level of statistical efficiency at a fraction of the total lab cost. PMID:24521420
Statistics on Cannabis Users Skew Perceptions of Cannabis Use
Burns, Rachel M.; Caulkins, Jonathan P.; Everingham, Susan S.; Kilmer, Beau
2013-01-01
Collecting information about the prevalence of cannabis use is necessary but not sufficient for understanding the size, dynamics, and outcomes associated with cannabis markets. This paper uses two data sets describing cannabis consumption in the United States and Europe to highlight (1) differences in inferences about sub-populations based on the measure used to quantify cannabis-related activity; (2) how different measures of cannabis-related activity can be used to more accurately describe trends in cannabis usage over time; and (3) the correlation between frequency of use in the past-month and average grams consumed per use-day. Key findings: focusing on days of use instead of prevalence shows substantially greater increases in U.S. cannabis use in recent years; however, the recent increase is mostly among adults, not youth. Relatively more rapid growth in use days also occurred among the college-educated and Hispanics. Further, data from a survey conducted in seven European countries show a strong positive correlation between frequency of use and quantity consumed per day of use, suggesting consumption is even more skewed toward the minority of heavy users than is suggested by days-of-use calculations. PMID:24223560
Field, J; Solís, C R; Queller, D C; Strassmann, J E
1998-06-01
Recent models postulate that the members of a social group assess their ecological and social environments and agree a "social contract" of reproductive partitioning (skew). We tested social contracts theory by using DNA microsatellites to measure skew in 24 cofoundress associations of paper wasps, Polistes bellicosus. In contrast to theoretical predictions, there was little variation in cofoundress relatedness, and relatedness either did not predict skew or was negatively correlated with it; the dominant/subordinate size ratio, assumed to reflect relative fighting ability, did not predict skew; and high skew was associated with decreased aggression by the rank 2 subordinate toward the dominant. High skew was associated with increased group size. A difficulty with measuring skew in real systems is the frequent changes in group composition that commonly occur in social animals. In P. bellicosus, 61% of egg layers and an unknown number of non-egg layers were absent by the time nests were collected. The social contracts models provide an attractive general framework linking genetics, ecology, and behavior, but there have been few direct tests of their predictions. We question assumptions underlying the models and suggest directions for future research.
Modulation of Root Skewing in Arabidopsis by Apyrases and Extracellular ATP.
Yang, Xingyan; Wang, Bochu; Farris, Ben; Clark, Greg; Roux, Stanley J
2015-11-01
When plant primary roots grow along a tilted surface that is impenetrable, they can undergo a slanted deviation from the direction of gravity called skewing. Skewing is induced by touch stimuli which the roots experience as they grow along the surface. Touch stimuli also induce the release of extracellular ATP (eATP) into the plant's extracellular matrix, and two apyrases (NTPDases) in Arabidopsis, APY1 and APY2, can help regulate the concentration of eATP. The primary roots of seedlings overexpressing APY1 show less skewing than wild-type plants. Plants suppressed in their expression of APY1 show more skewing than wild-type plants. Correspondingly, chemical inhibition of apyrase activity increased skewing in mutants and wild-type roots. Exogenous application of ATP or ATPγS also increased skewing in wild-type roots, which could be blocked by co-incubation with a purinergic receptor antagonist. These results suggest a model in which gradients of eATP set up by differential touch stimuli along roots help direct skewing in roots growing along an impenetrable surface.
Log Pearson type 3 quantile estimators with regional skew information and low outlier adjustments
Griffis, V.W.; Stedinger, J.R.; Cohn, T.A.
2004-01-01
[1] The recently developed expected moments algorithm (EMA) [Cohn et al., 1997] does as well as maximum likelihood estimations at estimating log-Pearson type 3 (LP3) flood quantiles using systematic and historical flood information. Needed extensions include use of a regional skewness estimator and its precision to be consistent with Bulletin 17B. Another issue addressed by Bulletin 17B is the treatment of low outliers. A Monte Carlo study compares the performance of Bulletin 17B using the entire sample with and without regional skew with estimators that use regional skew and censor low outliers, including an extended EMA estimator, the conditional probability adjustment (CPA) from Bulletin 17B, and an estimator that uses probability plot regression (PPR) to compute substitute values for low outliers. Estimators that neglect regional skew information do much worse than estimators that use an informative regional skewness estimator. For LP3 data the low outlier rejection procedure generally results in no loss of overall accuracy, and the differences between the MSEs of the estimators that used an informative regional skew are generally modest in the skewness range of real interest. Samples contaminated to model actual flood data demonstrate that estimators which give special treatment to low outliers significantly outperform estimators that make no such adjustment.
Fieremans, Nathalie; Van Esch, Hilde; Holvoet, Maureen; Van Goethem, Gert; Devriendt, Koenraad; Rosello, Monica; Mayo, Sonia; Martinez, Francisco; Jhangiani, Shalini; Muzny, Donna M; Gibbs, Richard A; Lupski, James R; Vermeesch, Joris R; Marynen, Peter; Froyen, Guy
2016-08-01
Intellectual disability (ID) is a heterogeneous disorder with an unknown molecular etiology in many cases. Previously, X-linked ID (XLID) studies focused on males because of the hemizygous state of their X chromosome. Carrier females are generally unaffected because of the presence of a second normal allele, or inactivation of the mutant X chromosome in most of their cells (skewing). However, in female ID patients, we hypothesized that the presence of skewing of X-inactivation would be an indicator for an X chromosomal ID cause. We analyzed the X-inactivation patterns of 288 females with ID, and found that 22 (7.6%) had extreme skewing (>90%), which is significantly higher than observed in the general population (3.6%; P = 0.029). Whole-exome sequencing of 19 females with extreme skewing revealed causal variants in six females in the XLID genes DDX3X, NHS, WDR45, MECP2, and SMC1A. Interestingly, variants in genes escaping X-inactivation presumably cause both XLID and skewing of X-inactivation in three of these patients. Moreover, variants likely accounting for skewing only were detected in MED12, HDAC8, and TAF9B. All tested candidate causative variants were de novo events. Hence, extreme skewing is a good indicator for the presence of X-linked variants in female patients.
Bordered tug-of-war models are neither general nor predictive of reproductive skew.
Nonacs, Peter
2010-10-21
Models of reproductive skew assume reproductive shares are either conceded, competed over, or both. Previous mathematical evaluations found that simultaneous concessions and contests are evolutionarily unstable. Recently, Shen and Reeve (2010) challenged these conclusions and developed a series of sub-models they argued to be a unified approach to reproductive skew: the general bordered tug-of-war (BTOW). However, BTOW fails as a general model for two reasons: (1) the BTOW strategy cannot invade populations where individuals either only compete for or only concede reproductive shares and (2) contrary to Shen and Reeve's assertion, BTOW populations are easily invaded by strategies with fewer or no concessions, but competing at lower levels. The failure of BTOW as a general model has major implications for interpreting experiments on reproductive skew. A large number of studies have measured the effects of genetic relatedness and competitive ability on reproductive skew, with a great majority finding no significant correlation between variation in within-group relatedness or competitive ability and across-group differences in skew. No model of reproductive skew except one variant of the BTOW predicts such results. With the rejection of BTOW as a valid general model, it is clear that these results are contradictory to reproductive skew theory rather than supportive of it.
NASA Astrophysics Data System (ADS)
Koivisto, E.; Gordon, R.; Dyment, J.; Arkani-Hamed, J.
2006-12-01
Palaeomagnetic poles can be determined from asymmetry (skewness) of marine magnetic anomalies. Early works applying the skewness method were limited by the discovery of an apparently systematic error known as anomalous skewness (Cande 1976). Anomalous skewness can be thought of as the systematic difference between the observed skewness and the skewness predicted by a simple magnetization model with rectangular 2-D layer 2A prisms of alternating polarity separated by vertical boundaries. In the early works, anomalous skewness could be isolated for anomalies with counterparts across a mid-ocean ridge, but was much harder to estimate for anomalies with subducted counterparts, as is mostly the case in the Pacific plate. Petronotis et al. (1992) presented a solution to this problem by simultaneously estimating anomalous skewness and a best-fitting palaeomagnetic pole from skewness data from a single plate. In their approach, anomalous skewness is assumed to be identical for different crossings of the same plate and any spreading-rate dependence of anomalous skewness is neglected. Nonetheless, anomalous skewness of marine magnetic anomalies is observed to decrease with increasing spreading rate and become negligible above spreading rates of about 50 mm yr-1 (e.g. Roest et al. 1992; Dyment et al. 1994). Dyment &Arkani-Hamed (1995) proposed a model in which the magnetic structure of the oceanic lithosphere is dependent on spreading rate with parameters adjusted to fit the observed spreading- rate dependence of anomalous skewness for some key anomalies. Here we apply their model to determine a new Maastrichtian palaeomagnetic pole for the Pacific plate from skewness estimates of magnetic anomaly 32. Previously Petronotis &Gordon (1999) obtained a palaeopole assuming spreading-rate independent anomalous skewness for the same data used here. They also investigated the possible dependence of anomalous skewness on spreading rate and found it to have negligible effect on their
Skewness in large-scale structure and non-Gaussian initial conditions
NASA Technical Reports Server (NTRS)
Fry, J. N.; Scherrer, Robert J.
1994-01-01
We compute the skewness of the galaxy distribution arising from the nonlinear evolution of arbitrary non-Gaussian intial conditions to second order in perturbation theory including the effects of nonlinear biasing. The result contains a term identical to that for a Gaussian initial distribution plus terms which depend on the skewness and kurtosis of the initial conditions. The results are model dependent; we present calculations for several toy models. At late times, the leading contribution from the initial skewness decays away relative to the other terms and becomes increasingly unimportant, but the contribution from initial kurtosis, previously overlooked, has the same time dependence as the Gaussian terms. Observations of a linear dependence of the normalized skewness on the rms density fluctuation therefore do not necessarily rule out initially non-Gaussian models. We also show that with non-Gaussian initial conditions the first correction to linear theory for the mean square density fluctuation is larger than for Gaussian models.
NASA Astrophysics Data System (ADS)
Song, Shiyu; Wang, Suxin; Wang, Yongjin
2016-08-01
Motivated by the close connection between the skew Brownian motion and the random particle motion in heterogeneous media, we investigate the reflected skew Brownian motion and try to find out its relationship with the corresponding dispersion problem when there exists a reflecting boundary. Through the use of the knowledge of stochastic analysis, we provide some basic properties of reflected skew Brownian motions, including the transition density, the Laplace transform of the first passage time, and some related results. A simple method to generate the sample path is also proposed. At the end of this paper, we reveal the strong relationship between the reflected skew Brownian motion and the solute dispersion in the presence of a sharp interface and a reflecting boundary.
Fast frequency domain method to detect skew in a document image
NASA Astrophysics Data System (ADS)
Mehta, Sunita; Walia, Ekta; Dutta, Maitreyee
2015-12-01
In this paper, a new fast frequency domain method based on Discrete Wavelet Transform and Fast Fourier Transform has been implemented for the determination of the skew angle in a document image. Firstly, image size reduction is done by using two-dimensional Discrete Wavelet Transform and then skew angle is computed using Fast Fourier Transform. Skew angle error is almost negligible. The proposed method is experimented using a large number of documents having skew between -90° and +90° and results are compared with Moments with Discrete Wavelet Transform method and other commonly used existing methods. It has been determined that this method works more efficiently than the existing methods. Also, it works with typed, picture documents having different fonts and resolutions. It overcomes the drawback of the recently proposed method of Moments with Discrete Wavelet Transform that does not work with picture documents.
Asymptotic performance of the quadratic discriminant function to skewed training samples.
Adebanji, Atinuke; Asamoah-Boaheng, Michael; Osei-Tutu, Olivia
2016-01-01
This study investigates the asymptotic performance of the quadratic discriminant function (QDF) under skewed training samples. The main objective of this study is to evaluate the performance of the QDF under skewed distribution considering different sample size ratios, varying the group centroid separators and the number of variables. Three populations [Formula: see text] with increasing group centroid separator function were considered. A multivariate normal distributed data was simulated with MatLab R2009a. There was an increase in the average error rates of the sample size ratios 1:2:2 and 1:2:3 as the total sample size increased asymptotically in the skewed distribution when the centroid separator increased from 1 to 3. The QDF under the skewed distribution performed better for the sample size ratio 1:1:1 as compared to the other sampling ratios and under centroid separator [Formula: see text]. PMID:27652103
An Adaptive Method for Reducing Clock Skew in an Accumulative Z-Axis Interconnect System
NASA Technical Reports Server (NTRS)
Bolotin, Gary; Boyce, Lee
1997-01-01
This paper will present several methods for adjusting clock skew variations that occur in a n accumulative z-axis interconnect system. In such a system, delay between modules in a function of their distance from one another. Clock distribution in a high-speed system, where clock skew must be kept to a minimum, becomes more challenging when module order is variable before design.
A study on the effects of a skewed distribution on the EWMA and MA charts
NASA Astrophysics Data System (ADS)
Liew, Jeng Young; Khoo, Michael Boon Chong; Neoh, Siang Gee
2014-07-01
The control chart is the most powerful tool in statistical process control. A control chart is a graphical display used to determine the presence of assignable causes so that prompt corrective actions can be taken to remove such causes before many nonconforming products are produced. The exponentially weighted moving average (EWMA) and moving average (MA) charts are very effective in detecting small and moderate shifts in the process mean. These two charts are constructed based on the properties of the normal distribution. In many practical applications, the validity of the normality assumption is always doubted as the process distribution could be skewed. A skewed distribution can result in a higher incidence of false alarms. This is due to the inconsistencies between the spread of a skewed distribution and the normality assumption employed in setting up a control chart. This paper studies the effects of a skewed distribution on the performances of the EWMA and MA charts, in terms of the charts' false alarm rates. We compare the in-control average run length (ARL0) performance of these two charts when the underlying distributions are normal and skewed. The gamma distribution is selected to represent the skewed distribution. A Monte Carlo simulation using the Statistical Analysis System (SAS) software is carried out to compute the necessary ARL0s. The findings of this study show that the ARL0 performance of the EWMA and MA charts is substantially affected by the skewed distribution. However, the MA chart is not as robust as the EWMA chart, in terms of the ARL0, when the distribution is skewed.
Landfors, Mattias; Philip, Philge; Rydén, Patrik; Stenberg, Per
2011-01-01
Genome-wide analysis of gene expression or protein binding patterns using different array or sequencing based technologies is now routinely performed to compare different populations, such as treatment and reference groups. It is often necessary to normalize the data obtained to remove technical variation introduced in the course of conducting experimental work, but standard normalization techniques are not capable of eliminating technical bias in cases where the distribution of the truly altered variables is skewed, i.e. when a large fraction of the variables are either positively or negatively affected by the treatment. However, several experiments are likely to generate such skewed distributions, including ChIP-chip experiments for the study of chromatin, gene expression experiments for the study of apoptosis, and SNP-studies of copy number variation in normal and tumour tissues. A preliminary study using spike-in array data established that the capacity of an experiment to identify altered variables and generate unbiased estimates of the fold change decreases as the fraction of altered variables and the skewness increases. We propose the following work-flow for analyzing high-dimensional experiments with regions of altered variables: (1) Pre-process raw data using one of the standard normalization techniques. (2) Investigate if the distribution of the altered variables is skewed. (3) If the distribution is not believed to be skewed, no additional normalization is needed. Otherwise, re-normalize the data using a novel HMM-assisted normalization procedure. (4) Perform downstream analysis. Here, ChIP-chip data and simulated data were used to evaluate the performance of the work-flow. It was found that skewed distributions can be detected by using the novel DSE-test (Detection of Skewed Experiments). Furthermore, applying the HMM-assisted normalization to experiments where the distribution of the truly altered variables is skewed results in considerably higher
NASA Technical Reports Server (NTRS)
Majumdar, A. K.
1979-01-01
Expressions are derived for higher-order skewness and excess coefficients using central moments and cumulants up to 8th order. These coefficients are then calculated for three probability distributions: (1) Log-normal, (2) Rice-Nakagami, and (3) Gamma distributions. Curves are given to shown the variation of skewness with excess coefficients for these distributions. These curves are independent of the particular distribution parameters. This method is useful for studying fluctuating phenomena, which obey non-Gaussian statistics.
2014-01-01
Background In insect societies, intracolonial genetic variation is predicted to affect both colony efficiency and reproductive skew. However, because the effects of genetic variation on these two colony characteristics have been tested independently, it remains unclear whether they are affected by genetic variation independently or in a related manner. Here we test the effect of genetic variation on colony efficiency and reproductive skew in a rhinotermitid termite, Reticulitermes speratus, a species in which female-female pairs can facultatively found colonies. We established colonies using two types of female-female pairs: colonies founded by sisters (i.e., sister-pair colonies) and those founded by females from different colonies (i.e., unrelated-pair colonies). Colony growth and reproductive skew were then compared between the two types of incipient colonies. Results At 15 months after colony foundation, unrelated-pair colonies were larger than sister-pair colonies, although the caste ratio between workers and nymphs, which were alternatively differentiated from young larvae, did not differ significantly. Microsatellite DNA analyses of both founders and their parthenogenetically produced offspring indicated that, in both sister-pair and unrelated-pair colonies, there was no significant skew in the production of eggs, larvae, workers and soldiers. Nymph production, however, was significantly more skewed in the sister-pair colonies than in unrelated-pair colonies. Because nymphs can develop into winged adults (alates) or nymphoid reproductives, they have a higher chance of direct reproduction than workers in this species. Conclusions Our results support the idea that higher genetic variation among colony members could provide an increase in colony productivity, as shown in hymenopteran social insects. Moreover, this study suggests that low genetic variation (high relatedness) between founding females increases reproductive skew via one female preferentially
Static performance investigation of a skewed-throat multiaxis thrust-vectoring nozzle concept
NASA Technical Reports Server (NTRS)
Wing, David J.
1994-01-01
The static performance of a jet exhaust nozzle which achieves multiaxis thrust vectoring by physically skewing the geometric throat has been characterized in the static test facility of the 16-Foot Transonic Tunnel at NASA Langley Research Center. The nozzle has an asymmetric internal geometry defined by four surfaces: a convergent-divergent upper surface with its ridge perpendicular to the nozzle centerline, a convergent-divergent lower surface with its ridge skewed relative to the nozzle centerline, an outwardly deflected sidewall, and a straight sidewall. The primary goal of the concept is to provide efficient yaw thrust vectoring by forcing the sonic plane (nozzle throat) to form at a yaw angle defined by the skewed ridge of the lower surface contour. A secondary goal is to provide multiaxis thrust vectoring by combining the skewed-throat yaw-vectoring concept with upper and lower pitch flap deflections. The geometric parameters varied in this investigation included lower surface ridge skew angle, nozzle expansion ratio (divergence angle), aspect ratio, pitch flap deflection angle, and sidewall deflection angle. Nozzle pressure ratio was varied from 2 to a high of 11.5 for some configurations. The results of the investigation indicate that efficient, substantial multiaxis thrust vectoring was achieved by the skewed-throat nozzle concept. However, certain control surface deflections destabilized the internal flow field, which resulted in substantial shifts in the position and orientation of the sonic plane and had an adverse effect on thrust-vectoring and weight flow characteristics. By increasing the expansion ratio, the location of the sonic plane was stabilized. The asymmetric design resulted in interdependent pitch and yaw thrust vectoring as well as nonzero thrust-vector angles with undeflected control surfaces. By skewing the ridges of both the upper and lower surface contours, the interdependency between pitch and yaw thrust vectoring may be eliminated
1. WESTERN VIEW OF BRIDGE PLAZA, SHOWING MEMORIAL BRIDGE AT ...
1. WESTERN VIEW OF BRIDGE PLAZA, SHOWING MEMORIAL BRIDGE AT LEFT AND THE ROCK CREEK AND POTOMAC PARKWAY RAMP AT RIGHT. VIEW TAKEN FROM THE REAR OF THE LINCOLN MEMORIAL. - Arlington Memorial Bridge, Watergate & Bridge Plaza, Adjacent to Arlington Memorial Bridge & Lincoln Memorial, Washington, District of Columbia, DC
LOOKING WNW, CHEVROLET AVENUE BRIDGE CROSSING FLINT RIVER. BRIDGE CONNECTED ...
LOOKING WNW, CHEVROLET AVENUE BRIDGE CROSSING FLINT RIVER. BRIDGE CONNECTED NORTH AND SOUTH PORTIONS OF FACTORY COMPLEX. DANIEL LUTEN DESIGNED THE BRIDGE, AND ILLINOIS BRIDGE COMPANY BUILT IT IN 1918. THE BRIDGE WAS THE SITE OF THE BATTLE OF RUNNING BULLS IN THE 1936-1937 GM SIT DOWN STRIKE. - Delphi Flint West, 300 Chevrolet Avenue, Flint, Genesee County, MI
A novel bridge scour monitoring and prediction system
NASA Astrophysics Data System (ADS)
Valyrakis, Manousos; Michalis, Panagiotis; Zhang, Hanqing
2015-04-01
Earth's surface is continuously shaped due to the action of geophysical flows. Erosion due to the flow of water in river systems has been identified as a key problem in preserving ecological health but also a threat to our built environment and critical infrastructure, worldwide. As an example, it has been estimated that a major reason for bridge failure is due to scour. Even though the flow past bridge piers has been investigated both experimentally and numerically, and the mechanisms of scouring are relatively understood, there still lacks a tool that can offer fast and reliable predictions. Most of the existing formulas for prediction of bridge pier scour depth are empirical in nature, based on a limited range of data or for piers of specific shape. In this work, the use of a novel methodology is proposed for the prediction of bridge scour. Specifically, the use of an Adaptive Neuro-Fuzzy Inference System (ANFIS) is proposed to estimate the scour depth around bridge piers. In particular, various complexity architectures are sequentially built, in order to identify the optimal for scour depth predictions, using appropriate training and validation subsets obtained from the USGS database (and pre-processed to remove incomplete records). The model has five variables, namely the effective pier width (b), the approach velocity (v), the approach depth (y), the mean grain diameter (D50) and the skew to flow. Simulations are conducted with data groups (bed material type, pier type and shape) and different number of input variables, to produce reduced complexity and easily interpretable models. Analysis and comparison of the results indicate that the developed ANFIS model has high accuracy and outstanding generalization ability for prediction of scour parameters. The effective pier width (as opposed to skew to flow) is amongst the most relevant input parameters for the estimation. Training of the system to new bridge geometries and flow conditions can be achieved by
de Kloet, H J; van Pelt, A W
1996-11-01
An adhesive or resin-bonded bridge is a tooth saving construction for the replacement of a lost tooth, especially when the abutment teeth are relatively sound. In this article an overview is presented of the different types of resin-bonded bridges, their advantages and disadvantages and their indications. The direct methods are very suited for the immediate replacement of a lost anterior tooth. The all composite adhesive bridge has a survival rate that is surprisingly good.
Modeling absolute differences in life expectancy with a censored skew-normal regression approach
Clough-Gorr, Kerri; Zwahlen, Marcel
2015-01-01
Parameter estimates from commonly used multivariable parametric survival regression models do not directly quantify differences in years of life expectancy. Gaussian linear regression models give results in terms of absolute mean differences, but are not appropriate in modeling life expectancy, because in many situations time to death has a negative skewed distribution. A regression approach using a skew-normal distribution would be an alternative to parametric survival models in the modeling of life expectancy, because parameter estimates can be interpreted in terms of survival time differences while allowing for skewness of the distribution. In this paper we show how to use the skew-normal regression so that censored and left-truncated observations are accounted for. With this we model differences in life expectancy using data from the Swiss National Cohort Study and from official life expectancy estimates and compare the results with those derived from commonly used survival regression models. We conclude that a censored skew-normal survival regression approach for left-truncated observations can be used to model differences in life expectancy across covariates of interest. PMID:26339544
Eggert, Anne-Katrin; Otte, Tobias; Müller, Josef K
2008-01-01
Proximate mechanisms underlying reproductive skew are obscure in many animals that breed communally. Here, we address causes of reproductive skew in brood-parasitic associations of burying beetles (Nicrophorus vespilloides). Male and female burying beetles feed and defend their larvae on buried carcasses. When several females locate the same small carcass, they engage in violent physical altercations. The subordinate then acts as an intraspecific brood parasite, laying eggs, but not providing care. The dominant female largely monopolizes access to the carcass; she alone provides parental care and her share of the brood is much larger than the subordinate's. On larger carcasses, subordinates have greater access to the carcass than on small ones, and reproductive skew is reduced. Differential fecundity, ovicide and larvicide have been suggested as causes of skew on small carcasses. Here, we report the results of the experiments pertaining to the first two of these potential mechanisms. Ovicide did not significantly contribute to reproductive skew on small carcasses, but differential fecundity did. Fecundity differences were due to dominance status, not body size per se. Fecundity differences disappeared when supplemental food was available, suggesting that reduced access to the carcass limits fecundity by causing nutritional deficiencies. Supplemental food prevented such nutritional deficiencies and allowed subordinates to produce as many eggs as dominants. Apparently, aggressive behaviour by dominants functions in the context of reproductive competition, limiting subordinate reproduction by preventing food intake on the carcass. PMID:18647719
Semiconductor bridge (SCB) detonator
Bickes, Jr., Robert W.; Grubelich, Mark C.
1999-01-01
The present invention is a low-energy detonator for high-density secondary-explosive materials initiated by a semiconductor bridge igniter that comprises a pair of electrically conductive lands connected by a semiconductor bridge. The semiconductor bridge is in operational or direct contact with the explosive material, whereby current flowing through the semiconductor bridge causes initiation of the explosive material. Header wires connected to the electrically-conductive lands and electrical feed-throughs of the header posts of explosive devices, are substantially coaxial to the direction of current flow through the SCB, i.e., substantially coaxial to the SCB length.
Semiconductor bridge (SCB) detonator
Bickes, R.W. Jr.; Grubelich, M.C.
1999-01-19
The present invention is a low-energy detonator for high-density secondary-explosive materials initiated by a semiconductor bridge (SCB) igniter that comprises a pair of electrically conductive lands connected by a semiconductor bridge. The semiconductor bridge is in operational or direct contact with the explosive material, whereby current flowing through the semiconductor bridge causes initiation of the explosive material. Header wires connected to the electrically-conductive lands and electrical feed-throughs of the header posts of explosive devices, are substantially coaxial to the direction of current flow through the SCB, i.e., substantially coaxial to the SCB length. 3 figs.
11. Southern bridge abutment and arches, taken from old bridge ...
11. Southern bridge abutment and arches, taken from old bridge abutment looking south. - Presumpscot Falls Bridge, Spanning Presumptscot River at Allen Avenue extension, 0.75 mile west of U.S. Interstate 95, Falmouth, Cumberland County, ME
GOETHALS BRIDGE FROM NORTH SIDE OVER ARTHUR KILL. RAILROAD BRIDGE ...
GOETHALS BRIDGE FROM NORTH SIDE OVER ARTHUR KILL. RAILROAD BRIDGE IN FOREGROUND - Goethals Bridge, Spanning Arthur Kill from New Jersey to Staten Island, Staten Island (subdivision), Richmond County, NY
4. View of Clark Fork Vehicle Bridge facing northeast. Bridge ...
4. View of Clark Fork Vehicle Bridge facing northeast. Bridge from south shoreof Clark Fork River showing 4 spans. - Clark Fork Vehicle Bridge, Spanning Clark Fork River, serves Highway 200, Clark Fork, Bonner County, ID
2. View of Clark Fork Vehicle Bridge facing northeast. Bridge ...
2. View of Clark Fork Vehicle Bridge facing northeast. Bridge from south shore of Clark Fork River showing 4 1/2 spans. - Clark Fork Vehicle Bridge, Spanning Clark Fork River, serves Highway 200, Clark Fork, Bonner County, ID
7. View of Clark Fork Vehicle Bridge facing northwest. Bridge ...
7. View of Clark Fork Vehicle Bridge facing northwest. Bridge from south shore of Clark Fork River showing 4 1/2 spans. - Clark Fork Vehicle Bridge, Spanning Clark Fork River, serves Highway 200, Clark Fork, Bonner County, ID
3. View of Clark Fork Vehicle Bridge facing southwest. Bridge ...
3. View of Clark Fork Vehicle Bridge facing southwest. Bridge from north shore of Clark Fork River. - Clark Fork Vehicle Bridge, Spanning Clark Fork River, serves Highway 200, Clark Fork, Bonner County, ID
Plans: Poop Deck, Boat Deck, Housetop, Bridge Deck, Upper Bridge ...
Plans: Poop Deck, Boat Deck, Housetop, Bridge Deck, Upper Bridge Deck, Navigating Bridge, Forecastle Deck, Upper Deck, Second Deck and Hold - Saugatuck, James River Reserve Fleet, Newport News, Newport News, VA
APPROACH BRIDGE PORTION OF VALVE TOWER FOOT BRIDGE, AS SEEN ...
APPROACH BRIDGE PORTION OF VALVE TOWER FOOT BRIDGE, AS SEEN FROM ENTRY. VIEW FACING NORTHWEST - Schofield Barracks Military Reservation, Ku Tree Reservoir, Valve Tower Foot Bridge, Kalakoa Stream, East Range, Wahiawa, Honolulu County, HI
APPROACH BRIDGE PORTION OF VALVE TOWER FOOT BRIDGE, AS SEEN ...
APPROACH BRIDGE PORTION OF VALVE TOWER FOOT BRIDGE, AS SEEN FROM BELOW, SHOWING VALVE TOWER TO RIGHT. VIEW FACING NORTH - Schofield Barracks Military Reservation, Ku Tree Reservoir, Valve Tower Foot Bridge, Kalakoa Stream, East Range, Wahiawa, Honolulu County, HI
Julià, Olga; Vidal-Mas, Jaume; Panikov, Nicolai S; Vives-Rego, Josep
2010-01-01
We report a skew-Laplace statistical analysis of both flow cytometry scatters and cell size from microbial strains primarily grown in batch cultures, others in chemostat cultures and bacterial aquatic populations. Cytometry scatters best fit the skew-Laplace distribution while cell size as assessed by an electronic particle analyzer exhibited a moderate fitting. Unlike the cultures, the aquatic bacterial communities clearly do not fit to a skew-Laplace distribution. Due to its versatile nature, the skew-Laplace distribution approach offers an easy, efficient, and powerful tool for distribution of frequency analysis in tandem with the flow cytometric cell sorting.
Julià, Olga; Vidal-Mas, Jaume; Panikov, Nicolai S.; Vives-Rego, Josep
2010-01-01
We report a skew-Laplace statistical analysis of both flow cytometry scatters and cell size from microbial strains primarily grown in batch cultures, others in chemostat cultures and bacterial aquatic populations. Cytometry scatters best fit the skew-Laplace distribution while cell size as assessed by an electronic particle analyzer exhibited a moderate fitting. Unlike the cultures, the aquatic bacterial communities clearly do not fit to a skew-Laplace distribution. Due to its versatile nature, the skew-Laplace distribution approach offers an easy, efficient, and powerful tool for distribution of frequency analysis in tandem with the flow cytometric cell sorting. PMID:20592754
NASA Astrophysics Data System (ADS)
Kim, Tae-Woo; Chang, Jung-Hwan
2013-08-01
This paper suggests an effective step-skew method to reduce the cogging torque of a surface-mounted permanent magnet synchronous motor (SPMSM). The main concept of the proposed method is to adjust each step length by considering the non-uniform air gap flux density distribution in the axial direction. The results show that the proposed step-skew method reduces the net cogging torque compared with the conventional step-skew method and is more effective for smaller stacking lengths and larger skew steps.
Watermann, J.; McNamara, A.G. ); Sofko, G.J.; Koehler, J.A. )
1989-06-01
Some 7,700 radio aurora spectra obtained from a six link 50-MHz CW radar network set up on the Canadian prairies were analyzed with respect to the distributions of mean Doppler shift, spectral width and skewness. A comparison with recently published SABRE results obtained at 153 MHz shows substantial differences in the distributions which are probably due to different experimental and geophysical conditions. The spectra are mostly broad with mean Doppler shifts close to zero (type II spectra). The typical groupings of type I and type III spectra are clearly identified. All types appear to be in general much more symmetric than those recorded with SABRE, and the skewness is only weakly dependent on the sign of the mean Doppler shift. Its distribution peaks near zero and shows a weak positive correlation with the type II Doppler shifts while the mostly positive type I Doppler shifts are slightly negatively correlated with the skewness.
A Berger-type theorem for metric connections with skew-symmetric torsion
NASA Astrophysics Data System (ADS)
Reggiani, Silvio
2013-03-01
We prove a Berger-type theorem which asserts that if the orthogonal subgroup generated by the torsion tensor (pulled back to a point by parallel transport) of a metric connection with skew-symmetric torsion is not transitive on the sphere, then the space must be locally isometric to a Lie group with a bi-invariant metric or its symmetric dual (we assume the space to be locally irreducible). We also prove that a (simple) Lie group with a bi-invariant metric admits only two flat metric connections with skew-symmetric torsion: the two flat canonical connections. In particular, we get a refinement of a well-known theorem of Cartan and Schouten. Finally, we show that the holonomy group of a metric connection with skew-symmetric torsion on these spaces generically coincides with the Riemannian holonomy.
Modeling the effects of wave skewness and beach cusps on littoral sand transport
Haas, K.A.; Check, L.A.; Hanes, D.M.
2008-01-01
A process-based numerical modeling system is utilized for predicting littoral sand transport. The intent is to examine conditions slightly more complex than linear waves impinging upon a plane beach. Two factors that we examine are wave skewness and longshore varying bathymetry. An empirical model is used for calculating the skewed bottom wave orbital velocity. The advection of sediment due to the skewed wave velocity is larger and in the direction of the waves, opposite to the results with sinusoidal wave velocities, due to the increase in the bottom shear stress under the wave crests. The model system is also applied to bathymetry containing beach cusps. When the wave field has relatively weak longshore wave power, the currents and the littoral transport exhibit significant longshore variability, thereby altering the overall mean littoral transport.
Perceived quality of wood images influenced by the skewness of image histogram
NASA Astrophysics Data System (ADS)
Katsura, Shigehito; Mizokami, Yoko; Yaguchi, Hirohisa
2015-08-01
The shape of image luminance histograms is related to material perception. We investigated how the luminance histogram contributed to improvements in the perceived quality of wood images by examining various natural wood and adhesive vinyl sheets with printed wood grain. In the first experiment, we visually evaluated the perceived quality of wood samples. In addition, we measured the colorimetric parameters of the wood samples and calculated statistics of image luminance. The relationship between visual evaluation scores and image statistics suggested that skewness and kurtosis affected the perceived quality of wood. In the second experiment, we evaluated the perceived quality of wood images with altered luminance skewness and kurtosis using a paired comparison method. Our result suggests that wood images are more realistic if the skewness of the luminance histogram is slightly negative.
Gaudin-type models, non-skew-symmetric classical r-matrices and nested Bethe ansatz
NASA Astrophysics Data System (ADS)
Skrypnyk, T.
2015-02-01
We consider quantum integrable systems associated with the Lie algebra gl (n) and Cartan-invariant non-dynamical non-skew-symmetric classical r-matrices. We describe the sub-class of Cartan-invariant non-skew-symmetric r-matrices for which exists the standard procedure of the nested Bethe ansatz associated with the chain of embeddings gl (n) ⊃ gl (n - 1) ⊃ gl (n - 2) ⊃ ⋯ ⊃ gl (1). We diagonalize the corresponding quantum integrable systems by its means. We illustrate the obtained results by the examples of the generalized Gaudin systems with and without external magnetic field associated with three classes of non-dynamical non-skew-symmetric classical r-matrices.
Skewness in CMB temperature fluctuations from curved cosmic (super-)strings
Yamauchi, Daisuke; Sendouda, Yuuiti; Yoo, Chul-Moon; Naruko, Atsushi; Sasaki, Misao; Takahashi, Keitaro E-mail: sendouda@yukawa.kyoto-u.ac.jp E-mail: keitaro@a.phys.nagoya-u.ac.jp E-mail: misao@yukawa.kyoto-u.ac.jp
2010-05-01
We compute the one-point probability distribution function of small-angle cosmic microwave background temperature fluctuations due to curved cosmic (super-)strings with a simple model of string network by performing Monte Carlo simulations. Taking into account of the correlation between the curvature and the velocity of string segments, there appear non-Gaussian features, specifically non-Gaussian tails and a skewness, in the one-point pdf. The obtained sample skewness for the conventional field-theoretic cosmic strings is g{sub 1} ≈ −0.14, which is consistent with the result reported by Fraisse et al. We also discuss the dependence of the pdf on the intercommuting probability. We find that the standard deviation of the Gaussian part increases and non-Gaussian features are suppressed as the intercommuting probability decreases. For sufficiently small intercommuting probability, the skewness is given by ∼< (a few) × 10{sup −2}.
The log-dynamic brain: how skewed distributions affect network operations
Buzsáki, György; Mizuseki, Kenji
2014-01-01
We often assume that the variables of functional and structural brain parameters — such as synaptic weights, the firing rates of individual neurons, the synchronous discharge of neural populations, the number of synaptic contacts between neurons and the size of dendritic boutons — have a bell-shaped distribution. However, at many physiological and anatomical levels in the brain, the distribution of numerous parameters is in fact strongly skewed with a heavy tail, suggesting that skewed (typically lognormal) distributions are fundamental to structural and functional brain organization. This insight not only has implications for how we should collect and analyse data, it may also help us to understand how the different levels of skewed distributions — from synapses to cognition — are related to each other. PMID:24569488
NASA Astrophysics Data System (ADS)
Fan, Ya-Jing; Cao, Huai-Xin; Meng, Hui-Xian; Chen, Liang
2016-09-01
The uncertainty principle in quantum mechanics is a fundamental relation with different forms, including Heisenberg's uncertainty relation and Schrödinger's uncertainty relation. In this paper, we prove a Schrödinger-type uncertainty relation in terms of generalized metric adjusted skew information and correlation measure by using operator monotone functions, which reads, U_ρ ^{(g,f)}(A)U_ρ ^{(g,f)}(B)≥ f(0)^2l/k| {Corr}_ρ ^{s(g,f)}(A,B)| ^2 for some operator monotone functions f and g, all n-dimensional observables A, B and a non-singular density matrix ρ . As applications, we derive some new uncertainty relations for Wigner-Yanase skew information and Wigner-Yanase-Dyson skew information.
NASA Astrophysics Data System (ADS)
Skrypnyk, T.
2010-08-01
Using non-skew-symmetric classical r-matrices r12(u,v) with spectral parameters, we generalize Fuchsian systems and Schlesinger equations (isomonodromy equations) viewing the last as the nonautonomous Hamiltonian equations corresponding to the generalized Gaudin Hamiltonians. Quantizing these systems we construct generalization of Knizhnik-Zamolodchikov equations corresponding to the non-skew-symmetric classical r-matrices r12(u,v) with spectral parameters. In the case of an ordinary skew-symmetric classical r-matrix r12(u-v) depending on the difference of the spectral parameters, we reobtain, as special partial cases, a standard generalization of Fuchsian systems, Schlesinger, and Knizhnik-Zamolodchikov equations.
Zheng, Shimin; Rao, Uma; Bartolucci, Alfred A.; Singh, Karan P.
2011-01-01
Bartolucci et al.(2003) extended the distribution assumption from the normal (Lyles et al., 2000) to the elliptical contoured distribution (ECD) for random regression models used in analysis of longitudinal data accounting for both undetectable values and informative drop-outs. In this paper, the random regression models are constructed on the multivariate skew ECD. A real data set is used to illustrate that the skew ECDs can fit some unimodal continuous data better than the Gaussian distributions or more general continuous symmetric distributions when the symmetric distribution assumption is violated. Also, a simulation study is done for illustrating the model fitness from a variety of skew ECDs. The software we used is SAS/STAT, V. 9.13. PMID:21637734
Separating the effects of mutation and selection in producing DNA skew in bacterial chromosomes
Morton, Richard A; Morton, Brian R
2007-01-01
Background Many bacterial chromosomes display nucleotide asymmetry, or skew, between the leading and lagging strands of replication. Mutational differences between these strands result in an overall pattern of skew that is centered about the origin of replication. Such a pattern could also arise from selection coupled with a bias for genes coded on the leading strand. The relative contributions of selection and mutation in producing compositional skew are largely unknown. Results We describe a model to quantify the contribution of mutational differences between the leading and lagging strands in producing replication-induced skew. When the origin and terminus of replication are known, the model can be used to estimate the relative accumulation of G over C and of A over T on the leading strand due to replication effects in a chromosome with bidirectional replication arms. The model may also be implemented in a maximum likelihood framework to estimate the locations of origin and terminus. We find that our estimations for the origin and terminus agree very well with the location of genes that are thought to be associated with the replication origin. This indicates that our model provides an accurate, objective method of determining the replication arms and also provides support for the hypothesis that these genes represent an ancestral cluster of origin-associated genes. Conclusion The model has several advantages over other methods of analyzing genome skew. First, it quantifies the role of mutation in generating skew so that its effect on composition, for example codon bias, can be assessed. Second, it provides an objective method for locating origin and terminus, one that is based on chromosome-wide accumulation of leading vs lagging strand nucleotide differences. Finally, the model has the potential to be utilized in a maximum likelihood framework in order to analyze the effect of chromosome rearrangements on nucleotide composition. PMID:17935620
Atypical AT Skew in Firmicute Genomes Results from Selection and Not from Mutation
Charneski, Catherine A.; Honti, Frank; Bryant, Josephine M.
2011-01-01
The second parity rule states that, if there is no bias in mutation or selection, then within each strand of DNA complementary bases are present at approximately equal frequencies. In bacteria, however, there is commonly an excess of G (over C) and, to a lesser extent, T (over A) in the replicatory leading strand. The low G+C Firmicutes, such as Staphylococcus aureus, are unusual in displaying an excess of A over T on the leading strand. As mutation has been established as a major force in the generation of such skews across various bacterial taxa, this anomaly has been assumed to reflect unusual mutation biases in Firmicute genomes. Here we show that this is not the case and that mutation bias does not explain the atypical AT skew seen in S. aureus. First, recently arisen intergenic SNPs predict the classical replication-derived equilibrium enrichment of T relative to A, contrary to what is observed. Second, sites predicted to be under weak purifying selection display only weak AT skew. Third, AT skew is primarily associated with largely non-synonymous first and second codon sites and is seen with respect to their sense direction, not which replicating strand they lie on. The atypical AT skew we show to be a consequence of the strong bias for genes to be co-oriented with the replicating fork, coupled with the selective avoidance of both stop codons and costly amino acids, which tend to have T-rich codons. That intergenic sequence has more A than T, while at mutational equilibrium a preponderance of T is expected, points to a possible further unresolved selective source of skew. PMID:21935355
Sulphite Railroad Bridge1896, Title Sheet Sulphite Railroad Bridge, Former ...
Sulphite Railroad Bridge-1896, Title Sheet - Sulphite Railroad Bridge, Former Boston & Maine Railroad (originally Tilton & Franklin Railroad) spanning Winnipesautee River, Franklin, Merrimack County, NH
LODGEPOLE BRIDGE, FACING NORTHWEST Generals Highway, Lodge Pole Bridge, ...
LODGEPOLE BRIDGE, FACING NORTHWEST - Generals Highway, Lodge Pole Bridge, Spanning Marble Fork of Kaweah River, approximately 21 miles northwest of Ash Mountain Entrance, Three Rivers, Tulare County, CA
LODGEPOLE BRIDGE, FACING SOUTHEAST Generals Highway, Lodge Pole Bridge, ...
LODGEPOLE BRIDGE, FACING SOUTHEAST - Generals Highway, Lodge Pole Bridge, Spanning Marble Fork of Kaweah River, approximately 21 miles northwest of Ash Mountain Entrance, Three Rivers, Tulare County, CA
NASA Technical Reports Server (NTRS)
White, D. R.
1968-01-01
Prototype precision bolometer calibration bridge is manually balanced device for indicating dc bias and balance with either dc or ac power. An external galvanometer is used with the bridge for null indication, and the circuitry monitors voltage and current simultaneously without adapters in testing 100 and 200 ohm thin film bolometers.
Wessendorf, Kurt O.
2001-01-01
An active bridge oscillator is formed from a differential amplifier where positive feedback is a function of the impedance of one of the gain elements and a relatively low value common emitter resistance. This use of the nonlinear transistor parameter h stabilizes the output and eliminates the need for ALC circuits common to other bridge oscillators.
Virtual Bridge Design Challenge
ERIC Educational Resources Information Center
Mitts, Charles R.
2013-01-01
This design/problem-solving activity challenges students to design a replacement bridge for one that has been designated as either structurally deficient or functionally obsolete. The Aycock MS Technology/STEM Magnet Program Virtual Bridge Design Challenge is an authentic introduction to the engineering design process. It is a socially relevant…
Modelling a Suspension Bridge.
ERIC Educational Resources Information Center
Rawlins, Phil
1991-01-01
The quadratic function can be modeled in real life by a suspension bridge that supports a uniform weight. This activity uses concrete models and computer generated graphs to discover the mathematical model of the shape of the main cable of a suspension bridge. (MDH)
Rhiel, G Steven
2010-02-01
In 2007, Rhiel presented a technique to estimate the coefficient of variation from the range when sampling from skewed distributions. To provide an unbiased estimate, a correction factor (a(n)) for the mean was included. Numerical correction factors for a number of skewed distributions were provided. In a follow-up paper, he provided a proof he claimed showed the correction factor was independent of the mean and standard deviation, making the factors useful as these parameters vary; however, that proof did not establish independence. Herein is a proof which establishes the independence.
Mixed-derivative skewness for high Prandtl and Reynolds numbers in homogeneous isotropic turbulence
NASA Astrophysics Data System (ADS)
Briard, Antoine; Gomez, Thomas
2016-08-01
The mixed-derivative skewness Suθ of a passive scalar field in high Reynolds and Prandtl numbers decaying homogeneous isotropic turbulence is studied numerically using eddy-damped quasi-normal Markovian closure, for Reλ ≥ 103 up to Pr = 105. A convergence of Suθ for Pr ≥ 103 is observed for any high enough Reynolds number. This asymptotic high Pr regime can be interpreted as a saturation of the mixing properties of the flow at small scales. The decay of the derivative skewnesses from high to low Reynolds numbers and the influence of large scales initial conditions are investigated as well.
Multivariate skew- t approach to the design of accumulation risk scenarios for the flooding hazard
NASA Astrophysics Data System (ADS)
Ghizzoni, Tatiana; Roth, Giorgio; Rudari, Roberto
2010-10-01
The multivariate version of the skew- t distribution provides a powerful analytical description of the joint behavior of multivariate processes. It enjoys valuable properties: from the aptitude to model skewed as well as leptokurtic datasets to the availability of moments and likelihood analytical expressions. Moreover, it offers a wide range of extremal dependence strength, allowing for upper and lower tail dependence. The idea underneath this work is to employ the multivariate skew- t distribution to provide an estimation of the joint probability of flood events in a multi-site multi-basin approach. This constitutes the basis for the design and evaluation of flood hazard scenarios for large areas in terms of their intensity, extension and frequency, i.e. those information required by civil protection agencies to put in action mitigation strategies and by insurance companies to price the flooding risk and to evaluate portfolios. Performances of the skew- t distribution and the corresponding t copula function, introduced to represent the state of the art for multivariate simulations, are discussed with reference to the Tanaro Basin, North-western Italy. To enhance the characteristics of the correlation structure, three nested and non-nested gauging stations are selected with contributing areas from 1500 to 8000 km 2. A dataset of 76 trivariate flood events is extracted from a mean daily discharges database available for the time period from January 1995 to December 2003. Applications include the generation of multivariate skew- t and t copula samples and models' comparison through the principle of minimum cross-entropy, here revised for the application to multivariate samples. Copula and skew- t based scenario return period estimations are provided for the November 1994 flood event, i.e. the worst on record in the 1801-2001 period. Results are encouraging: the skew- t distribution seems able to describe the joint behavior, being close to the observations. Marginal
Alternating skew deviation in association with anti-glutamic acid decarboxylase antibodies
Farooq, Asim V.; Soin, Ketki; Moss, Heather E.
2015-01-01
The presence of an elevated anti-glutamic acid decarboxylase (GAD) antibody level has been associated with a number of eye movement abnormalities, as well as other findings including cerebellar ataxia and insulin dependent diabetes mellitus. Skew deviation in association with anti-GAD antibodies has not been previously reported. Here we report a case of alternating skew deviation along with cerebellar-brainstem signs in a patient with an elevated anti-GAD antibody titer. Follow-up neurologic evaluation after treatment with intravenous immunoglobulin revealed improvement in cerebellar-brainstem signs, while ophthalmic evaluation was stable. PMID:26594078
An analytical algorithm for skew-slit imaging geometry with nonuniform attenuation correction
Huang Qiu; Zeng, Gengsheng L.
2006-04-15
The pinhole collimator is currently the collimator of choice in small animal single photon emission computed tomography (SPECT) imaging because it can provide high spatial resolution and reasonable sensitivity when the animal is placed very close to the pinhole. It is well known that if the collimator rotates around the object (e.g., a small animal) in a circular orbit to form a cone-beam imaging geometry with a planar trajectory, the acquired data are not sufficient for an exact artifact-free image reconstruction. In this paper a novel skew-slit collimator is mounted instead of the pinhole collimator in order to significantly reduce the image artifacts caused by the geometry. The skew-slit imaging geometry is a more generalized version of the pinhole imaging geometry. The multiple pinhole geometry can also be extended to the multiple-skew-slit geometry. An analytical algorithm for image reconstruction based on the tilted fan-beam inversion is developed with nonuniform attenuation compensation. Numerical simulation shows that the axial artifacts are evidently suppressed in the skew-slit images compared to the pinhole images and the attenuation correction is effective.
Using social parasitism to test reproductive skew models in a primitively eusocial wasp.
Green, Jonathan P; Cant, Michael A; Field, Jeremy
2014-08-22
Remarkable variation exists in the distribution of reproduction (skew) among members of cooperatively breeding groups, both within and between species. Reproductive skew theory has provided an important framework for understanding this variation. In the primitively eusocial Hymenoptera, two models have been routinely tested: concessions models, which assume complete control of reproduction by a dominant individual, and tug-of-war models, which assume on-going competition among group members over reproduction. Current data provide little support for either model, but uncertainty about the ability of individuals to detect genetic relatedness and difficulties in identifying traits conferring competitive ability mean that the relative importance of concessions versus tug-of-war remains unresolved. Here, we suggest that the use of social parasitism to generate meaningful variation in key social variables represents a valuable opportunity to explore the mechanisms underpinning reproductive skew within the social Hymenoptera. We present a direct test of concessions and tug-of-war models in the paper wasp Polistes dominulus by exploiting pronounced changes in relatedness and power structures that occur following replacement of the dominant by a congeneric social parasite. Comparisons of skew in parasitized and unparasitized colonies are consistent with a tug-of-war over reproduction within P. dominulus groups, but provide no evidence for reproductive concessions.
The curious anomaly of skewed judgment distributions and systematic error in the wisdom of crowds.
Nash, Ulrik W
2014-01-01
Judgment distributions are often skewed and we know little about why. This paper explains the phenomenon of skewed judgment distributions by introducing the augmented quincunx (AQ) model of sequential and probabilistic cue categorization by neurons of judges. In the process of developing inferences about true values, when neurons categorize cues better than chance, and when the particular true value is extreme compared to what is typical and anchored upon, then populations of judges form skewed judgment distributions with high probability. Moreover, the collective error made by these people can be inferred from how skewed their judgment distributions are, and in what direction they tilt. This implies not just that judgment distributions are shaped by cues, but that judgment distributions are cues themselves for the wisdom of crowds. The AQ model also predicts that judgment variance correlates positively with collective error, thereby challenging what is commonly believed about how diversity and collective intelligence relate. Data from 3053 judgment surveys about US macroeconomic variables obtained from the Federal Reserve Bank of Philadelphia and the Wall Street Journal provide strong support, and implications are discussed with reference to three central ideas on collective intelligence, these being Galton's conjecture on the distribution of judgments, Muth's rational expectations hypothesis, and Page's diversity prediction theorem. PMID:25406078
Large-scale age-dependent skewed sex ratio in a sexually dimorphic avian scavenger.
Lambertucci, Sergio A; Carrete, Martina; Donázar, José Antonio; Hiraldo, Fernando
2012-01-01
Age-dependent skewed sex ratios have been observed in bird populations, with adult males generally outnumbering females. This trend is mainly driven by higher female mortality, sometimes associated with anthropogenic factors. Despite the large amount of work on bird sex ratios, research examining the spatial stability of adult sex ratios is extremely scarce. The Andean condor (Vultur gryphus) is the only bird of prey with strong sexual dimorphism favouring males (males are 30% heavier than females). By examining data from most of its South-American range, we show that while the juvenile sex ratio is balanced, or even female-skewed, the sex ratio becomes increasing male-skewed with age, with adult males outnumbering females by >20%, and, in some cases by four times more. This result is consistent across regions and independent of the nature of field data. Reasons for this are unknown but it can be hypothesized that the progressive disappearance of females may be associated with mortality caused by anthropogenic factors. This idea is supported by the asymmetric habitat use by the two sexes, with females scavenging in more humanized areas. Whatever the cause, male-skewed adult sex ratios imply that populations of this endangered scavenger face higher risks of extinction than previously believed.
Large-Scale Age-Dependent Skewed Sex Ratio in a Sexually Dimorphic Avian Scavenger
Lambertucci, Sergio A.; Carrete, Martina; Donázar, José Antonio; Hiraldo, Fernando
2012-01-01
Age-dependent skewed sex ratios have been observed in bird populations, with adult males generally outnumbering females. This trend is mainly driven by higher female mortality, sometimes associated with anthropogenic factors. Despite the large amount of work on bird sex ratios, research examining the spatial stability of adult sex ratios is extremely scarce. The Andean condor (Vultur gryphus) is the only bird of prey with strong sexual dimorphism favouring males (males are 30% heavier than females). By examining data from most of its South-American range, we show that while the juvenile sex ratio is balanced, or even female-skewed, the sex ratio becomes increasing male-skewed with age, with adult males outnumbering females by >20%, and, in some cases by four times more. This result is consistent across regions and independent of the nature of field data. Reasons for this are unknown but it can be hypothesized that the progressive disappearance of females may be associated with mortality caused by anthropogenic factors. This idea is supported by the asymmetric habitat use by the two sexes, with females scavenging in more humanized areas. Whatever the cause, male-skewed adult sex ratios imply that populations of this endangered scavenger face higher risks of extinction than previously believed. PMID:23029488
On Some Confidence Intervals for Estimating the Mean of a Skewed Population
ERIC Educational Resources Information Center
Shi, W.; Kibria, B. M. Golam
2007-01-01
A number of methods are available in the literature to measure confidence intervals. Here, confidence intervals for estimating the population mean of a skewed distribution are considered. This note proposes two alternative confidence intervals, namely, Median t and Mad t, which are simple adjustments to the Student's t confidence interval. In…
Tan, Kun; An, Lei; Miao, Kai; Ren, Likun; Hou, Zhuocheng; Tao, Li; Zhang, Zhenni; Wang, Xiaodong; Xia, Wei; Liu, Jinghao; Wang, Zhuqing; Xi, Guangyin; Gao, Shuai; Sui, Linlin; Zhu, De-Sheng; Wang, Shumin; Wu, Zhonghong; Bach, Ingolf; Chen, Dong-bao; Tian, Jianhui
2016-01-01
Dynamic epigenetic reprogramming occurs during normal embryonic development at the preimplantation stage. Erroneous epigenetic modifications due to environmental perturbations such as manipulation and culture of embryos during in vitro fertilization (IVF) are linked to various short- or long-term consequences. Among these, the skewed sex ratio, an indicator of reproductive hazards, was reported in bovine and porcine embryos and even human IVF newborns. However, since the first case of sex skewing reported in 1991, the underlying mechanisms remain unclear. We reported herein that sex ratio is skewed in mouse IVF offspring, and this was a result of female-biased peri-implantation developmental defects that were originated from impaired imprinted X chromosome inactivation (iXCI) through reduced ring finger protein 12 (Rnf12)/X-inactive specific transcript (Xist) expression. Compensation of impaired iXCI by overexpression of Rnf12 to up-regulate Xist significantly rescued female-biased developmental defects and corrected sex ratio in IVF offspring. Moreover, supplementation of an epigenetic modulator retinoic acid in embryo culture medium up-regulated Rnf12/Xist expression, improved iXCI, and successfully redeemed the skewed sex ratio to nearly 50% in mouse IVF offspring. Thus, our data show that iXCI is one of the major epigenetic barriers for the developmental competence of female embryos during preimplantation stage, and targeting erroneous epigenetic modifications may provide a potential approach for preventing IVF-associated complications. PMID:26951653
Skewing (n +1) Tensor Indices where the Index Range is n
ERIC Educational Resources Information Center
Agacy, R. L.
2005-01-01
It is known that any totally skew quantity with (n + 1) indices, each of which ranges over n values, vanishes identically. The aim of this short note is to show that this is equivalent to the simple fact that any (n + 1) vectors in an n-dimensional vector space are linearly dependent.
A Monte Carlo Study of Skewed Theta Distributions on DIF Indices.
ERIC Educational Resources Information Center
Monaco, Malina
The effects of skewed theta distributions on indices of differential item functioning (DIF) were studied, comparing Mantel Haenszel (N. Mantel and W. Haenszel, 1959) and DFIT (N. S. Raju, W. J. van der Linden, and P. F. Fleer) (noncompensatory DIF). The significance of the study is that in educational and psychological data, the distributions one…
Bayesian Comparison of GARCH Processes with Skewness Mechanism in Conditional Distributions
NASA Astrophysics Data System (ADS)
Pipien, M.
2006-11-01
The main goal of this paper is an application of Bayesian model comparison, based on the posterior probabilities and posterior odds ratios, in testing the explanatory power of a set of competing GARCH (Generalized Autoregressive Conditionally Heteroscedastic) specifications, all with asymmetric and heavy tailed conditional distributions. In building competing volatility models we consider, as an initial specification, conditionally Student-t GARCH process with unknown degrees of freedom parameter. By introducing skewness into Student-t family and incorporating the resulting class as a conditional distribution we generated various GARCH models, which compete in explaining possible asymmetry of both conditional and unconditional distribution of financial data. In order to make Student-t family skewed we consider various alternative mechanisms recently proposed in the literature. In particular, we apply the hidden truncation mechanism, an approach based on the inverse scale factors in the positive and the negative orthant, order statistics concept, Beta distribution transformation and Bernstein density transformation. Additionally, we consider GARCH process with conditional alpha -Stable distribution. Based on the daily returns of hypothetical financial time series, we discuss the results of Bayesian comparison of alternative skewing mechanisms applied in the initial Student-t GARCH framework. Additionally, we present formal Bayesian inference about conditional asymmetry of the distribution of the daily returns in all competing specifications on the basis of the skewness measure defined by Arnold and Groenveld.
The Curious Anomaly of Skewed Judgment Distributions and Systematic Error in the Wisdom of Crowds
Nash, Ulrik W.
2014-01-01
Judgment distributions are often skewed and we know little about why. This paper explains the phenomenon of skewed judgment distributions by introducing the augmented quincunx (AQ) model of sequential and probabilistic cue categorization by neurons of judges. In the process of developing inferences about true values, when neurons categorize cues better than chance, and when the particular true value is extreme compared to what is typical and anchored upon, then populations of judges form skewed judgment distributions with high probability. Moreover, the collective error made by these people can be inferred from how skewed their judgment distributions are, and in what direction they tilt. This implies not just that judgment distributions are shaped by cues, but that judgment distributions are cues themselves for the wisdom of crowds. The AQ model also predicts that judgment variance correlates positively with collective error, thereby challenging what is commonly believed about how diversity and collective intelligence relate. Data from 3053 judgment surveys about US macroeconomic variables obtained from the Federal Reserve Bank of Philadelphia and the Wall Street Journal provide strong support, and implications are discussed with reference to three central ideas on collective intelligence, these being Galton's conjecture on the distribution of judgments, Muth's rational expectations hypothesis, and Page's diversity prediction theorem. PMID:25406078
Skew-varicose instability in two-dimensional generalized Swift-Hohenberg equations.
Weliwita, J A; Rucklidge, A M; Tobias, S M
2011-09-01
We apply analytical and numerical methods to study the linear stability of stripe patterns in two generalizations of the two-dimensional Swift-Hohenberg equation that include coupling to a mean flow. A projection operator is included in our models to allow exact stripe solutions. In the generalized models, stripes become unstable to the skew-varicose, oscillatory skew-varicose, and cross-roll instabilities, in addition to the usual Eckhaus and zigzag instabilities. We analytically derive stability boundaries for the skew-varicose instability in various cases, including several asymptotic limits. We also use numerical techniques to determine eigenvalues and hence stability boundaries of other instabilities. We extend our analysis to both stress-free and no-slip boundary conditions and we note a crossover from the behavior characteristic of no-slip to that of stress-free boundaries as the coupling to the mean flow increases or as the Prandtl number decreases. Close to the critical value of the bifurcation parameter, the skew-varicose instability has the same curvature as the Eckhaus instability provided the coupling to the mean flow is greater than a critical value. The region of stable stripes is completely eliminated by the cross-roll instability for large coupling to the mean flow.
Large-scale age-dependent skewed sex ratio in a sexually dimorphic avian scavenger.
Lambertucci, Sergio A; Carrete, Martina; Donázar, José Antonio; Hiraldo, Fernando
2012-01-01
Age-dependent skewed sex ratios have been observed in bird populations, with adult males generally outnumbering females. This trend is mainly driven by higher female mortality, sometimes associated with anthropogenic factors. Despite the large amount of work on bird sex ratios, research examining the spatial stability of adult sex ratios is extremely scarce. The Andean condor (Vultur gryphus) is the only bird of prey with strong sexual dimorphism favouring males (males are 30% heavier than females). By examining data from most of its South-American range, we show that while the juvenile sex ratio is balanced, or even female-skewed, the sex ratio becomes increasing male-skewed with age, with adult males outnumbering females by >20%, and, in some cases by four times more. This result is consistent across regions and independent of the nature of field data. Reasons for this are unknown but it can be hypothesized that the progressive disappearance of females may be associated with mortality caused by anthropogenic factors. This idea is supported by the asymmetric habitat use by the two sexes, with females scavenging in more humanized areas. Whatever the cause, male-skewed adult sex ratios imply that populations of this endangered scavenger face higher risks of extinction than previously believed. PMID:23029488
Skew angle effects in shingled magnetic recording system with double/triple reader head array
NASA Astrophysics Data System (ADS)
Elidrissi, Moulay Rachid; Sann Chan, Kheong; Greaves, Simon; Kanai, Yasushi; Muraoka, Hiroaki
2014-05-01
Shingled Magnetic Recording (SMR) is a scheme used to extend the life of the current perpendicular magnetic recording technology. SMR enables writing narrow tracks with a wide writer. Currently, SMR employs a single reader and will suffer inter-track interference (ITI) as the tracks become comparable in width to the reader. ITI can be mitigated by using narrower readers; however, narrower readers suffer from increased reader noise. Another approach to combat ITI is to process 2D readback and use ITI cancellation schemes to retrieve the data track. Multiple readbacks can be obtained either with a single reader and multiple revolutions or with a reader array. The former suffers from increased readback latency. In this work, we focus on the latter. When using a reader array, the skew angle poses major challenges. During writing, there is increased adjacent track erasure, and during readback the effective reader pitch varies and there is an increase in the 2D intersymbol interference caused by the rotated reader profile. In this work, we run micromagnetic simulations at different skew angles to train the grain flipping probability model, and then evaluate raw bit channel error rate performance at skew. In particular, we investigate the performance degradation caused by skewing of the 2 or 3 read head array for various read-head geometries.
NASA Technical Reports Server (NTRS)
Deissler, Robert G.
1990-01-01
The variation of the velocity-derivative skewness of a Navier-Stokes flow as the Reynolds number goes toward zero is calculated numerically. The value of the skewness, which has been somewhat controversial, is shown to become small at low Reynolds numbers.
5. View of Clark Fork Vehicle Bridge facing east. Bridge ...
5. View of Clark Fork Vehicle Bridge facing east. Bridge from south shore of Clark Fork River-southernmost span. 1900-era Northern Pacific Railway Bridge in background. - Clark Fork Vehicle Bridge, Spanning Clark Fork River, serves Highway 200, Clark Fork, Bonner County, ID
VIEW OF BRIDGE, LOOKING SOUTHWEST, WITH SOUTHERN PACIFIC RAILROAD BRIDGE ...
VIEW OF BRIDGE, LOOKING SOUTHWEST, WITH SOUTHERN PACIFIC RAILROAD BRIDGE IN BACKGROUND. THE PAVEMENT OF THE NORTH APPROACH IS SEEN BURIED ON THE RIGHT. ROADWAY (CENTER) CROSSES THE USUALLY DRY CHANNEL OF THE SALT RIVER. A BALUSTRADE OF THE MILL AVENUE BRIDGE IS SEEN AT THE LOWER LEFT CORNER - Ash Avenue Bridge, Spanning Salt River at Foot of Ash Avenue, Tempe, Maricopa County, AZ
Reproductive skew and relatedness in social groups of European badgers, Meles meles.
Dugdale, Hannah L; Macdonald, David W; Pope, Lisa C; Johnson, Paul J; Burke, Terry
2008-04-01
Reproductive skew is a measure of the proportion of individuals of each sex that breed in a group and is a valuable measure for understanding the evolution and maintenance of sociality. Here, we provide the first quantification of reproductive skew within social groups of European badgers Meles meles, throughout an 18-year study in a high-density population. We used 22 microsatellite loci to analyse within-group relatedness and demonstrated that badger groups contained relatives. The average within-group relatedness was high (R = 0.20) and approximately one-third of within-group dyads were more likely to represent first-order kin than unrelated pairs. Adult females within groups had higher pairwise relatedness than adult males, due to the high frequency of extra-group paternities, rather than permanent physical dispersal. Spatial clustering of relatives occurred among neighbouring groups, which we suggest was due to the majority of extra-group paternities being attributable to neighbouring males. Reproductive skew was found among within-group candidate fathers (B = 0.26) and candidate mothers (B = 0.07), but not among breeding individuals; our power to detect skew in the latter was low. We use these results to evaluate reproductive skew models. Although badger society best fits the assumptions of the incomplete-control models, our results were not consistent with their predictions. We suggest that this may be due to female control of paternity, female-female reproductive suppression occurring only in years with high food availability resulting in competition over access to breeding sites, extra-group paternity masking the benefits of natal philopatry, and/or the inconsistent occurrence of hierarchies that are linear when established. PMID:18371017
Reynolds, Pamela L; Bruno, John F
2012-01-01
Widespread overharvesting of top consumers of the world's ecosystems has "skewed" food webs, in terms of biomass and species richness, towards a generally greater domination at lower trophic levels. This skewing is exacerbated in locations where exotic species are predominantly low-trophic level consumers such as benthic macrophytes, detritivores, and filter feeders. However, in some systems where numerous exotic predators have been added, sometimes purposefully as in many freshwater systems, food webs are skewed in the opposite direction toward consumer dominance. Little is known about how such modifications to food web topology, e.g., changes in the ratio of predator to prey species richness, affect ecosystem functioning. We experimentally measured the effects of trophic skew on production in an estuarine food web by manipulating ratios of species richness across three trophic levels in experimental mesocosms. After 24 days, increasing macroalgal richness promoted both plant biomass and grazer abundance, although the positive effect on plant biomass disappeared in the presence of grazers. The strongest trophic cascade on the experimentally stocked macroalgae emerged in communities with a greater ratio of prey to predator richness (bottom-rich food webs), while stronger cascades on the accumulation of naturally colonizing algae (primarily microalgae with some early successional macroalgae that recruited and grew in the mesocosms) generally emerged in communities with greater predator to prey richness (the more top-rich food webs). These results suggest that trophic skewing of species richness and overall changes in food web topology can influence marine community structure and food web dynamics in complex ways, emphasizing the need for multitrophic approaches to understand the consequences of marine extinctions and invasions.
Risk-sensitive foraging and the evolution of cooperative breeding and reproductive skew
Poethke, Hans J; Liebig, Jürgen
2008-01-01
Background Group formation and food sharing in animals may reduce variance in resource supply to breeding individuals. For some species it has thus been interpreted as a mechanism of risk avoidance. However, in many groups reproduction is extremely skewed. In such groups resources are not shared equally among the members and inter-individual variance in resource supply may be extreme. The potential consequences of this aspect of group living have not attained much attention in the context of risk sensitive foraging. Results We develop a model of individually foraging animals that share resources for reproduction. The model allows analyzing how mean foraging success, inter-individual variance of foraging success, and the cost of reproduction and offspring raising influence the benefit of group formation and resource sharing. Our model shows that the effects are diametrically opposed in egalitarian groups versus groups with high reproductive skew. For individuals in egalitarian groups the relative benefit of group formation increases under conditions of increasing variance in foraging success and decreasing cost of reproduction. On the other hand individuals in groups with high skew will profit from group formation under conditions of decreasing variance in individual foraging success and increasing cost of reproduction. Conclusion The model clearly demonstrates that reproductive skew qualitatively changes the influence of food sharing on the reproductive output of groups. It shows that the individual benefits of variance reduction in egalitarian groups and variance enhancement in groups with reproductive skew depend critically on ecological and life-history parameters. Our model of risk-sensitive foraging thus allows comparing animal societies as different as spiders and birds in a single framework. PMID:18366668
Bridging Humanism and Behaviorism.
ERIC Educational Resources Information Center
Chu, Lily
1980-01-01
Humanistic behaviorism may provide the necessary bridge between behaviorism and humanism. Perhaps the most humanistic approach to teaching is to learn how certain changes will help students and how these changes can be accomplished. (Author/MLF)
Checa, Antonio G; Cartwright, Julyan H E; Willinger, Marc-Georg
2011-12-01
We confirm with high-resolution techniques the existence of mineral bridges between superposed nacre tablets. In the towered nacre of both gastropods and the cephalopod Nautilus there are large bridges aligned along the tower axes, corresponding to gaps (150-200nm) in the interlamellar membranes. Gaps are produced by the interaction of the nascent tablets with a surface membrane that covers the nacre compartment. In the terraced nacre of bivalves bridges associated with elongated gaps in the interlamellar membrane (>100nm) have mainly been found at or close to the edges of superposed parental tablets. To explain this placement, we hypothesize that the interlamellar membrane breaks due to differences in osmotic pressure across it when the interlamellar space below becomes reduced at an advanced stage of calcification. In no cases are the minor connections between superimposed tablets (<60nm), earlier reported to be mineral bridges, found to be such.
Multiscale model updating of a curved highway bridge
NASA Astrophysics Data System (ADS)
Mensah-Bonsu, Priscilla; Jang, Shinae
2012-04-01
Finite element model updating based on a multi-scale data is demonstrated on a skewed in-service highway bridge. The multi-scale data approach provides an evidence-based method to create a bound of model class to ensure that the optimum model retains physical connectivity to the real structure. The need for this hybrid approach to model selection comes from the challenges of applying model updating to online structural health monitoring (SHM) strategy based on output-only measurements of in-service highway bridges, which should consider various uncertainties. In vibration-based FE model updating methods, the optimum model is selected by minimizing the error between modal parameters of the model and the real structure. A major drawback of model selection is the probability that the optimum model has no physical connectivity with the real structure. This is because a large set of updating parameters is required to increase accuracy. In this paper, an evidence-based approach to model selection using temperature-induced tilts is implemented in which the cyclical static behavior of a bridge is used to create a bound of possible models. This approach has a strong potential to be applicable to large civil structures with sparse array of sensors.
NASA Astrophysics Data System (ADS)
Boswell, S. M.; Zheng, L.; Gordon, R. G.; Dyment, J.
2010-12-01
In past work, reliable paleomagnetic poles have been determined from skewness data by solving for a single additional adjustable parameter, anomalous skewness, assumed to be independent of spreading rate [Petronotis et al. 1992, 1994; Petronotis & Gordon 1999]. Nonetheless, analysis of anomalies in several ocean basins indicate that anomalous skewness depends on spreading rate for spreading half rates less than ≈50 mm/yr [Roest et al., 1992; Dyment et al. 1994]. To facilitate investigation of the influence of spreading-rate dependent anomalous skewness on the determination of paleomagnetic poles determined from skewness, we build on the model for marine magnetic anomalies due to seafloor spreading of Dyment and Arkani-Hamed [1995]. We use this model to estimate anomalous skewness as a function of spreading rate for many anomalies. Synthetic magnetic anomaly profiles for oceanic lithosphere with sloping curving reversal boundaries were produced by forward modeling. Anomalous skewness values for chrons 25n to 33r were visually determined at various spreading rates using two approaches: balancing the shoulders of an anomaly corresponding to a single chron and best matching an anomaly corresponding to a single chron to a synthetic anomaly determined assuming vertical reversal boundaries. The new results may facilitate the determination of paleomagnetic poles from less widely distributed crossings of a magnetic anomaly than were used before. Further implications for determination of paleomagnetic poles for the Pacific plate will be discussed.
Commutative n-ary superalgebras with an invariant skew-symmetric form
NASA Astrophysics Data System (ADS)
Vishnyakova, E. G.
2015-12-01
We study n-ary commutative superalgebras and L∞-algebras that possess a skew-symmetric invariant form, using the derived bracket formalism. This class of superalgebras includes for instance Lie algebras and their n-ary generalizations, commutative associative and Jordan algebras with an invariant form. We give a classification of anti-commutative m-dimensional (m - 3) -ary algebras with an invariant form, and a classification of real simple m-dimensional Lie (m - 3) -algebras with a positive definite invariant form up to isometry. Furthermore, we develop the Hodge Theory for L∞-algebras with a symmetric invariant form, and we describe quasi-Frobenius structures on skew-symmetric n-ary algebras.
Tang, An-Min; Tang, Nian-Sheng
2015-02-28
We propose a semiparametric multivariate skew-normal joint model for multivariate longitudinal and multivariate survival data. One main feature of the posited model is that we relax the commonly used normality assumption for random effects and within-subject error by using a centered Dirichlet process prior to specify the random effects distribution and using a multivariate skew-normal distribution to specify the within-subject error distribution and model trajectory functions of longitudinal responses semiparametrically. A Bayesian approach is proposed to simultaneously obtain Bayesian estimates of unknown parameters, random effects and nonparametric functions by combining the Gibbs sampler and the Metropolis-Hastings algorithm. Particularly, a Bayesian local influence approach is developed to assess the effect of minor perturbations to within-subject measurement error and random effects. Several simulation studies and an example are presented to illustrate the proposed methodologies. PMID:25404574
Optimization Of Mean-Semivariance-Skewness Portfolio Selection Model In Fuzzy Random Environment
NASA Astrophysics Data System (ADS)
Chatterjee, Amitava; Bhattacharyya, Rupak; Mukherjee, Supratim; Kar, Samarjit
2010-10-01
The purpose of the paper is to construct a mean-semivariance-skewness portfolio selection model in fuzzy random environment. The objective is to maximize the skewness with predefined maximum risk tolerance and minimum expected return. Here the security returns in the objectives and constraints are assumed to be fuzzy random variables in nature and then the vagueness of the fuzzy random variables in the objectives and constraints are transformed into fuzzy variables which are similar to trapezoidal numbers. The newly formed fuzzy model is then converted into a deterministic optimization model. The feasibility and effectiveness of the proposed method is verified by numerical example extracted from Bombay Stock Exchange (BSE). The exact parameters of fuzzy membership function and probability density function are obtained through fuzzy random simulating the past dates.
Skew Projection of Echo-Detected EPR Spectra for Increased Sensitivity and Resolution
Bowman, Michael K.; Krzyaniak, Matthew D.; Cruce, Alex A.; Weber, Ralph T.
2013-01-01
The measurement of EPR spectra during pulsed EPR experiments is commonly accomplished by recording the integral of the electron spin echo as the applied magnetic field is stepped through the spectrum. This approach to echo-detected EPR spectral measurement (ED-EPR) limits sensitivity and spectral resolution and can cause gross distortions in the resulting spectra because some of the information present in the electron spin echo is discarded in such measurements. However, Fourier Transformation of echo shapes measured at a series of magnetic field values followed by skew projection onto either a magnetic field or resonance frequency axis can increase both spectral resolution and sensitivity without the need to trade one against the other. Examples of skew-projected spectra with single crystals, glasses and powders show resolution improvements as large as a factor of seven with sensitivity increases of as much as a factor of five. PMID:23644351
Skewed X-chromosome inactivation in women affected by Alzheimer's disease.
Bajic, Vladan; Mandusic, Vesna; Stefanova, Elka; Bozovic, Ana; Davidovic, Radoslav; Zivkovic, Lada; Cabarkapa, Andrea; Spremo-Potparevic, Biljana
2015-01-01
X-chromosome instability has been a long established feature in Alzheimer's disease (AD). Premature centromere division and aneuploidy of the X-chromosome has been found in peripheral blood lymphocytes and neuronal tissue in female AD patients. Interestingly, only one chromosome of the X pair has been affected. These results raised a question, "Is the X-chromosome inactivation pattern altered in peripheral blood lymphocytes of women affected by AD?" To address this question, we analyzed the methylation status of androgen receptor promoter which may show us any deviation from the 50 : 50% X inactivation status in peripheral blood lymphocytes of women with AD. Our results showed skewed inactivation patterns (>90%). These findings suggest that an epigenetic alteration on the inactivation centers of the X-chromosome (or skewing) relates not only to aging, by might be a novel property that could account for the higher incidence of AD in women. PMID:25159673
Muon Tracking Studies in a Skew Parametric Resonance Ionization Cooling Channel
Sy, Amy; Afanaciev, Andre; Derbenev, Yaroslav S.; Johnson, Rolland; Morozov, Vasiliy
2015-09-01
Skew Parametric-resonance Ionization Cooling (SPIC) is an extension of the Parametric-resonance Ionization Cooling (PIC) framework that has previously been explored as the final 6D cooling stage of a high-luminosity muon collider. The addition of skew quadrupoles to the PIC magnetic focusing channel induces coupled dynamic behavior of the beam that is radially periodic. The periodicity of the radial motion allows for the avoidance of unwanted resonances in the horizontal and vertical transverse planes, while still providing periodic locations at which ionization cooling components can be implemented. A first practical implementation of the magnetic field components required in the SPIC channel is modeled in MADX. Dynamic features of the coupled correlated optics with and without induced parametric resonance are presented and discussed.
Skew-Quad Parametric-Resonance Ionization Cooling: Theory and Modeling
Afanaciev, Andre; Derbenev, Yaroslav S.; Morozov, Vasiliy; Sy, Amy; Johnson, Rolland P.
2015-09-01
Muon beam ionization cooling is a key component for the next generation of high-luminosity muon colliders. To reach adequately high luminosity without excessively large muon intensities, it was proposed previously to combine ionization cooling with techniques using a parametric resonance (PIC). Practical implementation of PIC proposal is a subject of this report. We show that an addition of skew quadrupoles to a planar PIC channel gives enough flexibility in the design to avoid unwanted resonances, while meeting the requirements of radially-periodic beam focusing at ionization-cooling plates, large dynamic aperture and an oscillating dispersion needed for aberration corrections. Theoretical arguments are corroborated with models and a detailed numerical analysis, providing step-by-step guidance for the design of Skew-quad PIC (SPIC) beamline.
Bauke, W.; Clark, D.A.; Trujillo, P.B.
1985-01-01
Optical Tooling evolved from traditional surveying, and both technologies are sometimes used interchangeably in large industrial installations, since the instruments and their specialized adapters and supports complement each other well. A unique marriage of both technologies was accomplished in a novel application at LAMPF, the Los Alamos Meson Physics Facility. LAMPF consists of a linear accelerator with multiple target systems, one of which had to be altered to accommodate a new beamline for a neutrino experiment. The new line was to be installed into a crowded beam tunnel and had to be skewed and tilted in compound angles to avoid existing equipment. In this paper we describe how Optical Tooling was used in conjunction with simple alignment and reference fixtures to set fiducials on the magnets and other mechanical components of the beamline, and how theodolites and sight levels were then adapted to align these components along the calculated skew planes. Design tolerances are compared with measured alignment results.
Kinetic investigation of the extrinsic spin Hall effect induced by skew scattering
NASA Astrophysics Data System (ADS)
Cheng, J. L.; Wu, M. W.
2008-02-01
A study of the kinetics of the extrinsic spin Hall conductivity induced by skew scattering is performed using the fully microscopic kinetic spin Bloch equation approach to the (001) GaAs symmetric quantum well. In the steady state, the extrinsic spin Hall current/conductivity vanishes for the linear k dependent spin-orbit coupling and is very small for the cubic k dependent spin-orbit coupling. The spin precession induced by the Dresselhaus/Rashba spin-orbit coupling plays a very important role in the vanishing of the extrinsic spin Hall conductivity in the steady state. An in-plane spin polarization is induced by the skew scattering, with the help of the spin-orbit coupling. This spin polarization is very different from the current-induced spin polarization.
Research on the optimal structure configuration of dither RLG used in skewed redundant INS
NASA Astrophysics Data System (ADS)
Gao, Chunfeng; Wang, Qi; Wei, Guo; Long, Xingwu
2016-05-01
The actual combat effectiveness of weapon equipment is restricted by the performance of Inertial Navigation System (INS), especially in high reliability required situations such as fighter, satellite and submarine. Through the use of skewed sensor geometries, redundant technique has been applied to reduce the cost and improve the reliability of the INS. In this paper, the structure configuration and the inertial sensor characteristics of Skewed Redundant Strapdown Inertial Navigation System (SRSINS) using dithered Ring Laser Gyroscope (RLG) are analyzed. For the dither coupling effects of the dither gyro, the system measurement errors can be amplified either the individual gyro dither frequency is near one another or the structure of the SRSINS is unreasonable. Based on the characteristics of RLG, the research on coupled vibration of dithered RLG in SRSINS is carried out. On the principle of optimal navigation performance, optimal reliability and optimal cost-effectiveness, the comprehensive evaluation scheme of the inertial sensor configuration of SRINS is given.
Olfactory learning skews mushroom body output pathways to steer behavioral choice in Drosophila
Owald, David; Waddell, Scott
2015-01-01
Learning permits animals to attach meaning and context to sensory stimuli. How this information is coded in neural networks in the brain, and appropriately retrieved and utilized to guide behavior, is poorly understood. In the fruit fly olfactory memories of particular value are represented within sparse populations of odor-activated Kenyon cells (KCs) in the mushroom body ensemble. During learning reinforcing dopaminergic neurons skew the mushroom body network by driving zonally restricted plasticity at synaptic junctions between the KCs and subsets of the overall small collection of mushroom body output neurons. Reactivation of this skewed KC-output neuron network retrieves memory of odor valence and guides appropriate approach or avoidance behavior. PMID:26496148
Permanent Magnet Skew Quadrupoles for the Low Emittance LER Lattice of PEP-II
Decker, F.-J.; Anderson, S.; Kharakh, D.; Sullivan, M.; /SLAC
2011-07-05
The vertical emittance of the low energy ring (LER) in the PEP-II B-Factory was reduced by using skew quadrupoles consisting of permanent magnet material. The advantages over electric quadrupoles or rotating existing normal quadrupoles are discussed. To assure a high field quality, a Biot-Savart calculation was used to cancel the natural 12-pole component by using different size poles over a few layers. A magnetic measurement confirmed the high quality of the magnets. After installation and adjusting the original electric 12 skew and 16 normal quadrupoles the emittance contribution from the region close to the interaction point, which was the biggest part in the original design, was considerably reduced. To strengthen the vertical behavior of the LER beam, a low emittance lattice was developed. It lowered the original vertical design emittance from 0.54 nm-rad to 0.034 nm-rad. In order to achieve this, additional skew quadrupoles were required to bring the coupling correction out of the arcs and closer to the detector solenoid in the straight (Fig. 1). It is important, together with low vertical dispersion, that the low vertical emittance is not coupled into the horizontal, which is what we get if the coupling correction continues into the arcs. Further details of the lattice work is described in another paper; here we concentrate on the development of the permanent skew (PSK) quadrupole solution. Besides the permanent magnets there are two other possibilities, using electric magnets or rotating normal quadrupoles. Electric magnets would have required much more additional equipment like magnets stands, power supply, and new vacuum chamber sections. Rotating existing quadrupoles was also not feasible since they are mostly mounted together with a bending magnet on the same support girder.
Skewness-induced asymmetric modulation of small-scale turbulence by large-scale structures
NASA Astrophysics Data System (ADS)
Agostini, Lionel; Leschziner, Michael; Gaitonde, Datta
2016-01-01
Several recent studies discuss of role of skewness of the turbulent velocity fluctuations in near-wall shear layers, in the context of quantifying the correlation between large-scale motions and amplitude variations of small-scale fluctuations—referred to as "modulation." The present study is based on the premise that the skewness of the small-scale fluctuations should be accounted for explicitly in the process of defining their envelope, which characterizes their amplitude variations. This leads to the notion of two envelopes, one for positive and the other for negative small-scale fluctuations, and hence also to two corresponding correlation coefficients. Justification for this concept is provided first by an examination of a high-frequency synthetic signal subjected to realistic skewness-inducing modulation. A new formalism is provided for deriving the two envelopes, and its fidelity is demonstrated for the synthetic test case. The method is then applied to a channel flow at a friction Reynolds number of 4200, for which direct numerical simulation (DNS) data are available. The large-scale and small-scale fields are separated by the empirical mode decomposition method, and the modulation of the small-scale fluctuations by the large scales is examined. Separate maps of the correlation coefficient and of two-point correlations, the latter linking the large-scale motions and the envelopes of the small-scale motions, are derived for the two envelopes pertaining to positive and negative small-scale fluctuations, and these demonstrate a significant sensitivity to the envelope-definition process, especially close to the wall where the skewness of the small-scale fluctuations is the dominant contributor to the total value.
Measuring skewness of red blood cell deformability distribution by laser ektacytometry
Nikitin, S Yu; Priezzhev, A V; Lugovtsov, A E; Ustinov, V D
2014-08-31
An algorithm is proposed for measuring the parameters of red blood cell deformability distribution based on laser diffractometry of red blood cells in shear flow (ektacytometry). The algorithm is tested on specially prepared samples of rat blood. In these experiments we succeeded in measuring the mean deformability, deformability variance and skewness of red blood cell deformability distribution with errors of 10%, 15% and 35%, respectively. (laser biophotonics)
Reynolds, Pamela L.; Bruno, John F.
2012-01-01
Widespread overharvesting of top consumers of the world’s ecosystems has “skewed” food webs, in terms of biomass and species richness, towards a generally greater domination at lower trophic levels. This skewing is exacerbated in locations where exotic species are predominantly low-trophic level consumers such as benthic macrophytes, detritivores, and filter feeders. However, in some systems where numerous exotic predators have been added, sometimes purposefully as in many freshwater systems, food webs are skewed in the opposite direction toward consumer dominance. Little is known about how such modifications to food web topology, e.g., changes in the ratio of predator to prey species richness, affect ecosystem functioning. We experimentally measured the effects of trophic skew on production in an estuarine food web by manipulating ratios of species richness across three trophic levels in experimental mesocosms. After 24 days, increasing macroalgal richness promoted both plant biomass and grazer abundance, although the positive effect on plant biomass disappeared in the presence of grazers. The strongest trophic cascade on the experimentally stocked macroalgae emerged in communities with a greater ratio of prey to predator richness (bottom-rich food webs), while stronger cascades on the accumulation of naturally colonizing algae (primarily microalgae with some early successional macroalgae that recruited and grew in the mesocosms) generally emerged in communities with greater predator to prey richness (the more top-rich food webs). These results suggest that trophic skewing of species richness and overall changes in food web topology can influence marine community structure and food web dynamics in complex ways, emphasizing the need for multitrophic approaches to understand the consequences of marine extinctions and invasions. PMID:22693549
Detection of microscopic defects in optical fiber coatings using angle-resolved skew rays.
Chen, George Y; Monro, Tanya M; Lancaster, David G
2016-09-01
Microscopic defects in optical fiber coatings can be an impending catastrophe for high-power fiber laser and telecommunications systems and are difficult to detect with conventional methods. We demonstrate a highly sensitive interrogation technique that can readily identify faults such as microscopic nicks, scrapes, low-quality recoatings, and internal defects in fibers and their coatings, based on skew ray excitation and angle-resolved analysis.
Detection of microscopic defects in optical fiber coatings using angle-resolved skew rays.
Chen, George Y; Monro, Tanya M; Lancaster, David G
2016-09-01
Microscopic defects in optical fiber coatings can be an impending catastrophe for high-power fiber laser and telecommunications systems and are difficult to detect with conventional methods. We demonstrate a highly sensitive interrogation technique that can readily identify faults such as microscopic nicks, scrapes, low-quality recoatings, and internal defects in fibers and their coatings, based on skew ray excitation and angle-resolved analysis. PMID:27607966
Reproductive skew drives patterns of sexual dimorphism in sponge-dwelling snapping shrimps.
Chak, Solomon Tin Chi; Duffy, J Emmett; Rubenstein, Dustin R
2015-06-22
Sexual dimorphism is typically a result of strong sexual selection on male traits used in male-male competition and subsequent female choice. However, in social species where reproduction is monopolized by one or a few individuals in a group, selection on secondary sexual characteristics may be strong in both sexes. Indeed, sexual dimorphism is reduced in many cooperatively breeding vertebrates and eusocial insects with totipotent workers, presumably because of increased selection on female traits. Here, we examined the relationship between sexual dimorphism and sociality in eight species of Synalpheus snapping shrimps that vary in social structure and degree of reproductive skew. In species where reproduction was shared more equitably, most members of both sexes were physiologically capable of breeding. However, in species where reproduction was monopolized by a single individual, a large proportion of females--but not males--were reproductively inactive, suggesting stronger reproductive suppression and conflict among females. Moreover, as skew increased across species, proportional size of the major chela--the primary antagonistic weapon in snapping shrimps--increased among females and sexual dimorphism in major chela size declined. Thus, as reproductive skew increases among Synalpheus, female-female competition over reproduction appears to increase, resulting in decreased sexual dimorphism in weapon size.
Reproductive skew drives patterns of sexual dimorphism in sponge-dwelling snapping shrimps
Chak, Solomon Tin Chi; Duffy, J. Emmett; Rubenstein, Dustin R.
2015-01-01
Sexual dimorphism is typically a result of strong sexual selection on male traits used in male–male competition and subsequent female choice. However, in social species where reproduction is monopolized by one or a few individuals in a group, selection on secondary sexual characteristics may be strong in both sexes. Indeed, sexual dimorphism is reduced in many cooperatively breeding vertebrates and eusocial insects with totipotent workers, presumably because of increased selection on female traits. Here, we examined the relationship between sexual dimorphism and sociality in eight species of Synalpheus snapping shrimps that vary in social structure and degree of reproductive skew. In species where reproduction was shared more equitably, most members of both sexes were physiologically capable of breeding. However, in species where reproduction was monopolized by a single individual, a large proportion of females—but not males—were reproductively inactive, suggesting stronger reproductive suppression and conflict among females. Moreover, as skew increased across species, proportional size of the major chela—the primary antagonistic weapon in snapping shrimps—increased among females and sexual dimorphism in major chela size declined. Thus, as reproductive skew increases among Synalpheus, female–female competition over reproduction appears to increase, resulting in decreased sexual dimorphism in weapon size. PMID:26041357
A QTL Study for Regions Contributing to Arabidopsis thaliana Root Skewing on Tilted Surfaces.
Vaughn, Laura M; Masson, Patrick H
2011-07-01
Plant root systems must grow in a manner that is dictated by endogenous genetic pathways, yet sensitive to environmental input. This allows them to provide the plant with water and nutrients while navigating a heterogeneous soil environment filled with obstacles, toxins, and pests. Gravity and touch, which constitute important cues for roots growing in soil, have been shown to modulate root architecture by altering growth patterns. This is illustrated by Arabidopsis thaliana roots growing on tilted hard agar surfaces. Under these conditions, the roots are exposed to both gravity and touch stimulation. Consequently, they tend to skew their growth away from the vertical and wave along the surface. This complex growth behavior is believed to help roots avoid obstacles in nature. Interestingly, A. thaliana accessions display distinct growth patterns under these conditions, suggesting the possibility of using this variation as a tool to identify the molecular mechanisms that modulate root behavior in response to their mechanical environment. We have used the Cvi/Ler recombinant inbred line population to identify quantitative trait loci that contribute to root skewing on tilted hard agar surfaces. A combination of fine mapping for one of these QTL and microarray analysis of expression differences between Cvi and Ler root tips identifies a region on chromosome 2 as contributing to root skewing on tilted surfaces, potentially by modulating cell wall composition.
Stress Analysis of a New Disk-Type Variable Torque Slipping Clutch with Skewed Rollers
NASA Astrophysics Data System (ADS)
Feng, Ming; Ono, Kyosuke; Mimura, Kenji
In this paper a new disk type of the variable torque slipping clutch with skewed rollers (VTSCSR) is presented and investigated both theoretically and experimentally. It is comprised of two flat disks, a number of skewed cylindrical rollers, and a cage. The slipping torque is produced by the skewed rollers rolling and slipping between the two disks. Based on the integral equation of the Boussinesq solution, the contact pressures are numerically calculated under the condition that the nonlinear equilibrium equations of the clutch elements are satisfied. By considering both pressure and friction, the components of subsurface stress are calculated from the integration of the Mindlin's subsurface stress equations of concentrated force. A numerical solver is then successfully developed by which the characteristics of the disk-type VTSCSR, including the torque capacity, angular velocities of the roller and cage, contact pressure and von Mises stress, etc, are calculated and illustrated for the typical designs. The influences on the distribution of the von Mises stress by applying various types of profiled rollers to the disk-type VTSCSR are also discussed. It has been found that the full crown with two arcs profiled roller can approximately give rise to the axially uniform distribution of the von Mises stress and therefore satisfies the design principle of the average damage of materials. In addition, the preliminary experiment was done in order to show the feasibility of this design idea and to verify the theoretical torque capacity.
An inconvenient sea truth: spread, steepness, and skewness of surface slopes.
Munk, Walter
2009-01-01
Bréon and Henriot (BH) have collected eight million globally distributed satellite images of sunglitter, which yield a few simple, robust rules about the statistics of surface slopes: 1) constant angular spread, 2) linear steepness, and 3) sigmoid (near stepwise) skewness (all with respect to wind speed). Yet the information is sparse because it says nothing about time and space scales. The BH rules are an inconvenient sea truth, too fundamental to be ignored, too incomplete to be understood. With regard to BH rule 1 (BH:1), I suggest that the constant spread is associated with a wake-like geometry of the short gravities. Steepness linearity (BH:2) remains an enigma. Skewness (BH:3) appears to be correlated with a rather sudden onset of breaking for winds above 4 m s(-1). I do not think that skewness comes from parasitic capillaries. These are tentative conclusions; I look forward to intensive sea-going experiments over the next few years demolishing the proposed interpretations.
A Bayesian estimate of the concordance correlation coefficient with skewed data.
Feng, Dai; Baumgartner, Richard; Svetnik, Vladimir
2015-01-01
Concordance correlation coefficient (CCC) is one of the most popular scaled indices used to evaluate agreement. Most commonly, it is used under the assumption that data is normally distributed. This assumption, however, does not apply to skewed data sets. While methods for the estimation of the CCC of skewed data sets have been introduced and studied, the Bayesian approach and its comparison with the previous methods has been lacking. In this study, we propose a Bayesian method for the estimation of the CCC of skewed data sets and compare it with the best method previously investigated. The proposed method has certain advantages. It tends to outperform the best method studied before when the variation of the data is mainly from the random subject effect instead of error. Furthermore, it allows for greater flexibility in application by enabling incorporation of missing data, confounding covariates, and replications, which was not considered previously. The superiority of this new approach is demonstrated using simulation as well as real-life biomarker data sets used in an electroencephalography clinical study. The implementation of the Bayesian method is accessible through the Comprehensive R Archive Network. PMID:26033433
NASA Astrophysics Data System (ADS)
Denner, Fabian; van Wachem, Berend G. M.
2015-10-01
Total variation diminishing (TVD) schemes are a widely applied group of monotonicity-preserving advection differencing schemes for partial differential equations in numerical heat transfer and computational fluid dynamics. These schemes are typically designed for one-dimensional problems or multidimensional problems on structured equidistant quadrilateral meshes. Practical applications, however, often involve complex geometries that cannot be represented by Cartesian meshes and, therefore, necessitate the application of unstructured meshes, which require a more sophisticated discretisation to account for their additional topological complexity. In principle, TVD schemes are applicable to unstructured meshes, however, not all the data required for TVD differencing is readily available on unstructured meshes, and the solution suffers from considerable numerical diffusion as a result of mesh skewness. In this article we analyse TVD differencing on unstructured three-dimensional meshes, focusing on the non-linearity of TVD differencing and the extrapolation of the virtual upwind node. Furthermore, we propose a novel monotonicity-preserving correction method for TVD schemes that significantly reduces numerical diffusion caused by mesh skewness. The presented numerical experiments demonstrate the importance of accounting for the non-linearity introduced by TVD differencing and of imposing carefully chosen limits on the extrapolated virtual upwind node, as well as the efficacy of the proposed method to correct mesh skewness.
Aminian, Manuchehr; Bernardi, Francesca; Camassa, Roberto; McLaughlin, Richard M
2015-10-01
We study the role geometry plays in the emergence of asymmetries in diffusing passive scalars advected by pressure-driven flows in ducts and pipes of different aspect ratios. We uncover nonintuitive, multi-time-scale behavior gauged by a new statistic, which we term "geometric skewness" S^{G}, which measures instantaneously forming asymmetries at short times due to flow geometry. This signature distinguishes elliptical pipes of any aspect ratio, for which S^{G}=0, from rectangular ducts whose S^{G} is generically nonzero, and, interestingly, shows that a special duct of aspect ratio ≈0.53335 behaves like a circular pipe as its geometric skewness vanishes. Using a combination of exact solutions, novel short-time asymptotics, and Monte Carlo simulations, we establish the relevant time scales for plateaus and extrema in the evolution of the skewness and kurtosis for our class of geometries. For ducts limiting to channel geometries, we present new exact, single-series formulas for the first four moments on slices used to benchmark Monte Carlo simulations. PMID:26550727
Free vibration of composite skewed cylindrical shell panel by finite element method
NASA Astrophysics Data System (ADS)
Haldar, Salil
2008-03-01
In this paper a composite triangular shallow shell element has been used for free vibration analysis of laminated composite skewed cylindrical shell panels. In the present element first-order shear deformation theory has been incorporated by taking transverse displacement and bending rotations as independent field variables. The interpolation function used to approximate transverse displacement is one order higher than for bending rotations. This has made the element free from locking in shear. Two types of mass lumping schemes have been recommended. In one of the mass lumping scheme the effect of rotary inertia has been incorporated in the element formulations. Free vibration of skewed composite cylindrical shell panels having different thickness to radius ratios ( h/R=0.01-0.2), length to radius ratios ( L/R), number of layers and fiber orientation angles have been analyzed following the shallow shell method. The results for few examples obtained in the present analysis have compared with the published results. Some new results of composite skewed cylindrical shell panels have been presented which are expected to be useful to future research in this direction.
4. VIEW OF SILVER BRIDGE (ST. MARY'S BRIDGE), CARRYING COUNTY ...
4. VIEW OF SILVER BRIDGE (ST. MARY'S BRIDGE), CARRYING COUNTY ROAD OVER SOURIS RIVER NEAR SOUTH END OF REFUGE, LOOKING NORTHEAST - Upper Souris National Wildlife Refuge Dams, Souris River Basin, Foxholm, Surrey (England), ND
Axionometric Cutaway of Bridge Structure Shoreham Railroad Bridge, Former ...
Axionometric Cutaway of Bridge Structure - Shoreham Railroad Bridge, Former Addison County Railroad (later, Rutland Railroad, Addison Branch), spanning Lemon Fair River above Richville Pond, west of East Shoreham Road, Shoreham, Addison County, VT
Shoreham Railroad Bridge, Title Sheet Shoreham Railroad Bridge, Former ...
Shoreham Railroad Bridge, Title Sheet - Shoreham Railroad Bridge, Former Addison County Railroad (later, Rutland Railroad, Addison Branch), spanning Lemon Fair River above Richville Pond, west of East Shoreham Road, Shoreham, Addison County, VT
Dog Bridge, view of the deck of the bridge and ...
Dog Bridge, view of the deck of the bridge and rails looking from Linden Lane - National Park Seminary, Bounded by Capitol Beltway (I-495), Linden Lane, Woodstove Avenue, & Smith Drive, Silver Spring, Montgomery County, MD
Coil Creep and Skew-Quadrupole Field Components in the Tevatron
Annala, G.; Harding, D.J.; Syphers, M.J.; /Fermilab
2011-07-11
During the start-up of Run II of the Tevatron Collider program, several issues surfaced which were not present, or not seen as detrimental, during Run I. These included the repeated deterioration of the closed orbit requiring orbit smoothing every two weeks or so, the inability to correct the closed orbit to desired positions due to various correctors running at maximum limits, regions of systematically strong vertical dipole corrections, and the identification of very strong coupling between the two transverse degrees-of-freedom. It became apparent that many of the problems being experienced operationally were connected to a deterioration of the main dipole magnet alignment, and remedial actions were undertaken. However, the alignment alone was not enough to explain the corrector strengths required to handle transverse coupling. With one exception, strong coupling had generally not been an issue in the Tevatron during Run I. Based on experience with the Main Ring, the Tevatron was designed with a very strong skew quadrupole circuit to compensate any quadrupole alignment and skew quadrupole field errors that might present themselves. The circuit was composed of 48 correctors placed evenly throughout the arcs, 8 per sector, evenly placed in every other cell. Other smaller circuits were installed but not initially needed or commissioned. These smaller circuits were composed of individual skew quadrupole correctors on either side of the long straight sections. These circuits were tuned by first bringing the horizontal and vertical tunes near each other. The skew quadrupoles were then adjusted to minimize tune split, usually to less than 0.003. Initially, the main skew quad circuit (designated T:SQ) could accomplish this global decoupling with only 4% of its possible current, and the smaller circuits were not required at all. The start-up of Run Ib was complicated by what was later discovered to be a rolled triplet quadrupole magnet in one of the Interaction Regions
1. WESTERN VIEW OF BRIDGE PLAZA, SHOWING MEMORIAL BRIDGE AT ...
1. WESTERN VIEW OF BRIDGE PLAZA, SHOWING MEMORIAL BRIDGE AT LEFT AND THE ROCK CREEK AND POTOMAC PARKWAY RAMP AT RIGHT. VIEW TAKEN FROM THE REAR OF THE LINCOLN MEMORIAL. - Arlington Memorial Bridge, Boundary Channel Extension, Spanning Mount Vernon Memorial Highway & Boundary Channel, Washington, District of Columbia, DC
Bridge Types: Suspension Bridge Spans, Section AA; Cantilever Truss Spans, ...
Bridge Types: Suspension Bridge Spans, Section A-A; Cantilever Truss Spans, Section B-B; Through Truss Spans, Section C-C; Deck Truss Spans, Section D-D - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA
Ng, Benjamin; Cai, Wenju; Walsh, Kevin
2014-08-12
A positive Indian Ocean Dipole (IOD) tends to have stronger cold sea surface temperature anomalies (SSTAs) over the eastern Indian Ocean with greater impacts than warm SSTAs that occur during its negative phase. Two feedbacks have been suggested as the cause of positive IOD skewness, a positive Bjerknes feedback and a negative SST-cloud-radiation (SCR) feedback, but their relative importance is debated. Using inter-model statistics, we show that the most important process for IOD skewness is an asymmetry in the thermocline feedback, whereby SSTAs respond to thermocline depth anomalies more strongly during the positive phase than negative phase. This asymmetric thermocline feedback drives IOD skewness despite positive IODs receiving greater damping from the SCR feedback. In response to global warming, although the thermocline feedback strengthens, its asymmetry between positive and negative IODs weakens. This behaviour change explains the reduction in IOD skewness that many models display under global warming.
Using skew-logistic probability density function as a model for age-specific fertility rate pattern.
Asili, Sahar; Rezaei, Sadegh; Najjar, Lotfollah
2014-01-01
Fertility rate is one of the most important global indexes. Past researchers found models which fit to age-specific fertility rates. For example, mixture probability density functions have been proposed for situations with bi-modal fertility patterns. This model is less useful for unimodal age-specific fertility rate patterns, so a model based on skew-symmetric (skew-normal) pdf was proposed by Mazzuco and Scarpa (2011) which was flexible for unimodal and bimodal fertility patterns. In this paper, we introduce skew-logistic probability density function as a better model: its residuals are less than those of the skew-normal model and it can more precisely estimate the parameters of the model. PMID:24967404
BUILDING "BRIDGES" WITH QUALITY ASSURANCE
The papr describes how, rather than building "bridges" across centuries, quality assurance (QA) personnel have the opportunity to build bridges across technical disciplines, between public and private organizations, and between different QA groups. As reviewers and auditors of a...
ERIC Educational Resources Information Center
Bohnen, Elizabeth; Klie, Judy
This report describes BRIDGES, an employment equity special measures training program developed by the City of Toronto (Ontario, Canada). It was designed to help women employees move from their traditional jobs into trades, technical or operation (TTO) jobs within their own organization. The program is a combination of classroom sessions, shop…
ERIC Educational Resources Information Center
Wasta, Stephanie; Scott, Margaret
1998-01-01
Describes a theme cycle called "Building Bridges to China" developed for third grade students that focuses on the similarities between the lives of children and families in China and the United States. Explains that the theme cycle addresses the National Geography Standards and three of the National Council for the Social Studies standards. (CMK)
ERIC Educational Resources Information Center
Teaching Science, 2015
2015-01-01
This project is for a team of students (groups of two or three are ideal) to design and construct a model of a single-span bridge, using plastic drinking straws as the building material. All steps of the design, construction, testing and critiquing stages should be recorded by students in a journal. Students may like to include labelled diagrams,…
ERIC Educational Resources Information Center
Gohdes, William
1995-01-01
Although tech prep is still in its infancy in Georgia, increasing numbers of students are entering technical institutes after having completed the secondary-level component of tech prep programs. Georgia's technical institutes must begin the process of developing bridge programs to help adult students with no tech prep experience develop academic…
ERIC Educational Resources Information Center
Salter, Colin
2009-01-01
The political context of the conversion of the Historic Tramway Bridge, adjacent to Sandon Point in Bulli (NSW, Australia), and how this was exploited to serve predetermined ends, illustrates that technologies can be designed to have particular social (and political) effects. Through reflection on this relatively small engineering project, this…
ERIC Educational Resources Information Center
Olcott, Marianina
2007-01-01
This paper seeks to explain the epistemological bases for the two cultures and to show why this disciplinary divide continues to plague American academic culture. Next, we discuss strategies for bridging the two cultures through general education curricula which promote mutual understanding of the two cultures while educating students in basic…
Bridging Disciplinary Boundaries
ERIC Educational Resources Information Center
Mei, Linda
2009-01-01
Interdisciplinary education promotes the unity of knowledge by bridging the cultural divide between the social constructs of disciplines and encourages the development of knowledge to enhance society. As an inquiry-based and relevant approach that expands and advances knowledge, interdisciplinary education facilitates creativity and flexibility,…
ERIC Educational Resources Information Center
Kroto, Joseph J.
1988-01-01
Describes interdisciplinary activities with real-world applications ranging from science to mathematics to technology. Cites the study and construction of model bridges as a way for students to learn about engineering concepts and some of their relationships. States that the exercise enhanced teacher cooperation between the different fields. (RT)
ERIC Educational Resources Information Center
Roy, Michael; Doss, Laurie K.
2007-01-01
The Building Migratory Bridges (BOMB) program--a collaboration between the Marvel wood School and Audubon Sharon in Connecticut and Conservation Research Education Action (CR EA), a U.S. not-for-profit in Panama--uses nontropical migratory bird research in the United States and Panama to demonstrate how negative environmental impacts in one…
ERIC Educational Resources Information Center
Netzer, Greg
1995-01-01
Discusses a model water quality monitoring project, Project Bridge, established to train minority girls about to enter eighth grade in scientific procedures followed by hands-on experimentation. Students spent a week monitoring water in an urban stream and analyzing results. (LZ)
ERIC Educational Resources Information Center
Bisogno, Janet; JeanPierre, Bobby
2008-01-01
The West Point Bridge Design (WPBD) building project engages students in project-based learning by giving them a real-life problem to solve. By using technology, students are able to become involved in solving problems that they normally would not encounter. Involvement with interactive websites, such as WPBD, assists students in using…
ERIC Educational Resources Information Center
Lum, Lydia
2009-01-01
Since its inception in 2000, Pan-Asian American Community House's (PAACH's) education mission has bridged Asian-American studies to student life. PAACH initiatives have helped spread Asian-American diaspora to thousands of students at the University of Pennsylvania. They have also helped students determine for themselves what it means to be a…
Godler, David E; Inaba, Yoshimi; Schwartz, Charles E; Bui, Quang M; Shi, Elva Z; Li, Xin; Herlihy, Amy S; Skinner, Cindy; Hagerman, Randi J; Francis, David; Amor, David J; Metcalfe, Sylvia A; Hopper, John L; Slater, Howard R
2015-01-01
Methylation of the fragile X mental retardation 1 (FMR1) exon 1/intron 1 boundary positioned fragile X related epigenetic element 2 (FREE2), reveals skewed X-chromosome inactivation (XCI) in fragile X syndrome full mutation (FM: CGG > 200) females. XCI skewing has been also linked to abnormal X-linked gene expression with the broader clinical impact for sex chromosome aneuploidies (SCAs). In this study, 10 FREE2 CpG sites were targeted using methylation specific quantitative melt analysis (MS-QMA), including 3 sites that could not be analysed with previously used EpiTYPER system. The method was applied for detection of skewed XCI in FM females and in different types of SCA. We tested venous blood and saliva DNA collected from 107 controls (CGG < 40), and 148 FM and 90 SCA individuals. MS-QMA identified: (i) most SCAs if combined with a Y chromosome test; (ii) locus-specific XCI skewing towards the hypomethylated state in FM females; and (iii) skewed XCI towards the hypermethylated state in SCA with 3 or more X chromosomes, and in 5% of the 47,XXY individuals. MS-QMA output also showed significant correlation with the EpiTYPER reference method in FM males and females (P < 0.0001) and SCAs (P < 0.05). In conclusion, we demonstrate use of MS-QMA to quantify skewed XCI in two applications with diagnostic utility. PMID:26132880
Godler, David E; Inaba, Yoshimi; Schwartz, Charles E; Bui, Quang M; Shi, Elva Z; Li, Xin; Herlihy, Amy S; Skinner, Cindy; Hagerman, Randi J; Francis, David; Amor, David J; Metcalfe, Sylvia A; Hopper, John L; Slater, Howard R
2015-07-01
Methylation of the fragile X mental retardation 1 (FMR1) exon 1/intron 1 boundary positioned fragile X related epigenetic element 2 (FREE2), reveals skewed X-chromosome inactivation (XCI) in fragile X syndrome full mutation (FM: CGG > 200) females. XCI skewing has been also linked to abnormal X-linked gene expression with the broader clinical impact for sex chromosome aneuploidies (SCAs). In this study, 10 FREE2 CpG sites were targeted using methylation specific quantitative melt analysis (MS-QMA), including 3 sites that could not be analysed with previously used EpiTYPER system. The method was applied for detection of skewed XCI in FM females and in different types of SCA. We tested venous blood and saliva DNA collected from 107 controls (CGG < 40), and 148 FM and 90 SCA individuals. MS-QMA identified: (i) most SCAs if combined with a Y chromosome test; (ii) locus-specific XCI skewing towards the hypomethylated state in FM females; and (iii) skewed XCI towards the hypermethylated state in SCA with 3 or more X chromosomes, and in 5% of the 47,XXY individuals. MS-QMA output also showed significant correlation with the EpiTYPER reference method in FM males and females (P < 0.0001) and SCAs (P < 0.05). In conclusion, we demonstrate use of MS-QMA to quantify skewed XCI in two applications with diagnostic utility.
NASA Astrophysics Data System (ADS)
Boswell, S. M.; Zheng, L.; Gordon, R. G.; Dyment, J.
2011-12-01
An improved understanding of the spreading-rate dependence of anomalous skewness from magnetic anomalies due to seafloor spreading will allow for better constraints on apparent polar wander paths, plate reconstructions, and the magnetic and thermal structure of oceanic lithosphere. Anomalous skewness, which is the difference between experimentally determined skewness and skewness expected from simple magnetization models with vertical reversal boundaries, has been observed to vary as a function of spreading rate, decreasing with increasing spreading rate and becoming negligible at spreading half-rates exceeding about 55 mm/a [Roest et al. 1992; Dyment et al. 1994]. In our analysis, we determine model-based estimates of anomalous skewness as a function of spreading rate for each anomaly. We do so by creating many synthetic profiles using the model of Dyment and Arkani-Hamed (1995), which was specifically constructed to produce anomalies with anomalous skewness consistent with observed anomalies. We experimentally determine the phase shift that causes the resulting synthetic magnetic anomaly to best match a profile produced from a "standard" model for anomalies due to seafloor spreading that assumes simple vertical reversal boundaries. We present results for those anomalies between 12r and 33r from which reliable paleomagnetic poles may potentially be determined. Differences in anomalous skewness for different anomalies determined at the same spreading rate can be attributed to the sequence effect, that is, the effect on the shape of a magnetic anomaly above seafloor of a single polarity chron of the magnetization of neighboring blocks of lithosphere magnetized during other chrons. We find that the sequence effect is smaller than we expected with the largest difference being between the results for anomaly 25r and those for anomaly 33r, for which the difference is 14 degrees at a 10 mm/a half-rate. Results for other anomalies lie between these two. We also infer a
Bridged ferrocenes. 10. Structural phenomena
Hillman, M.; Fujita, E.; Dauplaise, H.; Kvick, A.; Kerber, R.C.
1984-01-01
The structures of 1,1',2,2'-bis(tetramethylene)ferrocene, I, 1,1',2,2',4,4'-tris(tetramethylene)ferrocene, II, and 1,1',2,2',4,4'-tris(pentamethylene)ferrocene, III, are given and are compared to the previously determined structure of 1,1',2,2',4,4'-tris(trimethylene)ferrocene, IV. The iron-to-ring distances are consistent with the reported Moessbauer spectra and redox potentials. The cyclopentadienyl rings are eclipsed in the compounds with trimethylene and pentamethylene bridges but are staggered by 12-14 in the compounds with tetramethylene bridges. In compounds with tetra- and pentamethylene bridges the presence of staggering or eclipsing is attributed to the need to avoid eclipsing of the protons in the bridges. In the compound with three trimethylene bridges, the shortness of the bridges is of primary importance. The staggered conformation observed in I and II may be the source of the apparent anomalies observed in the ring-proton region of the NMR spectra of bridged ferrocenes. The bridge-proton region of the NMR spectra at 360 MHz are given for I and other bridged ferrocenes. Disorder of the bridge carbons observed in the crystals are correlated with the flipping of the bridges observed in the NMR spectra. 30 references, 8 tables.
Molecular engineering with bridged polysilsesquioxanes
LOY,DOUGLAS A.; SHEA,KENNETH J.
2000-05-09
Bridged polysilsesquioxanes are a class of hybrid organic-inorganic materials that permit molecular engineering of bulk properties including porosity. Prepared by sol-gel polymerization of monomers with two or more trialkoxysilyl groups, the materials are highly cross-linked amorphous polymers that are readily obtained as gels. The bridging configuration of the hydrocarbon group insures that network polymers are readily formed and that the organic functionality is homogeneously distributed throughout the polymeric scaffolding at the molecular level. This permits the bulk properties, including surface area, pore size, and dielectric constant to be engineered through the selection of the bridging organic group. Numerous bridging groups have been incorporated. This presentation will focus on the effects that the length, flexibility, and substitution geometry of the hydrocarbon bridging groups have on the properties of the resulting bridged polysilsesquioxanes. Details of the preparation, characterization, and some structure property relationships of these bridged polysilsesquioxanes will be given.
Heat transfer in rotating serpentine passages with trips skewed to the flow
NASA Astrophysics Data System (ADS)
Johnson, B. V.; Wagner, J. H.; Steuber, G. D.; Yeh, F. C.
Experiments were conducted to determine the effects of buoyancy and Coriolis forces on heat transfer in turbine blade internal coolant passages. The experiments were conducted with a large scale, multi-pass, heat transfer model with both radially inward and outward flow. Trip strips, skewed at 45 deg to the flow direction, were machined on the leading and trailing surfaces of the radial coolant passages. An analysis of the governing flow equations showed that four parameters influence the heat transfer in rotating passages: coolant-to-wall temperature, rotation number, Reynolds number, and radius-to-passage hydraulic diameter ratio. The first three of these four parameters were varied over ranges which are typical of advanced gas turbine engine operating conditions. Results were correlated and compared to previous results from similar stationary and rotating models with smooth walls and with trip strips normal to the flow direction. The heat transfer coefficients on surfaces, where the heat transfer decreased with rotation and buoyancy, decreased to as low as 40 percent of the value without rotation. However, the maximum values of the heat transfer coefficients with high rotation were only slightly above the highest levels previously obtained with the smooth wall models. It was concluded that (1) both Coriolis and buoyancy effects must be considered in turbine blade cooling designs with trip strips, (2) the effects of rotation are markedly different depending upon the flow direction, and (3) the heat transfer with skewed trip strips is less sensitive to buoyancy than the heat transfer in models with either smooth or normal trips. Therefore, skewed trip strips rather than normal trip strips are recommended and geometry-specific tests are required for accurate design information.
Heat transfer in rotating serpentine passages with trips skewed to the flow
NASA Technical Reports Server (NTRS)
Johnson, B. V.; Wagner, J. H.; Steuber, G. D.; Yeh, F. C.
1992-01-01
Experiments were conducted to determine the effects of buoyancy and Coriolis forces on heat transfer in turbine blade internal coolant passages. The experiments were conducted with a large scale, multi-pass, heat transfer model with both radially inward and outward flow. Trip strips, skewed at 45 deg to the flow direction, were machined on the leading and trailing surfaces of the radial coolant passages. An analysis of the governing flow equations showed that four parameters influence the heat transfer in rotating passages: coolant-to-wall temperature, rotation number, Reynolds number, and radius-to-passage hydraulic diameter ratio. The first three of these four parameters were varied over ranges which are typical of advanced gas turbine engine operating conditions. Results were correlated and compared to previous results from similar stationary and rotating models with smooth walls and with trip strips normal to the flow direction. The heat transfer coefficients on surfaces, where the heat transfer decreased with rotation and buoyancy, decreased to as low as 40 percent of the value without rotation. However, the maximum values of the heat transfer coefficients with high rotation were only slightly above the highest levels previously obtained with the smooth wall models. It was concluded that (1) both Coriolis and buoyancy effects must be considered in turbine blade cooling designs with trip strips, (2) the effects of rotation are markedly different depending upon the flow direction, and (3) the heat transfer with skewed trip strips is less sensitive to buoyancy than the heat transfer in models with either smooth or normal trips. Therefore, skewed trip strips rather than normal trip strips are recommended and geometry-specific tests are required for accurate design information.
Electrical Actuation Technology Bridging
NASA Technical Reports Server (NTRS)
Hammond, Monica (Compiler); Sharkey, John (Compiler)
1993-01-01
This document contains the proceedings of the NASA Electrical Actuation Technology Bridging (ELA-TB) Workshop held in Huntsville, Alabama, September 29-October 1, 1992. The workshop was sponsored by the NASA Office of Space Systems Development and Marshall Space Flight Center (MSFC). The workshop addressed key technologies bridging the entire field of electrical actuation including systems methodology, control electronics, power source systems, reliability, maintainability, and vehicle health management with special emphasis on thrust vector control (TVC) applications on NASA launch vehicles. Speakers were drawn primarily from industry with participation from universities and government. In addition, prototype hardware demonstrations were held at the MSFC Propulsion Laboratory each afternoon. Splinter sessions held on the final day afforded the opportunity to discuss key issues and to provide overall recommendations. Presentations are included in this document.
Steel bridge retrofit evaluation
NASA Astrophysics Data System (ADS)
Prine, David W.
1998-03-01
The development of a retrofit design aimed at retarding or eliminating fatigue crack growth in a large bridge can be a very difficult and expensive procedure. Analytical techniques frequently do not provide sufficient accuracy when applied to complex structural details. The Infrastructure Technology Institute (ITI) of Northwestern University, under contract to the California Department of Transportation (Caltrans), recently applied experimental state-of-the-art NDE technology to the Interstate 80 bridge over the Sacramento River near Sacramento, California (Bryte Bend). Acoustic emission monitoring was applied in conjunction with strain gage monitoring to aid in characterizing the retrofits' effect on existing active fatigue cracks. The combined test results clearly showed that one retrofit design was superior to the other.
Measuring skew in average surface roughness as a function of surface preparation
NASA Astrophysics Data System (ADS)
Stahl, Mark T.
2015-08-01
Characterizing surface roughness is important for predicting optical performance. Better measurement of surface roughness reduces polishing time, saves money and allows the science requirements to be better defined. This study characterized statistics of average surface roughness as a function of polishing time. Average surface roughness was measured at 81 locations using a Zygo® white light interferometer at regular intervals during the polishing process. Each data set was fit to a normal and Largest Extreme Value (LEV) distribution; then tested for goodness of fit. We show that the skew in the average data changes as a function of polishing time.
Eigenvalue analysis of an irreversible random walk with skew detailed balance conditions.
Sakai, Yuji; Hukushima, Koji
2016-04-01
An irreversible Markov-chain Monte Carlo (MCMC) algorithm with skew detailed balance conditions originally proposed by Turitsyn et al. is extended to general discrete systems on the basis of the Metropolis-Hastings scheme. To evaluate the efficiency of our proposed method, the relaxation dynamics of the slowest mode and the asymptotic variance are studied analytically in a random walk on one dimension. It is found that the performance in irreversible MCMC methods violating the detailed balance condition is improved by appropriately choosing parameters in the algorithm. PMID:27176439
A method for skew-free distribution of digital signals using matched variable delay lines
NASA Astrophysics Data System (ADS)
Knight, Thomas; Wu, Henry
1992-03-01
The ability to distribute signals to all parts of a circuit with precisely controlled and known delays is essential in large, high-speed digital systems. We present a technique by which a signal driver can adjust the arrival time of the signal at the end of the wire using a pair of matched variable delay lines. We show how this idea can be implemented requiring no extra wiring, and how it can be extended to distribute signals skew-free to receivers along the signal run as well as the receiving end. We demonstrate how this scheme can be implemented as part of the pad and scan logic of a VLSI chip.
Asymptotic of the Solutions of Hyperbolic Equations with a Skew-Symmetric Perturbation
NASA Astrophysics Data System (ADS)
Gallagher, Isabelle
1998-12-01
Using methods introduced by S. Schochet inJ. Differential Equations114(1994), 476-512, we compute the first term of an asymptotic expansion of the solutions of hyperbolic equations perturbated by a skew-symmetric linear operator. That result is first applied to two systems describing the motion of geophysic fluids: the rotating Euler equations and the primitive system of the quasigeostrophic equations. Finally in the last part, we study the slightly compressible Euler equations by application of that same result.
Stability of a cantilevered skew inhomogeneous plate in supersonic gas flow
NASA Astrophysics Data System (ADS)
Isaulova, T. N.; Lavit, I. M.
2011-07-01
This paper considers the vibrations of a skew inhomogeneous plate in gas flow. The plate is clamped in a certain section of one of its sides. Interaction of the flow with the plate is described using piston theory. The problem solution is based on the Hamilton's variational principle and finite element method. The calculation results are compared with known data of theoretical studies and experiments. For the inhomogeneous plate, similarity parameters were established for the problem, which, in practically important cases, appears to be self-similar for one of the similarity parameters. This allows one to reduce the solution of this problem to the solution of an algebraic eigenvalue problem.
Extrinsic spin Hall effect induced by resonant skew scattering in graphene.
Ferreira, Aires; Rappoport, Tatiana G; Cazalilla, Miguel A; Castro Neto, A H
2014-02-14
We show that the extrinsic spin Hall effect can be engineered in monolayer graphene by decoration with small doses of adatoms, molecules, or nanoparticles originating local spin-orbit perturbations. The analysis of the single impurity scattering problem shows that intrinsic and Rashba spin-orbit local couplings enhance the spin Hall effect via skew scattering of charge carriers in the resonant regime. The solution of the transport equations for a random ensemble of spin-orbit impurities reveals that giant spin Hall currents are within the reach of the current state of the art in device fabrication. The spin Hall effect is robust with respect to thermal fluctuations and disorder averaging.
Extrinsic Spin Hall Effect Induced by Resonant Skew Scattering in Graphene
NASA Astrophysics Data System (ADS)
Ferreira, Aires; Rappoport, Tatiana G.; Cazalilla, Miguel A.; Castro Neto, A. H.
2014-02-01
We show that the extrinsic spin Hall effect can be engineered in monolayer graphene by decoration with small doses of adatoms, molecules, or nanoparticles originating local spin-orbit perturbations. The analysis of the single impurity scattering problem shows that intrinsic and Rashba spin-orbit local couplings enhance the spin Hall effect via skew scattering of charge carriers in the resonant regime. The solution of the transport equations for a random ensemble of spin-orbit impurities reveals that giant spin Hall currents are within the reach of the current state of the art in device fabrication. The spin Hall effect is robust with respect to thermal fluctuations and disorder averaging.
Measuring Skew in Average Surface Roughness as a Function of Surface Preparation
NASA Technical Reports Server (NTRS)
Stahl, Mark
2015-01-01
Characterizing surface roughness is important for predicting optical performance. Better measurement of surface roughness reduces polishing time, saves money and allows the science requirements to be better defined. This study characterized statistics of average surface roughness as a function of polishing time. Average surface roughness was measured at 81 locations using a Zygo white light interferometer at regular intervals during the polishing process. Each data set was fit to a normal and Largest Extreme Value (LEV) distribution; then tested for goodness of fit. We show that the skew in the average data changes as a function of polishing time.
Measuring Skew in Average Surface Roughness as a Function of Surface Preparation
NASA Technical Reports Server (NTRS)
Stahl, Mark T.
2015-01-01
Characterizing surface roughness is important for predicting optical performance. Better measurement of surface roughness reduces grinding saving both time and money and allows the science requirements to be better defined. In this study various materials are polished from a fine grind to a fine polish. Each sample's RMS surface roughness is measured at 81 locations in a 9x9 square grid using a Zygo white light interferometer at regular intervals during the polishing process. Each data set is fit with various standard distributions and tested for goodness of fit. We show that the skew in the RMS data changes as a function of polishing time.
A variational Bayesian approach for inverse problems with skew-t error distributions
NASA Astrophysics Data System (ADS)
Guha, Nilabja; Wu, Xiaoqing; Efendiev, Yalchin; Jin, Bangti; Mallick, Bani K.
2015-11-01
In this work, we develop a novel robust Bayesian approach to inverse problems with data errors following a skew-t distribution. A hierarchical Bayesian model is developed in the inverse problem setup. The Bayesian approach contains a natural mechanism for regularization in the form of a prior distribution, and a LASSO type prior distribution is used to strongly induce sparseness. We propose a variational type algorithm by minimizing the Kullback-Leibler divergence between the true posterior distribution and a separable approximation. The proposed method is illustrated on several two-dimensional linear and nonlinear inverse problems, e.g. Cauchy problem and permeability estimation problem.
Climbing techniques for bridge inspection
NASA Astrophysics Data System (ADS)
Kaslan, Erol C.
1998-03-01
California has about 24,000 publicly owned bridges that require routine structural evaluations to comply with National Bridge Inspection Standard (NBIS) mandates. Of these, about 800 are identified as possessing fatigue prone or fracture critical details requiring thorough tactile investigations. Gaining access to bridge elements to perform these investigations has become increasingly difficult and costly. The traditional uses of under bridge inspection trucks, lift equipment and rigging are economically and practically limited by bridge size, structure type, traffic demands and support costs. In some cases, bridges that have become damaged by earthquakes cannot safely support the loads of heavy personnel lift equipment. The California Department of Transportation (Caltrans)'s Office of Structural Materials and Office of Structure Maintenance and Investigations evaluated the use of rock climbing and mountaineering techniques as an alternative means of gaining access for bridge inspections. Under a small research grant, a bridge climbing training course was developed through a local University of California outdoor recreation group and 7 engineers and technicians were initially trained. A comprehensive Code of Safe Practices was created and standards of training, procedures and equipment required for bridge inspections were established. A successful climb investigation on a large, previously inaccessible arch bridge was completed at the end of the training that proved the techniques safe, economical and effective. Within one year, 20 bridge maintenance engineers were trained, and a formal program was established to organize, schedule, equip and certify engineers and technicians for bridge climbing. Several other offices within Caltrans as well as the California Department of Water Resources have since adopted these techniques for specialized structural inspection tasks. Climbing techniques are now used routinely in California as an alterative means of gaining access
Streambed stresses and flow around bridge piers
Parola, A.C.; Ruhl, K.J.; Hagerty, D.J.; Brown, B.M.; Ford, D.L.; Korves, A.A.
1996-01-01
Scour of streambed material around bridge foundations by floodwaters is the leading cause of catastrophic bridge failure in the United States. The potential for scour and the stability of riprap used to protect the streambed from scour during extreme flood events must be known to evaluate the likelihood of bridge failure. A parameter used in estimating the potential for scour and removal of riprap protection is the time-averaged shear stress on the streambed often referred to as boundary stress. Bridge components, such as bridge piers and abutments, obstruct flow and induce strong vortex systems that create streambed or boundary stresses significantly higher than those in unobstructed flow. These locally high stresses can erode the streambed around pier and abutment foundations to the extent that the foundation is undermined, resulting in settlement or collapse of bridge spans. The purpose of this study was to estimate streambed stresses at a bridge pier under full-scale flow conditions and to compare these stresses with those obtained previously in small-scale model studies. Two-dimensional velocity data were collected for three flow conditions around a bridge pier at the Kentucky State Highway 417 bridge over the Green River at Greensburg in Green County, Ky. Velocity vector plots and the horizontal component of streambed stress contour plots were developed from the velocity data. The streambed stress contours were developed using both a near-bed velocity and velocity gradient method. Maximum near-bed velocities measured at the pier for the three flow conditions were 1.5, 1.6, and 2.0 times the average near-bed velocities measured in the upstream approach flow. Maximum streambed stresses for the three flow conditions were determined to be 10, 15, and 36 times the streambed stresses of the upstream approach flow. Both the near-bed velocity measurements and approximate maximum streambed stresses at the full-scale pier were consistent with those observed in
Prediction of Scour Depth around Bridge Piers using Adaptive Neuro-Fuzzy Inference Systems (ANFIS)
NASA Astrophysics Data System (ADS)
Valyrakis, Manousos; Zhang, Hanqing
2014-05-01
Earth's surface is continuously shaped due to the action of geophysical flows. Erosion due to the flow of water in river systems has been identified as a key problem in preserving ecological health of river systems but also a threat to our built environment and critical infrastructure, worldwide. As an example, it has been estimated that a major reason for bridge failure is due to scour. Even though the flow past bridge piers has been investigated both experimentally and numerically, and the mechanisms of scouring are relatively understood, there still lacks a tool that can offer fast and reliable predictions. Most of the existing formulas for prediction of bridge pier scour depth are empirical in nature, based on a limited range of data or for piers of specific shape. In this work, the application of a Machine Learning model that has been successfully employed in Water Engineering, namely an Adaptive Neuro-Fuzzy Inference System (ANFIS) is proposed to estimate the scour depth around bridge piers. In particular, various complexity architectures are sequentially built, in order to identify the optimal for scour depth predictions, using appropriate training and validation subsets obtained from the USGS database (and pre-processed to remove incomplete records). The model has five variables, namely the effective pier width (b), the approach velocity (v), the approach depth (y), the mean grain diameter (D50) and the skew to flow. Simulations are conducted with data groups (bed material type, pier type and shape) and different number of input variables, to produce reduced complexity and easily interpretable models. Analysis and comparison of the results indicate that the developed ANFIS model has high accuracy and outstanding generalization ability for prediction of scour parameters. The effective pier width (as opposed to skew to flow) is amongst the most relevant input parameters for the estimation.
Maximum Parsimony and the Skewness Test: A Simulation Study of the Limits of Applicability
Määttä, Jussi; Roos, Teemu
2016-01-01
The maximum parsimony (MP) method for inferring phylogenies is widely used, but little is known about its limitations in non-asymptotic situations. This study employs large-scale computations with simulated phylogenetic data to estimate the probability that MP succeeds in finding the true phylogeny for up to twelve taxa and 256 characters. The set of candidate phylogenies are taken to be unrooted binary trees; for each simulated data set, the tree lengths of all (2n − 5)!! candidates are computed to evaluate quantities related to the performance of MP, such as the probability of finding the true phylogeny, the probability that the tree with the shortest length is unique, the probability that the true phylogeny has the shortest tree length, and the expected inverse of the number of trees sharing the shortest length. The tree length distributions are also used to evaluate and extend the skewness test of Hillis for distinguishing between random and phylogenetic data. The results indicate, for example, that the critical point after which MP achieves a success probability of at least 0.9 is roughly around 128 characters. The skewness test is found to perform well on simulated data and the study extends its scope to up to twelve taxa. PMID:27035667
Using Skewness and the First-Digit Phenomenon to Identify Dynamical Transitions in Cardiac Models
Seenivasan, Pavithraa; Easwaran, Soumya; Sridhar, Seshan; Sinha, Sitabhra
2016-01-01
Disruptions in the normal rhythmic functioning of the heart, termed as arrhythmia, often result from qualitative changes in the excitation dynamics of the organ. The transitions between different types of arrhythmia are accompanied by alterations in the spatiotemporal pattern of electrical activity that can be measured by observing the time-intervals between successive excitations of different regions of the cardiac tissue. Using biophysically detailed models of cardiac activity we show that the distribution of these time-intervals exhibit a systematic change in their skewness during such dynamical transitions. Further, the leading digits of the normalized intervals appear to fit Benford's law better at these transition points. This raises the possibility of using these observations to design a clinical indicator for identifying changes in the nature of arrhythmia. More importantly, our results reveal an intriguing relation between the changing skewness of a distribution and its agreement with Benford's law, both of which have been independently proposed earlier as indicators of regime shift in dynamical systems. PMID:26793114
Changes of skewness and sharpness of partially coherent decentered annular beams on propagation
NASA Astrophysics Data System (ADS)
Yang, Ting; Ji, Xiaoling; Li, Xiaoqing; Zhang, Hao; Wang, Tao
2016-01-01
Changes of skewness and sharpness of partially coherent decentered annular beams (PCDA beams) on propagation both in free space and in oceanic turbulence are studied. Based on the Wigner distribution function, the analytical expressions for the skewness parameter A and the kurtosis parameter K of PCDA beams are derived. The analytical expression for the oceanic turbulence parameter T‧ related to K is also derived, and characteristics of T‧ are examined. It is found that the behaviors of A and K in oceanic turbulence are quite different from those in free space. In free space, the mass of the intensity distribution may move from one side of the centroid position axis yc to another side at a certain propagation distance z0, and z0 is independent of the correlation parameter τ. The mass of the intensity distribution is concentrated on one side of yc on propagation only for a poorly coherent beam in free space, but it is always this situation for different value of τ when oceanic turbulence is not weak. In free space, it takes a leptokurtic profile in the far field, and a Gaussian profile appears only for a poorly coherent beam. However, in oceanic turbulence it always reaches a Gaussian profile for different value of τ in the far field.
Heat transfer in rotating serpentine passages with trips skewed to the flow
NASA Astrophysics Data System (ADS)
Johnson, B. V.; Wagner, J. H.; Steuber, G. D.; Yeh, F. C.
1992-06-01
Experiments were conducted to determine the effects of buoyancy and Coriolis forces on heat transfer in turbine blade internal coolant passages. The experiments were conducted with a large scale, multi-pass heat transfer model with both radially inward and outward flow. An analysis of the governing flow equations showed that four parameters influence the heat transfer in rotating passages: coolant-to-wall temperature, rotation number, Reynolds number, and radius-to-passage hydraulic diameter ratio. Results were correlated and compared to previous results from similar stationary and rotating models with smooth walls and with trip strips normal to the flow direction. It was concluded that (1) both Coriolis and buoyancy must be considered in turbine blade cooling designs with trip strips, (2) the effects of rotation are markedly different depending upon the flow direction, and (3) the heat transfer with skewed trip strips is less sensitive to buoyancy than the heat transfer models with either smooth or normal trips. Therefore, skewed trip strips rather than normal trip strips are recommended and geometry-specific tests are required for accurate design.
Chen, Jichun; Bryant, Mark A; Dent, James J; Sun, Yu; Desierto, Marie J; Young, Neal S
2015-12-01
A deletion of a telomerase RNA component (Terc(-/-)) in C57BL/6 (B6) mice resulted in hematopoietic lineage skewing with increased neutrophils and CD11b(+) myeloid cells and decreased red blood cells and CD45R(+) B lymphocytes when animals reach ages older than 12 months. There was no decline in bone marrow (BM) c-Kit(+)Sca-1(+)Lin(-) (KSL) cells in old Terc(-/-) mice, and the lineage skewing phenomenon was not transferred when BM cells from old Terc(-/-) donors were transplanted into young B6 recipients. Necropsy and histological examinations found minimal to no change in the lung, spleen and liver but detected severe epithelia degeneration, ulceration and infection in small and large intestines, leading to enteritis, typhlitis and colitis in old Terc(-/-) mice. In a mouse model of dextran-sulfate-sodium-induced typhlitis and colitis, development of intestinal pathology was associated with increases in neutrophils and CD11b(+) myeloid cells and a decrease in CD45R(+) B cells, similar to those observed in old Terc(-/-) mice. Treatment of 11-13 month old Terc(-/-) mice with antibiotic trimethoprim-sulfa water reduced neutrophils and myeloid cells and increased B lymphocytes in the blood, indicating that mitigation of intestinal infection and inflammation could alleviate hematological abnormalities in old Terc(-/-) animals. PMID:26523501
Chen, Jichun; Bryant, Mark A; Dent, James J; Sun, Yu; Desierto, Marie J; Young, Neal S
2015-12-01
A deletion of a telomerase RNA component (Terc(-/-)) in C57BL/6 (B6) mice resulted in hematopoietic lineage skewing with increased neutrophils and CD11b(+) myeloid cells and decreased red blood cells and CD45R(+) B lymphocytes when animals reach ages older than 12 months. There was no decline in bone marrow (BM) c-Kit(+)Sca-1(+)Lin(-) (KSL) cells in old Terc(-/-) mice, and the lineage skewing phenomenon was not transferred when BM cells from old Terc(-/-) donors were transplanted into young B6 recipients. Necropsy and histological examinations found minimal to no change in the lung, spleen and liver but detected severe epithelia degeneration, ulceration and infection in small and large intestines, leading to enteritis, typhlitis and colitis in old Terc(-/-) mice. In a mouse model of dextran-sulfate-sodium-induced typhlitis and colitis, development of intestinal pathology was associated with increases in neutrophils and CD11b(+) myeloid cells and a decrease in CD45R(+) B cells, similar to those observed in old Terc(-/-) mice. Treatment of 11-13 month old Terc(-/-) mice with antibiotic trimethoprim-sulfa water reduced neutrophils and myeloid cells and increased B lymphocytes in the blood, indicating that mitigation of intestinal infection and inflammation could alleviate hematological abnormalities in old Terc(-/-) animals.
Analyzing Fish Condition Factor Index Through Skew-Gaussian Information Theory Quantifiers
NASA Astrophysics Data System (ADS)
Contreras-Reyes, Javier E.
2016-06-01
Biological-fishery indicators have been widely studied. As such the condition factor (CF) index, which interprets the fatness level of a certain species based on length and weight, has been investigated, too. However, CF has been studied without considering its temporal features and distribution. In this paper, we analyze the CF time series via skew-gaussian distributions that consider the asymmetry produced by extreme events. This index is characterized by a threshold autoregressive model and corresponds to a stationary process depending on the shape parameter of the skew-gaussian distribution. Then we use the Jensen-Shannon (JS) distance to compare CF by length classes. This distance has mathematical advantages over other divergences such as Kullback-Leibler and Jeffrey’s, and the triangular inequality property. Our results are applied to a biological catalogue of anchovy (Engraulis ringens) from the northern coast of Chile, for the period 1990-2010 that consider monthly CF time series by length classes and sex. We find that for high values of shape parameter, JS distance tends to be more sensible to detect discrepancies than Jeffrey’s divergence. In addition, the body condition of male anchovies with higher lengths coincides with the ending of the moderate-strong El Niño event 91-92 and for both males and females, the smaller lengths coincide with the beginning of the strong El Niño event 97-98.
Skewness and kurtosis as indicators of non-Gaussianity in galactic foreground maps
Ben-David, Assaf; Jackson, Andrew D.; Hausegger, Sebastian von E-mail: s.vonhausegger@nbi.dk
2015-11-01
Observational cosmology is entering an era in which high precision will be required in both measurement and data analysis. Accuracy, however, can only be achieved with a thorough understanding of potential sources of contamination from foreground effects. Our primary focus will be on non-Gaussian effects in foregrounds. This issue will be crucial for coming experiments to determine B-mode polarization. We propose a novel method for investigating a data set in terms of skewness and kurtosis in locally defined regions that collectively cover the entire sky. The method is demonstrated on two sky maps: (i) the SMICA map of Cosmic Microwave Background fluctuations provided by the Planck Collaboration and (ii) a version of the Haslam map at 408 MHz that describes synchrotron radiation. We find that skewness and kurtosis can be evaluated in combination to reveal local physical information. In the present case, we demonstrate that the statistical properties of both maps in small local regions are predominantly Gaussian. This result was expected for the SMICA map. It is surprising that it also applies for the Haslam map given its evident large scale non-Gaussianity. The approach described here has a generality and flexibility that should make it useful in a variety of astrophysical and cosmological contexts.
Near and Far Field Acoustic Pressure Skewness in a Heated Supersonic Jet
NASA Astrophysics Data System (ADS)
Gutmark, Ephraim; Mora, Pablo; Kastner, Jeff; Heeb, Nick; Kailasanath, Kailas; Liu, Junhui; University of Cincinnati Collaboration; Naval Research Laboratory Collaboration
2012-11-01
The dominant component of turbulent mixing noise in high speed jets is the Mach wave radiation generated by large turbulent structures in the shear layer The Over-All Sound Pressure Level (OASPL) in the far field peaks in a direction near the Mach wave angle. ``Crackle'' is another important component of high speed jet noise. Crackle cannot be recognized in the spectrum of the acoustic pressure signal, but it appears in the temporal waveform of the pressure as sharply rising peaks. Skewness levels of the pressure and dP/dt have been used as a measure of crackle in high specific thrust engines and rockets. In this paper, we focus on recognizing a technique that identifies the impact of different test conditions on the near-field and far-field statistics of the pressure and dP/dt signals of a supersonic jet with a design Mach number of Md=1.5 produced by a C-D conical nozzle. Cold and hot jets, T0=300K and 600K, are tested at over, design, and under-expanded conditions, with NPRs=2.5, 3.671, 4.5, respectively. Second, Third and Forth order statistics are examined in the near and far fields. Rms, skewness and kurtosis intensity levels and propagation are better identified in the dP/dt than in the pressure signal. Statistics of the dP/dt demonstrate to be a better measure for crackle. Project funded by ONR grant.
Homoclinic snaking in plane Couette flow: bending, skewing and finite-size effects
NASA Astrophysics Data System (ADS)
Gibson, J. F.; Schneider, T. M.
2016-05-01
Invariant solutions of shear flows have recently been extended from spatially periodic solutions in minimal flow units to spatially localized solutions on extended domains. One set of spanwise-localized solutions of plane Couette flow exhibits homoclinic snaking, a process by which steady-state solutions grow additional structure smoothly at their fronts when continued parametrically. Homoclinic snaking is well understood mathematically in the context of the one-dimensional Swift-Hohenberg equation. Consequently, the snaking solutions of plane Couette flow form a promising connection between the largely phenomenological study of laminar-turbulent patterns in viscous shear flows and the mathematically well-developed field of pattern-formation theory. In this paper we present a numerical study of the snaking solutions, generalizing beyond the fixed streamwise wavelength of previous studies. We find a number of new solution features, including bending, skewing, and finite-size effects. We show that the finite-size effects result from the shift-reflect symmetry of the traveling wave and establish the parameter regions over which snaking occurs. A new winding solution of plane Couette flow is derived from a strongly skewed localized equilibrium.
Hasstrom, J.S.; Ermak, D.L.
1997-10-01
Vertical dispersion of material in the convective boundary layer, CBL, is dramatically different than in natural or stable boundary layers, as has been shown by field and laboratory experiments. Lagrangian stochastic modeling based on the Langevin equation has been shown to be useful for simulating vertical dispersion in the CBL. This modeling approach can account for the effects of the long Lagrangian time scales (associated with large-scale turbulent structures), skewed vertical velocity distributions, and vertically inhomogeneous turbulent properties found in the CBL. It has been recognized that simplified Langevin equation models that assume skewed but homogeneous velocity statistics can capture the important aspects of dispersion from sources the the CBL. The assumption of homogeneous turbulence has a significant practical advantage, specifically, longer time steps can be used in numerical simulations. In this paper, we compare two Langevin equations models that use the homogeneous turbulence assumption. We also compare and evaluate three reflection boundary conditions, the method for determining a new velocity for a particle that encounters a boundary. Model results are evaluated using data from Willis and Deardorff`s laboratory experiments for three different source heights.
Sardeshmukh, Prashant D.
2015-03-15
The probability distributions of large-scale atmospheric and oceanic variables are generally skewed and heavy-tailed. We argue that their distinctive departures from Gaussianity arise fundamentally from the fact that in a quadratically nonlinear system with a quadratic invariant, the coupling coefficients between system components are not constant but depend linearly on the system state in a distinctive way. In particular, the skewness arises from a tendency of the system trajectory to linger near states of weak coupling. We show that the salient features of the observed non-Gaussianity can be captured in the simplest such nonlinear 2-component system. If the system is stochastically forced and linearly damped, with one component damped much more strongly than the other, then the strongly damped fast component becomes effectively decoupled from the weakly damped slow component, and its impact on the slow component can be approximated as a stochastic noise forcing plus an augmented nonlinear damping. In the limit of large time-scale separation, the nonlinear augmentation of the damping becomes small, and the noise forcing can be approximated as an additive noise plus a correlated additive and multiplicative noise (CAM noise) forcing. Much of the diversity of observed large-scale atmospheric and oceanic probability distributions can be interpreted in this minimal framework.
Comment on "Universal relation between skewness and kurtosis in complex dynamics"
NASA Astrophysics Data System (ADS)
Celikoglu, Ahmet; Tirnakli, Ugur
2015-12-01
In a recent paper [M. Cristelli, A. Zaccaria, and L. Pietronero, Phys. Rev. E 85, 066108 (2012), 10.1103/PhysRevE.85.066108], the authors analyzed the relation between skewness and kurtosis for complex dynamical systems, and they identified two power-law regimes of non-Gaussianity, one of which scales with an exponent of 2 and the other with 4 /3 . They concluded that the observed relation is a universal fact in complex dynamical systems. In this Comment, we test the proposed universal relation between skewness and kurtosis with a large number of synthetic data, and we show that in fact it is not a universal relation and originates only due to the small number of data points in the datasets considered. The proposed relation is tested using a family of non-Gaussian distribution known as q -Gaussians. We show that this relation disappears for sufficiently large datasets provided that the fourth moment of the distribution is finite. We find that kurtosis saturates to a single value, which is of course different from the Gaussian case (K =3 ), as the number of data is increased, and this indicates that the kurtosis will converge to a finite single value if all moments of the distribution up to fourth are finite. The converged kurtosis value for the finite fourth-moment distributions and the number of data points needed to reach this value depend on the deviation of the original distribution from the Gaussian case.
Random sampling of skewed distributions implies Taylor's power law of fluctuation scaling.
Cohen, Joel E; Xu, Meng
2015-06-23
Taylor's law (TL), a widely verified quantitative pattern in ecology and other sciences, describes the variance in a species' population density (or other nonnegative quantity) as a power-law function of the mean density (or other nonnegative quantity): Approximately, variance = a(mean)(b), a > 0. Multiple mechanisms have been proposed to explain and interpret TL. Here, we show analytically that observations randomly sampled in blocks from any skewed frequency distribution with four finite moments give rise to TL. We do not claim this is the only way TL arises. We give approximate formulae for the TL parameters and their uncertainty. In computer simulations and an empirical example using basal area densities of red oak trees from Black Rock Forest, our formulae agree with the estimates obtained by least-squares regression. Our results show that the correlated sampling variation of the mean and variance of skewed distributions is statistically sufficient to explain TL under random sampling, without the intervention of any biological or behavioral mechanisms. This finding connects TL with the underlying distribution of population density (or other nonnegative quantity) and provides a baseline against which more complex mechanisms of TL can be compared. PMID:25852144
Diffuse holographic interferometric observation of shock wave reflection from a skewed wedge
NASA Astrophysics Data System (ADS)
Numata, D.; Ohtani, K.; Takayama, K.
2009-06-01
The pattern of shock wave reflection over a wedge is, in general, either a regular reflection or a Mach reflection, depending on wedge angles, shock wave Mach numbers, and specific heat ratios of gases. However, regular and Mach reflections can coexist, in particular, over a three-dimensional wedge surface, whose inclination angles locally vary normal to the direction of shock propagation. This paper reports a result of diffuse double exposure holographic interferometric observations of shock wave reflections over a skewed wedge surface placed in a 100 × 180 mm shock tube. The wedge consists of a straight generating line whose local inclination angle varies continuously from 30° to 60°. Painting its surface with fluorescent spray paint and irradiating its surface with a collimated object beam at a time interval of a few microseconds, we succeeded in visualizing three-dimensional shock reflection over the skewed wedge surface. Experiments were performed at shock Mach numbers, 1.55, 2.02, and 2.53 in air. From reconstructed holographic images, we estimated critical transition angles at these shock wave Mach numbers and found that these were very close to those over straight wedges. This is attributable to the flow three-dimensionality.
Fuel cell plates with skewed process channels for uniform distribution of stack compression load
Granata, Jr., Samuel J.; Woodle, Boyd M.
1989-01-01
An electrochemical fuel cell includes an anode electrode, a cathode electrode, an electrolyte matrix sandwiched between electrodes, and a pair of plates above and below the electrodes. The plate above the electrodes has a lower surface with a first group of process gas flow channels formed thereon and the plate below the electrodes has an upper surface with a second group of process gas flow channels formed thereon. The channels of each group extend generally parallel to one another. The improvement comprises the process gas flow channels on the lower surface of the plate above the anode electrode and the process gas flow channels on the upper surface of the plate below the cathode electrode being skewed in opposite directions such that contact areas of the surfaces of the plates through the electrodes are formed in crisscross arrangements. Also, the plates have at least one groove in areas of the surfaces thereof where the channels are absent for holding process gas and increasing electrochemical activity of the fuel cell. The groove in each plate surface intersects with the process channels therein. Also, the opposite surfaces of a bipolar plate for a fuel cell contain first and second arrangements of process gas flow channels in the respective surfaces which are skewed the same amount in opposite directions relative to the longitudinal centerline of the plate.
Deconstructing risk: Separable encoding of variance and skewness in the brain
Symmonds, Mkael; Wright, Nicholas D.; Bach, Dominik R.; Dolan, Raymond J.
2011-01-01
Risky choice entails a need to appraise all possible outcomes and integrate this information with individual risk preference. Risk is frequently quantified solely by statistical variance of outcomes, but here we provide evidence that individuals’ choice behaviour is sensitive to both dispersion (variance) and asymmetry (skewness) of outcomes. Using a novel behavioural paradigm in humans, we independently manipulated these ‘summary statistics’ while scanning subjects with fMRI. We show that a behavioural sensitivity to variance and skewness is mirrored in neuroanatomically dissociable representations of these quantities, with parietal cortex showing sensitivity to the former and prefrontal cortex and ventral striatum to the latter. Furthermore, integration of these objective risk metrics with subjective risk preference is expressed in a subject-specific coupling between neural activity and choice behaviour in anterior insula. Our findings show that risk is neither monolithic from a behavioural nor neural perspective and its decomposition is evident both in distinct behavioural preferences and in segregated underlying brain representations. PMID:21763444
Heat transfer in rotating serpentine passages with trips skewed to the flow
NASA Technical Reports Server (NTRS)
Johnson, B. V.; Wagner, J. H.; Steuber, G. D.; Yeh, F. C.
1992-01-01
Experiments were conducted to determine the effects of buoyancy and Coriolis forces on heat transfer in turbine blade internal coolant passages. The experiments were conducted with a large scale, multi-pass heat transfer model with both radially inward and outward flow. An analysis of the governing flow equations showed that four parameters influence the heat transfer in rotating passages: coolant-to-wall temperature, rotation number, Reynolds number, and radius-to-passage hydraulic diameter ratio. Results were correlated and compared to previous results from similar stationary and rotating models with smooth walls and with trip strips normal to the flow direction. It was concluded that (1) both Coriolis and buoyancy must be considered in turbine blade cooling designs with trip strips, (2) the effects of rotation are markedly different depending upon the flow direction, and (3) the heat transfer with skewed trip strips is less sensitive to buoyancy than the heat transfer models with either smooth or normal trips. Therefore, skewed trip strips rather than normal trip strips are recommended and geometry-specific tests are required for accurate design.
Maximum Parsimony and the Skewness Test: A Simulation Study of the Limits of Applicability.
Määttä, Jussi; Roos, Teemu
2016-01-01
The maximum parsimony (MP) method for inferring phylogenies is widely used, but little is known about its limitations in non-asymptotic situations. This study employs large-scale computations with simulated phylogenetic data to estimate the probability that MP succeeds in finding the true phylogeny for up to twelve taxa and 256 characters. The set of candidate phylogenies are taken to be unrooted binary trees; for each simulated data set, the tree lengths of all (2n - 5)!! candidates are computed to evaluate quantities related to the performance of MP, such as the probability of finding the true phylogeny, the probability that the tree with the shortest length is unique, the probability that the true phylogeny has the shortest tree length, and the expected inverse of the number of trees sharing the shortest length. The tree length distributions are also used to evaluate and extend the skewness test of Hillis for distinguishing between random and phylogenetic data. The results indicate, for example, that the critical point after which MP achieves a success probability of at least 0.9 is roughly around 128 characters. The skewness test is found to perform well on simulated data and the study extends its scope to up to twelve taxa. PMID:27035667
Jaffé, Rodolfo; Garcia-Gonzalez, Francisco; den Boer, Susanne P A; Simmons, Leigh W; Baer, Boris
2012-12-01
Monogamy results in high genetic relatedness among offspring and thus it is generally assumed to be favored by kin selection. Female multiple mating (polyandry) has nevertheless evolved several times in the social Hymenoptera (ants, bees, and wasps), and a substantial amount of work has been conducted to understand its costs and benefits. Relatedness and inclusive fitness benefits are, however, not only influenced by queen mating frequency but also by paternity skew, which is a quantitative measure of paternity biases among the offspring of polyandrous females. We performed a large-scale phylogenetic analysis of paternity skew across polyandrous social Hymenoptera. We found a general and significant negative association between paternity frequency and paternity skew. High paternity skew, which increases relatedness among colony members and thus maximizes inclusive fitness gains, characterized species with low paternity frequency. However, species with highly polyandrous queens had low paternity skew, with paternity equalized among potential sires. Equal paternity shares among fathers are expected to maximize fitness benefits derived from genetic diversity among offspring. We discuss the potential for postcopulatory sexual selection to influence patterns of paternity in social insects, and suggest that sexual selection may have played a key, yet overlooked role in social evolution.
James, Patrick M A; Janes, Jasmine K; Roe, Amanda D; Cooke, Barry J
2016-08-01
Through their influence on effective population sizes, sex ratio skew affects population dynamics. We examined spatial variation in female-biased sex ratios in the mountain pine beetle (Dendroctonus ponderosae Hopkins) outbreak in western Canada to better understand how environmental context affects sex ratio skew. Our specific objectives were to: 1) characterize spatial variation in mountain pine beetle sex ratio; 2) test previously asserted hypotheses that beetle sex ratio varies with tree diameter and year in outbreak; and 3) develop predictive models of sex ratio skew for larval and adult populations. Using logistic regression, we modeled the probability that an individual beetle (n = 2,369) was female as a function of multiple environmental variables across 34 stands in British Columbia and Alberta, Canada. We identified a consistent female-biased sex ratio with significantly greater skew in adults (2:1, n = 713) than in larvae (1.76:1, n = 1,643). We found that the proportion of larval females increased with decreasing tree size and with outbreak age. However, adults did not respond to tree size and larvae did not respond to outbreak age. Predictive models differed between larvae and adults. All identified models perform well and included predictors related to weather, tree diameter, and year in outbreak. Female-biased sex ratios appear to originate from differential male mortality during development rather than from sex-biased oviposition, suggesting sex ratio skew is not the cause of outbreaks, but rather a consequence. PMID:27209334
Gentilini, Davide; Garagnani, Paolo; Pisoni, Serena; Bacalini, Maria Giulia; Calzari, Luciano; Mari, Daniela; Vitale, Giovanni; Franceschi, Claudio; Di Blasio, Anna Maria
2015-08-01
In this study we applied a new analytical strategy to investigate the relations between stochastic epigenetic mutations (SEMs) and aging. We analysed methylation levels through the Infinium HumanMethylation27 and HumanMethylation450 BeadChips in a population of 178 subjects ranging from 3 to 106 years. For each CpG probe, epimutated subjects were identified as the extreme outliers with methylation level exceeding three times interquartile ranges the first quartile (Q1-(3 x IQR)) or the third quartile (Q3+(3 x IQR)). We demonstrated that the number of SEMs was low in childhood and increased exponentially during aging. Using the HUMARA method, skewing of X chromosome inactivation (XCI) was evaluated in heterozygotes women. Multivariate analysis indicated a significant correlation between log(SEMs) and degree of XCI skewing after adjustment for age (β = 0.41; confidence interval: 0.14, 0.68; p-value = 0.0053). The PATH analysis tested the complete model containing the variables: skewing of XCI, age, log(SEMs) and overall CpG methylation. After adjusting for the number of epimutations we failed to confirm the well reported correlation between skewing of XCI and aging. This evidence might suggest that the known correlation between XCI skewing and aging could not be a direct association but mediated by the number of SEMs.
James, Patrick M A; Janes, Jasmine K; Roe, Amanda D; Cooke, Barry J
2016-08-01
Through their influence on effective population sizes, sex ratio skew affects population dynamics. We examined spatial variation in female-biased sex ratios in the mountain pine beetle (Dendroctonus ponderosae Hopkins) outbreak in western Canada to better understand how environmental context affects sex ratio skew. Our specific objectives were to: 1) characterize spatial variation in mountain pine beetle sex ratio; 2) test previously asserted hypotheses that beetle sex ratio varies with tree diameter and year in outbreak; and 3) develop predictive models of sex ratio skew for larval and adult populations. Using logistic regression, we modeled the probability that an individual beetle (n = 2,369) was female as a function of multiple environmental variables across 34 stands in British Columbia and Alberta, Canada. We identified a consistent female-biased sex ratio with significantly greater skew in adults (2:1, n = 713) than in larvae (1.76:1, n = 1,643). We found that the proportion of larval females increased with decreasing tree size and with outbreak age. However, adults did not respond to tree size and larvae did not respond to outbreak age. Predictive models differed between larvae and adults. All identified models perform well and included predictors related to weather, tree diameter, and year in outbreak. Female-biased sex ratios appear to originate from differential male mortality during development rather than from sex-biased oviposition, suggesting sex ratio skew is not the cause of outbreaks, but rather a consequence.
Foundation Depth for Bridge Piers
NASA Astrophysics Data System (ADS)
Veerappadevaru, G.; Gangadharaiah, T.; Jagadeesh, T. R.
2013-09-01
The safety of bridge piers built in rivers having the bed is one of the prime aspects in the study of scouring process around bridge piers. The stability of bridge piers depends on the depth of foundation provided below maximum scour level. The stability analysis of bridge piers is carried based on moment of forces acting on the caisson pier when the pier slides and tilts slightly in downstream from its position. The experiments are conducted for three pier shapes on two sediment beds and for different flow conditions. The curves indicating the stability limits are compared with Lacey's recommendations which are used in present day practice in India. The analysis presented here indicates that the Lacey's recommendation for railway bridges is safe and for some cases of the road bridges depends on grip length, angle of tilt and weight of caisson.
Wessendorf, K.O.
1998-07-01
This paper describes the Active-Bridge Oscillator (ABO), a new concept in high-stability oscillator design. The ABO is ab ridge-type oscillator design that is easly to design and overcomes many of the operational and design difficulties associated with standard bridge oscillator designs. The ABO will oscillate with a very stable output amplitude over a wide range of operating conditions without the use of an automatic-level-control (ALC). A standard bridge oscillator design requires an ALC to maintain the desired amplitude of oscillation. for this and other reasons, bridge oscilaltors are not used in mainstream designs. Bridge oscillators are generally relegated to relatively low-volume, high-performance applications. The Colpitts and Pierce designs are the most popular oscillators but are typically less stable than a bridge-type oscillator.
Morphological aspects of myocardial bridges.
Lujinović, Almira; Kulenović, Amela; Kapur, Eldan; Gojak, Refet
2013-11-01
Although some myocardial bridges can be asymptomatic, their presence often causes coronary disease either through direct compression of the "tunnel" segment or through stimulation and accelerated development of atherosclerosis in the segment proximally to the myocardial bridge. The studied material contained 30 human hearts received from the Department of Anatomy. The hearts were preserved 3 to 5 days in 10% formalin solution. Thereafter, the fatty tissue was removed and arterial blood vessels prepared by careful dissection with special reference to the presence of the myocardial bridges. Length and thickness of the bridges were measured by the precise electronic caliper. The angle between the myocardial bridge fibre axis and other axis of the crossed blood vessel was measured by a goniometer. The presence of the bridges was confirmed in 53.33% of the researched material, most frequently (43.33%) above the anterior interventricular branch. The mean length of the bridges was 14.64 ± 9.03 mm and the mean thickness was 1.23 ± 1.32 mm. Myocardial bridge fibres pass over the descending blood vessel at the angle of 10-90 degrees. The results obtained on a limited sample suggest that the muscular index of myocardial bridge is the highest for bridges located on RIA, but that the difference is not significant in relation to bridges located on other branches. The results obtained suggest that bridges located on other branches, not only those on RIA, could have a great contractive power and, consequently, a great compressive force, which would be exerted on the wall of a crossed blood vessel.
Webb, Michele
2016-01-01
The view from the top of Hoover Dam looking south over the Colorado River was breathtaking! My friend and I stood there in silence, taking it all in. I had visited Hoover Dam on many occasions, but this visit was the first time I had seen the arch bridge that carries US Route 93 over the river and joins Nevada and Arizona states. It was a beautiful day, the temperature was perfect, and there was a slight breeze coming from Lake Mead behind us as we took in the view. PMID:27556855
Nasal Bridge Intramuscular Hemangioma
Hamir Basah, Zulkifli; Ramza Ramli, Ramiza; Gayadh, Maha Khadum; Mutum, Samarendra Singh
2015-01-01
Intramuscular haemangioma (IMH) is a benign mesenchymal tumour. It appears as a deep, nontender mass within the soft tissue, particularly in the extremities. This tumour may not be obvious on clinical examination. Head and neck IMHs represent only 13.5% of the total IMHs. The most common site for a head and neck IMH is the masseter muscle, followed by trapezius, sternocleidomastoid, and very rarely temporalis muscle. We present a patient with left nasal bridge swelling which was excised and histologically confirmed as intramuscular hemangioma. PMID:25709848
Lumia, Richard; Baevsky, Yvonne H.
2000-01-01
Flood-frequency relations that are developed by fitting the logarithms of annual peak discharges to a Pearson Type-III distribution are sensitive to skew coefficients. Estimates of population skew for a site are improved when computed from the weighted average of (1) the sample (station) skew, and (2) an unbiased, generalized skew estimate. A weighting technique based on the number of years of record at each of 226 sites was used to develop a contour map of unbiased, generalized skew coefficients for New York. An attempt was made to group (regionalize) the station skew coefficients into five hydrologically similar areas of New York, but the statewide version proved to be as accurate as the regionalized version and therefore was adopted as the final generalized skew-coefficient map for New York. An error analysis showed the statewide contour map to have lower MSE?s (mean square errors) than those computed from (1) the five regional skewcoefficient contour maps, (2) a previously used (1982) nationwide skew coefficient map, and (3) the weighted mean of skew coefficients for sites within each of five hydrologically uniform, but distinct areas of New York.
33 CFR 115.40 - Bridge repairs.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Bridge repairs. 115.40 Section 115.40 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LOCATIONS AND CLEARANCES; ADMINISTRATIVE PROCEDURES § 115.40 Bridge repairs. Repairs to a bridge which...
33 CFR 115.40 - Bridge repairs.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Bridge repairs. 115.40 Section 115.40 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LOCATIONS AND CLEARANCES; ADMINISTRATIVE PROCEDURES § 115.40 Bridge repairs. Repairs to a bridge which...
33 CFR 115.40 - Bridge repairs.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Bridge repairs. 115.40 Section 115.40 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LOCATIONS AND CLEARANCES; ADMINISTRATIVE PROCEDURES § 115.40 Bridge repairs. Repairs to a bridge which...
33 CFR 115.40 - Bridge repairs.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Bridge repairs. 115.40 Section 115.40 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LOCATIONS AND CLEARANCES; ADMINISTRATIVE PROCEDURES § 115.40 Bridge repairs. Repairs to a bridge which...
33 CFR 115.40 - Bridge repairs.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Bridge repairs. 115.40 Section 115.40 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LOCATIONS AND CLEARANCES; ADMINISTRATIVE PROCEDURES § 115.40 Bridge repairs. Repairs to a bridge which...
16. Little Hell Gate Bridge with Big Hell Gate Bridge ...
16. Little Hell Gate Bridge with Big Hell Gate Bridge in background. Wards Island, New York Co., NY. Sec. 4207, MP 8.02. - Northeast Railroad Corridor, Amtrak Route between New Jersey/New York & New York/Connecticut State Lines, New York County, NY
20. Bronx Kill Bridge with Hell Gate Bridge in background. ...
20. Bronx Kill Bridge with Hell Gate Bridge in background. Randalls Island, New York Co., NY. Sec. 4207, MP 8.54. - Northeast Railroad Corridor, Amtrak Route between New Jersey/New York & New York/Connecticut State Lines, New York County, NY
25. White Plains Road Bridge in foreground; Unionport Road Bridge ...
25. White Plains Road Bridge in foreground; Unionport Road Bridge in background. Van Nest, Bronx Co., NY. Sec. 4207, MP 12.75./78. - Northeast Railroad Corridor, Amtrak Route between New Jersey/New York & New York/Connecticut State Lines, New York County, NY
NASA Astrophysics Data System (ADS)
Obaya, Rafael; Sanz, Ana M.
2016-10-01
We determine sufficient conditions for uniform and strict persistence in the case of skew-product semiflows generated by solutions of non-autonomous families of cooperative systems of ODEs or delay FDEs in terms of the principal spectrums of some associated linear skew-product semiflows which admit a continuous separation. Our conditions are also necessary in the linear case. We apply our results to a noncooperative almost periodic Nicholson system with a patch structure, whose persistence turns out to be equivalent to the persistence of the linearized system along the null solution.
47 CFR 80.1007 - Bridge-to-bridge radiotelephone installation.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 47 Telecommunication 5 2014-10-01 2014-10-01 false Bridge-to-bridge radiotelephone installation. 80.1007 Section 80.1007 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND... Bridge-to-Bridge Act § 80.1007 Bridge-to-bridge radiotelephone installation. Use of the...
47 CFR 80.163 - Operator requirements of the Bridge-to-Bridge Act.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 47 Telecommunication 5 2012-10-01 2012-10-01 false Operator requirements of the Bridge-to-Bridge... Requirements § 80.163 Operator requirements of the Bridge-to-Bridge Act. Each ship subject to the Bridge-to-Bridge Act must have on board a radio operator who holds a restricted radiotelephone operator permit...
47 CFR 80.163 - Operator requirements of the Bridge-to-Bridge Act.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 47 Telecommunication 5 2014-10-01 2014-10-01 false Operator requirements of the Bridge-to-Bridge... Requirements § 80.163 Operator requirements of the Bridge-to-Bridge Act. Each ship subject to the Bridge-to-Bridge Act must have on board a radio operator who holds a restricted radiotelephone operator permit...
47 CFR 80.331 - Bridge-to-bridge communication procedure.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 47 Telecommunication 5 2011-10-01 2011-10-01 false Bridge-to-bridge communication procedure. 80..., Alarm, Urgency and Safety Procedures § 80.331 Bridge-to-bridge communication procedure. (a) Vessels subject to the Bridge-to-Bridge Act transmitting on the designated navigational frequency must...
47 CFR 80.163 - Operator requirements of the Bridge-to-Bridge Act.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 47 Telecommunication 5 2013-10-01 2013-10-01 false Operator requirements of the Bridge-to-Bridge... Requirements § 80.163 Operator requirements of the Bridge-to-Bridge Act. Each ship subject to the Bridge-to-Bridge Act must have on board a radio operator who holds a restricted radiotelephone operator permit...
47 CFR 80.1007 - Bridge-to-bridge radiotelephone installation.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 47 Telecommunication 5 2012-10-01 2012-10-01 false Bridge-to-bridge radiotelephone installation. 80.1007 Section 80.1007 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND... Bridge-to-Bridge Act § 80.1007 Bridge-to-bridge radiotelephone installation. Use of the...
47 CFR 80.331 - Bridge-to-bridge communication procedure.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 47 Telecommunication 5 2013-10-01 2013-10-01 false Bridge-to-bridge communication procedure. 80..., Alarm, Urgency and Safety Procedures § 80.331 Bridge-to-bridge communication procedure. (a) Vessels subject to the Bridge-to-Bridge Act transmitting on the designated navigational frequency must...
47 CFR 80.1007 - Bridge-to-bridge radiotelephone installation.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 47 Telecommunication 5 2010-10-01 2010-10-01 false Bridge-to-bridge radiotelephone installation. 80.1007 Section 80.1007 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND... Bridge-to-Bridge Act § 80.1007 Bridge-to-bridge radiotelephone installation. Use of the...
47 CFR 80.331 - Bridge-to-bridge communication procedure.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 47 Telecommunication 5 2012-10-01 2012-10-01 false Bridge-to-bridge communication procedure. 80..., Alarm, Urgency and Safety Procedures § 80.331 Bridge-to-bridge communication procedure. (a) Vessels subject to the Bridge-to-Bridge Act transmitting on the designated navigational frequency must...
47 CFR 80.331 - Bridge-to-bridge communication procedure.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 47 Telecommunication 5 2014-10-01 2014-10-01 false Bridge-to-bridge communication procedure. 80..., Alarm, Urgency and Safety Procedures § 80.331 Bridge-to-bridge communication procedure. (a) Vessels subject to the Bridge-to-Bridge Act transmitting on the designated navigational frequency must...
47 CFR 80.163 - Operator requirements of the Bridge-to-Bridge Act.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 47 Telecommunication 5 2010-10-01 2010-10-01 false Operator requirements of the Bridge-to-Bridge... Requirements § 80.163 Operator requirements of the Bridge-to-Bridge Act. Each ship subject to the Bridge-to-Bridge Act must have on board a radio operator who holds a restricted radiotelephone operator permit...
47 CFR 80.331 - Bridge-to-bridge communication procedure.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 47 Telecommunication 5 2010-10-01 2010-10-01 false Bridge-to-bridge communication procedure. 80..., Alarm, Urgency and Safety Procedures § 80.331 Bridge-to-bridge communication procedure. (a) Vessels subject to the Bridge-to-Bridge Act transmitting on the designated navigational frequency must...
47 CFR 80.1007 - Bridge-to-bridge radiotelephone installation.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 47 Telecommunication 5 2013-10-01 2013-10-01 false Bridge-to-bridge radiotelephone installation. 80.1007 Section 80.1007 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND... Bridge-to-Bridge Act § 80.1007 Bridge-to-bridge radiotelephone installation. Use of the...
47 CFR 80.1007 - Bridge-to-bridge radiotelephone installation.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 47 Telecommunication 5 2011-10-01 2011-10-01 false Bridge-to-bridge radiotelephone installation. 80.1007 Section 80.1007 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND... Bridge-to-Bridge Act § 80.1007 Bridge-to-bridge radiotelephone installation. Use of the...
47 CFR 80.163 - Operator requirements of the Bridge-to-Bridge Act.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 47 Telecommunication 5 2011-10-01 2011-10-01 false Operator requirements of the Bridge-to-Bridge... Requirements § 80.163 Operator requirements of the Bridge-to-Bridge Act. Each ship subject to the Bridge-to-Bridge Act must have on board a radio operator who holds a restricted radiotelephone operator permit...
Random X-chromosome inactivation: skewing lessons for mice and men.
Clerc, Philippe; Avner, Philip
2006-06-01
The mammalian X-chromosome exists in two flavors, active and inactive, in each cell of the adult female. This phenomenon originates from the process of random choice occurring early in development in a small number of progenitor cells in which the decision is made to inactivate either one or the other X chromosome on a cell-autonomous basis. Once made, this initial decision is irreversible, although exceptions exist in specific chromosomal territories and cell lineages. Recent findings implicate various factors, including non-coding RNAs and chromatin modification complexes, as effectors in the initiation and maintenance of X-chromosome inactivation. The functional redundancy of such factors almost certainly plays an important role in the stability of the inactive X. Studying skewing or bias opens an important opportunity for understanding facets of the random choice process.
Foldnes, Njål; Olsson, Ulf Henning
2016-01-01
We present and investigate a simple way to generate nonnormal data using linear combinations of independent generator (IG) variables. The simulated data have prespecified univariate skewness and kurtosis and a given covariance matrix. In contrast to the widely used Vale-Maurelli (VM) transform, the obtained data are shown to have a non-Gaussian copula. We analytically obtain asymptotic robustness conditions for the IG distribution. We show empirically that popular test statistics in covariance analysis tend to reject true models more often under the IG transform than under the VM transform. This implies that overly optimistic evaluations of estimators and fit statistics in covariance structure analysis may be tempered by including the IG transform for nonnormal data generation. We provide an implementation of the IG transform in the R environment.
Extrinsic Spin Hall Effect Induced by Resonant Skew Scattering in Graphene
NASA Astrophysics Data System (ADS)
Ferreira, Aires; Rappoport, Tatiana G.; Cazalilla, Miguel A.; Castro Neto, A. H.
2015-03-01
We show that the extrinsic spin Hall effect can be engineered in monolayer graphene by decoration with small doses of adatoms, molecules, or nanoparticles originating local spin-orbit perturbations. The analysis of the single impurity scattering problem shows that intrinsic and Rashba spin-orbit local couplings enhance the spin Hall effect via skew scattering of charge carriers in the resonant regime. The solution of the transport equations for a random ensemble of spin-orbit impurities reveals that giant spin Hall currents are within the reach of the current state of the art in device fabrication. The spin Hall effect is robust with respect to thermal fluctuations and disorder averaging. The author acknowledges support from the National Research Foundation-Competitive Research Programme through Grant No. R-144-000-295-281.
The Modified Concorde Position with an Intraoperative Skew Head Rotation: Technical Note
TAKASUNA, Hiroshi; TANAKA, Yuichiro
2015-01-01
The Concorde position was developed to approach pineal and cerebellar lesions with a midline suboccipital craniotomy. The neutral head position is needed to divide the occipital muscles symmetrically. The patient’s head is tilted to the right and the face is turned to the right for the microscopic procedure to keep the midline of the patient’s head axis straight in the surgical field for comfortable and accurate surgical manipulation. However, intraoperative repositioning of the patient’s head is somewhat difficult to release the holding arm of the Sugita head holder in the original method. We found that a skew head rotation by fixing the head asymmetrically in the Sugita head holder is very quick and convenient to obtain the optimal head position both for a craniotomy and a microscopic procedure. PMID:26226983
The Modified Concorde Position with an Intraoperative Skew Head Rotation: Technical Note.
Takasuna, Hiroshi; Tanaka, Yuichiro
2015-01-01
The Concorde position was developed to approach pineal and cerebellar lesions with a midline suboccipital craniotomy. The neutral head position is needed to divide the occipital muscles symmetrically. The patient's head is tilted to the right and the face is turned to the right for the microscopic procedure to keep the midline of the patient's head axis straight in the surgical field for comfortable and accurate surgical manipulation. However, intraoperative repositioning of the patient's head is somewhat difficult to release the holding arm of the Sugita head holder in the original method. We found that a skew head rotation by fixing the head asymmetrically in the Sugita head holder is very quick and convenient to obtain the optimal head position both for a craniotomy and a microscopic procedure.
Two generalized Wigner-Yanase skew information and their uncertainty relations
NASA Astrophysics Data System (ADS)
Chen, Zheng-Li; Liang, Li-Li; Li, Hao-Jing; Wang, Wen-Hua
2016-09-01
In this paper, we first define two generalized Wigner-Yanase skew information |K_{ρ ,α }|(A) and |L_{ρ ,α }|(A) for any non-Hermitian Hilbert-Schmidt operator A and a density operator ρ on a Hilbert space H and discuss some properties of them, respectively. We also introduce two related quantities |S_{ρ ,α }|(A) and |T_{ρ ,α }|(A) . Then, we establish two uncertainty relations in terms of |W_{ρ ,α }|(A) and |widetilde{W}_{ρ ,α }|(A) , which read |W_{ρ ,α }|(A)|W_{ρ ,α }|(B)≥ 1/4| {tr}( [ ρ ^{α }+ρ ^{1-α }/2 ] 2[A,B]0) | 2, √{|widetilde{W}_{ρ ,α }|(A)| widetilde{W}_{ρ ,α }|(B)}≥ 1/4 | {tr}( ρ ^{2α }[A,B]0) {tr} ( ρ ^{2(1-α )}[A,B]0) | .
Low paternity skew and the influence of maternal kin in an egalitarian, patrilocal primate
Strier, Karen B.; Chaves, Paulo B.; Mendes, Sérgio L.; Fagundes, Valéria; Di Fiore, Anthony
2011-01-01
Levels of reproductive skew vary in wild primates living in multimale groups depending on the degree to which high-ranking males monopolize access to females. Still, the factors affecting paternity in egalitarian societies remain unexplored. We combine unique behavioral, life history, and genetic data to evaluate the distribution of paternity in the northern muriqui (Brachyteles hypoxanthus), a species known for its affiliative, nonhierarchical relationships. We genotyped 67 individuals (22 infants born over a 3-y period, their 21 mothers, and all 24 possible sires) at 17 microsatellite marker loci and assigned paternity to all infants. None of the 13 fathers were close maternal relatives of females with which they sired infants, and the most successful male sired a much lower percentage of infants (18%) than reported for the most successful males in other species. Our findings of inbreeding avoidance and low male reproductive skew are consistent with the muriqui's observed social and sexual behavior, but the long delay (≥2.08 y) between the onset of male sexual behavior and the age at which males first sire young is unexpected. The allocation of paternity implicates individual male life histories and access to maternal kin as key factors influencing variation in paternal—and grandmaternal—fitness. The apparent importance of lifelong maternal investment in coresident sons resonates with other recent examinations of maternal influences on offspring reproduction. This importance also extends the implications of the “grandmother hypothesis” in human evolution to include the possible influence of mothers and other maternal kin on male reproductive success in patrilocal societies. PMID:22065786
A missing model in reproductive skew theory: the bordered tug-of-war.
Reeve, Hudson Kern; Shen, Sheng-Feng
2006-05-30
Models of reproductive skew can be classified into two groups: transactional models, in which group members yield shares of reproduction to each other in return for cooperation, and tug-of-war models, in which group members invest group resources in a tug-of-war over their respective reproductive shares. We synthesize these two models to yield a "bordered tug-of-war" model in which the internal tug-of-war is limited ("bordered") by the requirement that group members must achieve a certain amount of reproduction lest they pursue a noncooperative option leading to group breakup. Previous attempts to synthesize these two models did not allow for the fact that the tug-of-war will affect group output, which in turn feeds back on the reproductive payments required by group members to remain cooperative. The bordered tug-of-war model, which does not assume complete reproductive control by any individual and allows for conflict within groups, predicts that the degree of within-group selfishness will increase as the noncooperative options become less attractive, e.g., as ecological constraints on solitary breeding increase. When the noncooperative option involves fighting for the group resource (e.g., territory) and leaving if the fight is lost, the subordinate's overall share of reproduction is predicted to be independent of its relatedness to the dominant and to increase the greater its probability of winning the fight, the less the value of the territory, and the greater its personal payoff for leaving. The unique predictions of the bordered tug-of-war model may fit skew data from a number of species, including meerkats, lions, and wood mice.
Ultra-High Energy Cosmic Rays: Composition, Early Air Shower Interactions, and Xmax Skewness
NASA Astrophysics Data System (ADS)
Stapleton, James
The composition of Ultra-High Energy Cosmic Rays (UHECRs) is still not completely understood, and must be inferred from Extended Air Shower (EAS), particle cascades which they initiate upon entering the atmosphere. The atmospheric depth at which the shower contains the maximum number of particles ( Xmax) is the most composition-sensitive property of the air shower, but its interpretation is hindered by intrinsic statistical fluctuations in EAS development which cause distinct compositions to produce overlapping Xmax distributions as well as our limited knowledge at these energies of hadronic physics which strongly impacts the Xmax distribution's shape. These issues ultimately necessitate a variety of complementary approaches to interpreting UHECR composition from Xmax data. The current work advances these approaches by connecting X max skewness to the uncertainties above. The study of X max has historically focused only on the mean and standard deviation of its distribution, but skewness is shown here to be strongly related to both the statistical fluctuations in EAS development as well as the least-understood hadronic cross-sections in the air shower. This leads into a treatment of the Exponentially-Modified Gaussian (EMG) distribution, whose little-known properties make it very useful for Xmax analysis and for data analysis in general. A powerful method emerges which uses only descriptive statistics in a robust check for energy-dependent changes in UHECR mass or EAS development. The application of these analyses to X max data provides tantalizing clues concerning issues of critical importance, such as the relationship between Xmax and the 'ankle' break in the UHECR energy spectrum, or the inferred properties of the UHECR mass distribution and its strong dependence on hadronic model systematics.
Th1-skewed tissue responses to a mycolyl glycolipid in mycobacteria-infected rhesus macaques
Morita, Daisuke; Miyamoto, Ayumi; Hattori, Yuki; Komori, Takaya; Nakamura, Takashi; Igarashi, Tatsuhiko; Harashima, Hideyoshi; Sugita, Masahiko
2013-11-08
Highlights: •Glucose monomycolate (GMM) is a marker glycolipid for active tuberculosis. •Tissue responses to GMM involved up-regulation of Th1-attracting chemokines. •Th1-skewed local responses were mounted at the GMM-injected tissue. -- Abstract: Trehalose 6,6′-dimycolate (TDM) is a major glycolipid of the cell wall of mycobacteria with remarkable adjuvant functions. To avoid detection by the host innate immune system, invading mycobacteria down-regulate the expression of TDM by utilizing host-derived glucose as a competitive substrate for their mycolyltransferases; however, this enzymatic reaction results in the concomitant biosynthesis of glucose monomycolate (GMM) which is recognized by the acquired immune system. GMM-specific, CD1-restricted T cell responses have been detected in the peripheral blood of infected human subjects and monkeys as well as in secondary lymphoid organs of small animals, such as guinea pigs and human CD1-transgenic mice. Nevertheless, it remains to be determined how tissues respond at the site where GMM is produced. Here we found that rhesus macaques vaccinated with Mycobacterium bovis bacillus Calmette–Guerin mounted a chemokine response in GMM-challenged skin that was favorable for recruiting T helper (Th)1 T cells. Indeed, the expression of interferon-γ, but not Th2 or Th17 cytokines, was prominent in the GMM-injected tissue. The GMM-elicited tissue response was also associated with the expression of monocyte/macrophage-attracting CC chemokines, such as CCL2, CCL4 and CCL8. Furthermore, the skin response to GMM involved the up-regulated expression of granulysin and perforin. Given that GMM is produced primarily by pathogenic mycobacteria proliferating within the host, the Th1-skewed tissue response to GMM may function efficiently at the site of infection.
A missing model in reproductive skew theory: the bordered tug-of-war.
Reeve, Hudson Kern; Shen, Sheng-Feng
2006-05-30
Models of reproductive skew can be classified into two groups: transactional models, in which group members yield shares of reproduction to each other in return for cooperation, and tug-of-war models, in which group members invest group resources in a tug-of-war over their respective reproductive shares. We synthesize these two models to yield a "bordered tug-of-war" model in which the internal tug-of-war is limited ("bordered") by the requirement that group members must achieve a certain amount of reproduction lest they pursue a noncooperative option leading to group breakup. Previous attempts to synthesize these two models did not allow for the fact that the tug-of-war will affect group output, which in turn feeds back on the reproductive payments required by group members to remain cooperative. The bordered tug-of-war model, which does not assume complete reproductive control by any individual and allows for conflict within groups, predicts that the degree of within-group selfishness will increase as the noncooperative options become less attractive, e.g., as ecological constraints on solitary breeding increase. When the noncooperative option involves fighting for the group resource (e.g., territory) and leaving if the fight is lost, the subordinate's overall share of reproduction is predicted to be independent of its relatedness to the dominant and to increase the greater its probability of winning the fight, the less the value of the territory, and the greater its personal payoff for leaving. The unique predictions of the bordered tug-of-war model may fit skew data from a number of species, including meerkats, lions, and wood mice. PMID:16717185
Bissinger, George
2006-07-01
The violin bridge filter role was investigated using modal and acoustic measurements on 12 quality-rated violins combined with systematic bridge rocking frequency f(rock) and wing mass decrements deltam on four bridges for two other violins. No isolated bridge resonances were observed; bridge motions were complex (including a "squat" mode near 0.8 kHz) except for low frequency rigid body pivot motions, all more or less resembling rocking motion at higher frequencies. A conspicuous broad peak near 2.3 kHz in bridge driving point mobility (labeled BH) was seen for good and bad violins. Similar structure was seen in averaged bridge, bridge feet, corpus mobilities and averaged radiativity. No correlation between violin quality and BH driving point, averaged corpus mobility magnitude, or radiativity was found. Increasing averaged-over-f(rock) deltam(g) from 0 to 0.12 generally increased radiativity across the spectrum. Decreasing averaged-over-deltam f(rock) from 3.6 to 2.6 kHz produced consistent decreases in radiativity between 3 and 4.2 kHz, but only few-percent decreases in BH frequency. The lowest f(rock) values were accompanied by significantly reduced radiation from the Helmholtz A0 mode near 280 Hz; this, combined with reduced high frequency output, created overall radiativity profiles quite similar to "bad" violins among the quality-rated violins. PMID:16875244
Saving the Kilgore Covered Bridge.
ERIC Educational Resources Information Center
Clark, Wilma
1988-01-01
Describes an American literature class project to save a covered bridge from collapse. Illustrates how student initiative in contacting government agencies and news media, learning the history of the bridge, and raising public awareness about the project led to a joint county agreement to preserve the historic span. (DHP)
Bissinger, George
2006-07-01
The violin bridge filter role was investigated using modal and acoustic measurements on 12 quality-rated violins combined with systematic bridge rocking frequency f(rock) and wing mass decrements deltam on four bridges for two other violins. No isolated bridge resonances were observed; bridge motions were complex (including a "squat" mode near 0.8 kHz) except for low frequency rigid body pivot motions, all more or less resembling rocking motion at higher frequencies. A conspicuous broad peak near 2.3 kHz in bridge driving point mobility (labeled BH) was seen for good and bad violins. Similar structure was seen in averaged bridge, bridge feet, corpus mobilities and averaged radiativity. No correlation between violin quality and BH driving point, averaged corpus mobility magnitude, or radiativity was found. Increasing averaged-over-f(rock) deltam(g) from 0 to 0.12 generally increased radiativity across the spectrum. Decreasing averaged-over-deltam f(rock) from 3.6 to 2.6 kHz produced consistent decreases in radiativity between 3 and 4.2 kHz, but only few-percent decreases in BH frequency. The lowest f(rock) values were accompanied by significantly reduced radiation from the Helmholtz A0 mode near 280 Hz; this, combined with reduced high frequency output, created overall radiativity profiles quite similar to "bad" violins among the quality-rated violins.
Mathematics in Use: Suspension Bridges.
ERIC Educational Resources Information Center
Ginther, John L.
1992-01-01
Reviews the mathematics utilized in the design and construction of suspension bridges, in general, then illustrates these mathematical concepts by examining data associated with the Mackinac Bridge, which connects the two peninsulas of Michigan. Emphasizes the strong interest factor these gigantic structures have for students by attaching a sense…
NASA Technical Reports Server (NTRS)
Levine, Joel S.
1990-01-01
Most burning of biomass is the result of human activity, and on a global scale it is increasing. Tropospheric concentrations of CO2, CO, CH4, non-methane hydrocarbons, and ozone are all increasing with time; global biomass burning may make an important contribution to this increase and thus to potential global climate change. The nitrogen cycle also can have important climatic effects. Nitrous oxide put into the atmosphere by biomass burning is a greenhouse gas 250 times more powerful (molecule for molecule) than carbon dioxide. Nitric oxide, as well as being a photochemical precursor of ozone, a major pollutant in the troposphere, produces nitric acid, the fastest-growing component of acid rain. Hence, the new bridge in the nitrogen cycle is of more than mere technical interest.
Cascaded resonant bridge converters
NASA Technical Reports Server (NTRS)
Stuart, Thomas A. (Inventor)
1989-01-01
A converter for converting a low voltage direct current power source to a higher voltage, high frequency alternating current output for use in an electrical system where it is desired to use low weight cables and other circuit elements. The converter has a first stage series resonant (Schwarz) converter which converts the direct current power source to an alternating current by means of switching elements that are operated by a variable frequency voltage regulator, a transformer to step up the voltage of the alternating current, and a rectifier bridge to convert the alternating current to a direct current first stage output. The converter further has a second stage series resonant (Schwarz) converter which is connected in series to the first stage converter to receive its direct current output and convert it to a second stage high frequency alternating current output by means of switching elements that are operated by a fixed frequency oscillator. The voltage of the second stage output is controlled at a relatively constant value by controlling the first stage output voltage, which is accomplished by controlling the frequency of the first stage variable frequency voltage controller in response to second stage voltage. Fault tolerance in the event of a load short circuit is provided by making the operation of the first stage variable frequency voltage controller responsive to first and second stage current limiting devices. The second stage output is connected to a rectifier bridge whose output is connected to the input of the second stage to provide good regulation of output voltage wave form at low system loads.
NASA Astrophysics Data System (ADS)
Mejia-Ospino, E.; García, G.; Guerrero, A.; Alvarez, I.; Cisneros, C.
2005-01-01
The three-photon resonance four-photon ionization and dissociation spectra of dimethyl ether (DME) are presented in the wavelength range 450-550 nm at 1 nm intervals. The (3+1) REMPI spectra show three prominent bands corresponding to the \\tildeB \\leftarrow \\skew1\\tildeX, {\\skew1\\tildeC} \\leftarrow \\skew1\\tildeX and {\\skew1\\tildeC^{\\prime}} \\leftarrow \\skew1\\tildeX transitions with origins at 61 457 cm-1 (7.615 eV), 59 055 cm-1 (7.322 eV) and 58 010 cm-1 (7.194 eV), respectively. Several ionized species, CH3+, CHnO+ (n = 1-3) and CH3OCH3+, are observed in the region of wavelengths studied here. In order to compare the results, a shorter wavelength multiphoton dissociation and ionization of DME at 355 nm is also presented. At this wavelength, DME undergoes neutral dissociation to CH3 and CH3O and each fragment is then ionized by multiphoton absorption. The fragmentation at 355 nm is very intense and only small fragments such as CH3+, CHO+, CH2+, CH+ and C+ ions are observed. The measurement of photoelectron energy allows us to establish that the DME ionization potential is at least 9.55 ± 0.15 eV. The experiments were performed using a Nd:YAG-OPO (optical parametric oscillator) tunable laser system coupled to a time-of-flight mass spectrometer and a hemispherical electron energy analyser.
Verkuil, Yvonne I; Juillet, Cedric; Lank, David B; Widemo, Fredrik; Piersma, Theunis
2014-01-01
Sex differences in skews of vertebrate lifetime reproductive success are difficult to measure directly. Evolutionary histories of differential skew should be detectable in the genome. For example, male-biased skew should reduce variation in the biparentally inherited genome relative to the maternally inherited genome. We tested this approach in lek-breeding ruff (Class Aves, Philomachus pugnax) by comparing genetic variation of nuclear microsatellites (θn; biparental) versus mitochondrial D-loop sequences (θm; maternal), and conversion to comparable nuclear (Ne) and female (Nef) effective population size using published ranges of mutation rates for each marker (μ). We provide a Bayesian method to calculate Ne (θn = 4Neμn) and Nef (θm = 2Nefμm) using 95% credible intervals (CI) of θn and θm as informative priors, and accounting for uncertainty in μ. In 96 male ruffs from one population, Ne was 97% (79–100%) lower than expected under random mating in an ideal population, where Ne:Nef = 2. This substantially lower autosomal variation represents the first genomic support of strong male reproductive skew in a lekking species. PMID:25478153
ERIC Educational Resources Information Center
Cooper, David
2015-01-01
The paper looks closely at student enrolment trends through a case study of South African "race" enrolment data, including some hypotheses about how student social class has influenced these trends. First, data on 1988-1998 enrolments showing a "skewed revolution" in student africanisation are summarised. Then, using 2000-2012…
Viggiano, Emanuela; Ergoli, Manuela; Picillo, Esther; Politano, Luisa
2016-07-01
Duchenne and Becker dystrophinopathies (DMD and BMD) are X-linked recessive disorders caused by mutations in the dystrophin gene that lead to absent or reduced expression of dystrophin in both skeletal and heart muscles. DMD/BMD female carriers are usually asymptomatic, although about 8 % may exhibit muscle or cardiac symptoms. Several mechanisms leading to a reduced dystrophin have been hypothesized to explain the clinical manifestations and, in particular, the role of the skewed XCI is questioned. In this review, the mechanism of XCI and its involvement in the phenotype of BMD/DMD carriers with both a normal karyotype or with X;autosome translocations with breakpoints at Xp21 (locus of the DMD gene) will be analyzed. We have previously observed that DMD carriers with moderate/severe muscle involvement, exhibit a moderate or extremely skewed XCI, in particular if presenting with an early onset of symptoms, while DMD carriers with mild muscle involvement present a random XCI. Moreover, we found that among 87.1 % of the carriers with X;autosome translocations involving the locus Xp21 who developed signs and symptoms of dystrophinopathy such as proximal muscle weakness, difficulty to run, jump and climb stairs, 95.2 % had a skewed XCI pattern in lymphocytes. These data support the hypothesis that skewed XCI is involved in the onset of phenotype in DMD carriers, the X chromosome carrying the normal DMD gene being preferentially inactivated and leading to a moderate-severe muscle involvement. PMID:27098336
Ibbotson, Paul
2013-01-01
We use the Google Ngram database, a corpus of 5,195,769 digitized books containing ~4% of all books ever published, to test three ideas that are hypothesized to account for linguistic generalizations: verbal semantics, pre-emption and skew. Using 828,813 tokens of un-forms as a test case for these mechanisms, we found verbal semantics was a good predictor of the frequency of un-forms in the English language over the past 200 years—both in terms of how the frequency changed over time and their frequency rank. We did not find strong evidence for the direct competition of un-forms and their top pre-emptors, however the skew of the un-construction competitors was inversely correlated with the acceptability of the un-form. We suggest a cognitive explanation for this, namely, that the more the set of relevant pre-emptors is skewed then the more easily it is retrieved from memory. This suggests that it is not just the frequency of pre-emptive forms that must be taken into account when trying to explain usage patterns but their skew as well. PMID:24399991
Myers, E M; Zamudio, K R
2004-07-01
Aggregate, or explosive, breeding is widespread among vertebrates and likely increases the probability of multiple paternity. We assessed paternity in seven field-collected clutches of the explosively breeding spotted salamander (Ambystoma maculatum) using 10 microsatellite loci to determine the frequency of multiple paternity and the number of males contributing to a female's clutch. Using the Minimum Method of allele counts, multiple paternity was evident in 70% of these egg masses. Simple allele counts underestimate the number of contributing males because this method cannot distinguish multiple fathers with common or similar alleles. Therefore, we used computer simulations to estimate from the offspring genotypes the most likely number of contributing fathers given the distributions of allele frequencies in this population. We determined that two to eight males may contribute to A. maculatum clutches; therefore, multiple paternity is a common strategy in this aggregate breeding species. In aggregate mating systems competition for mates can be intense, thus differential reproductive success (reproductive skew) among males contributing to a female's clutch could be a probable outcome. We use our data to evaluate the potential effect of reproductive skew on estimates of the number of contributing males. We simulated varying scenarios of differential male reproductive success, ranging from equal contribution to high reproductive skew among contributing sires in multiply sired clutches. Our data suggest that even intermediate levels of reproductive skew decrease confidence substantially in estimates of the number of contributing sires when parental genotypes are unknown. PMID:15189216
NASA Astrophysics Data System (ADS)
Pipień, M.
2008-09-01
We present the results of an application of Bayesian inference in testing the relation between risk and return on the financial instruments. On the basis of the Intertemporal Capital Asset Pricing Model, proposed by Merton we built a general sampling distribution suitable in analysing this relationship. The most important feature of our assumptions is that the skewness of the conditional distribution of returns is used as an alternative source of relation between risk and return. This general specification relates to Skewed Generalized Autoregressive Conditionally Heteroscedastic-in-Mean model. In order to make conditional distribution of financial returns skewed we considered the unified approach based on the inverse probability integral transformation. In particular, we applied hidden truncation mechanism, inverse scale factors, order statistics concept, Beta and Bernstein distribution transformations and also a constructive method. Based on the daily excess returns on the Warsaw Stock Exchange Index we checked the empirical importance of the conditional skewness assumption on the relation between risk and return on the Warsaw Stock Market. We present posterior probabilities of all competing specifications as well as the posterior analysis of the positive sign of the tested relationship.
Sui, Yilun; Chen, Qianqian; Sun, Xiaoxi
2015-08-01
Evidence of an association between skewed X chromosome inactivation (SXCI) and idiopathic recurrent spontaneous abortion (RSA) is conflicting. No consensus has been reached on the degree of SXCI and the number of pregnancy losses in patients who have experienced RSA. In this systematic review and meta-analysis, different degrees of skewing and definitions of RSA are used to establish an association between SXCI and idiopathic RSA. Twelve studies comprising 1594 women who had experienced RSA and 1924 controls were included. No significant association was found between SXCI and RSA when 80 or 90% was used as cut-off value of skewing; more stringent 95% or greater SXCI was significantly higher in women who had experienced RSA than in controls (odds ratio [OR] = 4.27, 95% confidence interval [CI] 1.46 to 12.46). A significantly higher incidence of SXCI when defined as greater than 90% (or ≥90%) was found in women who had experienced RSA with three or more pregnancy losses (OR = 2.31, 95% CI 1.41, 3.78); significance diminished when RSA was defined as two or more losses. Extreme skewing of SXCI is associated with idiopathic RSA with three or more losses. More studies are needed to validate the potential genetic mechanism.
NASA Technical Reports Server (NTRS)
Deissler, Robert G.
1991-01-01
The variation of the velocity-derivative skewness of a Navier-Stokes flow as the Reynolds number goes toward zero is calculated numerically. The value of the skewness, which has been somewhat controversial, is shown to become small at low Reynolds numbers.
Veilleux, Andrea G.; Stedinger, Jery R.; Eash, David A.
2012-01-01
This paper summarizes methodological advances in regional log-space skewness analyses that support flood-frequency analysis with the log Pearson Type III (LP3) distribution. A Bayesian Weighted Least Squares/Generalized Least Squares (B-WLS/B-GLS) methodology that relates observed skewness coefficient estimators to basin characteristics in conjunction with diagnostic statistics represents an extension of the previously developed B-GLS methodology. B-WLS/B-GLS has been shown to be effective in two California studies. B-WLS/B-GLS uses B-WLS to generate stable estimators of model parameters and B-GLS to estimate the precision of those B-WLS regression parameters, as well as the precision of the model. The study described here employs this methodology to develop a regional skewness model for the State of Iowa. To provide cost effective peak-flow data for smaller drainage basins in Iowa, the U.S. Geological Survey operates a large network of crest stage gages (CSGs) that only record flow values above an identified recording threshold (thus producing a censored data record). CSGs are different from continuous-record gages, which record almost all flow values and have been used in previous B-GLS and B-WLS/B-GLS regional skewness studies. The complexity of analyzing a large CSG network is addressed by using the B-WLS/B-GLS framework along with the Expected Moments Algorithm (EMA). Because EMA allows for the censoring of low outliers, as well as the use of estimated interval discharges for missing, censored, and historic data, it complicates the calculations of effective record length (and effective concurrent record length) used to describe the precision of sample estimators because the peak discharges are no longer solely represented by single values. Thus new record length calculations were developed. The regional skewness analysis for the State of Iowa illustrates the value of the new B-WLS/BGLS methodology with these new extensions.
Mynard, Jonathan P; Steinman, David A
2013-05-01
Given evidence that fully developed axisymmetric flow may be the exception rather than the rule, even in nominally straight arteries, maximum velocity (V(max)) can lie outside the Doppler sample volume (SV). The link between V(max) and derived quantities, such as volume flow (Q), may therefore be more complex than commonly thought. We performed idealized virtual Doppler ultrasound on data from image-based computational fluid dynamics (CFD) models of the normal human carotid artery and investigated how velocity profile skewing and choice of sample volume affected V(max) waveforms and derived Q variables, considering common assumptions about velocity profile shape (i.e., Poiseuille or Womersley). Severe velocity profile skewing caused substantial errors in V(max) waveforms when using a small, centered SV, although peak V(max) was reliably detected; errors with a long SV covering the vessel diameter were orientation dependent but lower overall. Cycle-averaged Q calculated from V(max) was typically within ±15%, although substantial skewing and use of a small SV caused 10%-25% underestimation. Peak Q derived from Womersley's theory was generally accurate to within ±10%. V(max) pulsatility and resistance indexes differed from Q-based values, although the Q-based resistance index could be predicted reliably. Skewing introduced significant error into V(max)-derived Q waveforms, particularly during mid-to-late systole. Our findings suggest that errors in the V(max) and Q waveforms related to velocity profile skewing and use of a small SV, or orientation-dependent errors for a long SV, could limit their use in wave analysis or for constructing characteristic or patient-specific flow boundary conditions for model studies.
NPIP: A skew line needle configuration optimization system for HDR brachytherapy
Siauw, Timmy; Cunha, Adam; Berenson, Dmitry; Atamtuerk, Alper; Hsu, I-Chow; Goldberg, Ken; Pouliot, Jean
2012-07-15
Purpose: In this study, the authors introduce skew line needle configurations for high dose rate (HDR) brachytherapy and needle planning by integer program (NPIP), a computational method for generating these configurations. NPIP generates needle configurations that are specific to the anatomy of the patient, avoid critical structures near the penile bulb and other healthy structures, and avoid needle collisions inside the body. Methods: NPIP consisted of three major components: a method for generating a set of candidate needles, a needle selection component that chose a candidate needle subset to be inserted, and a dose planner for verifying that the final needle configuration could meet dose objectives. NPIP was used to compute needle configurations for prostate cancer data sets from patients previously treated at our clinic. NPIP took two user-parameters: a number of candidate needles, and needle coverage radius, {delta}. The candidate needle set consisted of 5000 needles, and a range of {delta} values was used to compute different needle configurations for each patient. Dose plans were computed for each needle configuration. The number of needles generated and dosimetry were analyzed and compared to the physician implant. Results: NPIP computed at least one needle configuration for every patient that met dose objectives, avoided healthy structures and needle collisions, and used as many or fewer needles than standard practice. These needle configurations corresponded to a narrow range of {delta} values, which could be used as default values if this system is used in practice. The average end-to-end runtime for this implementation of NPIP was 286 s, but there was a wide variation from case to case. Conclusions: The authors have shown that NPIP can automatically generate skew line needle configurations with the aforementioned properties, and that given the correct input parameters, NPIP can generate needle configurations which meet dose objectives and use as many
77 FR 16784 - General Bridge Regulation; Amendment
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-22
... SECURITY Coast Guard 33 CFR Part 114, 116, 118 RIN 1625-AB36 General Bridge Regulation; Amendment AGENCY... rulemaking concerning amendments to the general bridge regulations. The rulemaking was initiated to clarify the statutory responsibilities of bridge owners to remove their bridges from navigable waterways...
Azevedo, S
1998-10-01
The Federal Highway Administration (FHWA) has helped sponsor a research project at Lawrence Livermore that produced a beneficial new tool as well as an R&D 100 Award. The HERMES Bridge Inspector will provide an invaluable capability to diagnose the problems of deteriorating bridge decks and do it accurately, efficiently, nondestructively, and, perhaps most important to motorists, without closing bridges. Almost 30% of 600,000 large highway bridges in the U.S. are classified "deficient" by the FHWA, and HERMES can make a significant contribution toward solving the problem of infrastructure assessment and repair. With further development, HERMES holds promise for other concrete inspection problems, such as railroads, tunnels, and runways. HERMES, or High-performance Electromagnetic Roadway Mapping and Evaluation System, is a radar-based sensing system mounted in a trailer. It can be pulled by a vehicle at traffic speeds over a bridge deck to collect information about the roadway subsurface -- its sensors gathering data 30 centimeters or more into concrete. An onboard computer system processes the data into three-dimensional images that pinpoint problems in the roadway concrete and give engineers quantitative information about deterioration in the bridge deck. Engineers can then better assess what repairs or reconstruction is necessary and avoid the cost overruns and delays that result from inexact problem diagnoses.
Sacrificial bridges for MEMS fabrication
NASA Astrophysics Data System (ADS)
Chang, Chao-Min; Chen, Yang-Che; Fong, Chien-Fu; Guu, Yunn-Horng; Chen, Rongshun; Yeh, J. Andrew; Hou, Max T.
2011-09-01
This study discusses sacrificial bridges that are used to release MEMS devices. Before being released, sacrificial bridges connect all the component structures into an integral structure. Solder bump bonding is used to mount the MEMS chip on another chip or a printed circuit board (PCB) and to maintain the alignment among all component structures after removal of the sacrificial bridges. Two types of sacrificial bridges were designed, analyzed and fabricated. The fabrication process—which used low resistivity single crystal silicon (SCS) wafers as the device material—was developed to implement the sacrificial bridges. Novel SCS through silicon vias (TSVs), which interconnect stacked chips, was made using the same process. An electrostatic comb drive actuator was fabricated and mounted onto a PCB. The fabricated actuator was tested to demonstrate the feasibility of the fabrication process, sacrificial bridges and SCS TSVs. The results show that the actuator worked well. Its maximum displacement and resonant frequency were 69.9 µm and 406 Hz, respectively. This method is promising for the delivery of a novel 3D system in package for MEMS devices.
OVERVIEW OF BRIDGES WITH WAIKELE CANAL BRIDGE IN CENTER, OR&L ...
OVERVIEW OF BRIDGES WITH WAIKELE CANAL BRIDGE IN CENTER, OR&L BRIDGE IN BACKGROUND. SHOWING THE EARTHEN INCLINE THAT RAISES FARRINGTON HIGHWAY OVER THE FORMER OR&L TRACKS. NOTE THE 1963 WESTBOUND BRIDGE IN THE FOREGROUND. VIEW FACING EAST. - Waikele Canal Bridge and Highway Overpass, Farrington Highway and Waikele Stream, Waipahu, Honolulu County, HI
Viruses-to-mobile genetic elements skew in the deep Atlantis II brine pool sediments.
Adel, Mustafa; Elbehery, Ali H A; Aziz, Sherry K; Aziz, Ramy K; Grossart, Hans-Peter; Siam, Rania
2016-01-01
The central rift of the Red Sea has 25 brine pools with different physical and geochemical characteristics. Atlantis II (ATIID), Discovery Deeps (DD) and Chain Deep (CD) are characterized by high salinity, temperature and metal content. Several studies reported microbial communities in these brine pools, but few studies addressed the brine pool sediments. Therefore, sediment cores were collected from ATIID, DD, CD brine pools and an adjacent brine-influenced site. Sixteen different lithologic sediment sections were subjected to shotgun DNA pyrosequencing to generate 1.47 billion base pairs (1.47 × 10(9) bp). We generated sediment-specific reads and attempted to annotate all reads. We report the phylogenetic and biochemical uniqueness of the deepest ATIID sulfur-rich brine pool sediments. In contrary to all other sediment sections, bacteria dominate the deepest ATIID sulfur-rich brine pool sediments. This decrease in virus-to-bacteria ratio in selected sections and depth coincided with an overrepresentation of mobile genetic elements. Skewing in the composition of viruses-to-mobile genetic elements may uniquely contribute to the distinct microbial consortium in sediments in proximity to hydrothermally active vents of the Red Sea and possibly in their surroundings, through differential horizontal gene transfer. PMID:27596223
NASA Astrophysics Data System (ADS)
Hirotsuka, Isao; Tsuboi, Kazuo
The capacitor motor (CRM) is widely used to drive industrial equipments and electric home appliances. Recently, the reduction in the vibration and noise of the CRM has become increasingly important from the standpoint of environmental improvement. However, the electromagnetic vibration of the CRM under load has not been analyzed sufficiently. Therefore, we have studied the electromagnetic vibration of CRM for the purpose of reducing it. In a previous paper, the relationships for a backward magnetic field, the equivalent circuit current, and the vibration of the CRM were clarified. The present paper theoretically and experimentally discusses the effect of the slot combination and skewed slot on the electromagnetic vibration of CRM under load. The primary conclusions are as follows: (1) In the case of 4-pole and 6-pole CRMs, the dominant electromagnetic vibration of CRMs was theoretically attributed to three types of electromagnetic force waves. Two types of electromagnetic force waves are generated: one wave is generated by the interaction of two forward magnetic fluxes, such as those of a three-phase squirrel-cage induction motor, and the other wave is generated under the influence of a backward magnetic flux. (2) The characteristics of dominant electromagnetic vibration depending on load and running capacitor were classified theoretically and experimentally into three types based on the characteristics of the electromagnetic force wave and equivalent circuit current. (3) The influences of magnetic saturation in dominant electromagnetic vibration were verified experimentally and their causes were clarified theoretically in relation to electromagnetic force waves.
Gluten-containing grains skew gluten assessment in oats due to sample grind non-homogeneity.
Fritz, Ronald D; Chen, Yumin; Contreras, Veronica
2017-02-01
Oats are easily contaminated with gluten-rich kernels of wheat, rye and barley. These contaminants are like gluten 'pills', shown here to skew gluten analysis results. Using R-Biopharm R5 ELISA, we quantified gluten in gluten-free oatmeal servings from an in-market survey. For samples with a 5-20ppm reading on a first test, replicate analyses provided results ranging <5ppm to >160ppm. This suggests sample grinding may inadequately disperse gluten to allow a single accurate gluten assessment. To ascertain this, and characterize the distribution of 0.25-g gluten test results for kernel contaminated oats, twelve 50g samples of pure oats, each spiked with a wheat kernel, showed that 0.25g test results followed log-normal-like distributions. With this, we estimate probabilities of mis-assessment for a 'single measure/sample' relative to the <20ppm regulatory threshold, and derive an equation relating the probability of mis-assessment to sample average gluten content.
Skew of mantle upwelling beneath the East Pacific Rise governs segmentation.
Toomey, Douglas R; Jousselin, David; Dunn, Robert A; Wilcock, William S D; Detrick, R S
2007-03-22
Mantle upwelling is essential to the generation of new oceanic crust at mid-ocean ridges, and it is generally assumed that such upwelling is symmetric beneath active ridges. Here, however, we use seismic imaging to show that the isotropic and anisotropic structure of the mantle is rotated beneath the East Pacific Rise. The isotropic structure defines the pattern of magma delivery from the mantle to the crust. We find that the segmentation of the rise crest between transform faults correlates well with the distribution of mantle melt. The azimuth of seismic anisotropy constrains the direction of mantle flow, which is rotated nearly 10 degrees anticlockwise from the plate-spreading direction. The mismatch between the locus of mantle melt delivery and the morphologic ridge axis results in systematic differences between areas of on-axis and off-axis melt supply. We conclude that the skew of asthenospheric upwelling and transport governs segmentation of the East Pacific Rise and variations in the intensity of ridge crest processes. PMID:17377578
Application of derivative matrices of skew rays to design of compound dispersion prisms.
Lin, Psang Dain
2016-09-01
Numerous optimization methods have been developed in recent decades for optical system design. However, these methods rely heavily on ray tracing and finite difference techniques to estimate the derivative matrices of the rays. Consequently, the accuracy of the results obtained from these methods is critically dependent on the incremental step size used in the tuning stage. To overcome this limitation, the present study proposes a comprehensive methodology for the design of compound dispersion prisms based on the first- and second-order derivative matrices of skew rays. The proposed method facilitates the analysis and design of prisms with respect to arbitrary system variables and provides an ideal basis for automatic prism design applications. Four illustrative examples are given. It is shown that the optical quantities required to evaluate the prism performance can be extracted directly from the proposed derivative matrices. In addition, it is shown in this study that the single-element 3D prism can have the same deviation angle and spectral dispersion as the 2D compound prism. PMID:27607509
Dodla, Ramana; Wilson, Charles J
2013-10-01
We investigate why electrically coupled neuronal oscillators synchronize or fail to synchronize using the theory of weakly coupled oscillators. Stability of synchrony and antisynchrony is predicted analytically and verified using numerical bifurcation diagrams. The shape of the phase response curve (PRC), the shape of the voltage time course, and the frequency of spiking are freely varied to map out regions of parameter spaces that hold stable solutions. We find that type 1 and type 2 PRCs can hold both synchronous and antisynchronous solutions, but the shape of the PRC and the voltage determine the extent of their stability. This is achieved by introducing a five-piecewise linear model to the PRC and a three-piecewise linear model to the voltage time course, and then analyzing the resultant eigenvalue equations that determine the stability of the phase-locked solutions. A single time parameter defines the skewness of the PRC, and another single time parameter defines the spike width and frequency. Our approach gives a comprehensive picture of the relation of the PRC shape, voltage time course, and stability of the resultant synchronous and antisynchronous solutions.
Luo, J; Sanetra, M; Schartl, M; Meyer, A
2005-01-01
Male swordtails in the genus Xiphophorus display a conspicuous ventral elongation of the caudal fin, the sword, which arose through sexual selection due to female preference. Females mate regularly and are able to store sperm for at least 6 months. If multiple mating is frequent, this would raise the intriguing question about the role of female choice and male-male competition in shaping the mating system of these fishes. Size-dependent alternate mating strategies occur in Xiphophorus; one such strategy is courtship with a sigmoid display by large dominant males, while the other is gonopodial thrusting, in which small subordinate males sneak copulations. Using microsatellite markers, we observed a frequency of multiple paternity in wild-caught Xiphophorus multilineatus in 28% of families analyzed, but the actual frequency of multiple mating suggested by the correction factor PrDM was 33%. The number of fathers contributing genetically to the brood ranged from one to three. Compared to other species in the family Poeciliidae, both frequency and degree of multiple paternity were low. Paternity was found to be highly skewed, with one male on average contributing more than 70% to the offspring. Hence in this Xiphophorus mating system, typically one male dominates and sneaker males do not appear to be particularly effective. Postcopulatory mechanisms, however, such as sperm competition, are also indicated by our data, using sex-linked phenotypes among the offspring. PMID:15743903
Allele-Skewed DNA Modification in the Brain: Relevance to a Schizophrenia GWAS.
Gagliano, Sarah A; Ptak, Carolyn; Mak, Denise Y F; Shamsi, Mehrdad; Oh, Gabriel; Knight, Joanne; Boutros, Paul C; Petronis, Arturas
2016-05-01
Numerous recent studies have suggested that phenotypic effects of DNA sequence variants can be mediated or modulated by their epigenetic marks, such as allele-skewed DNA modification (ASM). Using Affymetrix SNP microarrays, we performed a comprehensive search of ASM effects in human post-mortem brain and sperm samples (total n = 256) from individuals with major psychosis and control individuals. Depending on the phenotypic category of the brain samples, 1.4%-7.5% of interrogated SNPs exhibited ASM effects. Next, we investigated ASM in the context of genetic studies of schizophrenia and detected that brain ASM SNPs were significantly overrepresented among sub-threshold SNPs from a schizophrenia genome-wide association study (GWAS). Brain ASM SNPs showed a much stronger enrichment in a schizophrenia GWAS than in 17 large GWASs of non-psychiatric diseases and traits, arguing that ASM effects are at least partially tissue specific. Studies of germline and control brain ASM SNPs supported a causal association between ASM and schizophrenia. Finally, significantly higher proportions of ASM SNPs than of non-ASM SNPs were detected at loci exhibiting epigenetic signatures of enhancers and promoters, and they were overrepresented within transcription factor binding regions and DNase I hypersensitive sites. All of these findings collectively indicate that ASM SNPs should be prioritized in follow-up GWASs. PMID:27087318
White, Jonah
2011-01-01
Objectives. Few studies have considered the sociohistorical intersection of environmental injustice and gentrification; a gap addressed by this case study of Seattle, Washington. This study explored the advantages of integrating air toxic risk screening with gentrification research to enhance proximity and health equity analysis methodologies. It was hypothesized that Seattle's industrial air toxic exposure risk was unevenly dispersed, that gentrification stratified the city's neighborhoods, and that the inequities of both converged. Methods. Spatial characterizations of air toxic pollution risk exposures from 1990 to 2007 were combined with longitudinal cluster analysis of census block groups in Seattle, Washington, from 1990 to 2000. Results. A cluster of air toxic exposure inequality and socioeconomic inequity converged in 1 area of south central Seattle. Minority and working class residents were more concentrated in the same neighborhoods near Seattle's worst industrial pollution risks. Conclusions. Not all pollution was distributed equally in a dynamic urban landscape. Using techniques to examine skewed riskscapes and socioeconomic urban geographies provided a foundation for future research on the connections among environmental health hazard sources, socially vulnerable neighborhoods, and health inequity. PMID:21836115
Viruses-to-mobile genetic elements skew in the deep Atlantis II brine pool sediments
NASA Astrophysics Data System (ADS)
Adel, Mustafa; Elbehery, Ali H. A.; Aziz, Sherry K.; Aziz, Ramy K.; Grossart, Hans-Peter; Siam, Rania
2016-09-01
The central rift of the Red Sea has 25 brine pools with different physical and geochemical characteristics. Atlantis II (ATIID), Discovery Deeps (DD) and Chain Deep (CD) are characterized by high salinity, temperature and metal content. Several studies reported microbial communities in these brine pools, but few studies addressed the brine pool sediments. Therefore, sediment cores were collected from ATIID, DD, CD brine pools and an adjacent brine-influenced site. Sixteen different lithologic sediment sections were subjected to shotgun DNA pyrosequencing to generate 1.47 billion base pairs (1.47 × 109 bp). We generated sediment-specific reads and attempted to annotate all reads. We report the phylogenetic and biochemical uniqueness of the deepest ATIID sulfur-rich brine pool sediments. In contrary to all other sediment sections, bacteria dominate the deepest ATIID sulfur-rich brine pool sediments. This decrease in virus-to-bacteria ratio in selected sections and depth coincided with an overrepresentation of mobile genetic elements. Skewing in the composition of viruses-to-mobile genetic elements may uniquely contribute to the distinct microbial consortium in sediments in proximity to hydrothermally active vents of the Red Sea and possibly in their surroundings, through differential horizontal gene transfer.
Gluten-containing grains skew gluten assessment in oats due to sample grind non-homogeneity.
Fritz, Ronald D; Chen, Yumin; Contreras, Veronica
2017-02-01
Oats are easily contaminated with gluten-rich kernels of wheat, rye and barley. These contaminants are like gluten 'pills', shown here to skew gluten analysis results. Using R-Biopharm R5 ELISA, we quantified gluten in gluten-free oatmeal servings from an in-market survey. For samples with a 5-20ppm reading on a first test, replicate analyses provided results ranging <5ppm to >160ppm. This suggests sample grinding may inadequately disperse gluten to allow a single accurate gluten assessment. To ascertain this, and characterize the distribution of 0.25-g gluten test results for kernel contaminated oats, twelve 50g samples of pure oats, each spiked with a wheat kernel, showed that 0.25g test results followed log-normal-like distributions. With this, we estimate probabilities of mis-assessment for a 'single measure/sample' relative to the <20ppm regulatory threshold, and derive an equation relating the probability of mis-assessment to sample average gluten content. PMID:27596406
A Timing Estimation Method Based-on Skewness Analysis in Vehicular Wireless Networks.
Cui, Xuerong; Li, Juan; Wu, Chunlei; Liu, Jian-Hang
2015-01-01
Vehicle positioning technology has drawn more and more attention in vehicular wireless networks to reduce transportation time and traffic accidents. Nowadays, global navigation satellite systems (GNSS) are widely used in land vehicle positioning, but most of them are lack precision and reliability in situations where their signals are blocked. Positioning systems base-on short range wireless communication are another effective way that can be used in vehicle positioning or vehicle ranging. IEEE 802.11p is a new real-time short range wireless communication standard for vehicles, so a new method is proposed to estimate the time delay or ranges between vehicles based on the IEEE 802.11p standard which includes three main steps: cross-correlation between the received signal and the short preamble, summing up the correlated results in groups, and finding the maximum peak using a dynamic threshold based on the skewness analysis. With the range between each vehicle or road-side infrastructure, the position of neighboring vehicles can be estimated correctly. Simulation results were presented in the International Telecommunications Union (ITU) vehicular multipath channel, which show that the proposed method provides better precision than some well-known timing estimation techniques, especially in low signal to noise ratio (SNR) environments. PMID:26580628
Kapania, R.K.; Lovejoy, A.E.
1994-12-31
Increasing use of composite materials in structures requires an accurate method of predicting response. Transverse shear effects can play an important role in laminated structures, even those that are considered thin, and as a result, should not be neglected. The free vibration response of generally laminated, thick, skewed, trapezoidal plates is investigated due of the lack of information in this area. In the method developed, Chebychev polynomials are used as displacement functions in the Rayleigh-Ritz method. To account for various edge supports, free, simply supported, and clamped, appropriate linear and rotational springs are introduced to satisfy the essential boundary conditions. First-order shear theory is used to account for transverse shear effects, and rotary inertia is also included in the model. Convergence of the solution resulting from changes in spring values and number of terms in the series is investigated. To demonstrate the accuracy of the method, results for thin isotropic and laminated plates are compared to past results for various planforms and boundary conditions. Next, thick isotropic plate results are compared to available published results. Thick laminated plate results for various planforms and boundary conditions are then presented. Variations in natural frequencies due to geometric parameter changes, such as taper ratio and sweep angle, are also studied.
A Timing Estimation Method Based-on Skewness Analysis in Vehicular Wireless Networks
Cui, Xuerong; Li, Juan; Wu, Chunlei; Liu, Jian-Hang
2015-01-01
Vehicle positioning technology has drawn more and more attention in vehicular wireless networks to reduce transportation time and traffic accidents. Nowadays, global navigation satellite systems (GNSS) are widely used in land vehicle positioning, but most of them are lack precision and reliability in situations where their signals are blocked. Positioning systems base-on short range wireless communication are another effective way that can be used in vehicle positioning or vehicle ranging. IEEE 802.11p is a new real-time short range wireless communication standard for vehicles, so a new method is proposed to estimate the time delay or ranges between vehicles based on the IEEE 802.11p standard which includes three main steps: cross-correlation between the received signal and the short preamble, summing up the correlated results in groups, and finding the maximum peak using a dynamic threshold based on the skewness analysis. With the range between each vehicle or road-side infrastructure, the position of neighboring vehicles can be estimated correctly. Simulation results were presented in the International Telecommunications Union (ITU) vehicular multipath channel, which show that the proposed method provides better precision than some well-known timing estimation techniques, especially in low signal to noise ratio (SNR) environments. PMID:26580628
Lorenzi, M C; Sella, G
2008-05-01
The role of sexual selection in shaping the mating system of hermaphrodites is currently widely accepted. However, a quantification of the intensity of sexual selection in hermaphroditic animals has never been accomplished. We evaluated the opportunity for sexual selection for both the female and the male functions in the simultaneous outcrossing hermaphrodite Ophryotrocha diadema by measuring focal hermaphrodites' paternal and maternal offspring in experimental replicated monogamous and promiscuous populations, using genetic markers to estimate paternity. Opportunity for sexual selection for each of the two sexual functions was quantified by means of the Crow's index, i.e. the ratio of variance in progeny number to the squared mean number of progeny. In addition, the extent to which the reproductive success was shared among competing individuals was estimated by means of the Nonacs's B index. We documented that the strength of selection on the male and female function in hermaphrodites with external fertilization depends on the reproductive context. Under a promiscuous regime, hermaphrodites have higher opportunities for selection for both the male and the female function than under the monogamous regime. Moreover, the reproductive skew for the female function becomes greater than that for the male function, moving from monogamy to promiscuity. In our model system, allocation to one sexual function is opposed by any degree of allocation to the other, indicating that sex-specific patterns of selection operate in this model species.
Viruses-to-mobile genetic elements skew in the deep Atlantis II brine pool sediments.
Adel, Mustafa; Elbehery, Ali H A; Aziz, Sherry K; Aziz, Ramy K; Grossart, Hans-Peter; Siam, Rania
2016-09-06
The central rift of the Red Sea has 25 brine pools with different physical and geochemical characteristics. Atlantis II (ATIID), Discovery Deeps (DD) and Chain Deep (CD) are characterized by high salinity, temperature and metal content. Several studies reported microbial communities in these brine pools, but few studies addressed the brine pool sediments. Therefore, sediment cores were collected from ATIID, DD, CD brine pools and an adjacent brine-influenced site. Sixteen different lithologic sediment sections were subjected to shotgun DNA pyrosequencing to generate 1.47 billion base pairs (1.47 × 10(9) bp). We generated sediment-specific reads and attempted to annotate all reads. We report the phylogenetic and biochemical uniqueness of the deepest ATIID sulfur-rich brine pool sediments. In contrary to all other sediment sections, bacteria dominate the deepest ATIID sulfur-rich brine pool sediments. This decrease in virus-to-bacteria ratio in selected sections and depth coincided with an overrepresentation of mobile genetic elements. Skewing in the composition of viruses-to-mobile genetic elements may uniquely contribute to the distinct microbial consortium in sediments in proximity to hydrothermally active vents of the Red Sea and possibly in their surroundings, through differential horizontal gene transfer.
NASA Technical Reports Server (NTRS)
Eberlein, A. J.; Lahm, T. G.
1976-01-01
The degree to which flight-critical failures in a strapdown laser gyro tetrad sensor assembly can be isolated in short-haul aircraft after a failure occurrence has been detected by the skewed sensor failure-detection voting logic is investigated along with the degree to which a failure in the tetrad computer can be detected and isolated at the computer level, assuming a dual-redundant computer configuration. The tetrad system was mechanized with two two-axis inertial navigation channels (INCs), each containing two gyro/accelerometer axes, computer, control circuitry, and input/output circuitry. Gyro/accelerometer data is crossfed between the two INCs to enable each computer to independently perform the navigation task. Computer calculations are synchronized between the computers so that calculated quantities are identical and may be compared. Fail-safe performance (identification of the first failure) is accomplished with a probability approaching 100 percent of the time, while fail-operational performance (identification and isolation of the first failure) is achieved 93 to 96 percent of the time.
Viruses-to-mobile genetic elements skew in the deep Atlantis II brine pool sediments
Adel, Mustafa; Elbehery, Ali H. A.; Aziz, Sherry K.; Aziz, Ramy K.; Grossart, Hans-Peter; Siam, Rania
2016-01-01
The central rift of the Red Sea has 25 brine pools with different physical and geochemical characteristics. Atlantis II (ATIID), Discovery Deeps (DD) and Chain Deep (CD) are characterized by high salinity, temperature and metal content. Several studies reported microbial communities in these brine pools, but few studies addressed the brine pool sediments. Therefore, sediment cores were collected from ATIID, DD, CD brine pools and an adjacent brine-influenced site. Sixteen different lithologic sediment sections were subjected to shotgun DNA pyrosequencing to generate 1.47 billion base pairs (1.47 × 109 bp). We generated sediment-specific reads and attempted to annotate all reads. We report the phylogenetic and biochemical uniqueness of the deepest ATIID sulfur-rich brine pool sediments. In contrary to all other sediment sections, bacteria dominate the deepest ATIID sulfur-rich brine pool sediments. This decrease in virus-to-bacteria ratio in selected sections and depth coincided with an overrepresentation of mobile genetic elements. Skewing in the composition of viruses-to-mobile genetic elements may uniquely contribute to the distinct microbial consortium in sediments in proximity to hydrothermally active vents of the Red Sea and possibly in their surroundings, through differential horizontal gene transfer. PMID:27596223
Application of derivative matrices of skew rays to design of compound dispersion prisms.
Lin, Psang Dain
2016-09-01
Numerous optimization methods have been developed in recent decades for optical system design. However, these methods rely heavily on ray tracing and finite difference techniques to estimate the derivative matrices of the rays. Consequently, the accuracy of the results obtained from these methods is critically dependent on the incremental step size used in the tuning stage. To overcome this limitation, the present study proposes a comprehensive methodology for the design of compound dispersion prisms based on the first- and second-order derivative matrices of skew rays. The proposed method facilitates the analysis and design of prisms with respect to arbitrary system variables and provides an ideal basis for automatic prism design applications. Four illustrative examples are given. It is shown that the optical quantities required to evaluate the prism performance can be extracted directly from the proposed derivative matrices. In addition, it is shown in this study that the single-element 3D prism can have the same deviation angle and spectral dispersion as the 2D compound prism.
Skew of mantle upwelling beneath the East Pacific Rise governs segmentation.
Toomey, Douglas R; Jousselin, David; Dunn, Robert A; Wilcock, William S D; Detrick, R S
2007-03-22
Mantle upwelling is essential to the generation of new oceanic crust at mid-ocean ridges, and it is generally assumed that such upwelling is symmetric beneath active ridges. Here, however, we use seismic imaging to show that the isotropic and anisotropic structure of the mantle is rotated beneath the East Pacific Rise. The isotropic structure defines the pattern of magma delivery from the mantle to the crust. We find that the segmentation of the rise crest between transform faults correlates well with the distribution of mantle melt. The azimuth of seismic anisotropy constrains the direction of mantle flow, which is rotated nearly 10 degrees anticlockwise from the plate-spreading direction. The mismatch between the locus of mantle melt delivery and the morphologic ridge axis results in systematic differences between areas of on-axis and off-axis melt supply. We conclude that the skew of asthenospheric upwelling and transport governs segmentation of the East Pacific Rise and variations in the intensity of ridge crest processes.
NASA Astrophysics Data System (ADS)
Tang, S. L.; Antonia, R. A.; Djenidi, L.; Danaila, L.; Zhou, Y.
2016-09-01
The transport equation for the mean scalar dissipation rate ɛ ¯ θ is derived by applying the limit at small separations to the generalized form of Yaglom's equation in two types of flows, those dominated mainly by a decay of energy in the streamwise direction and those which are forced, through a continuous injection of energy at large scales. In grid turbulence, the imbalance between the production of ɛ ¯ θ due to stretching of the temperature field and the destruction of ɛ ¯ θ by the thermal diffusivity is governed by the streamwise advection of ɛ ¯ θ by the mean velocity. This imbalance is intrinsically different from that in stationary forced periodic box turbulence (or SFPBT), which is virtually negligible. In essence, the different types of imbalance represent different constraints imposed by the large-scale motion on the relation between the so-called mixed velocity-temperature derivative skewness ST and the scalar enstrophy destruction coefficient Gθ in different flows, thus resulting in non-universal approaches of ST towards a constant value as Reλ increases. The data for ST collected in grid turbulence and in SFPBT indicate that the magnitude of ST is bounded, this limit being close to 0.5.
NASA Astrophysics Data System (ADS)
Hamaker, Henry Chris
1995-12-01
Statistical process control (SPC) techniques often use six times the standard deviation sigma to estimate the range of errors within a process. Two assumptions are inherent in this choice of metric for the range: (1) the normal distribution adequately describes the errors, and (2) the fraction of errors falling within plus or minus 3 sigma, about 99.73%, is sufficiently large that we may consider the fraction occurring outside this range to be negligible. In state-of-the-art photomasks, however, the assumption of normality frequently breaks down, and consequently plus or minus 3 sigma is not a good estimate of the range of errors. In this study, we show that improved estimates for the effective maximum error Em, which is defined as the value for which 99.73% of all errors fall within plus or minus Em of the mean mu, may be obtained by quantifying the deviation from normality of the error distributions using the skewness and kurtosis of the error sampling. Data are presented indicating that in laser reticle- writing tools, Em less than or equal to 3 sigma. We also extend this technique for estimating the range of errors to specifications that are usually described by mu plus 3 sigma. The implications for SPC are examined.
Development of inspection robots for bridge cables.
Yun, Hae-Bum; Kim, Se-Hoon; Wu, Liuliu; Lee, Jong-Jae
2013-01-01
This paper presents the bridge cable inspection robot developed in Korea. Two types of the cable inspection robots were developed for cable-suspension bridges and cable-stayed bridge. The design of the robot system and performance of the NDT techniques associated with the cable inspection robot are discussed. A review on recent advances in emerging robot-based inspection technologies for bridge cables and current bridge cable inspection methods is also presented.
Development of inspection robots for bridge cables.
Yun, Hae-Bum; Kim, Se-Hoon; Wu, Liuliu; Lee, Jong-Jae
2013-01-01
This paper presents the bridge cable inspection robot developed in Korea. Two types of the cable inspection robots were developed for cable-suspension bridges and cable-stayed bridge. The design of the robot system and performance of the NDT techniques associated with the cable inspection robot are discussed. A review on recent advances in emerging robot-based inspection technologies for bridge cables and current bridge cable inspection methods is also presented. PMID:24459453
Development of Inspection Robots for Bridge Cables
Kim, Se-Hoon; Lee, Jong-Jae
2013-01-01
This paper presents the bridge cable inspection robot developed in Korea. Two types of the cable inspection robots were developed for cable-suspension bridges and cable-stayed bridge. The design of the robot system and performance of the NDT techniques associated with the cable inspection robot are discussed. A review on recent advances in emerging robot-based inspection technologies for bridge cables and current bridge cable inspection methods is also presented. PMID:24459453
Ivanoff, Michael A.; Song, Donald L.
1996-01-01
The town highway 5 crossing of the Black River is a 70-ft-long, two-lane bridge consisting of one 65-foot clear span (Vermont Agency of Transportation, written commun., August 2, 1994). The bridge is supported by vertical, concrete abutments with wingwalls. There is also a retaining wall along the upstream side of the road embankments. The channel is skewed approximately 20 degrees to the opening while the opening-skew-to-roadway is 15 degrees. A scour hole 3.0 ft deeper than the mean thalweg depth was observed along the right abutment. The scour hole was 27 feet long, 15 feet wide, and was 2.5 feet below the abutment footing at the time of the Level I assessment. This right abutment had numerous cracks and had settled. Additional details describing conditions at the site are included in the Level II Summary and Appendices D and E. Scour depths and rock rip-rap sizes were computed using the general guidelines described in Hydraulic Engineering Circular 18 (Richardson and others, 1993). Scour depths were calculated assuming an infinite depth of erosive material and a homogeneous particle-size distribution. The scour analysis results are presented in tables 1 and 2 and a graph of the scour depths is presented in figure 8.
Olson, Scott A.; Ayotte, Joseph D.
1996-01-01
The town highway 5 crossing of the Black River is a 70-ft-long, two-lane bridge consisting of one 65-foot clear span (Vermont Agency of Transportation, written commun., August 2, 1994). The bridge is supported by vertical, concrete abutments with wingwalls. There is also a retaining wall along the upstream side of the road embankments. The channel is skewed approximately 20 degrees to the opening while the opening-skew-to-roadway is 15 degrees. A scour hole 3.0 ft deeper than the mean thalweg depth was observed along the right abutment. The scour hole was 27 feet long, 15 feet wide, and was 2.5 feet below the abutment footing at the time of the Level I assessment. This right abutment had numerous cracks and had settled. Additional details describing conditions at the site are included in the Level II Summary and Appendices D and E. Scour depths and rock rip-rap sizes were computed using the general guidelines described in Hydraulic Engineering Circular 18 (Richardson and others, 1993). Scour depths were calculated assuming an infinite depth of erosive material and a homogeneous particle-size distribution. The scour analysis results are presented in tables 1 and 2 and a graph of the scour depths is presented in figure 8.
Ayotte, Joseph D.
1996-01-01
The town highway 31 crossing of Lilliesville Brook is a 41-ft-long, one-lane bridge consisting of one 39-foot steel-beam span with a timber deck (Vermont Agency of Transportation, written commun., August 24, 1994). The bridge is supported by vertical, concrete abutments with wingwalls. The channel is skewed approximately 35 degrees to the opening while the opening-skew-to-roadway is 0 degrees. Scour protection measures in place at the site were type-1 stone fill (less than 12 inches diameter) at the downstream left wingwall, left abutment, and upstream and downstream sides of the left road embankment. Additional details describing conditions at the site are included in the Level II Summary and Appendices D and E. Scour depths and rock rip-rap sizes were computed using the general guidelines described in Hydraulic Engineering Circular 18 (Richardson and others, 1993). Scour depths were calculated assuming an infinite depth of erosive material and a homogeneous particle-size distribution. The scour analysis results are presented in tables 1 and 2 and a graph of the scour depths is presented in figure 8.
Dagne, Getachew; Huang, Yangxin
2012-01-01
Censored data are characteristics of many bioassays in HIV/AIDS studies where assays may not be sensitive enough to determine gradations in viral load determination among those below a detectable threshold. Not accounting for such left-censoring appropriately can lead to biased parameter estimates in most data analysis. To properly adjust for left-censoring, this paper presents an extension of the Tobit model for fitting nonlinear dynamic mixed-effects models with skew distributions. Such extensions allow one to specify the conditional distributions for viral load response to account for left-censoring, skewness and heaviness in the tails of the distributions of the response variable. A Bayesian modeling approach via Markov Chain Monte Carlo (MCMC) algorithm is used to estimate model parameters. The proposed methods are illustrated using real data from an HIV/AIDS study. PMID:22992288
Ning, S. A.; Hayman, G.; Damiani, R.; Jonkman, J.
2014-12-01
Blade element momentum methods, though conceptually simple, are highly useful for analyzing wind turbines aerodynamics and are widely used in many design and analysis applications. A new version of AeroDyn is being developed to take advantage of new robust solution methodologies, conform to a new modularization framework for National Renewable Energy Laboratory's FAST, utilize advanced skewed-wake analysis methods, fix limitations with previous implementations, and to enable modeling of highly flexible and nonstraight blades. This paper reviews blade element momentum theory and several of the options available for analyzing skewed inflow. AeroDyn implementation details are described for the benefit of users and developers. These new options are compared to solutions from the previous version of AeroDyn and to experimental data. Finally, recommendations are given on how one might select from the various available solution approaches.
Kalkan, Erol; Kwong, Neal S.
2010-01-01
The earthquake engineering profession is increasingly utilizing nonlinear response history analyses (RHA) to evaluate seismic performance of existing structures and proposed designs of new structures. One of the main ingredients of nonlinear RHA is a set of ground-motion records representing the expected hazard environment for the structure. When recorded motions do not exist (as is the case for the central United States), or when high-intensity records are needed (as is the case for San Francisco and Los Angeles), ground motions from other tectonically similar regions need to be selected and scaled. The modal-pushover-based scaling (MPS) procedure recently was developed to determine scale factors for a small number of records, such that the scaled records provide accurate and efficient estimates of 'true' median structural responses. The adjective 'accurate' refers to the discrepancy between the benchmark responses and those computed from the MPS procedure. The adjective 'efficient' refers to the record-to-record variability of responses. Herein, the accuracy and efficiency of the MPS procedure are evaluated by applying it to four types of existing 'ordinary standard' bridges typical of reinforced-concrete bridge construction in California. These bridges are the single-bent overpass, multi span bridge, curved-bridge, and skew-bridge. As compared to benchmark analyses of unscaled records using a larger catalog of ground motions, it is demonstrated that the MPS procedure provided an accurate estimate of the engineering demand parameters (EDPs) accompanied by significantly reduced record-to-record variability of the responses. Thus, the MPS procedure is a useful tool for scaling ground motions as input to nonlinear RHAs of 'ordinary standard' bridges.
Kalkan, E.; Kwong, N.
2012-01-01
The earthquake engineering profession is increasingly utilizing nonlinear response history analyses (RHA) to evaluate seismic performance of existing structures and proposed designs of new structures. One of the main ingredients of nonlinear RHA is a set of ground motion records representing the expected hazard environment for the structure. When recorded motions do not exist (as is the case in the central United States) or when high-intensity records are needed (as is the case in San Francisco and Los Angeles), ground motions from other tectonically similar regions need to be selected and scaled. The modal-pushover-based scaling (MPS) procedure was recently developed to determine scale factors for a small number of records such that the scaled records provide accurate and efficient estimates of “true” median structural responses. The adjective “accurate” refers to the discrepancy between the benchmark responses and those computed from the MPS procedure. The adjective “efficient” refers to the record-to-record variability of responses. In this paper, the accuracy and efficiency of the MPS procedure are evaluated by applying it to four types of existing Ordinary Standard bridges typical of reinforced concrete bridge construction in California. These bridges are the single-bent overpass, multi-span bridge, curved bridge, and skew bridge. As compared with benchmark analyses of unscaled records using a larger catalog of ground motions, it is demonstrated that the MPS procedure provided an accurate estimate of the engineering demand parameters (EDPs) accompanied by significantly reduced record-to-record variability of the EDPs. Thus, it is a useful tool for scaling ground motions as input to nonlinear RHAs of Ordinary Standard bridges.
26. NEW STEEL BRIDGE COMPLETED ASSEMBLED. OLD BRIDGE BELOW. U.S.G.S. ...
26. NEW STEEL BRIDGE COMPLETED ASSEMBLED. OLD BRIDGE BELOW. U.S.G.S. GAGING STATION IN RIGHT BACKGROUND. VIEW LOOKING NORTHEAST - Kaibab Trail Suspension Bridge, Spanning Colorado River, Grand Canyon, Coconino County, AZ
49 CFR 237.101 - Scheduling of bridge inspections.
Code of Federal Regulations, 2014 CFR
2014-10-01
... bridge, and the weight and frequency of traffic carried on the bridge. (c) Each bridge management program... bridge inspections. (a) Each bridge management program shall include a provision for scheduling an... for in the bridge management program when a railroad bridge engineer determines that such...
49 CFR 237.101 - Scheduling of bridge inspections.
Code of Federal Regulations, 2013 CFR
2013-10-01
... bridge, and the weight and frequency of traffic carried on the bridge. (c) Each bridge management program... bridge inspections. (a) Each bridge management program shall include a provision for scheduling an... for in the bridge management program when a railroad bridge engineer determines that such...
Fieremans, Nathalie; Bauters, Marijke; Belet, Stefanie; Verbeeck, Jelle; Jansen, Anna C; Seneca, Sara; Roelens, Filip; De Baere, Elfride; Marynen, Peter; Froyen, Guy
2014-11-01
Xq28 microduplications of MECP2 are a prominent cause of a severe syndromic form of intellectual disability (ID) in males. Females are usually unaffected through near to complete X-inactivation of the aberrant X chromosome (skewing). In rare cases, affected females have been described due to random X-inactivation. Here, we report on two female patients carrying de novo MECP2 microduplications on their fully active X chromosomes. Both patients present with ID and additional clinical features. Mono-allelic expression confirmed complete skewing of X-inactivation. Consequently, significantly enhanced MECP2 mRNA levels were observed. We hypothesize that the cause for the complete skewing is due to a more harmful mutation on the other X chromosome, thereby forcing the MECP2 duplication to become active. However, we could not unequivocally identify such a second mutation by array-CGH or exome sequencing. Our data underline that, like in males, increased MECP2 dosage in females can contribute to ID too, which should be taken into account in diagnostics.
Flow Style Investigation and Noise Reduction of a Cross-Flow Fan with Varied Rotor-Skew-Angle Rotor
NASA Astrophysics Data System (ADS)
Tsai, Go-Long; Tu, Tsung-Hsien; Li, Tung-Chen; Wang, Kuang-Hsieng
The purpose of this study was investigating the noise emission, flow-style, fan’s performance regarding to cross-fan with three different rotor-skew angle (RSA) rotors. The special flow visualization setups for both vertical and parallel investigation of smoke slice were used to overcome the blind sight of a Laser-Doppler or a particle-tracking velocimeter, and the three-dimensional flow differences were confirmed with streamline images. The experimental results indicated that RSA-5, which is a rotor with a nearly a pitch skew within blade’s two end shrouds, has a lower sound emission and little pressure drops relative to that of no skew angle case, RSA-0. RSA-10, two pitches twisting case, also has a better acoustics quietness than that of RSA-0, but it excited undesired noise in a high frequency components around 2-4kHz. In this work, for a compromise between flow and acoustics performances, RSA-5 shows the most suitable design for cross-flow fan rotor.
NASA Astrophysics Data System (ADS)
Murphy, Andrew; Aref, Thomas; Coskun, Ulas; Weinberg, Phillip; Levchenko, Alex; Vakaryuk, Victor; Bezryadin, Alexey
2013-03-01
We study statistical properties of the switching current in superconductor-graphene-superconductor proximity junctions and superconductor-nanowire-superconductor devices. The fluctuations of the switching current are related to Little's phase slips, generated by thermal and quantum fluctuations of the superconducting order parameter. The study focuses on higher moments of the statistical probability distributions of the switching current. Namely we study the skewness, which defines the asymmetry of the distribution, and kurtosis, which is a measure of the ``peakedness.'' The skewness is defined as sk= m3 /m23 / 2 where m2 is the second moment of the distribution, called the variance, and m3 is the third moment. Kurtosis is defined as kur= m4 /m22 , where m4 is the fourth moment of the distribution. It is known that for Gaussian distributions sk=0 and kur=3. On our devices we find, in most cases, sk ~ -1 and kur ~ 5. These results are in agreement with numerical simulations as well as an analytic model. Finally we present preliminary experimental results for a two-nanowire device. We have found that the standard deviation, skewness and kurtosis of the switching current distributions in these devices vary periodically with magnetic field.
Huang, Yangxin; Dagne, Getachew
2012-09-01
It is a common practice to analyze complex longitudinal data using semiparametric nonlinear mixed-effects (SNLME) models with a normal distribution. Normality assumption of model errors may unrealistically obscure important features of subject variations. To partially explain between- and within-subject variations, covariates are usually introduced in such models, but some covariates may often be measured with substantial errors. Moreover, the responses may be missing and the missingness may be nonignorable. Inferential procedures can be complicated dramatically when data with skewness, missing values, and measurement error are observed. In the literature, there has been considerable interest in accommodating either skewness, incompleteness or covariate measurement error in such models, but there has been relatively little study concerning all three features simultaneously. In this article, our objective is to address the simultaneous impact of skewness, missingness, and covariate measurement error by jointly modeling the response and covariate processes based on a flexible Bayesian SNLME model. The method is illustrated using a real AIDS data set to compare potential models with various scenarios and different distribution specifications.
47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 47 Telecommunication 5 2011-10-01 2011-10-01 false Watch required by the Bridge-to-Bridge Act. 80... Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch requirement contained in § 80.148, all vessels subject to the Bridge-to-Bridge Act must keep a watch on the...
47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 47 Telecommunication 5 2014-10-01 2014-10-01 false Watch required by the Bridge-to-Bridge Act. 80... Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch requirement contained in § 80.148, all vessels subject to the Bridge-to-Bridge Act must keep a watch on the...
47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 47 Telecommunication 5 2012-10-01 2012-10-01 false Watch required by the Bridge-to-Bridge Act. 80... Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch requirement contained in § 80.148, all vessels subject to the Bridge-to-Bridge Act must keep a watch on the...
47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 47 Telecommunication 5 2010-10-01 2010-10-01 false Watch required by the Bridge-to-Bridge Act. 80... Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch requirement contained in § 80.148, all vessels subject to the Bridge-to-Bridge Act must keep a watch on the...
47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 47 Telecommunication 5 2013-10-01 2013-10-01 false Watch required by the Bridge-to-Bridge Act. 80... Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch requirement contained in § 80.148, all vessels subject to the Bridge-to-Bridge Act must keep a watch on the...
Floating liquid bridge charge dynamics
NASA Astrophysics Data System (ADS)
Teschke, Omar; Soares, David Mendez; Gomes, Whyllerson Evaristo; Valente Filho, Juracyr Ferraz
2016-01-01
The interaction of liquid with electric fields is investigated in a configuration where up to 13 kV are applied between electrodes resulting in a 106 V/m electric field in the capillaries and where there is the formation of a free-standing fluid bridge in the interelectrode gap. The Mott-Gurney equation was fitted to the measured ionization current vs applied voltage curve which indicates that the ionization rate at the high-voltage anode electrode dimethylsulfoxide (DMSO) interface and space charging in the interelectrode gap determine the floating liquid bridge current for a given cathode-to-anode voltage. Space charge effects were measured in the cathode becker and also at the liquid bridge since the ionized charges at the anode migrate to the bridge outer surface and decrease the interfacial tension from 43 mJ/m2 to 29 mJ/m2. Two distinct structural regions then form the bridge, a charged plastic (bulk modulus ˜100 MPa) conducting outer layer with a surface conductivity of ˜10-9 Ω-1, which shapes and supports the floating fluid structure, and an inner liquid cylinder, where DMSO molecules flow.
Serotonin skews human macrophage polarization through HTR2B and HTR7.
de las Casas-Engel, Mateo; Domínguez-Soto, Angeles; Sierra-Filardi, Elena; Bragado, Rafael; Nieto, Concha; Puig-Kroger, Amaya; Samaniego, Rafael; Loza, Mabel; Corcuera, María Teresa; Gómez-Aguado, Fernando; Bustos, Matilde; Sánchez-Mateos, Paloma; Corbí, Angel L
2013-03-01
Besides its role as a neurotransmitter, serotonin (5-hydroxytryptamine, 5HT) regulates inflammation and tissue repair via a set of receptors (5HT(1-7)) whose pattern of expression varies among cell lineages. Considering the importance of macrophage polarization plasticity for inflammatory responses and tissue repair, we evaluated whether 5HT modulates human macrophage polarization. 5HT inhibited the LPS-induced release of proinflammatory cytokines without affecting IL-10 production, upregulated the expression of M2 polarization-associated genes (SERPINB2, THBS1, STAB1, COL23A1), and reduced the expression of M1-associated genes (INHBA, CCR2, MMP12, SERPINE1, CD1B, ALDH1A2). Whereas only 5HT(7) mediated the inhibitory action of 5HT on the release of proinflammatory cytokines, both 5HT(2B) and 5HT(7) receptors mediated the pro-M2 skewing effect of 5HT. In fact, blockade of both receptors during in vitro monocyte-to-macrophage differentiation preferentially modulated the acquisition of M2 polarization markers. 5HT(2B) was found to be preferentially expressed by anti-inflammatory M2(M-CSF) macrophages and was detected in vivo in liver Kupffer cells and in tumor-associated macrophages. Therefore, 5HT modulates macrophage polarization and contributes to the maintenance of an anti-inflammatory state via 5HT(2B) and 5HT(7), whose identification as functionally relevant markers for anti-inflammatory/homeostatic human M2 macrophages suggests their potential therapeutic value in inflammatory pathologies. PMID:23355731
Androgen receptor blockade using flutamide skewed sex ratio of litters in mice.
Gharagozlou, Faramarz; Youssefi, Reza; Vojgani, Mehdi; Akbarinejad, Vahid; Rafiee, Ghazaleh
2016-01-01
Maternal testosterone has been indicated to affect sex ratio of offspring. The present study was conducted to elucidate the role of androgen receptor in this regard by blockade of androgen receptor using flutamide in female mice. Mice were randomly assigned to two experimental groups. Mice in the control (n = 20) and treatment (n = 20) groups received 8 IU equine chorionic gonadotropin (eCG) followed by human chorionic gonadotropin (hCG) injection (8 IU) 47 hr later. In addition, mice in the control and treatment groups received four injections of ethanol-saline vehicle and flutamide solution (2.50 mg), respectively, started from 1 hr before eCG injection until hCG injection at 12-hr intervals. Conception rate was not different between the treatment (18/20: 90.00%) and control (19/20: 95.00%) groups (p > 0.05). Litter size was higher in the treatment (8.22 ± 0.26) than control (7.21 ± 0.28) group (p < 0.05). Male sex ratio was lower in the flutamide-treated mice (67/148: 45.30%) as compared with the untreated ones (80/137: 58.40%; odds ratio = 1.69; p < 0.05). In conclusion, the results showed that androgen receptor blockade could skew sex ratio of offspring toward females implying that the effect of testosterone on sex ratio might be through binding to androgen receptor. In addition, the blockade of androgen receptor using flutamide appeared to enhance litter size. PMID:27482363
Ji, Ting; Xu, Jing-Jing; Mace, Ruth
2014-03-01
Here we argue that models developed to examine cooperation and conflict in communal breeders, using a "tug-of-war" model of reproductive skew generated by incomplete control, are an appropriate way to model human kinship systems. We apply such models to understand the patterns of effort put into competition between father and son and between brothers in conflict over family resources in a patrilineal kinship system. Co-resident kin do not necessarily emerge with equal shares of the cake in terms of reproductive output. The models show that, depending on the efficiency with which they can gain more control of the resource, on the marriage system, and on the relatedness of the partners in conflict, individuals can do better to help their relatives breed rather than fight each other for the resources needed to reproduce. The models show that when a son's father is still breeding with his mother, sons should not compete for any share of reproduction. However, under polygyny, increased effort is spent on father/son and brother/brother conflict. Fathers will win the majority of reproduction if dominant to sons (in contrast to the finding that daughters-in-law win in conflict over mothers-in-law in patrilocal kinship systems, which has been suggested as explaining the evolution of menopause). Hence who wins in the sharing of reproduction depends not just on which sex disperses but also on the relative competitive ability of all individuals to exploit family resources. Anthropologists have long argued that cultural norms can reduce conflict. These formal evolutionary models help us to quantify the effects of reproductive conflict in families, throwing light on the evolutionary basis not just of patterns of reproductive scheduling, but also human kinship and marriage systems.
Androgen receptor blockade using flutamide skewed sex ratio of litters in mice
Gharagozlou, Faramarz; Youssefi, Reza; Vojgani, Mehdi; Akbarinejad, Vahid; Rafiee, Ghazaleh
2016-01-01
Maternal testosterone has been indicated to affect sex ratio of offspring. The present study was conducted to elucidate the role of androgen receptor in this regard by blockade of androgen receptor using flutamide in female mice. Mice were randomly assigned to two experimental groups. Mice in the control (n = 20) and treatment (n = 20) groups received 8 IU equine chorionic gonadotropin (eCG) followed by human chorionic gonadotropin (hCG) injection (8 IU) 47 hr later. In addition, mice in the control and treatment groups received four injections of ethanol-saline vehicle and flutamide solution (2.50 mg), respectively, started from 1 hr before eCG injection until hCG injection at 12-hr intervals. Conception rate was not different between the treatment (18/20: 90.00%) and control (19/20: 95.00%) groups (p > 0.05). Litter size was higher in the treatment (8.22 ± 0.26) than control (7.21 ± 0.28) group (p < 0.05). Male sex ratio was lower in the flutamide-treated mice (67/148: 45.30%) as compared with the untreated ones (80/137: 58.40%; odds ratio = 1.69; p < 0.05). In conclusion, the results showed that androgen receptor blockade could skew sex ratio of offspring toward females implying that the effect of testosterone on sex ratio might be through binding to androgen receptor. In addition, the blockade of androgen receptor using flutamide appeared to enhance litter size. PMID:27482363
Chickamauga National Military Park Tour Roads, Gordon's Slough Bridge, At ...
Chickamauga National Military Park Tour Roads, Gordon's Slough Bridge, At the confluence of Alexander's Bridge Road and Gordon's Slough, southeast of Alexander's Bridge, Fort Oglethorpe, Catoosa County, GA
27. VIEW SHOWING SOUTH ELEVATION OF NOTRE DAM BRIDGE, LOOKING ...
27. VIEW SHOWING SOUTH ELEVATION OF NOTRE DAM BRIDGE, LOOKING NORTHEAST Ernest Gould, photographer, 1987 - Notre Dame Bridge, Spanning Merrimack River on Bridge Street, Manchester, Hillsborough County, NH
2. Elkmont, deck view of corrugated arched bridge. Great ...
2. Elkmont, deck view of corrugated arched bridge. - Great Smoky Mountains National Park Roads & Bridges, Elkmont Vehicle Bridge, Spanning Little River at Elkmont Campground, Gatlinburg, Sevier County, TN
3. Elkmont, underside detail of corrugated arched bridge. Great ...
3. Elkmont, underside detail of corrugated arched bridge. - Great Smoky Mountains National Park Roads & Bridges, Elkmont Vehicle Bridge, Spanning Little River at Elkmont Campground, Gatlinburg, Sevier County, TN
Excitation Methods for Bridge Structures
Farrar, C.R.; Duffy, T.A.; Cornwell, P.J.; Doebling, S.W.
1999-02-08
This paper summarizes the various methods that have been used to excited bridge structures during dynamic testing. The excitation methods fall into the general categories of ambient excitation methods and measured-input excitation methods. During ambient excitation the input to the bridge is not directly measured. In contrast, as the category label implies, measured-input excitations are usually applied at a single location where the force input to the structure can be monitored. Issues associated with using these various types of measurements are discussed along with a general description of the various excitation methods.
Balanced bridge feedback control system
NASA Technical Reports Server (NTRS)
Lurie, Boris J. (Inventor)
1990-01-01
In a system having a driver, a motor, and a mechanical plant, a multiloop feedback control apparatus for controlling the movement and/or positioning of a mechanical plant, the control apparatus has a first local bridge feedback loop for feeding back a signal representative of a selected ratio of voltage and current at the output driver, and a second bridge feedback loop for feeding back a signal representative of a selected ratio of force and velocity at the output of the motor. The control apparatus may further include an outer loop for feeding back a signal representing the angular velocity and/or position of the mechanical plant.
Substructure Main Bridge, River Piers A & V ...
Substructure - Main Bridge, River Piers A & V - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA
During this NASA Now program, you'll meet Michael Studinger, Project Scientist for Operation IceBridge. He'll describe the purpose of the IceBridge campaign and how the campaign objectives will...
Tumors skew endothelial cells to disrupt NK cell, T-cell and macrophage functions
Mulligan, Jennifer K.; Lathers, Deanne M. R.
2012-01-01
Introduction Patients and mice with solid tumors, such as Lewis lung carcinoma (LLC), have defects in functions of immune effector cells. Endothelial cells, a component of the tumor vasculature, are potential regulators of immune cell functions. Therefore, these studies examined the impact of exposure to LLC tumor on the ability of endothelial cells to modulate immune cell functions. Materials and methods Endothelial cells were pre-treated with LLC tumor-conditioned medium (EndoT-sup) for 24 h. Control endothelial cells that were exposed to medium (EndoMedia) or epithelial cell-conditioned medium (EndoEpi-sup). After the initial 24 h incubation, endothelial cells were washed and fresh media was added. Cells were allowed to incubate for an additional 24 h. Supernatants from EndoMedia, EndoEpi-sup or EndoT-sup were collected and assayed for immune modulatory products and for immune modulatory activity. Results Supernatant from EndoT-sup contained increased levels of PGE2, IL-6 and VEGF as compared to EndoMedia and EndoEpi-sup controls. NK cell activity, as measured by TNF-α and IFN-γ secretion, was increased following exposure to media conditioned by EndoMedia and EndoEpi-sup. Exposure of NK cells to supernatants of EndoT-sup, also increases TNF-α and IFN-γ secretion, but to a lesser extent than by EndoMedia and EndoEpi-sup. Examination of macrophage functions demonstrated that supernatant from EndoT-sup decreased microbead phagocytosis and increased production of the immune suppressive mediators, IL-10 and PGE2. Lastly, T-cell responses to stimulation with anti-CD3 in the presence of supernatants from EndoT-sup were examined. IFN-γ production by CD8+ T-cells was reduced after exposure to EndoT-sup-conditioned medium, as compared to cells treatments with medium or control conditioned medium. Production of IFN-γ by CD4+ T-cells exposed to EndoT-sup was not altered. Conclusions Taken together, these studies demonstrate that tumors skew endothelial cells to
ERIC Educational Resources Information Center
Sementelli, Catherine
2001-01-01
At the Bridge School (Hillsborough, California), children with severe speech and physical disabilities are trained in the use of augmentative and alternative communication technologies, transitioned back to their home school districts, and given continuing support. Outreach and research endeavors keep the broader community informed and educated…
ERIC Educational Resources Information Center
Anderson, Richard
2008-01-01
Career and technical education (CTE) has a promising future at Darlington (WI) High School. In this article, the author describes how a class bridge project became a real-world, project-based learning opportunity involving higher-level thinking skills that are at the core of CTE at his school. It began when a local citizen approached him at the…
Bridging Cultures with Classroom Strategies.
ERIC Educational Resources Information Center
Rothstein-Fisch, Carrie; Greenfield, Patricia M.; Trumbull, Elise
1999-01-01
Collectivism, stressing family members' interdependence, is common to Latino cultures. In contrast, schools foster independence and individual achievement. To help teachers understand assumptions underlying these different values, the authors developed the "Bridging Cultures Project" as a research-based professional-development program. Science…
Over the Ramp: Building Bridges
ERIC Educational Resources Information Center
Sutton, Mary
2007-01-01
TheatreWorks is the third largest theatre in the San Francisco bay area. Through the usual educational programs that $6 million companies tend to offer, it has reached over 100,000 students of all ages in the past 8 years. The TheatreWorks Bridges Projects, however, are special. They are intricate and expansive, work with multiple community…
Instability of the capillary bridge
NASA Astrophysics Data System (ADS)
Pare, Gounseti; Hoepffner, Jerome
2014-11-01
Capillary adhesion is a physical mechanism that maintains two bodies in contact by capillarity through a liquid ligament. The capillary bridge is an idealization of this capillary adhesion. In this study we first focus on the classical case of the stability of the capillary bridge. Secondly we study a slightly more complex configuration, imagining a flow in the capillary bridge as in the case of the dynamics of the neck of a liquid ligament, in its withdrawal under the effect of capillarity. Inspired by the experiments on soap films of Plateau, the configuration analyzed consists of an initially axisymmetric, mass of fluid held by surface tension forces between two parallel, coaxial, solid pipes of the same diameter. The results presented are obtained by numerical simulations using the free software, Gerris Flow Solver. We first focus on the capillary Venturi. In the static configuration the stability diagram of the capillary bridge obtained is in perfect agreement with the results of Lev A. Slobozhanin. In the dynamic case we develop a matlab code based on the one dimensional equations of Eggers and Dupont. The comparison of the bifurcation diagram obtained and the numerical simulations shows a good agreement.
Evaluation of Summer Bridge Programs
ERIC Educational Resources Information Center
Garcia, Lisa D.; Paz, Chiara C.
2009-01-01
Many colleges and universities in the United States offer summer programs for their incoming students. While programs are structured and administered in a variety of ways and target various student populations, the most common type of summer bridge program aims to serve historically underrepresented students and students of low socioeconomic…
21. View of Clark Fork Vehicle Bridge facing west. Looking ...
21. View of Clark Fork Vehicle Bridge facing west. Looking at bridge deck, guard rail, juncture of two bridge spans. - Clark Fork Vehicle Bridge, Spanning Clark Fork River, serves Highway 200, Clark Fork, Bonner County, ID
28. Under ninth bridge, view to concrete dam and eighth ...
28. Under ninth bridge, view to concrete dam and eighth bridge in background during heavy rain, view to the SW. - Vicksburg National Military Park Roads & Bridges, Melan Arch Bridges, Spanning various tributaries at Confederate Avenue, Vicksburg, Warren County, MS
North & South Elevations and Bridge Plan Chickamauga National ...
North & South Elevations and Bridge Plan - Chickamauga National Military Park Tour Roads, Gordon's Slough Bridge, At the confluence of Alexander's Bridge Road and Gordon's Slough, southeast of Alexander's Bridge, Fort Oglethorpe, Catoosa County, GA
26. Ninth Melan Bridge on tour route, in southern area ...
26. Ninth Melan Bridge on tour route, in southern area of park, looking to the SW back to eighth bridge. - Vicksburg National Military Park Roads & Bridges, Melan Arch Bridges, Spanning various tributaries at Confederate Avenue, Vicksburg, Warren County, MS
Bridge Programs in Illinois: Results of the 2010 Illinois Bridge Status Survey
ERIC Educational Resources Information Center
Taylor, J. L.; Harmon, T.
2010-01-01
This report provides a summary of major results of the Illinois Bridge Status Survey, administered online between April and June 2010. The purpose of the survey was to understand the extent to which bridge programs are being implemented in Illinois, as well as to build an online directory of bridge programs. Bridge programs are an emerging…
77 FR 53251 - Annual Materials Report on New Bridge Construction and Bridge Rehabilitation
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-31
... Rehabilitation AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice. SUMMARY: Section 1114 of the... used in new Federal-aid bridge construction and bridge rehabilitation projects. As part of the SAFETEA... bridge construction and bridge rehabilitation projects. Data on Federal-aid and non-Federal-aid...
OVERVIEW OF BRIDGES WITH OR&L BRIDGE IN CENTER, WAIKELE CANAL ...
OVERVIEW OF BRIDGES WITH OR&L BRIDGE IN CENTER, WAIKELE CANAL BRIDGE IN BACKGROUND. SHOWING THE EARTHEN INCLINE THAT RAISES FARRINGTON HIGHWAY OVER THE FORMER OR&L TRACKS. VIEW FACING SOUTHWEST. - Waikele Canal Bridge and Highway Overpass, Farrington Highway and Waikele Stream, Waipahu, Honolulu County, HI
Structural Bridges through Fold Space
Edwards, Hannah; Deane, Charlotte M.
2015-01-01
Several protein structure classification schemes exist that partition the protein universe into structural units called folds. Yet these schemes do not discuss how these units sit relative to each other in a global structure space. In this paper we construct networks that describe such global relationships between folds in the form of structural bridges. We generate these networks using four different structural alignment methods across multiple score thresholds. The networks constructed using the different methods remain a similar distance apart regardless of the probability threshold defining a structural bridge. This suggests that at least some structural bridges are method specific and that any attempt to build a picture of structural space should not be reliant on a single structural superposition method. Despite these differences all representations agree on an organisation of fold space into five principal community structures: all-α, all-β sandwiches, all-β barrels, α/β and α + β. We project estimated fold ages onto the networks and find that not only are the pairings of unconnected folds associated with higher age differences than bridged folds, but this difference increases with the number of networks displaying an edge. We also examine different centrality measures for folds within the networks and how these relate to fold age. While these measures interpret the central core of fold space in varied ways they all identify the disposition of ancestral folds to fall within this core and that of the more recently evolved structures to provide the peripheral landscape. These findings suggest that evolutionary information is encoded along these structural bridges. Finally, we identify four highly central pivotal folds representing dominant topological features which act as key attractors within our landscapes. PMID:26372166
Structural Bridges through Fold Space.
Edwards, Hannah; Deane, Charlotte M
2015-09-01
Several protein structure classification schemes exist that partition the protein universe into structural units called folds. Yet these schemes do not discuss how these units sit relative to each other in a global structure space. In this paper we construct networks that describe such global relationships between folds in the form of structural bridges. We generate these networks using four different structural alignment methods across multiple score thresholds. The networks constructed using the different methods remain a similar distance apart regardless of the probability threshold defining a structural bridge. This suggests that at least some structural bridges are method specific and that any attempt to build a picture of structural space should not be reliant on a single structural superposition method. Despite these differences all representations agree on an organisation of fold space into five principal community structures: all-α, all-β sandwiches, all-β barrels, α/β and α + β. We project estimated fold ages onto the networks and find that not only are the pairings of unconnected folds associated with higher age differences than bridged folds, but this difference increases with the number of networks displaying an edge. We also examine different centrality measures for folds within the networks and how these relate to fold age. While these measures interpret the central core of fold space in varied ways they all identify the disposition of ancestral folds to fall within this core and that of the more recently evolved structures to provide the peripheral landscape. These findings suggest that evolutionary information is encoded along these structural bridges. Finally, we identify four highly central pivotal folds representing dominant topological features which act as key attractors within our landscapes.
49 CFR 236.713 - Bridge, movable.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Bridge, movable. 236.713 Section 236.713 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Bridge, movable. That section of a structure bridging a navigable waterway so designed that it may...
Building Bridges One Line at a Time
ERIC Educational Resources Information Center
Grigsby, Cathy Murray
2012-01-01
In this article, first-grade students were taught the different kinds of lines that were part of the construction of various bridges--the curved lines of the arches of stone bridges, straight lines connecting the cables of a suspension bridge, vertical lines, horizontal lines, and so on. They gained practice in drawing structures and in fine brush…
49 CFR 236.713 - Bridge, movable.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 4 2013-10-01 2013-10-01 false Bridge, movable. 236.713 Section 236.713 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Bridge, movable. That section of a structure bridging a navigable waterway so designed that it may...
49 CFR 236.713 - Bridge, movable.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 4 2014-10-01 2014-10-01 false Bridge, movable. 236.713 Section 236.713 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Bridge, movable. That section of a structure bridging a navigable waterway so designed that it may...
49 CFR 236.713 - Bridge, movable.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 4 2011-10-01 2011-10-01 false Bridge, movable. 236.713 Section 236.713 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Bridge, movable. That section of a structure bridging a navigable waterway so designed that it may...
49 CFR 236.713 - Bridge, movable.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 4 2012-10-01 2012-10-01 false Bridge, movable. 236.713 Section 236.713 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Bridge, movable. That section of a structure bridging a navigable waterway so designed that it may...
Remediation: Higher Education's Bridge to Nowhere
ERIC Educational Resources Information Center
Complete College America, 2012
2012-01-01
The intentions were noble. It was hoped that remediation programs would be an academic bridge from poor high school preparation to college readiness. Sadly, remediation has become instead higher education's "Bridge to Nowhere." This broken remedial bridge is travelled by some 1.7 million beginning students each year, most of whom will…
Removal of failed crown and bridge
Rahul, G R.; Poduval, Soorya T.; Shetty, Karunakar
2012-01-01
Crown and bridge have life span of many years but they fail for a number of reasons. Over the years, many devices have been designed to remove crowns and bridges from abutment teeth. While the removal of temporary crowns and bridges is usually very straightforward, the removal of a definitive cast crown with unknown cement is more challenging. Removal is often by destructive means. There are a number of circumstances, however, in which conservative disassembly would aid the practitioner in completing restorative/endodontic procedures. There are different mechanisms available to remove a failed crown or bridge. But there is no information published about the classification of available systems for crown and bridge removal. So it is logical to classify these systems into different groups which can help a clinician in choosing a particular type of system depending upon the clinical situation. The aim of this article is to provide a classification for various crown and bridge removal systems; describe how a number of systems work; and when and why they might be used. A PubMed search of English literature was conducted up to January 2010 using the terms: Crown and bridge removal, Crown and bridge disassembly, Crown and bridge failure. Additionally, the bibliographies of 3 previous reviews, their cross references as well as articles published in various journals like International Endodontic Journal, Journal of Endodontics and were manually searched. Key words:Crown and bridge removal, Crown and bridge disassembly, Crown and bridge failure. PMID:24558549
Removal of failed crown and bridge.
Sharma, Ashu; Rahul, G R; Poduval, Soorya T; Shetty, Karunakar
2012-07-01
Crown and bridge have life span of many years but they fail for a number of reasons. Over the years, many devices have been designed to remove crowns and bridges from abutment teeth. While the removal of temporary crowns and bridges is usually very straightforward, the removal of a definitive cast crown with unknown cement is more challenging. Removal is often by destructive means. There are a number of circumstances, however, in which conservative disassembly would aid the practitioner in completing restorative/endodontic procedures. There are different mechanisms available to remove a failed crown or bridge. But there is no information published about the classification of available systems for crown and bridge removal. So it is logical to classify these systems into different groups which can help a clinician in choosing a particular type of system depending upon the clinical situation. The aim of this article is to provide a classification for various crown and bridge removal systems; describe how a number of systems work; and when and why they might be used. A PubMed search of English literature was conducted up to January 2010 using the terms: Crown and bridge removal, Crown and bridge disassembly, Crown and bridge failure. Additionally, the bibliographies of 3 previous reviews, their cross references as well as articles published in various journals like International Endodontic Journal, Journal of Endodontics and were manually searched. Key words:Crown and bridge removal, Crown and bridge disassembly, Crown and bridge failure. PMID:24558549
NASA Astrophysics Data System (ADS)
Matsutani, Akihiro
2004-05-01
A comparison between the modern bridge and the baroque bridge of the violin by photoelastic observation was carried out. The relationship between the stress part and the hole is symmetric in the modern and baroque bridges. The measured spectral envelopes of baroque bridges are similar to those of modern bridges in D- or G-strings, and have peaks at a frequency higher than those of modern bridges in E-string. The visualization method as used in this study may provide hints for the design of violin bridges.
Huang, Yangxin; Yan, Chunning; Xing, Dongyuan; Zhang, Nanhua; Chen, Henian
2015-01-01
In longitudinal studies it is often of interest to investigate how a repeatedly measured marker in time is associated with a time to an event of interest. This type of research question has given rise to a rapidly developing field of biostatistics research that deals with the joint modeling of longitudinal and time-to-event data. Normality of model errors in longitudinal model is a routine assumption, but it may be unrealistically obscuring important features of subject variations. Covariates are usually introduced in the models to partially explain between- and within-subject variations, but some covariates such as CD4 cell count may be often measured with substantial errors. Moreover, the responses may encounter nonignorable missing. Statistical analysis may be complicated dramatically based on longitudinal-survival joint models where longitudinal data with skewness, missing values, and measurement errors are observed. In this article, we relax the distributional assumptions for the longitudinal models using skewed (parametric) distribution and unspecified (nonparametric) distribution placed by a Dirichlet process prior, and address the simultaneous influence of skewness, missingness, covariate measurement error, and time-to-event process by jointly modeling three components (response process with missing values, covariate process with measurement errors, and time-to-event process) linked through the random-effects that characterize the underlying individual-specific longitudinal processes in Bayesian analysis. The method is illustrated with an AIDS study by jointly modeling HIV/CD4 dynamics and time to viral rebound in comparison with potential models with various scenarios and different distributional specifications. PMID:24905593
Meeus, Sofie; Honnay, Olivier; Brys, Rein; Jacquemyn, Hans
2012-01-01
Background and Aims In heterostylous plant species, skewed morph ratios are not uncommon and may arise from a range of factors. Despite the recognized importance of skewed morph ratios on overall reproductive success within populations, little is known about the impact of skewed morph ratios on population genetic diversity and differentiation in heterostylous species. This study specifically aimed to clarify the effect of population size and morph bias on population genetic diversity and differentiation in the temperate forest herb Pulmonaria officinalis. This species is characterized by a distylous breeding system and shows morph-specific differences in reproductive success. Methods Genetic diversity was determined for 27 P. officinalis populations in northern Belgium by using eight recently developed microsatellite markers. Multiple regressions were used to assess the relationship between genetic diversity, morph bias and population size, and FST-values were calculated for short- and long-styled morphs separately to study genetic differentiation as a function of morph type. Key Results For all genetic measures used, morph bias was more important in explaining patterns of genetic diversity than population size, and in all cases patterns of population genetic diversity followed a quadratic function, which showed a symmetrical decrease in genetic diversity with increasing morph bias. However, probably due to the reproductive advantage of L-morphs relative to S-morphs, maximum genetic diversity was found in populations showing an excess of L-morphs (60·7 % L-morph). On the other hand, no significant difference in pairwise genetic distances between populations was observed between L- (0·107) and S-morphs (0·106). Conclusions Our results indicate that significant deviations from equal morph ratios not only affect plant reproductive success but also population genetic diversity of heterostylous plant species. Hence, when defining conservation measures for populations
Young, J.S.; Brain, K.L.; Cunnane, T.C.
2007-01-01
The skewed amplitude distribution of spontaneous excitatory junction potentials (sEJPs) in the mouse vas deferens and other electrically-coupled smooth muscle syncytia has been attributed to electrically-attenuated depolarizations resulting from the spontaneous release of quantized packets of ATP acting on remote smooth muscle cells (SMCs). However, in the present investigation surface SMCs of the mouse isolated vas deferens were poorly electrically coupled, with input resistances (176±18 MΩ, range: 141–221 MΩ, n=4) similar to those of dissociated cells. Furthermore, the amplitude of evoked EJPs was more variable in surface compared with deeper SMCs (F test, F=17.4, P<0.0001). Using simultaneous electrophysiology and confocal microscopy to investigate these poorly-coupled cells, it is shown that α-latrotoxin-stimulated sEJPs correlate, in timing (median delay ranged from −30 to −57 ms, P<0.05 in all experiments, n=5) and amplitude (Pearson product moment correlation, ρ>0.55 and P<0.001), with purinergic neuroeffector Ca2+ transients (NCTs) in SMCs. The temporal correlation between sEJPs of widely ranging amplitude with NCTs in the impaled SMC demonstrates that all sEJPs could arise from neurotransmitter action on the impaled cell and that the skewed distribution of sEJPs can be explained by the variable effect of packets of ATP on a single SMC. The amplitude correlation of sEJPs and NCTs argues against the attenuation of electrical signal amplitude along the length of a single SMC. The skewed sEJP amplitude distribution arising from neurotransmitter release on single SMCs is consistent with a broad neurotransmitter packet size distribution at sympathetic neuroeffector junctions. PMID:17208381
Parrett, Charles; Veilleux, Andrea; Stedinger, J.R.; Barth, N.A.; Knifong, Donna L.; Ferris, J.C.
2011-01-01
Improved flood-frequency information is important throughout California in general and in the Sacramento-San Joaquin River Basin in particular, because of an extensive network of flood-control levees and the risk of catastrophic flooding. A key first step in updating flood-frequency information is determining regional skew. A Bayesian generalized least squares (GLS) regression method was used to derive a regional-skew model based on annual peak-discharge data for 158 long-term (30 or more years of record) stations throughout most of California. The desert areas in southeastern California had too few long-term stations to reliably determine regional skew for that hydrologically distinct region; therefore, the desert areas were excluded from the regional skew analysis for California. Of the 158 long-term stations used to determine regional skew, 145 have minimally regulated annual-peak discharges, and 13 stations are dam sites for which unregulated peak discharges were estimated from unregulated daily maximum discharge data furnished by the U.S. Army Corp of Engineers. Station skew was determined by using an expected moments algorithm (EMA) program for fitting the Pearson Type 3 flood-frequency distribution to the logarithms of annual peak-discharge data. The Bayesian GLS regression method previously developed was modified because of the large cross correlations among concurrent recorded peak discharges in California and the use of censored data and historical flood information with the new expected moments algorithm. In particular, to properly account for these cross-correlation problems and develop a suitable regression model and regression diagnostics, a combination of Bayesian weighted least squares and generalized least squares regression was adopted. This new methodology identified a nonlinear function relating regional skew to mean basin elevation. The regional skew values ranged from -0.62 for a mean basin elevation of zero to 0.61 for a mean basin elevation
33 CFR 118.100 - Retroreflective panels on bridge piers.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Retroreflective panels on bridge... SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.100 Retroreflective panels on bridge piers. The... 12 inches square. (c) To mark bridge piers or channel sides on bridges not required to have...
49 CFR 237.111 - Review of bridge inspection reports.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 4 2013-10-01 2013-10-01 false Review of bridge inspection reports. 237.111... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.111 Review of bridge inspection reports. Bridge inspection reports shall be reviewed by railroad bridge supervisors and...
49 CFR 237.109 - Bridge inspection records.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 4 2013-10-01 2013-10-01 false Bridge inspection records. 237.109 Section 237.109..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.109 Bridge inspection records... performed on those bridges under this part. (b) Each record of an inspection under the bridge...
49 CFR 237.111 - Review of bridge inspection reports.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 4 2012-10-01 2012-10-01 false Review of bridge inspection reports. 237.111... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.111 Review of bridge inspection reports. Bridge inspection reports shall be reviewed by railroad bridge supervisors and...
49 CFR 237.111 - Review of bridge inspection reports.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 4 2011-10-01 2011-10-01 false Review of bridge inspection reports. 237.111... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.111 Review of bridge inspection reports. Bridge inspection reports shall be reviewed by railroad bridge supervisors and...
49 CFR 237.109 - Bridge inspection records.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Bridge inspection records. 237.109 Section 237.109..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.109 Bridge inspection records... performed on those bridges under this part. (b) Each record of an inspection under the bridge...
49 CFR 237.111 - Review of bridge inspection reports.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 4 2014-10-01 2014-10-01 false Review of bridge inspection reports. 237.111... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.111 Review of bridge inspection reports. Bridge inspection reports shall be reviewed by railroad bridge supervisors and...
33 CFR 118.100 - Retroreflective panels on bridge piers.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Retroreflective panels on bridge... SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.100 Retroreflective panels on bridge piers. The... 12 inches square. (c) To mark bridge piers or channel sides on bridges not required to have...
49 CFR 237.109 - Bridge inspection records.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 4 2012-10-01 2012-10-01 false Bridge inspection records. 237.109 Section 237.109..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.109 Bridge inspection records... performed on those bridges under this part. (b) Each record of an inspection under the bridge...
33 CFR 118.100 - Retroreflective panels on bridge piers.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Retroreflective panels on bridge... SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.100 Retroreflective panels on bridge piers. The... 12 inches square. (c) To mark bridge piers or channel sides on bridges not required to have...
33 CFR 118.100 - Retroreflective panels on bridge piers.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Retroreflective panels on bridge... SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.100 Retroreflective panels on bridge piers. The... 12 inches square. (c) To mark bridge piers or channel sides on bridges not required to have...
49 CFR 237.109 - Bridge inspection records.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 4 2014-10-01 2014-10-01 false Bridge inspection records. 237.109 Section 237.109..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.109 Bridge inspection records... performed on those bridges under this part. (b) Each record of an inspection under the bridge...
49 CFR 237.111 - Review of bridge inspection reports.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Review of bridge inspection reports. 237.111... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.111 Review of bridge inspection reports. Bridge inspection reports shall be reviewed by railroad bridge supervisors and...
49 CFR 237.109 - Bridge inspection records.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 4 2011-10-01 2011-10-01 false Bridge inspection records. 237.109 Section 237.109..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.109 Bridge inspection records... performed on those bridges under this part. (b) Each record of an inspection under the bridge...
A robust approach for skewed and heavy-tailed outcomes in the analysis of health care expenditures.
Cantoni, Eva; Ronchetti, Elvezio
2006-03-01
In this paper robust statistical procedures are presented for the analysis of skewed and heavy-tailed outcomes as they typically occur in health care data. The new estimators and test statistics are extensions of classical maximum likelihood techniques for generalized linear models. In contrast to their classical counterparts, the new robust techniques show lower variability and excellent efficiency properties in the presence of small deviations from the assumed model, i.e. when the underlying distribution of the data lies in a neighborhood of the model. A simulation study, an analysis on real data, and a sensitivity analysis confirm the good theoretical statistical properties of the new techniques.
NASA Astrophysics Data System (ADS)
Sakai, Yuji; Hukushima, Koji
2016-09-01
Recent numerical studies concerning simulated tempering algorithm without the detailed balance condition are reviewed and an irreversible simulated tempering algorithm based on the skew detailed balance condition is described. A method to estimate weight factors in simulated tempering by sequentially implementing the irreversible simulated tempering algorithm is studied in comparison with the conventional simulated tempering algorithm satisfying the detailed balance condition. It is found that the total amount of Monte Carlo steps for estimating the weight factors is successfully reduced by applying the proposed method to an two-dimensional ferromagnetic Ising model.
NASA Technical Reports Server (NTRS)
Sorenson, R. L.; Steger, J. L.
1983-01-01
An algorithm for generating computational grids about arbitrary three-dimensional bodies is developed. The elliptic partial differential equation (PDE) approach developed by Steger and Sorenson and used in the NASA computer program GRAPE is extended from two to three dimensions. Forcing functions which are found automatically by the algorithm give the user the ability to control mesh cell size and skewness at boundary surfaces. This algorithm, as is typical of PDE grid generators, gives smooth grid lines and spacing in the interior of the grid. The method is applied to a rectilinear wind-tunnel case and to two body shapes in spherical coordinates.
Diode-quad bridge circuit means
NASA Technical Reports Server (NTRS)
Harrison, D. R.; Dimeff, J. (Inventor)
1975-01-01
Diode-quad bridge circuit means is described for use as a transducer circuit or as a discriminator circuit. It includes: (1) a diode bridge having first, second, third, and fourth bridge terminals consecutively coupled together by four diodes polarized in circulating relationship; (2) a first impedance connected between the second bridge terminal and a circuit ground; (3) a second impedance connected between the fourth bridge terminal and the circuit ground; (4) a signal source having a first source terminal capacitively coupled to the first and third bridge terminals, and a second source terminal connected to the circuit ground; and (5) an output terminal coupled to the first bridge terminal and at which an output signal may be taken.
Panten, Johannes; Surburg, Horst; Hölscher, Bernd
2008-06-01
In creating new aroma molecules, the fragrance chemist can make use of several tools: receptor or combinatorial research as well as lead structure optimization of existing chemicals or substances from the natural pool. Sometimes, it is also possible to discover new structures via another way: the careful analysis of existing products and their production processes. In analyzing the production process of 1-oxacyclohexadecan-2-one (6), we identified at least two new oxa-bridged macrocyclic molecules. In continuation, these results inspired us to synthesize and evaluate more representatives with similar structures. In this contribution, presented at the RSC/SCI conference 'flavours & fragrances 2007' in London, September 24-26, 2007, the synthesis and olfactory properties of several new oxa-bridged macrocycles will be introduced and discussed.
Full-bridge capacitive extensometer
NASA Astrophysics Data System (ADS)
Peters, Randall D.
1993-08-01
Capacitive transducers have proven to be very effective sensors of small displacements, because of inherent stability and noninvasive high resolution. The most versatile ones have been those of a differential type, in which two elements are altered in opposite directions in response to change of the system parameter being monitored. Oftentimes, this differential pair has been incorporated into a bridge circuit, which is a useful means for employing synchronous detection to improve signal to noise ratios. Unlike previous differential capacitive dilatometers which used only two active capacitors, the present sensor is a full-bridge type, which is well suited to measuring low-level thermal expansions. This analog sensor is capable of 0.1 μm resolution anywhere within a range of several centimeters, with a linearity of 0.1%. Its user friendly output can be put on a strip chart recorder or directed to a computer for sophisticated data analysis.
Parabolic metamaterials and Dirac bridges
NASA Astrophysics Data System (ADS)
Colquitt, D. J.; Movchan, N. V.; Movchan, A. B.
2016-10-01
A new class of multi-scale structures, referred to as `parabolic metamaterials' is introduced and studied in this paper. For an elastic two-dimensional triangular lattice, we identify dynamic regimes, which corresponds to so-called `Dirac Bridges' on the dispersion surfaces. Such regimes lead to a highly localised and focussed unidirectional beam when the lattice is excited. We also show that the flexural rigidities of elastic ligaments are essential in establishing the `parabolic metamaterial' regimes.
NASA Technical Reports Server (NTRS)
Hannaman, David J.; Lieneweg, Udo; Buehler, Martin G.; Mantalas, Linda
1991-01-01
Integrated-circuit conductive test pattern intended to provide data on effects of design widths and design spacings upon actual widths of conductive lines. Provides for electrical measurements both on lines of unknown width and on features having known dimensions. Data from measurements on five bridges used to determine four parameters of mathematical model describing system. In principle, pattern determines effects of width and spacing and interaction between them.
Halliburton Composite Bridge Plug Assembly
Starbuck, J.M.; Luttrell, C.R.; Aramayo, G.
2005-01-15
The overall objectives of this CRADA were to assist Halliburton in analyzing a composite bridge plug and to determine why their original design was failing in the field. In Phase 1, finite element analyses were done on the original composite slip design and several alternative designs. The composite slip was the component in the bridge plug that was failing. The finite element code ABAQUS was used for these calculations and I-DEAS was used as the pre- and post-processor in the analyses. Several different designs and materials were analyzed and recommendations were made towards improving the design. In Phase 2, the objective was to develop finite element models that would accurately represent the deformations in the entire all-composite 4-1/2' diameter bridge plug assembly. The finite element code LS-DYNA was used and the results from this effort were intended to expand Halliburton's composite design and analysis capabilities with regard to developing future composite components for downhole tools. In addition to the finite element modeling, this effort involved the utilization of micromechanics to determine the necessary composite material properties that were needed as input for finite element codes.
Lamontagne, Jonathan R.; Stedinger, Jery R.; Berenbrock, Charles; Veilleux, Andrea G.; Ferris, Justin C.; Knifong, Donna L.
2012-01-01
Flood-frequency information is important in the Central Valley region of California because of the high risk of catastrophic flooding. Most traditional flood-frequency studies focus on peak flows, but for the assessment of the adequacy of reservoirs, levees, other flood control structures, sustained flood flow (flood duration) frequency data are needed. This study focuses on rainfall or rain-on-snow floods, rather than the annual maximum, because rain events produce the largest floods in the region. A key to estimating flood-duration frequency is determining the regional skew for such data. Of the 50 sites used in this study to determine regional skew, 28 sites were considered to have little to no significant regulated flows, and for the 22 sites considered significantly regulated, unregulated daily flow data were synthesized by using reservoir storage changes and diversion records. The unregulated, annual maximum rainfall flood flows for selected durations (1-day, 3-day, 7-day, 15-day, and 30-day) for all 50 sites were furnished by the U.S. Army Corps of Engineers. Station skew was determined by using the expected moments algorithm program for fitting the Pearson Type 3 flood-frequency distribution to the logarithms of annual flood-duration data. Bayesian generalized least squares regression procedures used in earlier studies were modified to address problems caused by large cross correlations among concurrent rainfall floods in California and to address the extensive censoring of low outliers at some sites, by using the new expected moments algorithm for fitting the LP3 distribution to rainfall flood-duration data. To properly account for these problems and to develop suitable regional-skew regression models and regression diagnostics, a combination of ordinary least squares, weighted least squares, and Bayesian generalized least squares regressions were adopted. This new methodology determined that a nonlinear model relating regional skew to mean basin elevation
Henry, MaLinda D.; Hankerson, Sarah J.; Siani, Jennifer M.; French, Jeffrey A.; Dietz, James M.
2013-01-01
Across taxa, cooperative breeding has been associated with high reproductive skew. Cooperatively breeding golden lion tamarins (Leontopithecus rosalia) were long thought to have a monogynous mating system in which reproduction was limited to a single dominant female. Subordinates with few reproductive opportunities delayed dispersal and remained in the natal group to provide alloparental care to siblings, thus allowing dominant reproductive females to meet the energetic needs associated with high rates of reproduction and successful infant rearing. The goal of this study was to re-assess monogyny in wild golden lion tamarin groups based upon pregnancy diagnoses that used non-invasive enzyme immunoassay for progesterone and cortisol, combined with weekly data on individual weight gain, bi-annual physical examinations noting pregnancy and lactation status and daily behavioral observations. We established quantitative and qualitative criteria to detect and determine the timing of pregnancies that did not result in the birth of infants. Pregnancy polygyny occurred in 83% of golden lion tamarin groups studied. The loss of 64% of subordinate pregnancies compared to only 15% by dominant females limited reproductive success mainly to dominant females, thus maintaining high reproductive skew in female golden lion tamarins. Pregnancy loss by subordinate adults did not appear to result from dominant interference in subordinate hormonal mechanisms, but more likely resulted from subordinate abandonment of newborn infants to mitigate dominant aggression. PMID:23454002
NASA Astrophysics Data System (ADS)
Hong, Sungryong; Calzetti, Daniela; Dickinson, Mark
2014-01-01
We present an objective method to remove the stellar continuum emission from narrow-band images to derive emission-line images. The method is based on the skewness of the pixel histogram of the residual images. Specifically, we exploit a transition in the skewness of the signal in the continuum-subtracted image, which appears when the image changes from being undersubtracted to oversubtracted. Tests on one-dimensional artificial images demonstrate that the transition identifies the optimal scaling factor μ to be used on the broad-band image IB in order to produce the optimal line-emission image IE, i.e., IE = IN-μIB, with IN the original (unsubtracted) narrow-band image. The advantage of this method is that it uses all information-bearing pixels in the final image, and not just a subset of those pixels (the latter being common in many traditional approaches to stellar continuum removal from narrow-band images). We apply our method to actual images, both from ground-based and space facilities, in particular to WFPC2 and ACS images from the Hubble Space Telescope, and we show that it is successful irrespective of the nature of the sources (point-like or extended). We also discuss the impact on the accuracy of the method of nonoptimal images, such as those containing saturated sources or nonuniform background, and present workarounds for those problems.
Chen, Jiaqing; Huang, Yangxin
2015-09-10
In longitudinal studies, it is of interest to investigate how repeatedly measured markers in time are associated with a time to an event of interest, and in the mean time, the repeated measurements are often observed with the features of a heterogeneous population, non-normality, and covariate measured with error because of longitudinal nature. Statistical analysis may complicate dramatically when one analyzes longitudinal-survival data with these features together. Recently, a mixture of skewed distributions has received increasing attention in the treatment of heterogeneous data involving asymmetric behaviors across subclasses, but there are relatively few studies accommodating heterogeneity, non-normality, and measurement error in covariate simultaneously arose in longitudinal-survival data setting. Under the umbrella of Bayesian inference, this article explores a finite mixture of semiparametric mixed-effects joint models with skewed distributions for longitudinal measures with an attempt to mediate homogeneous characteristics, adjust departures from normality, and tailor accuracy from measurement error in covariate as well as overcome shortages of confidence in specifying a time-to-event model. The Bayesian mixture of joint modeling offers an appropriate avenue to estimate not only all parameters of mixture joint models but also probabilities of class membership. Simulation studies are conducted to assess the performance of the proposed method, and a real example is analyzed to demonstrate the methodology. The results are reported by comparing potential models with various scenarios.
Ayotte, Joseph D.
1996-01-01
This report provides the results of a detailed Level II analysis of scour potential at structure NORWTH00120010 on town highway 12 crossing Bloody Brook, Norwich, Vermont (figures 1–8). A Level II study is a basic engineering analysis of the site, including a quantitative analysis of stream stability and scour (U.S. Department of Transportation, 1993). A Level I study is included in Appendix E of this report. A Level I study provides a qualitative geomorphic characterization of the study site. Information on the bridge, available from VTAOT files, was compiled prior to conducting the Level I and Level II analyses and can be found in Appendix D. The site is in the New England Upland physiographic province in east-central Vermont. The 8.98-mi2 drainage area is in a predominantly rural and forested basin. In the vicinity of the study site, the left bank upstream and the left and right banks downstream are forested. The immediate right bank upstream is covered by shrub and brush with pasture on the overbank. Town Highway 12 runs along the valley of Bloody Brook; however, at structure NORWTH00120010 the road crosses Bloody Brook at a 90-degree angle. In the study area, Bloody Brook has a sinuous channel with a slope of approximately 0.014 ft/ft, an average channel top width of 41 ft and an average channel depth of 3 ft. The predominant channel bed materials are gravel and cobble (D50 is 51.0 mm or 0.167 ft). The geomorphic assessment at the time of the Level I site visit on October 31, 1994, indicated that the reach was unstable. The town highway 12 crossing of Bloody Brook is a 34-ft-long, two-lane bridge consisting of one 30-foot clear span (Vermont Agency of Transportation, written commun., July 29, 1994). The bridge is supported by vertical, concrete abutments with wingwalls. The right abutment is protected by sparse type-2 stone fill (less than 24 inches diameter). The channel is skewed 0 degrees to the opening and the opening-skew-to-roadway is 0 degrees
Salt Bridges: Geometrically Specific, Designable Interactions
Donald, Jason E.; Kulp, Daniel W.; DeGrado, William F.
2010-01-01
Salt bridges occur frequently in proteins, providing conformational specificity and contributing to molecular recognition and catalysis. We present a comprehensive analysis of these interactions in protein structures by surveying a large database of protein structures. Salt bridges between Asp or Glu and His, Arg, or Lys display extremely well-defined geometric preferences. Several previously observed preferences are confirmed and others that were previously unrecognized are discovered. Salt bridges are explored for their preferences for different separations in sequence and in space, geometric preferences within proteins and at protein-protein interfaces, cooperativity in networked salt bridges, inclusion within metal-binding sites, preference for acidic electrons, apparent conformational side chain entropy reduction upon formation, and degree of burial. Salt bridges occur far more frequently between residues at close than distant sequence separations, but at close distances there remain strong preferences for salt bridges at specific separations. Specific types of complex salt bridges, involving three or more members, are also discovered. As we observe a strong relationship between the propensity to form a salt bridge and the placement of salt-bridging residues in protein sequences, we discuss the role that salt bridges might play in kinetically influencing protein folding and thermodynamically stabilizing the native conformation. We also develop a quantitative method to select appropriate crystal structure resolution and B-factor cutoffs. Detailed knowledge of these geometric and sequence dependences should aid de novo design and prediction algorithms. PMID:21287621
Salt bridges: geometrically specific, designable interactions.
Donald, Jason E; Kulp, Daniel W; DeGrado, William F
2011-03-01
Salt bridges occur frequently in proteins, providing conformational specificity and contributing to molecular recognition and catalysis. We present a comprehensive analysis of these interactions in protein structures by surveying a large database of protein structures. Salt bridges between Asp or Glu and His, Arg, or Lys display extremely well-defined geometric preferences. Several previously observed preferences are confirmed, and others that were previously unrecognized are discovered. Salt bridges are explored for their preferences for different separations in sequence and in space, geometric preferences within proteins and at protein-protein interfaces, co-operativity in networked salt bridges, inclusion within metal-binding sites, preference for acidic electrons, apparent conformational side chain entropy reduction on formation, and degree of burial. Salt bridges occur far more frequently between residues at close than distant sequence separations, but, at close distances, there remain strong preferences for salt bridges at specific separations. Specific types of complex salt bridges, involving three or more members, are also discovered. As we observe a strong relationship between the propensity to form a salt bridge and the placement of salt-bridging residues in protein sequences, we discuss the role that salt bridges might play in kinetically influencing protein folding and thermodynamically stabilizing the native conformation. We also develop a quantitative method to select appropriate crystal structure resolution and B-factor cutoffs. Detailed knowledge of these geometric and sequence dependences should aid de novo design and prediction algorithms.
Nondestructive evaluation techniques for enhanced bridge inspection
Thomas, G.; Benson, S.; Durbin, P.; Del Grande, N.; Haskins, J.; Brown, A.; Schneberk, D.
1993-10-01
Nondestructive evaluation of bridges is a critical aspect in the US aging infrastructure problem. For example in California there are 26,000 bridges, 3000 are made of steel, and of the steel bridges, 1000 are fracture critical. California Department of Transportation (Caltrans), Federal Highway Administration, and Lawrence Livermore National Laboratory (LLNL) are collaborating to develop and field NDE techniques to improve bridge inspections. We have demonstrated our NDE technologies on several bridge inspection applications. An early collaboration was to ultrasonically evaluate the steel pins in the E-9 pier on the San Francisco Bay Bridge. Following the Loma-Prieta earthquake in 1989 and the road way collapse at the E-9 pier, a complete nondestructive evaluation was conducted by Caltrans inspectors and several ultrasonic indications were noted. LLNL worked with Caltrans to help identify the source of these reflections. Another project was to digitally enhance high energy radiographs of bridge components such as cable end caps. We demonstrated our ability to improve the detection of corrosion and fiber breakage inside the end cap. An extension of this technology is limited view computer tomography (CT). We implemented our limited view CT software and produced cross-sectional views of bridge cables from digitized radiographic films. Most recently, we are developing dual band infrared imaging techniques to assess bridge decks for delaminations. We have demonstrated the potential of our NDE technology for enhancing the inspection of the country`s aging bridges.
Olson, Scott A.; Weber, Matthew A.
1996-01-01
bridge consisting of four concrete spans. The maximum span length is 57 ft. (Vermont Agency of Transportation, written commun., July 29, 1994). The bridge is supported by vertical, concrete abutments and three concrete piers. The toe of the left abutment is at the channel edge. The toe of the right abutment is set back on the right over-bank. The roadway centerline on the structure has a slight horizontal curve; however, the main channel is skewed approximately 5 degrees to the bridge. Additional details describing conditions at the site are included in the Level II Summary and Appendices D and E. Scour depths and rock rip-rap sizes were computed using the general guidelines described in Hydraulic Engineering Circular 18 (Richardson and others, 1993). Scour depths were calculated assuming an infinite depth of erosive material and a homogeneous particle-size distribution. The scour analysis results are presented in tables 1 and 2 and a graph of the scour depths is presented in figure 8.
Shoari, Niloofar; Dubé, Jean-Sébastien; Chenouri, Shoja'eddin
2015-11-01
In environmental studies, concentration measurements frequently fall below detection limits of measuring instruments, resulting in left-censored data. Some studies employ parametric methods such as the maximum likelihood estimator (MLE), robust regression on order statistic (rROS), and gamma regression on order statistic (GROS), while others suggest a non-parametric approach, the Kaplan-Meier method (KM). Using examples of real data from a soil characterization study in Montreal, we highlight the need for additional investigations that aim at unifying the existing literature. A number of studies have examined this issue; however, those considering data skewness and model misspecification are rare. These aspects are investigated in this paper through simulations. Among other findings, results show that for low skewed data, the performance of different statistical methods is comparable, regardless of the censoring percentage and sample size. For highly skewed data, the performance of the MLE method under lognormal and Weibull distributions is questionable; particularly, when the sample size is small or censoring percentage is high. In such conditions, MLE under gamma distribution, rROS, GROS, and KM are less sensitive to skewness. Related to model misspecification, MLE based on lognormal and Weibull distributions provides poor estimates when the true distribution of data is misspecified. However, the methods of rROS, GROS, and MLE under gamma distribution are generally robust to model misspecifications regardless of skewness, sample size, and censoring percentage. Since the characteristics of environmental data (e.g., type of distribution and skewness) are unknown a priori, we suggest using MLE based on gamma distribution, rROS and GROS.
Dynamics and Statics of Nonaxisymmetric Liquid Bridges
NASA Technical Reports Server (NTRS)
Alexander, J. Iwan D.; Resnick, Andrew H.; Slobozhanin, L. A.
1996-01-01
Theoretical and experimental investigation of the stability of nonaxisymmetric and nonaxisymmetric bridges contained between equal and unequal radii disks as a function of Bond and Weber number with emphasis on the transition from unstable axisymmetric to stable nonaxisymmetric shapes, are conducted. Numerical analysis of the stability of nonaxisymmetric bridges between unequal disks for various orientations of the gravity vector is performed. Experimental and theoretical investigation of large (nonaxisymmetric) oscillations and breaking of liquid bridges are also conducted.
Efremova, L S
2013-11-30
We use the notions of the Ω-function and functions suitable to it, to give a detailed proof of a decomposition theorem for the space of C{sup 1}-smooth skew products of interval maps whose quotient maps have complicated dynamics and satisfy the additional condition of Ω-stability with respect to the C{sup 1}-norm. In our theorem, the space of C{sup 1}-smooth skew products is decomposed into a union of four nonempty, pairwise disjoint subspaces. We give examples of maps contained in each of the four subspaces. Bibliography: 46 titles.
Quantum Bridge Fabrication Using Photolithography
Quinones, R.
2001-04-16
The need for high-speed performance electronics in computers integrated circuits and sensors, require the fabrication of low energy consumption diodes. Nano fabrication methods require new techniques and equipment. We are currently developing a procedure to fabricate a diode based on quantum-effects. The device will act like a traditional diode, but the nanometer scale will allow it to reach high speeds without over heating. This new diode will be on a nano-bridge so it can be attenuated by an electromagnetic wave. The goal is to obtain similar current vs voltage response as in a silicon diode.
Family Medicine: Bridge to Life.
Luz, Clare
2016-01-01
Reflecting on the suicide of a close friend, this essay explores what comprises, and inspires a will to live, and how those in Family Medicine can address suicide risk even in the face of debilitating or terminal illness. Research indicates that the will to live is a measurable indicator of general well-being, distinct from depression, and an important predictor of a person's motivation to "hold on to life". As such, understanding what is at the heart of a desire to live should alter clinical practice. This essay offers ideas for ways in which to create bridges for patients that could help sustain life.
HERO resistant semiconductor bridge igniter
NASA Astrophysics Data System (ADS)
Bickes, R. W., Jr.; Greenway, D.; Grubelich, M. C.; Meyer, W. J.; Hartman, J. K.; McCampbell, C. B.
1992-10-01
The problem of accidental ignition of explosive components when exposed to radio frequency (RF) environments or radiation from other electromagnetic sources is commonly referred to as Hazards of Electromagnetic Radiation to Ordnance (HERO). One illustration of such a HERO problem is the MK 149 Phalanx ammunition, which is sensitive to RF energy over a broad range of frequencies. We have demonstrated that a potential solution to the Phalanx HERO problem consists of a semiconductor bridge (SCB) igniter that incorporates microcircuitry to protect the SCB from the RF environment. Direct RF injection and ground plane tests have demonstrated the resistance of our designs to severe RF environments.
Relationship between myocardial bridging and coronary arteriosclerosis.
Sun, Jian Ling; Huang, Wei Min; Guo, Ji Hong; Li, Xiao Ying; Ma, Xian Lin; Wang, Chong Yu
2013-04-01
The objective of the study was to explore the prevalence and characteristics of myocardial bridging in patients who underwent coronary angiography and to also evaluate the correlation between bridged coronary segments and atherosclerosis. For this purpose, clinical materials of 1,500 patients who had received coronary angiography were retrospectively analyzed. The location and length of the myocardial bridge were recorded as well as the extent and location of coronary artery stenosis was described. Segments proximal and distal to the bridging were evaluated for coronary arteriosclerosis as were the remaining coronary segments. We found that myocardial bridging was present in 179 (11.9 %) patients. Bridges were frequently (84.9 %) localized in the mid-distal segment of the left anterior descending (LAD) artery. Myocardial bridging was not considered a significant risk factor for coronary atherosclerosis (odds ratio 0.58) compared with traditional cardiovascular risk factors. The incidence of coronary arteriosclerosis in the distal segments was significantly less affected than the proximal segments (P < 0.01). It was, therefore, concluded that myocardial bridging frequently localized in the mid-distal segment of the LAD artery. The presence of myocardial bridging promotes proximal atherosclerosis but it is not an additional risk factor for coronary atherosclerosis. PMID:23076634
A data management infrastructure for bridge monitoring
NASA Astrophysics Data System (ADS)
Jeong, Seongwoon; Byun, Jaewook; Kim, Daeyoung; Sohn, Hoon; Bae, In Hwan; Law, Kincho H.
2015-04-01
This paper discusses a data management infrastructure framework for bridge monitoring applications. As sensor technologies mature and become economically affordable, their deployment for bridge monitoring will continue to grow. Data management becomes a critical issue not only for storing the sensor data but also for integrating with the bridge model to support other functions, such as management, maintenance and inspection. The focus of this study is on the effective data management of bridge information and sensor data, which is crucial to structural health monitoring and life cycle management of bridge structures. We review the state-of-the-art of bridge information modeling and sensor data management, and propose a data management framework for bridge monitoring based on NoSQL database technologies that have been shown useful in handling high volume, time-series data and to flexibly deal with unstructured data schema. Specifically, Apache Cassandra and Mongo DB are deployed for the prototype implementation of the framework. This paper describes the database design for an XML-based Bridge Information Modeling (BrIM) schema, and the representation of sensor data using Sensor Model Language (SensorML). The proposed prototype data management framework is validated using data collected from the Yeongjong Bridge in Incheon, Korea.
Politicizing NIH funding: a bridge to nowhere
Epstein, Jonathan A.
2011-01-01
We live in a time of increased spending, mounting debt, and few remedies for balancing the federal budget that have bipartisan support. Unfortunately, one recent target for decreased allocations of the federal budget is the NIH; the discussion of the awarded grants and the grant funding process has been skewed and altered to present medical research in an unfriendly light, and this can have very damaging repercussions. Politicizing this process could ultimately challenge human health, technology, and economic growth. PMID:21881213
49 CFR 237.33 - Content of bridge management programs.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 4 2011-10-01 2011-10-01 false Content of bridge management programs. 237.33... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Railroad Bridge Safety Assurance § 237.33 Content of bridge management programs. Each bridge management program adopted in compliance with this...
49 CFR 237.31 - Adoption of bridge management programs.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 4 2012-10-01 2012-10-01 false Adoption of bridge management programs. 237.31... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Railroad Bridge Safety Assurance § 237.31 Adoption of bridge management programs. Each track owner shall adopt a bridge safety management program...