Sample records for sole source justifications

  1. 77 FR 35624 - Federal Acquisition Regulation; Justification and Approval of Sole-Source 8(a) Contracts: Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-14

    ... 2] RIN 9000-AL55 Federal Acquisition Regulation; Justification and Approval of Sole-Source 8(a... removes language indicating that the applicable section of the National Defense Authorization Act for...: June 8, 2012. Laura Auletta, Director, Office of Governmentwide Acquisition Policy, Office of...

  2. 75 FR 53269 - Federal Acquisition Regulation; Tribal Consultation; Justification and Approval of Sole-Source 8...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... Administration (NASA). ACTION: Notice of tribal consultation and outreach meetings and request for comments... owned by Indian Tribes and Alaska Native Corporations, if the sole-source award is to exceed $20 million... Indian Tribes and Alaska Native Corporations. As explained in E.O. 13175, Tribal consultation is a...

  3. 48 CFR 1513.170-1 - Contents of sole source justifications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the micro-purchase threshold. The statement must cite one or more of the circumstances in FAR 6.302 and the necessary facts to support each circumstance. Although program offices may not cite the...

  4. 77 FR 23369 - Federal Acquisition Regulation; Justification and Approval of Sole-Source 8(a) Contracts

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ... DEPARTMENT OF DEFENSE GENERAL SERVICES ADMINISTRATION NATIONAL AERONAUTICS AND SPACE... AGENCY: Department of Defense (DoD), General Services Administration (GSA), and National Aeronautics and... Department of Defense, the General Services Administration, and the National Aeronautics and Space...

  5. 41 CFR 101-26.105 - Justification to support negotiated procurement by GSA for other agencies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... without providing for full and open competition, the agency submitting the requisition will be so notified... without providing for full and open competition (e.g., sole source acquisition), sufficient information... applicable law, if any, authorizing other than full and open competition (see FAR 6.302 (48 CFR 6.302); and...

  6. 41 CFR 101-26.105 - Justification to support negotiated procurement by GSA for other agencies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... without providing for full and open competition, the agency submitting the requisition will be so notified... without providing for full and open competition (e.g., sole source acquisition), sufficient information... applicable law, if any, authorizing other than full and open competition (see FAR 6.302 (48 CFR 6.302); and...

  7. 41 CFR 101-26.105 - Justification to support negotiated procurement by GSA for other agencies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... without providing for full and open competition, the agency submitting the requisition will be so notified... without providing for full and open competition (e.g., sole source acquisition), sufficient information... applicable law, if any, authorizing other than full and open competition (see FAR 6.302 (48 CFR 6.302); and...

  8. 41 CFR 101-26.105 - Justification to support negotiated procurement by GSA for other agencies.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... without providing for full and open competition, the agency submitting the requisition will be so notified... without providing for full and open competition (e.g., sole source acquisition), sufficient information... applicable law, if any, authorizing other than full and open competition (see FAR 6.302 (48 CFR 6.302); and...

  9. 41 CFR 101-26.105 - Justification to support negotiated procurement by GSA for other agencies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... without providing for full and open competition, the agency submitting the requisition will be so notified... without providing for full and open competition (e.g., sole source acquisition), sufficient information... applicable law, if any, authorizing other than full and open competition (see FAR 6.302 (48 CFR 6.302); and...

  10. 78 FR 60875 - Assistant Secretary for Preparedness and Response; Notification of a Sole Source Cooperative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... in Children After Hurricane Katrina. Disaster Medicine and Public Health Preparedness 4(S1): S17-27... in response to emergencies. Justification The Institute of Medicine (IOM) is a nonprofit organization... Framework. Disaster Medicine and Public Health Preparedness 4(S1): S46-S54. \\ii\\ Burkle, F. M. 2011. The...

  11. 76 FR 14559 - Federal Acquisition Regulation; Justification and Approval of Sole-Source 8(a) Contracts

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... Space Administration (NASA). ACTION: Interim rule. SUMMARY: DoD, GSA, and NASA are issuing an interim..., and NASA are issuing an interim rule amending the FAR, to implement section 811 of the National... meetings, DoD, GSA, and NASA weighed the costs and benefits of publishing this rule as proposed or interim...

  12. Undergraduate Students' Justifications for Source Selection in a Digital Academic Context

    ERIC Educational Resources Information Center

    List, Alexandra; Grossnickle, Emily M.; Alexander, Patricia A.

    2016-01-01

    To complete any academic tasks using information from the Internet, undergraduate students first have to select the appropriate sources. However, the types of justifications that undergraduates provide for source selection and how these justifications may be impacted by task characteristics have been underexamined. This study explored…

  13. Know versus Familiar: Differentiating states of awareness in others' subjective reports of recognition.

    PubMed

    Williams, Helen L; Moulin, Chris J A

    2015-01-01

    In the Remember-Know paradigm whether a Know response is defined as a high-confidence state of certainty or a low-confidence state based on familiarity varies across researchers and can influence participants' responses. The current experiment was designed to explore differences between the states of Know and Familiar. Participants studied others' justification statements to "Know" recognition decisions and separated them into two types. Crucially, participants were not provided definitions of Know and Familiar on which to sort the items--their judgements were based solely on the phenomenology described in the justifications. Participants' sorting decisions were shown to reliably map onto expert classification of Know and Familiar. Post-task questionnaire responses demonstrated that both the level of memory detail and confidence expressed in the justifications were central to how participants categorised the items. In sum, given no instructions to do so, participants classify Familiar and Know according to two dimensions: confidence and amount of information retrieved.

  14. Graduate Education in the Humanities: The Need for Reaffirmation, Connection, and Justification. An Occasional Paper.

    ERIC Educational Resources Information Center

    Pellegrino, Edmund D.

    A human society that aspires to more than survival must search continuously for new knowledge; we are all the beneficiaries of the scholar's insatiable desire to know. Graduate study must be nurtured, and cannot ever be the sole preoccupation of academe. Today the crucial balance of things and humans is threatened by the erosion of support for and…

  15. Application of ozone to eliminate tertiary treatment of wastewater used for industrial cooling

    NASA Astrophysics Data System (ADS)

    Merrill, D. T.; Parker, D. S.

    1982-02-01

    The beneficial performance of ozone (biofouling, corrosion, and chemical scaling control), when used as the sole source of cooling water treatment for air conditioning systems, could be obtained at higher cooling water temperatures typical of industrial cooling with secondary municipal effluent (SME) used as the cooling medium was investigated. A pilot cooling system was constructed and a 6 month experimental study initiated to determine process limits, mechanisms of scaling inhibition by ozone, and to evaluate factors influencing technical/economic feasibility. It was found that, while ozone use adequately controlled corrosion and biofouling, chemical scaling could not be prevented at conditions necessary for significant economic justification. Calculations indicate that the makeup waters (SME) used will become saturated with respect to calcium phosphate at less than 2 cycles of concentration, hence, a scaling potential exists at conditions less stringent than those used in the present study.

  16. 77 FR 12930 - Federal Acquisition Regulation: Socioeconomic Program Parity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... on May 6, 2011, reinstating the Rule of Two. C. Sole Source Dollar Thresholds Vary Among the... all socioeconomic programs had the same sole source dollar threshold. Response: The sole source dollar... business socioeconomic contracting program to utilize. D. Sole Source Authority Under the SDVOSB Program...

  17. EPA Region 1 Sole Source Aquifers

    EPA Pesticide Factsheets

    This coverage contains boundaries of EPA-approved sole source aquifers. Sole source aquifers are defined as an aquifer designated as the sole or principal source of drinking water for a given aquifer service area; that is, an aquifer which is needed to supply 50% or more of the drinking water for the area and for which there are no reasonable alternative sources should the aquifer become contaminated.The aquifers were defined by a EPA hydrogeologist. Aquifer boundaries were then drafted by EPA onto 1:24000 USGS quadrangles. For the coastal sole source aquifers the shoreline as it appeared on the quadrangle was used as a boundary. Delineated boundaries were then digitized into ARC/INFO.

  18. A Moral Foundation for Anti-Doping: How Far Have We Progressed? Where Are the Limits?

    PubMed

    Murray, Thomas H

    2017-01-01

    Clarity about the ethical justification of anti-doping is essential. In its absence, critics multiply and confusion abounds. Three broad reasons are typically offered in anti-doping's defense: to protect athletes' health; to promote fairness; and to preserve meaning and values in sport - what the World Anti-Doping Agency (WADA) Code refers to as the spirit of sport. Protecting health is itself an important value, but many sports encourage athletes to take significant risks. The case against doping is buttressed by concern for athletes' health, but it cannot be the sole foundation. Promoting fairness is vital in all sports as the metaphor of the level playing field attests. But playing fields can be leveled by providing performance-enhancing drugs to all competitors. When doping is prohibited, fairness is aided by effective anti-doping. But the fundamental justification for anti-doping is found in the meanings and values we pursue in and through sport. © 2017 S. Karger AG, Basel.

  19. Sole Source Aquifers for NY and NJ

    EPA Pesticide Factsheets

    This layer is the designated sole source aquifers of New York and New Jersey. A Sole Source Aquifer, is an aquifer that supplies 50% or more of the drinking water for a given area where there are no reasonably available alternative sources should the aquifer become contaminated.

  20. 21 CFR 558.62 - Arsanilic acid.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... efficiency; improving pigmentation Withdraw 5 days before slaughter; as sole source of organic arsenic 015565... pigmentation. As erythromycin thiocyanate; withdraw 5 days before slaughter; as sole source of organic arsenic... pigmentation As erythromycin thiocyanate; withdraw 5 days before slaughter; as sole source of organic arsenic...

  1. 21 CFR 520.2088 - Roxarsone tablets.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... period. Withdraw 5 days before slaughter. Use as sole source of organic arsenic. (ii) Growing chickens—(a.... Withdraw 5 days before slaughter. Use as sole source of organic arsenic. (b)(1) Specifications. Each tablet... slaughter. Use as sole source of organic arsenic. (ii) [Reserved] (c)(1) Specifications. Each tablet...

  2. 75 FR 38687 - Federal Acquisition Regulation; FAR Case 2008-023, Clarification of Criteria for Sole Source...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... a sole source SDVOSB concern acquisition. The final rule contains language that more closely mirrors...-AL29 Federal Acquisition Regulation; FAR Case 2008-023, Clarification of Criteria for Sole Source...: Final rule. SUMMARY: The Civilian Agency Acquisition Council and the Defense Acquisition Regulations...

  3. 78 FR 54652 - Sole Source Cooperative Agreement Award to the Association for State and Territorial Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Sole Source Cooperative Agreement Award to the Association...: Notification of a Sole Source Cooperative Agreement Award to the Association for State and Territorial Health... management systems. One of the overarching goals of both the National Health Security Strategy (2009) and the...

  4. 78 FR 54651 - Sole Source Cooperative Agreement Award to the National Association of County and City Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Sole Source Cooperative Agreement Award to the National...: Notification of a Sole Source Cooperative Agreement Award to the National Association of County and City Health... resilience, and strengthen health care, public health, and emergency management systems. One of the...

  5. Appropriate Use Criteria for Echocardiography: Evolving Applications in the Era of Value-Based Healthcare

    PubMed Central

    Singh, Amita

    2017-01-01

    The current climate in healthcare is increasingly emphasizing a value-based approach to diagnostic testing. Cardiac imaging, including echocardiography, has been a primary target of ongoing reforms in healthcare delivery and reimbursement. The Appropriate Use Criteria (AUC) for echocardiography is a physician-derived tool intended to guide utilization in optimal patient care. To date, the AUC have primarily been employed solely as justification for reimbursement, though evolving broader applications to guide clinical decision-making suggest a far more valuable role in the delivery of high-quality and high-value healthcare. PMID:27553788

  6. Defense Logistics Agency Did Not Obtain Fair and Reasonable Prices From Meggitt Aircraft Braking Systems for Sole-Source Commercial Spare Parts (REDACTED)

    DTIC Science & Technology

    2015-05-08

    Defense Logistics Agency Did Not Obtain Fair and Reasonable Prices From Meggitt Aircraft Braking Systems for Sole-Source Commercial Spare Parts...Defense Logistics Agency Did Not Obtain Fair and Reasonable Prices From Meggitt Aircraft Braking Systems for Sole-Source Commercial Spare Parts...D000AH-0180.000) │ i Results in Brief Defense Logistics Agency Did Not Obtain Fair and Reasonable Prices From Meggitt Aircraft Braking Systems for

  7. 48 CFR 8.405-6 - Limited sources justification and approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Limited sources... and belief. (x) Evidence that any supporting data that is the responsibility of technical or... ordering activity contracting officer's knowledge and belief will serve as approval, unless a higher...

  8. 21 CFR 520.2240b - Sulfaethoxypyridazine tablets.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...; do not treat within 16 days of slaughter; as sole source of sulfonamide; milk that has been taken... sole source of sulfonamide; not for use in lactating dairy cows; Federal law restricts this drug to use...

  9. 48 CFR 5.301 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-source justification (excluding brand name) in accordance with 8.405-6; or (ii) Task or delivery orders... Innovation Development Act of 1982 (Pub. L. 97-219); (3) The contract action is an order placed under subpart... one source is available; (6) The contract action— (i) Is for an amount not greater than the simplified...

  10. 21 CFR 520.2087 - Roxarsone soluble powder.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... throughout growing period. Withdraw 5 days before slaughter. Use as sole source of organic arsenic. (2) Swine.... Use as sole source of organic arsenic. [46 FR 41039, Aug. 14, 1981, as amended at 55 FR 8460, Mar. 8...

  11. 78 FR 19261 - Safe Drinking Water Act Sole Source Aquifer Program; Designation of Bainbridge Island, Washington...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... aquifer (U.S. EPA, 1987, Sole Source Aquifer Designation Decision Process, Petition Review Guidance... the petition; U.S. Geological Survey, 2011, Conceptual Model and Numerical Simulation of the...

  12. 21 CFR 520.2087 - Roxarsone soluble powder.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... throughout growing period. Withdraw 5 days before slaughter. Use as sole source of organic arsenic. (2) Swine.... Use as sole source of organic arsenic. [46 FR 41039, Aug. 14, 1981, as amended at 55 FR 8460, Mar. 8...

  13. Light intensity and quality from sole-source light-emitting diodes impact growth, morphology, and nutrient content of Brassica microgreens

    USDA-ARS?s Scientific Manuscript database

    Multi-layer vertical production systems using sole-source (SS) lighting can be used for microgreen production; however, traditional SS lighting can consume large amounts of electrical energy. Light-emitting diodes (LEDs) offer many advantages over conventional light sources including: high photoelec...

  14. Biodegradation of Nitriles in Shale Oil

    PubMed Central

    Aislabie, Jackie; Atlas, Ronald M.

    1988-01-01

    Enrichment cultures were obtained, after prolonged incubation on a shale oil as the sole source of nitrogen, that selectively degraded nitriles. Capillary gas chromatographic analyses showed that the mixed microbial populations in the enrichments degraded the homologous series of aliphatic nitriles but not the aliphatic hydrocarbons, aromatic hydrocarbons, or heterocyclic-nitrogen compounds found in this oil. Time course studies showed that lighter nitriles were removed more rapidly than higher-molecular-weight nitriles. A Pseudomonas fluorescens strain isolated from an enrichment, which was able to completely utilize the individual nitriles undecyl cyanide and undecanenitrile as sole sources of carbon and nitrogen, was unable to attack stearonitrile when provided alone as the growth substrate. A P. aeruginosa strain, also isolated from one of the enrichments, used nitriles but not aliphatic or aromatic hydrocarbons when the oil was used as a sole nitrogen source. However, when the shale oil was used as the sole source of carbon, aliphatic hydrocarbons in addition to nitriles were degraded but aromatic hydrocarbons were still not attacked by this P. aeruginosa strain. PMID:16347731

  15. 12 CFR 701.32 - Payment on shares by public units and nonmembers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... needs, sources and intended uses of public unit and nonmember shares; (ii) Provision for matching maturities of public unit and nonmember shares with corresponding assets, or justification for any mismatch...

  16. 12 CFR 701.32 - Payment on shares by public units and nonmembers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... needs, sources and intended uses of public unit and nonmember shares; (ii) Provision for matching maturities of public unit and nonmember shares with corresponding assets, or justification for any mismatch...

  17. Alternate Sources for Propellant Ingredients.

    DTIC Science & Technology

    1976-07-07

    0dJ variety of reasons; (3) sole source; (4) medical/ OSHA /EPA problems; (5) dependent on foreign Imports; and (6) specification problems. •’. .’ . . I...problems exist for a variety of reasons; (3) sole sourc:e; (4) medical/ OSHA /EPA problems; (5) dependent on foreign imports; and (6) specification problems...regulations of OSHA or EPA affect pro- duction or use of the product; 5. Plant capacity - when demand increases faster that; predictions; 6. Supply

  18. Students Working with Multiple Conflicting Documents on a Scientific Issue: Relations between Epistemic Cognition while Reading and Sourcing and Argumentation in Essays

    ERIC Educational Resources Information Center

    Bråten, Ivar; Ferguson, Leila E.; Strømsø, Helge I.; Anmarkrud, Øistein

    2014-01-01

    Background: There is burgeoning research within educational psychology on both epistemic cognition and multiple-documents literacy, as well as on relationships between the two constructs. Aim: To examine relationships between epistemic cognition concerning the justification of knowledge claims and sourcing and argumentation skills. Sample:…

  19. Using Machine-Learning and Visualisation to Facilitate Learner Interpretation of Source Material

    ERIC Educational Resources Information Center

    Wolff, Annika; Mulholland, Paul; Zdrahal, Zdenek

    2014-01-01

    This paper describes an approach for supporting inquiry learning from source materials, realised and tested through a tool-kit. The approach is optimised for tasks that require a student to make interpretations across sets of resources, where opinions and justifications may be hard to articulate. We adopt a dialogue-based approach to learning…

  20. 48 CFR 19.1406 - Sole source awards to service-disabled veteran-owned small business concerns.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... service-disabled veteran-owned small business concerns. 19.1406 Section 19.1406 Federal Acquisition...-Disabled Veteran-Owned Small Business Procurement Program 19.1406 Sole source awards to service-disabled...-disabled veteran-owned small business concerns; (2) The anticipated award price of the contract, including...

  1. 48 CFR 19.1406 - Sole source awards to service-disabled veteran-owned small business concerns.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... service-disabled veteran-owned small business concerns. 19.1406 Section 19.1406 Federal Acquisition...-Disabled Veteran-Owned Small Business Procurement Program 19.1406 Sole source awards to service-disabled...-disabled veteran-owned small business concerns; (2) The anticipated award price of the contract, including...

  2. 48 CFR 19.1406 - Sole source awards to service-disabled veteran-owned small business concerns.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... service-disabled veteran-owned small business concerns. 19.1406 Section 19.1406 Federal Acquisition...-Disabled Veteran-Owned Small Business Procurement Program 19.1406 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to service-disabled...

  3. 48 CFR 18.116 - Service-disabled Veteran-owned Small Business (SDVOSB) sole source awards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Service-disabled Veteran... Available Acquisition Flexibilities 18.116 Service-disabled Veteran-owned Small Business (SDVOSB) sole source awards. Contracts may be awarded to Service-disabled Veteran-owned Small Business (SDVOSB...

  4. 48 CFR 819.7008 - Sole source awards to veteran-owned small business concerns.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Sole source awards to veteran-owned small business concerns. 819.7008 Section 819.7008 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Service-Disabled Veteran-Owned...

  5. 48 CFR 19.1406 - Sole source awards to service-disabled veteran-owned small business concerns.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... service-disabled veteran-owned small business concerns. 19.1406 Section 19.1406 Federal Acquisition...-Disabled Veteran-Owned Small Business Procurement Program 19.1406 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to service-disabled...

  6. 48 CFR 18.116 - Service-disabled Veteran-owned Small Business (SDVOSB) sole source awards.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Service-disabled Veteran... Available Acquisition Flexibilities 18.116 Service-disabled Veteran-owned Small Business (SDVOSB) sole source awards. Contracts may be awarded to Service-disabled Veteran-owned Small Business (SDVOSB...

  7. 48 CFR 18.116 - Service-disabled Veteran-owned Small Business (SDVOSB) sole source awards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Service-disabled Veteran... Available Acquisition Flexibilities 18.116 Service-disabled Veteran-owned Small Business (SDVOSB) sole source awards. Contracts may be awarded to Service-disabled Veteran-owned Small Business (SDVOSB...

  8. 48 CFR 819.7008 - Sole source awards to veteran-owned small business concerns.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Sole source awards to veteran-owned small business concerns. 819.7008 Section 819.7008 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Service-Disabled Veteran-Owned...

  9. 48 CFR 18.116 - Service-disabled Veteran-owned Small Business (SDVOSB) sole source awards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Service-disabled Veteran... Available Acquisition Flexibilities 18.116 Service-disabled Veteran-owned Small Business (SDVOSB) sole source awards. Contracts may be awarded to Service-disabled Veteran-owned Small Business (SDVOSB...

  10. 48 CFR 19.1406 - Sole source awards to service-disabled veteran-owned small business concerns.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... service-disabled veteran-owned small business concerns. 19.1406 Section 19.1406 Federal Acquisition...-Disabled Veteran-Owned Small Business Procurement Program 19.1406 Sole source awards to service-disabled...-disabled veteran-owned small business concerns; (2) The anticipated award price of the contract, including...

  11. 48 CFR 18.116 - Service-disabled Veteran-owned Small Business (SDVOSB) sole source awards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Service-disabled Veteran... Available Acquisition Flexibilities 18.116 Service-disabled Veteran-owned Small Business (SDVOSB) sole source awards. Contracts may be awarded to Service-disabled Veteran-owned Small Business (SDVOSB...

  12. 40 CFR 149.111 - Funding to redesigned projects.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) SOLE SOURCE AQUIFERS Review of Projects Affecting the Edwards Underground Reservoir, A Designated Sole Source Aquifer in the San Antonio, Texas Area § 149.111 Funding to redesigned projects. After... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Funding to redesigned projects. 149...

  13. Molybdenum cofactor (chlorate-resistant) mutants of Klebsiella pneumoniae M5al can use hypoxanthine as the sole nitrogen source.

    PubMed Central

    Garzón, A; Li, J; Flores, A; Casadesus, J; Stewart, V

    1992-01-01

    Selection for chlorate resistance yields mol (formerly chl) mutants with defects in molybdenum cofactor synthesis. Complementation and genetic mapping analyses indicated that the Klebsiella pneumoniae mol genes are functionally homologous to those of Escherichia coli and occupy analogous genetic map positions. Hypoxanthine utilization in other organisms requires molybdenum cofactor as a component of xanthine dehydrogenase, and thus most chlorate-resistant mutants cannot use hypoxanthine as a sole source of nitrogen. Surprisingly, the K. pneumoniae mol mutants and the mol+ parent grew equally well with hypoxanthine as the sole nitrogen source, suggesting that K. pneumoniae has a molybdenum cofactor-independent pathway for hypoxanthine utilization. PMID:1400180

  14. Effect of specific amino acids on growth and aflatoxin production by Aspergillus parasiticus and Aspergillus flavus in defined media.

    PubMed Central

    Payne, G A; Hagler, W M

    1983-01-01

    Four amino acids were used as sole nitrogen sources or as supplements to ammonium sulfate, and casein and ammonium sulfate were used as sole nitrogen sources to examine their effects on aflatoxin production by Aspergillus parasiticus NRRL 2999 and Aspergillus flavus 3357 grown on synthetic liquid media. In general, when proline, asparagine, casein, and ammonium sulfate were used as sole nitrogen sources, they supported more growth and toxin production than tryptophan or methionine. However, proline stimulated more toxin production per gram of mycelium in stationary cultures than the other nitrogen sources, including the amino acid asparagine, which is generally recognized as supporting good aflatoxin production. The exact responses to individual nitrogen sources were influenced by the species of fungus and whether cultures were stationary or shaken. In shake cultures, but not in stationary cultures, increased growth was generally associated with increased toxin production. PMID:6416168

  15. Do sophisticated epistemic beliefs predict meaningful learning? Findings from a structural equation model of undergraduate biology learning

    NASA Astrophysics Data System (ADS)

    Lee, Silvia Wen-Yu; Liang, Jyh-Chong; Tsai, Chin-Chung

    2016-10-01

    This study investigated the relationships among college students' epistemic beliefs in biology (EBB), conceptions of learning biology (COLB), and strategies of learning biology (SLB). EBB includes four dimensions, namely 'multiple-source,' 'uncertainty,' 'development,' and 'justification.' COLB is further divided into 'constructivist' and 'reproductive' conceptions, while SLB represents deep strategies and surface learning strategies. Questionnaire responses were gathered from 303 college students. The results of the confirmatory factor analysis and structural equation modelling showed acceptable model fits. Mediation testing further revealed two paths with complete mediation. In sum, students' epistemic beliefs of 'uncertainty' and 'justification' in biology were statistically significant in explaining the constructivist and reproductive COLB, respectively; and 'uncertainty' was statistically significant in explaining the deep SLB as well. The results of mediation testing further revealed that 'uncertainty' predicted surface strategies through the mediation of 'reproductive' conceptions; and the relationship between 'justification' and deep strategies was mediated by 'constructivist' COLB. This study provides evidence for the essential roles some epistemic beliefs play in predicting students' learning.

  16. 48 CFR 819.7007 - Sole source awards to service-disabled veteran-owned small business concerns.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... service-disabled veteran-owned small business concerns. 819.7007 Section 819.7007 Federal Acquisition...-Disabled Veteran-Owned and Veteran-Owned Small Business Acquisition Program 819.7007 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to...

  17. 48 CFR 819.7007 - Sole source awards to service-disabled veteran-owned small business concerns.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... service-disabled veteran-owned small business concerns. 819.7007 Section 819.7007 Federal Acquisition...-Disabled Veteran-Owned and Veteran-Owned Small Business Acquisition Program 819.7007 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to...

  18. 48 CFR 819.7007 - Sole source awards to service-disabled veteran-owned small business concerns.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... service-disabled veteran-owned small business concerns. 819.7007 Section 819.7007 Federal Acquisition...-Disabled Veteran-Owned and Veteran-Owned Small Business Acquisition Program 819.7007 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to...

  19. 48 CFR 819.7007 - Sole source awards to service-disabled veteran-owned small business concerns.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... service-disabled veteran-owned small business concerns. 819.7007 Section 819.7007 Federal Acquisition...-Disabled Veteran-Owned and Veteran-Owned Small Business Acquisition Program 819.7007 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to...

  20. 48 CFR 819.7007 - Sole source awards to service-disabled veteran-owned small business concerns.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... service-disabled veteran-owned small business concerns. 819.7007 Section 819.7007 Federal Acquisition...-Disabled Veteran-Owned and Veteran-Owned Small Business Acquisition Program 819.7007 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to...

  1. 40 CFR 149.109 - Decision under section 1424(e).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) SOLE SOURCE AQUIFERS Review of Projects Affecting the Edwards Underground Reservoir, A Designated Sole Source Aquifer in the San Antonio, Texas Area § 149.109 Decision under section 1424(e). (a... hazard to public health is not sufficiently great so as to prevent commitment of Federal funding to the...

  2. 75 FR 12175 - Application(s) for Duty-Free Entry of Scientific Instruments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-15

    ..., micro and nano-sized phenomena from a variety of sources. The samples will be fixed, sectioned and attached to grids to be viewed in the instrument. Justification for Duty-Free Entry: There are no domestic...

  3. How do pregnant women justify smoking? A qualitative study with implications for nurses' and midwives' anti-tobacco interventions.

    PubMed

    Goszczyńska, Eliza; Knol-Michałowska, Kamila; Petrykowska, Alicja

    2016-07-01

    To research the subjective lay justifications expressed by smoking pregnant women to explain why they use cigarettes during pregnancy and to determine a typology for these justifications. Smoking pregnant mothers' awareness of the detrimental effects of smoking on foetal health frequently is a source of stress and cognitive dissonance (stemming from the contrast between viewing themselves as responsible mothers and smokers). One possible way to reduce these unpleasant feelings is acceptance or creation of beliefs allowing them to explain rationally why they continue this behaviour during pregnancy. Qualitative design. Thematic analysis of the content of posts from the three largest Polish parenting on-line forums written between the time they were founded and 12 November 2012. The data were collected between September - October 2012. During the analysis of the selected 73 posts, each of which included subjective explanations of smoking during pregnancy, 151 fragments, each containing one lay justification, were identified and analysed. Thirty-five subthemes of lay justifications assigned to two main themes were developed. The first main theme includes convictions that undermine the need to break the nicotine addiction and the positive aspects resulting from quitting. The second main theme comprises beliefs that question the possibility to abstain from smoking and exaggerate the barriers in the process of quitting. The creation of a typology of lay justifications might help nurses and midwives perform more effective anti-tobacco interventions geared specifically towards the thought patterns typical of pregnant women. © 2016 John Wiley & Sons Ltd.

  4. Evaluating the American Nurses Association's arguments against nurse participation in assisted suicide.

    PubMed

    Vogelstein, Eric

    2017-01-01

    This discussion paper critically assesses the American Nurses Association's stated arguments against nurse participation in assisted suicide, as found in its current (2013) position statement. Seven distinct arguments can be gleaned from the American Nurses Association's statement, based on (1) the American Nurses Association's Code of Ethics with Interpretive Statements and its injunction against nurses acting with the sole intent to end life, (2) the risks of abuse and misuse of assisted suicide, (3) nursing's social contract or covenant with society, (4) the contention that nurses must not harm their patients, (5) the sanctity of life, (6) the traditions of nursing, and (7) the fundamental goals of nursing. Each of these arguments is evaluated, and none are found to be convincing. This is crucial because the American Nurses Association's official stance on nurse participation in assisted suicide can have significant consequences for the well-being of nurses who care for patients in jurisdictions in which assisted suicide is legally available. The American Nurses Association should therefore have a strong and convincing justification for opposing the practice, if it is to take such a position. That it fails to evince such a justification in its official statement on the matter places a burden on the American Nurses Association to more strongly justify its position, or else abandon its stance against nurse participation in assisted suicide.

  5. The use of fermentation liquid of wastewater primary sedimentation sludge as supplemental carbon source for denitrification based on enhanced anaerobic fermentation.

    PubMed

    Liu, Feng; Tian, Yu; Ding, Yi; Li, Zhipeng

    2016-11-01

    Wastewater primary sedimentation sludge was prepared into fermentation liquid as denitrification carbon source, and the main components of fermentation liquid was short-chain volatile fatty acids. Meanwhile, the acetic acid and propionic acid respectively accounted for about 29.36% and 26.56% in short-chain volatile fatty acids. The performance of fermentation liquid, methanol, acetic acid, propionic acid and glucose used as sole carbon source were compared. It was found that the denitrification rate with fermentation liquid as carbon source was 0.17mgNO3(-)-N/mg mixed liquor suspended solid d, faster than that with methanol, acetic acid, and propionic acid as sole carbon source, and lower than that with glucose as sole carbon source. For the fermentation liquid as carbon source, the transient accumulation of nitrite was insignificantly under different initial total nitrogen concentration. Therefore, the use of fermentation liquid for nitrogen removal could improve denitrification rate, and reduce nitrite accumulation in denitrification process. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. [The justification of the level of public financing of health care to enhance health of population of the Russian Federation].

    PubMed

    Ulumbekova, G Z

    2013-01-01

    The article discusses the justification of management of public financing of health care in Russia. The technique of comparative analysis and evaluation of dependences between public health care financing and indicators of population health has been applied. It is demonstrated that to achieve the values of 75.6 years of life expectancy at birth and 11 of total mortality as target indicators of population health up to 2018 the amount of public health care financing is to be increased up to 1.5 times or up to 6% of GDP per year in prices of 2011. The sources of additional health care financing are proposed.

  7. Assessment of Uncertainty-Infused Scientific Argumentation

    ERIC Educational Resources Information Center

    Lee, Hee-Sun; Liu, Ou Lydia; Pallant, Amy; Roohr, Katrina Crotts; Pryputniewicz, Sarah; Buck, Zoë E.

    2014-01-01

    Though addressing sources of uncertainty is an important part of doing science, it has largely been neglected in assessing students' scientific argumentation. In this study, we initially defined a scientific argumentation construct in four structural elements consisting of claim, justification, uncertainty qualifier, and uncertainty…

  8. Appetite during consumption of enteral formula as a sole source of nutrition: the effect of supplementing pea-fibre and fructo-oligosaccharides.

    PubMed

    Whelan, Kevin; Efthymiou, Loukia; Judd, Patricia A; Preedy, Victor R; Taylor, Moira A

    2006-08-01

    Liquid enteral formulas are commonly used as a sole source of nutritional support of patients in hospital and community settings. Their effect on appetite has important consequences for dietary management of such patients and is likely to be affected by the formula composition. The aim of the present study was to compare appetite within healthy subjects consuming both a standard formula and one supplemented with pea-fibre (10 g/l) and fructo-oligosaccharide (FOS; 5 g/l) as a sole source of nutrition. Eleven healthy subjects consumed a standard formula or a pea-fibre/FOS formula as a sole source of nutrition for 14 d in a double-blind, cross-over trial. Appetite was recorded using standard 100 mm lines anchored at each end by a phrase denoting the most extreme appetite sensation. Consumption of the pea-fibre/FOS formula resulted in higher mean fullness (46 v. 37 mm, P=0.035), minimum fullness (13 v. 9 mm, P=0.024) and minimum satiety (12 v. 8 mm, P=0.012) compared to the standard formula. As there were no differences in macronutrient intake between formulas, these differences are likely to be due to supplementation with pea-fibre and FOS. The effect on appetite of the composition of an enteral formula, both with respect to nutrient content and functional components such as pea-fibre and FOS, may be an important aspect to consider in the dietary management of patients consuming enteral formula as a sole source of nutrition.

  9. [Effects of carbon sources changes on the property and morphology of 2,4-D degraded aerobic sludge granules].

    PubMed

    Ma, Jing-Yun; Quan, Xian-Chun; Xiong, Wei-Cong

    2010-11-01

    This study investigated the changes of the morphology, structure, and capability of removing the target contamination of the aerobic granules pre-cultured with mixed substrates of glucose and 2,4-dichlorophenoxyacetic acid (2,4-D) in a long-time running sequence batch reactor (SBR), when the carbon source transformed into the sole carbon source of 2,4-D. Results showed that when the substrate turned to the sole carbon source of 2,4-D, the aerobic granules still maintained a strong degradation ability to the target contamination; a 2,4-D removal percentage of 99.2% -100% and an average COD removal rate of 85.6% were achieved at the initial 2,4-D concentration of 361-564 mg/L. Carbon source transformation caused certain damages to the original aerobic granule structure, made some parts of granules disintegrated, and led to granule size decline from 513 microm to 302 microm. However, those granules maintained the main body, re-aggregated and grew after a period of adaptation due to their strong resistance to toxicity. Aerobic granules capable of utilizing 2,4-D as the sole carbon source with a good settling ability (SYI 20-40 mL/g) and a mean diameter of 489 microm were finally obtained in this study. Scanning electron microscope (SEM) observation showed that the diversity of granule microbial species was declined when turned to the sole carbon source.

  10. Production performance and milk fatty acids profile in grazing dairy cows offered ground corn or liquid molasses as the sole supplemental nonstructural carbohydrate source

    USDA-ARS?s Scientific Manuscript database

    The objective of this study was to compare the effects of corn meal or liquid molasses fed as the sole supplemental nonstructural carbohydrate source on milk yield and composition, milk fatty acids, and N use efficiency in grazing dairy cows. Ten multiparous organically-certified Jersey cows averagi...

  11. Solving the multi-frequency electromagnetic inverse source problem by the Fourier method

    NASA Astrophysics Data System (ADS)

    Wang, Guan; Ma, Fuming; Guo, Yukun; Li, Jingzhi

    2018-07-01

    This work is concerned with an inverse problem of identifying the current source distribution of the time-harmonic Maxwell's equations from multi-frequency measurements. Motivated by the Fourier method for the scalar Helmholtz equation and the polarization vector decomposition, we propose a novel method for determining the source function in the full vector Maxwell's system. Rigorous mathematical justifications of the method are given and numerical examples are provided to demonstrate the feasibility and effectiveness of the method.

  12. 5 CFR 890.1048 - Waiver of debarment for a provider that is the sole source of health care services in a community.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Waiver of debarment for a provider that... HEALTH BENEFITS PROGRAM Administrative Sanctions Imposed Against Health Care Providers Exceptions to the Effect of Debarments § 890.1048 Waiver of debarment for a provider that is the sole source of health care...

  13. Taking the New Curriculum Outdoors

    ERIC Educational Resources Information Center

    Forsey, Katherine

    2014-01-01

    A review of research on outdoor learning by Rickinson "et al." (2004) highlights the demonstrable educational benefits and provides a source of support, justification and an evidence base for educators looking to undertake more learning outside the classroom. Bird (2004) also reviewed the widely reported health benefits of outdoor…

  14. Improving nitrogen management for corn in southern Idaho and southwest Oregon

    USDA-ARS?s Scientific Manuscript database

    Funding is being sought from multiple sources to update nitrogen fertilizer recommendations for irrigated corn in southern Idaho and southwest Oregon. This paper summarizes the justifications and main objectives of this proposed research. Nitrogen needs to be correctly managed in corn production sys...

  15. Do Sophisticated Epistemic Beliefs Predict Meaningful Learning? Findings from a Structural Equation Model of Undergraduate Biology Learning

    ERIC Educational Resources Information Center

    Lee, Silvia Wen-Yu; Liang, Jyh-Chong; Tsai, Chin-Chung

    2016-01-01

    This study investigated the relationships among college students' epistemic beliefs in biology (EBB), conceptions of learning biology (COLB), and strategies of learning biology (SLB). EBB includes four dimensions, namely "multiple-source," "uncertainty," "development," and "justification." COLB is further…

  16. The Water Maser in II Zw 96: Scientific Justification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wiggins, Brandon Kerry

    We propose a VLBI search to image and locate the water emission in II Zw 96. We propose 3 sites within II Zw 96 for VLBI followup (see the proposed target listing below). We request 2.5 hours of on-source integration time with the VLBA per source. The array will achieve ~ 65µJy sensitivity in K band in this time which will be sufficient to detect luminous water maser features.

  17. Intelligence Sharing in Counterproliferation

    DTIC Science & Technology

    2007-09-01

    Claims Alleged Mobile WMD Plants Solely for ‘ Agrochemicals ,” Spiegel Online, Hamburg, Germany. Translated by OpenSource.gov https...Knauer, Sebastian. "German Site Claims Alleged Mobile WMD Plants Solely for Agrochemicals ." Spiegel Online. https://www.opensource.gov (accessed June

  18. Role of L-lysine-alpha-ketoglutarate aminotransferase in catabolism of lysine as a nitrogen source for Rhodotorula glutinis.

    PubMed Central

    Kinzel, J J; Winston, M K; Bhattacharjee, J K

    1983-01-01

    Wild-type and saccharopine dehydrogenaseless mutant strains of Rhodotorula glutinis grew in minimal medium containing lysine as the sole nitrogen source and simultaneously accumulated, in the culture supernatant, large amounts of a product identified as alpha-aminoadipic-delta-semialdehyde. The saccharopine dehydrogenase and pipecolic acid oxidase levels remained unchanged in wild-type cells grown in the presence of ammonium or lysine as the nitrogen source. Lysine-alpha-ketoglutarate aminotransferase activity was demonstrated in ammonium-grown cells. This activity was depressed in cells grown in the presence of lysine as the sole source of nitrogen. PMID:6408065

  19. Epistemic Beliefs about Justification Employed by Physics Students and Faculty in Two Different Problem Contexts

    NASA Astrophysics Data System (ADS)

    Çağlayan Mercan, Fatih

    2012-06-01

    This study examines the epistemic beliefs about justification employed by physics undergraduate and graduate students and faculty in the context of solving a standard classical physics problem and a frontier physics problem. Data were collected by a think-aloud problem solving session followed by a semi-structured interview conducted with 50 participants, 10 participants at freshmen, seniors, masters, PhD, and faculty levels. Seven modes of justification were identified and used for exploring the relationships between each justification mode and problem context, and expertise level. The data showed that justification modes were not mutually exclusive and many respondents combined different modes in their responses in both problem contexts. Success on solving the standard classical physics problem was not related to any of the justification modes and was independent of expertise level. The strength of the association across the problem contexts for the authoritative, rational, and empirical justification modes fell in the medium range and for the modeling justification mode fell in the large range of practical significance. Expertise level was not related with the empirical and religious justification modes. The strength of the association between the expertise level and the authoritative, rational, experiential, and relativistic justification modes fell in the medium range, and the modeling justification mode fell in the large range of practical significance. The results provide support for the importance of context for the epistemic beliefs about justification and are discussed in terms of the implications for teaching and learning science.

  20. Academic Program Review--Concerns and Justification.

    ERIC Educational Resources Information Center

    Heldman, D. R.

    Academic program review should not be considered a new phenomenon in higher education; reviews of various types have been conducted on a continuing basis. The renewed importance of an organized effort has been stimulated by the inability of funding sources to maintain levels of support required to insure quality in all on-going programs. Current…

  1. Exploring the Relationship between High School Students' Physics-Related Personal Epistemologies and Self-Regulated Learning in Turkey

    ERIC Educational Resources Information Center

    Alpaslan, Muhammet Mustafa; Yalvac, Bugrahan; Loving, Cathleen C.; Willson, Victor

    2016-01-01

    This article reports on an empirical exploration of the relations and strengths among Turkish grades 9-11 students' (n = 209) personal epistemologies (justification of knowledge, certainty of knowledge, source of knowledge, development of knowledge), self-regulated learning (extrinsic motivation, intrinsic motivation, rehearsal, elaboration,…

  2. Psychological Sources of Systematic Rejection Among White and Black Adolescents.

    ERIC Educational Resources Information Center

    Long, Samuel

    In this study, individual-oriented and system-oriented models of systemic rejection among white and black adolescents are investigated. Systemic rejection is defined as attitudes of political alienation and political violence justification. Twelve hypotheses were generated and tested using survey data collected in May 1976 from a random sample of…

  3. Justification of radiographic examinations: What are the key issues?

    PubMed

    Vom, Jason; Williams, Imelda

    2017-09-01

    Justification of radiographic examinations is the practice of evaluating requested radiological examinations to assess for clinical merit and appropriateness based on clinical notes and patient information. This implies that justification in radiography requires the evaluation of requested examinations, the justification of exposures being applied and determining whether patients fit the recommended criteria for the procedure. Medico-legal requirements by the professional registration body, the Medical Radiation Practice Board of Australia (MRPBA), identify justification as an advocated and obligatory practice for radiographers. Yet, justification remains an inconsistent practice implemented amongst Australian radiographers. This review aims to identify associated barriers inhibiting the consistent practice of justification and the hesitance by radiographers in practicing justification responsibilities. It also recommends a change in workplace culture which encourages radiographers to accept a more autonomous role that cultivates critical thinking, reflection and research-informed decision making as justification will ultimately benefit patients. © 2017 The Authors. Journal of Medical Radiation Sciences published by John Wiley & Sons Australia, Ltd on behalf of Australian Society of Medical Imaging and Radiation Therapy and New Zealand Institute of Medical Radiation Technology.

  4. Aerobic biodegradation of the sulfonamide antibiotic sulfamethoxazole by activated sludge applied as co-substrate and sole carbon and nitrogen source.

    PubMed

    Müller, Elisabeth; Schüssler, Walter; Horn, Harald; Lemmer, Hilde

    2013-08-01

    Potential aerobic biodegradation mechanisms of the widely used polar, low-adsorptive sulfonamide antibiotic sulfamethoxazole (SMX) were investigated in activated sludge at bench scale. The study focused on (i) SMX co-metabolism with acetate and ammonium nitrate and (ii) SMX utilization when present as the sole carbon and nitrogen source. With SMX adsorption being negligible, elimination was primarily based on biodegradation. Activated sludge was able to utilize SMX both as a carbon and/or nitrogen source. SMX biodegradation was enhanced when a readily degradable energy supply (acetate) was provided which fostered metabolic activity. Moreover, it was raised under nitrogen deficiency conditions. The mass balance for dissolved organic carbon showed an incomplete SMX mineralization with two scenarios: (i) with SMX as a co-substrate, 3-amino-5-methyl-isoxazole represented the main stable metabolite and (ii) SMX as sole carbon and nitrogen source possibly yielded hydroxyl-N-(5-methyl-1,2-oxazole-3-yl)benzene-1-sulfonamide as a further metabolite. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. Aerobic Growth of Escherichia coli with 2,4,6-Trinitrotoluene (TNT) as the Sole Nitrogen Source and Evidence of TNT Denitration by Whole Cells and Cell-Free Extracts▿ †

    PubMed Central

    Stenuit, Ben; Eyers, Laurent; Rozenberg, Raoul; Habib-Jiwan, Jean-Louis; Agathos, Spiros N.

    2006-01-01

    Escherichia coli grew aerobically with 2,4,6-trinitrotoluene (TNT) as sole nitrogen source and caused TNT's partial denitration. This reaction was enhanced in nongrowing cell suspensions with 0.516 mol nitrite released per mol TNT. Cell extracts denitrated TNT in the presence of NAD(P)H. Isomers of amino-dimethyl-tetranitrobiphenyl were detected and confirmed with U-15N-labeled TNT. PMID:17012591

  6. Lean Six Sigma Project - Defense Logistics Agency/Honeywell Long-Term Contract Model Using One-Pass Pricing for Sole-Source Spare Parts

    DTIC Science & Technology

    2011-02-18

    Control Limit Lower Control Limit Reaction Plan 1 Complaints from other suppliers (synopsis, award) SCG During award process Identify Sole- Source...Parts 0.0 1.0 0.0 Evaluate complaint, if valid remove item from contract. 2 Tracking timeline for procurement/reviews SCG During pre- award process...Review Solicitation 100.0 Determine where the document stands in the approval process. Adjust milestones and followup . 3 FAR/DPAP guidance SCG

  7. System Justification, Mental Health, and Behavior Among Disadvantaged Mothers and Their Children

    PubMed Central

    Godfrey, Erin B.

    2014-01-01

    Integrating social psychological research with work in child development, this study explored relationships between system justification (Jost & Banaji, 1994), maternal mental health and child externalizing behavior among low-income immigrants and racial/ethnic minorities. Dominican, Mexican and African-American families (N = 239) were assessed when children were 14-, 24- and 36-months old. SEM was used to explore longitudinal relationships between maternal system justification and mental health and associations with child behavior. Earlier mental health was negatively related to later system justification and system justification was negatively related to children’s externalizing behavior. Implications for system justification theory, child development and immigration are discussed. PMID:25035527

  8. 48 CFR 2406.304 - Approval of the justification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Approval of the justification. 2406.304 Section 2406.304 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN... 2406.304 Approval of the justification. (c) A class justification for other than full and open...

  9. Moral vindications.

    PubMed

    Kumar, Victor

    2017-10-01

    Psychologists and neuroscientists have recently been unearthing the unconscious processes that give rise to moral intuitions and emotions. According to skeptics like Joshua Greene, what has been found casts doubt on many of our moral beliefs. However, a new approach in moral psychology develops a learning-theoretic framework that has been successfully applied in a number of other domains. This framework suggests that model-based learning shapes intuitions and emotions. Model-based learning explains how moral thought and feeling are attuned to local material and social conditions. Philosophers can draw on these explanations, in some cases, in order to vindicate episodes of moral change. Explanations can support justifications by showing that they are not mere rationalizations. In addition, philosophical justifications are a fertile source for empirical hypotheses about the rational learning mechanisms that shape moral intuitions and emotions. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. [JUSTIFICATION OF USING EQUIVALENCE OF THE INDICES OF QUALITY, SAFETY, AND EFFICACY IN DEVELOPING BIOANALOGS].

    PubMed

    Niyazov, R R; Goryachev, D V; Gavrishina, E V; Romodanovskii, D P; Dranitsyna, M A

    2015-01-01

    We describe general principles of demonstrating biosimilarity, as well as selecting the biosimilarity margins. Any change in the structure of a biological molecule can modify its functional activity. Therefore, therapeutic equivalence between a biosimilar product and the corresponding reference product cannot be demonstrated using a single criterion. To demonstrate biosimilarity between two medicinal products, their various characteristics have to be evaluated which may, directly or indirectly, justify that clinically significant differences are absent. Insufficient understanding of 6ritical quality attributes brings a risk for the biosimilar product developer. This will either increase the number of non-clinical and clinical tests and trials needed or will result in awareness that the manufacturing process needs to be improved at the late stages of development, after investing significant resources in the development process. At the same time, the specification of the biological medicinal product cannot solely ensure safety and efficacy thereof. Properly characterized and controlled manufacturing process, which ensures consistency in its attributes not adequately controlled in specifications but influencing safety and efficacy profiles and showing their relevance in non-clinical tests and clinical trials, is an additional quality assurance factor. Justification of all development strategy details, including biosimilarity margins, has to be provided each time when the development process is initiated or when proceeding to the next steps. All problems encountered by the developer have to be resolved in close communication with the regulatory authority. In order to increase the quality of investigation and developer's adherence to good practices, clinical trial results should be published in detail.

  11. 48 CFR 1306.303-70 - Documentation and legal review of justifications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Documentation and legal review of justifications. 1306.303-70 Section 1306.303-70 Federal Acquisition Regulations System... Competition 1306.303-70 Documentation and legal review of justifications. The justification for providing for...

  12. 13 CFR 130.460 - Budget justification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Budget justification. 130.460... CENTERS § 130.460 Budget justification. The SBDC Director, as a part of the renewal application, or the... submit to the SBA Project Officer the budget justification for the upcoming budget period. The budget...

  13. Ideology and gender: observers' system justification and targets' gender as interactive predictors of citizenship expectations.

    PubMed

    Chiaburu, Dan S; Harris, T Brad; Smith, Troy A

    2014-01-01

    We integrate system justification and social role theory to explain how observers' system justification and target employees' gender interact to predict observers' expectations of targets' sportsmanship citizenship behaviors. In contrast with social role theory predictions, observers did not expect greater levels of sportsmanship from women compared to men. Yet observers expected more sportsmanship from women (a) when observers were ideologically motivated by gender-specific beliefs (gender-specific system justification; Study 1) and (b) when system justification was cued experimentally (Study 2). A heretofore-unexamined aspect, observers' ideology, modifies their expectations of sportsmanship citizenship across target genders. This has implications for system justification, social role, and organizational citizenship theoretical perspectives.

  14. Justifications for caregiving in white, Asian American, and native Hawaiian grandparents raising grandchildren.

    PubMed

    Yancura, Loriena A

    2013-01-01

    Race has been found to predict justifications for caregiving in family caregivers for older adults. However, little is known about this relationship in another type of family caregiver, Grandparents Raising Grandchildren (GRG). This study examined relationships between race and justifications for caregiving in Asian American, Native Hawaiian, and White GRG. A sample of 259 GRG registered as students' primary caregivers with a public school system completed a modified version of the 10-item Cultural Justifications for Caregiving (CJCG) scale. CJCG items did not load onto a single analytic factor. Two factors, custom and responsibility, emerged. Race was predictive of custom, with Native Hawaiian GRG having significantly higher scores than White or Asian American GRG. Native Hawaiian GRG also scored higher than Asian American, but not White, GRG on responsibility. Justifications for raising grandchildren appear to differ among groups based on racial identification. Findings elucidate cultural justification for caregiving in understudied GRG populations and suggest that justifications for caregiving are configured differently in GRG and family caregivers for older adults. Future studies should examine justifications for caregiving in GRG of other races.

  15. Validating justifications in preschool girls' and boys' friendship group talk: implications for linguistic and socio-cognitive development.

    PubMed

    Kyratzis, Amy; Ross, Tamara Shuqum; Koymen, S Bahar

    2010-01-01

    Children are believed to construct their causal theories through talk and interaction, but with the exception of a few studies, little or nothing is known about how young children justify and build theories of the world together with same-age peers through naturally occurring interaction, Children's sensitivity to when a pair or group of interlocutors who interact frequently together feel that a justification is needed, is an index of developing pragmatic competence (Goetz & Shatz, 1999) and may be influenced by interactive goals and gender identity positioning. Studies suggest that salient contexts for justifications for young children are disagreement and control (e.g. Veneziano & Sinclair, 1995) but researchers have been less recognizant of 'situations in which partners verbally assist in the construction of justifications as a means to maintain contact or create solidarity' (Goetz & Shatz, 1999: 722) as contexts for justifications. The present study examined the spontaneously produced justification constructions in the naturally occurring free play of five friendship groups of preschool-aged children (aged from 3 ; 6 to 5 ; 4), in terms of the motivating context of the justification, marking of the causal relationship with a connective, and causal theories accessed in the talk. Partner expansion (validating justifications) was a salient motivating context for justifications, especially in the talk of friendship groups of girls, and seemed to privilege greater marking of the causal relationship with a connective and less arbitrary reasoning. One group of girls varied their use of validating justifications depending on the theme of play. Results are discussed in terms of the implications of use of validating justifications for children's causal theory building with peers, linguistic development, and pragmatic development.

  16. [Kinetic simulation of enhanced biological phosphorus removal with fermentation broth as carbon source].

    PubMed

    Zhang, Chao; Chen, Yin-Guang

    2013-07-01

    As a high-quality carbon source, fermentation broth could promote the phosphorus removal efficiency in enhanced biological phosphorus removal (EBPR). The transformation of substrates in EBPR fed with fermentation broth was well simulated using the modified activated sludge model No. 2 (ASM2) based on the carbon source metabolism. When fermentation broth was used as the sole carbon source, it was found that heterotrophic bacteria acted as a promoter rather than a competitor to the phosphorus accumulating organisms (PAO). When fermentation broth was used as a supplementary carbon source of real municipal wastewater, the wastewater composition was optimized for PAO growth; and the PAO concentration, which was increased by 3.3 times compared to that in EBPR fed with solely real municipal wastewater, accounting for about 40% of the total biomass in the reactor.

  17. Glutamate Dehydrogenase from Apodachlya (Oomycetes) 1

    PubMed Central

    Price, Jeffrey S.; Gleason, Frank H.

    1972-01-01

    A glutamate dehydrogenase specific for nicotinamide-adenine-dinucleotide has been purified 50-fold from Apodachlya brachynema (Leptomitales). Certain physical, chemical, and kinetic properties of this enzyme have been studied, particularly specificity for coenzymes and substrates. With glucose as the sole carbon source, the synthesis of glutamate dehydrogenase was repressed, whereas glutamate, proline, alanine, or ornithine plus aspartate as sole carbon sources induced synthesis of the enzyme. These data indicate that the function of this enzyme is primarily degradative, although there is no evidence for a nicotinamide-adenine-dinucleotide-phosphate-specific biosynthetic glutamate dehydrogenase in Apodachlya. PMID:16657902

  18. Plasma Diagnostics: Use and Justification in an Industrial Environment

    NASA Astrophysics Data System (ADS)

    Loewenhardt, Peter

    1998-10-01

    The usefulness and importance of plasma diagnostics have played a major role in the development of plasma processing tools in the semiconductor industry. As can be seen through marketing materials from semiconductor equipment manufacturers, results from plasma diagnostic equipment can be a powerful tool in selling the technological leadership of tool design. Some diagnostics have long been used for simple process control such as optical emission for endpoint determination, but in recent years more sophisticated and involved diagnostic tools have been utilized in chamber and plasma source development and optimization. It is now common to find an assortment of tools at semiconductor equipment companies such as Langmuir probes, mass spectrometers, spatial optical emission probes, impedance, ion energy and ion flux probes. An outline of how the importance of plasma diagnostics has grown at an equipment manufacturer over the last decade will be given, with examples of significant and useful results obtained. Examples will include the development and optimization of an inductive plasma source, trends and hardware effects on ion energy distributions, mass spectrometry influences on process development and investigations of plasma-wall interactions. Plasma diagnostic focus, in-house development and proliferation in an environment where financial justification requirements are both strong and necessary will be discussed.

  19. The Effects of General System Justification on Corruption Perception and Intent

    PubMed Central

    Tan, Xuyun; Liu, Li; Huang, Zhenwei; Zheng, Wenwen; Liang, Yuan

    2016-01-01

    Previous research stresses that system justifying belief can weaken corruption perception, by this possibly fostering unjust behaviors. However, general results of the effect of general system justification on corruption are ambiguous, indicating also a lessening impact. We conducted a line of studies trying to elucidate these circumstances by testing the effect of general system justification on corruption perception and intention. In addition, we explored institutional trust as a possible mediator in this process. For this purpose, we conducted three studies. The first two studies examined the association between general system justification and corruption. In Study 1, a correlational design was run using questionnaires to assess the relation between general system justification and corruption perception as well as corruption intention. In Study 2, an experimental design was conducted manipulating general system justification via exposure to high or low system threat condition, then measuring its effect on corruption perception and corrupt intention. In Study 3, two sub-studies using correlational and experimental designs were run to explore the mediating role of institutional trust, respectively. Results replicated former studies showing that general system justification is negatively associated with corruption perception. However, they also showed a negative correlation with corrupt intention. Furthermore, they showed that institutional trust mediated the relation between general system justification and corruption. We suggest to consider these findings to further elucidate the psychological basis underlying different effects of general system justification on human behaviors. PMID:27507954

  20. The Effects of General System Justification on Corruption Perception and Intent.

    PubMed

    Tan, Xuyun; Liu, Li; Huang, Zhenwei; Zheng, Wenwen; Liang, Yuan

    2016-01-01

    Previous research stresses that system justifying belief can weaken corruption perception, by this possibly fostering unjust behaviors. However, general results of the effect of general system justification on corruption are ambiguous, indicating also a lessening impact. We conducted a line of studies trying to elucidate these circumstances by testing the effect of general system justification on corruption perception and intention. In addition, we explored institutional trust as a possible mediator in this process. For this purpose, we conducted three studies. The first two studies examined the association between general system justification and corruption. In Study 1, a correlational design was run using questionnaires to assess the relation between general system justification and corruption perception as well as corruption intention. In Study 2, an experimental design was conducted manipulating general system justification via exposure to high or low system threat condition, then measuring its effect on corruption perception and corrupt intention. In Study 3, two sub-studies using correlational and experimental designs were run to explore the mediating role of institutional trust, respectively. Results replicated former studies showing that general system justification is negatively associated with corruption perception. However, they also showed a negative correlation with corrupt intention. Furthermore, they showed that institutional trust mediated the relation between general system justification and corruption. We suggest to consider these findings to further elucidate the psychological basis underlying different effects of general system justification on human behaviors.

  1. Just Doing Business: Modern Racism and Obedience to Authority as Explanations for Employment Discrimination.

    PubMed

    Brief; Dietz; Cohen; Pugh; Vaslow

    2000-01-01

    In two experiments, we investigated the effects of prejudice (in the form of modern racism) and business justifications by authority figures (i.e., organizational superiors) to discriminate against minorities (Blacks in our research) in hiring situations. As expected, business justifications by legitimate authority figures led to participants' obedience in the form of discrimination relative to a no-justification condition and, in the second experiment, also relative to a condition in which the business justification came from an illegitimate authority figure. Moreover, in both experiments, as expected, modern racism did not have a main effect on discrimination, but interacted with business justifications such that modern racism predicted discrimination when a legitimate authority figure provided a business-related justification for such discrimination but not in the absence of such a justification. These results are discussed in terms of their theoretical implications for understanding prejudice and obedience to authority in organizations and in terms of their practical implications for addressing the problem of discrimination in the workplace. Copyright 2000 Academic Press.

  2. 46 CFR 112.25-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-3 Normal source for...

  3. 46 CFR 112.30-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....30-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-3 Normal source for emergency loads. (a) The normal source...

  4. 46 CFR 112.25-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ....25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-3 Normal source for...

  5. 46 CFR 112.30-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....30-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-3 Normal source for emergency loads. (a) The normal source...

  6. 46 CFR 112.30-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ....30-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-3 Normal source for emergency loads. (a) The normal source...

  7. 46 CFR 112.30-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....30-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-3 Normal source for emergency loads. (a) The normal source...

  8. 46 CFR 112.25-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-3 Normal source for...

  9. 46 CFR 112.30-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....30-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-3 Normal source for emergency loads. (a) The normal source...

  10. 46 CFR 112.25-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-3 Normal source for...

  11. 46 CFR 112.25-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-3 Normal source for...

  12. Breastfeeding as the sole source of milk for 6 months and adolescent bone mineral density.

    PubMed

    Blanco, E; Burrows, R; Reyes, M; Lozoff, B; Gahagan, S; Albala, C

    2017-10-01

    Little is known regarding the relationship between early life factors and bone mineral density (BMD). We found a positive association between breastfeeding for at least 6 months, without formula supplementation, and whole body adolescent BMD z-score. The aim of the study is to assess the role of breastfeeding BF on adolescent bone mineral density (BMD) in a cohort prospectively followed since infancy. We studied 679 participants from an infancy iron deficiency anemia preventive trial in Santiago, Chile, followed to adolescence. Breast and bottle feeding were ascertained weekly from 4 to 12 months. At 16 years, whole body BMD was assessed by DEXA. Using linear regression, we evaluated associations between BF duration and BF as the sole source of milk and adolescent BMD z-score, adjusting for possible infancy, adolescent, and background confounders. Mean birth weight and length were 3.5 (0.3) kg and 50.7 (1.6) cm. For at least 6 months, BF was the sole source of milk for 26.3% and with supplementation for 36.7%. For 37%, BF was provided for less than 6 months. Mean 16-year BMD z-score was 0.25 (1.0). Covariates included male sex, birth length, and gestational age. BF as the sole source of milk ≥6 months, compared to BF < 6 months, was associated with higher adolescent BMD z-score adjusting for covariates (β = 0.29, p < 0.05). Mixed BF was not significantly related to adolescent BMD z-score (β = 0.06, p = 0.47). For every 30 days of BF as the sole source of milk, adolescent BMD z-score increased by 0.03 (p = 0.01). BF without formula supplementation for at least 6 months was associated with higher adolescent BMD z-score and a suggestive trend in the same direction for BMD suggests that exclusivity and duration of BF may play a role in adolescent bone health.

  13. Biodegradation of munitions compounds by a sulfate reducing bacterial enrichment culture

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boopathy, R.; Manning, J.

    1997-08-01

    The degradation of several munitions compounds was studied. The compounds included 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine, octahydro-1,3,5,7-tetranitro-1,3,5,7-tetraazocine, 2,4,6-trinitrobenzene (TNB), and 2,4-dinitrotoluene. All of the compounds studied were degraded by the sulfate reducing bacterial (SRB) enrichment culture. The SRB culture did not use the munitions compounds as their sole source of carbon. However, all the munitions compounds tested served as the sole source of nitrogen for the SRB culture. Degradation of munitions compounds was achieved by a co-metabolic process. The SRB culture used a variety of carbon sources including pyruvate, ethanol, formate, lactate, and H{sub 2}-CO{sub 2}. The SRB culture was an incompletemore » oxidizer, unable to carry out the terminal oxidation of organic substrates to CO{sub 2} as the sole product, and it did not use acetate or methanol as a carbon source. In addition to serving as nitrogen sources, the munitions compounds also served as electron acceptors in the absence of sulfate. A soil slurry experiment with 5% and 10% munitions compounds-contaminated soil showed that the contaminant TNT was metabolized by the SRB culture in the presence of pyruvate as electron donor. This culture may be useful in decontaminating munitions compounds-contaminated soil and water under anaerobic conditions.« less

  14. A Cost Model for Air Force Institute of Technology Programs.

    DTIC Science & Technology

    1979-09-01

    Patterson AFB OH, September 1977. ADA 047662. 16. Horngren , Charles T. Cost Accounting , A Managerial Emphasis. Englewood Cliffs NJ: Prentice Hall, Inc...25 S . Categorical Breakdown of AFIT Cost Matrix ....... .................. . 26 6. Elemental Breakdown of AFIT Direct Cost Category...maximum use of existing data sources such as the Air Force Accounting System for Operations. Justification for Research In past years, cost studies

  15. Neutron die-away experiment for remote analysis of the surface of the moon and the planets, phase 3

    NASA Technical Reports Server (NTRS)

    Mills, W. R.; Allen, L. S.

    1972-01-01

    Continuing work on the two die-away measurements proposed to be made in the combined pulsed neutron experiment (CPNE) for analysis of lunar and planetary surfaces is described. This report documents research done during Phase 3. A general exposition of data analysis by the least-squares method and the related problem of the prediction of variance is given. A data analysis procedure for epithermal die-away data has been formulated. In order to facilitate the analysis, the number of independent material variables has been reduced to two: the hydrogen density and an effective oxygen density, the latter being determined uniquely from the nonhydrogeneous elemental composition. Justification for this reduction in the number of variables is based on a set of 27 new theoretical calculations. Work is described related to experimental calibration of the epithermal die-away measurement. An interim data analysis technique based solely on theoretical calculations seems to be adequate and will be used for future CPNE field tests.

  16. Routine admission laboratory testing for general medical patients.

    PubMed

    Hubbell, F A; Frye, E B; Akin, B V; Rucker, L

    1988-06-01

    We evaluated the usefulness of commonly ordered routine admission laboratory tests in 301 patients admitted consecutively to the internal medicine wards of a university teaching hospital. Using a consensus analysis approach, three Department of Medicine faculty members reviewed the charts of admitted patients to determine the impact of the test results on patient care. The evaluated tests were the urinalysis, hematocrit, white blood cell count, platelet count, six-factor automated multiple analysis (serum sodium, potassium, chloride, bicarbonate, glucose, and blood urea nitrogen), prothrombin time, partial thromboplastin time, chest x-ray, and electrocardiogram. Forty-five percent of the 3,684 tests were ordered for patients without recognizable medical indications. Twelve percent of these routine tests were abnormal, 5% led to additional laboratory testing, but only 0.5% led to change in the treatment of patients. We conclude that the impact of routine admission laboratory testing on patient care is very small and that there is little justification for ordering tests solely because of hospital admission.

  17. Justifying molecular images in cell biology textbooks: From constructions to primary data.

    PubMed

    Serpente, Norberto

    2016-02-01

    For scientific claims to be reliable and productive they have to be justified. However, on the one hand little is known on what justification precisely means to scientists, and on the other the position held by philosophers of science on what it entails is rather limited; for justifications customarily refer to the written form (textual expressions) of scientific claims, leaving aside images, which, as many cases from the history of science show are relevant to this process. The fact that images can visually express scientific claims independently from text, plus their vast variety and origins, requires an assessment of the way they are currently justified and in turn used as sources to justify scientific claims in the case of particular scientific fields. Similarly, in view of the different nature of images, analysis is required to determine on what side of the philosophical distinction between data and phenomena these different kinds of images fall. This paper historicizes and documents a particular aspect of contemporary life sciences research: the use of the molecular image as vehicle of knowledge production in cell studies, a field that has undergone a significant shift in visual expressions from the early 1980s onwards. Focussing on textbooks as sources that have been overlooked in the historiography of contemporary biomedicine, the aim is to explore (1) whether the shift of cell studies, entailing a superseding of the optical image traditionally conceptualised as primary data, by the molecular image, corresponds with a shift of justificatory practices, and (2) to assess the role of the molecular image as primary data. This paper also explores the dual role of images as teaching resources and as resources for the construction of knowledge in cell studies especially in its relation to discovery and justification. Finally, this paper seeks to stimulate reflection on what kind of archival resources could benefit the work of present and future epistemic historians in particular those interested on the role of images as sources of training and knowledge production in scientific disciplines. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Polymorphism of Malassezia furfur.

    PubMed

    Salkin, I F; Gordon, M A

    1977-04-01

    Alterations in the morphologic and physiologic characters of 11 isolates of Pityrosporum orbiculare were noted upon prolonged maintenance in pure culture. Successive subculturing of each isolate resulted in its progressive conversion from globose (P. orbiculare) through ovoid to cylindrical (P. ovale) form. Globose forms utilized neither olive oil nor Tween 20 as a sole carbon source, nor KNO3 as a sole source of nitrogen, while ovoid and cylindrical forms utilized both of these carbon sources, and one of four strains of the cylindrical form assimilated KNO3. These results suggest that P. orbiculare and P. ovale are stages in the complex developmental cycle of a single species (Malassezia furfur), but the three names should be preserved until the life cycle is more fully understood.

  19. Characteristics and Implications of Diagnostic Justification Scores Based on the New Patient Note Format of the USMLE Step 2 CS Exam.

    PubMed

    Yudkowsky, Rachel; Park, Yoon Soo; Hyderi, Abbas; Bordage, Georges

    2015-11-01

    To determine the psychometric characteristics of diagnostic justification scores based on the patient note format of the United States Medical Licensing Examination Step 2 Clinical Skills exam, which requires students to document history and physical findings, differential diagnoses, diagnostic justification, and plan for immediate workup. End-of-third-year medical students at one institution wrote notes for five standardized patient cases in May 2013 (n = 180) and 2014 (n = 177). Each case was scored using a four-point rubric to rate each of the four note components. Descriptive statistics and item analyses were computed and a generalizability study done. Across cases, 10% to 48% provided no diagnostic justification or had several missing or incorrect links between history and physical findings and diagnoses. The average intercase correlation for justification scores ranged from 0.06 to 0.16; internal consistency reliability of justification scores (coefficient alpha across cases) was 0.38. Overall, justification scores had the highest mean item discrimination across cases. The generalizability study showed that person-case interaction (12%) and task-case interaction (13%) had the largest variance components, indicating substantial case specificity. The diagnostic justification task provides unique information about student achievement and curricular gaps. Students struggled to correctly justify their diagnoses; performance was highly case specific. Diagnostic justification was the most discriminating element of the patient note and had the greatest variability in student performance across cases. The curriculum should provide a wide range of clinical cases and emphasize recognition and interpretation of clinically discriminating findings to promote the development of clinical reasoning skills.

  20. 46 CFR 112.30-10 - Restoration of normal source potential.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Section 112.30-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-10 Restoration of normal source potential. When the potential...

  1. 46 CFR 112.30-10 - Restoration of normal source potential.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Section 112.30-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-10 Restoration of normal source potential. When the potential...

  2. 46 CFR 112.30-10 - Restoration of normal source potential.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 112.30-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-10 Restoration of normal source potential. When the potential...

  3. 46 CFR 112.30-10 - Restoration of normal source potential.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Section 112.30-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-10 Restoration of normal source potential. When the potential...

  4. 46 CFR 112.30-10 - Restoration of normal source potential.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Section 112.30-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-10 Restoration of normal source potential. When the potential...

  5. 40 CFR 69.31 - New exemptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... This exemption applies solely to the PSD major source baseline date and trigger date in the... applicable requirement that is triggered by, implemented or calculated from the PSD major source baseline... the Northern Mariana Islands, use January 13, 1997 as the PSD major source baseline date and trigger...

  6. 48 CFR 619.808-1 - Sole source.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... source. (a) If the acquisition is conducted under an MOU cited in 619.800, the 8(a) contractor is... the acquisition is conducted under an MOU cited in 619.800, the agency is delegated the authority to...

  7. 46 CFR 112.35-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....35-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-3 Normal source...

  8. 46 CFR 112.35-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....35-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-3 Normal source...

  9. 46 CFR 112.35-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....35-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-3 Normal source...

  10. 46 CFR 112.35-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....35-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-3 Normal source...

  11. 46 CFR 112.35-3 - Normal source for emergency loads.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ....35-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-3 Normal source...

  12. Theological reflections on the ethics of pain control among the terminally ill.

    PubMed

    Purdy, W

    1992-01-01

    Explores the reality of pain thru explications of the theological notions of "justification by pain," "justification by death," and "justification by faith." Notes particularly the facilitating role of the hospital chaplain in the understanding of pain and its possible Christian meanings.

  13. What We Talk About When We Talk About Morality: Deontological, Consequentialist, and Emotive Language Use in Justifications Across Foundation-Specific Moral Violations.

    PubMed

    Wheeler, Melissa A; Laham, Simon M

    2016-09-01

    Morality is inherently social, yet much extant work in moral psychology ignores the central role of social processes in moral phenomena. To partly address this, this article examined the content of persuasive moral communication-the way people justify their moral attitudes in persuasive contexts. Across two studies, we explored variation in justification content (deontological, consequentialist, or emotive) as a function of moral foundations. Using justification selection techniques (Study 1) and open-ended justification production (Study 2), results demonstrate a preference (a) for deontological appeals in justifications for the sanctity foundation, (b) for consequentialist appeals for the individualizing foundations (care and fairness), and (c) for emotive appeals in justifications for the binding foundations (loyalty, authority and sanctity). The present research questions the generality of inferences about the primacy of emotions/intuition in moral psychology research and highlights the important role of reasons in persuasive moral communication. © 2016 by the Society for Personality and Social Psychology, Inc.

  14. Explanation production by expert planners

    NASA Technical Reports Server (NTRS)

    Bridges, Susan; Jhannes, James D.

    1988-01-01

    Although the explanation capability of expert systems is usually listed as one of the distinguishing characteristics of these systems, the explanation facilities of most existing systems are quite primitive. Computer generated explanations are typically produced from canned text or by direct translation of the knowledge structures. Explanations produced in this manner bear little resemblance to those produced by humans for similar tasks. The focus of our research in explanation is the production of justifications for decisions by expert planning systems. An analysis of justifications written by people for planning tasks has been taken as the starting point. The purpose of this analysis is two-fold. First, analysis of the information content of the justifications will provide a basis for deciding what knowledge must be represented if human-like justifications are to be produced. Second, an analysis of the textual organization of the justifications will be used in the development of a mechanism for selecting and organizing the knowledge to be included in a computer-produced explanation. This paper describes a preliminary analysis done of justifications written by people for a planning task. It is clear that these justifications differ significantly from those that would be produced by an expert system by tracing the firing of production rules. The results from the text analysis have been used to develop an augmented phrase structured grammar (APSG) describing the organization of the justifications. The grammar was designed to provide a computationally feasible method for determining textual organization that will allow the necessary information to be communicated in a cohesive manner.

  15. Doing the Math: Supporting Student Justifications

    ERIC Educational Resources Information Center

    James, Carolyn; Philiben, Lyn; Knievel, Molly

    2016-01-01

    Teachers have found that engaging students in justification can help students deepen and retain mathematical knowledge, gain a greater sense of ownership over the material, and improve communication and representation skills (Staples, Bartlo, and Thanheiser 2012). Student engagement in a justification activity can also lead to more equitable…

  16. 16 CFR 240.15 - Cost justification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Cost justification. 240.15 Section 240.15 Commercial Practices FEDERAL TRADE COMMISSION GUIDES AND TRADE PRACTICE RULES GUIDES FOR ADVERTISING ALLOWANCES AND OTHER MERCHANDISING PAYMENTS AND SERVICES § 240.15 Cost justification. It is no defense to a...

  17. Historical Perspectives in Marketing Education: Justification and Implementation

    ERIC Educational Resources Information Center

    Petkus, Ed, Jr.

    2010-01-01

    This article provides a justification and an implementation plan for the establishment of a historical orientation across the undergraduate marketing curriculum. The justification for the historical perspective addresses three areas: tapping into the extensive body of knowledge in marketing history, practical implications, and critical thinking.…

  18. 48 CFR 806.304 - Approval of the justification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... justification. 806.304 Section 806.304 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 806.304....304(c), Table 806.304-1 provides the authorities who may approve a justification: Table 806.304.1...

  19. 48 CFR 2806.304 - Approval of the justification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... justification. 2806.304 Section 2806.304 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE Competition and Acquisition Planning COMPETITION REQUIREMENTS Other Than Full and Open Competition 2806.304...) Pursuant to FAR 6.304(c), a class justification for other than full and open competition shall be approved...

  20. Anencephalics as organ sources.

    PubMed

    Sytsma, S E

    1996-03-01

    In recent years, the need for infant organs for transplantation has increased. There is a growing recognition of the potential use of anencephalics as sources of organs. Prevalent arguments defending the use of live anencephalics for organ sources are identified and criticized. I argue that attempts to deny the applicability of the "dead-donor rule" are either question-begging or based on false premises and that attempts to skirt the Kantian dictum against treating others as a means only are not successful. I contend that the apparent utilitarian justification for live anencephalics as organ sources is unsatisfactory for two reasons: first, because it ignores the undermining effect the policy would have on parental values and sentiments central to social welfare; and second, because attempts to respond adequately to the slippery slope argument against live anencephalic use are unconvincing.

  1. 48 CFR 2406.304-70 - Approval of the justification-field procurements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Other Than Full and Open Competition 2406.304-70 Approval of the justification—field procurements. (a) The justification for other than full and open competition for field procurements shall be approved in... justification-field procurements. 2406.304-70 Section 2406.304-70 Federal Acquisition Regulations System...

  2. [Justification of violence as a mediator between exposure to violence and aggressive behavior in children].

    PubMed

    Orue, Izaskun; Calvete, Esther

    2012-02-01

    The aim of this study was to evaluate the mediating role of the justification of violence schema in the relationship between exposure to violence and reactive and proactive aggressive behavior. We differentiated between direct and indirect exposure in four contexts: home, neighborhood, school and TV. A total of 675 children, aged between 8 and 12 years, participated in the study. They answered questionnaires about exposure to violence, justification of violence, and proactive and reactive aggressive behavior in two waves six months apart. The results showed that witnessing violence at home and on TV predicted aggressive behavior, and this relationship was mediated by the justification of violence. Victimization in all contexts predicted aggressive behavior and this relationship was generally mediated by the justification of violence.

  3. IN-SITU THERMAL TREATMENT SYSTEM PERFORMANCE AND MASS REMOVAL METRICS AT FORT LEWIS

    EPA Science Inventory

    The EGDY is the source of a potentially expanding three mile long TCE plume in a sole source drinking water aquifer. Thermal remediation is being employed to reduce source mass loading to the dissolved phase aquifer plume and reduce the time to reach site cleanup goals. This is...

  4. LESSONS LEARNED FROM IN-SITU RESISTIVE HEATING OF TCE AT FORT LEWIS, WASHINGTON

    EPA Science Inventory

    The EGDY is the source of a potentially expanding, three mile long TCE plume in a sole source drinking water aquifer. Thermal remediation is being employed to reduce source mass loading to the dissolved phase aquifer plume and reduce the time to reach site cleanup goals. This i...

  5. Utilization of Dimethyl Sulfide as a Sulfur Source with the Aid of Light by Marinobacterium sp. Strain DMS-S1

    PubMed Central

    Fuse, Hiroyuki; Takimura, Osamu; Murakami, Katsuji; Yamaoka, Yukiho; Omori, Toshio

    2000-01-01

    Strain DMS-S1 isolated from seawater was able to utilize dimethyl sulfide (DMS) as a sulfur source only in the presence of light in a sulfur-lacking medium. Phylogenetic analysis based on 16S ribosomal DNA genes indicated that the strain was closely related to Marinobacterium georgiense. The strain produced dimethyl sulfoxide (DMSO), which was a main metabolite, and small amounts of formate and formaldehyde when grown on DMS as the sole sulfur source. The cells of the strain grown with succinate as a carbon source were able to use methyl mercaptan or methanesulfonate besides DMS but not DMSO or dimethyl sulfone as a sole sulfur source. DMS was transformed to DMSO primarily at wavelengths between 380 and 480 nm by heat-stable photosensitizers released by the strain. DMS was also degraded to formaldehyde in the presence of light by unidentified heat-stable factors released by the strain, and it appeared that strain DMS-S1 used the degradation products, which should be sulfite, sulfate, or methanesulfonate, as sulfur sources. PMID:11097944

  6. Nonlinear Real-Time Optical Signal Processing.

    DTIC Science & Technology

    1988-07-01

    Principal Investigator B. K. Jenkins Signal and Image Processing Institute University of Southern California Mail Code 0272 Los Angeles, California...ADDRESS (09% SteW. Mnd ZIP Code ) 10. SOURC OF FUNONG NUMBERS Bldg. 410, Bolling AFB PROGAM CT TASK WORK UNIT Washington, D.C. 20332 EEETP.aso o 11...TAB Unmnnncced Justification By Distribution/ I O’ Availablility Codes I - ’_ ji and/or 2 I Summary During the period 1 July 1987 - 30 June 1988, the

  7. Students' Problem Solving and Justification

    ERIC Educational Resources Information Center

    Glass, Barbara; Maher, Carolyn A.

    2004-01-01

    This paper reports on methods of students' justifications of their solution to a problem in the area of combinatorics. From the analysis of the problem solving of 150 students in a variety of settings from high-school to graduate study, four major forms of reasoning evolved: (1) Justification by Cases, (2) Inductive Argument, (3) Elimination…

  8. Student Perceptions of Justification in Two Disparate Domains: Education and Biology

    ERIC Educational Resources Information Center

    Dawson, Christi L.; Hennessey, Maeghan N.; Higley, Kelli

    2016-01-01

    This study investigated the perceptions of epistemic justification of students in two disparate domains of study to determine if any similarities and differences in their methods of justification exist. Two samples of students, or a total of 513 undergraduates from educational psychology (n = 193) and biology (n = 320) courses, completed a…

  9. College Students; Justification for Digital Piracy: A Mixed Methods Study

    ERIC Educational Resources Information Center

    Yu, Szde

    2012-01-01

    A mixed methods project was devoted to understanding college students' justification for digital piracy. The project consisted of two studies, a qualitative one and a quantitative one. Qualitative interviews were conducted to identify main themes in students' justification for digital piracy, and then the findings were tested in a quantitative…

  10. The Development of Justifications for Moral Judgements.

    ERIC Educational Resources Information Center

    Langford, Peter E.; Claydon, Leslie F.

    This document reports on two studies that used a novel approach to categorize justifications for moral judgments made by Australian subjects from 7 to 15 and from 7 to 21 years of age. The coding categories consisted of levels of abstraction and reflection. Level of abstraction was determined by the reference group used in justifications. Levels…

  11. Performing Arts Program, Badger High School: Justification, Proposal, Implementation, Stage One Implementation.

    ERIC Educational Resources Information Center

    Holmes, Dan

    This document presents a justification, proposal, and implementation plan for a comprehensive theatre arts program at Badger High School, Lake Geneva, Wisconsin that would offer a full schedule of amateur and professional arts programs involving the students and the community. The brief Justification section notes that every elementary and…

  12. Investigating the Development of Chinese Oral Explanation and Justification in Singapore Primary Students

    ERIC Educational Resources Information Center

    Yan, Jing

    2016-01-01

    Explanation and justification require cognitive ability which selects and organises relevant information in a logical way, and linguistic ability which enables speakers to encode the information with linguistic knowledge. This study aims to investigate the development of Chinese oral explanation and justification in Singapore primary students. The…

  13. R. S. Peters' "The Justification of Education" Revisited

    ERIC Educational Resources Information Center

    Cuypers, Stefaan E.

    2012-01-01

    In his 1973 paper "The Justification of Education" R. S. Peters aspired to give a non-instrumental justification of education. Ever since, his so-called "transcendental argument" has been under attack and most critics conclude that it does not work. They have, however, thrown the baby away with the bathwater, when they furthermore concluded that…

  14. A Comparison of Social Dominance Theory and System Justification: The Role of Social Status in 19 Nations.

    PubMed

    Vargas-Salfate, Salvador; Paez, Dario; Liu, James H; Pratto, Felicia; Gil de Zúñiga, Homero

    2018-07-01

    This study tests specific competing hypotheses from social dominance theory/realistic conflict theory (RCT) versus system justification theory about the role of social status. In particular, it examines whether system justification belief and effects are stronger among people with low socioeconomic status, and in less socially developed and unequal nations than among better-off people and countries. A cross-national survey was carried out in 19 nations from the Americas, Western and Eastern Europe, Asia, and Oceania using representative online samples ( N = 14,936, 50.15% women, M age = 41.61 years). At the individual level, system justification beliefs, right-wing authoritarianism, social dominance orientation, national identification, sociopolitical conservatism, sex, age, and social status were measured. At the national level, the human development index and the Gini index were used. Multilevel analyses performed indicated that results fit better with the social dominance/RCT approach, as system justification was higher in high-status and developed nations; further, associations between legitimizing ideologies and system justification were stronger among high-status people.

  15. On sanction-goal justifications: How and why deterrence justifications undermine rule compliance.

    PubMed

    Mooijman, Marlon; van Dijk, Wilco W; van Dijk, Eric; Ellemers, Naomi

    2017-04-01

    Authorities frequently justify their sanctions as attempts to deter people from rule breaking. Although providing a sanction justification seems appealing and harmless, we propose that a deterrence justification decreases the extent to which sanctions are effective in promoting rule compliance. We develop a theoretical model that specifies how and why this occurs. Consistent with our model, 5 experiments demonstrated that-compared with sanctions provided without a justification or sanctions provided with a just-deserts justification-sanction effectiveness decreased when sanctions were justified as attempts to deter people from rule breaking. This effect was mediated by people feeling distrusted by the authority. We further demonstrated that (a) the degree to which deterrence fostered distrust was attenuated when the sanction was targeted at others (instead of the participant) and (b) the degree to which distrust undermined rule compliance was attenuated when the authority was perceived as legitimate. We discuss the practical implications for authorities tasked with promoting rule compliance, and the theoretical implications for the literature on sanctions, distrust, and rule compliance. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  16. Production of polyhydroxybutyrate by the marine photosynthetic bacterium Rhodovulum sulfidophilum P5

    NASA Astrophysics Data System (ADS)

    Cai, Jinling; Wei, Ying; Zhao, Yupeng; Pan, Guanghua; Wang, Guangce

    2012-07-01

    The effects of different NaCl concentrations, nitrogen sources, carbon sources, and carbon to nitrogen molar ratios on biomass accumulation and polyhydroxybutyrate (PHB) production were studied in batch cultures of the marine photosynthetic bacterium Rhodovulum sulfidophilum P5 under aerobic-dark conditions. The results show that the accumulation of PHB in strain P5 is a growth-associated process. Strain P5 had maximum biomass and PHB accumulation at 2%-3% NaCl, suggesting that the bacterium can maintain growth and potentially produce PHB at natural seawater salinity. In the nitrogen source test, the maximum biomass accumulation (8.10±0.09 g/L) and PHB production (1.11±0.13 g/L and 14.62%±2.2 of the cell dry weight) were observed when peptone and ammonium chloride were used as the sole nitrogen source. NH{4/+}-N was better for PHB production than other nitrogen sources. In the carbon source test, the maximum biomass concentration (7.65±0.05 g/L) was obtained with malic acid as the sole carbon source, whereas the maximum yield of PHB (5.03±0.18 g/L and 66.93%±1.69% of the cell dry weight) was obtained with sodium pyruvate as the sole carbon source. In the carbon to nitrogen ratios test, sodium pyruvate and ammonium chloride were selected as the carbon and nitrogen sources, respectively. The best carbon to nitrogen molar ratio for biomass accumulation (8.77±0.58 g/L) and PHB production (6.07±0.25 g/L and 69.25%±2.05% of the cell dry weight) was 25. The results provide valuable data on the production of PHB by R. sulfidophilum P5 and further studies are on-going for best cell growth and PHB yield.

  17. 46 CFR 112.25-1 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-1 General. This subpart contains requirements applicable to...

  18. 46 CFR 112.25-1 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-1 General. This subpart contains requirements applicable to...

  19. 46 CFR 112.25-1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-1 General. This subpart contains requirements applicable to...

  20. 46 CFR 112.25-1 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-1 General. This subpart contains requirements applicable to...

  1. 46 CFR 112.25-1 - General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-1 General. This subpart contains requirements applicable to...

  2. 48 CFR 15.306 - Exchanges with offerors after receipt of proposals.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... negotiations may include bargaining. Bargaining includes persuasion, alteration of assumptions and positions... ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 15.... Negotiations are exchanges, in either a competitive or sole source environment, between the Government and...

  3. 48 CFR 15.306 - Exchanges with offerors after receipt of proposals.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... negotiations may include bargaining. Bargaining includes persuasion, alteration of assumptions and positions... ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 15.... Negotiations are exchanges, in either a competitive or sole source environment, between the Government and...

  4. 48 CFR 2901.603-70 - Responsibility of other government personnel.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... and open competition are satisfied to the maximum extent practicable. Sole source purchases may only... LABOR GENERAL DEPARTMENT OF LABOR ACQUISITION REGULATION SYSTEM Career Development, Contracting... being overly restrictive in accordance with FAR 11.002; (2) Competitive sources are solicited, evaluated...

  5. Mineralization of the Cyclic Nitramine Explosive Hexahydro-1,3,5-Trinitro-1,3,5-Triazine by Gordonia and Williamsia spp.

    PubMed Central

    Thompson, Karen T.; Crocker, Fiona H.; Fredrickson, Herbert L.

    2005-01-01

    Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is a cyclic nitroamine explosive that is a major component in many military high-explosive formulations. In this study, two aerobic bacteria that are capable of using RDX as the sole source of carbon and nitrogen to support their growth were isolated from surface soil. These bacterial strains were identified by their fatty acid profiles and 16S ribosomal gene sequences as Williamsia sp. KTR4 and Gordonia sp. KTR9. The physiology of each strain was characterized with respect to the rates of RDX degradation and [U-14C]RDX mineralization when RDX was supplied as a sole carbon and nitrogen source in the presence and absence of competing carbon and nitrogen sources. Strains KTR4 and KTR9 degraded 180 μM RDX within 72 h when RDX served as the only added carbon and nitrogen source while growing to total protein concentrations of 18.6 and 16.5 μg/ml, respectively. Mineralization of [U-14C]RDX to 14CO2 was 30% by strain KTR4 and 27% by KTR9 when RDX was the only added source of carbon and nitrogen. The addition of (NH4)2SO4 greatly inhibited KTR9's degradation of RDX but had little effect on that of KTR4. These are the first two pure bacterial cultures isolated that are able to use RDX as a sole carbon and nitrogen source. These two genera possess different physiologies with respect to RDX mineralization, and each can serve as a useful microbiological model for the study of RDX biodegradation with regard to physiology, biochemistry, and genetics. PMID:16332812

  6. 41 CFR 102-37.220 - Are there special types of surplus property that require written justification when submitting a...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Are there special types of surplus property that require written justification when submitting a transfer request? 102-37.220... types of surplus property that require written justification when submitting a transfer request? Yes, a...

  7. 41 CFR 102-37.220 - Are there special types of surplus property that require written justification when submitting a...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Are there special types of surplus property that require written justification when submitting a transfer request? 102-37.220... types of surplus property that require written justification when submitting a transfer request? Yes, a...

  8. 41 CFR 102-37.220 - Are there special types of surplus property that require written justification when submitting a...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Are there special types of surplus property that require written justification when submitting a transfer request? 102-37.220... types of surplus property that require written justification when submitting a transfer request? Yes, a...

  9. 41 CFR 102-37.220 - Are there special types of surplus property that require written justification when submitting a...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Are there special types of surplus property that require written justification when submitting a transfer request? 102-37.220... types of surplus property that require written justification when submitting a transfer request? Yes, a...

  10. 41 CFR 102-37.220 - Are there special types of surplus property that require written justification when submitting a...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Are there special types of surplus property that require written justification when submitting a transfer request? 102-37.220... types of surplus property that require written justification when submitting a transfer request? Yes, a...

  11. 41 CFR 102-5.95 - Is the comfort and/or convenience of an employee considered sufficient justification to authorize...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... convenience of an employee considered sufficient justification to authorize home-to-work transportation? 102-5...-to-Work Transportation § 102-5.95 Is the comfort and/or convenience of an employee considered sufficient justification to authorize home-to-work transportation? No, the comfort and/or convenience of an...

  12. 30 CFR 203.85 - What is in an economic viability and relief justification report?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What is in an economic viability and relief... Sulfur General § 203.85 What is in an economic viability and relief justification report? This report... economic viability and relief justification report must contain the following items for an oil and gas...

  13. 30 CFR 203.85 - What is in an economic viability and relief justification report?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What is in an economic viability and relief... Sulfur General § 203.85 What is in an economic viability and relief justification report? This report... economic viability and relief justification report must contain the following items for an oil and gas...

  14. 30 CFR 203.85 - What is in an economic viability and relief justification report?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What is in an economic viability and relief... Sulfur General § 203.85 What is in an economic viability and relief justification report? This report... economic viability and relief justification report must contain the following items for an oil and gas...

  15. 30 CFR 203.85 - What is in an economic viability and relief justification report?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What is in an economic viability and relief... Required Reports § 203.85 What is in an economic viability and relief justification report? This report... economic viability and relief justification report must contain the following items for an oil and gas...

  16. Justification as a Teaching and Learning Practice: Its (Potential) Multifacted Role in Middle Grades Mathematics Classrooms

    ERIC Educational Resources Information Center

    Staples, Megan E.; Bartlo, Joanna; Thanheiser, Eva

    2012-01-01

    Justification is a core mathematics practice. Although the purposes of justification in the mathematician community have been studied extensively, we know relatively little about its role in K-12 classrooms. This paper documents the range of purposes identified by 12 middle grades teachers who were working actively to incorporate justification…

  17. Identification of Justification Types and Discourse Markers in Turkish Language Teacher Candidates' Argumentative Texts

    ERIC Educational Resources Information Center

    Tiryaki, Esra Nur

    2017-01-01

    The purpose of this research is to identify discourse markers used in justification types in Turkish language teacher candidates' argumentative texts. Survey model was used since it was aimed to determine the categories into which support and refutation justifications are split and to identify the discourse markers which express these categories.…

  18. Breastfeeding and Mental and Motor Development at 5 ½ Years

    PubMed Central

    Clark, Katy M.; Castillo, Marcela; Calatroni, Agustin; Walter, Tomas; Cayazzo, Marisol; Pino, Paulina; Lozoff, Betsy

    2006-01-01

    Objective Breastfeeding is associated with better child development outcomes, but uncertainty remains primarily due to the close relationship between breastfeeding and socioeconomic status. This study assesses the issue in a low socioeconomic status sample where breastfeeding was close to universal. Methods 784 Chilean children were followed longitudinally from infancy. All but 4 were initially breastfed, 40% nursed beyond 12 months, and infant growth was normal. Child development was assessed at 5 ½ years by a cognitive, language, and motor test battery. The duration of breastfeeding as the sole milk source was analyzed as a continuous variable, adjusting for a comprehensive set of background factors. Results The relationship between breastfeeding and most 5 ½ -year developmental outcomes was non-linear, with poorer outcome for periods of breastfeeding as the sole milk source for < 2 months or > 8 months – statistically significant for language, motor, and one comprehensive cognitive test, with a suggestive trend for IQ. Conclusions The observed non-linear relationships showed that breastfeeding as the sole milk source for < 2 months or > 8 months, compared to 2–8 months, was associated with poorer development in this sample. The latter finding requires replication in other samples where long breastfeeding is common and socioeconomic status is relatively homogeneous. PMID:16530141

  19. 40 CFR 149.100 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 1424(e) and 1450 of the Public Health Service Act, as amended by the Safe Drinking Water Act, Pub. L... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) SOLE SOURCE... drinking water source for the San Antonio area and which, if contaminated, would create a significant...

  20. 40 CFR 149.100 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 1424(e) and 1450 of the Public Health Service Act, as amended by the Safe Drinking Water Act, Pub. L... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) SOLE SOURCE... drinking water source for the San Antonio area and which, if contaminated, would create a significant...

  1. Conidiation of Penicillium camemberti in submerged liquid cultures is dependent on the nitrogen source.

    PubMed

    Boualem, Khadidja; Labrie, Steve; Gervais, Patrick; Waché, Yves; Cavin, Jean-François

    2016-02-01

    To study the ability of a commercial Penicillium camemberti strain, used for Camembert type cheese ripening, to produce conidia during growth in liquid culture (LC), in media containing different sources of nitrogen as, industrially, conidia are produced by growth at the surface of a solid state culture because conidiation in stirred submerged aerobic LC is not known. In complex media containing peptic digest of meat, hyphae ends did not differentiate into phialides and conidia. Contrarily, in a synthetic media containing KNO3 as sole nitrogen source, hyphae ends differentiated into phialides producing 0.5 × 10(7) conidia/ml. Conidia produced in LC were 25 % less hydrophobic than conidia produced in solid culture, and this correlates with a seven-times-lower expression of the gene rodA encoding hydrophobin RodA in the mycelium grown in LC. Conidiation of P. camembertii is stimulated in iquid medium containing KNO3 as sole source of nitrogen and therefore opens up opportunities for using liquid medium in commercial productions.

  2. S5 Lipase: an organic solvent tolerant enzyme.

    PubMed

    Rahman, Raja Noor Zaliha Abdul; Baharum, Syarul Nataqain; Salleh, Abu Bakar; Basri, Mahiran

    2006-12-01

    In this study, an organic solvent tolerant bacterial strain was isolated. This strain was identified as Pseudomonas sp. strain S5, and was shown to degrade BTEX (Benzene, Toluene, Ethyl-Benzene, and Xylene). Strain S5 generates an organic solvent-tolerant lipase in the late logarithmic phase of growth. Maximum lipase production was exhibited when peptone was utilized as the sole nitrogen source. Addition of any of the selected carbon sources to the medium resulted in a significant reduction of enzyme production. Lower lipase generation was noted when an inorganic nitrogen source was used as the sole nitrogen source. This bacterium hydrolyzed all tested triglycerides and the highest levels of production were observed when olive oil was used as a natural triglyceride. Basal medium containing Tween 60 enhanced lipase production to the most significant degree. The absence of magnesium ions (Mg2+) in the basal medium was also shown to stimulate lipase production. Meanwhile, an alkaline earth metal ion, Na+, was found to stimulate the production of S5 lipase.

  3. Methanol Expression Regulator 1 (Mxr1p) Is Essential for the Utilization of Amino Acids as the Sole Source of Carbon by the Methylotrophic Yeast, Pichia pastoris.

    PubMed

    Sahu, Umakant; Rangarajan, Pundi N

    2016-09-23

    Unlike Saccharomyces cerevisiae, the methylotrophic yeast Pichia pastoris can assimilate amino acids as the sole source of carbon and nitrogen. It can grow in media containing yeast extract and peptone (YP), yeast nitrogen base (YNB) + glutamate (YNB + Glu), or YNB + aspartate (YNB + Asp). Methanol expression regulator 1 (Mxr1p), a zinc finger transcription factor, is essential for growth in these media. Mxr1p regulates the expression of several genes involved in the utilization of amino acids as the sole source of carbon and nitrogen. These include the following: (i) GDH2 encoding NAD-dependent glutamate dehydrogenase; (ii) AAT1 and AAT2 encoding mitochondrial and cytosolic aspartate aminotransferases, respectively; (iii) MDH1 and MDH2 encoding mitochondrial and cytosolic malate dehydrogenases, respectively; and (iv) GLN1 encoding glutamine synthetase. Synthesis of all these enzymes is regulated by Mxr1p at the level of transcription except GDH2, whose synthesis is regulated at the level of translation. Mxr1p activates the transcription of AAT1, AAT2, and GLN1 in cells cultured in YP as well as in YNB + Glu media, whereas transcription of MDH1 and MDH2 is activated in cells cultured in YNB + Glu but not in YP. A truncated Mxr1p composed of 400 N-terminal amino acids activates transcription of target genes in cells cultured in YP but not in YNB + Glu. Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  4. Efficient XML Interchange (EXI) Compression and Performance Benefits: Development, Implementation and Evaluation

    DTIC Science & Technology

    2010-03-01

    to a graphics card , and not the redesign of XML. The justification is that if XML is going to be prevalent, special optimized hardware is...the answer, similar to the specialized functions of a video card .  Given the Moore’s law that processing power doubles every few years, let the...and numerous multimedia players such as iTunes from Apple. These applications are free to use, but the source is restricted by software licenses

  5. Pulling the Religious Trigger: Iran’s End-Times Beliefs and Divine Justifications for Potential Action Against the United States

    DTIC Science & Technology

    2014-09-01

    current government. Moving to the regime’s current leadership , the literature survey mostly includes primary sources from Iran’s Supreme Leader, Ali...Office of the Secretary of Defense, published Mullahs, Guards, and Bonyads38: An Exploration of Iranian Leadership Dynamics. The book’s objective is...to provide a “framework to help policymakers and analysts better understand existing and evolving leadership dynamics driving Iranian decisionmaking

  6. 45 CFR 154.230 - Submission and posting of Final Justifications for unreasonable rate increases.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... information available to the public on its Web site for at least three years. (d) CMS will post all Final Justifications on the CMS Web site. This information will remain available to the public on the CMS Web site for... submitted in the Preliminary Justification supporting the rate increase; and (2) Prominently post on its Web...

  7. "Should We Kill the Grey Squirrels?" A Study Exploring Students' Justifications and Decision-Making

    ERIC Educational Resources Information Center

    Evagorou, Maria; Jimenez-Aleixandre, Maria Pilar; Osborne, Jonathan

    2012-01-01

    A problem that is still unexplored in the field of socioscientific issues (SSI) and that was explored in this study is how different students decide upon a SSI they are discussing, how their justifications change during the instruction and how they use (or not) the evidence from the learning environment to support their justifications. For the…

  8. Carbon utilization profiles of river bacterial strains facing sole carbon sources suggest metabolic interactions.

    PubMed

    Goetghebuer, Lise; Servais, Pierre; George, Isabelle F

    2017-05-01

    Microbial communities play a key role in water self-purification. They are primary drivers of biogenic element cycles and ecosystem processes. However, these communities remain largely uncharacterized. In order to understand the diversity-heterotrophic activity relationship facing sole carbon sources, we assembled a synthetic community composed of 20 'typical' freshwater bacterial species mainly isolated from the Zenne River (Belgium). The carbon source utilization profiles of each individual strain and of the mixed community were measured in Biolog Phenotype MicroArrays PM1 and PM2A microplates that allowed testing 190 different carbon sources. Our results strongly suggest interactions occurring between our planktonic strains as our synthetic community showed metabolic properties that were not displayed by its single components. Finally, the catabolic performances of the synthetic community and a natural community from the same sampling site were compared. The synthetic community behaved like the natural one and was therefore representative of the latter in regard to carbon source consumption. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  9. Aerobic Degradation of 2,4,6-Trinitrotoluene by Enterobacter cloacae PB2 and by Pentaerythritol Tetranitrate Reductase

    PubMed Central

    French, Christopher E.; Nicklin, Stephen; Bruce, Neil C.

    1998-01-01

    Enterobacter cloacae PB2 was originally isolated on the basis of its ability to utilize nitrate esters, such as pentaerythritol tetranitrate (PETN) and glycerol trinitrate, as the sole nitrogen source for growth. The enzyme responsible is an NADPH-dependent reductase designated PETN reductase. E. cloacae PB2 was found to be capable of slow aerobic growth with 2,4,6-trinitrotoluene (TNT) as the sole nitrogen source. Dinitrotoluenes were not produced and could not be used as nitrogen sources. Purified PETN reductase was found to reduce TNT to its hydride-Meisenheimer complex, which was further reduced to the dihydride-Meisenheimer complex. Purified PETN reductase and recombinant Escherichia coli expressing PETN reductase were able to liberate nitrogen as nitrite from TNT. The ability to remove nitrogen from TNT suggests that PB2 or recombinant organisms expressing PETN reductase may be useful for bioremediation of TNT-contaminated soil and water. PMID:9687442

  10. Microbial recycling of glycerol to biodiesel.

    PubMed

    Yang, Liu; Zhu, Zhi; Wang, Weihua; Lu, Xuefeng

    2013-12-01

    The sustainable supply of lipids is the bottleneck for current biodiesel production. Here microbial recycling of glycerol, byproduct of biodiesel production to biodiesel in engineered Escherichia coli strains was reported. The KC3 strain with capability of producing fatty acid ethyl esters (FAEEs) from glucose was used as a starting strain to optimize fermentation conditions when using glycerol as sole carbon source. The YL15 strain overexpressing double copies of atfA gene displayed 1.7-fold increase of FAEE productivity compared to the KC3 strain. The titer of FAEE in YL15 strain reached to 813 mg L(-1) in minimum medium using glycerol as sole carbon source under optimized fermentation conditions. The titer of glycerol-based FAEE production can be significantly increased by both genetic modifications and fermentation optimization. Microbial recycling of glycerol to biodiesel expands carbon sources for biodiesel production. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Truth, models, model sets, AIC, and multimodel inference: a Bayesian perspective

    USGS Publications Warehouse

    Barker, Richard J.; Link, William A.

    2015-01-01

    Statistical inference begins with viewing data as realizations of stochastic processes. Mathematical models provide partial descriptions of these processes; inference is the process of using the data to obtain a more complete description of the stochastic processes. Wildlife and ecological scientists have become increasingly concerned with the conditional nature of model-based inference: what if the model is wrong? Over the last 2 decades, Akaike's Information Criterion (AIC) has been widely and increasingly used in wildlife statistics for 2 related purposes, first for model choice and second to quantify model uncertainty. We argue that for the second of these purposes, the Bayesian paradigm provides the natural framework for describing uncertainty associated with model choice and provides the most easily communicated basis for model weighting. Moreover, Bayesian arguments provide the sole justification for interpreting model weights (including AIC weights) as coherent (mathematically self consistent) model probabilities. This interpretation requires treating the model as an exact description of the data-generating mechanism. We discuss the implications of this assumption, and conclude that more emphasis is needed on model checking to provide confidence in the quality of inference.

  12. Risk assessment instruments in clinical practice.

    PubMed

    Côté, Gilles; Crocker, Anne G; Nicholls, Tonia L; Seto, Michael C

    2012-04-01

    To determine whether the items in one of the most widely validated instruments of violence risk assessment, the Historical-Clinical-Risk Management-20 (HCR-20), are used in review board hearings to assess the risk of violence by people found Not Criminally Responsible on account of Mental Disorder (NCRMD). This study was conducted from October 2004 to August 2006 in Quebec's sole forensic psychiatric hospital and 2 large civil psychiatric hospitals designated for the care of people declared NCRMD in the Montreal metropolitan area. The risk assessments presented by clinicians at annual review board hearings and the boards' rationale for the release or detention of people found NCRMD were contrasted with the risk assessments conducted by the research team using the HCR-20. The final sample was comprised of 96 men. Very few of the risk factors identified by prior research (HCR-20 items) were mentioned in the hearing process, whether in clinical reports, discussions during the hearing, or in the disposition justification. The findings confirm that there remains a significant gap between research evidence and risk assessment practice.

  13. The rights of man and animal experimentation.

    PubMed Central

    Martin, J

    1990-01-01

    Since emotions give contradictory signals about animal experimentation in medical science, man's relationship to animals must be based upon reason. Thomas Aquinas argues that man is essentially different from animals because man's intellectual processes show evidence of an abstract mechanism not possessed by animals. Man's rights arise in association with this essential difference. The consequence is that only man possesses true rights by Aquinas's definition; animals have them only by analogy. However, cruelty to animals is illicit and they should be protected, principally not because they have rights, but because he who is cruel to animals is more likely to be cruel to his fellowman. If there is a need for animal experimentation in science for the good of man, this approach gives philosophical justification for experimentation, since man's well-being must come before that of animals because of his unique possession of rights. However, those experiments should be carried out in the kindest way possible, to promote kindness towards man. To see man as solely part of a biological continuum in competition for rights with those beings close to him biologically, detracts from man's dignity. PMID:2135948

  14. Production of ligninolytic enzymes and some diffusible antifungal compounds by white-rot fungi using potato solid wastes as the sole nutrient source.

    PubMed

    Schalchli, H; Hormazábal, E; Rubilar, O; Briceño, G; Mutis, A; Zocolo, G J; Diez, M C

    2017-10-01

    The aim of this study was to evaluate the synthesis of ligninolytic enzymes and some diffusible antifungal compounds by white-rot fungi (WRF) using peels or discarded potato as the sole nutrient source. The strain Trametes hirsuta Ru-513 highlighted for its laccase activity (595 ± 33 U l -1 ), which is able to decolourize 87% of an anthraquinone dye using potato peels as the sole nutritional support. A native polyacrylamide gel of laccase proteins showed the presence of two isoenzymes, corresponding to proteins of 56 and 67 kDa, which were detected by SDS-PAGE. The antifungal activity of ethyl acetate extracts was evaluated by the agar diffusion method, where Anthracophyllum discolor Sp4 and Inonotus sp. Sp2 showed the highest inhibition zones of Mucor miehei. The fungal extracts also inhibited Fusarium oxysporum and Botrytis cinerea growth, with inhibition zones of up to 18 mm. The extract with the highest antifungal activity, from A. discolor Sp4 grown in discarded potato medium, was analysed using a gas chromatograph coupled to a mass spectrometer. Among the identified compounds, chlorinated aromatic compounds and veratryl alcohol were the most abundant compounds. The results revealed the relevance of potato waste valorization for the sustainable production of ligninolytic enzymes and antifungal compounds. This study reports the synthesis of ligninolytic enzymes and diffusible antifungal compounds by WRF using potato wastes as the sole nutrient source and suggests a relationship between the enzymatic activity and the synthesis of antifungal compounds. These compounds and the synthesis of halogen compounds by WRF using agro-industrial wastes have been poorly studied before. © 2017 The Society for Applied Microbiology.

  15. Stripped of illusions? Exploring system justification processes in capitalist and post-Communist societies.

    PubMed

    Cichocka, Aleksandra; Jost, John T

    2014-02-01

    Sociologists and political scientists have often observed that citizens of Central and Eastern Europe express high levels of disillusionment with their social, economic and political systems, in comparison with citizens of Western capitalist societies. In this review, we analyze system legitimation and delegitimation in post-Communist societies from a social psychological perspective. We draw on system justification theory, which seeks to understand how, when and why people do (and do not) defend, bolster and justify existing social systems. We review some of the major tenets and findings of the theory and compare research on system-justifying beliefs and ideologies in traditionally Capitalist and post-Communist countries to determine: (1) whether there are robust differences in the degree of system justification in post-Communist and Capitalist societies, and (2) the extent to which hypotheses derived from system justification theory receive support in the post-Communist context. To this end, we summarize research findings from over 20 countries and cite previously unpublished data from a public opinion survey conducted in Poland. Our analysis confirms that there are lower levels of system justification in post-Communist countries. At the same time, we find that system justification possesses similar social and psychological antecedents, manifestations and consequences in the two types of societies. We offer potential explanations for these somewhat complicated patterns of results and conclude by addressing implications for theory and research on system justification and system change (or transition). © 2013 International Union of Psychological Science.

  16. 46 CFR 112.25-10 - Transfer of emergency loads.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-10 Transfer of emergency loads. (a) When...

  17. 46 CFR 112.25-10 - Transfer of emergency loads.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-10 Transfer of emergency loads. (a) When...

  18. 46 CFR 112.25-10 - Transfer of emergency loads.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-10 Transfer of emergency loads. (a) When...

  19. 46 CFR 112.25-10 - Transfer of emergency loads.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-10 Transfer of emergency loads. (a) When...

  20. 46 CFR 112.25-10 - Transfer of emergency loads.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatic Starting Diesel Engine or Gas Turbine Driven Emergency Power Source as the Sole Emergency Power Source § 112.25-10 Transfer of emergency loads. (a) When...

  1. 40 CFR 144.86 - What are the definitions I need to know?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... of ground water protection areas are identified. (g) Other sensitive ground water areas. States may... to protecting underground sources of drinking water from contamination. These other sensitive ground water areas may include areas such as areas overlying sole-source aquifers; highly productive aquifers...

  2. 40 CFR 144.86 - What are the definitions I need to know?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of ground water protection areas are identified. (g) Other sensitive ground water areas. States may... to protecting underground sources of drinking water from contamination. These other sensitive ground water areas may include areas such as areas overlying sole-source aquifers; highly productive aquifers...

  3. 40 CFR 144.86 - What are the definitions I need to know?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of ground water protection areas are identified. (g) Other sensitive ground water areas. States may... to protecting underground sources of drinking water from contamination. These other sensitive ground water areas may include areas such as areas overlying sole-source aquifers; highly productive aquifers...

  4. 40 CFR 144.86 - What are the definitions I need to know?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of ground water protection areas are identified. (g) Other sensitive ground water areas. States may... to protecting underground sources of drinking water from contamination. These other sensitive ground water areas may include areas such as areas overlying sole-source aquifers; highly productive aquifers...

  5. Microbial utilization of electrically reduced neutral red as the sole electron donor for growth and metabolite production

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Park, D.H.; Laivenieks, M.; Guettler, M.V.

    1999-07-01

    Electrically reduced neutral red (NR) served as the sole source of reducing power for growth and metabolism of pure and mixed cultures of H[sub 2]-consuming bacteria in a novel electrochemical bioreactor system. NR was continuously reduced by the cathodic potential ([minus]1.5 V) generated from an electric current (0.3 to 1.0 mA), and it was subsequently oxidized by Actinobacillus succinogenes or by mixed methanogenic cultures. The A. succinogenes mutant strain FZ-6 did not grow on fumarate alone unless electrically reduced NR or hydrogen was present as the electron donor for succinate production. The mutant strain, unlike the wild type, lacked pyruvatemore » formate lyase and formate dehydrogenase. Electrically reduced NR also replaced hydrogen as the sole electron donor source for growth and production of methane from CO[sub 2]. These results show that both pure and mixed cultures can function as electrochemical devices when electrically generated reducing power can be used to drive metabolism. The potential utility of utilizing electrical reducing power in enhancing industrial fermentations or biotransformation processes is discussed.« less

  6. Inducing Attitude Change toward Online Gaming among Adolescent Players Based on Dissonance Theory: The Role of Threats and Justification of Effort

    ERIC Educational Resources Information Center

    Wan, Chin-Sheng; Chiou, Wen-Bin

    2010-01-01

    The negative impact of online gaming on adolescents has received much attention. The question of how to reduce their pathological use of online gaming is a critical issue. Based on the concept of external justification in dissonance theory, this experimental study aimed to examine whether severity of threat and justification of effort would impact…

  7. Case study: molasses as the primary energy source on an organic grazing dairy

    USDA-ARS?s Scientific Manuscript database

    Organic dairies face many challenges, one of which is the high cost of purchased organic grains. Molasses may be a less expensive energy alternative. However, anecdotal results have been mixed for farms that used molasses as the sole energy source. This research project quantified animal performance...

  8. Evaluation of a Sustainable Remediation Option: Beneficial Reuse of Petroleum-Contaminated Sediment as an Energy Source

    EPA Science Inventory

    The characteristics of petroleum-contaminated sediment (PCS) have been evaluated to assess whether the practice of its beneficial reuse as a sole or supplemental energy source is sustainable relative to other sediment remediation options such as monitored natural recovery (MNR), ...

  9. 40 CFR 256.50 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... underground sources of drinking water under the authority of section 1442(a)(8)(C) of the Safe Drinking Water... Drinking Water Act (42 U.S.C. 300f et seq.) and with the designation of sole source aquifers under section... recovery and solid waste disposal programs at various installations); (8) Department of Energy (State...

  10. 40 CFR 256.50 - Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... underground sources of drinking water under the authority of section 1442(a)(8)(C) of the Safe Drinking Water... Drinking Water Act (42 U.S.C. 300f et seq.) and with the designation of sole source aquifers under section... recovery and solid waste disposal programs at various installations); (8) Department of Energy (State...

  11. 40 CFR 256.50 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... underground sources of drinking water under the authority of section 1442(a)(8)(C) of the Safe Drinking Water... Drinking Water Act (42 U.S.C. 300f et seq.) and with the designation of sole source aquifers under section... recovery and solid waste disposal programs at various installations); (8) Department of Energy (State...

  12. 40 CFR 256.50 - Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... underground sources of drinking water under the authority of section 1442(a)(8)(C) of the Safe Drinking Water... Drinking Water Act (42 U.S.C. 300f et seq.) and with the designation of sole source aquifers under section... recovery and solid waste disposal programs at various installations); (8) Department of Energy (State...

  13. 40 CFR 256.50 - Requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... underground sources of drinking water under the authority of section 1442(a)(8)(C) of the Safe Drinking Water... Drinking Water Act (42 U.S.C. 300f et seq.) and with the designation of sole source aquifers under section... recovery and solid waste disposal programs at various installations); (8) Department of Energy (State...

  14. 48 CFR 1306.302-5 - Authorized or required by statute.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 1306.302-5 Authorized or required by statute. In accordance with Executive Order 13457, a sole source acquisition may not be justified on the basis of any earmark included in any non-statutory source, except when...

  15. BOOK REVIEW OF "ASSESSMENT AND CONTROL OF NONPOINT SOURCE POLLUTION OF AQUATIC ECOSYSTEMS: A PRACTICAL APPROACH"

    EPA Science Inventory

    This book is geared to environmental specialists and planners, heavy on the technical side. It goes beyond tranditional nonpoint source (NPS) approaches which typically only look at stormwater as athe sole NPS pollution driver. There is some overreaching material beyond the conte...

  16. Multiple Sources of Prescription Payment and Risky Opioid Therapy Among Veterans.

    PubMed

    Becker, William C; Fenton, Brenda T; Brandt, Cynthia A; Doyle, Erin L; Francis, Joseph; Goulet, Joseph L; Moore, Brent A; Torrise, Virginia; Kerns, Robert D; Kreiner, Peter W

    2017-07-01

    Opioid overdose and other related harms are a major source of morbidity and mortality among US Veterans, in part due to high-risk opioid prescribing. We sought to determine whether having multiple sources of payment for opioids-as a marker for out-of-system access-is associated with risky opioid therapy among veterans. Cross-sectional study examining the association between multiple sources of payment and risky opioid therapy among all individuals with Veterans Health Administration (VHA) payment for opioid analgesic prescriptions in Kentucky during fiscal year 2014-2015. Source of payment categories: (1) VHA only source of payment (sole source); (2) sources of payment were VHA and at least 1 cash payment [VHA+cash payment(s)] whether or not there was a third source of payment; and (3) at least one other noncash source: Medicare, Medicaid, or private insurance [VHA+noncash source(s)]. Our outcomes were 2 risky opioid therapies: combination opioid/benzodiazepine therapy and high-dose opioid therapy, defined as morphine equivalent daily dose ≥90 mg. Of the 14,795 individuals in the analytic sample, there were 81.9% in the sole source category, 6.6% in the VHA+cash payment(s) category, and 11.5% in the VHA+noncash source(s) category. In logistic regression, controlling for age and sex, persons with multiple payment sources had significantly higher odds of each risky opioid therapy, with those in the VHA+cash having significantly higher odds than those in the VHA+noncash source(s) group. Prescribers should examine the prescription monitoring program as multiple payment sources increase the odds of risky opioid therapy.

  17. Sexual Assault Perpetrators’ Justifications for Their Actions: Relationships to Rape Supportive Attitudes, Incident Characteristics, and Future Perpetration

    PubMed Central

    Wegner, Rhiana; Abbey, Antonia; Pierce, Jennifer; Pegram, Sheri E.; Woerner, Jacqueline

    2015-01-01

    Perpetrators use rape supportive attitudes and sexual assault incident characteristics to justify forcing sex on their victims. Perpetrators who can justify their behaviors are at increased risk for future perpetration. This study examined the relationships between rape supportive attitudes, sexual assault incident characteristics, and the post-assault justifications of 183 men sampled from the community who self-reported committing at least one act of sexual aggression. Hierarchical multiple regression analyses indicated that rape supportive attitudes, expectations for having sex, misperceptions of sexual intent, victims’ alcohol consumption, attempts to be alone with her, and the number of consensual sexual activities prior to the unwanted sex were significant predictors of perpetrators’ post-assault use of justifications. Greater use of justifications was a significant predictor of sexual aggression over a 1-year follow-up interval. These findings demonstrate the need for further research exploring when and why perpetrators use post-assault justifications and whether they are amenable to change. PMID:26056162

  18. Sexual Assault Perpetrators' Justifications for Their Actions: Relationships to Rape Supportive Attitudes, Incident Characteristics, and Future Perpetration.

    PubMed

    Wegner, Rhiana; Abbey, Antonia; Pierce, Jennifer; Pegram, Sheri E; Woerner, Jacqueline

    2015-08-01

    Perpetrators use rape supportive attitudes and sexual assault incident characteristics to justify forcing sex on their victims. Perpetrators who can justify their behaviors are at increased risk for future perpetration. This study examined the relationships between rape supportive attitudes, sexual assault incident characteristics, and the post-assault justifications of 183 men sampled from the community who self-reported committing at least one act of sexual aggression. Hierarchical multiple regression analyses indicated that rape supportive attitudes, expectations for having sex, misperceptions of sexual intent, victims' alcohol consumption, attempts to be alone with her, and the number of consensual sexual activities prior to the unwanted sex were significant predictors of perpetrators' post-assault use of justifications. Greater use of justifications was a significant predictor of sexual aggression over a 1-year follow-up interval. These findings demonstrate the need for further research exploring when and why perpetrators use post-assault justifications and whether they are amenable to change. © The Author(s) 2015.

  19. A system justification view of sexual violence: legitimizing gender inequality and reduced moral outrage are connected to greater rape myth acceptance.

    PubMed

    Chapleau, Kristine M; Oswald, Debra L

    2014-01-01

    Rape is a pervasive social problem that causes serious physical and psychological repercussions. Rape victims' recovery is often complicated by the public's failure to believe the victim and restore justice. This study applied system justification theory to examine whether the justification of gender inequality is related to moral outrage (an emotional precursor to corrective action) and rape myth acceptance; we also examined whether rape myth acceptance is associated with moral outrage at injustice. Results showed that gender-specific system justification correlated with less moral outrage at human suffering as well as greater rape myth acceptance. The relationships between these variables were similar for men and for women, a finding that suggests that rape myths are system justifying for women. When we controlled for gender-specific system justification, rape myth acceptance correlated with less moral outrage. Results are discussed in the context of how legitimizing ideologies reduce moral outrage at injustice and perpetuate a system of sexual violence.

  20. Effects of the Multiple Solutions and Question Prompts on Generalization and Justification for Non-Routine Mathematical Problem Solving in a Computer Game Context

    ERIC Educational Resources Information Center

    Lee, Chun-Yi; Chen, Ming-Jang; Chang, Wen-Long

    2014-01-01

    The aim of this study is to investigate the effects of solution methods and question prompts on generalization and justification of non-routine problem solving for Grade 9 students. The learning activities are based on the context of the frog jumping game. In addition, related computer tools were used to support generalization and justification of…

  1. Direct and indirect effects of parenting practices on socio-moral approval of aggression in Polish young adults. Do all practices matter?

    PubMed

    Dominiak-Kochanek, Monika; Konopka, Karolina; Rutkowska, Marta; Frączek, Adam; Ramirez, J Martin

    2018-06-01

    The purpose of this article was to determine the socialisation antecedents of socio-moral approval of aggression (SMAA). In Study 1, we assessed factorial structure and reliability of the SMAA with a sample of 355 students who reported on the extent to which they approved of six forms of aggressive behaviour and six justifications of aggression. Two-factor solutions were obtained with regard to forms and justifications of aggressive acts. Thus, approval of extreme and minor aggression was distinguished as well as legitimate and illegitimate justifications of aggression. In Study 2, we tested the path models of the socialisation antecedents that contributed to the high approval of minor and extreme aggressive acts as well as legitimate and illegitimate justifications of aggression. Data were collected from 173 undergraduate students. Path analyses showed that high levels of approval of extremely aggressive acts and of illegitimate justifications of aggression were preceded by a sequence of negative life events, beginning with frequent misbehaviour in childhood, corporal punishment used by parents and ending with delinquency in adolescence. The approval of minor aggression had little relation to socialisation factors apart from a detrimental effect of psychological aggression while approval of legitimate justifications of aggression had no socialisation antecedents. © 2016 International Union of Psychological Science.

  2. Guidelines as rationing tools: a qualitative analysis of psychosocial patient selection criteria for cardiac procedures

    PubMed Central

    Giacomini, Mita K.; Cook, Deborah J.; Streiner, David L.; Anand, Sonia S.

    2001-01-01

    Background Cardiac procedure guidelines often include psychosocial criteria for selecting patients that potentially introduce social value judgements into clinical decisions and decisions about the rationing of care. The aim of this study was to investigate the terms and justifications for and the meanings of psychosocial patient characteristics used in cardiac procedure guidelines. Methods We selected English-language guidelines published since 1990 and chapters in textbooks published since 1989. These guidelines amalgamated multiple sources of evidence and expertise and made recommendations regarding patient selection for specific procedures. A multidisciplinary team of physicians and social scientists extracted passages regarding psychosocial criteria and developed categories and conceptual relationships to describe and interpret their content. Results Sixty-five papers met the criteria for inclusion in the study. Forty-five (69%) mentioned psychosocial criteria as procedure indications or contraindications. The latter fell into several categories, including behavioural and psychological issues, relationships with significant others, financial resources, social roles and environmental circumstances. Interpretation Psychosocial characteristics are portrayed as having 2 roles in patient selection: as risk factors intrinsic to the candidate or as indicators of need for special intervention. Guidelines typically simply list psychosocial contraindications without clarifying their specific nature or providing any justification for their use. Psychosocial considerations can help in the evaluation of patients for cardiac procedures, but they become ethically controversial when used to restrict access. The use of psychosocial indications and contraindications could be improved by more precise descriptions of the psychosocial problem at issue, explanations regarding why the criterion matters and justification of the characteristic using a biological rationale or research evidence. PMID:11258209

  3. FIBER OPTICS: Theoretical basis of the method for reducing drift of the zero level of the output signal of a fiber-optic gyroscope with the aid of a Lyot depolarizer

    NASA Astrophysics Data System (ADS)

    Alekseev, É. I.; Bazarov, E. N.

    1992-09-01

    A theoretical justification is given of the widely used method of stabilization of the output signal from a fiber-optic gyroscope with a broad-band radiation source by a Lyot depolarizer. Different variants of including a depolarizer in such a gyroscope are considered and the role of the dichroism and birefringence induced in the gyroscope system is discussed.

  4. Calculated Research on the Energetic Characteristic of TN in Composite Solid Propellant,

    DTIC Science & Technology

    1986-01-06

    TEST CHART NATK)AAL BIREAU Of SIANDARN D %3 A F..• ,*’" ..... . . . L,.•...... . . . . . . . . FTD-ID(RS)T-0905-85 (0 FOREIGN TECHNOLOGY DIVISION...English pages: 12 Source: Yuhang Xuebao, Nr. 2, 1984, pp. 84-90 Country of origin: China Translated by: SCITRAN F33657-84- D -0165 Requester: FTD/TQTA...best quality copy available. Accesston 7i VTIS GT A&l DTIC TAB justif i,,Lltion- Distr-ibution/ Availability Codes Avail and/or D i t Special ft

  5. Clinically Unjustified Diagnostic Imaging – a Worrisome Tendency in Today’s Medical Practice

    PubMed Central

    Sobiecka, Aleksandra; Bekiesińska-Figatowska, Monika; Rutkowska, Milena; Latos, Tomasz; Walecki, Jerzy

    2016-01-01

    Summary Background The purpose of the study was to evaluate the percentage of unjustified examinations among all the CT and MRI studies performed by two radiology departments and to determine the types of examinations which are most commonly carried out unnecessarily. Material/Methods Three radiologists assessed the justification of CT and MRI examinations performed during a period of 14 days based on the referrals. The radiologists assessed 799 referrals for CT scans (847 examinations of a particular part of the body) and 269 MRI referrals (269 examinations). The criteria for justification were: medical expertise and the guidelines. During the first stage radiologists divided the examinations into 3 groups: justified, unjustified and the examinations of questionable justification. The second step was to determine the reasons why the studies were considered as unjustified or of questionable justification. Results 73 of 1116 examinations (6.54%) were considered to be unjustified or of a questionable justification. There were 59 CT scans (59/847=6.97%) and 14 MRI studies (14/269=5.20%). The most common reasons to consider them as unjustified or of questionable justification were: inadequate method of diagnostic imaging chosen as a first-line tool and lacking or insufficient clinical details. Conclusions In our investigation 6.54% of both CT and MRI examinations were considered as unjustified or of questionable justification, which is lower than described in other studies (from 7% to 26%). The assessment was based only on referrals, therefore a total share of these examinations is likely to be higher. PMID:27471577

  6. When and Why Is Religious Attendance Associated With Antigay Bias and Gay Rights Opposition? A Justification-Suppression Model Approach.

    PubMed

    Hoffarth, Mark Romeo; Hodson, Gordon; Molnar, Danielle S

    2017-04-24

    Even in relatively tolerant countries, antigay bias remains socially divisive, despite being widely viewed as violating social norms of tolerance. From a Justification-Suppression Model (JSM) framework, social norms may generally suppress antigay bias in tolerant countries, yet be "released" by religious justifications among those who resist gay rights progress. Across large, nationally representative US samples (Study 1) and international samples (Study 2, representing a total of 97 different countries), over 215,000 participants, and various indicators of antigay bias (e.g., dislike, moral condemnation, opposing gay rights), individual differences in religious attendance was uniquely associated with greater antigay bias, over and above religious fundamentalism, political ideology, and religious denomination. Moreover, in 4 of 6 multilevel models, religious attendance was associated with antigay bias in countries with greater gay rights recognition, but was unrelated to antigay bias in countries with lower gay rights recognition (Study 2). In Study 3, Google searches for a religious justification ("love the sinner hate the sin") coincided temporally with gay-rights relevant searches. In U.S. (Study 4) and Canadian (Study 5) samples, much of the association between religious attendance and antigay bias was explained by "sinner-sin" religious justification, with religious attendance not associated with antigay bias when respondents reported relatively low familiarity with this justification (Study 5). These findings suggest that social divisions on homosexuality in relatively tolerant social contexts may be in large part due to religious justifications for antigay bias (consistent with the JSM), with important implications for decreasing bias. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  7. The integration of claims to health-care: a programming approach.

    PubMed

    Anand, Paul

    2003-09-01

    The paper contributes to the use of social choice and welfare theory in health economics by developing and applying the integration of claims framework to health-care rationing. Related to Sen's critique of neo-classical welfare economics, the integration of claims framework recognises three primitive sources of claim: consequences, deontology and procedures. A taxonomy is presented with the aid of which it is shown that social welfare functions reflecting these claims individually or together, can be specified. Some of the resulting social choice rules can be regarded as generalisations of health-maximisation and all have normative justifications, though the justifications may not be universally acceptable. The paper shows how non-linear programming can be used to operationalise such choice rules and illustrates their differential impacts on the optimal provision of health-care. Following discussion of relations to the capabilities framework and the context in which rationing occurs, the paper concludes that the integration of claims provides a viable framework for modelling health-care rationing that is technically rigorous, general and tractable, as well as being consistent with relevant moral considerations and citizen preferences.

  8. Degradation and mineralization of atrazine by a soil bacterial isolate.

    PubMed Central

    Radosevich, M; Traina, S J; Hao, Y L; Tuovinen, O H

    1995-01-01

    An atrazine-degrading bacterial culture was isolated from an agricultural soil previously impacted by herbicide spills. The organism was capable of using atrazine under aerobic conditions as the sole source of C and N. Cyanuric acid could replace atrazine as the sole source of N, indicating that the organism was capable of ring cleavage. Ring cleavage was confirmed in 14CO2 evolution experiments with [U-14C-ring]atrazine. Between 40 and 50% of ring-14C was mineralized to 14CO2. [14C]biuret and [14C]urea were detected in spent culture media. Cellular assimilation of 14C was negligible, in keeping with the fully oxidized valence of the ring carbon. Chloride release was stoichiometric. The formation of ammonium during atrazine degradation was below the stoichiometric amount, suggesting a deficit due to cellular assimilation and metabolite-N accumulation. With excess glucose and with atrazine as the sole N source, free ammonium was not detected, suggesting assimilation into biomass. The organism degraded atrazine anaerobically in media which contained (i) atrazine only, (ii) atrazine and glucose, and (iii) atrazine, glucose, and nitrate. To date, this is the first report of a pure bacterial isolate with the ability to cleave the s-triazine ring structure of atrazine. It was also concluded that this bacterium was capable of dealkylation, dechlorination, and deamination in addition to ring cleavage. PMID:7887609

  9. 48 CFR 1503.670 - Solicitation of disclosure provision.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts with Government Employees... Certification, in all solicitations for sole source acquisitions. [50 FR 14357, Apr. 11, 1985] ...

  10. From mirror self-recognition to the looking-glass self: exploring the Justification Hypothesis.

    PubMed

    Shaffer, Leigh S

    2005-01-01

    In his Tree of Knowledge (ToK) System, Henriques (2003) posits that the human ego or "self" has evolved because human beings are the only animals that have had to justify their behavior to others. This essay provides evidence for this Justification Hypothesis (JH) from everyday life sociology, starting with the work of George Herbert Mead and Charles Horton Cooley, and focuses on research related to the concept of the "looking-glass self." Special emphasis is given to the pragmatics of speech acts, the presentation of self in interaction rituals, the accounts given by actors in justification of their actions, and the role of social norms and conformity in the large-scale justification systems commonly called "culture."

  11. Justification of violence beliefs and social problem-solving as mediators between maltreatment and behavior problems in adolescents.

    PubMed

    Calvete, Esther

    2007-05-01

    This study examined whether justification of violence beliefs and social problem solving mediated between maltreatment experiences and aggressive and delinquent behavior in adolescents. Data were collected on 191 maltreated and 546 nonmaltreated adolescents (ages 14 to 17 years), who completed measures of justification of violence beliefs, social problem-solving dimensions (problem orientation, and impulsivity/carelessness style), and psychological problems. Findings indicated that maltreated adolescents' higher levels of delinquent and aggressive behavior were partially accounted for by justification of violence beliefs, and that their higher levels of depressive symptoms were partially mediated by a more negative orientation to social problem-solving. Comparisons between boys and girls indicated that the model linking maltreatment, cognitive variables, and psychological problems was invariant.

  12. Influence of electron donors and copper concentration on geochemical and mineralogical processes under conditions of biological sulphate reduction

    NASA Astrophysics Data System (ADS)

    Wolicka, Dorota; Borkowski, Andrzej

    2014-03-01

    Sulphidogenous microorganism communities were isolated from soil polluted by crude oil. The study was focused on determining the influence of 1) copper (II) concentration on the activity of selected microorganism communities and 2) the applied electron donor on the course and evolution of mineral-forming processes under conditions favouring growth of sulphate-reducing bacteria (SRB). The influence of copper concentration on the activity of selected microorganism communities and the type of mineral phases formed was determined during experiments in which copper (II) chloride at concentrations of 0.1, 0.2, 0.5 and 0.7 g/L was added to SRB cultures. The experiments were performed in two variants: with ethanol (4 g/L) or lactate (4 g/L) as the sole carbon source. In order to determine the taxonomic composition of the selected microorganism communities, the 16S rRNA method was used. Results of this analysis confirmed the presence of Desulfovibrio, Desulfohalobium, Desulfotalea, Thermotoga, Solibacter, Gramella, Anaeromyxobacter and Myxococcus sp. in the stationary cultures. The post-culture sediments contained covelline (CuS) and digenite (Cu9S5 ). Based on the results, it can be stated that the type of carbon source applied during incubation plays a crucial role in determining the mineral composition of the post-culture sediments. Thus, regardless of the amount of copper ion introduced to a culture with lactate as the sole carbon source, no copper sulphide was observed in the post-culture sediments. Cultures with ethanol as the sole carbon source, on the other hand, yielded covelline or digenite in all post-culture sediments.

  13. Methanol Metabolism in Pseudomonad C

    PubMed Central

    Stieglitz, B.; Mateles, R. I.

    1973-01-01

    Cell suspensions of pseudomonad C, a bacterium capable of growth on methanol as sole carbon source, were able to oxidize methanol, formaldehyde, and formate, although the rates of oxidation for the latter two compounds were much slower. The latter compounds also could not serve as sole carbon sources. Through the use of labeled compounds, it was shown that in the presence of methanol, formaldehyde, formate, and bicarbonate were incorporated into trichloroacetic acid-precipitable material. Hexose phosphate synthetase activity was found, indicating the assimilation of methanol via an allulose pathway. No hydroxypyruvate reductase activity was found, nor was any complex membrane structure observed. Such a combination of characteristics has been observed in an obligate methylotroph (Pseudomonas W1), but pseudomonad C can utilize a variety of non-methyl substrates. Images PMID:4349032

  14. 15 CFR 930.42 - Public participation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) Specify a source for additional information, e.g., a State agency web site; and (4) Specify a contact for... sites. However, electronic notices, e.g., web sites, shall not be the sole source of a public notification, but may be used in conjunction with other means. Web sites may be used to provide a location for...

  15. Cyclic variations in nitrogen uptake rate of soybean plants: ammonium as a nitrogen source

    NASA Technical Reports Server (NTRS)

    Henry, L. T.; Raper, C. D. Jr

    1989-01-01

    When NO3- is the sole nitrogen source in flowing solution culture, the net rate of nitrogen uptake by nonnodulated soybean (Glycine max L. Merr. cv Ransom) plants cycles between maxima and minima with a periodicity of oscillation that corresponds with the interval of leaf emergence. Since soybean plants accumulate similar quantities of nitrogen when either NH4+ or NO3- is the sole source in solution culture controlled at pH 6.0, an experiment was conducted to determine if the oscillations in net rate of nitrogen uptake also occur when NH4+ is the nitrogen source. During a 21-day period of vegetative development, net uptake of NH4+ was measured daily by ion chromatography as depletion of NH4+ from a replenished nutrient solution containing 1.0 millimolar NH4+. The net rate of NH4+ uptake oscillated with a periodicity that was similar to the interval of leaf emergence. Instances of negative net rates of uptake indicate that the transition between maxima and minima involved changes in influx and efflux components of net NH4+ uptake.

  16. Utilization of 2,6-diaminopurine by Salmonella typhimurium.

    PubMed Central

    Garber, B B; Gots, J S

    1980-01-01

    The pathway for the utilization of 2,6-diaminopurine (DAP) as an exogenous purine source in Salmonella typhimurium was examined. In strains able to use DAP as a purine source, mutant derivatives lacking either purine nucleoside phosphorylase or adenosine deaminase activity lost the ability to do so. The implied pathway of DAP utilization was via its conversion to DAP ribonucleoside by purine nucleoside phosphorylase, followed by deamination to guanosine by adenosine deaminase. Guanosine can then enter the established purine salvage pathways. In the course of defining this pathway, purine auxotrophs able to utilize DAP as sole purine source were isolated and partially characterized. These mutants fell into several classes, including (i) strains that only required an exogenous source of guanine nucleotides (e.g., guaA and guaB strains); (ii) strains that had a purF genetic lesion (i.e., were defective in alpha-5-phosphoribosyl 1-pyrophosphate amidotransferase activity); and (iii) strains that had constitutive levels of purine nucleoside phosphorylase. Selection among purine auxotrophs blocked in the de novo synthesis of inosine 5'-monophosphate, for efficient growth on DAP as sole source of purine nucleotides, readily yielded mutants which were defective in the regulation of their deoxyribonucleoside-catabolizing enzymes (e.g., deoR mutants). PMID:6782081

  17. The Importance and Justifications for Astronomy Teaching: A Look at the Researches on the Area

    NASA Astrophysics Data System (ADS)

    Soler, D. R.; Leite, C.

    2013-08-01

    Many researchers in Astronomy Teaching often refer to Astronomy as an object of great curiosity. In this paper, we will present a survey concerning the importance and justifications researchers have given to Astronomy Teaching. In a universe of 180 papers about Astronomy Teaching, found in periodicals from the areas of Science, Physics and Astronomy Teaching in the last decade, in 29 of them, discussions about the importance or justifications to Astronomy Teaching were found. As the main result of this work, all the elements related to the importance and the justification for the Astronomy Teaching were organized and grouped in four categories of analysis, which indicate the nature of the justifications presented by the authors: Awakening of feelings and curiosities; Socio-historic-cultural relevance; World view and awareness expansion and Interdisciplinarity. In each category, related elements were grouped. By doing so, we could produce an articulation among the elements taken from different papers, matching them in a way that enabled us to obtain new inferences not individually present in any of the papers. Furthermore, when all the research was analyzed, it was also revealed that there were no papers that aimed at the investigation of the importance and justifications for Astronomy Teaching. It was still noticed that, in general, when researchers invoke the interdisciplinary character of Astronomy, they make it superficially. Since the researches do not show how they get the idea presented to the justifications for teaching Astronomy, some questions could have surfaced, such as: would it be possible to exist a kind of “common sense” for teaching and disseminating Astronomy that would make researchers understand Astronomy as a differential science? Would the "born interest" in Astronomy - pointed by some people - be something real? Does Astronomy really differ from other sciences?

  18. Complementary and alternative medicine: the challenges of ethical justification. A philosophical analysis and evaluation of ethical reasons for the offer, use and promotion of complementary and alternative medicine.

    PubMed

    Mertz, Marcel

    2007-09-01

    With the prevalence of complementary and alternative medicine (CAM) increasing in western societies, questions of the ethical justification of these alternative health care approaches and practices have to be addressed. In order to evaluate philosophical reasoning on this subject, it is of paramount importance to identify and analyse possible arguments for the ethical justification of CAM considering contemporary biomedical ethics as well as more fundamental philosophical aspects. Moreover, it is vital to provide adequate analytical instruments for this task, such as separating 'CAM as belief system' and 'CAM as practice'. Findings show that beneficence and non-maleficence are central issues for an ethical justification of CAM as practice, while freedom of thought and religion are central to CAM as belief system. Many justification strategies have limitations and qualifications that have to be taken into account. Singularly descriptive premises in an argument often prove to be more problematic than universal ethical principles. Thus, non-ethical issues related to a general philosophical underpinning--e.g. epistemology, semantics, and ontology--are highly relevant for determining a justification strategy, especially when strong metaphysical assumptions are involved. Even if some values are shared with traditional biomedicine, axiological differences have to be considered as well. Further research should be done about specific CAM positions. These could be combined with applied qualitative social research methods.

  19. 48 CFR 5.202 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... contract action results from acceptance of a proposal under the Small Business Innovation Development Act... proposal and acceptance is based solely upon the unique capability of the source to perform the particular...

  20. 48 CFR 5.202 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... contract action results from acceptance of a proposal under the Small Business Innovation Development Act... proposal and acceptance is based solely upon the unique capability of the source to perform the particular...

  1. Ultimate justification: Wittgenstein and medical ethics.

    PubMed

    Hughes, J

    1995-02-01

    Decisions must be justified. In medical ethics various grounds are given to justify decisions, but ultimate justification seems illusory and little considered. The philosopher Wittgenstein discusses the problem of ultimate justification in the context of general philosophy. His comments, nevertheless, are pertinent to ethics. From a discussion of Wittgensteinian notions, such as 'bedrock', the idea that 'ultimate' justification is grounded in human nature as such is derived. This discussion is relevant to medical ethics in at least five ways: it shows generally what type of certainty there is in practical ethics; it seems to imply some objective foundation to our ethical judgements; it squares with our experience of making ethical decisions; it shows something of the nature of moral arguments; and, finally, it has implications for teaching medicine and ethics.

  2. Justifications and comparisons in the division of household labor: the relevance of gender ideology.

    PubMed

    Martínez, Carmen; Paterna, Consuelo; Yago, Carmen

    2010-05-01

    This study tests the direct relevance of justifications and social comparisons (predictors of perceptions of fairness) on different types of household labour distribution, and the importance of masculinity ideology and neosexism on these variables. The participants were heterosexual dual-earner couples. Our results showed that both men and women use more justifications when their housework distribution is not equal, but only women use social comparisons associated with the ways of distributing domestic work. In addition, we observe that, in both men and women, justifications are related to a traditional masculine ideology, but a different model appears in relation to comparisons which are associated with neosexism in men and with traditional masculine ideology in women. Implications and suggestions for future research are discussed.

  3. Competency criteria and the class inclusion task: modeling judgments and justifications.

    PubMed

    Thomas, H; Horton, J J

    1997-11-01

    Preschool age children's class inclusion task responses were modeled as mixtures of different probability distributions. The main idea: Different response strategies are equivalent to different probability distributions. A child displays cognitive strategy s if P (child uses strategy s, given the child's observed score X = x) = p(s) is the most probable strategy. The general approach is widely applicable to many settings. Both judgment and justification questions were asked. Judgment response strategies identified were subclass comparison, guessing, and inclusion logic. Children's justifications lagged their judgments in development. Although justification responses may be useful, C. J. Brainerd was largely correct: If a single response variable is to be selected, a judgments variable is likely the preferable one. But the process must be modeled to identify cognitive strategies, as B. Hodkin has demonstrated.

  4. Ultimate justification: Wittgenstein and medical ethics.

    PubMed Central

    Hughes, J

    1995-01-01

    Decisions must be justified. In medical ethics various grounds are given to justify decisions, but ultimate justification seems illusory and little considered. The philosopher Wittgenstein discusses the problem of ultimate justification in the context of general philosophy. His comments, nevertheless, are pertinent to ethics. From a discussion of Wittgensteinian notions, such as 'bedrock', the idea that 'ultimate' justification is grounded in human nature as such is derived. This discussion is relevant to medical ethics in at least five ways: it shows generally what type of certainty there is in practical ethics; it seems to imply some objective foundation to our ethical judgements; it squares with our experience of making ethical decisions; it shows something of the nature of moral arguments; and, finally, it has implications for teaching medicine and ethics. PMID:7776343

  5. Ammonium as sole N source improves grain quality in wheat.

    PubMed

    Fuertes-Mendizábal, Teresa; González-Torralba, Jon; Arregui, Luis M; González-Murua, Carmen; González-Moro, M Begoña; Estavillo, José M

    2013-07-01

    The skilful handling of N fertilizer, including N source type and its timing, is necessary to obtain maximum profitability in wheat crops in terms of production and quality. Studies on grain yield and quality with ammonium as sole N source have not yet been conducted. The aim of this study was to evaluate the effect of N source management (nitrate vs. ammonium), and splitting it into two or three amendments during the wheat life cycle, on grain yield and quality under irrigated conditions. This experiment demonstrates that Cezanne wheat plants growing with ammonium as exclusive N source are able to achieve the same yield as plants growing with nitrate and that individual wheat plants grown in irrigated pots can efficiently use late N applied in GS37. Ammonium nutrition increased both types of grain reserve proteins (gliadins and glutenins) and also increased the ratio gli/glu with respect to nitrate nutrition. The splitting of the N rate enhanced the ammonium effect on grain protein composition. The application of ammonium N source, especially when split into three amendments, has an analogous effect on grain protein content and composition to applications at a higher N rate, leading to higher N use efficiency. © 2012 Society of Chemical Industry.

  6. Molecular characterization and analysis of the acrB gene of Aspergillus nidulans: a gene identified by genetic interaction as a component of the regulatory network that includes the CreB deubiquitination enzyme.

    PubMed Central

    Boase, Natasha A; Lockington, Robin A; Adams, Julian R J; Rodbourn, Louise; Kelly, Joan M

    2003-01-01

    Mutations in the acrB gene, which were originally selected through their resistance to acriflavine, also result in reduced growth on a range of sole carbon sources, including fructose, cellobiose, raffinose, and starch, and reduced utilization of omega-amino acids, including GABA and beta-alanine, as sole carbon and nitrogen sources. The acrB2 mutation suppresses the phenotypic effects of mutations in the creB gene that encodes a regulatory deubiquitinating enzyme, and in the creC gene that encodes a WD40-repeat-containing protein. Thus AcrB interacts with a regulatory network controlling carbon source utilization that involves ubiquitination and deubiquitination. The acrB gene was cloned and physically analyzed, and it encodes a novel protein that contains three putative transmembrane domains and a coiled-coil region. AcrB may play a role in the ubiquitination aspect of this regulatory network. PMID:12750323

  7. Constitutive cellulase production from glucose using the recombinant Trichoderma reesei strain overexpressing an artificial transcription activator.

    PubMed

    Zhang, Xiaoyue; Li, Yonghao; Zhao, Xinqing; Bai, Fengwu

    2017-01-01

    The high cost of cellulase production presents biggest challenge in biomass deconstruction. Cellulase production by Trichoderma reesei using low cost carbon source is of great interest. In this study, an artificial transcription activator containing the Cre1 binding domain linked to the Xyr1 effector and binding domains was designed and constitutively overexpressed in T. reesei RUT C30. The recombinant strain T. reesei zxy-2 displayed constitutive cellulase production using glucose as a sole carbon source, and the production titer was 12.75-fold of that observed with T. reesei RUT C30 in shake flask culture. Moreover, FPase and xylanase titers of 2.63 and 108.72IU/mL, respectively, were achieved using glucose as sole carbon source within 48h in a 7-L fermenter by batch fermentation using T. reesei zxy-2. The crude enzyme obtained was used to hydrolyze alkali pretreated corn stover, and a high glucose yield of 99.18% was achieved. Copyright © 2016. Published by Elsevier Ltd.

  8. Biodegradation of Polyester Polyurethane by Endophytic Fungi▿

    PubMed Central

    Russell, Jonathan R.; Huang, Jeffrey; Anand, Pria; Kucera, Kaury; Sandoval, Amanda G.; Dantzler, Kathleen W.; Hickman, DaShawn; Jee, Justin; Kimovec, Farrah M.; Koppstein, David; Marks, Daniel H.; Mittermiller, Paul A.; Núñez, Salvador Joel; Santiago, Marina; Townes, Maria A.; Vishnevetsky, Michael; Williams, Neely E.; Vargas, Mario Percy Núñez; Boulanger, Lori-Ann; Bascom-Slack, Carol; Strobel, Scott A.

    2011-01-01

    Bioremediation is an important approach to waste reduction that relies on biological processes to break down a variety of pollutants. This is made possible by the vast metabolic diversity of the microbial world. To explore this diversity for the breakdown of plastic, we screened several dozen endophytic fungi for their ability to degrade the synthetic polymer polyester polyurethane (PUR). Several organisms demonstrated the ability to efficiently degrade PUR in both solid and liquid suspensions. Particularly robust activity was observed among several isolates in the genus Pestalotiopsis, although it was not a universal feature of this genus. Two Pestalotiopsis microspora isolates were uniquely able to grow on PUR as the sole carbon source under both aerobic and anaerobic conditions. Molecular characterization of this activity suggests that a serine hydrolase is responsible for degradation of PUR. The broad distribution of activity observed and the unprecedented case of anaerobic growth using PUR as the sole carbon source suggest that endophytes are a promising source of biodiversity from which to screen for metabolic properties useful for bioremediation. PMID:21764951

  9. Aerobic degradation of 2,4,6-trinitrotoluene by Enterobacter cloacae PB2 and by pentaerythritol tetranitrate reductase

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    French, C.E.; Bruce, N.C.; Nicklin, S.

    1998-08-01

    Enterobacter cloacae PB2 was originally isolated on the basis of its ability to utilize nitrate esters, such as pentaerythritol tetranitrate (PETN) and glycerol trinitrate, as the sole nitrogen source for growth. The enzyme responsible is an NADPH-dependent reductase designated PETN reductase. E. cloacae PB2 was found to be capable of slow aerobic growth with 2,4,6-trinitrotoluene (TNT) as the sole nitrogen source. Dinitrotoluenes were not produced and could not be used as nitrogen sources. Purified PETN reductase was found to reduce TNT to its hydride-Meisenheimer complex, which was further reduced to the dihydride-Meisenheimer complex. Purified PETN reductase and recombinant Escherichia colimore » expressing PETN reductase were able to liberate nitrogen as nitrite from TNT. The ability to remove nitrogen from TNT suggests that PB2 or recombinant organisms expressing PETN reductase may be useful for bioremediation of TNT-contaminated soil and water.« less

  10. Biodegradation of polyester polyurethane by endophytic fungi.

    PubMed

    Russell, Jonathan R; Huang, Jeffrey; Anand, Pria; Kucera, Kaury; Sandoval, Amanda G; Dantzler, Kathleen W; Hickman, DaShawn; Jee, Justin; Kimovec, Farrah M; Koppstein, David; Marks, Daniel H; Mittermiller, Paul A; Núñez, Salvador Joel; Santiago, Marina; Townes, Maria A; Vishnevetsky, Michael; Williams, Neely E; Vargas, Mario Percy Núñez; Boulanger, Lori-Ann; Bascom-Slack, Carol; Strobel, Scott A

    2011-09-01

    Bioremediation is an important approach to waste reduction that relies on biological processes to break down a variety of pollutants. This is made possible by the vast metabolic diversity of the microbial world. To explore this diversity for the breakdown of plastic, we screened several dozen endophytic fungi for their ability to degrade the synthetic polymer polyester polyurethane (PUR). Several organisms demonstrated the ability to efficiently degrade PUR in both solid and liquid suspensions. Particularly robust activity was observed among several isolates in the genus Pestalotiopsis, although it was not a universal feature of this genus. Two Pestalotiopsis microspora isolates were uniquely able to grow on PUR as the sole carbon source under both aerobic and anaerobic conditions. Molecular characterization of this activity suggests that a serine hydrolase is responsible for degradation of PUR. The broad distribution of activity observed and the unprecedented case of anaerobic growth using PUR as the sole carbon source suggest that endophytes are a promising source of biodiversity from which to screen for metabolic properties useful for bioremediation.

  11. 21 CFR 520.2158a - Streptomycin sulfate oral solution.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... sole source of streptomycin. Warning: Certain strains of bacteria may develop a tolerance for...: Certain strains of bacteria may develop a tolerance for streptomycin. Consult a veterinarian or animal...

  12. 21 CFR 520.2158a - Streptomycin sulfate oral solution.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... sole source of streptomycin. Warning: Certain strains of bacteria may develop a tolerance for...: Certain strains of bacteria may develop a tolerance for streptomycin. Consult a veterinarian or animal...

  13. 21 CFR 522.2240 - Sulfaethoxypyridazine.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of respiratory infection (pneumonia, shipping fever), foot rot, calf scours; as adjunctive therapy in... sulfaethoxypyridazine; do not treat within 16 days of slaughter; as sole source of sulfonamide; milk that has been taken...

  14. 48 CFR 5.202 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Innovation Development Act of 1982 (Pub. L. 97-219); (8) The proposed contract action results from the... unsolicited research proposal and acceptance is based solely upon the unique capability of the source to...

  15. 48 CFR 5.202 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Innovation Development Act of 1982 (Pub. L. 97-219); (8) The proposed contract action results from the... unsolicited research proposal and acceptance is based solely upon the unique capability of the source to...

  16. Repeated-batch fermentations of xylose and glucose-xylose mixtures using a respiration-deficient Saccharomyces cerevisiae engineered for xylose metabolism.

    PubMed

    Kim, Soo Rin; Lee, Ki-Sung; Choi, Jin-Ho; Ha, Suk-Jin; Kweon, Dae-Hyuk; Seo, Jin-Ho; Jin, Yong-Su

    2010-11-01

    Xylose-fermenting Saccharomyces strains are needed for commercialization of ethanol production from lignocellulosic biomass. Engineered Saccharomyces cerevisiae strains expressing XYL1, XYL2 and XYL3 from Pichia stipitis, however, utilize xylose in an oxidative manner, which results in significantly lower ethanol yields from xylose as compared to glucose. As such, we hypothesized that reconfiguration of xylose metabolism from oxidative into fermentative manner might lead to efficient ethanol production from xylose. To this end, we generated a respiration-deficient (RD) mutant in order to enforce engineered S. cerevisiae to utilize xylose only through fermentative metabolic routes. Three different repeated-batch fermentations were performed to characterize characteristics of the respiration-deficient mutant. When fermenting glucose as a sole carbon source, the RD mutant exhibited near theoretical ethanol yields (0.46 g g(-1)) during repeated-batch fermentations by recycling the cells. As the repeated-batch fermentation progressed, the volumetric ethanol productivity increased (from 7.5 to 8.3 g L(-1)h(-1)) because of the increased biomass from previous cultures. On the contrary, the mutant showed decreasing volumetric ethanol productivities during the repeated-batch fermentations using xylose as sole carbon source (from 0.4 to 0.3 g L(-1)h(-1)). The mutant did not grow on xylose and lost fermenting ability gradually, indicating that the RD mutant cannot maintain a good fermenting ability on xylose as a sole carbon source. However, the RD mutant was capable of fermenting a mixture of glucose and xylose with stable yields (0.35 g g(-1)) and productivities (0.52 g L(-1)h(-1)) during the repeated-batch fermentation. In addition, ethanol yields from xylose during the mixed sugar fermentation (0.30 g g(-1)) were higher than ethanol yields from xylose as a sole carbon source (0.21 g g(-1)). These results suggest that a strategy for increasing ethanol yield through respiration-deficiency can be applied for the fermentation of lignocellulosic hydrolyzates containing glucose and xylose. Copyright © 2010 Elsevier B.V. All rights reserved.

  17. Justification and radiology: some ethical considerations.

    PubMed

    Sia, Santiago

    2009-07-01

    This paper, which seeks to address the issue of justification in radiology, intends firstly to comment on the current discussion of the ethical foundation of radiological practice that focuses on the move from utilitarianism to the rights-centred criterion. Secondly, and this constitutes the bulk of the paper, it aims to offer a philosophical perspective, which is hoped will lead to a consideration of certain specific areas in ethical decision-making in the attempts here to deal with the main issue of justification in radiology.

  18. Applying U.S. EOP Analytical Justification Experience for VVER Plants in the Ukraine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Linn, Paul A.; Julian, Harold V.; Chapman, James R.

    2002-07-01

    The foundation for new Emergency Operating Instructions (EOIs) being developed at several plants in the Ukraine is the Westinghouse Owners Group (WOG) Emergency Response Guidelines (ERGs) developed in the U.S. The ERGs were chosen as a base for the new EOIs for several reasons. First the overall structure and format was adaptable to VVER Pressurized Water Reactor (PWR) designs. Second, the ERGs have served as a base for many plant EOIs in both the U.S. and internationally. Third, key information supporting the ERGs was available. This paper describes the method used at one of the Ukrainian plants to provide anmore » analytical justification for their EOIs. The method being employed by a second plant is very similar, differing only slightly in how it is implemented. The WOG ERG development program, which started shortly after the accident at Three Mile Island Unit 2, used many sources of technical information on plant and system transient response, which were available in support of the plant design and licensing efforts. In addition, operating experience from many operating PWR plants in the U.S. and around the world was used. For example, design basis accident (DBA) analyses, documented in a plant's Safety Analysis Report (SAR) and other design documents, had been performed by Nuclear Steam Supply System (NSSS) vendors, utilities, or the Architect/Engineer. All relevant sources were considered in the development of the ERGs. Limited Probabilistic Risk Assessment (PRA) analyses were available during that time period. When a technical basis for a recovery strategy and associated operator actions was not available, an analysis was defined and performed. In general, these analyses were performed on a generic basis, and addressed the different categories of design (e.g., number of reactor coolant loops and/or low/high pressure safety injection system design). U.S. Nuclear Power plants that were in the WOG program were responsible for implementing the generic ERGs. This required the utilities to review the generic analyses to ensure that they were applicable and to justify any deviations from the ERG methodology. Modern PRA analyses are similar to the analyses supporting the ERGs since they address multiple failures and assume better estimate or expected assumptions for equipment availability and operator performance. The process being employed by Ukrainian plants is similar to the WOG. That is, available analyses and operating experience are being reviewed and pertinent information extracted to assist in the analytical justification of the EOIs. This includes the use of recently updated PRA and DBA analyses, other 'original' design information and operating experience. A systematic review of the EOIs is being conducted to identify items requiring analytical justification. For each analysis identified, the specific purpose of the analysis is being documented. The analysis needs are then compared to the available analyses and operating experience. From this review, new analyses needed to justify the EOIs are developed, and a basis for using existing analyses is established. The work is being conducted in two phases. The first phase performs all of the reviews and assessments necessary to determine the new analyses required to justify the EOIs. In the second phase, these new analyses will be conducted and documented, and the EOI Analytical Justification (AJ) report will be written. (authors)« less

  19. 31 CFR 539.504 - Departments and agencies of the United States Government.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... requirements under defense production agreements; intelligence requirements; sole source suppliers, spare parts... Office of Chemical, Biological and Missile Nonproliferation and the Office of the Assistant Legal Adviser...

  20. 31 CFR 539.504 - Departments and agencies of the United States Government.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... requirements under defense production agreements; intelligence requirements; sole source suppliers, spare parts... Office of Chemical, Biological and Missile Nonproliferation and the Office of the Assistant Legal Adviser...

  1. 31 CFR 539.504 - Departments and agencies of the United States Government.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... requirements under defense production agreements; intelligence requirements; sole source suppliers, spare parts... Office of Chemical, Biological and Missile Nonproliferation and the Office of the Assistant Legal Adviser...

  2. 31 CFR 539.504 - Departments and agencies of the United States Government.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... requirements under defense production agreements; intelligence requirements; sole source suppliers, spare parts... Office of Chemical, Biological and Missile Nonproliferation and the Office of the Assistant Legal Adviser...

  3. Wildlife

    Treesearch

    Norbert V. DeByle

    1985-01-01

    Aspen forests provide important habitat for many species of wildlife (Gullion 1977b), especially in the West (see the appendix to this chapter). In the coniferous forests of the interior West, aspen groves may be the only source of abundant forage; in the grasslands they may be the sole source of cover. A primary value of the aspen ecosystem in the West during the past...

  4. Effects of feeding hulled and hull-less barley with low- and high-forage diets on lactation performance, nutrient digestibility, and milk fatty acid composition of lactating dairy cows.

    PubMed

    Yang, Y; Ferreira, G; Teets, C L; Corl, B A; Thomason, W E; Griffey, C A

    2018-04-01

    The objective of this study was to evaluate lactation performance, nutrient digestibility, and milk fatty acid composition of high-producing dairy cows consuming diets containing hulled or hull-less barley as the grain source when feeding low-forage (LF) or high-forage (HF) diets. Eight primiparous (610 ± 40 kg of body weight and 72 ± 14 d in milk) and 16 multiparous (650 ± 58 kg of body weight and 58 ± 16 d in milk) Holstein cows were randomly assigned to 1 of 4 diets in a replicated 4 × 4 Latin square design with a 2 × 2 factorial arrangement of treatments and 21-d periods. Cows were assigned to squares based on parity (1, 2, and ≥3) and days in milk. Diets were formulated to contain on a dry matter basis (1) 45% forage and hulled barley as the sole grain source, (2) 65% forage and hulled barley as the sole grain source, (3) 45% forage and hull-less barley as the sole grain source, and (4) 65% forage and hull-less barley as the sole grain source. Dry matter intake tended to be lower for the diet with 65% forage and hulled barley than for the rest of the diets (24.4 vs. 26.6 kg/d). Neither the type of barley nor the forage-to-concentrate ratio affected milk yield (41.7 kg/d). Barley type did not affect milk fat or protein concentrations. Feeding LF diets decreased milk fat concentration from 3.91% to 3.50%. This decrease was less than anticipated and resulted in a 7% decrease in milk fat yield relative to cows consuming HF diets (1.60 and 1.49 kg/d for HF and LF diets, respectively). Feeding LF diets increased the concentration of C18:1 trans-10 in milk fat, suggesting that feeding LF diets may have marginally altered rumen function. In conclusion, LF diets containing barley grains can marginally decrease milk fat concentration. Overall, and based on the conditions of this study, there is limited evidence to anticipate a dramatic or acute milk fat depression when feeding hull-less barley as the grain source in diets for high-producing dairy cows. Copyright © 2018 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  5. Important issues in the justification of a control treatment in paediatric drug trials.

    PubMed

    Kelly, Lauren E; Davies, Elin Haf; Saint-Raymond, Agnes; Tomasi, Paolo; Offringa, Martin

    2016-10-01

    The value of comparative effectiveness trials in informing clinical and policy decisions depends heavily on the choice of control arm (comparator). Our objective is to identify challenges in comparator reasoning and to determine justification criteria for selecting a control arm in paediatric clinical trials. A literature search was completed to identify existing sources of guidance on comparator selection. Subsequently, we reviewed a randomly selected sample of comparators selected for paediatric investigation plans (PIPs) adopted by the Paediatric Committee of the European Medicines Agency in 2013. We gathered descriptive information and evaluated their review process to identify challenges and compromises between regulators and sponsors with regard to the selection of the comparator. A tool to help investigators justify the selection of active controls and placebo arms was developed using the existing literature and empirical data. Justifying comparator selection was a challenge in 28% of PIPs. The following challenging paediatric issues in the decision-making process were identified: use of off-label medications as comparators, ethical and safe use of placebo, duration of placebo use, an undefined optimal dosing strategy, lack of age-appropriate safety and efficacy data, and drug dosing not supported by extrapolation of safety/efficacy evidence from other populations. In order to generate trials that will inform clinical decision-making and support marketing authorisations, researchers must systemically and transparently justify their selection of the comparator arm for their study. This report highlights key areas for justification in the choice of comparator in paediatric clinical trials. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  6. 48 CFR 873.104 - Competition requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... be approved if determined legally to be associated with affiliated institutions), or from blood banks, organ banks, or research centers, the resource may be acquired on a sole source basis. (38 U.S.C. 8153...

  7. 13 CFR 126.600 - What are HUBZone contracts?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... qualified HUBZone SBC through any of the following procurement methods: (a) Sole source awards to qualified...) Awards to qualified HUBZone SBCs through full and open competition after a price evaluation preference in...

  8. 46 CFR 112.35-7 - Activating means.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-7 Activating means. The activating...

  9. 46 CFR 112.35-7 - Activating means.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-7 Activating means. The activating...

  10. Emerging contaminants at a closed and an operating landfill in Oklahoma

    USGS Publications Warehouse

    Andrews, William J.; Masoner, Jason R.; Cozzarelli, Isabelle M.

    2012-01-01

    Landfills are the final depositories for a wide range of solid waste from both residential and commercial sources, and therefore have the potential to produce leachate containing many organic compounds found in consumer products such as pharmaceuticals, plasticizers, disinfectants, cleaning agents, fire retardants, flavorings, and preservatives, known as emerging contaminants (ECs). Landfill leachate was sampled from landfill cells of three different age ranges from two landfills in Central Oklahoma. Samples were collected from an old cell containing solid waste greater than 25 years old, an intermediate age cell with solid waste between 16 and 3 years old, and operating cell with solid waste less than 5 years old to investigate the chemical variability and persistence of selected ECs in landfill leachate of differing age sources. Twenty-eight of 69 analyzed ECs were detected in one or more samples from the three leachate sources. Detected ECs ranged in concentration from 0.11 to 114 μg/L and included 4 fecal and plant sterols, 13 household\\industrial, 7 hydrocarbon, and 4 pesticide compounds. Four ECs were solely detected in the oldest leachate sample, two ECs were solely detected in the intermediate leachate sample, and no ECs were solely detected in the youngest leachate sample. Eleven ECs were commonly detected in all three leachate samples and are an indication of the contents of solid waste deposited over several decades and the relative resistance of some ECs to natural attenuation processes in and near landfills.

  11. Stable isotopes in juvenile marine fishes and their invertebrate prey from the Thames Estuary, UK, and adjacent coastal regions

    NASA Astrophysics Data System (ADS)

    Leakey, Chris D. B.; Attrill, Martin J.; Jennings, Simon; Fitzsimons, Mark F.

    2008-04-01

    Estuaries are regarded as valuable nursery habitats for many commercially important marine fishes, potentially providing a thermal resource, refuge from predators and a source of abundant prey. Stable isotope analysis may be used to assess relative resource use from isotopically distinct sources. This study comprised two major components: (1) development of a spatial map and discriminant function model of stable isotope variation in selected invertebrate groups inhabiting the Thames Estuary and adjacent coastal regions; and (2) analysis of stable isotope signatures of juvenile bass ( Dicentrarchus labrax), sole ( Solea solea) and whiting ( Merlangius merlangus) for assessment of resource use and feeding strategies. The data were also used to consider anthropogenic enrichment of the estuary and potential energetic benefits of feeding in estuarine nursery habitat. Analysis of carbon (δ 13C), nitrogen (δ 15N) and sulphur (δ 34S) isotope data identified significant differences in the 'baseline' isotopic signatures between estuarine and coastal invertebrates, and discriminant function analysis allowed samples to be re-classified to estuarine and coastal regions with 98.8% accuracy. Using invertebrate signatures as source indicators, stable isotope data classified juvenile fishes to the region in which they fed. Feeding signals appear to reflect physiological (freshwater tolerance) and functional (mobility) differences between species. Juvenile sole were found to exist as two isotopically-discrete sub-populations, with no evidence of mixing between the two. An apparent energetic benefit of estuarine feeding was only found for sole.

  12. Isolation and characterization of heterotrophic bacteria able to grow aerobically with quaternary ammonium alcohols as sole source of carbon and nitrogen.

    PubMed

    Kaech, Andres; Vallotton, Nathalie; Egli, Thomas

    2005-04-01

    The quaternary ammonium alcohols (QAAs) 2,3-dihydroxypropyl-trimethyl-ammonium (TM), dimethyl-diethanol-ammonium (DM) and methyl-triethanol-ammonium (MM) are hydrolysis products of their parent esterquat surfactants, which are widely used as softeners in fabric care. We isolated several bacteria growing with QAAs as the sole source of carbon and nitrogen. The strains were compared with a previously isolated TM-degrading bacterium, which was identified as a representative of the species Pseudomonas putida (Syst. Appl. Microbiol. 24 (2001) 252). Two bacteria were isolated with DM, referred to as strains DM 1 and DM 2, respectively. Based on 16S-rDNA analysis, they provided 97% (DM 1) and 98% (DM 2) identities to the closest related strain Zoogloea ramigera Itzigsohn 1868AL. Both strains were long, slim, motile rods but only DM 1 showed the floc forming activity, which is typical for representatives of the genus Zoogloea. Using MM we isolated a Gram-negative, non-motile rod referred to as strain MM 1. The 16S-rDNA sequence of the isolated bacterium revealed 94% identities (best match) to Rhodobacter sphaeroides only. The strains MM 1 and DM 1 exclusively grew with the QAA which was used for their isolation. DM 2 was also utilizing TM as sole source of carbon and nitrogen. However, all of the isolated bacteria were growing with the natural and structurally related compound choline.

  13. Anaerobic oxidation of 2-chloroethanol under denitrifying conditions by Pseudomonas stutzeri strain JJ.

    PubMed

    Dijk, J A; Stams, A J M; Schraa, G; Ballerstedt, H; de Bont, J A M; Gerritse, J

    2003-11-01

    A bacterium that uses 2-chloroethanol as sole energy and carbon source coupled to denitrification was isolated from 1,2-dichloroethane-contaminated soil. Its 16 S rDNA sequence showed 98% similarity with the type strain of Pseudomonas stutzeri (DSM 5190) and the isolate was tentatively identified as Pseudomonas stutzeri strain JJ. Strain JJ oxidized 2-chloroethanol completely to CO(2) with NO(3)(- )or O(2) as electron acceptor, with a preference for O(2) if supplied in combination. Optimum growth on 2-chloroethanol with nitrate occurred at 30 degrees C with a mu(max) of 0.14 h(-1) and a yield of 4.4 g protein per mol 2-chloroethanol metabolized. Under aerobic conditions, the mu(max) was 0.31 h(-1). NO(2)(-) also served as electron acceptor, but reduction of Fe(OH)(3), MnO(2), SO(4)(2-), fumarate or ClO(3)(-) was not observed. Another chlorinated compound used as sole energy and carbon source under aerobic and denitrifying conditions was chloroacetate. Various different bacterial strains, including some closely related Pseudomonas stutzeri strains, were tested for their ability to grow on 2-chloroethanol as sole energy and carbon source under aerobic and denitrifying conditions, respectively. Only three strains, Pseudomonas stutzeri strain LMD 76.42, Pseudomonas putida US2 and Xanthobacter autotrophicus GJ10, grew aerobically on 2-chloroethanol. This is the first report of oxidation of 2-chloroethanol under denitrifying conditions by a pure bacterial culture.

  14. Scale-up of an alkaline protease from Bacillus pumilus MTCC 7514 utilizing fish meal as a sole source of nutrients.

    PubMed

    Gupta, Rishikesh Kumar; Prasad, Dinesh; Sathesh, Jaykumar; Naidu, Ramachandra Boopathy; Kamini, Numbi Ramudu; Palanivel, Saravanan; Gowthaman, Marichetti Kuppuswami

    2012-09-01

    Fish meal grades SL1 and SL2 from Sardine (Sardinella longiceps) and NJ from Pink Perch (Nemipterus japonicas) were evaluated as a sole source of carbon and nitrogen in the medium for alkaline protease production by Bacillus pumilus MTCC 7514. The analysis of the fish meal suggests that the carbon and nitrogen contents in fish meal are sufficient to justify its choice as replacement for other nutrients. Protease production increased significantly (4,914 U/ml) in medium containing only fish meal, compared with the basal medium (2,646 U/ml). However, the elimination of inorganic salts from media reduced the protease productivity. In addition, all the three grades of fish meal yielded almost the same amounts of protease when employed as the sole source of carbon and nitrogen. Nevertheless, the best results were observed in fish meal SL1 medium. Furthermore, protease production was enhanced to 6,966 U/ml and 7,047 U/ml on scaling up from flask (4,914 U/ml) to 3.7 and 20 L fermenters, respectively, using fish meal (10 g/l). Similarly, the corresponding improvement in productivities over flask (102.38 U/ml/h) was 193.5 and 195.75 U/ml/h in 3.7 and 20 L fermenters, respectively. The crude protease was found to have dehairing ability in leather processing, which is bound to have great environmental benefits.

  15. 75 FR 34096 - Application(s) for Duty-Free Entry of Scientific Instruments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... dynamin, using negative stain nad cryo-electron microscopy methods. Justification for Duty-Free Entry..., using negative stain nad cryo-electron microscopy methods. Justification for Duty-Free Entry: There are...

  16. Men's response to their wives' participation in microfinance: perpetration and justification of intimate partner violence in Bangladesh.

    PubMed

    Murshid, N S

    2016-12-01

    The present study adds to extant literature on the association between microfinance participation and intimate partner violence (IPV) by assessing a national sample of men married to microfinance participants. The key objective was to assess whether there was a positive association between wives' microfinance participation and men's perpetration and justification of IPV in urban areas of Bangladesh. This study is based on a population-based secondary data analysis. In this cross-sectional study, data from a national sample of men from the 2007 Bangladesh Demographic and Health Survey were analysed using logistic regression analyses. IPV perpetration was measured using a modified Conflict Tactics Scale and justification of IPV was measured based on 'justification of wife beating' statements with which men agreed or disagreed. Men married to microfinance participants were not significantly different from men married to non-participants of microfinance in terms of IPV perpetration in both urban and rural areas. However, the interaction effect of wives' microfinance participation and urban living on men's justification of IPV revealed a significant and positive beta coefficient. Specifically, wives' participation in microfinance was positively associated with men's justification of IPV in urban areas (β = 0.51, P < 0.05). Microfinance organizations in urban areas should bundle microfinancial services with IPV screening and intervention geared toward men and women. Copyright © 2016 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  17. Enhanced biological phosphorus removal in a sequencing batch reactor using propionate as the sole carbon source.

    PubMed

    Pijuan, M; Saunders, A M; Guisasola, A; Baeza, J A; Casas, C; Blackall, L L

    2004-01-05

    An enhanced biological phosphorus removal (EBPR) system was developed in a sequencing batch reactor (SBR) using propionate as the sole carbon source. The microbial community was followed using fluorescence in situ hybridization (FISH) techniques and Candidatus 'Accumulibacter phosphatis' were quantified from the start up of the reactor until steady state. A series of SBR cycle studies was performed when 55% of the SBR biomass was Accumulibacter, a confirmed polyphosphate accumulating organism (PAO) and when Candidatus 'Competibacter phosphatis', a confirmed glycogen-accumulating organism (GAO), was essentially undetectable. These experiments evaluated two different carbon sources (propionate and acetate), and in every case, two different P-release rates were detected. The highest rate took place while there was volatile fatty acid (VFA) in the mixed liquor, and after the VFA was depleted a second P-release rate was observed. This second rate was very similar to the one detected in experiments performed without added VFA.A kinetic and stoichiometric model developed as a modification of Activated Sludge Model 2 (ASM2) including glycogen economy, was fitted to the experimental profiles. The validation and calibration of this model was carried out with the cycle study experiments performed using both VFAs. The effect of pH from 6.5 to 8.0 on anaerobic P-release and VFA-uptake and aerobic P-uptake was also studied using propionate. The optimal overall working pH was around 7.5. This is the first study of the microbial community involved in EBPR developed with propionate as a sole carbon source along with detailed process performance investigations of the propionate-utilizing PAOs. Copyright 2003 Wiley Periodicals, Inc.

  18. Addendum to the Final Audit Report on Procurement of Spare Parts and Supplies

    DTIC Science & Technology

    1993-06-04

    Contraves USA, Simulation and Systems Integration, Tampa, FL Contract No.: N00104-89-G-A050-4009 Awarded: April 20, 1990 Procurement Method...awarded sole source to Contraves . The amplifier is a source-controlled item, and Contraves is the only approved source. There are no commercial...The total contract value was $69,552. Contraves assembled and tested the amplifiers. For the subject procurement, Contraves paid $* per unit for the

  19. Nuclear Criticality Safety Data Book

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hollenbach, D. F.

    The objective of this document is to support the revision of criticality safety process studies (CSPSs) for the Uranium Processing Facility (UPF) at the Y-12 National Security Complex (Y-12). This design analysis and calculation (DAC) document contains development and justification for generic inputs typically used in Nuclear Criticality Safety (NCS) DACs to model both normal and abnormal conditions of processes at UPF to support CSPSs. This will provide consistency between NCS DACs and efficiency in preparation and review of DACs, as frequently used data are provided in one reference source.

  20. The implementation, interpretation, and justification of likelihoods in cosmology

    NASA Astrophysics Data System (ADS)

    McCoy, C. D.

    2018-05-01

    I discuss the formal implementation, interpretation, and justification of likelihood attributions in cosmology. I show that likelihood arguments in cosmology suffer from significant conceptual and formal problems that undermine their applicability in this context.

  1. Quality indicators for acute myocardial infarction: A position paper of the Acute Cardiovascular Care Association.

    PubMed

    Schiele, Francois; Gale, Chris P; Bonnefoy, Eric; Capuano, Frederic; Claeys, Marc J; Danchin, Nicolas; Fox, Keith Aa; Huber, Kurt; Iakobishvili, Zaza; Lettino, Maddalena; Quinn, Tom; Rubini Gimenez, Maria; Bøtker, Hans E; Swahn, Eva; Timmis, Adam; Tubaro, Marco; Vrints, Christiaan; Walker, David; Zahger, Doron; Zeymer, Uwe; Bueno, Hector

    2017-02-01

    Evaluation of quality of care is an integral part of modern healthcare, and has become an indispensable tool for health authorities, the public, the press and patients. However, measuring quality of care is difficult, because it is a multifactorial and multidimensional concept that cannot be estimated solely on the basis of patients' clinical outcomes. Thus, measuring the process of care through quality indicators (QIs) has become a widely used practice in this context. Other professional societies have published QIs for the evaluation of quality of care in the context of acute myocardial infarction (AMI), but no such indicators exist in Europe. In this context, the European Society of Cardiology (ESC) Acute Cardiovascular Care Association (ACCA) has reflected on the measurement of quality of care in the context of AMI (ST segment elevation myocardial infarction (STEMI) and non-ST segment elevation myocardial infarction (NSTEMI)) and created a set of QIs, with a view to developing programmes to improve quality of care for the management of AMI across Europe. We present here the list of QIs defined by the ACCA, with explanations of the methodology used, scientific justification and reasons for the choice for each measure.

  2. Fiscal Year (FY) 2001 Budget Estimates. Army National Guard. Military Construction Program FY 2001. Justification Data Submission to Congress. Department of the Army.

    DTIC Science & Technology

    2000-02-01

    CONSIDERATIONS ix-xx FUTURE YEARS DEFENSE PLAN AUDIT TRAIL xxi-xxiii PROJECT JUSTIFICATION DOCUMENTS 1-149 PLANNING & DESIGN JUSTIFICATION DOCUMENT 15 0...OUTSTANDING POLUTION AND SAFETY DEFICIENCIES: DDl°™1390s2 MAY 78 1. COMPONENT FY 2001 GUARD AND RESERVE 2. DATE ARNG MILITARY CONSTRUCTION FEB00 3...TOTAL 36 286 13 MAJOR EQUIPMENT AND AIRCRAFT TYPE AUTHORIZED ASSIGNED 14. OUTSTANDING POLUTION AND SAFETY DEFICIENCIES: DD:A O™1390S2 1

  3. Design and Implementation of a Prototype Microcomputer Database Management System for the Standardization of Data Elements for the Department of Defense

    DTIC Science & Technology

    1990-09-01

    Justification Cat: Left Timeliness Identifier: Qwe (FI] Domain I Def Text: -Press [F3 to nove in/out of the fields below. Use ARROW keys to scroll- Rec: Host...Delete a record Elemont Creator ID: Justification Cat: Left Timeliness Identifier: Qwe [FI) Domain Def Text: - Press (F3) to move in/out of the...Number: 1 Alias Name: Accounting Code Data Value Type ID: QL Max Length Characters: 34 Timeliness ID: Qwe Justification Category: Left Creator ID: Domain

  4. 76 FR 35842 - Endangered and Threatened Species; Take of Anadromous Fish

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... populations. These recommendations are not formal ESA standards nor will they constitute the sole source of.... However, debating the relative magnitude of improvements in productivity that might occur from a given set...

  5. 40 CFR 149.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of the Safe Drinking Water Act (SDWA). ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Purpose. 149.1 Section 149.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) SOLE SOURCE...

  6. 40 CFR 149.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of the Safe Drinking Water Act (SDWA). ... 40 Protection of Environment 23 2011-07-01 2011-07-01 false Purpose. 149.1 Section 149.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) SOLE SOURCE...

  7. 13 CFR 124.403 - How is a business plan updated and modified?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... aggregate dollar value of 8(a) contracts to be sought, broken down by sole source and competitive... primary industry classification falls within that Major Group. Any adjustment will take into account...

  8. 21 CFR 558.369 - Nitarsone.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... edible tissues. The drug is dangerous for ducks, geese, and dogs. Overdosage or lack of water may result... dangerous for ducks, geese, and dogs. Use as sole source of arsenic. [46 FR 47535, Sept. 29, 1981, as...

  9. 21 CFR 558.369 - Nitarsone.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... edible tissues. The drug is dangerous for ducks, geese, and dogs. Overdosage or lack of water may result... dangerous for ducks, geese, and dogs. Use as sole source of arsenic. [46 FR 47535, Sept. 29, 1981, as...

  10. 21 CFR 558.369 - Nitarsone.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... edible tissues. The drug is dangerous for ducks, geese, and dogs. Overdosage or lack of water may result... dangerous for ducks, geese, and dogs. Use as sole source of arsenic. [46 FR 47535, Sept. 29, 1981, as...

  11. 21 CFR 558.369 - Nitarsone.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... edible tissues. The drug is dangerous for ducks, geese, and dogs. Overdosage or lack of water may result... dangerous for ducks, geese, and dogs. Use as sole source of arsenic. [46 FR 47535, Sept. 29, 1981, as...

  12. 21 CFR 558.369 - Nitarsone.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... edible tissues. The drug is dangerous for ducks, geese, and dogs. Overdosage or lack of water may result... dangerous for ducks, geese, and dogs. Use as sole source of arsenic. [46 FR 47535, Sept. 29, 1981, as...

  13. Appealing to the crowd: ethical justifications in Canadian medical crowdfunding campaigns

    PubMed Central

    Snyder, Jeremy; Crooks, Valorie A; Mathers, Annalise; Chow-White, Peter

    2017-01-01

    Medical crowdfunding is growing in terms of the number of active campaigns, amount of funding raised and public visibility. Little is known about how campaigners appeal to potential donors outside of anecdotal evidence collected in news reports on specific medical crowdfunding campaigns. This paper offers a first step towards addressing this knowledge gap by examining medical crowdfunding campaigns for Canadian recipients. Using 80 medical crowdfunding campaigns for Canadian recipients, we analyse how Canadians justify to others that they ought to contribute to funding their health needs. We find the justifications campaigners tend to fall into three themes: personal connections, depth of need and giving back. We further discuss how these appeals can understood in terms of ethical justifications for giving and how these justifications should be assessed in light of the academic literature on ethical concerns raised by medical crowdfunding. PMID:28137998

  14. System justification, the denial of global warming, and the possibility of "system-sanctioned change".

    PubMed

    Feygina, Irina; Jost, John T; Goldsmith, Rachel E

    2010-03-01

    Despite extensive evidence of climate change and environmental destruction, polls continue to reveal widespread denial and resistance to helping the environment. It is posited here that these responses are linked to the motivational tendency to defend and justify the societal status quo in the face of the threat posed by environmental problems. The present research finds that system justification tendencies are associated with greater denial of environmental realities and less commitment to pro-environmental action. Moreover, the effects of political conservatism, national identification, and gender on denial of environmental problems are explained by variability in system justification tendencies. However, this research finds that it is possible to eliminate the negative effect of system justification on environmentalism by encouraging people to regard pro-environmental change as patriotic and consistent with protecting the status quo (i.e., as a case of "system-sanctioned change"). Theoretical and practical implications of these findings are discussed.

  15. Justification bias in self-reported disability: New evidence from panel data.

    PubMed

    Black, Nicole; Johnston, David W; Suziedelyte, Agne

    2017-07-01

    The relationship between health and work is frequently investigated using self-assessments of disability from social surveys. The complication is that respondents may overstate their level of disability to justify non-employment and welfare receipt. This study provides new evidence on the existence and magnitude of justification bias by exploiting a novel feature of a large longitudinal survey: each wave respondents are asked identical disability questions twice; near the beginning and end of the face-to-face interview. Prior to answering the second disability question, respondents are asked a series of questions that increase the salience of their employment and welfare circumstances. Justification bias is identified by comparing the variation between the two measures within-individuals over time, with the variation in employment status over time. Results indicate substantial and statistically significant justification bias; especially for men and women who receive disability pensions. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Only lasers can be used for low level laser therapy

    PubMed Central

    Moskvin, Sergey Vladimirovich

    2017-01-01

    The question of lasers' exclusivity, as well as the degree of influence of special properties of low-intensity laser illumination (LILI), such as coherence, polarity and monochromaticity, on the effectiveness of low level laser therapy (LLLT) continues to cause arguments. The study analyzes publications from 1973 to 2016, in which laser and conventional light sources are compared, and the following conclusions are drawn. First, there are a lot of publications with incorrect comparison or unfounded statements. Secondly, other sources of light are often meant by LILI without any justification. Thirdly, all studies, in which the comparison is carried out correctly and close parameters of the impact and the model are used, have a firm conclusion that laser light is much more effective. Fourthly, it is uniquely identified that the most important parameter that determines the efficiency of lasers is monochromaticity, i.e., a much narrower spectral width than for all other light sources. Only laser light sources can be used for LLLT! PMID:29130447

  17. Open-Source web-based geographical information system for health exposure assessment

    PubMed Central

    2012-01-01

    This paper presents the design and development of an open source web-based Geographical Information System allowing users to visualise, customise and interact with spatial data within their web browser. The developed application shows that by using solely Open Source software it was possible to develop a customisable web based GIS application that provides functions necessary to convey health and environmental data to experts and non-experts alike without the requirement of proprietary software. PMID:22233606

  18. A method for separation of heavy metal sources in urban groundwater using multiple lines of evidence.

    PubMed

    Hepburn, Emily; Northway, Anne; Bekele, Dawit; Liu, Gang-Jun; Currell, Matthew

    2018-06-11

    Determining sources of heavy metals in soils, sediments and groundwater is important for understanding their fate and transport and mitigating human and environmental exposures. Artificially imported fill, natural sediments and groundwater from 240 ha of reclaimed land at Fishermans Bend in Australia, were analysed for heavy metals and other parameters to determine the relative contributions from different possible sources. Fishermans Bend is Australia's largest urban re-development project, however, complicated land-use history, geology, and multiple contamination sources pose challenges to successful re-development. We developed a method for heavy metal source separation in groundwater using statistical categorisation of the data, analysis of soil leaching values and fill/sediment XRF profiling. The method identified two major sources of heavy metals in groundwater: 1. Point sources from local or up-gradient groundwater contaminated by industrial activities and/or legacy landfills; and 2. contaminated fill, where leaching of Cu, Mn, Pb and Zn was observed. Across the precinct, metals were most commonly sourced from a combination of these sources; however, eight locations indicated at least one metal sourced solely from fill leaching, and 23 locations indicated at least one metal sourced solely from impacted groundwater. Concentrations of heavy metals in groundwater ranged from 0.0001 to 0.003 mg/L (Cd), 0.001-0.1 mg/L (Cr), 0.001-0.2 mg/L (Cu), 0.001-0.5 mg/L (Ni), 0.001-0.01 mg/L (Pb), and 0.005-1.2 mg/L (Zn). Our method can determine the likely contribution of different metal sources to groundwater, helping inform more detailed contamination assessments and precinct-wide management and remediation strategies. Copyright © 2018 Elsevier Ltd. All rights reserved.

  19. 49 CFR 611.9 - Project justification criteria for grants and loans for fixed guideway systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... evaluations and assign ratings for project justification, FTA will evaluate information developed locally... of the criteria will be expressed in terms of descriptive indicators, as follows: “high,” “medium...

  20. 49 CFR 611.9 - Project justification criteria for grants and loans for fixed guideway systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... evaluations and assign ratings for project justification, FTA will evaluate information developed locally... of the criteria will be expressed in terms of descriptive indicators, as follows: “high,” “medium...

  1. 49 CFR 611.9 - Project justification criteria for grants and loans for fixed guideway systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... evaluations and assign ratings for project justification, FTA will evaluate information developed locally... of the criteria will be expressed in terms of descriptive indicators, as follows: “high,” “medium...

  2. Role of Reduced Exogenous Organic Compounds in the Physiology of the Blue-Green Bacteria (Algae): Photoheterotrophic Growth of a “Heterotrophic” Blue-Green Bacterium

    PubMed Central

    Ingram, L. O.; Calder, J. A.; Van Baalen, C.; Plucker, F. E.; Parker, P. L.

    1973-01-01

    Nostoc sp. (strain Mac) was shown to be capable of using glucose, fructose, or sucrose as a sole source of carbon and energy in the dark. In the light in the absence of exogenously supplied CO2, this strain exhibited a more versatile metabolism. In addition to the three sugars above, glycerol and acetate served as sole sources of carbon. This photoheterotrophic growth in the absence of exogenously supplied CO2 appears to involve O2-evolving photosynthesis. The action spectrum for photoheterotrophic growth on acetate closely resembles the action spectrum for photosynthesis. The physiology of photoheterotrophic growth was further investigated through determinations of stable carbon isotope ratios and measurements of gas exchanges. These investigations suggest that respired CO2 from substrate oxidation is assimilated by the photosynthetic machinery. PMID:4196252

  3. Microbial Degradation of Isopropyl-N-3-Chlorophenylcarbamate and 2-Chloroethyl-N-3-Chlorophenylcarbamate

    PubMed Central

    Kaufman, D. D.; Kearney, P. C.

    1965-01-01

    Microbial degradation of isopropyl-N-3-chlorophenylcarbamate (CIPC) and 2-chloroethyl-N-3-chlorophenylcarbamate (CEPC) was observed in a soil perfusion system. Degradation in perfused soils, and by pure cultures of effective bacterial isolates, was demonstrated by the production of 3-chloroaniline and the subsequent liberation of free chloride ion. Identified isolates effective in degrading and utilizing CIPC as a sole source of carbon included Pseudomonas striata Chester, a Flavobacterium sp., an Agrobacterium sp., and an Achromobacter sp. Identified isolates, effective in degrading and utilizing CEPC as a sole source of carbon, included an Achromobacter sp. and an Arthrobacter sp. CIPC-effective isolates degraded CEPC more slowly than CIPC, whereas CEPC-effective isolates degraded CIPC more rapidly than CEPC. Both CIPC- and CEPC-effective isolates degraded isopropyl N-phenylcarbamate (IPC) more rapidly than either CIPC or CEPC. Images Fig. 3 PMID:14325285

  4. Biodegradation of chlorpyrifos by lactic acid bacteria during kimchi fermentation.

    PubMed

    Cho, Kye Man; Math, Reukaradhya K; Islam, Shah Md Asraful; Lim, Woo Jin; Hong, Su Young; Kim, Jong Min; Yun, Myoung Geun; Cho, Ji Joong; Yun, Han Dae

    2009-03-11

    We examined the role of microorganisms in the degradation of the organophosphorus (OP) insecticide chlorpyrifos (CP) during kimchi fermentation. During the fermentation of kimchi, 30 mg L(-1) of CP was added and its stability assayed during fermentation. CP was degraded rapidly until day 3 (83.3%) and degraded completely by day 9. Four CP-degrading lactic acid bacteria (LAB) were isolated from kimchi fermentation in the presence of 200 mg L(-1) CP and were identified as Leuconostoc mesenteroides WCP907, Lactobacillus brevis WCP902, Lactobacillus plantarum WCP931, and Lactobacillus sakei WCP904. CP could be utilized by these four strains as the sole source of carbon and phosphorus. Coumaphos (CM), diazinon (DZ), parathion (PT), and methylparathion (MPT) were also degraded by WCP907, WCP902, WCP931, and WCP904 when provided as sole sources of carbon and phosphorus.

  5. Initial proteome analysis of caffeine-induced proteins in Aspergillus tamarii using two-dimensional fluorescence difference gel electrophoresis.

    PubMed

    Gutiérrez-Sánchez, Gerardo; Atwood, James; Kolli, V S Kumar; Roussos, Sévastianos; Augur, Christopher

    2012-04-01

    Caffeine is toxic to most microorganisms. However, some filamentous fungi, such as Aspergillus tamarii, are able to metabolize this alkaloid when fed caffeine as the sole nitrogen source. The aim of the present work was to identify intracellular A. tamarii proteins, regulated by caffeine, using fluorescence difference two-dimensional gel electrophoresis. Specific proteins from two culture media of A. tamarii grown either on ammonium sulfate or caffeine as the sole nitrogen source were analysed by mass spectrometry. Thirteen out of a total of 85 differentially expressed spots were identified after database search. Identified up-regulated proteins include phosphoglycerate kinase, malate dehydrogenase, dyp-type peroxidase family protein, heat shock protein, Cu, Zn superoxidase dismutase and xanthine dehydrogenase. Some of the proteins identified in this study are involved in the caffeine degradation pathway as well as in stress response, suggesting that stress proteins could be involved in caffeine metabolism in filamentous fungi.

  6. Essays on Environmental Economics and Policy

    NASA Astrophysics Data System (ADS)

    Walker, W. Reed

    A central feature of modern government is its role in designing welfare improving policies to address and correct market failures stemming from externalities and public goods. The rationale for most modern environmental regulations stems from the failure of markets to efficiently allocate goods and services. Yet, as with any policy, distributional effects are important there exist clear winners and losers. Despite the clear theoretical justification for environmental and energy policy, empirical work credibly identifying both the source and consequences of these externalities as well as the distributional effects of existing policies remains in its infancy. My dissertation focuses on the development of empirical methods to investigate the role of environmental and energy policy in addressing market failures as well as exploring the distributional implications of these policies. These questions are important not only as a justification for government intervention into markets but also for understanding how distributional consequences may shape the design and implementation of these policies. My dissertation investigates these questions in the context of programs and policies that are important in their own right. Chapters 1 and 2 of my dissertation explore the economic costs and distributional implications associated with the largest environmental regulatory program in the United States, the Clean Air Act. Chapters 3 and 4 examine the social costs of air pollution in the context of transportation externalities, showing how effective transportation policy has additional co-benefits in the form of environmental policy. My dissertation remains unified in both its subject matter and methodological approach -- using unique sources of data and sound research designs to understand important issues in environmental policy.

  7. Growth of Prototheca isolates on n-hexadecane and mixed-hydrocarbon substrate.

    PubMed Central

    Walker, J D; Pore, R S

    1978-01-01

    Prototheca zopfii, an achlorphyllous alga, was capable of using hydrocarbons as sole carbon and energy source. The ability of P. zopfii to use hydrocarbons did not correlate with source of isolation. Seventy-five percent of the P. zopfii cultures recovered from sewage, plants, or animals utilized hydrocarbons. Other Prototheca species and P. zopfii that did not utilize hydrocarbons were isolated simultaneously from several sources with isolates that did use hydrocarbons. Species type rather than source of isolation was the predominant factor that determined hydrocarbon utilization. PMID:565616

  8. Key Enzymes Enabling the Growth of Arthrobacter sp. Strain JBH1 with Nitroglycerin as the Sole Source of Carbon and Nitrogen

    PubMed Central

    Husserl, Johana; Hughes, Joseph B.

    2012-01-01

    Flavoprotein reductases that catalyze the transformation of nitroglycerin (NG) to dinitro- or mononitroglycerols enable bacteria containing such enzymes to use NG as the nitrogen source. The inability to use the resulting mononitroglycerols limits most strains to incomplete denitration of NG. Recently, Arthrobacter strain JBH1 was isolated for the ability to grow on NG as the sole source of carbon and nitrogen, but the enzymes and mechanisms involved were not established. Here, the enzymes that enable the Arthrobacter strain to incorporate NG into a productive pathway were identified. Enzyme assays indicated that the transformation of nitroglycerin to mononitroglycerol is NADPH dependent and that the subsequent transformation of mononitroglycerol is ATP dependent. Cloning and heterologous expression revealed that a flavoprotein catalyzes selective denitration of NG to 1-mononitroglycerol (1-MNG) and that 1-MNG is transformed to 1-nitro-3-phosphoglycerol by a glycerol kinase homolog. Phosphorylation of the nitroester intermediate enables the subsequent denitration of 1-MNG in a productive pathway that supports the growth of the isolate and mineralization of NG. PMID:22427495

  9. Key enzymes enabling the growth of Arthrobacter sp. strain JBH1 with nitroglycerin as the sole source of carbon and nitrogen.

    PubMed

    Husserl, Johana; Hughes, Joseph B; Spain, Jim C

    2012-05-01

    Flavoprotein reductases that catalyze the transformation of nitroglycerin (NG) to dinitro- or mononitroglycerols enable bacteria containing such enzymes to use NG as the nitrogen source. The inability to use the resulting mononitroglycerols limits most strains to incomplete denitration of NG. Recently, Arthrobacter strain JBH1 was isolated for the ability to grow on NG as the sole source of carbon and nitrogen, but the enzymes and mechanisms involved were not established. Here, the enzymes that enable the Arthrobacter strain to incorporate NG into a productive pathway were identified. Enzyme assays indicated that the transformation of nitroglycerin to mononitroglycerol is NADPH dependent and that the subsequent transformation of mononitroglycerol is ATP dependent. Cloning and heterologous expression revealed that a flavoprotein catalyzes selective denitration of NG to 1-mononitroglycerol (1-MNG) and that 1-MNG is transformed to 1-nitro-3-phosphoglycerol by a glycerol kinase homolog. Phosphorylation of the nitroester intermediate enables the subsequent denitration of 1-MNG in a productive pathway that supports the growth of the isolate and mineralization of NG.

  10. Heterotrophic cultivation of Chlorella pyrenoidosa using sucrose as the sole carbon source by co-culture with Rhodotorula glutinis.

    PubMed

    Wang, Shikai; Wu, Yong; Wang, Xu

    2016-11-01

    Heterotrophic cultivation of microalgae is a feasible alternative strategy to avoid the light limitation of photoautotrophic culture, but the heterotrophic utilization of disaccharides is difficult for microalgae. Aimed at this problem, a co-culture system was developed by mix culture of C. pyrenoidosa and R. glutinis using sucrose as the sole carbon source. In this system, C. pyrenoidosa could utilize glucose and fructose which were hydrolyzed from sucrose by R. glutinis. The highest specific growth rate and final cell number proportion of algae was 1.02day(-1) and 45%, respectively, when cultured at the initial algal cell number proportion of 95.24% and the final algal cell density was 111.48×10(6)cells/mL. In addition, the lipid content was also promoted due to the synergistic effects in mix culture. This study provides a novel approach using sucrose-riched wastes for the heterotrophic culture of microalgae and may effectively decrease the cost of carbon source. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Justification of diagnostic medical exposures: some practical issues. Report of an International Atomic Energy Agency Consultation.

    PubMed

    Malone, J; Guleria, R; Craven, C; Horton, P; Järvinen, H; Mayo, J; O'reilly, G; Picano, E; Remedios, D; Le Heron, J; Rehani, M; Holmberg, O; Czarwinski, R

    2012-05-01

    The Radiation Protection of Patients Unit of the International Atomic Energy Agency (IAEA) is concerned about the effectiveness of justification of diagnostic medical exposures. Recent published work and the report of an initial IAEA consultation in the area gave grounds for such concerns. There is a significant level of inappropriate usage, and, in some cases, a poor level of awareness of dose and risk among some key groups involved. This article aims to address this. The IAEA convened a second group of experts in November 2008 to review practical and achievable actions that might lead to more effective justification. This report summarises the matters that this group considered and the outcome of their deliberations. There is a need for improved communication, both within professions and between professionals on one hand, and between professionals and the patients/public on the other. Coupled with this, the issue of consent to imaging procedures was revisited. The need for good evidence-based referral guidelines or criteria of acceptability was emphasised, as was the need for their global adaptation and dissemination. Clinical audit was regarded as a key tool in ensuring that justification becomes an effective, transparent and accountable part of normal radiological practice. In summary, justification would be facilitated by the "3 As": awareness, appropriateness and audit.

  12. Nitrogen transformation under different dissolved oxygen levels by the anoxygenic phototrophic bacterium Marichromatium gracile.

    PubMed

    Hong, Xuan; Chen, Zhongwei; Zhao, Chungui; Yang, Suping

    2017-06-01

    Marichromatium gracile: YL28 (M. gracile YL28) is an anoxygenic phototrophic bacterial strain that utilizes ammonia, nitrate, or nitrite as its sole nitrogen source during growth. In this study, we investigated the removal and transformation of ammonium, nitrate, and nitrite by M. gracile YL28 grown in a combinatorial culture system of sodium acetate-ammonium, sodium acetate-nitrate and sodium acetate-nitrite in response to different initial dissolved oxygen (DO) levels. In the sodium acetate-ammonium system under aerobic conditions (initial DO = 7.20-7.25 mg/L), we detected a continuous accumulation of nitrate and nitrite. However, under semi-anaerobic conditions (initial DO = 4.08-4.26 mg/L), we observed a temporary accumulation of nitrate and nitrite. Interestingly, under anaerobic conditions (initial DO = 0.36-0.67 mg/L), there was little accumulation of nitrate and nitrite, but an increase in nitrous oxide production. In the sodium acetate-nitrite system, nitrite levels declined slightly under aerobic conditions, and nitrite was completely removed under semi-anaerobic and anaerobic conditions. In addition, M. gracile YL28 was able to grow using nitrite as the sole nitrogen source in situations when nitrogen gas produced by denitrification was eliminated. Taken together, the data indicate that M. gracile YL28 performs simultaneous heterotrophic nitrification and denitrification at low-DO levels and uses nitrite as the sole nitrogen source for growth. Our study is the first to demonstrate that anoxygenic phototrophic bacteria perform heterotrophic ammonia-oxidization and denitrification under anaerobic conditions.

  13. Formation of Hydride-Meisenheimer Complexes of Picric Acid (2,4,6-Trinitrophenol) and 2,4-Dinitrophenol during Mineralization of Picric Acid by Nocardioides sp. Strain CB 22-2

    PubMed Central

    Behrend, Christian; Heesche-Wagner, Kerstin

    1999-01-01

    There are only a few examples of microbial conversion of picric acid (2,4,6-trinitrophenol). None of the organisms that have been described previously is able to use this compound as a sole source of carbon, nitrogen, and energy at high rates. In this study we isolated and characterized a strain, strain CB 22-2, that was able to use picric acid as a sole source of carbon and energy at concentrations up to 40 mM and at rates of 1.6 mmol · h−1 · g (dry weight) of cells−1 in continuous cultures and 920 μmol · h−1 · g (dry weight) of cells−1 in flasks. In addition, this strain was able to use picric acid as a sole source of nitrogen at comparable rates in a nitrogen-free medium. Biochemical characterization and 16S ribosomal DNA analysis revealed that strain CB 22-2 is a Nocardioides sp. strain. High-pressure liquid chromatography and UV-visible light data, the low residual chemical oxygen demand, and the stoichiometric release of 2.9 ± 0.1 mol of nitrite per mol of picric acid provided strong evidence that complete mineralization of picric acid occurred. During transformation, the metabolites detected in the culture supernatant were the [H−]-Meisenheimer complexes of picric acid and 2,4-dinitrophenol (H−-DNP), as well as 2,4-dinitrophenol. Experiments performed with crude extracts revealed that H−-DNP formation indeed is a physiologically relevant step in picric acid metabolism. PMID:10103224

  14. Functional Characterization of Alanine Racemase from Schizosaccharomyces pombe: a Eucaryotic Counterpart to Bacterial Alanine Racemase

    PubMed Central

    Uo, Takuma; Yoshimura, Tohru; Tanaka, Naotaka; Takegawa, Kaoru; Esaki, Nobuyoshi

    2001-01-01

    Schizosaccharomyces pombe has an open reading frame, which we named alr1+, encoding a putative protein similar to bacterial alanine racemase. We cloned the alr1+ gene in Escherichia coli and purified the gene product (Alr1p), with an Mr of 41,590, to homogeneity. Alr1p contains pyridoxal 5′-phosphate as a coenzyme and catalyzes the racemization of alanine with apparent Km and Vmax values as follows: for l-alanine, 5.0 mM and 670 μmol/min/mg, respectively, and for d-alanine, 2.4 mM and 350 μmol/min/mg, respectively. The enzyme is almost specific to alanine, but l-serine and l-2-aminobutyrate are racemized slowly at rates 3.7 and 0.37% of that of l-alanine, respectively. S. pombe uses d-alanine as a sole nitrogen source, but deletion of the alr1+ gene resulted in retarded growth on the same medium. This indicates that S. pombe has catabolic pathways for both enantiomers of alanine and that the pathway for l-alanine coupled with racemization plays a major role in the catabolism of d-alanine. Saccharomyces cerevisiae differs markedly from S. pombe: S. cerevisiae uses l-alanine but not d-alanine as a sole nitrogen source. Moreover, d-alanine is toxic to S. cerevisiae. However, heterologous expression of the alr1+ gene enabled S. cerevisiae to grow efficiently on d-alanine as a sole nitrogen source. The recombinant yeast was relieved from the toxicity of d-alanine. PMID:11244061

  15. BWR ASSEMBLY SOURCE TERMS FOR WASTE PACKAGE DESIGN

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    T.L. Lotz

    1997-02-15

    This analysis is prepared by the Mined Geologic Disposal System (MGDS) Waste Package Development Department (WPDD) to provide boiling water reactor (BWR) assembly radiation source term data for use during Waste Package (WP) design. The BWR assembly radiation source terms are to be used for evaluation of radiolysis effects at the WP surface, and for personnel shielding requirements during assembly or WP handling operations. The objectives of this evaluation are to generate BWR assembly radiation source terms that bound selected groupings of BWR assemblies, with regard to assembly average burnup and cooling time, which comprise the anticipated MGDS BWR commercialmore » spent nuclear fuel (SNF) waste stream. The source term data is to be provided in a form which can easily be utilized in subsequent shielding/radiation dose calculations. Since these calculations may also be used for Total System Performance Assessment (TSPA), with appropriate justification provided by TSPA, or radionuclide release rate analysis, the grams of each element and additional cooling times out to 25 years will also be calculated and the data included in the output files.« less

  16. Low-threshold, CW, all-solid-state Ti:Al2O3 laser

    NASA Technical Reports Server (NTRS)

    Harrison, James; Finch, Andrew; Rines, David M.; Rines, Glen A.; Moulton, Peter F.

    1991-01-01

    A CW Ti:Al2O3 ring laser with a threshold power of 119 mW is demonstrated. It provides a tunable source of single-frequency, diffraction-limited radiation that is suitable for injection seeding. The Ti:Al2O3 laser is operated with a diode-laser-pumped, frequency-doubled, Nd:YAG laser as the sole pump source.

  17. Safe arming system for two-explosive munitions

    DOEpatents

    Jaroska, Miles F.; Niven, William A.; Morrison, Jasper J.

    1978-01-01

    A system for safely and positively detonating high-explosive munitions, including a source of electrical signals, a split-phase square-loop transformer responsive solely to a unique series of signals from the source for charging an energy storage circuit through a voltage doubling circuit, and a spark-gap trigger for initiating discharge of the energy in the storage circuit to actuate a detonator and thereby fire the munitions.

  18. Soy protein isolate protects against ethanol mediated tumor progression in diethylnitrosamine treated male mice

    USDA-ARS?s Scientific Manuscript database

    In this study, DEN-treated male mice were assigned to 3 groups: a 35% high fat ethanol liquid diet (EtOH) with casein as the protein source, the same EtOH liquid diet with soy protein isolate as the sole protein source (EtOH/soy) and a chow group. EtOH feeding continued for 16 wks. As expected, E...

  19. The Tell-Tale: What Do Heart Rate; Skin Temperature and Skin Conductance Reveal about Emotions of People with Severe and Profound Intellectual Disabilities?

    ERIC Educational Resources Information Center

    Vos, Pieter; De Cock, Paul; Munde, Vera; Petry, Katja; Van Den Noortgate, Wim; Maes, Bea

    2012-01-01

    Identifying emotions in people with severe and profound intellectual disabilities is a difficult challenge. Since self-reports are not available, behaviour is the most used source of information. Given the limitations and caveats associated with using behaviour as the sole source of information about their emotions, it is important to supplement…

  20. 46 CFR 112.30-1 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-1 General. This subpart contains requirements applicable to emergency power installations having...

  1. 46 CFR 112.30-1 - General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-1 General. This subpart contains requirements applicable to emergency power installations having...

  2. 46 CFR 112.30-1 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-1 General. This subpart contains requirements applicable to emergency power installations having...

  3. 46 CFR 112.30-1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-1 General. This subpart contains requirements applicable to emergency power installations having...

  4. 46 CFR 112.30-1 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-1 General. This subpart contains requirements applicable to emergency power installations having...

  5. 78 FR 13860 - Application(s) for Duty-Free Entry of Scientific Instruments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-01

    ... human diseases including cancer, cardiovascular disease, immunodeficiency and dementia. Justification... organism levels. The data will be used to improve management of human diseases including cancer, cardiovascular disease, immunodeficiency and dementia. Justification for Duty-Free Entry: There are no...

  6. Inoculating against Pro-Plagiarism Justifications: Rational and Affective Strategies

    ERIC Educational Resources Information Center

    Compton, Josh; Pfau, Michael

    2008-01-01

    Student plagiarism continues to threaten academic integrity. This investigation assessed whether an inoculation message strategy could combat university plagiarism by protecting student attitudes against pro-plagiarism justification arguments. Additionally, we sought theoretical confirmation of previous findings on involvement and accessibility in…

  7. 48 CFR 606.304 - Approval of the justification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Approval of the justification. 606.304 Section 606.304 Federal Acquisition Regulations System DEPARTMENT OF STATE COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 606.304...

  8. 16 CFR 1702.7 - Justification for the exemption.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Justification for the exemption. 1702.7 Section 1702.7 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION POISON PREVENTION PACKAGING ACT OF 1970 REGULATIONS PETITIONS FOR EXEMPTIONS FROM POISON PREVENTION PACKAGING ACT REQUIREMENTS; PETITION...

  9. 16 CFR 1702.7 - Justification for the exemption.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Justification for the exemption. 1702.7 Section 1702.7 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION POISON PREVENTION PACKAGING ACT OF 1970 REGULATIONS PETITIONS FOR EXEMPTIONS FROM POISON PREVENTION PACKAGING ACT REQUIREMENTS; PETITION...

  10. 16 CFR 1702.7 - Justification for the exemption.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Justification for the exemption. 1702.7 Section 1702.7 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION POISON PREVENTION PACKAGING ACT OF 1970 REGULATIONS PETITIONS FOR EXEMPTIONS FROM POISON PREVENTION PACKAGING ACT REQUIREMENTS; PETITION...

  11. 16 CFR 1702.7 - Justification for the exemption.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Justification for the exemption. 1702.7 Section 1702.7 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION POISON PREVENTION PACKAGING ACT OF 1970 REGULATIONS PETITIONS FOR EXEMPTIONS FROM POISON PREVENTION PACKAGING ACT REQUIREMENTS; PETITION...

  12. Health Care Professionals' Attitudes About Physician-Assisted Death: An Analysis of Their Justifications and the Roles of Terminology and Patient Competency.

    PubMed

    Braverman, Derek W; Marcus, Brian S; Wakim, Paul G; Mercurio, Mark R; Kopf, Gary S

    2017-10-01

    Health care professionals (HCPs) are crucial to physician-assisted death (PAD) provision. To quantitatively assess the favorability of justifications for or against PAD legalization among HCPs, the effect of the terms "suicide" and "euthanasia" on their views and their support for three forms of PAD. Our questionnaire presented three cases: physician-assisted suicide, euthanasia for a competent patient, and euthanasia for an incompetent patient with an advance directive for euthanasia. Respondents judged whether each case was ethical and should be legal and selected their justifications from commonly cited reasons. The sample included physician clinicians, researchers, nonphysician clinicians, and other nonclinical staff at a major academic medical center. Of 221 HCPs, the majority thought that each case was ethical and should be legal. In order of declining favorability, justifications supporting PAD legalization were relief of suffering, right to die, mercy, acceptance of death, nonabandonment, and saving money for the health care system; opposing justifications were the slippery slope argument, unnecessary due to palliative care, killing patients is wrong, religious views, and suicide is wrong. The use of suicide and euthanasia terminology did not affect responses. Participants preferred physician-assisted suicide to euthanasia for a competent patient (P < 0.0001) and euthanasia for an incompetent patient to euthanasia for a competent patient (P < 0.005). HCPs endorsed patient-centered justifications over other reasons, including role-specific duties. Suicide and euthanasia language did not bias HCPs against PAD, challenging claims that such value-laden terms hinder dialogue. More research is required to understand the significance of competency in shaping attitudes toward PAD. Published by Elsevier Inc.

  13. An examination of domestic partner violence and its justification in the Republic of Georgia

    PubMed Central

    2013-01-01

    Background Little research on Intimate Partner Violence (IPV) and social perceptions toward this behavior has been disseminated from Eastern Europe. This study explores the prevalence and risk factors of IPV and the justification of this behavior among women in the Republic of Georgia. It seeks to better understand how IPV and IPV justification relate and how social justification of IPV differs across socio-economic measures among this population of women. Methods This study utilizes a national sample of ever-married women from the Republic of Georgia (N = 4,302). We describe the factors that predict IPV justification among these women and the relationship between of the acceptability of IPV and victimization overall and across socio-demographic factors. Results While the overall lifetime prevalence of IPV in this sample was relatively low (4%), these women were two to four times more likely to justify IPV, Just under one-quarter of the sample agreed that IPV was justified in at least one scenario, namely when the wife was unfaithful, compared with women who had no experience being abused by a partner. Georgian women who were poor, from a rural community, had lower education, were not working and who experienced child abuse or IPV among their parents were more likely to justify this behavior. Conclusions These findings begin to fill a gap in our understanding of IPV experienced by women in Eastern Europe. In addition, these findings emphasize the need for researchers, practitioners and policy makers to contextualize IPV in terms of the justification of this behavior among the population being considered as this can play an important role in perpetration, victimization and response. PMID:24180483

  14. 13 CFR 130.460 - Budget justification.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Budget justification. 130.460 Section 130.460 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS DEVELOPMENT... in the normal course of Program administration, and conform to the written travel policies of the...

  15. 28 CFR 570.32 - Justification for furlough.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Justification for furlough. 570.32 Section 570.32 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE COMMUNITY PROGRAMS AND... plans; (3) To reestablish family and community ties; (4) To participate in selected educational, social...

  16. 48 CFR 6.305 - Availability of the justification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 6.305 Availability of the... contractor proprietary data and remove all such data, and such references and citations as are necessary to protect the proprietary data, before making the justifications available for public inspection...

  17. 48 CFR 6.305 - Availability of the justification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 6.305 Availability of the... contractor proprietary data and remove all such data, and such references and citations as are necessary to protect the proprietary data, before making the justifications available for public inspection...

  18. 48 CFR 6.305 - Availability of the justification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 6.305 Availability of the... contractor proprietary data and remove all such data, and such references and citations as are necessary to protect the proprietary data, before making the justifications available for public inspection...

  19. 48 CFR 6.305 - Availability of the justification.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 6.305 Availability of the... contractor proprietary data and remove all such data, and such references and citations as are necessary to protect the proprietary data, before making the justifications available for public inspection...

  20. 48 CFR 6.305 - Availability of the justification.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 6.305 Availability of the... contractor proprietary data and remove all such data, and such references and citations as are necessary to protect the proprietary data, before making the justifications available for public inspection...

  1. Progress in Modeling Nonlinear Dendritic Evolution in Two and Three Dimensions, and Its Mathematical Justification

    NASA Technical Reports Server (NTRS)

    Tanveer, S.; Foster, M. R.

    2002-01-01

    We report progress in three areas of investigation related to dendritic crystal growth. Those items include: 1. Selection of tip features dendritic crystal growth; 2) Investigation of nonlinear evolution for two-sided model; and 3) Rigorous mathematical justification.

  2. 30 CFR 700.12 - Petitions to initiate rulemaking.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... statement of the facts, technical justification, and law which require issuance, amendment, or repeal of a... of the petition, the Director shall determine if the petition sets forth facts, technical.... Facts, technical justification or law previously considered in a petition or rulemaking on the same...

  3. Justification of Paternalism in Education.

    ERIC Educational Resources Information Center

    Nordenbo, Sven Erik

    1986-01-01

    A systematic presentation is given of the theories of justification normally applied to paternalistic acts: (1) pseudo-paternalism, (2) consequentialism, and (3) consent-based theories. The validity of four common arguments for educational paternalism is discussed: education is necessary, children are ignorant, children are unable to choose, and…

  4. 48 CFR 6.304 - Approval of the justification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Approval of the justification. 6.304 Section 6.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 6.304 Approval of the...

  5. 48 CFR 1306.304 - Approval of the justification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... justification. 1306.304 Section 1306.304 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 1306.304... open competition at the dollar thresholds in FAR 6.304 is set forth in CAM 1301.70. ...

  6. 48 CFR 1406.304 - Approval of the justification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Approval of the justification. 1406.304 Section 1406.304 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 1406.304...

  7. 48 CFR 906.304 - Approval of the justification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Approval of the justification. 906.304 Section 906.304 Federal Acquisition Regulations System DEPARTMENT OF ENERGY COMPETITION ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 906.304 Approval of the...

  8. Appealing to the crowd: ethical justifications in Canadian medical crowdfunding campaigns.

    PubMed

    Snyder, Jeremy; Crooks, Valorie A; Mathers, Annalise; Chow-White, Peter

    2017-06-01

    Medical crowdfunding is growing in terms of the number of active campaigns, amount of funding raised and public visibility. Little is known about how campaigners appeal to potential donors outside of anecdotal evidence collected in news reports on specific medical crowdfunding campaigns. This paper offers a first step towards addressing this knowledge gap by examining medical crowdfunding campaigns for Canadian recipients. Using 80 medical crowdfunding campaigns for Canadian recipients, we analyse how Canadians justify to others that they ought to contribute to funding their health needs. We find the justifications campaigners tend to fall into three themes: personal connections, depth of need and giving back. We further discuss how these appeals can understood in terms of ethical justifications for giving and how these justifications should be assessed in light of the academic literature on ethical concerns raised by medical crowdfunding. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  9. On Engster's care-justification of the specialness thesis about healthcare.

    PubMed

    Rumbold, Benedict

    2017-08-01

    To say health is 'special' is to say that it has a moral significance that differentiates it from other goods (cars, say or radios) and, as a matter of justice, warrants distributing it separately. In this essay, I critique a new justification for the specialness thesis about healthcare (STHC) recently put forth by Engster. I argue that, regrettably, Engster's justification of STHC ultimately fails and fails on much the same grounds as have previous justifications of STHC. However, I also argue that Engster's argument still adds something valuable to the debate around STHC insofar as it reminds us that the moral significance of healthcare may be wider than simply its effect on the incidence of disability and disease: one further reason we may think healthcare is morally significant is because it concerns the treatment and care of those who are already unwell. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  10. Justification beliefs of violence, myths about love and cyber dating abuse.

    PubMed

    Borrajo, Erika; Gámez-Guadix, Manuel; Calvete, Esther

    2015-01-01

    Distorted beliefs about violence and love are often associated with the presence of violence in dating relationships. This study analyzes the relationship between beliefs that justify violence and myths about love in two types of cyber dating abuse (control and direct aggression). The sample consisted of 656 young people between the ages of 18 and 30 years (79.5% women). Regression analysis showed that justification of cyber dating abuse was significantly associated with a higher likelihood of direct aggression in online dating relationships. Myths about love were associated with a greater likelihood of control in online dating relationships. Furthermore, the relationship between justification of cyber dating abuse and perpetration of direct aggression was stronger in women. The relationship between myths about love and perpetration of online control was stronger among the youngest individuals. The justification of abuse and myths about love are important aspects in the development of different kinds of online abuse among young couples. This finding has important implications for the prevention of and intervention in these behaviors.

  11. Exposure to benevolent sexism and complementary gender stereotypes: consequences for specific and diffuse forms of system justification.

    PubMed

    Jost, John T; Kay, Aaron C

    2005-03-01

    Many have suggested that complementary gender stereotypes of men as agentic (but not communal) and women as communal (but not agentic) serve to increase system justification, but direct experimental support has been lacking. The authors exposed people to specific types of gender-related beliefs and subsequently asked them to complete measures of gender-specific or diffuse system justification. In Studies 1 and 2, activating (a) communal or complementary (communal + agentic) gender stereotypes or (b) benevolent or complementary (benevolent + hostile) sexist items increased support for the status quo among women. In Study 3, activating stereotypes of men as agentic also increased system justification among men and women, but only when women's characteristics were associated with higher status. Results suggest that complementary stereotypes psychologically offset the one-sided advantage of any single group and contribute to an image of society in which everyone benefits through a balanced dispersion of benefits. ((c) 2005 APA, all rights reserved).

  12. Reducing duplicate testing: a comparison of two clinical decision support tools.

    PubMed

    Procop, Gary W; Keating, Catherine; Stagno, Paul; Kottke-Marchant, Kandice; Partin, Mary; Tuttle, Robert; Wyllie, Robert

    2015-05-01

    Unnecessary duplicate laboratory testing is common and costly. Systems-based means to avert unnecessary testing should be investigated and employed. We compared the effectiveness and cost savings associated with two clinical decision support tools to stop duplicate testing. The Hard Stop required telephone contact with the laboratory and justification to have the duplicate test performed, whereas the Smart Alert allowed the provider to bypass the alert at the point of order entry without justification. The Hard Stop alert was significantly more effective than the Smart Alert (92.3% vs 42.6%, respectively; P < .0001). The cost savings realized per alert activation was $16.08/alert for the Hard Stop alert vs $3.52/alert for the Smart Alert. Structural and process changes that require laboratory contact and justification for duplicate testing are more effective than interventions that allow providers to bypass alerts without justification at point of computerized physician order entry. Copyright© by the American Society for Clinical Pathology.

  13. Test Equal Bending by Gravity for Space and Time

    NASA Astrophysics Data System (ADS)

    Sweetser, Douglas

    2009-05-01

    For the simplest problem of gravity - a static, non-rotating, spherically symmetric source - the solution for spacetime bending around the Sun should be evenly split between time and space. That is true to first order in M/R, and confirmed by experiment. At second order, general relativity predicts different amounts of contribution from time and space without a physical justification. I show an exponential metric is consistent with light bending to first order, measurably different at second order. All terms to all orders show equal contributions from space and time. Beautiful minimalism is Nature's way.

  14. Cogeneration and beyond: The need and opportunity for high efficiency, renewable community energy systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gleason, T.C.J.

    1992-06-01

    The justification, strategies, and technology options for implementing advanced district heating and cooling systems in the United States are presented. The need for such systems is discussed in terms of global warming, ozone depletion, and the need for a sustainable energy policy. Strategies for implementation are presented in the context of the Public Utilities Regulatory Policies Act and proposed new institutional arrangements. Technology opportunities are highlighted in the areas of advanced block-scale cogeneration, CFC-free chiller technologies, and renewable sources of heating and cooling that are particularly applicable to district systems.

  15. A Case for Crowd Sourcing in Stem Cell Research

    PubMed Central

    Mummery, Christine L.; Rabelink, Ton J.

    2014-01-01

    SUMMARY Thousands of patients and placebo-treated controls have been included in many clinical trials of stem cell therapy over the last decade or so, but often the study groups have been small. Their scientific value may therefore be limited and their ethical justification questionable. Would “crowd sourcing” for data sharing be a means of increasing the collective value of clinical trials? Here, we make a case for open access of all data emerging from stem cell studies (trials but also observational studies) independent of whether they are investigator-initiated or commercially driven. PMID:25232185

  16. 46 CFR 112.35-1 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS... Generator as the Sole Emergency Power Source § 112.35-1 General. This subpart contains requirements applicable to emergency power installations having a manually controlled storage battery, diesel engine, or...

  17. 46 CFR 112.35-1 - General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS... Generator as the Sole Emergency Power Source § 112.35-1 General. This subpart contains requirements applicable to emergency power installations having a manually controlled storage battery, diesel engine, or...

  18. 46 CFR 112.35-1 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS... Generator as the Sole Emergency Power Source § 112.35-1 General. This subpart contains requirements applicable to emergency power installations having a manually controlled storage battery, diesel engine, or...

  19. Novel nuclear-cytoplasmic interaction in wheat (Triticum aestivum) induces vigorous plants

    USDA-ARS?s Scientific Manuscript database

    Interspecific hybridization can be considered an accelerator of evolution, otherwise a slow process, solely dependent on mutation and recombination. Upon interspecific hybridization, several novel interactions between nuclear and cytoplasmic genomes emerge which provide additional sources of diversi...

  20. 48 CFR 819.7008 - Sole source awards to veteran-owned small business concerns.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... determined to be a responsible contractor with respect to performance; (4) Award can be made at a fair and... businesses are registered and verified as eligible in the VIP database prior to making an award. ...

  1. Cultivating Parabolas in the Parlor Garden: Reconciling Mathematics Education and Feminine Ideals in Nineteenth-Century America

    NASA Astrophysics Data System (ADS)

    Fiss, Andrew

    2014-02-01

    This article introduces the justification problem for mathematics, which it explores through the case study of 1820s-1840s rationales for the teaching of mathematics to women in the United States. It argues that, while educators in the 1820s justified women's studies through mental discipline (a common reason for men's study), those of the 1830s-1840s increasingly relied on separate, gendered justifications, tied to emerging ideals of middle-class femininity. This article therefore emphasizes the contingency of the justification problem, which serves to break the present-day cycle of gender stereotypes regarding mathematics.

  2. Medically Inappropriate or Futile Treatment: Deliberation and Justification 1

    PubMed Central

    Misak, Cheryl J.; White, Douglas B.; Truog, Robert D.

    2016-01-01

    This paper reframes the futility debate, moving away from the question “Who decides when to end what is considered to be a medically inappropriate or futile treatment?” and toward the question “How can society make policy that will best account for the multitude of values and conflicts involved in such decision-making?” It offers a pragmatist moral epistemology that provides us with (1) a clear justification of why it is important to take best standards, norms, and physician judgment seriously and (2) a clear justification of why ample opportunity must be made for patients, families, and society to challenge those standards and norms. PMID:26681796

  3. Induction of L-phenylalanine ammonia-lyase during utilization of phenylalanine as a carbon or nitrogen source in Rhodotorula glutinis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marusich, W.C.; Jensen, R.A.; Zamir, L.O.

    Rhodotorula glutinis is a convenient source of L-phenylalanine ammonia-lyase, an enzyme that is useful as a biochemical reagent in the assay of L-phenylalanine. There have been previous descriptions of induced lyase production in complex medium where induction occurs late in exponential growth, suggesting a role in secondary metabolism such as is the case in higher plants. A higher specific activity of L-phenylalanine ammonia-lyase (sixfold higher than in complex medium) can be obtained during midexponential growth in a defined medium containing L-phenylalanine as the sole source of carbon. L-phenylalanine will also induce lyase synthesis during exponential growth in minimal medium inmore » which L-phenylalanine is the sole source of nitrogen. The appearance of lyase in complex medium supplemented with L-phenylalanine is probably triggered fortuitously by exhaustion late in growth of a prime source of nitrogen. In this study, R. glutinis appeared to express a single lyase enzyme, regardless of whether induction was nitrogen signaled or carbon signaled. Thin-layer chromatographic analysis of ether extracts prepared fom cultures induced with doubly labeled (U-/sup 14/C; ring-4-/sup 3/H) L-phenylalanine provided evidence of a catabolic sequence containing cinnamic acid, benzoic acid, and 4-hydroxybenzoic acid as degradative intermediates. 3,4-Dihydroxybenzoic acid was not identified as a catabolic intermediate.« less

  4. Induction of L-phenylalanine ammonia-lyase during utilization of phenylalanine as a carbon or nitrogen source in Rhodotorula glutinis.

    PubMed Central

    Marusich, W C; Jensen, R A; Zamir, L O

    1981-01-01

    Rhodotorula glutinis is a convenient source of L-phenylalanine ammonia-lyase, an enzyme that is useful as a biochemical reagent in the assay of L-phenylalanine. There have been previous descriptions of induced lyase production in complex medium where induction occurs late in exponential growth, suggesting a role in secondary metabolism such as is the case in higher plants. A higher specific activity of L-phenylalanine ammonia-lyase (sixfold higher than a complex medium) can be obtained during midexponential growth in a defined medium containing L-phenylalanine as the sole source of carbon. L-Phenylalanine will also induce lyase synthesis during exponential growth in minimal in which L-phenylalanine is the sole source of nitrogen. The appearance of lyase in complex medium supplemented with L-phenylalanine is probably triggered fortuitously by exhaustion late in growth of a prime source of nitrogen. In this study, R. glutinis appeared to express a single lyase enzyme, regardless of whether induction was nitrogen signaled or carbon signaled. Thin-layer chromatographic analysis of ether extracts prepared from cultures induced with doubly labeled (U-14C; ring-4-3H) L-phenylalanine provided evidence of a catabolic sequence containing cinnamic acid, benzoic acid, and 4-hydroxybenzoic acid as degradative intermediates. 3,4-Dihydroxybenzoic acid was not identified as a catabolic intermediate. PMID:7195398

  5. 41 CFR 109-26.501-52 - Justification for purchase.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Justification for purchase. 109-26.501-52 Section 109-26.501-52 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT REGULATIONS SUPPLY AND...

  6. Satellite image-based maps: Scientific inference or pretty pictures?

    Treesearch

    Ronald E. McRoberts

    2011-01-01

    The scientific method has been characterized as having two distinct components, Discovery and Justification. Discovery emphasizes ideas and creativity, focuses on conceiving hypotheses and constructing models, and is generally regarded as lacking a formal logic. Justification begins with the hypotheses and models and ends with a...

  7. 16 CFR § 1702.7 - Justification for the exemption.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Justification for the exemption. § 1702.7 Section § 1702.7 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION POISON PREVENTION PACKAGING ACT OF 1970 REGULATIONS PETITIONS FOR EXEMPTIONS FROM POISON PREVENTION PACKAGING ACT REQUIREMENTS...

  8. Autonomy and informed consent: a mistaken association?

    PubMed

    Kristinsson, Sigurdur

    2007-09-01

    For decades, the greater part of efforts to improve regulatory frameworks for research ethics has focused on informed consent procedures; their design, codification and regulation. Why is informed consent thought to be so important? Since the publication of the Belmont Report in 1979, the standard response has been that obtaining informed consent is a way of treating individuals as autonomous agents. Despite its political success, the philosophical validity of this Belmont view cannot be taken for granted. If the Belmont view is to be based on a conception of autonomy that generates moral justification, it will either have to be reinterpreted along Kantian lines or coupled with a something like Mill's conception of individuality. The Kantian interpretation would be a radical reinterpretation of the Belmont view, while the Millian justification is incompatible with the liberal requirement that justification for public policy should be neutral between controversial conceptions of the good. This consequence might be avoided by replacing Mill's conception of individuality with a procedural conception of autonomy, but I argue that the resulting view would in fact fail to support a non-Kantian, autonomy-based justification of informed consent. These difficulties suggest that insofar as informed consent is justified by respect for persons and considerations of autonomy, as the Belmont report maintained, the justification should be along the lines of Kantian autonomy and not individual autonomy.

  9. Justification of diagnostic medical exposures: some practical issues. Report of an International Atomic Energy Agency Consultation

    PubMed Central

    Malone, J; Guleria, R; Craven, C; Horton, P; Järvinen, H; Mayo, J; O’reilly, G; Picano, E; Remedios, D; Le Heron, J; Rehani, M; Holmberg, O; Czarwinski, R

    2012-01-01

    Objectives The Radiation Protection of Patients Unit of the International Atomic Energy Agency (IAEA) is concerned about the effectiveness of justification of diagnostic medical exposures. Recent published work and the report of an initial IAEA consultation in the area gave grounds for such concerns. There is a significant level of inappropriate usage, and, in some cases, a poor level of awareness of dose and risk among some key groups involved. This article aims to address this. Methods The IAEA convened a second group of experts in November 2008 to review practical and achievable actions that might lead to more effective justification. Results This report summarises the matters that this group considered and the outcome of their deliberations. There is a need for improved communication, both within professions and between professionals on one hand, and between professionals and the patients/public on the other. Coupled with this, the issue of consent to imaging procedures was revisited. The need for good evidence-based referral guidelines or criteria of acceptability was emphasised, as was the need for their global adaptation and dissemination. Conclusion Clinical audit was regarded as a key tool in ensuring that justification becomes an effective, transparent and accountable part of normal radiological practice. In summary, justification would be facilitated by the “3 As”: awareness, appropriateness and audit. PMID:21343316

  10. Poly-β-hydroxybutyrate and exopolysaccharide biosynthesis by bacterial isolates from pigeonpea [Cajanus cajan (L.) Millsp] root nodules.

    PubMed

    Fernandes, Paulo Ivan; de Oliveira, Paulo Jansen; Rumjanek, Norma Gouvêa; Xavier, Gustavo Ribeiro

    2011-02-01

    The bacterial strains that are able to produce biopolymers that are applied in industrial sectors present a source of renewable resources. Some microorganisms are already applied at several industrial sectors, but the prospecting of new microbes must bring microorganisms that are feasible to produce interesting biopolymers more efficiently and in cheaper conditions. Among the biopolymers applied industrially, polyhydroxybutyrate (PHB) and exopolysaccharides (EPS) stand out because of its applications, mainly in biodegradable plastic production and in food industry, respectively. In this context, the capacity of bacteria isolated from pigeonpea root nodules to produce EPS and PHB was evaluated, as well as the cultural characterization of these isolates. Among the 38 isolates evaluated, the majority presented fast growth and ability to acidify the culture media. Regarding the biopolymer production, five isolates produced more than 10 mg PHB per liter of culture medium. Six EPS producing bacteria achieved more than 200 mg EPS per liter of culture medium. Evaluating different carbon sources, the PHB productivity of the isolate 24.6b reached 69% of cell dry weight when cultured with starch as sole carbon source, and the isolate 8.1c synthesized 53% PHB in dry cell biomass and more than 1.3 g L⁻¹ of EPS when grown using xylose as sole carbon source.

  11. ICT Student Teachers' Judgments and Justifications about Ethical Issues

    ERIC Educational Resources Information Center

    Alakurt, Turgay; Bardakci, Salih; Keser, Hafize

    2012-01-01

    In this study, Turkish ICT student teachers' judgments and justifications in four scenarios involving ICT-related ethical problems were investigated. Scenarios were designed based on Mason's (1986) four ethical issues: privacy, accuracy, property and accessibility. The study was carried out in the fall of 2010. We used the critical incidents…

  12. Kierkegaard, Justification and the Integrity of Christian Education

    ERIC Educational Resources Information Center

    Wright, Andrew W.

    2015-01-01

    The doctrine of justification is frequently interpreted in a manner that excludes our active involvement in the drama of salvation. This reading has a detrimental effect on Christian education concerned to enable the learner's attentive, reasonable and responsible understanding of the Gospel. Taking its lead from Kierkegaard's account of…

  13. 41 CFR 109-28.5004 - Justification and review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROCUREMENT 28-STORAGE AND DISTRIBUTION 28.50-Management of Equipment Held for Future Projects § 109-28.5004... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Justification and review procedures. 109-28.5004 Section 109-28.5004 Public Contracts and Property Management Federal Property...

  14. Self-Justification as a Determinant of Performance-Style Effectiveness

    ERIC Educational Resources Information Center

    McKenna, Ralph J.

    1971-01-01

    This study examined experimentally the effect of justification on role playing, attempting a more complete verification of the performance style type. Also of concern was whether scores on the Performance Style Test were generalizable to overt behavior on the part of females. Results supported both concerns. (Author/CG)

  15. What Exactly (If Anything) Is Wrong with Paternalism towards Children?

    ERIC Educational Resources Information Center

    Drerup, Johannes

    2017-01-01

    Theoretical and practical issues concerning the justification of paternalism towards children are widely debated in a variety of philosophical contexts. The major focus of these debates lies either on questions concerning the general legitimacy of paternalism towards children or on justifications of paternalism in concrete situations involving…

  16. Cyber Attacks and the Legal Justification for an Armed Response

    DTIC Science & Technology

    2017-05-25

    conflict between military forces of any origin.ൟ The definition above applies only to Title 18, Chapter 113B “ Terrorism ,” and is not applicable...beyond the context of terrorism . Applying this definition to cyber attacks outside the context of terrorism will not provide legal justification for

  17. The Learning Society: Two Justifications

    ERIC Educational Resources Information Center

    Su, Ya-hui

    2010-01-01

    This article examines the view that has long been fashionable in related policies and literature that the establishment of the learning society is a necessary response to changing times. This article suggests that the association between the learning society and current change may be defensible but is limited. The justification of the learning…

  18. Lower Pay for Women's Coaches: Refuting Some Common Justifications.

    ERIC Educational Resources Information Center

    Williams, Joseph P.

    1995-01-01

    The two standard justifications for different salaries paid to male and female coaches under 1963 and 1964 civil rights/equal pay legislation must fail under Title IX of the Education Amendments of 1972, which independently prohibits gender discrimination in employment and mandates equal athletic opportunity for female students. Some suggestions…

  19. 48 CFR 306.304 - Approval of the justification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... justification. 306.304 Section 306.304 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 306.304... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA...

  20. Enacting and Justifying Local Reforms: Implications for Understanding Change in Educational Organizations

    ERIC Educational Resources Information Center

    Krumm, Andrew E.; Holmstrom, Kristi

    2011-01-01

    This article argues that the processes of enactment and justification comprise two key, underdeveloped aspects of sensemaking theory as applied to educational organizations. Enactment and justification are illustrated using examples drawn from a school that significantly changed the way in which it coordinated reading instruction. Examples drawn…

  1. 21 CFR 520.2089 - Roxarsone liquid.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... teaspoon (5 milliliters) to each gallon of drinking water (0.002 percent roxarsone). (2) Indications for... for human consumption. Withdraw 5 days before slaughter. Use as sole source of organic arsenic...

  2. 21 CFR 520.1807 - Piperazine.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... in drinking water or feed. Use as sole source of drinking water. Prepare fresh solution daily. Use as... for human consumption. Consult your veterinarian for assistance in the diagnosis, treatment, and...

  3. RELATIONSHIPS OF NATURAL ENEMIES AND NON-PREY FOODS

    USDA-ARS?s Scientific Manuscript database

    There are very few entomophagous species so maladapted as to rely on prey as their sole nutritional resource. Although a rich source of nutrients, prey/host availability to predators and parasitoids is restricted temporally by ephemeral population dynamics, spatial differences in microclimate, struc...

  4. OBSERVATIONS FROM CONTAMINANT PLUMES ON LONG ISLAND

    EPA Science Inventory

    The aquifers of Long Island serve as a sole source drinking water supply for the entire
    local population of about three million people. Where the shallow Upper Glacial Aquifer has been contaminated with petroleum hydrocarbons and methyl tert-butyl ether (MTBE), intensive site ...

  5. Effect of varying dietary levels of LC-PUFA and vegetable oil sources on performance and fatty acids of Senegalese sole post larvae: puzzling results suggest complete biosynthesis pathway from C18 PUFA to DHA.

    PubMed

    Navarro-Guillén, Carmen; Engrola, Sofia; Castanheira, Filipa; Bandarra, Narcisa; Hachero-Cruzado, Ismael; Tocher, Douglas R; Conceição, Luís E C; Morais, Sofia

    2014-01-01

    Lipid nutrition of marine fish larvae has focused on supplying essential fatty acids (EFA) at high levels to meet requirements for survival, growth and development. However, some deleterious effects have been reported suggesting that excessive supply of EFA might result in insufficient supply of energy substrates, particularly in species with lower EFA requirements such as Senegalese sole (Solea senegalensis). This study addressed how the balance between EFA and non-EFA (better energy sources) affects larval performance, body composition and metabolism and retention of DHA, by formulating enrichment emulsions containing two different vegetable oil sources (olive oil or soybean oil) and three DHA levels. DHA positively affected growth and survival, independent of oil source, confirming that for sole post-larvae it is advantageous to base enrichments on vegetable oils supplying higher levels of energy, and supplement these with a DHA-rich oil. In addition, body DHA levels were generally comparable considering the large differences in their dietary supply, suggesting that the previously reported ∆4 fatty acyl desaturase (fad) operates in vivo and that DHA was synthesized at physiologically significant rates through a mechanism involving transcriptional up-regulation of ∆4fad, which was significantly up-regulated in the low DHA treatments. Furthermore, data suggested that DHA biosynthesis may be regulated by an interaction between dietary n-3 and n-6 PUFA, as well as by levels of LC-PUFA, and this may, under certain nutritional conditions, lead to DHA production from C18 precursors. The molecular basis of putative fatty acyl ∆5 and ∆6 desaturation activities remains to be fully determined as thorough searches have found only a single (∆4) Fads2-type transcript. Therefore, further studies are required but this might represent a unique activity described within vertebrate fads. © 2013.

  6. Generation and Phenotypic Characterization of Aspergillus nidulans Methylisocitrate Lyase Deletion Mutants: Methylisocitrate Inhibits Growth and Conidiation

    PubMed Central

    Brock, Matthias

    2005-01-01

    Propionate is a very abundant carbon source in soil, and many microorganisms are able to use this as the sole carbon source. Nevertheless, propionate not only serves as a carbon source for filamentous fungi but also acts as a preservative when added to glucose containing media. To solve this contradiction between carbon source and preservative effect, propionate metabolism of Aspergillus nidulans was studied and revealed the methylcitrate cycle as the responsible pathway. Methylisocitrate lyase is one of the key enzymes of that cycle. It catalyzes the cleavage of methylisocitrate into succinate and pyruvate and completes the α-oxidation of propionate. Previously, methylisocitrate lyase was shown to be highly specific for the substrate (2R,3S)-2-methylisocitrate. Here, the identification of the genomic sequence of the corresponding gene and the generation of deletion mutants is reported. Deletion mutants did not grow on propionate as sole carbon and energy source and were severely inhibited during growth on alternative carbon sources, when propionate was present. The strongest inhibitory effect was observed, when glycerol was the main carbon source, followed by glucose and acetate. In addition, asexual conidiation was strongly impaired in the presence of propionate. These effects might be caused by competitive inhibition of the NADP-dependent isocitrate dehydrogenase, because the Ki of (2R,3S)-2-methylisocitrate, the product of the methylcitrate cycle, on NADP-dependent isocitrate dehydrogenase was determined as 1.55 μM. Other isomers had no effect on enzymatic activity. Therefore, methylisocitrate was identified as a potential toxic compound for cellular metabolism. PMID:16151139

  7. Characteristics of Qualitative Descriptive Studies: A Systematic Review

    PubMed Central

    Kim, Hyejin; Sefcik, Justine S.; Bradway, Christine

    2016-01-01

    Qualitative description (QD) is a term that is widely used to describe qualitative studies of health care and nursing-related phenomena. However, limited discussions regarding QD are found in the existing literature. In this systematic review, we identified characteristics of methods and findings reported in research articles published in 2014 whose authors identified the work as QD. After searching and screening, data were extracted from the sample of 55 QD articles and examined to characterize research objectives, design justification, theoretical/philosophical frameworks, sampling and sample size, data collection and sources, data analysis, and presentation of findings. In this review, three primary findings were identified. First, despite inconsistencies, most articles included characteristics consistent with limited, available QD definitions and descriptions. Next, flexibility or variability of methods was common and desirable for obtaining rich data and achieving understanding of a phenomenon. Finally, justification for how a QD approach was chosen and why it would be an appropriate fit for a particular study was limited in the sample and, therefore, in need of increased attention. Based on these findings, recommendations include encouragement to researchers to provide as many details as possible regarding the methods of their QD study so that readers can determine whether the methods used were reasonable and effective in producing useful findings. PMID:27686751

  8. Childhood bereavement services: a survey of UK provision.

    PubMed

    Rolls, L; Payne, S

    2003-07-01

    The purpose of the study was to identify the location, range and type of childhood bereavement service provision in the UK. A questionnaire was mailed to 127 services who were either solely dedicated to childhood bereavement or who offered a service within the range of work of a host organization and for which there was a supporting organizational structure. Responses were received from 108 services (a response rate of 85%). The findings identified that 85% of childhood bereavement services are located in the voluntary sector; 14% are dedicated childhood bereavement services, while 86% are offered as part of a host organization. Forty-four per cent of host organizations are hospices. The majority of services (73%) relied on both paid and unpaid staff, with 11% relying entirely on paid staff and 14% of services relying entirely on unpaid staff. The interventions offered ranged from individual family work (86%), individual child work (62%), groupwork with families (53%) and groupwork with children (45%). In addition, services offered prebereavement support (64%), a 'drop-in' service (17%), information and advice (95%), training (32%) and the provision of resources (88%). As well as offering a service to children and their families, 74% of childhood bereavement services provided a service to 'secondary users', such as schools (66%), the emergency services (28%) and other professionals (63%). In terms of funding, 12% of services relied solely on external sources of funding, including donations, legacies, revenue from the host organization or grants, while 12% of services relied solely on internal sources of funding, including fundraising and training. The majority of services (73%), however, gained income from a range of sources. The study identifies the diversity of provision that has implications for the evaluation of childhood bereavement services.

  9. Two pectin lyase genes, pnl-1 and pnl-2, from Colletotrichum gloeosporioides f. sp. malvae differ in a cellulose-binding domain and in their expression during infection of Malva pusilla.

    PubMed

    Wei, Yangdou; Shih, Jenny; Li, Jieran; Goodwin, Paul H

    2002-07-01

    Two pectin lyase genes, designated pnl-1 and pnl-2, were cloned from Colletotrichum gloeosporioides f. sp. malvae, a pathogen of round-leaved mallow (Malva pusilla). pnl-1 was isolated using cDNA from infected plant material; pnl-2 was isolated using cDNA from 3-day-old mycelia grown in mallow-cell-wall extract (MCWE) broth. pnl-1 is the first pectinase gene described thus far to encode a cellulose-binding domain (CBD), which is common in cellulases and xylanases, whereas pnl-2 encodes a pectin lyase that lacks a CBD. In pure culture, pnl-1 expression could be detected when purified pectin or glucose was the sole carbon source, but not when MCWE was the sole carbon source. The lack of pnl-1 expression appeared to be due to gene repression by some unknown factor(s) in the cell-wall extract. In contrast, expression of pnl-2 was detected in cultures when MCWE, but not when purified pectin or glucose, was the sole carbon source. In infected tissue, detection of pnl-1 expression by Northern-blot hybridization and by RT-PCR began with the onset of the necrotrophic phase of infection. Expression ofpnl-2 was not detectable by Northern-blot hybridization, but was observed byRT-PCR in both the biotrophic and necrotrophic phases of infection. The differences between pnl-1 and pnl-2 (i.e. pnl-1 encoding a CBD and differences in the expression patterns of both genes) may be related to the requirements of C. gloeosporioides f. sp. malvae to be able to grow in host tissue under the different conditions present during the biotrophic and necrotrophic phases of infection.

  10. Biodegradation of the Organic Disulfide 4,4′-Dithiodibutyric Acid by Rhodococcus spp.

    PubMed Central

    Khairy, Heba; Wübbeler, Jan Hendrik

    2015-01-01

    Four Rhodococcus spp. exhibited the ability to use 4,4′-dithiodibutyric acid (DTDB) as a sole carbon source for growth. The most important step for the production of a novel polythioester (PTE) using DTDB as a precursor substrate is the initial cleavage of DTDB. Thus, identification of the enzyme responsible for this step was mandatory. Because Rhodococcus erythropolis strain MI2 serves as a model organism for elucidation of the biodegradation of DTDB, it was used to identify the genes encoding the enzymes involved in DTDB utilization. To identify these genes, transposon mutagenesis of R. erythropolis MI2 was carried out using transposon pTNR-TA. Among 3,261 mutants screened, 8 showed no growth with DTDB as the sole carbon source. In five mutants, the insertion locus was mapped either within a gene coding for a polysaccharide deacetyltransferase, a putative ATPase, or an acetyl coenzyme A transferase, 1 bp upstream of a gene coding for a putative methylase, or 176 bp downstream of a gene coding for a putative kinase. In another mutant, the insertion was localized between genes encoding a putative transcriptional regulator of the TetR family (noxR) and an NADH:flavin oxidoreductase (nox). Moreover, in two other mutants, the insertion loci were mapped within a gene encoding a hypothetical protein in the vicinity of noxR and nox. The interruption mutant generated, R. erythropolis MI2 noxΩtsr, was unable to grow with DTDB as the sole carbon source. Subsequently, nox was overexpressed and purified, and its activity with DTDB was measured. The specific enzyme activity of Nox amounted to 1.2 ± 0.15 U/mg. Therefore, we propose that Nox is responsible for the initial cleavage of DTDB into 2 molecules of 4-mercaptobutyric acid (4MB). PMID:26407888

  11. Burning of liquid pools in reduced gravity

    NASA Technical Reports Server (NTRS)

    Kanury, A. M.

    1977-01-01

    The existing literature on the combustion of liquid fuel pools is reviewed to identify the physical and chemical aspects which require an improved understanding. Among the pre-, trans- and post-ignition processes, a delineation was made of those which seem to uniquely benefit from studies in the essential environment offered by spacelab. The role played by the gravitational constant in analytical and experimental justifications was developed. The analytical justifications were based on hypotheses, models and dimensional analyses whereas the experimental justifications were based on an examination of the range of gravity and gravity-dependent variables possible in the earth-based laboratories. Some preliminary expositions into the questions of feasibility of the proposed spacelab experiment are also reported.

  12. Idleness aversion and the need for justifiable busyness.

    PubMed

    Hsee, Christopher K; Yang, Adelle X; Wang, Liangyan

    2010-07-01

    There are many apparent reasons why people engage in activity, such as to earn money, to become famous, or to advance science. In this report, however, we suggest a potentially deeper reason: People dread idleness, yet they need a reason to be busy. Accordingly, we show in two experiments that without a justification, people choose to be idle; that even a specious justification can motivate people to be busy; and that people who are busy are happier than people who are idle. Curiously, this last effect is true even if people are forced to be busy. Our research suggests that many purported goals that people pursue may be merely justifications to keep themselves busy.

  13. Electrolytic photodissociation of chemical compounds by iron oxide electrodes

    DOEpatents

    Somorjai, Gabor A.; Leygraf, Christofer H.

    1984-01-01

    Chemical compounds can be dissociated by contacting the same with a p/n type semi-conductor diode having visible light as its sole source of energy. The diode consists of low cost, readily available materials, specifically polycrystalline iron oxide doped with silicon in the case of the n-type semi-conductor electrode, and polycrystalline iron oxide doped with magnesium in the case of the p-type electrode. So long as the light source has an energy greater than 2.2 electron volts, no added energy source is needed to achieve dissociation.

  14. Electrolytic photodissociation of chemical compounds by iron oxide photochemical diodes

    DOEpatents

    Somorjai, Gabor A.; Leygraf, Christofer H.

    1985-01-01

    Chemical compounds can be dissociated by contacting the same with a p/n type semi-conductor photochemical diode having visible light as its sole source of energy. The photochemical diode consists of low cost, readily available materials, specifically polycrystalline iron oxide doped with silicon in the case of the n-type semi-conductor electrode, and polycrystalline iron oxide doped with magnesium in the case of the p-type electrode. So long as the light source has an energy greater than 2.2 electron volts, no added energy source is needed to achieve dissociation.

  15. Reduction of blood serum cholesterol

    NASA Technical Reports Server (NTRS)

    Winitz, M. (Inventor)

    1974-01-01

    By feeding a human subject as the sole source of sustenance a defined diet wherein the carbohydrate consists substantially entirely of glucose, maltose or a polysaccharide of glucose, the blood serum cholesterol level of the human subject is substantially reduced. If 25 percent of the carbohydrate is subsequently supplied in the form of sucrose, an immediate increase from the reduced level is observed. The remainder of the defined diet normally includes a source of amino acids, such as protein or a protein hydrolysate, vitamins, minerals and a source of essential fatty acid.

  16. Non-inferiority trials: are they inferior? A systematic review of reporting in major medical journals

    PubMed Central

    Morris, Tim P; Fielding, Katherine; Carpenter, James R; Phillips, Patrick P J

    2016-01-01

    Objective To assess the adequacy of reporting of non-inferiority trials alongside the consistency and utility of current recommended analyses and guidelines. Design Review of randomised clinical trials that used a non-inferiority design published between January 2010 and May 2015 in medical journals that had an impact factor >10 (JAMA Internal Medicine, Archives Internal Medicine, PLOS Medicine, Annals of Internal Medicine, BMJ, JAMA, Lancet and New England Journal of Medicine). Data sources Ovid (MEDLINE). Methods We searched for non-inferiority trials and assessed the following: choice of non-inferiority margin and justification of margin; power and significance level for sample size; patient population used and how this was defined; any missing data methods used and assumptions declared and any sensitivity analyses used. Results A total of 168 trial publications were included. Most trials concluded non-inferiority (132; 79%). The non-inferiority margin was reported for 98% (164), but less than half reported any justification for the margin (77; 46%). While most chose two different analyses (91; 54%) the most common being intention-to-treat (ITT) or modified ITT and per-protocol, a large number of articles only chose to conduct and report one analysis (65; 39%), most commonly the ITT analysis. There was lack of clarity or inconsistency between the type I error rate and corresponding CIs for 73 (43%) articles. Missing data were rarely considered with (99; 59%) not declaring whether imputation techniques were used. Conclusions Reporting and conduct of non-inferiority trials is inconsistent and does not follow the recommendations in available statistical guidelines, which are not wholly consistent themselves. Authors should clearly describe the methods used and provide clear descriptions of and justifications for their design and primary analysis. Failure to do this risks misleading conclusions being drawn, with consequent effects on clinical practice. PMID:27855102

  17. Only lasers can be used for low level laser therapy.

    PubMed

    Moskvin, Sergey Vladimirovich

    2017-12-01

    The question of lasers' exclusivity, as well as the degree of influence of special properties of low-intensity laser illumination (LILI), such as coherence, polarity and monochromaticity, on the effectiveness of low level laser therapy (LLLT) continues to cause arguments. The study analyzes publications from 1973 to 2016, in which laser and conventional light sources are compared, and the following conclusions are drawn. First, there are a lot of publications with incorrect comparison or unfounded statements. Secondly, other sources of light are often meant by LILI without any justification. Thirdly, all studies, in which the comparison is carried out correctly and close parameters of the impact and the model are used, have a firm conclusion that laser light is much more effective. Fourthly, it is uniquely identified that the most important parameter that determines the efficiency of lasers is monochromaticity, i.e., a much narrower spectral width than for all other light sources. Only laser light sources can be used for LLLT! © Author(s) 2017. This article is published with open access by China Medical University.

  18. The National Spallation Neutron Source (NSNS) Project

    NASA Astrophysics Data System (ADS)

    Appleton, Bill R.

    1997-05-01

    The need and justification for new sources and instrumentation in neutron science have been firmly established by numerous assessments since the early 1970s by the scientific community and the Department of Energy (DOE). In their 1996 budget, the DOE Office of Energy Research asked ORNL to lead the R&D and conceptual design effort for a next-generation spallation neutron source to be used for neutron scattering. To accomplish this, the NSNS collaboration involving five national laboratories (ANL, BNL, LANL, LBNL, and ORNL) has been formed. The NSNS reference design is for a 1-GeV linac and accumulator ring that delivers 1-MW proton beams in microsend pulses to a mercuty target; neutrons are produced by the spallation reaction, moderated, and guided into an experimental hall for neutron scattering. The design includes the necessary flexibility to upgrade the source in stages to significantly higher powers in the future and to expand the experimental capabilities. This talk will describe the origins at NSNS, the current funding status, progress on the technical design, user community input and the intended uses, and future prospects.

  19. Enrichments of methanotrophic-heterotrophic cultures with high poly-β-hydroxybutyrate (PHB) accumulation capacities.

    PubMed

    Zhang, Tingting; Wang, Xiaowei; Zhou, Jiti; Zhang, Yu

    2018-03-01

    Methanotrophic-heterotrophic communities were selectively enriched from sewage sludge to obtain a mixed culture with high levels of poly-β-hydroxybutyrate (PHB) accumulation capacity from methane. Methane was used as the carbon source, N 2 as sole nitrogen source, and oxygen and Cu content were varied. Copper proved essential for PHB synthesis. All cultures enriched with Cu could accumulate high content of PHB (43.2%-45.9%), while only small amounts of PHB were accumulated by cultures enriched without Cu (11.9%-17.5%). Batch assays revealed that communities grown with Cu and a higher O 2 content synthesized more PHB, which had a wider optimal CH 4 :O 2 range and produced a high PHB content (48.7%) even though in the presence of N 2 . In all methanotrophic-heterotrophic communities, both methanotrophic and heterotrophic populations showed the ability to accumulate PHB. Although methane was added as the sole carbon source, heterotrophs dominated with abundances between 77.2% and 85.6%. All methanotrophs detected belonged to type II genera, which formed stable communities with heterotrophs of different PHB production capacities. Copyright © 2017. Published by Elsevier B.V.

  20. Isolation of Bacteria Capable of Growth with 2-Methylisoborneol and Geosmin as the Sole Carbon and Energy Sources

    PubMed Central

    Guttman, Lior

    2012-01-01

    Using a relatively simple enrichment technique, geosmin and 2-methylisoborneol (MIB)-biodegrading bacteria were isolated from a digestion basin in an aquaculture unit. Comparison of 16S rRNA gene sequences affiliated one of the three isolates with the Gram-positive genus Rhodococcus, while the other two isolates were found to be closely related to the Gram-negative family Comamonadaceae (Variovorax and Comamonas). Growth rates and geosmin and MIB removal rates by the isolates were determined under aerated and nonaerated conditions in mineral medium containing either of the two compounds as the sole carbon and energy source. All isolates exhibited their fastest growth under aerobic conditions, with generation times ranging from 3.1 to 5.7 h, compared to generation times of up to 19.1 h in the nonaerated flasks. Incubation of the isolates with additional carbon sources caused a significant increase in their growth rates, while removal rates of geosmin and MIB were significantly lower than those for incubation with only geosmin or MIB. By fluorescence in situ hybridization, members of the genera Rhodococcus and Comamonas were detected in geosmin- and MIB-enriched sludge from the digestion basin. PMID:22081577

  1. Management of Electronic Test Equipment. Volume 4. DoD Policy.

    DTIC Science & Technology

    1986-07-01

    sources of supply , the PIL should not mandate sole source dependenc . but rather limit the variety to a minimum of two items. To clarify the controversy...equipment/ supplies on-hand, equipment readiness, and training. The resource area C-ratings are based on stated criteria. The criteria for equipment...respectively). The UNITREP leaves it up to the Military Services whether to include test equipment in the equipment/ supplies on-hand resource area. Although

  2. Lipid formation and γ-linolenic acid production by Mucor circinelloides and Rhizopus sp., grown on vegetable oil

    PubMed Central

    Tauk-Tornisielo, Sâmia M.; Arasato, Luciana S.; de Almeida, Alex F.; Govone, José S.; Malagutti, Eleni N.

    2009-01-01

    The fungi strains were tested in Bioscreen automated system to select the best nutritional source. Following, shaking submserse cultures were studied in media containing sole carbon or nitrogen source. The growth of these strains improved in media containing vegetable oil, with high concentration of lipids. The high concentration of γ-linolenic acid was obtained with M. circinelloides in culture containing sesame oil. PMID:24031370

  3. Formation and Fate of Bacterial Sulfonates

    DTIC Science & Technology

    1989-01-05

    sulfonates under phototrophic, anaerobic conditions’ Three cyanobacteria--a strain each of Synechococcus, Anabena, and Nostoc --have been examined for...their ability to utilize the sulfonate taurine as sole source of S for their oxygenic phototrophic growth; only Anabena and Nostoc were able to do so, and

  4. COMPARATIVE EVALUATION OF MTBE SITES ON LONG ISLAND

    EPA Science Inventory

    The aquifers of Long Island serve as the sole-source drinking water supply for approximately 3 million people. About 20 percent of this population obtains drinking water directly from the water table aquifer (Upper Glacial) whereas the remainder obtain their drinking water from d...

  5. 15 CFR 23.3 - Plan.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... children information in domestic penalty mail directed to the public and Federal employees. (b) The... newsletters, bulletins, etc. (d) Missing children information will not be placed on letter-size envelopes in... Children (National Center) will be the sole source from which the Department of Commerce will obtain the...

  6. 40 CFR 149.101 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... AQUIFERS Review of Projects Affecting the Edwards Underground Reservoir, A Designated Sole Source Aquifer... specifically provided, the term(s): (a) Act means the Public Health Service Act, as amended by the Safe Drinking Water Act, Public Law 93-523. (b) Contaminant means any physical, chemical, biological, or...

  7. 21 CFR 558.600 - Tiamulin.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... treated with tiamulin should not have access to feeds containing polyether ionophores (e.g., lasalocid... not been determined. (3) Use as sole source of tiamulin. (e) Conditions of use—(1) Swine. It is used... bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis and bacterial pneumonia caused by...

  8. Sports Facilities, Zapopan, Jalisco, Mexico.

    ERIC Educational Resources Information Center

    Amelar, Sarah

    2001-01-01

    Highlights a new K-12 school gymnasium in Mexico that changes and reacts to weather conditions, requires no air conditioning, and, on typical days, uses sunlight filtering through its ample clerestory as the sole source of illumination. Includes numerous photographs, a section drawing, and a site plan. (GR)

  9. 46 CFR 112.35-1 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-1 General. This subpart contains requirements applicable to emergency power installations having a manually controlled storage battery, diesel engine, or...

  10. 46 CFR 112.35-1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-1 General. This subpart contains requirements applicable to emergency power installations having a manually controlled storage battery, diesel engine, or...

  11. Characterization of medium-chain-length polyhydroxyalkanoate biosynthesis by Pseudomonas mosselii TO7 using crude glycerol.

    PubMed

    Liu, Ming-Hsu; Chen, Yi-Jr; Lee, Chia-Yin

    2018-03-01

    Polyhydroxyalkanoates (PHAs) are biopolyesters produced by microorganisms that are environmentally friendly. PHAs can be used to replace traditional plastic to reduce environmental pollution in various fields. PHA production costs are high because PHA must be produced from a carbon substrate. The purpose of this study was to find the strain that can used the BDF by-product as the sole carbon source to produce high amounts of medium-chain-length PHA. Three isolates were evaluated for potential PHA production by using biodiesel-derived crude glycerol as the sole carbon source. Among them, Pseudomonas mosselii TO7 yielded high PHA content. The PHA produced from P. mosselii TO7 were medium-chain-length-PHAs. The PHA content of 48% cell dry weight in 48 h with a maximum PHA productivity of 13.16 mg PHAs L -1  h -1 . The narrow polydispersity index value of 1.3 reflected the homogeneity of the polymer chain, which was conducive to industrial applications.

  12. Genetic Analysis of Benzothiophene Biodesulfurization Pathway of Gordonia terrae Strain C-6

    PubMed Central

    Lian, Kehui; Zhang, Yue; Tian, Huimei; Ji, Kaihua; Li, Guoqiang

    2013-01-01

    Sulfur can be removed from benzothiophene (BT) by some bacteria without breaking carbon-carbon bonds. However, a clear mechanism for BT desulfurization and its genetic components have not been reported in literatures so far. In this study, we used comparative transcriptomics to study differential expression of genes in Gordonia terrae C-6 cultured with BT or sodium sulfate as the sole source of sulfur. We found that 135 genes were up-regulated with BT relative to sodium sulfate as the sole sulfur source. Many of these genes encode flavin-dependent monooxygenases, alkane sulfonate monooxygenases and desulfinase, which perform similar functions to those involved in the 4S pathway of dibenzothiophene (DBT) biodesulfurization. Three of the genes were found to be located in the same operon, designated bdsABC. Cell extracts of pET28a-bdsABC transfected E. coli Rosetta (DE3) converted BT to a phenolic compound, identified as o-hydroxystyrene. These results advance our understanding of enzymes involved in the BT biodesulfurization pathway. PMID:24367657

  13. Phoma herbarum, a soil fungus able to grow on natural lignin and synthetic lignin (DHP) as sole carbon source and cause lignin degradation.

    PubMed

    Bi, Ran; Lawoko, Martin; Henriksson, Gunnar

    2016-08-01

    The fungus Phoma herbarum isolated from soil showed growth on highly pure lignin extracted from spruce wood and on synthetic lignin (DHP). The lignin remaining after cultivation was shown to have a lower molecular weight. The reduction in the numbers of ether linkages of the extracted lignins was also observed by derivatization followed by reductive cleavage (DFRC) in combination with (31)P NMR studies. The fungal strain showed an ability to degrade synthetic lignin by extracellular catalysts. GC-MS was applied to study the evolution of low molar mass adducts, e.g., monolignols and it was shown that a reduced coniferyl alcohol product was produced from DHP in a cell-free environment. The work has demonstrated the ability of soil microbes to grow on lignin as sole carbon source. The potential impact is in the production of low molar mass renewable phenols for material application.

  14. Financial Impact of Dual Vendor, Matrix Pricing, and Sole-Source Contracting on Implant Costs.

    PubMed

    Althausen, Peter L; Lapham, Joan; Mead, Lisa

    2016-12-01

    Implant costs comprise the largest proportion of operating room supply costs for orthopedic trauma care. Over the years, hospitals have devised several methods of controlling these costs with the help of physicians. With increasing economic pressure, these negotiations have a tremendous ability to decrease the cost of trauma care. In the past, physicians have taken no responsibility for implant pricing which has made cost control difficult. The reasons have been multifactorial. However, industry surgeon consulting fees, research support, and surgeon comfort with certain implant systems have played a large role in slowing adoption of cost-control measures. With the advent of physician gainsharing and comanagement agreements, physicians now have impetus to change. At our facility, we have used 3 methods for cost containment since 2009: dual vendor, matrix pricing, and sole-source contracting. Each has been increasingly successful, resulting in massive savings for the institution. This article describes the process and benefits of each model.

  15. Characterization and Genomic Analysis of a Highly Efficient Dibutyl Phthalate-Degrading Bacterium Gordonia sp. Strain QH-12.

    PubMed

    Jin, Decai; Kong, Xiao; Liu, Huijun; Wang, Xinxin; Deng, Ye; Jia, Minghong; Yu, Xiangyang

    2016-06-25

    A bacterial strain QH-12 isolated from activated sludge was identified as Gordonia sp. based on analysis of 16S rRNA gene sequence and was found to be capable of utilizing dibutyl phthalate (DBP) and other common phthalate esters (PAEs) as the sole carbon and energy source. The degradation kinetics of DBP under different concentrations by the strain QH-12 fit well with the modified Gompertz model (R² > 0.98). However, strain QH-12 could not utilize the major intermediate product phthalate (phthalic acid; PA) as the sole carbon and energy source, and only a little amount of PA was detected. The QH-12 genome analysis revealed the presence of putative hydrolase/esterase genes involved in PAEs-degradation but no phthalic acid catabolic gene cluster was found, suggesting that a novel degradation pathway of PAEs was present in Gordonia sp. QH-12. This information will be valuable for obtaining a more holistic understanding on diverse genetic mechanisms of PAEs-degrading Gordonia sp. strains.

  16. Two-dimensional isobutyl acetate production pathways to improve carbon yield

    PubMed Central

    Tashiro, Yohei; Desai, Shuchi H.; Atsumi, Shota

    2015-01-01

    For an economically competitive biological process, achieving high carbon yield of a target chemical is crucial. In biochemical production, pyruvate and acetyl-CoA are primary building blocks. When sugar is used as the sole biosynthetic substrate, acetyl-CoA is commonly generated by pyruvate decarboxylation. However, pyruvate decarboxylation during acetyl-CoA formation limits the theoretical maximum carbon yield (TMCY) by releasing carbon, and in some cases also leads to redox imbalance. To avoid these problems, we describe here the construction of a metabolic pathway that simultaneously utilizes glucose and acetate. Acetate is utilized to produce acetyl-CoA without carbon loss or redox imbalance. We demonstrate the utility of this approach for isobutyl acetate (IBA) production, wherein IBA production with glucose and acetate achieves a higher carbon yield than with either sole carbon source. These results highlight the potential for this multiple carbon source approach to improve the TMCY and balance redox in biosynthetic pathways. PMID:26108471

  17. The Race and Racism of the I.Q. Argument.

    ERIC Educational Resources Information Center

    Willhelm, Sidney M.

    A brief historical resume outlining the relationship between economics, racism, and intellectual justification for racism begins this paper, which notes that the I.Q. argument is a racist ideology in exactly the same way that Christianity, Darwinism, and Equality have been systems of justifications for America's racism. It fits the definition of…

  18. Is There a Need for Transcendental Arguments in Discourse Ethics?

    ERIC Educational Resources Information Center

    Johnston, James Scott

    2016-01-01

    In this essay, James Scott Johnston examines Jürgen Habermas's transcendental justification of his discourse theory of morality. According to Johnston, the application of Habermas's theory to educational issues often assumes that this justification is a cogent one. However, if the theory is to provide reasoned and appropriate guidance for…

  19. Academic Freedom: In Justification of a Universal Ideal

    ERIC Educational Resources Information Center

    Karran, Terence

    2009-01-01

    This article examines the justification for, and benefits of, academic freedom to academics, students, universities and the world at large. It surveys the development of the concept of academic freedom within Europe, more especially the impact of the reforms at the University of Berlin instigated by Wilhelm von Humboldt. Following from this, the…

  20. Frequency band justifications for passive sensors 10.0 to 385 GHz, chapter 2. [for monitoring earth resources and the environment

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Sensitivity requirements of the various measurements obtained by microwave sensors, and radiometry techniques are described. Analytical techniques applied to detailed sharing analyses are discussed. A bibliography of publications pertinent to the scientific justification of frequency requirements for passive microwave remote sensing is included.

  1. Using Empirical Evidence in the Process of Proving: The Case of Dynamic Geometry

    ERIC Educational Resources Information Center

    Guven, Bulent; Cekmez, Erdem; Karatas, Ilhan

    2010-01-01

    With the emergence of Dynamic Geometry Software (DGS), a theoretical gap between the acquisition (inductive) and the justification (deductive) of a mathematical statement has started a debate. Some educators believe that deductive proof in geometry should be abandoned in favour of an experimental approach to mathematical justification. This…

  2. 49 CFR 611.303 - Small Starts project justification criteria.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... and assign ratings for project justification, FTA will evaluate information developed locally through the planning, NEPA and project development processes. (1) The method used by FTA to evaluate and rate... ratings for each of the criteria in § 611.303(b)(1) through (6) will be expressed in terms of descriptive...

  3. 49 CFR 611.203 - New Starts project justification criteria.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... project justification, FTA will evaluate information developed locally through the planning and NEPA processes. (1) The method used by FTA to evaluate and rate projects will be a multiple measure approach by... each of the criteria in § 611.203(b)(1) through (6) will be expressed in terms of descriptive...

  4. 49 CFR 611.303 - Small Starts project justification criteria.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... and assign ratings for project justification, FTA will evaluate information developed locally through the planning, NEPA and project development processes. (1) The method used by FTA to evaluate and rate... ratings for each of the criteria in § 611.303(b)(1) through (6) will be expressed in terms of descriptive...

  5. 49 CFR 611.203 - New Starts project justification criteria.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... project justification, FTA will evaluate information developed locally through the planning and NEPA processes. (1) The method used by FTA to evaluate and rate projects will be a multiple measure approach by... each of the criteria in § 611.203(b)(1) through (6) will be expressed in terms of descriptive...

  6. 14 CFR 221.205 - Justification and explanation for certain fares.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... fares. 221.205 Section 221.205 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... Justification and explanation for certain fares. Any carrier or its agent must provide, as to any new or increased bundled or unbundled (whichever is lower) on-demand economy fare in a direct-service market, a...

  7. Extricating Justification Scheme Theory in Middle School Mathematical Problem Solving

    ERIC Educational Resources Information Center

    Matteson, Shirley; Capraro, Mary Margaret; Capraro, Robert M.; Lincoln, Yvonna S.

    2012-01-01

    Twenty middle grades students were interviewed to gain insights into their reasoning about problem-solving strategies using a Problem Solving Justification Scheme as our theoretical lens and the basis for our analysis. The scheme was modified from the work of Harel and Sowder (1998) making it more broadly applicable and accounting for research…

  8. Dewey's Ethical Justification for Public Deliberation Democracy

    ERIC Educational Resources Information Center

    Shook, John

    2013-01-01

    Interpretations of John Dewey's political theory grasp his respect for public deliberation, but typically overlook his ethical justification for democracy. Dewey gave two primary reasons why democracy is superior to other forms of government. First, a public educated in the tools of social intelligence can be more effective at managing their…

  9. Chinese Children's Justifications for Sharing Resources: Why Do We Have to Share?

    ERIC Educational Resources Information Center

    Wong, Mun

    2011-01-01

    Gilligan argued that Kohlberg's justice-based stage theory of morality reflects only one type of morality and does not consider people's tendency to use care-based moral judgements. This study examines Chinese children's tendency to use justice-based and care-based justifications for moral reasoning. Children's attitudes to conforming to the…

  10. Moving Students to "The Why?"

    ERIC Educational Resources Information Center

    Cioe, Michael; King, Sherryl; Ostien, Deborah; Pansa, Nancy; Staples, Megan

    2015-01-01

    Justification is a critical mathematical practice that must play a role in teaching and learning at all grade levels. Having students share their reasoning and explain how they know something is true or correct is the process of justification. The authors (a team of teachers and researchers) worked together for two years with an NSF-funded project…

  11. A grid to facilitate physics staffing justification.

    PubMed

    Klein, Eric E

    2009-12-03

    Justification of clinical physics staffing levels is difficult due to the lack of direction as how to equate clinical needs with the staffing levels and competency required. When a physicist negotiates staffing requests to administration, she/he often refers to American College of Radiology staffing level suggestions, and resources such as the Abt studies. This approach is often met with questions as to how to fairly derive the time it takes to perform tasks. The result is often insufficient and/or inexperienced staff handling complex and cumbersome tasks. We undertook development of a staffing justification grid to equate the clinical needs to the quantity and quality of staffing required. The first step is using the Abt study, customized to the clinical setting, to derive time per task multiplied by the anticipated number of such tasks. Inclusion of vacation, meeting, and developmental time may be incorporated along with allocated time for education and administration. This is followed by mapping the tasks to the level of competency/experience needed. For example, in an academic setting the faculty appointment levels correlate with experience. Non-staff personnel, such as IMRT QA technicians or clerical staff, should also be part of the equation. By using the staffing justification grid, we derived strong documentation to justify a substantial budget increase. The grid also proved useful when our clinical demands changed. Justification for physics staffing can be significantly strengthened with a properly developed data-based time and work analysis. A staffing grid is presented, along with a development methodology that facilitated our justification. Though our grid is for a large academic facility, the methodology can be extended to a non-academic setting, and to a smaller scale. This grid method not only equates the clinical needs with the quantity of staffing, but can also help generate the personnel budget, based on the type of staff and personnel required. The grid is easily adaptable when changes to the clinical environment change, such as an increase in IMRT or IGRT applications.

  12. Theoretical considerations for mapping activation in human cardiac fibrillation

    NASA Astrophysics Data System (ADS)

    Rappel, Wouter-Jan; Narayan, Sanjiv M.

    2013-06-01

    Defining mechanisms for cardiac fibrillation is challenging because, in contrast to other arrhythmias, fibrillation exhibits complex non-repeatability in spatiotemporal activation but paradoxically exhibits conserved spatial gradients in rate, dominant frequency, and electrical propagation. Unlike animal models, in which fibrillation can be mapped at high spatial and temporal resolution using optical dyes or arrays of contact electrodes, mapping of cardiac fibrillation in patients is constrained practically to lower resolutions or smaller fields-of-view. In many animal models, atrial fibrillation is maintained by localized electrical rotors and focal sources. However, until recently, few studies had revealed localized sources in human fibrillation, so that the impact of mapping constraints on the ability to identify rotors or focal sources in humans was not described. Here, we determine the minimum spatial and temporal resolutions theoretically required to detect rigidly rotating spiral waves and focal sources, then extend these requirements for spiral waves in computer simulations. Finally, we apply our results to clinical data acquired during human atrial fibrillation using a novel technique termed focal impulse and rotor mapping (FIRM). Our results provide theoretical justification and clinical demonstration that FIRM meets the spatio-temporal resolution requirements to reliably identify rotors and focal sources for human atrial fibrillation.

  13. Isolation and Characterization of Rhamnolipid-Producing Bacterial Strains from a Biodiesel Facility

    USDA-ARS?s Scientific Manuscript database

    Novel strains of rhamnolipid-producing bacteria were isolated from soils at a biodiesel facility on the basis of their ability to grow on glycerol as a sole carbon source. Strains were identified as Acinetobacter calcoaceticus, Enterobacter asburiae, E. hormaecheii, Pantoea stewartii and Pseudomona...

  14. 48 CFR 8.405-6 - Limiting sources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... or BPA with an estimated value exceeding the micro-purchase threshold not placed or established in... Schedule ordering procedures. The original order or BPA must not have been previously issued under sole... order or BPA exceeding the simplified acquisition threshold. (2) Posting. (i) Within 14 days after...

  15. 48 CFR 8.405-6 - Limiting sources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... or BPA with an estimated value exceeding the micro-purchase threshold not placed or established in... Schedule ordering procedures. The original order or BPA must not have been previously issued under sole... order or BPA exceeding the simplified acquisition threshold. (2) Posting. (i) Within 14 days after...

  16. 48 CFR 8.405-6 - Limiting sources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... or BPA with an estimated value exceeding the micro-purchase threshold not placed or established in... Schedule ordering procedures. The original order or BPA must not have been previously issued under sole... order or BPA exceeding the simplified acquisition threshold. (2) Posting. (i) Within 14 days after...

  17. 48 CFR 8.405-6 - Limiting sources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... or BPA with an estimated value exceeding the micro-purchase threshold not placed or established in... Schedule ordering procedures. The original order or BPA must not have been previously issued under sole... order or BPA exceeding the simplified acquisition threshold. (2) Posting. (i) Within 14 days after...

  18. 46 CFR 112.30-5 - Transfer of emergency loads.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-5 Transfer of emergency loads. If there is a reduction of potential of the...

  19. 46 CFR 112.35-5 - Manually started emergency systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....35-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-5 Manually...

  20. 46 CFR 112.35-5 - Manually started emergency systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ....35-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-5 Manually...

  1. 46 CFR 112.30-5 - Transfer of emergency loads.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-5 Transfer of emergency loads. If there is a reduction of potential of the...

  2. 46 CFR 112.35-5 - Manually started emergency systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....35-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-5 Manually...

  3. 46 CFR 112.35-5 - Manually started emergency systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....35-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-5 Manually...

  4. 46 CFR 112.30-5 - Transfer of emergency loads.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-5 Transfer of emergency loads. If there is a reduction of potential of the...

  5. 46 CFR 112.30-5 - Transfer of emergency loads.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-5 Transfer of emergency loads. If there is a reduction of potential of the...

  6. 46 CFR 112.35-5 - Manually started emergency systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....35-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Manually Controlled Emergency Systems Having a Storage Battery or a Diesel Engine or Gas Turbine Driven Generator as the Sole Emergency Power Source § 112.35-5 Manually...

  7. 46 CFR 112.30-5 - Transfer of emergency loads.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Systems Having an Automatically Connected Storage Battery as the Sole Emergency Power Source § 112.30-5 Transfer of emergency loads. If there is a reduction of potential of the...

  8. Impact of cascadia subduction zone earthquake on the seismic evaluation criteria of bridges : technical report : SPR 770.

    DOT National Transportation Integrated Search

    2016-12-01

    A large magnitude long duration subduction earthquake is impending in the Pacific Northwest, which lies near the : Cascadia Subduction Zone (CSZ). Great subduction zone earthquakes are the largest earthquakes in the world and are the sole source : zo...

  9. 46 CFR 183.354 - Battery installations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Battery installations. 183.354 Section 183.354 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.354 Battery installations. (a) Large batteries. Each large battery installation must be located in a locker, room or enclosed box solely...

  10. Jose Vasconcelos, Philosopher-Librarian.

    ERIC Educational Resources Information Center

    Christensen, Paul Martin

    Jose Vasconcelos (1882-1959), a major figure of modern Mexican education, also was instrumental in the development of the field of librarianship in Mexico. This research paper presents Vasconcelos' philosophy of librarianship through a detailed study of his writings and a review of major secondary sources. Relying solely on the subjective…

  11. Psychological Testing and Psychological Assessment: A Review of Evidence and Issues.

    ERIC Educational Resources Information Center

    Meyer, Gregory J.; Finn, Stephen E.; Eyde, Lorraine D.; Kay, Gary G.; Moreland, Kevin L.; Dies, Robert R.; Eisman, Elena J.; Kubiszyn, Tom W.; Reed, Geoffrey M.

    2001-01-01

    Summarizes issues associated with psychological assessment, concluding that: psychological test validity is strong and is comparable to medical test validity; distinct assessment methods provide unique sources of information; and clinicians who rely solely on interviews are prone to incomplete understandings. Suggests that multimethod assessment…

  12. The Image of Africa in Our Classrooms.

    ERIC Educational Resources Information Center

    Pahl, Ronald H.

    1995-01-01

    Argues that the media portrayal of Africa remains highly selective, focusing almost solely on negative and violent stories. Positive stories (local initiatives, political reform) go unreported as does much of the Western powers involvement in famine and destruction. Includes a list of sources on African current affairs. (MJP)

  13. 46 CFR 183.354 - Battery installations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Battery installations. 183.354 Section 183.354 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.354 Battery installations. (a) Large batteries. Each large battery installation must be located in a locker, room or enclosed box solely...

  14. 46 CFR 183.354 - Battery installations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Battery installations. 183.354 Section 183.354 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.354 Battery installations. (a) Large batteries. Each large battery installation must be located in a locker, room or enclosed box solely...

  15. 46 CFR 183.354 - Battery installations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Battery installations. 183.354 Section 183.354 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.354 Battery installations. (a) Large batteries. Each large battery installation must be located in a locker, room or enclosed box solely...

  16. 46 CFR 183.354 - Battery installations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Battery installations. 183.354 Section 183.354 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.354 Battery installations. (a) Large batteries. Each large battery installation must be located in a locker, room or enclosed box solely...

  17. 40 CFR 149.111 - Funding to redesigned projects.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 23 2011-07-01 2011-07-01 false Funding to redesigned projects. 149.111 Section 149.111 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER... Designated Sole Source Aquifer in the San Antonio, Texas Area § 149.111 Funding to redesigned projects. After...

  18. 48 CFR 2901.603-70 - Responsibility of other government personnel.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... buying process, and execution of the contract rests with the contracting officer. (b) Personnel... obligation. However, DOL personnel who must use the contracting process to accomplish their programs must... and open competition are satisfied to the maximum extent practicable. Sole source purchases may only...

  19. A fungal transcription factor essential for starch degradation affects integration of carbon and nitrogen metabolism

    DOE PAGES

    Xiong, Yi; Wu, Vincent W.; Lubbe, Andrea; ...

    2017-05-03

    In Neurospora crassa, the transcription factor COL-26 functions as a regulator of glucose signaling and metabolism. Its loss leads to resistance to carbon catabolite repression. Here, we report that COL-26 is necessary for the expression of amylolytic genes in N. crassa and is required for the utilization of maltose and starch. Additionally, the Δcol-26 mutant shows growth defects on preferred carbon sources, such as glucose, an effect that was alleviated if glutamine replaced ammonium as the primary nitrogen source. This rescue did not occur when maltose was used as a sole carbon source. Transcriptome and metabolic analyses of the Δcol-26more » mutant relative to its wild type parental strain revealed that amino acid and nitrogen metabolism, the TCA cycle and GABA shunt were adversely affected. Phylogenetic analysis showed a single col-26 homolog in Sordariales, Ophilostomatales, and the Magnaporthales, but an expanded number of col-26 homologs in other filamentous fungal species. Deletion of the closest homolog of col-26 in Trichoderma reesei, bglR, resulted in a mutant with similar preferred carbon source growth deficiency, and which was alleviated if glutamine was the sole nitrogen source, suggesting conservation of COL-26 and BglR function. Our finding provides novel insight into the role of COL-26 for utilization of starch and in integrating carbon and nitrogen metabolism for balanced metabolic activities for optimal carbon and nitrogen distribution.« less

  20. A fungal transcription factor essential for starch degradation affects integration of carbon and nitrogen metabolism

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xiong, Yi; Wu, Vincent W.; Lubbe, Andrea

    In Neurospora crassa, the transcription factor COL-26 functions as a regulator of glucose signaling and metabolism. Its loss leads to resistance to carbon catabolite repression. Here, we report that COL-26 is necessary for the expression of amylolytic genes in N. crassa and is required for the utilization of maltose and starch. Additionally, the Δcol-26 mutant shows growth defects on preferred carbon sources, such as glucose, an effect that was alleviated if glutamine replaced ammonium as the primary nitrogen source. This rescue did not occur when maltose was used as a sole carbon source. Transcriptome and metabolic analyses of the Δcol-26more » mutant relative to its wild type parental strain revealed that amino acid and nitrogen metabolism, the TCA cycle and GABA shunt were adversely affected. Phylogenetic analysis showed a single col-26 homolog in Sordariales, Ophilostomatales, and the Magnaporthales, but an expanded number of col-26 homologs in other filamentous fungal species. Deletion of the closest homolog of col-26 in Trichoderma reesei, bglR, resulted in a mutant with similar preferred carbon source growth deficiency, and which was alleviated if glutamine was the sole nitrogen source, suggesting conservation of COL-26 and BglR function. Our finding provides novel insight into the role of COL-26 for utilization of starch and in integrating carbon and nitrogen metabolism for balanced metabolic activities for optimal carbon and nitrogen distribution.« less

  1. Independent Component Analysis-motivated Approach to Classificatory Decomposition of Cortical Evoked Potentials

    PubMed Central

    Smolinski, Tomasz G; Buchanan, Roger; Boratyn, Grzegorz M; Milanova, Mariofanna; Prinz, Astrid A

    2006-01-01

    Background Independent Component Analysis (ICA) proves to be useful in the analysis of neural activity, as it allows for identification of distinct sources of activity. Applied to measurements registered in a controlled setting and under exposure to an external stimulus, it can facilitate analysis of the impact of the stimulus on those sources. The link between the stimulus and a given source can be verified by a classifier that is able to "predict" the condition a given signal was registered under, solely based on the components. However, the ICA's assumption about statistical independence of sources is often unrealistic and turns out to be insufficient to build an accurate classifier. Therefore, we propose to utilize a novel method, based on hybridization of ICA, multi-objective evolutionary algorithms (MOEA), and rough sets (RS), that attempts to improve the effectiveness of signal decomposition techniques by providing them with "classification-awareness." Results The preliminary results described here are very promising and further investigation of other MOEAs and/or RS-based classification accuracy measures should be pursued. Even a quick visual analysis of those results can provide an interesting insight into the problem of neural activity analysis. Conclusion We present a methodology of classificatory decomposition of signals. One of the main advantages of our approach is the fact that rather than solely relying on often unrealistic assumptions about statistical independence of sources, components are generated in the light of a underlying classification problem itself. PMID:17118151

  2. A fungal transcription factor essential for starch degradation affects integration of carbon and nitrogen metabolism

    PubMed Central

    Xiong, Yi; Qin, Lina; Kennedy, Megan; Bauer, Diane; Barry, Kerrie; Northen, Trent R.; Grigoriev, Igor V.

    2017-01-01

    In Neurospora crassa, the transcription factor COL-26 functions as a regulator of glucose signaling and metabolism. Its loss leads to resistance to carbon catabolite repression. Here, we report that COL-26 is necessary for the expression of amylolytic genes in N. crassa and is required for the utilization of maltose and starch. Additionally, the Δcol-26 mutant shows growth defects on preferred carbon sources, such as glucose, an effect that was alleviated if glutamine replaced ammonium as the primary nitrogen source. This rescue did not occur when maltose was used as a sole carbon source. Transcriptome and metabolic analyses of the Δcol-26 mutant relative to its wild type parental strain revealed that amino acid and nitrogen metabolism, the TCA cycle and GABA shunt were adversely affected. Phylogenetic analysis showed a single col-26 homolog in Sordariales, Ophilostomatales, and the Magnaporthales, but an expanded number of col-26 homologs in other filamentous fungal species. Deletion of the closest homolog of col-26 in Trichoderma reesei, bglR, resulted in a mutant with similar preferred carbon source growth deficiency, and which was alleviated if glutamine was the sole nitrogen source, suggesting conservation of COL-26 and BglR function. Our finding provides novel insight into the role of COL-26 for utilization of starch and in integrating carbon and nitrogen metabolism for balanced metabolic activities for optimal carbon and nitrogen distribution. PMID:28467421

  3. [The theory of mechanical activity of lungs--a creation history, the present and development prospects].

    PubMed

    Tetenev, F F; Tetenev, K F

    2014-01-01

    In article the history of creation of the doctrine about respiratory movements of lungs, history of classical mechanics of breathing is stated. Supervision of the paradoxical facts which became a basis for hypothesis creation, then the theory of mechanical activity of lungs are presented. The facts proving mechanical activity of lungs on an inspiration and an expiration are given. Options of interaction of intra pulmonary and extra pulmonary sources of mechanical energy are considered. Theoretical justification for development of the new direction of studying of physiology of mechanical movements of the internal which does not have own skeleton is stated.

  4. Characterisation of a resolution enhancing image inversion interferometer.

    PubMed

    Wicker, Kai; Sindbert, Simon; Heintzmann, Rainer

    2009-08-31

    Image inversion interferometers have the potential to significantly enhance the lateral resolution and light efficiency of scanning fluorescence microscopes. Self-interference of a point source's coherent point spread function with its inverted copy leads to a reduction in the integrated signal for off-axis sources compared to sources on the inversion axis. This can be used to enhance the resolution in a confocal laser scanning microscope. We present a simple image inversion interferometer relying solely on reflections off planar surfaces. Measurements of the detection point spread function for several types of light sources confirm the predicted performance and suggest its usability for scanning confocal fluorescence microscopy.

  5. 48 CFR 306.304 - Approval of the justification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... where the individual designated as the CA does not meet the requirements of FAR 6.304 (a)(3)(ii). This... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA shall indicate their review of, and concurrence with, the justification by signing the JOFOC. (a) The...

  6. 48 CFR 306.304 - Approval of the justification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... where the individual designated as the CA does not meet the requirements of FAR 6.304 (a)(3)(ii). This... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA shall indicate their review of, and concurrence with, the justification by signing the JOFOC. (a) The...

  7. 48 CFR 306.304 - Approval of the justification.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... where the individual designated as the CA does not meet the requirements of FAR 6.304 (a)(3)(ii). This... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA shall indicate their review of, and concurrence with, the justification by signing the JOFOC. (a) The...

  8. 48 CFR 306.304 - Approval of the justification.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... where the individual designated as the CA does not meet the requirements of FAR 6.304 (a)(3)(ii). This... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA shall indicate their review of, and concurrence with, the justification by signing the JOFOC. (a) The...

  9. Middle School Students' Responses to Two-Tier Tasks

    ERIC Educational Resources Information Center

    Haja, Shajahan; Clarke, David

    2011-01-01

    The structure of two-tier testing is such that the first tier consists of a multiple-choice question and the second tier requires justifications for choices of answers made in the first tier. This study aims to evaluate two-tier tasks in "proportion" in terms of students' capacity to write and select justifications and to examine the effect of…

  10. Education as a Public Good: Justification and Avenues of Values Integration into Management of Ugandan School Discipline

    ERIC Educational Resources Information Center

    Sekiwu, Denis; Botha, M. M.

    2014-01-01

    This qualitative study employs grounded theory and the Wilsonian concept analysis, as interpretative paradigms, to examine participants' voices on the justification and avenues of values integration into management of school discipline in Uganda. By using John Dewey's educational philosophy [pragmatism] as the theoretical lens for the study, we…

  11. Young Children's Ideas about the Nature, Causes, Justification, and Alleviation of Poverty

    ERIC Educational Resources Information Center

    Chafel, Judith A.; Neitzel, Carin

    2005-01-01

    Sixty-four 8-year-old boys and girls from urban and rural settings and representing different races and socioeconomic status backgrounds responded to questions about the nature, causes, justification, and alleviation of poverty. Much of what the children said indicated that they had not yet internalized prevailing adult norms and values about the…

  12. Beyond Competence and Performance: Children's Class Inclusion Strategies, Superordinate Class Cues, and Verbal Justifications.

    ERIC Educational Resources Information Center

    Chapman, Michael; McBride, Michelle L.

    1992-01-01

    Children of 4 to 10 years of age were given 2 class inclusion tasks. Younger children's performance was inflated by guessing. Scores were higher in the marked task than in the unmarked task as a result of differing rates of inclusion logic. Children's verbal justifications closely approximated estimates of their true competence. (GLR)

  13. The Labours of Hercules: Ethical Embodiment and an Erasmian Justification for Higher Education

    ERIC Educational Resources Information Center

    De Barros, Eric L.

    2014-01-01

    In the early 1990s, a popular American dorm-room poster luminously asserted crass materialism as "JUSTIFICATION FOR HIGHER EDUCATION". Self-consciously premised on the paradoxical success of my failure or failure of my success as a professor of Renaissance literature and culture, this essay draws on Erasmus's educational theory of…

  14. 30 CFR 203.84 - What is in a net revenue and relief justification report?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... justification report? This report presents cash flow data for 12 qualifying months, using the format specified... having some production. (a) The cash flow table you submit must include historical data for: (1) Lease... allowable costs; and (5) Transportation and processing costs. (b) Do not include in your cash flow table the...

  15. 30 CFR 203.4 - How do the provisions in this part apply to different types of leases and projects?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... justification report (prescribed format) X (3) Economic viability and relief justification report (Royalty Suspension Viability Program (RSVP) model inputs justified with Geological and Geophysical (G&G), Engineering... template) (6) Determined to be economic only with relief X X X (d) The following table indicates by an X...

  16. 30 CFR 203.4 - How do the provisions in this part apply to different types of leases and projects?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... justification report (prescribed format) X (3) Economic viability and relief justification report (Royalty Suspension Viability Program (RSVP) model inputs justified with Geological and Geophysical (G&G), Engineering...) (6) Determined to be economic only with relief X X X (d) The following table indicates by an X, and...

  17. 30 CFR 203.4 - How do the provisions in this part apply to different types of leases and projects?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... justification report (prescribed format) X (3) Economic viability and relief justification report (Royalty Suspension Viability Program (RSVP) model inputs justified with Geological and Geophysical (G&G), Engineering...) (6) Determined to be economic only with relief X X X (d) The following table indicates by an X, and...

  18. 30 CFR 203.85 - What is in an economic viability and relief justification report?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What is in an economic viability and relief... Oil, Gas, and Sulfur General Required Reports § 203.85 What is in an economic viability and relief... your own model and results. The economic viability and relief justification report must contain the...

  19. 30 CFR 203.4 - How do the provisions in this part apply to different types of leases and projects?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... justification report (prescribed format) X (3) Economic viability and relief justification report (Royalty Suspension Viability Program (RSVP) model inputs justified with Geological and Geophysical (G&G), Engineering...) (6) Determined to be economic only with relief X X X (d) The following table indicates by an X, and...

  20. A Reply on Behalf of the Relativist to Mark Mason's Justification of Universal Ethical Principles

    ERIC Educational Resources Information Center

    MacKenzie, Jim

    2007-01-01

    Mark Mason, in his "A Justification, After the Postmodern Turn, of Universal Ethical Principles and Educational Ideals" Educational Philosophy and Theory, 37 (2005), attempts to justify transcultural multiculturalism. In this paper I argue that he fails to refute moral relativism, and that multiculturalism as he interprets it is not morally…

  1. An Examination of Connections in Mathematical Processes in Students' Problem Solving: Connections between Representing and Justifying

    ERIC Educational Resources Information Center

    Stylianou, Despina A.

    2013-01-01

    Representation and justification are two central "mathematical practices". In the past, each has been examined to gain insights in the functions that they have in students' mathematical problem solving. Here, we examine the ways that representation and justification interact and influence the development of one another. We focus on the…

  2. Epistemic Beliefs about Justification Employed by Physics Students and Faculty in Two Different Problem Contexts

    ERIC Educational Resources Information Center

    Mercan, Fatih Caglayan

    2012-01-01

    This study examines the epistemic beliefs about justification employed by physics undergraduate and graduate students and faculty in the context of solving a standard classical physics problem and a frontier physics problem. Data were collected by a think-aloud problem solving session followed by a semi-structured interview conducted with 50…

  3. Developing an Understanding of Children's Justifications for the Circle Area Formula

    ERIC Educational Resources Information Center

    O'Dell, Jenna R.; Rupnow, Theodore J.; Cullen, Craig J.; Barrett, Jeffrey E.; Clements, Douglas H.; Sarama, Julie; Van Dine, Douglas W.

    2016-01-01

    In this study we investigated eighth grade students' informal justification for the circle area formula to expand accounts of the measurement knowledge for middle-school age students. Data were collected during three paired interviews of a three-year teaching experiment. Here we describe schemes students exhibited as they operated on measurement…

  4. 48 CFR Appendix I to Chapter 15 - Environmental Protection Agency; Class Justification for Other Than Full and Open Competition in...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Environmental Protection... Regulations System ENVIRONMENTAL PROTECTION AGENCY Ch. 15, App. I Appendix I to Chapter 15—Environmental Protection Agency; Class Justification for Other Than Full and Open Competition in Acquisitions From the...

  5. Can one do good medical ethics without principles?

    PubMed

    Macklin, Ruth

    2015-01-01

    The criteria for determining what it is to do good medical ethics are the quality of ethical analysis and ethical justifications for decisions and actions. Justifications for decisions and actions rely on ethical principles, be they the 'famous four' or subsidiary ethical principles relevant to specific contexts. Examples from clinical ethics, research ethics and public health ethics reveal that even when not stated explicitly, principles are involved in ethical justifications. Principles may come into conflict, however, and the resolution of an ethical dilemma requires providing good reasons for preferring one principle over another. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  6. Adolescent judgments and reasoning about the failure to include peers with social disabilities.

    PubMed

    Bottema-Beutel, Kristen; Li, Zhushan

    2015-06-01

    Adolescents with autism spectrum disorder often do not have access to crucial peer social activities. This study examines how typically developing adolescents evaluate decisions not to include a peer based on disability status, and the justifications they apply to these decisions. A clinical interview methodology was used to elicit judgments and justifications across four contexts. We found adolescents are more likely to judge the failure to include as acceptable in personal as compared to public contexts. Using logistic regression, we found that adolescents are more likely to provide moral justifications as to why failure to include is acceptable in a classroom as compared to home, lab group, and soccer practice contexts. Implications for intervention are also discussed.

  7. Engineering the Space Age: A Rocket Scientist Remembers

    DTIC Science & Technology

    2008-07-01

    energy sources -Research I. Title. 629.130092-dc22 Disclaimer Opinions, conclusions, and recommendations expressed or implied within are solely those of the...technical armed forces oc- 12 AERONAUTICAL ENGINEERING cupation specialty and keep flying. At the time, the atomic bombs were bulky and heavy and could only...way to learn about the F-84 aircraft. A welcome respite occurred when Major Wailer sent me to RAC to monitor a test to find the source and correct the

  8. Evaluation of a Recombinant Escherichia coli Strain that Uses the Sarin Simulant Isopropylmethylphosphonic Acid (IMPA) as a Sole Carbon and Phosphate Source

    DTIC Science & Technology

    2016-04-01

    phosphate use by these recombinant strains was evaluated because carbon use by these strains is still undergoing optimization by LBNL. The E . coli ...plasmids, had successful growth when transformed into a different E . coli background, which correlated with IMPA degradation. Ultimately, the...transformed E . coli strains, optimized at ECBC, were able to grow using IMPA as the phosphate source. 15. SUBJECT TERMS Acetylcholinesterase (AChE

  9. Isolation and Characterization of Anaerobic Bacteria for Symbiotic Recycling of Uric Acid Nitrogen in the Gut of Various Termites

    PubMed Central

    Thong-On, Arunee; Suzuki, Katsuyuki; Noda, Satoko; Inoue, Jun-ichi; Kajiwara, Susumu; Ohkuma, Moriya

    2012-01-01

    Recycling of the nitrogenous waste uric acid (UA) of wood-feeding termites by their gut bacteria is one of the significant aspects of symbiosis for the conservation of nitrogen sources. Diverse anaerobic UA-degrading bacteria comprising 16 species were isolated from the gut of eight termite species, and were assigned to Clostridia, Enterobacteriaceae, and low G+C Gram-positive cocci. UA-degrading Clostridia had never been isolated from termite guts. UA-degrading ability was sporadically distributed among phylogenetically various culturable anaerobic bacteria from termite guts. A strain of Clostridium sp., which was commonly isolated from three termite species and represented a probable new species in cluster XIVa of clostridia, utilized UA as a nitrogen source but not as a sole carbon and energy source. This feature is in clear contrast to that of well-studied purinolytic clostridia or previously isolated UA degraders from termite guts, which also utilize UA as a sole carbon and energy source. Ammonia is the major nitrogenous product of UA degradation. Various purines stimulated the growth of this strain when added to an otherwise growth-limiting, nitrogen poor medium. The bacterial species involved the recycling of UA nitrogen in the gut microbial community of termites are more diverse in terms of both taxonomy and nutritional physiology than previously recognized. PMID:22791052

  10. 21 CFR 520.2640 - Tylosin.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... use—(1) Chickens—(i) Amount. 2 grams per gallon for 1 to 5 days as the sole source of drinking water. Treated chickens should consume enough medicated drinking water to provide 50 milligrams (mg) tylosin per... sensitive to tylosin at time of vaccination or other stress in chickens. For the control of chronic...

  11. 21 CFR 520.2640 - Tylosin.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Amount. 2 grams per gallon for 1 to 5 days as the sole source of drinking water. Treated chickens should consume enough medicated drinking water to provide 50 milligrams (mg) tylosin per pound of body weight per... of vaccination or other stress in chickens. For the control of chronic respiratory disease (CRD...

  12. AACRAO's Basic Guide to Enrollment Management

    ERIC Educational Resources Information Center

    Westman, Craig

    2005-01-01

    The sole purpose of this book is to provide a primer or "how-to" resource for new or seasoned enrollment managers. Its core chapters are practical applications of Strategic Enrollment Management (SEM) best practices. While incorporating some secondary source referencing, the dialogue primarily outlines how making some basic adjustments to business…

  13. 48 CFR 217.7505 - Limitations on price increases.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Limitations on price... Acquisition of Replenishment Parts 217.7505 Limitations on price increases. This section provides implementing... award, on a sole source basis, a contract for any centrally managed replenishment part when the price of...

  14. Effects of artemisinin and Artemisia annua extracts on Haemonchus contortus in gerbils (Meriones unguiculatus)

    USDA-ARS?s Scientific Manuscript database

    Haemonchus contortus is a blood-sucking abomasal parasite of small ruminants that is responsible for major losses to producers worldwide. Resistance of this nematode to commercial anthelmintics has produced a demand for alternative control methods. Artemisia annua is the sole commercial source of ...

  15. 48 CFR 619.811-1 - Sole source.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... contracting activity shall include SBA's requirement number on the award document. (4) A single award document... sign the contract as a third party. The 8(a) contractor's signature shall be placed on the award... and open competition. (2) The contracting officer shall insert FAR 52.219-14, Limitations on...

  16. 48 CFR 619.811-1 - Sole source.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... contracting activity shall include SBA's requirement number on the award document. (4) A single award document... sign the contract as a third party. The 8(a) contractor's signature shall be placed on the award... and open competition. (2) The contracting officer shall insert FAR 52.219-14, Limitations on...

  17. 76 FR 55947 - Industrial Relations Promotion Project, Phase II in Vietnam

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ... to award sole source (Cooperative Agreement). SUMMARY: The U.S. Department of Labor (USDOL), Bureau.../Nathan Group LLC (DAI) for the purpose of implementing a program to strengthen compliance with... to perform the type of activity to be funded.. DAI, through its Industrial Relations Promotion...

  18. 46 CFR 129.356 - Battery installations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Battery installations. 129.356 Section 129.356 Shipping... INSTALLATIONS Power Sources and Distribution Systems § 129.356 Battery installations. (a) Large. Each large battery-installation must be located in a locker, room, or enclosed box dedicated solely to the storage of...

  19. Cellobiose fermenting yeast produces varied forms of native ß-glucosidase

    USDA-ARS?s Scientific Manuscript database

    The rapid growing yeast strain NRRL Y-50464 is robust to environmental stress and resistant to 2-furaldehyde (furfural) and 5-[hydroxymethyl]-2-furaldehyde (HMF). It is able to utilize cellobiose as its sole source of carbon and produces ethanol from lignocellulosic biomass by simultaneous saccharif...

  20. OXIDATION OF BIPHENYL BY A MULTICOMPONENT ENZYME SYSTEM FROM PSEUDOMONAS SP. STRAIN LB400

    EPA Science Inventory

    Pseudomonas sp. strain LB400 grows on biphenyl as the sole carbon and energy source. This organism also cooxidizes several chlorinated biphenyl congeners. Biphenyl dioxygenase activity in cell extract required addition of NAD(P)H as an electron donor for the conversion of bipheny...

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