Sample records for small mode volume

  1. Confined Three-Dimensional Plasmon Modes inside a Ring-Shaped Nanocavity on a Silver Film Imaged by Cathodoluminescence Microscopy

    NASA Astrophysics Data System (ADS)

    Zhu, X. L.; Ma, Y.; Zhang, J. S.; Xu, J.; Wu, X. F.; Zhang, Y.; Han, X. B.; Fu, Q.; Liao, Z. M.; Chen, L.; Yu, D. P.

    2010-09-01

    The confined modes of surface plasmon polaritons in boxing ring-shaped nanocavities have been investigated and imaged by using cathodoluminescence spectroscopy. The mode of the out-of-plane field components of surface plasmon polaritons dominates the experimental mode patterns, indicating that the electron beam locally excites the out-of-plane field component of surface plasmon polaritons. Quality factors can be directly acquired from the spectra induced by the ultrasmooth surface of the cavity and the high reflectivity of the silver (Ag) reflectors. Because of its three-dimensional confined characteristics and the omnidirectional reflectors, the nanocavity exhibits a small modal volume, small total volume, rich resonant modes, and flexibility in mode control.

  2. Analysis of Dual Mode Systems in an Urban Area : Volume 2. Study Results.

    DOT National Transportation Integrated Search

    1973-12-01

    Various forms of Dual Mode transportation were analyzed in order to assess the economic viability of the dual mode concept. Specially designed new small Dual Mode vehicles, modifications of existing automobiles, and pallet systems, all operating in c...

  3. Analysis of Dual Mode Systems in an Urban Area : Volume 1. Summary.

    DOT National Transportation Integrated Search

    1973-12-01

    Various forms of Dual Mode transportation were analyzed in order to assess the economic viability of the dual mode concept. Specially designed new small Dual Mode vehicles, modifications of existing automobiles, and pallet systems, all operating in c...

  4. Confined Three-Dimensional Plasmon Modes inside a Ring-Shaped Nanocavity on a Silver Film Imaged by Cathodoluminescence Microscopy

    NASA Astrophysics Data System (ADS)

    Zhu, Xinli; Zhang, Jiasen; Xu, Jun; Yu, Dapeng

    2011-03-01

    The confined modes of surface plasmon polaritons in boxing ring-shaped nanocavities have been investigated and imaged by using cathodoluminescence spectroscopy. The mode of the out-of-plane field components of surface plasmon polaritons dominates the experimental mode patterns, indicating that the electron beam locally excites the out-of-plane field component of surface plasmon polaritons. Quality factors can be directly acquired from the spectra induced by the ultrasmooth surface of the cavity and the high reflectivity of the silver reflectors. Because of its three-dimensional confined characteristics and the omnidirectional reflectors, the nanocavity exhibits a small modal volume, small total volume, rich resonant modes, and flexibility in mode control. This work is supported by NSFC (10804003, 61036005 and 11074015), the national 973 program of China (2007CB936203, 2009CB623703), MOST and NSFC/RGC (N HKUST615/06).

  5. Analysis of Dual Mode Systems in an Urban Area : Volume 3. Description of the Analysis Techniques and Data Sources.

    DOT National Transportation Integrated Search

    1973-12-01

    Various forms of Dual Mode transportation were analyzed in order to assess the economic viability of the dual mode concept. Specially designed new small Dual Mode vehicles, modifications of existing automobiles, and pallet systems, all operating in c...

  6. Analysis of Dual Mode Systems in an Urban Area : Volume 3. Description of the Analysis Techniques and Data Sources

    DOT National Transportation Integrated Search

    1973-12-01

    Various forms of Dual Mode transportation were analyzed in order to assess the economic viability of the dual mode concept. Specially designed new small Dual Mode vehicles, modifications of existing automobiles, and pallet systems, all operating in c...

  7. A small mode volume tunable microcavity: Development and characterization

    NASA Astrophysics Data System (ADS)

    Greuter, Lukas; Starosielec, Sebastian; Najer, Daniel; Ludwig, Arne; Duempelmann, Luc; Rohner, Dominik; Warburton, Richard J.

    2014-09-01

    We report the realization of a spatially and spectrally tunable air-gap Fabry-Pérot type microcavity of high finesse and cubic-wavelength-scale mode volume. These properties are attractive in the fields of opto-mechanics, quantum sensing, and foremost cavity quantum electrodynamics. The major design feature is a miniaturized concave mirror with atomically smooth surface and radius of curvature as low as 10 μm produced by CO2 laser ablation of fused silica. We demonstrate excellent mode-matching of a focussed laser beam to the microcavity mode and confirm from the frequencies of the resonator modes that the effective optical radius matches the physical radius. With these small radii, we demonstrate wavelength-size beam waists. We also show that the microcavity is sufficiently rigid for practical applications: in a cryostat at 4 K, the root-mean-square microcavity length fluctuations are below 5 pm.

  8. Burst mode pumping: A new mechanism of drinking in mosquitoes

    DOE PAGES

    Kikuchi, Kenji; Stremler, Mark A.; Chatterjee, Souvick; ...

    2018-03-20

    Mosquitoes transport liquid foods into the body using two muscular pumps in the head. In normal drinking, these pumps reciprocate in a stereotyped pattern of oscillation, with a high frequency but small stroke volume. Do mosquitoes modulate their neuromotor programs for pumping to produce different drinking modes? More broadly, what are the mechanical consequences of a two-pump system in insects? To address these questions, we used synchrotron x-ray imaging and fluid mechanical modeling to investigate drinking performance in mosquitoes. X-ray imaging of the pumps during drinking revealed two modes of pumping: continuous reciprocation with multiple small strokes, and a newlymore » discovered ‘burst mode’ involving a single, large-volume stroke. Results from modeling demonstrate that burst mode pumping creates a very large pressure drop and high volume flow rate, but requires a massive increase in power, suggesting that continuous pumping is more economical for drinking. Modeling also demonstrates that, from one mode of pumping to the other, the mechanical role of the individual pumps changes. Furthermore, these results suggest that the advantage of a two-pump system in insects lies in its flexibility, enabling the animal to pump efficiently or powerfully as demanded by environmental considerations.« less

  9. Burst mode pumping: A new mechanism of drinking in mosquitoes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kikuchi, Kenji; Stremler, Mark A.; Chatterjee, Souvick

    Mosquitoes transport liquid foods into the body using two muscular pumps in the head. In normal drinking, these pumps reciprocate in a stereotyped pattern of oscillation, with a high frequency but small stroke volume. Do mosquitoes modulate their neuromotor programs for pumping to produce different drinking modes? More broadly, what are the mechanical consequences of a two-pump system in insects? To address these questions, we used synchrotron x-ray imaging and fluid mechanical modeling to investigate drinking performance in mosquitoes. X-ray imaging of the pumps during drinking revealed two modes of pumping: continuous reciprocation with multiple small strokes, and a newlymore » discovered ‘burst mode’ involving a single, large-volume stroke. Results from modeling demonstrate that burst mode pumping creates a very large pressure drop and high volume flow rate, but requires a massive increase in power, suggesting that continuous pumping is more economical for drinking. Modeling also demonstrates that, from one mode of pumping to the other, the mechanical role of the individual pumps changes. Furthermore, these results suggest that the advantage of a two-pump system in insects lies in its flexibility, enabling the animal to pump efficiently or powerfully as demanded by environmental considerations.« less

  10. COMPARISON OF THORACIC ULTRASONOGRAPHY AND RADIOGRAPHY FOR THE DETECTION OF INDUCED SMALL VOLUME PNEUMOTHORAX IN THE HORSE.

    PubMed

    Partlow, Jessica; David, Florent; Hunt, Luanne Michelle; Relave, Fabien; Blond, Laurent; Pinilla, Manuel; Lavoie, Jean-Pierre

    2017-05-01

    Small volume pneumothorax can be challenging to diagnose in horses. The current standard method for diagnosis is standing thoracic radiography. We hypothesized that thoracic ultrasonography would be more sensitive. Objectives of this prospective, experimental study were to describe a thoracic ultrasound method for detection of small volume pneumothorax in horses and to compare results of radiography and ultrasound in a sample of horses with induced small volume pneumothorax. Six mature healthy horses were recruited for this study. For each horse, five 50 ml air boluses were sequentially introduced via a teat cannula into the pleural space. Lateral thoracic radiographs and standardized ultrasound (2D and M-mode) examinations of both hemithoraces were performed following administration of each 50 ml air bolus. Radiographs and ultrasound images/videos were analyzed for detection of pneumothorax by four independent investigators who were unaware of treatment status. Sensitivity, specificity, positive predictive values, negative predictive values, and agreement among investigators (Kappa test, κ) were calculated for radiography, 2D and M-mode ultrasound. Comparisons were made using a chi-squared exact test with significance set at P < 0.05. Two-dimensional (84%) and M-mode (80%) ultrasound were more sensitive than radiography (48%) for pneumothorax detection (P = 0.02 and P = 0.04, respectively). Specificity and positive predictive values were similar for all three imaging modalities (P = 1). Agreement between investigators for pneumothorax detection was excellent for 2D ultrasound (κ = 1), very good for M-mode ultrasound (κ = 0.87), and good for radiography (κ = 0.79). Findings from this experimental study supported the use of thoracic ultrasonography as a diagnostic method for detecting pneumothorax in horses. © 2017 American College of Veterinary Radiology.

  11. Heaving buoys, point absorbers and arrays.

    PubMed

    Falnes, Johannes; Hals, Jørgen

    2012-01-28

    Absorption of wave energy may be considered as a phenomenon of interference between incident and radiated waves generated by an oscillating object; a wave-energy converter (WEC) that displaces water. If a WEC is very small in comparison with one wavelength, it is classified as a point absorber (PA); otherwise, as a 'quasi-point absorber'. The latter may be a dipole-mode radiator, for instance an immersed body oscillating in the surge mode or pitch mode, while a PA is so small that it should preferably be a source-mode radiator, for instance a heaving semi-submerged buoy. The power take-off capacity, the WEC's maximum swept volume and preferably also its full physical volume should be reasonably matched to the wave climate. To discuss this matter, two different upper bounds for absorbed power are applied in a 'Budal diagram'. It appears that, for a single WEC unit, a power capacity of only about 0.3 MW matches well to a typical offshore wave climate, and the full physical volume has, unfortunately, to be significantly larger than the swept volume, unless phase control is used. An example of a phase-controlled PA is presented. For a sizeable wave-power plant, an array consisting of hundreds, or even thousands, of mass-produced WEC units is required.

  12. PC-403: Pioneer Venus multiprobe spacecraft mission operational characteristics document, volume 3

    NASA Technical Reports Server (NTRS)

    Barker, F. C.

    1978-01-01

    The Pioneer Venus spacecraft primary and backup operational modes and operational limitations for maneuvers, roll references transfer, attitude determination, spacecraft power discipline and spacecraft thermal discipline, are described. The functions and operations of the large and small probes, as well detailed performance in the normal operating modes and backup modes are presented.

  13. Rheology of Foam Near the Order-Disorder Transition

    NASA Technical Reports Server (NTRS)

    Holt, R. Glynn; McDaniel, J. Gregory

    2001-01-01

    The first part of our research results are summarized in the recent journal publication: J. Gregory McDaniel and R. Glynn Holt, 'Measurement of aqueous foam rheology by acoustic levitation', Phys. Rev. E 61, 2204 (2000). This aspect of the work was a combination of experiment and analysis. We built a levitation system capable of acoustically levitating small samples of aqueous foam of arbitrary gas and liquid volume fractions. We then modulated the acoustic field to induce normal mode oscillations of the foam samples. The observables from the experiment were frequency and mode number. For dry (roughly > 70% gas by volume) foams and small deformations, we developed an effective medium, normal-modes analysis which took the frequency and mode number from experiment, and gave us the shear elastic modulus of the foam as a function of Poisson's ratio. The second part of our results may be found in a soon-to-be submitted manuscript 'Dynamics of aqueous foam drops', I.Sh. Akhatov, J.G. McDaniel and R.G. Holt, describing our modeling in the wet foam limit by considering the acoustic problem. This aspect of the research is purely theoretical. Beginning from a mass-conserving mixture law, the fully nonlinear equations of motion for a wet (roughly < 10% gas by volume) foam drop of initially spherical shape were derived. The frequencies for normal mode oscillations were derived in the linear inviscid limit. The nonlinear equations were numerically solved to elicit the motion of a foam drop under acoustic excitation. The role of the time-varying void fraction in breathing-mode oscillations is of particular interest. As of the end of the current (NAG#3-2121) grant, this work was not yet concluded. We continue to work on this aspect in order to extend the analysis to cover the transition regime of gas volume fractions, as well as to compare to experiments in the wet regime.

  14. Small ICBM area narrowing report. Volume 3: Hard silo in patterned array basing mode

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The purpose of this report is to identify those areas that could potentially support deployment of the Small Intercontinental Ballistic Missile (ICBM) utilizing basing modes presently considered viable: the Hard Mobile Launcher in Random Movement, the Hard Mobile Launcher at Minuteman Facilities, or the Hard Silo in Patterned Array. Specifically, this report describes the process and the rationale supporting the application of Exclusionary and Evaluative Criteria and lists those locations that were eliminated through the application of these criteria. The remaining locations will be the subject of further investigations.

  15. Constant pressure mode extended simple gradient liquid chromatography system for micro and nanocolumns.

    PubMed

    Šesták, Jozef; Kahle, Vladislav

    2014-07-11

    Performing gradient liquid chromatography at constant pressure instead of constant flow rate has serious potential for shortening the analysis time and increasing the productivity of HPLC instruments that use gradient methods. However, in the constant pressure mode the decreasing column permeability during a long period of time negatively affects the repeatability of retention time. Thus a volume-based approach, in which the detector signal is plotted as a function of retention volume, must be taken into consideration. Traditional HPLC equipment, however, requires quite complex hardware and software modifications in order to work at constant pressure and in the volume-based mode. In this short communication, a low cost and easily feasible pressure-controlled extension of the previously described simple gradient liquid chromatography platform is proposed. A test mixture of four nitro esters was separated by 10-60% (v/v) acetone/water gradient and a high repeatability of retention volumes at 20MPa (RSD less than 0.45%) was realized. Separations were also performed at different values of pressure (20, 25, and 31MPa), and only small variations of the retention volumes (up to 0.8%) were observed. In this particular case, the gain in the analysis speed of 7% compared to the constant flow mode was realized at a constant pressure. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Small ICBM area narrowing report. Volume 1. Hard mobile launcher in random movement basing mode

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The purpose of this report is to identify those areas that could potentially support deployment of the Small Intercontinental Ballistic Missile (ICBM) utilizing basing modes presently considered viable: the Hard Mobile Launcher in Random Movement, the Hard Mobile Launcher at Minuteman Facilities, and the Hard Silo in Patterned Array. Specifically, this report describes the process and the rationale supporting the application of Exclusionary and Evaluative Criteria and lists those locations that were eliminated through the application of these criteria. The remaining locations will be the subject of further investigations.

  17. Small ICBM area narrowing report. Volume 2. Hard mobile launcher at minuteman facilities basing mode

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The purpose of this report is to identify those areas that could potentially support deployment of the Small Intercontinental Ballistic Missile (ICBM) utilizing basing modes presently considered viable: the Hard Mobile Launcher in Random Movement, the Hard Mobile Launcher at Minuteman Facilities, and the Hard Silo in Patterned Array. Specifically, this report describes the process and the rationale supporting the application of Exclusionary and Evaluative Criteria and lists those locations that were eliminated through the application of these criteria. The remaining locations will be the subject of further investigations.

  18. Photoacoustics of disperse systems: Below cavitation threshold

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Egerev, Sergey; Ovchinnikov, Oleg

    2012-05-24

    The paper considers photoacoustic (PA) conversion while irradiating suspensions in extra-small volume probes with laser pulses having small fluence values. Only linear and nonlinear thermooptical laser sound generation regimes were observed. Thus, good repeatability of acoustic signal parameters informative about probe content was achieved. The experiment conducted has shown how one can avoid the decrease of particles detection sensitivity for the thermooptical mode.

  19. Component mode synthesis and large deflection vibration of complex structures. Volume 1: Examples of NASTRAN modal synthesis capability

    NASA Technical Reports Server (NTRS)

    Mei, Chuh; Shen, Mo-How

    1987-01-01

    The use of NASTRAN model synthesis capability is illustrated. A classical truss problem is examined and the results are compared to results from other methods to test for accuracy. The problem is examined using both fixed interface modes and free interface modes. The solution is carried out for an applied dynamic load as far as recovery of forces in individual members as a function of time. Another small beam problem is used to compare different means of combining substructures.

  20. Implementing the DC Mode in Cosmological Simulations with Supercomoving Variables

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gnedin, Nickolay Y; Kravtsov, Andrey V; Rudd, Douglas H

    2011-06-02

    As emphasized by previous studies, proper treatment of the density fluctuation on the fundamental scale of a cosmological simulation volume - the 'DC mode' - is critical for accurate modeling of spatial correlations on scales ~> 10% of simulation box size. We provide further illustration of the effects of the DC mode on the abundance of halos in small boxes and show that it is straightforward to incorporate this mode in cosmological codes that use the 'supercomoving' variables. The equations governing evolution of dark matter and baryons recast with these variables are particularly simple and include the expansion factor, andmore » hence the effect of the DC mode, explicitly only in the Poisson equation.« less

  1. Defense Small Business Innovation Research Program (SBIR). Volume 2. Navy Abstracts of Phase 1 Awards 1991

    DTIC Science & Technology

    1991-01-01

    NAVY ABSTRACTS OF SBIR PHASE I AWARDS mmhancemegs to be added. Advanced processor architeturs which u- new technology hardware and software for...Adaptive Compensation System for Performance Improvenent of piezoelectric Hydropbones Abstract: Hydopbone output level is, in gena, insly proportional to die...growth rate is proportional to the mode frequency and under optimal conditions, the cavity mode TMI 10 exponcntiates in only 10 oscillation periods. In

  2. Optical pumping in a whispering mode optical waveguide

    DOEpatents

    Kurnit, Norman A.

    1984-01-01

    A device and method for optical pumping in a whispering mode optical waveguide. Both a helical ribbon and cylinder are disclosed which incorporate an additional curvature for confining the beam to increase intensity. An optical pumping medium is disposed in the optical path of the beam as it propagates along the waveguide. Optical pumping is enhanced by the high intensities of the beam and long interaction pathlengths which are achieved in a small volume.

  3. Coupling of small, low-loss hexapole mode with photonic crystal slab waveguide mode.

    PubMed

    Kim, Guk-Hyun; Lee, Yong-Hee; Shinya, Akihiko; Notomi, Masaya

    2004-12-27

    Coupling characteristics between the single-cell hexapole mode and the triangular-lattice photonic crystal slab waveguide mode is studied by the finite-difference time-domain method. The single-cell hexapole mode has a high quality factor (Q) of 3.3Chi106 and a small modal volume of 1.18(lambda/n)3. Based on the symmetry, three representative types of coupling geometries (shoulder-couple, butt-couple and side-couple structures) are selected and tested. The coupling efficiency shows strong dependence on the transverse overlap of the cavity mode and the waveguide mode over the region of the waveguide. The shoulder-couple structure shows best coupling characteristics among three tested structures. For example, two shouldercouple waveguides and a hexapole cavity result in a high performance resonant-tunneling-filter with Q of 9.7Chi105 and transmittance of 0.48. In the side-couple structure, the coupling strength is much weaker than that of the shoulder-couple structure because of the poor spatial overlap between the mode profiles. In the direct-couple structure, the energy transfer from the cavity to the waveguide is prohibited because of the symmetry mismatch and no coupling is observed.

  4. Coupled Groups of g-Modes in a Sun with Mixed Core

    NASA Technical Reports Server (NTRS)

    Wolff, Charles L.; ODonovan, Adam

    2007-01-01

    Groups of linear g-modes can sum to create long-lived nonlinear oscillations in small "hot volumes" very deep in the Sun that help drive the modes. In these volumes (dimensions -10 Mm), the time average rate of He-3 burning doubles as temperature fluctuations exceed 10% and rises by an order of magnitude for fluctuations of 25%. To be consistent with locally large motions, we impose a mixed shell on an otherwise standard solar model before computing g-mode solutions. Mixing in the assumed shell r = (0.10+/-0.03) R(sub sun) is rapid (<<10(exp 6) yr) with slower mixing somewhat beyond. If l is the principal spherical harmonic index, a set of g-modes for any single l less than or equal to 15 with five consecutive radial harmonics can be excited with nearly linear thermal amplitudes, A(sub T) less than or equal to 0.053, throughout the star and a fractional temperature fluctuation in its hot volume of (Delta)T/T less than or equal to 0.18. These thresholds for excitation will become smaller when sets for several values of l are computed simultaneously. There is some evidence for the rotation of g-mode sets in the long solar activity record and g-mode upward wave flux has been suggested to explain the 1.3 yr reversing flows tentatively detected below the Sun's convective envelope (CE). The large local amplitudes needed for excitation implies that g-modes may transport a non-negligible fraction of the solar luminosity, yet their near linear amplitudes outside the hot volume suggests amplitudes over most of the solar surface that would be barely detectable for l > 3. A formalism is presented for summing the g-modes and estimating growth rates under the approximation that modes are strictly linear except in a hot volume which holds only a few percent of mode kinetic energy. Finally over the range 2 less than or equal to l less than or equal to 30, we summed all zonal harmonics, m, for a given l and computed the relative angular orientations that would release the most nuclear energy. This should be close to the physically preferred angular state of such a family and a few examples were displayed.

  5. Whispering gallery mode resonators for rapid label-free biosensing in small volume droplets.

    PubMed

    Wildgen, Sarah M; Dunn, Robert C

    2015-03-23

    Rapid biosensing requires fast mass transport of the analyte to the surface of the sensing element. To optimize analysis times, both mass transport in solution and the geometry and size of the sensing element need to be considered. Small dielectric spheres, tens of microns in diameter, can act as label-free biosensors using whispering gallery mode (WGM) resonances. WGM resonances are sensitive to the effective refractive index, which changes upon analyte binding to recognition sites on functionalized resonators. The spherical geometry and tens of microns diameter of these resonators provides an efficient target for sensing while their compact size enables detection in limited volumes. Here, we explore conditions leading to rapid analyte detection using WGM resonators as label-free sensors in 10 μL sample droplets. Droplet evaporation leads to potentially useful convective mixing, but also limits the time over which analysis can be completed. We show that active droplet mixing combined with initial binding rate measurements is required for accurate nanomolar protein quantification within the first minute following injection.

  6. Raman scattering in a whispering mode optical waveguide

    DOEpatents

    Kurnit, Norman A.

    1982-01-01

    A device and method for Raman scattering in a whispering mode optical waveguide. Both a helical ribbon and cylinder are disclosed which incorporate an additional curvature .rho. p for confining the beam to increase intensity. A Raman scattering medium is disposed in the optical path of the beam as it propagates along the waveguide. Raman scattering is enhanced by the high intensities of the beam and long interaction path lengths which are achieved in a small volume.

  7. Optical pumping in a whispering-mode optical waveguide

    DOEpatents

    Kurnit, N.A.

    1981-08-11

    A device and method for optical pumping in a whispering mode optical waveguide are described. Both a helical ribbon and cylinder are disclosed which incorporate an additional curvature for confining the beam to increase intensity. An optical pumping medium is disposed in the optical path of the beam as it propagates along the waveguide. Optical pumping is enhanced by the high intensities of the beam and long interaction path lengths which are achieved in a small volume.

  8. Concentration methods for high-resolution THz spectroscopy of nucleic-acid biomolecules and crystals

    NASA Astrophysics Data System (ADS)

    Brown, E. R.; Zhang, W.; Mendoza, E. A.; Kuznetsova, Y.; Brueck, S. R. J.; Rahman, M.; Norton, M. L.

    2012-03-01

    Biomolecules can exhibit low-lying vibrational modes in the THz region which are detectable in transmission given a strong molecular dipole moment and optical depth, and a spectrometer of adequate sensitivity. The nucleic acids are particularly interesting because of applications such as label-free gene assay, bio-agent detection, etc. However for nucleic acids, sample preparation and THz coupling are of paramount importance because of the strong absorption by liquid water and the small concentration of molecules present in physiological solutions. Concentration methods become necessary to make the THz vibrational modes detectable, either by concentrating the nucleic-acid sample itself in a small volume but large area, or by concentrating the THz radiation down to the volume of the sample. This paper summarizes one type of the first method: nanofluidic channel arrays for biological nucleic acids; and two types of the second method: (1) a circular-waveguide pinhole, and (2) a circular-waveguide, conical-horn coupling structure, both for DNA crystals. The first method has been demonstrated on a very short artificial nucleic acid [small-interfering (si) RNA (17-to-25 bp)] and a much longer, biological molecule [Lambda-phage DNA (48.5 kbp)]. The second method has been demonstrated on small (~100 micron) single crystals of DNA grown by the sitting-drop method.

  9. The Angstrom Exponent and Bimodal Aerosol Size Distributions

    NASA Technical Reports Server (NTRS)

    Schuster, Gregory L.; Dubovik, Oleg; Holben, Brent H.

    2005-01-01

    Powerlaws have long been used to describe the spectral dependence of aerosol extinction, and the wavelength exponent of the aerosol extinction powerlaw is commonly referred to as the Angstrom exponent. The Angstrom exponent is often used as a qualitative indicator of aerosol particle size, with values greater than two indicating small particles associated with combustion byproducts, and values less than one indicating large particles like sea salt and dust. In this study, we investigate the relationship between the Angstrom exponent and the mode parameters of bimodal aerosol size distributions using Mie theory calculations and Aerosol Robotic Network (AERONET) retrievals. We find that Angstrom exponents based upon seven wavelengths (0.34, 0.38, 0.44, 0.5, 0.67, 0.87, and 1.02 micrometers) are sensitive to the volume fraction of aerosols with radii less then 0.6 micrometers, but not to the fine mode effective radius. The Angstrom exponent is also known to vary with wavelength, which is commonly referred to as curvature; we show how the spectral curvature can provide additional information about aerosol size distributions for intermediate values of the Angstrom exponent. Curvature also has a significant effect on the conclusions that can be drawn about two-wavelength Angstrom exponents; long wavelengths (0.67, 0.87 micrometers) are sensitive to fine mode volume fraction of aerosols but not fine mode effective radius, while short wavelengths (0.38, 0.44 micrometers) are sensitive to the fine mode effective radius but not the fine mode volume fraction.

  10. Effects of Bisphenol A on the Ovarian Transcriptome of Two Small Fish Species

    EPA Science Inventory

    Bisphenol A (BPA) is a high production volume chemical widely used in the production of polycarbonate plastics, epoxy resins, and many other commercial products. BPA has long been characterized as a xenoestrogen, and recent work suggests potential additional modes of endocrine ac...

  11. Numerical Investigation on Absorption Enhancement of Black Carbon Aerosols Partially Coated With Nonabsorbing Organics

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaolin; Mao, Mao; Yin, Yan; Wang, Bin

    2018-01-01

    This study numerically evaluates the effects of aerosol microphysics, including coated volume fraction of black carbon (BC), shell/core ratio, and size distribution, on the absorption enhancement (Eab) of polydisperse BC aggregates partially coated by organics, which is calculated by the exact multiple-sphere T-matrix method. The coated volume fraction of BC plays a substantial role in determining the absorption enhancement of partially coated BC aggregates, which typically have an Eab in the range of 1.0-2.0 with a larger value for larger coated volume fraction of BC as the shell/core ratio, BC geometry, and size distribution are fixed. The shell/core ratio, BC geometry, and size distribution have little impact on the Eab of coated BC with small coated volume fraction of BC, while they become significant for large coated volume fraction of BC. The Eab of partially coated BC particles can be slightly less than 1.0 for the large BC in the accumulation mode exhibiting large shell/core ratio and small coated volume fraction of BC, indicating that the absorption shows even slight decrease relative to uncoated BC particles. For partially coated BC aggregates in the accumulation and coarse modes, the refractive index uncertainties of BC result in the Eab differences of less than 9% and 2%, respectively, while those of organics can induce larger variations with the maximum differences up to 22% and 18%, respectively. Our study indicates that accounting for particle coating microphysics, particularly the coated volume fraction of BC, can potentially help to understand the differences in observations of largely variable absorption enhancements over various regions.

  12. Two-dimensional echo-cardiographic estimation of left atrial volume and volume load in patients with congenital heart disease.

    PubMed

    Kawaguchi, A; Linde, L M; Imachi, T; Mizuno, H; Akutsu, H

    1983-12-01

    To estimate the left atrial volume (LAV) and pulmonary blood flow in patients with congenital heart disease (CHD), we employed two-dimensional echocardiography (TDE). The LAV was measured in dimensions other than those obtained in conventional M-mode echocardiography (M-mode echo). Mathematical and geometrical models for LAV calculation using the standard long-axis, short-axis and apical four-chamber planes were devised and found to be reliable in a preliminary study using porcine heart preparations, although length (10%), area (20%) and volume (38%) were significantly and consistently underestimated with echocardiography. Those models were then applied and correlated with angiocardiograms (ACG) in 25 consecutive patients with suspected CHD. In terms of the estimation of the absolute LAV, accuracy seemed commensurate with the number of the dimensions measured. The correlation between data obtained by TDE and ACG varied with changing hemodynamics such as cardiac cycle, absolute LAV and presence or absence of volume load. The left atrium was found to become spherical and progressively underestimated with TDE at ventricular endsystole, in larger LAV and with increased volume load. Since this tendency became less pronounced in measuring additional dimensions, reliable estimation of the absolute LAV and volume load was possible when 2 or 3 dimensions were measured. Among those calculation models depending on 2 or 3 dimensional measurements, there was only a small difference in terms of accuracy and predictability, although algorithm used varied from one model to another. This suggests that accurate cross-sectional area measurement is critically important for volume estimation rather than any particular algorithm involved. Cross-sectional area measurement by TDE integrated into a three dimensional equivalent allowed a reliable estimate of the LAV or volume load in a variety of hemodynamic situations where M-mode echo was not reliable.

  13. Mechanisms of resonant low frequency Raman scattering from metallic nanoparticle Lamb modes

    NASA Astrophysics Data System (ADS)

    Girard, A.; Lermé, J.; Gehan, H.; Margueritat, J.; Mermet, A.

    2017-05-01

    The low frequency Raman scattering from gold nanoparticle bimodal assemblies with controlled size distributions has been studied. Special care has been paid to determining the size dependence of the Raman intensity corresponding to the quadrupolar Lamb mode. Existing models based on a microscopic description of the scattering mechanism in small particles (bond polarizability, dipole induced dipole models) predict, for any Raman-active Lamb modes, an inelastic intensity scaling as the volume of the nanoparticle. Surprisingly experimental intensity ratios are found to be anomalously much greater than theoretical ones, calling into question this scaling law. To explain these discrepancies, a simple mechanism of Raman scattering, based on the density fluctuations in the nanoparticles induced by the Lamb modes, is introduced. This modeling, in which the nanoparticle is described as an elastic isotropic continuous medium—as in Lamb theory, successfully explains the major features exhibited by low frequency Raman modes. Moreover this model provides a unified picture for any material, suitable for handling both small and large size ranges, as well as non-resonant and resonant excitation conditions in the case of metallic species.

  14. Evaluation of 1.0 mm i.d. column performances on ultra high pressure liquid chromatography instrumentation.

    PubMed

    Lestremau, François; Wu, Di; Szücs, Roman

    2010-07-23

    The present study focuses on the evaluation of 1.0 mm i.d. (internal diameter) columns on a commercial Ultra-High Pressure system. These systems have been developed specifically to operate columns with small volumes, typically 2.1 mm i.d., by reducing extra-column volume dispersion. The use of columns with smaller i.d. results in a reduced solvent consumption and required sample volume. The evaluation of the columns was carried out with samples containing neutral and pharmaceutical compounds. In isocratic mode, the extra-column volume produced additional band broadening leading to poor performances compared to equivalent 2.1 mm i.d. columns. By increasing the length of the column, the influence of the extra-column bandspreading could be reduced and 75,000 plates were obtained when four columns were coupled. In gradient mode, the effect of the extra-column contribution on efficiency was limited and about 80% of the performance of the 2.1 mm i.d. columns was obtained. Optimum conditions in gradient mode were further investigated by changing flow rate, gradient time and column length. A different approach of the calculation of peak capacity was also considered for the comparison of the influence of these different parameters. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  15. Unenhanced 320-row multidetector computed tomography of the brain in children: comparison of image quality and radiation dose among wide-volume, one-shot volume, and helical scan modes.

    PubMed

    Jeon, Sun Kyung; Choi, Young Hun; Cheon, Jung-Eun; Kim, Woo Sun; Cho, Yeon Jin; Ha, Ji Young; Lee, Seung Hyun; Hyun, Hyejin; Kim, In-One

    2018-04-01

    The 320-row multidetector computed tomography (CT) scanner has multiple scan modes, including volumetric modes. To compare the image quality and radiation dose of 320-row CT in three acquisition modes - helical, one-shot volume, and wide-volume scan - at pediatric brain imaging. Fifty-seven children underwent unenhanced brain CT using one of three scan modes (helical scan, n=21; one-shot volume scan, n=17; wide-volume scan, n=19). For qualitative analysis, two reviewers evaluated overall image quality and image noise using a 5-point grading system. For quantitative analysis, signal-to-noise ratio, image noise and posterior fossa artifact index were calculated. To measure the radiation dose, adjusted CT dose index per unit volume (CTDI adj ) and dose length product (DLP) were compared. Qualitatively, the wide-volume scan showed significantly less image noise than the helical scan (P=0.009), and less streak artifact than the one-shot volume scan (P=0.001). The helical mode showed significantly lower signal-to-noise ratio, with a higher image noise level compared with the one-shot volume and wide-volume modes (all P<0.05). The CTDI adj and DLP were significantly lower in the one-shot volume and wide-volume modes compared with those in the helical scan mode (all P<0.05). For pediatric unenhanced brain CT, both the wide-volume and one-shot volume scans reduced radiation dose compared to the helical scan mode, while the wide-volume scan mode showed fewer streak artifacts in the skull vertex and posterior fossa than the one-shot volume scan.

  16. LQG/LTR optimal attitude control of small flexible spacecraft using free-free boundary conditions

    NASA Astrophysics Data System (ADS)

    Fulton, Joseph M.

    Due to the volume and power limitations of a small satellite, careful consideration must be taken while designing an attitude control system for 3-axis stabilization. Placing redundancy in the system proves difficult and utilizing power hungry, high accuracy, active actuators is not a viable option. Thus, it is customary to find dependable, passive actuators used in conjunction with small scale active control components. This document describes the application of Elastic Memory Composite materials in the construction of a flexible spacecraft appendage, such as a gravity gradient boom. Assumed modes methods are used with Finite Element Modeling information to obtain the equations of motion for the system while assuming free-free boundary conditions. A discussion is provided to illustrate how cantilever mode shapes are not always the best assumption when modeling small flexible spacecraft. A key point of interest is first resonant modes may be needed in the system design plant in spite of these modes being greater than one order of magnitude in frequency when compared to the crossover frequency of the controller. LQG/LTR optimal control techniques are implemented to compute attitude control gains while controller robustness considerations determine appropriate reduced order controllers and which flexible modes to include in the design model. Key satellite designer concerns in the areas of computer processor sizing, material uncertainty impacts on the system model, and system performance variations resulting from appendage length modifications are addressed.

  17. Tuning the characteristics of surface plasmon polariton nanolasers by tailoring the dispersion relation

    NASA Astrophysics Data System (ADS)

    Lu, Tien-Chang; Chou, Yu-Hsun; Hong, Kuo-Bin; Chung, Yi-Cheng; Lin, Tzy-Rong; Arakelian, S. M.; Alodjants, A. P.

    2017-08-01

    Nanolasers with ultra-compact footprint are able to provide high intensity coherent light, which have various potential applications in high capacity signal processing, biosensing, and sub-wavelength imaging. Among various nanolasers, those lasers with cavities surrounded with metals have shown to have superior light emission properties due to the surface plasmon effect providing better field confinement capability and allowing exotic light-matter interaction. In this talk, we report robust ultraviolet ZnO nanolaser by using silver (Ag) [1] and aluminum (Al) [2] to strongly shrink the mode volume. The nanolasers operated at room temperature and even high temperature (353K) shows several distinct features including an extremely small mode volume, large Purcell factor and group index. Comparison of characteristics between Ag- and Al-based will also be made.

  18. Whispering Gallery Mode Resonators for Rapid Label-Free Biosensing in Small Volume Droplets

    PubMed Central

    Wildgen, Sarah M.; Dunn, Robert C.

    2015-01-01

    Rapid biosensing requires fast mass transport of the analyte to the surface of the sensing element. To optimize analysis times, both mass transport in solution and the geometry and size of the sensing element need to be considered. Small dielectric spheres, tens of microns in diameter, can act as label-free biosensors using whispering gallery mode (WGM) resonances. WGM resonances are sensitive to the effective refractive index, which changes upon analyte binding to recognition sites on functionalized resonators. The spherical geometry and tens of microns diameter of these resonators provides an efficient target for sensing while their compact size enables detection in limited volumes. Here, we explore conditions leading to rapid analyte detection using WGM resonators as label-free sensors in 10 μL sample droplets. Droplet evaporation leads to potentially useful convective mixing, but also limits the time over which analysis can be completed. We show that active droplet mixing combined with initial binding rate measurements is required for accurate nanomolar protein quantification within the first minute following injection. PMID:25806835

  19. Exploiting One-Dimensional Exciton-Phonon Coupling for Tunable and Efficient Single-Photon Generation with a Carbon Nanotube.

    PubMed

    Jeantet, A; Chassagneux, Y; Claude, T; Roussignol, P; Lauret, J S; Reichel, J; Voisin, C

    2017-07-12

    Condensed-matter emitters offer enriched cavity quantum electrodynamical effects due to the coupling to external degrees of freedom. In the case of carbon nanotubes, a very peculiar coupling between localized excitons and the one-dimensional acoustic phonon modes can be achieved, which gives rise to pronounced phonon wings in the luminescence spectrum. By coupling an individual nanotube to a tunable optical microcavity, we show that this peculiar exciton-phonon coupling is a valuable resource to enlarge the tuning range of the single-photon source while keeping an excellent exciton-photon coupling efficiency and spectral purity. Using the unique flexibility of our scanning fiber cavity, we are able to measure the efficiency spectrum of the very same nanotube in the Purcell regime for several mode volumes. Whereas this efficiency spectrum looks very much like the free-space luminescence spectrum when the Purcell factor is small (large mode volume), we show that the deformation of this spectrum at lower mode volumes can be traced back to the strength of the exciton-photon coupling. It shows an enhanced efficiency on the red wing that arises from the asymmetry of the incoherent energy exchange processes between the exciton and the cavity. This allows us to obtain a tuning range up to several hundred times the spectral width of the source.

  20. Squeeze strengthening of magnetorheological fluids using mixed mode operation

    NASA Astrophysics Data System (ADS)

    Becnel, A. C.; Sherman, S. G.; Hu, W.; Wereley, N. M.

    2015-05-01

    This research details a novel method of increasing the shear yield stress of magnetorheological fluids by combining shear and squeeze modes of operation to manipulate particle chain structures, so-called squeeze strengthening. Using a custom built Searle cell magnetorheometer, which is a model device emulating a rotary magnetorheological energy absorber (MREA), the contribution of squeeze strengthening to the total controllable yield force is experimentally investigated. Using an eccentric rotating inner cylinder, characterization data from large (1 mm) and small (0.25 mm) nominal gap geometries are compared to investigate the squeeze strengthening effect. Details of the experimental setup and method are presented, and a hybrid model is used to explain experimental trends. This study demonstrates that it is feasible, utilizing squeeze strengthening to increase yield stress, to either (1) design a rotary MREA of a given volume to achieve higher energy absorption density (energy absorbed normalized by active fluid volume), or (2) reduce the volume of a given rotary MREA to achieve the same energy absorption density.

  1. Characteristics of hydrogen produced by partial oxidation and auto-thermal reforming in a small methanol reformer

    NASA Astrophysics Data System (ADS)

    Horng, Rong-Fang; Chou, Huann-Ming; Lee, Chiou-Hwang; Tsai, Hsien-Te

    This paper investigates experimentally, the transient characteristics of a small methanol reformer using partial oxidation (POX) and auto-thermal reforming (ATR) for fuel cell applications. The parameters varied were heating temperature, methanol supply rate, steady mode shifting temperature, O 2/C (O 2/CH 3OH) and S/C (H 2O/CH 3OH) molar ratios with the main aim of promoting a rapid response and a high flow rate of hydrogen. The experiments showed that a high steady mode shifting temperature resulted in a faster temperature rise at the catalyst outlet and vice versa and that a low steady mode shifting temperature resulted in a lower final hydrogen concentration. However, when the mode shifting temperature was too high, the hydrogen production response was not necessarily improved. It was subsequently shown that the optimum steady mode shifting temperature for this experimental set-up was approximately 75 °C. Further, the hydrogen concentration produced by the auto-thermal process was as high as 49.12% and the volume flow rate up to 23.0 L min -1 compared to 40.0% and 20.5 L min -1 produced by partial oxidation.

  2. Cleaning procedure for improved photothermal background of toroidal optical microresonators

    NASA Astrophysics Data System (ADS)

    Horak, Erik H.; Knapper, Kassandra A.; Heylman, Kevin D.; Goldsmith, Randall H.

    2016-09-01

    High Q-factors and small mode volumes have made toroidal optical microresonators exquisite sensors to small shifts in the effective refractive index of the WGM modes. Eliminating contaminants and improving quality factors is key for many different sensing techniques, and is particularly important for photothermal imaging as contaminants add photothermal background obscuring objects of interest. Several different cleaning procedures including wet- and dry-chemical procedures are tested for their effect on Q-factors and photothermal background. RCA cleaning was shown to be successful in contrast to previously described acid cleaning procedures, most likely due to the different surface reactivity of the acid reagents used. UV-ozone cleaning was shown to be vastly superior to O2 plasma cleaning procedures, significantly reducing the photothermal background of the resonator.

  3. Observational limitations of Bose-Einstein photon statistics and radiation noise in thermal emission

    NASA Astrophysics Data System (ADS)

    Lee, Y.-J.; Talghader, J. J.

    2018-01-01

    For many decades, theory has predicted that Bose-Einstein statistics are a fundamental feature of thermal emission into one or a few optical modes; however, the resulting Bose-Einstein-like photon noise has never been experimentally observed. There are at least two reasons for this: (1) Relationships to describe the thermal radiation noise for an arbitrary mode structure have yet to be set forth, and (2) the mode and detector constraints necessary for the detection of such light is extremely hard to fulfill. Herein, photon statistics and radiation noise relationships are developed for systems with any number of modes and couplings to an observing space. The results are shown to reproduce existing special cases of thermal emission and are then applied to resonator systems to discuss physically realizable conditions under which Bose-Einstein-like thermal statistics might be observed. Examples include a single isolated cavity and an emitter cavity coupled to a small detector space. Low-mode-number noise theory shows major deviations from solely Bose-Einstein or Poisson treatments and has particular significance because of recent advances in perfect absorption and subwavelength structures both in the long-wave infrared and terahertz regimes. These microresonator devices tend to utilize a small volume with few modes, a regime where the current theory of thermal emission fluctuations and background noise, which was developed decades ago for free-space or single-mode cavities, has no derived solutions.

  4. 64 slice MDCT generally underestimates coronary calcium scores as compared to EBT: A phantom study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Greuter, M. J. W.; Dijkstra, H.; Groen, J. M.

    The objective of our study was the determination of the influence of the sequential and spiral acquisition modes on the concordance and deviation of the calcium score on 64-slice multi-detector computed tomography (MDCT) scanners in comparison to electron beam tomography (EBT) as the gold standard. Our methods and materials were an anthropomorphic cardio CT phantom with different calcium inserts scanned in sequential and spiral acquisition modes on three identical 64-slice MDCT scanners of manufacturer A and on three identical 64-slice MDCT scanners of manufacturer B and on an EBT system. Every scan was repeated 30 times with and 15 timesmore » without a small random variation in the phantom position for both sequential and spiral modes. Significant differences were observed between EBT and 64-slice MDCT data for all inserts, both acquisition modes, and both manufacturers of MDCT systems. High regression coefficients (0.90-0.98) were found between the EBT and 64-slice MDCT data for both scoring methods and both systems with high correlation coefficients (R{sup 2}>0.94). System A showed more significant differences between spiral and sequential mode than system B. Almost no differences were observed in scanners of the same manufacturer for the Agatston score and no differences for the Volume score. The deviations of the Agatston and Volume scores showed regression dependencies approximately equal to the square root of the absolute score. The Agatston and Volume scores obtained with 64-slice MDCT imaging are highly correlated with EBT-obtained scores but are significantly underestimated (-10% to -2%) for both sequential and spiral acquisition modes. System B is more independent of acquisition mode to calcium score than system A. The Volume score shows no intramanufacturer dependency and its use is advocated versus the Agatston score. Using the same cut points for MDCT-based calcium scores as for EBT-based calcium scores can result in classifying individuals into a too low risk category. System information and scanprotocol is therefore needed for every calcium score procedure to ensure a correct clinical interpretation of the obtained calcium score results.« less

  5. Acoustic modes in fluid networks

    NASA Technical Reports Server (NTRS)

    Michalopoulos, C. D.; Clark, Robert W., Jr.; Doiron, Harold H.

    1992-01-01

    Pressure and flow rate eigenvalue problems for one-dimensional flow of a fluid in a network of pipes are derived from the familiar transmission line equations. These equations are linearized by assuming small velocity and pressure oscillations about mean flow conditions. It is shown that the flow rate eigenvalues are the same as the pressure eigenvalues and the relationship between line pressure modes and flow rate modes is established. A volume at the end of each branch is employed which allows any combination of boundary conditions, from open to closed, to be used. The Jacobi iterative method is used to compute undamped natural frequencies and associated pressure/flow modes. Several numerical examples are presented which include acoustic modes for the Helium Supply System of the Space Shuttle Orbiter Main Propulsion System. It should be noted that the method presented herein can be applied to any one-dimensional acoustic system involving an arbitrary number of branches.

  6. Volume dependence of baryon number cumulants and their ratios

    DOE PAGES

    Almási, Gábor A.; Pisarski, Robert D.; Skokov, Vladimir V.

    2017-03-17

    Here, we explore the influence of finite-volume effects on cumulants of baryon/quark number fluctuations in a nonperturbative chiral model. In order to account for soft modes, we use the functional renormalization group in a finite volume, using a smooth regulator function in momentum space. We compare the results for a smooth regulator with those for a sharp (or Litim) regulator, and show that in a finite volume, the latter produces spurious artifacts. In a finite volume there are only apparent critical points, about which we compute the ratio of the fourth- to the second-order cumulant of quark number fluctuations. Finally,more » when the volume is sufficiently small the system has two apparent critical points; as the system size decreases, the location of the apparent critical point can move to higher temperature and lower chemical potential.« less

  7. A high-throughput assay format for determination of nitrate reductase and nitrite reductase enzyme activities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McNally, N.; Liu, Xiang Yang; Choudary, P.V.

    1997-01-01

    The authors describe a microplate-based high-throughput procedure for rapid assay of the enzyme activities of nitrate reductase and nitrite reductase, using extremely small volumes of reagents. The new procedure offers the advantages of rapidity, small sample size-nanoliter volumes, low cost, and a dramatic increase in the throughput sample number that can be analyzed simultaneously. Additional advantages can be accessed by using microplate reader application software packages that permit assigning a group type to the wells, recording of the data on exportable data files and exercising the option of using the kinetic or endpoint reading modes. The assay can also bemore » used independently for detecting nitrite residues/contamination in environmental/food samples. 10 refs., 2 figs.« less

  8. Pulsed laser triggered high speed microfluidic fluorescence activated cell sorter†‡

    PubMed Central

    Wu, Ting-Hsiang; Chen, Yue; Park, Sung-Yong; Hong, Jason; Teslaa, Tara; Zhong, Jiang F.; Di Carlo, Dino; Teitell, Michael A.

    2014-01-01

    We report a high speed and high purity pulsed laser triggered fluorescence activated cell sorter (PLACS) with a sorting throughput up to 20 000 mammalian cells s−1 with 37% sorting purity, 90% cell viability in enrichment mode, and >90% purity in high purity mode at 1500 cells s−1 or 3000 beads s−1. Fast switching (30 μs) and a small perturbation volume (~90 pL) is achieved by a unique sorting mechanism in which explosive vapor bubbles are generated using focused laser pulses in a single layer microfluidic PDMS channel. PMID:22361780

  9. Far-field Measurement of Ultra-Small Plasmonic Mode Volume

    DTIC Science & Technology

    2010-03-15

    Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 18. M. L. Povinelli , S. G. Johnson, M. Lonèar, M. Ibanescu, E. J. Smythe, F. Capasso, and J. D...8286–8295 (2005). 19. M. L. Povinelli , M. Loncar, M. Ibanescu, E. J. Smythe, S. G. Johnson, F. Capasso, and J. D. Joannopoulos, “Evanescent-wave

  10. Experimental determination of the particle motions associated with the low order acoustic modes in enclosures

    NASA Technical Reports Server (NTRS)

    Byrne, K. P.; Marshall, S. E.

    1983-01-01

    A procedure for experimentally determining, in terms of the particle motions, the shapes of the low order acoustic modes in enclosures is described. The procedure is based on finding differentiable functions which approximate the shape functions of the low order acoustic modes when these modes are defined in terms of the acoustic pressure. The differentiable approximating functions are formed from polynomials which are fitted by a least squares procedure to experimentally determined values which define the shapes of the low order acoustic modes in terms of the acoustic pressure. These experimentally determined values are found by a conventional technique in which the transfer functions, which relate the acoustic pressures at an array of points in the enclosure to the volume velocity of a fixed point source, are measured. The gradient of the function which approximates the shape of a particular mode in terms of the acoustic pressure is evaluated to give the mode shape in terms of the particle motion. The procedure was tested by using it to experimentally determine the shapes of the low order acoustic modes in a small rectangular enclosure.

  11. Fabrication of mirror templates in silica with micron-sized radii of curvature

    NASA Astrophysics Data System (ADS)

    Najer, Daniel; Renggli, Martina; Riedel, Daniel; Starosielec, Sebastian; Warburton, Richard J.

    2017-01-01

    We present the fabrication of exceptionally small-radius concave microoptics on fused silica substrates using CO2 laser ablation and subsequent reactive ion etching. The protocol yields on-axis near-Gaussian depressions with a radius of curvature ≲5 μm at shallow depth and low surface roughness of 2 Å. This geometry is appealing for cavity quantum electrodynamics where small mode volumes and low scattering losses are desired. We study the optical performance of the structures within a tunable Fabry-Pérot type microcavity and demonstrate near-coating-limited loss rates ( F = 25 000 ) and small focal lengths consistent with their geometrical dimensions.

  12. Dynamic effect of leachate recirculation on batch mode solid state anaerobic digestion: Influence of recirculated volume, leachate to substrate ratio and recirculation periodicity.

    PubMed

    Degueurce, Axelle; Trémier, Anne; Peu, Pascal

    2016-09-01

    Performances of batch mode solid state anaerobic digestion (SSAD) were investigated through several leachate recirculation strategies. Three parameters were shown to particularly influence methane production rates (MPR) and methane yields: the length of the interval between two recirculation events, the leachate to substrate (L:S) ratio and the volume of leachate recirculated. A central composite factor design was used to determine the influence of each parameter on methane production. Results showed that lengthening the interval between two recirculation events reduced methane yield. This effect can be counteracted by recirculating a large volume of leachate at a low L:S ratio. Steady methane production can be obtained by recirculating small amounts of leachate, and by lengthening the interval between two recirculations, regardless of the L:S ratio. However, several combinations of these parameters led to similar performances meaning that leachate recirculation practices can be modified as required by the specific constraints SSAD plants configurations. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. A numerical study on combustion process in a small compression ignition engine run dual-fuel mode (diesel-biogas)

    NASA Astrophysics Data System (ADS)

    Ambarita, H.; Widodo, T. I.; Nasution, D. M.

    2017-01-01

    In order to reduce the consumption of fossil fuel of a compression ignition (CI) engines which is usually used in transportation and heavy machineries, it can be operated in dual-fuel mode (diesel-biogas). However, the literature reviews show that the thermal efficiency is lower due to incomplete combustion process. In order to increase the efficiency, the combustion process in the combustion chamber need to be explored. Here, a commercial CFD code is used to explore the combustion process of a small CI engine run on dual fuel mode (diesel-biogas). The turbulent governing equations are solved based on finite volume method. A simulation of compression and expansions strokes at an engine speed and load of 1000 rpm and 2500W, respectively has been carried out. The pressure and temperature distributions and streamlines are plotted. The simulation results show that at engine power of 732.27 Watt the thermal efficiency is 9.05%. The experiment and simulation results show a good agreement. The method developed in this study can be used to investigate the combustion process of CI engine run on dual-fuel mode.

  14. Electromagnetic free suspension system for space manufacturing. Volume 1: Technology department

    NASA Technical Reports Server (NTRS)

    Buerger, E. H.; Frost, R. T.; Lambert, R. H.; Oconnor, M. F.; Odell, E. L. G.; Napaluch, L. J.; Stockhoff, E. H.; Wouch, G.

    1972-01-01

    The technology developed in defining a facility to be used on the Skylab mission for electromagnetic suspension of small, molten spheres in the weightless space environment is described. The technologies discussed include: four-coil optimization, four-coil versus six-coil configuration comparison, four-coil position servocontrol, four-coil breadboard, position sensing and servosystem, two-color pyrometer, and specimen toration mode analysis.

  15. About Small Streams and Shiny Rocks: Macromolecular Crystal Growth in Microfluidics

    NASA Technical Reports Server (NTRS)

    vanderWoerd, Mark; Ferree, Darren; Spearing, Scott; Monaco, Lisa; Molho, Josh; Spaid, Michael; Brasseur, Mike; Curreri, Peter A. (Technical Monitor)

    2002-01-01

    We are developing a novel technique with which we have grown diffraction quality protein crystals in very small volumes, utilizing chip-based, microfluidic ("LabChip") technology. With this technology volumes smaller than achievable with any laboratory pipette can be dispensed with high accuracy. We have performed a feasibility study in which we crystallized several proteins with the aid of a LabChip device. The protein crystals are of excellent quality as shown by X-ray diffraction. The advantages of this new technology include improved accuracy of dispensing for small volumes, complete mixing of solution constituents without bubble formation, highly repeatable recipe and growth condition replication, and easy automation of the method. We have designed a first LabChip device specifically for protein crystallization in batch mode and can reliably dispense and mix from a range of solution constituents. We are currently testing this design. Upon completion additional crystallization techniques, such as vapor diffusion and liquid-liquid diffusion will be accommodated. Macromolecular crystallization using microfluidic technology is envisioned as a fully automated system, which will use the 'tele-science' concept of remote operation and will be developed into a research facility aboard the International Space Station.

  16. A two-layer linear piezoelectric micromotor.

    PubMed

    Li, Xiaotian; Ci, Penghong; Liu, Guoxi; Dong, Shuxiang

    2015-03-01

    A first bending (B1) mode two-layer piezoelectric ultrasonic linear micromotor has been developed for microoptics driving applications. The piezo-vibrator of the micromotor was composed of two small Pb(Zr,Ti)O3 (PZT-5) plates, with overall dimensions and mass of only 2.0 × 2.0 × 5.0 mm(3) and 0.2 g, respectively. The proposed micromotor could operate either in single-phase voltage (standing wave) mode or two-phase voltage (traveling wave) mode to drive a slider via friction force to provide bidirectional linear motion. A large thrust of up to 0.30 N, which corresponds to a high unit volume direct driving force of 15 mN/mm(3), and a linear movement velocity of up to 230 mm/s were obtained under an applied voltage of 80 Vpp at the B1 mode resonance frequency of 174 kHz.

  17. Influence of a depletion interaction on dynamical heterogeneity in a dense quasi-two-dimensional colloid liquid.

    PubMed

    Ho, Hau My; Cui, Bianxiao; Repel, Stephen; Lin, Binhua; Rice, Stuart A

    2004-11-01

    We report the results of digital video microscopy studies of the large particle displacements in a quasi-two-dimensional binary mixture of large (L) and small (S) colloid particles with diameter ratio sigma(L)/sigma(S)=4.65, as a function of the large and small colloid particle densities. As in the case of the one-component quasi-two-dimensional colloid system, the binary mixtures exhibit structural and dynamical heterogeneity. The distribution of large particle displacements over the time scale examined provides evidence for (at least) two different mechanisms of motion, one associated with particles in locally ordered regions and the other associated with particles in locally disordered regions. When rhoL*=Npisigma(L) (2)/4A< or =0.35, the addition of small colloid particles leads to a monotonic decrease in the large particle diffusion coefficient with increasing small particle volume fraction. When rhoL* > or =0.35 the addition of small colloid particles to a dense system of large colloid particles at first leads to an increase in the large particle diffusion coefficient, which is then followed by the expected decrease of the large particle diffusion coefficient with increasing small colloid particle volume fraction. The mode coupling theory of the ideal glass transition in three-dimensional systems makes a qualitative prediction that agrees with the initial increase in the large particle diffusion coefficient with increasing small particle density. Nevertheless, because the structural and dynamical heterogeneities of the quasi-two-dimensional colloid liquid occur within the field of equilibrium states, and the fluctuations generate locally ordered domains rather than just disordered regions of higher and lower density, it is suggested that mode coupling theory does not account for all classes of relevant fluctuations in a quasi-two-dimensional liquid. (c) 2004 American Institute of Physics.

  18. Optimisation des proprietes physiques d'un composite carbone epoxy fabrique par le procede RFI

    NASA Astrophysics Data System (ADS)

    Koanda, Mahamat Mamadou Lamine

    The RFI (Resin Film Infusion) process is a composite materials manufacturing process. Especially known for the small investment it requires, RFI processes are more and more widely used in the aeronautical industry. However a number of aspects of this process are still not well controlled. The quality of the final part depends on which process is used. In the case of RFI, controlling physical characteristics such as thickness, fiber volume fraction or void content remains a major challenge. This dissertation deals with the optimization of the physical properties of a carbon composite manufactured with RFI processes. The ASTMD3171 and ASTMD792 standards were used to measure the void content and fiber volume fraction. First, we introduced different layup sequences in the RFI process and evaluate their impact on the physical properties of the final product. The experiments show the primary mode A, with the resin film at the bottom, resulting in much better quality with controlled fiber volume fraction and void content. Mode B (film in the symmetrical plane) yields results identical to mode A except more irregular thicknesses. Mode C (symmetrical film in the laminate) produces locally unacceptable void contents. Mode D (resin film on the top of the laminate) yields much better results than mode A with the exception of the more irregular thicknesses. Making gaps and overlaps with the resin film has negative effects beyond 2.54cm (one inch) and should be avoided. Several C-scan observations of the manufactured samples showed a large accumulation of porosity in the resin rich areas, as well as surface defects. Ultimately we analyzed the cure cycle in light of the thermodynamic porosity models. It is evident that the diffusion phenomenon is essential in this process. Therefore a better conditioning of the resin film made by Cytec is required. An optimal design with a cycle stop and pressure lag yields the optimal cure cycle for the RFI process.

  19. Compact Reconfigurable Antenna with an Omnidirectional Pattern and Four Directional Patterns for Wireless Sensor Systems.

    PubMed

    Wang, Ren; Wang, Bing-Zhong; Huang, Wei-Ying; Ding, Xiao

    2016-04-16

    A compact reconfigurable antenna with an omnidirectional mode and four directional modes is proposed. The antenna has a main radiator and four parasitic elements printed on a dielectric substrate. By changing the status of diodes soldered on the parasitic elements, the proposed antenna can generate four directional radiation patterns and one omnidirectional radiation pattern. The main beam directions of the four directional modes are almost orthogonal and the four directional beams can jointly cover a 360° range in the horizontal plane, i.e., the main radiation plane of omnidirectional mode. The whole volume of the antenna and the control network is approximately 0.70 λ × 0.53 λ × 0.02 λ, where λ is the wavelength corresponding to the center frequency. The proposed antenna has a simple structure and small dimensions under the requirement that the directional radiation patterns can jointly cover the main radiation plane of the omnidirectional mode, therefore, it can be used in smart wireless sensor systems for different application scenarios.

  20. On-Chip High-Finesse Fabry-Perot Microcavities for Optical Sensing and Quantum Information.

    PubMed

    Bitarafan, Mohammad H; DeCorby, Ray G

    2017-07-31

    For applications in sensing and cavity-based quantum computing and metrology, open-access Fabry-Perot cavities-with an air or vacuum gap between a pair of high reflectance mirrors-offer important advantages compared to other types of microcavities. For example, they are inherently tunable using MEMS-based actuation strategies, and they enable atomic emitters or target analytes to be located at high field regions of the optical mode. Integration of curved-mirror Fabry-Perot cavities on chips containing electronic, optoelectronic, and optomechanical elements is a topic of emerging importance. Micro-fabrication techniques can be used to create mirrors with small radius-of-curvature, which is a prerequisite for cavities to support stable, small-volume modes. We review recent progress towards chip-based implementation of such cavities, and highlight their potential to address applications in sensing and cavity quantum electrodynamics.

  1. On-Chip High-Finesse Fabry-Perot Microcavities for Optical Sensing and Quantum Information

    PubMed Central

    Bitarafan, Mohammad H.; DeCorby, Ray G.

    2017-01-01

    For applications in sensing and cavity-based quantum computing and metrology, open-access Fabry-Perot cavities—with an air or vacuum gap between a pair of high reflectance mirrors—offer important advantages compared to other types of microcavities. For example, they are inherently tunable using MEMS-based actuation strategies, and they enable atomic emitters or target analytes to be located at high field regions of the optical mode. Integration of curved-mirror Fabry-Perot cavities on chips containing electronic, optoelectronic, and optomechanical elements is a topic of emerging importance. Micro-fabrication techniques can be used to create mirrors with small radius-of-curvature, which is a prerequisite for cavities to support stable, small-volume modes. We review recent progress towards chip-based implementation of such cavities, and highlight their potential to address applications in sensing and cavity quantum electrodynamics. PMID:28758967

  2. Cost characteristics of tilt-rotor, conventional air and high speed rail short-haul intercity passenger service

    NASA Technical Reports Server (NTRS)

    Schoendorfer, David L.; Morlok, Edward K.

    1985-01-01

    The cost analysis done to support an assessment of the potential for a small tilt-rotor aircraft to operate in short-haul intercity passenger service is described in detail. Anticipated costs of tilt-rotor air service were compared to the costs of two alternatives: conventional air and high speed rail (HSR). Costs were developed for corridor service, varying key market characteristics including distance, passenger volumes, and minimum frequency standards. The resulting cost vs output information can then be used to compare modal costs for essentially identical service quality and passenger volume or for different service levels and volumes for each mode, as appropriate. Extensive sensitivity analyses are performed. The cost-output features of these technologies are compared. Tilt-rotor is very attractive compared to HSR in terms of costs over the entire range of volume. It also has costs not dramatically different from conventional air, but tilt-rotor costs are generally higher. Thus some of its other advantages, such as the VTOL capability, must offset the cost disadvantage for it to be a preferred or competitive mode in any given market. These issues are addressed in the companion report which considers strategies for tilt-rotor development in commercial air service.

  3. Feasibility of Standardized Rain Testing for Fuzes. Serial Number 1.0

    DTIC Science & Technology

    1981-06-01

    produced by ;he drops in a small volume with a laser beam. /, -- Il 8’ 15𔃻 -. - II11,, I - - Il i Io " illli A pr c i / con3 1de at o Is sh ll d o u d r...of collapse of the spherical bubbles in an asymmetric mode such that hlqh velocity microjets impinqe on the surface. It appears cavitation microjet

  4. Exact mode volume and Purcell factor of open optical systems

    NASA Astrophysics Data System (ADS)

    Muljarov, E. A.; Langbein, W.

    2016-12-01

    The Purcell factor quantifies the change of the radiative decay of a dipole in an electromagnetic environment relative to free space. Designing this factor is at the heart of photonics technology, striving to develop ever smaller or less lossy optical resonators. The Purcell factor can be expressed using the electromagnetic eigenmodes of the resonators, introducing the notion of a mode volume for each mode. This approach allows an analytic treatment, reducing the Purcell factor and other observables to sums over eigenmode resonances. Calculating the mode volumes requires a correct normalization of the modes. We introduce an exact normalization of modes, not relying on perfectly matched layers. We present an analytic theory of the Purcell effect based on this exact mode normalization and the resulting effective mode volume. We use a homogeneous dielectric sphere in vacuum, which is analytically solvable, to exemplify these findings. We furthermore verify the applicability of the normalization to numerically determined modes of a finite dielectric cylinder.

  5. Detecting single viruses and nanoparticles using whispering gallery microlasers.

    PubMed

    He, Lina; Ozdemir, Sahin Kaya; Zhu, Jiangang; Kim, Woosung; Yang, Lan

    2011-06-26

    There is a strong demand for portable systems that can detect and characterize individual pathogens and other nanoscale objects without the use of labels, for applications in human health, homeland security, environmental monitoring and diagnostics. However, most nanoscale objects of interest have low polarizabilities due to their small size and low refractive index contrast with the surrounding medium. This leads to weak light-matter interactions, and thus makes the label-free detection of single nanoparticles very difficult. Micro- and nano-photonic devices have emerged as highly sensitive platforms for such applications, because the combination of high quality factor Q and small mode volume V leads to significantly enhanced light-matter interactions. For example, whispering gallery mode microresonators have been used to detect and characterize single influenza virions and polystyrene nanoparticles with a radius of 30 nm (ref. 12) by measuring in the transmission spectrum either the resonance shift or mode splitting induced by the nanoscale objects. Increasing Q leads to a narrower resonance linewidth, which makes it possible to resolve smaller changes in the transmission spectrum, and thus leads to improved performance. Here, we report a whispering gallery mode microlaser-based real-time and label-free detection method that can detect individual 15-nm-radius polystyrene nanoparticles, 10-nm gold nanoparticles and influenza A virions in air, and 30 nm polystyrene nanoparticles in water. Our approach relies on measuring changes in the beat note that is produced when an ultra-narrow emission line from a whispering gallery mode microlaser is split into two modes by a nanoscale object, and these two modes then interfere. The ultimate detection limit is set by the laser linewidth, which can be made much narrower than the resonance linewidth of any passive resonator. This means that microlaser sensors have the potential to detect objects that are too small to be detected by passive resonator sensors.

  6. Mathematical and computational studies of the stability of axisymmetric annular capillary free surfaces

    NASA Technical Reports Server (NTRS)

    Albright, N.; Concus, P.; Karasalo, I.

    1977-01-01

    Of principal interest is the stability of a perfectly wetting liquid in an inverted, vertical, right circular-cylindrical container having a concave spheroidal bottom. The mathematical conditions that the contained liquid be in stable static equilibrium are derived, including those for the limiting case of zero contact angle. Based on these results, a computational investigation is carried out for a particular container that is used for the storage of liquid fuels in NASA Centaur space vehicles, for which the axial ratio of the container bottom is 0.724. It is found that for perfectly wetting liquids the qualitative nature of the onset of instability changes at a critical liquid volume, which for the Centaur fuel tank corresponds to a mean fill level of approximately 0.503 times the tank's radius. Small-amplitude periodic sloshing modes for this tank were calculated; oscillation frequencies or growth rates are given for several Bond numbers and liquid volumes, for normal modes having up to six angular nodes.

  7. Determination of dioxin-like polychlorinated biphenyls in 1 mL whole blood using programmable temperature vaporization large volume injection coupled to gas chromatogram and high-resolution mass spectrometry.

    PubMed

    Shen, Haitao; Guan, Rongfa; Li, Jingguang; Zhang, Lei; Ren, Yiping; Xu, Xiaomin; Song, Yang; Zhao, Yunfeng; Han, Jianlong; Wu, Yongning

    2013-03-12

    A sensitive method based on programmable temperature vaporization large volume injection coupled to gas chromatogram and high-resolution mass spectrometry (PTV-GC-HRMS) has been developed for the determination of ultra trace levels of dioxin-like polychlorinated biphenyls (DL PCBs) in small amounts of human blood. Blood samples (1mL) were first extracted by column extraction and then purified with column chromatorgraphies. Final extracts (20μL) were introduced to the PTV injector under the solvent vent mode and detected by GC-HRMS (SIM mode). PTV parameters were observed by changing one factor at a time (practical conditions: vent flow: 50mLmin(-1), vent pressure: 0kPa and vent time: 0.1min), recoveries of most PCB congeners ranged from 55.1% to 108%, and method detection limits were in the range of 0.11-1.63pgg(-1). Copyright © 2013 Elsevier B.V. All rights reserved.

  8. Chip Scale Ultra-Stable Clocks: Miniaturized Phonon Trap Timing Units for PNT of CubeSats

    NASA Technical Reports Server (NTRS)

    Rais-Zadeh, Mina; Altunc, Serhat; Hunter, Roger C.; Petro, Andrew

    2016-01-01

    The Chip Scale Ultra-Stable Clocks (CSUSC) project aims to provide a superior alternative to current solutions for low size, weight, and power timing devices. Currently available quartz-based clocks have problems adjusting to the high temperature and extreme acceleration found in space applications, especially when scaled down to match small spacecraft size, weight, and power requirements. The CSUSC project aims to utilize dual-mode resonators on an ovenized platform to achieve the exceptional temperature stability required for these systems. The dual-mode architecture utilizes a temperature sensitive and temperature stable mode simultaneously driven on the same device volume to eliminate ovenization error while maintaining extremely high performance. Using this technology it is possible to achieve parts-per-billion (ppb) levels of temperature stability with multiple orders of magnitude smaller size, weight, and power.

  9. Nonlinear response of silicon photonic crystal microresonators excited via an integrated waveguide and fiber taper.

    PubMed

    Barclay, Paul; Srinivasan, Kartik; Painter, Oskar

    2005-02-07

    A technique is demonstrated which efficiently transfers light between a tapered standard single-mode optical fiber and a high-Q, ultra-small mode volume, silicon photonic crystal resonant cavity. Cavity mode quality factors of 4.7x10(4) are measured, and a total fiber-to-cavity coupling efficiency of 44% is demonstrated. Using this efficient cavity input and output channel, the steady-state nonlinear absorption and dispersion of the photonic crystal cavity is studied. Optical bistability is observed for fiber input powers as low as 250 microW, corresponding to a dropped power of 100 microW and 3 fJ of stored cavity energy. A high-density effective free-carrier lifetime for these silicon photonic crystal resonators of ~ 0.5 ns is also estimated from power dependent loss and dispersion measurements.

  10. Enhancement of Raman scattering from monolayer graphene by photonic crystal nanocavities

    NASA Astrophysics Data System (ADS)

    Kimura, Issei; Yoshida, Masahiro; Sota, Masaki; Inoue, Taiki; Chiashi, Shohei; Maruyama, Shigeo; Kato, Yuichiro K.

    Monolayer graphene is an atomically thin two-dimensional material that shows strong Raman scattering, while photonic crystal nanocavities with small mode volumes allow for efficient optical coupling at the nanoscale. Here we demonstrate resonant enhancement of graphene Raman G' band by coupling to photonic crystal cavity modes. Hexagonal-lattice photonic crystal L3 cavities are fabricated from silicon-on-insulator substrates. and monolayer graphene sheets grown by chemical vapor deposition are transferred onto the nanocavities. Excitation wavelength dependence of Raman spectra show that the Raman intensity is enhanced when the G' peak is in resonance with the cavity mode. By performing imaging measurements, we confirm that such an enhancement is only observed at the cavity position. Work supported by JSPS KAKENHI Grant Numbers JP16K13613, JP25107002 and MEXT (Photon Frontier Network Program, Nanotechnology Platform).

  11. Chemical consequences of the initial diffusional growth of cloud droplets - A clean marine case

    NASA Technical Reports Server (NTRS)

    Twohy, C. H.; Charlson, R. J.; Austin, P. H.

    1989-01-01

    A simple microphysical cloud parcel model and a simple representation of the background marine aerosol are used to predict the concentrations and compositions of droplets of various sizes near cloud base. The aerosol consists of an externally-mixed ammonium bisulfate accumulation mode and a sea-salt coarse particle mode. The difference in diffusional growth rates between the small and large droplets as well as the differences in composition between the two aerosol modes result in substantial differences in solute concentration and composition with size of droplets in the parcel. The chemistry of individual droplets is not, in general, representative of the bulk (volume-weighted mean) cloud water sample. These differences, calculated to occur early in the parcel's lifetime, should have important consequences for chemical reactions such as aqueous phase sulfate production.

  12. Dynamic System Coupler Program (DYSCO 4.1). Volume 1. Theoretical Manual

    DTIC Science & Technology

    1989-01-01

    present analysis is as follows: 1. Triplet X, Y, Z represents an inertia frame, R. The R system coordinates are the rotor shaft axes when there is...small perturbation analysis . 2.5 3-D MODAL STRUCTURE - CFM3 A three-dimensional structure is represented as a linear combination of orth­ ogonal modes...Include rotor blade damage modeling, Elgen analysis development, general time history solution development, frequency domain solution development

  13. A Resonator for Low-Threshold Frequency Conversion

    NASA Technical Reports Server (NTRS)

    Iltchenko, Vladimir; Matsko, Andrey; Savchenkov, Anatoliy; Maleki, Lute

    2004-01-01

    A proposed toroidal or disklike dielectric optical resonator (dielectric optical cavity) would be made of an optically nonlinear material and would be optimized for use in parametric frequency conversion by imposition of a spatially periodic permanent electric polarization. The poling (see figure) would suppress dispersions caused by both the material and the geometry of the optical cavity, thereby effecting quasi-matching of the phases of high-resonance-quality (high-Q) whispering-gallery electromagnetic modes. The quasi-phase-matching of the modes would serve to maximize the interactions among them. Such a resonator might be a prototype of a family of compact, efficient nonlinear devices for operation over a broad range of optical wavelengths. A little background information is prerequisite to a meaningful description of this proposal: (1) Described in several prior NASA Tech Briefs articles, the whispering-gallery modes in a component of spheroidal, disklike, or toroidal shape are waveguide modes that propagate circumferentially and are concentrated in a narrow toroidal region centered on the equatorial plane and located near the outermost edge. (2) For the sake of completeness, it must be stated that even though optical resonators of the type considered here are solid dielectric objects and light is confined within them by total internal reflection at dielectric interfaces without need for mirrors, such components are sometimes traditionally called cavities because their effects upon the light propagating within them are similar to those of true cavities bounded by mirrors. (3) For a given set of electromagnetic modes interacting with each other in an optically nonlinear material (e.g., modes associated with the frequencies involved in a frequency-conversion scheme), the threshold power for oscillation depends on the mode volumes and the mode-overlap integral. (4) Whispering-gallery modes are attractive in nonlinear optics because they maximize the effects of nonlinearities by occupying small volumes and affording high Q values

  14. Plasmonic photonic crystals realized through DNA-programmable assembly

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Park, Daniel J.; Zhang, Chuan; Ku, Jessie C.

    Three-dimensional dielectric photonic crystals have well-established enhanced light-matter interactions via high Q factors. Their plasmonic counterparts based on arrays of nanoparticles, however, have not been experimentally well explored owing to a lack of available synthetic routes for preparing them. However, such structures should facilitate these interactions based on the small mode volumes associated with plasmonic polarization. Herein we report strong light-plasmon interactions within 3D plasmonic photonic crystals that have lattice constants and nanoparticle diameters that can be independently controlled in the deep subwavelength size regime by using a DNA-programmable assembly technique. The strong coupling within such crystals is probed withmore » backscattering spectra, and the mode splitting (0.10 and 0.24 eV) is defined based on dispersion diagrams. Numerical simulations predict that the crystal photonic modes (Fabry-Perot modes) can be enhanced by coating the crystals with a silver layer, achieving moderate Q factors (~102) over the visible and near-infrared spectrum.« less

  15. Plasmonic photonic crystals realized through DNA-programmable assembly

    DOE PAGES

    Park, Daniel J.; Zhang, Chuan; Ku, Jessie C.; ...

    2014-12-29

    Three-dimensional dielectric photonic crystals have well-established enhanced light-matter interactions via high Q factors. Their plasmonic counterparts based on arrays of nanoparticles, however, have not been experimentally well explored owing to a lack of available synthetic routes for preparing them. However, such structures should facilitate these interactions based on the small mode volumes associated with plasmonic polarization. Herein we report strong light-plasmon interactions within 3D plasmonic photonic crystals that have lattice constants and nanoparticle diameters that can be independently controlled in the deep subwavelength size regime by using a DNA-programmable assembly technique. The strong coupling within such crystals is probed withmore » backscattering spectra, and the mode splitting (0.10 and 0.24 eV) is defined based on dispersion diagrams. Numerical simulations predict that the crystal photonic modes (Fabry-Perot modes) can be enhanced by coating the crystals with a silver layer, achieving moderate Q factors (~102) over the visible and near-infrared spectrum.« less

  16. Plasmonic photonic crystals realized through DNA-programmable assembly

    PubMed Central

    Park, Daniel J.; Zhang, Chuan; Ku, Jessie C.; Zhou, Yu; Schatz, George C.; Mirkin, Chad A.

    2015-01-01

    Three-dimensional dielectric photonic crystals have well-established enhanced light–matter interactions via high Q factors. Their plasmonic counterparts based on arrays of nanoparticles, however, have not been experimentally well explored owing to a lack of available synthetic routes for preparing them. However, such structures should facilitate these interactions based on the small mode volumes associated with plasmonic polarization. Herein we report strong light-plasmon interactions within 3D plasmonic photonic crystals that have lattice constants and nanoparticle diameters that can be independently controlled in the deep subwavelength size regime by using a DNA-programmable assembly technique. The strong coupling within such crystals is probed with backscattering spectra, and the mode splitting (0.10 and 0.24 eV) is defined based on dispersion diagrams. Numerical simulations predict that the crystal photonic modes (Fabry–Perot modes) can be enhanced by coating the crystals with a silver layer, achieving moderate Q factors (∼102) over the visible and near-infrared spectrum. PMID:25548175

  17. Plasmonic photonic crystals realized through DNA-programmable assembly.

    PubMed

    Park, Daniel J; Zhang, Chuan; Ku, Jessie C; Zhou, Yu; Schatz, George C; Mirkin, Chad A

    2015-01-27

    Three-dimensional dielectric photonic crystals have well-established enhanced light-matter interactions via high Q factors. Their plasmonic counterparts based on arrays of nanoparticles, however, have not been experimentally well explored owing to a lack of available synthetic routes for preparing them. However, such structures should facilitate these interactions based on the small mode volumes associated with plasmonic polarization. Herein we report strong light-plasmon interactions within 3D plasmonic photonic crystals that have lattice constants and nanoparticle diameters that can be independently controlled in the deep subwavelength size regime by using a DNA-programmable assembly technique. The strong coupling within such crystals is probed with backscattering spectra, and the mode splitting (0.10 and 0.24 eV) is defined based on dispersion diagrams. Numerical simulations predict that the crystal photonic modes (Fabry-Perot modes) can be enhanced by coating the crystals with a silver layer, achieving moderate Q factors (∼10(2)) over the visible and near-infrared spectrum.

  18. Compact Reconfigurable Antenna with an Omnidirectional Pattern and Four Directional Patterns for Wireless Sensor Systems

    PubMed Central

    Wang, Ren; Wang, Bing-Zhong; Huang, Wei-Ying; Ding, Xiao

    2016-01-01

    A compact reconfigurable antenna with an omnidirectional mode and four directional modes is proposed. The antenna has a main radiator and four parasitic elements printed on a dielectric substrate. By changing the status of diodes soldered on the parasitic elements, the proposed antenna can generate four directional radiation patterns and one omnidirectional radiation pattern. The main beam directions of the four directional modes are almost orthogonal and the four directional beams can jointly cover a 360° range in the horizontal plane, i.e., the main radiation plane of omnidirectional mode. The whole volume of the antenna and the control network is approximately 0.70 λ × 0.53 λ × 0.02 λ, where λ is the wavelength corresponding to the center frequency. The proposed antenna has a simple structure and small dimensions under the requirement that the directional radiation patterns can jointly cover the main radiation plane of the omnidirectional mode, therefore, it can be used in smart wireless sensor systems for different application scenarios. PMID:27092512

  19. Axisymmetric oscillation modes of a double droplet system

    DOE PAGES

    Ramalingam, Santhosh K.; Basaran, Osman A.

    2010-11-15

    A double droplet system (DDS) consists of a sessile and a pendant drop that are coupled through a liquid filled cylindrical hole in a plate of thickness d. For a small hole radius R, equilibrium shapes of both drops are sections of spheres. While DDSs have a number of applications in microfluidics, a DDS oscillating about its equilibrium state can be used as a fast focusing liquid lens. Here, a DDS consisting of an isothermal, incompressible Newtonian fluid of constant density p and constant viscosity u that is surrounded by a gas is excited by oscillating in time (a) themore » pressure in the gas surrounding either drop (pressure excitation), (b) the plate perpendicular to its plane (axial excitation), and (c) the hole radius (radial excitation). In contrast to previous works that assumed transient drop shapes are spherical, they are determined here by simulation and used to identify the natural modes of axisymmetric oscillations from resonances observed during frequency sweeps with DDSs for which the combined volume V of the two drops is less than (4/3)πR 3. Pressure and axial excitations are found to have identical responses but axial and radial excitations are shown to excite different modes. These modes are compared to those exhibited by single pendant (sessile) drop systems. Specifically, while a single pendant (sessile) drop has one additional oscillation mode compared to a free drop, a DDS is found to exhibit roughly twice as many oscillation modes as a pendant (sessile) drop. The effects of dimensionless volume V/R 3, dimensionless plate thickness d/R, and Ohnesorge number Oh =μ/√ρRσ , where σ is the surface tension of the DDS-gas interface, on the resonance frequencies are also investigated.« less

  20. New stereotactic X-ray knife

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barish, R.J.; Barish, S.V.

    1988-06-01

    For many years, the irradiation of small volumes of tissue in the brain to necrotizing doses has been investigated as a non-invasive alternative to neurosurgery. We propose a new system in which a precisely machined helmet serves as a multi-port focussed X-ray collimator when it is itself irradiated by a conventional medical linear accelerator run in the electron mode. When the collimator is attached to a stereotactic frame, the geometric accuracy of delivering small radiation fields to the brain is limited primarily by the accuracy of the stereotactic localization, and is relatively independent of the positional stability of the accelerator.more » Field sizes as small as two millimeters are readily achievable. The problem of low dose rate associated with these small fields is overcome by the use of high electron beam currents.« less

  1. Electromagnetic radiation in a semi-compact space

    NASA Astrophysics Data System (ADS)

    Iso, Satoshi; Kitazawa, Noriaki; Yokoo, Sumito

    2018-02-01

    In this note, we investigate the electromagnetic radiation emitted from a revolving point charge in a compact space. If the point charge is circulating with an angular frequency ω0 on the (x , y)-plane at z = 0 with boundary conditions, x ∼ x + 2 πR and y ∼ y + 2 πR, it emits radiation into the z-direction of z ∈ [ - ∞ , + ∞ ]. We find that the radiation shows discontinuities as a function of ω0 R at which a new propagating mode with a different Fourier component appears. For a small radius limit ω0 R ≪ 1, all the Fourier modes except the zero mode on (x , y)-plane are killed, but an effect of squeezing the electric field totally enhances the radiation. In the large volume limit ω0 R → ∞, the energy flux of the radiation reduces to the expected Larmor formula.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pellicer-Porres, J., E-mail: Julio.Pellicer@uv.es; Segura, A.; Santamaría-Pérez, D.

    We have measured high pressure α-quartz reflectance spectra in the mid infrared. We used single crystals, taking full profit of polarization. The quality of the spectra allows fitting the reflectance spectra. We have characterized the pressure evolution of E and A{sub 2} modes with increased precision, even in the spectral regions where they overlap. In addition, we have determined the TO-LO splitting of each mode. Some of the A{sub 2} modes show dramatic pressure variations of the LO-TO splitting, which cannot be explained only by changes in length and ionicity of individual bonds, requiring a new mechanism. We suggest thatmore » rotation of the SiO{sub 4} tetrahedra plays a fundamental role. We have also determined the evolution of the electronic dielectric constant under high pressure. We find that its pressure increment is mainly a volume effect, although the small increase in birefringence points to secondary changes associated to the electronic resonances.« less

  3. Aero-Hydroacoustics for Ships. Volume 1

    DTIC Science & Technology

    1984-06-01

    as 10 and bubble radii as small as 20 t.m. Thl’ use of acoustic a) sorption (it is also possible to measure the reduction of 5-,L’nd sJ L~d in bubbly... pFA -(2,0 1 0 12 3 456 km V’,r~ (20") *Figure 6.20 -Wave Number Locus for 1.5 x 0.6 x 0.0254 Meter Panel at f= 4180 Hertz; Half-Integer Modes are those

  4. Impact of large-scale tides on cosmological distortions via redshift-space power spectrum

    NASA Astrophysics Data System (ADS)

    Akitsu, Kazuyuki; Takada, Masahiro

    2018-03-01

    Although large-scale perturbations beyond a finite-volume survey region are not direct observables, these affect measurements of clustering statistics of small-scale (subsurvey) perturbations in large-scale structure, compared with the ensemble average, via the mode-coupling effect. In this paper we show that a large-scale tide induced by scalar perturbations causes apparent anisotropic distortions in the redshift-space power spectrum of galaxies in a way depending on an alignment between the tide, wave vector of small-scale modes and line-of-sight direction. Using the perturbation theory of structure formation, we derive a response function of the redshift-space power spectrum to large-scale tide. We then investigate the impact of large-scale tide on estimation of cosmological distances and the redshift-space distortion parameter via the measured redshift-space power spectrum for a hypothetical large-volume survey, based on the Fisher matrix formalism. To do this, we treat the large-scale tide as a signal, rather than an additional source of the statistical errors, and show that a degradation in the parameter is restored if we can employ the prior on the rms amplitude expected for the standard cold dark matter (CDM) model. We also discuss whether the large-scale tide can be constrained at an accuracy better than the CDM prediction, if the effects up to a larger wave number in the nonlinear regime can be included.

  5. Propagation of magnetostatic spin waves in an yttrium iron garnet film for out-of-plane magnetic fields

    NASA Astrophysics Data System (ADS)

    Bang, Wonbae; Lim, Jinho; Trossman, Jonathan; Tsai, C. C.; Ketterson, John B.

    2018-06-01

    We have observed the propagation of spin waves across a thin yttrium iron garnet film on (1 1 1) gadolinium gallium garnet for magnetic fields inclined with respect to the film plane. Two principle planes were studied: that for H in the plane defined by the wave vector k and the plane normal, n, with limiting forms corresponding to the Backward Volume and Forward Volume modes, and that for H in the plane perpendicular to k, with limiting forms corresponding to the Damon-Eshbach and Forward Volume modes. By exciting the wave at one edge of the film and observing the field dependence of the phase of the received signal at the opposing edge we determined the frequency vs. wavevector relation, ω = ω (k), of various propagating modes in the film. Avoided crossings are observed in the Damon-Eshbach and Forward Volume regimes when the propagating mode intersects the higher, exchange split, volume modes, leading to an extinction of the propagating mode; analysis of the resulting behavior allows a determination of the exchange parameter. The experimental results are compared with theoretical simulations.

  6. Interfacial diffusion aided deformation during nanoindentation

    DOE PAGES

    Samanta, Amit; E., Weinan

    2015-07-06

    Nanoindentation is commonly used to quantify the mechanical response of material surfaces. Despite its widespread use, a detailed understanding of the deformation mechanisms responsible for plasticity during these experiments has remained elusive. Nanoindentation measurements often show stress values close to a material’s ideal strength which suggests that dislocation nucleation and subsequent dislocation activity dominates the deformation. However, low strain-rate exponents and small activation volumes have also been reported which indicates high temperature sensitivity of the deformation processes. Using an order parameter aided temperature accelerated sampling technique called adiabatic free energy dynamics [J. B. Abrams and M. E. Tuckerman, J. Phys.more » Chem. B, 112, 15742 (2008)], and molecular dynamics we have probed the diffusive mode of deformation during nanoindentation. Localized processes such as surface vacancy and ad-atom pair formation, vacancy diffusion are found to play an important role during indentation. Furthermore, our analysis suggests a change in the dominant deformation mode from dislocation mediated plasticity to diffusional flow at high temperatures, slow indentation rates and small indenter tip radii.« less

  7. Enhancement of fiber-optic low-coherence Fabry-Pérot interferometer with ZnO ALD films

    NASA Astrophysics Data System (ADS)

    Hirsch, Marzena; Listewnik, Paulina; Jedrzejewska-Szczerska, Małgorzata

    2018-04-01

    In this paper investigation of the enhanced fiber-optic low coherence Fabry-Pérot interferometer with zinc oxide (ZnO) film deposited by atomic layer deposition (ALD) was presented. Model of the interferometer, which was constructed of single-mode optical fiber with applied ZnO ALD films, was built. The interferometer was also examined by means of experiment. Measurements were performed for both reflective and transmission modes, using wavelengths of 1300 nm and 1500 nm. The measurements with the air cavity showed the best performance in terms of a visibility of the interference signal can be achieved for small cavity lengths ( 50μm) in both configurations. Combined with the enhancement of reflectance of the interferometer mirrors due to the ALD film, proposed construction could be successfully applied in refractive index (RI) sensor that can operate with improved visibility of the signal even in 1.3-1.5 RI range as well as with small volume samples, as shown by the modeling.

  8. Experimental Spin Testing of Integrally Damped Composite Plates

    NASA Technical Reports Server (NTRS)

    Kosmatka, John

    1998-01-01

    The experimental behavior of spinning laminated composite pretwisted plates (turbo-fan blade-like) with small (less than 10% by volume) integral viscoelastic damping patches was investigated at NASA-Lewis Research Center. Ten different plate sets were experimentally spin tested and the resulting data was analyzed. The first-four plate sets investigated tailoring patch locations and definitions to damp specific modes on spinning flat graphite/epoxy plates as a function of rotational speed. The remaining six plate sets investigated damping patch size and location on specific modes of pretwisted (30 degrees) graphite/epoxy plates. The results reveal that: (1) significant amount of damping can be added using a small amount of damping material, (2) the damped plates experienced no failures up to the tested 28,000 g's and 750,000 cycles, (3) centrifugal loads caused an increase in bending frequencies and corresponding reductions in bending damping levels that are proportional to the bending stiffness increase, and (4) the centrifugal loads caused a decrease in torsion natural frequency and increase in damping levels of pretwisted composite plates.

  9. Investigation of the unidirectional spin heat conveyer effect in a 200 nm thin Yttrium Iron Garnet film

    NASA Astrophysics Data System (ADS)

    Wid, Olga; Bauer, Jan; Müller, Alexander; Breitenstein, Otwin; Parkin, Stuart S. P.; Schmidt, Georg

    2016-06-01

    We have investigated the unidirectional spin wave heat conveyer effect in sub-micron thick yttrium iron garnet (YIG) films using lock-in thermography (LIT). Although the effect is small in thin layers this technique allows us to observe asymmetric heat transport by magnons which leads to asymmetric temperature profiles differing by several mK on both sides of the exciting antenna, respectively. Comparison of Damon-Eshbach and backward volume modes shows that the unidirectional heat flow is indeed due to non-reciprocal spin-waves. Because of the finite linewidth, small asymmetries can still be observed when only the uniform mode of ferromagnetic resonance is excited. The latter is of extreme importance for example when measuring the inverse spin-Hall effect because the temperature differences can result in thermovoltages at the contacts. Because of the non-reciprocity these thermovoltages reverse their sign with a reversal of the magnetic field which is typically deemed the signature of the inverse spin-Hall voltage.

  10. High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes.

    PubMed

    Walk, Elyse L; McLaughlin, Sarah L; Weed, Scott A

    2015-07-25

    High-frequency ultrasound (HFUS) is widely employed as a non-invasive method for imaging internal anatomic structures in experimental small animal systems. HFUS has the ability to detect structures as small as 30 µm, a property that has been utilized for visualizing superficial lymph nodes in rodents in brightness (B)-mode. Combining power Doppler with B-mode imaging allows for measuring circulatory blood flow within lymph nodes and other organs. While HFUS has been utilized for lymph node imaging in a number of mouse  model systems, a detailed protocol describing HFUS imaging and characterization of the cervical lymph nodes in mice has not been reported. Here, we show that HFUS can be adapted to detect and characterize cervical lymph nodes in mice. Combined B-mode and power Doppler imaging can be used to detect increases in blood flow in immunologically-enlarged cervical nodes. We also describe the use of B-mode imaging to conduct fine needle biopsies of cervical lymph nodes to retrieve lymph tissue for histological  analysis. Finally, software-aided steps are described to calculate changes in lymph node volume and to visualize changes in lymph node morphology following image reconstruction. The ability to visually monitor changes in cervical lymph node biology over time provides a simple and powerful technique for the non-invasive monitoring of cervical lymph node alterations in preclinical mouse models of oral cavity disease.

  11. Variability of Tidal Volume in Patient-Triggered Mechanical Ventilation in ARDS.

    PubMed

    Perinel-Ragey, Sophie; Baboi, Loredana; Guérin, Claude

    2017-11-01

    Limiting tidal volume (V T ) in patients with ARDS may not be achieved once patient-triggered breaths occur. Furthermore, ICU ventilators offer numerous patient-triggered modes that work differently across brands. We systematically investigated, using a bench model, the effect of patient-triggered modes on the size and variability of V T at different breathing frequencies (f), patient effort, and ARDS severity. We used a V500 Infinity ICU ventilator connected to an ASL 5000 lung model whose compliance was mimicking mild, moderate, and severe ARDS. Thirteen patient-triggered modes were tested, falling into 3 categories, namely volume control ventilation with mandatory minute ventilation; pressure control ventilation, including airway pressure release ventilation (APRV); and pressure support ventilation. Two levels of f and effort were tested for each ARDS severity in each mode. Median (first-third quartiles) V T was compared across modes using non-parametric tests. The probability of V T > 6 mL/kg ideal body weight was assessed by binomial regression and expressed as the odds ratio (OR) with 95% CI. V T variability was measured from the coefficient of variation. V T distribution over all f, effort, and ARDS categories significantly differed across modes ( P < .001, Kruskal-Wallis test). V T was significantly greater with pressure support (OR 420 mL, 95% CI 332-527 mL) than with any other mode except for variable pressure support level. Risk for V T to be > 6 mL/kg was significantly increased with spontaneous breaths patient-triggered by pressure support (OR 19.36, 95% CI 12.37-30.65) and significantly reduced in APRV (OR 0.44, 95% CI 0.26-0.72) and pressure support with guaranteed volume mode. The risk increased with increasing effort and decreasing f. Coefficient of variation of V T was greater for low f and volume control-mandatory minute ventilation and pressure control modes. APRV had the greatest within-mode variability. Risk of V T > 6 mL/kg was significantly reduced in APRV and pressure support with guaranteed volume mode. APRV had the highest variability. Pressure support with guaranteed volume could be tested in patients with ARDS. Copyright © 2017 by Daedalus Enterprises.

  12. Equation of State for Solid Phase I of Carbon Dioxide Valid for Temperatures up to 800 K and Pressures up to 12 GPa

    NASA Astrophysics Data System (ADS)

    Martin Trusler, J. P.

    2011-12-01

    The available thermodynamic-property data for solid phase I of carbon dioxide ("dry ice") are reviewed and used to determine the parameters of a new fundamental equation of state constructed in the form of a Helmholtz energy function with temperature and molar volume as the independent variables. The experimental data considered include the pressure, molar volume, and isobaric heat capacity along the sublimation curve, the melting-pressure curve, and molar volume in the compressed solid at temperatures from 295 to 764 K and pressures up to 12 GPa. The equation of state is based on the quasi-harmonic approximation, incorporating a Debye oscillator distribution for the vibrons, two discrete modes for the librons and a further three distinct modes for the internal vibrations of the CO2 molecule. A small anharmonic correction term is included, which is significant mainly in the region of the triple point. The estimated relative uncertainty of molar volume at specified temperature and pressure calculated from the equation of state is 0.02% on the sublimation curve and 1.5% in the compressed solid; for isobaric heat capacity on the sublimation curve, the uncertainty varies from 5.0% to 0.5% between 2 and 195 K. Auxiliary equations for the pressure and molar volume on the sublimation and melting curves are given. The equation of state is valid at temperatures from 0 to 800 K and at pressures from the solid-fluid phase boundary to 12 GPa.

  13. Proceedings of the 2010 Antenna Applications Symposium Held in Monticello, Illinois on 21-23 September 2010. Volume 2

    DTIC Science & Technology

    2010-12-01

    papers relating to antenna arrays and elements, millimeter wave antennas, simulation and measurement of antennas, integrated antennas, and antenna...Hansen 282 v Artificial Impedance Surface Antenna Design and Simulation D.J. Gregoire and J.S. Colburn 288 uCAST - A New Generation UTD...radiating mode to be self-resonant in the electrically small region. 260 hs (cm) Predicted L0 (nH) Simulated L0 (nH) R1 (Ω) Q1 -- -- -- 7.5

  14. Defense Small Business Innovation Research Program (SBIR). Volume 1. Army Abstracts of Phase 1 Awards 1991

    DTIC Science & Technology

    1991-01-01

    Office: MICOM HUNTSVILLE, AL 35805 Contract #: DAAHO1-92-C-R150 Phone: (205) 876-7502 Pi: D. BRETI BEASLEY Title: INFRARED LASER DIODE BASED INFRARED ...TECHNIQUES WILL BE INVESTIGATED TO DESIGN A FORM FIT GIMBALL-MOUNTED 94 GHZ/ INFRARED FOCAL PLANE ARRAY DUAL-MODE MISSILE SEEKER SENSOR BASED ON LOW...RESOLUTION AT 94 GHZ AND A 128X128 ARRAY IR IMAGE PROCESSING FOR AUTONOMOUS TARGET RECOGNITION AND AIMPOINT SELECTION. THE 94 GHZ AND INFRARED ELECTRONICS

  15. AUTOMATED CELL SEGMENTATION WITH 3D FLUORESCENCE MICROSCOPY IMAGES.

    PubMed

    Kong, Jun; Wang, Fusheng; Teodoro, George; Liang, Yanhui; Zhu, Yangyang; Tucker-Burden, Carol; Brat, Daniel J

    2015-04-01

    A large number of cell-oriented cancer investigations require an effective and reliable cell segmentation method on three dimensional (3D) fluorescence microscopic images for quantitative analysis of cell biological properties. In this paper, we present a fully automated cell segmentation method that can detect cells from 3D fluorescence microscopic images. Enlightened by fluorescence imaging techniques, we regulated the image gradient field by gradient vector flow (GVF) with interpolated and smoothed data volume, and grouped voxels based on gradient modes identified by tracking GVF field. Adaptive thresholding was then applied to voxels associated with the same gradient mode where voxel intensities were enhanced by a multiscale cell filter. We applied the method to a large volume of 3D fluorescence imaging data of human brain tumor cells with (1) small cell false detection and missing rates for individual cells; and (2) trivial over and under segmentation incidences for clustered cells. Additionally, the concordance of cell morphometry structure between automated and manual segmentation was encouraging. These results suggest a promising 3D cell segmentation method applicable to cancer studies.

  16. Characterization of Large Volume CLYC Scintillators for Nuclear Security Applications

    NASA Astrophysics Data System (ADS)

    Soundara-Pandian, Lakshmi; Tower, J.; Hines, C.; O'Dougherty, P.; Glodo, J.; Shah, K.

    2017-07-01

    We report on our development of large volume Cs2LiYCl6 (CLYC) detectors for nuclear security applications. Three-inch diameter boules have been grown and 3-in right cylinders have been fabricated. Crystals containing either >95% 6Li or >99% 7Li have been grown for applications specific to thermal or fast neutron detection, respectively. We evaluated their gamma and neutron detection properties and the performance is as good as small size crystals. Gamma and neutron efficiencies were measured for large crystals and compared with smaller size crystals. With their excellent performance characteristics, and the ability to detect fast neutrons, CLYC detectors are excellent triple-mode scintillators for use in handheld and backpack instruments for nuclear security applications.

  17. Cell population data in neonates: differences by age group and associations with perinatal factors.

    PubMed

    Lee, J; Kim, S Y; Lee, W; Han, K; Sung, I K

    2015-10-01

    Cell population data (CPD) describe physical parameters of white blood cell subpopulations and are reported to be of some value in the diagnosis of sepsis in neonates. Before using the CPD for diagnosing sepsis, the baseline features of the CPD distribution in healthy neonates should be clarified. The aim of this study was to compare the CPD distributions of healthy neonates and other age groups and to identify perinatal factors that are associated with changes in the CPD distribution of healthy neonates. The CPD distribution of 69 samples from term neonates was compared with adolescents and adults. The CPD distribution of 163 samples from healthy neonates was analyzed in association with perinatal factors, including gestational age, chronologic age, birthweight, delivery mode, premature rupture of membranes, diabetes, and pregnancy-induced hypertension. The CPD distribution for term neonates was significantly different from those in adolescents and adults. The mean lymphocyte volume showed a negative correlation with gestational age at birth (r = -0.305; P < 0.01). The mean neutrophil volume was smaller in the cesarean section group than in the normal delivery group. The small for gestational age (SGA) group had smaller mean neutrophil volume and mean monocyte volume than the appropriate for gestational age group. The CPD distribution of healthy neonates differed from those of adolescents or adults, and the differences were associated with gestational age, delivery mode, and being SGA. © 2015 John Wiley & Sons Ltd.

  18. Measurements of long-wavelength spin waves for the magnetic field in the Damon-Eshbach, backward-volume and forward-volume geometries of an yttrium iron garnet film

    DOE PAGES

    Bang, Wonbae; Lim, Jinho; Trossman, Jonathan; ...

    2018-03-23

    In this paper, we report systematic measurements of the dispersion of long wavelength spin waves for a wide range of wave vectors for the magnetic field along the three principal directions defining the forward volume, backward volume and Damon-Eshbach modes of a 9.72 μm thick film of an yttrium iron garnet obtained using lithographically patterned, multi-element, spatially resonant, antennas. Overall good agreement is found between the experimental data for the backward volume and Damon-Eshbach modes and the magnetostatic theory of Damon and Eshbach. Also, good agreement is found between the experimental data for the forward volume mode and the theorymore » of Damon and van de Vaart.« less

  19. Measurements of long-wavelength spin waves for the magnetic field in the Damon-Eshbach, backward-volume and forward-volume geometries of an yttrium iron garnet film

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bang, Wonbae; Lim, Jinho; Trossman, Jonathan

    In this paper, we report systematic measurements of the dispersion of long wavelength spin waves for a wide range of wave vectors for the magnetic field along the three principal directions defining the forward volume, backward volume and Damon-Eshbach modes of a 9.72 μm thick film of an yttrium iron garnet obtained using lithographically patterned, multi-element, spatially resonant, antennas. Overall good agreement is found between the experimental data for the backward volume and Damon-Eshbach modes and the magnetostatic theory of Damon and Eshbach. Also, good agreement is found between the experimental data for the forward volume mode and the theorymore » of Damon and van de Vaart.« less

  20. Effects of initial amplitude and pycnocline thickness on the evolution of mode-2 internal solitary waves

    NASA Astrophysics Data System (ADS)

    Cheng, Ming-Hung; Hsieh, Chih-Min; Hwang, Robert R.; Hsu, John R.-C.

    2018-04-01

    Numerical simulations are performed to investigate the effects of the initial amplitude and pycnocline thickness on the evolutions of convex mode-2 internal solitary waves propagating on the flat bottom. A finite volume method based on a Cartesian grid system is adopted to solve the Navier-Stokes equations using the improved delayed detached eddy simulation turbulent closure model. Mode-2 internal solitary waves (ISWs) are found to become stable at t = 15 s after lifting a vertical sluice gate by a gravity collapse mechanism. Numerical results from three cases of pycnocline thickness reveal the following: (1) the occurrence of a smooth mode-2 ISW when the wave amplitude is small; (2) the PacMan phenomenon for large amplitude waves; and (3) pseudo vortex shedding in the case of very large amplitudes. In general, basic wave properties (wave amplitude, wave speed, vorticity, and wave energy) increase as the wave amplitude increases for a specific value of the pycnocline thickness. Moreover, the pycnocline thickness chiefly determines the core size of a convex mode-2 ISW, while the step depth (that generates an initial wave amplitude) and offset in pycnocline govern the waveform type during its propagation on the flat bottom.

  1. Laser optoacoustic tomography for medical diagnostics: principles

    NASA Astrophysics Data System (ADS)

    Oraevsky, Alexander A.; Esenaliev, Rinat O.; Jacques, Steven L.; Tittel, Frank K.

    1996-04-01

    This paper is to describe principles of laser optoacoustic tomography for medical diagnostics. Two types of imaging modes are presented. The first is the tomography in transmission mode, which utilizes detection of stress transients transmitted from the laser-excited volume toward the depth through thick layers of tissue. The second is the tomography in reflection mode which utilizes detection of stress transients generated in superficial tissue layer and reflected back toward tissue surface. To distinguish the two modes, we have abbreviated them as (1) laser optoacoustic tomography in transmission mode, LOATT, and (2) time-resolved stress detection tomography of light absorption, TRSDTLA, in reflection mode where emphasis is made on high spatial resolution of images. The basis for laser optoacoustic tomography is the time-resolved detection of laser-induced transient stress waves, selectively generated in absorbing tissues of diagnostic interest. Such a technique allows one to visualize absorbed light distribution in turbid biological tissues irradiated by short laser pulses. Laser optoacoustic tomography can be used for detection of tissue pathological changes that result in either increased concentration of various tissue chromophores such as hemoglobin or in development of enhanced microcirculation in diseased tissue. Potential areas of applications are diagnosis of cancer, brain hemorrhages, arterial atherosclerotic plaques, and other diseased tissues. In addition, it can provide feedback information during medical treatments. Both LOATT and TRSDTLA utilize laser excitation of biological tissues and sensitive detection of laser-induced stress waves. Optical selectivity is based upon differences in optical properties of pathologically different tissues. Sensitivity comes from stress generation under irradiation conditions of temporal stress confinement. The use of sensitive wide-band lithium niobate acoustic transducers expands limits of laser optoacoustic tomography. The technology allows us to determine directly temperature distributions in tissues and locate tissues volumes with different absorption. To demonstrate principles of TRSDTLA, experiments were conducted in vivo with mice-model for breast cancer using specially designed front-surface transducers- reflectometers. To present advantages and limitation of LOATT, experiments were performed in phantoms made of gel with polystyrene spheres colored with copper sulfate. Our experimental results and theoretical calculations show that TRSDTLA can be applied for non- invasive histology of layered tissues with in-depth resolution of up to 2 microns. TRSDTLA in acoustic reflection mode is promising for diagnostics of skin and ocular diseases. LOATT in acoustic transmission mode can be applied for detection of small tissue volumes with enhanced absorption located inside organs at the depth of up to 10 cm.

  2. Surface plasmon polariton nanocavity with ultrasmall mode volume

    NASA Astrophysics Data System (ADS)

    Yue, Wencheng; Yao, Peijun; Luo, Huiwen; Liu, Wen

    2017-08-01

    We present a plasmonic nanocavity structure, consisting of a gallium phosphide (GaP) cylinder penetrating into a rectangular silver plate, and study its properties using a finite element method (FEM). An ultrasmall mode volume of 1.5×10-5[λ_0/(2n)]3 is achieved, which is more than 200 times smaller than the previous ultrasmall mode volume plasmonic nanodisk resonators. Meanwhile, the quality factor of the plasmonic nanocavity is about 38.2 and is over two times greater than the ultrasmall mode volume plasmonic nanodisk resonators. Compared to the aforementioned plasmonic nanodisk resonators, a more than one-order of magnitude larger Purcell factor of 1.2×104 is achieved. We determined the resonant modes of our plasmonic nanocavity are dipolar plasmon modes by analyzing the electric field properties. In addition, we investigate the dependence of the optical properties on the refractive index of the cavity material and discuss the effect of including the silica (SiO2) substrate. Our work provides an alternative approach to achieve ultrasmall plasmonic nanocavity of interest in applications to many areas of research, including device physics, nonlinear optics and quantum optics.

  3. Effect of settling particles on the stability of a particle-laden flow in a vertical plane channel

    NASA Astrophysics Data System (ADS)

    Boronin, S. A.; Osiptsov, A. N.

    2018-03-01

    The stability of a viscous particle-laden flow in a vertical plane channel in the presence of the gravity force is studied. The flow is described using a two-fluid "dusty-gas" model with negligibly small volume fraction of fines and two-way coupling of the phases. Two different profiles of the particle number density in the main flow are considered: homogeneous and non-homogeneous in the form of two layers symmetric about the channel axis. The novel element of the linear-stability problem formulation is a particle velocity slip in the main flow caused by the gravity-induced settling of the dispersed phase. The eigenvalue problem for a linearized system of governing equations is solved using the orthonormalization and QZ algorithms. For a uniform particle number density distribution, it is found that there exists a domain in the plane of Froude and Stokes numbers, in which the two-phase flow in a vertical channel is stable for an arbitrary Reynolds number. This stability domain corresponds to relatively small-inertia particles and large velocity-slip in the main flow. In contrast to the flow with a uniform particle number density distribution, the stratified dusty-gas flow in a vertical channel is unstable over a wide range of governing parameters. The instability at small Reynolds numbers is determined by the gravitational mode characterized by small wavenumbers (long-wave instability), while at larger Reynolds numbers the instability is dominated by the shear mode with the time-amplification factor larger than that of the gravitational mode. The results of the study can be used for optimization of a large number of technological processes, including those in riser reactors, pneumatic conveying in pipeline systems, hydraulic fracturing, and well cementing.

  4. Development of a high-throughput microscale cell disruption platform for Pichia pastoris in rapid bioprocess design.

    PubMed

    Bláha, Benjamin A F; Morris, Stephen A; Ogonah, Olotu W; Maucourant, Sophie; Crescente, Vincenzo; Rosenberg, William; Mukhopadhyay, Tarit K

    2018-01-01

    The time and cost benefits of miniaturized fermentation platforms can only be gained by employing complementary techniques facilitating high-throughput at small sample volumes. Microbial cell disruption is a major bottleneck in experimental throughput and is often restricted to large processing volumes. Moreover, for rigid yeast species, such as Pichia pastoris, no effective high-throughput disruption methods exist. The development of an automated, miniaturized, high-throughput, noncontact, scalable platform based on adaptive focused acoustics (AFA) to disrupt P. pastoris and recover intracellular heterologous protein is described. Augmented modes of AFA were established by investigating vessel designs and a novel enzymatic pretreatment step. Three different modes of AFA were studied and compared to the performance high-pressure homogenization. For each of these modes of cell disruption, response models were developed to account for five different performance criteria. Using multiple responses not only demonstrated that different operating parameters are required for different response optima, with highest product purity requiring suboptimal values for other criteria, but also allowed for AFA-based methods to mimic large-scale homogenization processes. These results demonstrate that AFA-mediated cell disruption can be used for a wide range of applications including buffer development, strain selection, fermentation process development, and whole bioprocess integration. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 34:130-140, 2018. © 2017 American Institute of Chemical Engineers.

  5. Perturbative approach to covariance matrix of the matter power spectrum

    NASA Astrophysics Data System (ADS)

    Mohammed, Irshad; Seljak, Uroš; Vlah, Zvonimir

    2017-04-01

    We evaluate the covariance matrix of the matter power spectrum using perturbation theory up to dominant terms at 1-loop order and compare it to numerical simulations. We decompose the covariance matrix into the disconnected (Gaussian) part, trispectrum from the modes outside the survey (supersample variance) and trispectrum from the modes inside the survey, and show how the different components contribute to the overall covariance matrix. We find the agreement with the simulations is at a 10 per cent level up to k ˜ 1 h Mpc-1. We show that all the connected components are dominated by the large-scale modes (k < 0.1 h Mpc-1), regardless of the value of the wave vectors k, k΄ of the covariance matrix, suggesting that one must be careful in applying the jackknife or bootstrap methods to the covariance matrix. We perform an eigenmode decomposition of the connected part of the covariance matrix, showing that at higher k, it is dominated by a single eigenmode. The full covariance matrix can be approximated as the disconnected part only, with the connected part being treated as an external nuisance parameter with a known scale dependence, and a known prior on its variance for a given survey volume. Finally, we provide a prescription for how to evaluate the covariance matrix from small box simulations without the need to simulate large volumes.

  6. Room-temperature cavity quantum electrodynamics with strongly coupled Dicke states

    NASA Astrophysics Data System (ADS)

    Breeze, Jonathan D.; Salvadori, Enrico; Sathian, Juna; Alford, Neil McN.; Kay, Christopher W. M.

    2017-09-01

    The strong coupling regime is essential for efficient transfer of excitations between states in different quantum systems on timescales shorter than their lifetimes. The coupling of single spins to microwave photons is very weak but can be enhanced by increasing the local density of states by reducing the magnetic mode volume of the cavity. In practice, it is difficult to achieve both small cavity mode volume and low cavity decay rate, so superconducting metals are often employed at cryogenic temperatures. For an ensembles of N spins, the spin-photon coupling can be enhanced by √{N } through collective spin excitations known as Dicke states. For sufficiently large N the collective spin-photon coupling can exceed both the spin decoherence and cavity decay rates, making the strong-coupling regime accessible. Here we demonstrate strong coupling and cavity quantum electrodynamics in a solid-state system at room-temperature. We generate an inverted spin-ensemble with N 1015 by photo-exciting pentacene molecules into spin-triplet states with spin dephasing time T2* 3 μs. When coupled to a 1.45 GHz TE01δ mode supported by a high Purcell factor strontium titanate dielectric cavity (Vm 0.25 cm3, Q 8,500), we observe Rabi oscillations in the microwave emission from collective Dicke states and a 1.8 MHz normal-mode splitting of the resultant collective spin-photon polariton. We also observe a cavity protection effect at the onset of the strong-coupling regime which decreases the polariton decay rate as the collective coupling increases.

  7. Experimental Platform for Ultra-high Dose Rate FLASH Irradiation of Small Animals Using a Clinical Linear Accelerator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schüler, Emil; Trovati, Stefania; King, Gregory

    Purpose: A key factor limiting the effectiveness of radiation therapy is normal tissue toxicity, and recent preclinical data have shown that ultra-high dose rate irradiation (>50 Gy/s, “FLASH”) potentially mitigates this effect. However, research in this field has been strongly limited by the availability of FLASH irradiators suitable for small animal experiments. We present a simple methodologic approach for FLASH electron small animal irradiation with a clinically available linear accelerator (LINAC). Methods and Materials: We investigated the FLASH irradiation potential of a Varian Clinac 21EX in both clinical mode and after tuning of the LINAC. We performed detailed FLUKA Monte Carlomore » and experimental dosimetric characterization at multiple experimental locations within the LINAC head. Results: Average dose rates of ≤74 Gy/s were achieved in clinical mode, and the dose rate after tuning exceeded 900 Gy/s. We obtained 220 Gy/s at 1-cm depth for a >4-cm field size with 90% homogeneity throughout a 2-cm-thick volume. Conclusions: We present an approach for using a clinical LINAC for FLASH irradiation. We obtained dose rates exceeding 200 Gy/s after simple tuning of the LINAC, with excellent dosimetric properties for small animal experiments. This will allow for increased availability of FLASH irradiation to the general research community.« less

  8. Flatland Photonics: Circumventing Diffraction with Planar Plasmonic Architectures

    NASA Astrophysics Data System (ADS)

    Dionne, Jennifer Anne

    On subwavelength scales, photon-matter interactions are limited by diffraction. The diffraction limit restricts the size of optical devices and the resolution of conventional microscopes to wavelength-scale dimensions, severely hampering our ability to control and probe subwavelength-scale optical phenomena. Circumventing diffraction is now a principle focus of integrated nanophotonics. Surface plasmons provide a particularly promising approach to sub-diffraction-limited photonics. Surface plasmons are hybrid electron-photon modes confined to the interface between conductors and transparent materials. Combining the high localization of electronic waves with the propagation properties of optical waves, plasmons can achieve extremely small mode wavelengths and large local electromagnetic field intensities. Through their unique dispersion, surface plasmons provide access to an enormous phase space of refractive indices and propagation constants that can be readily tuned with material or geometry. In this thesis, we explore both the theory and applications of dispersion in planar plasmonic architectures. Particular attention is given to the modes of metallic core and plasmon slot waveguides, which can span positive, near-zero, and even negative indices. We demonstrate how such basic plasmonic geometries can be used to develop a suite of passive and active plasmonic components, including subwavelength waveguides, color filters, negative index metamaterials, and optical MOS field effect modulators. Positive index modes are probed by near- and far-field techniques, revealing plasmon wavelengths as small as one-tenth of the excitation wavelength. Negative index modes are characterized through direct visualization of negative refraction. By fabricating prisms comprised of gold, silicon nitride, and silver multilayers, we achieve the first experimental demonstration of a negative index material at visible frequencies, with potential applications for sub-diffraction-limited microscopy and electromagnetic cloaking. We exploit this tunability of complex plasmon mode indices to create a compact metal-oxide-Si (MOS) field effect plasmonic modulator (or plasMOStor). By transforming the MOS gate oxide into an optical channel, amplitude modulation depths of 11.2 dB are achieved in device volumes as small as one one-fifth of a cubic wavelength. Our results indicate the accessibility of tunable refractive indices over a wide frequency band, facilitating design of a new materials class with extraordinary optical properties and applications.

  9. Surface plasmon polariton laser based on a metallic trench Fabry-Perot resonator

    PubMed Central

    Zhu, Wenqi; Xu, Ting; Wang, Haozhu; Zhang, Cheng; Deotare, Parag B.; Agrawal, Amit; Lezec, Henri J.

    2017-01-01

    Recent years have witnessed a growing interest in the development of small-footprint lasers for potential applications in small-volume sensing and on-chip optical communications. Surface plasmons—electromagnetic modes evanescently confined to metal-dielectric interfaces—offer an effective route to achieving lasing at nanometer-scale dimensions when resonantly amplified in contact with a gain medium. We achieve narrow-linewidth visible-frequency lasing at room temperature by leveraging surface plasmons propagating in an open Fabry-Perot cavity formed by a flat metal surface coated with a subwavelength-thick layer of optically pumped gain medium and orthogonally bound by a pair of flat metal sidewalls. We show how the lasing threshold and linewidth can be lowered by incorporating a low-profile tapered grating on the cavity floor to couple the excitation beam into a pump surface plasmon polariton providing a strong modal overlap with the gain medium. Low-perturbation transmission-configuration sampling of the lasing plasmon mode is achieved via an evanescently coupled recessed nanoslit, opening the way to high–figure of merit refractive index sensing of analytes interacting with the open metallic trench. PMID:28989962

  10. Improved Characteristics of Laser Source of Ions Using a Frequency Mode Laser

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khaydarov, R. T.

    2008-04-07

    We used a mass-spectrometric method to investigate the characteristics of laser-produced plasma ions depending on the nature of the target and on the parameters of the laser radiation. Experiments are carried out on porous Y{sub 2}O{sub 3} targets with different densities {rho}, subjected to a laser radiation, where the laser works in a frequency mode (v = l-12 Hz). We found that the laser frequency has a significant effect on the parameters of plasma ions: with increasing the frequency of the laser the charge, energy and intensity of ions increase for a given parameters of the target. This effect ismore » more pronounced for small densities of the target. We related these two effects to a non-linear ionization process in the plasma due to the formation of dense plasma volume inside the sample absorbing the laser radiation and to the change of the focusing conditions in the case of the frequency mode laser.« less

  11. Ultra-high-Q three-dimensional photonic crystal nano-resonators.

    PubMed

    Tang, Lingling; Yoshie, Tomoyuki

    2007-12-10

    Two nano-resonator modes are designed in a woodpile three-dimensional photonic crystal by the modulation of unit cell size along a low-loss optical waveguide. One is a dipole mode with 2.88 cubic half-wavelengths mode volume. The other is a quadrupole mode with 8.3 cubic half-wavelengths mode volume. Light is three-dimensionally confined by a complete photonic band gap so that, in the analyzed range, the quality factor exponentially increases as the increase in the number of unit cells used for confinement of light.

  12. Static SPME sampling of VOCs emitted from indoor building materials: prediction of calibration curves of single compounds for two different emission cells.

    PubMed

    Mocho, Pierre; Desauziers, Valérie

    2011-05-01

    Solid-phase microextraction (SPME) is a powerful technique, easy to implement for on-site static sampling of indoor VOCs emitted by building materials. However, a major constraint lies in the establishment of calibration curves which requires complex generation of standard atmospheres. Thus, the purpose of this paper is to propose a model to predict adsorption kinetics (i.e., calibration curves) of four model VOCs. The model is based on Fick's laws for the gas phase and on the equilibrium or the solid diffusion model for the adsorptive phase. Two samplers (the FLEC® and a home-made cylindrical emission cell), coupled to SPME for static sampling of material emissions, were studied. A good agreement between modeling and experimental data is observed and results show the influence of sampling rate on mass transfer mode in function of sample volume. The equilibrium model is adapted to quite large volume sampler (cylindrical cell) while the solid diffusion model is dedicated to small volume sampler (FLEC®). The limiting steps of mass transfer are the diffusion in gas phase for the cylindrical cell and the pore surface diffusion for the FLEC®. In the future, this modeling approach could be a useful tool for time-saving development of SPME to study building material emission in static mode sampling.

  13. Topical Meeting on Laser and Optical Remote Sensing: Instrumentation and Techniques Technical Digest Held in North Falmoth, Massachusetts on September 28-October 1, 1987. Volume 18.

    DTIC Science & Technology

    1988-08-01

    LWIR ) to be used. Because the "water-leaving" detectors. To make the footprint projection radiance is small, all six of the visible and of these...photovoltaic mode. TDI is allows viewing of an internal blackbody for performed off-focal-plane after DC-restore of the LWIR channels. A space digitization...scanning mercury cadmium telluride (PC: HgCdTe) telescope are provided for calibration. DC- detectors are used for the LWIR bands. restore is performed once

  14. Hybrid photonic-plasmonic crystal nanocavity sensors

    NASA Astrophysics Data System (ADS)

    Cheng, Pi-Ju; Chiang, Chih-Kai; Chou, Bo-Tsun; Huang, Zhen-Ting; Ku, Yun-Cheng; Kuo, Mao-Kuen; Hsu, Jin-Chen; Lin, Tzy-Rong

    2018-02-01

    We have investigated a hybrid photonic-plasmonic crystal nanocavity consisting of a silicon grating nanowire adjacent to a metal surface with a gain gap between them. The hybrid plasmonic cavity modes are highly confined in the gap due to the strong coupling of the photonic crystal cavity modes and the surface plasmonic gap modes. Using finite-element method (FEM), guided modes of the hybrid plasmonic waveguide (WG) were numerically determined at a wavelength of 1550 nm. The modal characteristics such as WG confinement factors and modal losses of the fundamental hybrid plasmonic modes were obtained as a function of groove depth at various gap heights. Furthermore, the band structure of the hybrid crystal modes corresponding to a wide band gap of 17.8 THz is revealed. To enclose the optical energy effectively, a single defect was introduced into the hybrid crystal. At a deep subwavelength defect length as small as 270 nm, the resonant mode exhibits a high quality factor of 567 and an ultrasmall mode volume of 1.9 × 10- 3 ( λ/ n eff)3 at the resonance wavelength of 1550 nm. Compared to conventional photonic crystal nanowire cavities in the absence of a metal surface, the factor Q/ V m is significantly enhanced by about 15 times. The designed hybrid photonic-plasmonic cavity sensors exhibit distinguished characteristics such as sensitivity of 443 nm/RIU and figure of merit of 129. The proposed nanocavities open new possibilities for various applications with strong light-matter interaction, such as biosensors and nanolasers.

  15. A phylogenetic analysis of egg size, clutch size, spawning mode, adult body size, and latitude in reef fishes

    NASA Astrophysics Data System (ADS)

    Kasimatis, Katja; Riginos, Cynthia

    2016-06-01

    Theoretical treatments of egg size in fishes suggest that constraints on reproductive output should create trade-offs between the size and number of eggs produced per spawn. For marine reef fishes, the observation of distinct reproductive care strategies (demersal guarding, egg scattering, and pelagic spawning) has additionally prompted speculation that these strategies reflect alternative fitness optima with selection on egg size differing by reproductive mode and perhaps latitude. Here, we aggregate data from 278 reef fish species and test whether clutch size, reproductive care, adult body size, and latitudinal bands (i.e., tropical, subtropical, and temperate) predict egg size, using a statistically unified framework that accounts for phylogenetic correlations among traits. We find no inverse relationship between species egg size and clutch size, but rather that egg size differs by reproductive mode (mean volume for demersal eggs = 1.22 mm3, scattered eggs = 0.18 mm3, pelagic eggs = 0.52 mm3) and that clutch size is strongly correlated with adult body size. Larger eggs were found in temperate species compared with tropical species in both demersal guarders and pelagic spawners, but this difference was not strong when accounting for phylogenetic correlations, suggesting that differences in species composition underlies regional differences in egg size. In summary, demersal guarders are generally small fishes with small clutch sizes that produce large eggs. Pelagic spawners and egg scatterers are variable in adult and clutch size. Although pelagic spawned eggs are variable in size, those of scatterers are consistently small.

  16. Acoustic levitation in the presence of gravity

    NASA Technical Reports Server (NTRS)

    Collas, P.; Barmatz, M.; Shipley, C.

    1989-01-01

    The method of Gor'kov (1961) has been applied to derive general expressions for the total potential and force on a small spherical object in a resonant chamber in the presence of both acoustic and gravitational force fields. The levitation position is also determined in rectangular resonators for the simultaneous excitation of up to three acoustic modes, and the results are applied to the triple-axis acoustic levitator. The analysis is applied to rectangular, spherical, and cylindrical single-mode levitators that are arbitrarily oriented relative to the gravitational force field. Criteria are determined for isotropic force fields in rectangular and cylindrical resonators. It is demonstrated that an object will be situated within a volume of possible levitation positions at a point determined by the relative strength of the acoustic and gravitational fields and the orientation of the chamber relative to gravity.

  17. Carbon dioxide clearance in rabbits during expiratory phase intratracheal pulmonary ventilation.

    PubMed

    Meyappan, Raju T; Raszynski, Andre; Bohorquez, Jorge; Totapally, Balagangadhar R; Koul, Pulin B; Norozian, Faraz M; Valcourt, Karl; Torbati, Dan

    2007-01-01

    The purpose of this study was to compare the efficacy of CO2 removal during conventional mechanical ventilation (CMV) with and without expiratory phase intratracheal pulmonary ventilation (expiratory ITPV or Exp-ITPV); and to compare CO2 clearance during Exp-ITPV, in pressure-controlled ventilation (PCV) and in volume-controlled ventilation (VCV) modes. Seven anesthetized rabbits were tracheotomized and intubated using a 4 mm endotracheal tube. Venous and arterial lines were established. The rabbits were paralyzed, mechanically ventilated, and ventilation parameters were adjusted to achieve baseline arterial hypercapnia. Animals were then ventilated during 30-minute trials of CMV and Exp-ITPV, in both PCV and VCV modes. A custom-built, microprocessor-controlled solenoid valve was used to limit ITPV gas flow to the expiratory phase. Proximal and carinal airway pressures and hemodynamic variables were continuously recorded, and arterial blood gases were analyzed at the end of each trial. Exp-ITPV, as compared with CMV, reduced arterial PCO2 by 12% and 21% in PCV and VCV modes, respectively (p < 0.02 and p < 0.001; one-sided paired t test), without significant changes in other cardiorespiratory variables. In conclusion, Exp-ITPV is more effective than CMV in clearing CO2 through a small endotracheal tube. Exp-ITPV is also more effective in VCV mode than PCV mode.

  18. Derivation of a respiration trigger signal in small animal list-mode PET based on respiration-induced variations of the ECG signal.

    PubMed

    Todica, Andrei; Lehner, Sebastian; Wang, Hao; Zacherl, Mathias J; Nekolla, Katharina; Mille, Erik; Xiong, Guoming; Bartenstein, Peter; la Fougère, Christian; Hacker, Marcus; Böning, Guido

    2016-02-01

    Raw PET list-mode data contains motion artifacts causing image blurring and decreased spatial resolution. Unless corrected, this leads to underestimation of the tracer uptake and overestimation of the lesion size, as well as inaccuracies with regard to left ventricular volume and ejection fraction (LVEF), especially in small animal imaging. A respiratory trigger signal from respiration-induced variations in the electro-cardiogram (ECG) was detected. Original and revised list-mode PET data were used for calculation of left ventricular function parameters using both respiratory gating techniques. For adequately triggered datasets we saw no difference in mean respiratory cycle period between the reference standard (RRS) and the ECG-based (ERS) methods (1120 ± 159 ms vs 1120 ± 159 ms; P = n.s.). While the ECG-based method showed somewhat higher signal noise (66 ± 22 ms vs 51 ± 29 ms; P < .001), both respiratory triggering techniques yielded similar estimates for EDV, ESV, LVEF (RRS: 387 ± 56 µL, 162 ± 34 µL, 59 ± 5%; ERS: 389 ± 59 µL, 163 ± 35 µL, 59 ± 4%; P = n.s.). This study showed that respiratory gating signals can be accurately derived from cardiac trigger information alone, without the additional requirement for dedicated measurement of the respiratory motion in rats.

  19. On Stability of Plane and Cylindrical Poiseuille Flows of Nanofluids

    NASA Astrophysics Data System (ADS)

    Rudyak, V. Ya.; Bord, E. G.

    2017-11-01

    Stability of plane and cylindrical Poiseuille flows of nanofluids to comparatively small perturbations is studied. Ethylene glycol-based nanofluids with silicon dioxide particles are considered. The volume fraction of nanoparticles is varied from 0 to 10%, and the particle size is varied from 10 to 210 nm. Neutral stability curves are constructed, and the most unstable modes of disturbances are found. It is demonstrated that nanofluids are less stable than base fluids; the presence of particles leads to additional destabilization of the flow. The greater the volume fraction of nanoparticles and the smaller the particle size, the greater the degree of this additional destabilization. In this case, the critical Reynolds number significantly decreases, and the spectrum of unstable disturbances becomes different; in particular, even for the volume fraction of particles equal to 5%, the wave length of the most unstable disturbances of the nanofluid with particles approximately 20 nm in size decreases almost by a factor of 4.

  20. Optics-Integrated Microfluidic Platforms for Biomolecular Analyses

    PubMed Central

    Bates, Kathleen E.; Lu, Hang

    2016-01-01

    Compared with conventional optical methods, optics implemented on microfluidic chips provide small, and often much cheaper ways to interrogate biological systems from the level of single molecules up to small model organisms. The optical probing of single molecules has been used to investigate the mechanical properties of individual biological molecules; however, multiplexing of these measurements through microfluidics and nanofluidics confers many analytical advantages. Optics-integrated microfluidic systems can significantly simplify sample processing and allow a more user-friendly experience; alignments of on-chip optical components are predetermined during fabrication and many purely optical techniques are passively controlled. Furthermore, sample loss from complicated preparation and fluid transfer steps can be virtually eliminated, a particularly important attribute for biological molecules at very low concentrations. Excellent fluid handling and high surface area/volume ratios also contribute to faster detection times for low abundance molecules in small sample volumes. Although integration of optical systems with classical microfluidic analysis techniques has been limited, microfluidics offers a ready platform for interrogation of biophysical properties. By exploiting the ease with which fluids and particles can be precisely and dynamically controlled in microfluidic devices, optical sensors capable of unique imaging modes, single molecule manipulation, and detection of minute changes in concentration of an analyte are possible. PMID:27119629

  1. Heterogeneous Silicon III-V Mode-Locked Lasers

    NASA Astrophysics Data System (ADS)

    Davenport, Michael Loehrlein

    Mode-locked lasers are useful for a variety of applications, such as sensing, telecommunication, and surgical instruments. This work focuses on integrated-circuit mode-locked lasers: those that combine multiple optical and electronic functions and are manufactured together on a single chip. While this allows production at high volume and lower cost, the true potential of integration is to open applications for mode-locked laser diodes where solid state lasers cannot fit, either due to size and power consumption constraints, or where small optical or electrical paths are needed for high bandwidth. Unfortunately, most high power and highly stable mode-locked laser diode demonstrations in scientific literature are based on the Fabry-Perot resonator design, with cleaved mirrors, and are unsuitable for use in integrated circuits because of the difficulty of producing integrated Fabry-Perot cavities. We use silicon photonics and heterogeneous integration with III-V gain material to produce the most powerful and lowest noise fully integrated mode-locked laser diode in the 20 GHz frequency range. If low noise and high peak power are required, it is arguably the best performing fully integrated mode-locked laser ever demonstrated. We present the design methodology and experimental pathway to realize a fully integrated mode-locked laser diode. The construction of the device, beginning with the selection of an integration platform, and proceeding through the fabrication process to final optimization, is presented in detail. The dependence of mode-locked laser performance on a wide variety of design parameters is presented. Applications for integrated circuit mode-locked lasers are also discussed, as well as proposed methods for using integration to improve mode-locking performance to beyond the current state of the art.

  2. SANSMIC Validation.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weber, Paula D.; Rudeen, David Keith; Lord, David L.

    2014-08-01

    SANSMIC is solution mining software that was developed and utilized by SNL in its role as geotechnical advisor to the US DOE SPR for planning purposes. Three SANSMIC leach modes - withdrawal, direct, and reverse leach - have been revalidated with multiple test cases for each mode. The withdrawal mode was validated using high quality data from recent leach activity while the direct and reverse modes utilized data from historical cavern completion reports. Withdrawal results compared very well with observed data, including the location and size of shelves due to string breaks with relative leached volume differences ranging from 6more » - 10% and relative radius differences from 1.5 - 3%. Profile comparisons for the direct mode were very good with relative leached volume differences ranging from 6 - 12% and relative radius differences from 5 - 7%. First, second, and third reverse configurations were simulated in order to validate SANSMIC over a range of relative hanging string and OBI locations. The first-reverse was simulated reasonably well with relative leached volume differences ranging from 1 - 9% and relative radius differences from 5 - 12%. The second-reverse mode showed the largest discrepancies in leach profile. Leached volume differences ranged from 8 - 12% and relative radius differences from 1 - 10%. In the third-reverse, relative leached volume differences ranged from 10 - 13% and relative radius differences were %7E4 %. Comparisons to historical reports were quite good, indicating that SANSMIC is essentially the same as documented and validated in the early 1980's.« less

  3. Perturbative approach to covariance matrix of the matter power spectrum

    DOE PAGES

    Mohammed, Irshad; Seljak, Uros; Vlah, Zvonimir

    2016-12-14

    Here, we evaluate the covariance matrix of the matter power spectrum using perturbation theory up to dominant terms at 1-loop order and compare it to numerical simulations. We decompose the covariance matrix into the disconnected (Gaussian) part, trispectrum from the modes outside the survey (beat coupling or super-sample variance), and trispectrum from the modes inside the survey, and show how the different components contribute to the overall covariance matrix. We find the agreement with the simulations is at a 10\\% level up tomore » $$k \\sim 1 h {\\rm Mpc^{-1}}$$. We also show that all the connected components are dominated by the large-scale modes ($$k<0.1 h {\\rm Mpc^{-1}}$$), regardless of the value of the wavevectors $$k,\\, k'$$ of the covariance matrix, suggesting that one must be careful in applying the jackknife or bootstrap methods to the covariance matrix. We perform an eigenmode decomposition of the connected part of the covariance matrix, showing that at higher $k$ it is dominated by a single eigenmode. Furthermore, the full covariance matrix can be approximated as the disconnected part only, with the connected part being treated as an external nuisance parameter with a known scale dependence, and a known prior on its variance for a given survey volume. Finally, we provide a prescription for how to evaluate the covariance matrix from small box simulations without the need to simulate large volumes.« less

  4. 75 FR 29605 - Clean Alternative Fuel Vehicle and Engine Conversions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... Small Volume Manufacturers and Small Volume Test Groups 1. Definition of Small Volume Manufacturers, Small Volume Test Groups, and Small Volume Engine Families a. Light-Duty and Heavy-Duty Complete... and Engines 2. Test Groups, Engine Families, and Evaporative Families a. Test Groups for Light-Duty...

  5. The Aerosol Coarse Mode Initiative

    NASA Astrophysics Data System (ADS)

    Arnott, W. P.; Adhikari, N.; Air, D.; Kassianov, E.; Barnard, J.

    2014-12-01

    Many areas of the world show an aerosol volume distribution with a significant coarse mode and sometimes a dominant coarse mode. The large coarse mode is usually due to dust, but sea salt aerosol can also play an important role. However, in many field campaigns, the coarse mode tends to be ignored, because it is difficult to measure. This lack of measurements leads directly to a concomitant "lack of analysis" of this mode. Because, coarse mode aerosols can have significant effects on radiative forcing, both in the shortwave and longwave spectrum, the coarse mode -- and these forcings -- should be accounted for in atmospheric models. Forcings based only on fine mode aerosols have the potential to be misleading. In this paper we describe examples of large coarse modes that occur in areas of large aerosol loading (Mexico City, Barnard et al., 2010) as well as small loadings (Sacramento, CA; Kassianov et al., 2012; and Reno, NV). We then demonstrate that: (1) the coarse mode can contribute significantly to radiative forcing, relative to the fine mode, and (2) neglecting the coarse mode may result in poor comparisons between measurements and models. Next we describe -- in general terms -- the limitations of instrumentation to measure the coarse mode. Finally, we suggest a new initiative aimed at examining coarse mode aerosol generation mechanisms; transport and deposition; chemical composition; visible and thermal IR refractive indices; morphology; microphysical behavior when deposited on snow and ice; and specific instrumentation needs. Barnard, J. C., J. D. Fast, G. Paredes-Miranda, W. P. Arnott, and A. Laskin, 2010: Technical Note: Evaluation of the WRF-Chem "Aerosol Chemical to Aerosol Optical Properties" Module using data from the MILAGRO campaign, Atmospheric Chemistry and Physics, 10, 7325-7340. Kassianov, E. I., M. S. Pekour, and J. C. Barnard, 2012: Aerosols in Central California: Unexpectedly large contribution of coarse mode to aerosol radiative forcing, Geophys. Res. Lett., 39, L20806, doi:10.1029/2012GL053469.

  6. Abelian Higgs cosmic strings: Small-scale structure and loops

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hindmarsh, Mark; Stuckey, Stephanie; Bevis, Neil

    2009-06-15

    Classical lattice simulations of the Abelian Higgs model are used to investigate small-scale structure and loop distributions in cosmic string networks. Use of the field theory ensures that the small-scale physics is captured correctly. The results confirm analytic predictions of Polchinski and Rocha 29 for the two-point correlation function of the string tangent vector, with a power law from length scales of order the string core width up to horizon scale. An analysis of the size distribution of string loops gives a very low number density, of order 1 per horizon volume, in contrast with Nambu-Goto simulations. Further, our loopmore » distribution function does not support the detailed analytic predictions for loop production derived by Dubath et al. 30. Better agreement to our data is found with a model based on loop fragmentation 32, coupled with a constant rate of energy loss into massive radiation. Our results show a strong energy-loss mechanism, which allows the string network to scale without gravitational radiation, but which is not due to the production of string width loops. From evidence of small-scale structure we argue a partial explanation for the scale separation problem of how energy in the very low frequency modes of the string network is transformed into the very high frequency modes of gauge and Higgs radiation. We propose a picture of string network evolution, which reconciles the apparent differences between Nambu-Goto and field theory simulations.« less

  7. 40 CFR Appendix 7 to Subpart A of... - Determination of the Amount of Non-Aqueous Drilling Fluid (NAF) Base Fluid From Drill Cuttings by...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... multiplying the density of the small volume NAF-cuttings discharges (ρsvd) times the volume of the small...-cuttings discharges (kg) ρsvd = density of the small volume NAF-cuttings discharges (kg/bbl) VSVD = volume of the small volume NAF-cuttings discharges (bbl) The density of the small volume NAF-cuttings...

  8. 40 CFR Appendix 7 to Subpart A of... - Determination of the Amount of Non-Aqueous Drilling Fluid (NAF) Base Fluid From Drill Cuttings by...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... multiplying the density of the small volume NAF-cuttings discharges (ρsvd) times the volume of the small...-cuttings discharges (kg) ρsvd = density of the small volume NAF-cuttings discharges (kg/bbl) VSVD = volume of the small volume NAF-cuttings discharges (bbl) The density of the small volume NAF-cuttings...

  9. 40 CFR Appendix 7 to Subpart A of... - Determination of the Amount of Non-Aqueous Drilling Fluid (NAF) Base Fluid From Drill Cuttings by...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... multiplying the density of the small volume NAF-cuttings discharges (ρsvd) times the volume of the small...-cuttings discharges (kg) ρsvd = density of the small volume NAF-cuttings discharges (kg/bbl) VSVD = volume of the small volume NAF-cuttings discharges (bbl) The density of the small volume NAF-cuttings...

  10. Galaxy two-point covariance matrix estimation for next generation surveys

    NASA Astrophysics Data System (ADS)

    Howlett, Cullan; Percival, Will J.

    2017-12-01

    We perform a detailed analysis of the covariance matrix of the spherically averaged galaxy power spectrum and present a new, practical method for estimating this within an arbitrary survey without the need for running mock galaxy simulations that cover the full survey volume. The method uses theoretical arguments to modify the covariance matrix measured from a set of small-volume cubic galaxy simulations, which are computationally cheap to produce compared to larger simulations and match the measured small-scale galaxy clustering more accurately than is possible using theoretical modelling. We include prescriptions to analytically account for the window function of the survey, which convolves the measured covariance matrix in a non-trivial way. We also present a new method to include the effects of super-sample covariance and modes outside the small simulation volume which requires no additional simulations and still allows us to scale the covariance matrix. As validation, we compare the covariance matrix estimated using our new method to that from a brute-force calculation using 500 simulations originally created for analysis of the Sloan Digital Sky Survey Main Galaxy Sample. We find excellent agreement on all scales of interest for large-scale structure analysis, including those dominated by the effects of the survey window, and on scales where theoretical models of the clustering normally break down, but the new method produces a covariance matrix with significantly better signal-to-noise ratio. Although only formally correct in real space, we also discuss how our method can be extended to incorporate the effects of redshift space distortions.

  11. Generation of propagating backward volume spin waves by phase-sensitive mode conversion in two-dimensional microstructures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Braecher, T.; Sebastian, T.; Graduate School Materials Science in Mainz, Gottlieb-Daimler-Strasse 47, D-67663 Kaiserslautern

    2013-04-01

    We present the generation of propagating backward volume (BV) spin waves in a T shaped Ni{sub 81}Fe{sub 19} microstructure. These waves are created from counterpropagating Damon Eshbach spin waves, which are excited using microstrip antennas. By employing Brillouin light scattering microscopy, we show how the phase relation between the counterpropagating waves determines the mode generated in the center of the structure, and prove its propagation inside the longitudinally magnetized part of the T shaped microstructure. This gives access to the effective generation of backward volume spin waves with full control over the generated transverse mode.

  12. Aerosol optical properties of Western Mediterranean basin from multi-year AERONET data

    NASA Astrophysics Data System (ADS)

    Benkhalifa, Jamel; Léon, Jean François; Chaabane, Mabrouk

    2017-11-01

    Aerosol optical properties including the total and coarse mode aerosol extinction optical depth (AODt and AODc respectively), Angstrom exponent (AE), size distribution, single scattering albedo (SSA) were examined using long-term ground-based radiometric measurements at 9 sites in the Western Mediterranean: Oujda, Malaga, Barcelona, Carpentras, Rome Tor Vergata, Ersa, Ispra, Venice and Evora, during the 4-year study period (2010-2013). The South-North gradient in the fraction of AODc represents the signature of the increasing influence of coarse particles on the optical properties at southern stations. This fraction has a daily mean ranging from 48 ± 18% at the southern site Oujda and to 8 ± 8% at Ispra. The low average AE444-870 value (<0.7) at Oujda confirms the major influence of large dust particles. Conversely, the AOD at urban stations are dominated by fine mode particles. The Angstrom Exponent (AE444-870) above 1.5 in Ispra and Venice indicates an atmospheric situation corresponding to the urban pollution controlled by small particles. We have analyzed the intrinsic dust optical properties by selecting the dusty days corresponding to a total optical depth above 0.3 and a fraction of the coarse mode optical depth above 30%. For these cases, the mean AODt during dusty days was shown to be close to 0.4. During dusty days, the coarse mode fraction represents 88% of the total volume at Oudja and above 83% for all other sites. There is a weak variability in the mean coarse mode volume median radius, showing an average of 1.98 ± 0.1. A maximum in the AODc was observed in the summer of 2012, with particular high events on June 27. The forward trajectory starting at Evora on June 27 clearly indicates that all the sites were affected by such dust events in the following days.

  13. Assessment of renal injury with a clinical dual head lithotriptor delivering 240 shock waves per minute.

    PubMed

    Handa, Rajash K; McAteer, James A; Evan, Andrew P; Connors, Bret A; Pishchalnikov, Yuri A; Gao, Sujuan

    2009-02-01

    Lithotriptors with 2 treatment heads deliver shock waves along separate paths. Firing 1 head and then the other in alternating mode has been suggested as a strategy to treat stones twice as rapidly as with conventional shock wave lithotripsy. Because the shock wave rate is known to have a role in shock wave lithotripsy induced injury, and given that treatment using 2 separate shock wave sources exposes more renal tissue to shock wave energy than treatment with a conventional lithotriptor, we assessed renal trauma in pigs following treatment at rapid rate (240 shock waves per minute and 120 shock waves per minute per head) using a Duet lithotriptor (Direx Medical Systems, Petach Tikva, Israel) fired in alternating mode. Eight adult female pigs (Hardin Farms, Danville, Indiana) each were treated with sham shock wave lithotripsy or 2,400 shock waves delivered in alternating mode (1,200 shock waves per head, 120 shock waves per minute per head and 240 shock waves per minute overall at a power level of 10) to the lower renal pole. Renal functional parameters, including glomerular filtration rate and effective renal plasma flow, were determined before and 1 hour after shock wave lithotripsy. The kidneys were perfusion fixed in situ and the hemorrhagic lesion was quantified as a percent of functional renal volume. Shock wave treatment resulted in no significant change in renal function and the response was similar to the functional response seen in sham shock wave treated animals. In 6 pigs treated with alternating mode the renal lesion was small at a mean +/- SEM of 0.22% +/- 0.09% of functional renal volume. Kidney tissue and function were minimally affected by a clinical dose of shock waves delivered in alternating mode (120 shock waves per minute per head and 240 shock waves per minute overall) with a Duet lithotriptor. These observations decrease concern that dual head lithotripsy at a rapid rate is inherently dangerous.

  14. Can Black Hole Relax Unitarily?

    NASA Astrophysics Data System (ADS)

    Solodukhin, S. N.

    2005-03-01

    We review the way the BTZ black hole relaxes back to thermal equilibrium after a small perturbation and how it is seen in the boundary (finite volume) CFT. The unitarity requires the relaxation to be quasi-periodic. It is preserved in the CFT but is not obvious in the case of the semiclassical black hole the relaxation of which is driven by complex quasi-normal modes. We discuss two ways of modifying the semiclassical black hole geometry to maintain unitarity: the (fractal) brick wall and the worm-hole modification. In the latter case the entropy comes out correctly as well.

  15. Small ICBM Area Narrowing Report. Volume 1. Hard Mobile Launcher in Random Movement Basing Mode

    DTIC Science & Technology

    1986-01-01

    WHICH STATE INSTALLATION SERVICE ELIMINATED DE DOVER AIR FORCE BASE AF 4 DE REC AREA, FIRST ARMY ARMY 3 FL AVON PARK AIR FORCE RANGE AF 3 FL CAPE...PLANT NO. 47 AF 3 OH COLUMBUS DEF CONST SUPPLY CTR ARMY 4 OH COLUMBUS WEAPONS IND RES PLANT NAVY 3 OH EVANDALE PLANT NO. 36 AF 3 OH LIMA ARMY TANK...BLANK I I I I i I I I D-19 SENSITIVE FOR OFFICIAL USE ONLY 29I 331 J11 31 Alabam .._ _ . _ _ ............. _ . BAY MNETI ALLENTOW DE FUNII X0 LAN AT NO

  16. Exploration of Piezoelectric Bimorph Deflection in Synthetic Jet Actuators

    NASA Astrophysics Data System (ADS)

    Housley, Kevin; Amitay, Michael

    2017-11-01

    The design of piezoelectric bimorphs for synthetic jet actuators could be improved by greater understanding of the deflection of the bimorphs; both their mode shapes and the resulting volume change inside the actuator. The velocity performance of synthetic jet actuators is dependent on this volume change and the associated internal pressure changes. Knowledge of these could aid in refining the geometry of the cavity to improve efficiency. Phase-locked jet velocities and maps of displacement of the surface of the bimorph were compared between actuators of varying diameter. Results from a bimorph of alternate stiffness were also compared. Bimorphs with higher stiffness exhibited a more desirable (0,1) mode shape, which produced a high volume change inside of the actuator cavity. Those with lower stiffness allowed for greater displacement of the surface, initially increasing the volume change, but exhibited higher mode shapes at certain frequency ranges. These higher node shapes sharply reduced the volume change and negatively impacted the velocity of the jet at those frequencies. Adjustments to the distribution of stiffness along the radius of the bimorph could prevent this and allow for improved deflection without the risk of reaching higher modes.

  17. Retracted: Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation, by L Wang, SG Zellmer, DM Printzenhoff and NA Castle. British Journal of Pharmacology, volume 172(20): 4905-4918, published in October 2015; DOI 10.1111/bph.13259.

    PubMed

    2018-07-01

    The above article, published by the British Journal of Pharmacology in October 2015 (https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.13259), has been retracted by agreement between the authors, the journal Editor in Chief and John Wiley & Sons Limited. The retraction has been agreed owing to the discovery of errors in the chemical structure of the synthetic compounds generated. The corrected structure is now available in the article PF-06526290 can both enhance and inhibit conduction through voltage gated sodium channels by L Wang, SG Zellmer, DM Printzenhoff and NA Castle, 2018, https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14338. Reference Wang L, Zellmer SG, Printzenhoff DM, Castle NA (2015). Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation. Br J Pharmacol 172: 4905-4918. https://doi.org/10.1111/bph.13259. © 2018 The British Pharmacological Society.

  18. Preliminary evaluation of a liquid belt radiator for space applications

    NASA Technical Reports Server (NTRS)

    Teagan, W. P.; Fitzgerald, K.

    1984-01-01

    The liquid belt radiator (LBR) is discussed. The LBR system operates either in the sensible heat mode or in the latent heat mode. Parametric analysis shows that the LBR may reduce the mass of heat pipe radiators by 70 to 90% when the LBR surface has a total emissivity in excess of 0.3. It is indicated that the diffusion pump oils easily meet this criteria with emissivities greater than 0.8. Measurements on gallium indicate that its emissivity is probably in excess of 0.3 in the solid state when small amounts of impurities are on the surface. The point design exhibits a characteristic mass of 3.1 kg/kW of power dissipation, a mass per unit prime radiating area of approximately 0.9 kg/sq ms and a total package volume of approximately 2.50 cubic m. This compares favorably with conventional technologies which have weights on the order of 4 kg/sq m.

  19. 3D pulsed laser-triggered high-speed microfluidic fluorescence-activated cell sorter

    PubMed Central

    Chen, Yue; Wu, Ting-Hsiang; Kung, Yu-Chun; Teitell, Michael A.; Chiou, Pei-Yu

    2014-01-01

    We report a 3D microfluidic pulsed laser-triggered fluorescence-activated cell sorter capable of sorting at a throughput of 23,000 cells sec−1 with 90% purity in high-purity mode and at a throughput of 45,000 cells sec−1 with 45% purity in enrichment mode in one stage and in a single channel. This performance is realized by exciting laser-induced cavitation bubbles in a 3D PDMS microfluidic channel to generate high-speed liquid jets that deflect detected fluorescent cells and particles focused by 3D sheath flows. The ultrafast switching mechanism (20 μsec complete on-off cycle), small liquid jet perturbation volume, and three-dimensional sheath flow focusing for accurate timing control of fast (1.5 m sec−1) passing cells and particles are three critical factors enabling high-purity sorting at high-throughput in this sorter. PMID:23844418

  20. Stability of Lobed Balloons

    NASA Technical Reports Server (NTRS)

    Ball, Danny (Technical Monitor); Pagitz, M.; Pellegrino, Xu S.

    2004-01-01

    This paper presents a computational study of the stability of simple lobed balloon structures. Two approaches are presented, one based on a wrinkled material model and one based on a variable Poisson s ratio model that eliminates compressive stresses iteratively. The first approach is used to investigate the stability of both a single isotensoid and a stack of four isotensoids, for perturbations of in.nitesimally small amplitude. It is found that both structures are stable for global deformation modes, but unstable for local modes at su.ciently large pressure. Both structures are stable if an isotropic model is assumed. The second approach is used to investigate the stability of the isotensoid stack for large shape perturbations, taking into account contact between di.erent surfaces. For this structure a distorted, stable configuration is found. It is also found that the volume enclosed by this con.guration is smaller than that enclosed by the undistorted structure.

  1. A Longitudinal Mode Electromagnetic Acoustic Transducer (EMAT) Based on a Permanent Magnet Chain for Pipe Inspection.

    PubMed

    Cong, Ming; Wu, Xinjun; Qian, Chunqiao

    2016-05-21

    A new electromagnetic acoustic transducer (EMAT) design, employing a special structure of the permanent magnet chain, is proposed to generate and receive longitudinal guided waves for pipe inspection based on the magnetostriction mechanism. Firstly, a quantitative analysis of the excitation forces shows the influence of the radial component can be ignored. Furthermore, as the axial component of the static magnetic field is dominant, a method of solenoid testing coils connected in series is adopted to increase the signal amplitude. Then, two EMAT configurations are developed to generate and receive the L(0,2) guided wave mode. The experimental results show the circumferential notch can be identified and located successfully. Finally, a detailed investigation of the performance of the proposed EMATs is given. Compared to the conventional EMAT configuration, the proposed configurations have the advantages of small volume, light weight, easy installation and portability, which is helpful to improve inspection efficiency.

  2. Tunable cavity coupling of the zero phonon line of a nitrogen-vacancy defect in diamond

    NASA Astrophysics Data System (ADS)

    Johnson, S.; Dolan, P. R.; Grange, T.; Trichet, A. A. P.; Hornecker, G.; Chen, Y. C.; Weng, L.; Hughes, G. M.; Watt, A. A. R.; Auffèves, A.; Smith, J. M.

    2015-12-01

    We demonstrate the tunable enhancement of the zero phonon line of a single nitrogen-vacancy colour centre in diamond at cryogenic temperature. An open cavity fabricated using focused ion beam milling provides mode volumes as small as 1.24 μm3 (4.7 {λ }3) and quality factor Q≃ 3000. In situ tuning of the cavity resonance is achieved with piezoelectric actuators. At optimal coupling to a TEM00 cavity mode, the signal from individual zero phonon line transitions is enhanced by a factor of 6.25 and the overall emission rate of the NV- centre is increased by 40% compared with that measured from the same centre in the absence of cavity field confinement. This result represents a step forward in the realisation of efficient spin-photon interfaces and scalable quantum computing using optically addressable solid state spin qubits.

  3. Air-Gapped Structures as Magnetic Elements for Use in Power Processing Systems. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Ohri, A. K.

    1977-01-01

    Methodical approaches to the design of inductors for use in LC filters and dc-to-dc converters using air gapped magnetic structures are presented. Methods for the analysis and design of full wave rectifier LC filter circuits operating with the inductor current in both the continuous conduction and the discontinuous conduction modes are also described. In the continuous conduction mode, linear circuit analysis techniques are employed, while in the case of the discontinuous mode, the method of analysis requires computer solutions of the piecewise linear differential equations which describe the filter in the time domain. Procedures for designing filter inductors using air gapped cores are presented. The first procedure requires digital computation to yield a design which is optimized in the sense of minimum core volume and minimum number of turns. The second procedure does not yield an optimized design as defined above, but the design can be obtained by hand calculations or with a small calculator. The third procedure is based on the use of specially prepared magnetic core data and provides an easy way to quickly reach a workable design.

  4. Pressure and Thrust Measurements of a High-Frequency Pulsed Detonation Tube

    NASA Technical Reports Server (NTRS)

    Nguyen, N.; Cutler, A. D.

    2008-01-01

    This paper describes measurements of a small-scale, high-frequency pulsed detonation tube. The device utilized a mixture of H2 fuel and air, which was injected into the device at frequencies of up to 1200 Hz. Pulsed detonations were demonstrated in an 8-inch long combustion volume, at about 600 Hz, for the quarter wave mode of resonance. The primary objective of this experiment was to measure the generated thrust. A mean value of thrust was measured up to 6.0 lb, corresponding to H2 flow based specific impulse of 2970 s. This value is comparable to measurements in H2-fueled pulsed detonation engines (PDEs). The injection and detonation frequency for this new experimental case was much higher than typical PDEs, where frequencies are usually less than 100 Hz. The compact size of the device and high frequency of detonation yields a thrust-per-unit-volume of approximately 2.0 pounds per cubic inch, and compares favorably with other experiments, which typically have thrust-per-unit-volume of order 0.01 pound per cubic inch. This much higher volumetric efficiency results in a potentially much more practical device than the typical PDE, for a wide range of potential applications, including high-speed boundary layer separation control, for example in hypersonic engine inlets, and propulsion for small aircraft and missiles.

  5. Fusion splicing small-core photonic crystal fibers and single-mode fibers by repeated arc discharges.

    PubMed

    Xiao, Limin; Jin, Wei; Demokan, M S

    2007-01-15

    We demonstrate a novel method for low-loss splicing small-core photonic crystal fibers (PCFs) and single-mode fibers (SMFs) by repeated arc discharges using a conventional fusion splicer. An optimum mode field match at the interface of PCF-SMF and an adiabatic mode field variation in the longitudinal direction of the small-core PCF can be achieved by repeated arc discharges applied over the splicing joint to gradually collapse the air holes of the small-core PCF. This method is simple and offers a practical solution for light coupling between small-core PCFs and SMFs.

  6. Fusion splicing small-core photonic crystal fibers and single-mode fibers by repeated arc discharges

    NASA Astrophysics Data System (ADS)

    Xiao, Limin; Jin, Wei; Demokan, M. S.

    2007-01-01

    We demonstrate a novel method for low-loss splicing small-core photonic crystal fibers (PCFs) and single-mode fibers (SMFs) by repeated arc discharges using a conventional fusion splicer. An optimum mode field match at the interface of PCF-SMF and an adiabatic mode field variation in the longitudinal direction of the small-core PCF can be achieved by repeated arc discharges applied over the splicing joint to gradually collapse the air holes of the small-core PCF. This method is simple and offers a practical solution for light coupling between small-core PCFs and SMFs.

  7. Semiconductor Based Transverse Bragg Resonance (TBR) Optical Amplifiers and Lasers

    DTIC Science & Technology

    2007-02-14

    modes with small modal angles experience zero or very low radiation loss. We call these modes small modal angle (SMA) modes. SMA modes include both...lossless effective index-guided modes and low loss leaky modes. They are almost parallel to the graing and do not radiate significantly. As the modal...angle increases, all the modes experience higher radiation loss. However, around the transverse resonance angle of 13.80, low loss modes exist. These

  8. Life prediction methodology for ceramic components of advanced heat engines. Phase 1: Volume 2, Appendices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-03-01

    This volume presents the following appendices: ceramic test specimen drawings and schematics, mixed-mode and biaxial stress fracture of structural ceramics for advanced vehicular heat engines (U. Utah), mode I/mode II fracture toughness and tension/torsion fracture strength of NT154 Si nitride (Brown U.), summary of strength test results and fractography, fractography photographs, derivations of statistical models, Weibull strength plots for fast fracture test specimens, and size functions.

  9. 3-D ultrasound volume reconstruction using the direct frame interpolation method.

    PubMed

    Scheipers, Ulrich; Koptenko, Sergei; Remlinger, Rachel; Falco, Tony; Lachaine, Martin

    2010-11-01

    A new method for 3-D ultrasound volume reconstruction using tracked freehand 3-D ultrasound is proposed. The method is based on solving the forward volume reconstruction problem using direct interpolation of high-resolution ultrasound B-mode image frames. A series of ultrasound B-mode image frames (an image series) is acquired using the freehand scanning technique and position sensing via optical tracking equipment. The proposed algorithm creates additional intermediate image frames by directly interpolating between two or more adjacent image frames of the original image series. The target volume is filled using the original frames in combination with the additionally constructed frames. Compared with conventional volume reconstruction methods, no additional filling of empty voxels or holes within the volume is required, because the whole extent of the volume is defined by the arrangement of the original and the additionally constructed B-mode image frames. The proposed direct frame interpolation (DFI) method was tested on two different data sets acquired while scanning the head and neck region of different patients. The first data set consisted of eight B-mode 2-D frame sets acquired under optimal laboratory conditions. The second data set consisted of 73 image series acquired during a clinical study. Sample volumes were reconstructed for all 81 image series using the proposed DFI method with four different interpolation orders, as well as with the pixel nearest-neighbor method using three different interpolation neighborhoods. In addition, volumes based on a reduced number of image frames were reconstructed for comparison of the different methods' accuracy and robustness in reconstructing image data that lies between the original image frames. The DFI method is based on a forward approach making use of a priori information about the position and shape of the B-mode image frames (e.g., masking information) to optimize the reconstruction procedure and to reduce computation times and memory requirements. The method is straightforward, independent of additional input or parameters, and uses the high-resolution B-mode image frames instead of usually lower-resolution voxel information for interpolation. The DFI method can be considered as a valuable alternative to conventional 3-D ultrasound reconstruction methods based on pixel or voxel nearest-neighbor approaches, offering better quality and competitive reconstruction time.

  10. Zero-mode clad waveguides for performing spectroscopy with confined effective observation volumes

    DOEpatents

    Levene, Michael J.; Korlach, Jonas; Turner, Stephen W.; Craighead, Harold G.; Webb, Watt W.

    2005-07-12

    The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide.

  11. Apparatus and method for batch-wire continuous pumping

    DOEpatents

    Fassbender, Alexander G.

    1996-01-01

    The apparatus of the present invention contains at least one pressure vessel having a separator defining two chambers within each pressure vessel. The separator slideably seals the two chambers. Feedstock is placed within a second chamber adjoining the first chamber via a feedstock pump operating in a high volume low head mode. A pressurizer operates in a low volume high pressure mode to pressurize the working fluid and the feedstock in the pressure vessels to a process operating pressure. A circulating pump operates in a high volume, low head mode to circulate feedstock through the process. A fourth pump is used for moving feedstock and product at a pressure below the process operating pressure.

  12. Comparison of hand and semiautomatic tracing methods for creating maxillofacial artificial organs using sequences of computed tomography (CT) and cone beam computed tomography (CBCT) images.

    PubMed

    Szabo, Bence T; Aksoy, Seçil; Repassy, Gabor; Csomo, Krisztian; Dobo-Nagy, Csaba; Orhan, Kaan

    2017-06-09

    The aim of this study was to compare the paranasal sinus volumes obtained by manual and semiautomatic imaging software programs using both CT and CBCT imaging. 121 computed tomography (CT) and 119 cone beam computed tomography (CBCT) examinations were selected from the databases of the authors' institutes. The Digital Imaging and Communications in Medicine (DICOM) images were imported into 3-dimensonal imaging software, in which hand mode and semiautomatic tracing methods were used to measure the volumes of both maxillary sinuses and the sphenoid sinus. The determined volumetric means were compared to previously published averages. Isometric CBCT-based volume determination results were closer to the real volume conditions, whereas the non-isometric CT-based volume measurements defined coherently lower volumes. By comparing the 2 volume measurement modes, the values gained from hand mode were closer to the literature data. Furthermore, CBCT-based image measurement results corresponded to the known averages. Our results suggest that CBCT images provide reliable volumetric information that can be depended on for artificial organ construction, and which may aid the guidance of the operator prior to or during the intervention.

  13. Atomic-Scale Lightning Rod Effect in Plasmonic Picocavities: A Classical View to a Quantum Effect.

    PubMed

    Urbieta, Mattin; Barbry, Marc; Zhang, Yao; Koval, Peter; Sánchez-Portal, Daniel; Zabala, Nerea; Aizpurua, Javier

    2018-01-23

    Plasmonic gaps are known to produce nanoscale localization and enhancement of optical fields, providing small effective mode volumes of about a few hundred nm 3 . Atomistic quantum calculations based on time-dependent density functional theory reveal the effect of subnanometric localization of electromagnetic fields due to the presence of atomic-scale features at the interfaces of plasmonic gaps. Using a classical model, we explain this as a nonresonant lightning rod effect at the atomic scale that produces an extra enhancement over that of the plasmonic background. The near-field distribution of atomic-scale hot spots around atomic features is robust against dynamical screening and spill-out effects and follows the potential landscape determined by the electron density around the atomic sites. A detailed comparison of the field distribution around atomic hot spots from full quantum atomistic calculations and from the local classical approach considering the geometrical profile of the atoms' electronic density validates the use of a classical framework to determine the effective mode volume in these extreme subnanometric optical cavities. This finding is of practical importance for the community of surface-enhanced molecular spectroscopy and quantum nanophotonics, as it provides an adequate description of the local electromagnetic fields around atomic-scale features with use of simplified classical methods.

  14. [TRENDS OF PERMANENT PACEMAKER IMPLANTATION IN A SINGLE CENTER OVER A 20-YEAR PERIOD].

    PubMed

    Antonelli, Dante; Ilan, Limor Bushar; Freedberg, Nahum A; Feldman, Alexander; Turgeman, Yoav

    2015-05-01

    To review the changes in permanent pacemaker implantation indications, pacing modes and patients' demographics over a 20-year period. We retrospectively retrieved data on patients who underwent first implantation of the pacemaker between 1-1-1991 and 31-12-2010. One thousand and nine (1,009) patients underwent a first pacemaker implantation during that period; 535 were men (53%), their mean age was 74.6±19.5 years; the highest rate of implanted pacemaker was in patients ranging in age from 70-79 years, however there was an increasing number of patients aged over 80 years. The median survival time after initial pacemaker implantation was 8 years. Syncope was the most common symptom (62.5%) and atrioventricular block was the most common electrocardiographic indication (56.4%) leading to pacemaker implantation. There was increased utilization of dual chamber and rate responsive pacemakers over the years. There was no difference regarding mode selection between genders. Pacemaker implantation rates have increased over a 20-year period. Dual chamber replaced most of the single ventricular chamber pacemaker and rate responsive pacemakers became the norm. The data of a small volume center are similar to those reported in pacemaker surveys of high volume pacemaker implantation centers. They confirm adherence to the published guidelines for pacing.

  15. Collective strong coupling with homogeneous Rabi frequencies using a 3D lumped element microwave resonator

    NASA Astrophysics Data System (ADS)

    Angerer, Andreas; Astner, Thomas; Wirtitsch, Daniel; Sumiya, Hitoshi; Onoda, Shinobu; Isoya, Junichi; Putz, Stefan; Majer, Johannes

    2016-07-01

    We design and implement 3D-lumped element microwave cavities that spatially focus magnetic fields to a small mode volume. They allow coherent and uniform coupling to electron spins hosted by nitrogen vacancy centers in diamond. We achieve large homogeneous single spin coupling rates, with an enhancement of more than one order of magnitude compared to standard 3D cavities with a fundamental resonance at 3 GHz. Finite element simulations confirm that the magnetic field distribution is homogeneous throughout the entire sample volume, with a root mean square deviation of 1.54%. With a sample containing 1017 nitrogen vacancy electron spins, we achieve a collective coupling strength of Ω = 12 MHz, a cooperativity factor C = 27, and clearly enter the strong coupling regime. This allows to interface a macroscopic spin ensemble with microwave circuits, and the homogeneous Rabi frequency paves the way to manipulate the full ensemble population in a coherent way.

  16. A path to practical Solar Pumped Lasers via Radiative Energy Transfer

    DOE PAGES

    Reusswig, Philip D.; Nechayev, Sergey; Scherer, Jennifer M.; ...

    2015-10-05

    The optical conversion of incoherent solar radiation into a bright, coherent laser beam enables the application of nonlinear optics to solar energy conversion and storage. Here, we present an architecture for solar pumped lasers that uses a luminescent solar concentrator to decouple the conventional trade-off between solar absorption efficiency and the mode volume of the optical gain material. We report a 750-μm-thick Nd 3+ -doped YAG planar waveguide sensitized by a luminescent CdSe/CdZnS (core/shell) colloidal nanocrystal, yielding a peak cascade energy transfer of 14%, a broad spectral response in the visible portion of the solar spectrum, and an equivalent quasi-CWmore » solar lasing threshold of 23 W-cm -2, or approximately 230 suns. The efficient coupling of incoherent, spectrally broad sunlight in small gain volumes should allow the generation of coherent laser light from intensities of less than 100 suns.« less

  17. A path to practical Solar Pumped Lasers via Radiative Energy Transfer

    PubMed Central

    Reusswig, Philip D.; Nechayev, Sergey; Scherer, Jennifer M.; Hwang, Gyu Weon; Bawendi, Moungi G.; Baldo, Marc. A.; Rotschild, Carmel

    2015-01-01

    The optical conversion of incoherent solar radiation into a bright, coherent laser beam enables the application of nonlinear optics to solar energy conversion and storage. Here, we present an architecture for solar pumped lasers that uses a luminescent solar concentrator to decouple the conventional trade-off between solar absorption efficiency and the mode volume of the optical gain material. We report a 750-μm-thick Nd3+-doped YAG planar waveguide sensitized by a luminescent CdSe/CdZnS (core/shell) colloidal nanocrystal, yielding a peak cascade energy transfer of 14%, a broad spectral response in the visible portion of the solar spectrum, and an equivalent quasi-CW solar lasing threshold of 23 W-cm−2, or approximately 230 suns. The efficient coupling of incoherent, spectrally broad sunlight in small gain volumes should allow the generation of coherent laser light from intensities of less than 100 suns. PMID:26434400

  18. A path to practical Solar Pumped Lasers via Radiative Energy Transfer.

    PubMed

    Reusswig, Philip D; Nechayev, Sergey; Scherer, Jennifer M; Hwang, Gyu Weon; Bawendi, Moungi G; Baldo, Marc A; Rotschild, Carmel

    2015-10-05

    The optical conversion of incoherent solar radiation into a bright, coherent laser beam enables the application of nonlinear optics to solar energy conversion and storage. Here, we present an architecture for solar pumped lasers that uses a luminescent solar concentrator to decouple the conventional trade-off between solar absorption efficiency and the mode volume of the optical gain material. We report a 750-μm-thick Nd(3+)-doped YAG planar waveguide sensitized by a luminescent CdSe/CdZnS (core/shell) colloidal nanocrystal, yielding a peak cascade energy transfer of 14%, a broad spectral response in the visible portion of the solar spectrum, and an equivalent quasi-CW solar lasing threshold of 23 W-cm(-2), or approximately 230 suns. The efficient coupling of incoherent, spectrally broad sunlight in small gain volumes should allow the generation of coherent laser light from intensities of less than 100 suns.

  19. The CCTC Quick-Reacting General War Gaming System (QUICK) Users Manual. Volume 3. Weapon Allocation Subsystem

    DTIC Science & Technology

    1978-04-15

    analyst who is concerned with preparing the data base for a war game, selecting optional features of QUICK, designating control parameters, submitting...i/.,-j-t r? 70 ~ CoMPUIfE YsTIEM MANUAL CSM UM 9-77 VOLUME IIIC15 APRIL 1978 Lod COMMAND 9 \\.., & CONTROL 09 TECHNICAL . CENTER CCTC QUICK-REACTING...RECALC Mode ............................... 31 3.1.1.2 Non -RECALC Mode ........................... 31 3.1.1.3 Mode Selecti-n and JCL Consideration

  20. Control of second-harmonic generation in doubly resonant aluminum nitride microrings to address a rubidium two-photon clock transition.

    PubMed

    Surya, Joshua B; Guo, Xiang; Zou, Chang-Ling; Tang, Hong X

    2018-06-01

    Nonlinear optical effects have been studied extensively in microresonators as more photonics applications transitions to integrated on-chip platforms. Due to low optical losses and small mode volumes, microresonators are demonstrably the state-of-the-art platform for second-harmonic generation (SHG). However, the working bandwidth of such microresonator-based devices is relatively small, presenting a challenge for applications where a specifically targeted wavelength needs to be addressed. In this Letter, we analyze the phase-matching window and resonance wavelength with respect to varying microring widths, radii, and temperatures. A chip with precise design parameters was fabricated with phase matching realized at the exact wavelength of a two-photon transition of Rb85. This procedure can be generalized to any target pump wavelength in the telecom band with picometer precision.

  1. Optical engine initiation: multiple compartment applications

    NASA Astrophysics Data System (ADS)

    Hunt, Jeffrey H.

    2009-05-01

    Modern day propulsion systems are used in aerospace applications for different purposes. The aerospace industry typically requires propulsion systems to operate in a rocket mode in order to drive large boost vehicles. The defense industry generally requires propulsion systems to operate in an air-breathing mode in order to drive missiles. A mixed system could use an air-breathing first stage and a rocket-mode upper stage for space access. Thus, propulsion systems can be used for high mass payloads and where the payload is dominated by the fuel/oxidizer mass being used by the propulsion system. The pulse detonation wave engine (PDWE) uses an alternative type of detonation cycle to achieve the same propulsion results. The primary component of the PDWE is the combustion chamber (or detonation tube). The PDWE represents an attractive propulsion source since its engine cycle is thermodynamically closest to that of a constant volume reaction. This characteristic leads to the inference that a maximum of the potential energy of the PDWE is put into thrust and not into flow work. Consequently, the volume must be increased. The technical community has increasingly adopted the alternative choice of increasing total volume by designing the engine to include a set of banks of smaller combustion chambers. This technique increases the complexity of the ignition subsystem because the inter-chamber timing must be considered. Current approaches to igniting the PDWE have involved separate shock or blast wave initiators and chemical additives designed to enhance detonatibility. An optical ignition subsystem generates a series of optical pulses, where the optical pulses ignite the fuel/oxidizer mixture such that the chambers detonate in a desired order. The detonation system also has an optical transport subsystem for transporting the optical pulses from the optical ignition subsystem to the chambers. The use of optical ignition and transport provides a non-toxic, small, lightweight, precisely controlled detonation system.

  2. The Methodology of Selecting the Transport Mode for Companies on the Slovak Transport Market

    NASA Astrophysics Data System (ADS)

    Černá, Lenka; Zitrický, Vladislav; Daniš, Jozef

    2017-03-01

    Transport volume in the Slovak Republic is growing continuously every year. This rising trend is influenced by the development of car industry and its suppliers. Slovak republic has also a geographic strategy position in middle Europe from the side of transport corridors (east-west and north-south). The development of transport volume in freight transport depends on the transport and business processes between the European Union and China and it is an opportunity for Slovak republic to obtain transit transport flows. In the Slovak Republic, road transport has a dominant position in the transport market. The volume of road transport has gradually increased over the past years. The increase of road transport is reflected on the highways and speed roads in regions which have higher economic potential. The increase of rail transport as seen on the main rail corridors is not as significant as in road transport. Trade globalization also has an influence on the increase of transport volume in intermodal transport. Predicted increase in transport volume for this transport mode is from 2,3 mil ton per year at present to 8 mil ton in the year 2020. Selection of transport mode and carrier is an important aspect for logistic management, because companies (customers) want to reduce the number of carriers which they trade and they create the system of several key carriers. Bigger transport volume and more qualitative transport service give a possibility to reduce transport costs. This trend is positive for carriers too, because the carriers can focus only on the selected customers and provide more qualitative services. The paper is focused on the selection of transport mode based on the proposed methodology. The aims of the paper are, definition of criteria which directly influence the selection of transport modes, determination of criteria based on the subjectively methods, creation of process for the selection of transport modes and practical application of proposed methodology.

  3. The TMI Regenerative Solid Oxide Fuel Cell

    NASA Technical Reports Server (NTRS)

    Cable, Thomas L.; Ruhl, Robert C.; Petrik, Michael

    1996-01-01

    Energy storage and production in space requires rugged, reliable hardware which minimizes weight, volume, and maintenance while maximizing power output and usable energy storage. Systems generally consist of photovoltaic solar arrays which operate (during sunlight cycles) to provide system power and regenerate fuel (hydrogen) via water electrolysis and (during dark cycles) fuel cells convert hydrogen into electricity. Common configurations use two separate systems (fuel cell and electrolyzer) in conjunction with photovoltaic cells. Reliability, power to weight and power to volume ratios could be greatly improved if both power production (fuel cells) and power storage (electrolysis) functions can be integrated into a single unit. The solid oxide fuel cell (SOFC) based design integrates fuel cell and electrolyzer functions and potentially simplifies system requirements. The integrated fuel cell/electrolyzer design also utilizes innovative gas storage concepts and operates like a rechargeable 'hydrogen-oxygen battery'. Preliminary research has been completed on improved H2/H20 electrode (SOFC anode/electrolyzer cathode) materials for regenerative fuel cells. Tests have shown improved cell performance in both fuel and electrolysis modes in reversible fuel cell tests. Regenerative fuel cell efficiencies, ratio of power out (fuel cell mode) to power in (electrolyzer mode), improved from 50 percent using conventional electrode materials to over 80 percent. The new materials will allow a single SOFC system to operate as both the electolyzer and fuel cell. Preliminary system designs have also been developed to show the technical feasibility of using the design for space applications requiring high energy storage efficiencies and high specific energy. Small space systems also have potential for dual-use, terrestrial applications.

  4. A Tabletop Persistent-Mode, Liquid-Helium-Free, 1.5-T/90-mm MgB2 “Finger” MRI Magnet for Osteoporosis Screening: Two Design Options

    PubMed Central

    Park, Dongkeun; Bascuñán, Juan; Michael, Philip C.; Iwasa, Yukikazu

    2017-01-01

    In this paper we present two design options for a tabletop liquid-helium-free, persistent-mode 1.5-T/90-mm MgB2 “finger” MRI magnet for osteoporosis screening. Both designs, one with and the other without an iron yoke, satisfy the following criteria: 1) 1.5-T center field with a 90-mm room-temperature bore for a finger to be placed at the magnet center; 2) spatial field homogeneity of <5 ppm over a 20-mm diameter of spherical volume (DSV); 3) persistent-mode operation with temporal stability of <0.1 ppm/hr; 4) liquid-helium-free operation; 5) 5-gauss fringe field radius of <50 cm from the magnet center; and 6) small and light enough for placement on an exam table. Although the magnet is designed to operate nominally at 10 K, maintained by a cryocooler, it has a 5-K temperature margin to keep its 1.5-T persistent field up to 15 K. The magnet will be immersed in a volume of solid nitrogen (SN2) that provides additional thermal mass when the cryocooler is switched off to provide a vibration-free measurement environment. The SN2 enables the magnet to maintain its persistent field over a period of time sufficient for quiescent measurement, while still limiting the magnet operating temperature to ≤15 K. We discuss first pros and cons of each design, and then further studies of our proposed MgB2 finger MRI magnet. PMID:29456437

  5. A Tabletop Persistent-Mode, Liquid-Helium-Free, 1.5-T/90-mm MgB2 "Finger" MRI Magnet for Osteoporosis Screening: Two Design Options.

    PubMed

    Park, Dongkeun; Bascuñán, Juan; Michael, Philip C; Iwasa, Yukikazu

    2018-04-01

    In this paper we present two design options for a tabletop liquid-helium-free, persistent-mode 1.5-T/90-mm MgB 2 "finger" MRI magnet for osteoporosis screening. Both designs, one with and the other without an iron yoke, satisfy the following criteria: 1) 1.5-T center field with a 90-mm room-temperature bore for a finger to be placed at the magnet center; 2) spatial field homogeneity of <5 ppm over a 20-mm diameter of spherical volume (DSV); 3) persistent-mode operation with temporal stability of <0.1 ppm/hr; 4) liquid-helium-free operation; 5) 5-gauss fringe field radius of <50 cm from the magnet center; and 6) small and light enough for placement on an exam table. Although the magnet is designed to operate nominally at 10 K, maintained by a cryocooler, it has a 5-K temperature margin to keep its 1.5-T persistent field up to 15 K. The magnet will be immersed in a volume of solid nitrogen (SN 2 ) that provides additional thermal mass when the cryocooler is switched off to provide a vibration-free measurement environment. The SN 2 enables the magnet to maintain its persistent field over a period of time sufficient for quiescent measurement, while still limiting the magnet operating temperature to ≤15 K. We discuss first pros and cons of each design, and then further studies of our proposed MgB 2 finger MRI magnet.

  6. Investigation into the visual perceptive ability of anaesthetists during ultrasound-guided interscalene and femoral blocks conducted on soft embalmed cadavers: a randomised single-blind study.

    PubMed

    Mustafa, A; Seeley, J; Munirama, S; Columb, M; McKendrick, M; Schwab, A; Corner, G; Eisma, R; Mcleod, G

    2018-04-01

    Errors may occur during regional anaesthesia whilst searching for nerves, needle tips, and test doses. Poor visual search impacts on decision making, clinical intervention, and patient safety. We conducted a randomised single-blind study in a single university hospital. Twenty trainees and two consultants examined the paired B-mode and fused B-mode and elastography video recordings of 24 interscalene and 24 femoral blocks conducted on two soft embalmed cadavers. Perineural injection was randomised equally to 0.25, 0.5, and 1.0 ml volumes. Tissue displacement perceived on both imaging modalities was defined as 'target' or 'distractor'. Our primary objective was to test the anaesthetists' perception of the number and proportion of targets and distractors on B-mode and fused elastography videos collected during femoral and sciatic nerve block on soft embalmed cadavers. Our secondary objectives were to determine the differences between novices and experts, and between test-dose volumes, and to measure the area and brightness of spread and strain patterns. All anaesthetists recognised perineural spread using 0.25 ml volumes. Distractor patterns were recognised in 133 (12%) of B-mode and in 403 (38%) of fused B-mode and elastography patterns; P<0.001. With elastography, novice recognition improved from 12 to 37% (P<0.001), and consultant recognition increased from 24 to 53%; P<0.001. Distractor recognition improved from 8 to 31% using 0.25 ml volumes (P<0.001), and from 15 to 45% using 1 ml volumes (P<0.001). Visual search improved with fusion elastography, increased volume, and consultants. A need exists to investigate image search strategies. Copyright © 2018 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.

  7. A Compact Microwave Microfluidic Sensor Using a Re-Entrant Cavity.

    PubMed

    Hamzah, Hayder; Abduljabar, Ali; Lees, Jonathan; Porch, Adrian

    2018-03-19

    A miniaturized 2.4 GHz re-entrant cavity has been designed, manufactured and tested as a sensor for microfluidic compositional analysis. It has been fully evaluated experimentally with water and common solvents, namely methanol, ethanol, and chloroform, with excellent agreement with the expected behaviour predicted by the Debye model. The sensor's performance has also been assessed for analysis of segmented flow using water and oil. The samples' interaction with the electric field in the gap region has been maximized by aligning the sample tube parallel to the electric field in this region, and the small width of the gap (typically 1 mm) result in a highly localised complex permittivity measurement. The re-entrant cavity has simple mechanical geometry, small size, high quality factor, and due to the high concentration of electric field in the gap region, a very small mode volume. These factors combine to result in a highly sensitive, compact sensor for both pure liquids and liquid mixtures in capillary or microfluidic environments.

  8. The Use of Cryogenically Cooled 5A Molecular Sieves for Large Volume Reduction of Tritiated Hydrogen Gas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Antoniazzi, A.B.; Bartoszek, F.E.; Sherlock, A.M.

    2006-07-01

    A commercial hydrogen isotope separation system based on gas chromatography (AGC-ISS) has been built. The system operates in two modes: stripping and volume reduction. The purpose of the stripping mode is to reduce a large volume of tritiated hydrogen gas to a small volume of tritium rich hydrogen gas. The results here illustrate the effectiveness of the AGC-ISS in the stripping and volume reduction phases. Column readiness for hydrogen isotope separation is confirmed by room temperature air separation tests. Production runs were initially carried out using natural levels of deuterium (110-160 ppm) in high purity hydrogen. After completion of themore » deuterium/hydrogen runs the system began operations with tritiated hydrogen. The paper presents details of the AGC-ISS design and results of tritium tests. The heart of the AGC-ISS consists of two packed columns (9 m long, 3.8 cm OD) containing 5A molecular sieve material of 40/60 mesh size. Each column has 5 individually controlled heaters along the length of the column and is coiled around an inverted inner dewar. The coiled column and inner dewar are both contained within an outer dewar. In this arrangement liquid nitrogen, used to cryogenically cool the columns, flows into and out off the annular space defined by the two dewars, allowing for alternate heating and cooling cycles. Tritiated hydrogen feed is injected in batch quantities. The batch size is variable with the maximum quantity restricted by the tritium concentration in the exhausted hydrogen. The stripping operations can be carried out in full automated mode or in full manual mode. The average cycle time between injections is about 75 minutes. To date, the maximum throughput achieved is 10.5 m{sup 3}/day. A total of 37.8 m{sup 3} of tritiated hydrogen has been processed during commissioning. The system has demonstrated that venting of >99.95% of the feed gas is possible while retaining 99.98% of the tritium. At a maximum tritium concentration of {approx}7 GBq/m{sup 3} (190 mCi/m{sup 3}), processing tritiated hydrogen gas at a rate of 8.1 m{sup 3} (NTP)/day results in an average tritium concentration in the process effluent line of 1.4 MBq/m{sup 3} (37 {mu}Ci/m{sup 3}). The average process exhaust flow, split between helium and hydrogen, is 10.6 litre/min. Product from the stripping phase is stored on a 5 kg depleted uranium bed. A 250 g depleted uranium bed is available for storage of enriched product. Several, ionization type, tritium sensors are located throughout the process to control emissions, control valve switching, and monitor evolution of tritiated species from the columns. (authors)« less

  9. Ultralow mode-volume photonic crystal nanobeam cavities for high-efficiency coupling to individual carbon nanotube emitters

    PubMed Central

    Miura, R.; Imamura, S.; Ohta, R.; Ishii, A.; Liu, X.; Shimada, T.; Iwamoto, S.; Arakawa, Y.; Kato, Y. K.

    2014-01-01

    The unique emission properties of single-walled carbon nanotubes are attractive for achieving increased functionality in integrated photonics. In addition to being room-temperature telecom-band emitters that can be directly grown on silicon, they are ideal for coupling to nanoscale photonic structures. Here we report on high-efficiency coupling of individual air-suspended carbon nanotubes to silicon photonic crystal nanobeam cavities. Photoluminescence images of dielectric- and air-mode cavities reflect their distinctly different mode profiles and show that fields in the air are important for coupling. We find that the air-mode cavities couple more efficiently, and estimated spontaneous emission coupling factors reach a value as high as 0.85. Our results demonstrate advantages of ultralow mode-volumes in air-mode cavities for coupling to low-dimensional nanoscale emitters. PMID:25420679

  10. The effect of closed system suction on airway pressures when using the Servo 300 ventilator.

    PubMed

    Frengley, R W; Closey, D N; Sleigh, J W; Torrance, J M

    2001-12-01

    To measure airway pressures during closed system suctioning with the ventilator set to three differing modes of ventilation. Closed system suctioning was conducted in 16 patients following cardiac surgery. Suctioning was performed using a 14 French catheter with a vacuum level of -500 cmH2O through an 8.0 mm internal diameter endotracheal tube. The lungs were mechanically ventilated with a Servo 300 ventilator set to one of three ventilation modes: volume-control, pressure-control or CPAP/pressure support. Airway pressures were measured via a 4 French electronic pressure transducer in both proximal and distal airways. Following insertion of the suction catheter, end-expiratory pressure increased significantly (p < 0.001) in both pressure-control and volume-control ventilation. This increase was greatest (p = 0.018) in volume-control mode (2.7 +/- 1.7 cmH2O). On performing a five second suction, airway pressure decreased in all modes, however the lowest airway pressure in volume-control mode (-4.9 +/- 4.0 cmH2O) was significantly (p = 0.001) less than the lowest airway pressure recorded in either pressure-control (0.8 +/- 1.9 cmH2O) or CPAP/pressure support (0.4 +/- 2.8 cmH2O) modes. In CPAP/pressure support mode, 13 of the 16 patients experienced a positive pressure 'breath' at the end of suctioning with airway pressures rising to 21 +/- 1.6 cmH2O. Closed system suctioning in volume control ventilation may result in elevations of end-expiratory pressure following catheter insertion and subatmospheric airway pressures during suctioning. Pressure control ventilation produces less elevation of end-expiratory pressure following catheter insertion and is less likely to be associated with subatmospheric airway pressures during suctioning. CPAP/pressure support has no effect on end-expiratory pressure following catheter insertion and subatmospheric airway pressures are largely avoided during suctioning.

  11. The Dependence of Cirrus Gamma Size Distributions Expressed as Volumes in N(sub 0)-Lambda-Mu Phase Space and Bulk Cloud Properties on Environmental Conditions: Results from the Small Ice Particles in Cirrus Experiment (SPARTICUS)

    NASA Technical Reports Server (NTRS)

    Jackson, Robert C.; McFarquhar, Greg M.; Fridlind, Ann M.; Atlas, Rachel

    2015-01-01

    The variability of cirrus ice microphysical properties is investigated using observations obtained during the Small Particles in Cirrus (SPARTICUS) campaign. An existing approach that represents a size distribution (SD) as a single gamma function using an ellipsoid of equally realizable solutions in (N(sub 0), lambda, mu) phase space is modified to automatically identify multiple modes in SDs and characterize each mode by such an ellipsoid. The modified approach is applied to ice crystals with maximum dimension D greater than15 micrometers collected by the 2-D stereo and 2-D precipitation probes on the Stratton Park Engineering Company Learjet. The dependencies of N(sub 0), mu, and lambda from each mode, total number concentration, bulk extinction, ice water content (IWC), and mass median maximum dimension D(sub mm) as a function of temperature T and cirrus type are then analyzed. The changes in the observed codependencies between N(sub 0), mu, and lambda, bulk extinction, IWC, and D(sub mm) with environmental conditions indicate that particles were larger at higher T during SPARTICUS. At most two modes were observed in any SD during SPARTICUS, with the average boundary between them at 115 micrometers, similar to past studies not using probes with shatter mitigating tips and artifact removal algorithms. The bimodality of the SDs increased with T. This and the differences in N(sub 0), mu, and lambda between the modes suggest that particles with smaller D nucleated more recently than particles with larger D, which grew via vapor deposition and aggregation. Because smaller crystals, whose concentrations are uncertain, make marginal contributions to higher order moments, the use of higher moments for evaluating model fields is suggested.

  12. Automated SEM Modal Analysis Applied to the Diogenites

    NASA Technical Reports Server (NTRS)

    Bowman, L. E.; Spilde, M. N.; Papike, James J.

    1996-01-01

    Analysis of volume proportions of minerals, or modal analysis, is routinely accomplished by point counting on an optical microscope, but the process, particularly on brecciated samples such as the diogenite meteorites, is tedious and prone to error by misidentification of very small fragments, which may make up a significant volume of the sample. Precise volume percentage data can be gathered on a scanning electron microscope (SEM) utilizing digital imaging and an energy dispersive spectrometer (EDS). This form of automated phase analysis reduces error, and at the same time provides more information than could be gathered using simple point counting alone, such as particle morphology statistics and chemical analyses. We have previously studied major, minor, and trace-element chemistry of orthopyroxene from a suite of diogenites. This abstract describes the method applied to determine the modes on this same suite of meteorites and the results of that research. The modal abundances thus determined add additional information on the petrogenesis of the diogenites. In addition, low-abundance phases such as spinels were located for further analysis by this method.

  13. Pressure and Thrust Measurements of a High-Frequency Pulsed-Detonation Actuator

    NASA Technical Reports Server (NTRS)

    Nguyen, Namtran C.; Cutler, Andrew D.

    2008-01-01

    This paper describes the development of a small-scale, high-frequency pulsed detonation actuator. The device utilized a fuel mixture of H2 and air, which was injected into the device at frequencies of up to 1200 Hz. Pulsed detonations were demonstrated in an 8-inch long combustion volume, at approx.600 Hz, for the lambda/4 mode. The primary objective of this experiment was to measure the generated thrust. A mean value of thrust was measured up to 6.0 lb, corresponding to specific impulse of 2611 s. This value is comparable to other H2-fueled pulsed detonation engines (PDEs) experiments. The injection and detonation frequency for this new experimental case was approx.600 Hz, and was much higher than typical PDEs, where frequencies are usually less than 100 Hz. The compact size of the model and high frequency of detonation yields a thrust-per-unit-volume of approximately 2.0 lb/cu in, and compares favorably with other experiments, which typically have thrust-per-unit-volume values of approximately 0.01 lb/cu in.

  14. Instabilities and subharmonic resonances of subsonic heated round jets, volume 2. Ph.D. Thesis Final Report

    NASA Technical Reports Server (NTRS)

    Ng, Lian Lai

    1990-01-01

    When a jet is perturbed by a periodic excitation of suitable frequency, a large-scale coherent structure develops and grows in amplitude as it propagates downstream. The structure eventually rolls up into vortices at some downstream location. The wavy flow associated with the roll-up of a coherent structure is approximated by a parallel mean flow and a small, spatially periodic, axisymmetric wave whose phase velocity and mode shape are given by classical (primary) stability theory. The periodic wave acts as a parametric excitation in the differential equations governing the secondary instability of a subharmonic disturbance. The (resonant) conditions for which the periodic flow can strongly destabilize a subharmonic disturbance are derived. When the resonant conditions are met, the periodic wave plays a catalytic role to enhance the growth rate of the subharmonic. The stability characteristics of the subharmonic disturbance, as a function of jet Mach number, jet heating, mode number and the amplitude of the periodic wave, are studied via a secondary instability analysis using two independent but complementary methods: (1) method of multiple scales, and (2) normal mode analysis. It is found that the growth rates of the subharmonic waves with azimuthal numbers beta = 0 and beta = 1 are enhanced strongly, but comparably, when the amplitude of the periodic wave is increased. Furthermore, compressibility at subsonic Mach numbers has a moderate stabilizing influence on the subharmonic instability modes. Heating suppresses moderately the subharmonic growth rate of an axisymmetric mode, and it reduces more significantly the corresponding growth rate for the first spinning mode. Calculations also indicate that while the presence of a finite-amplitude periodic wave enhances the growth rates of subharmonic instability modes, it minimally distorts the mode shapes of the subharmonic waves.

  15. How kinetics drives the two- to three-dimensional transition in semiconductor strained heterostructures: The case of InAs/GaAs(001)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arciprete, F.; Placidi, E.; Sessi, V.

    2006-07-24

    The two- to three-dimensional growth mode transition in the InAs/GaAs(001) heterostructure has been investigated by means of atomic force microscopy. The kinetics of the density of three-dimensional islands indicates two transition onsets at 1.45 and 1.59 ML of InAs coverage, corresponding to two separate families, small and large dots. According to the scaling analysis and volume measurements, the transition between the two families of quantum dots and the explosive nucleation of the large ones is triggered by the erosion of the step edges.

  16. Investigation of Condensed Media in Weak Fields by the Method of Nuclear Magnetic Resonance

    NASA Astrophysics Data System (ADS)

    Davydov, V. V.; Myazin, N. S.; Dudkin, V. I.; Velichko, E. N.

    2018-05-01

    A compact design of a rapid-response nuclear magnetic spectrometer for investigation of condensed media in weak fields is reported. As a result of investigation of different condensed media, special features of recording a nuclear magnetic resonance (NMR) signal in a weak magnetic field from a small volume of the medium under study are established. For the first time the NMR absorption spectra of condensed media in a weak field are collected. Based on the results of experimental studies, the potential of using a compact NMR-spectrometer for condensed media monitoring in a rapid response mode is determined.

  17. Ultracompact low-threshold organic laser.

    PubMed

    Deotare, Parag B; Mahony, Thomas S; Bulović, Vladimir

    2014-11-25

    We report an ultracompact low-threshold laser with an Alq3:DCM host:guest molecular organic thin film gain layer. The device uses a photonic crystal nanobeam cavity which provides a high quality factor to mode volume (Q/V) ratio and increased spontaneous emission factor along with a small footprint. Lasing is observed with a threshold of 4.2 μJ/cm(2) when pumped by femtosecond pulses of λ = 400 nm wavelength light. We also model the dynamics of the laser and show good agreement with the experimental data. The inherent waveguide geometry of the structure enables easy on-chip integration with potential applications in biochemical sensing, inertial sensors, and data communication.

  18. Ultra-low power fiber-coupled gallium arsenide photonic crystal cavity electro-optic modulator.

    PubMed

    Shambat, Gary; Ellis, Bryan; Mayer, Marie A; Majumdar, Arka; Haller, Eugene E; Vučković, Jelena

    2011-04-11

    We demonstrate a gallium arsenide photonic crystal cavity injection-based electro-optic modulator coupled to a fiber taper waveguide. The fiber taper serves as a convenient and tunable waveguide for cavity coupling with minimal loss. Localized electrical injection of carriers into the cavity region via a laterally doped p-i-n diode combined with the small mode volume of the cavity enable ultra-low energy modulation at sub-fJ/bit levels. Speeds of up to 1 GHz are demonstrated with photoluminescence lifetime measurements revealing that the ultimate limit goes well into the tens of GHz. © 2011 Optical Society of America

  19. Proceedings of the International Conference on Stiff Computation, April 12-14, 1982, Park City, Utah. Volume III.

    DTIC Science & Technology

    1982-01-01

    The symbolic generation of the Jacobian fy would then be Scomparatively trivial, if a full mode updating scheme were applied (where each entry of f... scheme in LARKIN are on one - hand rather concise and on the other hand general enough to -n permit the use of any of the presently ava2.lable sparse sol...sufficiently small, I W(z)-a(z)I< ch In (X-X )I with u=xh. When X i o, W(s (u)) is the diagonal Padd approximation tsf1 8e he general first-order (Wl1 : first

  20. Silicon nano-membrane based photonic crystal microcavities for high sensitivity bio-sensing.

    PubMed

    Lai, Wei-Cheng; Chakravarty, Swapnajit; Zou, Yi; Chen, Ray T

    2012-04-01

    We experimentally demonstrated photonic crystal microcavity based resonant sensors coupled to photonic crystal waveguides in silicon nano-membrane on insulator for chemical and bio-sensing. Linear L-type microcavities are considered. In contrast to cavities with small mode volumes, but low quality factors for bio-sensing, we showed increasing the length of the microcavity enhances the quality factor of the resonance by an order of magnitude and increases the resonance wavelength shift while retaining compact device characteristics. Q~26760 and sensitivity down to 15 ng/ml and ~110 pg/mm2 in bio-sensing was experimentally demonstrated on silicon-on-insulator devices.

  1. Design evaluations for a flight cloud physics holocamera. [holographic/photographic camera for low-g Atmospheric Cloud Physics Laboratory

    NASA Technical Reports Server (NTRS)

    Moore, W. W., Jr.; Kurtz, R. L.; Lemons, J. F.

    1976-01-01

    The paper describes a holographic/photographic camera to be used with the zero-g or low-g Atmospheric Cloud Physics Laboratory. The flight prototype holocamera is intended to record particles from 0.01 to 5 microns for an optimum two-dimensional plane only in the microscopic photography mode, particles on a volume basis in the in-line holography mode from 5 microns up, and all particle sizes possible on a volume basis in the acute sideband holography mode.

  2. Parameter study of dual-mode space nuclear fission solid core power and propulsion systems, NUROC3A. AMS report No. 1239c

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, W.W.; Layton, J.P.

    1976-09-13

    The three-volume report describes a dual-mode nuclear space power and propulsion system concept that employs an advanced solid-core nuclear fission reactor coupled via heat pipes to one of several electric power conversion systems. The NUROC3A systems analysis code was designed to provide the user with performance characteristics of the dual-mode system. Volume 3 describes utilization of the NUROC3A code to produce a detailed parameter study of the system.

  3. 40 CFR 86.1826-01 - Assigned deterioration factors for small volume manufacturers and small volume test groups.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... durability groups) that is equipped with unproven emission control systems. (v) The manufacturer must... small volume manufacturers and small volume test groups. 86.1826-01 Section 86.1826-01 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW...

  4. 40 CFR 86.1826-01 - Assigned deterioration factors for small volume manufacturers and small volume test groups.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... durability groups) that is equipped with unproven emission control systems. (v) The manufacturer must... small volume manufacturers and small volume test groups. 86.1826-01 Section 86.1826-01 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW...

  5. 40 CFR 86.1826-01 - Assigned deterioration factors for small volume manufacturers and small volume test groups.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... durability groups) that is equipped with unproven emission control systems. (v) The manufacturer must... small volume manufacturers and small volume test groups. 86.1826-01 Section 86.1826-01 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW...

  6. 40 CFR 86.1826-01 - Assigned deterioration factors for small volume manufacturers and small volume test groups.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... durability groups) that is equipped with unproven emission control systems. (v) The manufacturer must... small volume manufacturers and small volume test groups. 86.1826-01 Section 86.1826-01 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW...

  7. Waveguides for performing spectroscopy with confined effective observation volumes

    DOEpatents

    Levene, Michael J.; Korlach, Jonas; Turner, Stephen W.; Craighead, Harold G.; Webb, Watt W.

    2006-03-14

    The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide.

  8. Resonant Mode-hopping Micromixing

    PubMed Central

    Jang, Ling-Sheng; Chao, Shih-Hui; Holl, Mark R.; Meldrum, Deirdre R.

    2009-01-01

    A common micromixer design strategy is to generate interleaved flow topologies to enhance diffusion. However, problems with these designs include complicated structures and dead volumes within the flow fields. We present an active micromixer using a resonating piezoceramic/silicon composite diaphragm to generate acoustic streaming flow topologies. Circulation patterns are observed experimentally and correlate to the resonant mode shapes of the diaphragm. The dead volumes in the flow field are eliminated by rapidly switching from one discrete resonant mode to another (i.e., resonant mode-hop). Mixer performance is characterized by mixing buffer with a fluorescence tracer containing fluorescein. Movies of the mixing process are analyzed by converting fluorescent images to two-dimensional fluorescein concentration distributions. The results demonstrate that mode-hopping operation rapidly homogenized chamber contents, circumventing diffusion-isolated zones. PMID:19551159

  9. FLOW-i ventilator performance in the presence of a circle system leak.

    PubMed

    Lucangelo, Umberto; Ajčević, Miloš; Accardo, Agostino; Borelli, Massimo; Peratoner, Alberto; Comuzzi, Lucia; Zin, Walter A

    2017-04-01

    Recently, the FLOW-i anaesthesia ventilator was developed based on the SERVO-i intensive care ventilator. The aim of this study was to test the FLOW-i's tidal volume delivery in the presence of a leak in the breathing circuit. We ventilated a test lung model in volume-, pressure-, and pressure-regulated volume-controlled modes (VC, PC, and PRVC, respectively) with a FLOW-i. First, the circuit remained airtight and the ventilator was tested with fresh gas flows of 6, 1, and 0.3 L/min in VC, PC, and PRVC modes and facing 4 combinations of different resistive and elastic loads. Second, a fixed leak in the breathing circuit was introduced and the measurements repeated. In the airtight system, FLOW-i maintained tidal volume (VT) and circuit pressure at approximately the set values, independently of respiratory mode, load, or fresh gas flow. In the leaking circuit, set VT = 500 mL, FLOW-i delivered higher VTs in PC (about 460 mL) than in VC and PRVC, where VTs were substantially less than 500 mL. Interestingly, VT did not differ appreciably from 6 to 0.3 L/min of fresh air flow among the 3 ventilatory modes. In the absence of leakage, peak inspiratory pressures were similar, while they were 35-45 % smaller in PRVC and VC than in PC mode in the presence of leaks. In conclusion, FLOW-i maintained VT (down to fresh gas flows of 0.3 L/min) to 90 % of its preset value in PC mode, which was 4-5 times greater than in VC or PRVC modes.

  10. Mode demultiplexer using angularly multiplexed volume holograms.

    PubMed

    Wakayama, Yuta; Okamoto, Atsushi; Kawabata, Kento; Tomita, Akihisa; Sato, Kunihiro

    2013-05-20

    This study proposes a volume holographic demultiplexer (VHDM) for extracting the spatial modes excited in a multimode fiber. A unique feature of the demultiplexer is that it can separate a number of multiplexed modes output from a fiber in different directions by using multi-recorded holograms without beam splitters, which results in a simple configuration as compared with that using phase plates instead of holograms. In this study, an experiment is conducted to demonstrate the basic operations for three LP mode groups to confirm the performance of the proposed VHDM and to estimate the signal-to-crosstalk noise ratio (SNR). As a result, an SNR of greater than 20 dB is obtained.

  11. Pseudolinear gradient ultrahigh-pressure liquid chromatography using an injection valve assembly.

    PubMed

    Xiang, Yanqiao; Liu, Yansheng; Stearns, Stanley D; Plistil, Alex; Brisbin, Martin P; Lee, Milton L

    2006-02-01

    The use of ultrahigh pressures in liquid chromatography (UHPLC) imposes stringent requirements on hardware such as pumps, valves, injectors, connecting tubing, and columns. One of the most difficult components of the UHPLC system to develop has been the sample injector. Static-split injection, which can be performed at pressures up to 6900 bar (100,000 psi), consumes a large sample volume and is very irreproducible. A pressure-balanced injection valve provided better reproducibility, shorter injection time, reduced sample consumption, and greater ease of use; however, it could only withstand pressures up to approximately 1000 bar (15,000 psi). In this study, a new injection valve assembly that can operate at pressures as high as 2070 bar (30,000 psi) was evaluated for UHPLC. This assembly contains six miniature electronically controlled needle valves to provide accurate and precise volumes for introduction into the capillary LC column. It was found that sample volumes as small as several tenths of a nanoliter can be injected, which are comparable to the results obtained from the static-split injector. The reproducibilities of retention time, efficiency, and peak area were investigated, and the results showed that the relative standard deviations of these parameters were small enough for quantitative analyses. Separation experiments using the UHPLC system with this new injection valve assembly showed that this new injector is suitable for both isocratic and gradient operation modes. A newly designed capillary connector was used at a pressure as high as 2070 bar (30,000 psi).

  12. Transpiring purging access probe for particulate laden or hazardous environments

    DOEpatents

    VanOsdol, John G

    2013-12-03

    An access probe for remote-sensing access through a viewing port, viewing volume, and access port into a vessel. The physical boundary around the viewing volume is partially formed by a porous sleeve lying between the viewing volume and a fluid conduit. In a first mode of operation, a fluid supplied to the fluid conduit encounters the porous sleeve and flows through the porous material to maintain the viewing volume free of ash or other matter. When additional fluid force is needed to clear the viewing volume, the pressure of the fluid flow is increased sufficiently to slidably translate the porous sleeve, greatly increasing the flow into the viewing volume. The porous sleeve is returned to position by an actuating spring. The access probe thereby provides for alternate modes of operation based on the pressure of an actuating fluid.

  13. Raman Frequencies Calculated from the Volume Data as a Function of Temperature at High Pressures for the Disordered Phase II of NH4I

    NASA Astrophysics Data System (ADS)

    Yurtseven, H.; Kavruk, D.

    In this study, we calculate the Raman frequencies as a function of temperature for the fixed pressures of 706, 1080 and 6355 bars using the volume data for phase II of ammonium iodide. The Raman frequencies calculated here are for the translational optic ν5 TOM (125 cm-1) lattice mode that is located at the zone boundary (M point) of the Brillouin zone of phase II for NH4I. For this calculation the volume data obtained at zero pressure, is used through the mode Grüneisen parameter for the disordered phase II (β phase) which has the CsCl structure of NH4I. Our predicted frequencies of the ν5 TOM (125 cm-1) mode can be compared when the Raman data for this lattice mode is available at various temperatures for fixed pressures of 706, 1080 and 6355 bars in the disordered phase II of ammonium iodide.

  14. On the strength of random fiber networks

    NASA Astrophysics Data System (ADS)

    Deogekar, S.; Picu, R. C.

    2018-07-01

    Damage accumulation and failure in random fiber networks is of importance in a variety of applications, from design of synthetic materials, such as paper and non-wovens, to accidental tearing of biological tissues. In this work we study these processes using three-dimensional models of athermal fiber networks, focusing attention on the modes of failure and on the relationship between network strength and network structural parameters. We consider network failure at small and large strains associated with the rupture of inter-fiber bonds. It is observed that the strength increases linearly with the network volume fraction and with the bond strength, while the stretch at peak stress is inversely related to these two parameters. A small fraction of the bonds rupture before peak stress and this fraction increases with increasing failure stretch. Rendering the bond strength stochastic causes a reduction of the network strength. However, heterogeneity retards damage localization and increases the stretch at peak stress, therefore promoting ductility.

  15. CO2 laser-driven Stirling engine. [space power applications

    NASA Technical Reports Server (NTRS)

    Lee, G.; Perry, R. L.; Carney, B.

    1978-01-01

    A 100-W Beale free-piston Stirling engine was powered remotely by a CO2 laser for long periods of time. The engine ran on both continuous-wave and pulse laser input. The working fluid was helium doped with small quantities of sulfur hexafluoride, SF6. The CO2 radiation was absorbed by the vibrational modes of the sulfur hexafluoride, which in turn transferred the energy to the helium to drive the engine. Electrical energy was obtained from a linear alternator attached to the piston of the engine. Engine pressures, volumes, and temperatures were measured to determine engine performance. It was found that the pulse radiation mode was more efficient than the continuous-wave mode. An analysis of the engine heat consumption indicated that heat losses around the cylinder and the window used to transmit the beam into the engine accounted for nearly half the energy input. The overall efficiency, that is, electrical output to laser input, was approximately 0.75%. However, this experiment was not designed for high efficiency but only to demonstrate the concept of a laser-driven engine. Based on this experiment, the engine could be modified to achieve efficiencies of perhaps 25-30%.

  16. AOF LTAO mode: reconstruction strategy and first test results

    NASA Astrophysics Data System (ADS)

    Oberti, Sylvain; Kolb, Johann; Le Louarn, Miska; La Penna, Paolo; Madec, Pierre-Yves; Neichel, Benoit; Sauvage, Jean-François; Fusco, Thierry; Donaldson, Robert; Soenke, Christian; Suárez Valles, Marcos; Arsenault, Robin

    2016-07-01

    GALACSI is the Adaptive Optics (AO) system serving the instrument MUSE in the framework of the Adaptive Optics Facility (AOF) project. Its Narrow Field Mode (NFM) is a Laser Tomography AO (LTAO) mode delivering high resolution in the visible across a small Field of View (FoV) of 7.5" diameter around the optical axis. From a reconstruction standpoint, GALACSI NFM intends to optimize the correction on axis by estimating the turbulence in volume via a tomographic process, then projecting the turbulence profile onto one single Deformable Mirror (DM) located in the pupil, close to the ground. In this paper, the laser tomographic reconstruction process is described. Several methods (virtual DM, virtual layer projection) are studied, under the constraint of a single matrix vector multiplication. The pseudo-synthetic interaction matrix model and the LTAO reconstructor design are analysed. Moreover, the reconstruction parameter space is explored, in particular the regularization terms. Furthermore, we present here the strategy to define the modal control basis and split the reconstruction between the Low Order (LO) loop and the High Order (HO) loop. Finally, closed loop performance obtained with a 3D turbulence generator will be analysed with respect to the most relevant system parameters to be tuned.

  17. Elastomeric Microchip Electrospray Emitter for Stable Cone-Jet Mode Operation in the Nano-Flow Regime

    PubMed Central

    Kelly, Ryan T.; Tang, Keqi; Irimia, Daniel; Toner, Mehmet; Smith, Richard D.

    2009-01-01

    Despite widespread interest in combining lab-on-a-chip technologies with mass spectrometry (MS)-based analyses, the coupling of microfluidics to electrospray ionization (ESI)-MS remains challenging. We report a robust, integrated poly(dimethylsiloxane) microchip interface for ESI-MS using simple and widely accessible microfabrication procedures. The interface uses an auxiliary channel to provide electrical contact for the stable cone-jet electrospray without sample loss or dilution. The electric field at the channel terminus is enhanced by two vertical cuts that cause the interface to taper to a line rather than to a point, and the formation of a small Taylor cone at the channel exit ensures sub-nL post-column dead volumes. Cone-jet mode electrospray was demonstrated for up to 90% aqueous solutions and for extended durations. Comparable ESI-MS sensitivities were achieved using both microchip and conventional fused silica capillary emitters, but stable cone-jet mode electrosprays could be established over a far broader range of flow rates (from 50-1000 nL/min) and applied potentials using the microchip emitters. This attribute of the microchip emitter should simplify electrospray optimization and make the stable electrospray more resistant to external perturbations. PMID:18419138

  18. Assessing patterns of spatial behavior in health studies: their socio-demographic determinants and associations with transportation modes (the RECORD Cohort Study).

    PubMed

    Perchoux, Camille; Kestens, Yan; Thomas, Frédérique; Van Hulst, Andraea; Thierry, Benoit; Chaix, Basile

    2014-10-01

    Prior epidemiological studies have mainly focused on local residential neighborhoods to assess environmental exposures. However, individual spatial behavior may modify residential neighborhood influences, with weaker health effects expected for mobile populations. By examining individual patterns of daily mobility and associated socio-demographic profiles and transportation modes, this article seeks to develop innovative methods to account for daily mobility in health studies. We used data from the RECORD Cohort Study collected in 2011-2012 in the Paris metropolitan area, France. A sample of 2062 individuals was investigated. Participants' perceived residential neighborhood boundaries and regular activity locations were geocoded using the VERITAS application. Twenty-four indicators were created to qualify individual space-time patterns, using spatial analysis methods and a geographic information system. Three domains of indicators were considered: lifestyle indicators, indicators related to the geometry of the activity space, and indicators related to the importance of the residential neighborhood in the overall activity space. Principal component analysis was used to identify main dimensions of spatial behavior. Multilevel linear regression was used to determine which individual characteristics were associated with each spatial behavior dimension. The factor analysis generated five dimensions of spatial behavior: importance of the residential neighborhood in the activity space, volume of activities, and size, eccentricity, and specialization of the activity space. Age, socioeconomic status, and location of the household in the region were the main predictors of daily mobility patterns. Activity spaces of small sizes centered on the residential neighborhood and implying a large volume of activities were associated with walking and/or biking as a transportation mode. Examination of patterns of spatial behavior by individual socio-demographic characteristics and in relation to transportation modes is useful to identify populations with specific mobility/accessibility needs and has implications for investigating transportation-related physical activity and assessing environmental exposures and their effects on health. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Normal modes of weak colloidal gels

    NASA Astrophysics Data System (ADS)

    Varga, Zsigmond; Swan, James W.

    2018-01-01

    The normal modes and relaxation rates of weak colloidal gels are investigated in calculations using different models of the hydrodynamic interactions between suspended particles. The relaxation spectrum is computed for freely draining, Rotne-Prager-Yamakawa, and accelerated Stokesian dynamics approximations of the hydrodynamic mobility in a normal mode analysis of a harmonic network representing several colloidal gels. We find that the density of states and spatial structure of the normal modes are fundamentally altered by long-ranged hydrodynamic coupling among the particles. Short-ranged coupling due to hydrodynamic lubrication affects only the relaxation rates of short-wavelength modes. Hydrodynamic models accounting for long-ranged coupling exhibit a microscopic relaxation rate for each normal mode, λ that scales as l-2, where l is the spatial correlation length of the normal mode. For the freely draining approximation, which neglects long-ranged coupling, the microscopic relaxation rate scales as l-γ, where γ varies between three and two with increasing particle volume fraction. A simple phenomenological model of the internal elastic response to normal mode fluctuations is developed, which shows that long-ranged hydrodynamic interactions play a central role in the viscoelasticity of the gel network. Dynamic simulations of hard spheres that gel in response to short-ranged depletion attractions are used to test the applicability of the density of states predictions. For particle concentrations up to 30% by volume, the power law decay of the relaxation modulus in simulations accounting for long-ranged hydrodynamic interactions agrees with predictions generated by the density of states of the corresponding harmonic networks as well as experimental measurements. For higher volume fractions, excluded volume interactions dominate the stress response, and the prediction from the harmonic network density of states fails. Analogous to the Zimm model in polymer physics, our results indicate that long-ranged hydrodynamic interactions play a crucial role in determining the microscopic dynamics and macroscopic properties of weak colloidal gels.

  20. Comparison of gating methods for the real-time analysis of left ventricular function in nonimaging blood pool studies.

    PubMed

    Beard, B B; Stewart, J R; Shiavi, R G; Lorenz, C H

    1995-01-01

    Gating methods developed for electrocardiographic-triggered radionuclide ventriculography are being used with nonimaging detectors. These methods have not been compared on the basis of their real-time performance or suitability for determination of load-independent indexes of left ventricular function. This work evaluated the relative merits of different gating methods for nonimaging radionuclude ventriculographic studies, with particular emphasis on their suitability for real-time measurements and the determination of pressure-volume loops. A computer model was used to investigate the relative accuracy of forward gating, backward gating, and phase-mode gating. The durations of simulated left ventricular time-activity curves were randomly varied. Three acquisition parameters were considered: frame rate, acceptance window, and sample size. Twenty-five studies were performed for each combination of acquisition parameters. Hemodynamic and shape parameters from each study were compared with reference parameters derived directly from the random time-activity curves. Backward gating produced the largest errors under all conditions. For both forward gating and phase-mode gating, ejection fraction was underestimated and time to end systole and normalized peak ejection rate were overestimated. For the hemodynamic parameters, forward gating was marginally superior to phase-mode gating. The mean difference in errors between forward and phase-mode gating was 1.47% (SD 2.78%). However, for root mean square shape error, forward gating was several times worse in every case and seven times worse than phase-mode gating on average. Both forward and phase-mode gating are suitable for real-time hemodynamic measurements by nonimaging techniques. The small statistical difference between the methods is not clinically significant. The true shape of the time-activity curve is maintained most accurately by phase-mode gating.

  1. Comparison of gating methods for the real-time analysis of left ventricular function in nonimaging blood pool studies

    PubMed Central

    Beard, Brian B.; Stewart, James R.; Shiavi, Richard G.; Lorenz, Christine H.

    2018-01-01

    Background Gating methods developed for electrocardiographic-triggered radionuclide ventriculography are being used with nonimaging detectors. These methods have not been compared on the basis of their real-time performance or suitability for determination of load-independent indexes of left ventricular function. This work evaluated the relative merits of different gating methods for nonimaging radionuclude ventriculographic studies, with particular emphasis on their suitability for real-time measurements and the determination of pressure-volume loops. Methods and Results A computer model was used to investigate the relative accuracy of forward gating, backward gating, and phase-mode gating. The durations of simulated left ventricular time-activity curves were randomly varied. Three acquisition parameters were considered: frame rate, acceptance window, and sample size. Twenty-five studies were performed for each combination of acquisition parameters. Hemodynamic and shape parameters from each study were compared with reference parameters derived directly from the random time-activity curves. Backward gating produced the largest errors under all conditions. For both forward gating and phase-mode gating, ejection fraction was underestimated and time to end systole and normalized peak ejection rate were overestimated. For the hemodynamic parameters, forward gating was marginally superior to phase-mode gating. The mean difference in errors between forward and phase-mode gating was 1.47% (SD 2.78%). However, for root mean square shape error, forward gating was several times worse in every case and seven times worse than phase-mode gating on average. Conclusions Both forward and phase-mode gating are suitable for real-time hemodynamic measurements by nonimaging techniques. The small statistical difference between the methods is not clinically significant. The true shape of the time-activity curve is maintained most accurately by phase-mode gating. PMID:9420820

  2. Simulating the effect of non-linear mode coupling in cosmological parameter estimation

    NASA Astrophysics Data System (ADS)

    Kiessling, A.; Taylor, A. N.; Heavens, A. F.

    2011-09-01

    Fisher Information Matrix methods are commonly used in cosmology to estimate the accuracy that cosmological parameters can be measured with a given experiment and to optimize the design of experiments. However, the standard approach usually assumes both data and parameter estimates are Gaussian-distributed. Further, for survey forecasts and optimization it is usually assumed that the power-spectrum covariance matrix is diagonal in Fourier space. However, in the low-redshift Universe, non-linear mode coupling will tend to correlate small-scale power, moving information from lower to higher order moments of the field. This movement of information will change the predictions of cosmological parameter accuracy. In this paper we quantify this loss of information by comparing naïve Gaussian Fisher matrix forecasts with a maximum likelihood parameter estimation analysis of a suite of mock weak lensing catalogues derived from N-body simulations, based on the SUNGLASS pipeline, for a 2D and tomographic shear analysis of a Euclid-like survey. In both cases, we find that the 68 per cent confidence area of the Ωm-σ8 plane increases by a factor of 5. However, the marginal errors increase by just 20-40 per cent. We propose a new method to model the effects of non-linear shear-power mode coupling in the Fisher matrix by approximating the shear-power distribution as a multivariate Gaussian with a covariance matrix derived from the mock weak lensing survey. We find that this approximation can reproduce the 68 per cent confidence regions of the full maximum likelihood analysis in the Ωm-σ8 plane to high accuracy for both 2D and tomographic weak lensing surveys. Finally, we perform a multiparameter analysis of Ωm, σ8, h, ns, w0 and wa to compare the Gaussian and non-linear mode-coupled Fisher matrix contours. The 6D volume of the 1σ error contours for the non-linear Fisher analysis is a factor of 3 larger than for the Gaussian case, and the shape of the 68 per cent confidence volume is modified. We propose that future Fisher matrix estimates of cosmological parameter accuracies should include mode-coupling effects.

  3. MEGARA spectrograph optics

    NASA Astrophysics Data System (ADS)

    Carrasco, E.; Sánchez-Blanco, E.; García-Vargas, M. L.; Gil de Paz, A.; Páez, G.; Gallego, J.; Sánchez, F. M.; Vílchez, J. M.

    2012-09-01

    MEGARA is the next optical Integral-Field Unit (IFU) and Multi-Object Spectrograph (MOS) for Gran Telescopio Canarias. The instrument offers two IFUs plus a Multi-Object Spectroscopy (MOS) mode: a large compact bundle covering 12.5 arcsec x 11.3 arcsec on sky with 100 μm fiber-core; a small compact bundle, of 8.5 arcsec x 6.7 arcsec with 70 μm fiber-core and a fiber MOS positioner that allows to place up to 100 mini-bundles, 7 fibers each, with 100 μm fiber-core, within a 3.5 arcmin x 3.5 arcmin field of view, around the two IFUs. The fibers, organized in bundles, end in the pseudo-slit plate, which will be placed at the entrance focal plane of the MEGARA spectrograph. The large IFU and MOS modes will provide intermediate to high spectral resolutions, R=6800-17000. The small IFU mode will provide R=8000-20000. All these resolutions are possible thanks to a spectrograph design based in the used of volume phase holographic gratings in combination with prisms to keep fixed the collimator and camera angle. The MEGARA optics is composed by a total of 53 large optical elements per spectrograph: the field lens, the collimator and the camera lenses plus the complete set of pupil elements including holograms, windows and prisms. INAOE, a partner of the GTC and a partner of MEGARA consortium, is responsible of the optics manufacturing and tests. INAOE will carry out this project working in an alliance with CIO. This paper summarizes the status of MEGARA spectrograph optics at the Preliminary Design Review, held on March 2012.

  4. Analysis of Dual Mode Systems in an Urban Area : Volume 4A. Program Documentation of the Transportation Economic Analysis Model.

    DOT National Transportation Integrated Search

    1973-12-01

    Various forms of Dual Mode Transportation were analyzed in order to assess the economic viability of the Dual Mode concept. A Dual Mode vehicle is one which operates under manual control on a streee network for some portionof its trip, and operates u...

  5. The dynamics and control of large flexible space structures. Volume 3, part B: The modelling, dynamics, and stability of large Earth pointing orbiting structures

    NASA Technical Reports Server (NTRS)

    Bainum, P. M.; Kumar, V. K.

    1980-01-01

    The dynamics and stability of large orbiting flexible beams, and platforms and dish type structures oriented along the local horizontal are treated both analytically and numerically. It is assumed that such structures could be gravitationally stabilized by attaching a rigid light-weight dumbbell at the center of mass by a spring loaded hinge which also could provide viscous damping. For the beam, the small amplitude inplane pitch motion, dumbbell librational motion, and the anti-symmetric elastic modes are all coupled. The three dimensional equations of motion for a circular flat plate and shallow spherical shell in orbit with a two-degree-of freedom gimballed dumbbell are also developed and show that only those elastic modes described by a single nodal diameter line are influenced by the dumbbell motion. Stability criteria are developed for all the examples and a sensitivity study of the system response characteristics to the key system parameters is carried out.

  6. A Longitudinal Mode Electromagnetic Acoustic Transducer (EMAT) Based on a Permanent Magnet Chain for Pipe Inspection

    PubMed Central

    Cong, Ming; Wu, Xinjun; Qian, Chunqiao

    2016-01-01

    A new electromagnetic acoustic transducer (EMAT) design, employing a special structure of the permanent magnet chain, is proposed to generate and receive longitudinal guided waves for pipe inspection based on the magnetostriction mechanism. Firstly, a quantitative analysis of the excitation forces shows the influence of the radial component can be ignored. Furthermore, as the axial component of the static magnetic field is dominant, a method of solenoid testing coils connected in series is adopted to increase the signal amplitude. Then, two EMAT configurations are developed to generate and receive the L(0,2) guided wave mode. The experimental results show the circumferential notch can be identified and located successfully. Finally, a detailed investigation of the performance of the proposed EMATs is given. Compared to the conventional EMAT configuration, the proposed configurations have the advantages of small volume, light weight, easy installation and portability, which is helpful to improve inspection efficiency. PMID:27213400

  7. Nondestructive characterization of UHMWPE armor materials

    NASA Astrophysics Data System (ADS)

    Chiou, Chien-Ping; Margetan, Frank J.; Barnard, Daniel J.; Hsu, David K.; Jensen, Terrence; Eisenmann, David

    2012-05-01

    Ultra-high molecular weight polyethylene (UHMWPE) is a material increasingly used for fabricating helmet and body armor. In this work, plate specimens consolidated from thin fiber sheets in series 3124 and 3130 were examined with ultrasound, X-ray and terahertz radiation. Ultrasonic through-transmission scans using both air-coupled and immersion modes revealed that the 3130 series material generally had much lower attenuation than the 3124 series, and that certain 3124 plates had extremely high attenuation. Due to the relatively low inspection frequencies used, pulse-echo immersion ultrasonic testing could not detect distinct flaw echoes from the interior. To characterize the nature of the defective condition that was responsible for the high ultrasonic attenuation, terahertz radiation in the time-domain spectroscopy mode were used to image the flaws. Terahertz scan images obtained on the high attenuation samples clearly showed a distribution of a large number of defects, possibly small planar delaminations, throughout the volume of the interior. Their precise nature and morphology are to be verified by optical microscopy of the sectioned surface.

  8. High performance concentration method for viruses in drinking water.

    PubMed

    Kunze, Andreas; Pei, Lu; Elsässer, Dennis; Niessner, Reinhard; Seidel, Michael

    2015-09-15

    According to the risk assessment of the WHO, highly infectious pathogenic viruses like rotaviruses should not be present in large-volume drinking water samples of up to 90 m(3). On the other hand, quantification methods for viruses are only operable in small volumes, and presently no concentration procedure for processing such large volumes has been reported. Therefore, the aim of this study was to demonstrate a procedure for processing viruses in-line of a drinking water pipeline by ultrafiltration (UF) and consecutive further concentration by monolithic filtration (MF) and centrifugal ultrafiltration (CeUF) of viruses to a final 1-mL sample. For testing this concept, the model virus bacteriophage MS2 was spiked continuously in UF instrumentation. Tap water was processed in volumes between 32.4 m(3) (22 h) and 97.7 m(3) (72 h) continuously either in dead-end (DE) or cross-flow (CF) mode. Best results were found by DE-UF over 22 h. The concentration of MS2 was increased from 4.2×10(4) GU/mL (genomic units per milliliter) to 3.2×10(10) GU/mL and from 71 PFU/mL to 2×10(8) PFU/mL as determined by qRT-PCR and plaque assay, respectively. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Methodologies for Verification and Validation of Space Launch System (SLS) Structural Dynamic Models: Appendices

    NASA Technical Reports Server (NTRS)

    Coppolino, Robert N.

    2018-01-01

    Verification and validation (V&V) is a highly challenging undertaking for SLS structural dynamics models due to the magnitude and complexity of SLS subassemblies and subassemblies. Responses to challenges associated with V&V of Space Launch System (SLS) structural dynamics models are presented in Volume I of this paper. Four methodologies addressing specific requirements for V&V are discussed. (1) Residual Mode Augmentation (RMA). (2) Modified Guyan Reduction (MGR) and Harmonic Reduction (HR, introduced in 1976). (3) Mode Consolidation (MC). Finally, (4) Experimental Mode Verification (EMV). This document contains the appendices to Volume I.

  10. Discriminant analysis to predict the occurrence of ELMS in H-mode discharges

    NASA Astrophysics Data System (ADS)

    Kardaun, O. J. W. F.; Itoh, S.-I.; Itoh, K.; Kardaun, J. W. P. F.

    1993-08-01

    After an exposition of its theoretical background, discriminant analysis is applied to the H-mode confinement database to find the region in plasma parameter space in which H-mode with small ELM's (Edge Localized Modes) is likely to occur. The boundary of this region is determined by the condition that the probability of appearance of such a type of H-mode, as a function of the plasma parameters, should be larger than some threshold value and larger than the corresponding probability for other types of H-mode (i.e., H-mode without ELM's or with giant ELM's). In practice, the discrimination has been performed for the ASDEX, JET and JFT-2M tokamaks using four instantaneous plasma parameters (injected power Pinj, magnetic field Bt, plasma current Ip and line averaged electron density ne) and taking also memory effects of the plasma and the distance between the plasma and the wall into account, while using variables that are normalized with respect to machine size. Generally speaking, it is found that there is a substantial overlap between the region of H-mode with small ELM's and the region of the two other types of H-mode. However, the ELM-free and the giant ELM H-modes relatively rarely appear in the region, that, according to the analysis, is allocated to small ELM's. A reliable production of H-mode with only small ELM's seems well possible by choosing this regime in parameter space. In the present study, it was not attempted to arrive at a unified discrimination across the machines. So, projection from one machine to another remains difficult, and a reliable determination of the region where small ELM's occur still requires a training sample from the device under consideration.

  11. Characteristic analysis and comparison of two kinds of hybrid plasmonic annular resonators

    NASA Astrophysics Data System (ADS)

    Zhou, Jie; Shi, Feifei; Zhou, Taojie; He, Kebo; Qiu, Bocang; Zhang, Zhaoyu

    2017-04-01

    We designed two kinds of hybrid plasmonic annular resonators with different cross-sectional shapes, i.e., a square and circle called "square ring" and "circle ring" resonators, respectively. Both resonators feature an ultracompact mode volume of ˜10-4 μm3 and a relatively high-quality factor of ˜102 at a submicron footprint within our studied wavelength range from 400 to 900 nm. Their performance as defined by the Q/V ratio (quality factor over mode volume) is enhanced considerably with a reduction in their physical dimensions. There exists critical annular radii, which increase from 400 to 600 nm with an increase in the azimuthal numbers from m=7 to m=10, if the two types of rings are compared with the same mode numbers and same ring thickness of 120 nm. Below the critical radii, the circle ring resonator outperforms the square ring resonator in terms of the Q/V ratio, and the difference in Q/V of the two types of rings increases rapidly with the decrease of the radii. On the other hand, they have critical annular radii of ˜250 nm, below which the square ring resonator outperforms the circle ring resonator at the wavelengths of 490 and 595 nm however, the difference in Q/V of the two types of rings remains small within the radii range we consider. It is suggested that, in practice, with the consideration of the wavelength of green emission for these two ring structures with radii from 100 to 500 nm and ring thickness ˜120 nm, they have a negligible difference in Q/V performance.

  12. SU-F-P-07: Applying Failure Modes and Effects Analysis to Treatment Planning System QA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mathew, D; Alaei, P

    2016-06-15

    Purpose: A small-scale implementation of Failure Modes and Effects Analysis (FMEA) for treatment planning system QA by utilizing methodology of AAPM TG-100 report. Methods: FMEA requires numerical values for severity (S), occurrence (O) and detectability (D) of each mode of failure. The product of these three values gives a risk priority number (RPN). We have implemented FMEA for the treatment planning system (TPS) QA for two clinics which use Pinnacle and Eclipse TPS. Quantitative monthly QA data dating back to 4 years for Pinnacle and 1 year for Eclipse have been used to determine values for severity (deviations from predeterminedmore » doses at points or volumes), and occurrence of such deviations. The TPS QA protocol includes a phantom containing solid water and lung- and bone-equivalent heterogeneities. Photon and electron plans have been evaluated in both systems. The dose values at multiple distinct points of interest (POI) within the solid water, lung, and bone-equivalent slabs, as well as mean doses to several volumes of interest (VOI), have been re-calculated monthly using the available algorithms. Results: The computed doses vary slightly month-over-month. There have been more significant deviations following software upgrades, especially if the upgrade involved re-modeling of the beams. TG-100 guidance and the data presented here suggest an occurrence (O) of 2 depending on the frequency of re-commissioning the beams, severity (S) of 3, and detectability (D) of 2, giving an RPN of 12. Conclusion: Computerized treatment planning systems could pose a risk due to dosimetric errors and suboptimal treatment plans. The FMEA analysis presented here suggests that TPS QA should immediately follow software upgrades, but does not need to be performed every month.« less

  13. Comparison of flow and gas washout characteristics between pressure control and high-frequency percussive ventilation using a test lung

    PubMed Central

    Dutta, Rabijit; Xing, Tao; Swanson, Craig; Heltborg, Jeff; Murdoch, Gordon K

    2018-01-01

    Objective A comparison between flow and gas washout data for high-frequency percussive ventilation (HFPV) and pressure control ventilation (PCV) under similar conditions is currently not available. This bench study aims to compare and describe the flow and gas washout behavior of HFPV and PCV in a newly designed experimental setup and establish a framework for future clinical and animal studies. Approach We studied gas washout behavior using a newly designed experimental setup that is motivated by the multi-breath nitrogen washout measurements. In this procedure, a test lung was filled with nitrogen gas before it was connected to a ventilator. Pressure, volume, and oxygen concentrations were recorded under different compliance and resistance conditions. PCV was compared with two settings of HFPV, namely, HFPV-High and HFPV-Low, to simulate the different variations in its clinical application. In the HFPV-Low mode, the peak pressures and drive pressures of HFPV and PCV are matched, whereas in the HFPV-High mode, the mean airway pressures (MAP) are matched. Main results HFPV-Low mode delivers smaller tidal volume (VT) as compared to PCV under all lung conditions, whereas HFPV-High delivers a larger VT. HFPV-High provides rapid washout as compared to PCV under all lung conditions. HFPV-Low takes a longer time to wash out nitrogen except at a low compliance, where it expedites washout at a smaller VT and MAP compared to PCV washout. Significance Various flow parameters for HFPV and PCV are mathematically defined. A shorter washout time at a small VT in low compliant test lungs for HFPV could be regarded as a hypothesis for lung protective ventilation for animal or human lungs. PMID:29369819

  14. Comparison of flow and gas washout characteristics between pressure control and high-frequency percussive ventilation using a test lung.

    PubMed

    Dutta, Rabijit; Xing, Tao; Swanson, Craig; Heltborg, Jeff; Murdoch, Gordon K

    2018-03-15

    A comparison between flow and gas washout data for high-frequency percussive ventilation (HFPV) and pressure control ventilation (PCV) under similar conditions is currently not available. This bench study aims to compare and describe the flow and gas washout behavior of HFPV and PCV in a newly designed experimental setup and establish a framework for future clinical and animal studies. We studied gas washout behavior using a newly designed experimental setup that is motivated by the multi-breath nitrogen washout measurements. In this procedure, a test lung was filled with nitrogen gas before it was connected to a ventilator. Pressure, volume, and oxygen concentrations were recorded under different compliance and resistance conditions. PCV was compared with two settings of HFPV, namely, HFPV-High and HFPV-Low, to simulate the different variations in its clinical application. In the HFPV-Low mode, the peak pressures and drive pressures of HFPV and PCV are matched, whereas in the HFPV-High mode, the mean airway pressures (MAP) are matched. HFPV-Low mode delivers smaller tidal volume (V T ) as compared to PCV under all lung conditions, whereas HFPV-High delivers a larger V T . HFPV-High provides rapid washout as compared to PCV under all lung conditions. HFPV-Low takes a longer time to wash out nitrogen except at a low compliance, where it expedites washout at a smaller V T and MAP compared to PCV washout. Various flow parameters for HFPV and PCV are mathematically defined. A shorter washout time at a small V T in low compliant test lungs for HFPV could be regarded as a hypothesis for lung protective ventilation for animal or human lungs.

  15. Measuring Blood Glucose Concentrations in Photometric Glucometers Requiring Very Small Sample Volumes.

    PubMed

    Demitri, Nevine; Zoubir, Abdelhak M

    2017-01-01

    Glucometers present an important self-monitoring tool for diabetes patients and, therefore, must exhibit high accuracy as well as good usability features. Based on an invasive photometric measurement principle that drastically reduces the volume of the blood sample needed from the patient, we present a framework that is capable of dealing with small blood samples, while maintaining the required accuracy. The framework consists of two major parts: 1) image segmentation; and 2) convergence detection. Step 1 is based on iterative mode-seeking methods to estimate the intensity value of the region of interest. We present several variations of these methods and give theoretical proofs of their convergence. Our approach is able to deal with changes in the number and position of clusters without any prior knowledge. Furthermore, we propose a method based on sparse approximation to decrease the computational load, while maintaining accuracy. Step 2 is achieved by employing temporal tracking and prediction, herewith decreasing the measurement time, and, thus, improving usability. Our framework is tested on several real datasets with different characteristics. We show that we are able to estimate the underlying glucose concentration from much smaller blood samples than is currently state of the art with sufficient accuracy according to the most recent ISO standards and reduce measurement time significantly compared to state-of-the-art methods.

  16. A generalized quantitative interpretation of dark-field contrast for highly concentrated microsphere suspensions

    PubMed Central

    Gkoumas, Spyridon; Villanueva-Perez, Pablo; Wang, Zhentian; Romano, Lucia; Abis, Matteo; Stampanoni, Marco

    2016-01-01

    In X-ray grating interferometry, dark-field contrast arises due to partial extinction of the detected interference fringes. This is also called visibility reduction and is attributed to small-angle scattering from unresolved structures in the imaged object. In recent years, analytical quantitative frameworks of dark-field contrast have been developed for highly diluted monodisperse microsphere suspensions with maximum 6% volume fraction. These frameworks assume that scattering particles are separated by large enough distances, which make any interparticle scattering interference negligible. In this paper, we start from the small-angle scattering intensity equation and, by linking Fourier and real-space, we introduce the structure factor and thus extend the analytical and experimental quantitative interpretation of dark-field contrast, for a range of suspensions with volume fractions reaching 40%. The structure factor accounts for interparticle scattering interference. Without introducing any additional fitting parameters, we successfully predict the experimental values measured at the TOMCAT beamline, Swiss Light Source. Finally, we apply this theoretical framework to an experiment probing a range of system correlation lengths by acquiring dark-field images at different energies. This proposed method has the potential to be applied in single-shot-mode using a polychromatic X-ray tube setup and a single-photon-counting energy-resolving detector. PMID:27734931

  17. Wave-induced response of a floating two-dimensional body with a moonpool

    PubMed Central

    Fredriksen, Arnt G.; Kristiansen, Trygve; Faltinsen, Odd M.

    2015-01-01

    Regular wave-induced behaviour of a floating stationary two-dimensional body with a moonpool is studied. The focus is on resonant piston-mode motion in the moonpool and rigid-body motions. Dedicated two-dimensional experiments have been performed. Two numerical hybrid methods, which have previously been applied to related problems, are further developed. Both numerical methods couple potential and viscous flow. The semi-nonlinear hybrid method uses linear free-surface and body-boundary conditions. The other one uses fully nonlinear free-surface and body-boundary conditions. The harmonic polynomial cell method solves the Laplace equation in the potential flow domain, while the finite volume method solves the Navier–Stokes equations in the viscous flow domain near the body. Results from the two codes are compared with the experimental data. The nonlinear hybrid method compares well with the data, while certain discrepancies are observed for the semi-nonlinear method. In particular, the roll motion is over-predicted by the semi-nonlinear hybrid method. Error sources in the semi-nonlinear hybrid method are discussed. The moonpool strongly affects heave motions in a frequency range around the piston-mode resonance frequency of the moonpool. No resonant water motions occur in the moonpool at the piston-mode resonance frequency. Instead large moonpool motions occur at a heave natural frequency associated with small damping near the piston-mode resonance frequency. PMID:25512594

  18. Feasibility of large volume tumor ablation using multiple-mode strategy with fast scanning method: A numerical study

    NASA Astrophysics Data System (ADS)

    Wu, Hao; Shen, Guofeng; Qiao, Shan; Chen, Yazhu

    2017-03-01

    Sonication with fast scanning method can generate homogeneous lesions without complex planning. But when the target region is large, switching focus too fast will reduce the heat accumulation, the margin of which may not ablated. Furthermore, high blood perfusion rate will reduce this maximum volume that can be ablated. Therefore, fast scanning method may not be applied to large volume tumor. To expand the therapy scope, this study combines the fast scan method with multiple mode strategy. Through simulation and experiment, the feasibility of this new strategy is evaluated and analyzed.

  19. High definition in vivo retinal volumetric video rate OCT at 0.6 Giga-voxels per second

    NASA Astrophysics Data System (ADS)

    Kolb, Jan Philip; Klein, Thomas; Wieser, Wolfgang; Draxinger, Wolfgang; Huber, Robert

    2015-07-01

    We present full volumetric high speed OCT imaging of the retina with multiple settings varying in volume size and volume rate. The volume size ranges from 255x255 A-scans to 160x40 A-scans with 450 samples per depth scan with volume rates varying between 20.8 V/s for the largest volumes to 195.2 V/s for the smallest. The system is based on a 1060nm Fourier domain mode locked (FDML) laser with 1.6MHz line rate. Scanning along the fast axis is performed with a 2.7 kHz or 4.3 kHz resonant scanner operated in bidirectional scanning mode, while a standard galvo scanner is used for the slow axis. The performance is analyzed with respect to various potential applications, like intraoperative OCT.

  20. Optical design of nanowire absorbers for wavelength selective photodetectors

    PubMed Central

    Mokkapati, S.; Saxena, D.; Tan, H. H.; Jagadish, C.

    2015-01-01

    We propose the optical design for the absorptive element of photodetectors to achieve wavelength selective photo response based on resonant guided modes supported in semiconductor nanowires. We show that the waveguiding properties of nanowires result in very high absorption efficiency that can be exploited to reduce the volume of active semiconductor compared to planar photodetectors, without compromising the photocurrent. We present a design based on a group of nanowires with varying diameter for multi-color photodetectors with small footprint. We discuss the effect of a dielectric shell around the nanowires on the absorption efficiency and present a simple approach to optimize the nanowire diameter-dielectric shell thickness for maximizing the absorption efficiency. PMID:26469227

  1. A field-deployable compound-specific isotope analyzer based on quantum cascade laser and hollow waveguide

    NASA Astrophysics Data System (ADS)

    Wu, Sheng; Deev, Andrei

    2013-01-01

    A field deployable Compound Specific Isotope Analyzer (CSIA) coupled with capillary chromatogrpahy based on Quantum Cascade (QC) lasers and Hollow Waveguide (HWG) with precision and chemical resolution matching mature Mass Spectroscopy has been achieved in our laboratory. The system could realize 0.3 per mil accuracy for 12C/13C for a Gas Chromatography (GC) peak lasting as short as 5 seconds with carbon molar concentration in the GC peak less than 0.5%. Spectroscopic advantages of HWG when working with QC lasers, i.e. single mode transmission, noiseless measurement and small sample volume, are compared with traditional free space and multipass spectroscopy methods.

  2. The two-dimensional hybrid surface plasma micro-cavity

    NASA Astrophysics Data System (ADS)

    Kai, Tong; Mei-yu, Wang; Fu-cheng, Wang; Jia, Guo

    2018-07-01

    A hybrid surface plasma micro-cavity structure with a defect cavity is formed based on the two-dimensional surface plasmon resonance photonic crystal waveguide structure. A cell defect is introduced in the centre of the photonic crystal layer to build the hybrid surface plasma micro-cavity structure. This work is numerical based on the finite-difference time-domain method. The photon energy is confined to the micro-cavity and the photon energy is strongest at the interface between the insulating layer and the metal layer. The micro-cavity structure has a very small mode volume of sub-wavelength scale in the 1550 nm communication band. The value of Q/V is up to 7132.08 λ/n-3.

  3. Nonlinear Fano-Resonant Dielectric Metasurfaces

    DOE PAGES

    Yang, Yuanmu; Wang, Wenyi; Boulesbaa, Abdelaziz; ...

    2015-10-26

    Strong nonlinear light matter interaction is highly sought-after for a variety of applications including lasing and all-optical light modulation. Recently, resonant plasmonic structures have been considered promising candidates for enhancing nonlinear optical processes due to their ability to greatly enhance the optical near-field; however, their small mode volumes prevent the inherently large nonlinear susceptibility of the metal from being efficiently exploited. We present an alternative approach that utilizes a Fano-resonant silicon metasurface. The metasurface results in strong near-field enhancement within the volume of the silicon resonator while minimizing two photon absorption. Here, we measure a third harmonic generation enhancement factormore » of 1.5 105 with respect to an unpatterned silicon film and an absolute conversion efficiency of 1.2 10 6 with a peak pump intensity of 3.2 GW cm 2. The enhanced nonlinearity, combined with a sharp linear transmittance spectrum, results in transmission modulation with a modulation depth of 36%. Finally, the modulation mechanism is studied by pump probe experiments« less

  4. Collective strong coupling with homogeneous Rabi frequencies using a 3D lumped element microwave resonator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Angerer, Andreas, E-mail: andreas.angerer@tuwien.ac.at; Astner, Thomas; Wirtitsch, Daniel

    We design and implement 3D-lumped element microwave cavities that spatially focus magnetic fields to a small mode volume. They allow coherent and uniform coupling to electron spins hosted by nitrogen vacancy centers in diamond. We achieve large homogeneous single spin coupling rates, with an enhancement of more than one order of magnitude compared to standard 3D cavities with a fundamental resonance at 3 GHz. Finite element simulations confirm that the magnetic field distribution is homogeneous throughout the entire sample volume, with a root mean square deviation of 1.54%. With a sample containing 10{sup 17} nitrogen vacancy electron spins, we achieve amore » collective coupling strength of Ω = 12 MHz, a cooperativity factor C = 27, and clearly enter the strong coupling regime. This allows to interface a macroscopic spin ensemble with microwave circuits, and the homogeneous Rabi frequency paves the way to manipulate the full ensemble population in a coherent way.« less

  5. Micro-machined resonator oscillator

    DOEpatents

    Koehler, Dale R.; Sniegowski, Jeffry J.; Bivens, Hugh M.; Wessendorf, Kurt O.

    1994-01-01

    A micro-miniature resonator-oscillator is disclosed. Due to the miniaturization of the resonator-oscillator, oscillation frequencies of one MHz and higher are utilized. A thickness-mode quartz resonator housed in a micro-machined silicon package and operated as a "telemetered sensor beacon" that is, a digital, self-powered, remote, parameter measuring-transmitter in the FM-band. The resonator design uses trapped energy principles and temperature dependence methodology through crystal orientation control, with operation in the 20-100 MHz range. High volume batch-processing manufacturing is utilized, with package and resonator assembly at the wafer level. Unique design features include squeeze-film damping for robust vibration and shock performance, capacitive coupling through micro-machined diaphragms allowing resonator excitation at the package exterior, circuit integration and extremely small (0.1 in. square) dimensioning. A family of micro-miniature sensor beacons is also disclosed with widespread applications as bio-medical sensors, vehicle status monitors and high-volume animal identification and health sensors. The sensor family allows measurement of temperatures, chemicals, acceleration and pressure. A microphone and clock realization is also available.

  6. Plasma density injection and flow during coaxial helicity injection in a tokamak

    NASA Astrophysics Data System (ADS)

    Hooper, E. B.

    2018-02-01

    Whole device, resistive MHD simulations of spheromaks and tokamaks have used a large diffusion coefficient that maintains a nearly constant density throughout the device. In the present work, helicity and plasma are coinjected into a low-density plasma in a tokamak with a small diffusion coefficient. As in previous simulations [Hooper et al., Phys. Plasmas 20, 092510 (2013)], a flux bubble is formed, which expands to fill the tokamak volume. The injected plasma is non-uniform inside the bubble. The flow pattern is analyzed; when the simulation is not axisymmetric, an n = 1 mode on the surface of the bubble generates leakage of plasma into the low-density volume. Closed flux is generated following injection, as in experiments and previous simulations. The result provides a more detailed physics analysis of the injection, including density non-uniformities in the plasma that may affect its use as a startup plasma [Raman et al., Phys. Rev. Lett. 97, 175002 (2006)].

  7. Reducing beam hardening effects and metal artefacts in spectral CT using Medipix3RX

    NASA Astrophysics Data System (ADS)

    Rajendran, K.; Walsh, M. F.; de Ruiter, N. J. A.; Chernoglazov, A. I.; Panta, R. K.; Butler, A. P. H.; Butler, P. H.; Bell, S. T.; Anderson, N. G.; Woodfield, T. B. F.; Tredinnick, S. J.; Healy, J. L.; Bateman, C. J.; Aamir, R.; Doesburg, R. M. N.; Renaud, P. F.; Gieseg, S. P.; Smithies, D. J.; Mohr, J. L.; Mandalika, V. B. H.; Opie, A. M. T.; Cook, N. J.; Ronaldson, J. P.; Nik, S. J.; Atharifard, A.; Clyne, M.; Bones, P. J.; Bartneck, C.; Grasset, R.; Schleich, N.; Billinghurst, M.

    2014-03-01

    This paper discusses methods for reducing beam hardening effects and metal artefacts using spectral x-ray information in biomaterial samples. A small-animal spectral scanner was operated in the 15 to 80 keV x-ray energy range for this study. We use the photon-processing features of a CdTe-Medipix3RX ASIC in charge summing mode to reduce beam hardening and associated artefacts. We present spectral data collected for metal alloy samples, its analysis using algebraic 3D reconstruction software and volume visualisation using a custom volume rendering software. The cupping effect and streak artefacts are quantified in the spectral datasets. The results show reduction in beam hardening effects and metal artefacts in the narrow high energy range acquired using the spectroscopic detector. A post-reconstruction comparison between CdTe-Medipix3RX and Si-Medipix3.1 is discussed. The raw data and processed data are made available (http://hdl.handle.net/10092/8851) for testing with other software routines.

  8. Childhood-Onset Asthma in Smokers. Association between CT Measures of Airway Size, Lung Function, and Chronic Airflow Obstruction

    PubMed Central

    Hardin, Megan E.; Come, Carolyn E.; San José Estépar, Raúl; Ross, James C.; Kurugol, Sila; Okajima, Yuka; Han, MeiLan K.; Kim, Victor; Ramsdell, Joe; Silverman, Edwin K.; Crapo, James D.; Lynch, David A.; Make, Barry; Barr, R. Graham; Hersh, Craig P.; Washko, George R.

    2014-01-01

    Rationale and Objectives: Asthma is associated with chronic airflow obstruction. Our goal was to assess the association of computed tomographic measures of airway wall volume and lumen volume with the FEV1 and chronic airflow obstruction in smokers with childhood-onset asthma. Methods: We analyzed clinical, lung function, and volumetric computed tomographic airway volume data from 7,266 smokers, including 590 with childhood-onset asthma. Small wall volume and small lumen volume of segmental airways were defined as measures 1 SD below the mean. We assessed the association between small wall volume, small lumen volume, FEV1, and chronic airflow obstruction (post-bronchodilator FEV1/FVC ratio < 0.7) using linear and logistic models. Measurements and Main Results: Compared with subjects without childhood-onset asthma, those with childhood-onset asthma had smaller wall volume and lumen volume (P < 0.0001) of segmental airways. Among subjects with childhood-onset asthma, those with the smallest wall volume and lumen volume had the lowest FEV1 and greatest odds of chronic airflow obstruction. A similar tendency was seen in those without childhood-onset asthma. When comparing these two groups, both small wall volume and small lumen volume were more strongly associated with FEV1 and chronic airflow obstruction among subjects with childhood-asthma in multivariate models. Conclusion: In smokers with childhood-onset asthma, smaller airways are associated with reduced lung function and chronic airflow obstruction. Clinical trial registered with www.clinicaltrials.gov (NCT00608764). PMID:25296268

  9. Childhood-onset asthma in smokers. association between CT measures of airway size, lung function, and chronic airflow obstruction.

    PubMed

    Diaz, Alejandro A; Hardin, Megan E; Come, Carolyn E; San José Estépar, Raúl; Ross, James C; Kurugol, Sila; Okajima, Yuka; Han, MeiLan K; Kim, Victor; Ramsdell, Joe; Silverman, Edwin K; Crapo, James D; Lynch, David A; Make, Barry; Barr, R Graham; Hersh, Craig P; Washko, George R

    2014-11-01

    Asthma is associated with chronic airflow obstruction. Our goal was to assess the association of computed tomographic measures of airway wall volume and lumen volume with the FEV1 and chronic airflow obstruction in smokers with childhood-onset asthma. We analyzed clinical, lung function, and volumetric computed tomographic airway volume data from 7,266 smokers, including 590 with childhood-onset asthma. Small wall volume and small lumen volume of segmental airways were defined as measures 1 SD below the mean. We assessed the association between small wall volume, small lumen volume, FEV1, and chronic airflow obstruction (post-bronchodilator FEV1/FVC ratio < 0.7) using linear and logistic models. Compared with subjects without childhood-onset asthma, those with childhood-onset asthma had smaller wall volume and lumen volume (P < 0.0001) of segmental airways. Among subjects with childhood-onset asthma, those with the smallest wall volume and lumen volume had the lowest FEV1 and greatest odds of chronic airflow obstruction. A similar tendency was seen in those without childhood-onset asthma. When comparing these two groups, both small wall volume and small lumen volume were more strongly associated with FEV1 and chronic airflow obstruction among subjects with childhood-asthma in multivariate models. In smokers with childhood-onset asthma, smaller airways are associated with reduced lung function and chronic airflow obstruction. Clinical trial registered with www.clinicaltrials.gov (NCT00608764).

  10. Rock Fracture Toughness Under Mode II Loading: A Theoretical Model Based on Local Strain Energy Density

    NASA Astrophysics Data System (ADS)

    Rashidi Moghaddam, M.; Ayatollahi, M. R.; Berto, F.

    2018-01-01

    The values of mode II fracture toughness reported in the literature for several rocks are studied theoretically by using a modified criterion based on strain energy density averaged over a control volume around the crack tip. The modified criterion takes into account the effect of T-stress in addition to the singular terms of stresses/strains. The experimental results are related to mode II fracture tests performed on the semicircular bend and Brazilian disk specimens. There are good agreements between theoretical predictions using the generalized averaged strain energy density criterion and the experimental results. The theoretical results reveal that the value of mode II fracture toughness is affected by the size of control volume around the crack tip and also the magnitude and sign of T-stress.

  11. Proton radiography for inline treatment planning and positioning verification of small animals.

    PubMed

    Müller, Johannes; Neubert, Christian; von Neubeck, Cläre; Baumann, Michael; Krause, Mechthild; Enghardt, Wolfgang; Bütof, Rebecca; Dietrich, Antje; Lühr, Armin

    2017-11-01

    As proton therapy becomes increasingly well established, there is a need for high-quality clinically relevant in vivo data to gain better insight into the radiobiological effects of proton irradiation on both healthy and tumor tissue. This requires the development of easily applicable setups that allow for efficient, fractionated, image-guided proton irradiation of small animals, the most widely used pre-clinical model. Here, a method is proposed to perform dual-energy proton radiography for inline positioning verification and treatment planning. Dual-energy proton radiography exploits the differential enhancement of object features in two successively measured two-dimensional (2D) dose distributions at two different proton energies. The two raw images show structures that are dominated by energy absorption (absorption mode) or scattering (scattering mode) of protons in the object, respectively. Data post-processing allowed for the separation of both signal contributions in the respective images. The images were evaluated regarding recognizable object details and feasibility of rigid registration to acquired planar X-ray scans. Robust, automated rigid registration of proton radiography and planar X-ray images in scattering mode could be reliably achieved with the animal bedding unit used as registration landmark. Distinguishable external and internal features of the imaged mouse included the outer body contour, the skull with substructures, the lung, abdominal structures and the hind legs. Image analysis based on the combined information of both imaging modes allowed image enhancement and calculation of 2D water-equivalent path length (WEPL) maps of the object along the beam direction. Fractionated irradiation of exposed target volumes (e.g., subcutaneous tumor model or brain) can be realized with the suggested method being used for daily positioning and range determination. Robust registration of X-ray and proton radiography images allows for the irradiation of tumor entities that require conventional computed tomography (CT)-based planning, such as orthotopic lung or brain tumors, similar to conventional patient treatment.

  12. Design and nonlinear modeling of a sensitive sensor for the measurement of flow in mice.

    PubMed

    Bou Jawde, Samer; Smith, Bradford J; Sonnenberg, Adam; Bates, Jason H T; Suki, Bela

    2018-06-07

    While many studies rely on flow and pressure measurements in small animal models of respiratory disease, such measurements can however be inaccurate and difficult to obtain. Thus, the goal of this study was to design and implement an easy to manufacture and accurate sensor capable of monitoring flow. We designed and 3-D printed a flowmeter and utilized parametric (resistance and inertance) and nonparametric (polynomial and Volterra series) system identification to characterize the device. The sensor was tested in a closed system for apparent flow using the common mode rejection ratio (CMRR). The sensor properly measured tidal volumes and respiratory rates in spontaneously breathing mice. The device was used to evaluate a ventilator's ability to deliver a prescribed volume before and after lung injury. The parametric and polynomial models provided a reasonable prediction of the independently measured flow (Coefficient of determination (Cv)=0.9591 and 0.9147 respectively), but the Volterra series of the 1st, 2nd, and 3rd order with a memory of six time points provided better fits (Cv=0.9775, 0.9787, and 0.9954, respectively). At and below the mouse breathing frequency (1-5 Hz), CMRR was higher than 40 dB. Following lung injury, the sensor revealed a significant drop in delivered tidal volume. We demonstrate that the application of nonparametric nonlinear Volterra series modeling in combination with 3-D printing technology allows the inexpensive and rapid fabrication of an accurate flow sensor for continuously measuring small flows in various physiological conditions. © 2018 Institute of Physics and Engineering in Medicine.

  13. Emptying patterns of the lung studied by multiple-breath N2 washout

    NASA Technical Reports Server (NTRS)

    Lewis, S. M.

    1978-01-01

    Changes in the nitrogen concentration seen during the single-breath nitrogen washout reflect changes in relative flow (ventilation) from units with differing ventilation/volume ratios. The multiple-breath washout provides sufficient data on ventilation for units with varying ventilation/volume ratios to be plotted as a function of the volume expired. Flow from the dead space may also be determined. In young normals the emptying patterns are narrow and unimodal throughout the alveolar plateau with little or no flow from the dead space at the end of the breath. Older normals show more flow from the dead space, particularly toward the end of the breath, and some show a high ventilation/volume ratio mode early in the breath. Patients with obstructive lung disease have a high flow from the dead space which is present throughout the breath. A well ventilated mode at the end of the breath is seen in some obstructed subjects. Patients with cystic fibrosis showed a poorly ventilated mode appearing at the end of the breath as well as a very high dead space.

  14. Predicting oropharyngeal tumor volume throughout the course of radiation therapy from pretreatment computed tomography data using general linear models.

    PubMed

    Yock, Adam D; Rao, Arvind; Dong, Lei; Beadle, Beth M; Garden, Adam S; Kudchadker, Rajat J; Court, Laurence E

    2014-05-01

    The purpose of this work was to develop and evaluate the accuracy of several predictive models of variation in tumor volume throughout the course of radiation therapy. Nineteen patients with oropharyngeal cancers were imaged daily with CT-on-rails for image-guided alignment per an institutional protocol. The daily volumes of 35 tumors in these 19 patients were determined and used to generate (1) a linear model in which tumor volume changed at a constant rate, (2) a general linear model that utilized the power fit relationship between the daily and initial tumor volumes, and (3) a functional general linear model that identified and exploited the primary modes of variation between time series describing the changing tumor volumes. Primary and nodal tumor volumes were examined separately. The accuracy of these models in predicting daily tumor volumes were compared with those of static and linear reference models using leave-one-out cross-validation. In predicting the daily volume of primary tumors, the general linear model and the functional general linear model were more accurate than the static reference model by 9.9% (range: -11.6%-23.8%) and 14.6% (range: -7.3%-27.5%), respectively, and were more accurate than the linear reference model by 14.2% (range: -6.8%-40.3%) and 13.1% (range: -1.5%-52.5%), respectively. In predicting the daily volume of nodal tumors, only the 14.4% (range: -11.1%-20.5%) improvement in accuracy of the functional general linear model compared to the static reference model was statistically significant. A general linear model and a functional general linear model trained on data from a small population of patients can predict the primary tumor volume throughout the course of radiation therapy with greater accuracy than standard reference models. These more accurate models may increase the prognostic value of information about the tumor garnered from pretreatment computed tomography images and facilitate improved treatment management.

  15. 40 CFR 1051.635 - What provisions apply to new manufacturers that are small businesses?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Act. For example, we may place sales limits on companies that we designate to be small-volume....201) that manufactures recreational vehicles, but does not otherwise qualify for the small-volume manufacturer provisions of this part, you may ask us to designate you to be a small-volume manufacturer. You...

  16. Column-integrated aerosol optical properties of coarse- and fine-mode particles over the Pearl River Delta region in China.

    PubMed

    Mai, B; Deng, X; Xia, X; Che, H; Guo, J; Liu, X; Zhu, J; Ling, C

    2018-05-01

    The sun-photometer data from 2011 to 2013 at Panyu site (Panyu) and from 2007 to 2013 at Dongguan site (Dg) in the Pearl River Delta region, were used for the retrieving of the aerosol optical depth (AOD), single scattering albedo (SSA), Ångström exponent (AE) and volume size distribution of coarse- and fine-mode particles. The coarse-mode particles presented low AOD (ranging from 0.05±0.03 to 0.08±0.05) but a strong absorption property (SSA ranged from 0.70±0.03 to 0.90±0.02) for the wavelengths between 440 and 1020nm. However, these coarse particles accounted for <10% of the total particles. The AOD of fine particles (AODf) was over 3 times as large as that of coarse particles (AODc). The fine particles SSA (SSAf) generally decreased as a function of wavelength, and the relatively lower SSAf value in summer was likely to be due to the stronger solar radiation and higher temperature. More than 70% of the aerosols at Panyu site were dominated by fine-mode absorbing particles, whereas about 70% of the particles at Dg site were attributed to fine-mode scattering particles. The differences of the aerosol optical properties between the two sites are likely associated with local emissions of the light-absorbing carbonaceous aerosols and the scattering aerosols (e.g., sulfate and nitrate particles) caused by the gas-phase oxidation of gaseous precursors (e.g., SO 2 and NO 2 ). The size distribution exhibited bimodal structures in which the accumulation mode was predominant. The fine-mode volume showed positive dependence on AOD (500nm), and the growth of peak value of the fine-mode volume was higher than that of the coarse volume. Both the AOD and SSA increased with increasing relative humidity (RH), while the AE decreased with increasing RH. These correlations imply that the aerosol properties are greatly modified by condensation growth. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. 40 CFR 80.1622 - Approval for small refiner and small volume refinery status.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... appropriate data to correct the record when the company submits its application. (ii) Foreign small refiners... 40 Protection of Environment 17 2014-07-01 2014-07-01 false Approval for small refiner and small... Approval for small refiner and small volume refinery status. (a) Applications for small refiner or small...

  18. Ultra-compact air-mode photonic crystal nanobeam cavity integrated with bandstop filter for refractive index sensing.

    PubMed

    Sun, Fujun; Fu, Zhongyuan; Wang, Chunhong; Ding, Zhaoxiang; Wang, Chao; Tian, Huiping

    2017-05-20

    We propose and investigate an ultra-compact air-mode photonic crystal nanobeam cavity (PCNC) with an ultra-high quality factor-to-mode volume ratio (Q/V) by quadratically tapering the lattice space of the rectangular holes from the center to both ends while other parameters remain unchanged. By using the three-dimensional finite-difference time-domain method, an optimized geometry yields a Q of 7.2×10 6 and a V∼1.095(λ/n Si ) 3 in simulations, resulting in an ultra-high Q/V ratio of about 6.5×10 6 (λ/n Si ) -3 . When the number of holes on either side is 8, the cavity possesses a high sensitivity of 252 nm/RIU (refractive index unit), a high calculated Q-factor of 1.27×10 5 , and an ultra-small effective V of ∼0.758(λ/n Si ) 3 at the fundamental resonant wavelength of 1521.74 nm. Particularly, the footprint is only about 8×0.7  μm 2 . However, inevitably our proposed PCNC has several higher-order resonant modes in the transmission spectrum, which makes the PCNC difficult to be used for multiplexed sensing. Thus, a well-designed bandstop filter with weak sidelobes and broad bandwidth based on a photonic crystal nanobeam waveguide is created to connect with the PCNC to filter out the high-order modes. Therefore, the integrated structure presented in this work is promising for building ultra-compact lab-on-chip sensor arrays with high density and parallel-multiplexing capability.

  19. Ozil IP torsional mode versus combined torsional/longitudinal microcoaxial phacoemulsification.

    PubMed

    Helvacioglu, Firat; Tunc, Zeki; Yeter, Celal; Oguzhan, Hasan; Sencan, Sadik

    2012-01-01

    To compare the safety and efficacy of microcoaxial phacoemulsification surgeries performed with the Ozil Intelligent Phaco (IP) torsional mode and combined torsional/longitudinal ultrasound (US) mode using the Infiniti Vision System (Alcon Laboratories). In this prospective randomized comparative study, 60 eyes were assigned to 2.2-mm microcoaxial phacoemulsification using the Ozil IP torsional mode (group 1) or combined torsional/longitudinal US mode (group 2). The primary outcome measures were US time (UST), cumulative dissipated energy (CDE), longitudinal and torsional ultrasound amplitudes, mean operation time, mean volume of balanced salt solution (BSS) used, and surgical complications. Both groups included 30 eyes. Mean UST, CDE, and longitudinal and torsional ultrasound amplitudes in group 1 were 1 minute 15±34.33 seconds, 8.74±5.64, 0.43±0.74, and 25.56±8.56, respectively, and these parameters in group 2 were 1 minute 40±51.44 seconds, 9.28±5.99, 3.64±1.55, and 3.71±1.34, respectively. UST and longitudinal amplitudes were found to be significantly low in group 1 (p<0.001, p<0.001), whereas torsional amplitude was found to be significantly high in this group (p=0.001). Mean volumes of BSS used in groups 1 and 2 were 63.30±18.00 cc and 84.50±28.65 cc, respectively (p=0.001). The Ozil IP torsional mode may provide more effective lens removal than the combined torsional/longitudinal US mode with a lower UST and volume of BSS used.

  20. High-frequency strontium vapor laser for biomedical applications

    NASA Astrophysics Data System (ADS)

    Hvorostovsky, A.; Kolmakov, E.; Kudashev, I.; Redka, D.; Kancer, A.; Kustikova, M.; Bykovskaya, E.; Mayurova, A.; Stupnikov, A.; Ruzankina, J.; Tsvetkov, K.; Lukyanov, N.; Paklinov, N.

    2018-02-01

    Sr-laser with high pulse repetition rate and high peak radiation power is a unique tool for studying rapidly occurring processes in time (plasma diagnostics, photoablation, etc.). In addition, the study of the frequency characteristics of the active medium of the laser helps to reveal the physics of the formation of an inverse medium in metal vapor lasers. In this paper, an experimental study of an Sr-laser with an active volume of 5.8 cm3 in the pulse repetition frequency range from 25 to 200 kHz is carried out, and a comparison with the frequency characteristics of media with large active volumes is given. We considered the frequency characteristics of the active medium in two modes: at a constant energy in the excitation pulse CU2 / 2 and at a constant average power consumed by the rectifier. In the presented work with a small-volume GRT using the TASITR-5/12 TASITRON switch, a laser was generated for Pairs of strontium at a CSF of 200 kHz. The behavior of the characteristics of the generation lines of 6.456 μm, 1 μm, and 3 μm at increased repetition frequencies is considered. Using the example of large-volume GRT, it is shown that tubes with a large active volume increase their energy characteristics with the growth of the CSF. The possibility of laser operation at pulse repetition rates above 200 kHz is shown.

  1. Normal modes of a small gamelan gong.

    PubMed

    Perrin, Robert; Elford, Daniel P; Chalmers, Luke; Swallowe, Gerry M; Moore, Thomas R; Hamdan, Sinin; Halkon, Benjamin J

    2014-10-01

    Studies have been made of the normal modes of a 20.7 cm diameter steel gamelan gong. A finite-element model has been constructed and its predictions for normal modes compared with experimental results obtained using electronic speckle pattern interferometry. Agreement was reasonable in view of the lack of precision in the manufacture of the instrument. The results agree with expectations for an axially symmetric system subject to small symmetry breaking. The extent to which the results obey Chladni's law is discussed. Comparison with vibrational and acoustical spectra enabled the identification of the small number of modes responsible for the sound output when played normally. Evidence of non-linear behavior was found, mainly in the form of subharmonics of true modes. Experiments using scanning laser Doppler vibrometry gave satisfactory agreement with the other methods.

  2. An estimation of vehicle kilometer traveled and on-road emissions using the traffic volume and travel speed on road links in Incheon City.

    PubMed

    Jung, Sungwoon; Kim, Jounghwa; Kim, Jeongsoo; Hong, Dahee; Park, Dongjoo

    2017-04-01

    The objective of this study is to estimate the vehicle kilometer traveled (VKT) and on-road emissions using the traffic volume in urban. We estimated two VKT; one is based on registered vehicles and the other is based on traffic volumes. VKT for registered vehicles was 2.11 times greater than that of the applied traffic volumes because each VKT estimation method is different. Therefore, we had to define the inner VKT is moved VKT inner in urban to compare two values. Also, we focused on freight modes because these are discharged much air pollutant emissions. From analysis results, we found middle and large trucks registered in other regions traveled to target city in order to carry freight, target city has included many industrial and logistics areas. Freight is transferred through the harbors, large logistics centers, or via locations before being moved to the final destination. During this process, most freight is moved by middle and large trucks, and trailers rather than small trucks for freight import and export. Therefore, these trucks from other areas are inflow more than registered vehicles. Most emissions from diesel trucks had been overestimated in comparison to VKT from applied traffic volumes in target city. From these findings, VKT is essential based on traffic volume and travel speed on road links in order to estimate accurately the emissions of diesel trucks in target city. Our findings support the estimation of the effect of on-road emissions on urban air quality in Korea. Copyright © 2016. Published by Elsevier B.V.

  3. Automated Transmission-Mode Scanning Electron Microscopy (tSEM) for Large Volume Analysis at Nanoscale Resolution

    PubMed Central

    Kuwajima, Masaaki; Mendenhall, John M.; Lindsey, Laurence F.; Harris, Kristen M.

    2013-01-01

    Transmission-mode scanning electron microscopy (tSEM) on a field emission SEM platform was developed for efficient and cost-effective imaging of circuit-scale volumes from brain at nanoscale resolution. Image area was maximized while optimizing the resolution and dynamic range necessary for discriminating key subcellular structures, such as small axonal, dendritic and glial processes, synapses, smooth endoplasmic reticulum, vesicles, microtubules, polyribosomes, and endosomes which are critical for neuronal function. Individual image fields from the tSEM system were up to 4,295 µm2 (65.54 µm per side) at 2 nm pixel size, contrasting with image fields from a modern transmission electron microscope (TEM) system, which were only 66.59 µm2 (8.160 µm per side) at the same pixel size. The tSEM produced outstanding images and had reduced distortion and drift relative to TEM. Automated stage and scan control in tSEM easily provided unattended serial section imaging and montaging. Lens and scan properties on both TEM and SEM platforms revealed no significant nonlinear distortions within a central field of ∼100 µm2 and produced near-perfect image registration across serial sections using the computational elastic alignment tool in Fiji/TrakEM2 software, and reliable geometric measurements from RECONSTRUCT™ or Fiji/TrakEM2 software. Axial resolution limits the analysis of small structures contained within a section (∼45 nm). Since this new tSEM is non-destructive, objects within a section can be explored at finer axial resolution in TEM tomography with current methods. Future development of tSEM tomography promises thinner axial resolution producing nearly isotropic voxels and should provide within-section analyses of structures without changing platforms. Brain was the test system given our interest in synaptic connectivity and plasticity; however, the new tSEM system is readily applicable to other biological systems. PMID:23555711

  4. InGaAsP/InP-air-aperture microcavities for single-photon sources at 1.55-μm telecommunication band

    NASA Astrophysics Data System (ADS)

    Guo, Sijie; Zheng, Yanzhen; Weng, Zhuo; Yao, Haicheng; Ju, Yuhao; Zhang, Lei; Ren, Zhilei; Gao, Ruoyao; Wang, Zhiming M.; Song, Hai-Zhi

    2016-11-01

    InGaAsP/InP-air-aperture micropillar cavities are proposed to serve as 1.55-μm single photon sources, which are indispensable in silica-fiber based quantum information processing. Owing to air-apertures introduced to InP layers, and adiabatically tapered distributed Bragg-reflector structures used in the central cavity layers, the pillar diameters can be less than 1 μm, achieving mode volume as small as (λ/n)3, and the quality factors are more than 104 - 105, sufficient to increase the quantum dot emission rate for 100 times and create strong coupling between the optical mode and the 1.55- μm InAs/InP quantum dot emitter. The mode wavelengths and quality factors are found weakly changing with the cavity size and the deviation from the ideal shape, indicating the robustness against the imperfection of the fabrication technique. The fabrication, simply epitaxial growth, dry and chemical etching, is a damage-free and monolithic process, which is advantageous over previous hybrid cavities. The above properties satisfy the requirements of efficient, photonindistinguishable and coherent 1.55-μm quantum dot single photon sources, so the proposed InGaAsP/InP-air-aperture micropillar cavities are prospective candidates for quantum information devices at telecommunication band.

  5. Application of the precipitation-runoff modeling system to the Ah- shi-sle-pah Wash watershed, San Juan County, New Mexico

    USGS Publications Warehouse

    Hejl, H.R.

    1989-01-01

    The precipitation-runoff modeling system was applied to the 8.21 sq-mi drainage area of the Ah-shi-sle-pah Wash watershed in northwestern New Mexico. The calibration periods were May to September of 1981 and 1982, and the verification period was May to September 1983. Twelve storms were available for calibration and 8 storms were available for verification. For calibration A (hydraulic conductivity estimated from onsite data and other storm-mode parameters optimized), the computed standard error of estimate was 50% for runoff volumes and 72% of peak discharges. Calibration B included hydraulic conductivity in the optimization, which reduced the standard error of estimate to 28 % for runoff volumes and 50% for peak discharges. Optimized values for hydraulic conductivity resulted in reductions from 1.00 to 0.26 in/h and 0.20 to 0.03 in/h for the 2 general soils groups in the calibrations. Simulated runoff volumes using 7 of 8 storms occurring during the verification period had a standard error of estimate of 40% for verification A and 38% for verification B. Simulated peak discharge had a standard error of estimate of 120% for verification A and 56% for verification B. Including the eighth storm which had a relatively small magnitude in the verification analysis more than doubled the standard error of estimating volumes and peaks. (USGS)

  6. [Lung protective ventilation. Ventilatory modes and ventilator parameters].

    PubMed

    Schädler, Dirk; Weiler, Norbert

    2008-06-01

    Mechanical ventilation has a considerable potential for injuring the lung tissue. Therefore, attention has to be paid to the proper choice of ventilatory mode and settings to secure lung-protective ventilation whenever possible. Such ventilator strategy should account for low tidal volume ventilation (6 ml/kg PBW), limited plateau pressure (30 to 35 cm H2O) and positive end-expiratory pressure (PEEP). It is unclear whether pressure controlled or volume controlled ventilation with square flow profile is beneficial. The adjustment of inspiration and expiration time should consider the actual breathing mechanics and anticipate the generation of intrinsic PEEP. Ventilatory modes with the possibility of supporting spontaneous breathing should be used as soon as possible.

  7. Volume versus wiring transmission in the brain: a new theoretical frame for neuropsychopharmacology.

    PubMed

    Agnati, L F; Bjelke, B; Fuxe, K

    1995-01-01

    A volume transmission mode of communication in brain was implicit already in the early work of Golgi, who postulated the existence of electrical signals in the extracellular fluid (ECF) based on Volta's "wet conductor" made by solutions. The term volume transmission is taken from the term volume conduction describing the flow of ionic currents in the ECF as a basis for the electrocorticogram. The slow VT mode includes also chemical signals and is opposed to the fast synaptic (wiring) transmission. Every neuron may function in a dual mode, the synaptic and the volume transmission mode, when considering the autocrine and synaptic classes of communication. The paracrine- and neuroendocrine-like classes only involve the VT mode in the latter case including the CSF as a route. The chemical signals for VT are the neuropeptides, but also the classical transmitters, the monoamines, acetylcholine, GABA, and glutamate can participate, when they operate via slow, high affinity G protein coupled receptors. Ions such as K+, Ca++, and H+ also function as VT signals. The hypothesis is also introduced that CO2 can act as a multifacit long-distance VT and WT regulator besides being part of the CO2/HCO3 buffer. CO2 via regulating NMDA receptor sensitivity can also regulate NO formation, which represents a paracrine and fast VT signal. The therapy of CNS disorders is also discussed in the frame of the wiring and VT concept. Two therapeutical approaches can therefore be developed, one based on increasing WT and one based on increasing VT. In contrast to the WT therapy, which must preserve the electrotemporal code, the VT therapy can operate also with postsynaptic agonists. Therefore, a therapeutic effect with such a drug indicates that the deficiency in the communication process operates via VT. In view of the lack of very effective negative feedbacks in VT vs. WT, VT therapy may produce less tolerance and drug dependency.

  8. Modes of mechanical ventilation for the operating room.

    PubMed

    Ball, Lorenzo; Dameri, Maddalena; Pelosi, Paolo

    2015-09-01

    Most patients undergoing surgical procedures need to be mechanically ventilated, because of the impact of several drugs administered at induction and during maintenance of general anaesthesia on respiratory function. Optimization of intraoperative mechanical ventilation can reduce the incidence of post-operative pulmonary complications and improve the patient's outcome. Preoxygenation at induction of general anaesthesia prolongs the time window for safe intubation, reducing the risk of hypoxia and overweighs the potential risk of reabsorption atelectasis. Non-invasive positive pressure ventilation delivered through different interfaces should be considered at the induction of anaesthesia morbidly obese patients. Anaesthesia ventilators are becoming increasingly sophisticated, integrating many functions that were once exclusive to intensive care. Modern anaesthesia machines provide high performances in delivering the desired volumes and pressures accurately and precisely, including assisted ventilation modes. Therefore, the physicians should be familiar with the potential and pitfalls of the most commonly used intraoperative ventilation modes: volume-controlled, pressure-controlled, dual-controlled and assisted ventilation. Although there is no clear evidence to support the advantage of any one of these ventilation modes over the others, protective mechanical ventilation with low tidal volume and low levels of positive end-expiratory pressure (PEEP) should be considered in patients undergoing surgery. The target tidal volume should be calculated based on the predicted or ideal body weight rather than on the actual body weight. To optimize ventilation monitoring, anaesthesia machines should include end-inspiratory and end-expiratory pause as well as flow-volume loop curves. The routine administration of high PEEP levels should be avoided, as this may lead to haemodynamic impairment and fluid overload. Higher PEEP might be considered during surgery longer than 3 h, laparoscopy in the Trendelenburg position and in patients with body mass index >35 kg/m(2). Large randomized trials are warranted to identify subgroups of patients and the type of surgery that can potentially benefit from specific ventilation modes or ventilation settings. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. An Inset CT Specimen for Evaluating Fracture in Small Samples of Material

    PubMed Central

    Yahyazadehfar, M.; Nazari, A.; Kruzic, J.J.; Quinn, G.D.; Arola, D.

    2013-01-01

    In evaluations on the fracture behavior of hard tissues and many biomaterials, the volume of material available to study is not always sufficient to apply a standard method of practice. In the present study an inset Compact Tension (inset CT) specimen is described, which uses a small cube of material (approximately 2×2×2 mm3) that is molded within a secondary material to form the compact tension geometry. A generalized equation describing the Mode I stress intensity was developed for the specimen using the solutions from a finite element model that was defined over permissible crack lengths, variations in specimen geometry, and a range in elastic properties of the inset and mold materials. A validation of the generalized equation was performed using estimates for the fracture toughness of a commercial dental composite via the “inset CT” specimen and the standard geometry defined by ASTM E399. Results showed that the average fracture toughness obtained from the new specimen (1.23 ± 0.02 MPa•m0.5) was within 2% of that from the standard. Applications of the inset CT specimen are presented for experimental evaluations on the crack growth resistance of dental enamel and root dentin, including their fracture resistance curves. Potential errors in adopting this specimen are then discussed, including the effects of debonding between the inset and molding material on the estimated stress intensity distribution. Results of the investigation show that the inset CT specimen offers a viable approach for studying the fracture behavior of small volumes of structural materials. PMID:24268892

  10. Advantages of semiconductor CZT for medical imaging

    NASA Astrophysics Data System (ADS)

    Wagenaar, Douglas J.; Parnham, Kevin; Sundal, Bjorn; Maehlum, Gunnar; Chowdhury, Samir; Meier, Dirk; Vandehei, Thor; Szawlowski, Marek; Patt, Bradley E.

    2007-09-01

    Cadmium zinc telluride (CdZnTe, or CZT) is a room-temperature semiconductor radiation detector that has been developed in recent years for a variety of applications. CZT has been investigated for many potential uses in medical imaging, especially in the field of single photon emission computed tomography (SPECT). CZT can also be used in positron emission tomography (PET) as well as photon-counting and integration-mode x-ray radiography and computed tomography (CT). The principal advantages of CZT are 1) direct conversion of x-ray or gamma-ray energy into electron-hole pairs; 2) energy resolution; 3) high spatial resolution and hence high space-bandwidth product; 4) room temperature operation, stable performance, high density, and small volume; 5) depth-of-interaction (DOI) available through signal processing. These advantages will be described in detail with examples from our own CZT systems. The ability to operate at room temperature, combined with DOI and very small pixels, make the use of multiple, stationary CZT "mini-gamma cameras" a realistic alternative to today's large Anger-type cameras that require motion to obtain tomographic sampling. The compatibility of CZT with Magnetic Resonance Imaging (MRI)-fields is demonstrated for a new type of multi-modality medical imaging, namely SPECT/MRI. For pre-clinical (i.e., laboratory animal) imaging, the advantages of CZT lie in spatial and energy resolution, small volume, automated quality control, and the potential for DOI for parallax removal in pinhole imaging. For clinical imaging, the imaging of radiographically dense breasts with CZT enables scatter rejection and hence improved contrast. Examples of clinical breast images with a dual-head CZT system are shown.

  11. Volume and surface area size distribution, water mass and model fitting of GCE/CASE/WATOX marine aerosols

    NASA Astrophysics Data System (ADS)

    Kim, Y.; Sievering, H.; Boatman, J.

    1990-06-01

    As a part of the Global Change Expedition/Coordinated Air-Sea Experiment/Western Atlantic Ocean Experiment (GCE/CASE/WATOX), size distributions of marine aerosols were measured at two altitudes of about 2750 and 150 m above sea level (asl) over the size range 0.1 ˜ 32 μm. Lognormal fitting was applied to the corrected aerosol size spectra to determine the volume and surface area size distributions of the CASE-WATOX marine aerosols. Each aerosol size distribution was fitted with three lognormal distributions representing fine-, large-, and giant-particle modes. Water volume fraction and dry particle size of each aerosol size distribution were also calculated using empirical formulas for particle size as a function of relative humidity and particle type. Because of the increased influence from anthropogenic sources in the continental United States, higher aerosol volume concentrations were observed in the fine-particle mode near-shore off the east coast; 2.11 and 3.63 μm3 cm-3 for free troposphere (FT) and marine boundary layer (MBL), compared with the open-sea Bermuda area values; 0.13 and 0.74 μm3 cm-3 for FT and MBL. The large-particle mode exhibits the least variations in volume distributions between the east coast and open-sea Bermuda area, having a volume geometric median diameter (VGMD) between 1.4 and 1.6 μm and a geometric standard deviation between 1.57 and 1.68. For the giant-particle mode, larger VGMD and volume concentrations were observed for marine aerosols nearshore off the east coast than in the open-sea Bermuda area because of higher relative humidity and higher surface wind speed conditions. Wet VGMD and aerosol water volume concentrations at 15 m asl ship level were determined by extrapolating from those obtained by analysis of the CASE-WATOX aircraft aerosol data. Abundance of aerosol water in the MBL serves as an important pathway for heterogeneous conversion of SO2 in sea salt aerosol particles.

  12. Simultaneous laser excitation of backward volume and perpendicular standing spin waves in full-Heusler Co2FeAl0.5Si0.5 films

    PubMed Central

    Chen, Zhifeng; Yan, Yong; Li, Shufa; Xu, Xiaoguang; Jiang, Yong; Lai, Tianshu

    2017-01-01

    Spin-wave dynamics in full-Heusler Co2FeAl0.5Si0.5 films are studied using all-optical pump-probe magneto-optical polar Kerr spectroscopy. Backward volume magnetostatic spin-wave (BVMSW) mode is observed in films with thickness ranging from 20 to 100 nm besides perpendicular standing spin-wave (PSSW) mode, and found to be excited more efficiently than the PSSW mode. The field dependence of the effective Gilbert damping parameter appears especial extrinsic origin. The relationship between the lifetime and the group velocity of BVMSW mode is revealed. The frequency of BVMSW mode does not obviously depend on the film thickness, but the lifetime and the effective damping appear to do so. The simultaneous excitation of BVMSW and PSSW in Heusler alloy films as well as the characterization of their dynamic behaviors may be of interest for magnonic and spintronic applications. PMID:28195160

  13. Wave-induced response of a floating two-dimensional body with a moonpool.

    PubMed

    Fredriksen, Arnt G; Kristiansen, Trygve; Faltinsen, Odd M

    2015-01-28

    Regular wave-induced behaviour of a floating stationary two-dimensional body with a moonpool is studied. The focus is on resonant piston-mode motion in the moonpool and rigid-body motions. Dedicated two-dimensional experiments have been performed. Two numerical hybrid methods, which have previously been applied to related problems, are further developed. Both numerical methods couple potential and viscous flow. The semi-nonlinear hybrid method uses linear free-surface and body-boundary conditions. The other one uses fully nonlinear free-surface and body-boundary conditions. The harmonic polynomial cell method solves the Laplace equation in the potential flow domain, while the finite volume method solves the Navier-Stokes equations in the viscous flow domain near the body. Results from the two codes are compared with the experimental data. The nonlinear hybrid method compares well with the data, while certain discrepancies are observed for the semi-nonlinear method. In particular, the roll motion is over-predicted by the semi-nonlinear hybrid method. Error sources in the semi-nonlinear hybrid method are discussed. The moonpool strongly affects heave motions in a frequency range around the piston-mode resonance frequency of the moonpool. No resonant water motions occur in the moonpool at the piston-mode resonance frequency. Instead large moonpool motions occur at a heave natural frequency associated with small damping near the piston-mode resonance frequency. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  14. Cavity magnon polaritons with lithium ferrite and three-dimensional microwave resonators at millikelvin temperatures

    NASA Astrophysics Data System (ADS)

    Goryachev, Maxim; Watt, Stuart; Bourhill, Jeremy; Kostylev, Mikhail; Tobar, Michael E.

    2018-04-01

    Single crystal lithium ferrite (LiFe) spheres of sub-mm dimension are examined at mK temperatures, microwave frequencies, and variable dc magnetic field, for use in hybrid quantum systems and condensed matter and fundamental physics experiments. Strong coupling regimes of the photon-magnon interaction (cavity magnon polariton quasiparticles) were observed with coupling strength of up to 250 MHz at 9.5 GHz (2.6%) with magnon linewidths of order 4 MHz (with potential improvement to sub-MHz values). We show that the photon-magnon coupling can be significantly improved and exceed that of the widely used yttrium iron garnet crystal, due to the small unit cell of LiFe, allowing twice the spins per unit volume. Magnon mode softening was observed at low dc fields and, combined with the normal Zeeman effect, creates magnon spin-wave modes that are insensitive to first-order magnetic-field fluctuations. This effect is observed in the Kittel mode at 5.5 GHz (and another higher order mode at 6.5 GHz) with a dc magnetic field close to 0.19 tesla. We show that if the cavity is tuned close to this frequency, the magnon polariton particles exhibit an enhanced range of strong coupling and insensitivity to magnetic field fluctuations with both first-order and second-order insensitivity to magnetic field as a function of frequency (double magic point clock transition), which could potentially be exploited in cavity QED experiments.

  15. Instabilities in rapid directional solidification under weak flow

    NASA Astrophysics Data System (ADS)

    Kowal, Katarzyna N.; Davis, Stephen H.; Voorhees, Peter W.

    2017-12-01

    We examine a rapidly solidifying binary alloy under directional solidification with nonequilibrium interfacial thermodynamics viz. the segregation coefficient and the liquidus slope are speed dependent and attachment-kinetic effects are present. Both of these effects alone give rise to (steady) cellular instabilities, mode S , and a pulsatile instability, mode P . We examine how weak imposed boundary-layer flow of magnitude |V | affects these instabilities. For small |V | , mode S becomes a traveling and the flow stabilizes (destabilizes) the interface for small (large) surface energies. For small |V | , mode P has a critical wave number that shifts from zero to nonzero giving spatial structure. The flow promotes this instability and the frequencies of the complex conjugate pairs each increase (decrease) with flow for large (small) wave numbers. These results are obtained by regular perturbation theory in powers of V far from the point where the neutral curves cross, but requires a modified expansion in powers of V1 /3 near the crossing. A uniform composite expansion is then obtained valid for all small |V | .

  16. The Shock and Vibration Digest. Volume 12, Number 11,

    DTIC Science & Technology

    1980-11-01

    AD-A092 384 NAVAL RESEARCH LAB WASHINGTON DC SHOCK AND VIBRATION--ETC F/S 20/11 THE SHOCK AND VIBRATIO DIG 1 EST . VOLUME 12 . NUMBER I1.IU) NOV B0 J1...sections. he compared his results with ones obtained previously [ 12 , 14]. A significant number of studies 110, 15, 21-41] have involved the vibrations of...frequencies and mode shapes of the first 12 modes numerical results [4, 12 , 16] and beam results. Ro- of a cantilevered cylindrical shell having a/b

  17. Exercise Mode Moderates the Relationship Between Mobility and Basal Ganglia Volume in Healthy Older Adults

    PubMed Central

    Nagamatsu, Lindsay S.; Weinstein, Andrea M.; Erickson, Kirk I.; Fanning, Jason; Awick, Elizabeth A.; Kramer, Arthur F.; McAuley, Edward

    2015-01-01

    Background Identifying effective intervention strategies to combat age-related decline in mobility and brain health is a priority. The primary aim of our study was to examine whether 12 months of aerobic training (AT) versus balance and toning (BAT) exercises moderates the relationship between change in mobility and change in basal ganglia volume in older adults. Design Secondary analysis of a randomized controlled trial. Setting Champaign-Urbana, Illinois. Participants Community-dwelling older adults (N = 101; mean age = 66.41 years) Intervention 12-month exercise trial with two groups: AT and BAT. Measurements Mobility was assessed by the Timed Up and Go (TUG) test. Basal ganglia (putamen, caudate nucleus, pallidum) was segmented from T1-weighted MR images using FIRST. Measurements were obtained at baseline and trial completion. Hierarchical multiple regression was conducted to examine whether exercise mode moderates the relationship between change in mobility and change in basal ganglia volume over 12 months. Age, sex, and education were included as covariates. Results Exercise mode significantly moderated the relationship between change in mobility and change in left putamen volume. Specifically, for the AT group, volume of the left putamen did not change, regardless of change in mobility. Similarly, in the BAT group, those who improved their mobility most over 12 months had no change in left putamen volume; however, those who declined in mobility levels significantly decreased in left putamen volume. Conclusion Our primary finding that older adults who engage in 12 months of balance and tone training and improve mobility exhibit maintenance of brain volume in a key region responsible for motor control provides compelling evidence that such exercises can contribute to the promotion of functional independence and healthy aging. PMID:26782858

  18. Analysis of structural dynamic data from Skylab. Volume 2: Skylab analytical and test model data

    NASA Technical Reports Server (NTRS)

    Demchak, L.; Harcrow, H.

    1976-01-01

    The orbital configuration test modal data, analytical test correlation modal data, and analytical flight configuration modal data are presented. Tables showing the generalized mass contributions (GMCs) for each of the thirty tests modes are given along with the two dimensional mode shape plots and tables of GMCs for the test correlated analytical modes. The two dimensional mode shape plots for the analytical modes and uncoupled and coupled modes of the orbital flight configuration at three development phases of the model are included.

  19. A study of application of remote sensing to river forecasting. Volume 1: Executive summary

    NASA Technical Reports Server (NTRS)

    1975-01-01

    A project is described whose goal was to define, implement and evaluate a pilot demonstration test to show the practicability of applying remotely sensed data to operational river forecasting in gaged or previously ungaged watersheds. A secondary objective was to provide NASA with documentation describing the computer programs that comprise the streamflow forecasting simulation model used. A computer-based simulation model was adapted to a streamflow forecasting application and implemented in an IBM System/360 Model 44 computer, operating in a dedicated mode, with operator interactive control through a Model 2250 keyboard/graphic CRT terminal. The test site whose hydrologic behavior was simulated is a small basin (365 square kilometers) designated Town Creek near Geraldine, Alabama.

  20. Multilayered metal-insulator nanocavities: toward tunable multi-resonance nano-devices for integrated optics

    NASA Astrophysics Data System (ADS)

    Song, Junyeob; Zhou, Wei

    2017-02-01

    Plasmonic nanocavities can control light flows and enhance light-mater interactions at subwavelength scale, and thus can potentially be used as nanoscale components in integrated optics systems either for passive optical coupling, or for active optical modulation and emission. In this work, we investigated a new type of multilayered metal-insulator optical nanocavities that can support multiple localized plasmon resonances with ultra-small mode volumes. The total number of resonance peaks and their resonance wavelengths can be freely and accurately controlled by simple geometric design rules. Multi-resonance plasmonic nanocavities can serve as a nanoscale wavelength-multiplexed optical components in integrated optics systems, such as optical couplers, light emitters, nanolasers, optical sensors, and optical modulators.

  1. Using resting-state fMRI to assess the effect of aerobic exercise on functional connectivity of the DLPFC in older overweight adults.

    PubMed

    Prehn, Kristin; Lesemann, Anne; Krey, Georgia; Witte, A Veronica; Köbe, Theresa; Grittner, Ulrike; Flöel, Agnes

    2017-08-23

    Cardiovascular fitness is thought to exert beneficial effects on brain function and might delay the onset of cognitive decline. Empirical evidence of exercise-induced cognitive enhancement, however, has not been conclusive, possibly due to short intervention times in clinical trials. Resting-state functional connectivity (RSFC) has been proposed asan early indicator for intervention-induced changes. Here, we conducted a study in which healthy older overweight subjects took either part in a moderate aerobic exercise program over 6months (AE group; n=11) or control condition of non-aerobic stretching and toning (NAE group; n=18). While cognitive and gray matter volume changes were rather small (i.e., appeared only in certain sub-scores without Bonferroni correction for multiple comparisons or using small volume correction), we found significantly increased RSFC after training between dorsolateral prefrontal cortex and superior parietal gyrus/precuneus in the AE compared to the NAE group. This intervention study demonstrates an exercise-induced modulation of RSFC between key structures of the executive control and default mode networks, which might mediate an interaction between task-positive and task-negative brain activation required for task switching. Results further emphasize the value of RSFC asa sensitive biomarker for detecting early intervention-related cognitive improvements in clinical trials. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. In Vitro and In Vivo Investigation of High-Intensity Focused Ultrasound (HIFU) Hat-Type Ablation Mode

    PubMed Central

    Dai, Hongya; Chen, Fei; Yan, Sijing; Ding, Xiaoya; Ma, Dazhao; Wen, Jing; Xu, Die; Zou, Jianzhong

    2017-01-01

    Background The aim of this study was to investigate the feasibility of the application of high-intensity focused ultrasound (HIFU) hat-type ablation mode in in vitro and in vivo models, and to compare the ablation effects of different parameter combinations. Material/Methods HIFU hat-type ablation was performed in isolated bovine liver tissue and in the liver tissue in living rabbits, and the coagulative necrosis for different parameter combinations (plane angles and irradiation order) was investigated. We also analyzed and compared the ablation effects of traditional ablation and hat-type ablation modes. Coagulative necrosis morphology was detected with TTC staining, and the coagulative necrosis volume and energy efficiency factor (EEF) were calculated and compared. Results Coagulative necrosis was observed in all the ablated groups, and the coagulative necrosis volume was much larger than the irradiation area. The coagulative necrosis induced by the hat-type ablation was more regular and controllable than the traditional ablation. The angles between the ablation planes determined the coagulative necrosis morphology, but did not affect the coagulative necrosis volume. Moreover, the irradiation order significantly influenced the coagulative necrosis. Importantly, under certain conditions, hat-type ablation achieved higher efficiency compared with the traditional ablation mode. Conclusions Compared with the traditional ablation mode, HIFU hat-type ablation effectively shortened the irradiation time, reduced the over-accumulation of energy, and increased the HIFU ablation efficiency. PMID:28699626

  3. In Vitro and In Vivo Investigation of High-Intensity Focused Ultrasound (HIFU) Hat-Type Ablation Mode.

    PubMed

    Dai, Hongya; Chen, Fei; Yan, Sijing; Ding, Xiaoya; Ma, Dazhao; Wen, Jing; Xu, Die; Zou, Jianzhong

    2017-07-12

    BACKGROUND The aim of this study was to investigate the feasibility of the application of high-intensity focused ultrasound (HIFU) hat-type ablation mode in in vitro and in vivo models, and to compare the ablation effects of different parameter combinations. MATERIAL AND METHODS HIFU hat-type ablation was performed in isolated bovine liver tissue and in the liver tissue in living rabbits, and the coagulative necrosis for different parameter combinations (plane angles and irradiation order) was investigated. We also analyzed and compared the ablation effects of traditional ablation and hat-type ablation modes. Coagulative necrosis morphology was detected with TTC staining, and the coagulative necrosis volume and energy efficiency factor (EEF) were calculated and compared. RESULTS Coagulative necrosis was observed in all the ablated groups, and the coagulative necrosis volume was much larger than the irradiation area. The coagulative necrosis induced by the hat-type ablation was more regular and controllable than the traditional ablation. The angles between the ablation planes determined the coagulative necrosis morphology, but did not affect the coagulative necrosis volume. Moreover, the irradiation order significantly influenced the coagulative necrosis. Importantly, under certain conditions, hat-type ablation achieved higher efficiency compared with the traditional ablation mode. CONCLUSIONS Compared with the traditional ablation mode, HIFU hat-type ablation effectively shortened the irradiation time, reduced the over-accumulation of energy, and increased the HIFU ablation efficiency.

  4. Effects of Long- and Intermediate-Wavelength Nonuniformities on Hot-Spot Energetics of Hydrodynamic Equivalent Targets

    NASA Astrophysics Data System (ADS)

    Bose, A.; Betti, R.; Woo, K. M.; Christopherson, A. R.; Shvarts, D.

    2015-11-01

    The impact of intermediate- and low-mode nonuniformities on the performance of inertial confinement fusion (ICF) implosions is investigated by a detailed study of hot-spot energetics. It is found that low- (1 ~ 2) and intermediate-mode (1 >= 10) asymmetries affect the hot-spot hydrodynamics in very different ways. It is observed that for low-mode asymmetries, the fusion yield decreases because of a significant reduction in hot-spot pressure while the neutron-averaged hot-spot volume remains comparable to that of unperturbed (clean) simulations. On the other hand, implosions with moderate-amplitude, intermediate-wavelength modes, which are amplified by the Rayleigh-Taylor instability (RTI), exhibit a fusion-yield degradation primarily caused by a reduction in the burn volume without significant degradation of the pressure. For very large amplitudes, the intermediate modes show a ``secondary piston effect,'' where the converging RTI spikes compress a much smaller volume, allowing for a secondary conversion of the shell's kinetic energy to internal energy at a central region. Understanding the effects of nonuniformities on the hot-spot energetics provides valuable insight in determining the causes of performance degradation in current ICF experiments. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944 and DE-FC02-04ER54789 (Fusion Science Center).

  5. Prediction of Packed Cell Volume after Whole Blood Transfusion in Small Ruminants and South American Camelids: 80 Cases (2006-2016).

    PubMed

    Luethy, D; Stefanovski, D; Salber, R; Sweeney, R W

    2017-11-01

    Calculation of desired whole blood transfusion volume relies on an estimate of an animal's circulating blood volume, generally accepted to be 0.08 L/kg or 8% of the animal's body weight in kilograms. To use packed cell volume before and after whole blood transfusion to evaluate the accuracy of a commonly used equation to predict packed cell volume after transfusion in small ruminants and South American camelids; to determine the nature and frequency of adverse transfusion reactions in small ruminants and camelids after whole blood transfusion. Fifty-eight small ruminants and 22 alpacas that received whole blood transfusions for anemia. Retrospective case series; medical record review for small ruminants and camelids that received whole blood transfusions during hospitalization. Mean volume of distribution of blood as a fraction of body weight in sheep (0.075 L/kg, 7.5% BW) and goats (0.076 L/kg, 7.6% BW) differed significantly (P < 0.01) from alpacas (0.103 L/kg, 10.3% BW). Mild transfusion reactions were noted in 16% of transfusions. The generally accepted value of 8% for circulating blood volume (volume of distribution of blood) is adequate for calculation of transfusion volumes; however, use of the species-specific circulating blood volume can improve calculation of transfusion volume to predict and achieve desired packed cell volume. The incidence of transfusion reactions in small ruminants and camelids is low. Copyright © 2017 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

  6. Characteristics of columnar aerosol optical and microphysical properties retrieved from the sun photometer and its impact on radiative forcing over Skukuza (South Africa) during 1999-2010.

    PubMed

    Adesina, Ayodele Joseph; Piketh, Stuart; Kanike, Raghavendra Kumar; Venkataraman, Sivakumar

    2017-07-01

    The detailed analysis of columnar optical and microphysical properties of aerosols obtained from the AErosol RObotic NETwork (AERONET) Cimel sun photometer operated at Skukuza (24.98° S, 31.60° E, 150 m above sea level), South Africa was carried out using the level 2.0 direct sun and inversion products measured during 1999-2010. The observed aerosol optical depth (AOD) was generally low over the region, with high values noted in late winter (August) and mid-spring (September and October) seasons. The major aerosol types found during the study period were made of 3.74, 69.63, 9.34, 8.83, and 8.41% for polluted dust (PD), polluted continental (PC), non-absorbing (NA), slightly absorbing (SA), and moderately absorbing (MA) aerosols, respectively. Much attention was given to the aerosol fine- and coarse-modes deduced from the particle volume concentration, effective radius, and fine-mode volume fraction. The aerosol volume size distribution pattern was found to be bimodal with the fine-mode showing predominance relative to coarse-mode during the winter and spring seasons, owing to the onset of the biomass burning season. The mean values of total, fine-, and coarse-mode volume particle concentrations were 0.07 ± 0.04, 0.03 ± 0.03, and 0.04 ± 0.02 μm 3  μm -2 , respectively, whereas the mean respective effective radii observed at Skukuza for the abovementioned modes were 0.35 ± 0.17, 0.14 ± 0.02, and 2.08 ± 0.02 μm. The averaged shortwave direct aerosol radiative forcing (ARF) observed within the atmosphere was found to be positive (absorption or heating effect), whereas the negative forcing in the surface and TOA depicted significant cooling effect due to more scattering type particles.

  7. 2D materials in electro-optic modulation: energy efficiency, electrostatics, mode overlap, material transfer and integration

    NASA Astrophysics Data System (ADS)

    Ma, Zhizhen; Hemnani, Rohit; Bartels, Ludwig; Agarwal, Ritesh; Sorger, Volker J.

    2018-02-01

    Here we discuss the physics of electro-optic modulators deploying 2D materials. We include a scaling laws analysis and show how energy-efficiency and speed change for three underlying cavity systems as a function of critical device length scaling. A key result is that the energy-per-bit of the modulator is proportional to the volume of the device, thus making the case for submicron-scale modulators possible deploying a plasmonic optical mode. We then show how Graphene's Pauli-blocking modulation mechanism is sensitive to the device operation temperature, whereby a reduction of the temperature enables a 10× reduction in modulator energy efficiency. Furthermore, we show how the high-index tunability of graphene is able to compensate for the small optical overlap factor of 2D-based material modulators, which is unlike classical silicon-based dispersion devices. Lastly, we demonstrate a novel method towards a 2D material printer suitable for cross-contamination free and on-demand printing. The latter paves the way to integrate 2D materials seamlessly into taped-out photonic chips.

  8. Energy spectrum of tearing mode turbulence in sheared background field

    NASA Astrophysics Data System (ADS)

    Hu, Di; Bhattacharjee, Amitava; Huang, Yi-Min

    2018-06-01

    The energy spectrum of tearing mode turbulence in a sheared background magnetic field is studied in this work. We consider the scenario where the nonlinear interaction of overlapping large-scale modes excites a broad spectrum of small-scale modes, generating tearing mode turbulence. The spectrum of such turbulence is of interest since it is relevant to the small-scale back-reaction on the large-scale field. The turbulence we discuss here differs from traditional MHD turbulence mainly in two aspects. One is the existence of many linearly stable small-scale modes which cause an effective damping during the energy cascade. The other is the scale-independent anisotropy induced by the large-scale modes tilting the sheared background field, as opposed to the scale-dependent anisotropy frequently encountered in traditional critically balanced turbulence theories. Due to these two differences, the energy spectrum deviates from a simple power law and takes the form of a power law multiplied by an exponential falloff. Numerical simulations are carried out using visco-resistive MHD equations to verify our theoretical predictions, and a reasonable agreement is found between the numerical results and our model.

  9. Single Mode Air-Clad Single Crystal Sapphire Optical Fiber

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hill, Cary; Homa, Dan; Yu, Zhihao

    The observation of single mode propagation in an air-clad single crystal sapphire optical fiber at wavelengths at and above 783 nm is presented for the first time. A high-temperature wet acid etching method was used to reduce the diameter of a 10 cm length of commercially-sourced sapphire fiber from 125 micrometers to 6.5 micrometers, and far-field imaging provided modal information at intervals as the fiber diameter decreased. Modal volume was shown to decrease with decreasing diameter, and single mode behavior was observed at the minimum diameter achieved. While weakly-guiding approximations are generally inaccurate for low modal volume optical fiber withmore » high core-cladding refractive index disparity, consistency between these approximations and experimental results was observed when the effective numerical aperture was measured and substituted for the theoretical numerical aperture in weakly-guiding approximation calculations. With the demonstration of very low modal volume in sapphire at fiber diameters much larger than anticipated by legacy calculations, the resolution of sapphire fiber distributed sensors may be increased and other sensing schemes requiring very low modal volume, such as fiber Bragg gratings, may be realized in extreme environment applications.« less

  10. Single Mode Air-Clad Single Crystal Sapphire Optical Fiber

    DOE PAGES

    Hill, Cary; Homa, Dan; Yu, Zhihao; ...

    2017-05-03

    The observation of single mode propagation in an air-clad single crystal sapphire optical fiber at wavelengths at and above 783 nm is presented for the first time. A high-temperature wet acid etching method was used to reduce the diameter of a 10 cm length of commercially-sourced sapphire fiber from 125 micrometers to 6.5 micrometers, and far-field imaging provided modal information at intervals as the fiber diameter decreased. Modal volume was shown to decrease with decreasing diameter, and single mode behavior was observed at the minimum diameter achieved. While weakly-guiding approximations are generally inaccurate for low modal volume optical fiber withmore » high core-cladding refractive index disparity, consistency between these approximations and experimental results was observed when the effective numerical aperture was measured and substituted for the theoretical numerical aperture in weakly-guiding approximation calculations. With the demonstration of very low modal volume in sapphire at fiber diameters much larger than anticipated by legacy calculations, the resolution of sapphire fiber distributed sensors may be increased and other sensing schemes requiring very low modal volume, such as fiber Bragg gratings, may be realized in extreme environment applications.« less

  11. Vibration Method for Tracking the Resonant Mode and Impedance of a Microwave Cavity

    NASA Technical Reports Server (NTRS)

    Barmatz, M.; Iny, O.; Yiin, T.; Khan, I.

    1995-01-01

    A vibration technique his been developed to continuously maintain mode resonance and impedance much between a constant frequency magnetron source and resonant cavity. This method uses a vibrating metal rod to modulate the volume of the cavity in a manner equivalent to modulating an adjustable plunger. A similar vibrating metal rod attached to a stub tuner modulates the waveguide volume between the source and cavity. A phase sensitive detection scheme determines the optimum position of the adjustable plunger and stub turner during processing. The improved power transfer during the heating of a 99.8% pure alumina rod was demonstrated using this new technique. Temperature-time and reflected power-time heating curves are presented for the cases of no tracking, impedance tracker only, mode tracker only and simultaneous impedance and mode tracking. Controlled internal melting of an alumina rod near 2000 C using both tracking units was also demonstrated.

  12. Experimental identification of nonlinear coupling between (intermediate, small)-scale microturbulence and an MHD mode in the core of a superconducting tokamak

    NASA Astrophysics Data System (ADS)

    Sun, P. J.; Li, Y. D.; Ren, Y.; Zhang, X. D.; Wu, G. J.; Xu, L. Q.; Chen, R.; Li, Q.; Zhao, H. L.; Zhang, J. Z.; Shi, T. H.; Wang, Y. M.; Lyu, B.; Hu, L. Q.; Li, J.; The EAST Team

    2018-01-01

    In this paper, we present clear experimental evidence of core region nonlinear coupling between (intermediate, small)-scale microturbulence and an magnetohydrodynamics (MHD) mode during the current ramp-down phase in a set of L-mode plasma discharges in the experimental advanced superconducting tokamak (EAST, Wan et al (2006 Plasma Sci. Technol. 8 253)). Density fluctuations of broadband microturbulence (k\\perpρi˜2{-}5.2 ) and the MHD mode (toroidal mode number m = -1 , poloidal mode number n = 1 ) are measured simultaneously, using a four-channel tangential CO2 laser collective scattering diagnostic in core plasmas. The nonlinear coupling between the broadband microturbulence and the MHD mode is directly demonstrated by showing a statistically significant bicoherence and modulation of turbulent density fluctuation amplitude by the MHD mode.

  13. Generation of Magnetohydrodynamic Waves in Low Solar Atmospheric Flux Tubes by Photospheric Motions

    NASA Astrophysics Data System (ADS)

    Mumford, S. J.; Fedun, V.; Erdélyi, R.

    2015-01-01

    Recent ground- and space-based observations reveal the presence of small-scale motions between convection cells in the solar photosphere. In these regions, small-scale magnetic flux tubes are generated via the interaction of granulation motion and the background magnetic field. This paper studies the effects of these motions on magnetohydrodynamic (MHD) wave excitation from broadband photospheric drivers. Numerical experiments of linear MHD wave propagation in a magnetic flux tube embedded in a realistic gravitationally stratified solar atmosphere between the photosphere and the low choromosphere (above β = 1) are performed. Horizontal and vertical velocity field drivers mimic granular buffeting and solar global oscillations. A uniform torsional driver as well as Archimedean and logarithmic spiral drivers mimic observed torsional motions in the solar photosphere. The results are analyzed using a novel method for extracting the parallel, perpendicular, and azimuthal components of the perturbations, which caters to both the linear and non-linear cases. Employing this method yields the identification of the wave modes excited in the numerical simulations and enables a comparison of excited modes via velocity perturbations and wave energy flux. The wave energy flux distribution is calculated to enable the quantification of the relative strengths of excited modes. The torsional drivers primarily excite Alfvén modes (≈60% of the total flux) with small contributions from the slow kink mode, and, for the logarithmic spiral driver, small amounts of slow sausage mode. The horizontal and vertical drivers primarily excite slow kink or fast sausage modes, respectively, with small variations dependent upon flux surface radius.

  14. An experimental system for the study of active vibration control - Development and modeling

    NASA Astrophysics Data System (ADS)

    Batta, George R.; Chen, Anning

    A modular rotational vibration system designed to facilitate the study of active control of vibrating systems is discussed. The model error associated with four common types of identification problems has been studied. The general multiplicative uncertainty shape for a vibration system is small in low frequencies, large at high frequencies. The frequency-domain error function has sharp peaks near the frequency of each mode. The inability to identify a high-frequency mode causes an increase of uncertainties at all frequencies. Missing a low-frequency mode causes the uncertainties to be much larger at all frequencies than missing a high-frequency mode. Hysteresis causes a small increase of uncertainty at low frequencies, but its overall effect is relatively small.

  15. Improved scatterer property estimates from ultrasound backscatter for small gate lengths using a gate-edge correction factor

    NASA Astrophysics Data System (ADS)

    Oelze, Michael L.; O'Brien, William D.

    2004-11-01

    Backscattered rf signals used to construct conventional ultrasound B-mode images contain frequency-dependent information that can be examined through the backscattered power spectrum. The backscattered power spectrum is found by taking the magnitude squared of the Fourier transform of a gated time segment corresponding to a region in the scattering volume. When a time segment is gated, the edges of the gated regions change the frequency content of the backscattered power spectrum due to truncating of the waveform. Tapered windows, like the Hanning window, and longer gate lengths reduce the relative contribution of the gate-edge effects. A new gate-edge correction factor was developed that partially accounted for the edge effects. The gate-edge correction factor gave more accurate estimates of scatterer properties at small gate lengths compared to conventional windowing functions. The gate-edge correction factor gave estimates of scatterer properties within 5% of actual values at very small gate lengths (less than 5 spatial pulse lengths) in both simulations and from measurements on glass-bead phantoms. While the gate-edge correction factor gave higher accuracy of estimates at smaller gate lengths, the precision of estimates was not improved at small gate lengths over conventional windowing functions. .

  16. Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study.

    PubMed

    Dugernier, Jonathan; Reychler, Gregory; Wittebole, Xavier; Roeseler, Jean; Depoortere, Virginie; Sottiaux, Thierry; Michotte, Jean-Bernard; Vanbever, Rita; Dugernier, Thierry; Goffette, Pierre; Docquier, Marie-Agnes; Raftopoulos, Christian; Hantson, Philippe; Jamar, François; Laterre, Pierre-François

    2016-12-01

    Volume-controlled ventilation has been suggested to optimize lung deposition during nebulization although promoting spontaneous ventilation is targeted to avoid ventilator-induced diaphragmatic dysfunction. Comparing topographic aerosol lung deposition during volume-controlled ventilation and spontaneous ventilation in pressure support has never been performed. The aim of this study was to compare lung deposition of a radiolabeled aerosol generated with a vibrating-mesh nebulizer during invasive mechanical ventilation, with two modes: pressure support ventilation and volume-controlled ventilation. Seventeen postoperative neurosurgery patients without pulmonary disease were randomly ventilated in pressure support or volume-controlled ventilation. Diethylenetriaminepentaacetic acid labeled with technetium-99m (2 mCi/3 mL) was administrated using a vibrating-mesh nebulizer (Aerogen Solo(®), provided by Aerogen Ltd, Galway, Ireland) connected to the endotracheal tube. Pulmonary and extrapulmonary particles deposition was analyzed using planar scintigraphy. Lung deposition was 10.5 ± 3.0 and 15.1 ± 5.0 % of the nominal dose during pressure support and volume-controlled ventilation, respectively (p < 0.05). Higher endotracheal tube and tracheal deposition was observed during pressure support ventilation (27.4 ± 6.6 vs. 20.7 ± 6.0 %, p < 0.05). A similar penetration index was observed for the right (p = 0.210) and the left lung (p = 0.211) with both ventilation modes. A high intersubject variability of lung deposition was observed with both modes regarding lung doses, aerosol penetration and distribution between the right and the left lung. In the specific conditions of the study, volume-controlled ventilation was associated with higher lung deposition of nebulized particles as compared to pressure support ventilation. The clinical benefit of this effect warrants further studies. Clinical trial registration NCT01879488.

  17. Stability of metal-rich very massive stars

    NASA Astrophysics Data System (ADS)

    Goodman, J.; White, Christopher J.

    2016-02-01

    We revisit the stability of very massive non-rotating main-sequence stars at solar metallicity, with the goal of understanding whether radial pulsations set a physical upper limit to stellar mass. Models of up to 938 solar masses are constructed with the MESA code, and their linear stability in the fundamental mode, assumed to be the most dangerous, is analysed with a fully non-adiabatic method. Models above 100 M⊙ have extended tenuous atmospheres (`shelves') that affect the stability of the fundamental. Even when positive, this growth rate is small, in agreement with previous results. We argue that small growth rates lead to saturation at small amplitudes that are not dangerous to the star. A mechanism for saturation is demonstrated involving non-linear parametric coupling to short-wavelength g-modes and the damping of the latter by radiative diffusion. The shelves are subject to much more rapidly growing strange modes. This also agrees with previous results but is extended here to higher masses. The strange modes probably saturate via shocks rather than mode coupling but have very small amplitudes in the core, where almost all of the stellar mass resides. Although our stellar models are hydrostatic, the structure of their outer parts suggests that optically thick winds, driven by some combination of radiation pressure, transonic convection, and strange modes, are more likely than pulsation in the fundamental mode to limit the main-sequence lifetime.

  18. Propulsion and airframe aerodynamic interactions of supersonic V/STOL configurations. Volume 4: Summary

    NASA Technical Reports Server (NTRS)

    Zilz, D. E.; Wallace, H. W.; Hiley, P. E.

    1985-01-01

    A wind tunnel model of a supersonic V/STOL fighter configuration has been tested to measure the aerodynamic interaction effects which can result from geometrically close-coupled propulsion system/airframe components. The approach was to configure the model to represent two different test techniques. One was a conventional test technique composed of two test modes. In the Flow-Through mode, absolute configuration aerodynamics are measured, including inlet/airframe interactions. In the Jet-Effects mode, incremental nozzle/airframe interactions are measured. The other test technique is a propulsion simulator approach, where a sub-scale, externally powered engine is mounted in the model. This allows proper measurement of inlet/airframe and nozzle/airframe interactions simultaneously. This is Volume 4 of 4: Final Report- Summary.

  19. Research on Evaluation of resource allocation efficiency of transportation system based on DEA

    NASA Astrophysics Data System (ADS)

    Zhang, Zhehui; Du, Linan

    2017-06-01

    In this paper, we select the time series data onto 1985-2015 years, construct the land (shoreline) resources, capital and labor as inputs. The index system of the output is freight volume and passenger volume, we use Quantitative analysis based on DEA method evaluated the resource allocation efficiency of railway, highway, water transport and civil aviation in China. Research shows that the resource allocation efficiency of various modes of transport has obvious difference, and the impact on scale efficiency is more significant. The most important two ways to optimize the allocation of resources to improve the efficiency of the combination of various modes of transport is promoting the co-ordination of various modes of transport and constructing integrated transportation system.

  20. Raman tensor elements for tetragonal BaTiO3 and their use for in-plane domain texture assessments

    NASA Astrophysics Data System (ADS)

    Deluca, Marco; Higashino, Masayuki; Pezzotti, Giuseppe

    2007-08-01

    A quantitative assessment of c-axis oriented domains in a textured BaTiO3 (BT) single crystal has been carried out by polarized Raman microprobe spectroscopy. The relative intensity modulation of the Raman phonon modes has been theoretically modeled as a function of crystal rotation and linked to the volume fraction of c-axis oriented domains. Raman tensor elements have also been experimentally determined for the Ag and B1 vibrational modes. As an application, the internal in-plane texture and the volume fraction of c-oriented domains in the BT single crystal have been nondestructively visualized by monitoring the relative intensity of Ag and B1 Raman modes.

  1. On demand manufacturing of patient-specific liquid capsules via co-ordinated 3D printing and liquid dispensing.

    PubMed

    Okwuosa, Tochukwu C; Soares, Cindy; Gollwitzer, Verena; Habashy, Rober; Timmins, Peter; Alhnan, Mohamed A

    2018-06-15

    A method for the production of liquid capsules with the potential of modifying drug dose and release is presented. For the first time, the co-ordinated use of fused deposition modelling (FDM), 3D printing and liquid dispensing to fabricate individualised dosage form on demand in a fully automated fashion has been demonstrated. Polymethacrylate shells (Eudragit EPO and RL) for immediate and extended release were fabricated using FDM 3D printing and simultaneously filled using a computer-controlled liquid dispenser loaded with model drug solution (theophylline) or suspension (dipyridamole). The impact of printing modes: simultaneous shell printing and filling (single-phase) or sequential 3D printing of shell bottom, filling and shell cap (multi-phase), nozzle size, syringe volume, and shell structure has been reported. The use of shell thickness of 1.6 mm, and concentric architecture allowed successful containment of liquid core whilst maintaining the release properties of the 3D printed liquid capsule. The linear relationship between the theoretical and the actual volumes from the dispenser reflected its potential for accurate dosing (R 2  = 0.9985). Modifying the shell thickness of Eudragit RL capsule allowed a controlled extended drug release without the need for formulation change. Owing to its low cost and versatility, this approach can be adapted to wide spectrum of liquid formulations such as small and large molecule solutions and obviate the need for compatibility with the high temperature of FDM 3D printing process. In a clinical setting, health care staff will be able to instantly manufacture in small volumes liquid capsules with individualised dose contents and release pattern in response to specific patient's needs. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. No-Touch Radiofrequency Ablation: A Comparison of Switching Bipolar and Switching Monopolar Ablation in Ex Vivo Bovine Liver

    PubMed Central

    Chang, Won; Lee, Sang Min; Han, Joon Koo

    2017-01-01

    Objective To evaluate the feasibility, efficiency, and safety of no-touch switching bipolar (SB) and switching monopolar (SM) radiofrequency ablation (RFA) using ex vivo bovine livers. Materials and Methods A pork loin cube was inserted as a tumor mimicker in the bovine liver block; RFA was performed using the no-touch technique in the SM (group A1; 10 minutes, n = 10, group A2; 15 minutes, n = 10) and SB (group B; 10 minutes, n = 10) modes. The groups were compared based on the creation of confluent necrosis with sufficient safety margins, the dimensions, and distance between the electrode and ablation zone margin (DEM). To evaluate safety, small bowel loops were placed above the liver surface and 30 additional ablations were performed in the same groups. Results Confluent necroses with sufficient safety margins were created in all specimens. SM RFA created significantly larger volumes of ablation compared to SB RFA (all p < 0.001). The DEM of group B was significantly lower than those of groups A1 and A2 (all p < 0.001). Although thermal injury to the small bowel was noted in 90%, 100%, and 30% of the cases in groups A1, A2, and B, respectively, full depth injury was noted only in 60% of group A2 cases. Conclusion The no-touch RFA technique is feasible in both the SB and SM modes; however, SB RFA appears to be more advantageous compared to SM RFA in the creation of an ablation zone while avoiding the unnecessary creation of an adjacent parenchymal ablation zone or adjacent small bowel injuries. PMID:28246508

  3. Seismic modeling of multidimensional heterogeneity scales of Mallik gas hydrate reservoirs, Northwest Territories of Canada

    NASA Astrophysics Data System (ADS)

    Huang, Jun-Wei; Bellefleur, Gilles; Milkereit, Bernd

    2009-07-01

    In hydrate-bearing sediments, the velocity and attenuation of compressional and shear waves depend primarily on the spatial distribution of hydrates in the pore space of the subsurface lithologies. Recent characterizations of gas hydrate accumulations based on seismic velocity and attenuation generally assume homogeneous sedimentary layers and neglect effects from large- and small-scale heterogeneities of hydrate-bearing sediments. We present an algorithm, based on stochastic medium theory, to construct heterogeneous multivariable models that mimic heterogeneities of hydrate-bearing sediments at the level of detail provided by borehole logging data. Using this algorithm, we model some key petrophysical properties of gas hydrates within heterogeneous sediments near the Mallik well site, Northwest Territories, Canada. The modeled density, and P and S wave velocities used in combination with a modified Biot-Gassmann theory provide a first-order estimate of the in situ volume of gas hydrate near the Mallik 5L-38 borehole. Our results suggest a range of 528 to 768 × 106 m3/km2 of natural gas trapped within hydrates, nearly an order of magnitude lower than earlier estimates which did not include effects of small-scale heterogeneities. Further, the petrophysical models are combined with a 3-D finite difference modeling algorithm to study seismic attenuation due to scattering and leaky mode propagation. Simulations of a near-offset vertical seismic profile and cross-borehole numerical surveys demonstrate that attenuation of seismic energy may not be directly related to the intrinsic attenuation of hydrate-bearing sediments but, instead, may be largely attributed to scattering from small-scale heterogeneities and highly attenuate leaky mode propagation of seismic waves through larger-scale heterogeneities in sediments.

  4. 40 CFR 1054.635 - What special provisions apply for small-volume engine and equipment manufacturers?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... special provisions in this part for small-volume engine and equipment manufacturers. (a) If you qualify... qualify under paragraph (1) or (2) of the definition of small-volume engine manufacturer or under...) Additional lead time and other provisions related to the transition to new emission standards. See § 1054.145...

  5. Speed-volume relationship and headway distribution analysis of motorcycle (case study: Teuku Nyak Arief Road)

    NASA Astrophysics Data System (ADS)

    Prahara, E.; Prasetya, R. A.

    2018-01-01

    In many developing countries, transportation modes are more varied than the other country. For example, in Jakarta, Indonesia, in some roadway, motorcycle is the most dominant vehicle, with total volume is four times higher than a passenger car. Thus, the traffic characteristic in motorcycle-dominated traffic differs from a common traffic situation. The purpose of this study is to apply the concept and theory developed to analyze motorcycle behaviour under motorcycle-dominated traffic condition. The survey is applied by recording the traffic flow movement of research location at specified time period. The macroscopic characteristic analyzed in this research is a speed-flow relationship based on motorcycle equivalent unit (MCU). Furthermore, a detail microscopic characteristic analyzed that is motorcycle time headway regarding traffic flow. MCU values computed were consists of motorcycle (MC), light vehicle (LV) and heavy vehicle (HV). Those values were calculated 1.00, 6.13 and 10.71 respectively. The speed and volume relationship result is showing a linear regression model with R2 value is 0.58, it can be explained that the correlation between two variables is intermediate. The headway distribution of motorcycle is compatible with the negative exponential distribution which fitted with the proposed theory for a small vehicle such as a motorcycle.

  6. Molecular Volumes and the Stokes-Einstein Equation

    ERIC Educational Resources Information Center

    Edward, John T.

    1970-01-01

    Examines the limitations of the Stokes-Einstein equation as it applies to small solute molecules. Discusses molecular volume determinations by atomic increments, molecular models, molar volumes of solids and liquids, and molal volumes. Presents an empirical correction factor for the equation which applies to molecular radii as small as 2 angstrom…

  7. Deformation mode and strain path dependence of martensite phase transformation in a medium manganese TRIP steel

    DOE PAGES

    Wu, Wei; Wang, Yu-wei; Makrygiannis, Panagiotis; ...

    2017-11-06

    The martensite phase transformation dependence upon deformation modes and strain paths in a medium manganese (10 wt%) TRIP steel stamped into a T-shape panel was quantified through combination of 3D digital image correlation and synchrotron X-ray diffraction. The T-shape emulates a portion of a common anti-intrusion component. The stamping speed was kept intentionally slow (1 mm/s) so as to avoid excessive heat generation. The steel, which belongs to the third generation advanced high strength steel (3GAHSS) family, was chosen for two reasons: (1) it is two-phase, i.e. austenite and ferrite, with martensite resulting from deformation-induced phase transformation; (2) the 66more » vol.% initial retained austenite volume fraction (RAVF) enabled a thorough examination of the martensite phase transformation at large deformation levels without exhaustion. Strain fields were coupled with measured RAVF values of small specimens extracted from specific locations on a formed T-shape panel. This enabled an exploration of the effects of linear, bilinear, and non-linear strain paths as well as deformation modes such as tension, plane strain, biaxial tension, and equibiaxial tension. Results suggest a significant martensite phase transformation dependence on deformation mode and strain path in the absence of fracture and when martensite phase transformation is unaffected by heat generated during forming. In general, the uniaxial and biaxial tension deformation modes facilitate the martensite phase transformation, while the smallest amount of martensite phase transformation occurs under plane strain. Some discussion as to further application of the experimental methods detailed in this study to other 3GAHSS and the effects of fracture on martensite phase transformation is provided.« less

  8. Deformation mode and strain path dependence of martensite phase transformation in a medium manganese TRIP steel

    DOE PAGES

    Wu, Wei; Wang, Yu -Wei; Makrygiannis, Panagiotis; ...

    2017-11-06

    The martensite phase transformation dependence upon deformation modes and strain paths in a medium manganese (10 wt%) TRIP steel stamped into a T-shape panel was quantified through combination of 3D digital image correlation and synchrotron X-ray diffraction. The T-shape emulates a portion of a common anti-intrusion component. The stamping speed was kept intentionally slow (1 mm/s) so as to avoid excessive heat generation. The steel, which belongs to the third generation advanced high strength steel (3GAHSS) family, was chosen for two reasons: (1) it is two-phase, i.e. austenite and ferrite, with martensite resulting from deformation-induced phase transformation; (2) the 66more » vol.% initial retained austenite volume fraction (RAVF) enabled a thorough examination of the martensite phase transformation at large deformation levels without exhaustion. Strain fields were coupled with measured RAVF values of small specimens extracted from specific locations on a formed T-shape panel. This enabled an exploration of the effects of linear, bilinear, and non-linear strain paths as well as deformation modes such as tension, plane strain, biaxial tension, and equibiaxial tension. Results suggest a significant martensite phase transformation dependence on deformation mode and strain path in the absence of fracture and when martensite phase transformation is unaffected by heat generated during forming. In general, the uniaxial and biaxial tension deformation modes facilitate the martensite phase transformation, while the smallest amount of martensite phase transformation occurs under plane strain. In conclusion, some discussion as to further application of the experimental methods detailed in this study to other 3GAHSS and the effects of fracture on martensite phase transformation is provided.« less

  9. Algal Foams Applied in Fixed-Bed Process for Lead(II) Removal Using Recirculation or One-Pass Modes

    PubMed Central

    Wang, Shengye; Vincent, Thierry; Faur, Catherine; Guibal, Eric

    2017-01-01

    The incorporation of brown algae into biopolymer beads or foams for metal sorption has been previously reported. However, the direct use of these biomasses for preparing foams is a new approach. In this study, two kinds of porous foams were prepared by ionotropic gelation using algal biomass (AB, Laminaria digitata) or alginate (as the reference) and applied for Pb(II) sorption. These foams (manufactured as macroporous discs) were packed in filtration holders (simulating fixed-bed column) and the system was operated in either a recirculation or a one-pass mode. Sorption isotherms, uptake kinetics and sorbent reuse were studied in the recirculation mode (analogous to batch system). In the one-pass mode (continuous fixed-bed system), the influence of parameters such as flow rate, feed metal concentration and bed height were investigated on both sorption and desorption. In addition, the effect of Cu(II) on Pb(II) recovery from binary solutions was also studied in terms of both sorption and desorption. Sorption isotherms are well fitted by the Langmuir equation while the pseudo-second order rate equation described well both sorption and desorption kinetic profiles. The study of material regeneration confirms that the reuse of the foams was feasible with a small mass loss, even after 9 cycles. In the one-pass mode, for alginate foams, a slower flow rate led to a smaller saturation volume, while the effect of flow rate was less marked for AB foams. Competitive study suggests that the foams have a preference for Pb(II) over Cu(II) but cannot selectively remove Pb(II) from the binary solution. PMID:29039806

  10. Deformation mode and strain path dependence of martensite phase transformation in a medium manganese TRIP steel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Wei; Wang, Yu -Wei; Makrygiannis, Panagiotis

    The martensite phase transformation dependence upon deformation modes and strain paths in a medium manganese (10 wt%) TRIP steel stamped into a T-shape panel was quantified through combination of 3D digital image correlation and synchrotron X-ray diffraction. The T-shape emulates a portion of a common anti-intrusion component. The stamping speed was kept intentionally slow (1 mm/s) so as to avoid excessive heat generation. The steel, which belongs to the third generation advanced high strength steel (3GAHSS) family, was chosen for two reasons: (1) it is two-phase, i.e. austenite and ferrite, with martensite resulting from deformation-induced phase transformation; (2) the 66more » vol.% initial retained austenite volume fraction (RAVF) enabled a thorough examination of the martensite phase transformation at large deformation levels without exhaustion. Strain fields were coupled with measured RAVF values of small specimens extracted from specific locations on a formed T-shape panel. This enabled an exploration of the effects of linear, bilinear, and non-linear strain paths as well as deformation modes such as tension, plane strain, biaxial tension, and equibiaxial tension. Results suggest a significant martensite phase transformation dependence on deformation mode and strain path in the absence of fracture and when martensite phase transformation is unaffected by heat generated during forming. In general, the uniaxial and biaxial tension deformation modes facilitate the martensite phase transformation, while the smallest amount of martensite phase transformation occurs under plane strain. In conclusion, some discussion as to further application of the experimental methods detailed in this study to other 3GAHSS and the effects of fracture on martensite phase transformation is provided.« less

  11. Deformation mode and strain path dependence of martensite phase transformation in a medium manganese TRIP steel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Wei; Wang, Yu-wei; Makrygiannis, Panagiotis

    The martensite phase transformation dependence upon deformation modes and strain paths in a medium manganese (10 wt%) TRIP steel stamped into a T-shape panel was quantified through combination of 3D digital image correlation and synchrotron X-ray diffraction. The T-shape emulates a portion of a common anti-intrusion component. The stamping speed was kept intentionally slow (1 mm/s) so as to avoid excessive heat generation. The steel, which belongs to the third generation advanced high strength steel (3GAHSS) family, was chosen for two reasons: (1) it is two-phase, i.e. austenite and ferrite, with martensite resulting from deformation-induced phase transformation; (2) the 66more » vol.% initial retained austenite volume fraction (RAVF) enabled a thorough examination of the martensite phase transformation at large deformation levels without exhaustion. Strain fields were coupled with measured RAVF values of small specimens extracted from specific locations on a formed T-shape panel. This enabled an exploration of the effects of linear, bilinear, and non-linear strain paths as well as deformation modes such as tension, plane strain, biaxial tension, and equibiaxial tension. Results suggest a significant martensite phase transformation dependence on deformation mode and strain path in the absence of fracture and when martensite phase transformation is unaffected by heat generated during forming. In general, the uniaxial and biaxial tension deformation modes facilitate the martensite phase transformation, while the smallest amount of martensite phase transformation occurs under plane strain. Some discussion as to further application of the experimental methods detailed in this study to other 3GAHSS and the effects of fracture on martensite phase transformation is provided.« less

  12. Potential seal bypass and caprock storage produced by deformation-band-to-opening-mode-fracture transition at the reservoir/caprock interface

    DOE PAGES

    Raduha, S.; Butler, D.; Mozley, P. S.; ...

    2016-06-18

    Here, we examined the potential impact on CO 2 transport of zones of deformation bands in reservoir rock that transition to opening-mode fractures within overlying caprock. Sedimentological and petrophysical measurements were collected along an approximately 5 m × 5 m outcrop of the Slick Rock and Earthy Members of the Entrada Sandstone on the eastern flank of the San Rafael Swell, Utah, USA. Measured deformation band permeability (2 mD) within the reservoir facies is about three orders of magnitude lower than the host sandstone. Average permeability of the caprock facies (0.0005 mD) is about seven orders of magnitude lower thanmore » the host sandstone. Aperture-based permeability estimates of the opening-mode caprock fractures are high (3.3 × 10 7 mD). High-resolution CO 2–H 2O transport models incorporate these permeability data at the millimeter scale. We then varied fault properties at the reservoir/caprock interface between open fractures and deformation bands as part of a sensitivity study. Numerical modeling results suggest that zones of deformation bands within the reservoir strongly compartmentalize reservoir pressures largely blocking lateral, cross-fault flow of supercritical CO 2. Significant vertical CO 2 transport into the caprock occurred in some scenarios along opening-mode fractures. The magnitude of this vertical CO 2 transport depends on the small-scale geometry of the contact between the opening-mode fracture and the zone of deformation bands, as well as the degree to which fractures penetrate caprock. Finally, the presence of relatively permeable units within the caprock allows storage of significant volumes of CO 2, particularly when the fracture network does not extend all the way through the caprock.« less

  13. The retrospective binning method improves the consistency of phase binning in respiratory-gated PET/CT

    NASA Astrophysics Data System (ADS)

    Didierlaurent, D.; Ribes, S.; Batatia, H.; Jaudet, C.; Dierickx, L. O.; Zerdoud, S.; Brillouet, S.; Caselles, O.; Courbon, F.

    2012-12-01

    This study assesses the accuracy of prospective phase-gated PET/CT data binning and presents a retrospective data binning method that improves image quality and consistency. Respiratory signals from 17 patients who underwent 4D PET/CT were analysed to evaluate the reproducibility of temporal triggers used for the standard phase-based gating method. Breathing signals were reprocessed to implement retrospective PET data binning. The mean and standard deviation of time lags between automatic triggers provided by the Real-time Position Management (RPM, Varian) gating device and inhalation peaks derived from respiratory curves were computed for each patient. The total number of respiratory cycles available for 4D PET/CT according to the binning mode (prospective versus retrospective) was compared. The maximum standardized uptake value (SUVmax), biological tumour volume (BTV) and tumour trajectory measures were determined from the PET/CT images of five patients. Compared to retrospective binning (RB), prospective gating approach led to (i) a significant loss in breathing cycles (15%) and (ii) the inconsistency of data binning due to temporal dispersion of triggers (average 396 ms). Consequently, tumour characterization could be impacted. In retrospective mode, SUVmax was up to 27% higher, where no significant difference appeared in BTV. In addition, prospective mode gave an inconsistent spatial location of the tumour throughout the bins. Improved consistency with breathing patterns and greater motion amplitude of the tumour centroid were observed with retrospective mode. The detection of the tumour motion and trajectory was improved also for small temporal dispersion of triggers. This study shows that the binning mode could have a significant impact on 4D PET images. The consistency of triggers with breathing signals should be checked before clinical use of gated PET/CT images, and our RB method improves 4D PET/CT image quantification.

  14. Electrostatic lower hybrid waves excited by electromagnetic whistler mode waves scattering from planar magnetic-field-aligned plasma density irregularities

    NASA Technical Reports Server (NTRS)

    Bell, T. F.; Ngo, H. D.

    1990-01-01

    This paper presents a theoretical model for electrostatic lower hybrid waves excited by electromagnetic whistler mode waves propagating in regions of the magnetosphere and the topside ionosphere, where small-scale magnetic-field-aligned plasma density irregularities are thought to exist. In this model, the electrostatic waves are excited by linear mode coupling as the incident electromagnetic whistler mode waves scatter from the magnetic-field-aligned plasma density irregularities. Results indicate that high-amplitude short-wavelength (5 to 100 m) quasi-electrostatic whistler mode waves can be excited when electromagnetic whistler mode waves scatter from small-scale planar magnetic-field-aligned plasma density irregularities in the topside ionosphere and magnetosphere.

  15. Ice Ih anomalies: Thermal contraction, anomalous volume isotope effect, and pressure-induced amorphization.

    PubMed

    Salim, Michael A; Willow, Soohaeng Yoo; Hirata, So

    2016-05-28

    Ice Ih displays several anomalous thermodynamic properties such as thermal contraction at low temperatures, an anomalous volume isotope effect (VIE) rendering the volume of D2O ice greater than that of H2O ice, and a pressure-induced transition to the high-density amorphous (HDA) phase. Furthermore, the anomalous VIE increases with temperature, despite its quantum-mechanical origin. Here, embedded-fragment ab initio second-order many-body perturbation (MP2) theory in the quasiharmonic approximation (QHA) is applied to the Gibbs energy of an infinite, proton-disordered crystal of ice Ih at wide ranges of temperatures and pressures. The quantum effect of nuclei moving in anharmonic potentials is taken into account from first principles without any empirical or nonsystematic approximation to either the electronic or vibrational Hamiltonian. MP2 predicts quantitatively correctly the thermal contraction at low temperatures, which is confirmed to originate from the volume-contracting hydrogen-bond bending modes (acoustic phonons). It qualitatively reproduces (but underestimates) the thermal expansion at higher temperatures, caused by the volume-expanding hydrogen-bond stretching (and to a lesser extent librational) modes. The anomalous VIE is found to be the result of subtle cancellations among closely competing isotope effects on volume from all modes. Consequently, even ab initio MP2 with the aug-cc-pVDZ and aug-cc-pVTZ basis sets has difficulty reproducing this anomaly, yielding qualitatively varied predictions of the sign of the VIE depending on such computational details as the choice of the embedding field. However, the temperature growth of the anomalous VIE is reproduced robustly and is ascribed to the librational modes. These solid-state MP2 calculations, as well as MP2 Born-Oppenheimer molecular dynamics, find a volume collapse and a loss of symmetry and long-range order in ice Ih upon pressure loading of 2.35 GPa or higher. Concomitantly, rapid softening of acoustic phonons is observed starting around 2 GPa. They constitute a computational detection of a mechanical instability in ice Ih and the resulting pressure-induced amorphization to HDA.

  16. Ice Ih anomalies: Thermal contraction, anomalous volume isotope effect, and pressure-induced amorphization

    NASA Astrophysics Data System (ADS)

    Salim, Michael A.; Willow, Soohaeng Yoo; Hirata, So

    2016-05-01

    Ice Ih displays several anomalous thermodynamic properties such as thermal contraction at low temperatures, an anomalous volume isotope effect (VIE) rendering the volume of D2O ice greater than that of H2O ice, and a pressure-induced transition to the high-density amorphous (HDA) phase. Furthermore, the anomalous VIE increases with temperature, despite its quantum-mechanical origin. Here, embedded-fragment ab initio second-order many-body perturbation (MP2) theory in the quasiharmonic approximation (QHA) is applied to the Gibbs energy of an infinite, proton-disordered crystal of ice Ih at wide ranges of temperatures and pressures. The quantum effect of nuclei moving in anharmonic potentials is taken into account from first principles without any empirical or nonsystematic approximation to either the electronic or vibrational Hamiltonian. MP2 predicts quantitatively correctly the thermal contraction at low temperatures, which is confirmed to originate from the volume-contracting hydrogen-bond bending modes (acoustic phonons). It qualitatively reproduces (but underestimates) the thermal expansion at higher temperatures, caused by the volume-expanding hydrogen-bond stretching (and to a lesser extent librational) modes. The anomalous VIE is found to be the result of subtle cancellations among closely competing isotope effects on volume from all modes. Consequently, even ab initio MP2 with the aug-cc-pVDZ and aug-cc-pVTZ basis sets has difficulty reproducing this anomaly, yielding qualitatively varied predictions of the sign of the VIE depending on such computational details as the choice of the embedding field. However, the temperature growth of the anomalous VIE is reproduced robustly and is ascribed to the librational modes. These solid-state MP2 calculations, as well as MP2 Born-Oppenheimer molecular dynamics, find a volume collapse and a loss of symmetry and long-range order in ice Ih upon pressure loading of 2.35 GPa or higher. Concomitantly, rapid softening of acoustic phonons is observed starting around 2 GPa. They constitute a computational detection of a mechanical instability in ice Ih and the resulting pressure-induced amorphization to HDA.

  17. Ice Ih anomalies: Thermal contraction, anomalous volume isotope effect, and pressure-induced amorphization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Salim, Michael A.; Willow, Soohaeng Yoo; Hirata, So, E-mail: sohirata@illinois.edu

    Ice Ih displays several anomalous thermodynamic properties such as thermal contraction at low temperatures, an anomalous volume isotope effect (VIE) rendering the volume of D{sub 2}O ice greater than that of H{sub 2}O ice, and a pressure-induced transition to the high-density amorphous (HDA) phase. Furthermore, the anomalous VIE increases with temperature, despite its quantum-mechanical origin. Here, embedded-fragment ab initio second-order many-body perturbation (MP2) theory in the quasiharmonic approximation (QHA) is applied to the Gibbs energy of an infinite, proton-disordered crystal of ice Ih at wide ranges of temperatures and pressures. The quantum effect of nuclei moving in anharmonic potentials ismore » taken into account from first principles without any empirical or nonsystematic approximation to either the electronic or vibrational Hamiltonian. MP2 predicts quantitatively correctly the thermal contraction at low temperatures, which is confirmed to originate from the volume-contracting hydrogen-bond bending modes (acoustic phonons). It qualitatively reproduces (but underestimates) the thermal expansion at higher temperatures, caused by the volume-expanding hydrogen-bond stretching (and to a lesser extent librational) modes. The anomalous VIE is found to be the result of subtle cancellations among closely competing isotope effects on volume from all modes. Consequently, even ab initio MP2 with the aug-cc-pVDZ and aug-cc-pVTZ basis sets has difficulty reproducing this anomaly, yielding qualitatively varied predictions of the sign of the VIE depending on such computational details as the choice of the embedding field. However, the temperature growth of the anomalous VIE is reproduced robustly and is ascribed to the librational modes. These solid-state MP2 calculations, as well as MP2 Born–Oppenheimer molecular dynamics, find a volume collapse and a loss of symmetry and long-range order in ice Ih upon pressure loading of 2.35 GPa or higher. Concomitantly, rapid softening of acoustic phonons is observed starting around 2 GPa. They constitute a computational detection of a mechanical instability in ice Ih and the resulting pressure-induced amorphization to HDA.« less

  18. Comment on 'volume of magma accumulation or withdrawal estimated from surface uplift or subsidence, with application to the 1960 collapse of Kilauea volcano' by P.T. Delaney and D.F. McTigue

    USGS Publications Warehouse

    Johnson, Daniel J.; Sigmundsson, F.; Delaney, P.T.

    2000-01-01

    In volcanoes that store a significant quantity of magma within a subsurface summit reservoir, such as Kilauea, bulk compression of stored magma is an important mode of deformation. Accumulation of magma is also accompanied by crustal deformation, usually manifested at the surface as uplift. These two modes of deformation - bulk compression of resident magma and deformation of the volcanic edifice - act in concert to accommodate the volume of newly added magma. During deflation, the processes reverse and reservoir magma undergoes bulk decompression, the chamber contracts, and the ground surface subsides. Because magma compression plays a role in creating subsurface volume of accommodate magma, magma budget estimates that are derived from surface uplift observations without consideration of magma compression will underestimate actual magma volume changes.

  19. LP01 to LP11 mode convertor based on side-polished small-core single-mode fiber

    NASA Astrophysics Data System (ADS)

    Liu, Yan; Li, Yang; Li, Wei-dong

    2018-03-01

    An all-fiber LP01-LP11 mode convertor based on side-polished small-core single-mode fibers (SMFs) is numerically demonstrated. The linearly polarized incident beam in one arm experiences π shift through a fiber half waveplate, and the side-polished parts merge into an equivalent twin-core fiber (TCF) which spatially shapes the incident LP01 modes to the LP11 mode supported by the step-index few-mode fiber (FMF). Optimum conditions for the highest conversion efficiency are investigated using the beam propagation method (BPM) with an approximate efficiency as high as 96.7%. The proposed scheme can operate within a wide wavelength range from 1.3 μm to1.7 μm with overall conversion efficiency greater than 95%. The effective mode area and coupling loss are also characterized in detail by finite element method (FEM).

  20. The Impact of Surgeon Volume on Perioperative Outcomes in Hysterectomy

    PubMed Central

    Vree, Florentien E. M.; Cohen, Sarah L.; Chavan, Niraj

    2014-01-01

    Background and Objectives: To estimate the effect of surgeon volume on key perioperative outcomes after all modes of hysterectomy. Methods: We performed a review of 1914 hysterectomies performed at a large, academic tertiary-care hospital. Women who underwent abdominal, laparoscopic, vaginal, or robotic hysterectomy for benign non-obstetric indications in 2006, 2009, and 2010 were included. Results: Gynecologic surgeons were categorized according their average annual hysterectomy case volume: low volume (<11 cases per year), intermediate volume (11–50 cases per year), and high-volume (>51 cases per year). Taking all modes of hysterectomy together, surgeries performed by high-volume surgeons required a shorter operative time (155.11 minutes vs 199.19–203.35 minutes, P < .001) and resulted in less estimated blood loss compared with low- and intermediate-volume surgeons (161.09 mL vs 205.58–237.96 mL, P < .001). The 3 surgical volume groups did not differ from each other significantly in the conversion to laparotomy, readmission rate, or incidence of intraoperative or postoperative complications. These findings were maintained when subgroup analyses were performed by type of hysterectomy, with few exceptions. In the subgroup of vaginal hysterectomies by intermediate-volume surgeons, there were slightly more postoperative complications. There were fewer intraoperative complications in laparoscopic/robotic hysterectomies performed by high-volume surgeons, though not statistically significant. Conclusions: Hysterectomies performed by high-volume surgeons at our institution during the 3-year study period were associated with shorter operative times and less estimated blood loss. PMID:24960479

  1. Bragg superlattice for obtaining individual photoluminescence of diamond color centers in dense 3D ensembles

    NASA Astrophysics Data System (ADS)

    Kukushkin, V. A.

    2017-10-01

    A way to significantly increase the spatial resolution of the color center photoluminescence collection in chemically vapor-deposited (CVD) diamond at a fixed exciting beam focal volume is suggested. It is based on the creation of a narrow waveguide for the color center photoluminescence with a small number of allowed vertical indices of guided modes. The waveguide is formed between the top surface of a CVD diamond film and an underlaid mirror—a Bragg superlattice made of interchanging high- and low boron-doped layers of CVD diamond. The guided color center photoluminescence is extracted through the top surface of a CVD diamond film with the frustrated total internal reflection method. According to the results of simulation made for a case when color centers are nitrogen-vacancy (NV) centers, the suggested way allows to increase the maximal value of the NV center concentration still compatible with selective collection of their photoluminescence by several times at a fixed exciting beam focal volume. This increase is provided without the deterioration of the NV center photoluminescence collection efficiency.

  2. Micro-machined resonator oscillator

    DOEpatents

    Koehler, D.R.; Sniegowski, J.J.; Bivens, H.M.; Wessendorf, K.O.

    1994-08-16

    A micro-miniature resonator-oscillator is disclosed. Due to the miniaturization of the resonator-oscillator, oscillation frequencies of one MHz and higher are utilized. A thickness-mode quartz resonator housed in a micro-machined silicon package and operated as a telemetered sensor beacon'' that is, a digital, self-powered, remote, parameter measuring-transmitter in the FM-band. The resonator design uses trapped energy principles and temperature dependence methodology through crystal orientation control, with operation in the 20--100 MHz range. High volume batch-processing manufacturing is utilized, with package and resonator assembly at the wafer level. Unique design features include squeeze-film damping for robust vibration and shock performance, capacitive coupling through micro-machined diaphragms allowing resonator excitation at the package exterior, circuit integration and extremely small (0.1 in. square) dimensioning. A family of micro-miniature sensor beacons is also disclosed with widespread applications as bio-medical sensors, vehicle status monitors and high-volume animal identification and health sensors. The sensor family allows measurement of temperatures, chemicals, acceleration and pressure. A microphone and clock realization is also available. 21 figs.

  3. Multinuclear nanoliter one-dimensional and two-dimensional NMR spectroscopy with a single non-resonant microcoil

    NASA Astrophysics Data System (ADS)

    Fratila, Raluca M.; Gomez, M. Victoria; Sýkora, Stanislav; Velders, Aldrik H.

    2014-01-01

    Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical technique, but its low sensitivity and highly sophisticated, costly, equipment severely constrain more widespread applications. Here we show that a non-resonant planar transceiver microcoil integrated in a microfluidic chip (detection volume 25 nl) can detect different nuclides in the full broad-band range of Larmor frequencies (at 9.4 T from 61 to 400 MHz). Routine one-dimensional (1D) and two-dimensional (2D), homo- and heteronuclear experiments can be carried out using the broad-band coil set-up. Noteworthy, heteronuclear 2D experiments can be performed in a straightforward manner on virtually any combination of nuclides (from classical 1H-13C to more exotic combinations like 19F-31P) both in coupled and decoupled mode. Importantly, the concept of a non-resonant system provides magnetic field-independent NMR probes; moreover, the small-volume alleviates problems related to field inhomogeneity, making the broad-band coil an attractive option for, for example, portable and table-top NMR systems.

  4. Comparison of detectability in step-and-shoot mode and continuous mode digital tomosynthesis systems

    NASA Astrophysics Data System (ADS)

    Lee, Changwoo; Han, Minah; Baek, Jongduk

    2017-03-01

    Digital tomosynthesis system has been widely used in chest, dental, and breast imaging. Since the digital tomosynthesis system provides volumetric images from multiple projection data, structural noise inherent in X-ray radiograph can be reduced, and thus signal detection performance is improved. Currently, tomosynthesis system uses two data acquisition modes: step-and-shoot mode and continuous mode. Several studies have been conducted to compare the system performance of two acquisition modes with respect to spatial resolution and contrast. In this work, we focus on signal detectability in step-and-shoot mode and continuous mode. For evaluation, uniform background is considered, and eight spherical objects with diameters of 0.5, 0.8, 1, 2, 3, 5, 8, 10 mm are used as signals. Projection data with and without spherical objects are acquired in step-and-shoot mode and continuous mode, respectively, and quantum noise are added. Then, noisy projection data are reconstructed by FDK algorithm. To compare the detection performance of two acquisition modes, we calculate task signal-to-noise ratio (SNR) of channelized Hotelling observer with Laguerre-Gauss channels for each spherical object. While the task-SNR values of two acquisition modes are similar for spherical objects larger than 1 mm diameter, step-and-shoot mode yields higher detectability for small signal sizes. The main reason of this behavior is that small signal is more affected by X-ray tube motion blur than large signal. Our results indicate that it is beneficial to use step-and-shoot data acquisition mode to improve the detectability of small signals (i.e., less than 1 mm diameter) in digital tomosynthesis systems.

  5. The TMI regenerable solid oxide fuel cell

    NASA Technical Reports Server (NTRS)

    Cable, Thomas L.

    1995-01-01

    Energy storage and production in space requires rugged, reliable hardware which minimizes weight, volume, and maintenance while maximizing power output and usable energy storage. These systems generally consist of photovoltaic solar arrays which operate during sunlight cycles to provide system power and regenerate fuel (hydrogen) via water electrolysis; during dark cycles, hydrogen is converted by the fuel cell into system. The currently preferred configuration uses two separate systems (fuel cell and electrolyzer) in conjunction with photovoltaic cells. Fuel cell/electrolyzer system simplicity, reliability, and power-to-weight and power-to-volume ratios could be greatly improved if both power production (fuel cell) and power storage (electrolysis) functions can be integrated into a single unit. The Technology Management, Inc. (TMI), solid oxide fuel cell-based system offers the opportunity to both integrate fuel cell and electrolyzer functions into one unit and potentially simplify system requirements. Based an the TMI solid oxide fuel cell (SOPC) technology, the TMI integrated fuel cell/electrolyzer utilizes innovative gas storage and operational concepts and operates like a rechargeable 'hydrogen-oxygen battery'. Preliminary research has been completed on improved H2/H2O electrode (SOFC anode/electrolyzer cathode) materials for solid oxide, regenerative fuel cells. Improved H2/H2O electrode materials showed improved cell performance in both fuel cell and electrolysis modes in reversible cell tests. ln reversible fuel cell/electrolyzer mode, regenerative fuel cell efficiencies (ratio of power out (fuel cell mode) to power in (electrolyzer model)) improved from 50 percent (using conventional electrode materials) to over 80 percent. The new materials will allow the TMI SOFC system to operate as both the electrolyzer and fuel cell in a single unit. Preliminary system designs have also been developed which indicate the technical feasibility of using the TMI SOFC technology for space applications with high energy storage efficiencies and high specific energy. Development of small space systems would also have potential dual-use, terrestrial applications.

  6. The TMI regenerable solid oxide fuel cell

    NASA Astrophysics Data System (ADS)

    Cable, Thomas L.

    1995-04-01

    Energy storage and production in space requires rugged, reliable hardware which minimizes weight, volume, and maintenance while maximizing power output and usable energy storage. These systems generally consist of photovoltaic solar arrays which operate during sunlight cycles to provide system power and regenerate fuel (hydrogen) via water electrolysis; during dark cycles, hydrogen is converted by the fuel cell into system. The currently preferred configuration uses two separate systems (fuel cell and electrolyzer) in conjunction with photovoltaic cells. Fuel cell/electrolyzer system simplicity, reliability, and power-to-weight and power-to-volume ratios could be greatly improved if both power production (fuel cell) and power storage (electrolysis) functions can be integrated into a single unit. The Technology Management, Inc. (TMI), solid oxide fuel cell-based system offers the opportunity to both integrate fuel cell and electrolyzer functions into one unit and potentially simplify system requirements. Based an the TMI solid oxide fuel cell (SOPC) technology, the TMI integrated fuel cell/electrolyzer utilizes innovative gas storage and operational concepts and operates like a rechargeable 'hydrogen-oxygen battery'. Preliminary research has been completed on improved H2/H2O electrode (SOFC anode/electrolyzer cathode) materials for solid oxide, regenerative fuel cells. Improved H2/H2O electrode materials showed improved cell performance in both fuel cell and electrolysis modes in reversible cell tests. ln reversible fuel cell/electrolyzer mode, regenerative fuel cell efficiencies (ratio of power out (fuel cell mode) to power in (electrolyzer model)) improved from 50 percent (using conventional electrode materials) to over 80 percent. The new materials will allow the TMI SOFC system to operate as both the electrolyzer and fuel cell in a single unit. Preliminary system designs have also been developed which indicate the technical feasibility of using the TMI SOFC technology for space applications with high energy storage efficiencies and high specific energy. Development of small space systems would also have potential dual-use, terrestrial applications.

  7. Projected Demand and Potential Impacts to the National Airspace System of Autonomous, Electric, On-Demand Small Aircraft

    NASA Technical Reports Server (NTRS)

    Smith, Jeremy C.; Viken, Jeffrey K.; Guerreiro, Nelson M.; Dollyhigh, Samuel M.; Fenbert, James W.; Hartman, Christopher L.; Kwa, Teck-Seng; Moore, Mark D.

    2012-01-01

    Electric propulsion and autonomy are technology frontiers that offer tremendous potential to achieve low operating costs for small-aircraft. Such technologies enable simple and safe to operate vehicles that could dramatically improve regional transportation accessibility and speed through point-to-point operations. This analysis develops an understanding of the potential traffic volume and National Airspace System (NAS) capacity for small on-demand aircraft operations. Future demand projections use the Transportation Systems Analysis Model (TSAM), a tool suite developed by NASA and the Transportation Laboratory of Virginia Polytechnic Institute. Demand projections from TSAM contain the mode of travel, number of trips and geographic distribution of trips. For this study, the mode of travel can be commercial aircraft, automobile and on-demand aircraft. NASA's Airspace Concept Evaluation System (ACES) is used to assess NAS impact. This simulation takes a schedule that includes all flights: commercial passenger and cargo; conventional General Aviation and on-demand small aircraft, and operates them in the simulated NAS. The results of this analysis projects very large trip numbers for an on-demand air transportation system competitive with automobiles in cost per passenger mile. The significance is this type of air transportation can enhance mobility for communities that currently lack access to commercial air transportation. Another significant finding is that the large numbers of operations can have an impact on the current NAS infrastructure used by commercial airlines and cargo operators, even if on-demand traffic does not use the 28 airports in the Continental U.S. designated as large hubs by the FAA. Some smaller airports will experience greater demand than their current capacity allows and will require upgrading. In addition, in future years as demand grows and vehicle performance improves other non-conventional facilities such as short runways incorporated into shopping mall or transportation hub parking areas could provide additional capacity and convenience.

  8. Modeling for Matrix Multicracking Evolution of Cross-ply Ceramic-Matrix Composites Using Energy Balance Approach

    NASA Astrophysics Data System (ADS)

    Longbiao, Li

    2015-12-01

    The matrix multicracking evolution of cross-ply ceramic-matrix composites (CMCs) has been investigated using energy balance approach. The multicracking of cross-ply CMCs was classified into five modes, i.e., (1) mode 1: transverse multicracking; (2) mode 2: transverse multicracking and matrix multicracking with perfect fiber/matrix interface bonding; (3) mode 3: transverse multicracking and matrix multicracking with fiber/matrix interface debonding; (4) mode 4: matrix multicracking with perfect fiber/matrix interface bonding; and (5) mode 5: matrix multicracking with fiber/matrix interface debonding. The stress distributions of four cracking modes, i.e., mode 1, mode 2, mode 3 and mode 5, are analysed using shear-lag model. The matrix multicracking evolution of mode 1, mode 2, mode 3 and mode 5, has been determined using energy balance approach. The effects of ply thickness and fiber volume fraction on matrix multicracking evolution of cross-ply CMCs have been investigated.

  9. How To Set Up Your Own Small Business. Volumes I-II and Overhead Transparencies.

    ERIC Educational Resources Information Center

    Fallek, Max

    This two-volume textbook and collection of overhead transparency masters is intended for use in a course in setting up a small business. The following topics are covered in the first volume: getting off to a good start, doing market research, forecasting sales, financing a small business, understanding the different legal needs of different types…

  10. Volume estimation of small phantoms and rat kidneys using three-dimensional ultrasonography and a position sensor.

    PubMed

    Strømmen, Kenneth; Stormark, Tor André; Iversen, Bjarne M; Matre, Knut

    2004-09-01

    To evaluate the accuracy of small volume estimation, both in vivo and in vitro, measurements with a three-dimensional (3D) ultrasound (US) system were carried out. A position sensor was used and the transmitting frequency was 10 MHz. Balloons with known volumes were scanned while rat kidneys were scanned in vivo and in vitro. The Archimedes' principle was used to estimate the true volume. For balloons, the 3D US system gave very good agreement with true volumes in the volume range 0.1 to 10.0 mL (r = 0.999, n = 45, mean difference +/- 2SD = 0.245 +/- 0.370 mL). For rat kidneys in vivo (volume range 0.6 to 2.7 mL) the method was less accurate (r = 0.800, n = 10, mean difference +/- 2SD = -0.288 +/- 0.676 mL). For rat kidneys in vitro (volume range 0.3 to 2.7 mL) the results showed good agreement (r = 0.981, n = 23, mean difference +/- 2SD = 0.039 +/- 0.254 mL). For balloons, kidneys in vivo and in vitro, the mean percentage error was 9.3 +/- 4.8%, -17.1 +/- 17.4%, and 4.6 +/- 11.5%, respectively. This method can estimate the volume of small phantoms and rat kidneys and opens new possibilities for volume measurements of small objects and the study of organ function in small animals. (E-mail ).

  11. Longitudinal mode selection in a delay-line homogeneously broadened oscillator with a fast saturable amplifier.

    PubMed

    Fleyer, Michael; Horowitz, Moshe

    2017-05-01

    Homogeneously broadened delay-line oscillators such as lasers or optoelectronic oscillators (OEOs) can potentially oscillate in a large number of cavity modes that are supported by their amplifier bandwidth. In a continuous wave operating mode, the oscillating mode is selected between one or few cavity modes that experience the highest small-signal gain. In this manuscript, we show that the oscillation mode of a homogeneously broadened oscillator can be selected from a large number of modes in a frequency region that can be broader than the full width at half maximum of the effective cavity filter. The mode is selected by a short-time injection of an external signal into the oscillator. After the external signal is turned off, the oscillation is maintained in the selected mode even if this mode has a significantly lower small-signal gain than that of other cavity modes. The stability of the oscillation is obtained due to nonlinear saturation effect in the oscillator amplifier. We demonstrate, experimentally and theoretically, mode selection in a long cavity OEO. We could select any desired mode between 400 cavity modes while maintaining ultra-low phase noise in the selected mode and in the non-oscillating modes. No mode-hopping was observed during our maximum measurement duration of about 24 hours.

  12. List mode multichannel analyzer

    DOEpatents

    Archer, Daniel E [Livermore, CA; Luke, S John [Pleasanton, CA; Mauger, G Joseph [Livermore, CA; Riot, Vincent J [Berkeley, CA; Knapp, David A [Livermore, CA

    2007-08-07

    A digital list mode multichannel analyzer (MCA) built around a programmable FPGA device for onboard data analysis and on-the-fly modification of system detection/operating parameters, and capable of collecting and processing data in very small time bins (<1 millisecond) when used in histogramming mode, or in list mode as a list mode MCA.

  13. Polar organic compounds in pore waters of the Chesapeake Bay impact structure, Eyreville core hole: Character of the dissolved organic carbon and comparison with drilling fluids

    USGS Publications Warehouse

    Rostad, C.E.; Sanford, W.E.

    2009-01-01

    Pore waters from the Chesapeake Bay impact structure cores recovered at Eyreville Farm, Northampton County, Virginia, were analyzed to characterize the dissolved organic carbon. After squeezing or centrifuging, a small volume of pore water, 100 ??L, was taken for analysis by electrospray ionization-mass spectrometry. Porewater samples were analyzed directly without filtration or fractionation, in positive and negative mode, for polar organic compounds. Spectra in both modes were dominated by low-molecular-weight ions. Negative mode had clusters of ions differing by -60 daltons, possibly due to increasing concentrations of inorganic salts. The numberaverage molecular weight and weight-average molecular weight values for the pore waters from the Chesapeake Bay impact structure are higher than those reported for other aquatic sources of natural dissolved organic carbon as determined by electrospray ionization-mass spectrometry. In order to address the question of whether drilling mud fluids may have contaminated the pore waters during sample collection, spectra from the pore waters were compared to spectra from drilling mud fluids. Ions indicative of drilling mud fluids were not found in spectra from the pore waters, indicating there was no detectable contamination, and highlighting the usefulness of this analytical technique for detecting potential contamination during sample collection. ?? 2009 The Geological Society of America.

  14. An Ultra-Sensitive Method for the Analysis of Perfluorinated ...

    EPA Pesticide Factsheets

    In epidemiological research, it has become increasingly important to assess subjects' exposure to different classes of chemicals in multiple environmental media. It is a common practice to aliquot limited volumes of samples into smaller quantities for specific trace level chemical analysis. A novel method was developed for the determination of 14 perfluorinated alkyl acids (PFAAs) in small volumes (10 mL) of drinking water using off-line solid phase extraction (SPE) pre-treatment followed by on-line pre-concentration on WAX column before analysis on column-switching high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS). In general, large volumes (100 - 1000 mL) have been used for the analysis of PFAAs in drinking water. The current method requires approximately 10 mL of drinking water concentrated by using an SPE cartridge and eluted with methanol. A large volume injection of the extract was introduced on to a column-switching HPLC-MS/MS using a mix-mode SPE column for the trace level analysis of PFAAs in water. The recoveries for most of the analytes in the fortified laboratory blanks ranged from 73±14% to 128±5%. The lowest concentration minimum reporting levels (LCMRL) for the 14 PFAAs ranged from 0.59 to 3.4 ng/L. The optimized method was applied to a pilot-scale analysis of a subset of drinking water samples from an epidemiological study. These samples were collected directly from the taps in the households of Ohio and Nor

  15. Small tractors for harvesting fuelwood in low-volume small-diameter hardwood stands

    Treesearch

    Neil K. Huyler; Chris B. LeDoux

    1989-01-01

    Much of the nonindustrial, private forest land in the Northeast is characterized by small diameter trees with low volume. Conventional harvesting systems used in logging these stands generally results in submarginal economic returns. Often, small-scale harvesting systems have economic advantages in these areas. Time and motion studies were conducted for several small...

  16. Propulsion and airframe aerodynamic interactions of supersonic V/STOL configurations. Volume 1: Wind tunnel test pressure data report

    NASA Technical Reports Server (NTRS)

    Zilz, D. E.; Devereaux, P. A.

    1985-01-01

    A wind tunnel model of a supersonic V/STOL fighter configuration has been tested to measure the aerodynamic interaction effects which can result from geometrically close-coupled propulsion system/airframe components. The approach was to configure the model to represent two different test techniques. One was a conventional test technique composed of two test modes. In the Flow-Through mode, absolute configuration aerodynamics are measured, including inlet/airframe interactions. In the Jet-Effects mode, incremental nozzle/airframe interactions are measured. The other test technique is a propulsion simulator approach, where a sub-scale, externally powered engine is mounted in the model. This allows proper measurement of inlet/airframe and nozzle/airframe interactions simultaneously. This is Volume 1 of 2: Wind Tunnel Test Pressure Data Report.

  17. Method for preparing small volume reaction containers

    DOEpatents

    Retterer, Scott T.; Doktycz, Mitchel J.

    2017-04-25

    Engineered reaction containers that can be physically and chemically defined to control the flux of molecules of different sizes and charge are disclosed. Methods for constructing small volume reaction containers through a combination of etching and deposition are also disclosed. The methods allow for the fabrication of multiple devices that possess features on multiple length scales, specifically small volume containers with controlled porosity on the nanoscale.

  18. Component mode synthesis and large deflection vibration of complex structures. Volume 3: Multiple-mode nonlinear free and forced vibrations of beams using finite element method

    NASA Technical Reports Server (NTRS)

    Mei, Chuh; Shen, Mo-How

    1987-01-01

    Multiple-mode nonlinear forced vibration of a beam was analyzed by the finite element method. Inplane (longitudinal) displacement and inertia (IDI) are considered in the formulation. By combining the finite element method and nonlinear theory, more realistic models of structural response are obtained more easily and faster.

  19. Initial clinical observations of intra- and interfractional motion variation in MR-guided lung SBRT.

    PubMed

    Thomas, David H; Santhanam, Anand; Kishan, Amar U; Cao, Minsong; Lamb, James; Min, Yugang; O'Connell, Dylan; Yang, Yingli; Agazaryan, Nzhde; Lee, Percy; Low, Daniel

    2018-02-01

    To evaluate variations in intra- and interfractional tumour motion, and the effect on internal target volume (ITV) contour accuracy, using deformable image registration of real-time two-dimensional-sagittal cine-mode MRI acquired during lung stereotactic body radiation therapy (SBRT) treatments. Five lung tumour patients underwent free-breathing SBRT treatments on the ViewRay system, with dose prescribed to a planning target volume (defined as a 3-6 mm expansion of the 4DCT-ITV). Sagittal slice cine-MR images (3.5 × 3.5 mm 2 pixels) were acquired through the centre of the tumour at 4 frames per second throughout the treatments (3-4 fractions of 21-32 min). Tumour gross tumour volumes (GTVs) were contoured on the first frame of the MR cine and tracked for the first 20 min of each treatment using offline optical-flow based deformable registration implemented on a GPU cluster. A ground truth ITV (MR-ITV 20 min ) was formed by taking the union of tracked GTV contours. Pseudo-ITVs were generated from unions of the GTV contours tracked over 10 s segments of image data (MR-ITV 10 s ). Differences were observed in the magnitude of median tumour displacement between days of treatments. MR-ITV 10 s areas were as small as 46% of the MR-ITV 20 min . An ITV offers a "snapshot" of breathing motion for the brief period of time the tumour is imaged on a specific day. Real-time MRI over prolonged periods of time and over multiple treatment fractions shows that ITV size varies. Further work is required to investigate the dosimetric effect of these results. Advances in knowledge: Five lung tumour patients underwent free-breathing MRI-guided SBRT treatments, and their tumours tracked using deformable registration of cine-mode MRI. The results indicate that variability of both intra- and interfractional breathing amplitude should be taken into account during planning of lung radiotherapy.

  20. Five-dimensional ultrasound system for soft tissue visualization.

    PubMed

    Deshmukh, Nishikant P; Caban, Jesus J; Taylor, Russell H; Hager, Gregory D; Boctor, Emad M

    2015-12-01

    A five-dimensional ultrasound (US) system is proposed as a real-time pipeline involving fusion of 3D B-mode data with the 3D ultrasound elastography (USE) data as well as visualization of these fused data and a real-time update capability over time for each consecutive scan. 3D B-mode data assist in visualizing the anatomy of the target organ, and 3D elastography data adds strain information. We investigate the feasibility of such a system and show that an end-to-end real-time system, from acquisition to visualization, can be developed. We present a system that consists of (a) a real-time 3D elastography algorithm based on a normalized cross-correlation (NCC) computation on a GPU; (b) real-time 3D B-mode acquisition and network transfer; (c) scan conversion of 3D elastography and B-mode volumes (if acquired by 4D wobbler probe); and (d) visualization software that fuses, visualizes, and updates 3D B-mode and 3D elastography data in real time. We achieved a speed improvement of 4.45-fold for the threaded version of the NCC-based 3D USE versus the non-threaded version. The maximum speed was 79 volumes/s for 3D scan conversion. In a phantom, we validated the dimensions of a 2.2-cm-diameter sphere scan-converted to B-mode volume. Also, we validated the 5D US system visualization transfer function and detected 1- and 2-cm spherical objects (phantom lesion). Finally, we applied the system to a phantom consisting of three lesions to delineate the lesions from the surrounding background regions of the phantom. A 5D US system is achievable with real-time performance. We can distinguish between hard and soft areas in a phantom using the transfer functions.

  1. Superconducting multi-cell trapped mode deflecting cavity

    DOEpatents

    Lunin, Andrei; Khabiboulline, Timergali; Gonin, Ivan; Yakovlev, Vyacheslav; Zholents, Alexander

    2017-10-10

    A method and system for beam deflection. The method and system for beam deflection comprises a compact superconducting RF cavity further comprising a waveguide comprising an open ended resonator volume configured to operate as a trapped dipole mode; a plurality of cells configured to provide a high operating gradient; at least two pairs of protrusions configured for lowering surface electric and magnetic fields; and a main power coupler positioned to optimize necessary coupling for an operating mode and damping lower dipole modes simultaneously.

  2. Small Business Management and Ownership. Volume Four. Mini-Problems in Entrepreneurship.

    ERIC Educational Resources Information Center

    Shuchat, Jo

    The mini-problems presented in this volume are provided to augment the introductory course, "Minding Your Own Small Business," and the advanced course, "Something Ventured, Something Gained," in small business ownership and management. They can also be used in conjunction with other instructional materials in small business…

  3. Forced and intrinsic variability in the response to increased wind stress of an idealized Southern Ocean

    NASA Astrophysics Data System (ADS)

    Wilson, Chris; Hughes, Chris W.; Blundell, Jeffrey R.

    2015-01-01

    use ensemble runs of a three layer, quasi-geostrophic idealized Southern Ocean model to explore the roles of forced and intrinsic variability in response to a linear increase of wind stress imposed over a 30 year period. We find no increase of eastward circumpolar volume transport in response to the increased wind stress. A large part of the resulting time series can be explained by a response in which the eddy kinetic energy is linearly proportional to the wind stress with a possible time lag, but no statistically significant lag is found. However, this simple relationship is not the whole story: several intrinsic time scales also influence the response. We find an e-folding time scale for growth of small perturbations of 1-2 weeks. The energy budget for intrinsic variability at periods shorter than a year is dominated by exchange between kinetic and potential energy. At longer time scales, we find an intrinsic mode with period in the region of 15 years, which is dominated by changes in potential energy and frictional dissipation in a manner consistent with that seen by Hogg and Blundell (2006). A similar mode influences the response to changing wind stress. This influence, robust to perturbations, is different from the supposed linear relationship between wind stress and eddy kinetic energy, and persists for 5-10 years in this model, suggestive of a forced oscillatory mode with period of around 15 years. If present in the real ocean, such a mode would imply a degree of predictability of Southern Ocean dynamics on multiyear time scales.

  4. Gas-enabled resonance and rectified motion of a piston in a vibrated housing filled with a viscous liquid

    DOE PAGES

    Romero, Louis A.; Torczynski, John R.; Clausen, Jonathan R.; ...

    2015-11-16

    Herein, we show how introducing a small amount of gas can completely change the motion of a solid object in a viscous liquid during vibration. We analyze an idealized system exhibiting this behavior: a piston moving in a liquid-filled housing, where the gaps between the piston and the housing are narrow and depend on the piston position. Recent experiments have shown that vibration causes some gas to move below the piston and the piston to subsequently move downward and compress its supporting spring. Herein, we analyze the analogous but simpler situation in which the gas regions are replaced by bellowsmore » with similar pressure-volume relationships. We show that these bellows form a spring (analogous to the pneumatic spring formed by the gas regions) which enables the piston and the liquid to oscillate in a mode that does not exist without this spring. This mode is referred to here as the Couette mode because the liquid in the gaps moves essentially in Couette flow (i.e., with almost no component of Poiseuille flow). Since Couette flow by itself produces extremely low damping, the Couette mode has a strong resonance. We show that, near this resonance, the dependence of the gap geometry on the piston position produces a large rectified (net) force on the piston during vibration. As a result, this force can be much larger than the piston weight and the strength of its supporting spring and is in the direction that decreases the flow resistance of the gap geometry.« less

  5. Modeling of a pitching and plunging airfoil using experimental flow field and load measurements

    NASA Astrophysics Data System (ADS)

    Troshin, Victor; Seifert, Avraham

    2018-01-01

    The main goal of the current paper is to outline a low-order modeling procedure of a heaving airfoil in a still fluid using experimental measurements. Due to its relative simplicity, the proposed procedure is applicable for the analysis of flow fields within complex and unsteady geometries and it is suitable for analyzing the data obtained by experimentation. Currently, this procedure is used to model and predict the flow field evolution using a small number of low profile load sensors and flow field measurements. A time delay neural network is used to estimate the flow field. The neural network estimates the amplitudes of the most energetic modes using four sensory inputs. The modes are calculated using proper orthogonal decomposition of the flow field data obtained experimentally by time-resolved, phase-locked particle imaging velocimetry. To permit the use of proper orthogonal decomposition, the measured flow field is mapped onto a stationary domain using volume preserving transformation. The analysis performed by the model showed good estimation quality within the parameter range used in the training procedure. However, the performance deteriorates for cases out of this range. This situation indicates that, to improve the robustness of the model, both the decomposition and the training data sets must be diverse in terms of input parameter space. In addition, the results suggest that the property of volume preservation of the mapping does not affect the model quality as long as the model is not based on the Galerkin approximation. Thus, it may be relaxed for cases with more complex geometry and kinematics.

  6. Creating a zero-order resonator using an optical surface transformation

    PubMed Central

    Sun, Fei; Ge, Xiaochen; He, Sailing

    2016-01-01

    A novel zero-order resonator has been designed by an optical surface transformation (OST) method. The resonator proposed here has many novel features. Firstly, the mode volume can be very small (e.g. in the subwavelength scale). Secondly, the resonator is open (no reflecting walls are utilized) and resonant effects can be found in a continuous spectrum (i.e. a continuum of eigenmodes). Thirdly, we only need one homogenous medium to realize the proposed resonator. The shape of the resonator can be a ring structure of arbitrary shape. In addition to the natural applications (e.g. optical storage) of an optical resonator, we also suggest some other applications of our novel optical open resonator (e.g. power combination, squeezing electromagnetic energy in the free space). PMID:26888359

  7. Are we fully utilizing the functionalities of modern operating room ventilators?

    PubMed

    Liu, Shujie; Kacmarek, Robert M; Oto, Jun

    2017-12-01

    The modern operating room ventilators have become very sophisticated and many of their features are comparable with those of an ICU ventilator. To fully utilize the functionality of modern operating room ventilators, it is important for clinicians to understand in depth the working principle of these ventilators and their functionalities. Piston ventilators have the advantages of delivering accurate tidal volume and certain flow compensation functions. Turbine ventilators have great ability of flow compensation. Ventilation modes are mainly volume-based or pressure-based. Pressure-based ventilation modes provide better leak compensation than volume-based. The integration of advanced flow generation systems and ventilation modes of the modern operating room ventilators enables clinicians to provide both invasive and noninvasive ventilation in perioperative settings. Ventilator waveforms can be used for intraoperative neuromonitoring during cervical spine surgery. The increase in number of new features of modern operating room ventilators clearly creates the opportunity for clinicians to optimize ventilatory care. However, improving the quality of ventilator care relies on a complete understanding and correct use of these new features. VIDEO ABSTRACT: http://links.lww.com/COAN/A47.

  8. Current Scientific Approaches to Decision Making in Complex Systems. 3. Volume 2. Conference Position Papers

    DTIC Science & Technology

    1980-01-01

    Search: Traffic on a Multi- dimensional Structure R. i. Atkin, University of Essex, England b. Annex. Volume 3: Decision: Foundation and Practice Brian R...Gaines, University of Essex, England Volume 4: Competing Modes of Cognition and Communication in Simulated and Self-Reflective Systems Stein Braten... University of Oslo, Norway Volume 5: On the Spontaneous Emergence of Decision Making Constraints in Communicating Hierarchical Structure John S

  9. Large amplitude m=1 diocotron mode measurements in the Electron Diffusion Gauge experiment

    NASA Astrophysics Data System (ADS)

    Jenkins, Thomas G.; Morrison, Kyle A.; Davidson, Ronald C.; Paul, Stephen F.

    2002-01-01

    Smaller-diameter pure electron plasmas are generated in the Electron Diffusion Gauge (EDG) using a thoriated tungsten filament wound into a spiral shape with an outer diameter which is 1/4 of the trap wall diameter. The m=1 diocotron mode is excited in the plasma by means of the resistive-wall instability, using a resistor-relay circuit which allows the mode to be induced at various initial amplitudes. The dynamics of this mode may be predicted using linear theory when the amplitude is small. However, it has been observed [e.g., Fine et al., Phys. Rev. Lett. 63, 2232 (1989)] [1] that at larger amplitudes the frequency of this mode (relative to the small-amplitude frequency) exhibits a quadratic dependence on the mode amplitude. In this paper, the frequency shift and nonlinear dynamics of the m=1 diocotron mode in the EDG device are investigated.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ma, Y; Lacroix, F; Lavallee, M

    Purpose: To evaluate the commercially released Collapsed Cone convolution-based(CCC) dose calculation module of the Elekta OncentraBrachy(OcB) treatment planning system(TPS). Methods: An allwater phantom was used to perform TG43 benchmarks with single source and seventeen sources, separately. Furthermore, four real-patient heterogeneous geometries (chestwall, lung, breast and prostate) were used. They were selected based on their clinical representativity of a class of clinical anatomies that pose clear challenges. The plans were used as is(no modification). For each case, TG43 and CCC calculations were performed in the OcB TPS, with TG186-recommended materials properly assigned to ROIs. For comparison, Monte Carlo simulation was runmore » for each case with the same material scheme and grid mesh as TPS calculations. Both modes of CCC (standard and high quality) were tested. Results: For the benchmark case, the CCC dose, when divided by that of TG43, yields hot-n-cold spots in a radial pattern. The pattern of the high mode is denser than that of the standard mode and is representative of angular dicretization. The total deviation ((hot-cold)/TG43) is 18% for standard mode and 11% for high mode. Seventeen dwell positions help to reduce “ray-effect”, with the total deviation to 6% (standard) and 5% (high), respectively. For the four patient cases, CCC produces, as expected, more realistic dose distributions than TG43. A close agreement was observed between CCC and MC for all isodose lines, from 20% and up; the 10% isodose line of CCC appears shifted compared to that of MC. The DVH plots show dose deviations of CCC from MC in small volume, high dose regions (>100% isodose). For patient cases, the difference between standard and high modes is almost undiscernable. Conclusion: OncentraBrachy CCC algorithm marks a significant dosimetry improvement relative to TG43 in real-patient cases. Further researches are recommended regarding the clinical implications of the above observations. Support provided by a CIHR grant and CCC system provided by Elekta-Nucletron.« less

  11. Wayside energy storage study. Volume 4 : dual-mode locomotive : preliminary design study

    DOT National Transportation Integrated Search

    1979-02-01

    A preliminary design study was conducted to confirm the technical viability and economic attractiveness of the dual-mode locomotive concept based on the most common U.S. road locomotive, the SD40-2. The study examined the existing characteristics of ...

  12. Experimental evidence of mobility enhancement in short-channel ultra-thin body double-gate MOSFETs by magnetoresistance technique

    NASA Astrophysics Data System (ADS)

    Chaisantikulwat, W.; Mouis, M.; Ghibaudo, G.; Cristoloveanu, S.; Widiez, J.; Vinet, M.; Deleonibus, S.

    2007-11-01

    Double-gate transistor with ultra-thin body (UTB) has proved to offer advantages over bulk device for high-speed, low-power applications. There is thus a strong need to obtain an accurate understanding of carrier transport and mobility in such device. In this work, we report for the first time an experimental evidence of mobility enhancement in UTB double-gate (DG) MOSFETs using magnetoresistance mobility extraction technique. Mobility in planar DG transistor operating in single- and double-gate mode is compared. The influence of different scattering mechanisms in the channel is also investigated by obtaining mobility values at low temperatures. The results show a clear mobility improvement in double-gate mode compared to single-gate mode mobility at the same inversion charge density. This is explained by the role of volume inversion in ultra-thin body transistor operating in DG mode. Volume inversion is found to be especially beneficial in terms of mobility gain at low-inversion densities.

  13. Airborne measurements of cloud-forming nuclei and aerosol particles in stabilized ground clouds produced by solid rocket booster firings

    NASA Technical Reports Server (NTRS)

    Hindman, E. E., II; Ala, G. G.; Parungo, F. P.; Willis, P. T.; Bendura, R. J.; Woods, D.

    1978-01-01

    Airborne measurements of cloud volumes, ice nuclei and cloud condensation nuclei, liquid particles, and aerosol particles were obtained from stabilized ground clouds (SGCs) produced by Titan 3 launches at Kennedy Space Center, 20 August and 5 September 1977. The SGCs were bright, white, cumulus clouds early in their life and contained up to 3.5 g/m3 of liquid in micron to millimeter size droplets. The measured cloud volumes were 40 to 60 cu km five hours after launch. The SGCs contained high concentrations of cloud condensation nuclei active at 0.2%, 0.5%, and 1.0% supersaturation for periods of three to five hours. The SGCs also contained high concentrations of submicron particles. Three modes existed in the particle population: a 0.05 to 0.1 micron mode composed of aluminum-containing particles, a 0.2 to 0.8 micron mode, and a 2.0 to 10 micron mode composed of particles that contained primarily aluminum.

  14. Leg muscle volume during 30-day 6-degree head-down bed rest with isotonic and isokinetic exercise training

    NASA Technical Reports Server (NTRS)

    Greenleaf, J. E.; Lee, P. L.; Ellis, S.; Selzer, R. H.; Ortendahl, D. A.

    1994-01-01

    Magnetic resonance imaging (MRI) was used to compare the effect of two modes of lower-extremity exercise training on the mass (volume) of posterior leg group (PLG) muscles (soleus, flexor hallucis longus, tibialis posterior, lateral and medial gastrocnemius, and flexor digitorum longus) on 19 men (ages 32-42 years) subjected to intense dynamic-isotonic (ITE, cycle ergometer, number of subjects (N) = 7), isokinetic (IKE, torque egrometer, N = 7), and no exercise (NOE, N = 5) training for 60 min/day during head-down bed rest (HDBR). Total volume of the PLG muscles decreased (p less than 0.05) similarly: ITE = 4.3 +/- SE 1.6%, IKE = 7.7 +/- 1.6%, and NOE = 6.3 +/- 0.8%; combined volume (N = 19) loss was 6.1 +/- 0.9%. Ranges of volume changes were 2.6% to -9.0% (ITE), -2.1% to -14.9% (IKE), and -3.4% to -8/1% (NOE). Correlation coefficients (r) of muscle volume versus thickness measured with ultrasonography were: ITE r + 0.79 (p less than 0.05), IKE r = 0.27 (not significant (NS)), and NOE r = 0.63 (NS). Leg-muscle volume and thickness were highly correlated (r = 0.79) when plasma volume was maintained during HDBR with ITE. Thus, neither intensive lower extremity ITE nor IKE training influence the normal non-exercised posterior leg muscle atrophy during HDBR. The relationship of muscle volume and thickness may depend on the mode of exercise training associated with the maintenance of plasma volume.

  15. Satellite Observations of Antarctic Sea Ice Thickness and Volume

    NASA Technical Reports Server (NTRS)

    Kurtz, Nathan; Markus, Thorsten

    2012-01-01

    We utilize satellite laser altimetry data from ICESat combined with passive microwave measurements to analyze basin-wide changes in Antarctic sea ice thickness and volume over a 5 year period from 2003-2008. Sea ice thickness exhibits a small negative trend while area increases in the summer and fall balanced losses in thickness leading to small overall volume changes. Using a five year time-series, we show that only small ice thickness changes of less than -0.03 m/yr and volume changes of -266 cu km/yr and 160 cu km/yr occurred for the spring and summer periods, respectively. The calculated thickness and volume trends are small compared to the observational time period and interannual variability which masks the determination of long-term trend or cyclical variability in the sea ice cover. These results are in stark contrast to the much greater observed losses in Arctic sea ice volume and illustrate the different hemispheric changes of the polar sea ice covers in recent years.

  16. Apparatus and method for collection and concentration of respirable particles into a small fluid volume

    DOEpatents

    Simon, Jonathan N.; Brown, Steve B.

    2002-01-01

    An apparatus and method for the collection of respirable particles and concentration of such particles into a small fluid volume. The apparatus captures and concentrates small (1-10 .mu.m) respirable particles into a sub-millileter volume of fluid. The method involves a two step operation, collection and concentration: wherein collection of particles is by a wetted surface having small vertical slits that act as capillary channels; and concentration is carried out by transfer of the collected particles to a small volume (sub-milliliter) container by centrifugal force whereby the particles are forced through the vertical slits and contact a non-wetted wall surface, and are deflected to the bottom where they are contained for analysis, such as a portable flow cytometer or a portable PCR DNA analysis system.

  17. Phonon Transport at Crystalline Si/Ge Interfaces: The Role of Interfacial Modes of Vibration

    PubMed Central

    Gordiz, Kiarash; Henry, Asegun

    2016-01-01

    We studied the modal contributions to heat conduction at crystalline Si and crystalline Ge interfaces and found that more than 15% of the interface conductance arises from less than 0.1% of the modes in the structure. Using the recently developed interface conductance modal analysis (ICMA) method along with a new complimentary methodology, we mapped the correlations between modes, which revealed that a small group of interfacial modes, which exist between 12–13 THz, exhibit extremely strong correlation with other modes in the system. It is found that these interfacial modes (e.g., modes with large eigen vectors for interfacial atoms) are enabled by the degree of anharmonicity near the interface, which is higher than in the bulk, and therefore allows this small group of modes to couple to all others. The analysis sheds light on the nature of localized vibrations at interfaces and can be enlightening for other investigations of localization. PMID:26979787

  18. Independent Orbiter Assessment (IOA): Assessment of the main propulsion subsystem FMEA/CIL, volume 3

    NASA Technical Reports Server (NTRS)

    Holden, K. A.

    1988-01-01

    The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed an analysis of the Main Propulsion System (MPS) hardware, generating draft failure modes and potential critical items. To preserve independence, this analysis was accomplished without reliance upon the results contained within the NASA FMEA/CIL documentation. The IOA results were then compared to available data from the Rockwell Downey/NASA JSC FMEA/CIL review. Volume 3 continues the presentation of IOA worksheets and includes the potential critical items list.

  19. Independent Orbiter Assessment (IOA): Assessment of the main propulsion subsystem FMEA/CIL, volume 2

    NASA Technical Reports Server (NTRS)

    Holden, K. A.

    1988-01-01

    The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed an analysis of the Main Propulsion System (MPS) hardware, generating draft failure modes and potential critical items. To preserve independence, this analysis was accomplished without reliance upon the results contained within the NASA FMEA/CIL documentation. The IOA results were than compared to available data from the Rockwell Downey/NASA JSC FMEA/CIL review. Volume 2 continues the presentation of IOA worksheets for MPS hardware items.

  20. Independent Orbiter Assessment (IOA): Assessment of the communication and tracking subsystem, volume 2

    NASA Technical Reports Server (NTRS)

    Long, W. C.

    1988-01-01

    The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed and analysis of the Communication and Tracking hardware, generating draft failure modes and potential critical items. The IOA results were then compared to the NASA FMEA/CIL baseline. A resolution of each discrepancy from the comparison is provided through additional analysis as required. This report documents the results of that comparison for the Orbiter Communication and Tracking hardware. Volume 2 continues the presentation of IOA worksheets.

  1. Independent Orbiter Assessment (IOA): Assessment of the reaction control system, volume 3

    NASA Technical Reports Server (NTRS)

    Prust, Chet D.; Hartman, Dan W.

    1988-01-01

    The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed an analysis of the aft and forward Reaction Control System (RCS) hardware and Electrical Power Distribution and Control (EPD and C), generating draft failure modes and potential critical items. The IOA results were then compared to the proposed Post 51-L NASA FMEA/CIL baseline. This report documents the results of that comparison for the Orbiter RCS hardware and EPD and C systems. Volume 3 continues the presentation of IOA worksheets.

  2. Independent Orbiter Assessment (IOA): Assessment of the reaction control system, volume 2

    NASA Technical Reports Server (NTRS)

    Prust, Chet D.; Hartman, Dan W.

    1988-01-01

    The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed an analysis of the aft and forward Reaction Control System (RCS) hardware and Electrical Power Distribution and Control (EPD and C), generating draft failure modes and potential critical items. The IOA results were then compared to the proposed Post 51-L NASA FMEA/CIL baseline. This report documents the results of that comparison for the Orbiter RCS hardware and EPD and C systems. Volume 2 continues the presentation of IOA worksheets.

  3. PRT Impact Study - Operational Phase : Volume 1. Travel Analysis.

    DOT National Transportation Integrated Search

    1979-03-01

    Part of a three-volume work, this report describes the analysis performed on travel data collected for the Pre-PRT Impact Study. The data analyzed consist of travel behavior, travel patterns, model utilization and travel costs of various modes of tra...

  4. PRT Impact Study Pre-PRT Phase : Volume 1. Travel Analysis.

    DOT National Transportation Integrated Search

    1976-03-01

    Part of a three-volume work, this report describes the analysis performed on travel data collected for the Pre-PRT Impact Study. The data analyzed consist of travel behavior, travel patterns, model utilization and travel costs of various modes of tra...

  5. On the magnon interaction in haematite. I - Magnon energy of optical mode.

    NASA Technical Reports Server (NTRS)

    Nagai, O.; Tanaka, T.; Bonavito, N. L.

    1972-01-01

    The effect of magnon interaction on the magnon energies of haematite was studied by the use of a recently developed random phase approximation. In this study, the spin Hamiltonian and the magnon energy were written in a power series of (1/S), where S denotes the magnitude of spin. It is known that the expression of magnon energy is rigorous up to the second term of this series. It is found that the optic mode energy is small if the free optic mode energy is small, which is contrary to Herbert's (1969) conclusion. This direct proportionality between the optic mode energy and the free optic mode energy was not confirmed in the higher order terms of 1/S.

  6. Orbiter subsystem hardware/software interaction analysis. Volume 8: Forward reaction control system

    NASA Technical Reports Server (NTRS)

    Becker, D. D.

    1980-01-01

    The results of the orbiter hardware/software interaction analysis for the AFT reaction control system are presented. The interaction between hardware failure modes and software are examined in order to identify associated issues and risks. All orbiter subsystems and interfacing program elements which interact with the orbiter computer flight software are analyzed. The failure modes identified in the subsystem/element failure mode and effects analysis are discussed.

  7. Erroneous cardiac ECG-gated PET list-mode trigger events can be retrospectively identified and replaced by an offline reprocessing approach: first results in rodents

    NASA Astrophysics Data System (ADS)

    Böning, Guido; Todica, Andrei; Vai, Alessandro; Lehner, Sebastian; Xiong, Guoming; Mille, Erik; Ilhan, Harun; la Fougère, Christian; Bartenstein, Peter; Hacker, Marcus

    2013-11-01

    The assessment of left ventricular function, wall motion and myocardial viability using electrocardiogram (ECG)-gated [18F]-FDG positron emission tomography (PET) is widely accepted in human and in preclinical small animal studies. The nonterminal and noninvasive approach permits repeated in vivo evaluations of the same animal, facilitating the assessment of temporal changes in disease or therapy response. Although well established, gated small animal PET studies can contain erroneous gating information, which may yield to blurred images and false estimation of functional parameters. In this work, we present quantitative and visual quality control (QC) methods to evaluate the accuracy of trigger events in PET list-mode and physiological data. Left ventricular functional analysis is performed to quantify the effect of gating errors on the end-systolic and end-diastolic volumes, and on the ejection fraction (EF). We aim to recover the cardiac functional parameters by the application of the commonly established heart rate filter approach using fixed ranges based on a standardized population. In addition, we propose a fully reprocessing approach which retrospectively replaces the gating information of the PET list-mode file with appropriate list-mode decoding and encoding software. The signal of a simultaneously acquired ECG is processed using standard MATLAB vector functions, which can be individually adapted to reliably detect the R-peaks. Finally, the new trigger events are inserted into the PET list-mode file. A population of 30 mice with various health statuses was analyzed and standard cardiac parameters such as mean heart rate (119 ms ± 11.8 ms) and mean heart rate variability (1.7 ms ± 3.4 ms) derived. These standard parameter ranges were taken into account in the QC methods to select a group of nine optimal gated and a group of eight sub-optimal gated [18F]-FDG PET scans of mice from our archive. From the list-mode files of the optimal gated group, we randomly deleted various fractions (5% to 60%) of contained trigger events to generate a corrupted group. The filter approach was capable to correct the corrupted group and yield functional parameters with no significant difference to the optimal gated group. We successfully demonstrated the potential of the fully reprocessing approach by applying it to the sub-optimal group, where the functional parameters were significantly improved after reprocessing (mean EF from 41% ± 16% to 60% ± 13%). When applied to the optimal gated group the fully reprocessing approach did not alter the functional parameters significantly (mean EF from 64% ± 8% to 64 ± 7%). This work presents methods to determine and quantify erroneous gating in small animal gated [18F]-FDG PET scans. We demonstrate the importance of a quality check for cardiac triggering contained in PET list-mode data and the benefit of optionally reprocessing the fully recorded physiological information to retrospectively modify or fully replace the cardiac triggering in PET list-mode data. We aim to provide a preliminary guideline of how to proceed in the presence of errors and demonstrate that offline reprocessing by filtering erroneous trigger events and retrospective gating by ECG processing is feasible. Future work will focus on the extension by additional QC methods, which may exploit the amplitude of trigger events and ECG signal by means of pattern recognition. Furthermore, we aim to transfer the proposed QC methods and the fully reprocessing approach to human myocardial PET/CT.

  8. Improvement of Railroad Roller Bearing Test Procedures & Development of Roller Bearing Diagnostic Techniques. Volume 1.

    DOT National Transportation Integrated Search

    1982-03-01

    Bearing defect data from 8,000 railroad roller bearings are analyzed to determine their defect modes and defect rate distributions. Cone bore growth, brinelling, and fatigue are identified as the predominant defect modes during the first 12 years of ...

  9. [Efficacy and problems of bladder volume measurement using portable three dimensional ultrasound scanning device--in particular, on measuring bladder volume lower than 100ml].

    PubMed

    Oh-Oka, Hitoshi; Nose, Ryuichiro

    2005-09-01

    Using a portable three dimensional ultrasound scanning device (The Bladder Scan BVI6100, Diagnostic Ultrasound Corporation), we examined measured values of bladder volume, especially focusing on volume lower than 100 ml. A total of 100 patients (male: 66, female: 34) were enrolled in the study. We made a comparison study between the measured value (the average of three measurements of bladder urine volume after a trial in male and female modes) using BVI6100, and the actual measured value of the sample obtained by urethral catheterization in each patient. We examined the factors which could increase the error rate. We also introduced the effective techniques to reduce measurement errors. The actual measured values in all patients correlated well with the average value of three measurements after a trial in a male mode of the BVI6100. The correlation coefficient was 0.887, the error rate was--4.6 +/- 24.5%, and the average coefficient of variation was 15.2. It was observed that the measurement result using the BVI6100 is influenced by patient side factors (extracted edges between bladder wall and urine, thickened bladder wall, irregular bladder wall, flattened rate of bladder, mistaking prostate for bladder in male, mistaking bladder for uterus in a female mode, etc.) or examiner side factors (angle between BVI and abdominal wall, compatibility between abdominal wall and ultrasound probe, controlling deflection while using probe, etc). When appropriate patients are chosen and proper measurement is performed, BVI6100 provides significantly higher accuracy in determining bladder volume, compared with existing abdominal ultrasound methods. BVI6100 is a convenient and extremely effective device also for the measurement of bladder urine over 100 ml.

  10. Small-animal CT: Its difference from, and impact on, clinical CT

    NASA Astrophysics Data System (ADS)

    Ritman, Erik L.

    2007-10-01

    For whole-body computed tomography (CT) images of small rodents, a voxel resolution of at least 10 -3 mm 3 is needed for scale-equivalence to that currently achieved in clinical CT scanners (˜1 mm 3) in adult humans. These "mini-CT" images generally require minutes rather than seconds to complete a scan. The radiation exposure resulting from these mini-CT scans, while higher than clinical CT scans, is below the level resulting in acute tissue damage. Hence, these scans are useful for performing clinical-type diagnostic and monitoring scans for animal models of disease and their response to treatment. "Micro-CT", with voxel size <10 -5 mm 3, has been useful for imaging isolated, intact organs at an almost cellular level of resolution. Micro-CT has the great advantage over traditional microscopic methods in that it generates detailed three-dimensional images in relatively large, opaque volumes such as an intact rodent heart or kidney. The radiation exposure needed in these scans results in acute tissue damage if used in living animals. Experience with micro-CT is contributing to exploration of new applications for clinical CT imaging by providing insights into different modes of X-ray image formation as follows: Spatial resolution should be sufficient to detect an individual Basic Functional Unit (BFU, the smallest collection of diverse cells, such as hepatic lobule, that behaves like the organ), which requires voxels ˜10 -3 mm 3 in volume, so that the BFUs can be counted. Contrast resolution sufficient to allow quantitation of: New microvascular growth, which manifests as increased tissue contrast due to X-ray contrast agent in those vessels' lumens during passage of injected contrast agent in blood. Impaired endothelial integrity which manifests as increased opacification and delayed washout of contrast from tissues. Discrimination of pathological accumulations of metals such as Fe and Ca, which occur in the arterial wall following hemorrhage or tissue damage. Micro-CT can also be used as a test bed for exploring the utility of several modes of X-ray image formation, such as the use of dual-energy X-ray subtraction, X-ray scatter, phase delay and refraction-based imaging for increasing the contrast amongst soft tissue components. With the recent commercial availability of high speed, multi-slice CT scanners which can be operated in dual-energy mode, some of these micro-CT scanner capabilities and insights are becoming implementable in those CT scanners. As a result, the potential diagnostic spectrum that can be addressed with those scanners is broadened considerably.

  11. Generalised ballooning theory of two-dimensional tokamak modes

    NASA Astrophysics Data System (ADS)

    Abdoul, P. A.; Dickinson, D.; Roach, C. M.; Wilson, H. R.

    2018-02-01

    In this work, using solutions from a local gyrokinetic flux-tube code combined with higher order ballooning theory, a new analytical approach is developed to reconstruct the global linear mode structure with associated global mode frequency. In addition to the isolated mode (IM), which usually peaks on the outboard mid-plane, the higher order ballooning theory has also captured other types of less unstable global modes: (a) the weakly asymmetric ballooning theory (WABT) predicts a mixed mode (MM) that undergoes a small poloidal shift away from the outboard mid-plane, (b) a relatively more stable general mode (GM) balloons on the top (or bottom) of the tokamak plasma. In this paper, an analytic approach is developed to combine these disconnected analytical limits into a single generalised ballooning theory. This is used to investigate how an IM behaves under the effect of sheared toroidal flow. For small values of flow an IM initially converts into a MM where the results of WABT are recaptured, and eventually, as the flow increases, the mode asymptotically becomes a GM on the top (or bottom) of the plasma. This may be an ingredient in models for understanding why in some experimental scenarios, instead of large edge localised modes (ELMs), small ELMs are observed. Finally, our theory can have other important consequences, especially for calculations involving Reynolds stress driven intrinsic rotation through the radial asymmetry in the global mode structures. Understanding the intrinsic rotation is significant because external torque in a plasma the size of ITER is expected to be relatively low.

  12. Derivation of linearized transfer functions for switching-mode regulations. Phase A: Current step-up and voltage step-up converters

    NASA Technical Reports Server (NTRS)

    Wong, R. C.; Owen, H. A., Jr.; Wilson, T. G.

    1981-01-01

    Small-signal models are derived for the power stage of the voltage step-up (boost) and the current step-up (buck) converters. The modeling covers operation in both the continuous-mmf mode and the discontinuous-mmf mode. The power stage in the regulated current step-up converter on board the Dynamics Explorer Satellite is used as an example to illustrate the procedures in obtaining the small-signal functions characterizing a regulated converter.

  13. Effect of Pressure Anisotropy on the m = 1 Small Wavelength Modes in Z-Pinches

    NASA Astrophysics Data System (ADS)

    Faghihi, M.

    1987-05-01

    A generalization of Freidberg's perpendicular MHD model is used to investigate the effect of pressure anisotropy on the small wavelength internal kink (m = 1) mode instability in a Z-Pinch. A normal mode analysis of perturbed motion of an incompressible, collisionless and cylindrical plasma is performed. The stability criterion is (rΣB2)' <= 0, where Σ = 1 - (P|| - P⊥)/B2. It cannot be fulfilled without violation of the fire hose stability condition Σ >= 0.

  14. Parsing partial molar volumes of small molecules: a molecular dynamics study.

    PubMed

    Patel, Nisha; Dubins, David N; Pomès, Régis; Chalikian, Tigran V

    2011-04-28

    We used molecular dynamics (MD) simulations in conjunction with the Kirkwood-Buff theory to compute the partial molar volumes for a number of small solutes of various chemical natures. We repeated our computations using modified pair potentials, first, in the absence of the Coulombic term and, second, in the absence of the Coulombic and the attractive Lennard-Jones terms. Comparison of our results with experimental data and the volumetric results of Monte Carlo simulation with hard sphere potentials and scaled particle theory-based computations led us to conclude that, for small solutes, the partial molar volume computed with the Lennard-Jones potential in the absence of the Coulombic term nearly coincides with the cavity volume. On the other hand, MD simulations carried out with the pair interaction potentials containing only the repulsive Lennard-Jones term produce unrealistically large partial molar volumes of solutes that are close to their excluded volumes. Our simulation results are in good agreement with the reported schemes for parsing partial molar volume data on small solutes. In particular, our determined interaction volumes() and the thickness of the thermal volume for individual compounds are in good agreement with empirical estimates. This work is the first computational study that supports and lends credence to the practical algorithms of parsing partial molar volume data that are currently in use for molecular interpretations of volumetric data.

  15. Comparison between Hydrogen, Methane and Ethylene Fuels in a 3-D Scramjet at Mach 8

    DTIC Science & Technology

    2016-06-24

    characteristics in air. The disadvantage of hydrogen is its low density, which is a particular problem for small vehicles with significant internal...characteristics in air. The disadvantage of hydrogen is its low density, which is a particular problem for small vehicles with significant internal volume...The low energy per unit volume of gaseous hydrogen, however, is a significant problem for small vehicles with internal volume constraints, in addition

  16. Propulsion and airframe aerodynamic interactions of supersonic V/STOL configurations. Volume 2: Wind tunnel test force and moment data report

    NASA Technical Reports Server (NTRS)

    Zilz, D. E.

    1985-01-01

    A wind tunnel model of a supersonic V/STOL fighter configuration has been tested to measure the aerodynamic interaction effects which can result from geometrically close-coupled propulsion system/airframe components. The approach was to configure the model to represent two different test techniques. One was a conventional test technique composed of two test modes. In the Flow-Through mode, absolute configuration aerodynamics are measured, including inlet/airframe interactions. In the Jet-Effects mode, incremental nozzle/airframe interactions are measured. The other test technique is a propulsion simulator approach, where a sub-scale, externally powered engine is mounted in the model. This allows proper measurement of inlet/airframe and nozzle/airframe interactions simultaneously. This is Volume 2 of 2: Wind Tunnel Test Force and Moment Data Report.

  17. Brain tissue volumes in the general elderly population. The Rotterdam Scan Study.

    PubMed

    Ikram, M Arfan; Vrooman, Henri A; Vernooij, Meike W; van der Lijn, Fedde; Hofman, Albert; van der Lugt, Aad; Niessen, Wiro J; Breteler, Monique M B

    2008-06-01

    We investigated how volumes of cerebrospinal fluid (CSF), grey matter (GM) and white matter (WM) varied with age, sex, small vessel disease and cardiovascular risk factors in the Rotterdam Scan Study. Participants (n=490; 60-90 years) were non-demented and 51.0% had hypertension, 4.9% had diabetes mellitus, 17.8% were current smoker and 54.0% were former smoker. We segmented brain MR-images into GM, normal WM, white matter lesion (WML) and CSF. Brain infarcts were rated visually. Volumes were expressed as percentage of intra-cranial volume. With increasing age, volumes of total brain, normal WM and total WM decreased; that of GM remained unchanged; and that of WML increased, in both men and women. Excluding persons with infarcts did not alter these results. Persons with larger load of small vessel disease had smaller brain volume, especially normal WM volume. Diastolic blood pressure, diabetes mellitus and current smoking were also related to smaller brain volume. In the elderly, higher age, small vessel disease and cardiovascular risk factors are associated with smaller brain volume, especially WM volume.

  18. Coherent nonlinear coupling between a long-wavelength mode and small-scale turbulence in the TEXT tokamak

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tsui, H.Y.W.; Rypdal, K.; Ritz, C.P.

    1993-04-26

    Bispectral analysis of Langmuir probe data indicates that coherent nonlinear coupling, in addition to the noncoherent turbulent interactions, exists in the edge plasma of the tokamak TEXT. Not all the modes involved reside within the spectral region of the usual broadband turbulence. At a major resonant surface the small-scale turbulent activity interacts [ital coherently] with a localized long-wavelength mode; a signature of regular or coherent structure. By the observed coupling to the transport related turbulence, the long-wavelength mode can influence plasma confinement indirectly. These observations signify the influence of low-order resonant surfaces on the edge turbulence in tokamaks.

  19. Tailoring light-matter coupling in semiconductor and hybrid-plasmonic nanowires

    PubMed Central

    Piccione, Brian; Aspetti, Carlos O.; Cho, Chang-Hee; Agarwal, Ritesh

    2014-01-01

    Understanding interactions between light and matter is central to many fields, providing invaluable insights into the nature of matter. In its own right, a greater understanding of light-matter coupling has allowed for the creation of tailored applications, resulting in a variety of devices such as lasers, switches, sensors, modulators, and detectors. Reduction of optical mode volume is crucial to enhancing light-matter coupling strength, and among solid-state systems, self-assembled semiconductor and hybrid-plasmonic nanowires are amenable to creation of highly-confined optical modes. Following development of unique spectroscopic techniques designed for the nanowire morphology, carefully engineered semiconductor nanowire cavities have recently been tailored to enhance light-matter coupling strength in a manner previously seen in optical microcavities. Much smaller mode volumes in tailored hybrid-plasmonic nanowires have recently allowed for similar breakthroughs, resulting in sub-picosecond excited-state lifetimes and exceptionally high radiative rate enhancement. Here, we review literature on light-matter interactions in semiconductor and hybrid-plasmonic monolithic nanowire optical cavities to highlight recent progress made in tailoring light-matter coupling strengths. Beginning with a discussion of relevant concepts from optical physics, we will discuss how our knowledge of light-matter coupling has evolved with our ability to produce ever-shrinking optical mode volumes, shifting focus from bulk materials to optical microcavities, before moving on to recent results obtained from semiconducting nanowires. PMID:25093385

  20. High pressure behavior of complex phosphate K2Ce[PO4]2: Grüneisen parameter and anharmonicity properties

    NASA Astrophysics Data System (ADS)

    Mishra, Karuna Kara; Bevara, Samatha; Ravindran, T. R.; Patwe, S. J.; Gupta, Mayanak K.; Mittal, Ranjan; Krishnan, R. Venkata; Achary, S. N.; Tyagi, A. K.

    2018-02-01

    Herein we reported structural stability, vibrational and thermal properties of K2Ce[PO4]2, a relatively underexplored complex phosphate of tetravalent Ce4+ from in situ high-pressure Raman spectroscopic investigations up to 28 GPa using a diamond anvil cell. The studies identified the soft phonons that lead to a reversible phase transformation above 8 GPa, and a phase coexistence of ambient (PI) and high pressure (PII) phases in a wider pressure region 6-11 GPa. From a visual representation of the computed eigen vector displacements, the Ag soft mode at 82 cm-1 is assigned as a lattice mode of K+ cation. Pressure-induced positional disorder is apparent from the substantial broadening of internal modes and the disappearance of low frequency lattice and external modes in phase PII above 18 GPa. Isothermal mode Grüneisen parameters γi of the various phonon modes are calculated and compared for several modes. Using these values, thermal properties such as average Grüneisen parameter, and thermal expansion coefficient are estimated as 0.47, and 2.5 × 10-6 K-1, respectively. The specific heat value was estimated from all optical modes obtained from DFT calculations as 314 J-mol-1 K-1. Our earlier reported temperature dependence of phonon frequencies is used to decouple the "true anharmonic" (explicit contribution at constant volume) and "quasi harmonic" (implicit contribution brought out by volume change) contributions from the total anharmonicity. In addition to the 81 cm-1 Ag lattice mode, several other lattice and external modes of PO43- ions are found to be strongly anharmonic.

  1. Fungi and wind strongly influence the temporal availability of logs in an old-growth spruce forest.

    PubMed

    Edman, Mattias; Jönsson, Mari; Jonsson, Bengt Gunnar

    2007-03-01

    Coarse woody debris (CWD) is a key habitat for many species in forest ecosystems. To ensure the long-term survival of such species, forest management regimes must include measures that promote dead wood dynamics similar to those of natural forests. Thus, information on CWD dynamics under natural conditions is required, including data pertaining to the underlying agents of disturbance. This study examines modes of mortality, decay rates, and temporal patterns in the availability of Picea abies logs in a Swedish old-growth forest affected by internal, small-scale disturbance. All 684 logs in a 6.6-ha plot were mapped and classified into one of six decay classes. Logs in the early stages of decay were examined for the presence of heart-rot fungi. Six years later all logs were re-inventoried, including newly formed logs. Matrix models based on the transition rates between decay classes showed that it took about 60 years for 90% of the logs to decay beyond class 6 (a deformed trunk with soft wood). Large logs (> 26 cm) decayed 40% more slowly than small logs (< 25 cm). The initial volume of logs was 37.6 m3/ha but increased to 44.8 m3/ha after six years. In addition, there was a large shift in the decay-class distribution. The volume of logs in early and late decay classes increased by 71% and 45%, respectively, while the volume of logs in the intermediate decay classes decreased by 32%. The fluctuations appear to result from pulses in mortality, driven by a combination of strong winds and the heart-rot fungus, Phellinus chrysoloma, which was present in more than 30% of all logs at an early stage of decay. These results show that large temporal fluctuations in dead wood also occur in the absence of large-scale disturbance, and that heart-rot fungi are important factors driving the overall dynamics of dead wood. Since many wood-inhabiting species are naturally rare and have very specific substrate demands, such temporal variability in dead wood availability may have effects on biodiversity and should be taken into account when designing small, protected forest areas.

  2. Small scale noise and wind tunnel tests of upper surface blowing nozzle flap concepts. Volume 1. Aerodynamic test results

    NASA Technical Reports Server (NTRS)

    Renselaer, D. J.; Nishida, R. S.; Wilkin, C. A.

    1975-01-01

    The results and analyses of aerodynamic and acoustic studies conducted on the small scale noise and wind tunnel tests of upper surface blowing nozzle flap concepts are presented. Various types of nozzle flap concepts were tested. These are an upper surface blowing concept with a multiple slot arrangement with seven slots (seven slotted nozzle), an upper surface blowing type with a large nozzle exit at approximately mid-chord location in conjunction with a powered trailing edge flap with multiple slots (split flow or partially slotted nozzle). In addition, aerodynamic tests were continued on a similar multi-slotted nozzle flap, but with 14 slots. All three types of nozzle flap concepts tested appear to be about equal in overall aerodynamic performance but with the split flow nozzle somewhat better than the other two nozzle flaps in the landing approach mode. All nozzle flaps can be deflected to a large angle to increase drag without significant loss in lift. The nozzle flap concepts appear to be viable aerodynamic drag modulation devices for landing.

  3. A High-Efficiency Wind Energy Harvester for Autonomous Embedded Systems

    PubMed Central

    Brunelli, Davide

    2016-01-01

    Energy harvesting is currently a hot research topic, mainly as a consequence of the increasing attractiveness of computing and sensing solutions based on small, low-power distributed embedded systems. Harvesting may enable systems to operate in a deploy-and-forget mode, particularly when power grid is absent and the use of rechargeable batteries is unattractive due to their limited lifetime and maintenance requirements. This paper focuses on wind flow as an energy source feasible to meet the energy needs of a small autonomous embedded system. In particular the contribution is on the electrical converter and system integration. We characterize the micro-wind turbine, we define a detailed model of its behaviour, and then we focused on a highly efficient circuit to convert wind energy into electrical energy. The optimized design features an overall volume smaller than 64 cm3. The core of the harvester is a high efficiency buck-boost converter which performs an optimal power point tracking. Experimental results show that the wind generator boosts efficiency over a wide range of operating conditions. PMID:26959018

  4. A High-Efficiency Wind Energy Harvester for Autonomous Embedded Systems.

    PubMed

    Brunelli, Davide

    2016-03-04

    Energy harvesting is currently a hot research topic, mainly as a consequence of the increasing attractiveness of computing and sensing solutions based on small, low-power distributed embedded systems. Harvesting may enable systems to operate in a deploy-and-forget mode, particularly when power grid is absent and the use of rechargeable batteries is unattractive due to their limited lifetime and maintenance requirements. This paper focuses on wind flow as an energy source feasible to meet the energy needs of a small autonomous embedded system. In particular the contribution is on the electrical converter and system integration. We characterize the micro-wind turbine, we define a detailed model of its behaviour, and then we focused on a highly efficient circuit to convert wind energy into electrical energy. The optimized design features an overall volume smaller than 64 cm³. The core of the harvester is a high efficiency buck-boost converter which performs an optimal power point tracking. Experimental results show that the wind generator boosts efficiency over a wide range of operating conditions.

  5. Quantitation of cocaine and cocaethylene in small volumes of rat whole blood using gas chromatography-mass spectrometry.

    PubMed

    Burdick, J D; Boni, R L; Fochtman, F W

    1997-05-01

    A simple solid phase extraction (SPE) technique combined with gas chromatography-mass spectrometry (GC/MS) operated in selected ion monitoring (SIM) mode is described for quantitation of cocaine and cocaethylene in small samples (250 microliters) of rat whole blood. Use of (N-[2H3C])-cocaine and (N-[2H3C])-cocaethylene internal standards resulted in high sensitivity and selectivity for this analytical method. Analysis was performed using a Hewlett-Packard 5890 GC equipped with a 7673A Automatic Liquid Sampler linked to a Hewlett-Packard 5972 Mass Selective Detector. Separation of analytes was accomplished on a cross-linked methyl silicone gum capillary column (Ultra 1: 12m x 0.2mm (i.d.) x 0.33 microns). Linearity was established over a wide range of concentrations (5.0-2000.0 ng ml-1) with good precision. Limits of detection (LOD) were 1.0 and 2.0 ng ml-1 for cocaine and cocaethylene, respectively. This analytical method was designed for use in pharmacokinetic experiments studying the formation of cocaethylene following ethanol pretreatment in rats administered cocaine.

  6. Current-Tunable NbTiN Coplanar Photonic Bandgap Resonators

    NASA Astrophysics Data System (ADS)

    Asfaw, A.; Sigillito, A. J.; Tyryshkin, A. M.; Lyon, S. A.

    Coplanar waveguide resonators have been used in several experimental settings, from superconducting qubits to electron spin resonance. In our particular application of electron spin resonance, these resonators provide increased sensitivity to electron spins due to the small mode volume. Experiments have shown that these resonators can be used to readout as few as 300 spins per shot. Recently, photonic bandgap resonators have been shown to extend the advantages of traditional CPW resonators by allowing spin manipulation both at microwave and radio frequencies, thereby enabling both electron and nuclear spin resonance within the same resonator. We present measurements made using photonic bandgap resonators fabricated with thin NbTiN films which demonstrate microwave tunability of the resonator by modulating the kinetic inductance of the superconductor. Driving a small direct current through the center pin of the resonator allows us to tune the resonant frequency by over 30 MHz around 6.4 GHz while maintaining a quality factor over 8000 at 4.8K. This provides fast and simple tunability of coplanar waveguide resonators and opens new possibilities for multiple frequency electron spin resonance experiments.

  7. Highly sensitive miniature fluidic flowmeter based on an FBG heated by Co2+-doped fiber.

    PubMed

    Liu, Zhengyong; Htein, Lin; Cheng, Lun-Kai; Martina, Quincy; Jansen, Rob; Tam, Hwa-Yaw

    2017-02-20

    In this paper, we present a miniature fluidic flow sensor based on a short fiber Bragg grating inscribed in a single mode fiber and heated by Co2+-doped multimode fibers. The proposed flow sensor was employed to measure the flow rates of oil and water, showing good sensitivity of 0.339 nm/(m/s) and 0.578 nm/(m/s) for water and oil, flowing at v = 0.2 m/s. The sensitivity can be increased with higher laser power launched to the Co2+-doped multimode fibers. A small flow rate of 0.005 m/s and 0.002 m/s can be distinguished for a particular phase of water or oil, respectively, at a certain laser power (i.e. ~1.43W). The flow sensor can measure volume speed up to 30 L/min, which is limited by the test rig. The experimental results show that the sensor can discriminate slight variation of flow rates as small as 0.002m/s.

  8. Craniofacioskeletal Syndrome: An X-Linked Dominant Disorder With Early Lethality in Males

    PubMed Central

    Stevenson, Roger E.; Brasington, Cam K.; Skinner, Cindy; Simensen, Richard J.; Spence, J. Edward; Kesler, Shelli; Reiss, Allan L.; Schwartz, Charles E.

    2011-01-01

    A syndrome with multisystem manifestations has been observed in three generations of a Caucasian family. The findings in seven females provide a composite clinical picture of microcephaly, short stature, small retroverted ears, full tip of the nose overhanging the columella, short philtrum, thin upper lip, soft tissue excrescences at the angle of the mouth, small mandible, small hands and feet with brachydactyly, finger V clinodactyly, flat feet, an excessive number of fingerprint arches, and mild impairment of cognitive function. Two males were more severely affected and died in the initial months of life. They showed intrauterine growth retardation, broad cranium with wide sutures and fontanelles, cardiac defects, small hands and feet with abnormal digital creases and small nails, and genital abnormalities. The affected males had low serum calcium in the neonatal period. Serum calcium, phosphorous, and parathormone levels in the females were normal. Radiographs showed cortical thickening of the long bones, underdevelopment of the frontal sinuses, narrow pelvis and hypoplasia of the middle phalanx of finger five. MRI of the brain showed slightly reduced brain volumes and an extra gyrus of the superior temporal region. X-inactivation studies showed near complete skewing in two affected females, but were not informative in three others. X-linkage as the mode of inheritance is proposed on the basis of different severity in males/females, complete skewing of X-inactivation in informative females, and a lod score (1.5) suggestive of linkage to markers in Xq26-q27. PMID:17853486

  9. A modular, programmable measurement system for physiological and spaceflight applications

    NASA Technical Reports Server (NTRS)

    Hines, John W.; Ricks, Robert D.; Miles, Christopher J.

    1993-01-01

    The NASA-Ames Sensors 2000! Program has developed a small, compact, modular, programmable, sensor signal conditioning and measurement system, initially targeted for Life Sciences Spaceflight Programs. The system consists of a twelve-slot, multi-layer, distributed function backplane, a digital microcontroller/memory subsystem, conditioned and isolated power supplies, and six application-specific, physiological signal conditioners. Each signal condition is capable of being programmed for gains, offsets, calibration and operate modes, and, in some cases, selectable outputs and functional modes. Presently, the system has the capability for measuring ECG, EMG, EEG, Temperature, Respiration, Pressure, Force, and Acceleration parameters, in physiological ranges. The measurement system makes heavy use of surface-mount packaging technology, resulting in plug in modules sized 125x55 mm. The complete 12-slot system is contained within a volume of 220x150x70mm. The system's capabilities extend well beyond the specific objectives of NASA programs. Indeed, the potential commercial uses of the technology are virtually limitless. In addition to applications in medical and biomedical sensing, the system might also be used in process control situations, in clinical or research environments, in general instrumentation systems, factory processing, or any other applications where high quality measurements are required.

  10. A modular, programmable measurement system for physiological and spaceflight applications

    NASA Astrophysics Data System (ADS)

    Hines, John W.; Ricks, Robert D.; Miles, Christopher J.

    1993-02-01

    The NASA-Ames Sensors 2000] Program has developed a small, compact, modular, programmable, sensor signal conditioning and measurement system, initially targeted for Life Sciences Spaceflight Programs. The system consists of a twelve-slot, multi-layer, distributed function backplane, a digital microcontroller/memory subsystem, conditioned and isolated power supplies, and six application-specific, physiological signal conditioners. Each signal condition is capable of being programmed for gains, offsets, calibration and operate modes, and, in some cases, selectable outputs and functional modes. Presently, the system has the capability for measuring ECG, EMG, EEG, Temperature, Respiration, Pressure, Force, and Acceleration parameters, in physiological ranges. The measurement system makes heavy use of surface-mount packaging technology, resulting in plug in modules sized 125x55 mm. The complete 12-slot system is contained within a volume of 220x150x70mm. The system's capabilities extend well beyond the specific objectives of NASA programs. Indeed, the potential commercial uses of the technology are virtually limitless. In addition to applications in medical and biomedical sensing, the system might also be used in process control situations, in clinical or research environments, in general instrumentation systems, factory processing, or any other applications where high quality measurements are required.

  11. Rapid determination of tafenoquine in small volume human plasma samples by high-performance liquid chromatography-tandem mass spectrometry.

    PubMed

    Doyle, E; Fowles, S E; Summerfield, S; White, T J

    2002-03-25

    A method was developed for the determination of tafenoquine (I) in human plasma using high-performance liquid chromatography-tandem mass spectrometry. Prior to analysis, the protein in plasma samples was precipitated with methanol containing [2H3(15N)]tafenoquine (II) to act as an internal standard. The supernatant was injected onto a Genesis-C18 column without any further clean-up. The mass spectrometer was operated in the positive ion mode, employing a heat assisted nebulisation, electrospray interface. Ions were detected in multiple reaction monitoring mode. The assay required 50 microl of plasma and was precise and accurate within the range 2 to 500 ng/ml. The average within-run and between-run relative standard deviations were < 7% at 2 ng/ml and greater concentrations. The average accuracy of validation standards was generally within +/- 4% of the nominal concentration. There was no evidence of instability of I in human plasma following three complete freeze-thaw cycles and samples can safely be stored for at least 8 months at approximately -70 degrees C. The method was very robust and has been successfully applied to the analysis of clinical samples from patients and healthy volunteers dosed with I.

  12. Electron kinetics in capacitively coupled plasmas modulated by electron injection

    NASA Astrophysics Data System (ADS)

    Zhang, Ya; Peng, Yanli; Innocenti, Maria Elena; Jiang, Wei; Wang, Hong-yu; Lapenta, Giovanni

    2017-09-01

    The controlling effect of an electron injection on the electron energy distribution function (EEDF) and on the energetic electron flux, in a capacitive radio-frequency argon plasma, is studied using a one-dimensional particle-in-cell/Monte Carlo collisions model. The input power of the electron beam is as small as several tens of Watts with laboratory achievable emission currents and energies. With the electron injection, the electron temperature decreases but with a significant high energy tail. The electron density, electron temperature in the sheath, and electron heating rate increase with the increasing emission energy. This is attributed to the extra heating of the energetic electrons in the EEDF tail. The non-equilibrium EEDF is obtained for strong non-local distributions of the electric field, electron heating rate, excitation, and ionization rate, indicating the discharge has transited from a volume heating (α-mode dominated) into a sheath heating (γ-mode dominated) type. In addition, the electron injection not only modifies the self-bias voltage, but also enhances the electron flux that can reach the electrodes. Moreover, the relative population of energetic electrons significantly increases with the electron injection compared to that without the electron injection, relevant for modifying the gas and surface chemistry reactions.

  13. Correction of Motion Artifacts From Shuttle Mode Computed Tomography Acquisitions for Body Perfusion Imaging Applications.

    PubMed

    Ghosh, Payel; Chandler, Adam G; Altinmakas, Emre; Rong, John; Ng, Chaan S

    2016-01-01

    The aim of this study was to investigate the feasibility of shuttle-mode computed tomography (CT) technology for body perfusion applications by quantitatively assessing and correcting motion artifacts. Noncontrast shuttle-mode CT scans (10 phases, 2 nonoverlapping bed locations) were acquired from 4 patients on a GE 750HD CT scanner. Shuttling effects were quantified using Euclidean distances (between-phase and between-bed locations) of corresponding fiducial points on the shuttle and reference phase scans (prior to shuttle mode). Motion correction with nonrigid registration was evaluated using sum-of-squares differences and distances between centers of segmented volumes of interest on shuttle and references images. Fiducial point analysis showed an average shuttling motion of 0.85 ± 1.05 mm (between-bed) and 1.18 ± 1.46 mm (between-phase), respectively. The volume-of-interest analysis of the nonrigid registration results showed improved sum-of-squares differences from 2950 to 597, between-bed distance from 1.64 to 1.20 mm, and between-phase distance from 2.64 to 1.33 mm, respectively, averaged over all cases. Shuttling effects introduced during shuttle-mode CT acquisitions can be computationally corrected for body perfusion applications.

  14. Thermodynamics of Radiation Modes

    ERIC Educational Resources Information Center

    Pina, Eduardo; de la Selva, Sara Maria Teresa

    2010-01-01

    We study the equilibrium thermodynamics of the electromagnetic radiation in a cavity of a given volume and temperature. We found three levels of description, the thermodynamics of one mode, the thermodynamics of the distribution of frequencies in a band by summing over the frequencies in it and the global thermodynamics by summing over all the…

  15. Dynamic flashing yellow arrow (FYA): a study on variable left-turn mode operational and safety impacts phase II - model expansion and testing : [summary].

    DOT National Transportation Integrated Search

    2016-05-01

    In phase two of this project, the UCF team further developed the DSS to automate selection of FYA left-turn modes based on traffic volumes at intersections acquired in real time from existing sensors.

  16. Cargo Logistics Airlift Systems Study (CLASS). Volume 2: Case study approach and results

    NASA Technical Reports Server (NTRS)

    Burby, R. J.; Kuhlman, W. H.

    1978-01-01

    Models of transportation mode decision making were developed. The user's view of the present and future air cargo systems is discussed. Issues summarized include: (1) organization of the distribution function; (2) mode choice decision making; (3) air freight system; and (4) the future of air freight.

  17. Hypersonic research engine/aerothermodynamic integration model, experimental results. Volume 2: Mach 6 performance

    NASA Technical Reports Server (NTRS)

    Andrews, E. H., Jr.; Mackley, E. A.

    1976-01-01

    Computer program performance results of a Mach 6 hypersonic research engine during supersonic and subsonic combustion modes were presented. The combustion mode transition was successfully performed, exit surveys made, and effects of altitude, angle of attack, and inlet spike position were determined during these tests.

  18. Sleeve Expansion of Bolt Holes in Railroad Rail : Volume I, Description and Planning

    DOT National Transportation Integrated Search

    1980-02-01

    The most predominant failure mode of rails with bolt joints is a web crack initiating at the rail bolt hole. This failure mode is of a classical fatigue nature induced by web stress concentration around the bolt hole. This program was conducted to ap...

  19. Airport offsite passenger service facilities : an option for improving landside access : volume 1 : definition, background, and opportunities.

    DOT National Transportation Integrated Search

    2008-01-01

    Because transportation modes are diverse, intermodal connections take several forms. They may be comprised of a major hub, such as the Virginia Inland Port, which transfers freight between the truck and rail modes, or an improvement to an existing mo...

  20. Small Power Systems Solar Electric Workshop Proceedings. Volume 1: Executive report. Volume 2: Invited papers

    NASA Technical Reports Server (NTRS)

    Ferber, R. (Editor); Evans, D. (Editor)

    1978-01-01

    The background, objectives and methodology used for the Small Power Systems Solar Electric Workshop are described, and a summary of the results and conclusions developed at the workshop regarding small solar thermal electric power systems is presented.

  1. Three-dimensional imaging of adherent cells using FIB/SEM and STEM.

    PubMed

    Villinger, Clarissa; Schauflinger, Martin; Gregorius, Heiko; Kranz, Christine; Höhn, Katharina; Nafeey, Soufi; Walther, Paul

    2014-01-01

    In this chapter we describe three different approaches for three-dimensional imaging of electron microscopic samples: serial sectioning transmission electron microscopy (TEM), scanning transmission electron microscopy (STEM) tomography, and focused ion beam/scanning electron microscopy (FIB/SEM) tomography. With these methods, relatively large volumes of resin-embedded biological structures can be analyzed at resolutions of a few nm within a reasonable expenditure of time. The traditional method is serial sectioning and imaging the same area in all sections. Another method is TEM tomography that involves tilting a section in the electron beam and then reconstruction of the volume by back projection of the images. When the scanning transmission (STEM) mode is used, thicker sections (up to 1 μm) can be analyzed. The third approach presented here is focused ion beam/scanning electron microscopy (FIB/SEM) tomography, in which a sample is repeatedly milled with a focused ion beam (FIB) and each newly produced block face is imaged with the scanning electron microscope (SEM). This process can be repeated ad libitum in arbitrary small increments allowing 3D analysis of relatively large volumes such as eukaryotic cells. We show that resolution of this approach is considerably improved when the secondary electron signal is used. However, the most important prerequisite for three-dimensional imaging is good specimen preparation. For all three imaging methods, cryo-fixed (high-pressure frozen) and freeze-substituted samples have been used.

  2. Deviation from Power Law Behavior in Landslide Phenomenon

    NASA Astrophysics Data System (ADS)

    Li, L.; Lan, H.; Wu, Y.

    2013-12-01

    Power law distribution of magnitude is widely observed in many natural hazards (e.g., earthquake, floods, tornadoes, and forest fires). Landslide is unique as the size distribution of landslide is characterized by a power law decrease with a rollover in the small size end. Yet, the emergence of the rollover, i.e., the deviation from power law behavior for small size landslides, remains a mystery. In this contribution, we grouped the forces applied on landslide bodies into two categories: 1) the forces proportional to the volume of failure mass (gravity and friction), and 2) the forces proportional to the area of failure surface (cohesion). Failure occurs when the forces proportional to volume exceed the forces proportional to surface area. As such, given a certain mechanical configuration, the failure volume to failure surface area ratio must exceed a corresponding threshold to guarantee a failure. Assuming all landslides share a uniform shape, which means the volume to surface area ratio of landslide regularly increase with the landslide volume, a cutoff of landslide volume distribution in the small size end can be defined. However, in realistic landslide phenomena, where heterogeneities of landslide shape and mechanical configuration are existent, a simple cutoff of landslide volume distribution does not exist. The stochasticity of landslide shape introduce a probability distribution of the volume to surface area ratio with regard to landslide volume, with which the probability that the volume to surface ratio exceed the threshold can be estimated regarding values of landslide volume. An experiment based on empirical data showed that this probability can induce the power law distribution of landslide volume roll down in the small size end. We therefore proposed that the constraints on the failure volume to failure surface area ratio together with the heterogeneity of landslide geometry and mechanical configuration attribute for the deviation from power law behavior in landslide phenomenon. Figure shows that a rollover of landslide size distribution in the small size end is produced as the probability for V/S (the failure volume to failure surface ratio of landslide) exceeding the mechanical threshold applied to the power law distribution of landslide volume.

  3. Numerical study on the maximum small-signal gain coefficient in passively mode-locked fiber lasers

    NASA Astrophysics Data System (ADS)

    Tang, Xin; Wang, Jian; Chen, Zhaoyang; Lin, Chengyou; Ding, Yingchun

    2017-06-01

    Ultrashort pulses have been found to have important applications in many fields, such as ultrafast diagnosis, biomedical engineering, and optical imaging. Passively mode-locked fiber lasers have become a tool for generating picosecond and femtosecond pulses. In this paper, the evolution of a picosecond laser pulse in different stable passively mode-locked fiber laser is analyzed using nonlinear Schrödinger equation. Firstly, different mode-locked regimes are calculated with different net cavity dispersion (from -0.3 ps2 to +0.3 ps2 ). Then we calculate the maximum small-signal gain on the different net cavity dispersion conditions, and estimate the pulse width, 3 dB bandwidth and time bandwidth product (TBP) when the small-signal gain coefficient is selected as the maximum value. The results show that the small signal gain coefficient is approximately proportional to the net cavity. Moreover, when the small signal gain coefficient reaches the maximum value, the pulse width of the output pulse and their corresponding TBP show a trend of increase gradually, and 3dB bandwidth shows a trend of increase firstly and then decrease. In addition, in the case that the net dispersion is positive, because of the pulse with quite large frequency chirp, the revolution to dechirp the pulse is researched and the output of the pulse is compressed and its compression ratio reached more than 10 times. The results provide a reference for the optimization of passively mode-locked fiber lasers.

  4. Future space transportation systems analysis study. Phase 1 extension: Transportation systems reference data, volume 2

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Transportation mass requirements are developed for various mission and transportation modes based on vehicle systems sized to fit the exact needs of each mission. The parametric data used to derive the mass requirements for each mission and transportation mode are presented to enable accommodation of possible changes in mode options or payload definitions. The vehicle sizing and functional requirements used to derive the parametric data are described.

  5. Analytical and experimental investigation of a 1/8-scale dynamic model of the shuttle orbiter. Volume 3B: Supporting data

    NASA Technical Reports Server (NTRS)

    Mason, P. W.; Harris, H. G.; Zalesak, J.; Bernstein, M.

    1974-01-01

    The NASA Structural Analysis System (NASTRAN) Model 1 finite element idealization, input data, and detailed analytical results are presented. The data presented include: substructuring analysis for normal modes, plots of member data, plots of symmetric free-free modes, plots of antisymmetric free-free modes, analysis of the wing, analysis of the cargo doors, analysis of the payload, and analysis of the orbiter.

  6. Interrelation of the effects caused by the rotation of the whispering gallery modes resonator

    NASA Astrophysics Data System (ADS)

    Dmitriyeva, Anna D.; Filatov, Yuri V.; Shalymov, Egor V.; Venediktov, Vladimir Yu.

    2016-11-01

    Optical whispering gallery modes resonators are characterized by unique properties: ultrahigh quality factor, small amount of the modes and small size. It allows to use them in compact high-precision measuring devices. In particular these resonators can be used in the composition of gyros. For today all researches, devoted to the application of the whispering gallery modes resonators in gyros, deals only with one of induced by the rotation effects (Sagnac effect or the influence of centrifugal forces on the resonator size). In this work we study the interrelation of the effects caused by the rotation of the whispering gallery modes resonator. Also in work we consider the possibility of joint application of both effects (the influence of centrifugal forces and Sagnac effect) for measuring angular velocity.

  7. 40 CFR 80.595 - How does a small or GPA refiner apply for a motor vehicle diesel fuel volume baseline for the...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... for a motor vehicle diesel fuel volume baseline for the purpose of extending their gasoline sulfur... a small or GPA refiner apply for a motor vehicle diesel fuel volume baseline for the purpose of... duration of the GPA standards under § 80.540 must apply for a motor vehicle diesel fuel volume baseline by...

  8. Impact of Use of Smaller Volume, Smaller Vacuum Blood Collection Tubes on Hemolysis in Emergency Department Blood Samples.

    PubMed

    Phelan, Michael P; Reineks, Edmunds Z; Berriochoa, Jacob P; Schold, Jesse D; Hustey, Fredric M; Chamberlin, Janelle; Kovach, Annmarie

    2017-10-01

    Hemolyzed blood samples commonly occur in hospital emergency departments (EDs). Our objective was to determine whether replacing standard large-volume/high-vacuum sample tubes with low-volume/low-vacuum tubes would significantly affect ED hemolysis. This was a prospective intervention of the use of small-volume/vacuum collection tubes. We evaluated all potassium samples in ED patients and associated hemolysis. We used χ2 tests to compare hemolysis incidence prior to and following utilization of small tubes for chemistry collection. There were 35,481 blood samples collected during the study period. Following implementation of small-volume tubes, overall hemolysis decreased from a baseline of 11.8% to 2.9% (P < .001) with corresponding reductions in hemolysis with comment (8.95% vs 1.99%; P < .001) gross hemolysis (2.84% vs 0.90%; P < .007). This work demonstrates that significant improvements in ED hemolysis can be achieved by utilization of small-volume/vacuum sample collection tubes. © American Society for Clinical Pathology, 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  9. Small Bowel Dose Parameters Predicting Grade ≥3 Acute Toxicity in Rectal Cancer Patients Treated With Neoadjuvant Chemoradiation: An Independent Validation Study Comparing Peritoneal Space Versus Small Bowel Loop Contouring Techniques

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Banerjee, Robyn, E-mail: robynbanerjee@gmail.com; Chakraborty, Santam; Nygren, Ian

    Purpose: To determine whether volumes based on contours of the peritoneal space can be used instead of individual small bowel loops to predict for grade ≥3 acute small bowel toxicity in patients with rectal cancer treated with neoadjuvant chemoradiation therapy. Methods and Materials: A standardized contouring method was developed for the peritoneal space and retrospectively applied to the radiation treatment plans of 67 patients treated with neoadjuvant chemoradiation therapy for rectal cancer. Dose-volume histogram (DVH) data were extracted and analyzed against patient toxicity. Receiver operating characteristic analysis and logistic regression were carried out for both contouring methods. Results: Grade ≥3more » small bowel toxicity occurred in 16% (11/67) of patients in the study. A highly significant dose-volume relationship between small bowel irradiation and acute small bowel toxicity was supported by the use of both small bowel loop and peritoneal space contouring techniques. Receiver operating characteristic analysis demonstrated that, for both contouring methods, the greatest sensitivity for predicting toxicity was associated with the volume receiving between 15 and 25 Gy. Conclusion: DVH analysis of peritoneal space volumes accurately predicts grade ≥3 small bowel toxicity in patients with rectal cancer receiving neoadjuvant chemoradiation therapy, suggesting that the contours of the peritoneal space provide a reasonable surrogate for the contours of individual small bowel loops. The study finds that a small bowel V15 less than 275 cc and a peritoneal space V15 less than 830 cc are associated with a less than 10% risk of grade ≥3 acute toxicity.« less

  10. Small-scale Pressure-balanced Structures Driven by Oblique Slow Mode Waves Measured in the Solar Wind

    NASA Astrophysics Data System (ADS)

    Yao, Shuo; He, J.-S.; Tu, C.-Y.; Wang, L.-H.; Marsch, E.

    2013-09-01

    Recently, small-scale pressure-balanced structures (PBSs) were identified in the solar wind, but their formation mechanism remains unclear. This work aims to reveal the dependence of the properties of small-scale PBSs on the background magnetic field (B 0) direction and thus to corroborate the in situ mechanism that forms them. We analyze the plasma and magnetic field data obtained by WIND in the quiet solar wind at 1 AU. First, we use a developed moving-average method to obtain B 0(s, t) for every temporal scale (s) at each time moment (t). By wavelet cross-coherence analysis, we obtain the correlation coefficients between the thermal pressure P th and the magnetic pressure P B, distributing against the temporal scale and the angle θxB between B 0(s, t) and Geocentric Solar Ecliptic coordinates (GSE)-x. We note that the angle coverage of a PBS decreases with shorter temporal scale, but the occurrence of the PBSs is independent of θxB. Suspecting that the isolated small PBSs are formed by compressive waves in situ, we continue this study by testing the wave modes forming a small-scale PBS with B 0(s, t) quasi-parallel to GSE-x. As a result, we identify that the cross-helicity and the compressibility attain values for a slow mode from theoretical calculations. The wave vector is derived from minimum variance analysis. Besides, the proton temperatures obey T < T ∥ derived from the velocity distribution functions, excluding a mirror mode, which is the other candidate for the formation of PBSs in situ. Thus, a small-scale PBS is shown to be driven by oblique, slow-mode waves in the solar wind.

  11. Mining volume measurement system

    NASA Technical Reports Server (NTRS)

    Heyman, Joseph Saul (Inventor)

    1988-01-01

    In a shaft with a curved or straight primary segment and smaller off-shooting segments, at least one standing wave is generated in the primary segment. The shaft has either an open end or a closed end and approximates a cylindrical waveguide. A frequency of a standing wave that represents the fundamental mode characteristic of the primary segment can be measured. Alternatively, a frequency differential between two successive harmonic modes that are characteristic of the primary segment can be measured. In either event, the measured frequency or frequency differential is characteristic of the length and thus the volume of the shaft based on length times the bore area.

  12. Independent Orbiter Assessment (IOA): Assessment of the main propulsion subsystem FMEA/CIL, volume 4

    NASA Technical Reports Server (NTRS)

    Slaughter, B. C.

    1988-01-01

    The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed an analysis of the Main Propulsion System (MPS) hardware, generating draft failure modes and potential critical items. To preserve independence, this analysis was accomplished without reliance upon the results contained within the NASA FMEA/CIL documentation. The IOA results were than compared to available data from the Rockwell Downey/NASA JSC FMEA/CIL review. Volume 4 contains the IOA analysis worksheets and the NASA FMEA to IOA worksheet cross reference and recommendations.

  13. Independent Orbiter Assessment (IOA): Assessment of the reaction control system, volume 4

    NASA Technical Reports Server (NTRS)

    Prust, Chet D.; Hartman, Dan W.

    1988-01-01

    The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed an analysis of the aft and forward Reaction Control System (RCS) hardware and Electrical Power Distribution and Control (EPD and C), generating draft failure modes and potential critical items. The IOA results were then compared to the proposed Post 51-L NASA FMEA/CIL baseline. This report documents the results of that comparison for the Orbiter RCS hardware and EPD and C systems. Volume 4 continues the presentation of IOA worksheets and contains the potential critical items list.

  14. Ventilation practices in the neonatal intensive care unit: a cross-sectional study.

    PubMed

    van Kaam, Anton H; Rimensberger, Peter C; Borensztajn, Dorine; De Jaegere, Anne P

    2010-11-01

    To assess current ventilation practices in newborn infants. We conducted a 2-point cross-sectional study in 173 European neonatal intensive care units, including 535 infants (mean gestational age 28 weeks and birth weight 1024 g). Patient characteristics, ventilator settings, and measurements were collected bedside from endotracheally ventilated infants. A total of 457 (85%) patients were conventionally ventilated. Time cycled pressure-limited ventilation was used in 59% of these patients, most often combined with synchronized intermittent mandatory ventilation (51%). Newer conventional ventilation modes like volume targeted and pressure support ventilation were used in, respectively, 9% and 7% of the patients. The mean tidal volume, measured in 84% of the conventionally ventilated patients, was 5.7 ± 2.3 ml/kg. The mean positive end-expiratory pressure was 4.5 ± 1.1 cmH(2)O and rarely exceeded 7 cmH(2)O. Time cycled pressure-limited ventilation is the most commonly used mode in neonatal ventilation. Tidal volumes are usually targeted between 4 to 7 mL/kg and positive end-expiratory pressure between 4 to 6 cmH(2)O. Newer ventilation modes are only used in a minority of patients. Copyright © 2010 Mosby, Inc. All rights reserved.

  15. Direct observation of isolated Damon-Eshbach and backward volume spin-wave packets in ferromagnetic microstripes

    PubMed Central

    Wessels, Philipp; Vogel, Andreas; Tödt, Jan-Niklas; Wieland, Marek; Meier, Guido; Drescher, Markus

    2016-01-01

    The analysis of isolated spin-wave packets is crucial for the understanding of magnetic transport phenomena and is particularly interesting for applications in spintronic and magnonic devices, where isolated spin-wave packets implement an information processing scheme with negligible residual heat loss. We have captured microscale magnetization dynamics of single spin-wave packets in metallic ferromagnets in space and time. Using an optically driven high-current picosecond pulse source in combination with time-resolved scanning Kerr microscopy probed by femtosecond laser pulses, we demonstrate phase-sensitive real-space observation of spin-wave packets in confined permalloy (Ni80Fe20) microstripes. Impulsive excitation permits extraction of the dynamical parameters, i.e. phase- and group velocities, frequencies and wave vectors. In addition to well-established Damon-Eshbach modes our study reveals waves with counterpropagating group- and phase-velocities. Such unusual spin-wave motion is expected for backward volume modes where the phase fronts approach the excitation volume rather than emerging out of it due to the negative slope of the dispersion relation. These modes are difficult to excite and observe directly but feature analogies to negative refractive index materials, thus enabling model studies of wave propagation inside metamaterials. PMID:26906113

  16. Dual energy CT kidney stone differentiation in photon counting computed tomography

    NASA Astrophysics Data System (ADS)

    Gutjahr, R.; Polster, C.; Henning, A.; Kappler, S.; Leng, S.; McCollough, C. H.; Sedlmair, M. U.; Schmidt, B.; Krauss, B.; Flohr, T. G.

    2017-03-01

    This study evaluates the capabilities of a whole-body photon counting CT system to differentiate between four common kidney stone materials, namely uric acid (UA), calcium oxalate monohydrate (COM), cystine (CYS), and apatite (APA) ex vivo. Two different x-ray spectra (120 kV and 140 kV) were applied and two acquisition modes were investigated. The macro-mode generates two energy threshold based image-volumes and two energy bin based image-volumes. In the chesspattern-mode four energy thresholds are applied. A virtual low energy image, as well as a virtual high energy image are derived from initial threshold-based images, while considering their statistically correlated nature. The energy bin based images of the macro-mode, as well as the virtual low and high energy image of the chesspattern-mode serve as input for our dual energy evaluation. The dual energy ratio of the individually segmented kidney stones were utilized to quantify the discriminability of the different materials. The dual energy ratios of the two acquisition modes showed high correlation for both applied spectra. Wilcoxon-rank sum tests and the evaluation of the area under the receiver operating characteristics curves suggest that the UA kidney stones are best differentiable from all other materials (AUC = 1.0), followed by CYS (AUC ≍ 0.9 compared against COM and APA). COM and APA, however, are hardly distinguishable (AUC between 0.63 and 0.76). The results hold true for the measurements of both spectra and both acquisition modes.

  17. CASIMIR Effect in a Supersymmetry-Breaking Brane-World as Dark Energy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, P

    2004-09-29

    A new model for the origin of dark energy is proposed based on the Casimir effect in a supersymmetry-breaking brane-world. Supersymmetry is assumed to be preserved in the bulk while broken on a 3-brane. Due to the boundary conditions imposed on the compactified extra dimensions, there is an effective Casimir energy induced on the brane. The net Casimir energy contributed from the graviton and the gravitino modes as a result of supersymmetry-breaking on the brane is identified as the observed dark energy, which in our construction is a cosmological constant. We show that the smallness of the cosmological constant, whichmore » results from the huge contrast in the extra-dimensional volumes between that associated with the 3-brane and that of the bulk, is attainable under very relaxed condition.« less

  18. A study of application of remote sensing to river forecasting. Volume 2: Detailed technical report, NASA-IBM streamflow forecast model user's guide

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The Model is described along with data preparation, determining model parameters, initializing and optimizing parameters (calibration) selecting control options and interpreting results. Some background information is included, and appendices contain a dictionary of variables, a source program listing, and flow charts. The model was operated on an IBM System/360 Model 44, using a model 2250 keyboard/graphics terminal for interactive operation. The model can be set up and operated in a batch processing mode on any System/360 or 370 that has the memory capacity. The model requires 210K bytes of core storage, and the optimization program, OPSET (which was used previous to but not in this study), requires 240K bytes. The data band for one small watershed requires approximately 32 tracks of disk storage.

  19. Simultaneous determination of three anticonvulsants using hydrophilic interaction LC-MS.

    PubMed

    Oertel, Reinhard; Arenz, Norman; Pietsch, Jörg; Kirch, Wilhelm

    2009-01-01

    A specific and automated method was developed to quantify the anticonvulsants gabapentin, pregabalin and vigabatrin simultaneously in human serum. Samples were prepared with a protein precipitation. The hydrophilic interaction chromatography (HILIC) with a mobile phase gradient was used to divide off ions of the matrix and for separation of the analytes. Four different HILIC-columns and two different column temperatures were tested. The Tosoh-Amid column gave the best results: single small peaks. The anticonvulsants were detected in the multiple reaction monitoring mode (MRM) with ESI-MS-MS. Using a volume of 100 microL biological sample the lowest point of the standard curve, i.e. the lower LOQs were 312 ng/mL. The described HILIC-MS-MS method is suitable for therapeutic drug monitoring and for clinical and pharmcokinetical investigations of the anticonvulsives.

  20. GASP- General Aviation Synthesis Program. Volume 1: Main program. Part 1: Theoretical development

    NASA Technical Reports Server (NTRS)

    Hague, D.

    1978-01-01

    The General Aviation synthesis program performs tasks generally associated with aircraft preliminary design and allows an analyst the capability of performing parametric studies in a rapid manner. GASP emphasizes small fixed-wing aircraft employing propulsion systems varying froma single piston engine with fixed pitch propeller through twin turboprop/ turbofan powered business or transport type aircraft. The program, which may be operated from a computer terminal in either the batch or interactive graphic mode, is comprised of modules representing the various technical disciplines integrated into a computational flow which ensures that the interacting effects of design variables are continuously accounted for in the aircraft sizing procedure. The model is a useful tool for comparing configurations, assessing aircraft performance and economics, performing tradeoff and sensitivity studies, and assessing the impact of advanced technologies on aircraft performance and economics.

  1. Investigation of non-reciprocal magnon propagation using lock-in thermography

    NASA Astrophysics Data System (ADS)

    Wid, Olga; Bauer, Jan; Müller, Alexander; Breitenstein, Otwin; Parkin, Stuart S. P.; Schmidt, Georg

    2017-04-01

    We have investigated the unidirectional spin wave heat conveyer effect in a 200 nm thin yttrium iron garnet (YIG) film using lock-in thermography (LIT). This originates from the non-reciprocal propagation of magnons, which leads to an asymmetric heat transport. To excite the spin waves we use two different respective antenna geometries: a coplanar waveguide (CPW) or a ‘microstrip’-like antenna on top of the YIG. By using the CPW and comparing the results for the Damon-Eshbach and the backward volume modes we are able to show that the origin of the asymmetric heat profile are indeed the non-reciprocal spin waves. Using the ‘microstrip’-like geometry we can confirm these results and we can even observe a distinct excitation profile along the antenna due to small field inhomogeneities.

  2. Probabilistic Modeling of Ceramic Matrix Composite Strength

    NASA Technical Reports Server (NTRS)

    Shan, Ashwin R.; Murthy, Pappu L. N.; Mital, Subodh K.; Bhatt, Ramakrishna T.

    1998-01-01

    Uncertainties associated with the primitive random variables such as manufacturing process (processing temperature, fiber volume ratio, void volume ratio), constituent properties (fiber, matrix and interface), and geometric parameters (ply thickness, interphase thickness) have been simulated to quantify the scatter in the first matrix cracking strength (FMCS) and the ultimate tensile strength of SCS-6/RBSN (SiC fiber (SCS-6) reinforced reaction-bonded silicon nitride composite) ceramic matrix composite laminate at room temperature. Cumulative probability distribution function for the FMCS and ultimate tensile strength at room temperature (RT) of (0)(sub 8), (0(sub 2)/90(sub 2), and (+/-45(sub 2))(sub S) laminates have been simulated and the sensitivity of primitive variables to the respective strengths have been quantified. Computationally predicted scatter of the strengths for a uniaxial laminate have been compared with those from limited experimental data. Also the experimental procedure used in the tests has been described briefly. Results show a very good agreement between the computational simulation and the experimental data. Dominating failure modes in (0)(sub 8), (0/90)(sub s) and (+/-45)(sub S) laminates have been identified. Results indicate that the first matrix cracking strength for the (0)(sub S), and (0/90)(sub S) laminates is sensitive to the thermal properties, modulus and strengths of both the fiber and matrix whereas the ultimate tensile strength is sensitive to the fiber strength and the fiber volume ratio. In the case of a (+/-45)(sub S), laminate, both the FMCS and the ultimate tensile strengths have a small scatter range and are sensitive to the fiber tensile strength as well as the fiber volume ratio.

  3. Classroom Ideas for Encouraging Thinking and Feeling: A Total Creativity Program for Individualizing and Humanizing the Learning Process. Volume Five.

    ERIC Educational Resources Information Center

    Williams, Frank E.

    This volume, the final one in the series, presents about 400 ideas which teachers can use to teach creative thinking. The ideas are classified according to teacher behavior (strategies or modes of teaching) and by types of pupil behavior, as described in the rationale for the cognitive-affective instructional (CAI) model presented in volume 2. The…

  4. Lamping process and application of ultra small U-shaped, whispery gallery mode (WGM) based optic fiber sensors

    NASA Astrophysics Data System (ADS)

    Chang, Yuan Cheng; Chiang, Chia Chin

    2015-07-01

    This study success to smaller and control the diameter of single mode optical fiber whispery gallery mode (WGM) to diameter 0.8 mm nonetching and nontaping treated. The sensitivity of this type ultra-small U-shape WGM strengthens neither etching nor taping fibre. The sensitivity we apply to thermo test depends on wavelength shift from 40 ~ 96°C (R2 = 0.99 ). The specially characteristics of the optical fiber could be tested for temperature, refraction, vibration, concussion, and CO2 detection.

  5. Behavioral Science Elementary Teacher Education Program. Final Report. Volume II.

    ERIC Educational Resources Information Center

    Michigan State Univ., East Lansing.

    Volume II separately details two model components: Scholarly Modes of Knowledge, in which problem-solving techniques and the applicability of subject content to teaching are emphasized, and Professional Use of Knowledge, in which the student translates what he knows about various disciplines and human learning into instructional strategies. Each…

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Raduha, S.; Butler, D.; Mozley, P. S.

    Here, we examined the potential impact on CO 2 transport of zones of deformation bands in reservoir rock that transition to opening-mode fractures within overlying caprock. Sedimentological and petrophysical measurements were collected along an approximately 5 m × 5 m outcrop of the Slick Rock and Earthy Members of the Entrada Sandstone on the eastern flank of the San Rafael Swell, Utah, USA. Measured deformation band permeability (2 mD) within the reservoir facies is about three orders of magnitude lower than the host sandstone. Average permeability of the caprock facies (0.0005 mD) is about seven orders of magnitude lower thanmore » the host sandstone. Aperture-based permeability estimates of the opening-mode caprock fractures are high (3.3 × 10 7 mD). High-resolution CO 2–H 2O transport models incorporate these permeability data at the millimeter scale. We then varied fault properties at the reservoir/caprock interface between open fractures and deformation bands as part of a sensitivity study. Numerical modeling results suggest that zones of deformation bands within the reservoir strongly compartmentalize reservoir pressures largely blocking lateral, cross-fault flow of supercritical CO 2. Significant vertical CO 2 transport into the caprock occurred in some scenarios along opening-mode fractures. The magnitude of this vertical CO 2 transport depends on the small-scale geometry of the contact between the opening-mode fracture and the zone of deformation bands, as well as the degree to which fractures penetrate caprock. Finally, the presence of relatively permeable units within the caprock allows storage of significant volumes of CO 2, particularly when the fracture network does not extend all the way through the caprock.« less

  7. Low-stress silicon nitride layers for MEMS applications

    NASA Astrophysics Data System (ADS)

    Iliescu, Ciprian; Wei, Jiashen; Chen, Bangtao; Ong, Poh Lam; Tay, Francis E. H.

    2006-12-01

    The paper presents two deposition methods for generation of SiN x layers with "zero" residual stress in PECVD reactors: mixed frequency and high power in high frequency mode (13.56 MHz). Traditionally, mix frequency mode is commonly used to produce low stress SiN x layers, which alternatively applies the HF and LF mode. However, due to the low deposition rate of LF mode, the combined deposition rate of mix frequency is quite small in order to produce homogenous SiN x layers. In the second method, a high power which was up to 600 W has been used, may also produce low residual stress (0-20 MPa), with higher deposition rate (250 to 350 nm/min). The higher power not only leads to higher dissociation rates of gases which results in higher deposition rates, but also brings higher N bonding in the SiN x films and higher compressive stress from higher volume expansion of SiN x films, which compensates the tensile stress and produces low residual stress. In addition, the paper investigates the influence of other important parameters which have great impact to the residual stress and deposition rates, such as reactant gases flow rate and pressure. By using the final optimized recipe, masking layer for anisotropic wet etching in KOH and silicon nitride cantilever have been successfully fabricated based on the low stress SiN x layers. Moreover, nanoporous membrane with 400nm pores has also been fabricated and tested for cell culture. By cultivating the mouse D1 mesenchymal stem cells on top of the nanoporous membrane, the results showed that mouse D1 mesenchymal stem cells were able to grow well. This shows that the nanoporous membrane can be used as the platform for interfacing with living cells to become biocapsules for biomolecular separation.

  8. Optimal ventilation of the anesthetized pediatric patient.

    PubMed

    Feldman, Jeffrey M

    2015-01-01

    Mechanical ventilation of the pediatric patient is challenging because small changes in delivered volume can be a significant fraction of the intended tidal volume. Anesthesia ventilators have traditionally been poorly suited to delivering small tidal volumes accurately, and pressure-controlled ventilation has become used commonly when caring for pediatric patients. Modern anesthesia ventilators are designed to deliver small volumes accurately to the patient's airway by compensating for the compliance of the breathing system and delivering tidal volume independent of fresh gas flow. These technology advances provide the opportunity to implement a lung-protective ventilation strategy in the operating room based upon control of tidal volume. This review will describe the capabilities of the modern anesthesia ventilator and the current understanding of lung-protective ventilation. An optimal approach to mechanical ventilation for the pediatric patient is described, emphasizing the importance of using bedside monitors to optimize the ventilation strategy for the individual patient.

  9. Endoclips vs large or small-volume epinephrine in peptic ulcer recurrent bleeding

    PubMed Central

    Ljubicic, Neven; Budimir, Ivan; Biscanin, Alen; Nikolic, Marko; Supanc, Vladimir; Hrabar, Davor; Pavic, Tajana

    2012-01-01

    AIM: To compare the recurrent bleeding after endoscopic injection of different epinephrine volumes with hemoclips in patients with bleeding peptic ulcer. METHODS: Between January 2005 and December 2009, 150 patients with gastric or duodenal bleeding ulcer with major stigmata of hemorrhage and nonbleeding visible vessel in an ulcer bed (Forrest IIa) were included in the study. Patients were randomized to receive a small-volume epinephrine group (15 to 25 mL injection group; Group 1, n = 50), a large-volume epinephrine group (30 to 40 mL injection group; Group 2, n = 50) and a hemoclip group (Group 3, n = 50). The rate of recurrent bleeding, as the primary outcome, was compared between the groups of patients included in the study. Secondary outcomes compared between the groups were primary hemostasis rate, permanent hemostasis, need for emergency surgery, 30 d mortality, bleeding-related deaths, length of hospital stay and transfusion requirements. RESULTS: Initial hemostasis was obtained in all patients. The rate of early recurrent bleeding was 30% (15/50) in the small-volume epinephrine group (Group 1) and 16% (8/50) in the large-volume epinephrine group (Group 2) (P = 0.09). The rate of recurrent bleeding was 4% (2/50) in the hemoclip group (Group 3); the difference was statistically significant with regard to patients treated with either small-volume or large-volume epinephrine solution (P = 0.0005 and P = 0.045, respectively). Duration of hospital stay was significantly shorter among patients treated with hemoclips than among patients treated with epinephrine whereas there were no differences in transfusion requirement or even 30 d mortality between the groups. CONCLUSION: Endoclip is superior to both small and large volume injection of epinephrine in the prevention of recurrent bleeding in patients with peptic ulcer. PMID:22611315

  10. Tripolar acytokinetic mitosis and formation of feto-maternal syncytia in the bovine placentome: different modes of the generation of multinuclear cells.

    PubMed

    Klisch, K; Pfarrer, C; Schuler, G; Hoffmann, B; Leiser, R

    1999-08-01

    The vast majority of trophoblast giant cells in the ruminant placenta are binuclear and are believed to derive from mononuclear trophoblastic cells by a single acytokinetic mitosis. There is no satisfactory explanation for the generation of the small proportion of trophoblast giant cells with one, three, or more nuclei. In this light-and electronmicroscopic study of bovine placentomal tissue from the second half of gestation, developmental stages of the trophoblast giant cells are investigated. Large mitotic figures indicate mitotic polyploidization, which is proposed to be due to two subsequent acytokinetic mitoses. Tripolar mitoses offer an explanation for the development of trinucleate trophoblast giant cells. Measurements of nuclear volumes in a series of semithin sections revealed that three size classes of trophoblast giant cells occur. The approximately doubling of nuclear volume between each class is thought to reflect different levels of DNA content that result from polyploidization in this cell type. Although trinuclear feto-maternal hybrid cells are the standard outcome of the fusion of binuclear trophoblast giant cells with uterine epithelial cells, some syncytia with at least five nuclei were observed in the uterine epithelium.

  11. Mode structure of planar optical antennas on dielectric substrates

    DOE PAGES

    Word, Robert C.; Konenkamp, Rolf

    2016-08-08

    Here, we report a numerical study, supported by photoemission electron microscopy (PEEM), of sub-micron planar optical antennas on transparent substrate. We find these antennas generate intricate near-field spatial field distributions with odd and even numbers of nodes. We show that the field distributions are primarily superpositions of planar surface plasmon polariton modes confined to the metal/substrate interface. The mode structure provides opportunities for coherent switching and optical control in sub-micron volumes.

  12. GEODYN operations description, volume 3. [computer program for estimation of orbit and geodetic parameters

    NASA Technical Reports Server (NTRS)

    Martin, T. V.; Mullins, N. E.

    1972-01-01

    The operating and set-up procedures for the multi-satellite, multi-arc GEODYN- Orbit Determination program are described. All system output is analyzed. The GEODYN Program is the nucleus of the entire GEODYN system. It is a definitive orbit and geodetic parameter estimation program capable of simultaneously processing observations from multiple arcs of multiple satellites. GEODYN has two modes of operation: (1) the data reduction mode and (2) the orbit generation mode.

  13. Pulsed Direct Current Electrospray: Enabling Systematic Analysis of Small Volume Sample by Boosting Sample Economy.

    PubMed

    Wei, Zhenwei; Xiong, Xingchuang; Guo, Chengan; Si, Xingyu; Zhao, Yaoyao; He, Muyi; Yang, Chengdui; Xu, Wei; Tang, Fei; Fang, Xiang; Zhang, Sichun; Zhang, Xinrong

    2015-11-17

    We had developed pulsed direct current electrospray ionization mass spectrometry (pulsed-dc-ESI-MS) for systematically profiling and determining components in small volume sample. Pulsed-dc-ESI utilized constant high voltage to induce the generation of single polarity pulsed electrospray remotely. This method had significantly boosted the sample economy, so as to obtain several minutes MS signal duration from merely picoliter volume sample. The elongated MS signal duration enable us to collect abundant MS(2) information on interested components in a small volume sample for systematical analysis. This method had been successfully applied for single cell metabolomics analysis. We had obtained 2-D profile of metabolites (including exact mass and MS(2) data) from single plant and mammalian cell, concerning 1034 components and 656 components for Allium cepa and HeLa cells, respectively. Further identification had found 162 compounds and 28 different modification groups of 141 saccharides in a single Allium cepa cell, indicating pulsed-dc-ESI a powerful tool for small volume sample systematical analysis.

  14. Preventing Raman Lasing in High-Q WGM Resonators

    NASA Technical Reports Server (NTRS)

    Savchenkov, Anatoliy; Matsko, Andrey; Strekalov, Dmitry; Maleki, Lute

    2007-01-01

    A generic design has been conceived to suppress the Raman effect in whispering- gallery-mode (WGM) optical resonators that have high values of the resonance quality factor (Q). Although it is possible to exploit the Raman effect (even striving to maximize the Raman gain to obtain Raman lasing), the present innovation is intended to satisfy a need that arises in applications in which the Raman effect inhibits the realization of the full potential of WGM resonators as frequency-selection components. Heretofore, in such applications, it has been necessary to operate high-Q WGM resonators at unattractively low power levels to prevent Raman lasing. (The Raman-lasing thresholds of WGM optical resonators are very low and are approximately proportional to Q(sup -2)). Heretofore, two ways of preventing Raman lasting at high power levels have been known, but both entail significant disadvantages: A resonator can be designed so that the optical field is spread over a relatively large mode volume to bring the power density below the threshold. For any given combination of Q and power level, there is certain mode volume wherein Raman lasing does not start. Unfortunately, a resonator that has a large mode volume also has a high spectral density, which is undesirable in a typical photonic application. A resonator can be cooled to the temperature of liquid helium, where the Raman spectrum is narrower and, therefore, the Raman gain is lower. However, liquid-helium cooling is inconvenient. The present design overcomes these disadvantages, making it possible to operate a low-spectral-density (even a single-mode) WGM resonator at a relatively high power level at room temperature, without risk of Raman lasing.

  15. Zero-mode waveguides

    DOEpatents

    Levene, Michael J.; Korlach, Jonas; Turner, Stephen W.; Craighead, Harold G.; Webb, Watt W.

    2007-02-20

    The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide.

  16. Management of the high-order mode content in large (40 microm) core photonic bandgap Bragg fiber laser.

    PubMed

    Gaponov, D A; Février, S; Devautour, M; Roy, P; Likhachev, M E; Aleshkina, S S; Salganskii, M Y; Yashkov, M V; Guryanov, A N

    2010-07-01

    Very large-mode-area Yb(3+)-doped single-mode photonic bandgap (PBG) Bragg fiber oscillators are considered. The transverse hole-burning effect is numerically modeled, which helps properly design the PBG cladding and the Yb(3+)-doped region for the high-order mode content to be carefully controlled. A ratio of the Yb(3+)-doped region diameter to the overall core diameter of 40% allows for single-mode emission, even for small spool diameters of 15 cm. Such a fiber was manufactured and subsequently used as the core element of a cw oscillator. Very good beam quality parameter M(2)=1.12 and slope efficiency of 80% were measured. Insensitivity to bending, exemplified by the absence of temporal drift of the beam, was demonstrated for curvature diameter as small as 15 cm.

  17. Small-area low-power heart condition monitoring system using dual-mode SAR-ADC for low-cost wearable healthcare systems.

    PubMed

    Shin, Young-San; Wee, Jae-Kyung; Song, Inchae; Lee, Seongsoo

    2015-01-01

    Heart rate monitoring is useful to detect many cardiovascular diseases. It can be implemented in a small device with low power consumption, and it can exploit low-cost piezoelectric pressure sensors to measure heart rate. However, it is also desirable to transmit heartbeat waveform for emergency treatment, which significantly increases transmission power. In this paper, a low-cost wireless heart condition monitoring SoC is proposed. It can monitor and transmit both heart rate and heartbeat waveform, but the hardware is extremely simplified to achieve in a small package. By slight modification of successive-approximation analog-digital converter, it can count heart rate and read out heartbeat waveform with the same hardware. In the normal mode, only an 8-bit heart rate is transmitted for power reduction. If the heart rate is out of a given range, it goes to the emergency mode and a 10-bit heartbeat waveform is transmitted for fast treatment. The fabricated chip size is 1.1 mm2 in 0.11 μ m CMOS technology, including the radio-frequency transmitter. The measured power consumption is 161.8 μ W in normal mode and 507.3 μ W in emergency mode, respectively. The proposed SoC achieves low-cost, small area, and low-power. It is useful as part of a disposable healthcare system.

  18. Small Business Management Volume III: Curriculum. An Adult Education Program.

    ERIC Educational Resources Information Center

    Persons, Edgar A.; Swanson, Gordon I.

    The small business management adult education program outlined in this curriculum guide is designed to help small business entrepreneurs solve their business management problems and attain the goals they have established for their businesses and their families. (An instructor's manual and practice problems are in separate volumes.) The 3-year…

  19. 40 CFR 80.250 - How is the small refiner sulfur baseline and volume determined?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 17 2012-07-01 2012-07-01 false How is the small refiner sulfur... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Hardship Provisions § 80.250 How is the small refiner sulfur baseline and volume determined? (a)(1) The...

  20. 40 CFR 80.250 - How is the small refiner sulfur baseline and volume determined?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 16 2011-07-01 2011-07-01 false How is the small refiner sulfur... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Hardship Provisions § 80.250 How is the small refiner sulfur baseline and volume determined? (a)(1) The...

  1. 40 CFR 80.250 - How is the small refiner sulfur baseline and volume determined?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 17 2014-07-01 2014-07-01 false How is the small refiner sulfur... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Hardship Provisions § 80.250 How is the small refiner sulfur baseline and volume determined? (a)(1) The...

  2. 40 CFR 80.250 - How is the small refiner sulfur baseline and volume determined?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false How is the small refiner sulfur... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Hardship Provisions § 80.250 How is the small refiner sulfur baseline and volume determined? (a)(1) The...

  3. 40 CFR 80.250 - How is the small refiner sulfur baseline and volume determined?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false How is the small refiner sulfur... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Hardship Provisions § 80.250 How is the small refiner sulfur baseline and volume determined? (a)(1) The...

  4. Spherical and cylindrical particle resonator as a cloak system

    NASA Astrophysics Data System (ADS)

    Minin, I. V.; Minin, O. V.; Eremeev, A. I.; Tseplyaev, I. S.

    2018-05-01

    The concept of dielectric spherical or cylindrical particle in resonant mode as a cloak system is offered. In fundamental modes (modes with the smallest volume correspond to |m| = l, and s = 1) the field is concentrated mostly in the equatorial plane and at the surface of the sphere. Thus under resonance modes, such perturbation due to cuboid particle inserted in the spherical or cylindrical particle has almost no effect on the field forming resonance regardless of the value of internal particle material (defect) as long as this material does not cover the region where resonance takes place.

  5. Single phase bi-directional AC-DC converter with reduced passive components size and common mode electro-magnetic interference

    DOEpatents

    Mi, Chris; Li, Siqi

    2017-01-31

    A bidirectional AC-DC converter is presented with reduced passive component size and common mode electro-magnetic interference. The converter includes an improved input stage formed by two coupled differential inductors, two coupled common and differential inductors, one differential capacitor and two common mode capacitors. With this input structure, the volume, weight and cost of the input stage can be reduced greatly. Additionally, the input current ripple and common mode electro-magnetic interference can be greatly attenuated, so lower switching frequency can be adopted to achieve higher efficiency.

  6. Gravitational waves and cosmic strings

    NASA Astrophysics Data System (ADS)

    Siemens, Xavier

    2002-08-01

    Cosmic strings are potential candidates for a variety of interesting cosmological phenomena such as gamma ray bursts, gravitational wave bursts and ultra high energy cosmic rays. The predictions of cosmic string models, however, depend sensitively on the so far unresolved question of the size of the small-scale structure. This thesis deals largely with this problem. First, I present a gravitational back-reaction model that assumes the interaction between all Fourier modes that make up a given perturbation on a long cosmic string. This calculation leads to the generally accepted value of the small scale structure cutoff. It also, however, leads to paradoxical behaviour when applied to two oppositely moving modes: As one of the modes is stretched conformally the gravitational power radiated approaches a constant. This result is in contradiction with our expectation for the straight string limit in which no power is radiated. A more careful investigation of this problem reveals that, in the case of two oppositely moving modes, the gravitational power is exponentially suppressed when the wavelengths of the modes are sufficiently different. I use this result to construct an improved gravitational back-reaction model in which modes of very different wavelengths do not interact. This model leads to a new small scale structure cutoff which is sensitive to the initial spectrum of perturbations present on the string. I also tentatively examine the consequences of this result for the evolution of cosmic string loops. Finally, I investigate the effect of the presence of small scale structure on the gravitational wave-bursts produced at cosmic string cusps.

  7. Rapid Cycle Amine (RCA) 3.0 System Development

    NASA Technical Reports Server (NTRS)

    Chullen, Cinda; Campbell, Colin; Papale, William; Hawes, Kevin; Wichowski, Robert

    2015-01-01

    The Rapid Cycle Amine (RCA) 3.0 system is currently under development by NASA, the Lyndon B. Johnson Space Center (JSC) in conjunction with United Technologies Corporation Aerospace Systems (UTAS). The RCA technology is a new carbon dioxide (CO2) and humidity removal system that has been baselined for the Advanced Extravehicular Mobility Unit (AEMU) Portable Life Support System. The evolution of the RCA development has progressed through several iterations of technology readiness levels including RCA 1.0, RCA 2.0, and RCA 3.0 test articles. The RCA is an advancement over currently technologies due to its unique regeneration capability. The RCA is capable of simultaneously removing CO2 and humidity from an influent air steam and subsequent regeneration when exposed to a vacuum source. The RCA technology uses two solid amine sorbent beds in an alternating fashion to adsorb CO2 and water (uptake mode) and desorb CO2 and water (regeneration mode) at the same time. The two beds operate in an efficient manner so that while one bed is in the uptake mode, the other is in the regeneration mode, thus continuously providing an on-service sorbent bed by which CO2 and humidity may be removed. The RCA 2.0 and 3.0 test articles were designed with a novel valve assembly which allows for switching between uptake and regeneration modes with only one moving part while minimizing gas volume losses to the vacuum source by means of an internal pressure equalization step during actuation. The RCA technology also is low power, small, and has performed extremely well in all development testing thus far. A final design was selected for the RCA 3.0, fabricated, assembled, and performance tested in 2014 with delivery to NASAJSC in January 2015. This paper will provide an overview on the RCA 3.0 system design and results of pre-delivery testing with references to the development of RCA 1.0 and RCA 2.0.

  8. Radially localized helicon modes in nonuniform plasma

    PubMed

    Breizman; Arefiev

    2000-04-24

    A radial density gradient in an axisymmetric cylindrical plasma column forms a potential well for nonaxisymmetric helicon modes ( m not equal0). This paper presents an analytic description of such modes in the limit of small longitudinal wave numbers. The corresponding mode equation indicates the possibility of efficient resonant absorption of rf power in helicon discharges at unusually low frequencies.

  9. Infrared astronomical satellite (IRAS) catalogs and atlases. Volume 7: The small scale structure catalog

    NASA Technical Reports Server (NTRS)

    Helou, George (Editor); Walker, D. W. (Editor)

    1988-01-01

    The Infrared Astronomical Satellite (IRAS) was launched January 26, 1983. During its 300-day mission, it surveyed over 96 pct of the celestial sphere at four infrared wavelengths, centered approximately at 12, 25, 60, and 100 microns. Volume 1 describes the instrument, the mission, and the data reduction process. Volumes 2 through 6 present the observations of the approximately 245,000 individual point sources detected by IRAS; each volume gives sources within a specified range of declination. Volume 7 gives the observations of the approximately 16,000 sources spatially resolved by IRAS and smaller than 8'. This is Volume 7, The Small Scale Structure Catalog.

  10. Advanced positive airway pressure modes: adaptive servo ventilation and volume assured pressure support.

    PubMed

    Selim, Bernardo; Ramar, Kannan

    2016-09-01

    Volume assured pressure support (VAPS) and adaptive servo ventilation (ASV) are non-invasive positive airway pressure (PAP) modes with sophisticated negative feedback control systems (servomechanism), having the capability to self-adjust in real time its respiratory controlled variables to patient's respiratory fluctuations. However, the widespread use of VAPS and ASV is limited by scant clinical experience, high costs, and the incomplete understanding of propriety algorithmic differences in devices' response to patient's respiratory changes. Hence, we will review and highlight similarities and differences in technical aspects, control algorithms, and settings of each mode, focusing on the literature search published in this area. One hundred twenty relevant articles were identified by Scopus, PubMed, and Embase databases from January 2010 to 2016, using a combination of MeSH terms and keywords. Articles were further supplemented by pearling. Recommendations were based on the literature review and the authors' expertise in this area. Expert commentary: ASV and VAPS differ in their respiratory targets and response to a respiratory fluctuation. The VAPS mode targets a more consistent minute ventilation, being recommended in the treatment of sleep related hypoventilation disorders, while ASV mode attempts to provide a more steady breathing airflow pattern, treating successfully most central sleep apnea syndromes.

  11. Free vibration of multiwall carbon nanotubes

    NASA Astrophysics Data System (ADS)

    Wang, C. Y.; Ru, C. Q.; Mioduchowski, A.

    2005-06-01

    A multiple-elastic shell model is applied to systematically study free vibration of multiwall carbon nanotubes (MWNTs). Using Flugge [Stresses in Shells (Springer, Berlin, 1960)] equations of elastic shells, vibrational frequencies and associated modes are calculated for MWNTs of innermost radii 5 and 0.65 nm, respectively. The emphasis is placed on the effect of interlayer van der Waals (vdW) interaction on free vibration of MWNTs. Our results show that the interlayer vdW interaction has a crucial effect on radial (R) modes of large-radius MWNTs (e.g., of the innermost radius 5 nm), but is less pronounced for R modes of small-radius MWNTs (e.g., of the innermost radius 0.65 nm), and usually negligible for torsional (T) and longitudinal (L) modes of MWNTs. This is attributed to the fact that the interlayer vdW interaction, characterized by a radius-independent vdW interaction coefficient, depends on radial deflections only, and is dominant only for large-radius MWNTs of lower radial rigidity but less pronounced for small-radius MWNTs of much higher radial rigidity. As a result, the R modes of large-radius MWNTs are typically collective motions of almost all nested tubes, and the R modes of small-radius MWNTs, as well as the T and L modes of MWNTs, are basically vibrations of individual tubes. In particular, an approximate single-shell model is suggested to replace the multiple-shell model in calculating the lowest frequency of R mode of thin MWNTs (defined by the innermost radius-to-thickness ratio not less than 4) with relative errors less than 10%. In addition, the simplified Flugge single equation is adopted to substitute the exact Flugge equations in determining the R-mode frequencies of MWNTs with relative errors less than 10%.

  12. Development of a small single-ring OpenPET prototype with a novel transformable architecture.

    PubMed

    Tashima, Hideaki; Yoshida, Eiji; Inadama, Naoko; Nishikido, Fumihiko; Nakajima, Yasunori; Wakizaka, Hidekatsu; Shinaji, Tetsuya; Nitta, Munetaka; Kinouchi, Shoko; Suga, Mikio; Haneishi, Hideaki; Inaniwa, Taku; Yamaya, Taiga

    2016-02-21

    The single-ring OpenPET (SROP), for which the detector arrangement has a cylinder shape cut by two parallel planes at a slant angle to form an open space, is our original proposal for in-beam PET. In this study, we developed a small prototype of an axial-shift type SROP (AS-SROP) with a novel transformable architecture for a proof-of-concept. In the AS-SROP, detectors originally forming a cylindrical PET are axially shifted little by little. We designed the small AS-SROP prototype for 4-layer depth-of-interaction detectors arranged in a ring diameter of 250 mm. The prototype had two modes: open and closed. The open mode formed the SROP with the open space of 139 mm and the closed mode formed a conventional cylindrical PET. The detectors were simultaneously moved by a rotation handle allowing them to be transformed between the two modes. We evaluated the basic performance of the developed prototype and carried out in-beam imaging tests in the HIMAC using (11)C radioactive beam irradiation. As a result, we found the open mode enabled in-beam PET imaging at a slight cost of imaging performance; the spatial resolution and sensitivity were 2.6 mm and 5.1% for the open mode and 2.1 mm and 7.3% for the closed mode. We concluded that the AS-SROP can minimize the decrease of resolution and sensitivity, for example, by transforming into the closed mode immediately after the irradiation while maintaining the open space only for the in-beam PET measurement.

  13. Mobile visual communications and displays

    NASA Astrophysics Data System (ADS)

    Valliath, George T.

    2004-09-01

    The different types of mobile visual communication modes and the types of displays needed in cellular handsets are explored. The well-known 2-way video conferencing is only one of the possible modes. Some modes are already supported on current handsets while others need the arrival of advanced network capabilities to be supported. Displays for devices that support these visual communication modes need to deliver the required visual experience. Over the last 20 years the display has grown in size while the rest of the handset has shrunk. However, the display is still not large enough - the processor performance and network capabilities continue to outstrip the display ability. This makes the display a bottleneck. This paper will explore potential solutions to a small large image on a small handset.

  14. Protective mechanical ventilation in United Kingdom critical care units: A multicentre audit

    PubMed Central

    Martin, Matthew J; Richardson, Neil; Bourdeaux, Christopher P

    2016-01-01

    Lung protective ventilation is becoming increasingly used for all critically ill patients being mechanically ventilated on a mandatory ventilator mode. Compliance with the universal application of this ventilation strategy in intensive care units in the United Kingdom is unknown. This 24-h audit of ventilation practice took place in 16 intensive care units in two regions of the United Kingdom. The mean tidal volume for all patients being ventilated on a mandatory ventilator mode was 7.2(±1.4) ml kg−1 predicted body weight and overall compliance with low tidal volume ventilation (≤6.5 ml kg−1 predicted body weight) was 34%. The mean tidal volume for patients ventilated with volume-controlled ventilation was 7.0(±1.2) ml kg−1 predicted body weight and 7.9(±1.8) ml kg−1 predicted body weight for pressure-controlled ventilation (P < 0.0001). Overall compliance with recommended levels of positive end-expiratory pressure was 72%. Significant variation in practice existed both at a regional and individual unit level. PMID:28979556

  15. Protective mechanical ventilation in United Kingdom critical care units: A multicentre audit.

    PubMed

    Newell, Christopher P; Martin, Matthew J; Richardson, Neil; Bourdeaux, Christopher P

    2017-05-01

    Lung protective ventilation is becoming increasingly used for all critically ill patients being mechanically ventilated on a mandatory ventilator mode. Compliance with the universal application of this ventilation strategy in intensive care units in the United Kingdom is unknown. This 24-h audit of ventilation practice took place in 16 intensive care units in two regions of the United Kingdom. The mean tidal volume for all patients being ventilated on a mandatory ventilator mode was 7.2(±1.4) ml kg -1 predicted body weight and overall compliance with low tidal volume ventilation (≤6.5 ml kg -1 predicted body weight) was 34%. The mean tidal volume for patients ventilated with volume-controlled ventilation was 7.0(±1.2) ml kg -1 predicted body weight and 7.9(±1.8) ml kg -1 predicted body weight for pressure-controlled ventilation ( P  < 0.0001). Overall compliance with recommended levels of positive end-expiratory pressure was 72%. Significant variation in practice existed both at a regional and individual unit level.

  16. Archimedes Revisited: A Faster, Better, Cheaper Method of Accurately Measuring the Volume of Small Objects

    ERIC Educational Resources Information Center

    Hughes, Stephen W.

    2005-01-01

    A little-known method of measuring the volume of small objects based on Archimedes' principle is described, which involves suspending an object in a water-filled container placed on electronic scales. The suspension technique is a variation on the hydrostatic weighing technique used for measuring volume. The suspension method was compared with two…

  17. Raman bands in Ag nanoparticles obtained in extract of Opuntia ficus-indica plant

    NASA Astrophysics Data System (ADS)

    Bocarando-Chacon, J.-G.; Cortez-Valadez, M.; Vargas-Vazquez, D.; Rodríguez Melgarejo, F.; Flores-Acosta, M.; Mani-Gonzalez, P. G.; Leon-Sarabia, E.; Navarro-Badilla, A.; Ramírez-Bon, R.

    2014-05-01

    Silver nanoparticles have been obtained in an extract of Opuntia ficus-indica plant. The size and distribution of nanoparticles were quantified by atomic force microscopy (AFM). The diameter was estimated to be about 15 nm. In addition, energy dispersive X-ray spectroscopy (EDX) peaks of silver were observed in these samples. Three Raman bands have been experimentally detected at 83, 110 and 160 cm-1. The bands at 83 and 110 cm-1 are assigned to the silver-silver Raman modes (skeletal modes) and the Raman mode located at 160 cm-1 has been assigned to breathing modes. Vibrational assignments of Raman modes have been carried out based on the Density Functional Theory (DFT) quantum mechanical calculation. Structural and vibrational properties for small Agn clusters with 2≤n≤9 were determined. Calculated Raman modes for small metal clusters have an approximation trend of Raman bands. These Raman bands were obtained experimentally for silver nanoparticles (AgNP).

  18. Antarctic icebergs distributions 1992-2014

    NASA Astrophysics Data System (ADS)

    Tournadre, J.; Bouhier, N.; Girard-Ardhuin, F.; Rémy, F.

    2016-01-01

    Basal melting of floating ice shelves and iceberg calving constitute the two almost equal paths of freshwater flux between the Antarctic ice cap and the Southern Ocean. The largest icebergs (>100 km2) transport most of the ice volume but their basal melting is small compared to their breaking into smaller icebergs that constitute thus the major vector of freshwater. The archives of nine altimeters have been processed to create a database of small icebergs (<8 km2) within open water containing the positions, sizes, and volumes spanning the 1992-2014 period. The intercalibrated monthly ice volumes from the different altimeters have been merged in a homogeneous 23 year climatology. The iceberg size distribution, covering the 0.1-10,000 km2 range, estimated by combining small and large icebergs size measurements follows well a power law of slope -1.52 ± 0.32 close to the -3/2 laws observed and modeled for brittle fragmentation. The global volume of ice and its distribution between the ocean basins present a very strong interannual variability only partially explained by the number of large icebergs. Indeed, vast zones of the Southern Ocean free of large icebergs are largely populated by small iceberg drifting over thousands of kilometers. The correlation between the global small and large icebergs volumes shows that small icebergs are mainly generated by large ones breaking. Drifting and trapping by sea ice can transport small icebergs for long period and distances. Small icebergs act as an ice diffuse process along large icebergs trajectories while sea ice trapping acts as a buffer delaying melting.

  19. Efficiency of using direct-flow burners and nozzles in implementation of dry-bottom ash removal at the TPP-210A boiler furnace

    NASA Astrophysics Data System (ADS)

    Arkhipov, A. M.; Kanunnikov, A. A.; Kirichkov, V. S.; Prokhorov, V. B.; Fomenko, M. V.; Chernov, S. L.

    2017-02-01

    In reconstruction of operating pulverized coal-fired boilers, one of the main factors is the choice of a method for slag removal: dry bottom ash removal (DBAR) or slag-tap removal (STR). In this case, ecological and economic aspects should be taken into account, and also the early ignition of pulverized coal fuel, the reliability of operation of the furnace walls in the mode without slagging, and the stability of slag removal should be provided. In this work, issues of changeover of the pulverized coal-fired boilers of the TPP-210A type from the STR mode to the DBAR mode are considered. As of today, the main problems during the operation of these boilers are the high emissions of nitrogen oxides together with flue gases into the atmosphere and the appropriated payoffs, a small range of loads available, the necessity of stabilization of the pulverizedcoal flame sustainability by using the highly reactive fuel, large mechanical fuel underburning, etc. Results of studying aerodynamics of a furnace with DBAR obtained in the process of physical simulation are given; technical solutions and preliminary design (configuration of burners and nozzles in the boiler furnace, conceptual design of the pulverized coal burner, configuration of TPP-210A boiler with the low heat liberation of furnace cross-section and volumetric heat release) are set forth, which are associated with the optimization of aerodynamics of furnace volume, when the direct-flow burners and nozzles are used, and with organization of the efficient staged combustion of solid fuel. Two versions of possible modernization of a boiler unit are considered. Under conditions of the planned increase in the steam production capacity, the most promising measures are as follows: the DBAR implementation with reducing heat releases of the cross-section and volume of the furnace approximately by half, the installation of the direct-flow burners and nozzles with injection of recirculation gases into the active combustion zone by bleeding them from the turning chamber.

  20. Spin-dependent excitation of plasma modes in non-neutral ion plasmas

    NASA Astrophysics Data System (ADS)

    Sawyer, Brian C.; Britton, Joe W.; Bollinger, John J.

    2011-10-01

    We report on a new technique for exciting and sensitively detecting plasma modes in small, cold non-neutral ion plasmas. The technique uses an optical dipole force generated from laser beams to excite plasma modes. By making the force spin- dependent (i.e. depend on the internal state of the atomic ion) very small mode excitations (<100 nm) can be detected through spin-motion entanglement. Even when the optical dipole force is homogeneous throughout the plasma, short wavelength modes on the order of the interparticle spacing can in principle be excited and detected through the spin dependence of the force. We use this technique to study the drumhead modes of single plane triangular arrays of a few hundred Be+ ions. Spin-dependent mode excitation is interesting in this system because it provides a means of engineering an Ising interaction on a 2-D triangular lattice. For the case of an anti-ferromagnetic interaction, this system exhibits spin frustration on a scale that is at present computationally intractable. Work supported by the DARPA OLE program and NIST.

  1. Experimental evidence for millisecond activation timescales using the Fast IN Chamber (FINCH) measurements

    NASA Astrophysics Data System (ADS)

    Bundke, U.; Jaenicke, R.; Klein, H.; Nillius, B.; Reimann, B.; Wetter, T.; Bingemer, H.

    2009-04-01

    Ice formation in clouds is a subject of great practical and fundamental importance since the occurrence of ice particle initializes dramatic changes in the microphysical structure of the cloud, which finally ends in the formation of precipitation. The initially step of ice formation is largely unknown. Homogenous nucleation of ice occurs only below -40 °C. If an ice nucleus (IN) is present, heterogeneous nucleation may occur at higher temperature. Here deposition freezing, condensation and immersion freezing as well as contact freezing are known. Also growth rates of ice particles are known as function of crystal surface properties, temperature and super saturation. Timescales for homogenous freezing activation in the order of 0.01 seconds and nucleation rates have been measured by Anderson et al. (1980) and Hagen et al., (1981) using their expansion cloud chamber. This contribution of deposition mode freezing measurements by the ice nucleus counter FINCH presents evidence that the activation timescale of this freezing mode is in the order of 1E-3 seconds. FINCH is an Ice Nucleus counter which activates IN in a supersaturated environment at freezing temperatures. The activation conditions are actively controlled by mixing three gas flows (aerosol, particle-free cold-dry and warm-humid flows).See Bundke et al. 2008 for details. In a special operation mode of FINCH we are able to produce a controlled peak super saturation in the order of 1 ms duration. For several test aerosols the results observed in this particular mode are comparable to normal mode operations, where the maximum super saturation remains for more than a second, thus leading to the conclusion that the time for activation is in the order of 1ms or less. References: R.J. Anderson et al, "A Study of Homogeneous Condensation Freezing Nucleation of Small Water Droplets in an Expansion Cloud Chamber, Journal of the Atmospheric Sciences, Vol. 37, 2508-2520, 1980 U.Bundke et al., "The fast Ice Nucleus chamber FINCH", Atmospheric Research, Volume 90, Issues 2-4, 180-186, DOI:10.1016/j.atmosres.2008.02.008, 2008 D.E. Hagen et al., "Homogenous Condensation Freezing Nucleation Rate Measurements for Small Water Droplets in an Expansion Cloud Chamber", Journal of the Atmospheric Sciences, Vol 38, 1236-1243, 1981 Acknowledgments: This work was supported by the German Research Foundation: SFB 641 "Tropospheric Ice Phase" TP A1, SPP1294 BU1432/3-1, JA344/12-1, by the Helmholtz Association: VI-233 "Aerosol Cloud Interactions" and by and by the EU FP6 Infastructure Project EUSAAR.

  2. 40 CFR 86.1838-01 - Small volume manufacturer certification procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... paragraph (c)(2). (i) Small volume in-use verification test vehicles may be procured from customers or may... miles, a manufacturer may demonstrate to the satisfaction of the Agency that, based on owner survey data...

  3. A Modified LC/MS/MS Method with Enhanced Sensitivity for the Determination of Scopolamine in Human Plasma

    NASA Technical Reports Server (NTRS)

    Wang, Zuwei; Vaksman, Zalman; Putcha, Lakshmi

    2008-01-01

    Intranasal scopolamine is a choice drug for the treatment of motion sickness during space flight because of its quick onset of action, short half-life and favorable sideeffects profile. The dose administered usually ranges between 0.1 and 0.4 mg. Such small doses make it difficult to detect concentrations of scopolamine in biological fluids using existing sensitive LC/MS/MS method, especially when the biological sample volumes are limited. To measure scopolamine in human plasma to facilitate pharmacokinetic evaluation of the drug, we developed a sensitive LC/MS/MS method using 96 well micro elution plates for solid phase extraction (SPE) of scopolamine in human plasma. Human plasma (100-250 micro L) were loaded onto Waters Oasis HLB 96 well micro elution plate and eluted with 50 L of organic solvent without evaporation and reconstitution. HPLC separation of the eluted sample was performed using an Agilent Zorbax SB-CN column (50 x 2.1 mm) at a flow rate of 0.2 mL/min for 3 minutes. The mobile phase for separation was 80:20 (v/v) methanol: ammonium acetate (30 mM) in water. Concentrations of scopolamine were determined using a Micromass Quattro Micro(TM) mass spectrometer with electrospray ionization (ESI). ESI mass spectra were acquired in positive ion mode with multiple reaction monitoring for the determination of scopolamine m/z = 304.2 right arrow 138.1 and internal standard hyoscyamine m/z = 290.2 right arrow 124.1. The method is rapid, reproducible, specific and has the following parameters: scopolamine and the IS are eluted at about 1.1 and 1.7 min respectively. The linear range is 25-10000 pg/mL for scopolamine in human plasma with correlation coefficients greater than 0.99 and CV less than 0.5%. The intra-day and inter-day CVs are less than 15% for quality control samples with concentrations of 75,300, and 750 pg/mL of scopolamine in human plasma. SPE using 96 well micro elution plates allows rapid sample preparation and enhanced sensitivity for the LC/MS/MS determination of scopolamine in a small volume of biological samples. The new method is also cost effective since it uses a small volume of organic solvents compared to the methods using SPE cartridges or regular 96 well SPE plates. This method can be successfully used for bioavailability and pharmacokinetic evaluations of scopolamine, especially when volumes of biological samples are limited. Further investigation to use automated SPE system with 96 well micro elution plates is planned.

  4. Carbon and oxygen isotope ratios of ecosystem respiration along an Oregon conifer transect: preliminary observations based on small-flask sampling.

    PubMed

    Ehleringer, J. R.; Cook, C. S.

    1998-01-01

    Isotope ratio analyses of atmospheric CO(2) at natural abundance have significant potential for contributing to our understanding of photosynthetic and respiration processes in forest ecosystems. Recent advances in isotope ratio mass spectrometry allow for rapid, on-line analysis of small volumes of CO(2) in air, and open new research opportunities at the ecophysiological, whole-organism, and atmospheric levels. Among the immediate applications are the carbon and oxygen isotope ratio analyses of carbon dioxide in atmospheric air. Routine analysis of carbon dioxide in air volumes of approximately 50-300 &mgr;l is accomplished by linking a commercially available, trace gas condenser and gas chromatograph to an isotope ratio mass spectrometer operated in continuous-flow mode. Samples collected in the field are stored in either gas-tight syringes or 100-ml flasks. The small sample volume required makes it possible to subsample the air in flasks for CO(2) and then to sample the remaining air volume for the analysis of the isotopic composition of either methane or nitrous oxide. Reliable delta(13)C and delta(18)O values can be obtained from samples collected and stored for 1-3 days. Longer-term storage, on the order of weeks, is possible for delta(13)C measurements without drift in the isotope ratio signal, and should also be possible for delta(18)O measurements. When linked with an infrared gas analyzer, pump and flask sampling system, it is feasible to sample CO(2) extensively in remote forest locations. The air-sampling system was used to measure the isotope ratios of atmospheric CO(2) and to conduct a regression analysis of the relationship between these two parameters. From the regression, we calculated the delta(13)C of ecosystem respiration of four coniferous ecosystems along a precipitation gradient in central Oregon. The ecosystems along the coast-to-interior Oregon (OTTER) gradient are dominated by spruce-hemlock forests at the wet, coastal sites (> 200 cm precipitation annually) to juniper woodlands (20 cm precipitation) at the interior, dry end of the transect. The delta(13)C values of ecosystem respiration along this transect differed by only 1.3 per thousand (range of -25.2 to -23.9 per thousand ) during August at the peak of the summer drought. Following autumn rains in September, the delta(13)C of ecosystem respiration in the four stands decreased; overall the difference in the carbon isotope ratio of ecosystem respiration among sites increased to 3.9 per thousand (-26.8 to -22.9 per thousand ).

  5. Use of Simpson's method of disc to detect early echocardiographic changes in Doberman Pinschers with dilated cardiomyopathy.

    PubMed

    Wess, G; Mäurer, J; Simak, J; Hartmann, K

    2010-01-01

    M-mode is the echocardiographic gold standard to diagnose dilated cardiomyopathy (DCM) in dogs, whereas Simpson's method of discs (SMOD) is the preferred method to detect echocardiographic evidence of disease in humans. To establish reference values for SMOD and to compare those with M-mode measurements. Nine hundred and sixty-nine examinations of 471 Doberman Pinschers. Using a prospective longitudinal study design. Reference values for SMOD were established using 75 healthy Doberman Pinschers >8 years old with <50 ventricular premature contractions (VPCs) in 24 hours. The ability of the new SMOD cut-off values, normalized to body surface area (BSA), for left ventricular end-diastolic volume (LVEDV/BSA >95mL/m(2) ) and end-systolic volume (LVESV/BSA > 55mL/m(2) ) to detect echocardiographic changes in Doberman Pinschers with DCM was compared with currently recommended M-mode values. Dogs with elevated SMOD values but normal M-mode measurements were followed-up using a prospective longitudinal study design. At the final examination 175 dogs were diagnosed with DCM according to both methods (M-mode and SMOD). At previous examinations, M-mode values were abnormal in 142 examinations only, whereas all 175 SMOD already had detected changes. Additionally, 19 of 154 dogs with >100 VPCs/24 hours and normal M-mode values had abnormal SMOD measurement. Six dogs with increased SMOD measurements remained healthy at several follow-up examinations (classified as false positive); in 24 dogs with increased SMOD measurements, no follow-up examinations were available (classified as unclear). SMOD measurements are superior to M-mode to detect early echocardiographic changes in Dobermans with occult DCM. Copyright © 2010 by the American College of Veterinary Internal Medicine.

  6. Evaluation of Bone Healing After Osteotomies Prepared With Er:YAG Laser in Contact and Noncontact Modes and Piezosurgery--An Animal Study.

    PubMed

    Gabrić, Dragana; Blašković, Marko; Gjorgijevska, Elizabeta; Mladenov, Mitko; Tašič, Blaž; Jurič, Ivona Bago; Ban, Ticijana

    2016-01-01

    To analyze the healing of bone tissue treated with Er:YAG laser contact and noncontact modes of and piezosurgery in a rat model using triangular laser profilometry. Twenty-four 10-week-old adult male Wistar rats were used in the study. Three osteotomies on the medial part of tibia were performed in each animal, 1 in the right tibia and 2 in the left tibia. The osteotomies were performed with a piezoelectric device set at maximal power and the Er:YAG laser in contact mode (power, 7.5 W; pulse energy, 375 mJ; repetition rate, 20 Hz; MSP mode) and noncontact mode (power, 7.5 W; pulse energy, 750 mJ; repetition rate, 10 Hz; QSP mode) with a novel type of circular, digitally controlled handpiece (x-Runner). After surgery, 6 animals were immediately euthanized (group 1), and the others were euthanized after 1 week (group 2, n = 6), 2 weeks (group 3, n = 6), and 3 weeks (group 4, n = 6). Bone healing after osteotomy was analyzed using a 3-dimensional laser scanning technique (ie, laser triangulation profilometry). The volume reduction rates are similar for all 3 techniques (0.2 to 0.25 mm(3) per week). Greater volume reduction of 0.25 mm3 per week was observed for the Er:YAG laser in noncontact mode (x-Runner). After 3 weeks, almost complete healing of the prepared osteotomy was observed. Within the limitations of this study, the osteotomies performed by the Er:YAG laser in digitally controlled noncontact mode healed the fastest. Copyright © 2016 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  7. Independent Orbiter Assessment (IOA): Assessment of the reaction control system, volume 5

    NASA Technical Reports Server (NTRS)

    Prust, Chet D.; Hartman, Dan W.

    1988-01-01

    The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed an analysis of the aft and forward Reaction Control System (RCS) hardware and Electrical Power Distribution and Control (EPD and C), generating draft failure modes and potential critical items. The IOA results were then compared to the proposed Post 51-L NASA FMEA/CIL baseline. This report documents the results of that comparison for the Orbiter RCS hardware and EPD and C systems. Volume 5 contains detailed analysis and superseded analysis worksheets and the NASA FMEA to IOA worksheet cross reference and recommendations.

  8. Independent Orbiter Assessment (IOA): Assessment of the communication and tracking subsystem, volume 3

    NASA Technical Reports Server (NTRS)

    Long, W. C.

    1988-01-01

    The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed and analysis of the Communication and Tracking hardware, generating draft failure modes and potential critical items. The IOA results were then compared to the NASA FMEA/CIL baseline. A resolution of each discrepancy from the comparison is provided through additional analysis as required. This report documents the results of that comparison for the Orbiter Communication and Tracking hardware. Volume 3 continues the presentation of IOA worksheets and contains the potential critical items list, detailed analysis, and the NASA FMEA to IOA worksheet cross reference and recommendations.

  9. Note: Comparative experimental studies on the performance of 2-2 piezocomposite for medical ultrasound transducers

    NASA Astrophysics Data System (ADS)

    Marinozzi, F.; Bini, F.; Biagioni, A.; Grandoni, A.; Spicci, L.

    2013-09-01

    The paper reports the experimental investigation of the behavior of 2-2 Lead Zirconate Titanate (PZT)-polymer composite transducers array for clinical ultrasound equipments. Several 2-2 plate composites having the same dicing pitch of 0.11 mm and different volume fractions were manufactured and investigated. Measurements were performed through different techniques such as electrical impedance, pulse-echo, and Laser Doppler Vibrometer. With the last one, maps of the surface displacement were presented relative to thickness mode and first lateral mode resonance frequencies. The transducers with volume fractions of the 40% resulted markedly inefficient, whereas the largest bandwidth and best band shape were achieved by the 50%.

  10. Measured Performance of a Varied Airflow Small-Diameter Duct System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Poerschke, Andrew

    2017-03-01

    This study tests the performance of a variable airflow small-diameter duct heating, ventilation, and air conditioning (HVAC) system in a new construction unoccupied low-load test house in Pittsburgh, Pennsylvania. The duct system was installed entirely in conditioned space and was operated from the winter through summer seasons. Measurements were collected on the in-room temperatures and energy consumed by the air handler and heat pump unit. Operation modes with three different volumes of airflow were compared to determine the ideal airflow scenario that maximizes room-to-room thermal uniformity while minimizing fan energy consumption. Black felt infrared imagery was used as a measuremore » of diffuser throw and in-room air mixing. Measured results indicate the small-diameter, high velocity airflow system can provide comfort under some conditions. Solar heat gains resulted in southern rooms drifting beyond acceptable temperature limits. Insufficient airflow to some bedrooms also resulted in periods of potential discomfort. Homebuilders or HVAC contractors can use these results to assess whether this space conditioning strategy is an attractive alternative to a traditional duct system. The team performed a cost analysis of two duct system configurations: (1) a conventional diameter and velocity duct system, and (2) the small-diameter duct system. This work applies to both new and retrofit homes that have achieved a low heating and cooling density either by energy conservation or by operation in a mild climate with few heating or cooling degree days. Guidance is provided on cost trade-offs between the conventional duct system and the small-diameter duct system.« less

  11. Measured Performance of a Varied Airflow Small-Diameter Duct System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Poerschke, Andrew

    This study tests the performance of a variable airflow small-diameter duct heating, ventilation, and air conditioning (HVAC) system in a new construction unoccupied low-load test house in Pittsburgh, Pennsylvania. The duct system was installed entirely in conditioned space and was operated from the winter through summer seasons. Measurements were collected on the in-room temperatures and energy consumed by the air handler and heat pump unit. Operation modes with three different volumes of airflow were compared to determine the ideal airflow scenario that maximizes room-to-room thermal uniformity while minimizing fan energy consumption. Black felt infrared imagery was used as a measuremore » of diffuser throw and in-room air mixing. Measured results indicate the small-diameter, high velocity airflow system can provide comfort under some conditions. Solar heat gains resulted in southern rooms drifting beyond acceptable temperature limits. Insufficient airflow to some bedrooms also resulted in periods of potential discomfort. Homebuilders or HVAC contractors can use these results to assess whether this space conditioning strategy is an attractive alternative to a traditional duct system. The team performed a cost analysis of two duct system configurations: (1) a conventional diameter and velocity duct system, and (2) the small-diameter duct system. This work applies to both new and retrofit homes that have achieved a low heating and cooling density either by energy conservation or by operation in a mild climate with few heating or cooling degree days. Guidance is provided on cost trade-offs between the conventional duct system and the small-diameter duct system.« less

  12. Building America Case Study: High-Velocity Small-Diameter Duct System, Pittsburgh, Pennsylvania

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    A. Poerschke

    This study tests the performance of a variable airflow small-diameter duct heating, ventilation, and air conditioning (HVAC) system in a new construction unoccupied low-load test house in Pittsburgh, Pennsylvania. The duct system was installed entirely in conditioned space and was operated from the winter through summer seasons. Measurements were collected on the in-room temperatures and energy consumed by the air handler and heat pump unit. Operation modes with three different volumes of airflow were compared to determine the ideal airflow scenario that maximizes room-to-room thermal uniformity while minimizing fan energy consumption. Black felt infrared imagery was used as a measuremore » of diffuser throw and in-room air mixing. Measured results indicate the small-diameter, high velocity airflow system can provide comfort under some conditions. Solar heat gains resulted in southern rooms drifting beyond acceptable temperature limits. Insufficient airflow to some bedrooms also resulted in periods of potential discomfort. Homebuilders or HVAC contractors can use these results to assess whether this space conditioning strategy is an attractive alternative to a traditional duct system. The team performed a cost analysis of two duct system configurations: (1) a conventional diameter and velocity duct system, and (2) the small-diameter duct system. This work applies to both new and retrofit homes that have achieved a low heating and cooling density either by energy conservation or by operation in a mild climate with few heating or cooling degree days. Guidance is provided on cost trade-offs between the conventional duct system and the small-diameter duct system.« less

  13. Single-mode annular chirally-coupled core fibers for fiber lasers

    NASA Astrophysics Data System (ADS)

    Zhang, Haitao; Hao, He; He, Linlu; Gong, Mali

    2018-03-01

    Chirally-coupled core (CCC) fiber can transmit single fundamental mode and effectively suppresses higher-order mode (HOM) propagation, thus improve the beam quality. However, the manufacture of CCC fiber is complicated due to its small side core. To decrease the manufacture difficulty in China, a novel fiber structure is presented, defined as annular chirally-coupled core (ACCC) fiber, replacing the small side core by a larger side annulus. In this paper, we designed the fiber parameters of this new structure, and demonstrated that the new structure has a similar property of single mode with traditional CCC fiber. Helical coordinate system was introduced into the finite element method (FEM) to analyze the mode field in the fiber, and the beam propagation method (BPM) was employed to analyze the influence of the fiber parameters on the mode loss. Based on the result above, the fiber structure was optimized for efficient single-mode transmission, in which the core diameter is 35 μm with beam quality M2 value of 1.04 and an optical to optical conversion efficiency of 84%. In this fiber, fundamental mode propagates in an acceptable loss, while the HOMs decay rapidly.

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    This study tests the performance of a variable airflow small-diameter duct heating, ventilation, and air conditioning (HVAC) system in a new construction unoccupied low-load test house in Pittsburgh, Pennsylvania. The duct system was installed entirely in conditioned space and was operated from the winter through summer seasons. Measurements were collected on the in-room temperatures and energy consumed by the air handler and heat pump unit. Operation modes with three different volumes of airflow were compared to determine the ideal airflow scenario that maximizes room-to-room thermal uniformity while minimizing fan energy consumption. Black felt infrared imagery was used as a measuremore » of diffuser throw and in-room air mixing. Measured results indicate the small-diameter, high velocity airflow system can provide comfort under some conditions. Solar heat gains resulted in southern rooms drifting beyond acceptable temperature limits. Insufficient airflow to some bedrooms also resulted in periods of potential discomfort. Homebuilders or HVAC contractors can use these results to assess whether this space conditioning strategy is an attractive alternative to a traditional duct system. The team performed a cost analysis of two duct system configurations: (1) a conventional diameter and velocity duct system, and (2) the small-diameter duct system. This work applies to both new and retrofit homes that have achieved a low heating and cooling density either by energy conservation or by operation in a mild climate with few heating or cooling degree days. Guidance is provided on cost trade-offs between the conventional duct system and the small-diameter duct system.« less

  15. An inexpensive and portable microvolumeter for rapid evaluation of biological samples.

    PubMed

    Douglass, John K; Wcislo, William T

    2010-08-01

    We describe an improved microvolumeter (MVM) for rapidly measuring volumes of small biological samples, including live zooplankton, embryos, and small animals and organs. Portability and low cost make this instrument suitable for widespread use, including at remote field sites. Beginning with Archimedes' principle, which states that immersing an arbitrarily shaped sample in a fluid-filled container displaces an equivalent volume, we identified procedures that maximize measurement accuracy and repeatability across a broad range of absolute volumes. Crucial steps include matching the overall configuration to the size of the sample, using reflected light to monitor fluid levels precisely, and accounting for evaporation during measurements. The resulting precision is at least 100 times higher than in previous displacement-based methods. Volumes are obtained much faster than by traditional histological or confocal methods and without shrinkage artifacts due to fixation or dehydration. Calibrations using volume standards confirmed accurate measurements of volumes as small as 0.06 microL. We validated the feasibility of evaluating soft-tissue samples by comparing volumes of freshly dissected ant brains measured with the MVM and by confocal reconstruction.

  16. Low-bending loss and single-mode operation in few-mode optical fiber

    NASA Astrophysics Data System (ADS)

    Yin, Ping; Wang, Hua; Chen, Ming-Yang; Wei, Jin; Cai, Zhi-Min; Li, Lu-Ming; Yang, Ji-Hai; Zhu, Yuan-Feng

    2016-10-01

    The technique of eliminating the higher-order modes in a few-mode optical fiber is proposed. The fiber is designed with a group of defect modes in the cladding. The higher-order modes in the fiber can be eliminated by bending the fiber to induce strong coupling between the defect modes and the higher-order modes. Numerical simulation shows the bending losses of the LP01 mode are lower than 1.5×10-4 dB/turn for the wavelength shorter than 1.625 μm. The proposed fiber can be bent multiple turns at small bending radius which are preferable for FTTH related applications.

  17. In Vivo High-Frequency Contrast-Enhanced Ultrasonography of Choroidal Melanoma in Rabbits: Imaging Features and Histopathologic Correlations

    PubMed Central

    Kang, Shin J.; Zhang, Qing; Patel, Samirkumar R.; Berezovsky, Damian; Yang, Hua; Wang, Yanggan; Grossniklaus, Hans E.

    2013-01-01

    Purpose To evaluate the utility of in vivo imaging of rabbit model of choroidal melanoma utilizing high-frequency contrast-enhanced ultrasound (HF-CE-US) with 2-or 3-dimensional modes, and to correlate the sonographic findings with histopathologic characteristics. Methods Five New Zealand white rabbits which were immunosuppressed with daily cyclosporin A were inoculated into their right eyes with aliquots of 1.5×106 / 50 µL of 92.1 human uveal melanoma cells cultured in RPMI. At week 4, the tumor-bearing eyes were imaged using high-frequency ultrasound with microbubble contrast agent to determine the 2-dimensional tumor size and relative blood volume and by 3-dimensional mode to determine tumor volume. Histologic tumor burden was quantified in enucleated eyes by ImageJ software, and microvascular density (MVD) was determined by counting vascular channels in PAS without hematoxylin sections. Results Utilizing HF-CE-US, melanomas were visualized as relatively hyperechoic regions in the images. The correlation coefficients of sonographic size or volume compared with histologic area were 0.72 and 0.70, respectively. The sonographic tumor relative blood volume correlated with the histologic tumor vascularity (R2=0.92, P=0.04) Conclusions There is a positive correlation between in vivo sonographic tumor volume/size and histologic tumor size in our rabbit choroidal melanoma model. HF-CE-US corresponds to microvascular density and blood volume. PMID:23645822

  18. The Different Volume Effects of Small-Bowel Toxicity During Pelvic Irradiation Between Gynecologic Patients With and Without Abdominal Surgery: A Prospective Study With Computed Tomography-Based Dosimetry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, E.-Y.; Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Kaohsiung, Taiwan; School of Traditional Chinese Medicine, Chang Gung University College of Medicine, Kaohsiung, Taiwan

    Purpose: To evaluate the effect of abdominal surgery on the volume effects of small-bowel toxicity during whole-pelvic irradiation in patients with gynecologic malignancies. Methods and Materials: From May 2003 through November 2006, 80 gynecologic patients without (Group I) or with (Group II) prior abdominal surgery were analyzed. We used a computed tomography (CT) planning system to measure the small-bowel volume and dosimetry. We acquired the range of small-bowel volume in 10% (V10) to 100% (V100) of dose, at 10% intervals. The onset and grade of diarrhea during whole-pelvic irradiation were recorded as small-bowel toxicity up to 39.6 Gy in 22more » fractions. Results: The volume effect of Grade 2-3 diarrhea existed from V10 to V100 in Group I patients and from V60 to V100 in Group II patients on univariate analyses. The V40 of Group I and the V100 of Group II achieved most statistical significance. The mean V40 was 281 {+-} 27 cm{sup 3} and 489 {+-} 34 cm{sup 3} (p < 0.001) in Group I patients with Grade 0-1 and Grade 2-3 diarrhea, respectively. The corresponding mean V100 of Group II patients was 56 {+-} 14 cm{sup 3} and 132 {+-} 19 cm{sup 3} (p = 0.003). Multivariate analyses revealed that V40 (p = 0.001) and V100 (p = 0.027) were independent factors for the development of Grade 2-3 diarrhea in Groups I and II, respectively. Conclusions: Gynecologic patients without and with abdominal surgery have different volume effects on small-bowel toxicity during whole-pelvic irradiation. Low-dose volume can be used as a predictive index of Grade 2 or greater diarrhea in patients without abdominal surgery. Full-dose volume is more important than low-dose volume for Grade 2 or greater diarrhea in patients with abdominal surgery.« less

  19. Measuring pedestrian volumes and conflicts. Volume 1, Pedestrian volume sampling

    DOT National Transportation Integrated Search

    1987-12-01

    This final report presents the findings, conclusions, and recommendations of the study conducted to develop a model to predict pedestrian volumes using small sampling schemes. This research produced four pedestrian volume prediction models (i.e., 1-,...

  20. Impedance Eduction in Large Ducts Containing Higher-Order Modes and Grazing Flow

    NASA Technical Reports Server (NTRS)

    Watson, Willie R.; Jones, Michael G.

    2017-01-01

    Impedance eduction test data are acquired in ducts with small and large cross-sectional areas at the NASA Langley Research Center. An improved data acquisition system in the large duct has resulted in increased control of the acoustic energy in source modes and more accurate resolution of higher-order duct modes compared to previous tests. Two impedance eduction methods that take advantage of the improved data acquisition to educe the liner impedance in grazing flow are presented. One method measures the axial propagation constant of a dominant mode in the liner test section (by implementing the Kumarsean and Tufts algorithm) and educes the impedance from an exact analytical expression. The second method solves numerically the convected Helmholtz equation and minimizes an objective function to obtain the liner impedance. The two methods are tested first on data synthesized from an exact mode solution and then on measured data. Results show that when the methods are applied to data acquired in the larger duct with a dominant higher-order mode, the same impedance spectra are educed as that obtained in the small duct where only the plane wave mode propagates. This result holds for each higher-order mode in the large duct provided that the higher-order mode is sufficiently attenuated by the liner.

  1. Mechanistic Fluid Transport Model to Estimate Gastrointestinal Fluid Volume and Its Dynamic Change Over Time.

    PubMed

    Yu, Alex; Jackson, Trachette; Tsume, Yasuhiro; Koenigsknecht, Mark; Wysocki, Jeffrey; Marciani, Luca; Amidon, Gordon L; Frances, Ann; Baker, Jason R; Hasler, William; Wen, Bo; Pai, Amit; Sun, Duxin

    2017-11-01

    Gastrointestinal (GI) fluid volume and its dynamic change are integral to study drug disintegration, dissolution, transit, and absorption. However, key questions regarding the local volume and its absorption, secretion, and transit remain unanswered. The dynamic fluid compartment absorption and transit (DFCAT) model is proposed to estimate in vivo GI volume and GI fluid transport based on magnetic resonance imaging (MRI) quantified fluid volume. The model was validated using GI local concentration of phenol red in human GI tract, which was directly measured by human GI intubation study after oral dosing of non-absorbable phenol red. The measured local GI concentration of phenol red ranged from 0.05 to 168 μg/mL (stomach), to 563 μg/mL (duodenum), to 202 μg/mL (proximal jejunum), and to 478 μg/mL (distal jejunum). The DFCAT model characterized observed MRI fluid volume and its dynamic changes from 275 to 46.5 mL in stomach (from 0 to 30 min) with mucus layer volume of 40 mL. The volumes of the 30 small intestine compartments were characterized by a max of 14.98 mL to a min of 0.26 mL (0-120 min) and a mucus layer volume of 5 mL per compartment. Regional fluid volumes over 0 to 120 min ranged from 5.6 to 20.38 mL in the proximal small intestine, 36.4 to 44.08 mL in distal small intestine, and from 42 to 64.46 mL in total small intestine. The DFCAT model can be applied to predict drug dissolution and absorption in the human GI tract with future improvements.

  2. A Better MOC Index: AMOC-θ/S in the North Atlantic Ocean: Spatial Circulation, Water-mass Transformation and Heat Transport on the Temperature/Salinity Plane

    NASA Astrophysics Data System (ADS)

    Rhines, P. B.; Xu, X.; Chassignet, E.; Schmitz, W. J., Jr.

    2016-02-01

    An eddy-resolving HYCOM circulation model (driven by a reanalysis atmosphere) shows the structure of the North Atlantic meridional overturning circulation (AMOC), heat transport (MHT) and freshwater transport (MFWT). We project the zonal-mean lateral volume transport, called V(θ,S,y), onto the potential temperature/salinity (θ/S-) plane, and `collapse' V into four zonally integrated volume-transport stream-functions with respect to potential density σ, θ, S and vertical coordinate. The figure shows V(θ,S,y) at 4 latitudes, y, labeled a-d, with northward volume transport in red, southward in blue; Sverdrups of transport are inscribed in σ-bands. Collapsing V onto overturning streamfunctions loses the connection with classic water masses, the hydrologic cycle and convective mode-water production. It is essential that the model resolve boundary currents and the dense northern overflows: model and observations show the dominance of basin-scale AMOC in both MHT and MFWT with potential density, σ, as the vertical coordinate... but much less so with z as a vertical coordinate. With adequate resolution of deep sinking, the Lower North Atlantic Deep Water contributes significantly to MHT. Time-mean MHT and MFWT are dominated by 5-year mean-fields: contributions from annual cycles of velocity and θ are surprisingly small. Quantitative comparison between model and observations at 26N and in the subpolar gyre is supportive of these results. Yet isopycnal processes involving lateral gyres and wind forcing are important. They concentrate the activity of the MOC near western boundaries where essential water-mass transformation (WMT) takes place. V(θ,S,y) transport adds thermohaline `spice' to the MOC, revealing both isopycnal and diapycnal mixing and transport and connects directly with classical water masses. 3-dimensional maps of diapycnal and isopycnal mixing/transport connect internal and externally driven WMT and transports. Particularly important transformation sites are the downslope overflow regions, boundary current extensions (Gulf Stream/North Atlantic Current), mode-water convection sites, deep western boundary currents where topographic transitions occur, and frontal regions (Newfoundland Basin) where northward and southward AMOC branches brush against one another.

  3. Volume measurement of cryogenic deuterium pellets by Bayesian analysis of single shadowgraphy images

    NASA Astrophysics Data System (ADS)

    Szepesi, T.; Kálvin, S.; Kocsis, G.; Lang, P. T.; Wittmann, C.

    2008-03-01

    In situ commissioning of the Blower-gun injector for launching cryogenic deuterium pellets at ASDEX Upgrade tokamak was performed. This injector is designed for high repetitive launch of small pellets for edge localised modes pacing experiments. During the investigation the final injection geometry was simulated with pellets passing to the torus through a 5.5m long guiding tube. For investigation of pellet quality at launch and after tube passage laser flash camera shadowgraphy diagnostic units before and after the tube were installed. As indicator of pellet quality we adopted the pellet mass represented by the volume of the main remaining pellet fragment. Since only two-dimensional (2D) shadow images were obtained, a reconstruction of the full three-dimensional pellet body had to be performed. For this the image was first converted into a 1-bit version prescribing an exact 2D contour. From this contour the expected value of the volume was calculated by Bayesian analysis taking into account the likely cylindrical shape of the pellet. Under appropriate injection conditions sound pellets with more than half of their nominal mass are detected after acceleration; the passage causes in average an additional loss of about 40% to the launched mass. Analyzing pellets arriving at tube exit allowed for deriving the injector's optimized operational conditions. For these more than 90% of the pellets were arriving with sound quality when operating in the frequency range 5-50Hz.

  4. Microbleeds versus macrobleeds: evidence for distinct entities.

    PubMed

    Greenberg, Steven M; Nandigam, R N Kaveer; Delgado, Pilar; Betensky, Rebecca A; Rosand, Jonathan; Viswanathan, Anand; Frosch, Matthew P; Smith, Eric E

    2009-07-01

    Small, asymptomatic microbleeds commonly accompany larger symptomatic macrobleeds. It is unclear whether microbleeds and macrobleeds represent arbitrary categories within a single continuum versus truly distinct events with separate pathophysiologies. We performed 2 complementary retrospective analyses. In a radiographic analysis, we measured and plotted the volumes of all hemorrhagic lesions detected by gradient-echo MRI among 46 consecutive patients with symptomatic primary lobar intracerebral hemorrhage diagnosed as probable or possible cerebral amyloid angiopathy. In a second neuropathologic analysis, we performed blinded qualitative and quantitative examinations of amyloid-positive vessel segments in 6 autopsied subjects whose MRI scans demonstrated particularly high microbleed counts (>50 microbleeds on MRI, n=3) or low microbleed counts (<3 microbleeds, n=3). Plotted on a logarithmic scale, the volumes of 163 hemorrhagic lesions identified on scans from the 46 subjects fell in a distinctly bimodal distribution with mean volumes for the 2 modes of 0.009 cm(3) and 27.5 cm(3). The optimal cut point for separating the 2 peaks (determined by receiver operating characteristics) corresponded to a lesion diameter of 0.57 cm. On neuropathologic analysis, the high microbleed-count autopsied subjects showed significantly thicker amyloid-positive vessel walls than the low microbleed-count subjects (proportional wall thickness 0.53+/-0.01 versus 0.37+/-0.01; P<0.0001; n=333 vessel segments analyzed). These findings suggest that cerebral amyloid angiopathy-associated microbleeds and macrobleeds comprise distinct entities. Increased vessel wall thickness may predispose to formation of microbleeds relative to macrobleeds.

  5. Microbleeds versus Macrobleeds: Evidence for Distinct Entities

    PubMed Central

    Greenberg, SM; Nandigam, RNK; Delgado, P; Betensky, RA; Rosand, J; Viswanathan, A; Frosch, MP; Smith, EE

    2009-01-01

    Background and Purpose Small, asymptomatic microbleeds commonly accompany larger symptomatic macrobleeds. It is unclear whether microbleeds and macrobleeds represent arbitrary categories within a single continuum versus truly distinct events with separate pathophysiologies. Methods We performed two complementary retrospective analyses. In a radiographic analysis, we measured and plotted the volumes of all hemorrhagic lesions detected by gradient-echo MRI among 46 consecutive patients with symptomatic primary lobar intracerebral hemorrhage diagnosed as probable or possible cerebral amyloid angiopathy (CAA). In a second neuropathologic analysis, we performed blinded qualitative and quantitative examinations of amyloid-positive vessel segments in 6 autopsied subjects whose MRI scans demonstrated particularly high microbleed counts (>50 microbleeds on MRI, n=3) or low microbleed counts (<3 microbleeds, n=3). Results Plotted on a logarithmic scale, the volumes of 163 hemorrhagic lesions identified on scans from the 46 subjects fell in a distinctly bimodal distribution with mean volumes for the two modes of 0.009 cm3 and 27.5 cm3. The optimal cut-point for separating the two peaks (determined by receiver operating characteristics) corresponded to a lesion diameter of 0.57 cm. On neuropathologic analysis, the high microbleed-count autopsied subjects showed significantly thicker amyloid-positive vessel walls than the low microbleed-count subjects (proportional wall thickness 0.53±0.01 versus 0.37±0.01, p<.0001, n=333 vessel segments analyzed). Conclusions These findings suggest that CAA-associated microbleeds and macrobleeds comprise distinct entities. Increased vessel wall thickness may predispose to formation of microbleeds relative to macrobleeds. PMID:19443797

  6. Three-dimensional single-mode nonlinear ablative Rayleigh-Taylor instability

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yan, R.; Aluie, H.; Laboratory for Laser Energetics, University of Rochester, Rochester, New York 14627

    The nonlinear evolution of the single-mode ablative Rayleigh-Taylor instability is studied in three dimensions. As the mode wavelength approaches the cutoff of the linear spectrum (short-wavelength modes), it is found that the three-dimensional (3D) terminal bubble velocity greatly exceeds both the two-dimensional (2D) value and the classical 3D bubble velocity. Unlike in 2D, the 3D short-wavelength bubble velocity does not saturate. The growing 3D bubble acceleration is driven by the unbounded accumulation of vorticity inside the bubble. The vorticity is transferred by mass ablation from the Rayleigh-Taylor spikes to the ablated plasma filling the bubble volume.

  7. Dynamic characteristics of a hydrostatic gas bearing driven by oscillating exhaust pressure

    NASA Technical Reports Server (NTRS)

    Watkins, C. B.; Eronini, I. E.; Branch, H. D.

    1984-01-01

    Vibration of a statically loaded, inherently compensated hydrostatic journal bearing due to oscillating exhaust pressure is investigated. Both angular and radial vibration modes are analyzed. The time-dependent Reynolds equation governing the pressure distribution between the oscillating journal and sleeve is solved together with the journal equation of motion to obtain the response characteristics of the bearing. The Reynolds equation and the equation of motion are simplified by applying regular perturbation theory for small displacements. The numerical solutions of the perturbation equations are obtained by discretizing the pressure field using finite-difference aproximations with a discrete, nonuniform line-source model which excludes effects due to feeding hole volume. An iterative scheme is used to simultaneously satisfy the equations of motion for the journal. The results presented include Bode plots of bearing-oscillation gain and phase for a particular bearing configuration for various combinations of parameters over a range of frequencies, including the resonant frequency.

  8. SERS of Individual Nanoparticles on a Mirror: Size Does Matter, but so Does Shape

    PubMed Central

    2016-01-01

    Coupling noble metal nanoparticles by a 1 nm gap to an underlying gold mirror confines light to extremely small volumes, useful for sensing on the nanoscale. Individually measuring 10 000 of such gold nanoparticles of increasing size dramatically shows the different scaling of their optical scattering (far-field) and surface-enhanced Raman emission (SERS, near-field). Linear red-shifts of the coupled plasmon modes are seen with increasing size, matching theory. The total SERS from the few hundred molecules under each nanoparticle dramatically increases with increasing size. This scaling shows that maximum SERS emission is always produced from the largest nanoparticles, irrespective of tuning to any plasmonic resonances. Changes of particle facet with nanoparticle size result in vastly weaker scaling of the near-field SERS, without much modifying the far-field, and allows simple approaches for optimizing practical sensing. PMID:27223478

  9. SERS of Individual Nanoparticles on a Mirror: Size Does Matter, but so Does Shape.

    PubMed

    Benz, Felix; Chikkaraddy, Rohit; Salmon, Andrew; Ohadi, Hamid; de Nijs, Bart; Mertens, Jan; Carnegie, Cloudy; Bowman, Richard W; Baumberg, Jeremy J

    2016-06-16

    Coupling noble metal nanoparticles by a 1 nm gap to an underlying gold mirror confines light to extremely small volumes, useful for sensing on the nanoscale. Individually measuring 10 000 of such gold nanoparticles of increasing size dramatically shows the different scaling of their optical scattering (far-field) and surface-enhanced Raman emission (SERS, near-field). Linear red-shifts of the coupled plasmon modes are seen with increasing size, matching theory. The total SERS from the few hundred molecules under each nanoparticle dramatically increases with increasing size. This scaling shows that maximum SERS emission is always produced from the largest nanoparticles, irrespective of tuning to any plasmonic resonances. Changes of particle facet with nanoparticle size result in vastly weaker scaling of the near-field SERS, without much modifying the far-field, and allows simple approaches for optimizing practical sensing.

  10. Evidence for hubs in human functional brain networks

    PubMed Central

    Power, Jonathan D; Schlaggar, Bradley L; Lessov-Schlaggar, Christina N; Petersen, Steven E

    2013-01-01

    Summary Hubs integrate and distribute information in powerful ways due to the number and positioning of their contacts in a network. Several resting state functional connectivity MRI reports have implicated regions of the default mode system as brain hubs; we demonstrate that previous degree-based approaches to hub identification may have identified portions of large brain systems rather than critical nodes of brain networks. We utilize two methods to identify hub-like brain regions: 1) finding network nodes that participate in multiple sub-networks of the brain, and 2) finding spatial locations where several systems are represented within a small volume. These methods converge on a distributed set of regions that differ from previous reports on hubs. This work identifies regions that support multiple systems, leading to spatially constrained predictions about brain function that may be tested in terms of lesions, evoked responses, and dynamic patterns of activity. PMID:23972601

  11. A new blood pump for cardiopulmonary bypass: the HiFlow centrifugal pump.

    PubMed

    Göbel, C; Eilers, R; Reul, H; Schwindke, P; Jörger, M; Rau, G

    1997-07-01

    Centrifugal blood pumps are considered to be generally superior to the traditionally used roller pumps in cardiopulmonary bypass. In our institute a new lightweight centrifugal sealless blood pump with a unique spherical thrust bearing and with a magnetic coupling was developed, the HiFlow. The small design makes the pump suitable for applications in complex devices or close to a patient. Hemolysis tests were carried out in which the BioMedicus pump BP-80 and a roller pump were used as reference. The centrifugal pump HiFlow showed the least blood trauma within the group of investigated pumps. In summary, the HiFlow pump concept with its low priming volume and limited contact surfaces shows great potential for clinical applications in cardiopulmonary bypass. Also, the possibility of using the pump as a short-term assist device with an option of a pulsatile driving mode was demonstrated.

  12. A compact 3 T all HTS cryogen-free MRI system

    NASA Astrophysics Data System (ADS)

    Parkinson, B. J.; Bouloukakis, K.; Slade, R. A.

    2017-12-01

    We have designed and built a passively shielded, cryogen-free 3 T 160 mm bore bismuth strontium calcium copper oxide HTS magnet with shielded gradient coils suitable for use in small animal imaging applications. The magnet is cooled to approximately 16 K using a two-stage cryocooler and is operated at 200 A. The magnet has been passively shimmed so as to achieve ±10 parts per million (ppm) homogeneity over a 60 mm diameter imaging volume. We have demonstrated that B 0 temporal stability is fit-for-purpose despite the magnet operating in the driven mode. The system has produced good quality spin-echo and gradient echo images. This compact HTS-MRI system is emerging as a true alternative to conventional low temperature superconductor based cryogen-free MRI systems, with much more efficient cryogenics since it operates entirely from a single phase alternating current electrical supply.

  13. Low cost silicon solar array project silicon materials task: Establishment of the feasibility of a process capable of low-cost, high volume production of silane (step 1) and the pyrolysis of silane to semiconductor-grade silicon (step 2)

    NASA Technical Reports Server (NTRS)

    Breneman, W. C.; Farrier, E. G.; Rexer, J.

    1977-01-01

    Extended operation of a small process-development unit routinely produced high quality silane in 97+% yield from dichlorosilane. The production rate was consistent with design loadings for the fractionating column and for the redistribution reactor. A glass fluid-bed reactor was constructed for room temperature operation. The behavior of a bed of silcon particles was observed as a function of various feedstocks, component configurations, and operating conditions. For operating modes other than spouting, the bed behaved in an erratic and unstable manner. A method was developed for casting molten silicon powder into crack-free solid pellets for process evaluation. The silicon powder was melted and cast into thin walled quartz tubes that sacrificially broke on cooling.

  14. The onset of electrospray: the universal scaling laws of the first ejection

    PubMed Central

    Gañán-Calvo, A. M.; López-Herrera, J. M.; Rebollo-Muñoz, N.; Montanero, J. M.

    2016-01-01

    The disintegration of liquid drops with low electrical conductivity and subject to an electric field is investigated both theoretically and experimentally. This disintegration takes place through the development of a conical cusp that eventually ejects an ultrathin liquid ligament. A first tiny drop is emitted from the end of this ligament. Due to its exceptionally small size and large electric charge per unit volume, that drop has been the object of relevant recent studies. In this paper, universal scaling laws for the diameter and electric charge of the first issued droplet are proposed and validated both numerically and experimentally. Our analysis shows how charge relaxation is the mechanism that differentiates the onset of electrospray, including the first droplet ejection, from the classical steady cone-jet mode. In this way, our study identifies when and where charge relaxation and electrokinetic phenomena come into play in electrospray, a subject of live controversy in the field. PMID:27581554

  15. Enhanced magnetic Purcell effect in room-temperature masers

    PubMed Central

    Breeze, Jonathan; Tan, Ke-Jie; Richards, Benjamin; Sathian, Juna; Oxborrow, Mark; Alford, Neil McN

    2015-01-01

    Recently, the world’s first room-temperature maser was demonstrated. The maser consisted of a sapphire ring housing a crystal of pentacene-doped p-terphenyl, pumped by a pulsed rhodamine-dye laser. Stimulated emission of microwaves was aided by the high quality factor and small magnetic mode volume of the maser cavity yet the peak optical pumping power was 1.4 kW. Here we report dramatic miniaturization and 2 orders of magnitude reduction in optical pumping power for a room-temperature maser by coupling a strontium titanate resonator with the spin-polarized population inversion provided by triplet states in an optically excited pentacene-doped p-terphenyl crystal. We observe maser emission in a thimble-sized resonator using a xenon flash lamp as an optical pump source with peak optical power of 70 W. This is a significant step towards the goal of continuous maser operation. PMID:25698634

  16. Dual capacity reciprocating compressor

    DOEpatents

    Wolfe, Robert W.

    1984-01-01

    A multi-cylinder compressor 10 particularly useful in connection with northern climate heat pumps and in which different capacities are available in accordance with reversing motor 16 rotation is provided with an eccentric cam 38 on a crank pin 34 under a fraction of the connecting rods, and arranged for rotation upon the crank pin between opposite positions 180.degree. apart so that with cam rotation on the crank pin such that the crank throw is at its normal maximum value all pistons pump at full capacity, and with rotation of the crank shaft in the opposite direction the cam moves to a circumferential position on the crank pin such that the overall crank throw is zero. Pistons 24 whose connecting rods 30 ride on a crank pin 36 without a cam pump their normal rate with either crank rotational direction. Thus a small clearance volume is provided for any piston that moves when in either capacity mode of operation.

  17. Dual capacity reciprocating compressor

    DOEpatents

    Wolfe, R.W.

    1984-10-30

    A multi-cylinder compressor particularly useful in connection with northern climate heat pumps and in which different capacities are available in accordance with reversing motor rotation is provided with an eccentric cam on a crank pin under a fraction of the connecting rods, and arranged for rotation upon the crank pin between opposite positions 180[degree] apart so that with cam rotation on the crank pin such that the crank throw is at its normal maximum value all pistons pump at full capacity, and with rotation of the crank shaft in the opposite direction the cam moves to a circumferential position on the crank pin such that the overall crank throw is zero. Pistons whose connecting rods ride on a crank pin without a cam pump their normal rate with either crank rotational direction. Thus a small clearance volume is provided for any piston that moves when in either capacity mode of operation. 6 figs.

  18. Improvements in ion reflux: An electrodialytic eluent generation and suppression device for ion chromatography.

    PubMed

    Elkin, Kyle; Riviello, John; Small, Hamish

    2015-07-17

    This work describes a membrane based electrodialytic ion reflux device (IRD), which uses water as the pumped phase and integrates isocratic and gradient eluent generation and suppression. The current design incorporates several ion exchange membranes to create discrete chambers for suppression and eluent generation, while isolating the electrodes from the analytical stream. A small volume of recycled water can be used as the pumped phase while continuously refluxing the eluent ions. This current design permits electronically controlled eluent generation of at least 16.4μeq KOHmin(-1), while maintaining low suppressed background conductivity (<0.5μS/cm). The device was operated in gradient or isocratic mode continuously for up to 6 weeks. During this period, over 500 gradient and isocratic injections were performed, showing peak retention time precision below 1.5% RSD. Published by Elsevier B.V.

  19. Impact of various operating modes on performance and emission parameters of small heat source

    NASA Astrophysics Data System (ADS)

    Vician, Peter; Holubčík, Michal; Palacka, Matej; Jandačka, Jozef

    2016-06-01

    Thesis deals with the measurement of performance and emission parameters of small heat source for combustion of biomass in each of its operating modes. As the heat source was used pellet boiler with an output of 18 kW. The work includes design of experimental device for measuring the impact of changes in air supply and method for controlling the power and emission parameters of heat sources for combustion of woody biomass. The work describes the main factors that affect the combustion process and analyze the measurements of emissions at the heat source. The results of experiment demonstrate the values of performance and emissions parameters for the different operating modes of the boiler, which serve as a decisive factor in choosing the appropriate mode.

  20. Cargo/Logistics Airlift System Study (CLASS), Volume 1

    NASA Technical Reports Server (NTRS)

    Norman, J. M.; Henderson, R. D.; Macey, F. C.; Tuttle, R. P.

    1978-01-01

    Current and advanced air cargo systems are evaluated using industrial and consumer statistics. Market and commodity characteristics that influence the use of the air mode are discussed along with a comparison of air and surface mode on typical routes. Results of on-site surveys of cargo processing facilities at airports are presented, and institutional controls and influences on air cargo operations are considered.

  1. Failure mode analysis for lime/limestone FGD system. Volume III. Plant profiles. Part 1 of 3

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kenney, S.M.; Rosenberg, H.S.; Nilsson, L.I.O.

    1984-08-01

    This volume contains plant profiles for: Petersburg 3; Hawthorn 3, 4; La Cygne 1; Jeffry 1, 2; Lawrence 4, 5; Green River 1-3; Cane Run 4, 5; Mill Creek 1, 3; Paddy's Run 6; Clay Boswell 4; Milton R. Young 2; Pleasants 1, 2; and Colstrip 1, 2. (DLC)

  2. Waveguides for performing enzymatic reactions

    DOEpatents

    Levene; Michael J. , Korlach; Jonas , Turner; Stephen W. , Craighead; Harold G. , Webb; Watt W.

    2007-11-06

    The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode wave guide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide.

  3. Discrete mode laser diodes for FTTH/PON applications up to 10 Gbit/s

    NASA Astrophysics Data System (ADS)

    O'Carroll, John; Phelan, Richard; Kelly, Brian; Byrne, Diarmuid; Latkowski, Sylwester; Anandarajah, Prince M.; Barry, Liam P.

    2012-06-01

    Discrete Mode Laser Diodes (DMLDs) present an economic approach with a focus on high volume manufacturability of single mode lasers using a single step fabrication process. We report on a DMLD designed for operation in the 1550 nm window with high Side Mode Suppression Ratio (SMSR) over a wide temperature tuning range of -20 °C < T < 95 °C. Direct modulation rates as high as 10 Gbit/s are demonstrated at both 1550 nm and 1310 nm. Transmission experiments were also carried out over single mode fibre at both wavelengths. Using dispersion pre-compensation transmission from 0 to 60 km is demonstrated at 1550 nm with a maximum power penalty measured at 60 km of 3.6 dB.

  4. Elastic Moduli and Damping of Vibrational Modes of Aluminum/Silicon Carbide Composite Beams

    NASA Technical Reports Server (NTRS)

    Leidecker, Henning

    1996-01-01

    Elastic and shear moduli were determined for two aluminum matrix composites containing 20 and 40 volume percent discontinuous silicon carbide, respectively, using transverse, longitudinal, and torsional vibrational modes of specimens prepared as thin beams. These moduli are consistent with those determined from stress-strain measurements. The damping factors for these modes were also determined. Thermal properties are used to show that part of the damping of transverse modes is caused by the transverse thermal currents discussed by C. Zener (thermo-elastic damping); this damping is frequency-dependent with a maximum damping factor of approximately 0.002. The remaining damping is frequency-independent, and has roughly similar values in transverse, longitudinal, and torsional modes: approximately 0.0001.

  5. Synthetic calibration of a Rainfall-Runoff Model

    USGS Publications Warehouse

    Thompson, David B.; Westphal, Jerome A.; ,

    1990-01-01

    A method for synthetically calibrating storm-mode parameters for the U.S. Geological Survey's Precipitation-Runoff Modeling System is described. Synthetic calibration is accomplished by adjusting storm-mode parameters to minimize deviations between the pseudo-probability disributions represented by regional regression equations and actual frequency distributions fitted to model-generated peak discharge and runoff volume. Results of modeling storm hydrographs using synthetic and analytic storm-mode parameters are presented. Comparisons are made between model results from both parameter sets and between model results and observed hydrographs. Although mean storm runoff is reproducible to within about 26 percent of the observed mean storm runoff for five or six parameter sets, runoff from individual storms is subject to large disparities. Predicted storm runoff volume ranged from 2 percent to 217 percent of commensurate observed values. Furthermore, simulation of peak discharges was poor. Predicted peak discharges from individual storm events ranged from 2 percent to 229 percent of commensurate observed values. The model was incapable of satisfactorily executing storm-mode simulations for the study watersheds. This result is not considered a particular fault of the model, but instead is indicative of deficiencies in similar conceptual models.

  6. Electron-cyclotron wave propagation, absorption and current drive in the presence of neoclassical tearing modes

    NASA Astrophysics Data System (ADS)

    Isliker, Heinz; Chatziantonaki, Ioanna; Tsironis, Christos; Vlahos, Loukas

    2012-09-01

    We analyze the propagation of electron-cyclotron waves, their absorption and current drive when neoclassical tearing modes (NTMs), in the form of magnetic islands, are present in a tokamak plasma. So far, the analysis of the wave propagation and power deposition in the presence of NTMs has been performed mainly in the frame of an axisymmetric magnetic field, ignoring any effects from the island topology. Our analysis starts from an axisymmetric magnetic equilibrium, which is perturbed such as to exhibit magnetic islands. In this geometry, we compute the wave evolution with a ray-tracing code, focusing on the effect of the island topology on the efficiency of the absorption and current drive. To increase the precision in the calculation of the power deposition, the standard analytical flux-surface labeling for the island region has been adjusted from the usual cylindrical to toroidal geometry. The propagation up to the O-point is found to be little affected by the island topology, whereas the power absorbed and the driven current are significantly enhanced, because the resonant particles are bound to the small volumes in between the flux surfaces of the island. The consequences of these effects on the NTM evolution are investigated in terms of the modified Rutherford equation.

  7. Research of Planetary Gear Fault Diagnosis Based on Permutation Entropy of CEEMDAN and ANFIS

    PubMed Central

    Kuai, Moshen; Cheng, Gang; Li, Yong

    2018-01-01

    For planetary gear has the characteristics of small volume, light weight and large transmission ratio, it is widely used in high speed and high power mechanical system. Poor working conditions result in frequent failures of planetary gear. A method is proposed for diagnosing faults in planetary gear based on permutation entropy of Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (CEEMDAN) Adaptive Neuro-fuzzy Inference System (ANFIS) in this paper. The original signal is decomposed into 6 intrinsic mode functions (IMF) and residual components by CEEMDAN. Since the IMF contains the main characteristic information of planetary gear faults, time complexity of IMFs are reflected by permutation entropies to quantify the fault features. The permutation entropies of each IMF component are defined as the input of ANFIS, and its parameters and membership functions are adaptively adjusted according to training samples. Finally, the fuzzy inference rules are determined, and the optimal ANFIS is obtained. The overall recognition rate of the test sample used for ANFIS is 90%, and the recognition rate of gear with one missing tooth is relatively high. The recognition rates of different fault gears based on the method can also achieve better results. Therefore, the proposed method can be applied to planetary gear fault diagnosis effectively. PMID:29510569

  8. Metal-Insulator-Metal-Based Plasmonic Metamaterial Absorbers at Visible and Infrared Wavelengths: A Review.

    PubMed

    Ogawa, Shinpei; Kimata, Masafumi

    2018-03-20

    Electromagnetic wave absorbers have been investigated for many years with the aim of achieving high absorbance and tunability of both the absorption wavelength and the operation mode by geometrical control, small and thin absorber volume, and simple fabrication. There is particular interest in metal-insulator-metal-based plasmonic metamaterial absorbers (MIM-PMAs) due to their complete fulfillment of these demands. MIM-PMAs consist of top periodic micropatches, a middle dielectric layer, and a bottom reflector layer to generate strong localized surface plasmon resonance at absorption wavelengths. In particular, in the visible and infrared (IR) wavelength regions, a wide range of applications is expected, such as solar cells, refractive index sensors, optical camouflage, cloaking, optical switches, color pixels, thermal IR sensors, IR microscopy and gas sensing. The promising properties of MIM-PMAs are attributed to the simple plasmonic resonance localized at the top micropatch resonators formed by the MIMs. Here, various types of MIM-PMAs are reviewed in terms of their historical background, basic physics, operation mode design, and future challenges to clarify their underlying basic design principles and introduce various applications. The principles presented in this review paper can be applied to other wavelength regions such as the ultraviolet, terahertz, and microwave regions.

  9. Metal-Insulator-Metal-Based Plasmonic Metamaterial Absorbers at Visible and Infrared Wavelengths: A Review

    PubMed Central

    Ogawa, Shinpei; Kimata, Masafumi

    2018-01-01

    Electromagnetic wave absorbers have been investigated for many years with the aim of achieving high absorbance and tunability of both the absorption wavelength and the operation mode by geometrical control, small and thin absorber volume, and simple fabrication. There is particular interest in metal-insulator-metal-based plasmonic metamaterial absorbers (MIM-PMAs) due to their complete fulfillment of these demands. MIM-PMAs consist of top periodic micropatches, a middle dielectric layer, and a bottom reflector layer to generate strong localized surface plasmon resonance at absorption wavelengths. In particular, in the visible and infrared (IR) wavelength regions, a wide range of applications is expected, such as solar cells, refractive index sensors, optical camouflage, cloaking, optical switches, color pixels, thermal IR sensors, IR microscopy and gas sensing. The promising properties of MIM-PMAs are attributed to the simple plasmonic resonance localized at the top micropatch resonators formed by the MIMs. Here, various types of MIM-PMAs are reviewed in terms of their historical background, basic physics, operation mode design, and future challenges to clarify their underlying basic design principles and introduce various applications. The principles presented in this review paper can be applied to other wavelength regions such as the ultraviolet, terahertz, and microwave regions. PMID:29558454

  10. The generation of two-dimensional vortices by transverse oscillation of a soap film

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Afenchenko, V.O.; Ezersky, A.B.; Kiyashko, S.V.

    1998-02-01

    An experimental investigation of the dynamics of horizontal soap films stretched over circular or square boundaries undergoing periodic transverse oscillations at frequencies in the range 20{endash}200 Hz is reported. Concomitant with modes of transverse flexural oscillations, it was observed that two-dimensional vortices in the plane of the film are excited. The vortices may be either (i) large, scaling with the size of the cavity or (ii) small, localized at a wavelength or half-wavelength of the membrane modes. In the experiments a stable generation of one, two, {hor_ellipsis}, ten pairs of counter-rotating vortices were observed in finite regions of amplitude-frequency parametermore » space. The circulation strength of vortices in a given vortex pattern increases with increasing external forcing and with decreasing soap film thickness. A theoretical model based on the wave-boundary interaction of excited Marangoni waves reveals a vorticity generation mechanism active in vibrating soap films. This model shows that vorticity is generated throughout the entire liquid volume by viscous diffusion, and qualitatively reproduces many steady vortex patterns observed in the experiment. However, the model cannot explain the existence of the sometimes intense vortices observed far from the film boundary that do not appear to be generated by diffusive processes. {copyright} {ital 1998 American Institute of Physics.}« less

  11. Radiation effects and mitigation strategies for modern FPGAs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stettler, M. W.; Caffrey, M. P.; Graham, P. S.

    2004-01-01

    Field Programmable Gate Array devices have become the technology of choice in small volume modern instrumentation and control systems. These devices have always offered significant advantages in flexibility, and recent advances in fabrication have greatly increased logic capacity, substantially increasing the number of applications for this technology. Unfortunately, the increased density (and corresponding shrinkage of process geometry), has made these devices more susceptible to failure due to external radiation. This has been an issue for space based systems for some time, but is now becoming an issue for terrestrial systems in elevated radiation environments and commercial avionics as well. Characterizingmore » the failure modes of Xilinx FPGAs, and developing mitigation strategies is the subject of ongoing research by a consortium of academic, industrial, and governmental laboratories. This paper presents background information of radiation effects and failure modes, as well as current and future mitigation techniques. In particular, the availability of very large FPGA devices, complete with generous amounts of RAM and embedded processor(s), has led to the implementation of complete digital systems on a single device, bringing issues of system reliability and redundancy management to the chip level. Radiation effects on a single FPGA are increasingly likely to have system level consequences, and will need to be addressed in current and future designs.« less

  12. Research of Planetary Gear Fault Diagnosis Based on Permutation Entropy of CEEMDAN and ANFIS.

    PubMed

    Kuai, Moshen; Cheng, Gang; Pang, Yusong; Li, Yong

    2018-03-05

    For planetary gear has the characteristics of small volume, light weight and large transmission ratio, it is widely used in high speed and high power mechanical system. Poor working conditions result in frequent failures of planetary gear. A method is proposed for diagnosing faults in planetary gear based on permutation entropy of Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (CEEMDAN) Adaptive Neuro-fuzzy Inference System (ANFIS) in this paper. The original signal is decomposed into 6 intrinsic mode functions (IMF) and residual components by CEEMDAN. Since the IMF contains the main characteristic information of planetary gear faults, time complexity of IMFs are reflected by permutation entropies to quantify the fault features. The permutation entropies of each IMF component are defined as the input of ANFIS, and its parameters and membership functions are adaptively adjusted according to training samples. Finally, the fuzzy inference rules are determined, and the optimal ANFIS is obtained. The overall recognition rate of the test sample used for ANFIS is 90%, and the recognition rate of gear with one missing tooth is relatively high. The recognition rates of different fault gears based on the method can also achieve better results. Therefore, the proposed method can be applied to planetary gear fault diagnosis effectively.

  13. Molecular genetic and physical analysis of gas vesicles in buoyant enterobacteria

    PubMed Central

    Tashiro, Yosuke; Monson, Rita E.; Ramsay, Joshua P.

    2016-01-01

    Summary Different modes of bacterial taxis play important roles in environmental adaptation, survival, colonization and dissemination of disease. One mode of taxis is flotation due to the production of gas vesicles. Gas vesicles are proteinaceous intracellular organelles, permeable only to gas, that enable flotation in aquatic niches. Gene clusters for gas vesicle biosynthesis are partially conserved in various archaea, cyanobacteria, and some proteobacteria, such as the enterobacterium, S erratia sp. ATCC 39006 (S39006). Here we present the first systematic analysis of the genes required to produce gas vesicles in S39006, identifying how this differs from the archaeon H alobacterium salinarum. We define 11 proteins essential for gas vesicle production. Mutation of gvpN or gvpV produced small bicone gas vesicles, suggesting that the cognate proteins are involved in the morphogenetic assembly pathway from bicones to mature cylindrical forms. Using volumetric compression, gas vesicles were shown to comprise 17% of S39006 cells, whereas in E scherichia coli heterologously expressing the gas vesicle cluster in a deregulated environment, gas vesicles can occupy around half of cellular volume. Gas vesicle production in S39006 and E . coli was exploited to calculate the instantaneous turgor pressure within cultured bacterial cells; the first time this has been performed in either strain. PMID:26743231

  14. A dual-mode operation overmoded coaxial millimeter-wave generator with high power capacity and pure transverse electric and magnetic mode output

    NASA Astrophysics Data System (ADS)

    Bai, Zhen; Zhang, Jun; Zhong, Huihuang

    2016-04-01

    An overmoded coaxial millimeter-wave generator with high power capacity and pure transverse electric and magnetic (TEM) mode output is designed and presented, by using a kind of coaxial slow wave structure (SWS) with large transversal dimension and small distance between inner and outer conductors. The generator works in dual-mode operation mechanism. The electron beam synchronously interacts with 7π/8 mode of quasi-TEM, at the meanwhile exchanges energy with 3π/8 mode of TM01. The existence of TM01 mode, which is traveling wave, not only increases the beam-wave interaction efficiency but also improves the extraction efficiency. The large transversal dimension of coaxial SWS makes its power capacity higher than that of other reported millimeter-wave devices and the small distance between inner and outer conductors allows only two azimuthally symmetric modes to coexist. The converter after the SWS guarantees the mode purity of output power. Particle-in-cell simulation shows that when the diode voltage is 400 kV and beam current is 3.8 kA, the generation of microwave at 32.26 GHz with an output power of 611 MW and a conversion efficiency of 40% is obtained. The power percentage carried by TEM mode reaches 99.7% in the output power.

  15. Inflow/Outflow Conditions for Unsteady Aerodynamics and Aeroacoustics in Nonuniform Flow

    NASA Technical Reports Server (NTRS)

    Atassi, Oliver V.; Grady, Joseph E. (Technical Monitor)

    2003-01-01

    The effect of a nonuniform mean flow on the normal modes; the inflow/outflow nonreflecting boundary conditions; and the sound power are studied. The normal modes in an annular duct are computed using a spectral method in combination with a shooting method. The swirl causes force imbalance which couples the acoustic and vortical modes. The acoustic modes are distinguished from the vortical modes by their large pressure and small vorticity content. The mean swirl also produces a Doppler shift in frequency. This results in more counter-spinning modes cut-on at a given frequency than modes spinning with the swirl. Nonreflecting boundary conditions are formulated using the normal mode solutions. The inflow/outflow boundary conditions are implemented in a linearized Euler scheme and validated by computing the propagation of acoustic and vortical waves in a duct for a variety of swirling mean flows. Numerical results show that the evolution of the vortical disturbances is sensitive to the inflow conditions and the details of the wake excitations. All three components of the wake velocity must be considered to correctly compute the wake evolution and the blade upwash. For high frequencies, the acoustic-vortical mode coupling is weak and a conservation equation for the acoustic energy can be derived. Sound power calculations show significant mean flow swirl effects, but mode interference effects are small.

  16. A dual-mode operation overmoded coaxial millimeter-wave generator with high power capacity and pure transverse electric and magnetic mode output

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bai, Zhen; Zhang, Jun, E-mail: zhangjun@nudt.edu.cn; Zhong, Huihuang

    2016-04-15

    An overmoded coaxial millimeter-wave generator with high power capacity and pure transverse electric and magnetic (TEM) mode output is designed and presented, by using a kind of coaxial slow wave structure (SWS) with large transversal dimension and small distance between inner and outer conductors. The generator works in dual-mode operation mechanism. The electron beam synchronously interacts with 7π/8 mode of quasi-TEM, at the meanwhile exchanges energy with 3π/8 mode of TM{sub 01}. The existence of TM{sub 01} mode, which is traveling wave, not only increases the beam-wave interaction efficiency but also improves the extraction efficiency. The large transversal dimension ofmore » coaxial SWS makes its power capacity higher than that of other reported millimeter-wave devices and the small distance between inner and outer conductors allows only two azimuthally symmetric modes to coexist. The converter after the SWS guarantees the mode purity of output power. Particle-in-cell simulation shows that when the diode voltage is 400 kV and beam current is 3.8 kA, the generation of microwave at 32.26 GHz with an output power of 611 MW and a conversion efficiency of 40% is obtained. The power percentage carried by TEM mode reaches 99.7% in the output power.« less

  17. H-mode pedestal stability and ELMs in Alcator C-Mod

    NASA Astrophysics Data System (ADS)

    Mossessian, Dmitri

    2002-11-01

    For steady state H-mode operation, a relaxation mechanism is required to limit build-up of the edge gradient and impurity accumulation. The major relaxation mechanism seen on most of the existing tokamaks - large type I ELMs - drive high particle and energy fluxes that present a significant power load on the divertor plates. On Alcator C-Mod, however, type I ELMs are not observed. Instead, more benign mechanisms - EDA and small grassy ELMs - appear to drive enhanced particle transport at the edge of H-mode plasmas. Both have good energy confinement, no impurity accumulation, and are steady state. In EDA the edge relaxation mechanism is provided by a quasicoherent electromagnetic mode localized in the outer part of the pedestal. Non-linear gyrofluid and linear gyrokinetic simulations, as well as real geometry fluctuation modeling based on fluid equations show the presence of a coherent mode. Based on those results the observed mode is tentatively identified as resistive ballooning. At higher edge pressure gradient the mode is replaced by broadband fluctuations and small irregular ELMs are observed. Based on ideal MHD calculations that include effects of bootstrap current, these ELMs are identified as medium n coupled ideal peeling/ballooning modes. The stability threshold and modes structure of these modes are studied with recently developed linear MHD stability code ELITE and the results are compared with the observed dependence of the ELMs' character on pedestal parameters and plasma shape.

  18. Modifications of resting state networks in spinocerebellar ataxia type 2.

    PubMed

    Cocozza, Sirio; Saccà, Francesco; Cervo, Amedeo; Marsili, Angela; Russo, Cinzia Valeria; Giorgio, Sara Maria Delle Acque; De Michele, Giuseppe; Filla, Alessandro; Brunetti, Arturo; Quarantelli, Mario

    2015-09-01

    We aimed to investigate the integrity of the Resting State Networks in spinocerebellar ataxia type 2 (SCA2) and the correlations between the modification of these networks and clinical variables. Resting-state functional magnetic resonance imaging (RS-fMRI) data from 19 SCA2 patients and 29 healthy controls were analyzed using an independent component analysis and dual regression, controlling at voxel level for the effect of atrophy by co-varying for gray matter volume. Correlations between the resting state networks alterations and disease duration, age at onset, number of triplets, and clinical score were assessed by Spearman's coefficient, for each cluster which was significantly different in SCA2 patients compared with healthy controls. In SCA2 patients, disruption of the cerebellar components of all major resting state networks was present, with supratentorial involvement only for the default mode network. When controlling at voxel level for gray matter volume, the reduction in functional connectivity in supratentorial regions of the default mode network, and in cerebellar regions within the default mode, executive and right fronto-parietal networks, was still significant. No correlations with clinical variables were found for any of the investigated resting state networks. The SCA2 patients show significant alterations of the resting state networks, only partly explained by the atrophy. The default mode network is the only resting state network that shows also supratentorial changes, which appear unrelated to the cortical gray matter volume. Further studies are needed to assess the clinical significance of these changes. © 2015 International Parkinson and Movement Disorder Society.

  19. a Search for Nucleon Decay with Multiple Muon Decays

    NASA Astrophysics Data System (ADS)

    Phillips, Thomas James

    A search was made for nucleon decays which result in multiple delayed muon decays using the HPW (Harvard -Purdue-Wisconsin) water Cerenkov detector. The HPW detector consists of 680 metric tons of purified water instrumented with 704 five-inch photomultiplier tubes. The phototubes are situated on a volume array with a lattice spacing of approximately one meter, and the inside walls of the detector are lined with mirrors. This combination of mirrors and a volume array of phototubes gives the HPW detector a low trigger energy threshold and a high muon decay detection efficiency. The detector is surrounded by wire chambers to provide an active shield, and is located at a depth of 1500 meters-of-water-equivalent in the Silver King Mine in Park City, Utah. The entire HPW data set, consisting of 17.2 million events collec- ted during 282 live days between May 1983 and October 1984, was analyzed. No contained events with multiple muon decays were found in a 180 ton fiducial volume. This is consistent with the background rate from neutrino interactions, which is expected to be 0.7 (+OR-) 0.2 events. The calculated lower lifetime limit for the decay mode p (--->) (mu)('+)(mu)('+)(mu)('-) is: (tau)/B.R. = 1 x 10('31) years (90% C.L.). Limits are calculated for ten other proton decay modes and five bound neutron decay modes, most of which are around 4 x 10('30) years (90% C.L.). No previous studies have reported results from direct searches for eight of these modes.

  20. Application of failure mode and effects analysis (FMEA) to pretreatment phases in tomotherapy.

    PubMed

    Broggi, Sara; Cantone, Marie Claire; Chiara, Anna; Di Muzio, Nadia; Longobardi, Barbara; Mangili, Paola; Veronese, Ivan

    2013-09-06

    The aim of this paper was the application of the failure mode and effects analysis (FMEA) approach to assess the risks for patients undergoing radiotherapy treatments performed by means of a helical tomotherapy unit. FMEA was applied to the preplanning imaging, volume determination, and treatment planning stages of the tomotherapy process and consisted of three steps: 1) identification of the involved subprocesses; 2) identification and ranking of the potential failure modes, together with their causes and effects, using the risk probability number (RPN) scoring system; and 3) identification of additional safety measures to be proposed for process quality and safety improvement. RPN upper threshold for little concern of risk was set at 125. A total of 74 failure modes were identified: 38 in the stage of preplanning imaging and volume determination, and 36 in the stage of planning. The threshold of 125 for RPN was exceeded in four cases: one case only in the phase of preplanning imaging and volume determination, and three cases in the stage of planning. The most critical failures appeared related to (i) the wrong or missing definition and contouring of the overlapping regions, (ii) the wrong assignment of the overlap priority to each anatomical structure, (iii) the wrong choice of the computed tomography calibration curve for dose calculation, and (iv) the wrong (or not performed) choice of the number of fractions in the planning station. On the basis of these findings, in addition to the safety strategies already adopted in the clinical practice, novel solutions have been proposed for mitigating the risk of these failures and to increase patient safety.

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