[NO donors transform neuronal response to glutamate].

PubMed

D'iakonova, T L

1998-10-01

Electrophysiological experiments on three identified neurones were performed. Two NO donors, sodium nitroprusside (SNP) and sodium nitrite, as well as NO synthase inhibitor, were used. In each neurone, bath application of glutamate caused hyperpolarization and suppression of firing. Combined application of glutamate and SNP resulted in that the same cells responded to identical glutamate solutions with depolarization and excitation. Application of N-monomethyl-L-arginin (NMMA) arrested the glutamate-induced firing and depolarization. The findings suggest involvement of NO in the mechanism of transformation of glutamate-induced inhibition into excitation and a mediation of the latter by the N-methyl-D-aspartate-like receptors in the Helix brain.

Molecular and functional differences in voltage-activated sodium currents between GABA projection neurons and dopamine neurons in the substantia nigra

PubMed Central

Ding, Shengyuan; Wei, Wei

2011-01-01

GABA projection neurons (GABA neurons) in the substantia nigra pars reticulata (SNr) and dopamine projection neurons (DA neurons) in substantia nigra pars compacta (SNc) have strikingly different firing properties. SNc DA neurons fire low-frequency, long-duration spikes, whereas SNr GABA neurons fire high-frequency, short-duration spikes. Since voltage-activated sodium (NaV) channels are critical to spike generation, the different firing properties raise the possibility that, compared with DA neurons, NaV channels in SNr GABA neurons have higher density, faster kinetics, and less cumulative inactivation. Our quantitative RT-PCR analysis on immunohistochemically identified nigral neurons indicated that mRNAs for pore-forming NaV1.1 and NaV1.6 subunits and regulatory NaVβ1 and Navβ4 subunits are more abundant in SNr GABA neurons than SNc DA neurons. These α-subunits and β-subunits are key subunits for forming NaV channels conducting the transient NaV current (INaT), persistent Na current (INaP), and resurgent Na current (INaR). Nucleated patch-clamp recordings showed that INaT had a higher density, a steeper voltage-dependent activation, and a faster deactivation in SNr GABA neurons than in SNc DA neurons. INaT also recovered more quickly from inactivation and had less cumulative inactivation in SNr GABA neurons than in SNc DA neurons. Furthermore, compared with nigral DA neurons, SNr GABA neurons had a larger INaR and INaP. Blockade of INaP induced a larger hyperpolarization in SNr GABA neurons than in SNc DA neurons. Taken together, these results indicate that NaV channels expressed in fast-spiking SNr GABA neurons and slow-spiking SNc DA neurons are tailored to support their different spiking capabilities. PMID:21880943

The Sodium-Activated Potassium Channel Slack Is Required for Optimal Cognitive Flexibility in Mice

ERIC Educational Resources Information Center

Bausch, Anne E.; Dieter, Rebekka; Nann, Yvette; Hausmann, Mario; Meyerdierks, Nora; Kaczmarek, Leonard K.; Ruth, Peter; Lukowski, Robert

2015-01-01

"Kcnt1" encoded sodium-activated potassium channels (Slack channels) are highly expressed throughout the brain where they modulate the firing patterns and general excitability of many types of neurons. Increasing evidence suggests that Slack channels may be important for higher brain functions such as cognition and normal intellectual…

Activity of the anticonvulsant lacosamide in experimental and human epilepsy via selective effects on slow Na+ channel inactivation.

PubMed

Holtkamp, Dominik; Opitz, Thoralf; Niespodziany, Isabelle; Wolff, Christian; Beck, Heinz

2017-01-01

In human epilepsy, pharmacoresistance to antiepileptic drug therapy is a major problem affecting ~30% of patients with epilepsy. Many classical antiepileptic drugs target voltage-gated sodium channels, and their potent activity in inhibiting high-frequency firing has been attributed to their strong use-dependent blocking action. In chronic epilepsy, a loss of use-dependent block has emerged as a potential cellular mechanism of pharmacoresistance for anticonvulsants acting on voltage-gated sodium channels. The anticonvulsant drug lacosamide (LCM) also targets sodium channels, but has been shown to preferentially affect sodium channel slow inactivation processes, in contrast to most other anticonvulsants. We used whole-cell voltage clamp recordings in acutely isolated cells to investigate the effects of LCM on transient Na + currents. Furthermore, we used whole-cell current clamp recordings to assess effects on repetitive action potential firing in hippocampal slices. We show here that LCM exerts its effects primarily via shifting the slow inactivation voltage dependence to more hyperpolarized potentials in hippocampal dentate granule cells from control and epileptic rats, and from patients with epilepsy. It is important to note that this activity of LCM was maintained in chronic experimental and human epilepsy. Furthermore, we demonstrate that the efficacy of LCM in inhibiting high-frequency firing is undiminished in chronic experimental and human epilepsy. Taken together, these results show that LCM exhibits maintained efficacy in chronic epilepsy, in contrast to conventional use-dependent sodium channel blockers such as carbamazepine. They also establish that targeting slow inactivation may be a promising strategy for overcoming target mechanisms of pharmacoresistance. Wiley Periodicals, Inc. © 2016 International League Against Epilepsy.

Extinguishing agent for combustible metal fires

DOEpatents

Riley, John F.; Stauffer, Edgar Eugene

1976-10-12

A low chloride extinguishing agent for combustible metal fires comprising from substantially 75 to substantially 94 weight percent of sodium carbonate as the basic fire extinguishing material, from substantially 1 to substantially 5 weight percent of a water-repellent agent such as a metal stearate, from substantially 2 to substantially 10 weight percent of a flow promoting agent such as attapulgus clay, and from substantially 3 to substantially 15 weight percent of a polyamide resin as a crusting agent.

Analysis of the role of the low threshold currents IT and Ih in intrinsic delta oscillations of thalamocortical neurons.

PubMed

Amarillo, Yimy; Mato, Germán; Nadal, Marcela S

2015-01-01

Thalamocortical neurons are involved in the generation and maintenance of brain rhythms associated with global functional states. The repetitive burst firing of TC neurons at delta frequencies (1-4 Hz) has been linked to the oscillations recorded during deep sleep and during episodes of absence seizures. To get insight into the biophysical properties that are the basis for intrinsic delta oscillations in these neurons, we performed a bifurcation analysis of a minimal conductance-based thalamocortical neuron model including only the IT channel and the sodium and potassium leak channels. This analysis unveils the dynamics of repetitive burst firing of TC neurons, and describes how the interplay between the amplifying variable mT and the recovering variable hT of the calcium channel IT is sufficient to generate low threshold oscillations in the delta band. We also explored the role of the hyperpolarization activated cationic current Ih in this reduced model and determine that, albeit not required, Ih amplifies and stabilizes the oscillation.

High sodium coal-firing experiences at Basin Electric Power Cooperative's Leland Olds Station

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laning, V.R.; Bartle, M.L.

1982-12-01

This paper describes some of the efforts made at the Leland Olds Station to cope with the problems created from high sodium content coals. Such coals have historically presented superheater fouling problems for utilities; ash deposits from high sodium coals have a very high sintering strength and are very difficult to remove by conventional methods. It is reported that the addition of limestone in the pulverizer unit at Leland Olds and vermiculite ore in the cyclone unit has helped reduce the fouling characteristics of high sodium lignites in North Dakota at an affordable cost.

40 CFR Appendix O to Subpart G of... - Substitutes Listed in the September 27, 2006 Final Rule, Effective November 27, 2006

Code of Federal Regulations, 2012 CFR

2012-07-01

... latest edition of the NFPA 2001 Standard for Clean Agent Fire Extinguishing Systems, for whichever... Systems.Sodium bicarbonate release in all settings should be targeted so that increased blood pH level... to be in environments protected by Envirogel with sodium bicarbonate additive extinguishing systems...

40 CFR Appendix O to Subpart G of... - Substitutes Listed in the September 27, 2006 Final Rule, Effective November 27, 2006

Code of Federal Regulations, 2013 CFR

2013-07-01

... latest edition of the NFPA 2001 Standard for Clean Agent Fire Extinguishing Systems, for whichever... Systems.Sodium bicarbonate release in all settings should be targeted so that increased blood pH level... to be in environments protected by Envirogel with sodium bicarbonate additive extinguishing systems...

40 CFR Appendix O to Subpart G of... - Substitutes Listed in the September 27, 2006 Final Rule, Effective November 27, 2006

Code of Federal Regulations, 2011 CFR

2011-07-01

... latest edition of the NFPA 2001 Standard for Clean Agent Fire Extinguishing Systems, for whichever... Systems.Sodium bicarbonate release in all settings should be targeted so that increased blood pH level... to be in environments protected by Envirogel with sodium bicarbonate additive extinguishing systems...

40 CFR Appendix O to Subpart G of... - Substitutes Listed in the September 27, 2006 Final Rule, Effective November 27, 2006

Code of Federal Regulations, 2014 CFR

2014-07-01

... latest edition of the NFPA 2001 Standard for Clean Agent Fire Extinguishing Systems, for whichever... Systems.Sodium bicarbonate release in all settings should be targeted so that increased blood pH level... to be in environments protected by Envirogel with sodium bicarbonate additive extinguishing systems...

Toward a Mechanistic Source Term in Advanced Reactors: Characterization of Radionuclide Transport and Retention in a Sodium Cooled Fast Reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brunett, Acacia J.; Bucknor, Matthew; Grabaskas, David

A vital component of the U.S. reactor licensing process is an integrated safety analysis in which a source term representing the release of radionuclides during normal operation and accident sequences is analyzed. Historically, source term analyses have utilized bounding, deterministic assumptions regarding radionuclide release. However, advancements in technical capabilities and the knowledge state have enabled the development of more realistic and best-estimate retention and release models such that a mechanistic source term assessment can be expected to be a required component of future licensing of advanced reactors. Recently, as part of a Regulatory Technology Development Plan effort for sodium cooledmore » fast reactors (SFRs), Argonne National Laboratory has investigated the current state of knowledge of potential source terms in an SFR via an extensive review of previous domestic experiments, accidents, and operation. As part of this work, the significant sources and transport processes of radionuclides in an SFR have been identified and characterized. This effort examines all stages of release and source term evolution, beginning with release from the fuel pin and ending with retention in containment. Radionuclide sources considered in this effort include releases originating both in-vessel (e.g. in-core fuel, primary sodium, cover gas cleanup system, etc.) and ex-vessel (e.g. spent fuel storage, handling, and movement). Releases resulting from a primary sodium fire are also considered as a potential source. For each release group, dominant transport phenomena are identified and qualitatively discussed. The key product of this effort was the development of concise, inclusive diagrams that illustrate the release and retention mechanisms at a high level, where unique schematics have been developed for in-vessel, ex-vessel and sodium fire releases. This review effort has also found that despite the substantial range of phenomena affecting radionuclide release, the current state of knowledge is extensive, and in most areas may be sufficient. Several knowledge gaps were identified, such as uncertainty in release from molten fuel and availability of thermodynamic data for lanthanides and actinides in liquid sodium. However, the overall findings suggest that high retention rates can be expected within the fuel and primary sodium for all radionuclides other than noble gases.« less

Characterization of Firing Range Soil from Camp Edwards, MA, and the Efficacy of Acid and Alkaline Hydrolysis for the Remediation of M1 105mm M67 Propellant

DTIC Science & Technology

2013-06-01

method is intended for trace analysis of explosives and propellant residues by high performance liquid chromatography (HPLC) using an ultraviolet (UV...detector set at 254 nm. The HPLC used for this analysis was a Dionex Summit System with a UV detector equipped with Dionex E1 and E2 columns...Ca(OH)2) and sodium hydroxide (NaOH) were evaluated as sources of hydroxide ion for the alkaline hydrolysis of M1 propellant in soil from Camp

Effect of natural fiber types and sodium silicate coated on natural fiber mat/PLA composites: Tensile properties and rate of fire propagation

NASA Astrophysics Data System (ADS)

Thongpin, C.; Srimuk, J.; hipkam, N.; Wachirapong, P.

2015-07-01

In this study, 3 types of natural fibres, i.e. jute, sisal and abaca, were plain weaved to fibre mat. Before weaving, the fibres were treated with 5% NaOH to remove hemi cellulose and lignin. The weaving was performed by hand using square wooden block fit with nails for weaving using one and two types of natural fibres as weft and warp fibre to produce natural fibre mat. The fibre mat was also impregnated in sodium silicate solution extracted from rich husk ash. The pH of the solution was adjusted to pH 7 using H2SO4 before impregnation. After predetermined time, sodium silicate was gelled and deposited on the mat. The fabric mat and sodium silicate coated mat were then impregnated with PLA solution to produce prepreg. Dried pepreg was laminated with PLA sheet using compressing moulding machine to obtain natural fibre mat/PLA composite. The composite containing abaca aligned in longitudinal direction with respect to tension force enhanced Young's modulus more than 300%. Fibre mat composites with abaca aligned in longitudinal direction also showed tensile strength enhancement nearly 400% higher than neat PLA. After coating with sodium silicate, the tensile modulus of the composites was found slightly increased. The silicate coating was disadvantage on tensile strength of the composite due to the effect of sodium hydroxide solution that was used as solvent for silicate extraction from rice husk ash. However, sodium silicate could retard rate of fire propagation about 50%compare to neat PLA and about 10% reduction compared to fibre mat composites without sodium silicate coated fibre mat.

Solar thermal repowering systems integration. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dubberly, L. J.; Gormely, J. E.; McKenzie, A. W.

1979-08-01

This report is a solar repowering integration analysis which defines the balance-of-plant characteristics and costs associated with the solar thermal repowering of existing gas/oil-fired electric generating plants. Solar repowering interface requirements for water/steam and salt or sodium-cooled central receivers are defined for unit sizes ranging from 50 MWe non-reheat to 350 MWe reheat. Finally balance-of-plant cost estimates are presented for each of six combinations of plant type, receiver type and percent solar repowering.

Pharmacological characterization of ionic currents that regulate high-frequency spontaneous activity of electromotor neurons in the weakly electric fish, Apteronotus leptorhynchus.

PubMed

Smith, G Troy

2006-01-01

The neural circuit that controls the electric organ discharge (EOD) of the brown ghost knifefish (Apteronotus leptorhynchus) contains two spontaneous oscillators. Both pacemaker neurons in the medulla and electromotor neurons (EMNs) in the spinal cord fire spontaneously at frequencies of 500-1,000 Hz to control the EOD. These neurons continue to fire in vitro at frequencies that are highly correlated with in vivo EOD frequency. Previous studies used channel blocking drugs to pharmacologically characterize ionic currents that control high-frequency firing in pacemaker neurons. The goal of the present study was to use similar techniques to investigate ionic currents in EMNs, the other type of spontaneously active neuron in the electromotor circuit. As in pacemaker neurons, high-frequency firing of EMNs was regulated primarily by tetrodotoxin-sensitive sodium currents and by potassium currents that were sensitive to 4-aminopyridine and kappaA-conotoxin SIVA, but resistant to tetraethylammonium. EMNs, however, differed from pacemaker neurons in their sensitivity to some channel blocking drugs. Alpha-dendrotoxin, which blocks a subset of Kv1 potassium channels, increased firing rates in EMNs, but not pacemaker neurons; and the sodium channel blocker muO-conotoxin MrVIA, which reduced firing rates of pacemaker neurons, had no effect on EMNs. These results suggest that similar, but not identical, ionic currents regulate high-frequency firing in EMNs and pacemaker neurons. The differences in the ionic currents expressed in pacemaker neurons and EMNs might be related to differences in the morphology, connectivity, or function of these two cell types.

MELCOR/CONTAIN LMR Implementation Report. FY14 Progress

DOE Office of Scientific and Technical Information (OSTI.GOV)

Humphries, Larry L; Louie, David L.Y.

2014-10-01

This report describes the preliminary implementation of the sodium thermophysical properties and the design documentation for the sodium models of CONTAIN-LMR to be implemented into MELCOR 2.1. In the past year, the implementation included two separate sodium properties from two different sources. The first source is based on the previous work done by Idaho National Laboratory by modifying MELCOR to include liquid lithium equation of state as a working fluid to model the nuclear fusion safety research. To minimize the impact to MELCOR, the implementation of the fusion safety database (FSD) was done by utilizing the detection of the datamore » input file as a way to invoking the FSD. The FSD methodology has been adapted currently for this work, but it may subject modification as the project continues. The second source uses properties generated for the SIMMER code. Preliminary testing and results from this implementation of sodium properties are given. In this year, the design document for the CONTAIN-LMR sodium models, such as the two condensable option, sodium spray fire, and sodium pool fire is being developed. This design document is intended to serve as a guide for the MELCOR implementation. In addition, CONTAIN-LMR code used was based on the earlier version of CONTAIN code. Many physical models that were developed since this early version of CONTAIN may not be captured by the code. Although CONTAIN 2, which represents the latest development of CONTAIN, contains some sodium specific models, which are not complete, the utilizing CONTAIN 2 with all sodium models implemented from CONTAIN-LMR as a comparison code for MELCOR should be done. This implementation should be completed in early next year, while sodium models from CONTAIN-LMR are being integrated into MELCOR. For testing, CONTAIN decks have been developed for verification and validation use.« less

Measurements of alkali concentrations in an oxygen-natural gas-fired soda-lime-silica glass furnace

DOE Office of Scientific and Technical Information (OSTI.GOV)

S. G. Buckley; P. M. Walsh; D. w. Hahn

1999-10-18

Sodium species vaporized from melting batch and molten glass in tank furnaces are the principal agents of corrosion of superstructure refractory and main contributors to emissions of particulate matter from glass melting. The use of oxygen in place of air for combustion of natural gas reduces particulate emissions, but is thought to accelerate corrosion in some melting tanks. Methods for measuring sodium are under investigation as means for identifying the volatilization, transport, and deposition mechanisms and developing strategies for control. Three separate methods were used to measure the concentrations of sodium species at various locations in an oxygen-natural gas-fired soda-lime-silicamore » glass melting tank. Measurements were made inside the furnace using the absorption of visible light and in the flue duct using Laser-Induced Breakdown Spectroscopy (LIBS). Measurements in both the furnace and flue were also made by withdrawing and analyzing samples of the furnace gas.« less

Hunting for origins of migraine pain: cluster analysis of spontaneous and capsaicin-induced firing in meningeal trigeminal nerve fibers

PubMed Central

Zakharov, A.; Vitale, C.; Kilinc, E.; Koroleva, K.; Fayuk, D.; Shelukhina, I.; Naumenko, N.; Skorinkin, A.; Khazipov, R.; Giniatullin, R.

2015-01-01

Trigeminal nerves in meninges are implicated in generation of nociceptive firing underlying migraine pain. However, the neurochemical mechanisms of nociceptive firing in meningeal trigeminal nerves are little understood. In this study, using suction electrode recordings from peripheral branches of the trigeminal nerve in isolated rat meninges, we analyzed spontaneous and capsaicin-induced orthodromic spiking activity. In control, biphasic single spikes with variable amplitude and shapes were observed. Application of the transient receptor potential vanilloid 1 (TRPV1) agonist capsaicin to meninges dramatically increased firing whereas the amplitudes and shapes of spikes remained essentially unchanged. This effect was antagonized by the specific TRPV1 antagonist capsazepine. Using the clustering approach, several groups of uniform spikes (clusters) were identified. The clustering approach combined with capsaicin application allowed us to detect and to distinguish “responder” (65%) from “non-responder” clusters (35%). Notably, responders fired spikes at frequencies exceeding 10 Hz, high enough to provide postsynaptic temporal summation of excitation at brainstem and spinal cord level. Almost all spikes were suppressed by tetrodotoxin (TTX) suggesting an involvement of the TTX-sensitive sodium channels in nociceptive signaling at the peripheral branches of trigeminal neurons. Our analysis also identified transient (desensitizing) and long-lasting (slowly desensitizing) responses to the continuous application of capsaicin. Thus, the persistent activation of nociceptors in capsaicin-sensitive nerve fibers shown here may be involved in trigeminal pain signaling and plasticity along with the release of migraine-related neuropeptides from TRPV1 positive neurons. Furthermore, cluster analysis could be widely used to characterize the temporal and neurochemical profiles of other pain transducers likely implicated in migraine. PMID:26283923

Fire suppressing apparatus

DOEpatents

Buttrey, Kenneth E.

1982-11-02

Apparatus for smothering a liquid sodium fire comprises a pan, a perforated cover on the pan, and tubes depending from the cover and providing communication between the interior of the pan and the ambient atmosphere through the perforations in the cover. Liquid caught in the pan rises above the lower ends of the tubes and thus serves as a barrier which limits the amount of air entering the pan.

Development and testing of dry chemicals in advanced extinguishing systems for jet engine nacelle fires

NASA Technical Reports Server (NTRS)

Altman, R. L.; Ling, A. C. (Editor); Mayer, L. A.; Myronik, D. J.

1979-01-01

The effectiveness of dry chemical in extinguishing and delaying reignition of fires resulting from hydrocarbon fuel leaking onto heated surfaces such as can occur in jet engine nacelles is studied. The commercial fire extinguishant dry chemical tried are sodium and potassium bicarbonate, carbonate, chloride, carbamate (Monnex), metal halogen, and metal hydroxycarbonate compounds. Synthetic and preparative procedures for new materials developed, a new concept of fire control by dry chemical agents, descriptions of experiment assemblages to test dry chemical fire extinguishant efficiencies in controlling fuel fires initiated by hot surfaces, comparative testing data for more than 25 chemical systems in a 'static' assemblage with no air flow across the heated surface, and similar comparative data for more than ten compounds in a dynamic system with air flows up to 350 ft/sec are presented.

Analysis of the role of the low threshold currents IT and Ih in intrinsic delta oscillations of thalamocortical neurons

PubMed Central

Amarillo, Yimy; Mato, Germán; Nadal, Marcela S.

2015-01-01

Thalamocortical neurons are involved in the generation and maintenance of brain rhythms associated with global functional states. The repetitive burst firing of TC neurons at delta frequencies (1–4 Hz) has been linked to the oscillations recorded during deep sleep and during episodes of absence seizures. To get insight into the biophysical properties that are the basis for intrinsic delta oscillations in these neurons, we performed a bifurcation analysis of a minimal conductance-based thalamocortical neuron model including only the IT channel and the sodium and potassium leak channels. This analysis unveils the dynamics of repetitive burst firing of TC neurons, and describes how the interplay between the amplifying variable mT and the recovering variable hT of the calcium channel IT is sufficient to generate low threshold oscillations in the delta band. We also explored the role of the hyperpolarization activated cationic current Ih in this reduced model and determine that, albeit not required, Ih amplifies and stabilizes the oscillation. PMID:25999847

Cardiac Medications

MedlinePlus

... cholesterol from circulating in the blood. Watch an animation of how statins work. Reason for Medication Used ... Kindle Fire Popular Articles 1 Understanding Blood Pressure Readings 2 Sodium and Salt 3 Heart Attack Symptoms ...

Metaflumizone is a novel sodium channel blocker insecticide.

PubMed

Salgado, V L; Hayashi, J H

2007-12-15

Metaflumizone is a novel semicarbazone insecticide, derived chemically from the pyrazoline sodium channel blocker insecticides (SCBIs) discovered at Philips-Duphar in the early 1970s, but with greatly improved mammalian safety. This paper describes studies confirming that the insecticidal action of metaflumizone is due to the state-dependent blockage of sodium channels. Larvae of the moth Spodoptera eridania injected with metaflumizone became paralyzed, concomitant with blockage of all nerve activity. Furthermore, tonic firing of abdominal stretch receptor organs from Spodoptera frugiperda was blocked by metaflumizone applied in the bath, consistent with the block of voltage-dependent sodium channels. Studies on native sodium channels, in primary-cultured neurons isolated from the CNS of the larvae of the moth Manduca sexta and on Para/TipE sodium channels heterologously expressed in Xenopus (African clawed frog) oocytes, confirmed that metaflumizone blocks sodium channels by binding selectively to the slow-inactivated state, which is characteristic of the SCBIs. The results confirm that metaflumizone is a novel sodium channel blocker insecticide.

Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks

PubMed Central

Picton, Laurence D.; Nascimento, Filipe; Broadhead, Matthew J.; Sillar, Keith T.

2017-01-01

Ubiquitously expressed sodium pumps are best known for maintaining the ionic gradients and resting membrane potential required for generating action potentials. However, activity- and state-dependent changes in pump activity can also influence neuronal firing and regulate rhythmic network output. Here we demonstrate that changes in sodium pump activity regulate locomotor networks in the spinal cord of neonatal mice. The sodium pump inhibitor, ouabain, increased the frequency and decreased the amplitude of drug-induced locomotor bursting, effects that were dependent on the presence of the neuromodulator dopamine. Conversely, activating the pump with the sodium ionophore monensin decreased burst frequency. When more “natural” locomotor output was evoked using dorsal-root stimulation, ouabain increased burst frequency and extended locomotor episode duration, whereas monensin slowed and shortened episodes. Decreasing the time between dorsal-root stimulation, and therefore interepisode interval, also shortened and slowed activity, suggesting that pump activity encodes information about past network output and contributes to feedforward control of subsequent locomotor bouts. Using whole-cell patch-clamp recordings from spinal motoneurons and interneurons, we describe a long-duration (∼60 s), activity-dependent, TTX- and ouabain-sensitive, hyperpolarization (∼5 mV), which is mediated by spike-dependent increases in pump activity. The duration of this dynamic pump potential is enhanced by dopamine. Our results therefore reveal sodium pumps as dynamic regulators of mammalian spinal motor networks that can also be affected by neuromodulatory systems. Given the involvement of sodium pumps in movement disorders, such as amyotrophic lateral sclerosis and rapid-onset dystonia parkinsonism, knowledge of their contribution to motor network regulation also has considerable clinical importance. SIGNIFICANCE STATEMENT The sodium pump is ubiquitously expressed and responsible for at least half of total brain energy consumption. The pumps maintain ionic gradients and the resting membrane potential of neurons, but increasing evidence suggests that activity- and state-dependent changes in pump activity also influence neuronal firing. Here we demonstrate that changes in sodium pump activity regulate locomotor output in the spinal cord of neonatal mice. We describe a sodium pump-mediated afterhyperpolarization in spinal neurons, mediated by spike-dependent increases in pump activity, which is affected by dopamine. Understanding how sodium pumps contribute to network regulation and are targeted by neuromodulators, including dopamine, has clinical relevance due to the role of the sodium pump in diseases, including amyotrophic lateral sclerosis, parkinsonism, epilepsy, and hemiplegic migraine. PMID:28123025

pigk Mutation underlies macho behavior and affects Rohon-Beard cell excitability

PubMed Central

Carmean, V.; Yonkers, M. A.; Tellez, M. B.; Willer, J. R.; Willer, G. B.; Gregg, R. G.; Geisler, R.; Neuhauss, S. C.

2015-01-01

The study of touch-evoked behavior allows investigation of both the cells and circuits that generate a response to tactile stimulation. We investigate a touch-insensitive zebrafish mutant, macho (maco), previously shown to have reduced sodium current amplitude and lack of action potential firing in sensory neurons. In the genomes of mutant but not wild-type embryos, we identify a mutation in the pigk gene. The encoded protein, PigK, functions in attachment of glycophosphatidylinositol anchors to precursor proteins. In wild-type embryos, pigk mRNA is present at times when mutant embryos display behavioral phenotypes. Consistent with the predicted loss of function induced by the mutation, knock-down of PigK phenocopies maco touch insensitivity and leads to reduced sodium current (INa) amplitudes in sensory neurons. We further test whether the genetic defect in pigk underlies the maco phenotype by overexpressing wild-type pigk in mutant embryos. We find that ubiquitous expression of wild-type pigk rescues the touch response in maco mutants. In addition, for maco mutants, expression of wild-type pigk restricted to sensory neurons rescues sodium current amplitudes and action potential firing in sensory neurons. However, expression of wild-type pigk limited to sensory cells of mutant embryos does not allow rescue of the behavioral touch response. Our results demonstrate an essential role for pigk in generation of the touch response beyond that required for maintenance of proper INa density and action potential firing in sensory neurons. PMID:26133798

Impact of a long term fire retardant (Fire Trol 931) on the leaching of Na, Al, Fe, Mn, Cu and Si from a Mediterranean forest soil: a short-term, lab-scale study.

PubMed

Koufopoulou, Sofia; Michalopoulos, Charalampos; Tzamtzis, Nikolaos; Pappa, Athina

2014-06-01

Long term fire retardant (LTR) application for forest fire prevention purposes as well as wildland fires can result in chemical leaching from forest soils. Large quantities of sodium (Na), aluminium (Al), iron (Fe), manganese (Mn), copper (Cu) and silicon (Si) in leachates, mainly due to ammonium (one of the major LTR components) soil deposition, could affect the groundwater quality. The leaching of Na, Al, Fe, Mn, Cu and Si due to nitrogen based LTR application (Fire Trol 931) was studied at laboratory scale. The concentrations of Na(+), Al(3+), Fe(3+)/Fe(2+), Mn(2+), Cu(2+) and Si(4+) were measured in the resulting leachates from pots with forest soil and pine trees alone and in combination with fire. The leaching of Na, Fe and Si from treated pots was significantly greater than that from control pots. The leaching of Al, Mn and Cu was extremely low.

Autoradiographic localization of voltage-dependent sodium channels on the mouse neuromuscular junction using /sup 125/I-alpha scorpion toxin. I. Preferential labeling of glial cells on the presynaptic side

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boudier, J.L.; Jover, E.; Cau, P.

1988-05-01

Alpha-scorpion toxins bind specifically to the voltage-sensitive sodium channel in excitable membranes, and binding is potential-dependent. The radioiodinated toxin II from the scorpion Androctonus australis Hector (alpha ScTx) was used to localize voltage-sensitive sodium channels on the presynaptic side of mouse neuromuscular junctions (NMJ) by autoradiography using both light and electron microscopy. Silver grain localization was analyzed by the cross-fire method. At the light-microscopic level, grain density over NMJ appeared 6-8x higher than over nonjunctional muscle membrane. The specificity of labeling was verified by competition/displacement with an excess of native alpha ScTx. Labeling was also inhibited by incubation in depolarizingmore » conditions, showing its potential-dependence. At the electron-microscopic level, analysis showed that voltage-sensitive sodium channels labeled with alpha ScTx were almost exclusively localized on membranes, as expected. Due to washout after incubation, appreciable numbers of binding sites were not found on the postsynaptic membranes. However, on the presynaptic side, alpha ScTx-labeled voltage-sensitive sodium channels were localized on the membrane of non-myelin-forming Schwann cells covering NMJ. The axonal presynaptic membrane was not labeled. These results show that voltage-sensitive sodium channels are present on glial cells in vivo, as already demonstrated in vitro. It is proposed that these glial channels could be indirectly involved in the ionic homeostasis of the axonal environment.« less

Editor's highlight: Evaluation of a Microelectrode Array-based ...

EPA Pesticide Factsheets

Thousands of compounds in the environment have not been characterized for developmental neurotoxicity (DNT) hazard. To address this issue, methods to screen compounds rapidly for DNT hazard evaluation are necessary and are being developed for key neurodevelopmental processes. In order to develop an assay for network formation, the current study evaluated effects of a training set of chemicals on network ontogeny by measuring spontaneous electrical activity in neural networks grown on microelectrode arrays (MEA). Rat (0-24 h old) primary cortical cells were plated in 48 well MEA plates and exposed to six compounds: acetaminophen, bisindolylmaleimide-1 (Bis-1), domoic acid, mevastatin, sodium orthovanadate, and loperamide for a period of 12 days. Spontaneous network activity was recorded on days 2, 5, 7, 9, and 12 and viability was assessed using the Cell Titer Blue® assay on day 12. Network activity (e.g. mean firing rate (MFR), burst rate (BR), etc), increased between days 5 and 12. Random Forest analysis indicated that across all compounds and times, temporal correlation of firing patterns (r), MFR, BR, #of active electrodes and % of spikes in a burst were the most influential parameters in separating control from treated wells. All compounds except acetaminophen (≤ 30 µM) caused concentration-related effects on one or more of these parameters. Domoic acid and sodium orthovanadate altered several of these parameters in the absence of cytotoxicity. Although

The effects of ultraviolet-B radiation on the toxicity of fire-fighting chemicals

USGS Publications Warehouse

Calfee, R.D.; Little, E.E.

2003-01-01

The interactive effects of ultraviolet (UV) and fire-retardant chemicals were evaluated by exposing rainbow trout (Oncorhyncus mykiss) juveniles and tadpoles of southern leopard frogs (Rana sphenocephala) to six fire-retardant formulations with and without sodium ferrocyanide (yellow prussiate of soda [YPS]) and to YPS alone under three simulated UV light treatments. Yellow prussiate of soda is used as a corrosion inhibitor in some of the fire-retardant chemical formulations. The underwater UV intensities measured were about 2 to 10% of surface irradiance measured in various aquatic habitats and were within tolerance limits for the species tested. Mortality of trout and tadpoles exposed to Fire-Trol?? GTS-R, Fire-Trol 300-F, Fire-Trol LCA-R, and Fire-Trol LCA-F was significantly increased in the presence of UV radiation when YPS was present in the formulation. The boreal toad (Bufo boreas), listed as endangered by the state of Colorado (USA), and southern leopard frog were similar in their sensitivity to these chemicals. Photoenhancement of fire-retardant chemicals can occur in a range of aquatic habitats and may be of concern even when optical clarity of water is low; however, other habitat characteristics can also reduce fire retardant toxicity.

Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6.

PubMed

Shaaban, Khaled A; Saunders, Meredith A; Zhang, Yinan; Tran, Tuan; Elshahawi, Sherif I; Ponomareva, Larissa V; Wang, Xiachang; Zhang, Jianjun; Copley, Gregory C; Sunkara, Manjula; Kharel, Madan K; Morris, Andrew J; Hower, James C; Tremblay, Matthew S; Prendergast, Mark A; Thorson, Jon S

2017-01-27

The isolation and structure elucidation of six new bacterial metabolites [spoxazomicin D (2), oxachelins B and C (4, 5), and carboxamides 6-8] and 11 previously reported bacterial metabolites (1, 3, 9-12a, and 14-18) from Streptomyces sp. RM-14-6 is reported. Structures were elucidated on the basis of comprehensive 1D and 2D NMR and mass spectrometry data analysis, along with direct comparison to synthetic standards for 2, 11, and 12a,b. Complete 2D NMR assignments for the known metabolites lenoremycin (9) and lenoremycin sodium salt (10) were also provided for the first time. Comparative analysis also provided the basis for structural revision of several previously reported putative aziridine-containing compounds [exemplified by madurastatins A1, B1, C1 (also known as MBJ-0034), and MBJ-0035] as phenol-dihydrooxazoles. Bioactivity analysis [including antibacterial, antifungal, cancer cell line cytotoxicity, unfolded protein response (UPR) modulation, and EtOH damage neuroprotection] revealed 2 and 5 as potent neuroprotectives and lenoremycin (9) and its sodium salt (10) as potent UPR modulators, highlighting new functions for phenol-oxazolines/salicylates and polyether pharmacophores.

Voltage gated sodium channels as drug discovery targets

PubMed Central

Bagal, Sharan K; Marron, Brian E; Owen, Robert M; Storer, R Ian; Swain, Nigel A

2015-01-01

Voltage-gated sodium (NaV) channels are a family of transmembrane ion channel proteins. They function by forming a gated, water-filled pore to help establish and control cell membrane potential via control of the flow of ions between the intracellular and the extracellular environments. Blockade of NaVs has been successfully accomplished in the clinic to enable control of pathological firing patterns that occur in a diverse range of conditions such as chronic pain, epilepsy, and cardiac arrhythmias. First generation sodium channel modulator drugs, despite low inherent subtype selectivity, preferentially act on over-excited cells which reduces undesirable side effects in the clinic. However, the limited therapeutic indices observed with the first generation demanded a new generation of sodium channel inhibitors. The structure, function and the state of the art in sodium channel modulator drug discovery are discussed in this chapter. PMID:26646477

Unusual Voltage-Gated Sodium Currents as Targets for Pain.

PubMed

Barbosa, C; Cummins, T R

2016-01-01

Pain is a serious health problem that impacts the lives of many individuals. Hyperexcitability of peripheral sensory neurons contributes to both acute and chronic pain syndromes. Because voltage-gated sodium currents are crucial to the transmission of electrical signals in peripheral sensory neurons, the channels that underlie these currents are attractive targets for pain therapeutics. Sodium currents and channels in peripheral sensory neurons are complex. Multiple-channel isoforms contribute to the macroscopic currents in nociceptive sensory neurons. These different isoforms exhibit substantial variations in their kinetics and pharmacology. Furthermore, sodium current complexity is enhanced by an array of interacting proteins that can substantially modify the properties of voltage-gated sodium channels. Resurgent sodium currents, atypical currents that can enhance recovery from inactivation and neuronal firing, are increasingly being recognized as playing potentially important roles in sensory neuron hyperexcitability and pain sensations. Here we discuss unusual sodium channels and currents that have been identified in nociceptive sensory neurons, describe what is known about the molecular determinants of the complex sodium currents in these neurons. Finally, we provide an overview of therapeutic strategies to target voltage-gated sodium currents in nociceptive neurons. Copyright © 2016 Elsevier Inc. All rights reserved.

3D printed glass: surface finish and bulk properties as a function of the printing process

NASA Astrophysics Data System (ADS)

Klein, Susanne; Avery, Michael P.; Richardson, Robert; Bartlett, Paul; Frei, Regina; Simske, Steven

2015-03-01

It is impossible to print glass directly from a melt, layer by layer. Glass is not only very sensitive to temperature gradients between different layers but also to the cooling process. To achieve a glass state the melt, has to be cooled rapidly to avoid crystallization of the material and then annealed to remove cooling induced stress. In 3D-printing of glass the objects are shaped at room temperature and then fired. The material properties of the final objects are crucially dependent on the frit size of the glass powder used during shaping, the chemical formula of the binder and the firing procedure. For frit sizes below 250 μm, we seem to find a constant volume of pores of less than 5%. Decreasing frit size leads to an increase in the number of pores which then leads to an increase of opacity. The two different binders, 2- hydroxyethyl cellulose and carboxymethylcellulose sodium salt, generate very different porosities. The porosity of samples with 2-hydroxyethyl cellulose is similar to frit-only samples, whereas carboxymethylcellulose sodium salt creates a glass foam. The surface finish is determined by the material the glass comes into contact with during firing.

Cocaine disinhibits dopamine neurons in the ventral tegmental area via use-dependent blockade of GABA neuron voltage-sensitive sodium channels

PubMed Central

Steffensen, Scott C.; Taylor, Seth R.; Horton, Malia L.; Barber, Elise N.; Lyle, Laura T.; Stobbs, Sarah H.; Allison, David W.

2010-01-01

The aim of this study was to evaluate the effects of cocaine on γ-aminobutyric acid (GABA) and dopamine (DA) neurons in the ventral tegmental area (VTA). Utilizing single-unit recordings in vivo, microelectrophoretic administration of DA enhanced the firing rate of VTA GABA neurons via D2/D3 DA receptor activation. Lower doses of intravenous cocaine (0.25–0.5 mg/kg), or the DA transporter (DAT) blocker methamphetamine, enhanced VTA GABA neuron firing rate via D2/D3 receptor activation. Higher doses of cocaine (1.0–2.0 mg/kg) inhibited their firing rate, which was not sensitive to the D2/D3 antagonist eticlopride. The voltage-sensitive sodium channel (VSSC) blocker lidocaine inhibited the firing rate of VTA GABA neurons at all doses tested (0.25–2.0 mg/kg). Cocaine or lidocaine reduced VTA GABA neuron spike discharges induced by stimulation of the internal capsule (ICPSDs) at dose levels 0.25–2 mg/kg (IC50 1.2 mg/kg). There was no effect of DA or methamphetamine on ICPSDs, or of DA antagonists on cocaine inhibition of ICPSDs. In VTA GABA neurons in vitro, cocaine reduced (IC50 13 μm) current-evoked spikes and TTX-sensitive sodium currents in a use-dependent manner. In VTA DA neurons, cocaine reduced IPSCs (IC50 13 μm), increased IPSC paired-pulse facilitation and decreased spontaneous IPSC frequency, without affecting miniature IPSC frequency or amplitude. These findings suggest that cocaine acts on GABA neurons to reduce activity-dependent GABA release on DA neurons in the VTA, and that cocaine's use-dependent blockade of VTA GABA neuron VSSCs may synergize with its DAT inhibiting properties to enhance mesolimbic DA transmission implicated in cocaine reinforcement. PMID:19046384

MELCOR/CONTAIN LMR Implementation Report - FY16 Progress.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Louie, David; Humphries, Larry L.

2016-11-01

This report describes the progress of the CONTAIN - LMR sodium physics and chemistry models to be implemented in MELCOR 2.1. In the past three years , the implementation included the addition of sodium equations of state and sodium properties from two different sources. The first source is based on the previous work done by Idaho National Laboratory by modifying MELCOR to include liquid lithium equation of state as a working fluid to model the nuclear fusion safety research. The second source uses properties generated for the SIMMER code. The implemented modeling has been tested and results are reported inmore » this document. In addition, the CONTAIN - LMR code was derived from an early version of the CONTAIN code, and many physical models that were developed since this early version of CONTAIN are not available in this early code version. Therefore, CONTAIN 2 has been updated with the sodium models in CONTAIN - LMR as CONTAIN2 - LMR, which may be used to provide code-to-code comparison with CONTAIN - LMR and MELCOR when the sodium chemistry models from CONTAIN - LMR have been completed. Both the spray fire and pool fire chemistry routines from CONTAIN - LMR have been integrated into MELCOR 2.1, and debugging and testing are in progress. Because MELCOR only models the equation of state for liquid and gas phases of the coolant, a modeling gap still exists when dealing with experiments or accident conditions that take place when the ambient temperature is below the freezing point of sodium. An alternative method is under investigation to overcome this gap . We are no longer working on the separate branch from the main branch of MELCOR 2.1 since the major modeling of MELCOR 2.1 has been completed. At the current stage, the newly implemented sodium chemistry models will be a part of the main MELCOR release version (MELCOR 2.2). This report will discuss the accomplishments and issues relating to the implementation. Also, we will report on the planned completion of all remaining tasks in the upcoming FY2017, including the atmospheric chemistry model and sodium - concrete interaction model implementation .« less

Modelling soil sodium and potassium adsorption ratio (SPAR) in the immediate period after a grassland fire in Lithuania.

NASA Astrophysics Data System (ADS)

Pereira, Paulo; Cerda, Artemi; Misiūnė, Ieva

2015-04-01

The soil sodium and potassium adsorption ratio (SPAR) is an index that measures the amount of sodium and potassium adsorbed onto clay and organic matter surfaces, in relation to calcium and magnesium. Assess the potential of soil dispersion or flocculation, a process which has implication in soil hydraulic properties and erosion (Sarah, 2004). Depending on severity and the type of ash produced, fire can changes in the immediate period the soil nutrient status (Bodi et al. 2014). Ash releases onto soil surface a large amount of cations, due the high pH. Previous works showed that SPAR from ash slurries is higher than solutions produced from litter (Pereira et al., 2014a). Normally the spatial distribution of topsoil nutrients in the immediate period after the fire is very heterogeneous, due to the different impacts of fire. Thus it is important to identify the most accurate interpolation method in order to identify with better precision the impacts of fire on soil properties. The objective of this work is to test several interpolation methods. The study area is located in near Vilnius (Lithuania) at 54° 42' N, 25° 08 E, 158 masl. Four days after the fire it was designed a plot in a burned area with near Vilnius (Lithuania) at 54° 42' N, 25° 08 E, 158 masl. Twenty five samples were collected from the topsoil. The SPAR index was calculated according to the formula: (Na++K+)/(Ca2++Mg2+)1/2 (Sarah, 2004). Data followed the normal distribution, thus no transformation was required previous to data modelling. Several well know interpolation models were tested, as Inverse Distance to a Weight (IDW) with the power of 1, 2, 3 and 4, Radial Basis Functions (RBF), Inverse Multiquadratic (IMT), Multilog (MTG), Multiquadratic (MTQ), Natural Cubic Spline (NCS) and Thin Plate Spline (TPS) and Local Polynomial (LP) with the power of 1 and 2 and Ordinary Kriging. The best interpolator was the one which had the lowest Root Mean Square Error (RMSE) (Pereira et al., 2014b). The results showed that on average, SPAR index was 0.85, with a minimum of 0.18, a maximum of 1.55, a standard deviation of 0.38 and a coefficient of variation of 44.70%. No previous works were carried out on fire-affected soils, however comparing it to ash slurries obtained from previous works (Pereira et al., 2014a), the values were higher. Among all the interpolation methods tested, the most accurate was IDW 1 (RMSE=0.393), and the less precise NCS (RMSE=0.542). This shows that data distribution is highly variable in space, since IDW methods are better interpolators for data irregularly distributed. The high spatial variability distribution of SPAR is very likely to affect soil hydraulic properties and plant recuperation in the immediate period after the fire. More research is needed to identify the SPAR spatio-temporal impacts of fire on soil. Acknowledgments POSTFIRE (Soil quality, erosion control and plant cover recovery under different post-fire management scenarios, CGL2013-47862-C2-1-R), funded by the Spanish Ministry of Economy and Competitiveness; Fuegored; RECARE (Preventing and Remediating Degradation of Soils in Europe Through Land Care, FP7-ENV-2013-TWO STAGE), funded by the European Commission; and for the COST action ES1306 (Connecting European connectivity research). References Bodi, M., Martin, D.A., Santin, C., Balfour, V., Doerr, S.H., Pereira, P., Cerda, A., Mataix-Solera, J. (2014) Wildland fire ash: production, composition and eco-hyro-geomorphic effects. Earth-Science Reviews, 130, 103-127. Pereira, P., Úbeda, X., Martin, D., Mataix-Solera, J., Cerdà, A., Burguet, M. (2014a) Wildfire effects on extractable elements in ash from Pinus Pinaster forest in Portugal. Hydrological Processes, 28, 3681-3690. Pereira, P., Cerdà, A., Úbeda, X., Mataix-Solera, J. Arcenegui, V., Zavala, L. (2014) Modelling the impacts of wildfire on ash thickness in the immediate period after the fire. Land Degradation and Development. DOI: 10.1002/ldr.2195 Sarah, P. (2004) Soil sodium and potassium adsorption ratio along a Mediterranean-arid transect. Journal of Arid Environments, 59, 731-741.

Pilot scale-SO{sub 2} control by dry sodium bicarbonate injection and an electrostatic precipitator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pliat, M.J.; Wilder, J.M.

2007-10-15

A 500 actual cubic feet gas per minute (acfm) pilot-scale SO{sub 2} control study was undertaken to investigate flue gas desulfurization (FGD) by dry sodium sorbents in 400{sup o}F (204.5{sup o}C) flue gases emitted from a coal fired boiler with flue gas concentrations between 350 and 2500 ppm SO{sub 2}. Powdered sodium alkaline reagents were injected into the hot flue gas downstream of the air preheater and the spent reagents were collected using an electrostatic precipitator. Three different sorbents were used: processed sodium bicarbonate of two particle sizes; solution mined sodium bicarbonate, and processed sodium sesquicarbonate. SO{sub 2} concentrations weremore » measured upstream of the reagent injection, 25-ft (7.62 m) downstream of the injection point, and downstream of the electrostatic precipitator. SO{sub 2} collection efficiencies ranged from 40 to 80% using sodium bicarbonate stoichiometric ratios from 0.5 to 3.0. Much of the in-duct SO{sub 2} removal occurred during the first second of reagent reaction time, indicating that the sulfur dioxide-sodium reaction rates may be faster than have been measured for fixed bed measurements reported in the literature.« less

Mapping ash properties using principal components analysis

NASA Astrophysics Data System (ADS)

Pereira, Paulo; Brevik, Eric; Cerda, Artemi; Ubeda, Xavier; Novara, Agata; Francos, Marcos; Rodrigo-Comino, Jesus; Bogunovic, Igor; Khaledian, Yones

2017-04-01

In post-fire environments ash has important benefits for soils, such as protection and source of nutrients, crucial for vegetation recuperation (Jordan et al., 2016; Pereira et al., 2015a; 2016a,b). The thickness and distribution of ash are fundamental aspects for soil protection (Cerdà and Doerr, 2008; Pereira et al., 2015b) and the severity at which was produced is important for the type and amount of elements that is released in soil solution (Bodi et al., 2014). Ash is very mobile material, and it is important were it will be deposited. Until the first rainfalls are is very mobile. After it, bind in the soil surface and is harder to erode. Mapping ash properties in the immediate period after fire is complex, since it is constantly moving (Pereira et al., 2015b). However, is an important task, since according the amount and type of ash produced we can identify the degree of soil protection and the nutrients that will be dissolved. The objective of this work is to apply to map ash properties (CaCO3, pH, and select extractable elements) using a principal component analysis (PCA) in the immediate period after the fire. Four days after the fire we established a grid in a 9x27 m area and took ash samples every 3 meters for a total of 40 sampling points (Pereira et al., 2017). The PCA identified 5 different factors. Factor 1 identified high loadings in electrical conductivity, calcium, and magnesium and negative with aluminum and iron, while Factor 3 had high positive loadings in total phosphorous and silica. Factor 3 showed high positive loadings in sodium and potassium, factor 4 high negative loadings in CaCO3 and pH, and factor 5 high loadings in sodium and potassium. The experimental variograms of the extracted factors showed that the Gaussian model was the most precise to model factor 1, the linear to model factor 2 and the wave hole effect to model factor 3, 4 and 5. The maps produced confirm the patternd observed in the experimental variograms. Factor 1 and 2 maps showed high values in one area of the plot, while factors 3,4 and 5 had a cycled pattern. Using a PCA we resume the information of all dataset and we identify that ash properties have a different distribution in the studied area, that may be attributed to the different fire severities. References Bodi, M., Martin, D.A., Santin, C., Balfour, V., Doerr, S.H., Pereira, P., Cerda, A., Mataix-Solera, J. (2014) Wildland fire ash: production, composition and eco-hydro-geomorphic effects. Earth-Science Reviews, 130, 103-127. Cerdà A, Doerr SH. (2008) The effect of ash and needle cover on surface runoff and erosion in the immediate post-fire period. Catena 74, 256-263. Jordan, A., Zavala, L., Granjed, A.J., Gordillo-Rivero, A.J., Garcia-Moreno, J., Pereira, P., Barcenas-Moreno, G., Celis, R., Jimenez-Compan, E., Alanis, N. Wettability of ash conditions splash erosion and runoff rates in the postfire. Science of the Total Environment, 572, 1261-1268. Pereira, P. Cerdà, A., Úbeda, X., Mataix-Solera, J. Arcenegui, V., Zavala, L. (2015b) Modelling the impacts of wildfire on ash thickness in a short-term period. Land Degradation and Development, 26, 180-192. Pereira, P., Brevik, E., Cerda, A., Ubeda, X., Novara, A., Francos, M., Comino, R., Bogunovic, I., Khaledian, Y. Mapping ash extractable elements using principal component analysis In: Pereira, P., Brevik, E., Munoz-Rojas, M., Miller, B. (eds) Soil mapping and process modelling for sustainable land use management (Elsevier Publishing House) ISBN: 9780128052006 Pereira, P., Cerdà, A., Jordan, A., Zavala, L., Mataix-Solera, J., Arcenegui, V., Misiune, I., Keesstra, S., Novara, A. (2016) Vegetation recovery after a grassland fire in Lithuania. The effects of fire severity, slope position and aspect. Land Degradation and Development, 27, 1523-1534. Pereira, P., Rein, G., Martin, D. Editorial: Past and Present Post-Fire Environments. Science of the Total Environment, 573, 442-436. Pereira, P., Jordan, A., Cerdà, A., Martin, D. Editorial: The role of ash in fire-affected ecosystems. Catena, 135, 337-379.

Preliminary Design of Critical Function Monitoring System of PGSFR

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2015-07-01

A PGSFR (Prototype Gen-IV Sodium-cooled Fast Reactor) is under development at Korea Atomic Energy Research Institute. A critical function monitoring system of the PGSFR is preliminarily studied. The functions of CFMS are to display critical plant variables related to the safety of the plant during normal and accident conditions and guide the operators corrective actions to keep the plant in a safe condition and mitigate the consequences of accidents. The minimal critical functions of the PGSFR are composed of reactivity control, reactor core cooling, reactor coolant system integrity, primary heat transfer system(PHTS) heat removal, sodium water reaction mitigation, radiation controlmore » and containment conditions. The variables and alarm legs of each critical function of the PGSFR are as follows; - Reactivity control: The variables of reactivity control function are power range neutron flux instrumentation, intermediate range neutron flux instrumentation, source range neutron flux instrumentation, and control rod bottom contacts. The alarm leg to display the reactivity controls consists of status of control drop malfunction, high post trip power and thermal reactivity addition. - Reactor core cooling: The variables are PHTS sodium level, hot pool temperature of PHTS, subassembly exit temperature, cold pool temperature of the PHTS, PHTS pump current, and PHTS pump breaker status. The alarm leg consists of high core delta temperature, low sodium level of the PHTS, high subassembly exit temperature, and low PHTS pump load. - Reactor coolant system integrity: The variables are PHTS sodium level, cover gas pressure, and safeguard vessel sodium level. The alarm leg is composed of low sodium level of PHTS, high cover gas pressure and high sodium level of the safety guard vessel. - PHTS heat removal: The variables are PHTS sodium level, hot pool temperature of PHTS, core exit temperature, cold pool temperature of the PHTS, flow rate of passive residual heat removal system, flow rate of active residual heat removal system, and temperatures of air heat exchanger temperature of residual heat removal systems. The alarm legs are composed of two legs of a 'passive residual heat removal system not cooling' and 'active residual heat removal system not cooling'. - Sodium water reaction mitigation: The variables are intermediate heat transfer system(IHTS) pressure, pressure and temperature and level of sodium dump tank, the status of rupture disk, hydrogen concentration in IHTS and direct variable of sodium-water-reaction measure. The alarm leg consists of high IHTS pressure, the status of sodium water reaction mitigation system and the indication of direct measure. - Radiation control: The variables are radiation of PHTS, radiation of IHTS, and radiation of containment purge. The alarm leg is composed of high radiation of PHTS and IHTS, and containment purge system. - Containment condition: The variables are containment pressure, containment isolation status, and sodium fire. The alarm leg consists of high containment pressure, status of containment isolation and status of sodium fire. (authors)« less

Demonstration of a Retrofit Corrosion-Resistant Fire Hydrant Which Also Protects Against Deliberate Contamination of Critical Army Water Supplies

DTIC Science & Technology

2010-02-01

0.4 Sodium Cyanide 3.7 Fast acting, readily available Sodium Fluoroacetate 1.7 Tasteless, Colorless, Odorless Thallium Nitrate 3.4 Sarin 1 VX 0.15 L iq...TurbChlor TOC 1080 Aflatoxin Cyanide "VX" BUILDING STRONG®27 Beijing Olympics  GuardianBlue Systems selected for securing drinking water during the...Closed BUILDING STRONG®54 Features 304 Stainless Replacement Stem, Tensile Strength 80 Ksi E Coated Sleeve/Seat 11 ga, A-569 Hot Rolled Steel

Exterior Weathering Durability of Some Leach-Resistant Fire-Retardant Treatments for Wood Shingles: A Five-Year Report.

DTIC Science & Technology

1981-07-01

phos. Code 29 impregnation phonium chloride (90%. in water) 12.5.5%, sodium hydroxide 150%. in water) 2.16%, urea 2.06/%, a liquid melamine 4.35...1.08%.. dicyandlamide 4.54%. (9) impregnation formaldehyde (37%) 4.32%. phosphoric acid 7.06%. water $3.0%. UOFP_2 Pressure Treating solution: Urea 1.44...sodium hydroxide (500o in water) 0.8710, urea 0.800o. a liquid melamine 1.74°o, water 91.570 o. 29 Pressure impregnation Treating solution: Tetrakis

Atmospheric Dispersion of Sodium Aerosol due to a Sodium Leak in a Fast Breeder Reactor Complex

NASA Astrophysics Data System (ADS)

Punitha, G.; Sudha, A. Jasmin; Kasinathan, N.; Rajan, M.

Liquid sodium at high temperatures (470 K to 825 K) is used as the primary and secondary coolant in Liquid Metal cooled Fast Breeder Reactors (LMFBR). In the event of a postulated sodium leak in the Steam Generator Building (SGB) of a LMFBR, sodium readily combusts in the ambient air, especially at temperatures above 523 K. Intense sodium fire results and sodium oxide fumes are released as sodium aerosols. Sodium oxides are readily converted to sodium hydroxide in air due to the presence of moisture in it. Hence, sodium aerosols are invariably in the form of particulate sodium hydroxide. These aerosols damage not only the equipment and instruments due to their corrosive nature but also pose health hazard to humans. Hence, it is essential to estimate the concentration of sodium aerosols within the plant boundary for a sodium leak event. The Gaussian Plume Dispersion Model can obtain the atmospheric dispersion of sodium aerosols in an open terrain. However, this model does not give accurate results for dispersion in spaces close to the point of release and with buildings in between. The velocity field due to the wind is altered to a large extent by the intervening buildings and structures. Therefore, a detailed 3-D estimation of the velocity field and concentration has to be obtained through rigorous computational fluid dynamics (CFD) approach. PHOENICS code has been employed to determine concentration of sodium aerosols at various distances from the point of release. The dispersion studies have been carried out for the release of sodium aerosols at different elevations from the ground and for different wind directions.

Elucidation of pyrethroid and DDT receptor sites in the voltage-gated sodium channel.

PubMed

Zhorov, Boris S; Dong, Ke

2017-05-01

DDT and pyrethroid insecticides were among the earliest neurotoxins identified to act on voltage-gated sodium channels. In the 1960s, equipped with, at the time, new voltage-clamp techniques, Professor Narahashi and associates provided the initial evidence that DDT and allethrin (the first commercial pyrethroid insecticide) caused prolonged flow of sodium currents in lobster and squid giant axons. Over the next several decades, continued efforts by Prof. Narahashi's group as well as other laboratories led to a comprehensive understanding of the mechanism of action of DDT and pyrethroids on sodium channels. Fast forward to the 1990s, genetic, pharmacological and toxicological data all further confirmed voltage-gated sodium channels as the primary targets of DDT and pyrethroid insecticides. Modifications of the gating kinetics of sodium channels by these insecticides result in repetitive firing and/or membrane depolarization in the nervous system. This mini-review focuses on studies from Prof. Narahashi's pioneer work and more recent mutational and computational modeling analyses which collectively elucidated the elusive pyrethroid receptor sites as well as the molecular basis of differential sensitivities of insect and mammalian sodium channels to pyrethroids. Copyright © 2016 Elsevier B.V. All rights reserved.

Bias and uncertainty in the absorption emission measurement of atomic sodium density in the SSME exit plane

NASA Technical Reports Server (NTRS)

Bauman, Leslie E.

1990-01-01

The measurement of atomic sodium concentration in the TTB 019 firing of April 1990 is significant in that it represents the first measurement of density at the exit plane of the space shuttle main engine. The knowledge of the sodium density, combined with the certainty that the exit plane of the plume is optically thin at the sodium D-line wavelengths, provides essential information for evaluation of diagnostic techniques using sodium atoms, such as resonant Doppler velocimetry for temperature, pressure, and velocity through high resolution fluorescent lineshape analysis. The technique used for the sodium atom line transmission (SALT) measurements is that of resonant absorption emission using a hollow cathode lamp as the reference source. Through the use of two-dimensional kinetic (TDK) predictions of temperature and density for the flight engine case and radiative transfer calculations, this line-of-sight spectrally integrated transmission indicates a sodium atom concentration, i.e., mole fraction, of 0.91e-10. The subject of this paper is the assumptions and measurement uncertainties tied into the calculation. Because of the narrow shape of the source emission, the uncertainties in the absorption profile could introduce considerable bias in the measurement. The following were investigated: (1) the inclusion of hyperfine splitting of the D-lines in the calculation; (2) the use of the flight engine predictions of plume temperature and density versus those for the large throat engine; (3) the assumption of a Gaussian, i.e., Doppler, distribution for the source radiance with a temperature of 400 K; (4) the use of atomic collisional shift and width values for the work by Jongerius; and (5) a Doppler shift for a 7 degree outward velocity vector at the plume edge. Also included in the study was the bias introduced by an uncertainty in the measurement of the D1/D2 line ratio in the source.

Study to optimize gellant polymer-water systems for the control of hypergolic spills and fires

NASA Technical Reports Server (NTRS)

Jennings, R. R.; Macwilliams, D. C.; Foshee, W. C.; Katzer, M. F.

1973-01-01

A system of buffered gelled water was developed to prevent and control fires from small spills of nitrogen tetroxide-(N2O4)-Aerozine 50-hypergolic fuel. Laboratory studies on various alkalis, buffers, and seavengers for the fuel components are described. Chilling and sodium acetate-acetic acid buffer was found to be the best additives to the gelled water. Field tests and a delivery system (airborne) for the extinguishant are described. A short movie showing the field testing is available upon request.

Method of forming ceramic bricks

DOEpatents

Poeppel, R.B.; Claar, T.D.; Silkowski, P.

1987-04-22

A method for forming free standing ceramic bricks for use as tritium breeder material is disclosed. Aqueous solutions of sodium carbonate and potassium carbonate are mixed with an organic hydrocolloid dispersion and powdered lithium carbonate, spray dried, and ceramic bricks formed by molding in a die and firing.

Method of forming ceramic bricks

DOEpatents

Poeppel, Roger B.; Claar, Terry D.; Silkowski, Peter

1988-09-06

A method for forming free standing ceramic bricks for use as tritium breeder material is disclosed. Aqueous solutions of sodium carbonate and potassium carbonate are mixed with an organic hydrocolloid dispersion and powdered lithium carbonate, spray dried, and ceramic bricks formed by molding in a die and firing.

Method of forming ceramic bricks

DOEpatents

Poeppel, Roger B.; Claar, Terry D.; Silkowski, Peter

1988-01-01

A method for forming free standing ceramic bricks for use as tritium breeder material is disclosed. Aqueous solutions of sodium carbonate and potassium carbonate are mixed with an organic hydrocolloid dispersion and powdered lithium carbonate, spray dried, and ceramic bricks formed by molding in a die and firing.

Determination of gold in geologic materials by solvent extraction and atomic-absorption spectrometry

USGS Publications Warehouse

Huffman, Claude; Mensik, J.D.; Riley, L.B.

1967-01-01

The two methods presented for the determination of traces of gold in geologic materials are the cyanide atomic-absorption method and the fire-assay atomic-absorption method. In the cyanide method gold is leached with a sodium-cyanide solution. The monovalent gold is then oxidized to the trivalent state and concentrated by extracting into methyl isobutyl ketone prior to estimation by atomic absorption. In the fire-assay atomic-absorption method, the gold-silver bead obtained from fire assay is dissolved in nitric and hydrochloric acids. Gold is then concentrated by extracting into methyl isobutyl ketone prior to determination by atomic absorption. By either method concentrations as low as 50 parts per billion of gold can be determined in a 15-gram sample.

Fate of the chemical warfare agent O-ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (VX) on soil following accelerant-based fire and liquid decontamination.

PubMed

Gravett, M R; Hopkins, F B; Self, A J; Webb, A J; Timperley, C M; Riches, J R

2014-08-01

In the event of alleged use of organophosphorus nerve agents, all kinds of environmental samples can be received for analysis. These might include decontaminated and charred matter collected from the site of a suspected chemical attack. In other scenarios, such matter might be sampled to confirm the site of a chemical weapon test or clandestine laboratory decontaminated and burned to prevent discovery. To provide an analytical capability for these contingencies, we present a preliminary investigation of the effect of accelerant-based fire and liquid decontamination on soil contaminated with the nerve agent O-ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (VX). The objectives were (a) to determine if VX or its degradation products were detectable in soil after an accelerant-based fire promoted by aviation fuel, including following decontamination with Decontamination Solution 2 (DS2) or aqueous sodium hypochlorite, (b) to develop analytical methods to support forensic analysis of accelerant-soaked, decontaminated and charred soil and (c) to inform the design of future experiments of this type to improve analytical fidelity. Our results show for the first time that modern analytical techniques can be used to identify residual VX and its degradation products in contaminated soil after an accelerant-based fire and after chemical decontamination and then fire. Comparison of the gas chromatography-mass spectrometry (GC-MS) profiles of VX and its impurities/degradation products from contaminated burnt soil, and burnt soil spiked with VX, indicated that the fire resulted in the production of diethyl methylphosphonate and O,S-diethyl methylphosphonothiolate (by an unknown mechanism). Other products identified were indicative of chemical decontamination, and some of these provided evidence of the decontaminant used, for example, ethyl 2-methoxyethyl methylphosphonate and bis(2-methoxyethyl) methylphosphonate following decontamination with DS2. Sample preparation procedures and analytical methods suitable for investigating accelerant and decontaminant-soaked soil samples are presented. VX and its degradation products and/or impurities were detected under all the conditions studied, demonstrating that accelerant-based fire and liquid-based decontamination and then fire are unlikely to prevent the retrieval of evidence of chemical warfare agent (CWA) testing. This is the first published study of the effects of an accelerant-based fire on a CWA in environmental samples. The results will inform defence and security-based organisations worldwide and support the verification activities of the Organisation for the Prohibition of Chemical Weapons (OPCW), winner of the 2013 Nobel Peace Prize for its extensive efforts to eliminate chemical weapons.

Forage nutritive quality in the Serengeti ecosystem: The roles of fire and herbivory

USGS Publications Warehouse

Anderson, T.M.; Ritchie, M.E.; Mayemba, E.; Eby, S.; Grace, J.B.; McNaughton, S.J.

2007-01-01

Fire and herbivory are important determinants of nutrient availability in savanna ecosystems. Fire and herbivory effects on the nutritive quality of savanna vegetation can occur directly, independent of changes in the plant community, or indirectly, via effects on the plant community. Indirect effects can be further subdivided into those occurring because of changes in plant species composition or plant abundance (i.e., quality versus quantity). We studied relationships between fire, herbivory, rainfall, soil fertility, and leaf nitrogen (N), phosphorus (P), and sodium (Na) at 30 sites inside and outside of Serengeti National Park. Using structural equation modeling, we asked whether fire and herbivory influences were largely direct or indirect and how their signs and strengths differed within the context of natural savanna processes. Herbivory was associated with enhanced leaf N and P through changes in plant biomass and community composition. Fire was associated with reduced leaf nutrient concentrations through changes in plant community composition. Additionally, fire had direct positive effects on Na and nonlinear direct effects on P that partially mitigated the indirect negative effects. Key mechanisms by which fire reduced plant nutritive quality were through reductions of Na-rich grasses and increased abundance of Themeda triandra, which had below-average leaf nutrients. ?? 2007 by The University of Chicago. All rights reserved.

Short-term low-severity spring grassland fire impacts on soil extractable elements and soil ratios in Lithuania.

PubMed

Pereira, Paulo; Cerda, Artemi; Martin, Deborah; Úbeda, Xavier; Depellegrin, Daniel; Novara, Agata; Martínez-Murillo, Juan F; Brevik, Eric C; Menshov, Oleksandr; Comino, Jesus Rodrigo; Miesel, Jessica

2017-02-01

Spring grassland fires are common in boreal areas as a consequence of slash and burn agriculture used to remove dry grass to increase soil nutrient properties and crop production. However, few works have investigated fire impacts on these grassland ecosystems, especially in the immediate period after the fire. The objective of this work was to study the short-term impacts of a spring grassland fire in Lithuania. Four days after the fire we established a 400m 2 sampling grid within the burned area and in an adjacent unburned area with the same topographical, hydrological and pedological characteristics. We collected topsoil samples immediately after the fire (0months), 2, 5, 7 and 9months after the fire. We analysed soil pH, electrical conductivity (EC), major nutrients including calcium (Ca), magnesium (Mg), sodium (Na), and potassium (K), and the minor elements aluminium (Al), manganese (Mn), iron (Fe) and zinc (Zn). We also calculated the soil Na and K adsorption ratio (SPAR), Ca:Mg and Ca:Al. The results showed that this low-severity grassland fire significantly decreased soil pH, Al, and Mn but increased EC, Ca, Mg, and K,. There was no effect on Na, Fe, and Zn. There was a decrease of EC, Ca, Mg, and Na from 0months after the fire until 7months after the fire, with an increase during the last sampling period. Fire did not significantly affect SPAR. Ca:Mg decreased significantly immediately after the fire, but not to critical levels. Ca:Al increased after the fire, reducing the potential effects of Al on plants. Overall, fire impacts were mainly limited to the immediate period after the fire. Copyright © 2016 Elsevier B.V. All rights reserved.

Depolarized inactivation overcomes impaired activation to produce DRG neuron hyperexcitability in a Nav1.7 mutation in a patient with distal limb pain.

PubMed

Huang, Jianying; Yang, Yang; Dib-Hajj, Sulayman D; van Es, Michael; Zhao, Peng; Salomon, Jody; Drenth, Joost P H; Waxman, Stephen G

2014-09-10

Sodium channel Nav1.7, encoded by SCN9A, is expressed in DRG neurons and regulates their excitability. Genetic and functional studies have established a critical contribution of Nav1.7 to human pain disorders. We have now characterized a novel Nav1.7 mutation (R1279P) from a female human subject with distal limb pain, in which depolarized fast inactivation overrides impaired activation to produce hyperexcitability and spontaneous firing in DRG neurons. Whole-cell voltage-clamp recordings in human embryonic kidney (HEK) 293 cells demonstrated that R1279P significantly depolarizes steady-state fast-, slow-, and closed-state inactivation. It accelerates deactivation, decelerates inactivation, and facilitates repriming. The mutation increases ramp currents in response to slow depolarizations. Our voltage-clamp analysis showed that R1279P depolarizes channel activation, a change that was supported by our multistate structural modeling. Because this mutation confers both gain-of-function and loss-of-function attributes on the Nav1.7 channel, we tested the impact of R1279P expression on DRG neuron excitability. Current-clamp studies reveal that R1279P depolarizes resting membrane potential, decreases current threshold, and increases firing frequency of evoked action potentials within small DRG neurons. The populations of spontaneously firing and repetitively firing neurons were increased by expressing R1279P. These observations indicate that the dominant proexcitatory gating changes associated with this mutation, including depolarized steady-state fast-, slow-, and closed-state inactivation, faster repriming, and larger ramp currents, override the depolarizing shift of activation, to produce hyperexcitability and spontaneous firing of nociceptive neurons that underlie pain. Copyright © 2014 the authors 0270-6474/14/3412328-13$15.00/0.

Network-specific mechanisms may explain the paradoxical effects of carbamazepine and phenytoin.

PubMed

Thomas, Evan A; Petrou, Steven

2013-07-01

A common notion of the mechanism by which the antiepileptic drugs (AEDs) carbamazepine and phenytoin act is that they block sodium channels by binding preferentially to the inactivated state, thereby allowing normal neuronal firing while blocking ictal activity. However, these drugs have unpredictable efficacy and, in some cases, may exacerbate seizures. Previous studies have suggested that reducing sodium channel availability in the dentate gyrus (DG) paradoxically increases excitability. We used a biophysically detailed computer model of the DG to test the hypothesis that AEDs increase excitability by disproportionately reducing negative feedback mechanisms. We built a Markov model of sodium channel gating that reproduces responses to voltage clamp experiments in the presence of carbamazepine and phenytoin. We incorporated this validated Markov model into a biophysically realistic computer model of DG neurons and networks. Simulated drug concentrations were similar to those measured in cerebral spinal fluid in medicated patients. Single neuron models were stimulated with current injections, and networks were stimulated with perforant path synaptic input. In the network model, environmental effects were studied by introducing mossy fiber sprouting. As expected, drugs reduced sodium channel availability, which in turn reduced action potential amplitude. This had only a small effect on action potential (AP) firing rate during brief (100 msec) current injections. Paradoxically, long current injections (2,500 msec) increased AP firing rates. This was caused by reduced calcium entry and consequently reduced activation of calcium activated potassium channels. It is important to note that the main determinant of drug effect was resting membrane potential (RMP) and not action potential firing rate. Binding of phenytoin and carbamazepine is slow and, thus drug effects are largely determined by the long term state of the RMP. This paradoxical AP firing increase was dependent on the unusually large calcium-activated potassium conductances expressed by DG granule cells. This predicts that drug efficacy in a given network will depend on the precise makeup of conductances in the network. RMP is expected to vary with the level of activity in the network. We simulated the effects of drugs on single shot stimulus responses in networks with mossy fiber sprouting and varied the RMP in all neurons as a model for network activity. For an RMP of -50 mV, representing an active network, drugs had no effect, or in some cases, increased excitability. Drugs had an increasingly larger inhibitory effect on network responses as RMP decreased. An important prediction is that drugs will be unable to block ictal activity invading an active network. Our key findings are that drug effects depend on both intrinsic properties of the network and its behavioral state. This may explain the paradoxical and unpredictable effects of some AEDs on seizure control in some patients. Wiley Periodicals, Inc. © 2013 International League Against Epilepsy.

Vitex negundo induces an anticonvulsant effect by inhibiting voltage gated sodium channels in murine Neuro 2A cell line.

PubMed

Khan, Faisal; Saify, Zafar Saeed; Jamali, Khawar Saeed; Naz, Saima; Hassan, Sohail; Siddiqui, Sonia

2018-01-01

Vitex negundo (Vn) extract is famous for the treatment of neurological diseases such as migraine and epilepsy. These neurological diseases have been associated with abnormally increased influx of sodium ions into the neurons. Drugs that inhibit voltage gated sodium channels can be used as potent anti-epileptics. Till now, the effects of Vn on sodium channels have not been investigated. Therefore, we have investigated the effects of methalonic fraction of Vn extract in Murine Neuro 2A cell line. Cells were cultured in a defined medium with or without the Vn extract (100 μg/ml). Sodium currents were recorded using whole-cell patch clamp method. The data show that methanolic extract of Vn inhibited sodium currents in a dose dependent manner (IC50 =161μg/ml). Vn (100 μg/ml) shifted the steady-state inactivation curve to the left or towards the hyper polarization state. However, Vn did not show any effects on outward rectifying potassium currents. Moreover, Vn (100 μg/ml) significantly reduced the sustained repetitive (48±4.8%, P<0.01) firing from neonatal hippocampal neurons at 12 DIV. Hence, our data suggested that inhibition of sodium channels by Vn may exert pharmacological effects in reducing pain and convulsions.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The NOXSO Process uses a regenerable sorbent that removes SO{sub 2} and NO{sub x} simultaneously from flue gas. The sorbent is a stabilized {gamma}-alumina bed impregnated with sodium carbonate. The process was successfully tested at three different scales, equivalent to 0.017, 0.06 and 0.75 MW of flue gas generated from a coal-fired power plant. The Proof-of-Concept (POC) Test is the last test prior to a full-scale demonstration. A slip stream of flue gas equivalent to a 5 MW coal-fired power plant was used for the POC test. This paper summarizes the NOXSO POC plant and its test results.

Fire and explosion hazards related to the industrial use of potassium and sodium methoxides.

PubMed

Kwok, Q; Acheson, B; Turcotte, R; Janès, A; Marlair, G

2013-04-15

Sodium and potassium methoxides are used as an intermediary for a variety of products in several industrial applications. For example, current production of so called "1G-biodiesel" relies on processing a catalytic reaction called "transesterification". This reaction transforms lipid resources from biomass materials into fatty acid methyl and ethyl esters. 1-G biodiesel processes imply the use of methanol, caustic potash (KOH), and caustic soda (NaOH) for which the hazards are well characterized. The more recent introduction of the direct catalysts CH3OK and CH3ONa may potentially introduce new process hazards. From an examination of existing MSDSs concerning these products, it appears that no consensus currently exists on their intrinsic hazardous properties. Recently, l'Institut National de l'Environnement Industriel et des Risques (France) and the Canadian Explosives Research Laboratory (Canada) have embarked upon a joint effort to better characterize the thermal hazards associated with these catalysts. This work employs the more conventional tests for water reactivity as an ignition source, fire and dust explosion hazards, using isothermal nano-calorimetry, isothermal basket tests, the Fire Propagation Apparatus and a standard 20 L sphere, respectively. It was found that these chemicals can become self-reactive close to room temperature under specific conditions and can generate explosible dusts. Copyright © 2013 Crown. Published by Elsevier B.V. All rights reserved.

Highly Flexible Superhydrophobic and Fire-Resistant Layered Inorganic Paper.

PubMed

Chen, Fei-Fei; Zhu, Ying-Jie; Xiong, Zhi-Chao; Sun, Tuan-Wei; Shen, Yue-Qin

2016-12-21

Traditional paper made from plant cellulose fibers is easily destroyed by either liquid or fire. In addition, the paper making industry consumes a large amount of natural trees and thus causes serious environmental problems including excessive deforestation and pollution. In consideration of the intrinsic flammability of organics and minimizing the effects on the environment and creatures, biocompatible ultralong hydroxyapatite nanowires are an ideal building material for inorganic fire-resistant paper. Herein, a new kind of free-standing, highly flexible, superhydrophobic, and fire-resistant layered inorganic paper has been successfully prepared using ultralong hydroxyapatite nanowires as building blocks after the surface modification with sodium oleate. During the vacuum filtration, ultralong hydroxyapatite nanowires assemble into self-roughened setalike microfibers, avoiding the tedious fabrication process to construct the hierarchical structure; the self-roughened microfibers further form the inorganic paper with a nacrelike layered structure. We have demonstrated that the layered structure can significantly improve the resistance to mechanical destruction of the as-prepared superhydrophobic paper. The as-prepared superhydrophobic and fire-resistant inorganic paper shows excellent nonflammability, liquid repellency to various commercial drinks, high thermal stability, and self-cleaning property. Moreover, we have explored the potential applications of the superhydrophobic and fire-resistant inorganic paper as a highly effective adsorbent for oil/water separation, fire-shielding protector, and writing paper.

Large-scale, thick, self-assembled, nacre-mimetic brick-walls as fire barrier coatings on textiles

NASA Astrophysics Data System (ADS)

Das, Paramita; Thomas, Helga; Moeller, Martin; Walther, Andreas

2017-01-01

Highly loaded polymer/clay nanocomposites with layered structures are emerging as robust fire retardant surface coatings. However, time-intensive sequential deposition processes, e.g. layer-by-layer strategies, hinders obtaining large coating thicknesses and complicates an implementation into existing technologies. Here, we demonstrate a single-step, water-borne approach to prepare thick, self-assembling, hybrid fire barrier coatings of sodium carboxymethyl cellulose (CMC)/montmorillonite (MTM) with well-defined, bioinspired brick-wall nanostructure, and showcase their application on textile. The coating thickness on the textile is tailored using different concentrations of CMC/MTM (1-5 wt%) in the coating bath. While lower concentrations impart conformal coatings of fibers, thicker continuous coatings are obtained on the textile surface from highest concentration. Comprehensive fire barrier and fire retardancy tests elucidate the increasing fire barrier and retardancy properties with increasing coating thickness. The materials are free of halogen and heavy metal atoms, and are sourced from sustainable and partly even renewable building blocks. We further introduce an amphiphobic surface modification on the coating to impart oil and water repellency, as well as self-cleaning features. Hence, our study presents a generic, environmentally friendly, scalable, and one-pot coating approach that can be introduced into existing technologies to prepare bioinspired, thick, fire barrier nanocomposite coatings on diverse surfaces.

Intrinsic and integrative properties of substantia nigra pars reticulata neurons

PubMed Central

Zhou, Fu-Ming; Lee, Christian R.

2011-01-01

The GABA projection neurons of the substantia nigra pars reticulata (SNr) are output neurons for the basal ganglia and thus critical for movement control. Their most striking neurophysiological feature is sustained, spontaneous high frequency spike firing. A fundamental question is: what are the key ion channels supporting the remarkable firing capability in these neurons? Recent studies indicate that these neurons express tonically active TRPC3 channels that conduct a Na-dependent inward current even at hyperpolarized membrane potentials. When the membrane potential reaches −60 mV, a voltage-gated persistent sodium current (INaP) starts to activate, further depolarizing the membrane potential. At or slightly below −50 mV, the large transient voltage-activated sodium current (INaT) starts to activate and eventually triggers the rapid rising phase of action potentials. SNr GABA neurons have a higher density of (INaT), contributing to the faster rise and larger amplitude of action potentials, compared with the slow-spiking dopamine neurons. INaT also recovers from inactivation more quickly in SNr GABA neurons than in nigral dopamine neurons. In SNr GABA neurons, the rising phase of the action potential triggers the activation of high-threshold, inactivation-resistant Kv3-like channels that can rapidly repolarize the membrane. These intrinsic ion channels provide SNr GABA neurons with the ability to fire spontaneous and sustained high frequency spikes. Additionally, robust GABA inputs from direct pathway medium spiny neurons in the striatum and GABA neurons in the globus pallidus may inhibit and silence SNr GABA neurons, whereas glutamate synaptic input from the subthalamic nucleus may induce burst firing in SNr GABA neurons. Thus, afferent GABA and glutamate synaptic inputs sculpt the tonic high frequency firing of SNr GABA neurons and the consequent inhibition of their targets into an integrated motor control signal that is further fine-tuned by neuromodulators including dopamine, serotonin, endocannabinoids, and H2O2. PMID:21839148

Fire-Resistant Composites

NASA Technical Reports Server (NTRS)

Kourtides, D. A.; Parker, J. A.

1983-01-01

Resin blend produces high-char-yield, low-smoke composites. Diglycidyl Ether of Bis-(4-Hydroxyphenyl)-Fluorene is prepared by reacting epichlorohydrin and sodium hydroxide with 9,9-bis(hydroxyphenyl) fluorene. End of reaction determined by gas or liquid chromatography, mass spectroscopy or infrared techniques. Used to manufacture printed circuit boards and panels for buildings, ships and aircraft.

Demonstration Extension: Copper-to-Silver-to-Gold Penny Demonstration

ERIC Educational Resources Information Center

Vitz, Ed

2008-01-01

This demonstration, if done in the original way, can lead to fires in waste containers (sometimes in the middle of the night after the experiment has been conducted), because pyrophoric zinc is generated by suspending powdered zinc in hot sodium hydroxide. This is avoided by using hot ZnSO[subscript 4].

Mechanisms for Selective Single-Cell Reactivation during Offline Sharp-Wave Ripples and Their Distortion by Fast Ripples.

PubMed

Valero, Manuel; Averkin, Robert G; Fernandez-Lamo, Ivan; Aguilar, Juan; Lopez-Pigozzi, Diego; Brotons-Mas, Jorge R; Cid, Elena; Tamas, Gabor; Menendez de la Prida, Liset

2017-06-21

Memory traces are reactivated selectively during sharp-wave ripples. The mechanisms of selective reactivation, and how degraded reactivation affects memory, are poorly understood. We evaluated hippocampal single-cell activity during physiological and pathological sharp-wave ripples using juxtacellular and intracellular recordings in normal and epileptic rats with different memory abilities. CA1 pyramidal cells participate selectively during physiological events but fired together during epileptic fast ripples. We found that firing selectivity was dominated by an event- and cell-specific synaptic drive, modulated in single cells by changes in the excitatory/inhibitory ratio measured intracellularly. This mechanism collapses during pathological fast ripples to exacerbate and randomize neuronal firing. Acute administration of a use- and cell-type-dependent sodium channel blocker reduced neuronal collapse and randomness and improved recall in epileptic rats. We propose that cell-specific synaptic inputs govern firing selectivity of CA1 pyramidal cells during sharp-wave ripples. Copyright © 2017 Elsevier Inc. All rights reserved.

Neutron activation determination of iridium, gold, platinum, and silver in geologic samples

USGS Publications Warehouse

Millard, H.T.

1987-01-01

Low-level methods for the determination of iridium and other noble metals have become increasingly important in recent years due to interest in locating abundance anomalies associated with the Cretaceous and Tertiary (K-T) boundary. Typical iridium anomalies are in the range of 1 to 100 ??g/kg (ppb). Thus methods with detection limits near 0.1 ??g/kg should be adequate to detect K-T boundary anomalies. Radiochemical neutron activation analysis methods continue to be required although instrumental neutron activation analysis techniques employing elaborate gamma-counters are under development. In the procedure developed in this study samples irradiated in the epithermal neutron facility of the U. S. Geological Survey TRIGA Reactor (Denver, Colorado) are treated with a mini-fire assay technique. The iridium, gold, and silver are collected in a 1-gram metallic lead button. Primary contaminants at this stage are arsenic and antimony. These can be removed by heating the button with a mixture of sodium perioxide and sodium hydroxide. The resulting 0.2-gram lead bead is counted in a Compton suppression spectrometer. Carrier yields are determined by reirradiation of the lead beads. This procedure has been applied to the U.S.G.S. Standard Rock PCC-1 and samples from K-T boundary sites in the Western Interior of North America. ?? 1987 Akade??miai Kiado??.

Inhibition of tetrodotoxin-resistant sodium current in dorsal root ganglia neurons mediated by D1/D5 dopamine receptors

PubMed Central

2013-01-01

Background Dopaminergic fibers originating from area A11 of the hypothalamus project to different levels of the spinal cord and represent the major source of dopamine. In addition, tyrosine hydroxylase, the rate-limiting enzyme for the synthesis of catecholamines, is expressed in 8-10% of dorsal root ganglia (DRG) neurons, suggesting that dopamine may be released in the dorsal root ganglia. Dopamine has been shown to modulate calcium current in DRG neurons, but the effects of dopamine on sodium current and on the firing properties of small DRG neurons are poorly understood. Results The effects of dopamine and dopamine receptor agonists were tested on the tetrodotoxin-resistant (TTX-R) sodium current recorded from acutely dissociated small (diameter ≤ 25 μm) DRG neurons. Dopamine (20 μM) and SKF 81297 (10 μM) caused inhibition of TTX-R sodium current in small DRG neurons by 23% and 37%, respectively. In contrast, quinpirole (20 μM) had no effects on the TTX-R sodium current. Inhibition by SKF 81297 of the TTX-R sodium current was not affected when the protein kinase A (PKA) activity was blocked with the PKA inhibitory peptide (6–22), but was greatly reduced when the protein kinase C (PKC) activity was blocked with the PKC inhibitory peptide (19–36), suggesting that activation of D1/D5 dopamine receptors is linked to PKC activity. Expression of D1and D5 dopamine receptors in small DRG neurons, but not D2 dopamine receptors, was confirmed by Western blotting and immunofluorescence analysis. In current clamp experiments, the number of action potentials elicited in small DRG neurons by current injection was reduced by ~ 30% by SKF 81297. Conclusions We conclude that activation of D1/D5 dopamine receptors inhibits TTX-R sodium current in unmyelinated nociceptive neurons and dampens their intrinsic excitability by reducing the number of action potentials in response to stimulus. Increasing or decreasing levels of dopamine in the dorsal root ganglia may serve to adjust the sensitivity of nociceptors to noxious stimuli. PMID:24283218

Large-scale, thick, self-assembled, nacre-mimetic brick-walls as fire barrier coatings on textiles

PubMed Central

Das, Paramita; Thomas, Helga; Moeller, Martin; Walther, Andreas

2017-01-01

Highly loaded polymer/clay nanocomposites with layered structures are emerging as robust fire retardant surface coatings. However, time-intensive sequential deposition processes, e.g. layer-by-layer strategies, hinders obtaining large coating thicknesses and complicates an implementation into existing technologies. Here, we demonstrate a single-step, water-borne approach to prepare thick, self-assembling, hybrid fire barrier coatings of sodium carboxymethyl cellulose (CMC)/montmorillonite (MTM) with well-defined, bioinspired brick-wall nanostructure, and showcase their application on textile. The coating thickness on the textile is tailored using different concentrations of CMC/MTM (1–5 wt%) in the coating bath. While lower concentrations impart conformal coatings of fibers, thicker continuous coatings are obtained on the textile surface from highest concentration. Comprehensive fire barrier and fire retardancy tests elucidate the increasing fire barrier and retardancy properties with increasing coating thickness. The materials are free of halogen and heavy metal atoms, and are sourced from sustainable and partly even renewable building blocks. We further introduce an amphiphobic surface modification on the coating to impart oil and water repellency, as well as self-cleaning features. Hence, our study presents a generic, environmentally friendly, scalable, and one-pot coating approach that can be introduced into existing technologies to prepare bioinspired, thick, fire barrier nanocomposite coatings on diverse surfaces. PMID:28054589

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romander, C.M.

The potential hazard of HCDA-generated missiles is analyzed, and the current status of the potential hazards of sodium fires is summarized. Simple analyses are performed to determine lower bounds on the HCDA energetics required to generate missiles that could reach the secondary containment structure of a 1000-MWe LMFBR. The potential missiles considered include the vessel head, components mounted on the head, and conrol rods.

Diazepam reduces excitability of amygdala and further influences auditory cortex following sodium salicylate treatment in rats.

PubMed

Song, Yu; Liu, Junxiu; Ma, Furong; Mao, Lanqun

2016-12-01

Diazepam can reduce the excitability of lateral amygdala and eventually suppress the excitability of the auditory cortex in rats following salicylate treatment, indicating the regulating effect of lateral amygdala to the auditory cortex in the tinnitus procedure. To study the spontaneous firing rates (SFR) of the auditory cortex and lateral amygdala regulated by diazepam in the tinnitus rat model induced by sodium salicylate. This study first created a tinnitus rat modal induced by sodium salicylate, and recorded SFR of both auditory cortex and lateral amygdala. Then diazepam was intraperitoneally injected and the SFR changes of lateral amygdala recorded. Finally, diazepam was microinjected on lateral amygdala and the SFR changes of the auditory cortex recorded. Both SFRs of the auditory cortex and lateral amygdala increased after salicylate treatment. SFR of lateral amygdala decreased after intraperitoneal injection of diazepam. Microinjecting diazepam to lateral amygdala decreased SFR of the auditory cortex ipsilaterally and contralaterally.

Acute toxicity of fire-control chemicals, nitrogenous chemicals, and surfactants to rainbow trout

USGS Publications Warehouse

Buhl, Kevin J.; Hamilton, Steven J.

2000-01-01

Laboratory studies were conducted to determine the acute toxicity of three ammonia-based fire retardants (Fire-Trol LCA-F, Fire-Trol LCM-R, and Phos-Chek 259F), five surfactant-based fire-suppressant foams (FireFoam 103B, FireFoam 104, Fire Quench, ForExpan S, and Pyrocap B-136), three nitrogenous chemicals (ammonia, nitrate, and nitrite), and two anionic surfactants (linear alkylbenzene sulfonate [LAS] and sodium dodecyl sulfate [SDS]) to juvenile rainbow trout Oncorhynchus mykiss in soft water. The descending rank order of toxicity (96-h concentration lethal to 50% of test organisms [96-h LC50]) for the fire retardants was as follows: Phos-Chek 259F (168 mg/L) > Fire-Trol LCA-F (942 mg/L) = Fire-Trol LCM-R (1,141 mg/L). The descending rank order of toxicity for the foams was as follows: FireFoam 103B (12.2 mg/L) = FireFoam 104 (13.0 mg/L) > ForExpan S (21.8 mg/L) > Fire Quench (39.0 mg/L) > Pyrocap B-136 [156 mg/L). Except for Pyrocap B-136, the foams were more toxic than the fire retardants. Un-ionized ammonia (NH3; 0.125 mg/L as N) was about six times more toxic than nitrite (0.79 mg/L NO2-N) and about 13,300 times more toxic than nitrate (1,658 mg/L NO3-N). Linear alkylbenzene sulfonate (5.0 mg/L) was about five times more toxic than SDS (24.9 mg/L). Estimated total ammonia and NH3 concentrations at the 96-h LC50s of the fire retardants indicated that ammonia was the primary toxic component in these formulations. Based on estimated anionic surfactant concentrations at the 96-h LC50s of the foams and reference surfactants, LAS was intermediate in toxicity and SDS was less toxic to rainbow trout when compared with the foams. Comparisons of recommended application concentrations to the test results indicate that accidental inputs of these chemicals into streams require substantial dilutions (100-1,750-fold to reach concentrations nonlethal to rainbow trout.

Sol-gel synthesis and characterizations of crystalline NaGd(WO4)2 powder for anisotropic transparent ceramic laser application

NASA Astrophysics Data System (ADS)

Durairajan, A.; Thangaraju, D.; Balaji, D.; Moorthy Babu, S.

2013-02-01

NaGd(WO4)2 powders were synthesized at different pH (3.5, 4.5, 5.5, 6.5 and 7.5) values by conventional Pechini method. Sodium and gadolinium nitrate salts and ammonium paratungstate are used as starting precursors. Metal cations were chelated by citric acid and individual citrates were bound together with ethylene glycol. Synthesized gel was analyzed using differential thermal analysis (DTA), thermo gravimetric (TG) and FT-IR spectroscopy to understand the degradation of gel and formation of metal citrates. Calcined powders (250, 600, 700 and 800 °C) were characterized by powder XRD, FT-IR, Raman and FE-SEM analysis. The temperature dependent phase formation was examined by powder XRD. The morphological changes at different pH derived powders were observed with FE-SEM micrographs. Stepwise organic liberation with respect to temperature and presence of carbon content in the pre-fired powder were analyzed using FT-IR analysis. Raman spectrum reveals disordered tungstate vibrations in the NGW matrix.

Functional Interaction between the Scaffold Protein Kidins220/ARMS and Neuronal Voltage-Gated Na+ Channels.

PubMed

Cesca, Fabrizia; Satapathy, Annyesha; Ferrea, Enrico; Nieus, Thierry; Benfenati, Fabio; Scholz-Starke, Joachim

2015-07-17

Kidins220 (kinase D-interacting substrate of 220 kDa)/ankyrin repeat-rich membrane spanning (ARMS) acts as a signaling platform at the plasma membrane and is implicated in a multitude of neuronal functions, including the control of neuronal activity. Here, we used the Kidins220(-/-) mouse model to study the effects of Kidins220 ablation on neuronal excitability. Multielectrode array recordings showed reduced evoked spiking activity in Kidins220(-/-) hippocampal networks, which was compatible with the increased excitability of GABAergic neurons determined by current-clamp recordings. Spike waveform analysis further indicated an increased sodium conductance in this neuronal subpopulation. Kidins220 association with brain voltage-gated sodium channels was shown by co-immunoprecipitation experiments and Na(+) current recordings in transfected HEK293 cells, which revealed dramatic alterations of kinetics and voltage dependence. Finally, an in silico interneuronal model incorporating the Kidins220-induced Na(+) current alterations reproduced the firing phenotype observed in Kidins220(-/-) neurons. These results identify Kidins220 as a novel modulator of Nav channel activity, broadening our understanding of the molecular mechanisms regulating network excitability. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

Ion channel mechanisms underlying frequency-firing patterns of the avian nucleus magnocellularis: A computational model

PubMed Central

Lu, Ting; Wade, Kirstie; Sanchez, Jason Tait

2017-01-01

ABSTRACT We have previously shown that late-developing avian nucleus magnocellularis (NM) neurons (embryonic [E] days 19–21) fire action potentials (APs) that resembles a band-pass filter in response to sinusoidal current injections of varying frequencies. NM neurons located in the mid- to high-frequency regions of the nucleus fire preferentially at 75 Hz, but only fire a single onset AP to frequency inputs greater than 200 Hz. Surprisingly, NM neurons do not fire APs to sinusoidal inputs less than 20 Hz regardless of the strength of the current injection. In the present study we evaluated intrinsic mechanisms that prevent AP generation to low frequency inputs. We constructed a computational model to simulate the frequency-firing patterns of NM neurons based on experimental data at both room and near physiologic temperatures. The results from our model confirm that the interaction among low- and high-voltage activated potassium channels (KLVA and KHVA, respectively) and voltage dependent sodium channels (NaV) give rise to the frequency-firing patterns observed in vitro. In particular, we evaluated the regulatory role of KLVA during low frequency sinusoidal stimulation. The model shows that, in response to low frequency stimuli, activation of large KLVA current counterbalances the slow-depolarizing current injection, likely permitting NaV closed-state inactivation and preventing the generation of APs. When the KLVA current density was reduced, the model neuron fired multiple APs per sinusoidal cycle, indicating that KLVA channels regulate low frequency AP firing of NM neurons. This intrinsic property of NM neurons may assist in optimizing response to different rates of synaptic inputs. PMID:28481659

Prescribed fires effects on physico-chemical properties and quantity of runoff and soil erosion in a Mediterranean forest

NASA Astrophysics Data System (ADS)

Esteban Lucas-Borja, Manuel; Plaza Alvaréz, Pedro Antonio; Sagra, Javier; Alfaro Sánchez, Raquel; Moya, Daniel; Ferrandiz Gotor, Pablo; De las Heras Ibañez, Jorge

2017-04-01

Wildfires have an important influence in forest ecosystems. Contrary to high severity fire, which may have negative impacts on the ecosystems, low severity induce small changes on soil properties. Thus and in order to reduce fire risk, low-severity prescribed fires have been widely used as a fuel reduction tool and silvicultural treatment in Mediterranean forest ecosystems. However, fire may alter microsite conditions and little is known about the impact of prescribed burning on the physico-chemical properties of runoff. In this study, we compared the effects of prescribed burning on physico-chemical properties and quantity of runoff and soil erosion during twelve months after a low severity prescribed fire applied in twelve 16 m2 plot (6 burned plots and 6 control plots used for comparison) set up in the Lezuza forest (Albacete, central-eastern Spain). Physico-chemical properties and quantity of runoff and soil losses were monitored after each rainfall event (five rainfall events in total). Also, different forest stand characteristics (slope, tree density, basal area and shrub/herbal cover) affecting each plot were measured. Results showed that forest stand characteristics were very similar in all used plots. Also, physico-chemical runoff properties were highly modified after the prescribed fire, increasing water pH, carbonates, bicarbonates, total dissolved solids and organic matter content dissolved in water. Electrical conductivity, calcium, sodium, chloride and magnesium were not affected by prescribed fire. Soil losses were highly related to precipitation intensity and tree interception. Tree intercepted the rainfall and significantly reduced soil losses and also runoff quantity. In conclusion and after the first six-month experiment, the influence of prescribed fires on physico-chemical runoff properties should be taken into account for developing proper prescribed burnings guidelines.

Dendritic sodium channels promote active decorrelation and reduce phase locking to parkinsonian input oscillations in model globus pallidus neurons

PubMed Central

Edgerton, Jeremy R.; Jaeger, Dieter

2011-01-01

Correlated firing among populations of neurons is present throughout the brain and is often rhythmic in nature, observable as an oscillatory fluctuation in the local field potential. Although rhythmic population activity is believed to be critical for normal function in many brain areas, synchronized neural oscillations are associated with disease states in other cases. In the globus pallidus (GP in rodents, homolog of the primate GPe), pairs of neurons generally have uncorrelated firing in normal animals despite an anatomical organization suggesting that they should receive substantial common input. By contrast, correlated and rhythmic GP firing is observed in animal models of Parkinson's disease (PD). Based in part on these findings it has been proposed that an important part of basal ganglia function is active decorrelation, whereby redundant information is compressed. Mechanisms that implement active decorrelation, and changes that cause it to fail in PD, are subjects of great interest. Rat GP neurons express fast, transient voltage-dependent sodium channels (NaF channels) in their dendrites, with the expression level being highest near asymmetric synapses. We recently showed that the dendritic NaF density strongly influences the responsiveness of model GP neurons to synchronous excitatory inputs. In the present study we use rat GP neuron models to show that dendritic NaF channel expression is a potential cellular mechanism of active decorrelation. We further show that model neurons with lower dendritic NaF channel expression have a greater tendency to phase lock with oscillatory synaptic input patterns like those observed in PD. PMID:21795543

The interplay of seven subthreshold conductances controls the resting membrane potential and the oscillatory behavior of thalamocortical neurons

PubMed Central

Zagha, Edward; Mato, German; Rudy, Bernardo; Nadal, Marcela S.

2014-01-01

The signaling properties of thalamocortical (TC) neurons depend on the diversity of ion conductance mechanisms that underlie their rich membrane behavior at subthreshold potentials. Using patch-clamp recordings of TC neurons in brain slices from mice and a realistic conductance-based computational model, we characterized seven subthreshold ion currents of TC neurons and quantified their individual contributions to the total steady-state conductance at levels below tonic firing threshold. We then used the TC neuron model to show that the resting membrane potential results from the interplay of several inward and outward currents over a background provided by the potassium and sodium leak currents. The steady-state conductances of depolarizing Ih (hyperpolarization-activated cationic current), IT (low-threshold calcium current), and INaP (persistent sodium current) move the membrane potential away from the reversal potential of the leak conductances. This depolarization is counteracted in turn by the hyperpolarizing steady-state current of IA (fast transient A-type potassium current) and IKir (inwardly rectifying potassium current). Using the computational model, we have shown that single parameter variations compatible with physiological or pathological modulation promote burst firing periodicity. The balance between three amplifying variables (activation of IT, activation of INaP, and activation of IKir) and three recovering variables (inactivation of IT, activation of IA, and activation of Ih) determines the propensity, or lack thereof, of repetitive burst firing of TC neurons. We also have determined the specific roles that each of these variables have during the intrinsic oscillation. PMID:24760784

SOXAL{trademark} pilot plant demonstration at Niagara Mohawk`s Dunkirk Station

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strangway, P.K.

This paper describes a six-month, nominal three megawatt (3 MW) pilot plant demonstration of the SOXAL{trademark} regenerative flue gas desulfurization (FGD) process at Niagara Mohawk Power Corporation`s Dunkirk, NY coal-fired power station. Using a slip-stream of flue gas from an actual coal-fired boiler, the pilot plant successfully demonstrated the absorption of sulfur dioxide and the simultaneous regeneration of sodium-based scrubbing liquor via bipolar membrane electrodialysis. Sulfur dioxide removal efficiency of greater than 98% was routinely achieved. The absorption and regeneration stages were both proven reliable and controllable. The pilot plant was successfully operated in both continuous and decoupled modes ofmore » operation, thus demonstrating the flexibility of this process.« less

Liquid-metal magnetohydrodynamic system evaluation. [coal-fired designs

NASA Technical Reports Server (NTRS)

Holman, R. R.; Lippert, T. E.

1976-01-01

The present study emphasizes a direct coal-fired design using a bubbly two-component flow of sodium and argon in the MHD generator and a Rankine steam-bottoming plant. Two basic cycles were studied, corresponding to argon temperatures of 922 and 1089 K at the duct inlet. The MHD duct system consisted of multiple ducts arranged in clusters and separated by iron magnet pole pieces. The ducts, each with an output of about 100 MW, were parallel to the flow, but were connected in series electrically to provide a higher MHD voltage. With channel efficiencies of 80%, a pump efficiency of 90%, and a 45% efficient steam-bottoming plant, the overall efficiency of the 1089 K liquid-metal MHD power plant was 43%.

Nitrocobinamide, a New Cyanide Antidote That Can Be Administered by Intramuscular Injection

PubMed Central

Chan, Adriano; Jiang, Jingjing; Fridman, Alla; Guo, Ling T.; Shelton, G. Diane; Liu, Ming-Tao; Green, Carol; Haushalter, Kristofer J.; Patel, Hemal H.; Lee, Jangwoen; Yoon, David; Burney, Tanya; Mukai, David; Mahon, Sari B.; Brenner, Matthew; Pilz, Renate B.; Boss, Gerry R.

2015-01-01

Currently available cyanide antidotes must be given by intravenous injection over 5–10 min, making them illsuited for treating many people in the field, as could occur in a major fire, an industrial accident, or a terrorist attack. These scenarios call for a drug that can be given quickly, e.g., by intramuscular injection. We have shown that aquohydroxocobinamide is a potent cyanide antidote in animal models of cyanide poisoning, but it is unstable in solution and poorly absorbed after intramuscular injection. Here we show that adding sodium nitrite to cobinamide yields a stable derivative (referred to as nitrocobinamide) that rescues cyanide-poisoned mice and rabbits when given by intramuscular injection. We also show that the efficacy of nitrocobinamide is markedly enhanced by coadministering sodium thiosulfate (reducing the total injected volume), and we calculate that ∼1.4 mL each of nitrocobinamide and sodium thiosulfate should rescue a human from a lethal cyanide exposure. PMID:25650735

Slick (Kcnt2) Sodium-Activated Potassium Channels Limit Peptidergic Nociceptor Excitability and Hyperalgesia.

PubMed

Tomasello, Danielle L; Hurley, Edward; Wrabetz, Lawrence; Bhattacharjee, Arin

2017-01-01

The Slick (Kcnt2) sodium-activated potassium (K Na ) channel is a rapidly gating and weakly voltage-dependent and sodium-dependent potassium channel with no clearly defined physiological function. Within the dorsal root ganglia (DRGs), we show Slick channels are exclusively expressed in small-sized and medium-sized calcitonin gene-related peptide (CGRP)-containing DRG neurons, and a pool of channels are localized to large dense-core vesicles (LDCV)-containing CGRP. We stimulated DRG neurons for CGRP release and found Slick channels contained within CGRP-positive LDCV translocated to the neuronal membrane. Behavioral studies in Slick knockout (KO) mice indicated increased basal heat detection and exacerbated thermal hyperalgesia compared with wild-type littermate controls during neuropathic and chronic inflammatory pain. Electrophysiologic recordings of DRG neurons from Slick KO mice revealed that Slick channels contribute to outward current, propensity to fire action potentials (APs), and to AP properties. Our data suggest that Slick channels restrain the excitability of CGRP-containing neurons, diminishing pain behavior after inflammation and injury.

Sodium Heat Pipe Module Processing For the SAFE-100 Reactor Concept

NASA Technical Reports Server (NTRS)

Martin, James; Salvail, Pat

2003-01-01

To support development and hardware-based testing of various space reactor concepts, the Early Flight Fission-Test Facility (EFF-TF) team established a specialized glove box unit with ancillary systems to handle/process alkali metals. Recently, these systems have been commissioned with sodium supporting the fill of stainless steel heat pipe modules for use with a 100 kW thermal heat pipe reactor design. As part of this effort, procedures were developed and refined to govern each segment of the process covering: fill, leak check, vacuum processing, weld closeout, and final "wet in". A series of 316 stainless steel modules, used as precursors to the actual 321 stainless steel modules, were filled with 35 +/- 1 grams of sodium using a known volume canister to control the dispensed mass. Each module was leak checked to less than10(exp -10) std cc/sec helium and vacuum conditioned at 250 C to assist in the removal of trapped gases. A welding procedure was developed to close out the fill stem preventing external gases from entering the evacuated module. Finally the completed modules were vacuum fired at 750 C allowing the sodium to fully wet the internal surface and wick structure of the heat pipe module.

Sodium Heat Pipe Module Processing For the SAFE-100 Reactor Concept

NASA Astrophysics Data System (ADS)

Martin, James; Salvail, Pat

2004-02-01

To support development and hardware-based testing of various space reactor concepts, the Early Flight Fission-Test Facility (EFF-TF) team established a specialized glove box unit with ancillary systems to handle/process alkali metals. Recently, these systems have been commissioned with sodium supporting the fill of stainless steel heat pipe modules for use with a 100 kW thermal heat pipe reactor design. As part of this effort, procedures were developed and refined to govern each segment of the process covering: fill, leak check, vacuum processing, weld closeout, and final ``wet in''. A series of 316 stainless steel modules, used as precursors to the actual 321 stainless steel modules, were filled with 35 +/-1 grams of sodium using a known volume canister to control the dispensed mass. Each module was leak checked to <10-10 std cc/sec helium and vacuum conditioned at 250 °C to assist in the removal of trapped gases. A welding procedure was developed to close out the fill stem preventing external gases from entering the evacuated module. Finally the completed modules were vacuum fired at 750 °C allowing the sodium to fully wet the internal surface and wick structure of the heat pipe module.

Fire-extinguishing organic electrolytes for safe batteries

NASA Astrophysics Data System (ADS)

Wang, Jianhui; Yamada, Yuki; Sodeyama, Keitaro; Watanabe, Eriko; Takada, Koji; Tateyama, Yoshitaka; Yamada, Atsuo

2018-01-01

Severe safety concerns are impeding the large-scale employment of lithium/sodium batteries. Conventional electrolytes are highly flammable and volatile, which may cause catastrophic fires or explosions. Efforts to introduce flame-retardant solvents into the electrolytes have generally resulted in compromised battery performance because those solvents do not suitably passivate carbonaceous anodes. Here we report a salt-concentrated electrolyte design to resolve this dilemma via the spontaneous formation of a robust inorganic passivation film on the anode. We demonstrate that a concentrated electrolyte using a salt and a popular flame-retardant solvent (trimethyl phosphate), without any additives or soft binders, allows stable charge-discharge cycling of both hard-carbon and graphite anodes for more than 1,000 cycles (over one year) with negligible degradation; this performance is comparable or superior to that of conventional flammable carbonate electrolytes. The unusual passivation character of the concentrated electrolyte coupled with its fire-extinguishing property contributes to developing safe and long-lasting batteries, unlocking the limit toward development of much higher energy-density batteries.

Mechanisms and consequences of action potential burst firing in rat neocortical pyramidal neurons

PubMed Central

Williams, Stephen R; Stuart, Greg J

1999-01-01

Electrophysiological recordings and pharmacological manipulations were used to investigate the mechanisms underlying the generation of action potential burst firing and its postsynaptic consequences in visually identified rat layer 5 pyramidal neurons in vitro.Based upon repetitive firing properties and subthreshold membrane characteristics, layer 5 pyramidal neurons were separated into three classes: regular firing and weak and strong intrinsically burst firing.High frequency (330 ± 10 Hz) action potential burst firing was abolished or greatly weakened by the removal of Ca2+ (n = 5) from, or by the addition of the Ca2+ channel antagonist Ni2+ (250–500 μm; n = 8) to, the perfusion medium.The blockade of apical dendritic sodium channels by the local dendritic application of TTX (100 nm; n = 5) abolished or greatly weakened action potential burst firing, as did the local apical dendritic application of Ni2+ (1 mm; n = 5).Apical dendritic depolarisation resulted in low frequency (157 ± 26 Hz; n = 6) action potential burst firing in regular firing neurons, as classified by somatic current injection. The intensity of action potential burst discharges in intrinsically burst firing neurons was facilitated by dendritic depolarisation (n = 11).Action potential amplitude decreased throughout a burst when recorded somatically, suggesting that later action potentials may fail to propagate axonally. Axonal recordings demonstrated that each action potential in a burst is axonally initiated and that no decrement in action potential amplitude is apparent in the axon > 30 μm from the soma.Paired recordings (n = 16) from synaptically coupled neurons indicated that each action potential in a burst could cause transmitter release. EPSPs or EPSCs evoked by a presynaptic burst of action potentials showed use-dependent synaptic depression.A postsynaptic, TTX-sensitive voltage-dependent amplification process ensured that later EPSPs in a burst were amplified when generated from membrane potentials positive to -60 mV, providing a postsynaptic mechanism that counteracts use-dependent depression at synapses between layer 5 pyramidal neurons. PMID:10581316

Effects of a low severity prescribed fire on water-soluble elements in ash from a cork oak (Quercus suber) forest located in the northeast of the Iberian Peninsula

USGS Publications Warehouse

Pereira, P.; beda, X.; Martin, D.; Mataix-Solera, J.; Guerrero, C.

2011-01-01

Wildfire is the major disturbance in Mediterranean forests. Prescribed fire can be an alternative to reduce the amount of fuel and hence decrease the wildfire risk. However the effects of prescribed fire must be studied, especially on ash properties, because ash is an important nutrient source for ecosystem recovery. The aim of this study is to determine the effects of a low severity prescribed fire on water-soluble elements in ash including pH, electrical conductivity (EC), calcium (Ca), magnesium (Mg), sodium (Na), potassium (K), aluminum (Al), manganese (Mn), iron (Fe), zinc (Zn), silica (SiO2) and total sulphur (TS). A prescribed fire was conducted in a cork oak (Quercus suber) (Q.S) forest located in the northeast part of the Iberian Peninsula. Samples were collected from a flat plot of 40??70m mainly composed of Q.S and Quercus robur (Q.R) trees. In order to understand the effects of the prescribed fire on the soluble elements in ash, we conducted our data analysis on three data groups: all samples, only Q.S samples and only Q.R samples. All three sample groups exhibited a significant increase in pH, EC (p<0.001), water-soluble Ca, Mg, Na, SiO2 and TS and a decrease in water-soluble Mn, Fe and Zn. Differences were identified between oak species for water-soluble K, Al and Fe. In Q.S samples we registered a significant increase in the first two elements p<0.001 and p<0.01, respectively, and a non-significant impact in the third, at p<0.05. In Q.R data we identified a non-significant impact on water-soluble K and Al and a significant decrease in water-soluble Fe (p<0.05). These differences are probably due to vegetation characteristics and burn severity. The fire induced a higher variability in the ash soluble elements, especially in Q.S samples, that at some points burned with higher severity. The increase of pH, EC, Ca, Mg, Na and K will improve soil fertility, mainly in the study area where soils are acidic. The application of this low severity prescribed fire will improve soil nutrient status without causing soil degradation and thus is considered to be a good management strategy. ?? 2010 Elsevier Inc.

Effects of a low severity prescribed fire on water-soluble elements in ash from a cork oak (Quercus suber) forest located in the northeast of the Iberian Peninsula.

PubMed

Pereira, Paulo; Ubeda, Xavier; Martin, Deborah; Mataix-Solera, Jorge; Guerrero, César

2011-02-01

Wildfire is the major disturbance in Mediterranean forests. Prescribed fire can be an alternative to reduce the amount of fuel and hence decrease the wildfire risk. However the effects of prescribed fire must be studied, especially on ash properties, because ash is an important nutrient source for ecosystem recovery. The aim of this study is to determine the effects of a low severity prescribed fire on water-soluble elements in ash including pH, electrical conductivity (EC), calcium (Ca), magnesium (Mg), sodium (Na), potassium (K), aluminum (Al), manganese (Mn), iron (Fe), zinc (Zn), silica (SiO(2)) and total sulphur (TS). A prescribed fire was conducted in a cork oak (Quercus suber) (Q.S) forest located in the northeast part of the Iberian Peninsula. Samples were collected from a flat plot of 40×70m mainly composed of Q.S and Quercus robur (Q.R) trees. In order to understand the effects of the prescribed fire on the soluble elements in ash, we conducted our data analysis on three data groups: all samples, only Q.S samples and only Q.R samples. All three sample groups exhibited a significant increase in pH, EC (p<0.001), water-soluble Ca, Mg, Na, SiO(2) and TS and a decrease in water-soluble Mn, Fe and Zn. Differences were identified between oak species for water-soluble K, Al and Fe. In Q.S samples we registered a significant increase in the first two elements p<0.001 and p<0.01, respectively, and a non-significant impact in the third, at p<0.05. In Q.R data we identified a non-significant impact on water-soluble K and Al and a significant decrease in water-soluble Fe (p<0.05). These differences are probably due to vegetation characteristics and burn severity. The fire induced a higher variability in the ash soluble elements, especially in Q.S samples, that at some points burned with higher severity. The increase of pH, EC, Ca, Mg, Na and K will improve soil fertility, mainly in the study area where soils are acidic. The application of this low severity prescribed fire will improve soil nutrient status without causing soil degradation and thus is considered to be a good management strategy. Copyright © 2010 Elsevier Inc. All rights reserved.

Sensor & Model Enabled Water Quality & Security Assessment System for Situational Awareness of Water Distribution Networks

DTIC Science & Technology

2010-06-01

Scenario – 12 gallons of readily available toxic substance – pump ($150 rental) – wrench to open a fire hydrant ($10)  One (1) terrorist, or...6 Gallons Water General Comments Aflatoxin 7.6 Potent Carcinogen Aldicarb 1.1 Cycloheximide 2.1 LSD 0.2 Highly Toxic , Psychoactive Mercuric Chloride...Chlorfenvinphos, Formetanate Hydrochloride, Acrolein, Chloropicrin, Sodium chloroacetate, Thyoglycolate medium, Crotoxyphos, Glyphosate , Jimsonweed, Methanol

Reduction of nitrogen oxides with catalytic acid resistant aluminosilicate molecular sieves and ammonia

DOEpatents

Pence, Dallas T.; Thomas, Thomas R.

1980-01-01

Noxious nitrogen oxides in a waste gas stream such as the stack gas from a fossil-fuel-fired power generation plant or other industrial plant off-gas stream is catalytically reduced to elemental nitrogen and/or innocuous nitrogen oxides employing ammonia as reductant in the presence of a zeolite catalyst in the hydrogen or sodium form having pore openings of about 3 to 10 A.

Knockdown of sodium channel NaV1.6 blocks mechanical pain and abnormal bursting activity of afferent neurons in inflamed sensory ganglia

PubMed Central

Xie, Wenrui; Strong, Judith A.; Ye, Ling; Mao, Ju-Xian; Zhang, Jun-Ming

2013-01-01

Inflammatory processes in the sensory ganglia contribute to many forms of chronic pain. We previously showed that local inflammation of the lumbar sensory ganglia rapidly leads to prolonged mechanical pain behaviors and high levels of spontaneous bursting activity in myelinated cells. Abnormal spontaneous activity of sensory neurons occurs early in many preclinical pain models, and initiates many other pathological changes, but its molecular basis is not well understood. The sodium channel isoform NaV1.6 can underlie repetitive firing and excitatory persistent and resurgent currents. We used in vivo knockdown of this channel via local injection of siRNA to examine its role in chronic pain following local inflammation of the rat lumbar sensory ganglia. In normal DRG, quantitative PCR showed that cells capable of firing repetitively had significantly higher relative expression of NaV1.6. In inflamed DRG, spontaneously active bursting cells expressed high levels of NaV1.6′ immunoreactivity. In vivo knockdown of NaV1.6 locally in the lumbar DRG at the time of DRG inflammation completely blocked development of pain behaviors and abnormal spontaneous activity, while having only minor effects on unmyelinated C-cells. Current research on isoform-specific sodium channel blockers for chronic pain is largely focused on NaV1.8, because it is present primarily in unmyelinated C fiber nociceptors, or on NaV1.7, because lack of this channel causes congenital indifference to pain. However, the results suggest that NaV1.6 may be a useful therapeutic target for chronic pain, and that some pain conditions may be primarily mediated by myelinated A-fiber sensory neurons. PMID:23622763

Calcium Currents of Olfactory Bulb Juxtaglomerular Cells: Profile and Multiple Conductance Plateau Potential Simulation

PubMed Central

Masurkar, Arjun V.; Chen, Wei R.

2011-01-01

The olfactory glomerulus is the locus of information transfer between olfactory sensory neurons and output neurons of the olfactory bulb. Juxtaglomerular cells (JGCs) may influence intraglomerular processing by firing plateau potentials that support multiple spikes. It is unclear what inward currents mediate this firing pattern. In previous work, we characterized potassium currents of JGCs. We focus here on the inward currents using whole cell current clamp and voltage recording in a rat in vitro slice preparation, as well as computer simulation. We first showed that sodium current was not required to mediate plateau potentials. Voltage clamp characterization of calcium current (ICa) determined that ICa consisted of a slow activating, rapidly inactivating (τ10%–90% rise 6–8ms, τinactivation 38–77ms) component Icat1, similar to T-type currents, and a sustained (τinactivation≫500ms) component Icat2, likely composed of L-type and P/Q-type currents. We used computer simulation to test their roles in plateau potential firing. We robustly modeled Icat1 and Icat2 to Hodgkin-Huxley schemes (m3h and m2, respectively) and simulated a JGC plateau potential with 6 conductances: calcium currents as above, potassium currents from our prior study (A-type Ikt1, D-type Ikt2, delayed rectifier Ikt3), and a fast sodium current (INa). We demonstrated that Icat1 was required for mediating the plateau potential, unlike INa and Icat2, and its τinactivation determined plateau duration. We also found that Ikt1 dictated plateau potential shape more than Ikt2 and Ikt3. The influence of these two transient and opposing conductances suggests a unique mechanism of plateau potential physiology. PMID:21704681

Fire flame detection based on GICA and target tracking

NASA Astrophysics Data System (ADS)

Rong, Jianzhong; Zhou, Dechuang; Yao, Wei; Gao, Wei; Chen, Juan; Wang, Jian

2013-04-01

To improve the video fire detection rate, a robust fire detection algorithm based on the color, motion and pattern characteristics of fire targets was proposed, which proved a satisfactory fire detection rate for different fire scenes. In this fire detection algorithm: (a) a rule-based generic color model was developed based on analysis on a large quantity of flame pixels; (b) from the traditional GICA (Geometrical Independent Component Analysis) model, a Cumulative Geometrical Independent Component Analysis (C-GICA) model was developed for motion detection without static background and (c) a BP neural network fire recognition model based on multi-features of the fire pattern was developed. Fire detection tests on benchmark fire video clips of different scenes have shown the robustness, accuracy and fast-response of the algorithm.

Liquid metals for solar power systems

NASA Astrophysics Data System (ADS)

Flesch, J.; Niedermeier, K.; Fritsch, A.; Musaeva, D.; Marocco, L.; Uhlig, R.; Baake, E.; Buck, R.; Wetzel, T.

2017-07-01

The use of liquid metals in solar power systems is not new. The receiver tests with liquid sodium in the 1980s at the Plataforma Solar de Almería (PSA) already proved the feasibility of liquid metals as heat transfer fluid. Despite the high efficiency achieved with that receiver, further investigation of liquid metals in solar power systems was stopped due to a sodium spray fire. Recently, the topic has become interesting again and the gained experience during the last 30 years of liquid metals handling is applied to the concentrated solar power community. In this paper, recent activities of the Helmholtz Alliance LIMTECH concerning liquid metals for solar power systems are presented. In addition to the components and system simulations also the experimental setup and results are included.

Application of the NUREG/CR-6850 EPRI/NRC Fire PRA Methodology to a DOE Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tom Elicson; Bentley Harwood; Richard Yorg

2011-03-01

The application NUREG/CR-6850 EPRI/NRC fire PRA methodology to DOE facility presented several challenges. This paper documents the process and discusses several insights gained during development of the fire PRA. A brief review of the tasks performed is provided with particular focus on the following: • Tasks 5 and 14: Fire-induced risk model and fire risk quantification. A key lesson learned was to begin model development and quantification as early as possible in the project using screening values and simplified modeling if necessary. • Tasks 3 and 9: Fire PRA cable selection and detailed circuit failure analysis. In retrospect, it wouldmore » have been beneficial to perform the model development and quantification in 2 phases with detailed circuit analysis applied during phase 2. This would have allowed for development of a robust model and quantification earlier in the project and would have provided insights into where to focus the detailed circuit analysis efforts. • Tasks 8 and 11: Scoping fire modeling and detailed fire modeling. More focus should be placed on detailed fire modeling and less focus on scoping fire modeling. This was the approach taken for the fire PRA. • Task 14: Fire risk quantification. Typically, multiple safe shutdown (SSD) components fail during a given fire scenario. Therefore dependent failure analysis is critical to obtaining a meaningful fire risk quantification. Dependent failure analysis for the fire PRA presented several challenges which will be discussed in the full paper.« less

Multi-temporal analysis of forest fire risk driven by environmental and socio-economic change in the Republic of Korea

NASA Astrophysics Data System (ADS)

Kim, S. J.; Lim, C. H.; Kim, G. S.; Lee, W. K.

2017-12-01

Analysis of forest fire risk is important in disaster risk reduction (DRR) since it provides a way to manage forest fires. Climate and socio-economic factors are important in the cause of forest fires, and the role of the socio-economic factors in prevention and preparedness of forest fires is increasing. As most of the forest fires in the Republic of Korea are highly related to human activities, both environmental factors and socio-economic factors were considered into the analysis of forest fire risk. In this study, the Maximum Entropy (MaxEnt) model was used to predict the potential geographical distribution and probability of forest fire occurrence spatially and temporally from 1980s to the 2010s in the Republic of Korea by multi-temporal analysis and analyze the relationship between forest fires and the factors. As a result of the risk analysis, there was an overall increasing trend in forest fire risk from the 1980s to the 2000s, and socio-economic factors were highly correlated with the occurrence of forest fires. The study demonstrates that the socio-economic factors considered as human activities can increase the occurrence of forest fires. The result implies that managing human activities are significant to prevent forest fire occurrence. In addition, timely forest fire prevention and control is necessary as drought index such as Standardized Precipitation Index (SPI) also affected forest fires.

Limitations imposed on fire PRA methods as the result of incomplete and uncertain fire event data.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nowlen, Steven Patrick; Hyslop, J. S.

2010-04-01

Fire probabilistic risk assessment (PRA) methods utilize data and insights gained from actual fire events in a variety of ways. For example, fire occurrence frequencies, manual fire fighting effectiveness and timing, and the distribution of fire events by fire source and plant location are all based directly on the historical experience base. Other factors are either derived indirectly or supported qualitatively based on insights from the event data. These factors include the general nature and intensity of plant fires, insights into operator performance, and insights into fire growth and damage behaviors. This paper will discuss the potential methodology improvements thatmore » could be realized if more complete fire event reporting information were available. Areas that could benefit from more complete event reporting that will be discussed in the paper include fire event frequency analysis, analysis of fire detection and suppression system performance including incipient detection systems, analysis of manual fire fighting performance, treatment of fire growth from incipient stages to fully-involved fires, operator response to fire events, the impact of smoke on plant operations and equipment, and the impact of fire-induced cable failures on plant electrical circuits.« less

Post-wildfire management effects on short-term evolution of soil properties (Catalonia, Spain, SW-Europe).

PubMed

Francos, Marcos; Pereira, Paulo; Alcañiz, Meritxell; Úbeda, Xavier

2018-08-15

Post-fire management practices after wildfires have an important impact on soil properties. Nevertheless, little research has been carried out. The aim of this study is to examine the impact of different post-wildfire forest management practices in a 10-month period immediately after a severe wildfire on soil properties. Two months after a wildfire, three experimental areas were designed, each one with different post-fire management: Cut and Remove (CR) where burned trunks were cut after fire and removed manually from the area; No Treatment (NT) where no intervention was carried out; and, Cut and Leave (CL) where burned trunks were cut and left randomly on topsoil. In each treatment, we collected nine samples (0-5cm deep). In total, we sampled 27 samples in each sampling date, two and ten months after the wildfire. The properties analyzed were aggregate stability (AS), total nitrogen (TN), soil organic matter (SOM), inorganic carbon (IC), C/N ratio, pH, electrical conductivity (EC), extractable calcium (Ca), magnesium (Mg), sodium (Na) and potassium (K). Soil C/N ratio was significantly higher in CR and CL treatments 10months after fire comparing to 2months after. On the other hand, pH, extractable Ca, Mg and K were significantly higher in all the treatments 2months after fire than 10months after. Aggregate stability, TN and SOM were significantly higher in CR comparing to CL, 10months after the fire. IC was significantly higher in CL than in NT treatment, also, 10months after the fire. Electrical conductivity was significantly higher in CR and CL treatments 2months after fire comparing to 10months after. According to the results, CR and CL post-fire management did not differ importantly from the NT scenario, showing that manual wood management does not have detrimental impacts on soil properties compared to mechanical operations. Copyright © 2018 Elsevier B.V. All rights reserved.

Sundance Fire: an analysis of fire phenomena

Treesearch

Hal E. Anderson

1968-01-01

The Sundance Fire on September 1, 1967, made a spectacular run of 16 miles in 9 hours and destroyed more than 50,000 acres. This run became the subject of a detailed research analysis of the environmental, topographic, and vegetation variables aimed at reconstructing and describing fire phenomena. This report details the fire's progress; discusses the fire's...

Effects of a fire-retardant chemical to fathead minnows in experimental streams

USGS Publications Warehouse

Calfee, R.D.; Little, E.E.

2003-01-01

Background. Each year millions of liters of fire-retardant chemicals are applied to wildfires across the nation. Recent laboratory studies with long-term fire-retardant chemicals indicate a significant photoenhanced toxicity of products containing sodium ferrocyanide corrosion inhibitors. Our objective of this study was to determine the toxicity of fire-retardant chemicals to fathead minnows during exposure in experimental outdoor streams. Methods. Stream tests were conducted to determine the potential toxicity of a pulse of exposure as might occur when fire retardant chemical is rinsed from the watershed by rainfall. Two artificial 55-meter experimental streams were dosed with different concentrations of Fire-Trol?? GTS-R, or uncontaminated for a control. Replicate groups of fathead minnows were added to screened containers (10 fish per container) and exposed to retardant chemicals in the recirculating flow of the stream for up to 6 hours. Results and Discussion. Under field conditions toxicity of GTS-R only occurred in the presence of sunlight. When GTS-R was tested on sunny days, 100% mortality occurred. However, when tested during heavily overcast conditions, no mortality occurred. Conclusions. Lethal concentrations of cyanide were measured when GTS-R with YPS exposures were conducted under sunny conditions, but not under cloudy conditions, indicating that a minimum UV level is necessary to induce toxicity as well as the release of cyanide from YPS. The toxicity observed with GTS-R was likely associated with lethal concentrations of cyanide. Rainwater runoff following applications of this fire-retardant at the recommended rate could result in lethal concentrations in small ponds and streams receiving limited water flow under sunny conditions. Recommendations and Outlook. In addition to avoiding application to aquatic habitats, it is important to consider characteristics of the treated site including soil binding affinity and erosive properties.

[Analysis of human tissue samples for volatile fire accelerants].

PubMed

Treibs, Rudolf

2014-01-01

In police investigations of fires, the cause of a fire and the fire debris analysis regarding traces of fire accelerants are important aspects for forensic scientists. Established analytical procedures were recently applied to the remains of fire victims. When examining lung tissue samples, vapors inhaled from volatile ignitable liquids could be identified and differentiated from products of pyrolysis caused by the fire. In addition to the medico-legal results this evidence allowed to draw conclusions as to whether the fire victim was still alive when the fire started.

Fire debris analysis for forensic fire investigation using laser induced breakdown spectroscopy (LIBS)

NASA Astrophysics Data System (ADS)

Choi, Soojin; Yoh, Jack J.

2017-08-01

The possibility verification of the first attempt to apply LIBS to arson investigation was performed. LIBS has capabilities for real time in-situ analysis and depth profiling. It can provide valuable information about the fire debris that are complementary to the classification of original sample components and combustion residues. In this study, fire debris was analyzed to determine the ignition source and existence of a fire accelerant using LIBS spectra and depth profiling analysis. Fire debris chemical composition and carbon layer thickness determines the possible ignition source while the carbon layer thickness of combusted samples represents the degree of sample carbonization. When a sample is combusted with fire accelerants, a thicker carbon layer is formed because the burning rate is increased. Therefore, depth profiling can confirm the existence of combustion accelerants, which is evidence of arson. Also investigation of fire debris by depth profiling is still possible when a fire is extinguished with water from fire hose. Such data analysis and in-situ detection of forensic signals via the LIBS may assist fire investigation at crime scenes.

77 FR 37717 - Electrical Cable Test Results and Analysis During Fire Exposure

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-22

... Fire Exposure AGENCY: Nuclear Regulatory Commission. ACTION: Draft NUREG; request for comment. SUMMARY...-2128, ``Electrical Cable Test Results and Analysis during Fire Exposure (ELECTRA-FIRE), A Consolidation of the Three Major Fire-Induced Circuit and Cable Failure Experiments Performed between 2001 and 2011...

Assessing the accuracy of wildland fire situation analysis (WFSA) fire size and suppression cost estimates.

Treesearch

Geoffrey H. Donovan; Peter. Noordijk

2005-01-01

To determine the optimal suppression strategy for escaped wildfires, federal land managers are requiredto conduct a wildland fire situation analysis (WFSA). As part of the WFSA process, fire managers estimate final fire size and suppression costs. Estimates from 58 WFSAs conducted during the 2002 fire season are compared to actual outcomes. Results indicate that...

Visibility analysis of fire lookout towers in the Boyabat State Forest Enterprise in Turkey.

PubMed

Kucuk, Omer; Topaloglu, Ozer; Altunel, Arif Oguz; Cetin, Mehmet

2017-07-01

For a successful fire suppression, it is essential to detect and intervene forest fires as early as possible. Fire lookout towers are crucial assets in detecting forest fires, in addition to other technological advancements. In this study, we performed a visibility analysis on a network of fire lookout towers currently operating in a relatively fire-prone region in Turkey's Western Black Sea region. Some of these towers had not been functioning properly; it was proposed that these be taken out of the grid and replaced with new ones. The percentage of visible areas under the current network of fire lookout towers was 73%; it could rise to 81% with the addition of newly proposed towers. This study was the first research to conduct a visibility analysis of current and newly proposed fire lookout towers in the Western Black Sea region and focus on its forest fire problem.

Integrating fire management analysis into land management planning

Treesearch

Thomas J. Mills

1983-01-01

The analysis of alternative fire management programs should be integrated into the land and resource management planning process, but a single fire management analysis model cannot meet all planning needs. Therefore, a set of simulation models that are analytically separate from integrated land management planning models are required. The design of four levels of fire...

Sodium channel slow inactivation as a therapeutic target for myotonia congenita

PubMed Central

Novak, Kevin R; Norman, Jennifer; Mitchell, Jacob R; Pinter, Martin J; Rich, Mark M

2014-01-01

Objective Patients with myotonia congenita have muscle hyperexcitability due to loss-of-function mutations in the chloride channel in skeletal muscle, which causes spontaneous firing of muscle action potentials (myotonia), producing muscle stiffness. In patients, muscle stiffness lessens with exercise, a change known as the warm-up phenomenon. Our goal was to identify the mechanism underlying warm up and to use this information to guide development of novel therapy. Methods To determine the mechanism underlying warm-up, we used a recently discovered drug to eliminate muscle contraction, thus allowing prolonged intracellular recording from individual muscle fibers during induction of warm-up in a mouse model of myotonia congenita. Results Changes in action potentials suggested slow inactivation of sodium channels as an important contributor to warm-up. These data suggested enhancing slow inactivation of sodium channels might offer effective therapy for myotonia. Lacosamide and ranolazine enhance slow inactivation of sodium channels and are FDA-approved for other uses in patients. We compared the efficacy of both drugs to mexiletine, a sodium channel blocker currently used to treat myotonia. In vitro studies suggested both lacosamide and ranolazine were superior to mexiletine. However, in vivo studies in a mouse model of myotonia congenita suggested side effects could limit the efficacy of lacosamide. Ranolazine produced fewer side effects and was as effective as mexiletine at a dose that produced none of mexiletine’s hypoexcitability side effects. Interpretation We conclude ranolazine has excellent therapeutic potential for treatment of patients with myotonia congenita. PMID:25515836

Forest fires in Pennsylvania.

Treesearch

Donald A. Haines; William A. Main; Eugene F. McNamara

1978-01-01

Describes factors that contribute to forest fires in Pennsylvania. Includes an analysis of basic statistics; distribution of fires during normal, drought, and wet years; fire cause, fire activity by day-of-week; multiple-fire day; and fire climatology.

Combustion inorganic transformations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benson, S.A.; Sweeny, P.G.; Abrahamson, H.B.

1988-04-01

The overall goal of the project is to develop a unified picture of the physical and chemical changes that occur in coal inorganic matter during combustion. The research is centered on two main tasks. Task 3.2A deals with the use of laser-induced fluorescence spectroscopy (LIFS) to study the release of sodium from various model compounds and coal during combustion in a flame. The vaporized or released sodium is considered to be an important factor in the formation of ash fouling deposits in full-scale utility boilers. Task 3.2B will study changes in the morphology and chemical associations of inorganic components inmore » coals during combustion in a drop-tube furnace designed to simulate the time-temperature profile of a pulverized coal-fired utility boiler. Results are described. 18 refs., 51 figs., 28 tabs.« less

How noise affects the synchronization properties of recurrent networks of inhibitory neurons.

PubMed

Brunel, Nicolas; Hansel, David

2006-05-01

GABAergic interneurons play a major role in the emergence of various types of synchronous oscillatory patterns of activity in the central nervous system. Motivated by these experimental facts, modeling studies have investigated mechanisms for the emergence of coherent activity in networks of inhibitory neurons. However, most of these studies have focused either when the noise in the network is absent or weak or in the opposite situation when it is strong. Hence, a full picture of how noise affects the dynamics of such systems is still lacking. The aim of this letter is to provide a more comprehensive understanding of the mechanisms by which the asynchronous states in large, fully connected networks of inhibitory neurons are destabilized as a function of the noise level. Three types of single neuron models are considered: the leaky integrate-and-fire (LIF) model, the exponential integrate-and-fire (EIF), model and conductance-based models involving sodium and potassium Hodgkin-Huxley (HH) currents. We show that in all models, the instabilities of the asynchronous state can be classified in two classes. The first one consists of clustering instabilities, which exist in a restricted range of noise. These instabilities lead to synchronous patterns in which the population of neurons is broken into clusters of synchronously firing neurons. The irregularity of the firing patterns of the neurons is weak. The second class of instabilities, termed oscillatory firing rate instabilities, exists at any value of noise. They lead to cluster state at low noise. As the noise is increased, the instability occurs at larger coupling, and the pattern of firing that emerges becomes more irregular. In the regime of high noise and strong coupling, these instabilities lead to stochastic oscillations in which neurons fire in an approximately Poisson way with a common instantaneous probability of firing that oscillates in time.

Influence of stimulus and oral adaptation temperature on gustatory responses in central taste-sensitive neurons

PubMed Central

Li, Jinrong

2015-01-01

The temperature of taste stimuli can modulate gustatory processing. Perceptual data indicate that the adapted temperature of oral epithelia also influences gustation, although little is known about the neural basis of this effect. Here, we electrophysiologically recorded orosensory responses (spikes) to 25°C (cool) and 35°C (warm) solutions of sucrose (0.1 and 0.3 M), NaCl (0.004, 0.1, and 0.3 M), and water from taste-sensitive neurons in the nucleus of the solitary tract in mice under varied thermal adaptation of oral epithelia. Conditions included presentation of taste stimuli isothermal to adaptation temperatures of 25°C (constant cooling) and 35°C (constant warming), delivery of 25°C stimuli following 35°C adaptation (relative cooling), and presentation of 35°C stimuli following 25°C adaptation (relative warming). Responses to sucrose in sucrose-oriented cells (n = 15) were enhanced under the constant and relative warming conditions compared with constant cooling, where contiguous cooling across adaptation and stimulus periods induced the lowest and longest latency responses to sucrose. Yet compared with constant warming, cooling sucrose following warm adaptation (relative cooling) only marginally reduced activity to 0.1 M sucrose and did not alter responses to 0.3 M sucrose. Thus, warmth adaptation counteracted the attenuation in sucrose activity associated with stimulus cooling. Analysis of sodium-oriented (n = 25) neurons revealed adaptation to cool water, and cooling taste solutions enhanced unit firing to 0.004 M (perithreshold) NaCl, whereas warmth adaptation and stimulus warming could facilitate activity to 0.3 M NaCl. The concentration dependence of this thermal effect may reflect a dual effect of temperature on the sodium reception mechanism that drives sodium-oriented cells. PMID:25673737

Contribution of suppression difficulty and lessons learned in forecasting fire suppression operations productivity: A methodological approach

Treesearch

Francisco Rodríguez y Silva; Armando González-Cabán

2016-01-01

We propose an economic analysis using utility and productivity, and efficiency theories to provide fire managers a decision support tool to determine the most efficient fire management programs levels. By incorporating managers’ accumulated fire suppression experiences (capitalized experience) in the analysis we help fire managers...

Survival analysis and classification methods for forest fire size

PubMed Central

2018-01-01

Factors affecting wildland-fire size distribution include weather, fuels, and fire suppression activities. We present a novel application of survival analysis to quantify the effects of these factors on a sample of sizes of lightning-caused fires from Alberta, Canada. Two events were observed for each fire: the size at initial assessment (by the first fire fighters to arrive at the scene) and the size at “being held” (a state when no further increase in size is expected). We developed a statistical classifier to try to predict cases where there will be a growth in fire size (i.e., the size at “being held” exceeds the size at initial assessment). Logistic regression was preferred over two alternative classifiers, with covariates consistent with similar past analyses. We conducted survival analysis on the group of fires exhibiting a size increase. A screening process selected three covariates: an index of fire weather at the day the fire started, the fuel type burning at initial assessment, and a factor for the type and capabilities of the method of initial attack. The Cox proportional hazards model performed better than three accelerated failure time alternatives. Both fire weather and fuel type were highly significant, with effects consistent with known fire behaviour. The effects of initial attack method were not statistically significant, but did suggest a reverse causality that could arise if fire management agencies were to dispatch resources based on a-priori assessment of fire growth potentials. We discuss how a more sophisticated analysis of larger data sets could produce unbiased estimates of fire suppression effect under such circumstances. PMID:29320497

Survival analysis and classification methods for forest fire size.

PubMed

Tremblay, Pier-Olivier; Duchesne, Thierry; Cumming, Steven G

2018-01-01

Factors affecting wildland-fire size distribution include weather, fuels, and fire suppression activities. We present a novel application of survival analysis to quantify the effects of these factors on a sample of sizes of lightning-caused fires from Alberta, Canada. Two events were observed for each fire: the size at initial assessment (by the first fire fighters to arrive at the scene) and the size at "being held" (a state when no further increase in size is expected). We developed a statistical classifier to try to predict cases where there will be a growth in fire size (i.e., the size at "being held" exceeds the size at initial assessment). Logistic regression was preferred over two alternative classifiers, with covariates consistent with similar past analyses. We conducted survival analysis on the group of fires exhibiting a size increase. A screening process selected three covariates: an index of fire weather at the day the fire started, the fuel type burning at initial assessment, and a factor for the type and capabilities of the method of initial attack. The Cox proportional hazards model performed better than three accelerated failure time alternatives. Both fire weather and fuel type were highly significant, with effects consistent with known fire behaviour. The effects of initial attack method were not statistically significant, but did suggest a reverse causality that could arise if fire management agencies were to dispatch resources based on a-priori assessment of fire growth potentials. We discuss how a more sophisticated analysis of larger data sets could produce unbiased estimates of fire suppression effect under such circumstances.

FIRES: Fire Information Retrieval and Evaluation System - A program for fire danger rating analysis

Treesearch

Patricia L. Andrews; Larry S. Bradshaw

1997-01-01

A computer program, FIRES: Fire Information Retrieval and Evaluation System, provides methods for evaluating the performance of fire danger rating indexes. The relationship between fire danger indexes and historical fire occurrence and size is examined through logistic regression and percentiles. Historical seasonal trends of fire danger and fire occurrence can be...

Application of Graph Theory to Cost-Effective Fire Protection of Chemical Plants During Domino Effects.

PubMed

Khakzad, Nima; Landucci, Gabriele; Reniers, Genserik

2017-09-01

In the present study, we have introduced a methodology based on graph theory and multicriteria decision analysis for cost-effective fire protection of chemical plants subject to fire-induced domino effects. By modeling domino effects in chemical plants as a directed graph, the graph centrality measures such as out-closeness and betweenness scores can be used to identify the installations playing a key role in initiating and propagating potential domino effects. It is demonstrated that active fire protection of installations with the highest out-closeness score and passive fire protection of installations with the highest betweenness score are the most effective strategies for reducing the vulnerability of chemical plants to fire-induced domino effects. We have employed a dynamic graph analysis to investigate the impact of both the availability and the degradation of fire protection measures over time on the vulnerability of chemical plants. The results obtained from the graph analysis can further be prioritized using multicriteria decision analysis techniques such as the method of reference point to find the most cost-effective fire protection strategy. © 2016 Society for Risk Analysis.

Alterations of sodium and potassium channels of RGCs in RCS rat with the development of retinal degeneration.

PubMed

Chen, Zhongshan; Song, Yanping; Yao, Junping; Weng, Chuanhuang; Yin, Zheng Qin

2013-11-01

All know that retinitis pigmentosa (RP) is a group of hereditary retinal degenerative diseases characterized by progressive dysfunction of photoreceptors and associated with progressive cells loss; nevertheless, little is known about how rods and cones loss affects the surviving inner retinal neurons and networks. Retinal ganglion cells (RGCs) process and convey visual information from retina to visual centers in the brain. The healthy various ion channels determine the normal reception and projection of visual signals from RGCs. Previous work on the Royal College of Surgeons (RCS) rat, as a kind of classical RP animal model, indicated that, at late stages of retinal degeneration in RCS rat, RGCs were also morphologically and functionally affected. Here, retrograde labeling for RGCs with Fluorogold was performed to investigate the distribution, density, and morphological changes of RGCs during retinal degeneration. Then, patch clamp recording, western blot, and immunofluorescence staining were performed to study the channels of sodium and potassium properties of RGCs, so as to explore the molecular and proteinic basis for understanding the alterations of RGCs membrane properties and firing functions. We found that the resting membrane potential, input resistance, and capacitance of RGCs changed significantly at the late stage of retinal degeneration. Action potential could not be evoked in a part of RGCs. Inward sodium current and outward potassium current recording showed that sodium current was impaired severely but only slightly in potassium current. Expressions of sodium channel protein were impaired dramatically at the late stage of retinal degeneration. The results suggested that the density of RGCs decreased, process ramification impaired, and sodium ion channel proteins destructed, which led to the impairment of electrophysiological functions of RGCs and eventually resulted in the loss of visual function.

Heat Transfer Principles in Thermal Calculation of Structures in Fire

PubMed Central

Zhang, Chao; Usmani, Asif

2016-01-01

Structural fire engineering (SFE) is a relatively new interdisciplinary subject, which requires a comprehensive knowledge of heat transfer, fire dynamics and structural analysis. It is predominantly the community of structural engineers who currently carry out most of the structural fire engineering research and design work. The structural engineering curriculum in universities and colleges do not usually include courses in heat transfer and fire dynamics. In some institutions of higher education, there are graduate courses for fire resistant design which focus on the design approaches in codes. As a result, structural engineers who are responsible for structural fire safety and are competent to do their jobs by following the rules specified in prescriptive codes may find it difficult to move toward performance-based fire safety design which requires a deep understanding of both fire and heat. Fire safety engineers, on the other hand, are usually focused on fire development and smoke control, and may not be familiar with the heat transfer principles used in structural fire analysis, or structural failure analysis. This paper discusses the fundamental heat transfer principles in thermal calculation of structures in fire, which might serve as an educational guide for students, engineers and researchers. Insights on problems which are commonly ignored in performance based fire safety design are also presented. PMID:26783379

Modeling Payload Stowage Impacts on Fire Risks On-Board the International Space Station

NASA Technical Reports Server (NTRS)

Anton, Kellie e.; Brown, Patrick F.

2010-01-01

The purpose of this presentation is to determine the risks of fire on-board the ISS due to non-standard stowage. ISS stowage is constantly being reexamined for optimality. Non-standard stowage involves stowing items outside of rack drawers, and fire risk is a key concern and is heavily mitigated. A Methodology is needed to account for fire risk due to non-standard stowage to capture the risk. The contents include: 1) Fire Risk Background; 2) General Assumptions; 3) Modeling Techniques; 4) Event Sequence Diagram (ESD); 5) Qualitative Fire Analysis; 6) Sample Qualitative Results for Fire Risk; 7) Qualitative Stowage Analysis; 8) Sample Qualitative Results for Non-Standard Stowage; and 9) Quantitative Analysis Basic Event Data.

Comparison of sodium content of workplace and homemade meals through chemical analysis and salinity measurements.

PubMed

Shin, Eun-Kyung; Lee, Yeon-Kyung

2014-10-01

Most Koreans consume nearly 70-80% of the total sodium through their dishes. The use of a salinometer to measure salinity is recommended to help individuals control their sodium intake. The purpose of this study was to compare sodium content through chemical analysis and salinity measurement in foods served by industry foodservice operations and homemade meals. Workplace and homemade meals consumed by employees in 15 cafeterias located in 8 districts in Daegu were collected and the sodium content was measured through chemical analysis and salinity measurements and then compared. The foods were categorized into 9 types of menus with 103 workplace meals and 337 homemade meals. Workplace meals did not differ significantly in terms of sodium content per 100 g of food but had higher sodium content via chemical analysis in roasted foods per portion. Homemade meals had higher broth salt content and higher salt content by chemical analysis per 100 g of roasted foods and hard-boiled foods. One-dish workplace meals had higher salinity (P < 0.05), while homemade broths and stews had higher sodium content (P < 0.05 and P < 0.01, respectively). The sodium content per 100 g of foods was higher in one-dish workplace meals (P < 0.05) and in homemade broths and stews (P < 0.01 and P < 0.05, respectively). The use of a salinometer may be recommended to estimate the sodium content in foods and control one's sodium intake within the daily intake target as a way to promote cooking bland foods at home. However, estimated and actual measured values may differ.

Potassium Sodium Niobate-Based Lead-Free Piezoelectric Multilayer Ceramics Co-Fired with Nickel Electrodes.

PubMed

Kawada, Shinichiro; Hayashi, Hiroyuki; Ishii, Hideki; Kimura, Masahiko; Ando, Akira; Omiya, Suetake; Kubodera, Noriyuki

2015-11-03

Although lead-free piezoelectric ceramics have been extensively studied, many problems must still be overcome before they are suitable for practical use. One of the main problems is fabricating a multilayer structure, and one solution attracting growing interest is the use of lead-free multilayer piezoelectric ceramics. The paper reviews work that has been done by the authors on lead-free alkali niobate-based multilayer piezoelectric ceramics co-fired with nickel inner electrodes. Nickel inner electrodes have many advantages, such as high electromigration resistance, high interfacial strength with ceramics, and greater cost effectiveness than silver palladium inner electrodes. However, widely used lead zirconate titanate-based ceramics cannot be co-fired with nickel inner electrodes, and silver palladium inner electrodes are usually used for lead zirconate titanate-based piezoelectric ceramics. A possible alternative is lead-free ceramics co-fired with nickel inner electrodes. We have thus been developing lead-free alkali niobate-based multilayer ceramics co-fired with nickel inner electrodes. The normalized electric-field-induced thickness strain ( S max / E max ) of a representative alkali niobate-based multilayer ceramic structure with nickel inner electrodes was 360 pm/V, where S max denotes the maximum strain and E max denotes the maximum electric field. This value is about half that for the lead zirconate titanate-based ceramics that are widely used. However, a comparable value can be obtained by stacking more ceramic layers with smaller thicknesses. In the paper, the compositional design and process used to co-fire lead-free ceramics with nickel inner electrodes are introduced, and their piezoelectric properties and reliabilities are shown. Recent advances are introduced, and future development is discussed.

Control of clustered action potential firing in a mathematical model of entorhinal cortex stellate cells.

PubMed

Tait, Luke; Wedgwood, Kyle; Tsaneva-Atanasova, Krasimira; Brown, Jon T; Goodfellow, Marc

2018-07-14

The entorhinal cortex is a crucial component of our memory and spatial navigation systems and is one of the first areas to be affected in dementias featuring tau pathology, such as Alzheimer's disease and frontotemporal dementia. Electrophysiological recordings from principle cells of medial entorhinal cortex (layer II stellate cells, mEC-SCs) demonstrate a number of key identifying properties including subthreshold oscillations in the theta (4-12 Hz) range and clustered action potential firing. These single cell properties are correlated with network activity such as grid firing and coupling between theta and gamma rhythms, suggesting they are important for spatial memory. As such, experimental models of dementia have revealed disruption of organised dorsoventral gradients in clustered action potential firing. To better understand the mechanisms underpinning these different dynamics, we study a conductance based model of mEC-SCs. We demonstrate that the model, driven by extrinsic noise, can capture quantitative differences in clustered action potential firing patterns recorded from experimental models of tau pathology and healthy animals. The differential equation formulation of our model allows us to perform numerical bifurcation analyses in order to uncover the dynamic mechanisms underlying these patterns. We show that clustered dynamics can be understood as subcritical Hopf/homoclinic bursting in a fast-slow system where the slow sub-system is governed by activation of the persistent sodium current and inactivation of the slow A-type potassium current. In the full system, we demonstrate that clustered firing arises via flip bifurcations as conductance parameters are varied. Our model analyses confirm the experimentally suggested hypothesis that the breakdown of clustered dynamics in disease occurs via increases in AHP conductance. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Potassium Sodium Niobate-Based Lead-Free Piezoelectric Multilayer Ceramics Co-Fired with Nickel Electrodes

PubMed Central

Kawada, Shinichiro; Hayashi, Hiroyuki; Ishii, Hideki; Kimura, Masahiko; Ando, Akira; Omiya, Suetake; Kubodera, Noriyuki

2015-01-01

Although lead-free piezoelectric ceramics have been extensively studied, many problems must still be overcome before they are suitable for practical use. One of the main problems is fabricating a multilayer structure, and one solution attracting growing interest is the use of lead-free multilayer piezoelectric ceramics. The paper reviews work that has been done by the authors on lead-free alkali niobate-based multilayer piezoelectric ceramics co-fired with nickel inner electrodes. Nickel inner electrodes have many advantages, such as high electromigration resistance, high interfacial strength with ceramics, and greater cost effectiveness than silver palladium inner electrodes. However, widely used lead zirconate titanate-based ceramics cannot be co-fired with nickel inner electrodes, and silver palladium inner electrodes are usually used for lead zirconate titanate-based piezoelectric ceramics. A possible alternative is lead-free ceramics co-fired with nickel inner electrodes. We have thus been developing lead-free alkali niobate-based multilayer ceramics co-fired with nickel inner electrodes. The normalized electric-field-induced thickness strain (Smax/Emax) of a representative alkali niobate-based multilayer ceramic structure with nickel inner electrodes was 360 pm/V, where Smax denotes the maximum strain and Emax denotes the maximum electric field. This value is about half that for the lead zirconate titanate-based ceramics that are widely used. However, a comparable value can be obtained by stacking more ceramic layers with smaller thicknesses. In the paper, the compositional design and process used to co-fire lead-free ceramics with nickel inner electrodes are introduced, and their piezoelectric properties and reliabilities are shown. Recent advances are introduced, and future development is discussed. PMID:28793646

Cryogenic method for measuring nuclides and fission gases

DOEpatents

Perdue, P.T.; Haywood, F.F.

1980-05-02

A cryogenic method is provided for determining airborne gases and particulates from which gamma rays are emitted. A special dewar counting vessel is filled with the contents of the sampling flask which is immersed in liquid nitrogen. A vertically placed sodium-iodide or germanium-lithium gamma-ray detector is used. The device and method are of particular use in measuring and identifying the radioactive noble gases including emissions from coal-fired power plants, as well as fission gases released or escaping from nuclear power plants.

Detection, monitoring, and quantitative analysis of wildfires with the BIRD satellite

NASA Astrophysics Data System (ADS)

Oertel, Dieter A.; Briess, Klaus; Lorenz, Eckehard; Skrbek, Wolfgang; Zhukov, Boris

2004-02-01

Increasing concern about environment and interest to avoid losses led to growing demands on space borne fire detection, monitoring and quantitative parameter estimation of wildfires. The global change research community intends to quantify the amount of gaseous and particulate matter emitted from vegetation fires, peat fires and coal seam fires. The DLR Institute of Space Sensor Technology and Planetary Exploration (Berlin-Adlershof) developed a small satellite called BIRD (Bi-spectral Infrared Detection) which carries a sensor package specially designed for fire detection. BIRD was launched as a piggy-back satellite on October 22, 2001 with ISRO"s Polar Satellite Launch Vehicle (PSLV). It is circling the Earth on a polar and sun-synchronous orbit at an altitude of 572 km and it is providing unique data for detailed analysis of high temperature events on Earth surface. The BIRD sensor package is dedicated for high resolution and reliable fire recognition. Active fire analysis is possible in the sub-pixel domain. The leading channel for fire detection and monitoring is the MIR channel at 3.8 μm. The rejection of false alarms is based on procedures using MIR/NIR (Middle Infra Red/Near Infra Red) and MIR/TIR (Middle Infra Red/Thermal Infra Red) radiance ratio thresholds. Unique results of BIRD wildfire detection and analysis over fire prone regions in Australia and Asia will be presented. BIRD successfully demonstrates innovative fire recognition technology for small satellites which permit to retrieve quantitative characteristics of active burning wildfires, such as the equivalent fire temperature, fire area, radiative energy release, fire front length and fire front strength.

Analysis of the Influence of Construction Insulation Systems on Public Safety in China

PubMed Central

Zhang, Guowei; Zhu, Guoqing; Zhao, Guoxiang

2016-01-01

With the Government of China’s proposed Energy Efficiency Regulations (GB40411-2007), the implementation of external insulation systems will be mandatory in China. The frequent external insulation system fires cause huge numbers of casualties and extensive property damage and have rapidly become a new hot issue in construction evacuation safety in China. This study attempts to reconstruct an actual fire scene and propose a quantitative risk assessment method for upward insulation system fires using thermal analysis tests and large eddy simulations (using the Fire Dynamics Simulator (FDS) software). Firstly, the pyrolysis and combustion characteristics of Extruded polystyrene board (XPS panel), such as ignition temperature, combustion heat, limiting oxygen index, thermogravimetric analysis and thermal radiation analysis were studied experimentally. Based on these experimental data, large eddy simulation was then applied to reconstruct insulation system fires. The results show that upward insulation system fires could be accurately reconstructed by using thermal analysis test and large eddy simulation. The spread of insulation material system fires in the vertical direction is faster than that in the horizontal direction. Moreover, we also find that there is a possibility of flashover in enclosures caused by insulation system fires as the smoke temperature exceeds 600 °C. The simulation methods and experimental results obtained in this paper could provide valuable references for fire evacuation, hazard assessment and fire resistant construction design studies. PMID:27589774

Analysis of the Influence of Construction Insulation Systems on Public Safety in China.

PubMed

Zhang, Guowei; Zhu, Guoqing; Zhao, Guoxiang

2016-08-30

With the Government of China's proposed Energy Efficiency Regulations (GB40411-2007), the implementation of external insulation systems will be mandatory in China. The frequent external insulation system fires cause huge numbers of casualties and extensive property damage and have rapidly become a new hot issue in construction evacuation safety in China. This study attempts to reconstruct an actual fire scene and propose a quantitative risk assessment method for upward insulation system fires using thermal analysis tests and large eddy simulations (using the Fire Dynamics Simulator (FDS) software). Firstly, the pyrolysis and combustion characteristics of Extruded polystyrene board (XPS panel), such as ignition temperature, combustion heat, limiting oxygen index, thermogravimetric analysis and thermal radiation analysis were studied experimentally. Based on these experimental data, large eddy simulation was then applied to reconstruct insulation system fires. The results show that upward insulation system fires could be accurately reconstructed by using thermal analysis test and large eddy simulation. The spread of insulation material system fires in the vertical direction is faster than that in the horizontal direction. Moreover, we also find that there is a possibility of flashover in enclosures caused by insulation system fires as the smoke temperature exceeds 600 °C. The simulation methods and experimental results obtained in this paper could provide valuable references for fire evacuation, hazard assessment and fire resistant construction design studies.

Assessment of fire effects based on Forest Inventory and Analysis data and a long-term fire mapping data set

Treesearch

John D. Shaw; Sara A. Goeking; James Menlove; Charles E. Werstak

2017-01-01

Integration of Forest Inventory and Analysis (FIA) plot data with Monitoring Trends in Burn Severity (MTBS) data can provide new information about fire effects on forests. This integration allowed broad-scale assessment of the cover types burned in large fires, the relationship between prefire stand conditions and fire severity, and postfire stand conditions. Of the 42...

Bald Mountain Fire, Eagle Cap Wilderness Area, Wallowa-Whitman National Forest, FARSITE analysis

Treesearch

LaWen Hollingsworth

2012-01-01

While the Near Term Fire Behavior analysis option in WFDSS is similar to FARSITE, the advantage of using FARSITE lies in the ability to use gridded winds which produces more reliable fire behavior results in complex terrain. A couple of FARSITE simulations were completed to evaluate fire growth and fire behavior in relation to the values, notably Red's Horse Ranch...

Analysis of NASA JP-4 fire tests data and development of a simple fire model

NASA Technical Reports Server (NTRS)

Raj, P.

1980-01-01

The temperature, velocity and species concentration data obtained during the NASA fire tests (3m, 7.5m and 15m diameter JP-4 fires) were analyzed. Utilizing the data analysis, a sample theoretical model was formulated to predict the temperature and velocity profiles in JP-4 fires. The theoretical model, which does not take into account the detailed chemistry of combustion, is capable of predicting the extent of necking of the fire near its base.

Southwestern Oregon's Biscuit Fire: An Analysis of Forest Resources, Fire Severity, and Fire Hazard

Treesearch

David L. Azuma; Glenn A. Christensen

2005-01-01

This study compares pre-fire field inventory data (collected from 1993 to 1997) in relation to post-fire mapped fire severity classes and the Fire and Fuels Extension of the Forest Vegetation Simulator growth and yield model measures of fire hazard for the portion of the Siskiyou National Forest in the 2002 Biscuit fire perimeter of southwestern Oregon. Post-fire...

Voltage-gated sodium channels in taste bud cells.

PubMed

Gao, Na; Lu, Min; Echeverri, Fernando; Laita, Bianca; Kalabat, Dalia; Williams, Mark E; Hevezi, Peter; Zlotnik, Albert; Moyer, Bryan D

2009-03-12

Taste bud cells transmit information regarding the contents of food from taste receptors embedded in apical microvilli to gustatory nerve fibers innervating basolateral membranes. In particular, taste cells depolarize, activate voltage-gated sodium channels, and fire action potentials in response to tastants. Initial cell depolarization is attributable to sodium influx through TRPM5 in sweet, bitter, and umami cells and an undetermined cation influx through an ion channel in sour cells expressing PKD2L1, a candidate sour taste receptor. The molecular identity of the voltage-gated sodium channels that sense depolarizing signals and subsequently initiate action potentials coding taste information to gustatory nerve fibers is unknown. We describe the molecular and histological expression profiles of cation channels involved in electrical signal transmission from apical to basolateral membrane domains. TRPM5 was positioned immediately beneath tight junctions to receive calcium signals originating from sweet, bitter, and umami receptor activation, while PKD2L1 was positioned at the taste pore. Using mouse taste bud and lingual epithelial cells collected by laser capture microdissection, SCN2A, SCN3A, and SCN9A voltage-gated sodium channel transcripts were expressed in taste tissue. SCN2A, SCN3A, and SCN9A were expressed beneath tight junctions in subsets of taste cells. SCN3A and SCN9A were expressed in TRPM5 cells, while SCN2A was expressed in TRPM5 and PKD2L1 cells. HCN4, a gene previously implicated in sour taste, was expressed in PKD2L1 cells and localized to cell processes beneath the taste pore. SCN2A, SCN3A and SCN9A voltage-gated sodium channels are positioned to sense initial depolarizing signals stemming from taste receptor activation and initiate taste cell action potentials. SCN2A, SCN3A and SCN9A gene products likely account for the tetrodotoxin-sensitive sodium currents in taste receptor cells.

Using the Large Fire Simulator System to map wildland fire potential for the conterminous United States

Treesearch

LaWen Hollingsworth; James Menakis

2010-01-01

This project mapped wildland fire potential (WFP) for the conterminous United States by using the large fire simulation system developed for Fire Program Analysis (FPA) System. The large fire simulation system, referred to here as LFSim, consists of modules for weather generation, fire occurrence, fire suppression, and fire growth modeling. Weather was generated with...

Comparative Analysis of Fusion Center Outreach to Fire and EMS Agencies

DTIC Science & Technology

2015-12-01

ANALYSIS OF FUSION CENTER OUTREACH TO FIRE AND EMS AGENCIES by Scott E. Goldstein December 2015 Thesis Advisor: Fathali Moghaddam Second...REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE COMPARATIVE ANALYSIS OF FUSION CENTER OUTREACH TO FIRE AND EMS AGENCIES 5...public release; distribution is unlimited 12b. DISTRIBUTION CODE A 13. ABSTRACT (maximum 200 words) Fire and EMS responders have had little

The Redesigned Hazard Mapping System (HMS) for Fire and Smoke Analysis and the Impact of Including Visible Infrared Imaging Radiometer Suite (VIIRS) Data

NASA Astrophysics Data System (ADS)

Ruminski, M.; Cheng, Z.; Salemi, T.

2016-12-01

The HMS incorporates a wide variety of satellite data for use in fire and smoke detection, including 30 minute interval GOES-East and GOES-West, five AVHRR satellites (NOAA and METOP) and MODIS Aqua/Terra. NESDIS' Satellite Analysis Branch (SAB) analysts utilize the HMS to analyze and quality control the automated fire detections from each of the sensors and create the fire/smoke products to enable the users to mitigate disasters and environmental hazards. The new HMS design eliminates the inefficiencies and increases the accuracy of the fire/smoke analysis. The new system has the capability to display higher resolution data available from VIIRS while maintaining individual pixel integrity which improves the representation of fire size. This will benefit the input to smoke forecast models and may possibly be useful as input for fire spread models. An analysis of all VIIRS Active Fire (AF) locations compared to the operational HMS fire analysis for all of 2015 over North America will be presented that will provide an estimate of the impact of this new data set. Results will be presented for regional and seasonal impact. The new system also provides greater analysis control of layers and display properties and will allow for the display of all GOES images, even when in Rapid Scan Operations (RSO) mode. To enhance the efficiency and improve the accuracy of the fire and smoke product, the display of the new HMS eliminates the sector boundaries to display full analysis domain (North and Central America, Caribbean and Hawaii) and has functionality to edit plumes on a finer scale. In the presentation we will highlight the new features of the updated HMS.

Action potentials drive body wall muscle contractions in Caenorhabditis elegans

PubMed Central

Gao, Shangbang; Zhen, Mei

2011-01-01

The sinusoidal locomotion exhibited by Caenorhabditis elegans predicts a tight regulation of contractions and relaxations of its body wall muscles. Vertebrate skeletal muscle contractions are driven by voltage-gated sodium channel–dependent action potentials. How coordinated motor outputs are regulated in C. elegans, which does not have voltage-gated sodium channels, remains unknown. Here, we show that C. elegans body wall muscles fire all-or-none, calcium-dependent action potentials that are driven by the L-type voltage-gated calcium and Kv1 voltage-dependent potassium channels. We further demonstrate that the excitatory and inhibitory motoneuron activities regulate the frequency of action potentials to coordinate muscle contraction and relaxation, respectively. This study provides direct evidence for the dual-modulatory model of the C. elegans motor circuit; moreover, it reveals a mode of motor control in which muscle cells integrate graded inputs of the nervous system and respond with all-or-none electrical signals. PMID:21248227

Modern problems of thermodynamics

NASA Astrophysics Data System (ADS)

Novikov, I. I.

2012-12-01

The role of energy and methods of its saving for the development of human society and life are analyzed. The importance of future use of space energy flows and energy of water and air oceans is emphasized. The authors consider the idea of the unit for production of electric energy and pure substances using sodium chloride which reserves are limitless on the planet. Looking retrospectively at the development of power engineering from the elementary fire to modern electric power station, we see that the used method of heat production, namely by direct interaction of fuel and oxidizer, is the simplest. However, it may be possible to combust coal, i.e., carbon in salt melt, for instance, sodium chloride that would be more rational and efficient. If the stated problems are solved positively, we would master all energy properties of the substance; and this is the main problem of thermodynamics being one of the sciences on energy.

Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability

NASA Astrophysics Data System (ADS)

Paul, Jodi R.; Dewoskin, Daniel; McMeekin, Laura J.; Cowell, Rita M.; Forger, Daniel B.; Gamble, Karen L.

2016-11-01

How neurons encode intracellular biochemical signalling cascades into electrical signals is not fully understood. Neurons in the central circadian clock in mammals provide a model system to investigate electrical encoding of biochemical timing signals. Here, using experimental and modelling approaches, we show how the activation of glycogen synthase kinase 3 (GSK3) contributes to neuronal excitability through regulation of the persistent sodium current (INaP). INaP exhibits a day/night difference in peak magnitude and is regulated by GSK3. Using mathematical modelling, we predict and confirm that GSK3 activation of INaP affects the action potential afterhyperpolarization, which increases the spontaneous firing rate without affecting the resting membrane potential. Together, these results demonstrate a crucial link between the molecular circadian clock and electrical activity, providing examples of kinase regulation of electrical activity and the propagation of intracellular signals in neuronal networks.

The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms

PubMed Central

Duménieu, Maël; Oulé, Marie; Kreutz, Michael R.; Lopez-Rojas, Jeffrey

2017-01-01

Neurons are highly polarized cells with apparent functional and morphological differences between dendrites and axon. A critical determinant for the molecular and functional identity of axonal and dendritic segments is the restricted expression of voltage-gated ion channels (VGCs). Several studies show an uneven distribution of ion channels and their differential regulation within dendrites and axons, which is a prerequisite for an appropriate integration of synaptic inputs and the generation of adequate action potential (AP) firing patterns. This review article will focus on the signaling pathways leading to segmented expression of voltage-gated potassium and sodium ion channels at the neuronal plasma membrane and the regulatory mechanisms ensuring segregated functions. We will also discuss the relevance of proper ion channel targeting for neuronal physiology and how alterations in polarized distribution contribute to neuronal pathology. PMID:28484374

Upregulation of the sodium channel NaVβ4 subunit and its contributions to mechanical hypersensitivity and neuronal hyperexcitability in a rat model of radicular pain induced by local DRG inflammation

PubMed Central

Xie, Wenrui; Tan, Zhi-Yong; Barbosa, Cindy; Strong, Judith A.; Cummins, Theodore R.; Zhang, Jun-Ming

2016-01-01

High frequency spontaneous firing in myelinated sensory neurons plays a key role in initiating pain behaviors in several different models, including the radicular pain model in which the rat lumbar dorsal root ganglia (DRG) are locally inflamed. The sodium channel isoform NaV1.6 contributes to pain behaviors and spontaneous activity in this model. Among all the isoforms in adult DRG, NaV1.6 is the main carrier of TTX-sensitive resurgent Na currents that allow high-frequency firing. Resurgent currents flow after a depolarization or action potential, as a blocking particle exits the pore. In most neurons the regulatory β4 subunit is potentially the endogenous blocker. We used in vivo siRNA mediated knockdown of NaVβ4 to examine its role in the DRG inflammation model. NaVβ4 but not control siRNA almost completely blocked mechanical hypersensitivity induced by DRG inflammation. Microelectrode recordings in isolated whole DRGs showed that NaVβ4 siRNA blocked the inflammation-induced increase in spontaneous activity of Aβ neurons, and reduced repetitive firing and other measures of excitability. NaVβ4 was preferentially expressed in larger diameter cells; DRG inflammation increased its expression and this was reversed by NaVβ4 siRNA, based on immunohistochemistry and Western blotting. NaVβ4 siRNA also reduced immunohistochemical NaV1.6 expression. Patch clamp recordings of TTX-sensitive Na currents in acutely cultured medium diameter DRG neurons showed that DRG inflammation increased transient and especially resurgent current; effects blocked by NaVβ4 siRNA. NaVβ4 may represent a more specific target for pain conditions that depend on myelinated neurons expressing NaV1.6. PMID:26785322

Production and efficiency of large wildland fire suppression effort: A stochastic frontier analysis.

PubMed

Katuwal, Hari; Calkin, David E; Hand, Michael S

2016-01-15

This study examines the production and efficiency of wildland fire suppression effort. We estimate the effectiveness of suppression resource inputs to produce controlled fire lines that contain large wildland fires using stochastic frontier analysis. Determinants of inefficiency are identified and the effects of these determinants on the daily production of controlled fire line are examined. Results indicate that the use of bulldozers and fire engines increase the production of controlled fire line, while firefighter crews do not tend to contribute to controlled fire line production. Production of controlled fire line is more efficient if it occurs along natural or built breaks, such as rivers and roads, and within areas previously burned by wildfires. However, results also indicate that productivity and efficiency of the controlled fire line are sensitive to weather, landscape and fire characteristics. Copyright © 2015 Elsevier Ltd. All rights reserved.

The analysis of factors of management of safety of critical information infrastructure with use of dynamic models

NASA Astrophysics Data System (ADS)

Trostyansky, S. N.; Kalach, A. V.; Lavlinsky, V. V.; Lankin, O. V.

2018-03-01

Based on the analysis of the dynamic model of panel data by region, including fire statistics for surveillance sites and statistics of a set of regional socio-economic indicators, as well as the time of rapid response of the state fire service to fires, the probability of fires in the surveillance sites and the risk of human death in The result of such fires from the values of the corresponding indicators for the previous year, a set of regional social-economics factors, as well as regional indicators time rapid response of the state fire service in the fire. The results obtained are consistent with the results of the application to the fire risks of the model of a rational offender. Estimation of the economic equivalent of human life from data on surveillance objects for Russia, calculated on the basis of the analysis of the presented dynamic model of fire risks, correctly agrees with the known literary data. The results obtained on the basis of the econometric approach to fire risks allow us to forecast fire risks at the supervisory sites in the regions of Russia and to develop management solutions to minimize such risks.

Fine structuration of low-temperature co-fired ceramic (LTCC) microreactors.

PubMed

Jiang, Bo; Haber, Julien; Renken, Albert; Muralt, Paul; Kiwi-Minsker, Lioubov; Maeder, Thomas

2015-01-21

The development of microreactors that operate under harsh conditions is always of great interest for many applications. Here we present a microfabrication process based on low-temperature co-fired ceramic (LTCC) technology for producing microreactors which are able to perform chemical processes at elevated temperature (>400 °C) and against concentrated harsh chemicals such as sodium hydroxide, sulfuric acid and hydrochloric acid. Various micro-scale cavities and/or fluidic channels were successfully fabricated in these microreactors using a set of combined and optimized LTCC manufacturing processes. Among them, it has been found that laser micromachining and multi-step low-pressure lamination are particularly critical to the fabrication and quality of these microreactors. Demonstration of LTCC microreactors with various embedded fluidic structures is illustrated with a number of examples, including micro-mixers for studies of exothermic reactions, multiple-injection microreactors for ionone production, and high-temperature microreactors for portable hydrogen generation.

High Temperature Corrosion Problem of Boiler Components in presence of Sulfur and Alkali based Fuels

NASA Astrophysics Data System (ADS)

Ghosh, Debashis; Mitra, Swapan Kumar

2011-04-01

Material degradation and ageing is of particular concern for fossil fuel fired power plant components. New techniques/approaches have been explored in recent years for Residual Life assessment of aged components and material degradation due to different damage mechanism like creep, fatigue, corrosion and erosion etc. Apart from the creep, the high temperature corrosion problem in a fossil fuel fired boiler is a matter of great concern if the fuel contains sulfur, chlorine sodium, potassium and vanadium etc. This paper discusses the material degradation due to high temperature corrosion in different critical components of boiler like water wall, superheater and reheater tubes and also remedial measures to avoid the premature failure. This paper also high lights the Residual Life Assessment (RLA) methodology of the components based on high temperature fireside corrosion. of different critical components of boiler.

Production and efficiency of large wildland fire suppression effort: A stochastic frontier analysis

Treesearch

Hari Katuwal; Dave Calkin; Michael S. Hand

2016-01-01

This study examines the production and efficiency of wildland fire suppression effort. We estimate the effectiveness of suppression resource inputs to produce controlled fire lines that contain large wildland fires using stochastic frontier analysis. Determinants of inefficiency are identified and the effects of these determinants on the daily production of...

A method for ensemble wildland fire simulation

Treesearch

Mark A. Finney; Isaac C. Grenfell; Charles W. McHugh; Robert C. Seli; Diane Trethewey; Richard D. Stratton; Stuart Brittain

2011-01-01

An ensemble simulation system that accounts for uncertainty in long-range weather conditions and two-dimensional wildland fire spread is described. Fuel moisture is expressed based on the energy release component, a US fire danger rating index, and its variation throughout the fire season is modeled using time series analysis of historical weather data. This analysis...

Long-term impact of wildfire on soils exposed to different fire severities. A case study in Cadiretes Massif (NE Iberian Peninsula).

PubMed

Francos, Marcos; Úbeda, Xavier; Pereira, Paulo; Alcañiz, Meritxell

2018-02-15

Wildfires affect ecosystems depending on the fire regime. Long-term studies are needed to understand the ecological role played by fire, especially as regards its impact on soils. The aim of this study is to monitor the long-term effects (18years) of a wildfire on soil properties in two areas affected by low and high fire severity regimes. The properties studied were total nitrogen (TN), total carbon (TC), C/N ratio, soil organic matter (SOM) and extractable calcium (Ca), magnesium (Mg), sodium (Na) and potassium (K). The study was carried out in three phases: short- (immediately after the wildfire), medium- (seven years after the wildfire) and long-term (18years after the wildfire). The results showed that in both fire regimes TN decreased with time, TC and SOM were significantly lower in the burned plots than they were in the control in the medium- and long-terms. C/N ratio was significantly lower at short-term in low wildfire severity area. Extractable Ca and Mg were significantly higher in control plot than in the burned plots in the medium-term. In the long-term, extractable Ca and Mg were significantly lower in the area exposed to a high severity burning. No differences were identified in the case of extractable Na between plots on any of the sampling dates, while extractable K was significantly higher in the plot exposed to low wildfire than it was in the control. Some restoration measures may be required after the wildfire, especially in areas affected by high severity burning, to avoid the long-term impacts on the essential soil nutrients of TC, SOM, extractable Ca and Mg. This long-term nutrient depletion is attributable to vegetation removal, erosion, leaching and post-fire vegetation consumption. Soils clearly need more time to recover from wildfire disturbance, especially in areas affected by high severity fire regimes. Copyright © 2017 Elsevier B.V. All rights reserved.

Assessment of dermal hazard from acid burns with fire retardant garments in a full-size simulation of an engulfment flash fire.

PubMed

Mackay, Christopher E; Vivanco, Stephanie N; Yeboah, George; Vercellone, Jeff

2016-09-01

There have been concerns that fire-derived acid gases could aggravate thermal burns for individuals wearing synthetic flame retardant garments. A comparative risk assessment was performed on three commercial flame retardant materials with regard to relative hazards associated with acidic combustion gases to skin during a full engulfment flash fire event. The tests were performed in accordance with ASTM F1930 and ISO 13506: Standard Test Method for Evaluation of Flame Resistant Clothing for Protection against Fire Simulations Using an Instrumented Manikin. Three fire retardant textiles were tested: an FR treated cotton/nylon blend, a low Protex(®) modacrylic blend, and a medium Protex(®) modacrylic blend. The materials, in the form of whole body coveralls, were subjected to propane-fired flash conditions of 84kW/m(2) in a full sized simulator for a duration of either 3 or 4s. Ion traps consisting of wetted sodium carbonate-impregnated cellulose in Teflon holders were placed on the chest and back both above and under the standard undergarments. The ion traps remained in position from the time of ignition until 5min post ignition. Results indicated that acid deposition did increase with modacrylic content from 0.9μmol/cm(2) for the cotton/nylon, to 12μmol/cm(2) for the medium modacrylic blend. The source of the acidity was dominated by hydrogen chloride. Discoloration was inversely proportional to the amount of acid collected on the traps. A risk assessment was performed on the potential adverse impact of acid gases on both the skin and open wounds. The results indicated that the deposition and dissolution of the acid gases in surficial fluid media (perspiration and blood plasma) resulted in an increase in acidity, but not sufficient to induce irritation/skin corrosion or to cause necrosis in open third degree burns. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Synaptic and intrinsic activation of GABAergic neurons in the cardiorespiratory brainstem network.

PubMed

Frank, Julie G; Mendelowitz, David

2012-01-01

GABAergic pathways in the brainstem play an essential role in respiratory rhythmogenesis and interactions between the respiratory and cardiovascular neuronal control networks. However, little is known about the identity and function of these GABAergic inhibitory neurons and what determines their activity. In this study we have identified a population of GABAergic neurons in the ventrolateral medulla that receive increased excitatory post-synaptic potentials during inspiration, but also have spontaneous firing in the absence of synaptic input. Using transgenic mice that express GFP under the control of the Gad1 (GAD67) gene promoter, we determined that this population of GABAergic neurons is in close apposition to cardioinhibitory parasympathetic cardiac neurons in the nucleus ambiguus (NA). These neurons fire in synchronization with inspiratory activity. Although they receive excitatory glutamatergic synaptic inputs during inspiration, this excitatory neurotransmission was not altered by blocking nicotinic receptors, and many of these GABAergic neurons continue to fire after synaptic blockade. The spontaneous firing in these GABAergic neurons was not altered by the voltage-gated calcium channel blocker cadmium chloride that blocks both neurotransmission to these neurons and voltage-gated Ca(2+) currents, but spontaneous firing was diminished by riluzole, demonstrating a role of persistent sodium channels in the spontaneous firing in these cardiorespiratory GABAergic neurons that possess a pacemaker phenotype. The spontaneously firing GABAergic neurons identified in this study that increase their activity during inspiration would support respiratory rhythm generation if they acted primarily to inhibit post-inspiratory neurons and thereby release inspiration neurons to increase their activity. This population of inspiratory-modulated GABAergic neurons could also play a role in inhibiting neurons that are most active during expiration and provide a framework for respiratory sinus arrhythmia as there is an increase in heart rate during inspiration that occurs via inhibition of premotor parasympathetic cardioinhibitory neurons in the NA during inspiration.

Effect of wood smoke exposure on vascular function and thrombus formation in healthy fire fighters.

PubMed

Hunter, Amanda L; Unosson, Jon; Bosson, Jenny A; Langrish, Jeremy P; Pourazar, Jamshid; Raftis, Jennifer B; Miller, Mark R; Lucking, Andrew J; Boman, Christoffer; Nyström, Robin; Donaldson, Kenneth; Flapan, Andrew D; Shah, Anoop S V; Pung, Louis; Sadiktsis, Ioannis; Masala, Silvia; Westerholm, Roger; Sandström, Thomas; Blomberg, Anders; Newby, David E; Mills, Nicholas L

2014-12-09

Myocardial infarction is the leading cause of death in fire fighters and has been linked with exposure to air pollution and fire suppression duties. We therefore investigated the effects of wood smoke exposure on vascular vasomotor and fibrinolytic function, and thrombus formation in healthy fire fighters. In a double-blind randomized cross-over study, 16 healthy male fire fighters were exposed to wood smoke (~1 mg/m³ particulate matter concentration) or filtered air for one hour during intermittent exercise. Arterial pressure and stiffness were measured before and immediately after exposure, and forearm blood flow was measured during intra-brachial infusion of endothelium-dependent and -independent vasodilators 4-6 hours after exposure. Thrombus formation was assessed using the ex vivo Badimon chamber at 2 hours, and platelet activation was measured using flow cytometry for up to 24 hours after the exposure. Compared to filtered air, exposure to wood smoke increased blood carboxyhaemoglobin concentrations (1.3% versus 0.8%; P < 0.001), but had no effect on arterial pressure, augmentation index or pulse wave velocity (P > 0.05 for all). Whilst there was a dose-dependent increase in forearm blood flow with each vasodilator (P < 0.01 for all), there were no differences in blood flow responses to acetylcholine, sodium nitroprusside or verapamil between exposures (P > 0.05 for all). Following exposure to wood smoke, vasodilatation to bradykinin increased (P = 0.003), but there was no effect on bradykinin-induced tissue-plasminogen activator release, thrombus area or markers of platelet activation (P > 0.05 for all). Wood smoke exposure does not impair vascular vasomotor or fibrinolytic function, or increase thrombus formation in fire fighters. Acute cardiovascular events following fire suppression may be precipitated by exposure to other air pollutants or through other mechanisms, such as strenuous physical exertion and dehydration.

Optimizing prescribed fire allocation for managing fire risk in central Catalonia.

PubMed

Alcasena, Fermín J; Ager, Alan A; Salis, Michele; Day, Michelle A; Vega-Garcia, Cristina

2018-04-15

We used spatial optimization to allocate and prioritize prescribed fire treatments in the fire-prone Bages County, central Catalonia (northeastern Spain). The goal of this study was to identify suitable strategic locations on forest lands for fuel treatments in order to: 1) disrupt major fire movements, 2) reduce ember emissions, and 3) reduce the likelihood of large fires burning into residential communities. We first modeled fire spread, hazard and exposure metrics under historical extreme fire weather conditions, including node influence grid for surface fire pathways, crown fraction burned and fire transmission to residential structures. Then, we performed an optimization analysis on individual planning areas to identify production possibility frontiers for addressing fire exposure and explore alternative prescribed fire treatment configurations. The results revealed strong trade-offs among different fire exposure metrics, showed treatment mosaics that optimize the allocation of prescribed fire, and identified specific opportunities to achieve multiple objectives. Our methods can contribute to improving the efficiency of prescribed fire treatment investments and wildfire management programs aimed at creating fire resilient ecosystems, facilitating safe and efficient fire suppression, and safeguarding rural communities from catastrophic wildfires. The analysis framework can be used to optimally allocate prescribed fire in other fire-prone areas within the Mediterranean region and elsewhere. Copyright © 2017 Elsevier B.V. All rights reserved.

Carbachol induces burst firing of dopamine cells in the ventral tegmental area by promoting calcium entry through L-type channels in the rat

PubMed Central

Zhang, Lei; Liu, Yudan; Chen, Xihua

2005-01-01

Enhanced activity of the central dopamine system has been implicated in many psychiatric disorders including schizophrenia and addiction. Besides terminal mechanisms that boost dopamine levels at the synapse, the cell body of dopamine cells enhances terminal dopamine concentration through encoding action potentials in bursts. This paper presents evidence that burst firing of dopamine cells in the ventral tegmental area was under cholinergic control using nystatin-perforated patch clamp recording from slice preparations. The non-selective cholinergic agonist carbachol excited the majority of recorded neurones, an action that was not affected by blocking glutamate and GABA ionotropic receptors. Twenty per cent of dopamine cells responded to carbachol with robust bursting, an effect mediated by both muscarinic and nicotinic cholinoceptors postsynaptically. Burst firing induced as such was completely dependent on calcium entry as it could be blocked by cadmium and more specifically the L-type blocker nifedipine. In the presence of the sodium channel blocker tetrodotoxin, carbachol induced membrane potential oscillation that had similar kinetics and frequency as burst firing cycles and could also be blocked by cadmium and nifedipine. Direct activation of the L-type channel with Bay K8644 induced strong bursting which could be blocked by nifedipine but not by depleting internal calcium stores. These results indicate that carbachol increases calcium entry into the postsynaptic cell through L-type channels to generate calcium-dependent membrane potential oscillation and burst firing. This could establish the L-type channel as a target for modulating the function of the central dopamine system in disease conditions. PMID:16081481

Prototypic and Arkypallidal Neurons in the Dopamine-Intact External Globus Pallidus

PubMed Central

Abdi, Azzedine; Mallet, Nicolas; Mohamed, Foad Y.; Sharott, Andrew; Dodson, Paul D.; Nakamura, Kouichi C.; Suri, Sana; Avery, Sophie V.; Larvin, Joseph T.; Garas, Farid N.; Garas, Shady N.; Vinciati, Federica; Morin, Stéphanie; Bezard, Erwan

2015-01-01

Studies in dopamine-depleted rats indicate that the external globus pallidus (GPe) contains two main types of GABAergic projection cell; so-called “prototypic” and “arkypallidal” neurons. Here, we used correlative anatomical and electrophysiological approaches in rats to determine whether and how this dichotomous organization applies to the dopamine-intact GPe. Prototypic neurons coexpressed the transcription factors Nkx2-1 and Lhx6, comprised approximately two-thirds of all GPe neurons, and were the major GPe cell type innervating the subthalamic nucleus (STN). In contrast, arkypallidal neurons expressed the transcription factor FoxP2, constituted just over one-fourth of GPe neurons, and innervated the striatum but not STN. In anesthetized dopamine-intact rats, molecularly identified prototypic neurons fired at relatively high rates and with high regularity, regardless of brain state (slow-wave activity or spontaneous activation). On average, arkypallidal neurons fired at lower rates and regularities than prototypic neurons, and the two cell types could be further distinguished by the temporal coupling of their firing to ongoing cortical oscillations. Complementing the activity differences observed in vivo, the autonomous firing of identified arkypallidal neurons in vitro was slower and more variable than that of prototypic neurons, which tallied with arkypallidal neurons displaying lower amplitudes of a “persistent” sodium current important for such pacemaking. Arkypallidal neurons also exhibited weaker driven and rebound firing compared with prototypic neurons. In conclusion, our data support the concept that a dichotomous functional organization, as actioned by arkypallidal and prototypic neurons with specialized molecular, structural, and physiological properties, is fundamental to the operations of the dopamine-intact GPe. PMID:25926446

Thermal Mechanisms of Millimeter Wave Stimulation of Excitable Cells

PubMed Central

Shapiro, Mikhail G.; Priest, Michael F.; Siegel, Peter H.; Bezanilla, Francisco

2013-01-01

Interactions between millimeter waves (MMWs) and biological systems have received increasing attention due to the growing use of MMW radiation in technologies ranging from experimental medical devices to telecommunications and airport security. Studies have shown that MMW exposure alters cellular function, especially in neurons and muscles. However, the biophysical mechanisms underlying such effects are still poorly understood. Due to the high aqueous absorbance of MMW, thermal mechanisms are likely. However, nonthermal mechanisms based on resonance effects have also been postulated. We studied MMW stimulation in a simplified preparation comprising Xenopus laevis oocytes expressing proteins that underlie membrane excitability. Using electrophysiological recordings simultaneously with 60 GHz stimulation, we observed changes in the kinetics and activity levels of voltage-gated potassium and sodium channels and a sodium-potassium pump that are consistent with a thermal mechanism. Furthermore, we showed that MMW stimulation significantly increased the action potential firing rate in oocytes coexpressing voltage-gated sodium and potassium channels, as predicted by thermal terms in the Hodgkin-Huxley model of neurons. Our results suggest that MMW stimulation produces significant thermally mediated effects on excitable cells via basic thermodynamic mechanisms that must be taken into account in the study and use of MMW radiation in biological systems. PMID:23790370

Cost-effective fire management for southern California's chaparral wilderness: an analytical procedure

Treesearch

Chris A. Childers; Douglas D. Piirto

1989-01-01

Fire management has always meant fire suppression to the managers of the chaparral covered southern California National Forests. Today, Forest Service fire management programs must be cost effective, while wilderness fire management objectives are aimed at recreating natural fire regimes. A cost-effectiveness analysis has been developed to compare fire management...

Decision modeling for fire incident analysis

Treesearch

Donald G. MacGregor; Armando González-Cabán

2009-01-01

This paper reports on methods for representing and modeling fire incidents based on concepts and models from the decision and risk sciences. A set of modeling techniques are used to characterize key fire management decision processes and provide a basis for incident analysis. The results of these methods can be used to provide insights into the structure of fire...

Social and economic issues of the Hayman Fire

Treesearch

Brian Kent; Krista Gebert; Sarah McCaffrey; Wade Martin; David Calkin; Ervin Schuster; Ingrid Martin; Holly Wise Bender; Greg Alward; Yoshitaka Kumagai; Patricia J. Cohn; Matt Carroll; Dan Williams; Carol Ekarius

2004-01-01

On June 26, 2002, U.S. Representative Mark Udall wrote the US Forest Service Chief, requesting that the Forest Service conduct an analysis of the Hayman Fire. In response to the Congressman's letter, five teams were established in August, 2002 to analyze various aspects of the Hayman Fire experience. This report describes the Hayman Fire analysis work conducted by...

Mapping burned areas and burn severity patterns across the Mediterranean region

NASA Astrophysics Data System (ADS)

Kalogeropoulos, Christos; Amatulli, Giuseppe; Kempeneers, Pieter; Sedano, Fernando; San Miguel-Ayanz, Jesus; Camia, Andrea

2010-05-01

The Mediterranean region is highly susceptible to wildfires. On average, about 60,000 fires take place in this region every year, burning on average half a million hectares of forests and natural vegetation. Wildfires cause environmental degradation and affect the lives of thousands of people in the region. In order to minimize the consequences of these catastrophic events, fire managers and national authorities need to have in their disposal accurate and updated spatial information concerning the size of the burned area as well as the burn severity patterns. Mapping burned areas and burn severity patterns is necessary to effectively support the decision-making process in what concerns strategic (long-term) planning with the definition of post-fire actions at European and national scales. Although a comprehensive archive of burnt areas exists at the European Forest Fire Information System, the analysis of the severity of the areas affected by forest fires in the region is not yet available. Fire severity is influenced by many variables, including fuel type, topography and meteorological conditions before and during the fire. The analysis of fire severity is essential to determine the socio-economic impact of forest fires, to assess fire impacts, and to determine the need of post-fire rehabilitation measures. Moreover, fire severity is linked to forest fire emissions and determines the rate of recovery of the vegetation after the fire. Satellite imagery can give important insights about the conditions of the live fuel moisture content and can be used to assess changes on vegetation structure and vitality after forest fires. Fire events occurred in Greece, Portugal and Spain during the fire season of 2009 were recorded and analyzed in a GIS environment. The Normalized Difference Vegetation Index (NDVI), the Enhanced Vegetation Index (EVI) and the Normalized Burn Ratio (NBR) were calculated from 8-days composites MODIS/TERRA imagery from March to October 2009. In addition, subtracting a post-fire from a pre-fire image derived index produces a measure of absolute change of the vegetation condition, like the differenced Normalized Burn Ratio index (dNBR). The aim of this study was the assessment of fire severity across diverse ecological and environmental conditions in the Mediterranean region. The specific objectives were: • The analysis of the correlation between the fire severity and local site conditions, including topography, fuel type, land use, land cover. • The analysis of the correlation between fire severity and fire danger conditions during the fire, as estimated by the European Forest Fire Information System. • Assessing the performance of several vegetation indices derived from MODIS imagery in estimating fire severity. • Assessing the permanence of the burnt signal for large fires as an estimate of fire severity.

Remote Sensing of Chaparral Fire Potential: Case Study in Topanga Canyon, California.

DTIC Science & Technology

Remote sensing techniques, especially the use of color infrared aerial photography, provide a useful tool for fire hazard analysis, including interpetive information about fuel volumes, physiognomic plant groupings, the relationships of buildings to both natural and planted vegetation, and fire vulnerability of roofing materials. In addition, the behavior of the September, 1970 Wright Fire in the Topanga study area suggested the validity of the fire potential analysis which had been made prior to that conflagration.

Mexican forest fires and their decadal variations

NASA Astrophysics Data System (ADS)

Velasco Herrera, Graciela

2016-11-01

A high forest fire season of two to three years is regularly observed each decade in Mexican forests. This seems to be related to the presence of the El Niño phenomenon and to the amount of total solar irradiance. In this study, the results of a multi-cross wavelet analysis are reported based on the occurrence of Mexican forest fires, El Niño and the total solar irradiance for the period 1970-2014. The analysis shows that Mexican forest fires and the strongest El Niño phenomena occur mostly around the minima of the solar cycle. This suggests that the total solar irradiance minima provide the appropriate climatological conditions for the occurrence of these forest fires. The next high season for Mexican forest fires could start in the next solar minimum, which will take place between the years 2017 and 2019. A complementary space analysis based on MODIS active fire data for Mexican forest fires from 2005 to 2014 shows that most of these fires occur in cedar and pine forests, on savannas and pasturelands, and in the central jungles of the Atlantic and Pacific coasts.

Scale Dependence of Oak Woodland Historical Fire Intervals: Contrasting the Barrens of Tennessee and Cross Timbers of Oklahoma, USA

Treesearch

Michael C. Stambaugh; Richard P. Guyette; Joseph M. Marschall; Daniel C. Dey

2016-01-01

Characterization of scale dependence of fire intervals could inform interpretations of fire history and improve fire prescriptions that aim to mimic historical fire regime conditions. We quantified the temporal variability in fire regimes and described the spatial dependence of fire intervals through the analysis of multi-century fire scar records (8 study sites, 332...

78 FR 45573 - Compensatory and Alternative Regulatory Measures for Nuclear Power Plant Fire Protection (CARMEN...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-29

... Nuclear Power Plant Fire Protection (CARMEN-FIRE) AGENCY: Nuclear Regulatory Commission. ACTION: Notice of... Nuclear Power Plant Fire Protection (CARMEN-FIRE), Draft Report for Comment.'' DATES: Comments on this... CONTACT: Felix Gonzalez, Fire Research Branch, Division of Risk Analysis, Office of Nuclear Regulatory...

Avifaunal responses to fire in southwestern montane forests along a burn severity gradient

USGS Publications Warehouse

Kotliar, N.B.; Kennedy, P.L.; Ferree, K.

2007-01-01

The effects of burn severity on avian communities are poorly understood, yet this information is crucial to fire management programs. To quantify avian response patterns along a burn severity gradient, we sampled 49 random plots (2001-2002) at the 17 351-ha Cerro Grande Fire (2000) in New Mexico, USA. Additionally, pre-fire avian surveys (1986-1988, 1990) created a unique opportunity to quantify avifaunal changes in 13 pre-fire transects (resampled in 2002) and to compare two designs for analyzing the effects of unplanned disturbances: after-only analysis and before-after comparisons. Distance analysis was used to calculate densities. We analyzed after-only densities for 21 species using gradient analysis, which detected a broad range of responses to increasing burn severity: (I) large significant declines, (II) weak, but significant declines, (III) no significant density changes, (IV) peak densities in low- or moderate-severity patches, (V) weak, but significant increases, and (VI) large significant increases. Overall, 71% of the species included in the after-only gradient analysis exhibited either positive or neutral density responses to fire effects across all or portions of the severity gradient (responses III-VI). We used pre/post pairs analysis to quantify density changes for 15 species using before-after comparisons; spatiotemporal variation in densities was large and confounded fire effects for most species. Only four species demonstrated significant effects of burn severity, and their densities were all higher in burned compared to unburned forests. Pre- and post-fire community similarity was high except in high-severity areas. Species richness was similar pre- and post-fire across all burn severities. Thus, ecosystem restoration programs based on the assumption that recent severe fires in Southwestern ponderosa pine forests have overriding negative ecological effects are not supported by our study of post-fire avian communities. This study illustrates the importance of quantifying burn severity and controlling confounding sources of spatiotemporal variation in studies of fire effects. After-only gradient analysis can be an efficient tool for quantifying fire effects. This analysis can also augment historical data sets that have small samples sizes coupled with high non-process variation, which limits the power of before-after comparisons. ?? 2007 by the Ecological Society of America.

Study on test of coal co-firing for 600MW ultra supercritical boiler with four walls tangential burning

NASA Astrophysics Data System (ADS)

Ying, Wu; Yong-lu, Zhong; Guo-mingi, Yin

2018-06-01

On account of nine commonly used coals in a Jiangxi Power Plant,two kinds of coal were selected to be applied in coal co-firing test through industrial analysis,elementary analysis and thermogravimetric analysis of coal.During the coal co-firing test,two load points were selected,three coal mixtures were prepared.Moreover,under each coal blending scheme, the optimal oxygen content was obtained by oxygen varying test. At last,by measuring the boiler efficiency and coal consumption of power supply in different coal co-firing schemes, the recommended coal co-firing scheme was obtained.

Users Guide for Fire Image Analysis System - Version 5.0: A Tool for Measuring Fire Behavior Characteristics

Treesearch

Carl W. Adkins

1995-01-01

The Fire Image Analysis System is a tool for quantifying flame geometry and relative position at selected points along a spreading line fire. At present, the system requires uniform terrain (constant slope). The system has been used in field and laboratory studies for determining flame length, depth, cross sectional area, and rate of spread.

Forest Fire History... A Computer Method of Data Analysis

Treesearch

Romain M. Meese

1973-01-01

A series of computer programs is available to extract information from the individual Fire Reports (U.S. Forest Service Form 5100-29). The programs use a statistical technique to fit a continuous distribution to a set of sampled data. The goodness-of-fit program is applicable to data other than the fire history. Data summaries illustrate analysis of fire occurrence,...

An Analysis of Stochastic Duels Involving Fixed Rates of Fire

DTIC Science & Technology

The thesis presents an analysis of stochastic duels involving two opposing weapon systems with constant rates of fire. The duel was developed as a...process stochastic duels . The analysis was then extended to the two versus one duel where the three weapon systems were assumed to have fixed rates of fire.

On the characterization of vegetation recovery after fire disturbance using Fisher-Shannon analysis and SPOT/VEGETATION Normalized Difference Vegetation Index (NDVI) time series

NASA Astrophysics Data System (ADS)

Lasaponara, Rosa; Lanorte, Antonio; Lovallo, Michele; Telesca, Luciano

2015-04-01

Time series can fruitfully support fire monitoring and management from statistical analysis of fire occurrence (Tuia et al. 2008) to danger estimation (lasaponara 2005), damage evaluation (Lanorte et al 2014) and post fire recovery (Lanorte et al. 2014). In this paper, the time dynamics of SPOT-VEGETATION Normalized Difference Vegetation Index (NDVI) time series are analyzed by using the statistical approach of the Fisher-Shannon (FS) information plane to assess and monitor vegetation recovery after fire disturbance. Fisher-Shannon information plane analysis allows us to gain insight into the complex structure of a time series to quantify its degree of organization and order. The analysis was carried out using 10-day Maximum Value Composites of NDVI (MVC-NDVI) with a 1 km × 1 km spatial resolution. The investigation was performed on two test sites located in Galizia (North Spain) and Peloponnese (South Greece), selected for the vast fires which occurred during the summer of 2006 and 2007 and for their different vegetation covers made up mainly of low shrubland in Galizia test site and evergreen forest in Peloponnese. Time series of MVC-NDVI have been analyzed before and after the occurrence of the fire events. Results obtained for both the investigated areas clearly pointed out that the dynamics of the pixel time series before the occurrence of the fire is characterized by a larger degree of disorder and uncertainty; while the pixel time series after the occurrence of the fire are featured by a higher degree of organization and order. In particular, regarding the Peloponneso fire, such discrimination is more evident than in the Galizia fire. This suggests a clear possibility to discriminate the different post-fire behaviors and dynamics exhibited by the different vegetation covers. Reference Lanorte A, R Lasaponara, M Lovallo, L Telesca 2014 Fisher-Shannon information plane analysis of SPOT/VEGETATION Normalized Difference Vegetation Index (NDVI) time series to characterize vegetation recovery after fire disturbanceInternational Journal of Applied Earth Observation and Geoinformation 26 441-446 Lanorte A, M Danese, R Lasaponara, B Murgante 2014 Multiscale mapping of burn area and severity using multisensor satellite data and spatial autocorrelation analysis International Journal of Applied Earth Observation and Geoinformation 20, 42-51 Tuia D, F Ratle, R Lasaponara, L Telesca, M Kanevski 2008 Scan statistics analysis of forest fire clusters Communications in Nonlinear Science and Numerical Simulation 13 (8), 1689-1694 Telesca L, R Lasaponara 2006 Pre and post fire behavioral trends revealed in satellite NDVI time series Geophysical Research Letters 33 (14) Lasaponara R 2005 Intercomparison of AVHRR based fire susceptibility indicators for the Mediterranean ecosystems of southern Italy International Journal of Remote Sensing 26 (5), 853-870

Knowledge-Based Systems Approach to Wilderness Fire Management.

NASA Astrophysics Data System (ADS)

Saveland, James M.

The 1988 and 1989 forest fire seasons in the Intermountain West highlight the shortcomings of current fire policy. To fully implement an optimization policy that minimizes the costs and net value change of resources affected by fire, long-range fire severity information is essential, yet lacking. This information is necessary for total mobility of suppression forces, implementing contain and confine suppression strategies, effectively dealing with multiple fire situations, scheduling summer prescribed burning, and wilderness fire management. A knowledge-based system, Delphi, was developed to help provide long-range information. Delphi provides: (1) a narrative of advice on where a fire might spread, if allowed to burn, (2) a summary of recent weather and fire danger information, and (3) a Bayesian analysis of long-range fire danger potential. Uncertainty is inherent in long-range information. Decision theory and judgment research can be used to help understand the heuristics experts use to make decisions under uncertainty, heuristics responsible both for expert performance and bias. Judgment heuristics and resulting bias are examined from a fire management perspective. Signal detection theory and receiver operating curve (ROC) analysis can be used to develop a long-range forecast to improve decisions. ROC analysis mimics some of the heuristics and compensates for some of the bias. Most importantly, ROC analysis displays a continuum of bias from which an optimum operating point can be selected. ROC analysis is especially appropriate for long-range forecasting since (1) the occurrence of possible future events is stated in terms of probability, (2) skill prediction is displayed, (3) inherent trade-offs are displayed, and (4) fire danger is explicitly defined. Statements on the probability of the energy release component of the National Fire Danger Rating System exceeding a critical value later in the fire season can be made early July in the Intermountain West. Delphi was evaluated formally and informally. Continual evaluation and feedback to update knowledge-based systems results in a repository for current knowledge, and a means to devise policy that will augment existing knowledge. Thus, knowledge-based systems can help implement adaptive resource management.

Dopamine Neurons Change the Type of Excitability in Response to Stimuli

PubMed Central

Gutkin, Boris S.; Lapish, Christopher C.; Kuznetsov, Alexey

2016-01-01

The dynamics of neuronal excitability determine the neuron’s response to stimuli, its synchronization and resonance properties and, ultimately, the computations it performs in the brain. We investigated the dynamical mechanisms underlying the excitability type of dopamine (DA) neurons, using a conductance-based biophysical model, and its regulation by intrinsic and synaptic currents. Calibrating the model to reproduce low frequency tonic firing results in N-methyl-D-aspartate (NMDA) excitation balanced by γ-Aminobutyric acid (GABA)-mediated inhibition and leads to type I excitable behavior characterized by a continuous decrease in firing frequency in response to hyperpolarizing currents. Furthermore, we analyzed how excitability type of the DA neuron model is influenced by changes in the intrinsic current composition. A subthreshold sodium current is necessary for a continuous frequency decrease during application of a negative current, and the low-frequency “balanced” state during simultaneous activation of NMDA and GABA receptors. Blocking this current switches the neuron to type II characterized by the abrupt onset of repetitive firing. Enhancing the anomalous rectifier Ih current also switches the excitability to type II. Key characteristics of synaptic conductances that may be observed in vivo also change the type of excitability: a depolarized γ-Aminobutyric acid receptor (GABAR) reversal potential or co-activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) leads to an abrupt frequency drop to zero, which is typical for type II excitability. Coactivation of N-methyl-D-aspartate receptors (NMDARs) together with AMPARs and GABARs shifts the type I/II boundary toward more hyperpolarized GABAR reversal potentials. To better understand how altering each of the aforementioned currents leads to changes in excitability profile of DA neuron, we provide a thorough dynamical analysis. Collectively, these results imply that type I excitability in dopamine neurons might be important for low firing rates and fine-tuning basal dopamine levels, while switching excitability to type II during NMDAR and AMPAR activation may facilitate a transient increase in dopamine concentration, as type II neurons are more amenable to synchronization by mutual excitation. PMID:27930673

Fire and Smoke Model Evaluation Experiment (FASMEE): Modeling gaps and data needs

Treesearch

Yongqiang Liu; Adam Kochanski; Kirk Baker; Ruddy Mell; Rodman Linn; Ronan Paugam; Jan Mandel; Aime Fournier; Mary Ann Jenkins; Scott Goodrick; Gary Achtemeier; Andrew Hudak; Matthew Dickson; Brian Potter; Craig Clements; Shawn Urbanski; Roger Ottmar; Narasimhan Larkin; Timothy Brown; Nancy French; Susan Prichard; Adam Watts; Derek McNamara

2017-01-01

Fire and smoke models are numerical tools for simulating fire behavior, smoke dynamics, and air quality impacts of wildland fires. Fire models are developed based on the fundamental chemistry and physics of combustion and fire spread or statistical analysis of experimental data (Sullivan 2009). They provide information on fire spread and fuel consumption for safe and...

An analysis of wildfire frequency and burned area relationships with human pressure and climate gradients in the context of fire regime

NASA Astrophysics Data System (ADS)

Jiménez-Ruano, Adrián; Rodrigues Mimbrero, Marcos; de la Riva Fernández, Juan

2017-04-01

Understanding fire regime is a crucial step towards achieving a better knowledge of the wildfire phenomenon. This study proposes a method for the analysis of fire regime based on multidimensional scatterplots (MDS). MDS are a visual approach that allows direct comparison among several variables and fire regime features so that we are able to unravel spatial patterns and relationships within the region of analysis. Our analysis is conducted in Spain, one of the most fire-affected areas within the Mediterranean region. Specifically, the Spanish territory has been split into three regions - Northwest, Hinterland and Mediterranean - considered as representative fire regime zones according to MAGRAMA (Spanish Ministry of Agriculture, Environment and Food). The main goal is to identify key relationships between fire frequency and burnt area, two of the most common fire regime features, with socioeconomic activity and climate. In this way we will be able to better characterize fire activity within each fire region. Fire data along the period 1974-2010 was retrieved from the General Statistics Forest Fires database (EGIF). Specifically, fire frequency and burnt area size was examined for each region and fire season (summer and winter). Socioeconomic activity was defined in terms of human pressure on wildlands, i.e. the presence and intensity of anthropogenic activity near wildland or forest areas. Human pressure was built from GIS spatial information about land use (wildland-agriculture and wildland-urban interface) and demographic potential. Climate variables (average maximum temperature and annual precipitation) were extracted from MOTEDAS (Monthly Temperature Dataset of Spain) and MOPREDAS (Monthly Precipitation Dataset of Spain) datasets and later reclassified into ten categories. All these data were resampled to fit the 10x10 Km grid used as spatial reference for fire data. Climate and socioeconomic variables were then explored by means of MDS to find the extent to which fire frequency and burnt areas are controlled by either environmental, human, or both factors. Results reveal a noticeable link between fire frequency and human activity, especially in the Northwest area during winter. On the other hand, in the Hinterland and Mediterranean regions, human and climate factors 'work' together in terms of their relationship with fire activity, being the concurrence of high human pressure and favourable climate conditions the main driver. In turn, burned area shows a similar behaviour except in the Hinterland region, were fire-affected area depends mostly on climate factors. Overall, we can conclude that the visual analysis of multidimensional scatterplots has proved to be a powerful tool that facilitates characterization and investigation of fire regimes.

The Wildland Fire Decision Support System: Integrating science, technology, and fire management

Treesearch

Morgan Pence; Tom Zimmerman

2011-01-01

Federal agency policy requires documentation and analysis of all wildland fire response decisions. In the past, planning and decision documentation for fires were completed using multiple unconnected processes, yielding many limitations. In response, interagency fire management executives chartered the development of the Wildland Fire Decision Support System (WFDSS)....

Forest fires in the insular Caribbean

Treesearch

A.M.J. Robbins; C.M. Eckelmann; M. Quinones

2008-01-01

This paper presents a summary of the forest fire reports in the insular Caribbean derived from both management reports and an analysis of publicly available Moderate Resolution Imaging Spectrodiometer (MODIS) satellite active fire products from the region. A vast difference between the amount of fires reported by land managers and fire points in the MODIS Fire...

Forest fire spatial pattern analysis in Galicia (NW Spain).

PubMed

Fuentes-Santos, I; Marey-Pérez, M F; González-Manteiga, W

2013-10-15

Knowledge of fire behaviour is of key importance in forest management. In the present study, we analysed the spatial structure of forest fire with spatial point pattern analysis and inference techniques recently developed in the Spatstat package of R. Wildfires have been the primary threat to Galician forests in recent years. The district of Fonsagrada-Ancares is one of the most seriously affected by fire in the region and, therefore, the central focus of the study. Our main goal was to determine the spatial distribution of ignition points to model and predict fire occurrence. These data are of great value in establishing enhanced fire prevention and fire fighting plans. We found that the spatial distribution of wildfires is not random and that fire occurrence may depend on ownership conflicts. We also found positive interaction between small and large fires and spatial independence between wildfires in consecutive years. Copyright © 2013 Elsevier Ltd. All rights reserved.

Social and economic issues of the Hayman Fire

Treesearch

Brian Kent; Krista Gebert; Sarah McCaffrey; Wade Martin; David Calkin; Ervin Schuster; Ingrid Martin; Holly Wise Bender; Greg Alward; Yoshitaka Kumagai; Patricia J. Cohn; Matt Carroll; Daniel Williams; Carol Ekarius

2003-01-01

On June 26, 2002, U.S. Representative Mark Udall wrote the US Forest Service Chief, requesting that the Forest Service conduct an analysis of the Hayman Fire. In response to the Congressman’s letter, five teams were established in August, 2002 to analyze various aspects of the Hayman Fire experience. This report describes the Hayman Fire analysis work conducted by the...

Spatial patterns in vegetation fires in the Indian region.

PubMed

Vadrevu, Krishna Prasad; Badarinath, K V S; Anuradha, Eaturu

2008-12-01

In this study, we used fire count datasets derived from Along Track Scanning Radiometer (ATSR) satellite to characterize spatial patterns in fire occurrences across highly diverse geographical, vegetation and topographic gradients in the Indian region. For characterizing the spatial patterns of fire occurrences, observed fire point patterns were tested against the hypothesis of a complete spatial random (CSR) pattern using three different techniques, the quadrat analysis, nearest neighbor analysis and Ripley's K function. Hierarchical nearest neighboring technique was used to depict the 'hotspots' of fire incidents. Of the different states, highest fire counts were recorded in Madhya Pradesh (14.77%) followed by Gujarat (10.86%), Maharastra (9.92%), Mizoram (7.66%), Jharkhand (6.41%), etc. With respect to the vegetation categories, highest number of fires were recorded in agricultural regions (40.26%) followed by tropical moist deciduous vegetation (12.72), dry deciduous vegetation (11.40%), abandoned slash and burn secondary forests (9.04%), tropical montane forests (8.07%) followed by others. Analysis of fire counts based on elevation and slope range suggested that maximum number of fires occurred in low and medium elevation types and in very low to low-slope categories. Results from three different spatial techniques for spatial pattern suggested clustered pattern in fire events compared to CSR. Most importantly, results from Ripley's K statistic suggested that fire events are highly clustered at a lag-distance of 125 miles. Hierarchical nearest neighboring clustering technique identified significant clusters of fire 'hotspots' in different states in northeast and central India. The implications of these results in fire management and mitigation were discussed. Also, this study highlights the potential of spatial point pattern statistics in environmental monitoring and assessment studies with special reference to fire events in the Indian region.

Analysis of weather condition influencing fire regime in Italy

NASA Astrophysics Data System (ADS)

Bacciu, Valentina; Masala, Francesco; Salis, Michele; Sirca, Costantino; Spano, Donatella

2014-05-01

Fires have a crucial role within Mediterranean ecosystems, with both negative and positive impacts on all biosphere components and with reverberations on different scales. Fire determines the landscape structure and plant composition, but it is also the cause of enormous economic and ecological damages, beside the loss of human life. In addition, several authors are in agreement suggesting that, during the past decades, changes on fire patterns have occurred, especially in terms of fire-prone areas expansion and fire season lengthening. Climate and weather are two of the main controlling agents, directly and indirectly, of fire regime influencing vegetation productivity, causing water stress, igniting fires through lightning, or modulating fire behavior through wind. On the other hand, these relationships could be not warranted in areas where most ignitions are caused by people (Moreno et al. 2009). Specific analyses of the driving forces of fire regime across countries and scales are thus still required in order to better anticipate fire seasons and also to advance our knowledge of future fire regimes. The objective of this work was to improve our knowledge of the relative effects of several weather variables on forest fires in Italy for the period 1985-2008. Meteorological data were obtained through the MARS (Monitoring Agricultural Resources) database, interpolated at 25x25 km scale. Fire data were provided by the JRC (Join Research Center) and the CFVA (Corpo Forestale e di Vigilanza Ambientale, Sardinia). A hierarchical cluster analysis, based on fire and weather data, allowed the identification of six homogeneous areas in terms of fire occurrence and climate (pyro-climatic areas). Two statistical techniques (linear and non-parametric models) were applied in order to assess if inter-annual variability in weather pattern and fire events had a significant trend. Then, through correlation analysis and multi-linear regression modeling, we investigated the influence of weather variables on fire activity across a range of time- and spatial-scales. The analysis revealed a general decrease of both number of fires and burned area, although not everywhere with the same magnitude. Overall, regression models where highly significant (p<0.001), and the explained variance ranged from 36% to 80% for fire number and from 37% to 76% for burned area, depending on pyro-climatic area. Moreover, our results contributed in determining the relative importance of climate variables acting at different timescales as control on intrinsic (i.e. flammability and moisture) and extrinsic (i.e. fuel amount and structure) characteristics of vegetation, thus strongly influencing fire occurrence. The good performance of our models, especially in the most fire affected pyro-climatic areas of Italy, and the better understanding of the main driver of fire variability gained through this work could be of great help for fire management among the different pyro-climatic areas.

Quantitative assessment of building fire risk to life safety.

PubMed

Guanquan, Chu; Jinhua, Sun

2008-06-01

This article presents a quantitative risk assessment framework for evaluating fire risk to life safety. Fire risk is divided into two parts: probability and corresponding consequence of every fire scenario. The time-dependent event tree technique is used to analyze probable fire scenarios based on the effect of fire protection systems on fire spread and smoke movement. To obtain the variation of occurrence probability with time, Markov chain is combined with a time-dependent event tree for stochastic analysis on the occurrence probability of fire scenarios. To obtain consequences of every fire scenario, some uncertainties are considered in the risk analysis process. When calculating the onset time to untenable conditions, a range of fires are designed based on different fire growth rates, after which uncertainty of onset time to untenable conditions can be characterized by probability distribution. When calculating occupant evacuation time, occupant premovement time is considered as a probability distribution. Consequences of a fire scenario can be evaluated according to probability distribution of evacuation time and onset time of untenable conditions. Then, fire risk to life safety can be evaluated based on occurrence probability and consequences of every fire scenario. To express the risk assessment method in detail, a commercial building is presented as a case study. A discussion compares the assessment result of the case study with fire statistics.

The Venus Flytrap Dionaea muscipula Counts Prey-Induced Action Potentials to Induce Sodium Uptake.

PubMed

Böhm, Jennifer; Scherzer, Sönke; Krol, Elzbieta; Kreuzer, Ines; von Meyer, Katharina; Lorey, Christian; Mueller, Thomas D; Shabala, Lana; Monte, Isabel; Solano, Roberto; Al-Rasheid, Khaled A S; Rennenberg, Heinz; Shabala, Sergey; Neher, Erwin; Hedrich, Rainer

2016-02-08

Carnivorous plants, such as the Venus flytrap (Dionaea muscipula), depend on an animal diet when grown in nutrient-poor soils. When an insect visits the trap and tilts the mechanosensors on the inner surface, action potentials (APs) are fired. After a moving object elicits two APs, the trap snaps shut, encaging the victim. Panicking preys repeatedly touch the trigger hairs over the subsequent hours, leading to a hermetically closed trap, which via the gland-based endocrine system is flooded by a prey-decomposing acidic enzyme cocktail. Here, we asked the question as to how many times trigger hairs have to be stimulated (e.g., now many APs are required) for the flytrap to recognize an encaged object as potential food, thus making it worthwhile activating the glands. By applying a series of trigger-hair stimulations, we found that the touch hormone jasmonic acid (JA) signaling pathway is activated after the second stimulus, while more than three APs are required to trigger an expression of genes encoding prey-degrading hydrolases, and that this expression is proportional to the number of mechanical stimulations. A decomposing animal contains a sodium load, and we have found that these sodium ions enter the capture organ via glands. We identified a flytrap sodium channel DmHKT1 as responsible for this sodium acquisition, with the number of transcripts expressed being dependent on the number of mechano-electric stimulations. Hence, the number of APs a victim triggers while trying to break out of the trap identifies the moving prey as a struggling Na(+)-rich animal and nutrition for the plant. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

The Venus Flytrap Dionaea muscipula Counts Prey-Induced Action Potentials to Induce Sodium Uptake

PubMed Central

Böhm, Jennifer; Scherzer, Sönke; Krol, Elzbieta; Kreuzer, Ines; von Meyer, Katharina; Lorey, Christian; Mueller, Thomas D.; Shabala, Lana; Monte, Isabel; Solano, Roberto; Al-Rasheid, Khaled A.S.; Rennenberg, Heinz; Shabala, Sergey; Neher, Erwin; Hedrich, Rainer

2016-01-01

Summary Carnivorous plants, such as the Venus flytrap (Dionaea muscipula), depend on an animal diet when grown in nutrient-poor soils. When an insect visits the trap and tilts the mechanosensors on the inner surface, action potentials (APs) are fired. After a moving object elicits two APs, the trap snaps shut, encaging the victim. Panicking preys repeatedly touch the trigger hairs over the subsequent hours, leading to a hermetically closed trap, which via the gland-based endocrine system is flooded by a prey-decomposing acidic enzyme cocktail. Here, we asked the question as to how many times trigger hairs have to be stimulated (e.g., now many APs are required) for the flytrap to recognize an encaged object as potential food, thus making it worthwhile activating the glands. By applying a series of trigger-hair stimulations, we found that the touch hormone jasmonic acid (JA) signaling pathway is activated after the second stimulus, while more than three APs are required to trigger an expression of genes encoding prey-degrading hydrolases, and that this expression is proportional to the number of mechanical stimulations. A decomposing animal contains a sodium load, and we have found that these sodium ions enter the capture organ via glands. We identified a flytrap sodium channel DmHKT1 as responsible for this sodium acquisition, with the number of transcripts expressed being dependent on the number of mechano-electric stimulations. Hence, the number of APs a victim triggers while trying to break out of the trap identifies the moving prey as a struggling Na+-rich animal and nutrition for the plant. Video Abstract PMID:26804557

10 CFR 50.48 - Fire protection.

Code of Federal Regulations, 2011 CFR

2011-01-01

... suppression systems; and (iii) The means to limit fire damage to structures, systems, or components important...) Standard 805, “Performance-Based Standard for Fire Protection for Light Water Reactor Electric Generating... pressurized-water reactors (PWRs) is not permitted. (iv) Uncertainty analysis. An uncertainty analysis...

10 CFR 50.48 - Fire protection.

Code of Federal Regulations, 2010 CFR

2010-01-01

... suppression systems; and (iii) The means to limit fire damage to structures, systems, or components important...) Standard 805, “Performance-Based Standard for Fire Protection for Light Water Reactor Electric Generating... pressurized-water reactors (PWRs) is not permitted. (iv) Uncertainty analysis. An uncertainty analysis...

Cost-benefit analysis of passive fire protections in road LPG transportation.

PubMed

Paltrinieri, Nicola; Bonvicini, Sarah; Spadoni, Gigliola; Cozzani, Valerio

2012-02-01

The cost-benefit evaluation of passive fire protection adoption in the road transport of liquefied petroleum gas (LPG) was investigated. In a previous study, mathematical simulations of real scale fire scenarios proved the effectiveness of passive fire protections in preventing the "fired" boiling liquid expanding vapor explosion (BLEVE), thus providing a significant risk reduction. In the present study the economical aspects of the adoption of fire protections are analyzed and an approach to cost-benefit analysis (CBA) is proposed. The CBA model is based on the comparison of the risk reduction due to fire protections (expressed in monetary terms by the value of a statistical life) and the cost of the application of fire protections to a fleet of tankers. Different types of fire protections were considered, as well as the possibility to apply protections to the entire fleet or only to a part of it. The application of the proposed model to a real-life case study is presented and discussed. Results demonstrate that the adoption of passive fire protections on road tankers, though not compulsory in Europe, can be economically feasible, thus representing a concrete measure to achieve control of the "major hazard accidents" cited by the European legislation. © 2011 Society for Risk Analysis.

Analysis of Idaho fire service education

NASA Astrophysics Data System (ADS)

Roberts, Walter O.

1999-01-01

Becoming a career fire fighter in the state of Idaho requires specialized knowledge and training. Fire science education at Idaho colleges and universities is available only to people who are affiliated with a fire department. Law enforcement curriculum, on the other hand, is available to any interested persons. A student in law enforcement can attend the Police Officers Standards and Training (POST) academy or participate in classes in one of Idaho's institutions for higher education. There are no fire academies in Idaho. Applicants wanting to become professional fire fighters in Idaho are required to compete with applicants from other states; many of whom have had prior fire education and training. Resident Idaho fire fighter applicants are at a disadvantage when applying for Idaho fire fighting positions. Because of this apparent need, I surveyed the Idaho fire chiefs, using a research instrument I developed in a graduate field research class. I wrote the research instrument to determine the educational needs of the Idaho fire service. The College of Southern Idaho (CSI) and the Idaho Fire Chiefs Association (IFCA) were the recipients of this survey. This report, Analysis of Idaho Fire Service Education, describes that research process from beginning to end.

Detection and analysis of high-temperature events in the BIRD mission

NASA Astrophysics Data System (ADS)

Zhukov, Boris; Briess, Klaus; Lorenz, Eckehard; Oertel, Dieter; Skrbek, Wolfgang

2005-01-01

The primary mission objective of a new small Bi-spectral InfraRed Detection (BIRD) satellite is detection and quantitative analysis of high-temperature events like fires and volcanoes. An absence of saturation in the BIRD infrared channels makes it possible to improve false alarm rejection as well as to retrieve quantitative characteristics of hot targets, including their effective fire temperature, area and the radiative energy release. Examples are given of detection and analysis of wild and coal seam fires, of volcanic activity as well as of oil fires in Iraq. The smallest fires detected by BIRD, which were verified on ground, had an area of 12m2 at daytime and 4m2 at night.

Properties of an intermediate-duration inactivation process of the voltage-gated sodium conductance in rat hippocampal CA1 neurons.

PubMed

French, Christopher R; Zeng, Zhen; Williams, David A; Hill-Yardin, Elisa L; O'Brien, Terence J

2016-02-01

Rapid transmembrane flow of sodium ions produces the depolarizing phase of action potentials (APs) in most excitable tissue through voltage-gated sodium channels (NaV). Macroscopic currents display rapid activation followed by fast inactivation (IF) within milliseconds. Slow inactivation (IS) has been subsequently observed in several preparations including neuronal tissues. IS serves important physiological functions, but the kinetic properties are incompletely characterized, especially the operative timescales. Here we present evidence for an "intermediate inactivation" (II) process in rat hippocampal CA1 neurons with time constants of the order of 100 ms. The half-inactivation potentials (V0.5) of steady-state inactivation curves were hyperpolarized by increasing conditioning pulse duration from 50 to 500 ms and could be described by a sum of Boltzmann relations. II state transitions were observed after opening as well as subthreshold potentials. Entry into II after opening was relatively insensitive to membrane potential, and recovery of II became more rapid at hyperpolarized potentials. Removal of fast inactivation with cytoplasmic papaine revealed time constants of INa decay corresponding to II and IS with long depolarizations. Dynamic clamp revealed attenuation of trains of APs over the 10(2)-ms timescale, suggesting a functional role of II in repetitive firing accommodation. These experimental findings could be reproduced with a five-state Markov model. It is likely that II affects important aspects of hippocampal neuron response and may provide a drug target for sodium channel modulation. Copyright © 2016 the American Physiological Society.

Fire-protection research for energy technology: Fy 80 year end report

NASA Astrophysics Data System (ADS)

Hasegawa, H. K.; Alvares, N. J.; Lipska, A. E.; Ford, H.; Priante, S.; Beason, D. G.

1981-05-01

This continuing research program was initiated in order to advance fire protection strategies for Fusion Energy Experiments (FEE). The program expanded to encompass other forms of energy research. Accomplishments for fiscal year 1980 were: finalization of the fault-free analysis of the Shiva fire management system; development of a second-generation, fire-growth analysis using an alternate model and new LLNL combustion dynamics data; improvements of techniques for chemical smoke aerosol analysis; development and test of a simple method to assess the corrosive potential of smoke aerosols; development of an initial aerosol dilution system; completion of primary small-scale tests for measurements of the dynamics of cable fires; finalization of primary survey format for non-LLNL energy technology facilities; and studies of fire dynamics and aerosol production from electrical insulation and computer tape cassettes.

Comparison of the characteristics of fire and non-fire households in the 2004-2005 survey of fire department-attended and unattended fires.

PubMed

Greene, Michael A

2012-06-01

Comparison of characteristics of fire with non-fire households to determine factors differentially associated with fire households (fire risk factors). National household telephone survey in 2004-2005 by the US Consumer Product Safety Commission with 916 fire households and a comparison sample of 2161 non-fire households. There were an estimated 7.4 million fires (96.6% not reported to fire departments) with 130,000 injuries. Bivariate analysis and multivariate logistic regression analyses to assess differences in household characteristics. Significant factors associated with fire households were renting vs. owning (OR 1.988 p<0.0001); household members under 18 year of age (OR 1.277 p<0.0001); lack of residents over 64 years old (OR 0.552 p=0.0007); and college or higher education (some college OR 1.444 p=0.0360, college graduate OR 1.873, p<0.0001, postgraduate OR 2.156 p<0.0001). Not significant were age of house; race; ethnicity; and income. Number of smokers was borderline significant (OR 1.132 p=0.1019) but was significant in the subset of fire households with non-cooking fires (OR 1.383 p=0.0011). Single family houses were associated with non-fire households in the bivariate analysis but not in the multivariate analyses. Renting, household members under 18 years old and smokers are risk factors for unattended fires, similar to the literature for fatal and injury fires. Differences included household members over 65 years old (associated with non-fire households), college/postgraduate education (associated with fire households) and lack of significance of income. Preventing cooking fires (64% of survey incidents), smoking prevention efforts and fire prevention education for families with young children have the potential for reducing unattended fires and injuries.

Sprinkler System Installer. Occupational Analyses Series.

ERIC Educational Resources Information Center

Chinien, Chris; Boutin, France

This analysis covers tasks performed by a sprinkler system installer, an occupational title some provinces and territories of Canada have also identified as pipefitter--fire protection mechanic specialty; sprinkler and fire protection installer; sprinkler and fire protection systems installer; and sprinkler fitter. A guide to analysis discusses…

A meta-analysis of the fire-oak hypothesis: Does prescribed burning promote oak reproduction in eastern North America

Treesearch

Patrick H. Brose; Daniel C. Dey; Ross J. Phillips; Thomas A. Waldrop

2013-01-01

The fire-oak hypothesis asserts that the current lack of fire is a reason behind the widespread oak (Quercus spp.) regeneration difficulties of eastern North America, and use of prescribed burning can help solve this problem. We performed a meta-analysis on the data from 32 prescribed fire studies conducted in mixed-oak forests to test whether they...

An analysis of aircraft accidents involving fires

NASA Technical Reports Server (NTRS)

Lucha, G. V.; Robertson, M. A.; Schooley, F. A.

1975-01-01

All U. S. Air Carrier accidents between 1963 and 1974 were studied to assess the extent of total personnel and aircraft damage which occurred in accidents and in accidents involving fire. Published accident reports and NTSB investigators' factual backup files were the primary sources of data. Although it was frequently not possible to assess the relative extent of fire-caused damage versus impact damage using the available data, the study established upper and lower bounds for deaths and damage due specifically to fire. In 12 years there were 122 accidents which involved airframe fires. Eighty-seven percent of the fires occurred after impact, and fuel leakage from ruptured tanks or severed lines was the most frequently cited cause. A cost analysis was performed for 300 serious accidents, including 92 serious accidents which involved fire. Personal injury costs were outside the scope of the cost analysis, but data on personnel injury judgements as well as settlements received from the CAB are included for reference.

Climate controls on fire pattern in African and Australian continents

NASA Astrophysics Data System (ADS)

Zubkova, M.; Boschetti, L.; Abatzoglou, J. T.

2017-12-01

Studies have primarily attributed the recent decrease in global fire activity in many savanna and grassland regions as detected by the Global Fire Emission Database (GFEDv4s) to anthropogenic changes such as deforestation and cropland expansion (Andela et al. 2017, van der Werf et al. 2008). These changes have occurred despite increases in fire weather season length (Jolly et al. 2015). Efforts to better resolve retrospective and future changes in fire activity require refining the host of influences on societal and environmental factors on fire activity. In this study, we analyzed how climate variability influences interannual fire activity in Africa and Australia, the two continents most affected by fire and responsible for over half of the global pyrogenic emissions. We expand on the analysis presented in Andela et al. (2017) by using the most recent Collection 6 MODIS MCD64 Burned Area Product and exploring the explanatory power of a broader suite of climate variables that have been previously shown to explain fire variability (Bowman et al. 2017). We examined which climate metrics show a strong interannual relationship with the amount of burned area and fire size accounting for antecedent and in-season atmospheric conditions. Fire characteristics were calculated using the 500m resolution MCD64A1 product (2002-2016); the analysis was conducted at the ecoregion scale, and further stratified by landcover using a broad aggregation (forest, shrublands and grasslands) of the Landcover CCI maps (CCI-LC, 2014); all agricultural areas fires were excluded from the analysis. The results of the analysis improve our knowledge of climate controls on fire dynamics in the most fire-prone places in the world which is critical for statistical fire and vegetation models. Being able to predict the impact of climate on fire activity has a strategic importance in designing future fire management scenarios, help to avoid degradation of biodiversity and ecosystem services and improve our understanding of future ecological problems that we can face due to climate change. Andela et al. 2017. doi: 10.1126/science.aal4108 Bowman et al. 2017. doi:10.1038/s41559-016-0058 CCI-LC. 2014. CCI-LC Product User Guide. UCL-Geomatics, Belgium Lolly et al. 2015. doi:10.1038/ncomms8537 van der Werf et al. 2008. doi:10.1029/2007GB003122

Cross-scale analysis of fire regimes

Treesearch

Donald A. Falk; Carol Miller; Donald McKenzie; Anne E. Black

2007-01-01

Cross-scale spatial and temporal perspectives are important for studying contagious landscape disturbances such as fire, which are controlled by myriad processes operating at different scales. We examine fire regimes in forests of western North America, focusing on how observed patterns of fire frequency change across spatial scales. To quantify changes in fire...

Prediction errors in wildland fire situation analyses.

Treesearch

Geoffrey H. Donovan; Peter Noordijk

2005-01-01

Wildfires consume budgets and put the heat on fire managers to justify and control suppression costs. To determine the appropriate suppression strategy, land managers must conduct a wildland fire situation analysis (WFSA) when:A wildland fire is expected to or does escape initial attack,A wildland fire managed for resource benefits...

Analysis of the moderate resolution imaging spectroradiometer contextual algorithm for small fire detection

Treesearch

W. Wang; J.J. Qu; X. Hao; Y. Liu

2009-01-01

In the southeastern United States, most wildland fires are of low intensity. Asubstantial number of these fires cannot be detected by the MODIS contextual algorithm. Toimprove the accuracy of fire detection for this region, the remote-sensed characteristics ofthese fires have to be systematically...

EPRI/NRC-RES fire human reliability analysis guidelines.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, Stuart R.; Cooper, Susan E.; Najafi, Bijan

2010-03-01

During the 1990s, the Electric Power Research Institute (EPRI) developed methods for fire risk analysis to support its utility members in the preparation of responses to Generic Letter 88-20, Supplement 4, 'Individual Plant Examination - External Events' (IPEEE). This effort produced a Fire Risk Assessment methodology for operations at power that was used by the majority of U.S. nuclear power plants (NPPs) in support of the IPEEE program and several NPPs overseas. Although these methods were acceptable for accomplishing the objectives of the IPEEE, EPRI and the U.S. Nuclear Regulatory Commission (NRC) recognized that they required upgrades to support currentmore » requirements for risk-informed, performance-based (RI/PB) applications. In 2001, EPRI and the USNRC's Office of Nuclear Regulatory Research (RES) embarked on a cooperative project to improve the state-of-the-art in fire risk assessment to support a new risk-informed environment in fire protection. This project produced a consensus document, NUREG/CR-6850 (EPRI 1011989), entitled 'Fire PRA Methodology for Nuclear Power Facilities' which addressed fire risk for at power operations. NUREG/CR-6850 developed high level guidance on the process for identification and inclusion of human failure events (HFEs) into the fire PRA (FPRA), and a methodology for assigning quantitative screening values to these HFEs. It outlined the initial considerations of performance shaping factors (PSFs) and related fire effects that may need to be addressed in developing best-estimate human error probabilities (HEPs). However, NUREG/CR-6850 did not describe a methodology to develop best-estimate HEPs given the PSFs and the fire-related effects. In 2007, EPRI and RES embarked on another cooperative project to develop explicit guidance for estimating HEPs for human failure events under fire generated conditions, building upon existing human reliability analysis (HRA) methods. This document provides a methodology and guidance for conducting a fire HRA. This process includes identification and definition of post-fire human failure events, qualitative analysis, quantification, recovery, dependency, and uncertainty. This document provides three approaches to quantification: screening, scoping, and detailed HRA. Screening is based on the guidance in NUREG/CR-6850, with some additional guidance for scenarios with long time windows. Scoping is a new approach to quantification developed specifically to support the iterative nature of fire PRA quantification. Scoping is intended to provide less conservative HEPs than screening, but requires fewer resources than a detailed HRA analysis. For detailed HRA quantification, guidance has been developed on how to apply existing methods to assess post-fire fire HEPs.« less

Fire-climate interactions in the Selway-Bitterroot Wilderness area

Treesearch

Kurt F. Kipfmueller; Thomas W. Swetnam

2000-01-01

Tree-ring reconstructed summer drought was examined in relation to the occurrence of 15 fires in the Selway-Bitterroot Wilderness Area (SBW). The ten largest fire years between 1880 and 1995 were selected from historical fire atlas data; five additional fire years were selected from a fire history completed in a subalpine forest within the SBW. Results of the analysis...

Field procedures for verification and adjustment of fire behavior predictions

Treesearch

Richard C. Rothermel; George C. Rinehart

1983-01-01

The problem of verifying predictions of fire behavior, primarily rate of spread, is discussed in terms of the fire situation for which predictions are made, and the type of fire where data are to be collected. Procedures for collecting data and performing analysis are presented for both readily accessible fires where data should be complete, and for inaccessible fires...

Formulation and performance test of palm-based foaming agent concentrate for fire extinguisher application

NASA Astrophysics Data System (ADS)

Rivai, M.; Hambali, E.; Suryani, A.; Fitria, R.; Firmansyah, S.; Pramuhadi, G.

2018-03-01

The utilization of foaming agent for fire extinguisher application improves the efficiency of water as a fire extinguishing agent, lowers surface tension, and acts as a foaming agent. The formed foam cools the fire down and covers the burned material to avoid it from further contact with oxygen which may reignite the fire. This study aimed to produce and assess the performance of foaming agent concentrate from palm oil as a fire extinguisher agent. In the performance test, measurements were taken on foam stability, foaming ability, surface tension, interfacial tension, viscosity, contact angle, density, and specific gravity. The formulation was conducted by using the best produced potassium palmitate, potassium methyl ester, and sodium lauric combined with diluents, chelating agent, and other additives at various composition comparisons. The produced foaming agent concentrate was found to be in a rather paste and liquid form with viscosity of 2.34 – 253 cP. It was also found that the resulted foaming agent concentrate dissolved in water at the concentration rate of 1% had a foam stability level of 30-91%, foaming ability of 288 – 503%, surface tension of 19.68 – 25.05 dyne/cm, interfacial tension of 0.54 – 4,20 dyne/cm, viscosity of 1.00 – 1.05 cP, contact angles of 53.75 – 63.79° at 0 minute and 11.84 – 22.42 ° at minute 10, density of 0.99586 – 0.99612 g/cm3, and a specific gravity of 1.00021 – 1.00046. Based on foam stability, foaming ability, and surface tension parameters, it was concluded that NF5 and NF17 were the best formulas.Compared to the other formulas, NF5 formula had the best droplet diameter (minimum 0.14 mm) and droplet density (maximum 3056 droplets/cm2).

Initial segment Kv2.2 channels mediate a slow delayed rectifier and maintain high frequency action potential firing in medial nucleus of the trapezoid body neurons

PubMed Central

Johnston, Jamie; Griffin, Sarah J; Baker, Claire; Skrzypiec, Anna; Chernova, Tatanya; Forsythe, Ian D

2008-01-01

The medial nucleus of the trapezoid body (MNTB) is specialized for high frequency firing by expression of Kv3 channels, which minimize action potential (AP) duration, and Kv1 channels, which suppress multiple AP firing, during each calyceal giant EPSC. However, the outward K+ current in MNTB neurons is dominated by another unidentified delayed rectifier. It has slow kinetics and a peak conductance of ∼37 nS; it is half-activated at −9.2 ± 2.1 mV and half-inactivated at −35.9 ± 1.5 mV. It is blocked by several non-specific potassium channel antagonists including quinine (100 μm) and high concentrations of extracellular tetraethylammonium (TEA; IC50 = 11.8 mm), but no specific antagonists were found. These characteristics are similar to recombinant Kv2-mediated currents. Quantitative RT-PCR showed that Kv2.2 mRNA was much more prevalent than Kv2.1 in the MNTB. A Kv2.2 antibody showed specific staining and Western blots confirmed that it recognized a protein ∼110 kDa which was absent in brainstem tissue from a Kv2.2 knockout mouse. Confocal imaging showed that Kv2.2 was highly expressed in axon initial segments of MNTB neurons. In the absence of a specific antagonist, Hodgkin–Huxley modelling of voltage-gated conductances showed that Kv2.2 has a minor role during single APs (due to its slow activation) but assists recovery of voltage-gated sodium channels (Nav) from inactivation by hyperpolarizing interspike potentials during repetitive AP firing. Current-clamp recordings during high frequency firing and characterization of Nav inactivation confirmed this hypothesis. We conclude that Kv2.2-containing channels have a distinctive initial segment location and crucial function in maintaining AP amplitude by regulating the interspike potential during high frequency firing. PMID:18511484

Are High-Severity Fires Burning at Much Higher Rates Recently than Historically in Dry-Forest Landscapes of the Western USA?

PubMed

Baker, William L

2015-01-01

Dry forests at low elevations in temperate-zone mountains are commonly hypothesized to be at risk of exceptional rates of severe fire from climatic change and land-use effects. Their setting is fire-prone, they have been altered by land-uses, and fire severity may be increasing. However, where fires were excluded, increased fire could also be hypothesized as restorative of historical fire. These competing hypotheses are not well tested, as reference data prior to widespread land-use expansion were insufficient. Moreover, fire-climate projections were lacking for these forests. Here, I used new reference data and records of high-severity fire from 1984-2012 across all dry forests (25.5 million ha) of the western USA to test these hypotheses. I also approximated projected effects of climatic change on high-severity fire in dry forests by applying existing projections. This analysis showed the rate of recent high-severity fire in dry forests is within the range of historical rates, or is too low, overall across dry forests and individually in 42 of 43 analysis regions. Significant upward trends were lacking overall from 1984-2012 for area burned and fraction burned at high severity. Upward trends in area burned at high severity were found in only 4 of 43 analysis regions. Projections for A.D. 2046-2065 showed high-severity fire would generally be still operating at, or have been restored to historical rates, although high projections suggest high-severity fire rotations that are too short could ensue in 6 of 43 regions. Programs to generally reduce fire severity in dry forests are not supported and have significant adverse ecological impacts, including reducing habitat for native species dependent on early-successional burned patches and decreasing landscape heterogeneity that confers resilience to climatic change. Some adverse ecological effects of high-severity fires are concerns. Managers and communities can improve our ability to live with high-severity fire in dry forests.

Forest fires in Missouri.

Treesearch

Donald A. Haines; William A. Main; John S. Crosby

1973-01-01

Describes factors that contribute to forest fires on two of the State of Missouri's Protection Districts and the Clark National Forest. Includes an analysis of fire cause, annual distribution, weather, and activity by day of week; also discusses multiple-fire day.

Fire in the Brazilian Amazon: A Spatially Explicit Model for Policy Impact Analysis

NASA Technical Reports Server (NTRS)

Arima, Eugenio Y.; Simmons, Cynthia S.; Walker, Robert T.; Cochrane, Mark A.

2007-01-01

This article implements a spatially explicit model to estimate the probability of forest and agricultural fires in the Brazilian Amazon. We innovate by using variables that reflect farmgate prices of beef and soy, and also provide a conceptual model of managed and unmanaged fires in order to simulate the impact of road paving, cattle exports, and conservation area designation on the occurrence of fire. Our analysis shows that fire is positively correlated with the price of beef and soy, and that the creation of new conservation units may offset the negative environmental impacts caused by the increasing number of fire events associated with early stages of frontier development.

Operating room fires: a closed claims analysis.

PubMed

Mehta, Sonya P; Bhananker, Sanjay M; Posner, Karen L; Domino, Karen B

2013-05-01

To assess patterns of injury and liability associated with operating room (OR) fires, closed malpractice claims in the American Society of Anesthesiologists Closed Claims Database since 1985 were reviewed. All claims related to fires in the OR were compared with nonfire-related surgical anesthesia claims. An analysis of fire-related claims was performed to identify causative factors. There were 103 OR fire claims (1.9% of 5,297 surgical claims). Electrocautery was the ignition source in 90% of fire claims. OR fire claims more frequently involved older outpatients compared with other surgical anesthesia claims (P < 0.01). Payments to patients were more often made in fire claims (P < 0.01), but payment amounts were lower (median $120,166) compared to nonfire surgical claims (median $250,000, P < 0.01). Electrocautery-induced fires (n = 93) increased over time (P < 0.01) to 4.4% claims between 2000 and 2009. Most (85%) electrocautery fires occurred during head, neck, or upper chest procedures (high-fire-risk procedures). Oxygen served as the oxidizer in 95% of electrocautery-induced OR fires (84% with open delivery system). Most electrocautery-induced fires (n = 75, 81%) occurred during monitored anesthesia care. Oxygen was administered via an open delivery system in all high-risk procedures during monitored anesthesia care. In contrast, alcohol-containing prep solutions and volatile compounds were present in only 15% of OR fires during monitored anesthesia care. Electrocautery-induced fires during monitored anesthesia care were the most common cause of OR fires claims. Recognition of the fire triad (oxidizer, fuel, and ignition source), particularly the critical role of supplemental oxygen by an open delivery system during use of the electrocautery, is crucial to prevent OR fires. Continuing education and communication among OR personnel along with fire prevention protocols in high-fire-risk procedures may reduce the occurrence of OR fires.

The Redesigned Hazard Mapping System (HMS) for Fire and Smoke Analysis

NASA Astrophysics Data System (ADS)

Ruminski, M.; Cheng, Z.; Salemi, T.

2017-12-01

The HMS thru November 2016 incorporated a wide variety of satellite data for use in fire and smoke detection, including 30 minute interval GOES-East and GOES-West, five AVHRR satellites (NOAA and METOP) and MODIS Aqua/Terra. NESDIS' Satellite Analysis Branch (SAB) analysts utilize the HMS to analyze and quality control the automated fire detections from each of the sensors and create the fire/smoke products to enable the users to mitigate disasters and environmental hazards. The new HMS design eliminates the inefficiencies and increases the accuracy of the fire/smoke analysis. The new system has the capability to display higher resolution data available from VIIRS and other future sensors while maintaining individual pixel integrity which improves the representation of fire size. This benefits the input to smoke forecast models and may possibly be useful as input for fire spread models. The new system also provides greater analysis control of layers and display properties and allows for the display of all GOES images, even when in Rapid Scan Operations (RSO) mode. To enhance the efficiency and improve the accuracy of the fire and smoke product, the new HMS eliminates the sector boundaries that the old HMS used as part of the GUI and now displays the full analysis domain (North and Central America, Caribbean and Hawaii). There is also now the functionality to edit smoke plumes on a finer scale. In the presentation we will highlight the new features of the updated HMS.

Sodium channel diversity in the vestibular ganglion: NaV1.5, NaV1.8, and tetrodotoxin-sensitive currents

PubMed Central

2016-01-01

Firing patterns differ between subpopulations of vestibular primary afferent neurons. The role of sodium (NaV) channels in this diversity has not been investigated because NaV currents in rodent vestibular ganglion neurons (VGNs) were reported to be homogeneous, with the voltage dependence and tetrodotoxin (TTX) sensitivity of most neuronal NaV channels. RT-PCR experiments, however, indicated expression of diverse NaV channel subunits in the vestibular ganglion, motivating a closer look. Whole cell recordings from acutely dissociated postnatal VGNs confirmed that nearly all neurons expressed NaV currents that are TTX-sensitive and have activation midpoints between −30 and −40 mV. In addition, however, many VGNs expressed one of two other NaV currents. Some VGNs had a small current with properties consistent with NaV1.5 channels: low TTX sensitivity, sensitivity to divalent cation block, and a relatively negative voltage range, and some VGNs showed NaV1.5-like immunoreactivity. Other VGNs had a current with the properties of NaV1.8 channels: high TTX resistance, slow time course, and a relatively depolarized voltage range. In two NaV1.8 reporter lines, subsets of VGNs were labeled. VGNs with NaV1.8-like TTX-resistant current also differed from other VGNs in the voltage dependence of their TTX-sensitive currents and in the voltage threshold for spiking and action potential shape. Regulated expression of NaV channels in primary afferent neurons is likely to selectively affect firing properties that contribute to the encoding of vestibular stimuli. PMID:26936982

Fire, climate and vegetation linkages in the Bolivian Chiquitano seasonally dry tropical forest.

PubMed

Power, M J; Whitney, B S; Mayle, F E; Neves, D M; de Boer, E J; Maclean, K S

2016-06-05

South American seasonally dry tropical forests (SDTFs) are critically endangered, with only a small proportion of their original distribution remaining. This paper presents a 12 000 year reconstruction of climate change, fire and vegetation dynamics in the Bolivian Chiquitano SDTF, based upon pollen and charcoal analysis, to examine the resilience of this ecosystem to drought and fire. Our analysis demonstrates a complex relationship between climate, fire and floristic composition over multi-millennial time scales, and reveals that moisture variability is the dominant control upon community turnover in this ecosystem. Maximum drought during the Early Holocene, consistent with regional drought reconstructions, correlates with a period of significant fire activity between 8000 and 7000 cal yr BP which resulted in a decrease in SDTF diversity. As fire activity declined but severe regional droughts persisted through the Middle Holocene, SDTFs, including Anadenanthera and Astronium, became firmly established in the Bolivian lowlands. The trend of decreasing fire activity during the last two millennia promotes the idea among forest ecologists that SDTFs are threatened by fire. Our analysis shows that the Chiquitano seasonally dry biome has been more resilient to Holocene changes in climate and fire regime than previously assumed, but raises questions over whether this resilience will continue in the future under increased temperatures and drought coupled with a higher frequency anthropogenic fire regime.This article is part of the themed issue 'The interaction of fire and mankind'. © 2016 The Author(s).

Fire, climate and vegetation linkages in the Bolivian Chiquitano seasonally dry tropical forest

PubMed Central

Power, M. J.; Whitney, B. S.; Mayle, F. E.; Neves, D. M.; de Boer, E. J.; Maclean, K. S.

2016-01-01

South American seasonally dry tropical forests (SDTFs) are critically endangered, with only a small proportion of their original distribution remaining. This paper presents a 12 000 year reconstruction of climate change, fire and vegetation dynamics in the Bolivian Chiquitano SDTF, based upon pollen and charcoal analysis, to examine the resilience of this ecosystem to drought and fire. Our analysis demonstrates a complex relationship between climate, fire and floristic composition over multi-millennial time scales, and reveals that moisture variability is the dominant control upon community turnover in this ecosystem. Maximum drought during the Early Holocene, consistent with regional drought reconstructions, correlates with a period of significant fire activity between 8000 and 7000 cal yr BP which resulted in a decrease in SDTF diversity. As fire activity declined but severe regional droughts persisted through the Middle Holocene, SDTFs, including Anadenanthera and Astronium, became firmly established in the Bolivian lowlands. The trend of decreasing fire activity during the last two millennia promotes the idea among forest ecologists that SDTFs are threatened by fire. Our analysis shows that the Chiquitano seasonally dry biome has been more resilient to Holocene changes in climate and fire regime than previously assumed, but raises questions over whether this resilience will continue in the future under increased temperatures and drought coupled with a higher frequency anthropogenic fire regime. This article is part of the themed issue ‘The interaction of fire and mankind’. PMID:27216522

Determination of Realistic Fire Scenarios in Spacecraft

NASA Technical Reports Server (NTRS)

Dietrich, Daniel L.; Ruff, Gary A.; Urban, David

2013-01-01

This paper expands on previous work that examined how large a fire a crew member could successfully survive and extinguish in the confines of a spacecraft. The hazards to the crew and equipment during an accidental fire include excessive pressure rise resulting in a catastrophic rupture of the vehicle skin, excessive temperatures that burn or incapacitate the crew (due to hyperthermia), carbon dioxide build-up or accumulation of other combustion products (e.g. carbon monoxide). The previous work introduced a simplified model that treated the fire primarily as a source of heat and combustion products and sink for oxygen prescribed (input to the model) based on terrestrial standards. The model further treated the spacecraft as a closed system with no capability to vent to the vacuum of space. The model in the present work extends this analysis to more realistically treat the pressure relief system(s) of the spacecraft, include more combustion products (e.g. HF) in the analysis and attempt to predict the fire spread and limiting fire size (based on knowledge of terrestrial fires and the known characteristics of microgravity fires) rather than prescribe them in the analysis. Including the characteristics of vehicle pressure relief systems has a dramatic mitigating effect by eliminating vehicle overpressure for all but very large fires and reducing average gas-phase temperatures.

Fire Risk and Residential Development: A GIS Analysis

Treesearch

Jennifer L. Rechel; James B. Davis; Ted K. Bradshaw

1992-01-01

Population growth is rapid in rural areas in California. This growth into the wildland-urban interface makes fire protection and suppression more difficult. Fire managers have opportunities to reduce fire danger by improving housing development patterns; however, the overall density and placement of houses is usually set by criteria other than fire danger. By...

Using a stochastic model and cross-scale analysis to evaluate controls on historical low-severity fire regimes

Treesearch

Maureen C. Kennedy; Donald McKenzie

2010-01-01

Fire-scarred trees provide a deep temporal record of historical fire activity, but identifying the mechanisms therein that controlled landscape fire patterns is not straightforward. We use a spatially correlated metric for fire co-occurrence between pairs of trees (the Sørensen distance variogram), with output from a neutral model for fire history, to infer the...

Joint Analysis of Bulk Wildfire Characteristics from Multiple Satellite Retrievals

NASA Astrophysics Data System (ADS)

Tang, W.; Arellano, A. F.

2015-12-01

Biomass burning significantly impacts atmospheric composition, as well as regional and global climate. Here, we investigate the spatiotemporal trends in fire characteristics in several major fire regions using combustion signatures observed from space. Our main goals is to identify key relationships between the trends in co-emitted constituents across these regions, as well as linkages to main drivers of change such as meteorology, fire practice, development patterns, and ecosystem feedbacks. Our approach begins with a multi-species analysis of trends in the observed abundance of CO, NO2, and aerosols over these regions and across the time period 2005 to 2014. We use MOPITT multi-spectral CO, OMI tropospheric NO2 column, MODIS AOD, and MODIS FRP retrievals. The long records from these retrievals provide a unique opportunity to study atmospheric composition across the most recent decade. While several studies in the past have reported trends over these regions, most of these studies have focused on a particular constituent. A unique aspect of this work involves understanding co-variations in co-emitted constituents to provide a more comprehensive look at fire characteristics, which are yet to be fully understood. Here, we introduce a derived quantity (called smoke index) to represent bulk fire characteristics (e.g., flaming versus smoldering). The smoke index is calculated as the ratio of the geometric mean of CO and AOD fire enhancements to that of NO2 fire enhancements. Our initial results, which focused on the Amazon region, show that: 1) deforestation fires are dominantly flaming fires while non-deforestation fires are more likely to be dominantly smoldering fires; and 2) droughts have larger influence on non-deforestation (possibly understorey) fires than deforestation fires. Here, we will present an extension of this analysis to other fire regions around the globe (tropical, temperate and boreal fires) and explore other measurements available during this period for comparisons. We will also compare with current fire emission models, such as GFED and FINN, to test the robustness of our findings. We note that this exploratory work provides a unique perspective of fire characteristics that will be useful to improve predictive capability of fire emission and atmospheric models.

Analysis of Flue Gas Desulfurization (FGD) Processes for Potential Use on Army Coal-Fired Boilers

DTIC Science & Technology

1980-09-01

TECHNICAL REPORT N-93 September 1980 ANALYSIS OF FLUE GAS DESULFURIZATION (FGD) PROCESSES FOR POTENTIAL USE ON ARMY COAL-FIRED BOILERS TECHNICAL LIBRARY...REFERENCE: Technical Report N-93, Analysis of Flue Gas Desulfurization (FGD) Ppooesses for Potential Use on Army Coal-Fired Boilers Please take a few...REPORT DOCUMENTATION PAGE 1. REPORT NUMBER CERL-TR-N-93 2. GOVT ACCESSION NO «. TITLE (end Subtitle) ANALYSIS OF FLUE GAS DESULFURIZATION (FGD

Frequency-dependent reliability of spike propagation is function of axonal voltage-gated sodium channels in cerebellar Purkinje cells.

PubMed

Yang, Zhilai; Wang, Jin-Hui

2013-12-01

The spike propagation on nerve axons, like synaptic transmission, is essential to ensure neuronal communication. The secure propagation of sequential spikes toward axonal terminals has been challenged in the neurons with a high firing rate, such as cerebellar Purkinje cells. The shortfall of spike propagation makes some digital spikes disappearing at axonal terminals, such that the elucidation of the mechanisms underlying spike propagation reliability is crucial to find the strategy of preventing loss of neuronal codes. As the spike propagation failure is influenced by the membrane potentials, this process is likely caused by altering the functional status of voltage-gated sodium channels (VGSC). We examined this hypothesis in Purkinje cells by using pair-recordings at their somata and axonal blebs in cerebellar slices. The reliability of spike propagation was deteriorated by elevating spike frequency. The frequency-dependent reliability of spike propagation was attenuated by inactivating VGSCs and improved by removing their inactivation. Thus, the functional status of axonal VGSCs influences the reliability of spike propagation.

Calcium-Activated Potassium Channels at Nodes of Ranvier Secure Axonal Spike Propagation

PubMed Central

Gründemann, Jan; Clark, Beverley A.

2015-01-01

Summary Functional connectivity between brain regions relies on long-range signaling by myelinated axons. This is secured by saltatory action potential propagation that depends fundamentally on sodium channel availability at nodes of Ranvier. Although various potassium channel types have been anatomically localized to myelinated axons in the brain, direct evidence for their functional recruitment in maintaining node excitability is scarce. Cerebellar Purkinje cells provide continuous input to their targets in the cerebellar nuclei, reliably transmitting axonal spikes over a wide range of rates, requiring a constantly available pool of nodal sodium channels. We show that the recruitment of calcium-activated potassium channels (IK, KCa3.1) by local, activity-dependent calcium (Ca2+) influx at nodes of Ranvier via a T-type voltage-gated Ca2+ current provides a powerful mechanism that likely opposes depolarizing block at the nodes and is thus pivotal to securing continuous axonal spike propagation in spontaneously firing Purkinje cells. PMID:26344775

Fire hazard analysis for Plutonium Finishing Plant complex

DOE Office of Scientific and Technical Information (OSTI.GOV)

MCKINNIS, D.L.

1999-02-23

A fire hazards analysis (FHA) was performed for the Plutonium Finishing Plant (PFP) Complex at the Department of Energy (DOE) Hanford site. The scope of the FHA focuses on the nuclear facilities/structures in the Complex. The analysis was conducted in accordance with RLID 5480.7, [DOE Directive RLID 5480.7, 1/17/94] and DOE Order 5480.7A, ''Fire Protection'' [DOE Order 5480.7A, 2/17/93] and addresses each of the sixteen principle elements outlined in paragraph 9.a(3) of the Order. The elements are addressed in terms of the fire protection objectives stated in paragraph 4 of DOE 5480.7A. In addition, the FHA also complies with WHC-CM-4-41,more » Fire Protection Program Manual, Section 3.4 [1994] and WHC-SD-GN-FHA-30001, Rev. 0 [WHC, 1994]. Objectives of the FHA are to determine: (1) the fire hazards that expose the PFP facilities, or that are inherent in the building operations, (2) the adequacy of the fire safety features currently located in the PFP Complex, and (3) the degree of compliance of the facility with specific fire safety provisions in DOE orders, related engineering codes, and standards.« less

Factors Controlling Vegetation Fires in Protected and Non-Protected Areas of Myanmar

PubMed Central

Biswas, Sumalika; Vadrevu, Krishna Prasad; Lwin, Zin Mar; Lasko, Kristofer; Justice, Christopher O.

2015-01-01

Fire is an important disturbance agent in Myanmar impacting several ecosystems. In this study, we quantify the factors impacting vegetation fires in protected and non-protected areas of Myanmar. Satellite datasets in conjunction with biophysical and anthropogenic factors were used in a spatial framework to map the causative factors of fires. Specifically, we used the frequency ratio method to assess the contribution of each causative factor to overall fire susceptibility at a 1km scale. Results suggested the mean fire density in non-protected areas was two times higher than the protected areas. Fire-land cover partition analysis suggested dominant fire occurrences in the savannas (protected areas) and woody savannas (non-protected areas). The five major fire causative factors in protected areas in descending order include population density, land cover, tree cover percent, travel time from nearest city and temperature. In contrast, the causative factors in non-protected areas were population density, tree cover percent, travel time from nearest city, temperature and elevation. The fire susceptibility analysis showed distinct spatial patterns with central Myanmar as a hot spot of vegetation fires. Results from propensity score matching suggested that forests within protected areas have 11% less fires than non-protected areas. Overall, our results identify important causative factors of fire useful to address broad scale fire risk concerns at a landscape scale in Myanmar. PMID:25909632

Factors controlling vegetation fires in protected and non-protected areas of myanmar.

PubMed

Biswas, Sumalika; Vadrevu, Krishna Prasad; Lwin, Zin Mar; Lasko, Kristofer; Justice, Christopher O

2015-01-01

Fire is an important disturbance agent in Myanmar impacting several ecosystems. In this study, we quantify the factors impacting vegetation fires in protected and non-protected areas of Myanmar. Satellite datasets in conjunction with biophysical and anthropogenic factors were used in a spatial framework to map the causative factors of fires. Specifically, we used the frequency ratio method to assess the contribution of each causative factor to overall fire susceptibility at a 1km scale. Results suggested the mean fire density in non-protected areas was two times higher than the protected areas. Fire-land cover partition analysis suggested dominant fire occurrences in the savannas (protected areas) and woody savannas (non-protected areas). The five major fire causative factors in protected areas in descending order include population density, land cover, tree cover percent, travel time from nearest city and temperature. In contrast, the causative factors in non-protected areas were population density, tree cover percent, travel time from nearest city, temperature and elevation. The fire susceptibility analysis showed distinct spatial patterns with central Myanmar as a hot spot of vegetation fires. Results from propensity score matching suggested that forests within protected areas have 11% less fires than non-protected areas. Overall, our results identify important causative factors of fire useful to address broad scale fire risk concerns at a landscape scale in Myanmar.

High sensitivity of spontaneous spike frequency to sodium leak current in a Lymnaea pacemaker neuron.

PubMed

Lu, T Z; Kostelecki, W; Sun, C L F; Dong, N; Pérez Velázquez, J L; Feng, Z-P

2016-12-01

The spontaneous rhythmic firing of action potentials in pacemaker neurons depends on the biophysical properties of voltage-gated ion channels and background leak currents. The background leak current includes a large K + and a small Na + component. We previously reported that a Na + -leak current via U-type channels is required to generate spontaneous action potential firing in the identified respiratory pacemaker neuron, RPeD1, in the freshwater pond snail Lymnaea stagnalis. We further investigated the functional significance of the background Na + current in rhythmic spiking of RPeD1 neurons. Whole-cell patch-clamp recording and computational modeling approaches were carried out in isolated RPeD1 neurons. The whole-cell current of the major ion channel components in RPeD1 neurons were characterized, and a conductance-based computational model of the rhythmic pacemaker activity was simulated with the experimental measurements. We found that the spiking rate is more sensitive to changes in the Na + leak current as compared to the K + leak current, suggesting a robust function of Na + leak current in regulating spontaneous neuronal firing activity. Our study provides new insight into our current understanding of the role of Na + leak current in intrinsic properties of pacemaker neurons. © 2016 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Identifying past fire regimes throughout the Holocene in Ireland using new and established methods of charcoal analysis

NASA Astrophysics Data System (ADS)

Hawthorne, Donna; Mitchell, Fraser J. G.

2016-04-01

Globally, in recent years there has been an increase in the scale, intensity and level of destruction caused by wildfires. This can be seen in Ireland where significant changes in vegetation, land use, agriculture and policy, have promoted an increase in fires in the Irish landscape. This study looks at wildfire throughout the Holocene and draws on lacustrine charcoal records from seven study sites spread across Ireland, to reconstruct the past fire regimes recorded at each site. This work utilises new and accepted methods of fire history reconstruction to provide a recommended analytical procedure for statistical charcoal analysis. Digital charcoal counting was used and fire regime reconstructions carried out via the CharAnalysis programme. To verify this record new techniques are employed; an Ensemble-Member strategy to remove the objectivity associated with parameter selection, a Signal to Noise Index to determine if the charcoal record is appropriate for peak detection, and a charcoal peak screening procedure to validate the identified fire events based on bootstrapped samples. This analysis represents the first study of its kind in Ireland, examining the past record of fire on a multi-site and paleoecological timescale, and will provide a baseline level of data which can be built on in the future when the frequency and intensity of fire is predicted to increase.

Identifying the location of fire refuges in wet forest ecosystems.

PubMed

Berry, Laurence E; Driscoll, Don A; Stein, John A; Blanchard, Wade; Banks, Sam C; Bradstock, Ross A; Lindenmayer, David B

2015-12-01

The increasing frequency of large, high-severity fires threatens the survival of old-growth specialist fauna in fire-prone forests. Within topographically diverse montane forests, areas that experience less severe or fewer fires compared with those prevailing in the landscape may present unique resource opportunities enabling old-growth specialist fauna to survive. Statistical landscape models that identify the extent and distribution of potential fire refuges may assist land managers to incorporate these areas into relevant biodiversity conservation strategies. We used a case study in an Australian wet montane forest to establish how predictive fire simulation models can be interpreted as management tools to identify potential fire refuges. We examined the relationship between the probability of fire refuge occurrence as predicted by an existing fire refuge model and fire severity experienced during a large wildfire. We also examined the extent to which local fire severity was influenced by fire severity in the surrounding landscape. We used a combination of statistical approaches, including generalized linear modeling, variogram analysis, and receiver operating characteristics and area under the curve analysis (ROC AUC). We found that the amount of unburned habitat and the factors influencing the retention and location of fire refuges varied with fire conditions. Under extreme fire conditions, the distribution of fire refuges was limited to only extremely sheltered, fire-resistant regions of the landscape. During extreme fire conditions, fire severity patterns were largely determined by stochastic factors that could not be predicted by the model. When fire conditions were moderate, physical landscape properties appeared to mediate fire severity distribution. Our study demonstrates that land managers can employ predictive landscape fire models to identify the broader climatic and spatial domain within which fire refuges are likely to be present. It is essential that within these envelopes, forest is protected from logging, roads, and other developments so that the ecological processes related to the establishment and subsequent use of fire refuges are maintained.

Heterogeneous firing responses predict diverse couplings to presynaptic activity in mice layer V pyramidal neurons

PubMed Central

2017-01-01

In this study, we present a theoretical framework combining experimental characterizations and analytical calculus to capture the firing rate input-output properties of single neurons in the fluctuation-driven regime. Our framework consists of a two-step procedure to treat independently how the dendritic input translates into somatic fluctuation variables, and how the latter determine action potential firing. We use this framework to investigate the functional impact of the heterogeneity in firing responses found experimentally in young mice layer V pyramidal cells. We first design and calibrate in vitro a simplified morphological model of layer V pyramidal neurons with a dendritic tree following Rall's branching rule. Then, we propose an analytical derivation for the membrane potential fluctuations at the soma as a function of the properties of the synaptic input in dendrites. This mathematical description allows us to easily emulate various forms of synaptic input: either balanced, unbalanced, synchronized, purely proximal or purely distal synaptic activity. We find that those different forms of dendritic input activity lead to various impact on the somatic membrane potential fluctuations properties, thus raising the possibility that individual neurons will differentially couple to specific forms of activity as a result of their different firing response. We indeed found such a heterogeneous coupling between synaptic input and firing response for all types of presynaptic activity. This heterogeneity can be explained by different levels of cellular excitability in the case of the balanced, unbalanced, synchronized and purely distal activity. A notable exception appears for proximal dendritic inputs: increasing the input level can either promote firing response in some cells, or suppress it in some other cells whatever their individual excitability. This behavior can be explained by different sensitivities to the speed of the fluctuations, which was previously associated to different levels of sodium channel inactivation and density. Because local network connectivity rather targets proximal dendrites, our results suggest that this aspect of biophysical heterogeneity might be relevant to neocortical processing by controlling how individual neurons couple to local network activity. PMID:28410418

Emissions from an automobile fire.

PubMed

Lönnermark, Anders; Blomqvist, Per

2006-02-01

The emissions from automobile fires have been investigated. The main gas phase components were analysed in small-scale tests with representative material from an automobile. A more detailed investigation of full-scale simulated automobile fires was also conducted, including the characterisation of gas phase components, particulates and run-off water from extinguishing activities. Three separate full scale fire tests have been characterised: a fire ignited and developed in the engine compartment; a fire ignited inside the coupé, that was extinguished in the early stages; and a similar fire ignited inside the coupé that was allowed to spread until the entire vehicle was involved in the fire. The quantitative analysis of the smoke gases from the full-scale fires showed that emissions with a potentially negative impact on the environment, or chronic toxic effect on humans, were produced in significant quantities. These emissions included HCl, SO2, VOCs (e.g. benzene), PAHs, and PCDDs/PCDFs. Analysis of run-off water indicated that it was severely contaminated, containing elevated levels of both organic compounds and metals. Comparison with data from other vehicle fires found in the literature shows that contamination by lead, copper, zinc, and antimony appears to be significant in water run-off from these types of fires.

Voltage-gated currents in identified rat olfactory receptor neurons.

PubMed

Trombley, P Q; Westbrook, G L

1991-02-01

Whole-cell recording techniques were used to characterize voltage-gated membrane currents in neonatal rat olfactory receptor neurons (ORNs) in cell culture. Mature ORNs were identified in culture by their characteristic bipolar morphology, by retrograde labeling techniques, and by olfactory marker protein (OMP) immunoreactivity. ORNs did not have spontaneous activity, but fired action potentials to depolarizing current pulses. Action potentials were blocked by tetrodotoxin (TTX), which contrasts with the TTX-resistant action potentials in salamander olfactory receptor cells (e.g., Firestein and Werblin, 1987). Prolonged, suprathreshold current pulses evoked only a single action potential; however, repetitive firing up to 35 Hz could be elicited by a series of brief depolarizing pulses. Under voltage clamp, the TTX-sensitive sodium current had activation and inactivation properties similar to other excitable cells. In TTX and 20 mM barium, sustained inward current were evoked by voltage steps positive to -30 mV. This current was blocked by Cd (100 microM) and by nifedipine (IC50 = 368 nM) consistent with L-type calcium channels in other neurons. No T-type calcium current was observed. Voltage steps positive to -20 mV also evoked an outward current that did not inactivate during 100-msec depolarizations. Tail current analysis of this current was consistent with a selective potassium conductance. The outward current was blocked by external tetraethylammonium but was unaffected by Cd or 4-aminopyridine (4-AP) or by removal of external calcium. A transient outward current was not observed. The 3 voltage-dependent conductances in cultured rat ORNs appear to be sufficient for 2 essential functions: action potential generation and transmitter release. As a single odorant-activated channel can trigger an action potential (e.g., Lynch and Barry, 1989), the repetitive firing seen with brief depolarizing pulses suggests that ORNs do not integrate sensory input, but rather act as high-fidelity relays such that each opening of an odorant-activated channel reaches the olfactory bulb glomeruli as an action potential.

Activation properties of trigeminal motoneurons in participants with and without bruxism

PubMed Central

D'Amico, Jessica M.; Yavuz, Ş. Utku; Saraçoğlu, Ahmet; Atiş, Elif Sibel; Türker, Kemal S.

2013-01-01

In animals, sodium- and calcium-mediated persistent inward currents (PICs), which produce long-lasting periods of depolarization under conditions of low synaptic drive, can be activated in trigeminal motoneurons following the application of the monoamine serotonin. Here we examined if PICs are activated in human trigeminal motoneurons during voluntary contractions and under physiological levels of monoaminergic drive (e.g., serotonin and norepinephrine) using a paired motor unit analysis technique. We also examined if PICs activated during voluntary contractions are larger in participants who demonstrate involuntary chewing during sleep (bruxism), which is accompanied by periods of high monoaminergic drive. In control participants, during a slowly increasing and then decreasing isometric contraction, the firing rate of an earlier-recruited masseter motor unit, which served as a measure of synaptic input to a later-recruited test unit, was consistently lower during derecruitment of the test unit compared with at recruitment (ΔF = 4.6 ± 1.5 imp/s). The ΔF, therefore, is a measure of the reduction in synaptic input needed to counteract the depolarization from the PIC to provide an indirect estimate of PIC amplitude. The range of ΔF values measured in the bruxer participants during similar voluntary contractions was the same as in controls, suggesting that abnormally high levels of monoaminergic drive are not continually present in the absence of involuntary motor activity. We also observed a consistent “onion skin effect” during the moderately sized contractions (<20% of maximal), whereby the firing rate of higher threshold motor units discharged at slower rates (by 4–7 imp/s) compared with motor units with relatively lower thresholds. The presence of lower firing rates in the more fatigue-prone, higher threshold trigeminal motoneurons, in addition to the activation of PICs, likely facilitates the activation of the masseter muscle during motor activities such as eating, nonnutritive chewing, clenching, and yawning. PMID:24068753

PKA-induced internalization of slack KNa channels produces dorsal root ganglion neuron hyperexcitability.

PubMed

Nuwer, Megan O; Picchione, Kelly E; Bhattacharjee, Arin

2010-10-20

Inflammatory mediators through the activation of the protein kinase A (PKA) pathway sensitize primary afferent nociceptors to mechanical, thermal, and osmotic stimuli. However, it is unclear which ion conductances are responsible for PKA-induced nociceptor hyperexcitability. We have previously shown the abundant expression of Slack sodium-activated potassium (K(Na)) channels in nociceptive dorsal root ganglion (DRG) neurons. Here we show using cultured DRG neurons, that of the total potassium current, I(K), the K(Na) current is predominantly inhibited by PKA. We demonstrate that PKA modulation of K(Na) channels does not happen at the level of channel gating but arises from the internal trafficking of Slack channels from DRG membranes. Furthermore, we found that knocking down the Slack subunit by RNA interference causes a loss of firing accommodation analogous to that observed during PKA activation. Our data suggest that the change in nociceptive firing occurring during inflammation is the result of PKA-induced Slack channel trafficking.

Statistical analysis of large wildfires

Treesearch

Thomas P. Holmes; Robert J. Jr. Huggett; Anthony L. Westerling

2008-01-01

Large, infrequent wildfires cause dramatic ecological and economic impacts. Consequently, they deserve special attention and analysis. The economic significance of large fires is indicated by the fact that approximately 94 percent of fire suppression costs on U.S. Forest Service land during the period 1980-2002 resulted from a mere 1.4 percent of the fires (Strategic...

Fire in longleaf pine stand management: an economic analysis

Treesearch

Rodney L. Busby; Donald G. Hodges

1999-01-01

A simulation analysis of the economics of using prescribed fire as a forest management tool in the management of longleaf pine (Pinus palustris Mill.) plantations was conducted. A management regime using frequent prescribed fire was compared to management regimes involving fertilization and chemical release, chemical control, and mechanical control. Determining the...

Fuel treatments and fire severity: A meta-analysis

Treesearch

Erik J. Martinson; Philip N. Omi

2013-01-01

We employed meta-analysis and information theory to synthesize findings reported in the literature on the effects of fuel treatments on subsequent fire intensity and severity. Data were compiled from 19 publications that reported observed fire responses from 62 treated versus untreated contrasts. Effect sizes varied widely and the most informative grouping of studies...

Guidance on spatial wildland fire analysis: models, tools, and techniques

Treesearch

Richard D. Stratton

2006-01-01

There is an increasing need for spatial wildland fire analysis in support of incident management, fuel treatment planning, wildland-urban assessment, and land management plan development. However, little guidance has been provided to the field in the form of training, support, or research examples. This paper provides guidance to fire managers, planners, specialists,...

Field modeling of heat transfer in atrium

NASA Astrophysics Data System (ADS)

Nedryshkin, Oleg; Gravit, Marina; Bushuev, Nikolay

2017-10-01

The results of calculating fire risk are an important element in the system of modern fire safety assessment. The article reviews the work on the mathematical modeling of fire in the room. A comparison of different calculation models in the programs of fire risk assessment and fire modeling was performed. The results of full-scale fire tests and fire modeling in the FDS program are presented. The analysis of empirical and theoretical data on fire modeling is made, a conclusion is made about the modeling accuracy in the FDS program.

Electrophysiology of the mammillary complex in vitro. I. Tuberomammillary and lateral mammillary neurons

NASA Technical Reports Server (NTRS)

Llinas, R. R.; Alonso, A.

1992-01-01

1. The electrophysiological properties of the tuberomammillary and lateral mammillary neurons in the guinea pig mammillary body were studied using an in vitro brain slice preparation. 2. Tuberomammillary (n = 79) neurons were recorded mainly ventral to the lateral mammillary body as well as ventromedially to the fornix within the rostral part of the medial mammillary nucleus. Intracellular staining with horseradish peroxidase (n = 9) and Lucifer yellow (n = 3) revealed that these cells have several thick, long, spiny dendrites emerging from large (20-35 microns) fusiform somata. 3. Most tuberomammillary neurons (66%) fired spontaneously at a relatively low frequency (0.5-10 Hz) at the resting membrane potential. The action potentials were broad (2.3 ms) with a prominent Ca(2+)-dependent shoulder on the falling phase. Deep (17.8 mV), long-lasting spike afterhyperpolarizations were largely Ca(2+)-independent. 4. All tuberomammillary neurons recorded displayed pronounced delayed firing when the cells were activated from a potential negative to the resting level. The cells also displayed a delayed return to the baseline at the break of hyperpolarizing pulses applied from a membrane potential level close to firing threshold. Analysis of the voltage- and time dependence of this delayed rectification suggested the presence of a transient outward current similar to the A current (IA). These were not completely blocked by high concentrations of 4-aminopyridine, whereas the delayed onset of firing was always abolished when voltage-dependent Ca2+ conductances were blocked by superfusion with Cd2+. 5. Tuberomammillary neurons also displayed inward rectification in the hyperpolarizing and, primarily, depolarizing range. Block of voltage-gated Na(+)-dependent conductances with tetrodotoxin (TTX) selectively abolished inward rectification in the depolarizing range, indicating the presence of a persistent low-threshold sodium-dependent conductance (gNap). In fact, persistent TTX-sensitive, plateau potentials were always elicited following Ca2+ block with Cd2+ when K+ currents were reduced by superfusion with tetraethylammonium. 6. The gNap in tuberomammillary neurons may subserve the pacemaker current underlying the spontaneous firing of these cells. The large-amplitude spike afterhyperpolarization of these neurons sets the availability of the transient outward rectifier, which, in conjunction with the pacemaker current, establishes the rate at which membrane potential approaches spike threshold. 7. Repetitive firing elicited by direct depolarization enhanced the spike shoulder of tuberomammillary neurons. Spike trains were followed by a Ca(2+)-dependent, apamine-sensitive, slow afterhyperpolarization. 8. Lateral mammillary neurons were morphologically and electrophysiologically different from tuberomammillary neurons. All lateral mammillary neurons neurons recorded (n = 44) were silent at rest (-60 mV).(ABSTRACT TRUNCATED AT 400 WORDS).

Econometric analysis of fire suppression production functions for large wildland fires

Treesearch

Thomas P. Holmes; David E. Calkin

2013-01-01

In this paper, we use operational data collected for large wildland fires to estimate the parameters of economic production functions that relate the rate of fireline construction with the level of fire suppression inputs (handcrews, dozers, engines and helicopters). These parameter estimates are then used to evaluate whether the productivity of fire suppression inputs...

Two centuries of fire in a southwestern Virginia Pinus pungens community

Treesearch

E. K. Sutherland; H. Grissino-Mayer; C. A. Woodhouse; W. W. Covington; S. Horn; L. Huckaby; R. Kerr; J. Kush; M. Moore; T. Plumb

1995-01-01

Fire exclusion in fire-dependent forest communities can alter stand structure and composition. The objective was to construct a fire history of two Pinus pungens Lamb. communities growing in southwestern Virgina. Treering analysis of fire-scarred P. pungens specimens and a tree survey were used to determine species composition and age distributions. From 1798-1944,...

Davis Fire: Fire behavior and fire effects analysis

Treesearch

LaWen T. Hollingsworth

2010-01-01

The Davis Fire presents an interesting example of fire behavior in subalpine fir, partially dead lodgepole pine with multiple age classes, and moist site Douglas-fir vegetation types. This has been summer of moderate temperatures and intermittent moisture that has kept live herbaceous and live woody moistures fairly high and dead fuel moistures at a moderate level....

Analysis of the moderate resolution imaging spectroradiometer contextual algorithm for small fire detection, Journal of Applied Remote Sensing Vol.3

Treesearch

W. Wang; J.J. Qu; X. Hao; Y. Liu

2009-01-01

In the southeastern United States, most wildland fires are of low intensity. A substantial number of these fires cannot be detected by the MODIS contextual algorithm. To improve the accuracy of fire detection for this region, the remote-sensed characteristics of these fires have to be...

Assessment of forest fire impacts and emissions in the European Union based on the European forest fire information system

Treesearch

Paulo Barbosa; Andrea Camia; Jan Kucera; Giorgio Libertá; Ilaria Palumbo; Jesus San-Miguel-Ayanz; Guido Schmuck

2009-01-01

An analysis on the number of forest fires and burned area distribution as retrieved by the European Forest Fire Information System (EFFIS) database is presented. On average, from 2000 to 2005 about...

ASTM standards for fire debris analysis: a review.

PubMed

Stauffer, Eric; Lentini, John J

2003-03-12

The American Society for Testing and Materials (ASTM) recently updated its standards E 1387 and E 1618 for the analysis of fire debris. The changes in the classification of ignitable liquids are presented in this review. Furthermore, a new standard on extraction of fire debris with solid phase microextraction (SPME) was released. Advantages and drawbacks of this technique are presented and discussed. Also, the standard on cleanup by acid stripping has not been reapproved. Fire debris analysts that use the standards should be aware of these changes.

The use of computer models to predict temperature and smoke movement in high bay spaces

NASA Technical Reports Server (NTRS)

Notarianni, Kathy A.; Davis, William D.

1993-01-01

The Building and Fire Research Laboratory (BFRL) was given the opportunity to make measurements during fire calibration tests of the heat detection system in an aircraft hangar with a nominal 30.4 (100 ft) ceiling height near Dallas, TX. Fire gas temperatures resulting from an approximately 8250 kW isopropyl alcohol pool fire were measured above the fire and along the ceiling. The results of the experiments were then compared to predictions from the computer fire models DETACT-QS, FPETOOL, and LAVENT. In section A of the analysis conducted, DETACT-QS AND FPETOOL significantly underpredicted the gas temperature. LAVENT at the position below the ceiling corresponding to maximum temperature and velocity provided better agreement with the data. For large spaces, hot gas transport time and an improved fire plume dynamics model should be incorporated into the computer fire model activation routines. A computational fluid dynamics (CFD) model, HARWELL FLOW3D, was then used to model the hot gas movement in the space. Reasonable agreement was found between the temperatures predicted from the CFD calculations and the temperatures measured in the aircraft hangar. In section B, an existing NASA high bay space was modeled using the CFD model. The NASA space was a clean room, 27.4 m (90 ft) high with forced horizontal laminar flow. The purpose of this analysis is to determine how the existing fire detection devices would respond to various size fires in the space. The analysis was conducted for 32 MW, 400 kW, and 40 kW fires.

Management of Sodium-reduced Meals at Worksite Cafeterias: Perceptions, Practices, Barriers, and Needs among Food Service Personnel.

PubMed

Lee, Jounghee; Park, Sohyun

2016-04-01

The sodium content of meals provided at worksite cafeterias is greater than the sodium content of restaurant meals and home meals. The objective of this study was to assess the relationships between sodium-reduction practices, barriers, and perceptions among food service personnel. We implemented a cross-sectional study by collecting data on perceptions, practices, barriers, and needs regarding sodium-reduced meals at 17 worksite cafeterias in South Korea. We implemented Chi-square tests and analysis of variance for statistical analysis. For post hoc testing, we used Bonferroni tests; when variances were unequal, we used Dunnett T3 tests. This study involved 104 individuals employed at the worksite cafeterias, comprised of 35 men and 69 women. Most of the participants had relatively high levels of perception regarding the importance of sodium reduction (very important, 51.0%; moderately important, 27.9%). Sodium reduction practices were higher, but perceived barriers appeared to be lower in participants with high-level perception of sodium-reduced meal provision. The results of the needs assessment revealed that the participants wanted to have more active education programs targeting the general population. The biggest barriers to providing sodium-reduced meals were use of processed foods and limited methods of sodium-reduced cooking in worksite cafeterias. To make the provision of sodium-reduced meals at worksite cafeterias more successful and sustainable, we suggest implementing more active education programs targeting the general population, developing sodium-reduced cooking methods, and developing sodium-reduced processed foods.

Detection and Characterization of Low Temperature Peat Fires during the 2015 Fire Catastrophe in Indonesia Using a New High-Sensitivity Fire Monitoring Satellite Sensor (FireBird)

PubMed Central

Atwood, Elizabeth C.; Englhart, Sandra; Lorenz, Eckehard; Halle, Winfried; Wiedemann, Werner; Siegert, Florian

2016-01-01

Vast and disastrous fires occurred on Borneo during the 2015 dry season, pushing Indonesia into the top five carbon emitting countries. The region was affected by a very strong El Niño-Southern Oscillation (ENSO) climate phenomenon, on par with the last severe event in 1997/98. Fire dynamics in Central Kalimantan were investigated using an innovative sensor offering higher sensitivity to a wider range of fire intensities at a finer spatial resolution (160 m) than heretofore available. The sensor is onboard the TET-1 satellite, part of the German Aerospace Center (DLR) FireBird mission. TET-1 images (acquired every 2–3 days) from the middle infrared were used to detect fires continuously burning for almost three weeks in the protected peatlands of Sebangau National Park as well as surrounding areas with active logging and oil palm concessions. TET-1 detection capabilities were compared with MODIS active fire detection and Landsat burned area algorithms. Fire dynamics, including fire front propagation speed and area burned, were investigated. We show that TET-1 has improved detection capabilities over MODIS in monitoring low-intensity peatland fire fronts through thick smoke and haze. Analysis of fire dynamics revealed that the largest burned areas resulted from fire front lines started from multiple locations, and the highest propagation speeds were in excess of 500 m/day (all over peat > 2m deep). Fires were found to occur most often in concessions that contained drainage infrastructure but were not cleared prior to the fire season. Benefits of implementing this sensor system to improve current fire management techniques are discussed. Near real-time fire detection together with enhanced fire behavior monitoring capabilities would not only improve firefighting efforts, but also benefit analysis of fire impact on tropical peatlands, greenhouse gas emission estimations as well as mitigation measures to reduce severe fire events in the future. PMID:27486664

Detection and Characterization of Low Temperature Peat Fires during the 2015 Fire Catastrophe in Indonesia Using a New High-Sensitivity Fire Monitoring Satellite Sensor (FireBird).

PubMed

Atwood, Elizabeth C; Englhart, Sandra; Lorenz, Eckehard; Halle, Winfried; Wiedemann, Werner; Siegert, Florian

2016-01-01

Vast and disastrous fires occurred on Borneo during the 2015 dry season, pushing Indonesia into the top five carbon emitting countries. The region was affected by a very strong El Niño-Southern Oscillation (ENSO) climate phenomenon, on par with the last severe event in 1997/98. Fire dynamics in Central Kalimantan were investigated using an innovative sensor offering higher sensitivity to a wider range of fire intensities at a finer spatial resolution (160 m) than heretofore available. The sensor is onboard the TET-1 satellite, part of the German Aerospace Center (DLR) FireBird mission. TET-1 images (acquired every 2-3 days) from the middle infrared were used to detect fires continuously burning for almost three weeks in the protected peatlands of Sebangau National Park as well as surrounding areas with active logging and oil palm concessions. TET-1 detection capabilities were compared with MODIS active fire detection and Landsat burned area algorithms. Fire dynamics, including fire front propagation speed and area burned, were investigated. We show that TET-1 has improved detection capabilities over MODIS in monitoring low-intensity peatland fire fronts through thick smoke and haze. Analysis of fire dynamics revealed that the largest burned areas resulted from fire front lines started from multiple locations, and the highest propagation speeds were in excess of 500 m/day (all over peat > 2m deep). Fires were found to occur most often in concessions that contained drainage infrastructure but were not cleared prior to the fire season. Benefits of implementing this sensor system to improve current fire management techniques are discussed. Near real-time fire detection together with enhanced fire behavior monitoring capabilities would not only improve firefighting efforts, but also benefit analysis of fire impact on tropical peatlands, greenhouse gas emission estimations as well as mitigation measures to reduce severe fire events in the future.

Destructive Physical Analysis of Flight- and Ground-Tested Sodium-Sulfur Cells

NASA Technical Reports Server (NTRS)

Wasz, Margot L.; Carter, Boyd J.; Donet, Charles M.; Baldwin, Richard S.

1999-01-01

Destructive physical analysis (DPA) was used to study the effects of microgravity on the sulfur electrode in sodium-sulfur cells. The cells examined in this work were provided by the Air Force Research Laboratory (AFRL) from their program on sodium-sulfur technology. The Naval Research Laboratory (NRL) provided electrical characterization of the flight-tested and ground-tested cells.

Solubilization of water in water-in-oil microemulsions of kerosene

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andheria, A.P.; Bhagwat, S.S.

1995-04-01

The incorporation of water into fuels formulated as microemulsions can offer several advantages such as fire resistance, increased flash point, and improved air-fuel contact. To this end, phase equilibria of kerosene microemulsions employing ionic and nonionic surfactants such as sodium di-(2-ethylhexyl) sulfosuccinate (AOT), lauryl diethanolamide (LDEA), nonylphenol EO-4.5 (NPEO-4.5), sorbitan monolaurate (Span-20), and cetyltrimethylammonium bromide (CTAB), as well as cosurfactants such as n-pentanol, n-hexanol, and n-heptanol, were studied. The effect of the aromaticity of the oil phase on the solubilization of water was also investigated.

Determination of iridium in mafic rocks by atomic absorption

USGS Publications Warehouse

Grimaldi, F.S.; Schnepfe, M.M.

1970-01-01

Iridium is determined in mineralized mafic rocks by atomic absorption after fire-assay concentration into a gold bead. Interelement interferences in the atomic-absorption determination are removed and Ir sensitivity is increased by buffering the solutions with a mixture of copper and sodium sulphates. Substantial amounts of Ag, Al, Au, Bi, Ca, Cd, Co, Cr, Fe, Ho, Hg, K, La, Mg, Mn, Mo, Ni, Pb, Te, Ti, V, Y, Zn and platinum metals can be tolerated in the atomic-absorption determination. The sensitivity and detection limits are 3.2 and 0.25 ppm of Ir, respectively. ?? 1970.

Field Artillery And Fire Support At The Operational Level: An Analysis Of Operation Desert Storm and Operation Iraqi Freedom

DTIC Science & Technology

2017-05-25

Field Artillery and Fire Support at the Operational Level: An Analysis of Operation Desert Storm and Operation Iraqi Freedom A Monograph...Defense, Washington Headquarters Services, Directorate for Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204...AND SUBTITLE Field Artillery and Fire Support at the Operational Level: An Analysis of Operation Desert Storm and Operation Iraqi Freedom 5a

Dietary Sodium Consumption Predicts Future Blood Pressure and Incident Hypertension in the Japanese Normotensive General Population

PubMed Central

Takase, Hiroyuki; Sugiura, Tomonori; Kimura, Genjiro; Ohte, Nobuyuki; Dohi, Yasuaki

2015-01-01

Background Although there is a close relationship between dietary sodium and hypertension, the concept that persons with relatively high dietary sodium are at increased risk of developing hypertension compared with those with relatively low dietary sodium has not been studied intensively in a cohort. Methods and Results We conducted an observational study to investigate whether dietary sodium intake predicts future blood pressure and the onset of hypertension in the general population. Individual sodium intake was estimated by calculating 24-hour urinary sodium excretion from spot urine in 4523 normotensive participants who visited our hospital for a health checkup. After a baseline examination, they were followed for a median of 1143 days, with the end point being development of hypertension. During the follow-up period, hypertension developed in 1027 participants (22.7%). The risk of developing hypertension was higher in those with higher rather than lower sodium intake (hazard ratio 1.25, 95% CI 1.04 to 1.50). In multivariate Cox proportional hazards regression analysis, baseline sodium intake and the yearly change in sodium intake during the follow-up period (as continuous variables) correlated with the incidence of hypertension. Furthermore, both the yearly increase in sodium intake and baseline sodium intake showed significant correlations with the yearly increase in systolic blood pressure in multivariate regression analysis after adjustment for possible risk factors. Conclusions Both relatively high levels of dietary sodium intake and gradual increases in dietary sodium are associated with future increases in blood pressure and the incidence of hypertension in the Japanese general population. PMID:26224048

Current understanding of the mechanism of action of the antiepileptic drug lacosamide.

PubMed

Rogawski, Michael A; Tofighy, Azita; White, H Steve; Matagne, Alain; Wolff, Christian

2015-02-01

The antiepileptic drug lacosamide [(R)-2-acetamido-N-benzyl-3-methoxypropanamide], a chiral functionalized amino acid, was originally identified by virtue of activity in the mouse and rat maximal electroshock (MES) test. Attention was drawn to lacosamide because of its high oral potency and stereoselectivity. Lacosamide is also active in the 6 Hz seizure model but inactive against clonic seizures in rodents induced by subcutaneous pentylenetetrazol, bicuculline and picrotoxin. It is also ineffective in genetic models of absence epilepsy. At doses greater than those required to confer protection in the MES test, lacosamide inhibits behavioral and electrographic seizures in hippocampal kindled rats. It also effectively terminates seizures in the rat perforant path stimulation status epilepticus model when administered early after the onset of seizures. Lacosamide does not exhibit antiepileptogenic effects in kindling or post-status epilepticus models. The profile of lacosamide in animal seizure and epilepsy models is similar to that of sodium channel blocking antiepileptic drugs, such as phenytoin and carbamazepine. However, unlike these agents, lacosamide does not affect sustained repetitive firing (SRF) on a time scale of hundreds of milliseconds or affect fast inactivation of voltage-gated sodium channels; however, it terminates SRF on a time scale of seconds by an apparent effect on sodium channel slow inactivation. Lacosamide shifts the slow inactivation curve to more hyperpolarized potentials and enhances the maximal fraction of channels that are in the slow inactivated state. Currently, lacosamide is the only known antiepileptic drug in clinical practice that exerts its anticonvulsant activity predominantly by selectively enhancing slow sodium channel inactivation. Copyright © 2014 Elsevier B.V. All rights reserved.

Voltage gating by molecular subunits of Na+ and K+ ion channels: higher-dimensional cubic kinetics, rate constants, and temperature

PubMed Central

2015-01-01

The structural similarity between the primary molecules of voltage-gated Na and K channels (alpha subunits) and activation gating in the Hodgkin-Huxley model is brought into full agreement by increasing the model's sodium kinetics to fourth order (m3 → m4). Both structures then virtually imply activation gating by four independent subprocesses acting in parallel. The kinetics coalesce in four-dimensional (4D) cubic diagrams (16 states, 32 reversible transitions) that show the structure to be highly failure resistant against significant partial loss of gating function. Rate constants, as fitted in phase plot data of retinal ganglion cell excitation, reflect the molecular nature of the gating transitions. Additional dimensions (6D cubic diagrams) accommodate kinetically coupled sodium inactivation and gating processes associated with beta subunits. The gating transitions of coupled sodium inactivation appear to be thermodynamically irreversible; response to dielectric surface charges (capacitive displacement) provides a potential energy source for those transitions and yields highly energy-efficient excitation. A comparison of temperature responses of the squid giant axon (apparently Arrhenius) and mammalian channel gating yields kinetic Q10 = 2.2 for alpha unit gating, whose transitions are rate-limiting at mammalian temperatures; beta unit kinetic Q10 = 14 reproduces the observed non-Arrhenius deviation of mammalian gating at low temperatures; the Q10 of sodium inactivation gating matches the rate-limiting component of activation gating at all temperatures. The model kinetics reproduce the physiologically large frequency range for repetitive firing in ganglion cells and the physiologically observed strong temperature dependence of recovery from inactivation. PMID:25867741

The evaluation of meta-analysis techniques for quantifying prescribed fire effects on fuel loadings.

Treesearch

Karen E. Kopper; Donald McKenzie; David L. Peterson

2009-01-01

Models and effect-size metrics for meta-analysis were compared in four separate meta-analyses quantifying surface fuels after prescribed fires in ponderosa pine (Pinus ponderosa Dougl. ex Laws.) forests of the Western United States. An aggregated data set was compiled from eight published reports that contained data from 65 fire treatment units....

Are High-Severity Fires Burning at Much Higher Rates Recently than Historically in Dry-Forest Landscapes of the Western USA?

PubMed Central

Baker, William L.

2015-01-01

Dry forests at low elevations in temperate-zone mountains are commonly hypothesized to be at risk of exceptional rates of severe fire from climatic change and land-use effects. Their setting is fire-prone, they have been altered by land-uses, and fire severity may be increasing. However, where fires were excluded, increased fire could also be hypothesized as restorative of historical fire. These competing hypotheses are not well tested, as reference data prior to widespread land-use expansion were insufficient. Moreover, fire-climate projections were lacking for these forests. Here, I used new reference data and records of high-severity fire from 1984–2012 across all dry forests (25.5 million ha) of the western USA to test these hypotheses. I also approximated projected effects of climatic change on high-severity fire in dry forests by applying existing projections. This analysis showed the rate of recent high-severity fire in dry forests is within the range of historical rates, or is too low, overall across dry forests and individually in 42 of 43 analysis regions. Significant upward trends were lacking overall from 1984–2012 for area burned and fraction burned at high severity. Upward trends in area burned at high severity were found in only 4 of 43 analysis regions. Projections for A.D. 2046–2065 showed high-severity fire would generally be still operating at, or have been restored to historical rates, although high projections suggest high-severity fire rotations that are too short could ensue in 6 of 43 regions. Programs to generally reduce fire severity in dry forests are not supported and have significant adverse ecological impacts, including reducing habitat for native species dependent on early-successional burned patches and decreasing landscape heterogeneity that confers resilience to climatic change. Some adverse ecological effects of high-severity fires are concerns. Managers and communities can improve our ability to live with high-severity fire in dry forests. PMID:26351850

Modeling post-fire woody carbon dynamics with data from remeasured inventory plots

Treesearch

Bianca N.I. Eskelson; Jeremy Fried; Vicente Monleon

2015-01-01

In California, the Forest Inventory and Analysis (FIA) plots within large fires were visited one year after the fire occurred resulting in a time series of measurements before and after fire. During this additional plot visit, the standard inventory measurements were augmented for these burned plots to assess fire effects. One example of the additional measurements is...

Economic benefits of reducing fire-related sediment in southwestern fire-prone ecosystems

Treesearch

John Loomis; Pete Wohlgemuth; Armando González-Cabán; Don English

2003-01-01

A multiple regression analysis of fire interval and resulting sediment yield (controlling for relief ratio, rainfall, etc.) indicates that reducing the fire interval from the current average 22 years to a prescribed fire interval of 5 years would reduce sediment yield by 2 million cubic meters in the 86.2 square kilometer southern California watershed adjacent to and...

Summaries of BFRL fire research in-house projects and grants, 1993

NASA Astrophysics Data System (ADS)

Jason, Nora H.

1993-09-01

The report describes the fire research projects performed in the Building and Fire Research Laboratory (BFRL) and under its extramural grants program during fiscal year 1993. The BFRL Fire Research Program has directed its efforts under three program thrusts. The in-house priority projects, grants, and externally-funded efforts thus form an integrated, focussed ensemble. The publication is organized along those lines: fire risk and hazard prediction - carbon monoxide prediction, turbulent combustion, soot, engineering analysis, fire hazard assessment, and large fires; fire safety of products and materials - materials combustion, furniture flammability, and wall and ceiling fires; and advanced technologies for fire sensing and control - fire detection and fire suppression. For the convenience of the reader, an alphabetical listing of all grants is contained in Part 2.0.

NOAA/NWS Storm Prediction Center

Science.gov Websites

Thunderstorm/Tornado Watches Mesoscale Discussions Convective Outlooks Thunderstorm Outlook Fire Weather Analysis Sounding Climatology Upper-Air Maps HREF HRRR Browser SREF SREF Plumes Fire Weather Composite Maps Convective Outlook. Critical fire weather conditions are forecast today. See details... Critical fire weather

Wildland Arson as Clandestine Resource Management: A Space-Time Permutation Analysis and Classification of Informal Fire Management Regimes in Georgia, USA

NASA Astrophysics Data System (ADS)

Coughlan, Michael R.

2016-05-01

Forest managers are increasingly recognizing the value of disturbance-based land management techniques such as prescribed burning. Unauthorized, "arson" fires are common in the southeastern United States where a legacy of agrarian cultural heritage persists amidst an increasingly forest-dominated landscape. This paper reexamines unauthorized fire-setting in the state of Georgia, USA from a historical ecology perspective that aims to contribute to historically informed, disturbance-based land management. A space-time permutation analysis is employed to discriminate systematic, management-oriented unauthorized fires from more arbitrary or socially deviant fire-setting behaviors. This paper argues that statistically significant space-time clusters of unauthorized fire occurrence represent informal management regimes linked to the legacy of traditional land management practices. Recent scholarship has pointed out that traditional management has actively promoted sustainable resource use and, in some cases, enhanced biodiversity often through the use of fire. Despite broad-scale displacement of traditional management during the 20th century, informal management practices may locally circumvent more formal and regionally dominant management regimes. Space-time permutation analysis identified 29 statistically significant fire regimes for the state of Georgia. The identified regimes are classified by region and land cover type and their implications for historically informed disturbance-based resource management are discussed.

Research on Influence and Prediction Model of Urban Traffic Link Tunnel curvature on Fire Temperature Based on Pyrosim--SPSS Multiple Regression Analysis

NASA Astrophysics Data System (ADS)

Li, Xiao Ju; Yao, Kun; Dai, Jun Yu; Song, Yun Long

2018-05-01

The underground space, also known as the “fourth dimension” of the city, reflects the efficient use of urban development intensive. Urban traffic link tunnel is a typical underground limited-length space. Due to the geographical location, the special structure of space and the curvature of the tunnel, high-temperature smoke can easily form the phenomenon of “smoke turning” and the fire risk is extremely high. This paper takes an urban traffic link tunnel as an example to focus on the relationship between curvature and the temperature near the fire source, and use the pyrosim built different curvature fire model to analyze the influence of curvature on the temperature of the fire, then using SPSS Multivariate regression analysis simulate curvature of the tunnel and fire temperature data. Finally, a prediction model of urban traffic link tunnel curvature on fire temperature was proposed. The regression model analysis and test show that the curvature is negatively correlated with the tunnel temperature. This model is feasible and can provide a theoretical reference for the urban traffic link tunnel fire protection design and the preparation of the evacuation plan. And also, it provides some reference for other related curved tunnel curvature design and smoke control measures.

Wildland Arson as Clandestine Resource Management: A Space-Time Permutation Analysis and Classification of Informal Fire Management Regimes in Georgia, USA.

PubMed

Coughlan, Michael R

2016-05-01

Forest managers are increasingly recognizing the value of disturbance-based land management techniques such as prescribed burning. Unauthorized, "arson" fires are common in the southeastern United States where a legacy of agrarian cultural heritage persists amidst an increasingly forest-dominated landscape. This paper reexamines unauthorized fire-setting in the state of Georgia, USA from a historical ecology perspective that aims to contribute to historically informed, disturbance-based land management. A space-time permutation analysis is employed to discriminate systematic, management-oriented unauthorized fires from more arbitrary or socially deviant fire-setting behaviors. This paper argues that statistically significant space-time clusters of unauthorized fire occurrence represent informal management regimes linked to the legacy of traditional land management practices. Recent scholarship has pointed out that traditional management has actively promoted sustainable resource use and, in some cases, enhanced biodiversity often through the use of fire. Despite broad-scale displacement of traditional management during the 20th century, informal management practices may locally circumvent more formal and regionally dominant management regimes. Space-time permutation analysis identified 29 statistically significant fire regimes for the state of Georgia. The identified regimes are classified by region and land cover type and their implications for historically informed disturbance-based resource management are discussed.

Sodium Borohydride/Hydrogen Peroxide Fuel Cells For Space Application

NASA Technical Reports Server (NTRS)

Valdez, T. I.; Deelo, M. E.; Narayanan, S. R.

2006-01-01

This viewgraph presentation examines Sodium Borohydride and Hydrogen Peroxide Fuel Cells as they are applied to space applications. The topics include: 1) Motivation; 2) The Sodium Borohydride Fuel Cell; 3) Sodium Borohydride Fuel Cell Test Stands; 4) Fuel Cell Comparisons; 5) MEA Performance; 6) Anode Polarization; and 7) Electrode Analysis. The benefits of hydrogen peroxide as an oxidant and benefits of sodium borohydride as a fuel are also addressed.

Climate effect on forest fire static risk assessment

NASA Astrophysics Data System (ADS)

Bodini, Antonella; Cossu, Antonello; Entrade, Erika; Fiorucci, Paolo; Gaetani, Francesco; Parodi, Ulderica

2010-05-01

The availability of a long data series of fire perimeters combined with a detailed knowledge of topography and land cover allow to understand which are the main features involved in forest fire occurrences and their behaviour. In addition, climate indexes obtained from the analysis of time series with more than 20 years of complete records allow to understand the role of climate on fire regime, both in terms of direct effects on fire behaviour and the effect on vegetation cover. In particular, indices of extreme events have been considered like CDD (maximum number of consecutive dry days) and HWDI (heat wave duration index: maximum period > 5 consecutive days with Tmax >5°C above the 1961-1990 daily Tmax normal), together with the usual indices describing rainfall and temperature regimes. As a matter of fact, based on this information it is possible to develop statistical methods for the objective classification of forest fire static risk at regional scale. Two different case studies are presented in this work: Regione Liguria and Regione Sardegna (Italy). Both regions are in the center of the Mediterranean and are characterized by a high number of fires and burned area. However, the two regions have very different fire regimes. Sardinia is affected by the fire phenomenon only in summer whilst Liguria is affected by fires also in winter, with higher number of fires and larger burned area. In addition, the two region are very different in vegetation cover. The presence of Mediterranean conifers, (Pinus Pinaster, Pinus Nigra, Pinus halepensis) is quite spread in Liguria and is almost absent in Sardinia. What is common in the two regions is the widespread presence of shrub species frequently spread by fire. The analysis in the two regions thus allows in a rather limited area to consider almost all the species and the climate conditions that characterize the Mediterranean region. More than 10000 fire perimeters that burnt about 800 km2 were considered in the analysis. The analysis has been carried out at 20 m spatial resolution. Some important considerations relating to climate and the territorial features that characterize the fire regime in the considered regions contribute to better understand the forest fire phenomena. These results allow to define new strategies for forest fire prevention and management extendable to other geographical areas. This research is part of the project PROTERINA C, funded by the EU under the Italy-France Maritime Programme, aiming at investigating the effects that climate change could have on the environment (fuels).

Spatial controls of occurrence and spread of wildfires in the Missouri Ozark Highlands.

PubMed

Yang, Jian; He, Hong S; Shifley, Stephen R

2008-07-01

Understanding spatial controls on wildfires is important when designing adaptive fire management plans and optimizing fuel treatment locations on a forest landscape. Previous research about this topic focused primarily on spatial controls for fire origin locations alone. Fire spread and behavior were largely overlooked. This paper contrasts the relative importance of biotic, abiotic, and anthropogenic constraints on the spatial pattern of fire occurrence with that on burn probability (i.e., the probability that fire will spread to a particular location). Spatial point pattern analysis and landscape succession fire model (LANDIS) were used to create maps to show the contrast. We quantified spatial controls on both fire occurrence and fire spread in the Midwest Ozark Highlands region, USA. This area exhibits a typical anthropogenic surface fire regime. We found that (1) human accessibility and land ownership were primary limiting factors in shaping clustered fire origin locations; (2) vegetation and topography had a negligible influence on fire occurrence in this anthropogenic regime; (3) burn probability was higher in grassland and open woodland than in closed-canopy forest, even though fire occurrence density was less in these vegetation types; and (4) biotic and abiotic factors were secondary descriptive ingredients for determining the spatial patterns of burn probability. This study demonstrates how fire occurrence and spread interact with landscape patterns to affect the spatial distribution of wildfire risk. The application of spatial point pattern data analysis would also be valuable to researchers working on landscape forest fire models to integrate historical ignition location patterns in fire simulation.

Large forest fires in Canada, 1959-1997

NASA Astrophysics Data System (ADS)

Stocks, B. J.; Mason, J. A.; Todd, J. B.; Bosch, E. M.; Wotton, B. M.; Amiro, B. D.; Flannigan, M. D.; Hirsch, K. G.; Logan, K. A.; Martell, D. L.; Skinner, W. R.

2002-01-01

A Large Fire Database (LFDB), which includes information on fire location, start date, final size, cause, and suppression action, has been developed for all fires larger than 200 ha in area for Canada for the 1959-1997 period. The LFDB represents only 3.1% of the total number of Canadian fires during this period, the remaining 96.9% of fires being suppressed while <200 ha in size, yet accounts for ˜97% of the total area burned, allowing a spatial and temporal analysis of recent Canadian landscape-scale fire impacts. On average ˜2 million ha burned annually in these large fires, although more than 7 million ha burned in some years. Ecozones in the boreal and taiga regions experienced the greatest areas burned, with an average of 0.7% of the forested land burning annually. Lightning fires predominate in northern Canada, accounting for 80% of the total LFDB area burned. Large fires, although small in number, contribute substantially to area burned, most particularly in the boreal and taiga regions. The Canadian fire season runs from late April through August, with most of the area burned occurring in June and July due primarily to lightning fire activity in northern Canada. Close to 50% of the area burned in Canada is the result of fires that are not actioned due to their remote location, low values-at-risk, and efforts to accommodate the natural role of fire in these ecosystems. The LFDB is updated annually and is being expanded back in time to permit a more thorough analysis of long-term trends in Canadian fire activity.

Large forest fires in Canada, 1959-1997

NASA Astrophysics Data System (ADS)

Stocks, B. J.; Mason, J. A.; Todd, J. B.; Bosch, E. M.; Wotton, B. M.; Amiro, B. D.; Flannigan, M. D.; Hirsch, K. G.; Logan, K. A.; Martell, D. L.; Skinner, W. R.

2003-01-01

A Large Fire Database (LFDB), which includes information on fire location, start date, final size, cause, and suppression action, has been developed for all fires larger than 200 ha in area for Canada for the 1959-1997 period. The LFDB represents only 3.1% of the total number of Canadian fires during this period, the remaining 96.9% of fires being suppressed while <200 ha in size, yet accounts for ~97% of the total area burned, allowing a spatial and temporal analysis of recent Canadian landscape-scale fire impacts. On average ~2 million ha burned annually in these large fires, although more than 7 million ha burned in some years. Ecozones in the boreal and taiga regions experienced the greatest areas burned, with an average of 0.7% of the forested land burning annually. Lightning fires predominate in northern Canada, accounting for 80% of the total LFDB area burned. Large fires, although small in number, contribute substantially to area burned, most particularly in the boreal and taiga regions. The Canadian fire season runs from late April through August, with most of the area burned occurring in June and July due primarily to lightning fire activity in northern Canada. Close to 50% of the area burned in Canada is the result of fires that are not actioned due to their remote location, low values-at-risk, and efforts to accommodate the natural role of fire in these ecosystems. The LFDB is updated annually and is being expanded back in time to permit a more thorough analysis of long-term trends in Canadian fire activity.

Manipulating Ratio Spectra for the Spectrophotometric Analysis of Diclofenac Sodium and Pantoprazole Sodium in Laboratory Mixtures and Tablet Formulation

PubMed Central

Bhatt, Nejal M.; Chavada, Vijay D.; Sanyal, Mallika; Shrivastav, Pranav S.

2014-01-01

Objective. Three sensitive, selective, and precise spectrophotometric methods based on manipulation of ratio spectra, have been developed and validated for the determination of diclofenac sodium and pantoprazole sodium. Materials and Methods. The first method is based on ratio spectra peak to peak measurement using the amplitudes at 251 and 318 nm; the second method involves the first derivative of the ratio spectra (Δλ = 4 nm) using the peak amplitudes at 326.0 nm for diclofenac sodium and 337.0 nm for pantoprazole sodium. The third is the method of mean centering of ratio spectra using the values at 318.0 nm for both the analytes. Results. All the three methods were linear over the concentration range of 2.0–24.0 μg/mL for diclofenac sodium and 2.0–20.0 μg/mL for pantoprazole sodium. The methods were validated according to the ICH guidelines and accuracy, precision, repeatability, and robustness are found to be within the acceptable limit. The results of single factor ANOVA analysis indicated that there is no significant difference among the developed methods. Conclusions. The developed methods provided simple resolution of this binary combination from laboratory mixtures and pharmaceutical preparations and can be conveniently adopted for routine quality control analysis. PMID:24701171

Evaluation of short-term changes of hydrological response in mountainous basins of the Vitim Plateau (Russia) after forest fires based on data analysis and hydrological modelling

NASA Astrophysics Data System (ADS)

Semenova, O. M.; Lebedeva, L. S.; Nesterova, N. V.; Vinogradova, T. A.

2015-06-01

Twelve mountainous basins of the Vitim Plateau (Eastern Siberia, Russia) with areas ranging from 967 to 18 200 km2 affected by extensive fires in 2003 (from 13 to 78% of burnt area) were delineated based on MODIS Burned Area Product. The studied area is characterized by scarcity of hydrometeorological observations and complex hydrological processes. Combined analysis of monthly series of flow and precipitation was conducted to detect short-term fire impact on hydrological response of the basins. The idea of basin-analogues which have significant correlation of flow with "burnt" watersheds in stationary (pre-fire) period with the assumption that fire impact produced an outlier of established dependence was applied. Available data allowed for qualitative detection of fire-induced changes at two basins from twelve studied. Summer flow at the Amalat and Vitimkan Rivers (22 and 78% proportion of burnt area in 2003, respectively) increased by 40-50% following the fire.The impact of fire on flow from the other basins was not detectable.The hydrological model Hydrograph was applied to simulate runoff formation processes for stationary pre-fire and non-stationary post-fire conditions. It was assumed that landscape properties changed after the fire suggest a flow increase. These changes were used to assess the model parameters which allowed for better model performance in the post-fire period.

Fire and the endangered Indiana bat

Treesearch

Matthew B. Dickinson; Michael J. Lacki; Daniel R. Cox

2009-01-01

Fire and Indiana bats (Myotis sodalis) have coexisted for millennia in the central hardwoods region, yet past declines in populations of this endangered species, and the imperative of fire use in oak silviculture and ecosystem conservation, call for an analysis of both the risks and opportunities associated with using fires on landscapes in...

Risk of commercial truck fires in the United States : an exploratory data analysis

DOT National Transportation Integrated Search

2012-06-29

Large trucks are involved in only 8 percent of fatal crashes per year, but 17 percent of fatal fires. The scope of the current body of research is limited. Studies have treated truck fires generally as a subset of vehicle fires or in their own right ...

The state of the residential fire fatality problem in Sweden: Epidemiology, risk factors, and event typologies.

PubMed

Jonsson, Anders; Bonander, Carl; Nilson, Finn; Huss, Fredrik

2017-09-01

Residential fires represent the largest category of fatal fires in Sweden. The purpose of this study was to describe the epidemiology of fatal residential fires in Sweden and to identify clusters of events. Data was collected from a database that combines information on fatal fires with data from forensic examinations and the Swedish Cause of Death-register. Mortality rates were calculated for different strata using population statistics and rescue service turnout reports. Cluster analysis was performed using multiple correspondence analysis with agglomerative hierarchical clustering. Male sex, old age, smoking, and alcohol were identified as risk factors, and the most common primary injury diagnosis was exposure to toxic gases. Compared to non-fatal fires, fatal residential fires more often originated in the bedroom, were more often caused by smoking, and were more likely to occur at night. Six clusters were identified. The first two clusters were both smoking-related, but were separated into (1) fatalities that often involved elderly people, usually female, whose clothes were ignited (17% of the sample), (2) middle-aged (45-64years old), (often) intoxicated men, where the fire usually originated in furniture (30%). Other clusters that were identified in the analysis were related to (3) fires caused by technical fault, started in electrical installations in single houses (13%), (4) cooking appliances left on (8%), (5) events with unknown cause, room and object of origin (25%), and (6) deliberately set fires (7%). Fatal residential fires were unevenly distributed in the Swedish population. To further reduce the incidence of fire mortality, specialized prevention efforts that focus on the different needs of each cluster are required. Cooperation between various societal functions, e.g. rescue services, elderly care, psychiatric clinics and other social services, with an application of both human and technological interventions, should reduce residential fire mortality in Sweden. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Progress toward the determination of correct classification rates in fire debris analysis.

PubMed

Waddell, Erin E; Song, Emma T; Rinke, Caitlin N; Williams, Mary R; Sigman, Michael E

2013-07-01

Principal components analysis (PCA), linear discriminant analysis (LDA), and quadratic discriminant analysis (QDA) were used to develop a multistep classification procedure for determining the presence of ignitable liquid residue in fire debris and assigning any ignitable liquid residue present into the classes defined under the American Society for Testing and Materials (ASTM) E 1618-10 standard method. A multistep classification procedure was tested by cross-validation based on model data sets comprised of the time-averaged mass spectra (also referred to as total ion spectra) of commercial ignitable liquids and pyrolysis products from common building materials and household furnishings (referred to simply as substrates). Fire debris samples from laboratory-scale and field test burns were also used to test the model. The optimal model's true-positive rate was 81.3% for cross-validation samples and 70.9% for fire debris samples. The false-positive rate was 9.9% for cross-validation samples and 8.9% for fire debris samples. © 2013 American Academy of Forensic Sciences.

Late Holocene influence of societies on the fire regime in southern Québec temperate forests

NASA Astrophysics Data System (ADS)

Blarquez, Olivier; Talbot, Julie; Paillard, Jordan; Lapointe-Elmrabti, Lyna; Pelletier, Nicolas; Gates St-Pierre, Christian

2018-01-01

Climatic change that occurred during the Holocene is often recognized as the main factor for explaining fire dynamics, while the influence of human societies is less apparent. In eastern North America, human influence on fire regime before European settlement has been debated, mainly because of a paucity of sites and paleoecological techniques that can distinguish human influences unequivocally from climate. We applied a multiproxy analysis to a 12 000-year-old paleoecological sequence from a site in the vicinity of known settlement areas that were occupied over more than 7000 years. From this analysis, we were able detect the human influence on the fire regime before and after European colonization. Fire occurrence and fire return intervals (FRI) were based on analysis of sedimentary charcoals at a high temporal and spatial resolution. Fire occurrence was then compared to vegetation that was reconstructed from pollen analysis, from population densities deduced from archeological site dating, from demographic and technological models, and from climate reconstructed using general circulation models and ice-core isotopes. Holocene mean FRI was short (164 ± 134 years) and associated with small charcoal peaks that were likely indicative of surface fires affecting small areas. After 1500 BP, large vegetation changes and human demographic growth that was demonstrated through increased settlement evidence likely caused the observed FRI lengthening (301 ± 201 years), which occurred without significant changes in climate. Permanent settlement by Europeans in the area around 1800 AD was followed by a substantial demographic increase, leading to the establishment of Gatineau, Hull and Ottawa. This trend was accompanied by a shift in the charcoal record toward anthropogenic particles that were reflective of fossil fuel burning and an apparent absence of wood charcoal that would be indicative of complete fire suppression. An anthropogenic fire regime that was characterized by severe and large fires and long fire-return intervals occurred more than 1000 years ago, concomitant with the spread of native agriculture, which intensified with European colonization over the past two centuries.

Exploring spatial-temporal dynamics of fire regime features in mainland Spain

NASA Astrophysics Data System (ADS)

Jiménez-Ruano, Adrián; Rodrigues Mimbrero, Marcos; de la Riva Fernández, Juan

2017-10-01

This paper explores spatial-temporal dynamics in fire regime features, such as fire frequency, burnt area, large fires and natural- and human-caused fires, as an essential part of fire regime characterization. Changes in fire features are analysed at different spatial - regional and provincial/NUTS3 - levels, together with summer and winter temporal scales, using historical fire data from Spain for the period 1974-2013. Temporal shifts in fire features are investigated by means of change point detection procedures - Pettitt test, AMOC (at most one change), PELT (pruned exact linear time) and BinSeg (binary segmentation) - at a regional level to identify changes in the time series of the features. A trend analysis was conducted using the Mann-Kendall and Sen's slope tests at both the regional and NUTS3 level. Finally, we applied a principal component analysis (PCA) and varimax rotation to trend outputs - mainly Sen's slope values - to summarize overall temporal behaviour and to explore potential links in the evolution of fire features. Our results suggest that most fire features show remarkable shifts between the late 1980s and the first half of the 1990s. Mann-Kendall outputs revealed negative trends in the Mediterranean region. Results from Sen's slope suggest high spatial and intra-annual variability across the study area. Fire activity related to human sources seems to be experiencing an overall decrease in the northwestern provinces, particularly pronounced during summer. Similarly, the Hinterland and the Mediterranean coast are gradually becoming less fire affected. Finally, PCA enabled trends to be synthesized into four main components: winter fire frequency (PC1), summer burnt area (PC2), large fires (PC3) and natural fires (PC4).

A cost analysis: processing maple syrup products

Treesearch

Neil K. Huyler; Lawrence D. Garrett

1979-01-01

A cost analysis of processing maple sap to syrup for three fuel types, oil-, wood-, and LP gas-fired evaporators, indicates that: (1) fuel, capital, and labor are the major cost components of processing sap to syrup; (2) wood-fired evaporators show a slight cost advantage over oil- and LP gas-fired evaporators; however, as the cost of wood approaches $50 per cord, wood...

Risk Based Reliability Centered Maintenance of DOD Fire Protection Systems

DTIC Science & Technology

1999-01-01

2.2.3 Failure Mode and Effect Analysis ( FMEA )............................ 2.2.4 Failure Mode Risk Characterization...Step 2 - System functions and functional failures definition Step 3 - Failure mode and effect analysis ( FMEA ) Step 4 - Failure mode risk...system). The Interface Location column identifies the location where the FMEA of the fire protection system began or stopped. For example, for the fire

Falsely elevated sodium levels during thiopental treatment in the ICU: technical interference on a laboratory device with important clinical relevance.

PubMed

Feyen, Bart F E; Coenen, Dries; Jorens, Philippe G; Wouters, Kristien; Maas, Andrew I R; Van Hoof, Viviane; Verbrugghe, Walter

2013-02-01

Thiopental is a cornerstone in the treatment of refractory status epilepticus and intractable intracranial hypertension. In our center we observed that thiopental might cause falsely elevated serum sodium levels. Triggered by a recent case experience of extremely elevated serum sodium levels during thiopental treatment, we retrospectively identified 53 patients treated with thiopental in our intensive care unit between 2007 and 2011 and evaluated electrolyte changes. We differentiated the analysis before and after introduction of a new device for sodium assays (Dimension Vista, Siemens) in the central laboratory in April 2010. Standardized in vitro laboratory tests were performed to study the effect of thiopental on sodium analysis. Before April 2010, serum sodium levels determined in the central laboratory showed a good agreement with the bedside point-of-care (POC) device during thiopental therapy with [sodium](laboratory) - [sodium](POC) of only 1.08 mmol/L (P = .0517). After April 2010, a strong discrepancy between laboratory values and POC values was observed with [sodium](laboratory) - [sodium](POC) = 11.57 mmol/L (P < .0001). Standardized in vitro testing confirmed that thiopental induced a dose-dependent false hypernatremia (P = .002). Thiopental treatment can result in falsely elevated serum sodium. This is a critical finding since high sodium levels preclude administrating mannitol or hypertonic saline for the treatment of elevated intracranial pressure. Moreover, a false high sodium level might lead to the inappropriate administration of hypotonic fluids potentially resulting in increased brain edema and even higher intracranial pressure. To our knowledge, this is the first paper describing this clinically relevant phenomenon.

Management of Sodium-reduced Meals at Worksite Cafeterias: Perceptions, Practices, Barriers, and Needs among Food Service Personnel

PubMed Central

Lee, Jounghee; Park, Sohyun

2015-01-01

Objectives The sodium content of meals provided at worksite cafeterias is greater than the sodium content of restaurant meals and home meals. The objective of this study was to assess the relationships between sodium-reduction practices, barriers, and perceptions among food service personnel. Methods We implemented a cross-sectional study by collecting data on perceptions, practices, barriers, and needs regarding sodium-reduced meals at 17 worksite cafeterias in South Korea. We implemented Chi-square tests and analysis of variance for statistical analysis. For post hoc testing, we used Bonferroni tests; when variances were unequal, we used Dunnett T3 tests. Results This study involved 104 individuals employed at the worksite cafeterias, comprised of 35 men and 69 women. Most of the participants had relatively high levels of perception regarding the importance of sodium reduction (very important, 51.0%; moderately important, 27.9%). Sodium reduction practices were higher, but perceived barriers appeared to be lower in participants with high-level perception of sodium-reduced meal provision. The results of the needs assessment revealed that the participants wanted to have more active education programs targeting the general population. The biggest barriers to providing sodium-reduced meals were use of processed foods and limited methods of sodium-reduced cooking in worksite cafeterias. Conclusion To make the provision of sodium-reduced meals at worksite cafeterias more successful and sustainable, we suggest implementing more active education programs targeting the general population, developing sodium-reduced cooking methods, and developing sodium-reduced processed foods. PMID:27169011

An approach to the real time risk evaluation system of boreal forest fire

NASA Astrophysics Data System (ADS)

Nakau, K.; Fukuda, M.; Kimura, K.; Hayasaka, H.; Tani, H.; Kushida, K.

2005-12-01

Huge boreal forest fire may cause massive impacts not only on global warming gas emission but also local communities. Thus, it is important to control forest fire. We collected data about boreal forest fire as satellite imagery and fire observation simultaneously in Alaska and east Siberia in summer fire seasons for these three years. Fire observation data was collected from aircraft flying between Japan and Europe. Fire detection results were compared with observed data to evaluate the accuracy and earliness of automatic detection. NOAA and MODIS satellite images covering Alaska and East Siberia are collected. We are also developing fire expansion simulation model to forecast the possible fire expansion area. On the basis of fire expansion forecast, risk analysis of possible fire expansion for decision aid of fire-fighting activities will be analyzed. To identify the risk of boreal forest fire and public concern about forest fire, we collected local news paper in Fairbanks, AK and discuss the statistics of articles related to forest fire on the newspaper.

Spatial mapping and analysis of aerosols during a forest fire using computational mobile microscopy

NASA Astrophysics Data System (ADS)

Wu, Yichen; Shiledar, Ashutosh; Luo, Yi; Wong, Jeffrey; Chen, Cheng; Bai, Bijie; Zhang, Yibo; Tamamitsu, Miu; Ozcan, Aydogan

2018-02-01

Forest fires are a major source of particulate matter (PM) air pollution on a global scale. The composition and impact of PM are typically studied using only laboratory instruments and extrapolated to real fire events owing to a lack of analytical techniques suitable for field-settings. To address this and similar field test challenges, we developed a mobilemicroscopy- and machine-learning-based air quality monitoring platform called c-Air, which can perform air sampling and microscopic analysis of aerosols in an integrated portable device. We tested its performance for PM sizing and morphological analysis during a recent forest fire event in La Tuna Canyon Park by spatially mapping the PM. The result shows that with decreasing distance to the fire site, the PM concentration increases dramatically, especially for particles smaller than 2 µm. Image analysis from the c-Air portable device also shows that the increased PM is comparatively strongly absorbing and asymmetric, with an aspect ratio of 0.5-0.7. These PM features indicate that a major portion of the PM may be open-flame-combustion-generated element carbon soot-type particles. This initial small-scale experiment shows that c-Air has some potential for forest fire monitoring.

Numerical study of fire whirlwind taking into account radiative heat transfer

NASA Astrophysics Data System (ADS)

Sakai, S.; Miyagi, N.

2010-06-01

The fire whirlwind is a strong swirling flow with flame and spark, which may occur in the case of, widespread fire in the urban region by an earthquake disaster or an air raid, and a large-scale fire such as a forest fire. Fire whirlwind moves and promotes spread of fire and may extend serious damage rapidly. In this study, performing the numerical analysis of fire whirlwind with respect to scale effect, it is examined whether a relationship exists between a real phenomenon and the phenomenon in the reduction model with taking into account radiative heat transfer. Three dimensional analyses are performed to investigate the thermal and flow fields by using the analytical software FLUENT6.3. It is analyzed that those swirling flow in original scale, 1/10 scale, 1/50 scale, 1/100 scale from the original brake out to vanish. As an analytical condition, parameter calculation is repeated to get the velocity of a parallel flow which is the easiest to occur the swirling flow for each reduction model, and then scale effect is discussed by comparing the velocity of the natural convection, the velocity of the parallel flow, the center pressure of the whirlwind and the continuance time of the swirling flow. The analysis model of C-character heat source model is performed as well as the analysis in L-character model, which is one of the representative example of the fire whirlwind occurred at Tokyo in the Great Kanto Earthquake (1923). The result of the numerical analysis shows that there is a scale effect to the speed of the parallel flow to generate the swirling flow.

Comparative Analysis of the Reliability of Steel Structure with Pinned and Rigid Nodes Subjected to Fire

NASA Astrophysics Data System (ADS)

Kubicka, Katarzyna; Radoń, Urszula; Szaniec, Waldemar; Pawlak, Urszula

2017-10-01

The paper concerns the reliability analysis of steel structures subjected to high temperatures of fire gases. Two types of spatial structures were analysed, namely with pinned and rigid nodes. The fire analysis was carried out according to prescriptions of Eurocode. The static-strength analysis was conducted using the finite element method (FEM). The MES3D program, developed by Szaniec (Kielce University of Technology, Poland), was used for this purpose. The results received from MES3D made it possible to carry out the reliability analysis using the Numpress Explore program that was developed at the Institute of Fundamental Technological Research of the Polish Academy of Sciences [9]. The measurement of reliability of structures is the Hasofer-Lind reliability index (β). The reliability analysis was carried out according to approximation (FORM, SORM) and simulation (Importance Sampling, Monte Carlo) methods. As the fire progresses, the value of reliability index decreases. The analysis conducted for the study made it possible to evaluate the impact of node types on those changes. In real structures, it is often difficult to define correctly types of nodes, so some simplifications are made. The presented analysis contributes to the recognition of consequences of such assumptions for the safety of structures, subjected to fire.

Broadleaf deciduous forest counterbalanced the direct effect of climate on Holocene fire regime in hemiboreal/boreal region (NE Europe)

NASA Astrophysics Data System (ADS)

Feurdean, Angelica; Veski, Siim; Florescu, Gabriela; Vannière, Boris; Pfeiffer, Mirjam; O'Hara, Robert B.; Stivrins, Normunds; Amon, Leeli; Heinsalu, Atko; Vassiljev, Jüri; Hickler, Thomas

2017-08-01

Disturbances by fire are essential for the functioning of boreal/hemiboreal forests, but knowledge of long-term fire regime dynamics is limited. We analysed macrocharcoal morphologies and pollen of a sediment record from Lake Lielais Svētiņu (eastern Latvia), and in conjunction with fire traits analysis present the first record of Holocene variability in fire regime, fuel sources and fire types in boreal forests of the Baltic region. We found a phase of moderate to high fire activity during the cool and moist early (mean fire return interval; mFRI of ∼280 years; 11,700-7500 cal yr BP) and the late (mFRI of ∼190 years; 4500-0 cal yr BP) Holocene and low fire activity (mFRI of ∼630 years) during the Holocene Thermal Optimum (7500-4500 cal yr BP). Charcoal morphotypes and the pollen record show the predominance of frequent surface fires, occasionally transitioning to the crown during Pinus sylvestris-Betula boreal forests and less frequent surface fires during the dominance of temperate deciduous forests. In contrast to the prevailing opinion that fires in boreal forests are mostly low to moderate severity surface fires, we found evidence for common occurrence of stand-replacing crown fires in Picea abies canopy. Our results highlight that charcoal morphotypes analysis allows for distinguishing the fuel types and surface from crown fires, therefore significantly advancing our interpretation of fire regime. Future warmer temperatures and increase in the frequency of dry spells and abundant biomass accumulation can enhance the fire risk on the one hand, but will probably promote the expansion of broadleaf deciduous forests to higher latitudes, on the other hand. By highlighting the capability of broadleaf deciduous forests to act as fire-suppressing landscape elements, our results suggest that fire activity may not increase in the Baltic area under future climate change.

A comprehensive analysis of sodium levels in the Canadian packaged food supply

PubMed Central

Arcand, JoAnne; Au, Jennifer T.C.; Schermel, Alyssa; L’Abbe, Mary R.

2016-01-01

Background Population-wide sodium reduction strategies aim to reduce the cardiovascular burden of excess dietary sodium. Lowering sodium in packaged foods, which contribute the most sodium to the diet, is an important intervention to lower population intakes. Purpose To determine sodium levels in Canadian packaged foods and evaluate the proportion of foods meeting sodium benchmark targets set by Health Canada. Methods A cross-sectional analysis of 7234 packaged foods available in Canada in 2010–11. Sodium values were obtained from the Nutrition Facts table. Results Overall, 51.4% of foods met one of the sodium benchmark levels: 11.5% met Phase 1, 11.1% met Phase 2, and 28.7% met 2016 goal (Phase 3) benchmarks. Food groups with the greatest proportion meeting goal benchmarks were dairy (52.0%) and breakfast cereals (42.2%). Overall 48.6% of foods did not meet any benchmark level and 25% of all products exceeded maximum levels. Meats (61.2%) and canned vegetables/legumes and legumes (29.6%) had the most products exceeding maximum levels. There was large variability in the range of sodium within and between food categories. Food categories highest in sodium (mg/serving) were dry, condensed and ready-to-serve soups (834 ± 256, 754 ± 163, and 636 ± 173, respectively), oriental noodles (783 ± 433), broth (642 ± 239), and frozen appetizers/sides (642 ± 292). Conclusion These data provide a critical baseline assessment for monitoring sodium levels in Canadian foods. While some segments of the market are making progress towards sodium reduction, all sectors need encouragement to continue to reduce the amount of sodium added during food processing. PMID:24842740

Dietary Sodium Consumption Predicts Future Blood Pressure and Incident Hypertension in the Japanese Normotensive General Population.

PubMed

Takase, Hiroyuki; Sugiura, Tomonori; Kimura, Genjiro; Ohte, Nobuyuki; Dohi, Yasuaki

2015-07-29

Although there is a close relationship between dietary sodium and hypertension, the concept that persons with relatively high dietary sodium are at increased risk of developing hypertension compared with those with relatively low dietary sodium has not been studied intensively in a cohort. We conducted an observational study to investigate whether dietary sodium intake predicts future blood pressure and the onset of hypertension in the general population. Individual sodium intake was estimated by calculating 24-hour urinary sodium excretion from spot urine in 4523 normotensive participants who visited our hospital for a health checkup. After a baseline examination, they were followed for a median of 1143 days, with the end point being development of hypertension. During the follow-up period, hypertension developed in 1027 participants (22.7%). The risk of developing hypertension was higher in those with higher rather than lower sodium intake (hazard ratio 1.25, 95% CI 1.04 to 1.50). In multivariate Cox proportional hazards regression analysis, baseline sodium intake and the yearly change in sodium intake during the follow-up period (as continuous variables) correlated with the incidence of hypertension. Furthermore, both the yearly increase in sodium intake and baseline sodium intake showed significant correlations with the yearly increase in systolic blood pressure in multivariate regression analysis after adjustment for possible risk factors. Both relatively high levels of dietary sodium intake and gradual increases in dietary sodium are associated with future increases in blood pressure and the incidence of hypertension in the Japanese general population. © 2015 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

Aviation Engine Test Facilities (AETF) fire protection study

NASA Astrophysics Data System (ADS)

Beller, R. C.; Burns, R. E.; Leonard, J. T.

1989-07-01

An analysis is presented to the effectiveness of various types of fire fighting agents in extinguishing the kinds of fires anticipated in Aviation Engine Test Facilities (AETF), otherwise known as Hush Houses. The agents considered include Aqueous Film-Forming Foam, Halon 1301, Halon 1211 and water. Previous test work has shown the rapidity with which aircraft, especially high performance aircraft, can be damaged by fire. Based on this, tentative criteria for this evaluation included a maximum time of 20 s from fire detection to extinguishment and a period of 30 min in which the agent would prevent reignition. Other issues examined included: toxicity, corrosivity, ease of personnel egress, system reliability, and cost effectiveness. The agents were evaluated for their performance in several fire scenarios, including: under frame fire, major engine fire, engine disintegration fire, high-volume pool fire with simultaneous spill fire, internal electrical fire, and runaway engine fire.

Assessing the influence of small fires on trends in fire regime features at mainland Spain

NASA Astrophysics Data System (ADS)

Jiménez-Ruano, Adrián; Rodrigues Mimbrero, Marcos; de la Riva Fernández, Juan

2017-04-01

Small fires, i.e. fires smaller than 1 Ha, represent a huge proportion of total wildfire occurrence in the Mediterranean region. In the case of Spain, around 53% of fires in the period 1988-2013 fall into this category according to the Spanish EGIF statistics. However, the proportion of small fires is not stationary over time. Small fires are usually excluded from most analysis, given the chance of introducing or falling into temporal bias, being almost mandatory in those assessments using data before the 90s. Inconsistences and inhomogeneity problems related to the diversity of criteria and/or registration procedures among Autonomous Regions are found before that date, although it is widely agreed that small fires are consistently registered starting from 1988. Nevertheless, in terms of fire regimen characterization it is important to know to what extent small fires contribute to the overall fire behaviour. The aim of this study is to analyse spatial-temporal trends of several fire features such as total number of fires and burned area, number and burned area of natural and human fires, and the proportion of natural/human cause in the period 1988-2013 at province level (NUTS3). The analysis is conducted at the mainland Spain at annual and seasonal time scales. We are mainly interested in exploring differences in spatial-temporal trends including or excluding small fires and dealing with them separately as well. This allows determining the extent to which small fires may affect fire regime characterization. We employed a Mann-Kendall test for trend detection and Sen's slope to evaluate the magnitude of the change. Both tests were applied for each fire feature aggregated at NUTS3 level for both autumn-winter and spring-summer seasons. Our results show significant changes in the evolution of annual wildfire frequency; especially strong when small fires are accounted for. A similar outcome was observed in natural and human number fires during the spring-summer season. The increase in number of fires seems to be reversed during autumn-winter. At seasonal scale, the inclusion of small fires allows to detect significant trends in all of fire frequency features, except natural fires. In turn, neither burned area features do not significantly affect the trends through incorporating small fires. Therefore, the inclusion/exclusion of small fires do influence observed trends mostly in terms of fire frequency.

Meta-analysis of avian and small-mammal response to fire severity and fire surrogate treatments in U.S. fire-prone forests.

PubMed

Fontaine, Joseph B; Kennedy, Patricia L

2012-07-01

Management in fire-prone ecosystems relies widely upon application of prescribed fire and/or fire surrogate (e.g., forest thinning) treatments to maintain biodiversity and ecosystem function. Recently, published literature examining wildlife response to fire and fire management has increased rapidly. However, none of this literature has been synthesized quantitatively, precluding assessment of consistent patterns of wildlife response among treatment types. Using meta-analysis, we examined the scientific literature on vertebrate demographic responses to burn severity (low/moderate, high), fire surrogates (forest thinning), and fire and fire surrogate combined treatments in the most extensively studied fire-prone, forested biome (forests of the United States). Effect sizes (magnitude of response) and their 95% confidence limits (response consistency) were estimated for each species-by-treatment combination with two or more observations. We found 41 studies of 119 bird and 17 small-mammal species that examined short-term responses (< or =4 years) to thinning, low/moderate- and high-severity fire, and thinning plus prescribed fire; data on other taxa and at longer time scales were too sparse to permit quantitative assessment. At the stand scale (<50 ha), thinning and low/moderate-severity fire demonstrated similar response patterns in these forests. Combined thinning plus prescribed fire produced a higher percentage of positive responses. High-severity fire provoked stronger responses, with a majority of species possessing higher or lower effect sizes relative to fires of lower severity. In the short term and at fine spatial scales, fire surrogate forest-thinning treatments appear to effectively mimic low/moderate-severity fire, whereas low/moderate-severity fire is not a substitute for high-severity fire. The varied response of taxa to each of the four conditions considered makes it clear that the full range of fire-based disturbances (or their surrogates) is necessary to maintain a full complement of vertebrate species, including fire-sensitive taxa. This is especially true for high-severity fire, where positive responses from many avian taxa suggest that this disturbance (either as wildfire or prescribed fire) should be included in management plans where it is consistent with historic fire regimes and where maintenance of regional vertebrate biodiversity is a goal.

Modeling of Electrical Cable Failure in a Dynamic Assessment of Fire Risk

NASA Astrophysics Data System (ADS)

Bucknor, Matthew D.

Fires at a nuclear power plant are a safety concern because of their potential to defeat the redundant safety features that provide a high level of assurance of the ability to safely shutdown the plant. One of the added complexities of providing protection against fires is the need to determine the likelihood of electrical cable failure which can lead to the loss of the ability to control or spurious actuation of equipment that is required for safe shutdown. A number of plants are now transitioning from their deterministic fire protection programs to a risk-informed, performance based fire protection program according to the requirements of National Fire Protection Association (NFPA) 805. Within a risk-informed framework, credit can be taken for the analysis of fire progression within a fire zone that was not permissible within the deterministic framework of a 10 CFR 50.48 Appendix R safe shutdown analysis. To perform the analyses required for the transition, plants need to be able to demonstrate with some level of assurance that cables related to safe shutdown equipment will not be compromised during postulated fire scenarios. This research contains the development of new cable failure models that have the potential to more accurately predict electrical cable failure in common cable bundle configurations. Methods to determine the thermal properties of the new models from empirical data are presented along with comparisons between the new models and existing techniques used in the nuclear industry today. A Dynamic Event Tree (DET) methodology is also presented which allows for the proper treatment of uncertainties associated with fire brigade intervention and its effects on cable failure analysis. Finally a shielding analysis is performed to determine the effects on the temperature response of a cable bundle that is shielded from a fire source by an intervening object such as another cable tray. The results from the analyses demonstrate that models of similar complexity to existing cable failure techniques and tuned to empirical data can better approximate the temperature response of a cables located in tightly packed cable bundles. The new models also provide a way to determine the conditions insides a cable bundle which allows for separate treatment of cables on the interior of the bundle from cables on the exterior of the bundle. The results from the DET analysis show that the overall assessed probability of cable failure can be significantly reduced by more realistically accounting for the influence that the fire brigade has on a fire progression scenario. The shielding analysis results demonstrate a significant reduction in the temperature response of a shielded versus a non-shielded cable bundle; however the computational cost of using a fire progression model that can capture these effects may be prohibitive for performing DET analyses with currently available computational fluid dynamics models and computational resources.

Alternative fuels in fire debris analysis: biodiesel basics.

PubMed

Stauffer, Eric; Byron, Doug

2007-03-01

Alternative fuels are becoming more prominent on the market today and, soon, fire debris analysts will start seeing them in liquid samples or in fire debris samples. Biodiesel fuel is one of the most common alternative fuels and is now readily available in many parts of the United States and around the world. This article introduces biodiesel to fire debris analysts. Biodiesel fuel is manufactured from vegetable oils and/or animal oils/fats. It is composed of fatty acid methyl esters (FAMEs) and is sold pure or as a blend with diesel fuel. When present in fire debris samples, it is recommended to extract the debris using passive headspace concentration on activated charcoal, possibly followed by a solvent extraction. The gas chromatographic analysis of the extract is first carried out with the same program as for regular ignitable liquid residues, and second with a program adapted to the analysis of FAMEs.

Enhanced ionic conductivity in planar sodium-β"-alumina electrolyte for electrochemical energy storage applications.

PubMed

La Rosa, Daniela; Monforte, Giuseppe; D'Urso, Claudia; Baglio, Vincenzo; Antonucci, Vincenzo; Aricò, Antonino S

2010-12-17

Solid Na-β"-Al₂O₃ electrolyte is prepared by a simple chemical route involving a pseudo-boehmite precursor and thermal treatment. Boehmite powder is used for manufacturing the planar electrolyte with appropriate bulk density after firing at 1500 °C. The structure, morphology, and surface properties of precursor powders and sintered electrolytes are investigated by X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). As shown by XRD and TEM analyses, nanometer-sized particles are obtained for the boehmite precursor and a pure crystallographic phase is achieved for the sintered electrolyte. SEM analysis of the cross-section indicates good sintering characteristics. XPS shows a higher Na/Al atomic ratio on the surface for the planar electrolyte compared to a commercial tubular electrolyte (0.57 vs. 0.46). Energy-dispersive X-ray microanalysis (EDX) shows an Na/Al ratio in the bulk of 0.16, similar in the two samples. The ionic conductivity of the planar electrolyte is larger than that measured on a commercial tube of sodium-β"-alumina in a wide temperature range. At 350 °C, conductivity values of 0.5 S cm⁻¹ and 0.26 S cm⁻¹ are obtained for the planar electrolyte and the commercial tube, respectively. AC-impedance spectra show smaller grain boundary effects in the planar electrolyte than in the tubular electrolyte. These favorable properties may increase the perspectives for applying planar Na-β"-Al₂O₃ electrolytes in high-temperature batteries.

Impact of an intense rainfall event on soil properties following a wildfire in a Mediterranean environment (North-East Spain).

PubMed

Francos, Marcos; Pereira, Paulo; Alcañiz, Meritxell; Mataix-Solera, Jorge; Úbeda, Xavier

2016-12-01

Intense rainfall events after severe wildfires can have an impact on soil properties, above all in the Mediterranean environment. This study seeks to examine the immediate impact and the effect after a year of an intense rainfall event on a Mediterranean forest affected by a high severity wildfire. The work analyses the following soil properties: soil aggregate stability, total nitrogen, total carbon, organic and inorganic carbon, the C/N ratio, carbonates, pH, electrical conductivity, extractable calcium, magnesium, sodium, potassium, available phosphorous and the sodium and potassium adsorption ratio (SPAR). We sampled soils in the burned area before, immediately after and one year after the rainfall event. The results showed that the intense rainfall event did not have an immediate impact on soil aggregate stability, but a significant difference was recorded one year after. The intense precipitation did not result in any significant changes in soil total nitrogen, total carbon, inorganic carbon, the C/N ratio and carbonates during the study period. Differences were only registered in soil organic carbon. The soil organic carbon content was significantly higher after the rainfall than in the other sampling dates. The rainfall event did increase soil pH, electrical conductivity, major cations, available phosphorous and the SPAR. One year after the fire, a significant decrease in soil aggregate stability was observed that can be attributed to high SPAR levels and human intervention, while the reduction in extractable elements can be attributed to soil leaching and vegetation consumption. Overall, the intense rainfall event, other post-fire rainfall events and human intervention did not have a detrimental impact on soil properties in all probability owing to the flat plot topography. Copyright © 2016 Elsevier B.V. All rights reserved.

Analysis of fire deaths in Poland and influence of smoke toxicity.

PubMed

Giebułtowicz, Joanna; Rużycka, Monika; Wroczyński, Piotr; Purser, David A; Stec, Anna A

2017-08-01

Dwelling fires have changed over the years because building contents and the materials used in then have changed. They all contribute to an ever-growing diversity of chemical species found in fires, many of them highly toxic. These arise largely from the changing nature of materials in interior finishes and furniture, with an increasing content of synthetic materials containing higher levels of nitrogen, halogen and phosphorus additives. While there is still a belief that carbon monoxide is the major lethal toxic agent in fires, the hydrogen cyanide and acid gases released from these additives are now well-recognised as major contributory causes of incapacitation, morbidity and mortality in domestic fires. Data for the total number of 263 fire death cases in the Mazowieckie region (mainly Warsaw area) of Poland between 2003-2011 for dwellings fires were obtained from pathologists, forensic toxicologists, fire fighters and analysed. Factors contributing to the death such as the findings of the full post mortem examination (age, sex, health status, burns), the toxicological analysis (carbon monoxide, alcohol etc.), and a thorough investigation of the scene (fire conditions, fuel, etc.) were taken into account and are summarised. Copyright © 2017 Elsevier B.V. All rights reserved.

Development and analysis of a 12-year daily 1-km forest fire dataset across North America from NOAA/AVHRR

Treesearch

Ruiliang Pu; Zhanqing Li; Peng Gong; Ivan Csiszar; Robert Fraser; Wei-Min Hao; Shobha Kondragunta; Fuzhong Weng

2007-01-01

Fires in boreal and temperate forests play a significant role in the global carbon cycle. While forest fires in North America (NA) have been surveyed extensively by U.S. and Canadian forest services, most fire records are limited to seasonal statistics without information on temporal evolution and spatial expansion. Such dynamic information is crucial for modeling fire...

Analysis of the Large Urban Fire Environment. Part 1. Theory

DTIC Science & Technology

1982-07-01

the fire. It is the buoyancy-generated pressure forces, and not diffusive entrainment, that control the low-level induction of ambient air into the...18-- IV. RESULTS FLAMBEAU FIRES The multiple-fuel-bed Flambeau fires (Countryman, 1969; Palmer, 1981] were large, controlled burns conducted to...Station Northern Forest Fire Laboratory Alexandria, VA 22314 (12) Missoula, MT 59801 (1) Department of Defense 2. Mr. Clay F. Butler Command and Control

49 CFR 238.103 - Fire safety.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Fire safety. 238.103 Section 238.103... § 238.103 Fire safety. (a) Materials. (1) Materials used in constructing a passenger car or a cab of a... section at the time it was tested. (c) Fire safety analysis for procuring new passenger cars and...

49 CFR 238.103 - Fire safety.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Fire safety. 238.103 Section 238.103... § 238.103 Fire safety. (a) Materials. (1) Materials used in constructing a passenger car or a cab of a... section at the time it was tested. (c) Fire safety analysis for procuring new passenger cars and...

49 CFR 238.103 - Fire safety.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Fire safety. 238.103 Section 238.103... § 238.103 Fire safety. (a) Materials. (1) Materials used in constructing a passenger car or a cab of a... section at the time it was tested. (c) Fire safety analysis for procuring new passenger cars and...

Terminology and biology of fire scars in selected central hardwoods

Treesearch

Kevin T. Smith; Elaine Kennedy Sutherland

2001-01-01

Dendrochronological analysis of fire scars requires tree survival of fire exposure. Trees survive fire exposure by: (1) avoidance of injury through constitutive protection and (2) induced defense. Induced defenses include (a) compartmentalization processes that resist the spread of injury and infection and (b) closure processes that restore the continuity of the...

An Evaluation of Historical Fire Occurrence, Drought and the El Niño Southern Oscillation in the Southcentral United States

NASA Astrophysics Data System (ADS)

Rooney, M.; Stambaugh, M. C.

2016-12-01

Wildfire occurrence in the forested ecosystems of the southcentral United States is driven by conditions of drought. Historically, fire intervals varied temporally and spatially - forced by climate, humans, and environmental conditions. Thus, proxy records are required to assess the relationships between fire occurrence, drought, and the El Niño Southern Oscillation (ENSO). Fire scar data from tree-rings are well-suited to assess historical fire regimes in this region, paired with reconstructions of drought and ENSO that have been developed from networks of ring-width chronologies across the United States. This study combines fire-scar data from twelve different sites in the southcentral United States, including two new fire-history reconstructions. Fire data incorporates 665 fires across Eastern Oklahoma and Northern Texas from 1637-2014. These robust reconstructions of post oak (Quercus stellata) evaluate the variability in fire activity and its association to drought and ENSO. Climate-explained growth variance in post-oak chronologies is strong in this region, providing powerful proxy information in the derived chronologies. In general, most fires occur during the La Niña portion of the ENSO cycle. Many severe fires correspond with drought, and results from super-posed epoch analysis suggest a significant relationship between fire event years and drought conditions in the full period of record. Analysis reveals differences in the relationships of fire, drought and ENSO through time, corresponding to changes in human settlement in the region. Understanding the spatial and temporal relationships that exist between fire occurrence, drought, and ENSO aid in quantifying disturbance characteristics and their associations to climate in the forested ecosystems of the southcentral United States.

Modeling anthropogenic and natural fire ignitions in an inner-alpine valley

NASA Astrophysics Data System (ADS)

Vacchiano, Giorgio; Foderi, Cristiano; Berretti, Roberta; Marchi, Enrico; Motta, Renzo

2018-03-01

Modeling and assessing the factors that drive forest fire ignitions is critical for fire prevention and sustainable ecosystem management. In southern Europe, the anthropogenic component of wildland fire ignitions is especially relevant. In the Alps, however, the role of fire as a component of disturbance regimes in forest and grassland ecosystems is poorly known. The aim of this work is to model the probability of fire ignition for an Alpine region in Italy using a regional wildfire archive (1995-2009) and MaxEnt modeling. We analyzed separately (i) winter forest fires, (ii) winter fires on grasslands and fallow land, and (iii) summer fires. Predictors were related to morphology, climate, and land use; distance from infrastructures, number of farms, and number of grazing animals were used as proxies for the anthropogenic component. Collinearity among predictors was reduced by a principal component analysis. Regarding ignitions, 30 % occurred in agricultural areas and 24 % in forests. Ignitions peaked in the late winter-early spring. Negligence from agrosilvicultural activities was the main cause of ignition (64 %); lightning accounted for 9 % of causes across the study time frame, but increased from 6 to 10 % between the first and second period of analysis. Models for all groups of fire had a high goodness of fit (AUC 0.90-0.95). Temperature was proportional to the probability of ignition, and precipitation was inversely proportional. Proximity from infrastructures had an effect only on winter fires, while the density of grazing animals had a remarkably different effect on summer (positive correlation) and winter (negative) fires. Implications are discussed regarding climate change, fire regime changes, and silvicultural prevention. Such a spatially explicit approach allows us to carry out spatially targeted fire management strategies and may assist in developing better fire management plans.

Strategy for increasing the participation of masyarakat peduli api in forest fire control

NASA Astrophysics Data System (ADS)

Ni’mah, N. L. K.; Herdiansyah, H.; Soesilo, T. E. B.; Mutia, E. F.

2018-03-01

Forest fires have negative impact on ecology, health, and damage economic activities. One of conservation areas facing the threat of forest fire is Gunung Ciremai National Park. This research aims to formulate a strategy to increase the participation of Masyarakat Peduli Api in the effort of forest fire control. This research use quantitative method with SWOT analysis. Expert consisting of representatives from the national park, Ministry of Environment and Forestry, and BPBD Kuningan Regency. An alternative strategy based on SWOT analysis is in quadrant 1 with coordinate point (0,39; 1,23). The position shows that sustainability of national park management through forest fire control can be done with an aggressive strategy. That is maximizing the strength that is owned with its potential as an ecotourism area to increase community motivation to engage in forest fire control activities. Provision of tourism management licenses will create employment opportunities and increase income for the community so it is expected to increase community participation to prevent the occurrence of forest fires rather than forest fire prevention.

Enclosure fire hazard analysis using relative energy release criteria. [burning rate and combustion control

NASA Technical Reports Server (NTRS)

Coulbert, C. D.

1978-01-01

A method for predicting the probable course of fire development in an enclosure is presented. This fire modeling approach uses a graphic plot of five fire development constraints, the relative energy release criteria (RERC), to bound the heat release rates in an enclosure as a function of time. The five RERC are flame spread rate, fuel surface area, ventilation, enclosure volume, and total fuel load. They may be calculated versus time based on the specified or empirical conditions describing the specific enclosure, the fuel type and load, and the ventilation. The calculation of these five criteria, using the common basis of energy release rates versus time, provides a unifying framework for the utilization of available experimental data from all phases of fire development. The plot of these criteria reveals the probable fire development envelope and indicates which fire constraint will be controlling during a criteria time period. Examples of RERC application to fire characterization and control and to hazard analysis are presented along with recommendations for the further development of the concept.

Trends in Dietary Sodium from Food Sources in Australian Children and Adolescents from 2007 to 2011/12.

PubMed

Grimes, Carley A; Szymlek-Gay, Ewa A; Nowson, Caryl A

2018-05-01

In western countries, most children eat more sodium than is recommended. In Australia in 2009, voluntary sodium reformulation targets were adopted for nine categories of processed foods, but the impact of this initiative on children's sodium intake has not been assessed. To compare sodium consumption of Australian children aged 2 to 16 years from 2007 to 2011/12. Cross-sectional analysis of data from the 2007 Children's Nutrition and Physical Activity Survey (n=4,487) and the 2011/12 National Nutrition and Physical Activity Survey (n=2,548). A nationally representative sample of 6,705 Australian children aged 2 to 16 years who provided plausible 24-hour dietary recall data according to Goldberg cutoffs for misreporting of energy intake. Mean intakes of energy, sodium, and sodium density (mg/1,000 kcal) were assessed via one 24-hour dietary recall; measurement error models with up to two 24-hour dietary recalls were used to estimate usual sodium intake and the proportion of children exceeding the age-specific upper level for sodium. Statistical analysis incorporated survey weights and accounted for the complex survey design. Two-sample t-tests and two-sample test of proportions were used to assess differences in continuous and categorical variables between survey years. Dietary sodium declined by 8% between 2007 and 2011/12 (-188±SE 31 mg/day; P<0.001), and this was in conjunction with a 5% reduction in energy intake (98±19 kcal/day; P<0.001). When stratified by age group, significant reductions in sodium intake remained across all four age groups (ie, 2-3 years, 4-8 years, 9-13 years, and 14-16 years); similarly, with the exception of 2- to 3-year-old children, reductions in energy intake were observed across all other age groups. Overall sodium density declined by 2% (-29 mg/1,000 kcal/day; P=0.01); however, in age subgroup analysis the decline in sodium density only remained among children aged 2 to 3 years. The upper level for sodium was exceeded by 94% or more children in 2007 and 78% or more in 2011/2012. Although results suggest a small reduction in reported sodium intake over 5 years, most children in 2011/12 had a sodium intake that exceeded the recommended upper level. Ongoing efforts to reduce sodium in the diets of Australian children are required. Copyright © 2018 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

Using risk analysis to reveal opportunities for the management of unplanned ignitions in wilderness

Treesearch

Kevin Barnett; Carol Miller; Tyron J. Venn

2016-01-01

A goal of fire management in wilderness is to allow fire to play its natural ecological role without intervention. Unfortunately, most unplanned ignitions in wilderness are suppressed, in part because of the risk they might pose to values outside of the wilderness. We capitalize on recent advances in fire risk analysis to demonstrate a risk-based approach for revealing...

Fire Disasters in the Twentieth Century

PubMed Central

Cavallini, M.; Papagni, M.F.; Baruffaldi Preis, F.W.

2007-01-01

Summary In the field of natural and man-made disasters, fire has played a predominant role. A report is presented of fire disasters in the twentieth century, with a chronological analysis of different worldwide typologies. PMID:21991077

Loss of Sodium-Activated Potassium Channel Slack and FMRP Differentially Affect Social Behavior in Mice.

PubMed

Bausch, Anne E; Ehinger, Rebekka; Straubinger, Julia; Zerfass, Patrick; Nann, Yvette; Lukowski, Robert

2018-05-31

The sodium-activated potassium channel Slack (Slo2.2) is widely expressed in central and peripheral neurons where it is supposed to shape firing properties important for neuronal excitability. Slack activity is enhanced by interaction with the Fragile-X-Mental-Retardation-Protein (FMRP) and loss of FMRP leads to decreased sodium-activated potassium currents in medial nucleus of the trapezoid body neurons of the Fmr1-knockout (KO) mouse representing a mouse model of the human Fragile-X-Syndrome (FXS) and autism. Autism is a frequent comorbidity of FXS, but it is unclear whether Slack is involved in autistic or related conditions of FXS in vivo. By applying a wide range of behavioral tests, we compared social and autism-related behaviors in Slack- and FMRP-deficient mice. In our hands, as expected, FMRP-deficiency causes autism-related behavioral changes in nesting and in a marble-burying test. In contrast, Slack-deficient males exhibited specific abnormalities in sociability in direct and indirect social interaction tests. Hence, we show for the first time that a proper Slack channel function is mandatory for normal social behavior in mice. Nevertheless, as deficits in social behaviors seem to occur independently from each other in FMRP and Slack null mutants, we conclude that Slack is not involved in the autistic phenotype of FMRP KO mice. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.

Income, housing, and fire injuries: a census tract analysis.

PubMed

Shai, Donna

2006-01-01

This study investigates the social and demographic correlates of nonfatal structural fire injury rates for the civilian population for Philadelphia census tracts during 1993-2001. The author analyzed 1,563 fire injuries by census tract using the 1990 census (STF 3) and unpublished data from the Office of the Fire Marshal of the Philadelphia Fire Department. Injury rates were calculated per 1,000 residents of a given census tract. Multiple regression was used to determine significant variables in predicting fire injuries in a given census tract over a nine-year period and interaction effects between two of these variables-age of housing and income. Multiple regression analysis indicates that older housing (prior to 1940), low income, the prevalence of vacant houses, and the ability to speak English have significant independent effects on fire injury rates in Philadelphia. In addition, the results show a significant interaction between older housing and low income. Given the finding of very high rates of fire injuries in census tracts that are both low income and have older housing, fire prevention units can take preventative measures. Fire protection devices, especially smoke alarms, should be distributed in the neighborhoods most at risk. Multiple occupancy dwellings should have sprinkler systems and fire extinguishers. Laws concerning the maintenance of older rental housing need to be strictly enforced. Vacant houses should be effectively boarded up or renovated for residential use. Fire prevention material should be distributed in a number of languages to meet local needs.

A GIS-based decision support system for determining the shortest and safest route to forest fires: a case study in Mediterranean Region of Turkey.

PubMed

Akay, Abdullah E; Wing, Michael G; Sivrikaya, Fatih; Sakar, Dursun

2012-03-01

The ability of firefighting vehicles and staff to reach a fire area as quickly as possible is critical in fighting against forest fires. In this study, a Geographical Information System-based decision support system was developed to assist fire managers in determining the fastest and the safest or more reliable access routes from firefighting headquarters to fire areas. The decision support system was tested in the Kahramanmaras Forestry Regional Directoratein the Mediterranean region of Turkey. The study area consisted of forested lands which had been classified according to fire sensitivity. The fire response routing simulations considered firefighting teams located in 20 firefighting headquarter locations. The road network, the locations of the firefighting headquarters, and possible fire locations were mapped for simulation analysis. In alternative application simulations, inaccessible roads which might be closed due to fire or other reasons were indicated in the network analysis so that the optimum route was not only the fastest but also the safest and most reliable path. The selection of which firefighting headquarters to use was evaluated by considering critical response time to potential fire areas based on fire sensitivity levels. Results indicated that new firefighting headquarters should be established in the region in order to provide sufficient firefighting response to all forested lands. In addition, building new fire access roads and increasing the design speed on current roads could also increase firefighting response capabilities within the study area.

Investigating Over Critical Thresholds of Forest Megafires Danger Conditions in Europe Utilising the ECMWF ERA-Interim Reanalysis

NASA Astrophysics Data System (ADS)

Petroliagkis, Thomas I.; Camia, Andrea; Liberta, Giorgio; Durrant, Tracy; Pappenberger, Florian; San-Miguel-Ayanz, Jesus

2014-05-01

The European Forest Fire Information System (EFFIS) has been established by the Joint Research Centre (JRC) and the Directorate General for Environment (DG ENV) of the European Commission (EC) to support the services in charge of the protection of forests against fires in the EU and neighbour countries, and also to provide the EC services and the European Parliament with information on forest fires in Europe. Within its applications, EFFIS provides current and forecast meteorological fire danger maps up to 6 days. Weather plays a key role in affecting wildfire occurrence and behaviour. Meteorological parameters can be used to derive meteorological fire weather indices that provide estimations of fire danger level at a given time over a specified area of interest. In this work, we investigate the suitability of critical thresholds of fire danger to provide an early warning for megafires (fires > 500 ha) over Europe. Past trends of fire danger are analysed computing daily fire danger from weather data taken from re-analysis fields for a period of 31 years (1980 to 2010). Re-analysis global data sets coming from the construction of high-quality climate records, which combine past observations collected from many different observing and measuring platforms, are capable of describing how Fire Danger Indices have evolved over time at a global scale. The latest and most updated ERA-Interim dataset of the European Centre for Medium-Range Weather Forecast (ECMWF) was used to extract meteorological variables needed to compute daily values of the Canadian Fire Weather Index (CFWI) over Europe, with a horizontal resolution of about 75x75 km. Daily time series of CFWI were constructed and analysed over a total of 1,071 European NUTS3 centroids, resulting in a set of percentiles and critical thresholds. Such percentiles could be used as thresholds to help fire services establish a measure of the significance of CFWI outputs as they relate to levels of fire potential, fuel conditions and fire danger. Median percentile values of fire days accumulated over the 31-year period were compared to median values of all days from that period. As expected, the CWFI time series exhibit different values on fire days than on all days. In addition, a percentile analysis was performed in order to determine the behaviour of index values corresponding to fire events falling into the megafire category. This analysis resulted in a set of critical thresholds based on percentiles. By utilising such thresholds, an initial framework of an early warning system has being established. By lowering the value of any of these thresholds, the number of hits could be increased until all extremes were captured (resulting in zero misses). However, in doing so, the number of false alarms tends to increase significantly. Consequently, an optimal trade-off between hits and false alarms has to be established when setting different (critical) CFWI thresholds.

Process for converting sodium nitrate-containing, caustic liquid radioactive wastes to solid insoluble products

DOEpatents

Barney, Gary S.; Brownell, Lloyd E.

1977-01-01

A method for converting sodium nitrate-containing, caustic, radioactive wastes to a solid, relatively insoluble, thermally stable form is provided and comprises the steps of reacting powdered aluminum silicate clay, e.g., kaolin, bentonite, dickite, halloysite, pyrophyllite, etc., with the sodium nitrate-containing radioactive wastes which have a caustic concentration of about 3 to 7 M at a temperature of 30.degree. C to 100.degree. C to thereby entrap the dissolved radioactive salts in the aluminosilicate matrix. In one embodiment the sodium nitrate-containing, caustic, radioactive liquid waste, such as neutralized Purex-type waste, or salts or oxide produced by evaporation or calcination of these liquid wastes (e.g., anhydrous salt cake) is converted at a temperature within the range of 30.degree. C to 100.degree. C to the solid mineral form-cancrinite having an approximate chemical formula 2(NaAlSiO.sub.4) .sup.. xSalt.sup.. y H.sub.2 O with x = 0.52 and y = 0.68 when the entrapped salt is NaNO.sub.3. In another embodiment the sodium nitrate-containing, caustic, radioactive liquid is reacted with the powdered aluminum silicate clay at a temperature within the range of 30.degree. C to 100.degree. C, the resulting reaction product is air dried eitheras loose powder or molded shapes (e.g., bricks) and then fired at a temperature of at least 600.degree. C to form the solid mineral form-nepheline which has the approximate chemical formula of NaAlSiO.sub.4. The leach rate of the entrapped radioactive salts with distilled water is reduced essentially to that of the aluminosilicate lattice which is very low, e.g., in the range of 10.sup.-.sup.2 to 10.sup.-.sup.4 g/cm.sup.2 -- day for cancrinite and 10.sup.-.sup.3 to 10.sup.-.sup.5 g/cm.sup.2 -- day for nepheline.

An effective assessment of valproate sodium-induced hepatotoxicity with UPLC-MS and (1)HNMR-based metabonomics approach.

PubMed

Huo, Taoguang; Chen, Xi; Lu, Xiumei; Qu, Lianyue; Liu, Yang; Cai, Shuang

2014-10-15

Valproate sodium is one of the most prescribed antiepileptic drugs. However, valproate sodium has various side effects, especially its toxicity on liver. Current markers for toxicity reflect mostly the late stages of tissue damage; thus, more efficient methods for toxicity evaluation are desired. To evaluate the toxicity of valproate sodium on liver, we performed both UPLC-MS and (1)HNMR-based metabonomics analysis of serum samples from 34 epileptic patients (age: 42.0±18.6, 18 male/16 female) after valproate sodium treatment. Compared to conventional markers, the serum metabolic profiles provided clear distinction of the valproate sodium induced normal liver function and abnormal liver function in epileptic patients. Through multivariate statistical analysis, we identified marker metabolites associated with the hepatotoxicity induced by valproate sodium, such as glucose, lactate, acetoacetate, VLDL/LDL, lysophosphatidylcholines, phosphatidylcholines, choline, creatine, amino acids, N-acetyl glycoprotein, pyruvate and uric acid. This metabonomics approach may provide effective way to evaluate the valproate sodium-induced toxicity in a manner that can complement current measures. This approach is expected to find broader application in other drug-induced toxicity assessment. Copyright © 2014 Elsevier B.V. All rights reserved.

The role of historical fire disturbance in the carbon dynamics of the pan-boreal region: A process-based analysis

USGS Publications Warehouse

Balshi, M. S.; McGuire, A.D.; Zhuang, Q.; Melillo, J.; Kicklighter, D.W.; Kasischke, E.; Wirth, C.; Flannigan, M.; Harden, J.; Clein, Joy S.; Burnside, T.J.; McAllister, J.; Kurz, W.A.; Apps, M.; Shvidenko, A.

2007-01-01

Wildfire is a common occurrence in ecosystems of northern high latitudes, and changes in the fire regime of this region have consequences for carbon feedbacks to the climate system. To improve our understanding of how wildfire influences carbon dynamics of this region, we used the process-based Terrestrial Ecosystem Model to simulate fire emissions and changes in carbon storage north of 45??N from the start of spatially explicit historically recorded fire records in the twentieth century through 2002, and evaluated the role of fire in the carbon dynamics of the region within the context of ecosystem responses to changes in atmospheric CO2 concentration and climate. Our analysis indicates that fire plays an important role in interannual and decadal scale variation of source/sink relationships of northern terrestrial ecosystems and also suggests that atmospheric CO2 may be important to consider in addition to changes in climate and fire disturbance. There are substantial uncertainties in the effects of fire on carbon storage in our simulations. These uncertainties are associated with sparse fire data for northern Eurasia, uncertainty in estimating carbon consumption, and difficulty in verifying assumptions about the representation of fires that occurred prior to the start of the historical fire record. To improve the ability to better predict how fire will influence carbon storage of this region in the future, new analyses of the retrospective role of fire in the carbon dynamics of northern high latitudes should address these uncertainties. Copyright 2007 by the American Geophysical Union.

Application of thermogravimetry-differential thermal analysis (TG-DTA) technique to study the ancient potteries from Vellore dist, Tamilnadu, India

NASA Astrophysics Data System (ADS)

Ravisankar, R.; Naseerutheen, A.; Rajalakshmi, A.; Raja Annamalai, G.; Chandrasekaran, A.

2014-08-01

The characterization of archeological ceramic and pottery can be studied for the determination of firing temperature and the presence of raw materials by thermal analysis. Clay minerals are the main material for the production of ceramic and pottery and show some characteristic reactions such as dehydration, dehydroxylation and transformation. This is key point of criteria for the elucidation of firing temperature and raw material analysis. In the present work, DTA-TG, XRD and EDXRF technique are applied on representative potsherds from Vellore dist., Tamilnadu, India to derive the information about the production technology, raw materials and firing temperature. From the analysis, all the samples were considered to be fired from 800 °C to 900 °C and organic material might be added intestinally as a binder in the preparation of pottery.

Mapping Fire Severity Using Imaging Spectroscopy and Kernel Based Image Analysis

NASA Astrophysics Data System (ADS)

Prasad, S.; Cui, M.; Zhang, Y.; Veraverbeke, S.

2014-12-01

Improved spatial representation of within-burn heterogeneity after wildfires is paramount to effective land management decisions and more accurate fire emissions estimates. In this work, we demonstrate feasibility and efficacy of airborne imaging spectroscopy (hyperspectral imagery) for quantifying wildfire burn severity, using kernel based image analysis techniques. Two different airborne hyperspectral datasets, acquired over the 2011 Canyon and 2013 Rim fire in California using the Airborne Visible InfraRed Imaging Spectrometer (AVIRIS) sensor, were used in this study. The Rim Fire, covering parts of the Yosemite National Park started on August 17, 2013, and was the third largest fire in California's history. Canyon Fire occurred in the Tehachapi mountains, and started on September 4, 2011. In addition to post-fire data for both fires, half of the Rim fire was also covered with pre-fire images. Fire severity was measured in the field using Geo Composite Burn Index (GeoCBI). The field data was utilized to train and validate our models, wherein the trained models, in conjunction with imaging spectroscopy data were used for GeoCBI estimation wide geographical regions. This work presents an approach for using remotely sensed imagery combined with GeoCBI field data to map fire scars based on a non-linear (kernel based) epsilon-Support Vector Regression (e-SVR), which was used to learn the relationship between spectra and GeoCBI in a kernel-induced feature space. Classification of healthy vegetation versus fire-affected areas based on morphological multi-attribute profiles was also studied. The availability of pre- and post-fire imaging spectroscopy data over the Rim Fire provided a unique opportunity to evaluate the performance of bi-temporal imaging spectroscopy for assessing post-fire effects. This type of data is currently constrained because of limited airborne acquisitions before a fire, but will become widespread with future spaceborne sensors such as those on the planned NASA HyspIRI mission.

Dietary sodium intake and overweight and obesity in children and adults: a protocol for a systematic review and meta-analysis.

PubMed

Grimes, Carley A; Bolhuis, Dieuwerke P; He, Feng J; Nowson, Caryl A

2016-01-18

Overweight and obesity in children and adults is a major public health concern. Emerging evidence suggests dietary sodium intake may be associated with obesity. This systematic review and meta-analysis will aim to (i) assess the relation between dietary sodium intake and measures of adiposity in children and adults and (ii) examine the relation between sodium intake and sugar-sweetened beverage (SSB) consumption, which is a known risk factor for obesity. An electronic search will be conducted using Medline Complete, CINAHL, Scopus, Embase and Cochrane central register of controlled trials (CENTRAL). The search strategy will identify published peer-reviewed articles that report on dietary sodium and either a marker of adiposity or SSB consumption. Only human studies (ages >1 year) in English will be included, and no limits will be placed on publication date. No restrictions will be placed on the method of sodium intake assessment. Cross-sectional, prospective studies, and randomised controlled trials with a duration of ≥ 3 months will be included. Studies with participants with renal disease, cancer, type 1 diabetes or heart failure or who are pregnant will be excluded. To assess the quality of studies, the Cochrane's Collaboration tool for assessing risk of bias in randomised trials will be used for randomised controlled trials (RCTs), and the modified Newcastle-Ottawa Scale will be used for cross-sectional and prospective studies. Meta-analysis will be used to assess the relation of sodium intake with two primary outcomes: (i) BMI and body weight in adults and BMI z-score in children and (ii) weight category (i.e. healthy weight vs. overweight/obese). For any outcomes in which meta-analysis is not possible, we will present data as a systematic review. Findings will be grouped and reported separately for children and adolescents (ages 1-17 years) and adults (ages >18 years). This review and meta-analysis will provide insight into the relation between dietary sodium intake and overweight and obesity. This information can be used to inform public health policies which target population sodium consumption. Prospero CRD42015016440.

Ten-Year Analysis of the Forest Fire Smoke in the Russian Far East

DTIC Science & Technology

2005-07-25

factor when we monitor the environmental pollution by wide distribution of fire smoke. We examined the relation among the forest fire, smoke, and precipitation, and showed the importance role of precipitation.

Fire assisted pastoralism vs. sustainable forestry--the implications of missing markets for carbon in determining optimal land use in the wet-dry tropics of Australia.

PubMed

Ockwell, David; Lovett, Jon C

2005-04-01

Using Cape York Peninsula, Queensland, Australia as a case study, this paper combines field sampling of woody vegetation with cost-benefit analysis to compare the social optimality of fire-assisted pastoralism with sustainable forestry. Carbon sequestration is estimated to be significantly higher in the absence of fire. Integration of carbon sequestration benefits for mitigating future costs of climate change into cost-benefit analysis demonstrates that sustainable forestry is a more socially optimal land use than fire-assisted pastoralism. Missing markets for carbon, however, imply that fire-assisted pastoralism will continue to be pursued in the absence of policy intervention. Creation of markets for carbon represents a policy solution that has the potential to drive land use away from fire-assisted pastoralism towards sustainable forestry and environmental conservation.

ENSO controls interannual fire activity in southeast Australia

NASA Astrophysics Data System (ADS)

Mariani, M.; Fletcher, M.-S.; Holz, A.; Nyman, P.

2016-10-01

El Niño-Southern Oscillation (ENSO) is the main mode controlling the variability in the ocean-atmosphere system in the South Pacific. While the ENSO influence on rainfall regimes in the South Pacific is well documented, its role in driving spatiotemporal trends in fire activity in this region has not been rigorously investigated. This is particularly the case for the highly flammable and densely populated southeast Australian sector, where ENSO is a major control over climatic variability. Here we conduct the first region-wide analysis of how ENSO controls fire activity in southeast Australia. We identify a significant relationship between ENSO and both fire frequency and area burnt. Critically, wavelet analyses reveal that despite substantial temporal variability in the ENSO system, ENSO exerts a persistent and significant influence on southeast Australian fire activity. Our analysis has direct application for developing robust predictive capacity for the increasingly important efforts at fire management.

Analysis of volatiles in fire debris by combination of activated charcoal strips (ACS) and automated thermal desorption-gas chromatography-mass spectrometry (ATD/GC-MS).

PubMed

Martin Fabritius, Marie; Broillet, Alain; König, Stefan; Weinmann, Wolfgang

2018-06-04

Adsorption of volatiles in gaseous phase to activated charcoal strip (ACS) is one possibility for the extraction and concentration of ignitable liquid residues (ILRs) from fire debris in arson investigations. Besides liquid extraction using carbon dioxide or hexane, automated thermo-desorption can be used to transfer adsorbed residues to direct analysis by gas chromatography-mass spectrometry (GC-MS). We present a fire debris analysis work-flow with headspace adsorption of volatiles onto ACS and subsequent automated thermo-desorption (ATD) GC-MS analysis. Only a small portion of the ACS is inserted in the ATD tube for thermal desorption coupled to GC-MS, allowing for subsequent confirmation analysis with another portion of the same ACS. This approach is a promising alternative to the routinely used ACS method with solvent extraction of retained volatiles, and the application to fire debris analysis is demonstrated. Copyright © 2018 Elsevier B.V. All rights reserved.

Stratigraphic charcoal analysis on petrographic thin sections: Application to fire history in northwestern Minnesota

NASA Astrophysics Data System (ADS)

Clark, James S.

1988-07-01

Results of stratigraphic charcoal analysis from thin sections of varved lake sediments have been compared with fire scars on red pine trees in northwestern Minnesota to determine if charcoal data accurately reflect fire regimes. Pollen and opaque-spherule analyses were completed from a short core to confirm that laminations were annual over the last 350 yr. A good correspondence was found between fossil-charcoal and fire-scar data. Individual fires could be identified as specific peaks in the charcoal curves, and times of reduced fire frequency were reflected in the charcoal data. Charcoal was absent during the fire-suppression era from 1920 A.D. to the present. Distinct charcoal maxima from 1864 to 1920 occurred at times of fire within the lake catchment. Fire was less frequent during the 19th century, and charcoal was substantially less abundant. Fire was frequent from 1760 to 1815, and charcoal was abundant continuously. Fire scars and fossil charcoal indicate that fires did not occur during 1730-1750 and 1670-1700. Several fires occurred from 1640 to 1670 and 1700 to 1730. Charcoal counted from pollen preparations in the area generally do not show this changing fire regime. Simulated "sampling" of the thin-section data in a fashion comparable to pollen-slide methods suggests that sampling alone is not sufficient to account for differences between the two methods. Integrating annual charcoal values in this fashion still produced much higher resolution than the pollen-slide method, and the postfire suppression decline of charcoal characteristic of my method (but not of pollen slides) is still evident. Consideration of the differences in size of fragments counted by the two methods is necessary to explain charcoal representation in lake sediments.

Decadal time-scale monitoring of forest fires in Similipal Biosphere Reserve, India using remote sensing and GIS.

PubMed

Saranya, K R L; Reddy, C Sudhakar; Rao, P V V Prasada; Jha, C S

2014-05-01

Analyzing the spatial extent and distribution of forest fires is essential for sustainable forest resource management. There is no comprehensive data existing on forest fires on a regular basis in Biosphere Reserves of India. The present work have been carried out to locate and estimate the spatial extent of forest burnt areas using Resourcesat-1 data and fire frequency covering decadal fire events (2004-2013) in Similipal Biosphere Reserve. The anomalous quantity of forest burnt area was recorded during 2009 as 1,014.7 km(2). There was inconsistency in the fire susceptibility across the different vegetation types. The spatial analysis of burnt area shows that an area of 34.2 % of dry deciduous forests, followed by tree savannah, shrub savannah, and grasslands affected by fires in 2013. The analysis based on decadal time scale satellite data reveals that an area of 2,175.9 km(2) (59.6 % of total vegetation cover) has been affected by varied rate of frequency of forest fires. Fire density pattern indicates low count of burnt area patches in 2013 estimated at 1,017 and high count at 1,916 in 2004. An estimate of fire risk area over a decade identifies 12.2 km(2) is experiencing an annual fire damage. Summing the fire frequency data across the grids (each 1 km(2)) indicates 1,211 (26 %) grids are having very high disturbance regimes due to repeated fires in all the 10 years, followed by 711 grids in 9 years and 418 in 8 years and 382 in 7 years. The spatial database offers excellent opportunities to understand the ecological impact of fires on biodiversity and is helpful in formulating conservation action plans.

Climate Change and Mountain Community Fire Management in the Cordillera Blanca, Peru

NASA Astrophysics Data System (ADS)

All, J.; Medler, M.; Cole, R. J.; Arques, S.; Schmitt, C. G.

2014-12-01

In the central Andes of Peru, climate change is altering fire risk through changes in local meteorology and fuel loading. Greater moisture and favorable growing conditions are increasing vegetative productivity, which in turn increases fuel loads. This process is accentuated during El Nino events and potentially results in increased fire occurrence and frequency during relatively dry La Nina events. Park officials are concerned about the ramification of the changes on local ecology and tourist use of the resources. However, using a time-series of two different products from the MODIS Terra and Aqua platforms (Active Fire and Burned Area), TRMM 3B43 precipitation data, and Multivariate ENSO Index data we document fire occurrence and extent from 2000 to 2010 and our analysis indicates that fires are burning exclusively during winter months when there are no natural ignition sources. Globally, fire is used in conjunction with grazing to improve the regeneration and yield of grasses. During our interviews, locals claimed to only set fires in the buffer zone outside of the park, but our analysis indicates that the buffer zone rarely burns and that most fires begin within the park and only occasionally move into the buffer zones. Additionally, we determined that although this is small-scale fire activity every year, overall fire is having a very minor effect on local systems. The park service must develop programs to work with local grazing stakeholders to better limit the impacts of fire, while also address the negative perceptions from tourists in the future. In this instance, fire perception and fire reality are not the same and the challenge for resource managers is how to reconcile these two factors in order to more effectively manage the parklands.

An experimental evaluation of fire history reconstruction using dendrochronology in white oak (Quercus alba)

Treesearch

Ryan W. McEwan; Todd F. Hutchinson; Robert D. Ford; Brian C. McCarthy

2007-01-01

Dendrochronological analysis of fire scars on tree cross sections has been critically important for understanding historical fire regimes and has influenced forest management practices. Despite its value as a tool for understanding historical ecosystems, tree-ring-based fire history reconstruction has rarely been experimentally evaluated. To examine the efficacy of...

Fire fighting aboard ships. Volume 1: Hazard analysis and behavior of combustible materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stavitskiy, M.G.; Kortunov, M.F.; Sidoryuk, V.M.

1983-01-01

The volume zeros in on fire hazards on ships afloat or under construction/repair. It examines fire hazards peculiar to ships carrying particular cargoes, such as dry-cargo ships, tankers, and factory and fishing vessels. This volume examines specific features of fire-fighting equipment, along with the thermal behavior of materials used in shipbuilding.

Study of lithium extraction from brine water, Bledug Kuwu, Indonesia by the precipitation series of oxalic acid and carbonate sodium

NASA Astrophysics Data System (ADS)

Sulistiyono, Eko; Lalasari, Latifa Hanum; Mayangsari, W.; Prasetyo, A. B.

2018-05-01

Lithium is one of the key elements in the development of batteries for electric car applications. Currently, the resources of the world's lithium are derived from brine water and lithium mineral based on spodumene rock. Indonesia which is located in the area of the ring of fire, has potential brine water resources in some area, such as brine water from Bledug Kuwu, Central Java that used in this research. The purposes of this research are to characterize brine water, Bledug Kuwu and to investigate the influence of chemical solvents on Li, Na, K, Ca, Mg, Al, B ion precipitation from brine water. This research was done with 2 times the process of chemical precipitation that runs series as follows: 5 liters of brine water were chemically precipitated using 400 ml of 12.43 N oxalic acid and followed by chemical precipitation using 400 mL of 7.07 N sodium carbonate solutions. Evaporation and filtration processes were also done twice in an effort to separate white precipitate and filtrate. The filtrate was analyzed by ICP-OES and white precipitates (salts) were analyzed by SEM, XRD, and XRF. The result shows that oxalate precipitation process extracted 32.24% Al, 23.42% B, 22.43% Ca, 14.26% Fe, 3.21 % K, 9.86% Na and 14.26% Li, the following process by carbonate precipitation process extracted 98.86% Mg, 73% Ca, 22.53% Li, 82.04% Al, 14.38% B, 12.50% K, 2.27% Na. There is 63.21% lithium is not extracted from the series process. The SEM analysis shows that the structure of granules on the precipitated salts by oxalic acid form gentle cubic-shaped solid. In the other hand, oxalate precipitation followed by sodium carbonate has various particle sizes and the shape of crystals is fragments, prism and cube look like magnesium carbonate, calcium chloride, and calcite's crystal respectively. This is in accordance with XRD analysis that phases of whewellite (CaC2O4.H2O), disodium oxalate (Na2C2O4), magnesite (MgCO3), calcium lithium aluminum (Al1.19 Ca1Li0.81), dolomite (CaCO3.MgCO3) appear in salt precipitated by oxalic acid. For salt precipitated by oxalic acid and sodium carbonate look peaks of dolomite and calcite (CaCO3) as main components. Lithium carbonate (Li2CO3) and calcium chloride (CaCl2) also are described with high peak intensity in this precipitation. A series of precipitation process shows that lithium is precipitated together with calcium, aluminum, and carbonate.

Therapeutic concentrations of varenicline in the presence of nicotine increase action potential firing in human adrenal chromaffin cells.

PubMed

Hone, Arik J; Michael McIntosh, J; Rueda-Ruzafa, Lola; Passas, Juan; de Castro-Guerín, Cristina; Blázquez, Jesús; González-Enguita, Carmen; Albillos, Almudena

2017-01-01

Varenicline is a nicotinic acetylcholine receptor (nAChR) agonist used to treat nicotine addiction, but a live debate persists concerning its mechanism of action in reducing nicotine consumption. Although initially reported as α4β2 selective, varenicline was subsequently shown to activate other nAChR subtypes implicated in nicotine addiction including α3β4. However, it remains unclear whether activation of α3β4 nAChRs by therapeutically relevant concentrations of varenicline is sufficient to affect the behavior of cells that express this subtype. We used patch-clamp electrophysiology to assess the effects of varenicline on native α3β4* nAChRs (asterisk denotes the possible presence of other subunits) expressed in human adrenal chromaffin cells and compared its effects to those of nicotine. Varenicline and nicotine activated α3β4* nAChRs with EC 50 values of 1.8 (1.2-2.7) μM and 19.4 (11.1-33.9) μM, respectively. Stimulation of adrenal chromaffin cells with 10 ms pulses of 300 μM acetylcholine (ACh) in current-clamp mode evoked sodium channel-dependent action potentials (APs). Under these conditions, perfusion of 50 or 100 nM varenicline showed very little effect on AP firing compared to control conditions (ACh stimulation alone), but at higher concentrations (250 nM) varenicline increased the number of APs fired up to 436 ± 150%. These results demonstrate that therapeutic concentrations of varenicline are unlikely to alter AP firing in chromaffin cells. In contrast, nicotine showed no effect on AP firing at any of the concentrations tested (50, 100, 250, and 500 nM). However, perfusion of 50 nM nicotine simultaneously with 100 nM varenicline increased AP firing by 290 ± 104% indicating that exposure to varenicline and nicotine concurrently may alter cellular behavior such as excitability and neurotransmitter release. © 2016 International Society for Neurochemistry.

Secondary Fire Analysis.

DTIC Science & Technology

1981-09-01

of wood frame and brick veneer, slab on grade construction), killed 33, injured more than 1,000, derailed a train, destroyed 4,000 cars, uprooted most... of a nuclear detonation) in or near structures, with emphasis on critical facil- ities and industries. Assessment of the potential for secondary fires...and/or 517 East Dayshore, Redwood City, CA 94063 DistI pial (DETACHABLE SUMMARY) SECONDARY FIRE ANALYSIS This report presents the results of a

Enhanced sulfidation xanthate flotation of malachite using ammonium ions as activator.

PubMed

Wu, Dandan; Ma, Wenhui; Mao, Yingbo; Deng, Jiushuai; Wen, Shuming

2017-05-18

In this study, ammonium ion was used to enhance the sulfidation flotation of malachite. The effect of ammonium ion on the sulfidation flotation of malachite was investigated using microflotation test, inductively coupled plasma (ICP) analysis, zeta potential measurements, and scanning electron microscope analysis (SEM). The results of microflotation test show that the addition of sodium sulfide and ammonium sulfate resulted in better sulfidation than the addition of sodium sulfide alone. The results of ICP analysis indicate that the dissolution of enhanced sulfurized malachite surface is significantly decreased. Zeta potential measurements indicate that a smaller isoelectric point value and a large number of copper-sulfide films formed on the malachite surface by enhancing sulfidation resulted in a large amount of sodium butyl xanthate absorbed onto the enhanced sulfurized malachite surface. EDS semi-quantitative analysis and XPS analysis show that malachite was easily sulfurized by sodium sulfide with ammonium ion. These results show that the addition of ammonium ion plays a significant role in the sulfidation of malachite and results in improved flotation performance.

Fire Risk Assessment of Some Indian Coals Using Radial Basis Function (RBF) Technique

NASA Astrophysics Data System (ADS)

Nimaje, Devidas; Tripathy, Debi Prasad

2017-04-01

Fires, whether surface or underground, pose serious and environmental problems in the global coal mining industry. It is causing huge loss of coal due to burning and loss of lives, sterilization of coal reserves and environmental pollution. Most of the instances of coal mine fires happening worldwide are mainly due to the spontaneous combustion. Hence, attention must be paid to take appropriate measures to prevent occurrence and spread of fire. In this paper, to evaluate the different properties of coals for fire risk assessment, forty-nine in situ coal samples were collected from major coalfields of India. Intrinsic properties viz. proximate and ultimate analysis; and susceptibility indices like crossing point temperature, flammability temperature, Olpinski index and wet oxidation potential method of Indian coals were carried out to ascertain the liability of coal to spontaneous combustion. Statistical regression analysis showed that the parameters of ultimate analysis provide significant correlation with all investigated susceptibility indices as compared to the parameters of proximate analysis. Best correlated parameters (ultimate analysis) were used as inputs to the radial basis function network model. The model revealed that Olpinski index can be used as a reliable method to assess the liability of Indian coals to spontaneous combustion.

Combined target factor analysis and Bayesian soft-classification of interference-contaminated samples: forensic fire debris analysis.

PubMed

Williams, Mary R; Sigman, Michael E; Lewis, Jennifer; Pitan, Kelly McHugh

2012-10-10

A bayesian soft classification method combined with target factor analysis (TFA) is described and tested for the analysis of fire debris data. The method relies on analysis of the average mass spectrum across the chromatographic profile (i.e., the total ion spectrum, TIS) from multiple samples taken from a single fire scene. A library of TIS from reference ignitable liquids with assigned ASTM classification is used as the target factors in TFA. The class-conditional distributions of correlations between the target and predicted factors for each ASTM class are represented by kernel functions and analyzed by bayesian decision theory. The soft classification approach assists in assessing the probability that ignitable liquid residue from a specific ASTM E1618 class, is present in a set of samples from a single fire scene, even in the presence of unspecified background contributions from pyrolysis products. The method is demonstrated with sample data sets and then tested on laboratory-scale burn data and large-scale field test burns. The overall performance achieved in laboratory and field test of the method is approximately 80% correct classification of fire debris samples. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laurinat, J.; Kesterson, M.; Hensel, S.

The documented safety analysis for the Savannah River Site evaluates the consequences of a postulated 1000 °C fire in a glovebox. The radiological dose consequences for a pressurized release of plutonium oxide powder during such a fire depend on the maximum pressure that is attained inside the oxide storage vial. To enable evaluation of the dose consequences, pressure transients and venting flow rates have been calculated for exposure of the storage vial to the fire. A standard B vial with a capacity of approximately 8 cc was selected for analysis. The analysis compares the pressurization rate from heating and evaporationmore » of moisture adsorbed onto the plutonium oxide contents of the vial with the pressure loss due to venting of gas through the threaded connection between the vial cap and body. Tabulated results from the analysis include maximum pressures, maximum venting velocities, and cumulative vial volumes vented during the first 10 minutes of the fire transient. Results are obtained for various amounts of oxide in the vial, various amounts of adsorbed moisture, different vial orientations, and different surface fire exposures.« less

Directory of workers in the fire field

NASA Technical Reports Server (NTRS)

Kuvshinoff, B. W.; Mcleod, S. B.; Katz, R. G.

1973-01-01

A directory was compiled to provide a list of workers engaged in fire research, their addresses and affiliations, and their principal fields of activity. The initial criteria for the selection of names for the directory are recent contributions to fire literature, teaching of subjects relevant to fire science, or participation in or support of fire research programs. With some exceptions, fire service personnel and fire protection engineers were excluded because directories already exist for these professionals. Also excluded are investigators engaged principally in studies of propulsion, combustion, and explosion phenomena, because these areas of study are somewhat aside from the main focus of fire research. For purposes of the directory, fire science is taken to be the body of knowledge, art, and skill related to the investigation, analysis, and interpretation of the phenomena of unwanted fires and the evaluation of materials methods, systems, and equipment related to fire safety, prevention, detection, and suppression.

Voltage gating by molecular subunits of Na+ and K+ ion channels: higher-dimensional cubic kinetics, rate constants, and temperature.

PubMed

Fohlmeister, Jürgen F

2015-06-01

The structural similarity between the primary molecules of voltage-gated Na and K channels (alpha subunits) and activation gating in the Hodgkin-Huxley model is brought into full agreement by increasing the model's sodium kinetics to fourth order (m(3) → m(4)). Both structures then virtually imply activation gating by four independent subprocesses acting in parallel. The kinetics coalesce in four-dimensional (4D) cubic diagrams (16 states, 32 reversible transitions) that show the structure to be highly failure resistant against significant partial loss of gating function. Rate constants, as fitted in phase plot data of retinal ganglion cell excitation, reflect the molecular nature of the gating transitions. Additional dimensions (6D cubic diagrams) accommodate kinetically coupled sodium inactivation and gating processes associated with beta subunits. The gating transitions of coupled sodium inactivation appear to be thermodynamically irreversible; response to dielectric surface charges (capacitive displacement) provides a potential energy source for those transitions and yields highly energy-efficient excitation. A comparison of temperature responses of the squid giant axon (apparently Arrhenius) and mammalian channel gating yields kinetic Q10 = 2.2 for alpha unit gating, whose transitions are rate-limiting at mammalian temperatures; beta unit kinetic Q10 = 14 reproduces the observed non-Arrhenius deviation of mammalian gating at low temperatures; the Q10 of sodium inactivation gating matches the rate-limiting component of activation gating at all temperatures. The model kinetics reproduce the physiologically large frequency range for repetitive firing in ganglion cells and the physiologically observed strong temperature dependence of recovery from inactivation. Copyright © 2015 the American Physiological Society.

Safinamide Differentially Modulates In Vivo Glutamate and GABA Release in the Rat Hippocampus and Basal Ganglia.

PubMed

Morari, Michele; Brugnoli, Alberto; Pisanò, Clarissa Anna; Novello, Salvatore; Caccia, Carla; Melloni, Elsa; Padoani, Gloria; Vailati, Silvia; Sardina, Marco

2018-02-01

Safinamide has been recently approved as an add-on to levodopa therapy for Parkinson disease. In addition to inhibiting monoamine oxidase type B, it blocks sodium channels and modulates glutamate (Glu) release in vitro. Since this property might contribute to the therapeutic action of the drug, we undertook the present study to investigate whether safinamide inhibits Glu release also in vivo and whether this effect is consistent across different brain areas and is selective for glutamatergic neurons. To this aim, in vivo microdialysis was used to monitor the spontaneous and veratridine-induced Glu and GABA release in the hippocampus and basal ganglia of naive, awake rats. Brain levels of safinamide were measured as well. To shed light on the mechanisms underlying the effect of safinamide, sodium currents were measured by patch-clamp recording in rat cortical neurons. Safinamide maximally inhibited the veratridine-induced Glu and GABA release in hippocampus at 15 mg/kg, which reached free brain concentrations of 1.89-1.37 µ M. This dose attenuated veratridine-stimulated Glu (but not GABA) release in subthalamic nucleus, globus pallidus, and substantia nigra reticulata, but not in striatum. Safinamide was ineffective on spontaneous neurotransmitter release. In vitro, safinamide inhibited sodium channels, showing a greater affinity at depolarized (IC 50 = 8 µ M) than at resting (IC 50 = 262 µ M) potentials. We conclude that safinamide inhibits in vivo Glu release from stimulated nerve terminals, likely via blockade of sodium channels at subpopulations of neurons with specific firing patterns. These data are consistent with the anticonvulsant and antiparkinsonian actions of safinamide and provide support for the nondopaminergic mechanism of its action. Copyright © 2018 The Author(s).

Changes in central sodium and not osmolarity or lactate induce panic-like responses in a model of panic disorder.

PubMed

Molosh, Andre I; Johnson, Philip L; Fitz, Stephanie D; Dimicco, Joseph A; Herman, James P; Shekhar, Anantha

2010-05-01

Panic disorder is a severe anxiety disorder characterized by recurrent panic attacks that can be consistently provoked with intravenous (i.v.) infusions of hypertonic (0.5 M) sodium lactate (NaLac), yet the mechanism/CNS site by which this stimulus triggers panic attacks is unclear. Chronic inhibition of GABAergic synthesis in the dorsomedial hypothalamus/perifornical region (DMH/PeF) of rats induces a vulnerability to panic-like responses after i.v. infusion of 0.5 M NaLac, providing an animal model of panic disorder. Using this panic model, we previously showed that inhibiting the anterior third ventricle region (A3Vr; containing the organum vasculosum lamina terminalis, the median preoptic nucleus, and anteroventral periventricular nucleus) attenuates cardiorespiratory and behavioral responses elicited by i.v. infusions of NaLac. In this study, we show that i.v. infusions of 0.5 M NaLac or sodium chloride, but not iso-osmolar D-mannitol, increased 'anxiety' (decreased social interaction) behaviors, heart rate, and blood pressure responses. Using whole-cell patch-clamp preparations, we also show that bath applications of NaLac (positive control), but not lactic acid (lactate stimulus) or D-mannitol (osmolar stimulus), increases the firing rates of neurons in the A3Vr, which are retrogradely labeled from the DMH/PeF and which are most likely glutamatergic based on a separate study using retrograde tracing from the DMH/PeF in combination with in situ hybridization for vesicular glutamate transporter 2. These data show that hypertonic sodium, but not hyper-osmolarity or changes in lactate, is the key stimulus that provokes panic attacks in panic disorder, and is consistent with human studies.

Assessment of Sodium and Potassium Intake by 24 h Urinary Excretion in a Healthy Mexican Cohort.

PubMed

Vallejo, Maite; Colín-Ramírez, Eloisa; Rivera Mancía, Susana; Cartas Rosado, Raúl; Madero, Magdalena; Infante Vázquez, Oscar; Vargas-Barrón, Jesús

2017-02-01

A high dietary sodium intake and a low potassium intake are associated with adverse cardiovascular health. Data on these nutrients consumption in Mexico is limited. The aim of this study was to assess sodium and potassium intake by 24 h urinary excretion in a clinically healthy Mexican population. We additionally explored their association with blood pressure. 711 clinically healthy participants aged 20-50 years old recruited in the Tlalpan 2020 cohort from September 2014-December 2015, were included in this cross-sectional analysis. All participants provided a 24 h urine sample and underwent anthropometric, biochemical, and blood pressure evaluations. Univariate and multivariate linear regression analyses were used to assess the association of urinary sodium, potassium, and Na/K ratio with blood pressure. Mean (95% confidence interval [CI]) urinary sodium and potassium in the overall population was 3150.1 (3054.2-3246.0) mg/d and 1909.5 (1859.3-1959.6) mg/d, respectively. Overall, only 121 (17%) met the WHO recommendation for sodium intake (<2000 mg/d) and 16 (2.3%) met the goal for potassium intake (≥3510 mg/d). Urinary sodium (β coefficient 1.3, 95% CI: 0.7, 1.8, p <0.001) and potassium (β coefficient 2.1, 95% CI: 1.0, 3.2, p <0.001) were found to be associated with systolic blood pressure in the univariate analysis but not in the multivariate analysis. Sodium intake was higher and potassium intake was lower than the WHO recommendations in this healthy Mexican population. Sodium and potassium intakes were not associated with blood pressure at the mean levels of intake observed in this population, after adjusting for key variables. Copyright © 2017 IMSS. Published by Elsevier Inc. All rights reserved.

Fire safety in transit systems fault tree analysis

DOT National Transportation Integrated Search

1981-09-01

Fire safety countermeasures applicable to transit vehicles are identified and evaluated. This document contains fault trees which illustrate the sequences of events which may lead to a transit-fire related casualty. A description of the basis for the...

Polarographic Analysis of Primers

DTIC Science & Technology

1945-03-30

also in 0.5 M sodium acetate, ammonium acetate, aoetlc acid, sodium acetate plus acetic acid, and sodium tartrate plus tartaric &cid. In all these...potassium tartrate end potassium hydroxide (4 M pot as; ^ura hydroxide plus 2 11 potassium tartrate , the anodic sulfide tjave is well defined, but the...our experiments. Solutions of "synthetic" stibnite, formed by adding stoichinmetric amounts of potassium antimony! tartrate and sodium sulfide to

Determination of Ignitable Liquids in Fire Debris: Direct Analysis by Electronic Nose

PubMed Central

Ferreiro-González, Marta; Barbero, Gerardo F.; Palma, Miguel; Ayuso, Jesús; Álvarez, José A.; Barroso, Carmelo G.

2016-01-01

Arsonists usually use an accelerant in order to start or accelerate a fire. The most widely used analytical method to determine the presence of such accelerants consists of a pre-concentration step of the ignitable liquid residues followed by chromatographic analysis. A rapid analytical method based on headspace-mass spectrometry electronic nose (E-Nose) has been developed for the analysis of Ignitable Liquid Residues (ILRs). The working conditions for the E-Nose analytical procedure were optimized by studying different fire debris samples. The optimized experimental variables were related to headspace generation, specifically, incubation temperature and incubation time. The optimal conditions were 115 °C and 10 min for these two parameters. Chemometric tools such as hierarchical cluster analysis (HCA) and linear discriminant analysis (LDA) were applied to the MS data (45–200 m/z) to establish the most suitable spectroscopic signals for the discrimination of several ignitable liquids. The optimized method was applied to a set of fire debris samples. In order to simulate post-burn samples several ignitable liquids (gasoline, diesel, citronella, kerosene, paraffin) were used to ignite different substrates (wood, cotton, cork, paper and paperboard). A full discrimination was obtained on using discriminant analysis. This method reported here can be considered as a green technique for fire debris analyses. PMID:27187407

Critical wind velocity for arresting upwind gas and smoke dispersion induced by near-wall fire in a road tunnel.

PubMed

Hu, L H; Peng, W; Huo, R

2008-01-15

In case of a tunnel fire, toxic gas and smoke particles released are the most fatal contaminations. It is important to supply fresh air from the upwind side to provide a clean and safe environment upstream from the fire source for people evacuation. Thus, the critical longitudinal wind velocity for arresting fire induced upwind gas and smoke dispersion is a key criteria for tunnel safety design. Former studies and thus, the models built for estimating the critical wind velocity are all arbitrarily assuming that the fire takes place at the centre of the tunnel. However, in many real cases in road tunnels, the fire originates near the sidewall. The critical velocity of a near-wall fire should be different with that of a free-standing central fire due to their different plume entrainment process. Theoretical analysis and CFD simulation were performed in this paper to estimate the critical velocity for the fire near the sidewall. Results showed that when fire originates near the sidewall, it needs larger critical velocity to arrest the upwind gas and smoke dispersion than when fire at the centre. The ratio of critical velocity of a near-wall fire to that of a central fire was ideally estimated to be 1.26 by theoretical analysis. Results by CFD modelling showed that the ratio decreased with the increase of the fire size till near to unity. The ratio by CFD modelling was about 1.18 for a 500kW small fire, being near to and a bit lower than the theoretically estimated value of 1.26. However, the former models, including those of Thomas (1958, 1968), Dangizer and Kenndey (1982), Oka and Atkinson (1995), Wu and Barker (2000) and Kunsch (1999, 2002), underestimated the critical velocity needed for a fire near the tunnel sidewall.

Object-based Forest Fire Analysis for Pedrógão Grande Fire Using Landsat 8 OLI and Sentinel-2A Imagery

NASA Astrophysics Data System (ADS)

Tonbul, H.; Kavzoglu, T.

2017-12-01

Forest fires are among the most important natural disasters with the damage to the natural habitat and human-life. Mapping damaged forest fires is crucial for assessing ecological effects caused by fire, monitoring land cover changes and modeling atmospheric and climatic effects of fire. In this context, satellite data provides a great advantage to users by providing a rapid process of detecting burning areas and determining the severity of fire damage. Especially, Mediterranean ecosystems countries sets the suitable conditions for the forest fires. In this study, the determination of burnt areas of forest fire in Pedrógão Grande region of Portugal occurred in June 2017 was carried out using Landsat 8 OLI and Sentinel-2A satellite images. The Pedrógão Grande fire was one of the largest fires in Portugal, more than 60 people was killed and thousands of hectares were ravaged. In this study, four pairs of pre-fire and post-fire top of atmosphere (TOA) and atmospherically corrected images were utilized. The red and near infrared (NIR) spectral bands of pre-fire and post-fire images were stacked and multiresolution segmentation algorithm was applied. In the segmentation processes, the image objects were generated with estimated optimum homogeneity criteria. Using eCognition software, rule sets have been created to distinguish unburned areas from burned areas. In constructing the rule sets, NDVI threshold values were determined pre- and post-fire and areas where vegetation loss was detected using the NDVI difference image. The results showed that both satellite images yielded successful results for burned area discrimination with a very high degree of consistency in terms of spatial overlap and total burned area (over 93%). Object based image analysis (OBIA) was found highly effective in delineation of burnt areas.

Studies for Io's extended atmosphere and neutral clouds and their impact on the local satellite atmosphere and on the planetary magnetosphere

NASA Technical Reports Server (NTRS)

Smyth, William H.

1993-01-01

The research performed in this project is divided in two main investigations: (1) the synthesis and analysis of a collection of independent observations for Io's sodium corona, its sodium extended atmosphere, and the sodium cloud, and (2) the analysis of a (System III longitude correlated) space-time 'bite-out' near western elongation in the 1981 sodium cloud images from the JPL Table Mountain Sodium Cloud Data Set. For the first investigation, modeling analysis of the collective observed spatial profiles has shown that they are reproduced by adopting at Io's exobase a modified sputtering flux speed distribution function which is peaked near 0.5 km/s and has a small high-speed (15-20 km/s) nonisotropic component. The nonisotropic high-speed component is consistent with earlier modeling of the trailing directional feature. For the second investigation, modeling analysis of the 'bite-out' observed near western elongation (but not eastern elongation) has shown that it is reproduced in model calculation by adopting a plasma torus description for the sodium lifetime that is inherently asymmetric in System III longitudes of the active sector and that also has an east-west asymmetry. The east-west and System III longitude asymmetries were determined from independent observations for the plasma torus in 1981. The presence of the 'bite-out' feature only near western elongation may be understood in terms of the relative value for sodium of its lifetime and its transport time through the System III enhanced plasma torus region.

Development of lacosamide for the treatment of partial-onset seizures

PubMed Central

Doty, Pamela; Hebert, David; Mathy, Francois-Xavier; Byrnes, William; Zackheim, James; Simontacchi, Kelly

2013-01-01

Lacosamide is an antiepileptic drug (AED) available in multiple formulations that was first approved in 2008 as adjunctive therapy for partial-onset seizures (POS) in adults. Unlike traditional sodium channel blockers affecting fast inactivation, lacosamide selectively enhances sodium channel slow inactivation. This mechanism of action results in stabilization of hyperexcitable neuronal membranes, inhibition of neuronal firing, and reduction in long-term channel availability without affecting physiological function. Lacosamide has a well-characterized and favorable pharmacokinetic profile, including a fast absorption rate, minimal or no interaction with cytochrome P-450 izoenzymes, and a low potential for drug–drug interactions. Lacosamide clinical development included three placebo-controlled, double-blind, randomized trials conducted in more than 1300 patients, each demonstrating safety and efficacy of lacosamide compared to placebo as adjunctive therapy for adults with POS. The clinical use of lacosamide may broaden, pending results of trials evaluating its use as monotherapy for POS in adults, as treatment for epilepsy in pediatric subjects, and as adjunctive treatment for uncontrolled primary generalized tonic–clonic seizures in those with idiopathic generalized epilepsy. PMID:23859801

Titrimetric Determination of Carbon Dioxide in a Heterogeneous Sample ("Pop Rocks")

NASA Astrophysics Data System (ADS)

Davis, Craig M.; Mauck, Matthew C.

2003-05-01

A traditional exercise in quantitative analysis is the titration of mixtures of sodium hydroxide, sodium carbonate, and sodium bicarbonate. Often, consumer products are studied. A procedure to analyze the total volume of carbon dioxide bubbles in the candy "Pop Rocks" is presented. The popularity of the sample and the simplicity of the procedure make this exercise suitable for a wide variety of students: from non-science majors to chemistry majors in a quantitative analysis course.

Response Mechanism: Blast/Fire Interactions.

DTIC Science & Technology

1983-11-01

A WORK UNIT NUMBERS University of Notre Dame Notre Dame, IN L FEMA WU No. 2564H ItI. CONTROLLING OFFICE NAME AND ADDRESS 12. REPORT DATE Fedqral...Fires 9 Class A Fires 10 Control by Physics or Chemistry? 11 Conments 14 EXTINCTION AND IGNITION 15 Pool Fire 15 Analysis 17 Charring Solid Fire 21...post-explosion time, although its magnitude may make the efforts to control appear futile in the wake of a nuclear attack. There is considerable

Numerical Analysis on Tensile Properties of Grout-filled Splice Sleeve Rebars under ISO 834 Standard Fire

NASA Astrophysics Data System (ADS)

Liu, Yong Jun; Li, Chao; Zhou, When Jun

2018-06-01

This paper presents some numerical simulation results of tensile properties of reinforcing bars spliced by grout-filled coupling sleeves under fire conditions to identify the effect of load ratio on fire resistance time of spliced reinforcing bars, which provide a useful base for predicting structural behaviors of pre-cast reinforced concrete buildings in fires. A spliced rebar system investigated in this paper consists of two equal-diameter steel reinforcing bars with 25mm diameter and a straight coupling sleeve with 50mm outer and 45mm inner diameters. As a result, the thickness of grout between steel bars and sleeves are 20mm. Firstly, the temperature distributions in steel bars connected by grout- filled coupling sleeves exposed to ISO 834 standard fire were calculated utilizing finite element analysis software ANSYS. Secondly, the stress changes in heated steel bars connected by grout-filled coupling sleeves under different constant tensile loads were calculated step by step until the rebar system failed due to fire. Thus, the fire resistant time of rebar spliced by grout-filled coupling sleeves under different axial tensile loads can be determined, further, the relationship between fire resistance time and axial tensile loads ratio can could be obtained. Finally, the fire resistant times versus axial tensile load ratios curve of grout-filled splice sleeve rebars exposed to ISO 834 standard fire is presented.

Areas of Agreement and Disagreement Regarding Ponderosa Pine and Mixed Conifer Forest Fire Regimes: A Dialogue with Stevens et al.

PubMed Central

Odion, Dennis C.; Hanson, Chad T.; Baker, William L.; DellaSala, Dominick A.; Williams, Mark A.

2016-01-01

In a recent PLOS ONE paper, we conducted an evidence-based analysis of current versus historical fire regimes and concluded that traditionally defined reference conditions of low-severity fire regimes for ponderosa pine (Pinus ponderosa) and mixed-conifer forests were incomplete, missing considerable variability in forest structure and fire regimes. Stevens et al. (this issue) agree that high-severity fire was a component of these forests, but disagree that one of the several sources of evidence, stand age from a large number of forest inventory and analysis (FIA) plots across the western USA, support our findings that severe fire played more than a minor role ecologically in these forests. Here we highlight areas of agreement and disagreement about past fire, and analyze the methods Stevens et al. used to assess the FIA stand-age data. We found a major problem with a calculation they used to conclude that the FIA data were not useful for evaluating fire regimes. Their calculation, as well as a narrowing of the definition of high-severity fire from the one we used, leads to a large underestimate of conditions consistent with historical high-severity fire. The FIA stand age data do have limitations but they are consistent with other landscape-inference data sources in supporting a broader paradigm about historical variability of fire in ponderosa and mixed-conifer forests than had been traditionally recognized, as described in our previous PLOS paper. PMID:27195808

Areas of Agreement and Disagreement Regarding Ponderosa Pine and Mixed Conifer Forest Fire Regimes: A Dialogue with Stevens et al.

PubMed

Odion, Dennis C; Hanson, Chad T; Baker, William L; DellaSala, Dominick A; Williams, Mark A

2016-01-01

In a recent PLOS ONE paper, we conducted an evidence-based analysis of current versus historical fire regimes and concluded that traditionally defined reference conditions of low-severity fire regimes for ponderosa pine (Pinus ponderosa) and mixed-conifer forests were incomplete, missing considerable variability in forest structure and fire regimes. Stevens et al. (this issue) agree that high-severity fire was a component of these forests, but disagree that one of the several sources of evidence, stand age from a large number of forest inventory and analysis (FIA) plots across the western USA, support our findings that severe fire played more than a minor role ecologically in these forests. Here we highlight areas of agreement and disagreement about past fire, and analyze the methods Stevens et al. used to assess the FIA stand-age data. We found a major problem with a calculation they used to conclude that the FIA data were not useful for evaluating fire regimes. Their calculation, as well as a narrowing of the definition of high-severity fire from the one we used, leads to a large underestimate of conditions consistent with historical high-severity fire. The FIA stand age data do have limitations but they are consistent with other landscape-inference data sources in supporting a broader paradigm about historical variability of fire in ponderosa and mixed-conifer forests than had been traditionally recognized, as described in our previous PLOS paper.

Near-maximal ECG stress testing and coronary artery disease risk factor analysis in Los Angeles City fire fighters.

PubMed

Barnard, R J; Gardner, G W; Diaco, N V; Kattus, A A

1975-11-01

Near-maximal ECG stress testing and coronary artery disease risk factor analysis including blood pressure, serum cholesterol and smoking habits were conducted on a randomly selected group (N=90) of Los Angeles City Fire Fighters ranging in age from 40 to 59 yrs. The data obtained from the fire fighters were compared to data previously reported for a group of Los Angeles insurance underwriters of the same age range. Only 12% of the fire fighters had cholesterol values greater than 260 mg% while 18% of the insurance executives fell into this category. Only 2% of the fire fighters had blood pressure values greater than 160/90 mm Hg while 25% of the insurance executives were hypertensive. Thirty-two percent of the fire fighters were smokers at the time of testing as compared to 26% for the insurance executives. Only one fire fighter had all three risk factors elevated and only five had two risk factors elevated. Forty-seven of the fire fighters had no risk factors elevated. Ten percent of the fire fighters had ischemic stress tests as compared to 8% for the insurance executives. Of the nine fire fighters with ischemic stress tests one was hypertensive, one had elevated serum triglycerides, and three were smokers at the time of testing. Since the fire fighters are a medically-selected population with low risk factors for CHD, the observed incidence of ischemic stress tests is surprising and suggests that ischemic heart disease may be job associated.

Improving the sodium storage capacity of tunnel structured NaxFexTi2-xO4 (x = 1, 0.9 & 0.8) anode materials by tuning sodium deficiency

NASA Astrophysics Data System (ADS)

Bhange, Deu S.; Ali, Ghulam; Kim, Ji-Young; Chung, Kyung Yoon; Nam, Kyung-Wan

2017-10-01

Due to their abundance and environmentally benign nature, iron and titanium present as the most attractive potential elements for use in rechargeable sodium-ion batteries (SIBs). Accordingly, two structurally different Fe and Ti based compounds, stoichiometric NaFeTiO4 and sodium deficient NaxFexTi2-xO4 (where x = 0.9, and 0.8), are explored as anode materials for SIBs. Their structure and sodium storage capacity are systematically investigated by using combined structural and electrochemical analysis. Rietveld refinement analysis reveals that the sodium deficiency leads to the structural transformation from a single-tunnel structure (NaFeTiO4) to a zigzag-type double-tunnel structure (Na0.9Fe0.9Ti1.1O4 and Na0.8Fe0.8Ti1.2O4). The series of sodium deficient compounds bears systematic sodium ion vacancies in their structure up to 20%. Sodium deficiency in the NaxFexTi2-xO4 logically provides additional space for accommodating the excess sodium ions as such the NaxFexTi2-xO4 compounds with higher level of sodium deficiency show higher specific capacities than the stoichiometric NaFeTiO4. All the compounds exhibited very good electrochemical cycling stability, with minimal capacity loss during cycling. The present approach is a model example of improvement in the sodium storage capacity of the anode materials by tuning the chemical composition, and could facilitate the performance improvement of known or new electrode materials for SIBs.

Monitoring the Sodium Content of Restaurant Foods: Public Health Challenges and Opportunities

PubMed Central

Cogswell, Mary E.; Gunn, Janelle P.; Curtis, Christine J.; Rhodes, Donna; Hoy, Kathy; Pehrsson, Pamela; Nickle, Melissa; Merritt, Robert

2013-01-01

We reviewed methods of studies assessing restaurant foods’ sodium content and nutrition databases. We systematically searched the 1964–2012 literature and manually examined references in selected articles and studies. Twenty-six (5.2%) of the 499 articles we found met the inclusion criteria and were abstracted. Five were conducted nationally. Sodium content determination methods included laboratory analysis (n = 15), point-of-purchase nutrition information or restaurants’ Web sites (n = 8), and menu analysis with a nutrient database (n = 3). There is no comprehensive data system that provides all information needed to monitor changes in sodium or other nutrients among restaurant foods. Combining information from different sources and methods may help inform a comprehensive system to monitor sodium content reduction efforts in the US food supply and to develop future strategies. PMID:23865701

Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump

PubMed Central

Isaksen, Toke Jost; Vedovato, Natascia; Vitenzon, Ariel; Gadsby, David C.; Khodakhah, Kamran

2017-01-01

Mutations in the neuron-specific α3 isoform of the Na+/K+-ATPase are found in patients suffering from Rapid onset Dystonia Parkinsonism and Alternating Hemiplegia of Childhood, two closely related movement disorders. We show that mice harboring a heterozygous hot spot disease mutation, D801Y (α3+/D801Y), suffer abrupt hypothermia-induced dystonia identified by electromyographic recordings. Single-neuron in vivo recordings in awake α3+/D801Y mice revealed irregular firing of Purkinje cells and their synaptic targets, the deep cerebellar nuclei neurons, which was further exacerbated during dystonia and evolved into abnormal high-frequency burst-like firing. Biophysically, we show that the D-to-Y mutation abolished pump-mediated Na+/K+ exchange, but allowed the pumps to bind Na+ and become phosphorylated. These findings implicate aberrant cerebellar activity in α3 isoform-related dystonia and add to the functional understanding of the scarce and severe mutations in the α3 isoform Na+/K+-ATPase. PMID:28472154

Genetically increased cell-intrinsic excitability enhances neuronal integration into adult brain circuits

PubMed Central

Lin, Chia-Wei; Sim, Shuyin; Ainsworth, Alice; Okada, Masayoshi; Kelsch, Wolfgang; Lois, Carlos

2009-01-01

New neurons are added to the adult brain throughout life, but only half ultimately integrate into existing circuits. Sensory experience is an important regulator of the selection of new neurons but it remains unknown whether experience provides specific patterns of synaptic input, or simply a minimum level of overall membrane depolarization critical for integration. To investigate this issue, we genetically modified intrinsic electrical properties of adult-generated neurons in the mammalian olfactory bulb. First, we observed that suppressing levels of cell-intrinsic neuronal activity via expression of ESKir2.1 potassium channels decreases, whereas enhancing activity via expression of NaChBac sodium channels increases survival of new neurons. Neither of these modulations affects synaptic formation. Furthermore, even when neurons are induced to fire dramatically altered patterns of action potentials, increased levels of cell-intrinsic activity completely blocks cell death triggered by NMDA receptor deletion. These findings demonstrate that overall levels of cell-intrinsic activity govern survival of new neurons and precise firing patterns are not essential for neuronal integration into existing brain circuits. PMID:20152111

Motorcoach and school bus fire safety analysis.

DOT National Transportation Integrated Search

2016-11-01

This report documents a motorcoach and school bus fire safety analysis performed by the John A. Volpe National Transportation Systems Center (Volpe) for the Federal Motor Carrier Safety Administration. This report aims to: 1) identify the causes, fre...

Motorcoach and school bus fire safety analysis : technology brief.

DOT National Transportation Integrated Search

2016-11-01

In 2009, the Federal Motor Carrier Safety Administration (FMCSA) published findings from a study entitled Motorcoach Fire Safety Analysis. The objective of this study was to gather and analyze information regarding the causes, frequency, and se...

A new method for the analysis of fire spread modeling errors

Treesearch

Francis M. Fujioka

2002-01-01

Fire spread models have a long history, and their use will continue to grow as they evolve from a research tool to an operational tool. This paper describes a new method to analyse two-dimensional fire spread modeling errors, particularly to quantify the uncertainties of fire spread predictions. Measures of error are defined from the respective spread distances of...

Ring the Alarm! A Memo to the Schools on Fire and Human Beings.

ERIC Educational Resources Information Center

Educational Facilities Labs., Inc., New York, NY.

An analysis is presented of the handling of the human elements in fire safety. Emphasis is given to considerations such as how fires kill children, the school's responsibility for fire safety, causes of human failure, and the necessity for organized emergency programs and drills. Also included is a check list of items concerned with protection…

Airborne forest fire research

NASA Technical Reports Server (NTRS)

Mattingly, G. S.

1974-01-01

The research relating to airborne fire fighting systems is reviewed to provide NASA/Langley Research Center with current information on the use of aircraft in forest fire operations, and to identify research requirements for future operations. A literature survey, interview of forest fire service personnel, analysis and synthesis of data from research reports and independent conclusions, and recommendations for future NASA-LRC programs are included.

A biophysical model examining the role of low-voltage-activated potassium currents in shaping the responses of vestibular ganglion neurons.

PubMed

Hight, Ariel E; Kalluri, Radha

2016-08-01

The vestibular nerve is characterized by two broad groups of neurons that differ in the timing of their interspike intervals; some fire at highly regular intervals, whereas others fire at highly irregular intervals. Heterogeneity in ion channel properties has been proposed as shaping these firing patterns (Highstein SM, Politoff AL. Brain Res 150: 182-187, 1978; Smith CE, Goldberg JM. Biol Cybern 54: 41-51, 1986). Kalluri et al. (J Neurophysiol 104: 2034-2051, 2010) proposed that regularity is controlled by the density of low-voltage-activated potassium currents (IKL). To examine the impact of IKL on spike timing regularity, we implemented a single-compartment model with three conductances known to be present in the vestibular ganglion: transient sodium (gNa), low-voltage-activated potassium (gKL), and high-voltage-activated potassium (gKH). Consistent with in vitro observations, removing gKL depolarized resting potential, increased input resistance and membrane time constant, and converted current step-evoked firing patterns from transient (1 spike at current onset) to sustained (many spikes). Modeled neurons were driven with a time-varying synaptic conductance that captured the random arrival times and amplitudes of glutamate-driven synaptic events. In the presence of gKL, spiking occurred only in response to large events with fast onsets. Models without gKL exhibited greater integration by responding to the superposition of rapidly arriving events. Three synaptic conductance were modeled, each with different kinetics to represent a variety of different synaptic processes. In response to all three types of synaptic conductance, models containing gKL produced spike trains with irregular interspike intervals. Only models lacking gKL when driven by rapidly arriving small excitatory postsynaptic currents were capable of generating regular spiking. Copyright © 2016 the American Physiological Society.

The Influence of Rainfall, Vegetation, Elephants and People on Fire Frequency of Miombo Woodlands, Northern Mozambique

NASA Astrophysics Data System (ADS)

Ribeiro, N. S.; Okin, G. S.; Shugart, H. H.; Swap, R. J.

2008-12-01

Miombo woodlands are important in southern Africa as they occupy over 50% of the land and, their good and services support a large proportion of people in the region. Anthropogenic fires occur in miombo every year especially in the dry season (May - October). This study explores the influence of annual rainfall, elephant density, human density and corridors, and vegetation on the fire frequency. It was carried out in Niassa Reserve located in northern Mozambique, the largest and more pristine conservation area of miombo woodlands in the world. We used a time series analysis and statistical t-test of MODIS-derived Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI) to explore the relationship between biomass and fire frequency. The influence of rainfall, elephants, people and vegetation on fire return was explored using a stepwise logistic regression analysis. The results of this study indicate that fire frequency is higher in places with high biomass at beginning of the dry season. In these areas fire seems to be more intense and to strongly reduce biomass in the late dry season. Land cover is the strongest predictor of fire frequency, but elephant density, annual rainfall and human corridors are also important.

The influence of rainfall, vegetation, elephants and people on fire frequency of miombo woodlands, northern Mozambique

NASA Astrophysics Data System (ADS)

Ribeiro, N. S.; Okin, G. S.; Shugart, H.; Swap, R.

2007-12-01

Miombo woodlands are important in southern Africa as they occupy over 50% of the land and, their good and services support a large proportion of people in the region. Anthropogenic fires occur in miombo every year especially in the dry season (May - October). This study explores the influence of annual rainfall, elephant density, human density and corridors, and vegetation on the fire frequency. It was carried out in Niassa Reserve located in northern Mozambique, the largest and more pristine conservation area of miombo woodlands in the world. We used a time series analysis and statistical t-test of MODIS-derived Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI) to explore the relationship between biomass and fire frequency. The influence of rainfall, elephants, people and vegetation on fire return was explored using a stepwise logistic regression analysis. The results of this study indicate that fire frequency is higher in places with high biomass at beginning of the dry season. In these areas fire seems to be more intense and to strongly reduce biomass in the late dry season. Land cover is the strongest predictor of fire frequency, but elephant density, annual rainfall and human corridors are also important.

Microbiological corrosion of ASTM SA105 carbon steel pipe for industrial fire water usage

NASA Astrophysics Data System (ADS)

Chidambaram, S.; Ashok, K.; Karthik, V.; Venkatakrishnan, P. G.

2018-02-01

The large number of metallic systems developed for last few decades against both general uniform corrosion and localized corrosion. Among all microbiological induced corrosion (MIC) is attractive, multidisciplinary and complex in nature. Many chemical processing industries utilizes fresh water for fire service to nullify major/minor fire. One such fire water service line pipe attacked by micro-organisms leads to leakage which is industrially important from safety point of view. Also large numbers of leakage reported in similar fire water service of nearby food processing plant, paper & pulp plant, steel plant, electricity board etc…In present investigation one such industrial fire water service line failure analysis of carbon steel line pipe was analyzed to determine the cause of failure. The water sample subjected to various chemical and bacterial analyses. Turbidity, pH, calcium hardness, free chlorine, oxidation reduction potential, fungi, yeasts, sulphide reducing bacteria (SRB) and total bacteria (TB) were measured on water sample analysis. The corrosion rate was measured on steel samples and corrosion coupon measurements were installed in fire water for validating non flow assisted localized corrosion. The sulphide reducing bacteria (SRB) presents in fire water causes a localized micro biological corrosion attack of line pipe.

Wildland fire management. Volume 1: Prevention methods and analysis. [systems engineering approach to California fire problems

NASA Technical Reports Server (NTRS)

Weissenberger, S. (Editor)

1973-01-01

A systems engineering approach is reported for the problem of reducing the number and severity of California's wildlife fires. Prevention methodologies are reviewed and cost benefit models are developed for making preignition decisions.

Fire Safety of Passenger Trains : Phase II : Application of Fire Hazard Analysis Techniques

DOT National Transportation Integrated Search

2001-12-01

On May 12, 1999, the Federal Railroad Administration (FRA) issued regulations for passenger rail equipment safety standards that included small-scale fire tests and performance criteria to evaluate the flammability and smoke characteristics of indivi...

Fire safety of passenger trains. Phase II, Application of fire hazard analysis techniques.

DOT National Transportation Integrated Search

2001-12-01

On May 12, 1999, the Federal Railroad Administration (FRA) issued regulations for passenger rail equipment safety standards that included small-scale fire tests and performance criteria to evaluate the flammability and smoke characteristics of indivi...

Climate drives inter-annual variability in probability of high severity fire occurrence in the western United States

NASA Astrophysics Data System (ADS)

Keyser, Alisa; Westerling, Anthony LeRoy

2017-05-01

A long history of fire suppression in the western United States has significantly changed forest structure and ecological function, leading to increasingly uncharacteristic fires in terms of size and severity. Prior analyses of fire severity in California forests showed that time since last fire and fire weather conditions predicted fire severity very well, while a larger regional analysis showed that topography and climate were important predictors of high severity fire. There has not yet been a large-scale study that incorporates topography, vegetation and fire-year climate to determine regional scale high severity fire occurrence. We developed models to predict the probability of high severity fire occurrence for the western US. We predict high severity fire occurrence with some accuracy, and identify the relative importance of predictor classes in determining the probability of high severity fire. The inclusion of both vegetation and fire-year climate predictors was critical for model skill in identifying fires with high fractional fire severity. The inclusion of fire-year climate variables allows this model to forecast inter-annual variability in areas at future risk of high severity fire, beyond what slower-changing fuel conditions alone can accomplish. This allows for more targeted land management, including resource allocation for fuels reduction treatments to decrease the risk of high severity fire.

Fire-induced albedo change and surface radiative forcing in sub-Saharan Africa savanna ecosystems: Implications for the energy balance

NASA Astrophysics Data System (ADS)

Dintwe, Kebonye; Okin, Gregory S.; Xue, Yongkang

2017-06-01

Surface albedo is a critical parameter that controls surface energy balance. In dryland ecosystems, fires play a significant role in decreasing surface albedo, resulting in positive radiative forcing. Here we investigate the long-term effect of fire on surface albedo. We devised a method to calculate short-, medium-, and long-term effect of fire-induced radiative forcing and their relative effects on energy balance. We used Moderate Resolution Imaging Spectroradiometer (MODIS) data in our analysis, covering different vegetation classes in sub-Saharan Africa (SSA). Our analysis indicated that mean short-term fire-induced albedo change in SSA was -0.022, -0.035, and -0.041 for savannas, shrubland, and grasslands, respectively. At regional scale, mean fire-induced albedo change in savannas was -0.018 and -0.024 for northern sub-Saharan of Africa and the southern hemisphere Africa, respectively. The short-term mean fire-induced radiative forcing in burned areas in sub-Saharan Africa (SSA) was 5.41 W m-2, which contributed continental and global radiative forcings of 0.25 and 0.058 W m-2, respectively. The impact of fire in surface albedo has long-lasting effects that varies with vegetation type. The long-term energetic effects of fire-induced albedo change and associated radiative forcing were, on average, more than 19 times greater across SSA than the short-term effects, suggesting that fires exerted far more radiative forcing than previously thought. Taking into account the actual duration of fire's effect on surface albedo, we conclude that the contribution of SSA fires, globally and throughout the year, is 0.12 W m-2. These findings provide crucial information on possible impact of fire on regional climate variability.

Gis-Based Multi-Criteria Decision Analysis for Forest Fire Risk Mapping

NASA Astrophysics Data System (ADS)

Akay, A. E.; Erdoğan, A.

2017-11-01

The forested areas along the coastal zone of the Mediterranean region in Turkey are classified as first-degree fire sensitive areas. Forest fires are major environmental disaster that affects the sustainability of forest ecosystems. Besides, forest fires result in important economic losses and even threaten human lives. Thus, it is critical to determine the forested areas with fire risks and thereby minimize the damages on forest resources by taking necessary precaution measures in these areas. The risk of forest fire can be assessed based on various factors such as forest vegetation structures (tree species, crown closure, tree stage), topographic features (slope and aspect), and climatic parameters (temperature, wind). In this study, GIS-based Multi-Criteria Decision Analysis (MCDA) method was used to generate forest fire risk map. The study was implemented in the forested areas within Yayla Forest Enterprise Chiefs at Dursunbey Forest Enterprise Directorate which is classified as first degree fire sensitive area. In the solution process, "extAhp 2.0" plug-in running Analytic Hierarchy Process (AHP) method in ArcGIS 10.4.1 was used to categorize study area under five fire risk classes: extreme risk, high risk, moderate risk, and low risk. The results indicated that 23.81 % of the area was of extreme risk, while 25.81 % was of high risk. The result indicated that the most effective criterion was tree species, followed by tree stages. The aspect had the least effective criterion on forest fire risk. It was revealed that GIS techniques integrated with MCDA methods are effective tools to quickly estimate forest fire risk at low cost. The integration of these factors into GIS can be very useful to determine forested areas with high fire risk and also to plan forestry management after fire.

Erosion Risks in Selected Watersheds for the 2005 School Fire Located Near Pomeroy, Washington on Predominately Ash-Cap Soils

Treesearch

William Elliot; Ina Sue Miller; Brandon Glaza

2007-01-01

A limited erosion potential analysis was carried out on the 50,000 acre School Fire. Three WEPP interfaces were used for the analysis, a GIS wizard, an online interface and a windows interface. Ten watersheds within the fire area were modeled with the GeoWEPP tool (a geo-spatial interface for WEPP, Water Erosion Predication Project). The watersheds covered 18,823 acres...

75 FR 5633 - Notice of Extension of Comment Period for NUREG-1921, EPRI/NRC-RES Fire Human Reliability...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-03

..., EPRI/NRC- RES Fire Human Reliability Analysis Guidelines, Draft Report for Comment AGENCY: Nuclear... Human Reliability Analysis Guidelines, Draft Report for Comment'' (December 11, 2009; 74 FR 65810). This... Human Reliability Analysis Guidelines'' is available electronically under ADAMS Accession Number...

[Study on discrimination of varieties of fire resistive coating for steel structure based on near-infrared spectroscopy].

PubMed

Xue, Gang; Song, Wen-qi; Li, Shu-chao

2015-01-01

In order to achieve the rapid identification of fire resistive coating for steel structure of different brands in circulating, a new method for the fast discrimination of varieties of fire resistive coating for steel structure by means of near infrared spectroscopy was proposed. The raster scanning near infrared spectroscopy instrument and near infrared diffuse reflectance spectroscopy were applied to collect the spectral curve of different brands of fire resistive coating for steel structure and the spectral data were preprocessed with standard normal variate transformation(standard normal variate transformation, SNV) and Norris second derivative. The principal component analysis (principal component analysis, PCA)was used to near infrared spectra for cluster analysis. The analysis results showed that the cumulate reliabilities of PC1 to PC5 were 99. 791%. The 3-dimentional plot was drawn with the scores of PC1, PC2 and PC3 X 10, which appeared to provide the best clustering of the varieties of fire resistive coating for steel structure. A total of 150 fire resistive coating samples were divided into calibration set and validation set randomly, the calibration set had 125 samples with 25 samples of each variety, and the validation set had 25 samples with 5 samples of each variety. According to the principal component scores of unknown samples, Mahalanobis distance values between each variety and unknown samples were calculated to realize the discrimination of different varieties. The qualitative analysis model for external verification of unknown samples is a 10% recognition ration. The results demonstrated that this identification method can be used as a rapid, accurate method to identify the classification of fire resistive coating for steel structure and provide technical reference for market regulation.

Meteosat SEVIRI Fire Radiative Power (FRP) products from the Land Surface Analysis Satellite Applications Facility (LSA SAF) - Part 1: Algorithms, product contents and analysis

NASA Astrophysics Data System (ADS)

Wooster, M. J.; Roberts, G.; Freeborn, P. H.; Xu, W.; Govaerts, Y.; Beeby, R.; He, J.; Lattanzio, A.; Mullen, R.

2015-06-01

Characterising changes in landscape scale fire activity at very high temporal resolution is best achieved using thermal observations of actively burning fires made from geostationary Earth observation (EO) satellites. Over the last decade or more, a series of research and/or operational "active fire" products have been developed from these types of geostationary observations, often with the aim of supporting the generation of data related to biomass burning fuel consumption and trace gas and aerosol emission fields. The Fire Radiative Power (FRP) products generated by the Land Surface Analysis Satellite Applications Facility (LSA SAF) from data collected by the Meteosat Second Generation (MSG) Spinning Enhanced Visible and Infrared Imager (SEVIRI) are one such set of products, and are freely available in both near real-time and archived form. Every 15 min, the algorithms used to generate these products identify and map the location of new SEVIRI observations containing actively burning fires, and characterise their individual rates of radiative energy release (fire radiative power; FRP) that is believed proportional to rates of biomass consumption and smoke emission. The FRP-PIXEL product contains the highest spatial resolution FRP dataset, delivered for all of Europe, northern and southern Africa, and part of South America at a spatial resolution of 3 km (decreasing away from the west African sub-satellite point) at the full 15 min temporal resolution. The FRP-GRID product is an hourly summary of the FRP-PIXEL data, produced at a 5° grid cell size and including simple bias adjustments for meteorological cloud cover and for the regional underestimation of FRP caused, primarily, by the non-detection of low FRP fire pixels at SEVIRI's relatively coarse pixel size. Here we describe the enhanced geostationary Fire Thermal Anomaly (FTA) algorithm used to detect the SEVIRI active fire pixels, and detail methods used to deliver atmospherically corrected FRP information together with the per-pixel uncertainty metrics. Using scene simulations and analysis of real SEVIRI data, including from a period of Meteosat-8 "special operations", we describe some of the sensor and data pre-processing characteristics influencing fire detection and FRP uncertainty. We show that the FTA algorithm is able to discriminate actively burning fires covering down to 10-4 of a pixel, and is more sensitive to fire than algorithms used within many other widely exploited active fire products. We also find that artefacts arising from the digital filtering and geometric resampling strategies used to generate level 1.5 SEVIRI data can significantly increase FRP uncertainties in the SEVIRI active fire products, and recommend that the processing chains used for the forthcoming Meteosat Third Generation attempt to minimise the impact of these types of operations. Finally, we illustrate the information contained within the current Meteosat FRP-PIXEL and FRP-GRID products, providing example analyses for both individual fires and multi-year regional-scale fire activity. A companion paper (Roberts et al., 2015) provides a full product performance evaluation for both products, along with examples of their use for prescribing fire smoke emissions within atmospheric modelling components of the Copernicus Atmosphere Monitoring Service (CAMS).

Satellite Analysis of the Severe 1987 Forest Fires in Northern China and Southeastern Siberia

NASA Technical Reports Server (NTRS)

Cahoon, Donald R., Jr.; Stocks, Brian J.; Levine, Joel S.; Cofer, Wesley R., III; Pierson, Joseph M.

1994-01-01

Meteorological conditions, extremely conducive to fire development and spread in the spring of 1987, resulted in forest fires burning over extremely large areas in the boreal forest zone in northeastern China and the southeastern region of Siberia. The great China fire, one of the largest and most destructive forest fires in recent history, occurred during this period in the Heilongjiang Province of China. Satellite imagery is used to examine the development and areal distribution of 1987 forest fires in this region. Overall trace gas emissions to the atmosphere from these fires are determined using a satellite-derived estimate of area burned in combination with fuel consumption figures and carbon emission ratios for boreal forest fires.

Satellite analysis of the severe 1987 forest fires in northern China and southeastern Siberia

NASA Technical Reports Server (NTRS)

Cahoon, Donald R, Jr.; Stocks, Brian J.; Levine, Joel S.; Cofer, Wesley R., III; Pierson, Joseph M.

1994-01-01

Meteorological conditions, extremely conducive to fire development and spread in the spring of 1987, resulted in forest fires burning over extremely large areas in the boreal forest zone in northeastern China and the southeastern region of Siberia. The great China fire, one of the largest and most destructive forest fires in recent history, occurred during this period in the Heilongjiang Province of China. Satellite imagery is used to examine the development and areal distribution of 1987 forest fires in this region. Overall trace gas emissions to the atmosphere from these fires are determined using a satellite-derived estimate of area burned in combination with fuel consumption figures and carbon emission ratios for boreal forest fires.

Precipitation composition and wet deposition temporal pattern in Central Serbia for the period from 1998 to 2004.

PubMed

Golobocanin, D; Zujić, A; Milenković, A; Miljević, N

2008-07-01

Bulk samples collected on a daily basis at three principal meteorological stations in central Serbia were analyzed on chloride (Cl(-)), nitrate (NO(3)(-)), sulfate (SO(4)(2-)), sodium (Na(+)), ammonium (NH(4)(+)), potassium (K(+)), calcium (Ca(2+)), and magnesium (Mg(2+)) in addition to precipitation amount, pH and conductivity measurements over the period 1998-2004. The data were subjected to variety of analyses (linear regression, principal component analysis, time series analysis) to characterize precipitation chemistry in the study area. The most abundant ion was SO(2-)(4) with annual volume weighted mean concentration of 242 microeq L(-1). Neutralization of precipitation acidity occurs both as a result of the dissolution of alkaline compounds containing Ca(2+), Mg(2+), and K(+) as well as the absorption of ammonia. The ratio of SO(4)(2-)/NO(3)(-) was above 5, which indicated that the combustion process of low-grade domestic lignite for electricity generation from coal-fired thermal power plants was the main source of pollution in the investigated area. A considerable mean annual bulk wet deposition of SO(4)-S determined by precipitation amount and concentrations of sulfate in the precipitation was calculated to be 12-35 kg ha(-1).

Long-Range Temporal Correlations, Multifractality, and the Causal Relation between Neural Inputs and Movements

PubMed Central

Hu, Jing; Zheng, Yi; Gao, Jianbo

2013-01-01

Understanding the causal relation between neural inputs and movements is very important for the success of brain-machine interfaces (BMIs). In this study, we analyze 104 neurons’ firings using statistical, information theoretic, and fractal analysis. The latter include Fano factor analysis, multifractal adaptive fractal analysis (MF-AFA), and wavelet multifractal analysis. We find neuronal firings are highly non-stationary, and Fano factor analysis always indicates long-range correlations in neuronal firings, irrespective of whether those firings are correlated with movement trajectory or not, and thus does not reveal any actual correlations between neural inputs and movements. On the other hand, MF-AFA and wavelet multifractal analysis clearly indicate that when neuronal firings are not well correlated with movement trajectory, they do not have or only have weak temporal correlations. When neuronal firings are well correlated with movements, they are characterized by very strong temporal correlations, up to a time scale comparable to the average time between two successive reaching tasks. This suggests that neurons well correlated with hand trajectory experienced a “re-setting” effect at the start of each reaching task, in the sense that within the movement correlated neurons the spike trains’ long-range dependences persisted about the length of time the monkey used to switch between task executions. A new task execution re-sets their activity, making them only weakly correlated with their prior activities on longer time scales. We further discuss the significance of the coalition of those important neurons in executing cortical control of prostheses. PMID:24130549

Exploratory spatial data analysis of global MODIS active fire data

NASA Astrophysics Data System (ADS)

Oom, D.; Pereira, J. M. C.

2013-04-01

We performed an exploratory spatial data analysis (ESDA) of autocorrelation patterns in the NASA MODIS MCD14ML Collection 5 active fire dataset, for the period 2001-2009, at the global scale. The dataset was screened, resulting in an annual rate of false alarms and non-vegetation fires ranging from a minimum of 3.1% in 2003 to a maximum of 4.4% in 2001. Hot bare soils and gas flares were the major sources of false alarms and non-vegetation fires. The data were aggregated at 0.5° resolution for the global and local spatial autocorrelation Fire counts were found to be positively correlated up to distances of around 200 km, and negatively for larger distances. A value of 0.80 (p = 0.001, α = 0.05) for Moran's I indicates strong spatial autocorrelation between fires at global scale, with 60% of all cells displaying significant positive or negative spatial correlation. Different types of spatial autocorrelation were mapped and regression diagnostics allowed for the identification of spatial outlier cells, with fire counts much higher or lower than expected, considering their spatial context.

Release of volatile and semi-volatile toxicants during house fires.

PubMed

Hewitt, Fiona; Christou, Antonis; Dickens, Kathryn; Walker, Richard; Stec, Anna A

2017-04-01

Qualitative results are presented from analysis of volatile and semi-volatile organic compounds (VOCs/SVOCs) obtained through sampling of gaseous effluent and condensed particulates during a series of experimental house fires conducted in a real house. Particular emphasis is given to the 16 polycyclic aromatic hydrocarbons (PAHs) listed by the Environmental Protection Agency due to their potentially carcinogenic effects. The initial fuel packages were either cooking oil or a single sofa; these were burned both alone, and in furnished surroundings. Experiments were performed at different ventilation conditions. Qualitative Gas Chromatography-Mass Spectrometry (GC-MS) analysis found VOC/SVOC releases in the developing stages of the fires, and benzo(a)pyrene - the most carcinogenic PAH - was found in at least one sampling interval in the majority of fires. A number of phosphorus fire retardants were detected, in both the gaseous effluent and particulates, from fires where the initial fuel source was a sofa. Their release during the fire is significant as they pose toxicological concerns separate from those presented by the PAHs. Copyright © 2016. Published by Elsevier Ltd.

Bispectral infrared forest fire detection and analysis using classification techniques

NASA Astrophysics Data System (ADS)

Aranda, Jose M.; Melendez, Juan; de Castro, Antonio J.; Lopez, Fernando

2004-01-01

Infrared cameras are well established as a useful tool for fire detection, but their use for quantitative forest fire measurements faces difficulties, due to the complex spatial and spectral structure of fires. In this work it is shown that some of these difficulties can be overcome by applying classification techniques, a standard tool for the analysis of satellite multispectral images, to bi-spectral images of fires. Images were acquired by two cameras that operate in the medium infrared (MIR) and thermal infrared (TIR) bands. They provide simultaneous and co-registered images, calibrated in brightness temperatures. The MIR-TIR scatterplot of these images can be used to classify the scene into different fire regions (background, ashes, and several ember and flame regions). It is shown that classification makes possible to obtain quantitative measurements of physical fire parameters like rate of spread, embers temperature, and radiated power in the MIR and TIR bands. An estimation of total radiated power and heat release per unit area is also made and compared with values derived from heat of combustion and fuel consumption.

Thermodynamic analysis of a new conception of supplementary firing in a combined cycle

NASA Astrophysics Data System (ADS)

Kotowicz, Janusz; Bartela, Łukasz; Balicki, Adrian

2010-10-01

The paper analyzes a new concept of integration of combined cycle with the installation of supplementary firing. The whole system was enclosed by thermodynamic analysis, which consists of a gas-steam unit with triple-pressure heat recovery steam generator. The system uses a determined model of the gas turbine and the assumptions relating to the construction features of steam-water part were made. The proposed conception involves building of supplementary firing installation only on part of the exhaust stream leaving the gas turbine. In the proposed solution superheater was divided into two sections, one of which was located on the exhaust gases leaving the installation of supplementary firing. The paper presents the results of the analyses of which the main aim was to demonstrate the superiority of the new thermodynamic concept of the supplementary firing over the classical one. For this purpose a model of a system was built, in which it was possible to carry out simulations of the gradual transition from a classically understood supplementary firing to the supplementary firing completely modified. For building of a model the GateCycle™ software was used.

Investment appraisal using quantitative risk analysis.

PubMed

Johansson, Henrik

2002-07-01

Investment appraisal concerned with investments in fire safety systems is discussed. Particular attention is directed at evaluating, in terms of the Bayesian decision theory, the risk reduction that investment in a fire safety system involves. It is shown how the monetary value of the change from a building design without any specific fire protection system to one including such a system can be estimated by use of quantitative risk analysis, the results of which are expressed in terms of a Risk-adjusted net present value. This represents the intrinsic monetary value of investing in the fire safety system. The method suggested is exemplified by a case study performed in an Avesta Sheffield factory.

Dimensional Analysis on Forest Fuel Bed Fire Spread.

PubMed

Yang, Jiann C

2018-01-01

A dimensional analysis was performed to correlate the fuel bed fire rate of spread data previously reported in the literature. Under wind condition, six pertinent dimensionless groups were identified, namely dimensionless fire spread rate, dimensionless fuel particle size, fuel moisture content, dimensionless fuel bed depth or dimensionless fuel loading density, dimensionless wind speed, and angle of inclination of fuel bed. Under no-wind condition, five similar dimensionless groups resulted. Given the uncertainties associated with some of the parameters used to estimate the dimensionless groups, the dimensionless correlations using the resulting dimensionless groups correlate the fire rates of spread reasonably well under wind and no-wind conditions.

Crisis management with applicability on fire fighting plants

NASA Astrophysics Data System (ADS)

Panaitescu, M.; Panaitescu, F. V.; Voicu, I.; Dumitrescu, L. G.

2017-08-01

The paper presents a case study for a crisis management analysis which address to fire fighting plants. The procedures include the steps of FTA (Failure tree analysis). The purpose of the present paper is to describe this crisis management plan with tools of FTA. The crisis management procedures have applicability on anticipated and emergency situations and help to describe and planning a worst-case scenario plan. For this issue must calculate the probabilities in different situations for fire fighting plants. In the conclusions of paper is analised the block diagram with components of fire fighting plant and are presented the solutions for each possible risk situations.

Risk management of key issues of FPSO

NASA Astrophysics Data System (ADS)

Sun, Liping; Sun, Hai

2012-12-01

Risk analysis of key systems have become a growing topic late of because of the development of offshore structures. Equipment failures of offloading system and fire accidents were analyzed based on the floating production, storage and offloading (FPSO) features. Fault tree analysis (FTA), and failure modes and effects analysis (FMEA) methods were examined based on information already researched on modules of relex reliability studio (RRS). Equipment failures were also analyzed qualitatively by establishing a fault tree and Boolean structure function based on the shortage of failure cases, statistical data, and risk control measures examined. Failure modes of fire accident were classified according to the different areas of fire occurrences during the FMEA process, using risk priority number (RPN) methods to evaluate their severity rank. The qualitative analysis of FTA gave the basic insight of forming the failure modes of FPSO offloading, and the fire FMEA gave the priorities and suggested processes. The research has practical importance for the security analysis problems of FPSO.

The 1977 tundra fire at Kokolik River, Alaska

NASA Technical Reports Server (NTRS)

Hall, D.; Brown, J.; Johnson, L.

1981-01-01

During the summer of 1977, fire totaled 44 sq km of tundra vegetation according to measurements using LANDSAT imagery. Based on the experience gained from analysis of this fire using ground observations, satellite imagery, and topographic maps, it appears that natural drainages form effective fire breaks on the subdued relief of the Arctic coastal plain and northern foothills. It is confirmed that the intensity of the fire is related to vegetation type and to the moisture content of the organic rich soils.

Focused sunlight factor of forest fire danger assessment using Web-GIS and RS technologies

NASA Astrophysics Data System (ADS)

Baranovskiy, Nikolay V.; Sherstnyov, Vladislav S.; Yankovich, Elena P.; Engel, Marina V.; Belov, Vladimir V.

2016-08-01

Timiryazevskiy forestry of Tomsk region (Siberia, Russia) is a study area elaborated in current research. Forest fire danger assessment is based on unique technology using probabilistic criterion, statistical data on forest fires, meteorological conditions, forest sites classification and remote sensing data. MODIS products are used for estimating some meteorological conditions and current forest fire situation. Geonformation technologies are used for geospatial analysis of forest fire danger situation on controlled forested territories. GIS-engine provides opportunities to construct electronic maps with different levels of forest fire probability and support raster layer for satellite remote sensing data on current forest fires. Web-interface is used for data loading on specific web-site and for forest fire danger data representation via World Wide Web. Special web-forms provide interface for choosing of relevant input data in order to process the forest fire danger data and assess the forest fire probability.

Single Crystal Membranes

NASA Technical Reports Server (NTRS)

Stormont, R. W.; Morrison, A.

1974-01-01

Single crystal a- and c-axis tubes and ribbons of sodium beta-alumina and sodium magnesium beta-alumina were grown from sodium oxide rich melts. Additional experiments grew ribbon crystals containing sodium magnesium beta, beta double prime, beta triple prime, and beta quadruple prime. A high pressure crystal growth chamber, sodium oxide rich melts, and iridium for all surfaces in contact with the melt were combined with the edge-defined, film-fed growth technique to grow the single crystal beta-alumina tubes and ribbons. The crystals were characterized using metallographic and X-ray diffraction techniques, and wet chemical analysis was used to determine the sodium, magnesium, and aluminum content of the grown crystals.

Oxygen-Sodium Anticorrelation in Field RR Lyr-Type Stars

NASA Astrophysics Data System (ADS)

Andrievsky, S.; Korotin, S.; Lyashko, D.; Tsymbal, V.

2017-06-01

We have performed analysis of a large amount of the fields RR Lyr type stars spectra with the aim to derive NLTE oxygen and sodium abundances in our program stars. Fundamental parameters (Teff, log g, Vt) and metallicity were found using the method of the fitting between synthetic and observed spectra using the SME program which was developed by N. Piskunov and J. A. Valenti. As a result of this analysis anticorrelation between oxygen (O/H) and sodium (Na/H) abundances was found.

Multivariate statistical analysis of wildfires in Portugal

NASA Astrophysics Data System (ADS)

Costa, Ricardo; Caramelo, Liliana; Pereira, Mário

2013-04-01

Several studies demonstrate that wildfires in Portugal present high temporal and spatial variability as well as cluster behavior (Pereira et al., 2005, 2011). This study aims to contribute to the characterization of the fire regime in Portugal with the multivariate statistical analysis of the time series of number of fires and area burned in Portugal during the 1980 - 2009 period. The data used in the analysis is an extended version of the Rural Fire Portuguese Database (PRFD) (Pereira et al, 2011), provided by the National Forest Authority (Autoridade Florestal Nacional, AFN), the Portuguese Forest Service, which includes information for more than 500,000 fire records. There are many multiple advanced techniques for examining the relationships among multiple time series at the same time (e.g., canonical correlation analysis, principal components analysis, factor analysis, path analysis, multiple analyses of variance, clustering systems). This study compares and discusses the results obtained with these different techniques. Pereira, M.G., Trigo, R.M., DaCamara, C.C., Pereira, J.M.C., Leite, S.M., 2005: "Synoptic patterns associated with large summer forest fires in Portugal". Agricultural and Forest Meteorology. 129, 11-25. Pereira, M. G., Malamud, B. D., Trigo, R. M., and Alves, P. I.: The history and characteristics of the 1980-2005 Portuguese rural fire database, Nat. Hazards Earth Syst. Sci., 11, 3343-3358, doi:10.5194/nhess-11-3343-2011, 2011 This work is supported by European Union Funds (FEDER/COMPETE - Operational Competitiveness Programme) and by national funds (FCT - Portuguese Foundation for Science and Technology) under the project FCOMP-01-0124-FEDER-022692, the project FLAIR (PTDC/AAC-AMB/104702/2008) and the EU 7th Framework Program through FUME (contract number 243888).

Fire behavior and risk analysis in spacecraft

NASA Technical Reports Server (NTRS)

Friedman, Robert; Sacksteder, Kurt R.

1988-01-01

Practical risk management for present and future spacecraft, including space stations, involves the optimization of residual risks balanced by the spacecraft operational, technological, and economic limitations. Spacecraft fire safety is approached through three strategies, in order of risk: (1) control of fire-causing elements, through exclusion of flammable materials for example; (2) response to incipient fires through detection and alarm; and (3) recovery of normal conditions through extinguishment and cleanup. Present understanding of combustion in low gravity is that, compared to normal gravity behavior, fire hazards may be reduced by the absence of buoyant gas flows yet at the same time increased by ventilation flows and hot particle expulsion. This paper discusses the application of low-gravity combustion knowledge and appropriate aircraft analogies to fire detection, fire fighting, and fire-safety decisions for eventual fire-risk management and optimization in spacecraft.

Multi-season climate synchronized historical fires in dry forests (1650-1900), Northern Rockies, USA

Treesearch

Emily K. Heyerdahl; Penelope Morgan; James P. Riser

2008-01-01

Our objective was to infer the climate drivers of regionally synchronous fire years in dry forests of the U.S. northern Rockies in Idaho and western Montana. During our analysis period (1650-­1900), we reconstructed fires from 9245 fire scars on 576 trees (mostly ponderosa pine, Pinus ponderosa P. & C. Lawson) at 21 sites and compared them to...

Fire as a galvanizing and fragmenting influence on communities: the case of the Rodeo-Chediski fire

Treesearch

Matthew S. Carroll; Patricia J. Cohn; David N. Seesholtz; Lorie L. Higgins

2005-01-01

Large wildfires that burn through the "forest-residential intermix" are complex events with a variety of social impacts. This study looks at three northern Arizona community clusters directly affected by the 2002 Rodeo-Chediski fire. Our analysis suggests that the fire event led to both the emergence of cohesion and conflict in the study area. Community...

Simulated western spruce budworm defoliation reduces torching and crowning potential: A sensitivity analysis using a physics-based fire model

Treesearch

Gregory M. Cohn; Russell A. Parsons; Emily K. Heyerdahl; Daniel G. Gavin; Aquila Flower

2014-01-01

The widespread, native defoliator western spruce budworm (Choristoneura occidentalis Freeman) reduces canopy fuels, which might affect the potential for surface fires to torch (ignite the crowns of individual trees) or crown (spread between tree crowns). However, the effects of defoliation on fire behaviour are poorly understood. We used a physics-based fire model to...

Integrating fire behavior models and geospatial analysis for wildland fire risk assessment and fuel management planning

Treesearch

Alan A. Ager; Nicole M. Vaillant; Mark A. Finney

2011-01-01

Wildland fire risk assessment and fuel management planning on federal lands in the US are complex problems that require state-of-the-art fire behavior modeling and intensive geospatial analyses. Fuel management is a particularly complicated process where the benefits and potential impacts of fuel treatments must be demonstrated in the context of land management goals...

Effectiveness of sodium azide alone compared to sodium azide in combination with methyl nitrosurea for rice mutagenesis

USDA-ARS?s Scientific Manuscript database

Rice seeds of the temperate japonica cultivar Kitaake were mutagenized with sodium azide alone and in combination with methyl nitrosourea. Using the reduced representation sequencing method Restriction Enzyme Sequence Comparative Analysis (RESCAN), the mutation densities, types and local sequence co...

Nonfatal residential fire-related injuries treated in emergency departments--United States, 2001.

PubMed

2003-09-26

During 2000, the most recent year for which national mortality data are available, 3,907 persons died in the United States from fire-related injuries; residential fires accounted for 2,955 (76%) of these deaths. The National Fire Protection Association (NFPA) reported that approximately 396,500 residential fires occurred in 2001. Injuries from residential fires are preventable by improving awareness of the common causes of fires and by using simple interventions (e.g., properly maintained smoke alarms and fire escape plans). Surveillance of fire-related injuries can aid prevention by increasing the understanding of these injuries and by identifying at-risk populations to target for interventions and education. To characterize nonfatal residential fire-related injuries treated in U.S. hospital emergency departments (EDs) during 2001, CDC analyzed data from the National Electronic Injury Surveillance System-All Injury Program (NEISS-AIP). This report summarizes the results of that analysis, which indicate that, in 2001, an estimated 25,717 nonfatal residential fire-related injuries were treated in U.S. hospital EDs. Fire prevention and safety interventions and education should target at-risk populations for fire-related injuries.

Fire regime in Mediterranean ecosystem

NASA Astrophysics Data System (ADS)

Biondi, Guido; Casula, Paolo; D'Andrea, Mirko; Fiorucci, Paolo

2010-05-01

The analysis of burnt areas time series in Mediterranean regions suggests that ecosystems characterising this area consist primarily of species highly vulnerable to the fire but highly resilient, as characterized by a significant regenerative capacity after the fire spreading. In a few years the area burnt may once again be covered by the same vegetation present before the fire. Similarly, Mediterranean conifer forests, which often refers to plantations made in order to reforest the areas most severely degraded with high erosion risk, regenerate from seed after the fire resulting in high resilience to the fire as well. Only rarely, and usually with negligible damages, fire affects the areas covered by climax species in relation with altitude and soil types (i.e, quercus, fagus, abies). On the basis of these results, this paper shows how the simple Drossel-Schwabl forest fire model is able to reproduce the forest fire regime in terms of number of fires and burned area, describing whit good accuracy the actual fire perimeters. The original Drossel-Schwabl model has been slightly modified in this work by introducing two parameters (probability of propagation and regrowth) specific for each different class of vegetation cover. Using model selection methods based on AIC, the model with the optimal number of classes with different fire behaviour was selected. Two different case studies are presented in this work: Regione Liguria and Regione Sardegna (Italy). Both regions are situated in the center of the Mediterranean and are characterized by a high number of fires and burned area. However, the two regions have very different fire regimes. Sardinia is affected by the fire phenomenon only in summer whilst Liguria is affected by fires also in winter, with higher number of fires and larger burned area. In addition, the two region are very different in vegetation cover. The presence of Mediterranean conifers, (Pinus Pinaster, Pinus Nigra, Pinus halepensis) is quite spread in Liguria and is limited in Sardinia. What is common in the two regions is the widespread presence of shrub species frequently spread by fire. The analysis in the two regions thus allows in a rather limited area to study almost all the species that characterize the Mediterranean region. This work shows that the fire regime in Mediterranean area is strongly related with vegetation patterns, is almost totally independent by the cause of ignition, and only partially dependent by fire extinguishing actions.

Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli.

PubMed

Yang, Yang; Huang, Jianying; Mis, Malgorzata A; Estacion, Mark; Macala, Lawrence; Shah, Palak; Schulman, Betsy R; Horton, Daniel B; Dib-Hajj, Sulayman D; Waxman, Stephen G

2016-07-13

Voltage-gated sodium channel Nav1.7 is a central player in human pain. Mutations in Nav1.7 produce several pain syndromes, including inherited erythromelalgia (IEM), a disorder in which gain-of-function mutations render dorsal root ganglia (DRG) neurons hyperexcitable. Although patients with IEM suffer from episodes of intense burning pain triggered by warmth, the effects of increased temperature on DRG neurons expressing mutant Nav1.7 channels have not been well documented. Here, using structural modeling, voltage-clamp, current-clamp, and multielectrode array recordings, we have studied a newly identified Nav1.7 mutation, Ala1632Gly, from a multigeneration family with IEM. Structural modeling suggests that Ala1632 is a molecular hinge and that the Ala1632Gly mutation may affect channel gating. Voltage-clamp recordings revealed that the Nav1.7-A1632G mutation hyperpolarizes activation and depolarizes fast-inactivation, both gain-of-function attributes at the channel level. Whole-cell current-clamp recordings demonstrated increased spontaneous firing, lower current threshold, and enhanced evoked firing in rat DRG neurons expressing Nav1.7-A1632G mutant channels. Multielectrode array recordings further revealed that intact rat DRG neurons expressing Nav1.7-A1632G mutant channels are more active than those expressing Nav1.7 WT channels. We also showed that physiologically relevant thermal stimuli markedly increase the mean firing frequencies and the number of active rat DRG neurons expressing Nav1.7-A1632G mutant channels, whereas the same thermal stimuli only increase these parameters slightly in rat DRG neurons expressing Nav1.7 WT channels. The response of DRG neurons expressing Nav1.7-A1632G mutant channels upon increase in temperature suggests a cellular basis for warmth-triggered pain in IEM. Inherited erythromelalgia (IEM), a severe pain syndrome characterized by episodes of intense burning pain triggered by warmth, is caused by mutations in sodium channel Nav1.7, which are preferentially expressed in sensory and sympathetic neurons. More than 20 gain-of-function Nav1.7 mutations have been identified from IEM patients, but the question of how warmth triggers episodes of pain in IEM has not been well addressed. Combining multielectrode array, voltage-clamp, and current-clamp recordings, we assessed a newly identified IEM mutation (Nav1.7-A1632G) from a multigeneration family. Our data demonstrate gain-of-function attributes at the channel level and differential effects of physiologically relevant thermal stimuli on the excitability of DRG neurons expressing mutant and WT Nav1.7 channels, suggesting a cellular mechanism for warmth-triggered pain episodes in IEM patients. Copyright © 2016 the authors 0270-6474/16/367512-12$15.00/0.

The relationship between cognitive function, depressive behaviour and sleep quality with 24-h urinary sodium excretion in patients with essential hypertension.

PubMed

Afsar, Baris

2013-03-01

Various studies have shown that sodium intake is related to increased blood pressure. However, the relationship between sodium intake and cognitive function and depression has not previously been studied. The objective of this study was to investigate the relationship between 24-h sodium excretion with cognitive function, depression and sleep quality in patients newly diagnosed with essential hypertension. All patients underwent history taking, physical examination, blood pressure measurement, 12-lead ECG evaluation, routine urine analysis, biochemical analysis and 24-h urine collection to measure urinary sodium and protein excretion and creatinine clearance, evaluation of cognitive function, depressive behaviour and sleep quality. In total, 119 patients newly diagnosed with essential hypertension (50 men and 69 women aged 54.2 ± 16.1 years) were enrolled. The 24-h urinary sodium excretion of the patients was 204.0 ± 240.4 mEq/day. The Standardized Mini Mental State Examination (SMMSE), Pittsburgh Sleep Quality Index and Beck Depression Inventory scores of the patients were 26.0 ± 2.7, 5.6 ± 3.1 and 21.6 ± 13.5, respectively. Spearman correlation analysis revealed that 24-h urinary sodium excretion was correlated with age (rho -0.258, p = 0.005), systolic blood pressure (rho 0.219, p = 0.017), diastolic blood pressure (rho 0.195, p = 0.034), creatinine clearance (rho 0.414, p < 0.0001) and SMMSE score (rho -0.257, p = 0.005). Stepwise linear regression of independent factors revealed that gender (p < 0.0001), creatinine clearance (p < 0.0001), systolic blood pressure (p = 0.031) and SMMSE score (p < 0.0001) were independently related to logarithmically converted 24-h sodium excretion. The current study demonstrated that better cognitive function, but not depressive behaviour and sleep disturbance, is related to decreased sodium intake as evaluated by 24-h urinary sodium excretion. Studies are needed to highlight the mechanisms regarding the relationship between cognitive function and sodium intake.

Assessment of dietary sodium intake using a food frequency questionnaire and 24-hour urinary sodium excretion: a systematic literature review.

PubMed

McLean, Rachael M; Farmer, Victoria L; Nettleton, Alice; Cameron, Claire M; Cook, Nancy R; Campbell, Norman R C

2017-12-01

Food frequency questionnaires (FFQs) are often used to assess dietary sodium intake, although 24-hour urinary excretion is the most accurate measure of intake. The authors conducted a systematic review to investigate whether FFQs are a reliable and valid way of measuring usual dietary sodium intake. Results from 18 studies are described in this review, including 16 validation studies. The methods of study design and analysis varied widely with respect to FFQ instrument, number of 24-hour urine collections collected per participant, methods used to assess completeness of urine collections, and statistical analysis. Overall, there was poor agreement between estimates from FFQ and 24-hour urine. The authors suggest a framework for validation and reporting based on a consensus statement (2004), and recommend that all FFQs used to estimate dietary sodium intake undergo validation against multiple 24-hour urine collections. ©2017 Wiley Periodicals, Inc.

Test Planning, Collection, and Analysis of Pressure Data Resulting from Army Weapon Systems. Volume IV. Data Analysis of the M198 and M109 May 1979 Firings.

DTIC Science & Technology

1980-05-01

the M203 charge during May 1979 at Aberdeen Proving Ground . The data collection and analysis effort is part of a continuing program undertaken by...May to 18 May 1979 the M198 towed howitzer and the M109 self- propelled howitzer were fired with the 14203 charge at the Aberdeen Proving Grounds ...howitzer and the M109 self- propeiled howitzer were fired with the M203 charge at the Aberdeen Proving Grounds . This section of the report gives the

Thermal analysis of GFRP-reinforced continuous concrete decks subjected to top fire

NASA Astrophysics Data System (ADS)

Hawileh, Rami A.; Rasheed, Hayder A.

2017-12-01

This paper presents a numerical study that investigates the behavior of continuous concrete decks doubly reinforced with top and bottom glass fiber reinforced polymer (GFRP) bars subjected to top surface fire. A finite element (FE) model is developed and a detailed transient thermal analysis is performed on a continuous concrete bridge deck under the effect of various fire curves. A parametric study is performed to examine the top cover thickness and the critical fire exposure curve needed to fully degrade the top GFRP bars while achieving certain fire ratings for the deck considered. Accordingly, design tables are prepared for each fire curve to guide the engineer to properly size the top concrete cover and maintain the temperature in the GFRP bars below critical design values in order to control the full top GFRP degradation. It is notable to indicate that degradation of top GFRP bars do not pose a collapse hazard but rather a serviceability concern since cracks in the negative moment region widen resulting in simply supported spans.

Evaluation of a headspace solid-phase microextraction method for the analysis of ignitable liquids in fire debris.

PubMed

Fettig, Ina; Krüger, Simone; Deubel, Jan H; Werrel, Martin; Raspe, Tina; Piechotta, Christian

2014-05-01

The chemical analysis of fire debris represents a crucial part in fire investigations to determine the cause of a fire. A headspace solid-phase microextraction (HS-SPME) procedure for the detection of ignitable liquids in fire debris using a fiber coated with a mixture of three different sorbent materials (Divinylbenzene/Carboxen/Polydimethylsiloxane, DVB/CAR/PDMS) is described. Gasoline and diesel fuel were spiked upon a preburnt matrix (wood charcoal), extracted and concentrated with HS-SPME and then analyzed with gas chromatography/mass spectrometry (GC/MS). The experimental conditions--extraction temperature, incubation and exposure time--were optimized. To assess the applicability of the method, fire debris samples were prepared in the smoke density chamber (SDC) and a controlled-atmosphere cone calorimeter. The developed methods were successfully applied to burnt particleboard and carpet samples. The results demonstrate that the procedure that has been developed here is suitable for detecting these ignitable liquids in highly burnt debris. © 2013 American Academy of Forensic Sciences.

Co-variability of smoke and fire in the Amazon basin

NASA Astrophysics Data System (ADS)

Mishra, Amit Kumar; Lehahn, Yoav; Rudich, Yinon; Koren, Ilan

2015-05-01

The Amazon basin is a hot spot of anthropogenically-driven biomass burning, accounting for approximately 15% of total global fire emissions. It is essential to accurately measure these fires for robust regional and global modeling of key environmental processes. Here we have explored the link between spatio-temporal variability patterns in the Amazon basin's fires and the resulting smoke loading using 11 years (2002-2012) of data from the Moderate Resolution Imaging Spectroradiometer (MODIS) and the Aerosol Robotic Network (AERONET) observations. Focusing on the peak burning season (July-October), our analysis shows strong inter-annual correlation between aerosol optical depth (AOD) and two MODIS fire products: fire radiative power (FRP) and fire pixel counts (FC). Among these two fire products, the FC better indicates the amount of smoke in the basin, as represented in remotely sensed AOD data. This fire product is significantly correlated both with regional AOD retrievals from MODIS and with point AOD measurements from the AERONET stations, pointing to spatial homogenization of the smoke over the basin on a seasonal time scale. However, MODIS AODs are found better than AERONET AODs observation for linking between smoke and fire. Furthermore, MODIS AOD measurements are strongly correlated with number of fires ∼10-20 to the east, most likely due to westward advection of smoke by the wind. These results can be rationalized by the regional topography and the wind regimes. Our analysis can improve data assimilation of satellite and ground-based observations into regional and global model studies, thus improving the assessment of the environmental and climatic impacts of frequency and distribution variability of the Amazon basin's fires. We also provide the optimal spatial and temporal scales for ground-based observations, which could be used for such applications.

Valuing fire planning alternatives in forest restoration: using derived demand to integrate economics with ecological restoration.

PubMed

Rideout, Douglas B; Ziesler, Pamela S; Kernohan, Nicole J

2014-08-01

Assessing the value of fire planning alternatives is challenging because fire affects a wide array of ecosystem, market, and social values. Wildland fire management is increasingly used to address forest restoration while pragmatic approaches to assessing the value of fire management have yet to be developed. Earlier approaches to assessing the value of forest management relied on connecting site valuation with management variables. While sound, such analysis is too narrow to account for a broad range of ecosystem services. The metric fire regime condition class (FRCC) was developed from ecosystem management philosophy, but it is entirely biophysical. Its lack of economic information cripples its utility to support decision-making. We present a means of defining and assessing the deviation of a landscape from its desired fire management condition by re-framing the fire management problem as one of derived demand. This valued deviation establishes a performance metric for wildland fire management. Using a case study, we display the deviation across a landscape and sum the deviations to produce a summary metric. This summary metric is used to assess the value of alternative fire management strategies on improving the fire management condition toward its desired state. It enables us to identify which sites are most valuable to restore, even when they are in the same fire regime condition class. The case study site exemplifies how a wide range of disparate values, such as watershed, wildlife, property and timber, can be incorporated into a single landscape assessment. The analysis presented here leverages previous research on environmental capital value and non-market valuation by integrating ecosystem management, restoration, and microeconomics. Copyright © 2014 Elsevier Ltd. All rights reserved.

Catalytic and inhibiting effects of lithium peroxide and hydroxide on sodium chlorate decomposition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cannon, J.C.; Zhang, Y.

1995-09-01

Chemical oxygen generators based on sodium chlorate and lithium perchlorate are used in airplanes, submarines, diving, and mine rescue. Catalytic decomposition of sodium chlorate in the presence of cobalt oxide, lithium peroxide, and lithium hydroxide is studied using thermal gravimetric analysis. Lithium peroxide and hydroxide are both moderately active catalysts for the decomposition of sodium chlorate when used alone, and inhibitors when used with the more active catalyst cobalt oxide.

Challenges in sodium intake reduction and meal consumption patterns among participants with metabolic syndrome in a dietary trial.

PubMed

Wang, Jinsong; Olendzki, Barbara C; Wedick, Nicole M; Persuitte, Gioia M; Culver, Annie L; Li, Wenjun; Merriam, Philip A; Carmody, James; Fang, Hua; Zhang, Zhiying; Olendzki, Gin-Fei; Zheng, Liang; Ma, Yunsheng

2013-12-18

Dietary guidelines suggest limiting daily sodium intake to <2,300 mg for the general population, and <1,500 mg/d for those with certain cardiovascular risk factors. Despite these recommendations, few Americans are able to achieve this goal. Identifying challenges in meeting these guidelines is integral for successful compliance. This analysis examined patterns and amount of daily sodium intake among participants with metabolic syndrome enrolled in a one-year dietary intervention study. Two hundred forty participants with metabolic syndrome enrolled in a dietary intervention trial to lose weight and improve dietary quality. Three 24-hour dietary recalls were collected at each visit which provided meal patterns and nutrient data, including sodium intake. A secondary data analysis was conducted to examine sodium consumption patterns at baseline and at one-year study visits. Sodium consumption patterns over time were examined using linear mixed models. The percentage of meals reported eaten in the home at both baseline and one-year follow-up was approximately 69%. Follow-up for the one-year dietary intervention revealed that the participants who consumed sodium greater than 2,300 mg/d declined from 75% (at baseline) to 59%, and those that consumed higher than 1,500 mg/d declined from 96% (at baseline) to 85%. Average sodium intake decreased from 2,994 mg at baseline to 2,558 mg at one-year (P < 0.001), and the sodium potassium ratio also decreased from 1.211 to 1.047 (P < 0.001). Sodium intake per meal varied significantly by meal type, location, and weekday, with higher intake at dinner, in restaurants, and on weekends. At-home lunch and dinner sodium intake decreased (P < 0.05), while dinner sodium intake at restaurant/fast food chains increased from baseline to one-year (P < 0.05). Sodium intake for the majority of participants exceeded the recommended dietary guidelines. Findings support actions that encourage low-sodium food preparation at home and encourage public health policies that decrease sodium in restaurants and prepared foods.

Challenges in sodium intake reduction and meal consumption patterns among participants with metabolic syndrome in a dietary trial

PubMed Central

2013-01-01

Background Dietary guidelines suggest limiting daily sodium intake to <2,300 mg for the general population, and <1,500 mg/d for those with certain cardiovascular risk factors. Despite these recommendations, few Americans are able to achieve this goal. Identifying challenges in meeting these guidelines is integral for successful compliance. This analysis examined patterns and amount of daily sodium intake among participants with metabolic syndrome enrolled in a one-year dietary intervention study. Methods Two hundred forty participants with metabolic syndrome enrolled in a dietary intervention trial to lose weight and improve dietary quality. Three 24-hour dietary recalls were collected at each visit which provided meal patterns and nutrient data, including sodium intake. A secondary data analysis was conducted to examine sodium consumption patterns at baseline and at one-year study visits. Sodium consumption patterns over time were examined using linear mixed models. Results The percentage of meals reported eaten in the home at both baseline and one-year follow-up was approximately 69%. Follow-up for the one-year dietary intervention revealed that the participants who consumed sodium greater than 2,300 mg/d declined from 75% (at baseline) to 59%, and those that consumed higher than 1,500 mg/d declined from 96% (at baseline) to 85%. Average sodium intake decreased from 2,994 mg at baseline to 2,558 mg at one-year (P < 0.001), and the sodium potassium ratio also decreased from 1.211 to 1.047 (P < 0.001). Sodium intake per meal varied significantly by meal type, location, and weekday, with higher intake at dinner, in restaurants, and on weekends. At-home lunch and dinner sodium intake decreased (P < 0.05), while dinner sodium intake at restaurant/fast food chains increased from baseline to one-year (P < 0.05). Conclusion Sodium intake for the majority of participants exceeded the recommended dietary guidelines. Findings support actions that encourage low-sodium food preparation at home and encourage public health policies that decrease sodium in restaurants and prepared foods. PMID:24345027

Design and realization of disaster assessment algorithm after forest fire

NASA Astrophysics Data System (ADS)

Xu, Aijun; Wang, Danfeng; Tang, Lihua

2008-10-01

Based on GIS technology, this paper mainly focuses on the application of disaster assessment algorithm after forest fire and studies on the design and realization of disaster assessment based on GIS. After forest fire through the analysis and processing of multi-sources and heterogeneous data, this paper integrates the foundation that the domestic and foreign scholars laid of the research on assessment for forest fire loss with the related knowledge of assessment, accounting and forest resources appraisal so as to study and approach the theory framework and assessment index of the research on assessment for forest fire loss. The technologies of extracting boundary, overlay analysis, and division processing of multi-sources spatial data are available to realize the application of the investigation method of the burnt forest area and the computation of the fire area. The assessment provides evidence for fire cleaning in burnt areas and new policy making on restoration in terms of the direct and the indirect economic loss and ecological and environmental damage caused by forest fire under the condition of different fire danger classes and different amounts of forest accumulation, thus makes forest resources protection operated in a faster, more efficient and more economical way. Finally, this paper takes Lin'an city of Zhejiang province as a test area to confirm the method mentioned in the paper in terms of key technologies.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uchibori, Akihiro; Kurihara, Akikazu; Ohshima, Hiroyuki

A multiphysics analysis system for sodium-water reaction phenomena in a steam generator of sodium-cooled fast reactors was newly developed. The analysis system consists of the mechanistic numerical analysis codes, SERAPHIM, TACT, and RELAP5. The SERAPHIM code calculates the multicomponent multiphase flow and sodium-water chemical reaction caused by discharging of pressurized water vapor. Applicability of the SERAPHIM code was confirmed through the analyses of the experiment on water vapor discharging in liquid sodium. The TACT code was developed to calculate heat transfer from the reacting jet to the adjacent tube and to predict the tube failure occurrence. The numerical models integratedmore » into the TACT code were verified through some related experiments. The RELAP5 code evaluates thermal hydraulic behavior of water inside the tube. The original heat transfer correlations were corrected for the tube rapidly heated by the reacting jet. The developed system enables evaluation of the wastage environment and the possibility of the failure propagation.« less

Increased dietary sodium is independently associated with greater mortality among prevalent hemodialysis patients

PubMed Central

Mc Causland, Finnian R.; Waikar, Sushrut S.; Brunelli, Steven M.

2013-01-01

Dietary sodium is thought to play a major role in the pathogenesis of hypertension, hypervolemia and mortality in hemodialysis patients. Thus, restriction is almost universally recommended. However, the evidence on which these assumptions are based is limited. We undertook a post-hoc analysis of the Hemodialysis Study with available dietary, clinical and laboratory information. Linear regression models were fit to estimate associations of dietary sodium with ultrafiltration requirement, blood pressure and nutritional indices. Cox regression models were fit to estimate the association of dietary sodium intake, sodium:calorie intake, sodium:potassium intake and prescribed sodium restriction with all-cause mortality. Complete data were available in 1770 subjects, of whom 44% were male, 63% were black and 44% were diabetic. Mean age was 58 (±14) years; median dietary sodium intake was 2080 (IQR: 1490-2850) mg/day. After case-mix adjustment, higher reported dietary sodium was associated with greater ultrafiltration requirement, caloric and protein intake; sodium:calorie intake ratio associated with greater UF requirement; sodium:potassium ratio associated with higher serum sodium. None were associated with pre-dialysis systolic blood pressure. Higher baseline reported dietary sodium, sodium:calorie ratio and sodium:potassium ratio were independently associated with greater all-cause mortality. No associations between prescribed dietary sodium restriction and mortality were observed. Higher reported dietary sodium intake is independently associated with greater mortality among prevalent hemodialysis subjects. Randomized trials are warranted to determine whether dietary sodium restriction improves survival. PMID:22418981

Spectral Mixture Analysis to map burned areas in Brazil's deforestation arc from 1992 to 2011

NASA Astrophysics Data System (ADS)

Antunes Daldegan, G.; Ribeiro, F.; Roberts, D. A.

2017-12-01

The two most extensive biomes in South America, the Amazon and the Cerrado, are subject to several fire events every dry season. Both are known for their ecological and environmental importance. However, due to the intensive human occupation over the last four decades, they have been facing high deforestation rates. The Cerrado biome is adapted to fire and is considered a fire-dependent landscape. In contrast, the Amazon as a tropical moist broadleaf forest does not display similar characteristics and is classified as a fire-sensitive landscape. Nonetheless, studies have shown that forest areas that have already been burned become more prone to experience recurrent burns. Remote sensing has been extensively used by a large number of researchers studying fire occurrence at a global scale, as well as in both landscapes aforementioned. Digital image processing aiming to map fire activity has been applied to a number of imagery from sensors of various spatial, temporal, and spectral resolutions. More specifically, several studies have used Landsat data to map fire scars in the Amazon forest and in the Cerrado. An advantage of using Landsat data is the potential to map fire scars at a finer spatial resolution, when compared to products derived from imagery of sensors featuring better temporal resolution but coarser spatial resolution, such as MODIS (Moderate Resolution Imaging Spectrometer) and GOES (Geostationary Operational Environmental Satellite). This study aimed to map burned areas present in the Amazon-Cerrado transition zone by applying Spectral Mixture Analysis on Landsat imagery for a period of 20 years (1992-2011). The study area is a subset of this ecotone, centered at the State of Mato Grosso. By taking advantage of the Landsat 5TM and Landsat 7ETM+ imagery collections available in Google Earth Engine platform and applying Spectral Mixture Analysis (SMA) techniques over them permitted to model fire scar fractions and delimitate burned areas. Overlaying yearly burned areas allowed to identify areas with high fire recurrence.

Analysis of geometric moments as features for firearm identification.

PubMed

Md Ghani, Nor Azura; Liong, Choong-Yeun; Jemain, Abdul Aziz

2010-05-20

The task of identifying firearms from forensic ballistics specimens is exacting in crime investigation since the last two decades. Every firearm, regardless of its size, make and model, has its own unique 'fingerprint'. These fingerprints transfer when a firearm is fired to the fired bullet and cartridge case. The components that are involved in producing these unique characteristics are the firing chamber, breech face, firing pin, ejector, extractor and the rifling of the barrel. These unique characteristics are the critical features in identifying firearms. It allows investigators to decide on which particular firearm that has fired the bullet. Traditionally the comparison of ballistic evidence has been a tedious and time-consuming process requiring highly skilled examiners. Therefore, the main objective of this study is the extraction and identification of suitable features from firing pin impression of cartridge case images for firearm recognition. Some previous studies have shown that firing pin impression of cartridge case is one of the most important characteristics used for identifying an individual firearm. In this study, data are gathered using 747 cartridge case images captured from five different pistols of type 9mm Parabellum Vektor SP1, made in South Africa. All the images of the cartridge cases are then segmented into three regions, forming three different set of images, i.e. firing pin impression image, centre of firing pin impression image and ring of firing pin impression image. Then geometric moments up to the sixth order were generated from each part of the images to form a set of numerical features. These 48 features were found to be significantly different using the MANOVA test. This high dimension of features is then reduced into only 11 significant features using correlation analysis. Classification results using cross-validation under discriminant analysis show that 96.7% of the images were classified correctly. These results demonstrate the value of geometric moments technique for producing a set of numerical features, based on which the identification of firearms are made.

Targeting Audiences and Content for Forest Fire Information Programs.

ERIC Educational Resources Information Center

Carpenter, Edwin H.; And Others

1986-01-01

Discusses opinion survey results for the purpose of improving the capabilities of forest managers to effectively communicate new fire management objectives and plans. Includes recommendations based on the analysis concerning the appropriate audiences and content to target in the design of fire information programs. (ML)

41 CFR 102-80.110 - What must an equivalent level of safety analysis indicate?

Code of Federal Regulations, 2014 CFR

2014-01-01

..., and reliability of all building systems impacting fire growth, occupant knowledge of the fire, and... Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 80-SAFETY AND ENVIRONMENTAL MANAGEMENT Accident and Fire Prevention Equivalent Level of Safety...

41 CFR 102-80.110 - What must an equivalent level of safety analysis indicate?

Code of Federal Regulations, 2013 CFR

2013-07-01

..., and reliability of all building systems impacting fire growth, occupant knowledge of the fire, and... Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 80-SAFETY AND ENVIRONMENTAL MANAGEMENT Accident and Fire Prevention Equivalent Level of Safety...

41 CFR 102-80.110 - What must an equivalent level of safety analysis indicate?

Code of Federal Regulations, 2011 CFR

2011-01-01

..., and reliability of all building systems impacting fire growth, occupant knowledge of the fire, and... Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 80-SAFETY AND ENVIRONMENTAL MANAGEMENT Accident and Fire Prevention Equivalent Level of Safety...

41 CFR 102-80.110 - What must an equivalent level of safety analysis indicate?

Code of Federal Regulations, 2012 CFR

2012-01-01

..., and reliability of all building systems impacting fire growth, occupant knowledge of the fire, and... Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 80-SAFETY AND ENVIRONMENTAL MANAGEMENT Accident and Fire Prevention Equivalent Level of Safety...

Fire Protection. Honeywell Planning Guide.

ERIC Educational Resources Information Center

Honeywell, Inc., Minneapolis, Minn.

A general discussion of fire alarms and protection is provided by a manufacturer of automated monitoring and control systems. Background information describes old and new fire alarm systems, comparing system components, wage savings, and cost analysis. Different kinds of automatic systems are listed, including--(1) local system, (2) auxiliary…

Motorcoach fire safety analysis : the causes, frequency, and severity of motorcoach fires in the United States

DOT National Transportation Integrated Search

2012-06-28

The Federal Motor Carrier Safety Administrations (FMCSA) mission is to reduce crashes, injuries, and fatalities on our nations roads involving motor vehicles, and to further its work the agency set out to identify ways to reduce motorcoach fire...

Analysis of Gold Ores by Fire Assay

ERIC Educational Resources Information Center

Blyth, Kristy M.; Phillips, David N.; van Bronswijk, Wilhelm

2004-01-01

Students of an Applied Chemistry degree course carried out a fire-assay exercise. The analysis showed that the technique was a worthwhile quantitative analytical technique and covered interesting theory including acid-base and redox chemistry and other concepts such as inquarting and cupelling.

Using prescribed fire to reduce the risk of large wildfires: A break-even analysis

Treesearch

James M. Saveland

1987-01-01

Nearly all wildfires are extinguished when they are still small. The 3-5% that get out of control cause 95% of all wildfire-related costs and damages (Dodge 1972, Wilson 1985). There are two ways to deal with these problem fires. One practice is to limit fire by suppressing fires as soon as possible after they are detected. Increasing the capability of suppression...

Solution of Fire Protection in Historic Buildings

NASA Astrophysics Data System (ADS)

Iringová, Agnes; Idunk, Róbert

2016-12-01

The paper introduces optimization of the functional use of renovated spaces in historic buildings in terms of fire risk. It brings assessment of fire protection in the folk house Habánsky Dvor, situated in the village of Veľké Leváre, whose function was changed into the museum. It goes into static analysis of existing load-bearing structures and assessment of their fire resistance according to Eurocodes.

Wildland fire risk and social vulnerability in the Southeastern United States: An exploratory spatial data analysis approach

Treesearch

Cassandra Johnson Gaither; N.C. Poudyal; S. Goodrick; J.M. Bowker; S. Malone; J. Gan

2011-01-01

The southeastern U.S. is one of the more wildland fire prone areas of the country and also contains some of the poorest or most socially vulnerable rural communities. Our project addresses wildland fire risk in this part of the U.S and its intersection with social vulnerability. We examine spatial association between high wildland fire prone areas which also rank high...

Sodium content in processed foods in Argentina: compliance with the national law.

PubMed

Allemandi, Lorena; Tiscornia, María Victoria; Ponce, Miguel; Castronuovo, Luciana; Dunford, Elizabeth; Schoj, Verónica

2015-06-01

Despite the body of evidence that documents the unfavorable effects of excessive sodium consumption on blood pressure and cardiovascular health, public health efforts to decrease sodium consumption have been limited to a few countries. Argentina is the first country in Latin America to regulate sodium content of processed foods by means of a national law. The objective of this cross-sectional quantitative study is to provide a baseline comparison against the reduction targets set by the national law before its entry into force. Data were collected in February 2014 in a leading supermarket chain located in Buenos Aires. Nutrient data from package labels were analysed for 1,320 products within 14 food groups during the study period. To compare sodium concentration levels with the established maximum levels we matched the collected food groups with the food groups included in the law resulting in a total of 292 products. Data analysis was conducted using SPSS version 20 software. Food groups with the highest median sodium content were sauces and spreads (866.7 mg/100 g), meat and meat products (750 mg/100 g) and snack foods (644 mg/100 g). Categories with the highest sodium content were appetizers (1,415 mg/100 g), sausages (1,050 mg/100 g) and ready-made meals (940.7 mg/100 g). We also found large variability within products from the same food categories. Products included in the national law correspond to 22.1% (n=292) of the surveyed foods. From the 18 food groups, 15 showed median sodium values below the established targets. Products exceeding the established maximum levels correspond to 15.1% (n=44) of the products included in the analysis. This study is the first analysis of food labels to determine sodium concentrations of processed foods in Argentina and to provide a baseline against the national law standards. Upon the completion of this analysis, maximum levels have been achieved by most of the food groups included in the law. Thus, the introduction of further reductions for the existing maximum levels and the establishment of sodium targets for all relevant product categories not included in the law should be considered as the next steps in the process.

Estimation of carbon emissions from wildfires in Alaskan boreal forests using AVHRR data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kasischke, E.S.; French, N.H.F.; Bourgeau-Chavez, L.L

1993-06-01

The objectives of this research study were to evaluate the utility of using AVHRR data for locating and measuring the areal extent of wildfires in the boreal forests of Alaska and to estimate the amount of carbon being released during these fires. Techniques were developed to using the normalized difference vegetation signature derived from AVHRR data to detect and measure the area of fires in Alaska. A model was developed to estimate the amount of biomass/carbon being stored in Alaskan boreal forests, and the amount of carbon released during fires. The AVHRR analysis resulted in detection of > 83% ofmore » all forest fires greater than 2,000 ha in size in the years 1990 and 1991. The areal estimate derived from AVHRR data were 75% of the area mapped by the Alaska Fire Service for these years. Using fire areas and locations for 1954 through 1992, it was determined that on average, 13.0 gm-C-m-2 of boreal forest area is released during fires every year. This estimate is two to six times greater than previous reported estimates. Our conclusions are that the analysis of AVHRR data represents a viable means for detecting and mapping fires in boreal regions on a global basis.« less

Climate, not Aboriginal landscape burning, controlled the historical demography and distribution of fire-sensitive conifer populations across Australia

PubMed Central

Sakaguchi, Shota; Bowman, David M. J. S.; Prior, Lynda D.; Crisp, Michael D.; Linde, Celeste C.; Tsumura, Yoshihiko; Isagi, Yuji

2013-01-01

Climate and fire are the key environmental factors that shape the distribution and demography of plant populations in Australia. Because of limited palaeoecological records in this arid continent, however, it is unclear as to which factor impacted vegetation more strongly, and what were the roles of fire regime changes owing to human activity and megafaunal extinction (since ca 50 kya). To address these questions, we analysed historical genetic, demographic and distributional changes in a widespread conifer species complex that paradoxically grows in fire-prone regions, yet is very sensitive to fire. Genetic demographic analysis showed that the arid populations experienced strong bottlenecks, consistent with range contractions during the Last Glacial Maximum (ca 20 kya) predicted by species distribution models. In southern temperate regions, the population sizes were estimated to have been mostly stable, followed by some expansion coinciding with climate amelioration at the end of the last glacial period. By contrast, in the flammable tropical savannahs, where fire risk is the highest, demographic analysis failed to detect significant population bottlenecks. Collectively, these results suggest that the impact of climate change overwhelmed any modifications to fire regimes by Aboriginal landscape burning and megafaunal extinction, a finding that probably also applies to other fire-prone vegetation across Australia. PMID:24174110

Forest fires in Italy: An econometric analysis of major driving factors

NASA Astrophysics Data System (ADS)

Michetti, Melania; Pinar, Mehmet

2013-04-01

Despite the relevant fire risk to which Italy is subject from north to south, very few analysis focus on this area. This article investigates the causes of forest fires frequency and intensity in Italy during the first decade of the XXI century. The dynamical aspects of fire danger are explored through the use of panel data techniques which fully capture the impacts on forest fires of changes in both socio-economic and climatic conditions. Italy is treated as a unique region in a first model specification, while it is then split into 3 geographical areas (north, centre, and south) to capture locally specific aspects. Two different dependent variables are alternatively employed and a number of ad hoc tests are performed to corroborate the robustness of our estimates. Results highlight the importance of considering the fire situation separately for the northern, central, and southern parts of Italy. While the presence of railway networks positively affects fire risk, the impact of livestock depends on its specific composition. Favourable effects in fire reduction are represented by the increase in education levels (north and centre) and touristic flows (north and south), and by the containment of illegal activities (south). Weather patterns appear to be important determinants all over the Italian peninsula.

Performance of concrete members subjected to large hydrocarbon pool fires

DOE PAGES

Zwiers, Renata I.; Morgan, Bruce J.

1989-01-01

The authors discuss an investigation to determine analytically if the performance of concrete beams and columns in a hydrocarbon pool test fire would differ significantly from their performance in a standard test fire. The investigation consisted of a finite element analysis to obtain temperature distributions in typical cross sections, a comparison of the resulting temperature distribution in the cross section, and a strength analysis of a beam based on temperature distribution data. Results of the investigation are reported.

Learning by Erring: fire!

PubMed

Bjugn, Roger; Hansen, Jarle

2013-08-01

Biorepositories may be affected by a number of emergencies ranging from bad publicity to natural disasters, and biorepositories should have plans for handling such situations. The emergency management process includes all phases from mitigation to recovery. Fire is one disaster that may cause extensive damage to both physical structures and humans. In this article, we analyze events related to a fire in a storage facility for mechanical freezers. The analysis covers both the pre-crisis stage, the fire itself, and the post-crisis stage. Even the best intended planning cannot stop a crisis from happening. However, an open-minded analysis of the crisis with focus on learning and quality improvement can improve an organization's ability to handle the next emergency situation.

Interactions among wildland fires in a long-established Sierra Nevada natural fire area

USGS Publications Warehouse

Collins, B.M.; Miller, J.D.; Thode, A.E.; Kelly, M.; van Wagtendonk, J.W.; Stephens, S.L.

2009-01-01

We investigate interactions between successive naturally occurring fires, and assess to what extent the environments in which fires burn influence these interactions. Using mapped fire perimeters and satellite-based estimates of post-fire effects (referred to hereafter as fire severity) for 19 fires burning relatively freely over a 31-year period, we demonstrate that fire as a landscape process can exhibit self-limiting characteristics in an upper elevation Sierra Nevada mixed conifer forest. We use the term 'self-limiting' to refer to recurring fire as a process over time (that is, fire regime) consuming fuel and ultimately constraining the spatial extent and lessening fire-induced effects of subsequent fires. When the amount of time between successive adjacent fires is under 9 years, and when fire weather is not extreme (burning index <34.9), the probability of the latter fire burning into the previous fire area is extremely low. Analysis of fire severity data by 10-year periods revealed a fair degree of stability in the proportion of area burned among fire severity classes (unchanged, low, moderate, high). This is in contrast to a recent study demonstrating increasing high-severity burning throughout the Sierra Nevada from 1984 to 2006, which suggests freely burning fires over time in upper elevation Sierra Nevada mixed conifer forests can regulate fire-induced effects across the landscape. This information can help managers better anticipate short- and long-term effects of allowing naturally ignited fires to burn, and ultimately, improve their ability to implement Wildland Fire Use programs in similar forest types. ?? 2008 Springer Science+Business Media, LLC.

Comparing the performance of residential fire sprinklers with other life-safety technologies.

PubMed

Butry, David T

2012-09-01

Residential fire sprinklers have long proven themselves as life-safety technologies to the fire service community. Yet, about 1% of all one- and two-family dwelling fires occur in homes protected by sprinklers. It has been argued that measured sprinkler performance has ignored factors confounding the relationship between sprinkler use and performance. In this analysis, sprinkler performance is measured by comparing 'like' structure fires, while conditioning on smoke detection technology and neighborhood housing and socioeconomic conditions, using propensity score matching. Results show that residential fire sprinklers protect occupant and firefighter health and safety, and are comparable to other life-safety technologies. Published by Elsevier Ltd.

Forest Fire Management: A Comprehensive And Operational Approach

NASA Astrophysics Data System (ADS)

Fabrizi, Roberto; Perez, Bruno; Gomez, Antonio

2013-12-01

Remote sensing plays an important role in obtaining rapid and complete information on the occurrence and evolution in space and time of forest fires. In this paper, we present a comprehensive study of fire events through Earth Observation data for early warning, crisis monitoring and post-event damage assessment or a synthesis of the fire event, both in a wide spatial range (local to regional) and temporal scale (short to long term). The fire products are stored and distributed by means of a WebGIS and a Geoportal with additional auxiliary geospatial data. These products allow fire managers to perform analysis and decision making in a more comprehensive manner.

Fire-retardant decorative inks for aircraft interiors

NASA Technical Reports Server (NTRS)

Kourtides, D. A.; Nir, Z.; Mikroyannidis, J. A.

1985-01-01

Commercial and experimental fire retardants were screened as potential fire retardants for acrylic printing inks used on aircraft interior sandwich panels. The fire retardants are selected according to their physical properties and their thermostabilities. A criterion for selecting a more stable fire retardant is established. Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) are used to determine thermostabilities. Results show that the fire retardant formulations are more thermally stable than the acrylic ink control. It is determined that an ink formulation containing a brominated phenol and carboxy-terminated butadiene acrylonitrile which has been modified with a brominated polymeric additive (BPA), yields the highest limiting oxygen index (LOI) of all the compounds tested. All of the fire-retardant formulations have a higher oxygen index than the baseline acrylic ink.

Impact of the UK voluntary sodium reduction targets on the sodium content of processed foods from 2006 to 2011: analysis of household consumer panel data.

PubMed

Eyles, Helen; Webster, Jacqueline; Jebb, Susan; Capelin, Cathy; Neal, Bruce; Ni Mhurchu, Cliona

2013-11-01

In 2006 the UK Food Standards Agency (FSA) introduced voluntary sodium reduction targets for more than 80 categories of processed food. Our aim was to determine the impact of these targets on the sodium content of processed foods in the UK between 2006 and 2011. Household consumer panel data (n>18,000 households) were used to calculate crude and sales-weighted mean sodium content for 47,337 products in 2006 and 49,714 products in 2011. Two sample t-tests were used to compare means. A secondary analysis was undertaken to explore reformulation efforts and included only products available for sale in both 2006 and 2011. Between 2006 and 2011 there was an overall mean reduction in crude sodium content of UK foods of -26 mg/100g (p ≤ 0.001), equivalent to a 7% fall (356 mg/100g to 330 mg/100g). The corresponding sales-weighted reduction was -21 mg/100g (-6%). For products available for sale in both years the corresponding reduction was -23 mg/100g (p<0.001) or -7%. The UK FSA voluntary targets delivered a moderate reduction in the mean sodium content of UK processed foods between 2006 and 2011. Whilst encouraging, regular monitoring and review of the UK sodium reduction strategy will be essential to ensure continued progress. © 2013.

Chaparral & Fire Ecology: Role of Fire in Seed Germination.

ERIC Educational Resources Information Center

Steele, Nancy L. C.; Keeley, Jon E.

1991-01-01

An activity that incorporates the concepts of plant structure and function and ecology is described. Students investigate the reasons why some California chaparral seeds germinate only after a fire has burned the surrounding chaparral. The procedure, discussion and analysis questions, expected results, potential problems, and additional activities…

Improving freight fire safety : experiment testing and computer modeling to further development of mist-controlling additives for fire mitigation.

DOT National Transportation Integrated Search

2012-08-01

With the purpose to minimize or prevent crash-induced fires in road and rail transportation, the : current interest in bio-derived and blended transportation fuels is increasing. Based on two years : of preliminary testing and analysis, it appears to...

Fire, Death, and Rebirth: A Metaphoric Analysis of the 1988 Yellowstone Fire Debate.

ERIC Educational Resources Information Center

Hardy-Short, Dayle C.; Short, C. Brant

1995-01-01

Finds that two primary archetypal metaphors--death and rebirth--emerged in the public debate concerning management of the 1988 Yellowstone forest fires. Argues that the crisis brought two competing views of public land management to the forefront: the ecological view, and the human-centered view. (SR)

Influences of coupled fire-atmosphere interaction on wildfire behavior

NASA Astrophysics Data System (ADS)

Linn, R.; Winterkamp, J.; Jonko, A. K.; Runde, I.; Canfield, J.; Parsons, R.; Sieg, C.

2017-12-01

Two-way interactions between fire and the environment affect fire behavior at scales ranging from buoyancy-induced mixing and turbulence to fire-scale circulations that retard or increase fire spread. Advances in computing have created new opportunities for the exploration of coupled fire-atmosphere behavior using numerical models that represent interactions between the dominant processes driving wildfire behavior, including convective and radiative heat transfer, aerodynamic drag and buoyant response of the atmosphere to heat released by the fire. Such models are not practical for operational, faster-than-real-time fire prediction due to their computational and data requirements. However, they are valuable tools for exploring influences of fire-atmosphere feedbacks on fire behavior as they explicitly simulate atmospheric motions surrounding fires from meter to kilometer scales. We use the coupled fire-atmosphere model FIRETEC to gain new insights into aspects of fire behavior that have been observed in the field and laboratory, to carry out sensitivity analysis that is impractical through observations and to pose new hypotheses that can be tested experimentally. Specifically, we use FIRETEC to study the following multi-scale coupled fire-atmosphere interactions: 1) 3D fire-atmosphere interaction that dictates multi-scale fire line dynamics; 2) influence of vegetation heterogeneity and variability in wind fields on predictability of fire spread; 3) fundamental impacts of topography on fire spread. These numerical studies support new conceptual models for the dominant roles of multi-scale fluid dynamics in determining fire spread, including the roles of crosswind fire line-intensity variations on heat transfer to unburned fuels and the role of fire line depth expansion in upslope acceleration of fires.

Physiological characterisation of a pH- and calcium-dependent sodium uptake mechanism in the freshwater crustacean, Daphnia magna.

PubMed

Glover, Chris N; Wood, Chris M

2005-03-01

Daphnia are highly sensitive to sodium metabolism disruption caused by aquatic acidification and ionoregulatory toxicants, due to their finely balanced ion homeostasis. Nine different water chemistries of varying pH (4, 6 and 8) and calcium concentration (0, 0.5 and 1 mmol l(-1)) were used to delineate the mechanism of sodium influx in Daphnia magna. Lowering water pH severely inhibited sodium influx when calcium concentration was high, but transport kinetic analysis revealed a stimulated sodium influx capacity (J(max)) when calcium was absent. At low pH increasing water calcium levels decreased J(max) and raised K(m) (decreased sodium influx affinity), while at high pH the opposite pattern was observed (elevated J(max) and reduced K(m)). These effects on sodium influx were mirrored by changes in whole body sodium levels. Further examination of the effect of calcium on sodium influx showed a severe inhibition of sodium uptake by 100 micromol l(-1) calcium gluconate at both low (50 micromol l(-1)) and high (1000 micromol l(-1)) sodium concentrations. At high sodium concentrations, stimulated sodium influx was noted with elevated calcium levels. These results, in addition to data showing amiloride inhibition of sodium influx (K(i)=180 micromol l(-1)), suggest a mechanism of sodium influx in Daphnia magna that involves the electrogenic 2Na(+)/1H(+) exchanger.

Information Framework of Pervasive Real Time Monitoring System: Case of Peat Land Forest Fires and Air Quality in South Sumatera, Indonesia

NASA Astrophysics Data System (ADS)

Nurmaini, Siti; Firsandaya Malik, Reza; Stiawan, Deris; Firdaus; Saparudin; Tutuko, Bambang

2017-04-01

The information framework aims to holistically address the problems and issues posed by unwanted peat and land fires within the context of the natural environment and socio-economic systems. Informed decisions on planning and allocation of resources can only be made by understanding the landscape. Therefore, information on fire history and air quality impacts must be collected for future analysis. This paper proposes strategic framework based on technology approach with data fusion strategy to produce the data analysis about peat land fires and air quality management in in South Sumatera. The research framework should use the knowledge, experience and data from the previous fire seasons to review, improve and refine the strategies and monitor their effectiveness for the next fire season. Communicating effectively with communities and the public and private sectors in remote and rural landscapes is important, by using smartphones and mobile applications. Tools such as one-stop information based on web applications, to obtain information such as early warning to send and receive fire alerts, could be developed and promoted so that all stakeholders can share important information with each other.

Healthcare costs of burn patients from homes without fire sprinklers

PubMed Central

Banfield, Joanne; Rehou, Sarah; Gomez, Manuel; Redelmeier, Donald A.; Jeschke, Marc G.

2014-01-01

The treatment of burn injuries requires high-cost services for healthcare and society. Automatic fire sprinklers are a preventive measure that can decrease fire injuries, deaths, property damage and environmental toxins. This study’s aim was to conduct a cost-analysis of patients with burn or inhalation injuries due to residential fires, and to compare this to the cost of implementing residential automatic fire sprinklers. We conducted a cohort analysis of adult burn patients admitted to our provincial burn center (1995–2012). Patient demographics and injury characteristics were collected from medical records, and clinical and coroner databases. Resource costs included average cost per day at our intensive care and rehabilitation program, transportation, and property loss. During the study period there were 1,557 residential fire-related deaths province-wide and 1,139 patients were admitted to our provincial burn center due to a flame injury occurring at home. At our burn center, the average cost was CAN$84,678 per patient with a total cost of CAN$96,448,194. All resources totaled CAN$3,605,775,200. This study shows the considerable healthcare costs of burn patients from homes without fire sprinklers. PMID:25412056

Curve Number and Peakflow Responses Following the Cerro Grande Fire on a Small Watershed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Springer, E. P.; Hawkins, Richard H.

The Curve Number (CN) method is routinely used to estimate runoff and peakflows following forest fires, but there has been essentially no literature on the estimated value and temporal variation of CNs following wildland fires. In May 2000, the Cerro Grande Fire burned the headwaters of the major watersheds that cross Los Alamos National Laboratory, and a stream gauging network presented an opportunity to assess CNs following the fire. Analysis of rainfall-runoff events indicated that the pre-fire watershed response was complacent or limited watershed area contributed to runoff. The post-fire response indicated that the complacent behavior continued so the watershedmore » response was not dramatically changed. Peakflows did increase by 2 orders of magnitude following the fire, and this was hypothesized to be a function of increase in runoff volume and changes in watershed network allowing more efficient delivery of runoff. More observations and analyses following fires are needed to support definition of CNs for post-fire response and mitigation efforts.« less

Designing solid-liquid interphases for sodium batteries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choudhury, Snehashis; Wei, Shuya; Ozhabes, Yalcin

Secondary batteries based on earth-abundant sodium metal anodes are desirable for both stationary and portable electrical energy storage. Room-temperature sodium metal batteries are impractical today because morphological instability during recharge drives rough, dendritic electrodeposition. Chemical instability of liquid electrolytes also leads to premature cell failure as a result of parasitic reactions with the anode. Here we use joint density-functional theoretical analysis to show that the surface diffusion barrier for sodium ion transport is a sensitive function of the chemistry of solid–electrolyte interphase. In particular, we find that a sodium bromide interphase presents an exceptionally low energy barrier to ion transport,more » comparable to that of metallic magnesium. We evaluate this prediction by means of electrochemical measurements and direct visualization studies. These experiments reveal an approximately three-fold reduction in activation energy for ion transport at a sodium bromide interphase. Direct visualization of sodium electrodeposition confirms large improvements in stability of sodium deposition at sodium bromide-rich interphases.« less

Green synthesis of gold nanoparticles reduced and stabilized by sodium glutamate and sodium dodecyl sulfate.

PubMed

Cabrera, Gil Felicisimo S; Balbin, Michelle M; Eugenio, Paul John G; Zapanta, Charleo S; Monserate, Juvy J; Salazar, Joel R; Mingala, Claro N

2017-03-18

The Turkevich method has been used for many years in the synthesis of gold nanoparticles. Lately, the use of plant extracts and amino acids has been reported, which is valuable in the field of biotechnology and biomedicine. The AuNPs was synthesized from the reduction of HAuCl4 3H2O by sodium glutamate and stabilized with sodium dodecyl sulfate. The optimum concentrations for sodium glutamate and sodium dodecyl sulfate in the synthesis process were determined. The characteristics of the synthesized AuNPs was analysed through UV-Vis Spectroscopy and SEM. The AuNPs have spherical shape with a mean diameter of approximately 21.62 ± 4.39 nm and is well dispersed. FTIR analysis of the AuNPs reflected that the sulfate head group of sodium dodecyl sulfate is adsorbed at the surface of the AuNPs. Thus, we report herein the synthesis of AuNPs using sodium glutamate and sodium dodecyl sulfate. Copyright © 2017 Elsevier Inc. All rights reserved.

Designing solid-liquid interphases for sodium batteries

DOE PAGES

Choudhury, Snehashis; Wei, Shuya; Ozhabes, Yalcin; ...

2017-10-12

Secondary batteries based on earth-abundant sodium metal anodes are desirable for both stationary and portable electrical energy storage. Room-temperature sodium metal batteries are impractical today because morphological instability during recharge drives rough, dendritic electrodeposition. Chemical instability of liquid electrolytes also leads to premature cell failure as a result of parasitic reactions with the anode. Here we use joint density-functional theoretical analysis to show that the surface diffusion barrier for sodium ion transport is a sensitive function of the chemistry of solid–electrolyte interphase. In particular, we find that a sodium bromide interphase presents an exceptionally low energy barrier to ion transport,more » comparable to that of metallic magnesium. We evaluate this prediction by means of electrochemical measurements and direct visualization studies. These experiments reveal an approximately three-fold reduction in activation energy for ion transport at a sodium bromide interphase. Direct visualization of sodium electrodeposition confirms large improvements in stability of sodium deposition at sodium bromide-rich interphases.« less

Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling.

PubMed

Geha, Paul; Yang, Yang; Estacion, Mark; Schulman, Betsy R; Tokuno, Hajime; Apkarian, A Vania; Dib-Hajj, Sulayman D; Waxman, Stephen G

2016-06-01

There is a need for more effective pharmacotherapy for chronic pain, including pain in inherited erythromelalgia (IEM) in which gain-of-function mutations of sodium channel NaV1.7 make dorsal root ganglion (DRG) neurons hyperexcitable. To determine whether pain in IEM can be attenuated via pharmacotherapy guided by genomic analysis and functional profiling. Pain in 2 patients with IEM due to the NaV1.7 S241T mutation, predicted by structural modeling and functional analysis to be responsive to carbamazepine, was assessed in a double-blind, placebo-controlled study conducted from September 2014 to April 21, 2015. Functional magnetic resonance imaging assessed patterns of brain activity associated with pain during treatment with placebo or carbamazepine. Multielectrode array technology was used to assess the effect of carbamazepine on firing of DRG neurons carrying S241T mutant channels. Behavioral assessment of pain; functional magnetic resonance imaging; and assessment of firing in DRG neurons carrying S241T mutant channels. This study included 2 patients from the same family with IEM and the S241T NaV1.7 mutation. We showed that, as predicted by molecular modeling, thermodynamic analysis, and functional profiling, carbamazepine attenuated pain in patients with IEM due to the S241T NaV1.7 mutation. Patient 1 reported a reduction in mean time in pain (TIP) per day during the 15-day maintenance period, from 424 minutes while taking placebo to 231.9 minutes while taking carbamazepine (400 mg/day), and a reduction in total TIP over the 15-day maintenance period, from 6360 minutes while taking placebo to 3015 minutes while taking carbamazepine. Patient 2 reported a reduction in mean TIP per day during the maintenance period, from 61 minutes while taking placebo to 9.1 minutes while taking carbamazepine (400 mg then 200 mg/day), and a reduction in total TIP, from 915 minutes while taking placebo over the 15-day maintenance period to 136 minutes while taking carbamazepine. Patient 1 reported a reduction of mean episode duration, from 615 minutes while taking placebo to 274.1 minutes while taking carbamazepine, while patient 2 reported a reduction of the mean episode duration from 91.5 minutes while taking placebo to 45.3 minutes while taking carbamazepine. Patient 1, who had a history of night awakenings from pain, reported 101 awakenings owing to pain while taking placebo during the maintenance period and 32 awakenings while taking carbamazepine. Attenuation of pain was paralleled by a shift in brain activity from valuation and pain areas to primary and secondary somatosensory, motor, and parietal attention areas. Firing of DRG neurons expressing the S241T NaV1.7 mutant channel in response to physiologically relevant thermal stimuli was reduced by carbamazepine. Our results demonstrate that pharmacotherapy guided by genomic analysis, molecular modeling, and functional profiling can attenuate neuropathic pain in patients carrying the S241T mutation.

Wildfire spread, hazard and exposure metric raster grids for central Catalonia.

PubMed

Alcasena, Fermín J; Ager, Alan A; Salis, Michele; Day, Michelle A; Vega-Garcia, Cristina

2018-04-01

We provide 40 m resolution wildfire spread, hazard and exposure metric raster grids for the 0.13 million ha fire-prone Bages County in central Catalonia (northeastern Spain) corresponding to node influence grid (NIG), crown fraction burned (CFB) and fire transmission to residential houses (TR). Fire spread and behavior data (NIG, CFB and fire perimeters) were generated with fire simulation modeling considering wildfire season extreme fire weather conditions (97 th percentile). Moreover, CFB was also generated for prescribed fire (Rx) mild weather conditions. The TR smoothed grid was obtained with a geospatial analysis considering large fire perimeters and individual residential structures located within the study area. We made these raster grids available to assist in the optimization of wildfire risk management plans within the study area and to help mitigate potential losses from catastrophic events.

Fire safety distances for open pool fires

NASA Astrophysics Data System (ADS)

Sudheer, S.; Kumar, Lokendra; Manjunath, B. S.; Pasi, Amit; Meenakshi, G.; Prabhu, S. V.

2013-11-01

Fire accidents that carry huge loss with them have increased in the previous two decades than at any time in the history. Hence, there is a need for understanding the safety distances from different fires with different fuels. Fire safety distances are computed for different open pool fires. Diesel, gasoline and hexane are used as fuels for circular pool diameters of 0.5 m, 0.7 m and 1.0 m. A large square pool fire of 4 m × 4 m is also conducted with diesel as a fuel. All the prescribed distances in this study are purely based on the thermal analysis. IR camera is used to get the thermal images of pool fires and there by the irradiance at different locations is computed. The computed irradiance is presented with the threshold heat flux limits for human beings.

Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication

PubMed Central

Graindorge, Dany; Martineau, Sylvain; Machon, Christelle; Arnoux, Philippe; Guitton, Jérôme; Francesconi, Stefania; Frochot, Céline; Sage, Evelyne; Girard, Pierre-Marie

2015-01-01

UVA radiation (320–400 nm) is a major environmental agent that can exert its deleterious action on living organisms through absorption of the UVA photons by endogenous or exogenous photosensitizers. This leads to the production of reactive oxygen species (ROS), such as singlet oxygen (1O2) and hydrogen peroxide (H2O2), which in turn can modify reversibly or irreversibly biomolecules, such as lipids, proteins and nucleic acids. We have previously reported that UVA-induced ROS strongly inhibit DNA replication in a dose-dependent manner, but independently of the cell cycle checkpoints activation. Here, we report that the production of 1O2 by UVA radiation leads to a transient inhibition of replication fork velocity, a transient decrease in the dNTP pool, a quickly reversible GSH-dependent oxidation of the RRM1 subunit of ribonucleotide reductase and sustained inhibition of origin firing. The time of recovery post irradiation for each of these events can last from few minutes (reduction of oxidized RRM1) to several hours (replication fork velocity and origin firing). The quenching of 1O2 by sodium azide prevents the delay of DNA replication, the decrease in the dNTP pool and the oxidation of RRM1, while inhibition of Chk1 does not prevent the inhibition of origin firing. Although the molecular mechanism remains elusive, our data demonstrate that the dynamic of replication is altered by UVA photosensitization of vitamins via the production of singlet oxygen. PMID:26485711

A GIS-based approach for comparative analysis of potential fire risk assessment

NASA Astrophysics Data System (ADS)

Sun, Ying; Hu, Lieqiu; Liu, Huiping

2007-06-01

Urban fires are one of the most important sources of property loss and human casualty and therefore it is necessary to assess the potential fire risk with consideration of urban community safety. Two evaluation models are proposed, both of which are integrated with GIS. One is the single factor model concerning the accessibility of fire passage and the other is grey clustering approach based on the multifactor system. In the latter model, fourteen factors are introduced and divided into four categories involving security management, evacuation facility, construction resistance and fire fighting capability. A case study on campus of Beijing Normal University is presented to express the potential risk assessment models in details. A comparative analysis of the two models is carried out to validate the accuracy. The results are approximately consistent with each other. Moreover, modeling with GIS promotes the efficiency the potential risk assessment.

The application of super wavelet finite element on temperature-pressure coupled field simulation of LPG tank under jet fire

NASA Astrophysics Data System (ADS)

Zhao, Bin

2015-02-01

Temperature-pressure coupled field analysis of liquefied petroleum gas (LPG) tank under jet fire can offer theoretical guidance for preventing the fire accidents of LPG tank, the application of super wavelet finite element on it is studied in depth. First, review of related researches on heat transfer analysis of LPG tank under fire and super wavelet are carried out. Second, basic theory of super wavelet transform is studied. Third, the temperature-pressure coupled model of gas phase and liquid LPG under jet fire is established based on the equation of state, the VOF model and the RNG k-ɛ model. Then the super wavelet finite element formulation is constructed using the super wavelet scale function as interpolating function. Finally, the simulation is carried out, and results show that the super wavelet finite element method has higher computing precision than wavelet finite element method.

Severe Headache or Migraine History Is Inversely Correlated With Dietary Sodium Intake: NHANES 1999–2004

PubMed Central

Pogoda, Janice M.; Gross, Noah B.; Arakaki, Xianghong; Fonteh, Alfred N.; Cowan, Robert P.

2016-01-01

Objective We investigated whether dietary sodium intake from respondents of a national cross‐sectional nutritional study differed by history of migraine or severe headaches. Background Several lines of evidence support a disruption of sodium homeostasis in migraine. Design Our analysis population was 8819 adults in the 1999–2004 National Health and Nutrition Examination Survey (NHANES) with reliable data on diet and headache history. We classified respondents who reported a history of migraine or severe headaches as having probable history of migraine. To reduce the diagnostic conflict from medication overuse headache, we excluded respondents who reported taking analgesic medications. Dietary sodium intake was measured using validated estimates of self‐reported total grams of daily sodium consumption and was analyzed as the residual value from the linear regression of total grams of sodium on total calories. Multivariable logistic regression that accounted for the stratified, multistage probability cluster sampling design of NHANES was used to analyze the relationship between migraine and dietary sodium. Results Odds of probable migraine history decreased with increasing dietary sodium intake (odds ratio = 0.93, 95% confidence interval = 0.87, 1.00, P = .0455). This relationship was maintained after adjusting for age, sex, and body mass index (BMI) with slightly reduced significance (P = .0505). In women, this inverse relationship was limited to those with lower BMI (P = .007), while in men the relationship did not differ by BMI. We likely excluded some migraineurs by omitting frequent analgesic users; however, a sensitivity analysis suggested little effect from this exclusion. Conclusions This study is the first evidence of an inverse relationship between migraine and dietary sodium intake. These results are consistent with altered sodium homeostasis in migraine and our hypothesis that dietary sodium may affect brain extracellular fluid sodium concentrations and neuronal excitability. PMID:27016121

Severe Headache or Migraine History is Inversely Correlated With Dietary Sodium Intake: NHANES 1999-2004.

PubMed

Pogoda, Janice M; Gross, Noah B; Arakaki, Xianghong; Fonteh, Alfred N; Cowan, Robert P; Harrington, Michael G

2016-04-01

We investigated whether dietary sodium intake from respondents of a national cross-sectional nutritional study differed by history of migraine or severe headaches. Several lines of evidence support a disruption of sodium homeostasis in migraine. Our analysis population was 8819 adults in the 1999-2004 National Health and Nutrition Examination Survey (NHANES) with reliable data on diet and headache history. We classified respondents who reported a history of migraine or severe headaches as having probable history of migraine. To reduce the diagnostic conflict from medication overuse headache, we excluded respondents who reported taking analgesic medications. Dietary sodium intake was measured using validated estimates of self-reported total grams of daily sodium consumption and was analyzed as the residual value from the linear regression of total grams of sodium on total calories. Multivariable logistic regression that accounted for the stratified, multistage probability cluster sampling design of NHANES was used to analyze the relationship between migraine and dietary sodium. Odds of probable migraine history decreased with increasing dietary sodium intake (odds ratio = 0.93, 95% confidence interval = 0.87, 1.00, P = .0455). This relationship was maintained after adjusting for age, sex, and body mass index (BMI) with slightly reduced significance (P = .0505). In women, this inverse relationship was limited to those with lower BMI (P = .007), while in men the relationship did not differ by BMI. We likely excluded some migraineurs by omitting frequent analgesic users; however, a sensitivity analysis suggested little effect from this exclusion. This study is the first evidence of an inverse relationship between migraine and dietary sodium intake. These results are consistent with altered sodium homeostasis in migraine and our hypothesis that dietary sodium may affect brain extracellular fluid sodium concentrations and neuronal excitability. © 2016 The Authors Headache published by Wiley Periodicals, Inc. on behalf of American Headache Society.

Effects of added antibiotics on the basic properties of anti-washout-type fast-setting calcium phosphate cement.

PubMed

Takechi, M; Miyamoto, Y; Ishikawa, K; Nagayama, M; Kon, M; Asaoka, K; Suzuki, K

1998-02-01

The effect of added antibiotics on the basic properties of anti-washout-type fast-setting calcium phosphate cement (aw-FSCPC) was investigated in a preliminary evaluation of aw-FSCPC containing drugs. Flomoxef sodium was employed as the antibiotic and was incorporated into the powder-phase aw-FSCPC at up to 10%. The setting time, consistency, wet diametral tensile strength (DTS) value, and porosity were measured for aw-FSCPC containing various amounts of flomoxef sodium. X-ray diffraction (XRD) analysis was also conducted for the identification of products. To evaluate the drug-release profile, set aw-FSCPC was immersed in saline and the released flomoxef sodium was determined at regular intervals. The spread area of the cement paste as an index of consistency of the cement increased progressively with the addition of flomoxef sodium, and it doubled when the aw-FSCPC contained 8% flomoxef sodium. In contrast, the wet DTS value decreased with increase in flomoxef sodium content. Bulk density measurement and scanning electron microscopic observation revealed that the set mass was more porous with the amount of flomoxef sodium contained in the aw-FSCPC. The XRD analysis revealed that formation of hydroxyapatite (HAP) from aw-FSCPC was reduced even after 24 h, when the aw-FSCPC contained flomoxef sodium at > or = 6%. Therefore, the decrease of wet DTS value was thought to be partly the result of the increased porosity and inhibition of HAP formation in aw-FSCPC containing large amounts of flomoxef sodium. The flomoxef sodium release from aw-FSCPC showed the typical profile observed in a skeleton-type drug delivery system (DDS). The rate of drug release from aw-FSCPC can be controlled by changing the concentration of sodium alginate. Although flomoxef sodium addition has certain disadvantageous effects on the basic properties of aw-FSCPC, we conclude that aw-FSCPC is a good candidate for potential use as a DDS carrier that may be useful in surgical operations.

Reconstructing past fire regimes: methods, applications, and relevance to fire management and conservation

NASA Astrophysics Data System (ADS)

Conedera, Marco; Tinner, Willy; Neff, Christophe; Meurer, Manfred; Dickens, Angela F.; Krebs, Patrik

2009-03-01

Biomass burning and resulting fire regimes are major drivers of vegetation changes and of ecosystem dynamics. Understanding past fire dynamics and their relationship to these factors is thus a key factor in preserving and managing present biodiversity and ecosystem functions. Unfortunately, our understanding of the disturbance dynamics of past fires is incomplete, and many open questions exist relevant to these concepts and the related methods. In this paper we describe the present status of the fire-regime concept, discuss the notion of the fire continuum and related proxies, and review the most important existing approaches for reconstructing fire history at centennial to millennial scales. We conclude with a short discussion of selected directions for future research that may lead to a better understanding of past fire-regime dynamics. In particular, we suggest that emphasis should be laid on (1) discriminating natural from anthropogenic fire-regime types, (2) improving combined analysis of fire and vegetation reconstructions to study long-term fire ecology, and (3) overcoming problems in defining temporal and spatial scales of reference, which would allow better use of past records to gain important insights for landscape, fire and forest management.

Development of a Method for Selecting Optimum Sites for the Automatic Mountain Meteorology Observation Station (AMOS) to Improve Predictability of Forest Fires in Inaccessible Area

NASA Astrophysics Data System (ADS)

Yoon, S.; Won, M.; Jang, K.; Lim, J.

2016-12-01

As there has been a recent increase in the case of forest fires in North Korea descending southward through the De-Militarized Zone (DMZ), ensuring proper response to such events has been a challenge. Therefore, in order to respond and manage these forest fires appropriately, an improvement in the forest fire predictability through integration of mountain weather information observed at the most optimal site is necessary. This study is a proactive case in which a spatial analysis and an on-site assessment method were developed for selecting an optimum site for a mountain weather observation in national forest. For spatial analysis, the class 1 and 2 forest fire danger areas for the past 10 years, accessibility maximum 100m, Automatic Weather Station (AWS) redundancy within 2.5km, and mountain terrains higher than 200m were analyzed. A final overlay analysis was performed to select the candidates for the field assessment. The sites selected through spatial analysis were quantitatively evaluated based on the optimal meteorological environment, forest and hiking trail accessibility, AWS redundancy, and supply of wireless communication and solar powered electricity. The sites with total score of 70 and higher were accepted as adequate. At the final selected sites, an AMOS was established, and integration of mountain and Korea Meteorological Administration (KMA) weather data improved the forest fire predictability in South Korea by 10%. Given these study results, we expect that establishing an automatic mountain meteorology observation station at the optimal sites in inaccessible area and integrating mountain weather data will improve the predictability of forest fires.

Spatial patterns of large natural fires in Sierra Nevada wilderness areas

USGS Publications Warehouse

Collins, B.M.; Kelly, M.; van Wagtendonk, J.W.; Stephens, S.L.

2007-01-01

The effects of fire on vegetation vary based on the properties and amount of existing biomass (or fuel) in a forest stand, weather conditions, and topography. Identifying controls over the spatial patterning of fire-induced vegetation change, or fire severity, is critical in understanding fire as a landscape scale process. We use gridded estimates of fire severity, derived from Landsat ETM+ imagery, to identify the biotic and abiotic factors contributing to the observed spatial patterns of fire severity in two large natural fires. Regression tree analysis indicates the importance of weather, topography, and vegetation variables in explaining fire severity patterns between the two fires. Relative humidity explained the highest proportion of total sum of squares throughout the Hoover fire (Yosemite National Park, 2001). The lowest fire severity corresponded with increased relative humidity. For the Williams fire (Sequoia/Kings Canyon National Parks, 2003) dominant vegetation type explains the highest proportion of sum of squares. Dominant vegetation was also important in determining fire severity throughout the Hoover fire. In both fires, forest stands that were dominated by lodgepole pine (Pinus contorta) burned at highest severity, while red fir (Abies magnifica) stands corresponded with the lowest fire severities. There was evidence in both fires that lower wind speed corresponded with higher fire severity, although the highest fire severity in the Williams fire occurred during increased wind speed. Additionally, in the vegetation types that were associated with lower severity, burn severity was lowest when the time since last fire was fewer than 11 and 17 years for the Williams and Hoover fires, respectively. Based on the factors and patterns identified, managers can anticipate the effects of management ignited and naturally ignited fires at the forest stand and the landscape levels. ?? 2007 Springer Science+Business Media, Inc.

Fire regime characterization in Mediterranean ecosystems of Southern Italy

NASA Astrophysics Data System (ADS)

Lanorte, A.; Lasaponara, R.

2009-04-01

This paper addresses the wildfire regime in Mediterranean ecosystems of Southern Italy. Fire regimes refer to average fire conditions (including fire size, fire density, fire frequency, fire seasonality, fire intensity, fire severity, fire thresholds, etc.) occurring over a long period of time. Information on spatial pattern of forest fire locations is a key point in the study of the dynamics of fire disturbance, and allows us to improve the knowledge of past and current role of fire. Historical evidence clearly shows what did happen and this can fruitfully help to understand what is happening and what could happen in the next future. Mapping fire regimes is very challenging, because fire ocurrence features are the expression of the interactions between climate, fire, vegetation, topography, social factors. The main objective of this work is to provide a comprehensive characterization of the fire regime in Italy based on a recently updated national wildfire database. Fire data were obtained from the Italian National Forestry Service. This national database is comprised of information contained in individual fire reports completed for every fire that occurs on public lands in the Italian peninsula. Complete data were only available for 1996-2006 at the time we accessed the database, which determined the years we analysed. The primary fire history variables that we reported were number of fires, area burned, burning time and duration, and fire size (average size of individual fires) The wildfire records (wildfire area, location, time, vegetation) were analysed with other environmental (fuel availability and type), topographic features, and meteorological/climatological data. Results of our analysis could help better understand the different factors on the wildfire regime in Mediterranean ecosystems of Southern Italy.

High resolution fire risk mapping in Italy

NASA Astrophysics Data System (ADS)

Fiorucci, Paolo; Biondi, Guido; Campo, Lorenzo; D'Andrea, Mirko

2014-05-01

The high topographic and vegetation heterogeneity makes Italy vulnerable to forest fires both in the summer and in winter. In particular, northern regions are predominantly characterized by a winter fire regime, mainly due to frequent extremely dry winds from the north, while southern and central regions and the large islands are characterized by a severe summer fire regime, because of the higher temperatures and prolonged lack of precipitation. The threat of wildfires in Italy is not confined to wooded areas as they extend to agricultural areas and urban-forest interface areas. The agricultural and rural areas, in the last century, have been gradually abandoned, especially in areas with complex topography. Many of these areas were subject to reforestation, leading to the spread of pioneer species mainly represented by Mediterranean conifer, which are highly vulnerable to fire. Because of the frequent spread of fire, these areas are limited to the early successional stages, consisting mainly of shrub vegetation; its survival in the competition with the climax species being ensured by the spread of fire itself. Due to the frequency of fire ignition — almost entirely man caused — the time between fires on the same area is at least an order of magnitude less than the time that would allow the establishment of forest climax species far less vulnerable to fire. In view of the limited availability of fire risk management resources, most of which are used in the management of national and regional air services, it is necessary to precisely identify the areas most vulnerable to fire risk. The few resources available can thus be used on a yearly basis to mitigate problems in the areas at highest risk by defining a program of forest management interventions, which is expected to make a significant contribution to the problem in a few years' time. The goal of such detailed planning is to dramatically reduce the costs associated with water bombers fleet management and fire extinguishing actions, leaving more resources to improve safety in areas at risk. With the availability of fire perimeters mapped over a period spanning from 5 to 10 years, depending by the region, a procedure was defined in order to assess areas at risk with high spatial resolution (900 m2) based on objective criteria by observing past fire events. The availability of fire perimeters combined with a detailed knowledge of topography and land cover allowed to understand which are the main features involved in forest fire occurrences and their behaviour. The seasonality of the fire regime was also considered, partitioning the analysis in two macro season (November- April and May- October). In addition, the total precipitation obtained from the interpolation of 30 years-long time series from 460 raingauges and the average air temperature obtained downscaling 30 years ERA-INTERIM data series were considered. About 48000 fire perimeters which burnt about 5500 km2 were considered in the analysis. The analysis has been carried out at 30 m spatial resolution. Some important considerations relating to climate and the territorial features that characterize the fire regime at national level contribute to better understand the forest fire phenomena. These results allow to define new strategies for forest fire prevention and management extensible to other geographical areas.

Increased dietary sodium is independently associated with greater mortality among prevalent hemodialysis patients.

PubMed

Mc Causland, Finnian R; Waikar, Sushrut S; Brunelli, Steven M

2012-07-01

Dietary sodium is thought to play a major role in the pathogenesis of hypertension, hypervolemia, and mortality in hemodialysis patients; hence, sodium restriction is almost universally recommended. Since the evidence upon which to base these assumptions is limited, we undertook a post-hoc analysis of 1770 patients in the Hemodialysis Study with available dietary, clinical, and laboratory information. Within this cohort, 772 were men, 1113 black, and 786 diabetic, with a mean age of 58 years and a median dietary sodium intake of 2080 mg/day. After case-mix adjustment, linear regression modeling found that higher dietary sodium was associated with a greater ultrafiltration requirement, caloric and protein intake; sodium to calorie intake ratio was associated with a greater ultrafiltration requirement; and sodium to potassium ratio was associated with higher serum sodium. No indices were associated with the pre-dialysis systolic blood pressure. Cox regression modeling found that higher baseline dietary sodium and the ratio of sodium to calorie or potassium were each independently associated with greater all-cause mortality. No association between a prescribed dietary sodium restriction and mortality were found. Thus, higher reported dietary sodium intake is independently associated with greater mortality among prevalent hemodialysis patients. Randomized trials will be necessary to determine whether dietary sodium restriction improves survival.

Geospatial monitoring and prioritization of forest fire incidences in Andhra Pradesh, India.

PubMed

Manaswini, G; Sudhakar Reddy, C

2015-10-01

Forest fire has been identified as one of the key environmental issue for long-term conservation of biodiversity and has impact on global climate. Spatially multiple observations are necessary for monitoring of forest fires in tropics for understanding conservation efficacy and sustaining biodiversity in protected areas. The present work was carried out to estimate the spatial extent of forest burnt areas and fire frequency using Resourcesat Advanced Wide Field Sensor (AWiFS) data (2009, 2010, 2012, 2013 and 2014) in Andhra Pradesh, India. The spatio-temporal analysis shows that an area of 7514.10 km(2) (29.22% of total forest cover) has been affected by forest fires. Six major forest types are distributed in Andhra Pradesh, i.e. semi-evergreen, moist deciduous, dry deciduous, dry evergreen, thorn and mangroves. Of the total forest burnt area, dry deciduous forests account for >75%. District-wise analysis shows that Kurnool, Prakasam and Cuddapah have shown >100 km(2) of burnt area every year. The total forest burnt area estimate covering protected areas ranges between 6.9 and 22.3% during the study period. Spatial burnt area analysis for protected areas in 2014 indicates 37.2% of fire incidences in the Nagarjunasagar Srisailam Tiger Reserve followed by 20.2 % in the Sri Lankamalleswara Wildlife Sanctuary, 20.1% in the Sri Venkateswara Wildlife Sanctuary and 17.4% in the Gundla Brahmeswaram Wildlife Sanctuary. The analysis of cumulative fire occurrences from 2009 to 2014 has helped in delineation of conservation priority hotspots using a spatial grid cell approach. Conservation priority hotspots I and II are distributed in major parts of study area including protected areas of the Nagarjunasagar Srisailam Tiger Reserve and Gundla Brahmeswaram Wildlife Sanctuary. The spatial database generated will be useful in studies related to influence of fires on species adaptability, ecological damage assessment and conservation planning.

Fire-climate-human interactions during the postglacial period at Sunrise Ridge, Mount Rainier National Park, Washington (USA)

NASA Astrophysics Data System (ADS)

Walsh, Megan K.; Lukens, Michael L.; McCutcheon, Patrick T.; Burtchard, Greg C.

2017-12-01

With the creation of Mount Rainier National Park (MORA) in 1899 came the active management of the park's landscapes and a heavy emphasis on fire suppression. Today, managers at MORA seek to better manage current fire activity; however, this requires an improved understanding of past fire activity on the mountain. In this study high-resolution macroscopic charcoal analysis and pollen analysis of lake sediment records was used to reconstruct the postglacial fire and vegetation history for the Sunrise Ridge area of MORA. Fire activity was lowest during the Late Glacial when vegetation was sparse and climate was cool and dry. Fire activity increased during the early Holocene as the regional climate warmed and dried, and burnable biomass became more abundant. Fire activity continued to increase into the middle Holocene (until ca. 6600 cal yr BP) even as the regional climate became wetter and eventually cooler; the modern-day mesic forest and subalpine meadow landscapes of the park established at this time. Fire activity was generally highest and mean fire return intervals were lowest on Sunrise Ridge during the late Holocene, and are consistent with tree-ring based estimates of fire frequency. The similarity between the Sunrise Ridge and other paleofire records in the Pacific Northwest suggests that broad-scale climatic shifts, such as the retreat of the Cordilleran ice sheet and changes in annual insolation, as well as increased interannual climate variability (i.e., drought) particularly in the middle to late Holocene, were responsible for changes in fire activity during the postglacial period. However, abundant and increasing archaeological evidence from Sunrise Ridge during the middle to late Holocene suggests that humans may have also influenced the landscape at this time. It is likely that fires will continue to increase at MORA as drought becomes a more frequent occurrence in the Pacific Northwest.

Study on the Fire Damage Characteristics of the New Qidaoliang Highway Tunnel: Field Investigation with Computational Fluid Dynamics (CFD) Back Analysis

PubMed Central

Lai, Hongpeng; Wang, Shuyong; Xie, Yongli

2016-01-01

In the New Qidaoliang Tunnel (China), a rear-end collision of two tanker trunks caused a fire. To understand the damage characteristics of the tunnel lining structure, in situ investigation was performed. The results show that the fire in the tunnel induced spallation of tunnel lining concrete covering 856 m3; the length of road surface damage reached 650 m; the sectional area had a maximum 4% increase, and the mechanical and electrical facilities were severely damaged. The maximum area loss happened at the fire spot with maximum observed concrete spallation up to a thickness of 35.4 cm. The strength of vault and side wall concrete near the fire source was significantly reduced. The loss of concrete strength of the side wall near the inner surface of tunnel was larger than that near the surrounding rock. In order to perform back analysis of the effect of thermal load on lining structure, simplified numerical simulation using computational fluid dynamics (CFD) was also performed, repeating the fire scenario. The simulated results showed that from the fire breaking out to the point of becoming steady, the tunnel experienced processes of small-scale warming, swirl around fire, backflow, and longitudinal turbulent flow. The influence range of the tunnel internal temperature on the longitudinal downstream was far greater than on the upstream, while the high temperature upstream and downstream of the transverse fire source mainly centered on the vault or the higher vault waist. The temperature of each part of the tunnel near the fire source had no obvious stratification phenomenon. The temperature of the vault lining upstream and downstream near the fire source was the highest. The numerical simulation is found to be in good agreement with the field observations. PMID:27754455

Study on the Fire Damage Characteristics of the New Qidaoliang Highway Tunnel: Field Investigation with Computational Fluid Dynamics (CFD) Back Analysis.

PubMed

Lai, Hongpeng; Wang, Shuyong; Xie, Yongli

2016-10-15

In the New Qidaoliang Tunnel (China), a rear-end collision of two tanker trunks caused a fire. To understand the damage characteristics of the tunnel lining structure, in situ investigation was performed. The results show that the fire in the tunnel induced spallation of tunnel lining concrete covering 856 m³; the length of road surface damage reached 650 m; the sectional area had a maximum 4% increase, and the mechanical and electrical facilities were severely damaged. The maximum area loss happened at the fire spot with maximum observed concrete spallation up to a thickness of 35.4 cm. The strength of vault and side wall concrete near the fire source was significantly reduced. The loss of concrete strength of the side wall near the inner surface of tunnel was larger than that near the surrounding rock. In order to perform back analysis of the effect of thermal load on lining structure, simplified numerical simulation using computational fluid dynamics (CFD) was also performed, repeating the fire scenario. The simulated results showed that from the fire breaking out to the point of becoming steady, the tunnel experienced processes of small-scale warming, swirl around fire, backflow, and longitudinal turbulent flow. The influence range of the tunnel internal temperature on the longitudinal downstream was far greater than on the upstream, while the high temperature upstream and downstream of the transverse fire source mainly centered on the vault or the higher vault waist. The temperature of each part of the tunnel near the fire source had no obvious stratification phenomenon. The temperature of the vault lining upstream and downstream near the fire source was the highest. The numerical simulation is found to be in good agreement with the field observations.

The analysis of a complex fire event using multispaceborne observations

NASA Astrophysics Data System (ADS)

Andrei, Simona; Carstea, Emil; Marmureanu, Luminita; Ene, Dragos; Binietoglou, Ioannis; Nicolae, Doina; Konsta, Dimitra; Amiridis, Vassilis; Proestakis, Emmanouil

2018-04-01

This study documents a complex fire event that occurred on October 2016, in Middle East belligerent area. Two fire outbreaks were detected by different spacecraft monitoring instruments on board of TERRA, CALIPSO and AURA Earth Observation missions. Link with local weather conditions was examined using ERA Interim Reanalysis and CAMS datasets. The detection of the event by multiple sensors enabled a detailed characterization of fires and the comparison with different observational data.

Fires Readiness: The State of US Army Fires in Support of Combined Arms Maneuver at the Division Level

DTIC Science & Technology

2016-06-10

proficiency in their core competencies. 15. SUBJECT TERMS Fires, Fire Support, DIVARTY, FAB , Combined Arms Maneuver, DOTMLPF 16. SECURITY...FAA Functional Area Analysis FAB Field Artillery Brigade FER Final Exercise Report FFA HQ Force Field Artillery Headquarters FM Field Manual FNA...function. This provided me the opportunity to work with several Division Artillerys (DIVARTYs) and Field Artillery Brigades ( FABs ). During this time

A statistical procedure for fire risk mapping in Italy

NASA Astrophysics Data System (ADS)

Fiorucci, Paolo; Biondi, Guido; Campo, Lorenzo; D'Andrea, Mirko

2015-04-01

The high topographic and vegetation heterogeneity makes Italy vulnerable to forest fires both in the summer and in winter. In particular, northern regions are predominantly characterized by a winter fire regime, mainly due to frequent extremely dry winds from the north, while southern and central regions and the large islands are characterized by a severe summer fire regime, because of the higher temperatures and prolonged lack of precipitation. The threat of wildfires in Italy is not confined to wooded areas as they extend to agricultural areas and urban-forest interface areas. In view of the limited availability of fire risk management resources, most of which are used in the management of national and regional air services, it is necessary to precisely identify the areas most vulnerable to fire risk. The few resources available can thus be used on a yearly basis to mitigate problems in the areas at highest risk by defining a program of forest management interventions, which is expected to make a significant contribution to the problem in a few years' time. Given the availability of fire perimeters mapped over a period spanning from 5 to 10 years, depending by the region, a statistical procedure was defined in order to assess areas at risk based on objective criteria by observing past fire events. The availability of fire perimeters combined with a detailed knowledge of topography and land cover allowed to understand which are the main features involved in forest fire occurrences and their behavior. The seasonality of the fire regime was also considered, partitioning the analysis in two macro season (November-April and May- October). In addition, the total precipitation obtained from the interpolation of 30 years-long time series from 460 raingauges and the average air temperature obtained downscaling 30 years ERA-INTERIM data series were considered. The analysis consists on the subdivision of the territory in classes based on the named information layers (elevation, slope, rainfall height, temperature, etc.) with a recursive algorithm that ensures the equal numerosity of each class. The number of fires occurred in each class is then assessed basing on time series in the last decade, in order to have an estimation of the fire hazard with a contant statistical confidence. The analysis was carried out at a spatial resolution of 500 m on the whole Italian territory by using a dataset of fires occurrences that spans from 2007 to 2013.

Improvement of aqueous solubility and rectal absorption of 6-mercaptopurine by addition of sodium benzoate.

PubMed

Takeichi, Y; Kimura, T

1994-10-01

The solubility of 6-mercaptopurine (6-MP) in water increased as the concentration of sodium benzoate or sodium hippurate in the solution increased. The solubility of 6-MP in 20% (w/v) sodium benzoate or sodium hippurate solution was about 6-fold larger than that of 6-MP alone. The stability constant of the soluble complex of 6-MP with sodium benzoate was estimated to be 2-8 M-1 from (1) phase-solubility study and (2) analysis of chemical shifts observed in 1H-NMR. Partition of 6-MP from the saturated solution to n-octanol was also greatly increased by the addition of sodium benzoate or sodium hippurate, the degree being less in the latter. Administration of 6-MP with 20% (w/v) sodium benzoate to rat rectum resulted in enhanced absorption and the area under the plasma concentration-time curve was comparable to that obtained by intravenous administration (bioavailability = 100%), while the bioavailability after intrarectal administration of 6-MP with 20% (w/v) sodium hippurate was only 9%. The reason for the difference was discussed.

Analysis of zone of vulnurability and impact of forest fires in forest ecosystems in north algeria by susing remote sensing

NASA Astrophysics Data System (ADS)

Zegrar, Ahmed

2010-05-01

The Forest in steppe present ecological diversity, and seen climatic unfavourable conditions in zone and impact of forest fires; we notes deterioration of physical environment particularly, deterioration of natural forest. This deterioration of forests provokes an unbalance of environment witch provokes a process of deterioration advanced in the ultimate stadium is desertification. By elsewhere, where climatic conditions are favourable, the fire is an ecological and acted agent like integral part of evolution of the ecosystems, the specific regeneration of plants are influenced greatly by the regime of fire (season of fire, intensity, interval), witch leads to the recuperation of the vegetation of meadow- fire. In this survey we used the pictures ALSAT-1 for detection of zones with risk of forest fire and their impact on the naturals forests in region named TLEMCEN in the north west of Algeria. A thematic detailed analysis of forests well attended ecosystems some processing on the picture ALSAT-1, we allowed to identify and classifying the forests in there opinion components flowers. We identified ampleness of fire on this zone also. Some parameters as the slope, the proximity to the road and the forests formations were studied in the goal of determining the zones to risk of forest fire. A crossing of diaper of information in a GIS according to a very determined logic allowed classifying the zones in degree of risk of fire in semi arid zone witch forest zone not encouraging the regeneration but permitting the installation of cash of steppe which encourages the desertification.

Forest fires impact in semi arid lands in Algeria, analysis and followed of desertification by using remote sensing and GIS

NASA Astrophysics Data System (ADS)

Zegrar, Ahmed

The Forest in steppe present ecological diversity, and seen climatic unfavourable conditions in zone and impact of forest fires; we notes deterioration of physical environment particularly, deterioration of natural forest. This deterioration of forests provokes an unbalance of environment witch provokes a process of deterioration advanced in the ultimate stadium is desertification. By elsewhere, where climatic conditions are favourable, the fire is an ecological and acted agent like integral part of evolution of the ecosystems, the specific regeneration of plants are influenced greatly by the regime of fire (season of fire, intensity, interval), who leads to the recuperation of the vegetation of meadow- fire. In this survey we used the pictures ALSAT-1 for detection of zones with risk of forest fire and their impact on the naturals forests in region of Tlemcen. A thematic detailed analysis of forests well attended ecosystems some processing on the picture ALSAT-1, we allowed to identify and classifying the forests in there opinion components flowers. we identified ampleness of fire on this zone also. Some parameters as the slope, the proximity to the road and the forests formations were studied in the goal of determining the zones to risk of forest fire. A crossing of diaper of information in a SIG according to a very determined logic allowed to classify the zones in degree of risk of fire in a middle arid in a forest zone not encouraging the regeneration on the other hand permitting the installation of cash of steppe which encourages the desertification.

Understanding the Factors that Influence Perceptions of Post-Wildfire Landscape Recovery Across 25 Wildfires in the Northwestern United States.

PubMed

Kooistra, C; Hall, T E; Paveglio, T; Pickering, M

2018-01-01

Disturbances such as wildfire are important features of forested landscapes. The trajectory of changes following wildfires (often referred to as landscape recovery) continues to be an important research topic among ecologists and wildfire scientists. However, the landscape recovery process also has important social dimensions that may or may not correspond to ecological or biophysical perspectives. Perceptions of landscape recovery may affect people's attitudes and behaviors related to forest and wildfire management. We explored the variables that influence people's perceptions of landscape recovery across 25 fires that occurred in 2011 or 2012 in the United States of Washington, Oregon, Idaho, and Montana and that represented a range of fire behavior characteristics and landscape impacts. Residents near each of the 25 fires were randomly selected to receive questionnaires about their experiences with the nearby fire, including perceived impacts and how the landscape had recovered since the fire. People generally perceived landscapes as recovering, even though only one to two years had passed. Regression analysis suggested that perceptions of landscape recovery were positively related to stronger beliefs about the ecological role of fire and negatively related to loss of landscape attachment, concern about erosion, increasing distance from the fire perimeter, and longer lasting fires. Hierarchical linear modeling (HLM) analysis indicated that the above relationships were largely consistent across fires. These findings highlight that perceptions of post-fire landscape recovery are influenced by more than vegetation changes and include emotional and cognitive factors. We discuss the management implications of these findings.

Fires in P-3 Aircraft Oxygen Systems

NASA Technical Reports Server (NTRS)

Stoltzfus, Joel

2006-01-01

Fires in three P3 aircraft oxygen systems have occurred: one in the Royal Australian Air Force (RAAF) in 1984 and two in the U.S. Navy in 1998 and 2003. All three fires started in the aluminum manifold and check valve (MCV) assembly and produced similar damages to the aircraft in which they occurred. This paper discusses a failure analysis conducted by the NASA Johnson Space Center White Sands Test Facility (WSTF) Oxygen Hazards and Testing Team on the 2003 U.S. Navy VP62 fire. It was surmised that the fire started due to heat generated by an oxygen leak past a silicone check valve seal or possibly because of particle impact near the seat of one of the MCV assembly check valves. An additional analysis of fires in several check valve poppet seals from other aircraft is discussed. These burned poppet seals came from P3 oxygen systems that had been serviced at the Naval Air Station (NAS) in Jacksonville following standard fill procedures. It was concluded that these seal fires occurred due to the heat from compression heating, particle impact, or the heat generated by an oxygen leak past the silicone check valve seal. The fact that catastrophic fires did not occur in the case of each check valve seal fire was attributed to the protective nature of the aluminum oxide layer on the check valve poppets. To prevent future fires of this nature, the U.S. and Canadian fleets of P3 aircraft have been retrofitted with MCV assemblies with an upgraded design and more burn-resistant materials.

Understanding the Factors that Influence Perceptions of Post-Wildfire Landscape Recovery Across 25 Wildfires in the Northwestern United States

NASA Astrophysics Data System (ADS)

Kooistra, C.; Hall, T. E.; Paveglio, T.; Pickering, M.

2018-01-01

Disturbances such as wildfire are important features of forested landscapes. The trajectory of changes following wildfires (often referred to as landscape recovery) continues to be an important research topic among ecologists and wildfire scientists. However, the landscape recovery process also has important social dimensions that may or may not correspond to ecological or biophysical perspectives. Perceptions of landscape recovery may affect people's attitudes and behaviors related to forest and wildfire management. We explored the variables that influence people's perceptions of landscape recovery across 25 fires that occurred in 2011 or 2012 in the United States of Washington, Oregon, Idaho, and Montana and that represented a range of fire behavior characteristics and landscape impacts. Residents near each of the 25 fires were randomly selected to receive questionnaires about their experiences with the nearby fire, including perceived impacts and how the landscape had recovered since the fire. People generally perceived landscapes as recovering, even though only one to two years had passed. Regression analysis suggested that perceptions of landscape recovery were positively related to stronger beliefs about the ecological role of fire and negatively related to loss of landscape attachment, concern about erosion, increasing distance from the fire perimeter, and longer lasting fires. Hierarchical linear modeling (HLM) analysis indicated that the above relationships were largely consistent across fires. These findings highlight that perceptions of post-fire landscape recovery are influenced by more than vegetation changes and include emotional and cognitive factors. We discuss the management implications of these findings.

Assessment of sodium status in large ruminants by measuring the sodium-to-potassium ratio in muzzle secretions.

PubMed

Singh, S P; Rani, D

1999-09-01

To develop a simple diagnostic test to assess sodium status in large ruminants on the basis of the sodium-to-potassium ratio (Na:K) and to determine its relevance. 7 buffalo heifers and 21 lactating, pregnant, and nonpregnant dairy cows and heifers. Buffalo heifers were subjected in 2 experiments to variable dietary sodium intake or sodium depletion and changes in sodium and potassium concentrations; Na:K was simultaneously monitored in various body fluids to study its value for indicating sodium status. Validity of the muzzle secretion test was assessed. Muzzle secretion and urinary Na:K and sodium concentration, but not serum electrolyte concentrations, reflected the sodium status of buffalo heifers in response to the widely variable intake of sodium (0.03 to 0.16% of dry matter [DM]). Progressive sodium depletion during an 11-day period, using saliva deprivation caused reciprocal changes in sodium and potassium concentrations in saliva and muzzle secretion, but not in urine. Decreasing urine sodium concentration was associated with decreasing urine potassium concentration. Saliva, urine, and muzzle secretion Na:K closely reflected the degree of sodium deficit. Buffaloes or dairy cows maintained on optimal sodium intake had muzzle secretion and urine Na:K > 0.30. Muzzle secretion or urine Na:K < 0.20 or < 0.10, respectively, was indicative of sodium deficiency. Analysis of muzzle secretion Na:K, and to a large extent urine Na:K, may be used as a convenient diagnostic tool to assess sodium status in large ruminants. It has accuracy similar to that of saliva Na:K.

Consumer awareness of salt and sodium reduction and sodium labeling.

PubMed

Kim, M K; Lopetcharat, K; Gerard, P D; Drake, M A

2012-09-01

Reduction of dietary sodium by reduction of sodium in foods is a current industry target. Quantitative information on consumer knowledge of sodium and reduction of dietary sodium is limited. The objectives of this study were to characterize consumer knowledge and awareness of sodium and salt reduction in foods. Consumers (n = 489) participated in a quantitative internet survey designed to gather knowledge and attitudes towards dietary sodium, sodium in foods, and health. Eating habits and food consumption characteristics, knowledge of salt and sodium, and interest in health and wellness were probed. Saltiness believe and sodium knowledge indices were calculated based on correct responses to salt levels in food products. Kano analysis was conducted to determine the role of nutrition labels and satisfaction/dissatisfaction of foods. Consumers were aware of the presence of sodium in "salty" foods, and that sodium was part of salt. People who had a family history of certain diseases associated with a higher intake of dietary sodium did not necessarily have more knowledge of the relationship between sodium intake and a specific disease compared to consumers with no family history. Sodium content on the food label panel did not influence consumer dissatisfaction; however, sodium content did not necessarily increase consumer product satisfaction either. The addition of a healthy nutrient (that is, whole grain, fiber) into a current food product was appealing to consumers. For nutrient labeling, a "reduced" claim was more appealing to consumers than a "free" claim for "unhealthy" nutrients such as fat, sodium, and sugar. This study demonstrated the current state of consumer knowledge on sodium and salt reduction, and consumer perception of the relationship between diets high in sodium and many chronic diseases. Information that may contribute to consumer satisfaction on nutrition panel labeling was also determined. © 2012 Institute of Food Technologists®

The in vitro antibiotic release from anti-washout apatite cement using chitosan.

PubMed

Takechi, Masaaki; Miyamoto, Youji; Momota, Yukihiro; Yuasa, Tetsuya; Tatehara, Seikou; Nagayama, Masaru; Ishikawa, Kunio; Suzuki, Kazuomi

2002-10-01

The in vitro antibiotic release from anti-washout apatite cement using chitosan (aw-AC(chi)) was investigated in a preliminary evaluation. Flomoxef sodium was employed as the antibiotic and was incorporated into the powder phase aw-AC(chi) at up to 10%. The setting times were measured for aw-AC(chi) containing various amounts of flomoxef sodium. X-ray diffraction (XRD) analysis was also conducted for the identification of products. To evaluate the drug release profile, set aw-AC was immersed in saline and the released flomoxef sodium was determined at regular intervals. The setting time was prolonged slightly with the addition of flomoxef sodium. The difference at 10% flomoxef sodium (0% vs. 10%) was not significant (p>0.05), and can be negligible in clinic. The XRD analysis revealed that formation of hydroxyapatite (HAP) from aw-AC(chi) was reduced, even after 24 h, when the aw-AC(chi) contained flomoxef sodium at 8% or more. The flomoxef sodium release from aw-AC(chi) showed the typical profile observed in skeleton type drug delivery system (DDS). Changing the concentration of chitosan can control the rate of drug release from aw-AC. Therefore, we conclude that aw-AC(chi) is a good candidate for potential use as a DDS carrier that may be useful in surgical operations.

Analysis of Architectural Building Design Influences on Fire Spread in Densely Urban Settlement using Cellular Automata

NASA Astrophysics Data System (ADS)

Tambunan, L.; Salamah, H.; Asriana, N.

2017-03-01

This study aims to determine the influence of architectural design on the risk of fire spread in densely urban settlement area. Cellular Automata (CA) is used to analyse the fire spread pattern, speed, and the extent of damage. Four cells represent buildings, streets, and fields characteristic in the simulated area, as well as their flammability level and fire spread capabilities. Two fire scenarios are used to model the spread of fire: (1) fire origin in a building with concrete and wood material majority, and (2) fire origin in building with wood material majority. Building shape, building distance, road width, and total area of wall openings are considered constant, while wind is ignored. The result shows that fire spread faster in the building area with wood majority than with concrete majority. Significant amount of combustible building material, absence of distance between buildings, narrow streets and limited fields are factors which influence fire spread speed and pattern as well as extent of damage when fire occurs in the densely urban settlement area.

FireStem2D – A Two-Dimensional Heat Transfer Model for Simulating Tree Stem Injury in Fires

PubMed Central

Chatziefstratiou, Efthalia K.; Bohrer, Gil; Bova, Anthony S.; Subramanian, Ravishankar; Frasson, Renato P. M.; Scherzer, Amy; Butler, Bret W.; Dickinson, Matthew B.

2013-01-01

FireStem2D, a software tool for predicting tree stem heating and injury in forest fires, is a physically-based, two-dimensional model of stem thermodynamics that results from heating at the bark surface. It builds on an earlier one-dimensional model (FireStem) and provides improved capabilities for predicting fire-induced mortality and injury before a fire occurs by resolving stem moisture loss, temperatures through the stem, degree of bark charring, and necrotic depth around the stem. We present the results of numerical parameterization and model evaluation experiments for FireStem2D that simulate laboratory stem-heating experiments of 52 tree sections from 25 trees. We also conducted a set of virtual sensitivity analysis experiments to test the effects of unevenness of heating around the stem and with aboveground height using data from two studies: a low-intensity surface fire and a more intense crown fire. The model allows for improved understanding and prediction of the effects of wildland fire on injury and mortality of trees of different species and sizes. PMID:23894599

Usage of "Powergraph" software at laboratory lessons of "general physics" department of MEPhI

NASA Astrophysics Data System (ADS)

Klyachin, N. A.; Matronchik, A. Yu.; Khangulyan, E. V.

2017-01-01

One considers usage of "PowerGraph" software in laboratory exercise "Study of sodium spectrum" of physical experiment lessons. Togethe with the design of experiment setup, one discusses the sodium spectra digitized with computer audio chip. Usage of "PowerGraph" software in laboratory experiment "Study of sodium spectrum" allows an efficient visualization of the sodium spectrum and analysis of its fine structure. In particular, it allows quantitative measurements of the wavelengths and line relative intensities.

Storage Reliability of Missile Materiel Program. Storage Reliability Analysis Summary Report. Volume 1. Electrical and Electronic Devices

DTIC Science & Technology

1976-05-01

since the platinum silicide and titanium metals also offer very low mobility to the alkaline ions, the BLSJ . is inert to sodium . Inversion and...gettering agents for sodium ions, thus making the cont&-nination far less mobile. The stability of the structural and electrical properties of the oxide...to be an effective barrier to sodium migration. In Beam Lead Sealed ,unction (BLSJ) devices, the silicon nitride seals the devices from sodium and

Active Range Restoration via Caustic Hydrolysis of Explosively Contaminated Metal Parts

DTIC Science & Technology

2011-05-12

Ammonia, Formate – Sodium Cyanide  Low concentration (40 ppm)  Well established mitigation options • Primary Comp B off-gas components: – Ammonia, NOx...neutralized • In situ sodium cyanide treatment (D/H Reactor) – Hydrogen peroxide (H2O2) oxidizes CN- to CNO- • Analysis of liquid sample for sodium ... cyanide • pH neutralization and hydrolysate thickening – Phosphoric acid (H3PO4) forms buffer – Resulting sodium phosphate thickens to paste Lower

Sodium Analysis in Whole Blood of Athletes Using NAA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kovacs, Luciana; Zamboni, Cibele B.; Nunes, Lazaro A. S.

In this investigation the sodium levels in blood were analyzed in athletes submitted to constant load exercise at treadmill (LABEX and UNICAMP) by NAA. These data were compared with the rest condition (before starting the exercise program) as well as with the sodium levels of the healthy group (control group) select from Blood Banks. The results showed alterations in sodium levels of the athletes during the exercise training, mainly increase, suggesting the necessity of its evaluation during physical activities.